<110> Human Genome Sciences, Inc.

<120> Nucleic Acids, Proteins and Antibodies

<130> PA131PCT

<140> Unassigned
<141> 2001-05-18

<150> 60/205,515
<151> 2000-05-19

<160> 2820

<170> PatentIn Ver. 2.0

<210> 1
<211> 733
<212> DNA
<213> Homo sapiens

<400> 1
gggatccgga gcccaaatct tctgacaaaa ctcacacatg cccaccgtgc ccagcacctg     60
aattcgaggg tgcaccgtca gtcttcctct tccccccaaa acccaaggac accctcatga    120
tctcccggac tcctgaggtc acatgcgtgg tggtggacgt aagccacgaa gaccctgagg    180
tcaagttcaa ctggtacgtg gacggcgtgg aggtgcataa tgccaagaca aagccgcggg    240
aggagcagta caacagcacg taccgtgtgg tcagcgtcct caccgtcctg caccaggact    300
ggctgaatgg caaggagtac aagtgcaagg tctccaacaa agccctccca acccccatcg    360
agaaaaccat ctccaaagcc aaagggcagc cccgagaacc acaggtgtac accctgcccc    420
catcccggga tgagctgacc aagaaccagg tcagcctgac ctgcctggtc aaaggcttct    480
atccaagcga catcgccgtg gagtgggaga gcaatgggca gccggagaac aactacaaga    540
ccacgcctcc cgtgctggac tccgacggct ccttcttcct ctacagcaag ctcaccgtgg    600
acaagagcag gtggcagcag gggaacgtct tctcatgctc cgtgatgcat gaggctctgc    660
acaaccacta cacgcagaag agcctctccc tgtctccggg taaatgagtg cgacggccgc    720
gactctagag gat                                                       733

<210> 2
<211> 5
<212> PRT
<213> Homo sapiens

<220>
<221> Site
<222> (3)
<223> Xaa equals any of the twenty naturally ocurring L-amino acids

<400> 2
Trp Ser Xaa Trp Ser
  1               5

<210> 3
<211> 86
<212> DNA
<213> Artificial Sequence

<220>
<221> Primer_Bind
<223> Synthetic sequence with 4 tandem copies of the GAS binding site 
      found in the IRF1 promoter (Rothman et al., Immunity 1:457-468 
      (1994)), 18 nucleotides complementary to the SV40 early promoter,
      and a Xho I restriction site.

<400> 3
gcgcctcgag atttccccga aatctagatt tccccgaaat gatttccccg aaatgatttc     60
cccgaaatat ctgccatctc aattag                                          86

<210> 4
<211> 27
<212> DNA
<213> Artificial Sequence

<220>
<221> Primer_Bind
<223> Synthetic sequence complementary to the SV40 promter; includes a
      Hind III restriction site.

<400> 4
gcggcaagct ttttgcaaag cctaggc                                         27

<210> 5
<211> 271
<212> DNA
<213> Artificial Sequence

<220>
<221> Protein_Bind
<223> Synthetic promoter for use in biological assays; includes GAS
      binding sites found in the IRF1 promoter (Rothman et al., Immunity
      1:457-468 (1994)).

<400> 5
ctcgagattt ccccgaaatc tagatttccc cgaaatgatt tccccgaaat gatttccccg     60 
aaatatctgc catctcaatt agtcagcaac catagtcccg cccctaactc cgcccatccc    120
gcccctaact ccgcccagtt ccgcccattc tccgccccat ggctgactaa ttttttttat    180
ttatgcagag gccgaggccg cctcggcctc tgagctattc cagaagtagt gaggaggctt    240
ttttggaggc ctaggctttt gcaaaaagct t                                   271

<210> 6
<211> 32
<212> DNA
<213> Artificial Sequence

<220>
<221> Primer_Bind
<223> Synthetic primer complementary to human genomic EGR-1 promoter
      sequence (Sakamoto et al., Oncogene 6:867-871 (1991)); includes a
      Xho I restriction site.

<400> 6
gcgctcgagg gatgacagcg atagaacccc gg                                   32

<210> 7
<211> 31
<212> DNA
<213> Artificial Sequence

<220>
<221> Primer_Bind
<223> Synthetic primer complementary to human genomic EGR-1 promoter
      sequence (Sakamoto et al., Oncogene 6:867-871 (1991)); includes a
      Hind III restriction site.

<400> 7
gcgaagcttc gcgactcccc ggatccgcct c                                    31

<210> 8
<211> 12
<212> DNA
<213> Homo sapiens

<400> 8
ggggactttc cc                                                         12

<210> 9
<211> 73
<212> DNA
<213> Artificial Sequence

<220>
<221> Primer_Bind
<223> Synthetic primer with 4 tandem copies of the NF-KB binding site
      (GGGGACTTTCCC), 18 nucleotides complementary to the 5' end of the
      SV40 early promoter sequence, and a XhoI restriction site.

<400> 9
gcggcctcga ggggactttc ccggggactt tccggggact ttccgggact ttccatcctg     60
ccatctcaat tag                                                        73

<210> 10
<211> 256
<212> DNA
<213> Artificial Sequence

<220>
<221> Protein_Bind
<223> Synthetic promoter for use in biological assays; includes NF-KB
      binding sites.

<400> 10
ctcgagggga ctttcccggg gactttccgg ggactttccg ggactttcca tctgccatct     60
caattagtca gcaaccatag tcccgcccct aactccgccc atcccgcccc taactccgcc    120
cagttccgcc cattctccgc cccatggctg actaattttt tttatttatg cagaggccga    180
ggccgcctcg gcctctgagc tattccagaa gtagtgagga ggcttttttg gaggcctagg    240
cttttgcaaa aagctt                                                    256

<210> 11
<211> 482
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (419)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (429)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (440)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (452)
<223> n equals a,t,g, or c

<400> 11
tcgacccacg cgtccgctgc cttctagttt ttagtctcag accagaccac cgggcgcgcc     60
ccgatgccga gcccgcagct tctggtgctc ttcggcagcc agacaggcac ggctcaggat    120
gtgtcggaga gactgggtcg cgaggcccgg cgccggcggc ttggctgccg ggtgcaggcc    180
ctggactcct acccggtggt gaatctgatt aacgagcccc tggtgatatt tgtttgtgca    240
actacaggcc aaggagaccc ccctgacaac atgaagaact tctggaggtt tatattccgg    300
aagaacctgc cctccactgc cctctgtcag atggatttgg ccgtcctggg gcttcgggga    360
tcctcatacg ccaatttcaa tttcgtgggc caagaagtgc accgaagggt aatggcagnt    420
ttggggggna gggcctcctn ggcccgtgtt gncttgggcg atgaaccagc atgaattggg    480
gg                                                                   482

<210> 12
<211> 623
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (171)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (538)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (549)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (568)
<223> n equals a,t,g, or c

<400> 12
aggtgagcct tttaagttca tttcacaaag cctggataaa gttgctgttt ttataatttg     60
aaaaagataa ttttgaaaac ttanattttt tttttccttt tgaacaaagt tgaccgctgt    120
tgccttgtct tctcacccag ggcatgtggg acgtgctctt ggctgtgaaa ntgtggggtg    180
tgtgcagaga gcctgggcct ggggttccca gaggagcatc ttggggaggc ctgcacagta    240
ggatcctgcc catgtgccct gagctgatgt gccagccgtg tgaaagtgct ctgacaccgt    300
gggccgtacg gagggcctcc agaggggatg ttgaaggcag gagacagctg tgccgggagc    360
ctctgcaggc cgtggagggc ccgtcctgtg acgtgtcttg ccctccctgc ttccacctct    420
ggtgtttgct tgcttcttgc gttcagggac cctttgcttg cagcgccatg ttcttgcatc    480
tttcttttgc tttttgtaag cttttgggat ctttcagttt tgatgggatt gggacaanca    540
tttatcctnc ttgttgggca cgggtttnaa cctaaaagga aagaaggaca gagatttttt    600
tcccacaaga agggttaaag ttt                                            623

<210> 13
<211> 556
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (408)
<223> n equals a,t,g, or c

<400> 13
ggcacgagct gggccgggcc accactgccc tcttgctcag tttccttggc cgccgcacca     60
tccaggcggg ttcccaggcc atggccggcc tcgccattct agccaacatg ctggtgccgc    120
aagatttgca gaccctgcgt gtggtctttg ctgtgctggg raagggatgt tttgggataa    180
gcctaacctg cctcaccatc tacaaggctg aactctttcc aacgccagtg cggatgacag    240
cagatggcat tctgcataca gtgggccggc tgggggctat gatgggtccc ctgatcctga    300
tgagccgcca agccctgccc ctgctgcctc ctctcctcta tggcgttatc tccattgctt    360
ccagcctggt tgtgctgttc ttcctcccgg agacccaggg acttccgntc cctgacacta    420
tccaggacct ggagagccag aaatcaacag cagcccaggg caaccggcaa gaggccttca    480
ctgtggaaag tacctcgctt ttagaaattg ttgccttgca tggagccctt tagtcaaaga    540
ttcctgggaa aggatt                                                    556

<210> 14
<211> 994
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (498)
<223> n equals a,t,g, or c

<400> 14
ggcacgnaga cagggtttca ccatgttggc caggctggtc ttgcactcct gacctcgtga     60
tccgcccgcc tcagcctcgc acagtgctgg gattacagat gtgagccacc gtgcccggcg    120
caaatgcatt tattgcatac aggacggtgc acctggactg tgctggccga atgcttctra    180
cactggagaa ggcggaaacc aaagcccacc ttccttcact cctgtctcca gttaccctcc    240
agatagacgt ttgggarggt tctcmrgcra ktagatktag raaktktgaw ktgctgttgt    300
gtttgttggc ramramactg tkgamtwrgg gcatggtttg tgcttggtkt kaarccyctt    360
cttccttccc agggaccctg atgccccaca accctgcggv accacagagc cgaccacaag    420
ctccagtctg tgtgggatcg atsatsrggs gytcaacaag cagattatgg agtacaaaag    480
ggggaaagtt aagggttngg ggccttgttt gcaggggcag gtggttgaat tgacaacgca    540
gtggaaaggg gagggagggg cccaaccccc gcttggagca ggacagttcc ttcaaggatt    600
acctttcagg gggaggagtt ggaagatgaa cttggaactt ggttggtgcc cccggagtac    660
gaatgttatg ccccggaaca cagaggagtt ggaggcagag agaggaggtg gcagaacaga    720
ggatggccac agctgcggag caagcaggga gtagatggag aggctctgcc catcccacat    780
ttgcagggaa aagcattggc acgcaacgca gcatgtggct tcattgaggc agttgatgga    840
gttaaaccat ctgctcttct gctacttcaa cattttctag cttttccatg tatctaaaca    900
caatttgcta cacaagtcac tgtttttttt tccatgcact gtgtgtaatt taaaaattaa    960
atggccatct tatcacaaaa aaaaaaaaaa aaaa                                994

<210> 15
<211> 431
<212> DNA
<213> Homo sapiens

<400> 15
ttttatatct tactatgttt ctcagcagtg tagggttttc tgtagtgatg atgtccatat     60
ggccatatct ccaaaagatt gatccgacag ctgatacaag ttttttgggc tgggttattg    120
cttcatatag tcttggccaa atggtagctt cacctatatt tggtttatgg tctaattata    180
gaccaagaaa agagcctctt attgtctcca tcttgatttc cgtggcagcc aactgcctct    240
atgcatatct ccacatccca gcttctcata ataaatacta catgctggtt gctcgtggat    300
tgttgggaat tggagcaggt aaggttgtat gtatatgttt ggttgtgtca tattcacatt    360
cattctgaca tttatggctc acttttaact ggtctcatcc ccttttaaac tcatatttca    420
cagttcaaca t                                                         431

<210> 16
<211> 630
<212> DNA
<213> Homo sapiens

<400> 16
tcctaatgcc tgtcacttcc caggacgctg gcagcagcag cagcccggag cccccgagcc     60
ctcggaggtt tgcgtgtcct tccccgcgat ctgattggat aaagtggggg ctcgacggtg    120
gccgacgtgg gacagtctgg ctgtggcagg ggtctcggaa accatgggtt attgcagtgg    180
caggtgcacg cttatcttta tctgtggcat gcaactggtt tgtgtgctgg agaggcaaat    240
atttgacttc cttggatatc agtgggcacc tatcctggca aattttgtac atattattat    300
cgtcattctt ggtttgtttg gaactattca atatagacct cgttacataa caggatatgc    360
tgtctggcta gtcctctggg ttacgtggaa tgtgtttgtt atctgcttct atttggaggc    420
tggggacctc tcaaaggaaa cagaccttat cckgactttt aatatatcaa tgcaccgatc    480
ttggtggakg gagaatggac caggatgtac ggtgactcat ggacacctgc cccagactgg    540
gccccagaag accatcgcta catcacggtc tcaggtgttt gctggatacc atacatagar    600
tggctcatag ttccctccag attgtcctcg                                     630

<210> 17
<211> 970
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (959)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (962)
<223> n equals a,t,g, or c

<400> 17
aattcggcac gagtgcaacc cttactcact tctgtgggag atgctataga ggccataatc     60
atyaccatgc atcaagaaga cttttctggg tcattatcca gctcaggaaa acctgatgtt    120
ccttgttctc tgtacatgaa ggagctacaa ggtttcattg ccagagttat gagtgactat    180
tttaaacact ttgaatgctt ggattttgtc tttgacaaca ctgaggctat tgcccaaaga    240
gctgttgaac tttttatccg ccatgccagt ctcataagac ctcttggtga aggtgggaaa    300
atgcgacttg ctgctgattt tgcacagatg gagttggctg tgggtccatt ctgtagacga    360
gtatctgatt taggaaagtc ctatcggatg ctgagatcat tcagacctct gctcttccag    420
gcaagtgaac atgtagccag tagtcctgca ttgggggatg tgattccgtt cagcatcatt    480
attcagtttt tgttcacgag agcacccgct gaactgaaat ctcctttcca gagggcagag    540
tggtcccaca cacgcttctc tcagtggctg gatgaccatc catctgaaaa ggacaggctc    600
ctcctcatca ggggagccct ggaagcttat gttcaatcag tgagaagtag agaaggcaaa    660
gaatttgcac cagtttatcc cataatggtt cagctgcttc aaaaggctat gtctgctctt    720
cagtaatgac atgaaatctt tgttcatctc cactttgtgc taacccattc atagttggca    780
gttaaacaca tactccaaaa gactgctact atctactatt ttaaggatgt aattgattgt    840
tcggtatttc ctatcgacgk ttatttaccc tttrgcactt atacttagca taaaaatgtt    900
gagttatcac caccaaaaaa aaaaaaaaaa aacccggggg gggccccgta ccccattgnc    960
cnttgggggg                                                           970

<210> 18
<211> 415
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (241)
<223> n equals a,t,g, or c

<400> 18
gtgtccagga acaggntcga tgacccttgt aggacactgg gggcgctgtt acctcctcac     60
cgagcgcagg tcgctgccct gtggtctaac agagcatgta ttcagacccg caccctcatc    120
tttggcggat gctgaagatg caagaaaagc cacctgcttg atgcttgctt ggcctggaga    180
tcgttctcct cttggtctgt gtcccgtggc ggcaggcctt gcagggaggg gggcgcaaca    240
ntggggagca tccgaatgga gtcccacttt ccaaccttgg ggctgctgca tcggcctccc    300
acatgtgacc tcccaggccc tgatgctgct tcttttgaag ggggtgaggc ctgatgggca    360
ggtcaagtcg gtccttcagg gaggggtcta cctcccttgc cccggggtgg tgccg         415

<210> 19
<211> 460
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (403)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (419)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (431)
<223> n equals a,t,g, or c

<400> 19
tcagcagctg aagtgctgcc cacctgtgtg agttgggtcc aggaaaccat gtctgccctt     60
ctgataaggg aagatgaatc tagagctggg tgaagatcta aattttaacc aaacccctgg    120
gcccaggaaa ataacaattg aaaatgtaca aggcagtgtt ttcaatatta aacttcccca    180
aggaaagcac aaactagtct ttttggaaag ggagaaagga ttaagccaca cagtattagt    240
ctttgaagca gtactggtct ctaggggctg gtgccaaaat gggagtccca tagtagttac    300
acttcgatgg gcctcatgta ctatattact gtgccaaatt gtatttaaac agtgggtggg    360
gggagttact ggggataagg aacttgttct aaaaagtttt acnaaaccca aaacaggtnc    420
tgtttaggtt nggtgccaaa gttaagtttt ttggccttac                          460

<210> 20
<211> 329
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (315)
<223> n equals a,t,g, or c

<400> 20
gcgggagaag agcggacagt ggtcggagat gtggcgaccg gtgcagctct gtcatttcca     60
ctctgctctg ctgcacagma ggcagaagcc ctggccgtcc cctgctgtgt tcttcaggag    120
aaacgtsagg ggccttcctc caaggttctc cagccccaca cccctgtgga ggaaggtgct    180
ctccaccgcg gtagtggggg cgcccctgct cctcggagcc ygctatgtca tggcagaggc    240
acgggagaag aggaggatgc ggctcgtggt ggatggcatg gggcgctttg gcaggtctct    300
gaagtcggcc tgcanatctc cctggacta                                      329

<210> 21
<211> 542
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (524)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (542)
<223> n equals a,t,g, or c

<400> 21
ggctttacgg ctgcgagaag acgacagaag ggggagaatc gaggcactcg ctggcgtacc     60
catgtatcga aatgagttca cggcctggta ccggcggatg tcggtggtct acgggatcgg    120
cacctggtct gtgttgggct cactgcttta ctatagccgg acaatggcga agtcgtcaga    180
ccaaaaggat ggctcagcaa gtgaagtacc cagtgaactc tctgaacgcc caaaaggatt    240
ttatgtggaa acagttgtca catataaaga agattttgtt ccaaatacag aaaagatcct    300
caactattgg aaatcatgga ctggtggccc tggtacagaa ccatgactgg ctgctgaatt    360
ctgaaaacca ggacttggtt caacatttaa atttgatagt tgccctgatt cccattttgg    420
gtttgtgaaa agtgtatgta tttaaatttg ctgtaaaaca taatcactaa taatatgcaa    480
taaatatttt cttgaaggga aaaaaaaaaa aaaaaaaaaa aatnccgggg gggggcccng    540
tn                                                                   542

<210> 22
<211> 431
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (427)
<223> n equals a,t,g, or c

<400> 22
ttcttatttt gatgctagga agcttattgg catttcatta tggattatat ttttatactg     60
taaagttcct tgctgtggtt ttttgcctta ttggttatgt tccatcagtt attctgttca    120
cttatattgc ttctttcacc tttaagaaaa ttttaaatac caaagaattt tggtcattta    180
tctattctgt ggcagcgttg gcttgtattg caatcactga aataactttc tttatgggat    240
acacaattgc aactattstt cattatgcct tttgtatcat cattccaatc tatccacttc    300
taggttgcct gatttctttc ataaagattt cttggragaa tgtrcgaaaa atgtgggaca    360
cctataatcc tgggataggc tttcagtagc tgttatatcg ccttacccgc cgtgttgtac    420
cgtgggnttt t                                                         431

<210> 23
<211> 599
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (499)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (580)
<223> n equals a,t,g, or c

<400> 23
ggcacgagga tttccagctc agcgatgccc ccaggtccct gggagagctg cttctgggtg     60
gggggcctca ttttgtggct cagcgttgga akttcagggg atgcacctcc taccccacag    120
ccaaagtgcg ctgacttcca gagcgccaac ctttttgaag gcaccgatct caaagtccag    180
tttctcctct ttgtcccttc gaatcctagc tgtgggcagc tagtagaagg aagcagtgac    240
ctccaaaact ctgggttcaa tgccactctg ggaaccaaac taattatcca tggattcagg    300
gttttaggaa caaagccttc ctggattgac acatttatta gaacccttct gcgtgcaacg    360
aatgctaatg tgattgccgt ggaytggatt tatgggtyta caggagtyta cttctcagct    420
gtgaaaaatg tgattaagtt gagcctcgag atctcccttt tcctcaataa actcctggtg    480
ctgggtgtgt cggaatccnc tatccacatc attggtgtta gctgggggcc cacgttgggg    540
gcatggtggg acagctttcg aaggcaagct gggacagatn aaaggcctga acccgctgg     599

<210> 24
<211> 590
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (556)
<223> n equals a,t,g, or c

<400> 24
actgagcgcg gccgccgagc ccagctccgc cgccgagcgc ctgtgccggc agwancacca     60
tggagcgccc ggataaggcg gcgctgaacg cactgcagcc tcctgagttc agaaatgaaa    120
gctcattagc atctacactg aagacgctcc tgttcttcac agctttaatg atcactgttc    180
ctattgggtt atatttcaca actaaatctt acatatttga aggcgccctt gggatgtcca    240
atagggacag ctatttttac gctgctattg ttgcagtggt cgccgtccat gtggtgctgg    300
ccctctttgt gtatgtggcc tggaatgaag gctcacgaca gtggcgtgaa ggcaaacagg    360
attaaagtga acatcacctt tttatagcat taaattcatt ttttaaaatg ataaatgctg    420
gagggggcca tctgatttga ataaagttga aagaacatgt taaagtcagt cttaaggagt    480
cacgtttgag tatgtaaatt ttgatccttc caatatgktg gttgtaaatc agtttaactg    540
tatgaatcyg attgcnatga gaattggaaa gtagtaccaa gaatatgtta               590

<210> 25
<211> 424
<212> DNA
<213> Homo sapiens

<400> 25
cccacgcgtc cgggaaagct ggctgcccgc cagagccgtc gttgcaaatg gcaaatacta     60
atttcctctc caccttatcc cctgaacact gcagaccttt ggcgggggaa tgcatgaaca    120
agctcaaatg cggcgctgct gaagcagaga taatgaatct ccccgagcgc gtggggacyt    180
tttccgctat cccggcttta gggggcatct cattacctcc aggggtcatc gtcatgacag    240
cccttcactc ccccgcagca gccttcagca gccgtyamag acagtgcgtt tcaaattgcc    300
aatctggcag aytgcccgca gawtcattcc tcctcctcct cgtcctcctc agggggagct    360
tggsggasca accccagcca agaagaagag gaaaaggtkt ggggtcttcg tgccctgcaa    420
gagg                                                                 424

<210> 26
<211> 642
<212> DNA
<213> Homo sapiens

<400> 26
ctcagaggat caaaaagcct tcagtgttga acatacaagc tgcaatgagg aagaaaattt     60
cgcaaatatg aaaaagaagg ccaaaatagg cattcatcac aaaaatagtc cccccaaagt    120
cactgttcca actagtggaa atactataga gtctcctctt catgaaaaca tctctaattc    180
aacatcattt aaagatgaga aaatcatgga gactgatagt gaaccagagg aaggtgaaat    240
tacagactct cagactgagg atagttatga cgargccatt accagtgaag gcaatgtaac    300
tgcagaagat agtgaggatg aagatgaaga caaaatctgg cccccatgta ttagagtaat    360
tgtcattaga tcacctgtgt tgcagatagg atcactcttt atcattactg ctgtaaaccc    420
tgctacaatt ggaagagaaa aggatatgga acatactctc cgaatccctg aagttggtgt    480
cagtaagttt catgcagaaa tttattttga ccatgactta caaagttatg tccttgtgga    540
tcaaggcagt caaaatggca caattgttaa tgggaaaaca gattcttcag ccgaaaacta    600
aatgtgacct tacgtacttg agcatggaga tgaagtcaaa at                       642

<210> 27
<211> 319
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (201)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (315)
<223> n equals a,t,g, or c

<400> 27
caaggacagg catgattgag ggccggcagg atctaggagc ttccatcagg cctttgacaa     60
agagccctcg ctcgggggtc accgcgtgtt caggaggggc tgagttaccg cttctcatct    120
tccacttgca ccccgacaga gtggtattcc cgcagaccgc ggctctccgt gtcagaatct    180
gtggccgttt ccacctaatt naacagagaa cgtcttattt tagaactgga aacatggggc    240
ctgggcaagg ggactatttt gttggttgtt gtgggatttt gctgttaatt aaatttacgg    300
gatttgtttt aattnaatg                                                 319

<210> 28
<211> 376
<212> DNA
<213> Homo sapiens

<400> 28
ggcacgagga aagaagtaaa aatgtttgct tcctcttggc tttcattctt atatgcaggc     60
agaacctgaa caaatacttg ggagtcactg gagggatctt actgtggtca ccttcctcat    120
ttcctcttct tccttctttc cttctcttta tccttctctt ttctctcaaa gtcacttaga    180
gatgctggaa tcacacatgc taatattagt cctggaaaga aattataggg attttscttc    240
tcccttcctt ctccctgggg ctgttgttcc ccttttcctc tatatcccca ctgttagaaa    300
aaatggggtc actgagaaat ggggcactac atttgggggt agcaggataa ggacggrtat    360
tttagtagaa tatcct                                                    376

<210> 29
<211> 482
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (372)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (464)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (468)
<223> n equals a,t,g, or c

<400> 29
atggaagtgc tatctggaga gcagaacatg atgacaaagg ttcgagaaaa caactacacc     60
tatgaatttg atttttcaaa agtctattgg aatcctcgtc tgtctacaga acacagccgt    120
atcacagaac ttctcaaacc tggggatgtc ctatttratg tttttgctgg ggttgggccc    180
tttgccattc cagtagcaaa gaaaaactgc actgtatttg ccaatgatct caatcctgaa    240
tctcataaat ggctgttgta caactgtaaa ttaaataaag tggaccaaaa ggtgaaagtc    300
ttcaacttgg gatgggaaag acttcctcca aggaccagtc aaagaagagt taatgcagct    360
gctgggtctg tncaaaagaa agaaaaccct ctgtgcacgt wgtcatgact tgccagcaaa    420
gctataggtt tcttagtgct tccaggggct ttaaatgggc gccngcancg tagtccttcc    480
ct                                                                   482

<210> 30
<211> 986
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<400> 30
ggcacgactn cactatnagg gcgaattggg taccggttta ccagagaaca aaaacttcag     60
taacgggatg cgcaaatgaa tttcatacag aattatcgca atccctacta caaatatcag    120
gccacagaga aaaccaagcc agttggaggt gatgtgcggt gtaatgtatg cgccgaaaaa    180
cagcgttaac gggtggtgaa ccagatagat aaacagcgat gcgttaacaa aataagtcac    240
ccgcgctgac tggaagttaa gcaaacggtg gccaaaggag aagaccacat tcaccatcca    300
cagaccgagg accatggtga tcaccgactc ggtttcgtac atccaggcat cgccactgcc    360
atagcgctgg ttgagtaaat aagcgacaaa cgccaatgct gctgcaaggg tacagccacg    420
agacggcgtg gtaaacaagg ctttaagatg agggaaaatg aaagccagtg cgccgaggat    480
aaagaacggc aaataaaaca gcgtttgcat gacataaatt gaacatgcca ttactcagaa    540
tgggcggata cacaataaaa atcgktcttc ttattmccgc wtaaccgatg ccgaggcata    600
aaaaaatcac cgatagtttt accatcgagr attttttatt cgttttatca gaattttcta    660
aattatttct gatgcgctta aatatccata gcacagcgtc gtcatgacca ctaacaccag    720
taaaaaccac aggtgtgata ttaattccca ggccaacgta ttatatttgt catacaatga    780
cagcccaggc caactttccg cttttccttt gacatattgc agcataataa attgcggtaa    840
tgtcagtagg gggatggctg ttaacatcgg gatacctaca cgttcgacac gtactttcca    900
ccattttttc aagggatagc gtaaaaaaag catgtaggaa aagtagcccg ggggatccac    960
tagttctaga gcggccgcca ccgacg                                         986

<210> 31
<211> 671
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (654)
<223> n equals a,t,g, or c

<400> 31
ggccatcatc tccggcatga acatgagccc tgtctccagg ctgaagaaga cctggggcca     60
aagtgaggac ggccaagttt ttcatcctcg agcaccagat ggacccaacg ggaatttctg    120
caactacagg acagccctgc gcggggcggc ccaccgctcc ctgacggccc acagcagccg    180
agagaagatt gtcattcctt tcttcagcct gctcatcaaa gacatctayt tcctgaatga    240
gggytgcgcc aaccgccttc ccaatggaca cgtcaayttt gagaawttcc tggagytggc    300
caagcaggtg ggggagttca tcacctggaa acaagtggag tgtcccttcg agcaagacgc    360
cagcatcacc cactaactgt acaccgcccc catcttcagt gaggatggtc tttatttggc    420
ttcttatgaa agtgagagcc cagagaacca aacagaaaaa gaaagatgga aagctctaag    480
atcttctatt ttggggaaga catgaaagcs ctgagctgag ggacgaggaa gagctggagc    540
ccgcagaagc cgtccacagc cctgcctcag tggcccagtg ggcagaggcc agggaagtgc    600
ctcactattt tgcaaatgcc gaccctgtgg cctgctgccc gccccccccc cccnaaagtg    660
gccataaggg g                                                         671

<210> 32
<211> 476
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<400> 32
aattggcacg agctctactc cagattcttc tccatccaca ctgtctcctt tctccaggga     60
gctcacaggc tcttccaggc cacccaaatg gttcagtcgc tgaaaagcat ggaaggaatt    120
caggtggaac ctgcaagaaa gaggacaaaa ggcaggactt acttttgccc atctgtctcc    180
ctgaatgggg ccagcaatgg tgagtctctg aggcatggga agagttggga ttctcttctg    240
gttttgatcc cagcaaccac aatagtagct accatcaatc aagtgtctac gtgccataca    300
gtctacatac attattccct tttgccctcc aacagccctg tatgtgctta tttccctatt    360
ttaccagaag ggaacttgag gstcagaagg gttaagtgtc tgggccaagg tcaaaaagtt    420
cytatggggg acacagggta aaaaaccagt ttgccctatg gggttggggt kagggn        476

<210> 33
<211> 652
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (444)
<223> n equals a,t,g, or c

<400> 33
cgacgccccg gccgcccgcc cgtccgcttg ccaaccatgg agctggagga cggtgtggtg     60
tatcacggag gagcccggcg gctccggggc cgtgatgtcg gagcgggtgt ccgcctggcc    120
ggctccatct accgcgagtt cgagcggctt atcgggcgct atgacgagga ggtggtcaaa    180
gagctgatgc cgytggtggt ggctgtgctg gagwacctgg actcggtgtt cgcgcaggac    240
caggagcacc aggtggagct ggagctgctg cgggacgaca acgagcagct catcacccag    300
tacgagcggg agaaggcgct gcgcaagcac gctgaggaga aattcattga atttgaagac    360
tctcaagaac aggaaaaaaa ggacttacag acccgagtgg aatctttaga atctcaaaca    420
agacaacttg agctgaaagc gwanaaacta tgctgaccag attagcagac ttgaagaaag    480
agaagcagaa ctgaagaagg aatataatgc attacatcaa agacacactt gagatgatcc    540
ataattatat gggaacattt agaaagaaca aaacttccat ccagctcttc agggagtggt    600
tcaactagga ttccacagct ccttagttag gatttggaaa agaacgccct at            652

<210> 34
<211> 822
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (361)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (769)
<223> n equals a,t,g, or c

<400> 34
ccagacatga ctctccctgg aatctcccca ccacccgaga aacagaaacg taagaagaag     60
aaaatgccag aratcttgaa aaacggagct ggatgagtgg gctgcggcat gaatgccgag    120
tttgaagctg ctgagcagtt tgatctcctg gttgaatgag atgcagtggg gggtgcacct    180
ggccagactc tccctcctgt cctgtacata gccacctccc tgtggagagg acacttaggg    240
tcccctcccc tggtcttgtt acctgtgtgt gtgctggtgc tgcgcatgag gactgtctgc    300
ctttgagggc ttgggcagca gcggcagcca tcttggtttt aggaaatggg gccgcctggc    360
nagccactca ctggtgtcct gtctcttgtc gtcctgtcct tcctatctcc ccaaagtacc    420
atagccagtt tccagatggg ccacagactg gggaggagaa tcagtggccc agccagaagt    480
taaagggctg agggttgagg tgagaggcac ctctgctctt gttgggaggg gtggctgctt    540
ggaaataggc ccaggggctc tgccagcctc ggcctctccc tcctgagttg ccttctgttg    600
gtggctttct tcttgaaccc acctgtgtaa agaggttttm agttccgtgg gtttcccctt    660
tgaattctgt aaatagtccc agagagaatt cgtgggctga gggcaattct gtcttggagg    720
aagaagctgg acattcagcc tgtggagtct raggttttga aggatgtang ggagccttag    780
ttgggtctca raccwtaagt gtgtactaca cagaagctgt gt                       822

<210> 35
<211> 1042
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (959)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (980)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1006)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1023)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1033)
<223> n equals a,t,g, or c

<400> 35
tggtaaaacc tgacgcgctg gtggaaatcg ccacaattgc gcatatcgcc aagtgaggcc     60
gcgatgaaac tttcactctc acctccccct tatgctgatg cgcccgtagt ggtgttgatt    120
tcgggtcttg ggggtagcgg cagttactgg ttaccgcaac tggcggtgct ggagcaggag    180
tatcaggtag tctgttacga ccagcgcggc accggcaata atcccgacac gctggcagaa    240
gattacagta tcgcccagat ggcagcggaa ctgcatcagg cgctggtagc cgcagggatt    300
gagcattacg cagtggtcgg ccatgcgctc ggtgcgctgg tgggaatgsa gctggcgctg    360
gattatcccg cgtcggtaac tgtgctgatc agcgttaacg gctggctacg aataaacgcc    420
catacgcgcc gctgttttca ggttcgcgaa cgattactgt atagcggcgg cgcgcargca    480
tgggtggaag cgcascgttg ttcctctatc ccgccgactg gatggcggcc cgcgcacctc    540
gcctggrggc agaagacgcg ctggcactgg cgcattttca gggcaaaaat aatttactgc    600
gtcgacttaa cgccctcaaa cgcgctgact ttagtcacca tgcggatygc atccgctgcc    660
cggtgcaaat catctgcgcc agtgatgatc tgctggtgcc aacagcatgt tccagtgaac    720
ttcatgccgc cctgcccgat agccagaaaa tggtgatgcc ctatggcgga cacgctgcaa    780
cgtgaccgat cccgaaacgt ttaatgctct gttactcaac gggcttgcca gcctgttaca    840
tcaccgtgaa gccgccctgt taaggaattg ctatgaacga agccgttagc ccaggtgcgg    900
ttagcaccct gtttcaacgt tgcccgcatt cacaacggtt ggcgggagac aaccttcanc    960
gatgagacgt taagggaggn tttttgccct gatggaatgg gggccnacat cagttaactg   1020
ttntccggaa ggntcgtgtt ta                                            1042

<210> 36
<211> 875
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (872)
<223> n equals a,t,g, or c

<400> 36
ggcacagcgc gaggctgggt cccggcccag gagaaggaag tcgctgaagg cagtggccat     60
gctggncgtg gaaatgggag gcggttgcag rgggtctatg gggcccggtc ctggatactc    120
ggcaggaagc cgtgtctgca gaggctcctc cctgcctcag gtggccccgt tcaaccccag    180
ccgtgcccat ctcctgccac cgcctgtcgg tgggggttta aattcggtgt ggctttctgg    240
ggtgcagctc agcacccccc cttatgcaga ctgggagggg gtcgggcagt cccctcagcc    300
acgaggaccc tggatgggtt ctagttcact tgggaccgtg gggcctggct gcgtactgag    360
tgggtgcccc acagtcaagg ccaacggggg ctccccctgc tctgagatgt tgggagaaag    420
gcggcttctg gaaccttccg tgggacccgt aagtggctgt ccagaaaggc gggagggtgg    480
gcacggggca cggggggcag ctggggtcgt cgttaagggt cacgcatccg tacagttgaa    540
tttcctttct cttatcatgt tttacccacc ttgtcccttt tttccccaat tgtgcttttg    600
catttttttc cttggcaaat gtaaactcag cctttcattc atgacgtgtg aaatttcagt    660
ttctctggag tttgtcagac ggcgtgggaa ccacgcctga aactcaggta ataggaggaa    720
aaaaaaaaaa cttaaaaaaa tttttaaaaa acataaaact actctctacc tctgctggsc    780
cagcctgtct cgccctggcc gcggcagggt ggcctgtaac aatttcagtt ttcgcagaac    840
attcaggtat taaaaggaaa aaaaaaaaaa anggg                               875

<210> 37
<211> 413
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (342)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (389)
<223> n equals a,t,g, or c

<400> 37
gtgacggggg cttccagccc actgaacacc cctgtcctgc catagcccca gaggtaccac     60
cttgggctct gccagtgctg cttcaacacc tccagatggg aggagaggga cctttccttc    120
cagttctaac ccccacatca gtcaagggaa ccctgtacaa aatgctgaga aagccaaaga    180
aagtcagagt gcaggcagct tcttgtgact tactgcgggg gctccttgtg tctcccctcc    240
tcctgcctgt tagacttctc cttgctggct gggcccacgc gtggatgcac gggtgcggag    300
gatgggaacc caggatcayt cagcaaagtg cttcttgtca gnttctggca aaggggagaa    360
atcaagggtc aaccaaaagt tttaaatgna aattggagga ctcctaactt tat           413

<210> 38
<211> 417
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (387)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (408)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (410)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (412)
<223> n equals a,t,g, or c

<400> 38
tggaagtgac tcatccaaac tccatgccag ctgtcaacat tcagtatgaa gtcatcgata     60
atgcctgtgt tctttttgcc gtctctgttc ttatgtttat aatcagttca atgctggttt    120
atggagcaat ttcttatcaa gtgggttggc tgattccatt cttctgttac cgactttttg    180
acttcgtcct cagttgcctg gttgctatta gttctctcac ctatttgcca agaatcaaag    240
aatatctgga tcaactacct gattttccct acaaaggatg gacctcctgg gccttgggac    300
tccagctgcc tcctgttcca ttgttcttgt gttcttgcct attcatcatt ttaaggstta    360
tctaataacg tgtttggaac tgctatnaaa tacatcaaca accgaaangn gncggga       417

<210> 39
<211> 329
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (193)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (309)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (324)
<223> n equals a,t,g, or c

<400> 39
ggcacgagcc caaatcaatt atgacaatga tgattgtctt tctgtctctc tctctctctc     60
tatatatata cacacacata tatacacaca tatacacaca catatatata cacatatata    120
tatacacata catatatata tacacacaca cacatacata tatttgtttt gttttgcttt    180
tgttttgttt ttntgttttg agacaaggtc ttgttttgtt tcccagggct gggagtgcag    240
tgacacagtc atggattcac tggcaaccct ggacctcctg ggtcttcaag ctagcctccc    300
aacttcagnc tttcccagta gctngggga                                      329

<210> 40
<211> 1326
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (912)
<223> n equals a,t,g, or c

<400> 40
cccccctcga gttttttttt tttttttttt tttttttttt tttttttttt tacagtaaaa     60
atatttattg gtataaaaat gcccatgata cacttttatg taaatgaaat atgtttcaaa    120
atagcacgta aagcagggta ctaatttgtt aaggacatcc acacacatgt ccacacaagc    180
atctatacta aaagaaggta cacatgcatg ctgctgtatg aacggtgatc ctctgcctat    240
ggtgaggtta ttacaggrta tatttaattt actatgtctt gattttctaa gtgtcaaaat    300
ttttttcaca taaatattta ttttcttggt acatagaaat aattacatta aaaataataa    360
agagtctatg aagaaacatg actaactata ctacgaactc agaaccttaa aataagtaat    420
ccagttacat tttttattga tacatwatct tgcattcttc agacctatgg ccctcctggg    480
catgtagact ttctcttgca tagggccaga gcatcaggac actgttctct gcagatgagt    540
gaacacagtg tgtcacccag actcggctat actggagtaa gtaagttact accaagagat    600
gctattctgc actttaaagg ctttaaatga gtacatggaa tacactattg ggttggtgct    660
agaggcaagt gctggatgaa gaggargtgt gctttatgcc acaatcaaca gcaaagcaac    720
tgtgcaccaa aatcatgtgt tttcaattat cttcattcat tcattcattc atccatcaaa    780
acacctacag cgtgtctgtt gagttccacc cactatgtgc caggtactgt gtgaggcawt    840
agagcagaca tgaggtatat agattatggt ccctgtcctt gtcaagaaat tgtctgtgag    900
ggagtcagaa antacagaac ggtgagtgct ctggcgacca gagaagcaag aaggcttgtc    960
ctatgcagaa aatgtgttct tagatgaggc gatgtttgaa acatgtctga aaggaaccca   1020
cccatcagag aggaagagga agggctctct cggcaagaga aaggactcac acatatcacg   1080
tatatccaaa tgatgaggaa aggcatggga catgagtgga gcaacaggta gtggtgggag   1140
aggaagtgaa aggtaatttg ggatttgacc atagtgtctt gtaatgtagt atctcccaac   1200
tcttcacaat aggacacaca tagaatagaa accatctatt tgtacagcac actgggtaaa   1260
tgaagggact gcatgcaact aagtgactgt tcatttgctc agctccatta gagactgagg   1320
ggatcc                                                              1326

<210> 41
<211> 1219
<212> DNA
<213> Homo sapiens

<400> 41
ggcacgagga gccttgggcc cctctggcct cagccggatt tcccagccaa acgcagagag     60
agatgccctg gaccatcttg ctctttgcag ctggctcctt ggcgatccca gcaccatcca    120
tccggctggt gcccccgtac ccaagcagcc aagaggaccc catccacatc gcatgcatgg    180
cccctgggaa cttcccgggg gcgaatttca cactgtatcg aggggggcag gtggtccagc    240
tcctgcaggc ccccacggac cagcgcgggg tgacatttaa cctgagcggc ggcagcagca    300
aggctccagg gggacccttc cactgccaat atggagtgtt aggtgagctc aaccagtccc    360
agctgtcaga cctcagcgag cccgtgaacg tctccttccc atgcccactt ggatcttggt    420
gctctccctg agcctggctg gtgccctctt cctccttgct gggctggtgg ctgttgccct    480
ggtggtcaga aaagttaaac tcagaaattt acagaagaaa agagatcgag aatcctgctg    540
ggcccagatt aacttcgaca gcacagacat gtccttcgat aactccctgt ttaccgtctc    600
cgcgaaaacg atgccagaag aagacccggc caccttggat gatcactcag gcaccactgc    660
cacccccagc aactccagga cccggaagag gcccacttcc acgtcctcct cgcctgagac    720
ccccgaattc agcacttttc cgggcctgcc agtgaggctg aggactgggg gacccctctg    780
tctccaggca ttcgggggcc tgaggtccct ccagctactt ctgggggggc tctgtcagcc    840
actttctcag ggaattggac agaggaaagg aaggggaacc ctggccttgg gattttcatc    900
acagaggagt gggagagggg acacaggcat gggcctggca ctatacagac aacaggaagt    960
tcccctctcg acttcggctc ctcaggacca ccagagaagg agatgtcagg accccttctt   1020
gtcccccagc tgggccataa gacgtcccag gtctctgcac acccgtggaa ttcctccctt   1080
ccccagtggg tttttgagca tagggtgccc ttgggtgtgt tgtgtgtctg cctgctggct   1140
tgcttaagtt attaattata acacgggtca aggtgaaaaa aaaaaaaaaa aaaaaaaaaa   1200
aaaaaaaaaa aaaaaaaaa                                                1219

<210> 42
<211> 1154
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1136)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1139)
<223> n equals a,t,g, or c

<400> 42
tcgacccacg cgtccgctgg cgggagtctg agaagttgga taaggcgggc aggcggggaa     60
gagggaaagg agcgaggagc ccggcggact ggcgccccta gcggtggttc taacgcgtgc    120
actgggcaat gctggctatc ggcttcctct ccctgccagt ttcccagcag tcttgcccat    180
tggggagcag ccccccgaag gcagtggcaa catcaagcag aggtacagat tgcccgaaag    240
cttcagtgca ttgcagacca gttccaccgg cttcatgtgc agcaacacca gcagaaccaa    300
aatcgtgtgt ggtggcagat cctcctcttc ctgcacaacc ttgctttgaa tggagaagag    360
aacaggaacg gggcaggccc taggtgaggg tgggctgccc tcttcacatg gggcaccagg    420
aacaccgtct ggaacaggaa ggacatcggg caggactgac actgtgtctt gtgaaattgt    480
ttttttgttg ttattttgtg ttwtaatttt ttttaatttc tctctgagtg tacatacaac    540
atactcaagc gggaccttct ttctctgtca ggcccttgac ctggaatggg ggcctgtgtc    600
aaacactgtt gaaggagagg ctgatgtgtc tgtgatggtg agaattccca agggctctga    660
caagtagatt cttcgactga ggaatctacc agttgtcgaa gatgatccgt tagtgatgtt    720
ctctgggaag tggactgtgg tttttccaga ggaactcagt taagaaatcg agagtggatt    780
agactcccag ttccaccaaa cctatgarcc ttccactgtg gatgggggcc gtgatcctga    840
tggtcacatt gctttaaccc agcagggctt cggccagggg ctttccactt gaggatagca    900
gcttcactag gctggccggc cagctccaca tctgactggg ttcttacttc tcagccagta    960
cctgccccat gggctcaagg attcctggcc agctcctgcc acctccagca gacctcargg   1020
agggttgggt ttctctaaag accctcaaac atgtcgcaaa atgaarcaaa cttctggcta   1080
wgsctcaaaa ctgamttggt cccacttgga ggcccaagat tggtcctgaa gttcanaanc   1140
actgccacca ctgg                                                     1154

<210> 43
<211> 1029
<212> DNA
<213> Homo sapiens

<400> 43
taccgctcgc cctgacatcc ggtaccttac aggcctggat gacggtcgag aatatcgatc     60
tcaaaaccat tggtttcttc tctctggtag gccaggctta cgtttttaaa ttcctctggt    120
caccgctgat ggaccgctac acgcctccat tttttgggcg gcggcgcggt tggctgctcg    180
ccacgcaaat cctgttatta gtcgccattg cggcgatggg ttttctcgaa ccaggcaccc    240
aactccgctg gatggcggcg ctggcagtgg tgatcgcttt ttgctctgct tcccaggrat    300
atagtcttcg atgcgtggaa aaccgatgtg cttccggcag aagaacgtgg tgcgggcgcg    360
gcaatcagcg tgctgggtta ccgtttaggg atgctggttt ccggcggcct agccctgtgg    420
ctggcagata aatggctggg ctggcagggc atgtactggt taatggcggc actgttgatc    480
ccctgtatta atcgcgacgt tgcttgcacc agaaccaacc gacaccattc ctgtgcccaa    540
aacgctggaa caagcggttg ttgcacctct gcgagatttc tttggtcgca ataatgcctg    600
gcttattttg cttcttatcg tgctgtataa gctgggcgac gcattcgcca tgagcctgac    660
aaccacgttt ttgattcgcg gcgtcgggtt tgatgcgggt gaagtaggcg tggttaacaa    720
aacgcttggc ttactagcga ccattgttgg cgcattgtac ggtgggattt tgatgcagcg    780
cctgtcactg ttccgggcac tgctgatttt cggcatttta caaggtgcgt ctaacgccgg    840
ttactggctg ctgtcgatta ctgataagca tctctacagc atgggcgcag ccgtcttttt    900
cgaaaacctc tgtggcggga tgggcacatc agcctttgtc gcgctgttaa tgacgctatg    960
taataagtca ttttccgcta ctcaatttgc cctgctctca gcgctttctg ctgtagggcg   1020
agtttatgt                                                           1029

<210> 44
<211> 700
<212> DNA
<213> Homo sapiens

<400> 44
atggaagttt gcagaaattg ttcagctgta ttatgctgtc gtatggctcc actgcagaaa     60
gcaaaagtaa taagactaat aaaaatatca cctgcagaaa cctataacat tggctgttgg    120
tgatggtgct aatgacgtaa gcatgataca agaagcccat gttggcatag gaatcatggg    180
taaagaagga agacaggctg caagaaacag tgactatgca atagccagat ttaagttcct    240
ctccaaattg ctttttgttc atggtccatt ttattatatt agaatagcta cccttgtaca    300
gtattttttt tataagaatg tgtgctttat cacaccccag tttttatatc agttctactg    360
tttgttttct cagcaaacat tgtatgacag cgtgtacctg actttataca atatttgttt    420
tacttcccta cctattctga tatatagtct tttggaacag catgtagacc ctcatgtgtt    480
acaaaataag cccacccttt atcgagacat tagtaaaaac cgcctcttaa gtattaaaac    540
atttctttat tggaccatcc tgggcttcag tcatgccttt attttctttt ttggatccta    600
tttactaata kggaaagata catctctgct tggaaatggc cagatgtttg ggaaactgga    660
catttggcac tttggtcttc acagtcatgg ttattacagt                          700

<210> 45
<211> 1246
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (42)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1207)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1225)
<223> n equals a,t,g, or c

<400> 45
tatagaagtg cgcatgcagt acaggtcagg gaattngggg tngacccacg cgtcmggtct     60
cmtgctgctt agggactcta ctagcctttt acttaaagcc agttctgata tgtttgtttt    120
tgtaatcmaa atatgttccm aaaagattga tctatsaggg gacagtttga gtataatgca    180
cattttgtgt ttgcttagca ggattttgtt cacaagaaac actagtaaac aaagaaaact    240
gtacctgcat gagccggagc atgtagaaat gcacacaatg tacacaggca atgccgtgag    300
catctcccag tcactcccat ccacagcctg tgtagtgagc ccgtcacatc tggtgtgaga    360
ctttccatcg aatttcgtac aaccttcttt cctccacttc acaatgggct cacaagctgc    420
aaacttcagt tcattttcaa gatcaagggc catctttatt agtattccat ctcttaatat    480
gtgtgaaatt atgttactat ttttatgagg tttctacatt ttaggtaaaa agtgtccgtg    540
ataaagtttg tgagtgttgt gccccaaccc catttttctt cctataaacc ctgctgttcc    600
tacgacataa tcacacatag ttacaatgat attttagaaa ctcttatgtc acatcatagc    660
aaaattgatt atgcataatc tcatttagtt tagcttaatt gagacaggtg ggtattatgt    720
cagtatttat tatgtgggtg ttatttktyc caatttgcag ctgtaggaat tgaaggtcag    780
gttgatccag gtcaccatct actatgtgta gtgctgaaat taaaacccag gtcastctgc    840
ttcctaagtg tggctattag ccatggtgct ttgaggatgg aagaaatcta cttccttaat    900
actcaggaga ttcacagagt caggaccaaa tactcacaga gcatttgaag atttccagcc    960
aacattttca garcctggct actatccarg ggaatttaaa gtgtgacgca gcccaccaaa   1020
gttgattgca tcttagagaa tggaatccaa gtctcccacc aggaaaaata caggcattca   1080
ttagttcctt cccctaaaag gttggacatt gatccaggca ctatagagca cctgggatac   1140
aacactgagc aaagcggtct tcctccctgc ctcactctgc ttagaggacc aattcctggg   1200
aatgganggg gttgcacaca ttaangaaag gactcttcac agcaaa                  1246

<210> 46
<211> 813
<212> DNA
<213> Homo sapiens

<400> 46
caagggctag atccaagggg tcatacaatg tcattgagac ctacctctgt ggtaccactt     60
ctgagatgac ttcaggcata acagacaggc tttctccaag gtgaagaccc ccaggttcag    120
acggcccttg ggcttaccag ccctattggg gcactccttt tttttccact caaaagcact    180
ctccttggtt ctgtttgcgt cgtgagccga tccctgagcc aaacactgtt tccagggggt    240
gaggtaccta gactagaatc ctgggcctgg gtccctcaca tgtggcacag agggaatggc    300
artgttacca ggtttggagc aagagtggag acagttcctg aaaacaaaag ttgccggaca    360
ggaaaaaata ataarsaccc cacaaaaaat catgcaaaga aaacaccggt tagaagacag    420
cagaatagac ttgtcctcaa ggagggagat aagagaaagc atgaaggaag agctgtcagg    480
tacagggata aggaaccaaa aactcagttg tttaactctc tgtgagtcca ccttgttaat    540
tctgcttcat ctttccatta atttttattt ttcctttatt aaaaattcta ctttgatggt    600
agtgcttttg gagccaatta ttcctcacag cctctggatg agagttggcc aaggtaagca    660
agacatactt taaaagatat gatgggcatg tgttattttt agataatttc actttatcca    720
ctttgaatgt tgtttagaaa ttctaatata aagcatagaa tcctgtttct cttataacat    780
ttaatttcag tgggaggatc acttgagacc agg                                 813

<210> 47
<211> 485
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (363)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (395)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (441)
<223> n equals a,t,g, or c

<400> 47
ggcacgaggc aaaacactgt ctctctaatt tcttaggtaa cctgccatct gcattcaaat     60
ttacctcact tactgatgag tttcttttgg ccatgaagag gtcttgtgtc tcctgtggtt    120
tggaaccttg ggagtctggg tgggaaagag taggtgaaat cacccatccc tgggcctggg    180
gggaattccc agaaatggtg ctagccatca ggatgtataa gtatgtgttc acgcatgcct    240
tcatatcctt gagcaccagt agtgatggaa gtgcctgtgt gctgtcagct ggggcgggtg    300
cagggtgtcc cctcgcttgc cagttcgcct tgttctggac tggtccattg gccctttgcc    360
ttnaggcagg aagggcagaa agagtgctct ctgtnaaaga ggggttgggc cccgtgccct    420
caantcaagc ctgccatgga nttgtggttt tcctcctagg tctgttgaca ttgtgaactg    480
tgccc                                                                485

<210> 48
<211> 429
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (236)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (414)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (425)
<223> n equals a,t,g, or c

<400> 48
ggcagcgtaa gaacatgcca tggagtgtgg ttgaggcttc cacacagcta ggcccatcca     60
ccaaggtcct gcatggcctc tacaacaaag tcagccaatt cccagagctc accagtcata    120
ccatgcgctt caacgccttc atcctcggcc tgctcaacat ccggtccctg gagttctggt    180
ttaatcacct ctataaccac gaagacatca tccagaccca ctaccagccc tggggnttcc    240
tgagtgcagc tcataccgtg tgtcccggcc tctttgaaga gctgctgctg ctgytacagc    300
ccctggccct gcttgccctt cagcctcgay ttgctgttcc agcaccggyt gytgcaaagt    360
gkggcagcag cagcggcagm acaaggaact gttgcggggt tgttcccagg gacntgctgg    420
ttgtnctgt                                                            429

<210> 49
<211> 439
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (356)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (361)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (377)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (380)
<223> n equals a,t,g, or c

<400> 49
cccacgcgtc cggaaacagg agagtgaagt ggaaatagcc tggcccgcgt gacttaaacc     60
ggcccggaga tgtgcgggta cgaatggagc cgccttgggg tcgggatagg acccagagtg    120
gcttctcagt caaaggcctt cagaagcaga gggagcacct tgagtgacct tacctgggcc    180
gcgaaagaca agaaaccttt ggcacaggaa gaggaactga tctctggaag ccaccagggc    240
gggtggaaag tcagggtttc aaggttattt tggaatttag gtgctgtggg ccttgtacgg    300
tggctcatgc ttgtcatccc agtgctttgg gaggccgagg caggaggttc gctttnagcc    360
naggagtttc cagagcntcn tgggcaacat agtgagattt ttgtttacaa aaaaaaaaaa    420
aaaaaaaaaa aaaaggggg                                                 439

<210> 50
<211> 701
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (583)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (674)
<223> n equals a,t,g, or c

<400> 50
ntatgcacag tctgaatgta taccaggagt gtgagagaca catgcccact tcatgcaact     60
cctaaactca aagtctaaat cagatatttt tattaacaat gacaacttgt tgccaactcc    120
ctgtttctaa tsaccaaaga cccagggtac ctaaaaggac tttgcaacca agcaaagtca    180
ctgtcttcaa atctggatac acactttccc ctctgtagat tcaaaaggtg cttccttccc    240
ggctgtctcc agcttcctta ctctcttttc tggggatttc tttttctctt ctttctgstc    300
ttcctccact gctgaactgc tccctaactg aaacagcccc tgacttagcc caagcatgct    360
tcctttagct gctgtgagaa tttgtcttcc tcaccagcca ggtcctcagg caaagtcctc    420
agccagtgct ttagrgcaac ttcccgcaaa tcagaaactc actgtgattc caaaaatgtt    480
tctgagccct gggacccctg cccccaaaat attttcatct ttcccccaaa cctcctttaa    540
aggaggcatg cataacagtg tgctggaaag gacagttgtt ggntttttgg attttaggca    600
tatttatttt cctgttatgg aaatatgttt tatattaatc tcctatttat tttttatctt    660
atgtttttgt attngtttga taaatccctt ttggtccctc t                        701

<210> 51
<211> 354
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (225)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (235)
<223> n equals a,t,g, or c

<400> 51
ggcagagtcc ggtactcaat caagtgtctt gaatgtaaca agcagatgcg ggnntacatg     60
gtcctggctg cacatttcca gaggacaaca gaggagacag aggggctgac ctgccaggta    120
tgccagatgc tgctgcccaa ccagtgcagt ttctgtgccc accagcggrt ttcatgcaca    180
caagtccccc tactgctgcc cggagtgtgg ggtcctctgc cgctntgcct acttncagac    240
ccatgtaaag gagaattgcc tgcactatgc ccgcaaggtg ggctacaggt gcatccactg    300
tggtgtcgtc cacctgacct tgggcttgct gaaaaggcac atccaggagc gaca          354

<210> 52
<211> 662
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (107)
<223> n equals a,t,g, or c

<400> 52
attacaggcg cctgccacca cgcccagcta atttttgtat ttttagcaga gatggggttt     60
caccgtgttg gccaggctgg tcttgaactc ctgacctcag gtgatnnaac tgcctcggcg    120
tcccaaagtg ctgggattac agctgtgaag ccactgcacc cggccgggaa tttatcaaag    180
gggggactac ttagatttgg ggcttcaaac ctgagtctag cacaatgcag ctggaggcca    240
ggggtactcc tacaaaccca agttctgact ccttccaggg aagtatcagc ttaagaaact    300
tgatcaggaa agtgacamtg gtytttyaaa agagccctct ttaccctccc atccctgccc    360
ttccaacaac tgcaagctgc attccagcca caacgccctt ttctaaatct attttcattc    420
atctcctatt ctggtctgta gccttgattc caaccattga atgcacggag acagcccagt    480
ggcttgtcag attggtaaat aatgacacct ggtggataaa tgttacattc tagaagacta    540
ttctggtcag cctaggtctg aaacactaag gagacttggc ctgagatagg gccatccact    600
tcctacaggc actctgcttt tattattaaa aatagtcact ttgttactat aataaaattt    660
aa                                                                   662

<210> 53
<211> 640
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (157)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (638)
<223> n equals a,t,g, or c

<400> 53
ggcagagttt cccccagtgt attccttgca taggcaacct ctgctgctta aatgttttgg     60
agactttggg atgtctgatt tcaactgtac cgtgaacagg tagtggcttg acttagtaag    120
catctgaagg actgttttgt tctactcttg cagagtngag tagttttcaa aaggaaagga    180
aaggaattgt tgagtgggac ctatgamgta tagcaggatg gatagaatat gaggcagatg    240
ggtcctagtt tgctaaagag cttgggccgt ctgataagtt gtctttcttg ccaaacaagg    300
gagtcacgtg gggtatacac attgtataag cttttcagtc accgaggttg cctgtccttc    360
ctgcctccct gtttcgttgc ctccttgcct cccttcctca cttcccttcc tttcccacct    420
ccctgtccac accccttcct tcccctgcct ctcttcgttt ccctttcctt cattctttcc    480
tgccctcctg cctacttccc tgcctccttt cctttacctc ttgtcttagg tctattttct    540
gttgctgtaa ccacagattg ggataatggg ataaatttta aagaaaagag gatttatcgc    600
tgggggtggg tgggcttaat ggtttcaaaa tcccaggnat                          640

<210> 54
<211> 553
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (508)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (546)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (548)
<223> n equals a,t,g, or c

<400> 54
cccagatgcc tgccagagtc tcccgaccac aaacccagca cgttgatagt tgtgtccttg     60
ccatatacac agtggaatct tttgcctttt ctttcctttt gtgcctttaa cattttcccc    120
tttgtatctc ctaaatttgc atactttgta gcaattcttc aaaacgatat taatatgccc    180
attttataga tgagggatct gaggctcaga aagtttcagt gtcttgttta tgctgcctgg    240
catcagtctg aatgctccga gccttaagcc caagcctctt ttcaacagtg ctgcagccct    300
gtcaaagatg tacttgtgaa ttcaaaacag cactcaggca tataggttac attggcacca    360
ggaaacctaa gcagtatttc catgaccaaa ttctaagtga attcaacacc aaaggtggaa    420
aaggaaatgt tctttgctct ctgtatagat tcctcttctg cttgcttggg ttttacaaag    480
ttcttctaat ttttatgtgc gattgggnca atgcagtttt ggtaaagttg cttaaaaccc    540
taactngntt act                                                       553

<210> 55
<211> 488
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (395)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (471)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (478)
<223> n equals a,t,g, or c

<400> 55
tcgacccacg cgtccggttt tccgtctcca gcgcatctgg agaggcacct gtcccagcac     60
catagtgact ggatgtgtgt gcggaagaag gaaygcggtg ccctctactc caagggcaag    120
agctactgga gtctttttga aaataaaagt gttgttacat gtgtgatatg taagtggcat    180
gtgctaatac acattttctt tcttattaac agtggttcag cactgagtca tgcttgcttc    240
tgctacgcac tgatttgttc tattccagtt tycacgtaca tcgttttggt gacatctctg    300
cgttatcatt tatttatatg gagtgtattt tctccaaaac ttctctacga gggaatgcac    360
ctgctcatta cagctgctgt ctgtgtattc ttcanggcaa tgggtcaaac cagactcaca    420
cagtcttagg ctaagstgga mcactgggaa aaaatataca tggcttaaag nctgctgnta    480
ttctaaat                                                             488

<210> 56
<211> 599
<212> DNA
<213> Homo sapiens

<400> 56
caataaccct cactaaaggc acaaaagctg ggtacgggac cccccctcgg taccctcatc     60
tggttaggcg tccatatcag ttggacggca gctctcatta ttctgccctt cgtggcgctt    120
gccggctatg ttgtgccctt tgctttctcg ggccctacac accgggcagc ccgccacatg    180
ctgcgcgtcc gcggtgacct cacccagcat ctcaccgaca ctacacaggg catgcgggaa    240
gtcctcggat tcggctatgg ggatcgtcgc ctcgccgaaa ctgaccgtat ttccgaagag    300
gttggcaatg ctgctttcgc gaaccgcctc acctccggta tccgtcgcag tctctgtgag    360
ggcctccgcc ttttcgcagt tgtgaccact gtacttgttg gtgctgacgc tgttcgccgc    420
ggcgacctca gcattcccca cctggctatc tgcgcaacag tggcattggg agttttcacc    480
ccggcccgcg gtacagaaga tttcgccgac gatttggaac gctcctttgc cgccgccgaa    540
cgcatgagcg ttatyaaata ccgtgaaccg cctgmagccc gggggatcca ctagttcta     599

<210> 57
<211> 429
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (382)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (415)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (429)
<223> n equals a,t,g, or c

<400> 57
tcttgagtga agatgaaaat gacaagaagc aaaatgccca gtcttcggac gagtcctttg     60
agccttaccc agaaaggaaa gtctctggta agaagagtga aagcaaagaa gccaagaagt    120
ctgaagaacc aagaattcgg aagaagccgg gacccaagcc cggatggaag aagaagcttc    180
gttgtgagag gtgatgcctg caacgcgagg ctcgccctgc ctgtcggggc cggggctcca    240
tgcatgctct tcattgcagg gaggagcttc ccaccatcta caagtgtcct taccagggct    300
gcacggccgt gtaccgaggc gctgacggca tgaaggtgag cactggctgt gctgacccag    360
gcccggcagc tgtcatgttg anctgggggg agtagcagtg tttcttgcag ctaanttcag    420
acttggtgn                                                            429

<210> 58
<211> 917
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (833)
<223> n equals a,t,g, or c

<400> 58
tcgagttttt tttttttttt tttttttttt tttttttttt tttttttaat aaagttgttg     60
tttatttcca cctgccagct ccttcatggg gcgaggggtc ggaggctgga racccgggag    120
gaaagcaagt caagacaaat gcttgaccca cggggactcc aggcctggcc tgcagccact    180
ctggtggact tggctttggg tctggggtct tagtgtctta ggcttgaggg agaggggcag    240
tgaagaggtg ccctcagcct ccccattacc ccgcctctcc tccacagaac ccacatccta    300
ggctggccta gccacaagca agggggctca ggaggggccc acgcggatgt gagggttcat    360
gagtgggtcc aggttgggat cgctgtcagc tgcggcccgg cctaggcgag acatgagggc    420
aaggagggcc aggaagccca gcagtcccaa gagtagcagc agccccgccc gctggagcag    480
ggtcagcggy cgcttccgag acccagcccg gctccttagc agccgggcca gccaacccaa    540
ggccggccga cgtcggtact tgtcatcgtc acagtctcca tggaggcctg gtgtccggtc    600
atcatcccgc gtatcataca ccttcctagg ggcgtgagtc aagggctcag gattgcccat    660
gtggatcact gtgtgctgct cgggccggcc tggggaagct gggggccggg gggctcggct    720
gtagaaggct ggggcagcag aggcgctgtc tacctcctct ggtccagggg tactgctggc    780
attaaaacta gaccagtcag agaagtcaga cgtgttgagg ggctcgggct ctngggctca    840
ccacctcatc gatcagaggg aggcccagtc ctgcccgggc ccagttgact gtggccaact    900
ttctctctca gtgcgga                                                   917

<210> 59
<211> 703
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (594)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (597)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (691)
<223> n equals a,t,g, or c

<400> 59
tctttctctg tctagtttcc tctgttctca gtttatattc tatgttatca gtctctcttt     60
ccacagtaca aacatccatc ctttctcctg tgcaattctg tctctccctc ttattatctt    120
tatttgtact ttttccttcc tccctgtcta ggcattgggc atgtgcctct tcttagcctg    180
tgattttgcc ttgggactga tgataaatta tttccagatt caatcagccc tggtcctacc    240
ccagtccaat cagaagtatg ttggtgggaa tcaacctgat cctggccctt tcttcttctc    300
cattttcatt cgtaatcccc ctcagcagat ctttacaagc agtttcctta tagctcatgt    360
atctttaggt ctttgccttc caagcactgt acagaatact ttgtggttcc tttttagtct    420
gacattttgt ggagcagtga agcgtgctca gagacataat cagctgaaga gaaaaaatcc    480
acccatggat ttatatcagc taaatactaa taattgattt tgtttgatgt gcccataatt    540
tttaaagctg caatataata taatgrggga ccacaggwaa tttcyccctg tcanttngtt    600
ttggctggat gggggtgggg gagtaattgc ytaaagttta ccmtacacat taaatctcta    660
aataatcctg gttgggctgn caacggtgag nggtttaaca aaa                      703

<210> 60
<211> 508
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (252)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (472)
<223> n equals a,t,g, or c

<400> 60
gccggaccca gcaggacggg atatctccat ccgccctctc ctggagcact gtgagaacac     60
ccatatgacc atctggcttg gcatcgtcta tgcctacaag ggacttctca tgttgttcgg    120
ttgtttctta gcttgggaga cccgcaacgt cagcatcccc gcactcaacg acagcaagta    180
catcgggatg agtgtctaca acgtggggat catstgcatc atcggggccg ctgtctcctt    240
cctgacccgg gnaccagccc aatgtgcagt tctgcatcgt ggctctggtc atcatcttct    300
gcagcaccat caccctctgc ctggtattcg tgccgaagct catcaccctg aggaacaaac    360
ccagatgcag caacgcagka acaggcgatt ccagtttcac ttcaggattc agaaggaaag    420
aagrttytta aaacgtccac cttcgggttc accatgtgaa acccaagcca gnacatcccg    480
cctgggaggg ccttacattc agaaaacc                                       508

<210> 61
<211> 499
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (63)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (305)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (356)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (371)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (447)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (497)
<223> n equals a,t,g, or c

<400> 61
cgaccgatca cagaanggcg cagtgtgtga attcggcttg ycaccaacgw gttcatcctg     60
wgnctggcca tcgccgacga gctcttcacg ctggtgctgc ccatcaacat cgccgacttc    120
ctgctgcggc agtggccctt cggggagctc atgtgcaagc tcatcgtggc tatcgaccag    180
tacaacacct tctccagcct ctacttcctc accgtcatga gcgccgaccg ctacctggtg    240
gtgttggcca ctgcggagtc gcgccgggtg gccggccgca cctacagcgc cgcgcgcgcg    300
gttgnagcct gggccgtgtg ggggatcgtc acactcgtcg tgctgccctt tcgcantctt    360
tcgcccggct nagacgaaga gcaaggccgg cgccaatgcg tgctaatttt ttccggcaac    420
ccgaaggctt tctggttggc gcgcgancgc ttcttaaaag gttctgctgg ggtttgcaat    480
ccccgttgtt ccaacantt                                                 499

<210> 62
<211> 926
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (853)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (864)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (876)
<223> n equals a,t,g, or c

<400> 62
tgatcgccag gctggcagcc ccaagtggag tgaccgggcc cctaaatgtc tcctggaaca     60
gctcaagcca tgccatggtc tcagtgcccc tgagaatggt gcccgaagtc ctgagaagca    120
gctacaccca gcagggccac catccacttc tcgtgtgccc ctggctatgt gctgaagggc    180
caggscagca tcaagtgtgt gcctgggcac cctcgcattg gagtgacccc ccacccatct    240
gtagggctgc ctctctggat gggttctaca acagtcgcag cctggatgtt gccaaggcac    300
ctgctgcctc cagcaccctg gatgctgccc acattgcagc tgccatcttc ttgccactgg    360
tggcgatggt gttgttggta ggaggtgtat acttctactt ctccaggctc cagggaaaaa    420
gctccctgca gctgccccgc ccccgccccc gcccctacaa ccgcattacc atagagtcag    480
cgtttgacaa tccaacttac gagactggat ctctttcctt tgcaggagac gagagaatat    540
gaagtctcca tctaggtggg ggcagtctag ggaagtcaac tcagacttgc accacagtcc    600
agcagcaagg ctccttgctt cctgctgtcc ctccacctcc tgtatatacc acctaggagg    660
agatgccacc aagccctcaa gaagttgtgc ccttccccgc ctgcgatgcc accatggcct    720
attttcttgg tgtcattgcc cacttggggc ccttcattgg gccatgtcag ggggcatctt    780
acctgtgggg aagaacatag ctgggagcac aagcattcaa cagccagcat tccttgagcc    840
tccttcattg ccnggggacc agcntgggga acacanttag gcaggagcag ggagttacct    900
tttctttcca catggaccac cattcc                                         926

<210> 63
<211> 556
<212> DNA
<213> Homo sapiens

<400> 63
ggcagagctg ctctgccatg atgacactgg sttctacagc tctcattccg ggcctgactc     60
atggggcagg cagatgggtg atggagcagg gaccctccca gcccagtcac ctgctgggga    120
attccaggct caccatgcag cgtgtgcatg cttgtgattt ttgtttcctt gtttggaaca    180
gaacaaagga acatgaggac atttggatct ttttcctgcc tcttctccat gtgtatattg    240
gagtttgccc taaatctctt ctgctacaag atggggtaga aataaataca catgcagagt    300
tgtgtcccct gcagccacac tcaacttgtg cttcctcttg tgtcctgaca ggggaatgta    360
ggtgacattt ctccccattc ctcttggctc tgtttgccct ggggaatcaa ggttagagga    420
cagtcggggg ratgggataa atgccagtcc tggaggtccc actggaagca gcgaggggaa    480
attcctgagg aaatactatt tgagatccta acagtactct tacgtgctta gcagtttatg    540
gtttacaaag tccttt                                                    556

<210> 64
<211> 473
<212> DNA
<213> Homo sapiens

<400> 64
acccagggta cgacgaagca gtcggcggga gcccacggtc gctgggcggt gtctttaagg     60
gagggggcgg agccacgtct ctggacatcc tgagcccaag tcccccacac tcagtgcagt    120
gatgagtgcg gaagtgaagg tgacagggca gaaccaggag caatttctgc tcctagccaa    180
gtcggccaag ggggcagcgc tggccacact catccatcag gtgctggagg cccctggtgt    240
ctacgtgttt ggagaactgc tggacatgcc caatgttaga gagctggctg agagtgactt    300
tgcctctacc ttccggctgc tcacagtgtt tgcttatggg acatacgctg actacttagc    360
tgaagcccgg aatcttcctc cactaacaga ggctcagaag aataagcttc gacacctctc    420
agttgtcacc ctggctgcta aagtaaagtg tatcccatat gcagtgttgc tgg           473

<210> 65
<211> 1204
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (981)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1070)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1105)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1159)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1201)
<223> n equals a,t,g, or c

<400> 65
ctatgcgaca atcctaggaa caccagctga caatggactg ccactgacgg attcctgtgg     60
atatggggaa cccagagctt actcacagct accttatcac tggcaaggta cttgcttcct    120
aggcacaatt caacctggat tctttttact tccgaagcag gcgggcaaca ccctcagagt    180
ccctgtgtat gatmaccaga gaaaaatgat ccttggaggt aggagggagc caaagattgt    240
gagaggacga gtggcctcyg caacggatca ttgaatacta tggtcctgcc acttgggcag    300
aggatggttc atggggttat cgcactccca tatatatgcc aaatagagcg attagactac    360
aagctgttct agagataatc actaaccaaa ctgcctcagc cctagaaatg ctcgcgcaac    420
aacaaaacca aatgcgcgcg gcaatttatc aaaacaggct ggccctagac tacttattag    480
cagaagaggg tgcgggctgt ggtaagttta acatctccaa ttgctgtctt aacataggca    540
ataatggaga agaggttctg gaaatcgctt caaacatcag aaaagtagcc cgtgtaccag    600
tccaaacctg ggagggatgg gacccagcaa accttctagg agggtggttc tctaatttag    660
gaggatttaa aatgctggtg gggacagtca ttttcatcac tggggtcctc ctgtttctcc    720
cctgtggtat cccattaaaa ctcttgttga aactacagtt aacctcctga caatccagat    780
gatgctcctg ctacagcggc acgatggata ccaacccgtc tctcaagaat accccaaaaa    840
ttaagttttt ctttttccaa ggtgcccacg ccacccctat gtcacgcctg aagtagttat    900
tgagaaagtc gtccctttcc ccttttctat aaccaaatag acaggaatgg aagattctcc    960
tcggggcctg aaagcttgcg ngatgaataa ctcctcctcc tcaggcccag tcccaaggta   1020
caaacttgca ccagcaggca agataggcag aggcaggaag agagctgggn tgggaaggac   1080
acgttacccc ctggaaggtt caagnrgggg aggtcgcctg ggtactacat aggcagttca   1140
cgtttaggct tggggacant tcctgttttt acagagggat tttttaaaac ccctggcccc   1200
ntcc                                                                1204

<210> 66
<211> 480
<212> DNA
<213> Homo sapiens

<400> 66
caagatgcaa gcaccagcct tcagggacaa gaaacagggg gtctcagcca agaatcaagg     60
tgcccatgac ccagactatg agaatatcac cttggccttc aaaaatcagg accatgcaaa    120
gggtggtcat tcacgaccca cgagccaagt cccagcccag tgcaggccgc cctcagactc    180
cacccaggtc ccctgctggt tgtacagagc catcctgagc ctgtacatcc tcctggccct    240
ggcctttgtc ctctgcatca tcctgtcagc cttcatcatg gtgaagaatg ctgagatgtc    300
caaggagctg ctgggcttta aaagggagct ttggaatgtc tcaaactccg tacaagcatg    360
cgaagagaga cagaagagag gctgggawtc cgttcagcag agcatcacca tggtcaggag    420
caagattgat agattagaga cgacattagc aggcataaaa aacattgaca caaaggtaca    480

<210> 67
<211> 525
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (498)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (506)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (509)
<223> n equals a,t,g, or c

<400> 67
cccacgcgtc cggccatccc actgctcgtc tccgtagccc ctggagctgc ccgtggtatc     60
ggataccggc gcgtgcggtc cccgagtcct ggctgccctc gcccggctgc cagccttctc    120
agccagtcat gttggagcat ctgagctcgc tgcccacaca aatggattac aagggccaga    180
agctagccga acagatgttt cagggaatta ttattttttc tgcaatagtt ggatttatct    240
acgggtacgt ggctgaacag ttcgggtgga ctgtctatat agttatggcc ggatttgctt    300
tttcgtgttt gttgacactt cctccatggc ccatttaccg ccggcacccc ctcaagtggt    360
tacctgttca agactcaggc tcagaagaca agaaaccagg ggaaaggaaa attaagaggc    420
atgctaaaaa taactaaatt aggtttttca tgatttagct ttactcttgc acctgntttc    480
cttttgcttg agaagaantc agtttncana ctccaaaaca tgggc                    525

<210> 68
<211> 1113
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (726)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1057)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1073)
<223> n equals a,t,g, or c

<400> 68
ctctagtgcc tgggcatggg cccacccaga gcacctgtct ggaggatgcc gagagggact     60
ctcgtctgtg ggacgggatc caagagtttg gggattaggg gtattagggc ttttcagctc    120
cagcttcctg atgaaagggc tgtctttaca ngcccaaccc tcagaccctc gccttccaag    180
gcaggcccct cagcctggcc tgctctcacc acctcctcca aagcactgag gtcctggcag    240
ggctcctctg aggccttgga cgaggacgtg gagtcatcag tgttgccctt gcccctaacc    300
tcagcccgag ggtctccagg atgttgcctg gcccaggact tgggacagtg gccttgtctt    360
tgtcctcccc accccccagc cctagggaca csccaggcag tcctgggtgt ggacacgatg    420
aagcaccggc tccataagac accttttggg gaagtggttg tgcatatttt atttttcttt    480
gacttgtgtg agttcaaagt aaacacyacc accgtggaca actcttgaat taaatcccac    540
tagagcgagc tttaaaacta atctgagcat aacccccaac gtggctctat gcttgtgtac    600
ctttgcacat attttgttta gtacagtttc atatttgagt ttgcagaatt atcctaatag    660
tctttttttg gctaatattt ttataacgtg gttcttattt aactgtctag ttttgataga    720
atttanccag gtctggctga atgaagatgt tggcacgtgt cattttagtg gtttaaatcc    780
tcttatttat ggttttaact ctaagaaaat tttaaaagga agagatgttt ggatgacaaa    840
aaaatgcctt attgaaaaac taaagcaaat tctttatagg aagaaaatat gggaatttga    900
ttacacatag atgatgatgt ttatttaaaa aaaaaacaac agcaacaaaa aatcctagcc    960
tccagttgcc ttttcctttc tttagctcct gtttttggtg aattactaaa ctgattgact   1020
ttcagccttt ttggctagat cctgagaggc tattttnctt acgaatatac cancatcctg   1080
aaagttaaag aaaaaatcta atgtatgatg tga                                1113

<210> 69
<211> 627
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (566)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (589)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (602)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (624)
<223> n equals a,t,g, or c

<400> 69
acccacgcgt ccgtgataaa ccagtggaat gtggatacca tgtcaagact gaagatccag     60
acttgaggac ttcctcctgg attaaacagt ttgatacttc cagatttcat cctcaggatc    120
taagtagaag ccagaaatgc atcagaaagg aaggttcatc agaaattagt cagagggtac    180
aaagtaggaa ttatgtggac agcagcggct caagccttca gaatggaaag tatatgcaga    240
attcaaacct gacttcgggg gcgtgccaga taagtaatgg cagtctaagc ccagaaaggc    300
cagttggtga aacttccttc tcggtgcccc ttcaccccac caagagaccg gcatcaaatc    360
caccacctat cagcaaccag gcaacaaaag gtaaacgtcc aaaaaaagga atggcaacag    420
ccaaacaacg tcttgggaag atccttaagt tgaacagaaa tggccatgca cgtttctttg    480
tgttgacaga gcttgctgtt gcagccattc ttccctttgg agaccagtct aggggtgcag    540
gagcctggga gcttccgctg tccccntgcc tggagcagtt tgtgtgtant agttaagaac    600
antgcccgaa gaacagattg aacntga                                        627

<210> 70
<211> 380
<212> DNA
<213> Homo sapiens

<400> 70
ggagaagcgg agaatctctt catgtctagg gaggggtaaa gagaatatga ttcccctctg     60
ttgggtgttg ggagacggag gcatggactg catgacctct caaaagtcct tggggactag    120
aacgccttca ctctcctgtg gattacccca cccctccctg agccatggat ctggccgggg    180
tattagtaag gtactctgct ccctaggaac agtctccaga attttactgt gttcccctca    240
rccctctgct ggaattgtga gaaktggggg taagagaagr aggagacagg attggaagag    300
acctgggggc aaagagctct ctgtgcatcc ttccctgctg ctcttcctcc tagccatgtg    360
gcccagcttc atccttcccc                                                380

<210> 71
<211> 754
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (208)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (731)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (740)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (743)
<223> n equals a,t,g, or c

<400> 71
cagacttcaa acctcagaat cataatgaag tccagtctac cacaccaccc ttcactactg     60
ttgattcaca gaaagactgt agaaaatttc cagttccaca gaaggatggt agtgctttgg    120
aggattctag cacttcaggg gcatcctgtt ccaagtcaag accacattta gctgggacac    180
atacttctct tagacttccg cagaaggnaa aaggaacctg tattcttgta ggtggtcatg    240
aaatcacttc tggattagaa gtaatttctt ccctaagagc aattcatggg ttgcaagtag    300
aagtttgtcc tcttaatggc tgtgattaca tcgtgagtaa tcgcatggtg gtggaaagga    360
ggtctcaatc tgagatgtta aatagtgtca ataagracaa gttcmttgag cagatccagc    420
acctgcagag tatgtttgaa agaatatgtg tgattgtgga aaaggacaga gaaaaaacag    480
gagacacatc aaggatgttt aggagaacaa agasctatga cagcctgctg actaccttaa    540
ttggcgctgg aatccgaatt cttttcagkt cctgccaaga agaaaccgca gatttgctaa    600
aggaacygtc tttagtggaa caaagaaaga atctcacttc aagaaatctc catgtatgca    660
caagtaactc atcagaaggc tgaggagatc tatagatata ttcactatgt gatttggaca    720
tacaaatgtt naccaaatgn tcnttaacca agat                                754

<210> 72
<211> 749
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (718)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (725)
<223> n equals a,t,g, or c

<400> 72
gtgggaagaa ggtggtgtct tcgcctgggt atcaaatact ctggggccga gatggggatt     60
tgcagcgatc tcatttggct atctgcaaat cgccattggt tttattccga tgctctattt    120
cgtgttaggg gcactctcct acatcctgaa atggccagcg ctgaatgaag accccattac    180
caaaactatt gcagcactca tcattctttg ggcgctggca ttaacgcagt ttggtggcac    240
gaaatacacg gcgcgaattg ctaaagttgg cttcttcgcc ggtatcctgt tacctgcatt    300
tattttgatc gcattagcgg ctatttatct gcactccggt gcccccgttg ctatcgaaat    360
ggattcgaag accttcttcc ctgacttctc taaagtgggc accctggtag tatttgttgc    420
cttcattttg agttatatgg gcgtagaagc atccgcaacc cacgtcaatg aaatgagcaa    480
cccagggcgc gactatccgt tggctatgtt actgctgatg gtggcggcaa tctgcttaag    540
ctctgttggt ggtttgtcta ttgcgatggt cattccgggt aatgaaatca acctctccgc    600
aggggtaatg caaaccttta ccgttctgat gtcccatgtg gcaccagaaa ttgagtggac    660
ggttcgcgtg atctccgcac tgctgttgmg ggtkgtctkg cggaaaatcc cctcctgnat    720
tgttngggtc cctcctcccc gggaatgtt                                      749

<210> 73
<211> 1067
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (368)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (383)
<223> n equals a,t,g, or c

<400> 73
tcccactcat ttttgaagta actctggaac atcaggagag cattctgggt aataccatgc     60
aaagtgtgat tgcattactc agcaatctag ttgcctgcaa agattcgaat atggaactac    120
tttatgaaca aggacttgtc agtcacatct gtaacctgct cactgaaact gccacactgt    180
gcttggatgt ggacaataaa aacaacaatg agatggcagc tccactgctc ttttccctgc    240
ttgatatttt gcacagcatg ctgacctata cctccggtat tgtacggctg gctttgcagg    300
cccagaagtc tggctcagga gaggaccctc aggctgcaga agacctgctg ctgctcaaca    360
gacctctnga cagacctgat tangcctgct catttccact gctttcctaa tgaagatcct    420
gagattttga tgtttcatcc aagtgcctgt cyatactggt tcagctgtat ggagggaaaa    480
cccggacagc ctctctcctg aaaatgtgga aatttttgct catttactga catccaagga    540
ggacccaaag gagcagaagc ttctgttaag gattctcaga agaatgatca cctccaatga    600
gaagcacttg gagagcctca agaatgcagg cagcctcctg cgggctctgg agcggctggc    660
ccctgggagt ggttcatttg ccgacagtgc ggtggctccc ttggccctgg aaatcctcca    720
agccgttggg cactaggcaa gaaggtgctt agcacaagcc cgccctgtgc cccagccctc    780
ggatgcataa gcaaggtcag ctcccagaca cctttgccac atcccctcac agctgtcttt    840
ggacctaata aagtcagctt aacccagaac ctggtggccc aagtgctcac taaccccagg    900
gcctagaaaa ctgactcaga atggacttcc ttggttcctg tggaatgcat ctgggaagcc    960
caggtttgtt agctgttctc agaaatgttc tttccctctc tgtgtgggcc aggtgggcta   1020
aggttagcac tgcctgtggt aataaagcag tggatcaaag cacaaaa                 1067

<210> 74
<211> 520
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (474)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (503)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<400> 74
atggtccact gtcctcacga gttgctacag atgcctcttt cactgttcag tcagcgttcc     60
tgggtaactc agtgcttgga cacttggaaa acatgcaccc tgataactca aaggcacctg    120
gcttcagacc accttcccag cgagtttcta ctagtccagt tggtgactct cctattccat    180
ctgtttcttc gggatcatct tcacctcttt cagccacttc tgccccacca acgttgggcc    240
aaccaaaagg agtcagtgcc agtcaagatc gaaagatacc tcccccaatt ggaacagaga    300
gactggcccg aattcggcaa ggagggtctg ttgcacaagc cccggcgggg aaccagtttt    360
gtcgstcccg ttggacacak tggratctgg ttcatttggt gtcaatgctg tgtcagaagg    420
cttatcaggt tggtcgcaat ctgtgatggg gaacatccaa tgcatcaaca ttancggacc    480
cagcaaattc tcccaaatca gcnatggaga aagatgatcn                          520

<210> 75
<211> 671
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (574)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (608)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (622)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (627)
<223> n equals a,t,g, or c

<400> 75
ttgtgaacct agaaaaggca ccactgaaag tacttgaaaa ctggtggtca gtacttgaac     60
ctccactatt cctcaagata gtagaacttt ttaaggaagt tgtggtacat cttttgaaac    120
tctacaagat cggtattccc ccttctgaaa raagattttc aacagttttc ttcatactgc    180
attaaaggtt ttagaaatac tacatagggt aaatgagaaa atgggacaga ttatacagta    240
tgataaattt tatatacatg aagtacaaga attgatagac atargaaatg attatatcaa    300
ctgggtccaa cagcaggcct atggaatgtt ggcagatatc cctgttacaa tctgtacata    360
tccatttgta tttgatgccc aagcaaaaac tactctgtta cagaccgatg cagtcttaca    420
gatgcagatg gctattgatc aggcccacag gcagaatgyc tccyctcttt ttctcccagt    480
gattgaatct gtgaatccct gcttaattct agtggtgcgt agagaaaata ttgtaggaga    540
tgcaatggaa gtccttagga aacaaagaca tagnttacaa gaagccactc aaggttatat    600
ttttttgnga ggtgctttgg tncaggnggg tgcgcaagaa ttttcttgct catcatgggg    660
gattattggt c                                                         671

<210> 76
<211> 866
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (690)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (839)
<223> n equals a,t,g, or c

<400> 76
gtcagccctg aagctaacaa agagatgcca gggctggacc ctaatttgag aagtgcagtt     60
tccatagcaa ggcgtgtaca agatccatta gctgagctag tgaaaattga gccaaagcac    120
attggagttg gaatgtatca gcatgacgta tcccagactt tactcaaggc aacactggac    180
agtgttgtag aagaatgtgt cagctttgtg ggagtggata ttaacatctg ttcagaagtt    240
ttgttaaggc atattgcagg actcaatgcc aacagggcca aaaatattat tgaatggcga    300
gagaaaaatg gaccctttat caaccgagaa cagctgaaga aagtgaaagg gctgggccma    360
aaatccttcc aacagtgtgc tggcttcatc agaatcaacc aggrttatat ccgaacgttt    420
tgcagtyagc aaactgaaac ttcaggccaa attcaaggag ttgctgtgac atcttcagca    480
gacgttgagg tcacaaatga gaagcagggc aaaaagaaga gcaaaactgc agtgaatgtt    540
ttactgaagc caaatccttt ggaccaaact tgtattcatc cagaatcata tgacatagca    600
akgaggtttt tgtcmtccat tggagggaca ctgtatgagg ttggaaagcc tgaaatgcaa    660
caaaaaataa attcattcct tgaaaaggan ggaatggaga aaattgcaga aagattgcaa    720
acaacagtac acaccttaca ggttcatcat agatgggtct tcagccagcc tgaaggcttt    780
gactttcgaa cagatttttg ataaacctgg attttcaagg aggaaggcat agtatgccng    840
gggagtttct gccaggtttg gggaca                                         866

<210> 77
<211> 573
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (506)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (548)
<223> n equals a,t,g, or c

<400> 77
gagcgcctnc gctgcgtccg cccgttccat agtgccgcgg atcagggcgg acgtgaagcc     60
tttagcgtgg tcctcagacc tcgctgtgcc cggggtgggg cgtgtcggct gctaccgaga    120
acctgctcgg gggacgcgty cgtcaaccgg aatccagggg acagaagctt ccgacgcgcg    180
aggcctcggg aggagcgtca acttggtaac tctcctccgg tcgcaagacc tggaagtggc    240
ctcagggggt cgcccttcct gtccgtcgtg gatgaagggg accacttggc ttcagaaatc    300
cccgctggcc tccgcctccc ctggggtttc cctttcggcg caggcggggc agcggcgtca    360
tcacaaccat cgccacccca gtaatcacag cgagcggccc tttgcgcacg cgtggagcct    420
tctmaggcct cagtacttct macttcgccc ggcaaggctg gccaggaggg gtgcattctc    480
cctttccgcg tatttcaaga ccactncctt ctgcatgctc ggtgtcccag tctgtctcct    540
cgctgccncc cgaggcctgg aaatgaagca aag                                 573

<210> 78
<211> 445
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (337)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (397)
<223> n equals a,t,g, or c

<400> 78
ggcacgaggt ttcactgaag aatgatctgg ctggactgct tatttggggt agccctgaag     60
ccagaatctt cagatctttt cttttgtgtc agttatgttc ctcagaaatg gtttttcatt    120
ctcctgcctg gcagcgctgt tcataagatg attgtggaca ggcagtatat gggcgtgtct    180
aagcggaagt gcatcgtgtg gggtgtcgcc ttcttgtccg atggcactat cataagtgtg    240
gactctgctg ggaaggtgca gttctgggac tcagccactg ggacgcttgt gaagagccat    300
ctcatcgcta atgctgacgt gcagtccatt gctgtanctg accaagaaga cagtttcgtg    360
gtgggcacag ccgaaggaac cagtcttcca ttttcanctg gtccctgtga catctaaaca    420
gcagtgagaa gcagtgggtg cggac                                          445

<210> 79
<211> 518
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (354)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (414)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (457)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (506)
<223> n equals a,t,g, or c

<400> 79
agggccagtg gatgtgggag tgctggggaa gccccacgga gagtgacccc accccccttg     60
aggacaggtg gctgcattca cagagacggt gatggtgggg atgcgtcctg ccttcgctct    120
agcccagccc aggctccagc cccatcaccc tcattccagg gagagggtga aagctgcgcc    180
cagggacaga gccaagacgc aggcccagac agctcactct tcccctcagc ccctctgccc    240
acttgtgcac actgtcttca ttctctttcc tttagctggg cccctccact gggaaaagat    300
gaaacgtctt ctcagatcca gttcaaaaga ctcccaagga aagtcctgct tggnccacac    360
tgggtcatgc gttaaaacct gggaccaatt aagctgctgt ttgggccaaa aagntggctg    420
tgattggcaa gttccaacgg gagcctccgt gggtttnggg ggctggcccc ggccccaaga    480
aaggcaaact ggccttggaa ggggcncaag gaaccctt                            518

<210> 80
<211> 492
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (284)
<223> n equals a,t,g, or c

<400> 80
tttaagtttg ctgtttctcc tctctctctc tgcaggggtg ctgatggtct gtatagtgat     60
tggtgctcga aagctcgggg tcaacccaga caacattgcc acgcccattg cagccagcct    120
gggagacctc atcacactgt ccattctggc tttggttagc agcttcttct acagacacaa    180
agatagtcgg tatctgacgc cgctggtctg cctcagcttt gcggctctga ccccagtgtg    240
ggtcctcatt gccaagcaga gcccacccat cgtgaagatc ctgnaagttt ggctggttcc    300
caatcatcct ggccatggtc atcagcagtt tcggaggact catcttgagc aaaaccgttt    360
ytaaacagca gtacaaaggc atggcgatat ttacccccgt gcatatgtgg tgttggtggc    420
aatctggtgg ccattcagac cagccgaatc tcaacctacc tgcacatgtg gagtgcacct    480
ggcgtcctgc cc                                                        492

<210> 81
<211> 1186
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<400> 81
ggcacgagcc ggcaagccga gctagggtga aaactggggg cgcaccagga tgtnngacag     60
aaaagcagaa gatgagactc tgttcattca cttttcctag gcccatcctg tggtcatctt    120
tccccctccc atcatacctc ctccttcctg gagcctctgc cggcttggct gtaatggtgg    180
cacttacctg gatatttcag tgggaggatg aaaggcgaga ctcaccctac gcggtgggac    240
agatggggag aggaaaaagg cagagatggc caggagaggg gtgcaggaca aaccagagag    300
gttgggtcag gggaaaaggg tggggagaaa gaggggtgca ggccctgcag gccggttagc    360
cagcagctgc ggcctccccg ggcccttggc atccaacttc gcagacaggg taccagcctc    420
ctggtgtgta tcataggatt tgttcacata gtgttatgca tgatcttcgt aaggttaaga    480
agccgtggtg gtgcaccatg acatccaacc cgtatatata aagataaata tatatatata    540
tgtatgtaaa ttatggcacg agaaattata gcactgaggg ccctgctgcc ctgctggacc    600
aagcaaaact aagccttttg gtttgggtat tatgtttcgt tttgttattt gtttgttttt    660
gtggcttgtc ttatgtcgtg atagcacaag tgccagtcgg attgctctgt attacagaat    720
agtgttttta attcatcaat gttctagtta atgtctacct cagcacctcc tcttagccta    780
attttaggag gttgcccaat tttgtttctt caattttact ggttactttt ttgtacaaat    840
caatctcttt ctctctttct ctcctcccca cctctcaccc ttgccctctc catctccctc    900
tcccgccctc ccctcctccc tctggctccc cgtctcattt ctgtccactc cattctctct    960
ccctctctcc tgcctcctgc tgccccctcc ccagcccact tccccgagtt gtgcttgccg   1020
ctccttatct gttctagttc cgaagcagtt tcactcgaag ttgtgcagtc ctggttgcag   1080
ctttccgcat ctgccttcgt ttcgtgtaga ttgacgcgtt tctttgtaat ttcagtgttt   1140
ctgacaagat ttaaaaaaaa aaaaaggaaa aaaaaaaaaa aaaaaa                  1186

<210> 82
<211> 2031
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (41)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1855)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2016)
<223> n equals a,t,g, or c

<400> 82
caattaaccc gtttgaggcc taggttgttt ggcaagcccc nggcctaaag ttttaattcg     60
gcagagccaa gggcctgaaa ggaagggaaa ggggagggta gcgggagggt agcaggtgag    120
ttcctagggc tggaaggttt agcagcagcc tggtgcagtg ccctgtcatc aagacaaacc    180
cacggtcctc ctgggtgcct accaagcttg gtttgtacaa aagcaaggtg ggagtctatt    240
tttgtacatg agatacatca cacttacctg tgggccagta ttgtgaagtg agtctgagtt    300
gtttacactg atgccttccc tgcccaccac aaattgtgta catagtcttc agaatgatac    360
cacccctttc cccagctccc aaccaagagc tggttctagg cctgtgttat atgtcatatt    420
tagcgttttt atatatgacc tttgatttct gttgtttgta ttttagcaca gtgtatgcac    480
cttcatttaa atacatctgt gtgcatacag atacgcatat atgtgtgtgc gtatgcatat    540
atctctcatc tgtagtttcc aagagttcag ctgaagcaga tggagtcctg cagcccagga    600
gacaccctgc atccctgcta atagtgtttg ccacaagtat tagtgagtct tccttattaa    660
tattttcatt tcagaagact gaagcaaagc tgatagtgtt tgctgtttct ttggcagcta    720
agtgagggtc ttgggatgac ttgctgtgtt cctcaagctg cactttgggg ccatctctgc    780
agtattaagc cccctttttg cttggtggta ctctgtctgt gcctgtgtgt gtgtgtgata    840
gtcactcttg catggcttcc atgtctggtt tgtggcattt ggggataagt gctgaaccag    900
agcatttgca gtttgtttga ggcctcgttg ccaatgatag atcactcctg ttgacctggt    960
atgtctgctt gcttgctgct tttccttgct ttctcttgga agaggaaagg actctggtca   1020
ggcccaggct gagtgagatg agctgcagct ggctcatggc cttcttagag cagagagagg   1080
agtatgtcat tttactaagt tcctaaacaa acatttatgc aggcaacact ccttgcagat   1140
ccagaaactg aggcacaata gggttatgac ttgctcaaga atatgtagct gctagggggt   1200
aaatcaaggc atcacaattt ctgttcagcg ggcaggaata ggctgtgaat tgctagcact   1260
ttttttttaa gcaattactt tttgacttgt tcctctgaaa gtgcaagagg cgtacacctt   1320
tcccaaatgt agactagaat ctgcaggatg ccacccactg tatagttctg ctttcccaga   1380
gaggaagaac ttttagaaac caaatgatct taattgttat tgcccacccc tggcttttcc   1440
gggtagaaaa ttcacagtag gaatgattgt taagagagag tgcttggaac catgggttaa   1500
caggaaaggc tacctaactt cacatatctg caaccagagc agccaccaag cattacttag   1560
cagcaggaaa atgattgtat ttgagttcct gtgtgtccaa aactgaggca ccatgttctt   1620
tgaaaacatg ccacctcaag gctgggcgcg gtggctcaca cctgttaatc ccagcacttt   1680
gggaggccga ggcgggcgga tcaccggagt cggggagttt gagaccagcc tggaccaaca   1740
tgggagaaac cccatctcta cctaaaaata caaaattagc cgggcgtggt ggcatgcgcc   1800
tataatctca gctacttggg agggytgagg caggrgaatt gcttgaaccc rgganggcgg   1860
aggtttgcgg ttgagttgag gatcgtgcca ttgcacttcc gggccttggg gcaacaacag   1920
caaaaaytcc gtcttcaamw mrtgccgaat tcgatatcaa gcttatcgat accgtcgacc   1980
tcgagggggg gcccggtacc caattcgccc tatagngatc gtattacaat c            2031

<210> 83
<211> 1153
<212> DNA
<213> Homo sapiens

<400> 83
ggcacagagc ctccgaccca ggtggtctgg agcctgccgg gagagtggtg gcatctgaga     60
ggctggtcgt ggactgtggt tgggggaggt gggagctgtt ttaaccgtgt gccccctctc    120
ctgtgccggc gtgggcatcc cccggggcag tggaacccgg gcgctcctcc agcttccgag    180
tccagccagc ctgggcgcgg ggcgcgcccc gagacacccg aggagtccgt tcctccctgg    240
ttacgtggac tgtggagctg gtctcttgtg gctcagcgcc gtgcggaggt tgaagcgtac    300
ctgcggaggt cgcaccaggg cgtgaggagg aggaggaagg gcatgagccg agcttgagga    360
atccgtgctc caaactctac actcaaggat gcactgcgca actctggtgg cgatgggctg    420
gggcagatgt ccttggagtt ctaccagaag aagaagtctc gctggccatt ctcagacgag    480
tgcatcccat gggaagtgtg gacggtcaag gtgcatgtgg tagccctggc cacggagcag    540
gagcggcaga tctgccggga gaaggtgggt gagaaactct gcgagaagat catcaacatc    600
gtggaggtga tgaatcggca tgagtacttg cccaagatgc ccacacagtc ggaggtggat    660
aacgtgtttg acacaggctt gcgggacgtg cagccctacc tgtacaagat ctccttccag    720
atcactgatg ccctgggcac ctcagtcacc accaccatgc gcaggctcat caaagacacc    780
ctgccctctg agcgtcgctg gatctctggg agctccttga tggctcccag accttggctt    840
ttgggaattg cacttttggg cctttgggct ctggaacctg ctctgggtca ttggtgagac    900
ttggaagggg cagcccccgc tggcttcttg gttttgtggt tgccagcctc aggtcatcct    960
tttaatcttt gctgacggtt cagtcctgcc tctactgtct ctccatagcc ctggtggggt   1020
cccccttctt tctccactgt acagaagagc caccactggg atggggaata aagttgagaa   1080
catgagtttg ggctgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1140
aaaaaaaaaa aaa                                                      1153

<210> 84
<211> 1346
<212> DNA
<213> Homo sapiens

<400> 84
ggcacgaggc gcctaccctg cctgcaggtg agcagtggtg tgtgagagcc aggcgtccct     60
ctgcctgccc actcagtggc aacacccggg agctgttttg tcctttgtgg agcctcagca    120
gttccctctt tcagaactca ctgccaagag ccctgaacag gagccaccat gcagtgcttc    180
agcttcatta agaccatgat gatcctcttc aatttgctca tctttctgtg tggtgcagcc    240
ctgttggcag tgggcatctg ggtgtcaatc gatggggcat cctttctgaa gatcttcggg    300
ccactgtcgt ccagtgccat gcagtttgtc aacgtgggct acctcatcgc agccggcgtt    360
gtggtctttg ctcttggttt cctgggctgc tatggtgcta agactgagag caagtgtgcc    420
ctcgtgacgt tcttcttcat cctcctcctc atcttcattg ctgaggttgc agctgctgtg    480
gtcgccttgg tgtacaccac aatggctgag cacttcctga cgttgctggt agtgcctgcc    540
atcaagaaag attatggttc ccaggaagac ttcactcaag tgtggaacac caccatgaaa    600
gggctcaagt gctgtggctt caccaactat acggattttg aggactcacc ctacttcaaa    660
gagaacagtg cctttccccc attctgttgc aatgacaacg tcaccaacac agccaatgaa    720
acctgcacca agcaaaaggc tcacgaccaa aaagtagagg gttgcttcaa tcagcttttg    780
tatgacatcc gaactaatgc agtcaccgtg ggtggtgtgg cagctggaat tgggggcctc    840
gagctggctg ccatgattgt gtccatgtat ctgtactgca atctacaata agtccacttc    900
tgcctctgcc actactgctg ccacatggga actgtgaaga ggcaccctgg caagcagcag    960
tgattggggg aggggacagg atctaacaat gtcacttggg ccagaatgga cctgcccttt   1020
ctgctccaga cttggggcta gatagggacc actcctttta ggcgatgcct gactttcctt   1080
ccattggtgg gtggatgggt ggggggcatt ccagagcctc taaggtagcc agttctgttg   1140
cccattcccc cagtctatta aacccttgat atgcccccta ggcctagtgg tgatcccagt   1200
gctctactgg gggatgagag aaaggcattt tatagcctgg gcataagtga aatcagcaga   1260
gcctctgggt ggatgtgtag aaggcacttc aaaatgcata aacctgttac aatgttaaaa   1320
aaaaaaaaaa aaaaaaaaaa aaaaaa                                        1346

<210> 85
<211> 1019
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (949)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (968)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (974)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1003)
<223> n equals a,t,g, or c

<400> 85
ggcacagcag cggcggtcgc ggctgaggct gaggaggagg cggcggcggc gggcggggct     60
cggctcgggc tccgcgggcg ggcgggcgga catggcggcc aacatgtacc gggtcggaga    120
ttatgtctac tttgagaatt cctccagcaa cccataccta ataagaagga tagaagaact    180
caacaagact gcaatggcaa cgtggaagca aaagtagtat gcttttatag acgacgtgat    240
atttccaaca cacttataat gctcgcagat aagcatgcta aagaaattga ggaagaatct    300
gaaacaacag ttgaggctga cttgaccgat aagcagaaac atcagttgaa acatagggaa    360
ctctttttgt cacgccagta tgaatctctg cccgcaacac atatcagggg aaagtgcagt    420
gttgcccttc tgaatgagac agaatcagta ttgtcatatc ttgataagga ggataccttc    480
ttctactcat tggtctatga cccctcattg aaaacactat tagctgacaa aggtgaaatc    540
agagtgggac ctagatatca agcagacatt ccagaaatgc tgttagaagg agaatcagat    600
gagagggaac aatcaaaatt ggaagttaaa gtttgggatc caaatagccc acttacggat    660
cgacagattg accagttttt agttgtagca cgtgctgttg ggacattcgc cagagccctg    720
gattgcagca gttctgtgag gcagcctagt ttgcatatga gtgctgctgc agcttcccga    780
gacatcacct tgtttcacgc tatggataca ttgtatagac acagytakga tttgagcagt    840
gccattagtg tcttagtacc actcggagga cctgttttat gcagagatga aatggaggaa    900
tggtcagcct ctgaagctag cttatttgaa gaggcctgga aaattggcna agacttcaat    960
gacatacngc agantttctt ccttggaatc attgactagc acnttgatat attactgtg    1019

<210> 86
<211> 1540
<212> DNA
<213> Homo sapiens

<400> 86
cccacgcgtc cggaaggatt gaccagttaa ccaacatctt agcccccatg gctgttggcc     60
agattatgac atttggctcc ccagtcatcg gctgtggctt tatttcggga tggaacttgg    120
tatccatgtg cgtggagtac gtcctgctct ggaaggttta ccagaaaacc ccagctctag    180
ctgtgaaagc tggtcttaaa gaagaggaaa ctgaattgaa acagctgaat ttacacaaag    240
atactgagcc aaaacccctg gagggaactc atctaatggg tgtgaaagac tctaacatcc    300
atgagcttga acatgagcaa gagcctactt gtgcctccca gatggctgag cccttccgta    360
ccttccgaga tggatgggtc tcctactaca accagcctgt gtttctggct ggcatgggtc    420
ttgctttcct ttatatgact gtcctgggct ttgactgcat caccacaggg tacgcctaca    480
ctcagggact gagtgggttc catcctcagt attttgatgg gagcatcagc tataactgga    540
ataatgggaa ctgtagcttt tacttggcta cgtcgaaaat gtggtttggt tcggcaggtc    600
tgatctcagg attggcacag ctttcctgtt tgatcttgtg tgtgatctct gtattcatgc    660
ctggaagccc cctggacttg tccgtttctc cttttgaaga tatccgatca aggttcattc    720
aaggagagtc aattacacct accaagatac ctgaaattac aactgaaata tacatgtcta    780
atgggtctaa ttctgctaat attgtcccgg agacaagtcc tgaatctgtg cccataatct    840
ctgtcagtct gctgtttgca ggcgtcattg ctgctagaat cggtctttgg tcctttgatt    900
taactgtgac acagttgctg caagaaaatg taattgaatc tgaaagaggc attataaatg    960
gtgtacagaa ctccatgaac tatcttcttg atcttctgca tttcatcatg gtcatcctgg   1020
ctccaaatcc tgaagctttt ggcttgctcg tattgatttc agtctccttt gtggcaatgg   1080
gccacattat gtatttccga tttgcccaaa atactctggg aaacaagctc tttgcttgcg   1140
gtcctgatgc aaaagaagtt aggaaggaaa atcaagcaaa tacatctgtt gtttgagaca   1200
gtttaactgt tgctatcctg ttactagatt atatagagca catgtgctta ttttgtactg   1260
cagaattcca ataaatggct gggtgttttg ctctgttttt accacagctg tgccttgaga   1320
actaaaagct gtttaggaaa cctaagtcag cagaaattaa ctggattaat ttcccttatg   1380
ttgagggcca tggraaaaaa attgggaaaa ggaaaaactc agttttaaat acgggagact   1440
ataatggata acactgratt cccctatttc tcatgagtag atacaatctt acgtaaaaga   1500
gtggttagtc acgtgaattc agttatcatt tgacagattc                         1540

<210> 87
<211> 624
<212> DNA
<213> Homo sapiens

<400> 87
ggcacgaggg tgtggtagcc ggcgccgcgc ccatagccgg acggggatct gagctggcag     60
gatgaatgtg ggggtggcac acagcgaagt aaaccccaac acccgagtga tgaatagccg    120
aggcatctgg ctggcctaca tcatcttggt aggattgctg catatggttc tactcagcat    180
ccccttcttc agcattcctg ttgtctggac cctgaccaac gtcatccata acctggctac    240
gtatgtcttc cttcatacgg tgaaagggac accctttgag actcctgacc aaggaaaggc    300
tcggctactg acacactggg agcaaatgga ctatgggctc cagtttacct cttcccgcaa    360
gttcctcagc atctctccta ttgtgctcta tctcctggcc agcttctata ccaagtatga    420
tgctgcgcac ttcctcatca acacagcctc attgctaagt gtactgctgc cgaagttgcc    480
ccagttccat ggggttcgtg tctttggcat caacaaatac tgagggatgg gttttgggac    540
agctccatgg gcatggggaa ggcactgaaa cagaggacta taaaacatcc ttctcttatt    600
ctccaaaaaa aaaaaaaaaa aaaa                                           624

<210> 88
<211> 646
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (523)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (611)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (631)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (635)
<223> n equals a,t,g, or c

<400> 88
gcctgtcatg cctatngcct agctgccaga ttaaccttgc cttgaaaata acgattgccc     60
cataggctat tcagtgtaag gaagacaaaa attccttggg aacctactag tgggtttgcc    120
ttccagattt ggtagacgca aaaagcaaag ggggaacatg ggcaaaggaa gatttgatga    180
aaaagaaaat gtgtccaact gcatccagtt gaaaacttca gttattaagg gtattaagaa    240
tcaattgata gagcaatttc caggtattga accatggctt aatcaaatca tgcctaagaa    300
agatcctgtc aaaatagtcc gatgccatga acatatagra atccttacag taaatggaga    360
attactcttt tttagacaaa gagaagggcc tttttatcca accctaagat tacttcacaa    420
atatcctttt atcctgccac accagcagtt tgataaaggg agccatcaaa tttgtactca    480
gttggagcaa atatcatgtt tcccaggctt acttctcctg gancttaact ttacccctgc    540
tgcagtaaat accattgttt gctatcattg gccaaaaagg aaaacagcat gcctattttt    600
tgggaatccn naaaattttt tgcaaaaaaa nttanaaaat ttcccc                   646

<210> 89
<211> 368
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (321)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (350)
<223> n equals a,t,g, or c

<400> 89
aattcggcag agctggcatg gcccaaatag tattattctc actttttcct gtttctatag     60
accctgtcag ggagggtaaa ttaaascaaa gtccctcctt aggaaaaagc agctgggtct    120
taagtagaaa sctgctctca ggctgggatt acaggcatga gccaccgtgc ccagccgatw    180
aatgcctttt aaagctggga atttttttac ccaatctggg rttcagtcaa aggccataca    240
ttgcatattg ttgtcttgtc tctagtctcc tccagaacag ttacctgtgt attttttttg    300
tctttaatga tgttttgaag ngtccaggct agttgtttta cagaatttcn ggttttggac    360
agaaatcc                                                             368

<210> 90
<211> 527
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (495)
<223> n equals a,t,g, or c

<400> 90
ttnttttttt ttcttcattt tcctagcaac ctcactaagg ctgggaggag gagaataatc     60
ttccatgtca gaatctgacg gacttcggtt tcgataacga ccaccacctg aactccttct    120
tccttcatga gagtggccac ttctcctatg atccccagag cttcttctgt cacgctcttc    180
atattcccaa gctttatcat catctttttt atgtcgtttc ctagaggatt caaaagcttc    240
atcactatca ttatcttcat ctgaactgat ttcagcatat tttggctttt cattaactgt    300
gtacgcttgc gtttgttcat tttcacacgt tcacaaagtg gcatggtgga ctcaatttct    360
gccaggagtt cagggggtaa ttcttttaac actgattgat ctatactacc tttatttgac    420
tttgatggtt tattcttgat aggtttaagg gaacttcttg atttgtcctc tctatcttta    480
ataagtttct gaacntcatc caaagacagt ttttgtagca caactac                  527

<210> 91
<211> 395
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (335)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (365)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (377)
<223> n equals a,t,g, or c

<400> 91
gaagagggct ataagggcag cggcccaggc gggcgggatc caggcgggcc atggcggatg     60
tccccggggc acagcgagcg gttcctggtg acggcccaga gccccgggac cccctggact    120
gttgggcctg cgctgttctt gtaacagccc agaatctgct ggtggctgcc ttcaatcttc    180
tcctgctggt gctggtgcta gggaccatct tgctacccgc tgtcaccatg ctgggcttcg    240
gcttcctctg ccactctcag ttcctgcgct cccagggcac ccccttgcac cgcgcacctg    300
cggaaccccg gttttcacgg gccctactgg ttcancggat ttcctggttc cttcgtggcc    360
gttgnttcgt ggtttgnttt tgggccaagt taacc                               395

<210> 92
<211> 1088
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (962)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (995)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1055)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1060)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1068)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1081)
<223> n equals a,t,g, or c

<400> 92
atccaaagaa ccgcgagtgc ttgctctctg ctcctcggaa gaaacttaac catcttttga     60
aagcccttga aacgtcaaag gcagatctgg agtcacttct gcagacaccg ggtgggaagc    120
ctcgtggctt cagtgaagca gctgccccgc gagcctttgg tctccactgt cgcctgagca    180
tccatcttca gcacaagttc tgctcagaag gaaaggtgta tttgtccatg ttggaagaca    240
ctggcttttg gttagaaagc aaaattttat cttttattca agatcaagaa gaagactacc    300
tgaagcttca tagggtcatt tatcagcaaa ttatccagac ctacctgact gtgtgtaaag    360
atgttgttat ggtaggcctt ggtgaccatc agtttcagat gcaactctta cagcggagtc    420
ttggaatcat gcaaacagtg aagggrtttt tttatgtttc attacttctt gacattctga    480
aagagataac tggaagttcc ttgattcaga aaacagattc agatgaagaa gttgcaatgc    540
tgttggacac agtccagraa gtatttcaga aaatgttgga atgtattgca cggagcttca    600
ggaagcagcc ggaagaaggc ctgcggtgct ttattctgtt cagaggcctc ttcatgagtt    660
cattactgct gttcagtctc ggcacacaga cacccctgtg caccggggtg tactttctac    720
tctgatcgct gggcctgtgg ttgagataag tcaccagcta cggaaggttt ctgacgtaga    780
agagcttacc cctccagagc atctttctga tcttccacca ttttcaaggt gtttaatagg    840
aataataata aagtcttcga atgtggtcag gtcatttttg gatgaattaa aggcatgtgt    900
ggcttctaat gatattgaag gcattgtgtg cctcacggct gctgtgatat tatcctggtt    960
antaatgcag gtaaacataa aagctcaaaa gtganggagg ttgcaagcac tgtcacagaa   1020
actaaagcat ccatggaaat accttggaga gatancttgn aagattcnct agaaccacca   1080
ncagacct                                                            1088

<210> 93
<211> 542
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (85)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (210)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (262)
<223> n equals a,t,g, or c

<400> 93
cncaggttcg ggaccaccgc agcttggggt ggcagcggcg caggaggggt cgcggggagg     60
gagtggactg accagggcca agtgncgctc gggggcacta catggcggag ggtgaagggt    120
acttcgccat gtctgaggac gagctggcct gcagcccata catcccccta ggcggcgact    180
tcggcggcgg cgacttcggc ggcggcgacn ttcggcggcg gcgacttcgg cggcggcgac    240
tttcggcggt ggcggcagtt cnggtgggca ttgcttggac tattgcgaaa ccctacggcg    300
cactgcaatg tgctgaactg ggagcaagtg cagcggctgg acggcatcct gagcgagacc    360
attccgattc acgggygcgg caacttcccc acgctcgagc tgcagccgag cctgatcgtg    420
aaggtggtgc ggcggcgcct ggccgagaag cgcatyggcg tccgcgactg cgcctcaacg    480
gctcggcagc cagccatgtc ctgcaccagg acagcggcct gggctacaag gactggacct    540
ca                                                                   542

<210> 94
<211> 880
<212> DNA
<213> Homo sapiens

<400> 94
ttatccgctg gctcctgttt ccaattgatt gagggatgcc cccaaggaag ttaacttcac     60
tgcaattctg agctgtaatt gactttaata agctccaaca gcactgaaag acgtttggat    120
tattttcagt ttgggataat actactatga acattcctgt acatgtcttt tgagaacacg    180
catgtgtaca tttgtgatgg gtatgtaatg gggtggaatt actggttcat agaatatgtg    240
catattcacc tttagatata gaggctgcca accatttttc traagtgatt atactaattt    300
atattctcac tatctgtaaa tgaacatttc tgttgctcca catccttgct ggcacttggt    360
attgattgat ttctctttta attttaggct ttttaatacg tgtgtagtga tatctcactt    420
gctgtttgtt tgctttttgg taaatttttt attgaagtat aatttacata cagaaaatca    480
cacaaattgt gtacaggtgt gatttttcac accgtgaata catgcaaaaa ctagtatgaa    540
attaagagtt ggaacatcac cagtactcca gaagccccat gcatgttctc ttccagttac    600
tataccacta tcccaaggat ggtctattaa ttcaacagca tagatttatt ttgcctgttt    660
ttcaacttca aataaatgaa ataatatgca ctcttgtgtc tggcttcttt gactcaacag    720
tatgtctata caactcatct gtattgttgc atgttgtagt tcgttcattc atactgttgt    780
atacagtatt gaattgtata aattactcat tctgttacta tgcatttggg ctgtttccag    840
ttttggctat tatgaataaa gctgctatga acattctagg                          880

<210> 95
<211> 627
<212> DNA
<213> Homo sapiens

<400> 95
cagcgaatcc tcaagcataa catggacttt gggaagtgcc cgcgactgag gctgtttact     60
caggagtaca tccttgcctt gaacgagctc aacgcgggga tggaagtggt gaagaagttc    120
attcagagca tgcacggccc cacagggcac tgcccccacc cccgggtcct gcccaacctg    180
gtggccgtgt gcctggctgc catctactcc tgctatgaag agttcatcaa cagccgcgac    240
aattccccaa gcctgaagga aatccggaac ggctgccagc agcgtgcgac cggaagccca    300
ctttacctct gcgccttctg caccccagcc cggacctggt gtctcaggaa gccacgctgt    360
ctgaggcccg gctcaagtcg gtggtcgtgg cctccagtga gatccacgtg gaggtggaac    420
gcaccarcac tgccaagccg gcgstgacgg ccarcgcagg caacgacagc gagcccaacc    480
tcatcgactg cctcatggtc agccccgcct gcagcaccat gagcatcgag ctgggccccc    540
aggccgaccg cacgctcggc tgctacgtgg aaatcctcaa gctgctgtca gactatgatg    600
actggagacc gtctctgggc cagtttg                                        627

<210> 96
<211> 1071
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1010)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1048)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1062)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1066)
<223> n equals a,t,g, or c

<400> 96
ggcaggaggc tgccggggcg cgggctgctg cgggagaagg ggctccgagg agtccgccgc     60
ggctcgctct gtcgccggcg cgggattggg gcgcgagggc catgggcgcg ctctcctaag    120
gcggaggtcg cgggcgggag gggaggaggc ccgagagagg ctgctgcgaa ggccgcgggc    180
ccgtgactgg gcgcgaggcg gccggcggcg gcggcggcac cagcaccacc atgtcgcgct    240
cagtgctgca gcccagtcag cagaagctgg cggagaagct caccatcctc aacgaccggg    300
gcgtcggcat gctcacccgc ctctacaaca tcaagaaggc atgtggagac cccaaggcaa    360
aaccatccta tcttatcgac aaaaacctgg aatctgctgt gaaattcata gtcagaaaat    420
tccctgctgt agaaacccgc aacaacaatc aacagcttgc acaactacag aaagaaaaat    480
cagagattct gaaaaatctg gcattatatt acttcacatt tgtagatgtt atggaattta    540
aggaccatgt ttgtgaattg ctgaatacta ttgacgtttg ccaagtcttc tttgatatta    600
ctgtaaactt tgatttaaca aagaactact tagatttaat tataacctat acaacactaa    660
tgatactgct gtctcgaatt gaagaaagga aggcaatcat tggattatac aactatgccc    720
atgaaatgac tcatggagca agtgacagag aatacccacg ccttggccag atgattgtgg    780
attatgaaaa ccctttaaag aagatgatgg aagaatttgt accccatagc aagtctcttt    840
cagatgcact aatttctctt caaatggtat atcctcgaag gaatctttca gctgaccagt    900
ggagaaatgc ccagttattg agcctcatca gtgcacctag tacaatgctt aatccagcac    960
agtccgacac tatgccttgt gaatacctct ctttgggatg caatgggaan attggattat   1020
ctttggcttt atttgtgcca tggggatnct taaatacttg angctncagt a            1071

<210> 97
<211> 539
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (509)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (518)
<223> n equals a,t,g, or c

<400> 97
ggcacgagta actcagtgct tggacacttg gaaaacatgc accctgataa ctcaaaggca     60
cctggcttca gaccaccttc ccagcgagtt tctactagtc cagttgggtt accatccatt    120
gacccatcag gcagctcccc atcttcctct tctgctcctc tggcaagttt ttccggcata    180
ccaggaacaa gggttttcct gcaaggccag ctcctgttgg gactcctagt ttcaacagac    240
aacatttttc tccccatcct tggacaagcg cctcaaactc atccacttct gccccaccaa    300
cgttgggcca accaaaagga gtcagtgcca gtcaagatcg aaagatacct cccccaattg    360
gaacagagag actggcccga attcggcaag gagggtctgt tgcacaagcc ccggcggggg    420
accagttttg tcgctcccgt tgggacacag tgggaatctg gttcatttgg tgttcaatgc    480
tgtgtaraag ggttwatagg ktggggcana ctgtggangg gggaaccatc caatggcat     539

<210> 98
<211> 827
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (418)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (484)
<223> n equals a,t,g, or c

<400> 98
acaaagaatc aactttattg aacattcagg gtcagtttct cttcttgctc ttgcctgtga     60
ccttggctgg tgtgaggact ggagctgctg cctggtacag ggtggaggag atcttgttga    120
tgtagtacag accaaccatg gagaagatga agcaggtggt gacacagact cggtggatga    180
ggccagatgc aaagagagcc aacaggaggc acaggagaat ctcagggaag atctttgctt    240
ggaatccttt gccaaagaca agattctcca gattattgaa ggcagtgagc gagaacacga    300
agagacccga accaagcagg ccgccctgga tggtgagcca ctcggtggag gccagctgac    360
ggctgtacat ctgcatccca gcaaagagca gcagggacag gagggaggag agcgccangm    420
gaggtgcccg tacccaccac tggaggggat gggagaaggg acggagagtc agctccgccy    480
tccntccggc aagctacggg cagatcagcc ggtccggaag ctcggtgggc cgaccccctc    540
caagaactcc cgggactgca gccacacgcc ccaactcccc acaccgcgcg gcaaccccta    600
cgtattcccc agccccggac accccgaacc ctcccgtccg gtggaaatgc ccgctcccgg    660
tggaacccag gacacgtcag ctctgtcggg agaggacgag gaaagcttgt ccacccaaac    720
cccgaccccc tctaggactt cctggggacc ccaccggtcc tgttacccat catgccccgc    780
ccgtgagtcc aaccggcgcc tctggccaag aaaggccgga cgcgtgg                  827

<210> 99
<211> 1538
<212> DNA
<213> Homo sapiens

<400> 99
aattcggcac gagcaaattt atacaagctt tttctaggga caccggtgct atgcaatttc     60
tggaaaatta tgaaaaagaa gacataacag tagcagaact ggaaggaaac tcaaattctt    120
tgtggaccat cagcccaccc agtaagcaga aaatgataca cgaactcctg gaccccaata    180
gtagcttctc tgttgttttt tcatggagta ttcagagaaa cttaagtctg ggtgcaaaat    240
cggaaatagc aacagataag ctttcttttc ctcttaaaaa tattactcga aagaatatcg    300
ctaaaatgat agcaggcaac agcacagaaa gttcaaaaac accagtgacc atagraaagr    360
tttatccmta ttatgtgaaa gcacctagtg rttctaactc aaaacctata aagcaacttt    420
tatctgaaaa taatttcatg grtattacca tcattttgtc cagagacaat acaactaaat    480
ataacagtga gtggtgggtt ctcaacctga ctggaaacag aatatacaat ccgaactctc    540
aggccctgga actggtggtc ttcaatgaca aagtcagtcc cccaagtctg gggttcctgg    600
ctggctatgg tattatggga ttatatgctt cagttgtcct tgtgattggg aaatttgtcc    660
gtgaattctt cagtgggatt tctcactcca tcatgtttga agagcttcca aatgtggatc    720
gaattttgaa gttgtgcaca gatatttttt tagttcgaga gacaggagaa ctggagctag    780
aagaagatct ctatgccaaa ttaatattcc tatatcgctc accagagaca atgatcaaat    840
ggactagaga aaaaacaaat tgaaacctta gaacacagac tgcaaataat gttaacattt    900
gaattttttt taaaagcaca atattctcat aagagctaag catttctagt tcgacggaaa    960
tggtttgttt ctcttctgat aggtagacaa aaggagctga tatccttctg cagtaaaagc   1020
taccttgcaa gttaaggcac tgttgaaaat gttatttgta actccatttc tctgaaatca   1080
gggctacttg ctttatgttt tagtcaacag tgtctcgcat tctgattgat catgtgaagg   1140
aatcatttat gggccccgtc cctaagagaa acagaagagg agtcagaaag aaagatgcct   1200
gtgttttcct ctgtggggcc cgtgcacttc ctggagagat gctacaatgc aatatacagc   1260
gctccatccc actggggaag ctgctgtgat gagactagat gagccttcaa cacactcaga   1320
aaatgcaaca gcaatagggg gcagacagct cctacctgtg tttctaggag caaaagagag   1380
ggaactaatt gcccgtgaag acgccagtgg aaggatcagc ctcattctaa gcaaaaacat   1440
agtattagtg atactcttac tgccttatct taaccaagga ctaataggat acctttccat   1500
taaacaccag tgacttctca ggaaaaaaaa aaaaaaag                           1538

<210> 100
<211> 480
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (450)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (475)
<223> n equals a,t,g, or c

<400> 100
gacagcgctg gcactgggga cctctcttac ggttaccagg gccgctcctt tgaacctgta     60
ggtactcggc cccgagtgga ctccatgagc tctgtggagg aggatgacta cgacacattg    120
accgacatcg attccgacaa gaatgtcatt cgcaccaagc aatacctcta tgtggctgac    180
ctggcacgga aggacaagcg tgttctgcgg aaaaagtacc agatctactt ctggaacatt    240
gccaccattg ctgtcttcta tgcccttcct gtggtgcagc tggtgatcac ctaccagacg    300
gtggtgaatg tcacagggaa tcaggacatc tgctactaca acttcctctg mgcccaccca    360
ctgggacaat ctcagcgcct tacaacaaca tcctcagcaa cctggggtac atcctgctgg    420
ggctgctttt ctgctcatca accttgcaan ggggagatca accaaaaacc ggggncctgg    480

<210> 101
<211> 1170
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<400> 101
acacgcacag tcacncctta cacatagccc tagcccagtg gtcctcaaag tgtgacccat     60
agactaatag catagcatta cctgagaact tgataatgca tatttgcagg ccccacgcaa    120
aacctgctga atcagaagct ctgagagtaa ggcctaccaa tctggtttaa caagcccgtc    180
aggtgattct gatttacagt acagtttgag acccactggc tagaacatat cctccagaga    240
cttggcttaa ttggtctggg taaatatggc tgagcgttgt tatcttttgt tatcttttat    300
atgccctagg aaagtacaac cagaattgaa aaccaactga tctataccag ttctttcaat    360
taatagtcaa gaacattgag tccagtgaga ttaagtgatt tttgcaggct atgaggtttt    420
atgctattcc tgtgttctcc aaaacaagaa aataaaaaga catgacttat tctctgttca    480
tacagcaagt atggaaaaaa gatgatctag aagtcaacta tctcaacctc cattgttacc    540
cactaggttt ttttctaata atgttaaagg ctatttaatt tatttaatca actttaagca    600
ttacattctc aattggggac aaaaattggt tcttggggtg aaaaaatatt agatatggct    660
tgtggacttc caatatcatc ctatccaaca aaatcytatt ccytagtatt aatttatctc    720
attgggaaga aatttgtagt taaaactaat ataatttgaa tttaatttct gtaattggga    780
aggagggtaa taatgaacaa aaagtttgag aaaaaaatgc tttaatgggt tttacaggca    840
tgctacaatc caggactgtg gtgttctatg tgccgtgtat ggtcatatta gtagctattt    900
gttgcaagat acttgaagcc aaatgtttgc agtataggtt cctggctact gtttatgctg    960
tgatttcact ctgtctatca tgggcagtat tagaaaacac actggttttc actatctggt   1020
ttacaaacac tatcattatt ttacctggat tgaagtgcag aatttggcat atcgatgcat   1080
gcaatggaaa gaaaaaaaat ttgttaaaat ttgtaaatgt tcagctaaat ctcagatata   1140
ctgtgggatg agtatctcag ggtaagtaac                                    1170

<210> 102
<211> 639
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (573)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (625)
<223> n equals a,t,g, or c

<400> 102
aattcggcac agtgggcacg gactactggt tatattccag aggtgtgtgc aggactaaat     60
ctacaagtga taatgaaacc agcaggaaga atgaagaagt aatgacccat tcggggctgt    120
ggaggacctg ctgcctagaa ggggctttcc gaggcgtgtg caagaaaatc gatcacttcc    180
ctgaagatgc tgactacgaa caggacacag ccgaatatct cctgcgagct gtgagggcct    240
ccagtgtctt ccccatcctc agtgtcacgc tgctgttctt cggcgggctc tgcgtggcag    300
ccagtgagtt ccaccgcagc agacacaacg tcattctcag cgcgggcatc ttttttgtct    360
ctgcagggtt aagcaacatc attggcatca tagtttatat atcagccaac gccggagacc    420
ccggggcagc gtggaytcca aaaaaagtta ytcctatggt tggtcctttt attttcggga    480
gccttctctt tcatcatcgg caggaaattt gttagggagt gggtttgccg tggcacatct    540
attatttgaa aaaacattca ggcagtttac ggngccaaat tcccattcgg agtttcctgg    600
aggaaatctt actttttggc cccgncttcc caccttaca                           639

<210> 103
<211> 545
<212> DNA
<213> Homo sapiens

<400> 103
tggaattatt ccaccgcctt ccagttgtaa tgtacccaga cagatacagg caaaatatct     60
gaaaggaagg acaatcattg gcgttgcagc aggcaggttt catacagtcc tatggctaga    120
gaagctgttt acactatggg actaaatggt ggacaactgg gttgtttgct agatcccaat    180
ggagaaaagt gtgtaactgc tcctcgtcag gtctctgccc ttcaccataa agacattgct    240
ctgtctttgg ttgctgcaag tgatggagct acagtctgtg ttaccacaag gggagatatt    300
tacttacttg cagactatca gtgcaagaag atggcttcta aacagttgaa cttgaaaaaa    360
gttcttgtgt ctgggggtca tatggaatac aaggttgatc ctgaacattt gaaagaaaat    420
gggggtcaaa aaatttgcat tcttgcaatg gatggagctg gaagggtgtt ttgctggaga    480
wcagtcaaca gttctctkaa gcagtgtcga tgggcctacc acgtcaggtc ttcatttctg    540
atatt                                                                545

<210> 104
<211> 1579
<212> DNA
<213> Homo sapiens

<400> 104
taatccagaa tagttttagt gaaccgtagt tactctggcc aggtgcacgt ctaactagat     60
tagatgttgt ttgaaacatc tacatccacc atttgttatg cagtgttccc aaatttctgt    120
tctacaagca tgttgtgtgg cagaaaactg gagaccaggc atcttaattt tacttcagcc    180
atcgtaccct cttctgactg atggacccgt catcacaaag gtccctctca tcatgttcca    240
gtgagaggcc agcgattgct ttcttcctgg catagtaaac attttcttgg aacatatgtt    300
tcacttaatc actaccaaat atctggaaga cctgtcttac tcagacagca ccaggtgtac    360
agaagcagca gacaagatct tccagatcag cagggagacc ccggagcctc tgcttctcct    420
acactggcat gctgatgaga tcgtgacatg cccacattgg cttcttccac atctggttgc    480
actcgtcatg atgggctcgc tgcatctccc tcagtcccaa attctagagc caagtgttcc    540
tgcagaggct gtctatgtgt cctggctgcc caaggacact cctgcagagc catttttggg    600
taaggaacac ttacaaagaa ggcattgatc ttgtgtctga ggctcagagc ccttttgata    660
ggcttctgag tcatatataa agacattcaa gccaagatgc tccaactgca aatataccaa    720
ccttctctga attatatttt gcttatttat atttcttttc tttttttcta aagtatggct    780
ctgaatagaa tgcacatttt ccattgaact ggatgcattt catttagcca atccagtaat    840
ttatttatat taatctatac ataatatgtt tcctcagcat aggagctatg attcattaat    900
taaaagtgga gtcaaaacgc taaatgcaat gtttgttgtg tattttcatt acacaaactt    960
aatttgtctt gttaaataag tacagtggat cttggagtgg gatttcttgg taaattatct   1020
tgcacttgaa tgtctcatga ttacatatga aatcgctttg acatatcttt agacagaaaa   1080
aagtagctga gtgaggggga aattatagag ctgtgtgact ttagggagta ggttgaacca   1140
ggtgattacc taaaattcct tccagttcaa aggcagataa atctgtaaat tattttatcc   1200
tatctaccat ttcttaagaa gacattactc caaaataatt aaatttaagg ctttatcagg   1260
tctgcatata gaatcttaaa tyctaataaa gtttcatgtt aatgtcatag gatttttaaa   1320
agagctatag gtaatttctg tataatatgt gtatattaaa atgtaattga tttcagttga   1380
aagtatttta aagctgataa atagcattag ggttctttgc aatgtggtat ctagctgtat   1440
tattggtttt atttacttta aacattttga aaagcttata ctggcagcct agaaaaacaa   1500
acaattaatg tatctttatg tccctggcac atgaataaac tttgctgtgg tttactaaaa   1560
aaaaaaaaaa aaaactcga                                                1579

<210> 105
<211> 524
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (466)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (477)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (484)
<223> n equals a,t,g, or c

<400> 105
ggccatgtga tgctaggaac aatggatgtc catcaccact ggacaaaaac tgttgaaaag     60
tagaatacta tttcaccctc gaagtttgcg tggtttacaa atgatcctta acagtgacag    120
atatgctcca agcttgcatg aactcgggca ttttaatatt ccaacactct gtgatccagc    180
aaatctccag tggtttattc tcaccaaagc tcagcaggca agagagaaca tgaaaagaaa    240
ggaagagtta aaggttattg aaaatgaatt gatacaggca tcaacaaaga aattttcttt    300
ggagaagtta tataaagagc ccagcattct agtatacaaa tggtggattg ttgtaagagc    360
tctagaacaa cactgccttc ctacatggga tgcactctgc atttacattt ttctctgtta    420
tgcaagatgg agactttgta tccttggaat tggaagaatg gagaancatt aagtacncag    480
aaantgtttt atttttagag atagaaggac ttaattaaaa tatt                     524

<210> 106
<211> 713
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (596)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (668)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (677)
<223> n equals a,t,g, or c

<400> 106
ggaggtgaag aatcagacaa agaaaaacag gaaatgtttg cagttcattc tgtcaacttg     60
ctgttgaaaa gcataggtgc tactctgact gatgtggatg accttatatt caaacttgct    120
tattatgaaa ttcgatatca gttctacaag agagatcagc ttatatggag tgttgttagg    180
cattacagtg aacagttctt gaaacagatg tatgtccttg tattggggtt agatgtactt    240
ggaaacccat ttggattaat tagaggtctg tctgaaggag ttgaagcttt attctatgaa    300
cccttccagg gtgctgttca aggccctgaa gaatttgcag aggggttagt gattggagtg    360
agaagcctct ttggacacac agtaggtggt gcagcaggag ttgtatctcg aatcaccggt    420
tctgttggga aaggtttggc agcaattaca atggacaagg aatatcagca aaaaagaaga    480
gaagagttga gtcgacagcc cagagatttt ggagacagcc tggccagagg aggaaagggc    540
tttctgcgag gagttgttgg tggagtgact ggaataataa caaaacctgt gggaangtgc    600
caaaaaggaa ggagctgctg gattctttaa aggattggaa aaggcttttg gtgctgtgnc    660
cgtccaantg tggaacntaa tatggccata ataccttcca ggcttcaagg cgc           713

<210> 107
<211> 2066
<212> DNA
<213> Homo sapiens

<400> 107
ggcacgaggc ggcggagggc cacaatcaca gctccgggca ttgggggaac ccgagccggc     60
tgcgccgggg gaatccgtgc gggcgccttc cgtcccggtc ccatcctcgc cgcgctccag    120
cacctctgaa gttttgcagc gcccagaaag gaggcgagga aggagggagt gtgtgagagg    180
agggagcaaa aagctcaccc taaaacattt atttcaagga gaaaagaaaa agggggggcg    240
caaaaatggc tggggcaatt atagaaaaca tgagcaccaa gaagctgtgc attgttggtg    300
ggattctgct cgtgttccaa atcatcgcct ttctggtggg aggcttgatt gctccagggc    360
ccacaacggc agtgtcctac atgtcggtga aatgtgtgga tgcccgtaag aaccatcaca    420
agacaaaatg gttcgtgcct tggggaccca atcattgtga caagatccga gacattgaag    480
aggcaattcc aagggaaatt gaagccaatg acatcgtgtt ttctgttcac attcccctcc    540
cccacatgga gatgagtcct tggttccaat tcatgctgtt tatcctgcag ctggacattg    600
ccttcaagct aaacaaccaa atcagagaaa atgcagaagt ctccatggac gtttccctgg    660
cttaccgtga tgacgcattt gctgagtgga ctgaaatggc ccatgaaaga gtaccacgga    720
aactcaaatg caccttcaca tctcccaaga ctccagagca tgagggccgt tactatgaat    780
gtgatgtcct tcctttcatg gaaattgggt ctgtggccca taagttttac cttttaaaca    840
tccggctgcc tgtgaatgag aagaagaaaa tcaatgtggg aattggggag ataaaggata    900
tccggttggt ggggatccac caaaatggag gcttcaccaa ggtgtggttt gccatgaaga    960
ccttccttac gcccagcatc ttcatcatta tggtgtggta ttggaggagg atcaccatga   1020
tgtcccgacc cccagtgctt ctggaaaaag tcatctttgc ccttgggatt tccatgacct   1080
ttatcaatat cccagtggaa tggttttcca tcgggtttga ctggacctgg atgctgctgt   1140
ttggtgacat ccgacagggc atcttctatg cgatgcttct gtccttctgg atcatcttct   1200
gtggcgagca catgatggat cagcacgagc ggaaccacat tgcagggtat tggaagcaag   1260
tcggacccat tgccgttggc tccttctgcc tcttcatatt tgacatgtgt gagagagggg   1320
tacaactcac gaatcccttc tacagtatct ggactacaga cattggaaca gagctggcca   1380
tggccttcat catcgtggct ggaatctgcc tctgcctcta cttcctgttt ctatgcttca   1440
tggtatttca ggtgtttcgg aacatcagtg ggaagcagtc cagcctgcca gctatgagca   1500
aagtccggcg gctacactat gaggggctaa tttttaggtt caagttcctc atgcttatca   1560
ccttggcctg cgctgccatg actgtcatct tcttcatcgt tagtcaggta acggaaggcc   1620
attggaaatg gggcggcgtc acagtccaag tgaacagtgc ctttttcaca ggcatctatg   1680
ggatgtggaa tctgtatgtc tttgctctga tgttcttgta tgcaccatcc cataaaaact   1740
atggagaaga ccagtccaat ggaatgcaac tcccatgtaa atcgagggaa gattgtgctt   1800
tgtttgtttc ggaactttat caagaattgt tcagcgcttc gaaatattcc ttcatcaatg   1860
acaacgcagc ttctggtatt tgagtcaaca aggcaacaca tgtttatcag ctttgcattt   1920
gcagttgtca cagtcacatt gattgtactt gtatacgcac acaaatacac tcatttagcc   1980
tttatctcaa aatgttaaat ataaggaaaa aagcgtcaac aataaatatt cttgagtata   2040
aaaaaaaaaa aaaaaaaaaa aaaaaa                                        2066

<210> 108
<211> 643
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (585)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (594)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (597)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (630)
<223> n equals a,t,g, or c

<400> 108
ggacgaggca tgtatganct gaaaccagaa tgtgccaaac agttcaactt gtatttctat     60
cacttttcaa gggcagaaca gtccaaggca gaagaagcgc aacggaaatt gaaaagacaa    120
aatagagaag atacagcact cccacctccg gtgttgcctc cattctgccc tctgtttgca    180
agcctggtta acattttgca gtcagatgtc atgttgtgca tcatgggaac aattctgcaa    240
tgggctgtgg aacataatgg atatgcctgg tcagagtcca tgctgcaaag ggtgttacat    300
ttaattggca tggcactaca agaagaaaaa caacatttag agaatgtcac ggaagagcat    360
gtagtaacat ttaccttcac tcagaagata tcaaaacctg gtgaagcgcc aaaaaattct    420
cctagcatac tagctatgct ggaaacacta caaaatgctc cctacctaga agtccacaaa    480
gacatgattc ggtggatatt gaagactttt aatgctgtta aaaagatgaa ggagagttca    540
cctaccagtc ccgtggcaga gacagaagga accataatgg aagancataa ttcnganttc    600
aagggacaaa gacaagcttg agaggaagan aaaacataat tgc                      643

<210> 109
<211> 793
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (786)
<223> n equals a,t,g, or c

<400> 109
cagaacctga aatttactgg gtcactccca ttggaaataa gataactgtg gaaacccttt     60
cagataaata caagctaagt agcgaaggta ccttggaaat atctaacata caaattgaag    120
actcaggaag atacacatgt gttgcccaga atgtccaagg ggcagacact cgggtggcaa    180
caattaaggt taacgggacc cttctggatg gtacccaggt gctaaaaata tacgtcaagc    240
agacagaatc ccattccatc ttagtgtcct ggaaagttaa ttccaatgtc atgacgtcaa    300
acttaaaatg gtcgtctgcc accatgaaga ttgataaccc tcacataaca tatactgcca    360
gggtcccagt cgatgtccat gaatacaacc taacgcatct gcagccttcc acagattatg    420
aagtgtgtct cacagtgtcc aatattcatc agcagactca aaagtcatgc gtaaatgtca    480
caaccaaaaa tgccgccttc gcagtggaca tctctgatca agaaaccagt acagcccttg    540
ctgcagtaat ggggtctatg tttgccgtca ttagccttgc gtccattgct gtgtactttg    600
ccaaaagatt taagagaaaa aactaccacc acttcattaa aaaagtatta tggcaaaaaa    660
cctctttcaa tcccactaaa tgagctgtta cccaccactc atttaacctc tggggaaggt    720
ggacagcgag gaaggacaag gtgggttctg gcggacacca ggccaacccg ggtcggacac    780
ttccgnaggt ttt                                                       793

<210> 110
<211> 726
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (218)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (333)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (336)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (371)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (682)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (699)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (712)
<223> n equals a,t,g, or c

<400> 110
aaaaaaatat ggggtcagaa tggttgggtt ttaattgtga ctctgatagt tactgattac     60
ggaaccttgg gcacagtatt taactagtct atatatctgc ttcctcatct gtaaattgga    120
agttattata aagccttcca tatagacttc ttatggaaat aaaatgaaat aattcataca    180
aataccctgg cacatattag gtactcagtg aatgttanct agtattacaa atgtctatga    240
caatttaatt agcatgatgt ctaaaaccgc cattatttga ttagaattag tttagcagga    300
ggatgaaaaa actgagaagg accctaaaat gantanccat gctgttttat ttactccttt    360
ctttatttaa nacatgaaca acactctagg tacagtttta tattttaatg gctatgttct    420
tctcttcgtc cttacatgaa ataccctcac cctctccccc agaaaaaaag aaaagaatca    480
ttccattgtt agaatgcagt ttagagatta taaactccaa actctgtacg tcattaaaat    540
ttatattcac tgggaccttg gaacttagtc ttcaactttt acatgcaata ccattagttt    600
atttaagttc agttggattc actgtttgtc tccctccaca aaccaacctc ttgcatcaga    660
tgttctcctt aacttgctta gngggctgcc atttctttng gatttttttt tnccattttt    720
atcacc                                                               726

<210> 111
<211> 3259
<212> DNA
<213> Homo sapiens

<400> 111
tttgcagtac gggccggatt tcccgggtcg acccacgcgt ccgcggaggc tacgtgaaga     60
gaggcgcggc gtgactgagc tacggttctg gctgcgtcct agaggcatcc ggggcagtaa    120
aaccgctgcg atcgcggagg cggcggccag gccgagaggc aggccgggca ggggtgtcgg    180
acgcagggcg ctgggccggg tttcggcttc ggccacagct ttttttctca aggtgcaatg    240
aaagccttcc acactttctg tgttgtcctt ctggtgtttg ggagtgtctc tgaagccaag    300
tttgatgatt ttgaggatga ggaggacata gtagagtatg atgataatga cttcgctgaa    360
tttgaggatg tcatggaaga ctctgttact gaatctcctc aacgggtcat aatcactgaa    420
gatgatgaag atgagaccac tgtggagttg gaagggcagg atgaaaacca agaaggagat    480
tttgaagatg cagataccca ggagggagat actgagagtg aaccatatga tgatgaagaa    540
tttgaaggtt atgaagacaa accagatact tcttctagca aaaataaaga cccaataacg    600
attgttgatg ttcctgcaca cctccagaac agctgggaga gttattatct agaaattttg    660
atggtgactg gtctgcttgc ttatatcatg aattacatca ttgggaagaa taaaaacagt    720
cgccttgcac aggcctggtt taacactcat agggagcttt tggagagcaa ctttacttta    780
gtgggggatg atggaactaa caaagaagcc acaagcacag gaaagttgaa ccaggagaat    840
gagcacatct ataacctgtg gtgttctggt cgagtgtgct gtgagggcat gcttatccag    900
ctgaggttcc tcaagagaca agacttactg aatgtcctgg cccggatgat gaggccagtg    960
agtgatcaag tgcaaataaa agtaaccatg aatgatgaag acatggatac ctacgtattt   1020
gctgttggca cacggaaagc cttggtgcga ctacagaaag agatgcagga tttgagtgag   1080
ttttgtagtg ataaacctaa gtctggagca aagtatggac tgccggactc tttggccatc   1140
ctgtcagaga tgggagaagt cacagacgga atgatggata caaagatggt tcactttctt   1200
acacactatg ctgacaagat tgaatctgtt catttttcag accagttctc tggtccaaaa   1260
attatgcaag aggaaggtca gcctttaaag ctacctgaca ctaagaggac actgttgttt   1320
acatttaatg tgcctggctc aggtaacact tacccaaagg atatggaggc actgctaccc   1380
ctgatgaaca tggtgattta ttctattgat aaagccaaaa agttccgact caacagagaa   1440
ggcaaacaaa aagcagataa gaaccgtgcc cgagtagaag agaacttctt gaaactgaca   1500
catgtgcaaa gacaggaagc agcacagtct cggcgggagg agaaaaaaag agcagagaag   1560
gagcgaatca tgaatgagga agatcctgag aaacagcgca ggctggagga ggctgcattg   1620
aggcgtgagc aaaagaagtt ggaaaagaag caaatgaaaa tgaaacaaat caaagtgaaa   1680
gcccatgtaa agccatccca gagatttgag ttctgatgcc acctgtaagc tctgaattca   1740
caggaaacat gaaaaacgcc agtccatttc tcaaccttaa atttcagaca gtcttgggca   1800
actgagaaat ccttatttca tcatctactc tgtttggggt ttgggtttta cagagattga   1860
agatacctgg aaagggctct gtttccaaga attttttttt ccagataatc aaattatttt   1920
gattatttta taaaaggaat gatctatgaa atctgtgtag gttttaaata ttttaaaaat   1980
tataatacaa atcatcagtg cttttagtac ttcagtgttt aaagaaatac cgtgaaattt   2040
ataggtagat aaccagattg ttgctttttg tttaaaccaa gcagttgaaa tggctataaa   2100
gactgactct aaaccaagat tctgcaaata atgattggaa ttgcacaata aacattgctt   2160
gatgttttct atttcaggga cccagaacat aatgtagtgt atgtttttag gtgggagatg   2220
ctgataacaa aattaatagg aagtctgtag gcattaggat actgacatgt acatggaaaa   2280
ttctagggac aggagcatca ttttttcctt acctgatacc acgaaccagt gacaacgtga   2340
atgctgtatt ttaagtggtt gtatgtttat tttctggagt aacaaatgca tgaaaaatta   2400
atgcttcacc taggtaagat cattggtctg tgtgaaatca caaatgtttt ttccttcttg   2460
gttgctgcag cctggtggat gttcatggag aagctctgtt ctctatatta tggctgtgtg   2520
ccgttgcttc tccctctgct tttatctttt ccacagttga ggctgggtat gttctttcaa   2580
agaaatggcc atgaatatgt gtaagtatac ttttgaaaat gagctttcct aaactattga   2640
gagttctttc cacctcttgc ggaaccaact cttggaggag aggcccatgt atctgcacga   2700
gcacttagct tgttcagatc tctgcatttt ataaatgctt cttaccaaga aagcattttt   2760
aggtcattgc ttgtaccagg taatttttgc cggggatggg taagggttgg gttttctggt   2820
gggagtgggg tggtgggtat tttttgttga tgctttagtg caggcctgtt ctgaggcaat   2880
aacaagttgc tgtgaaaacg catgtgctgc tgcctttgta actgccatgg aaacttttca   2940
catgggtttt tctccaagtt aatacagaaa tatgtaaact gagagatgca aatgtaatat   3000
ttttaacagt tcatgaagtt gttattaaaa taactaacat aaaacttaat tactttaata   3060
ttatataatt atagtagtgg ccttgtttta caaaccttta aattacattt tagaaatcaa   3120
agttgatagt cttagttatc ttttgagtaa gaaaagcttt cctaaagtcc catacatttg   3180
gaccatggca gctaattttg taacttaagc attcatatga actacctatg gacatctatt   3240
aaagtgattg acaaaaaaa                                                3259

<210> 112
<211> 606
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (583)
<223> n equals a,t,g, or c

<400> 112
tcgacccacg cgtccggttc ggtgcagctg ccagatccgc tgatctagtg cttctcgaaa     60
aaaaccttca ggcggcccat ggatttatag cgcccgtcac aaagggcagg accgctgcaa    120
aaaaatggaa tcttaaaact ttagccatcg ttcgctaaag gaaatgaaag gagaaattca    180
acagtcgctt ggagcctggg ttttgcttac tgtcgatatt caaccrgsat gccttggact    240
ttattgtggg aagaccctat tatttaaaaa tggctcaact gaaatatatg gagaatgtgg    300
ggtatgccca agaggacaga gaacgaatgc acagaaatat tgtcagcctt gcacagaatc    360
tcckgaactt tatgattggs tcyatcttgg atttatggca atgcttcctc tggttttaca    420
ttggttcttc attgaatggt actcggggaa aaagagttcc agcgcacttt tccaacacat    480
cactgcatta tttgaatgca ggcatggcag ctattatcac cttacttgtg agtgatccag    540
ttgggtgttc tttatattcg tttcatgtcg agtattggat gcnttctgga ctgggtacac    600
ggatgg                                                               606

<210> 113
<211> 653
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (330)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (367)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (620)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (633)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (637)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (647)
<223> n equals a,t,g, or c

<400> 113
ttttgctcgt aacaaagaaa ttttaatgca taaggcacag tgagaggctg gaatcattaa     60
gcatcctcaa acacaaaggg cccagcaggc tgagcaaaag aacagagaca ctctccctca    120
ctaccactgg gcgccctgga cagtcccctg aggagtaggg ggcatccagt ytttggcacg    180
gtgcctgggg gaggaagtga ctagcatgat cccagctacc cctctgtggg aatactgcca    240
ccaagaggca gctctttggt ctggataaag tcagtgcaaa tgtccagggg tcaagctctg    300
gaggaatgag ggtggcacag tgccctaggn tgggcagtct ctgaacagtc tcctcagccc    360
tcatggnaaa catgtgggct tcttcttgct ggcagttagg tagaggttgc tgtcatcact    420
gttgaatgcg gacaacattc cccaatgcgt tcgagccccc gatttctcca gcttcagcca    480
gcacattggc ctcaaaggtt cagtgctgcc acacggaaga agaattctcg gacattctca    540
ccatgaagag atgagattgc ccattactca ggctttattt ctggggcacc tggagggggt    600
tttttttcca taaggggctn ttggggaagg ggnttcncaa acttttnggg acc           653

<210> 114
<211> 574
<212> DNA
<213> Homo sapiens

<400> 114
ggggggcgaa ttcccctggc acgaggctga cgcatgcgca tagctaaccg cacccggttc     60
agctcgcctt tcttggccag aggcgccggt tggactcacg ggcggggcat gatggtggtg    120
ggtacgggca cctcgctggc gctctcctcc ctcctgtccc tgctgctctt tgctgggatg    180
cagatgtaca gccgtcagct ggcctccacc gagtggctca ccatccaggg cggcctgctt    240
ggttcgggtc tcttcgtgtt ctcgctcact gccttcaata atctggagaa tcttgtcttt    300
ggcaaaggat tccaagcaaa gatcttccct gagattctcc tgtgcctcct gttggctctc    360
tttgcatctg gcctcatcca ccgagtctgt gtcaccacct gcttcatctt ctccatggtt    420
ggtctgtact acatcaacaa gatctcctcc accctgtacc aggcagcagc tccagtcctc    480
acaccagcca aggtcacagg caagagcaag aagagaaact gaccctgaat gttcaataaa    540
gttgattctt tgtaaaaaaa aaaaaaaaaa aaaa                                574

<210> 115
<211> 1987
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<400> 115
ggcanagccc tgctgaagta caggttcttc tatcagtttc tgttgggcaa tgaacgagca     60
acagcaaagg agatcaggga tgaatatgtg gagacgctga gcaagattta cctgtcttac    120
taccgctctt acctggggcg gctcatgaag gtgcagtatg aggaagtcgc tgagaaagat    180
gatctaatgg gtgtggaaga tacagcaaag aaaggattct tctcaaagcc atcgctccgc    240
agcaggaaca ccattttcac cctaggaacc cgcggctctg tcatctcccc cactgaactt    300
gaggccccca tcctggtgcc tcacacagcg cacgcggaag agcagaggta tccatttgag    360
gccctcttcc gcagccagca ctacgccctc ctagacaatt cctgccgcga ataccttttc    420
atctgtgaat tttttgttgt gtctggccca gctgcacacg acctgttcca tgctgtcatg    480
ggccgtacac tcagcatgac cctgaaacac ctggattctt atctagctga ctgctacgat    540
gccattgctg tttttctctg tatccacatt gttctccggt tccgtaacat tgcagcaaag    600
agggatgttc ctgccctgga caggtactgg gaacaggtgc ttgccttgct atggccacgg    660
tttgaactga tcctggagat gaatgttcag agcgtccgaa gcactgaccc ccagcgccta    720
ggggggttgg atactcggcc ccactatatc acacgccgct atgcagagtt ctcctccgct    780
cttgtcagta tcaaccagac aattcctaat gaacggacca tgcaattgct gggacagctg    840
caggtggagg tggagaattt tgtcctccga gtggcagctg agttctcctc aaggaaggag    900
cagcttgtgt ttctgatcaa caactatgac atgatgctgg gtgtgctgat ggagcgggct    960
gcagatgaca gcaaagaggt tgagagcttc cagcagctgc tcaatgctcg gacacaggaa   1020
ttcattgaag agttgctgtc tccccctttt gggggtttag tggcatttgt gaaggaggct   1080
gaggctttga ttgagcgtgg acaggctgag cgacttcgag gggaagaagc ccgggtaact   1140
cagctgatcc gtggctttgg tagttcctgg aaatcatcag tggaatctct gagtcaggat   1200
gtaatgcgga gtttcaccaa cttcagaaat ggcaccagta tcattcaggg agcgctgacc   1260
cagctgatcc agctctatca tcgcttccac cgggtgctgt cccagccgca gctccgagcc   1320
ctccctgccc gggctgagct catcaacatt caccacctta tggtggagct caagaagcat   1380
aagcccaact tctgatgtgc cagaaaccgc cctgagatct gccggtcatc tccatggact   1440
tctgcacccc attccatacc cttcttcacc tggggtaccc cttccagttt tccccttgct   1500
tcccaggccc ttgacatggc ttacctgcct tcactcccag caccttgccc aacaggataa   1560
gctggatccc cttggccttc tgaatatccc agtgtcttca ggtttcccaa gaccacttcc   1620
ctgtgggctt ccaaaatggc ctttatcatt tctccagtct gtcaccctcc tttcctgctc   1680
ccatacaccc aaggcttgtt tcttcccctg taaaaaccac tgcctcaatc tctggttcac   1740
tcaactagtc accatgtcct gaggcatgaa gcctcctcag ctcttggaat tgctggcaag   1800
gggtgactgc ctctgagtca ttgtgttttt caaagtgatt tcttttctgt agctttttga   1860
cctaagatct cagcaatttg aacactaacc tctcccctcc tggctcaaga attactccga   1920
agtcagtctg cagaaaataa atatttagta tgacatgaca aaaaaaaaaa aaaaaaaaaa   1980
aaaaaac                                                             1987

<210> 116
<211> 634
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<400> 116
cggacgcgtg ggntggccca gctactgttc tcacttctgt gaagaagaaa gtgaagaatg     60
tggggatttt cctaaagaat gaagatgagg aagaagagga ggaggagaaa gatgaggcag    120
aggacctttt gggaagaggt tctcgggcag cattacttac agaaagaaca agaaatgaaa    180
tgactgcaga agagaagcga agagcacatc araaagaact agcggctcaa ctcaatgaag    240
aagcaaagag gcgattract gaacaaaagg gagaacagca gattcaraaa gctcgcaagt    300
ctaatgtgtc ctataaaaac ccatctctga tgcctaagga accgcatatt cgggaaatga    360
agatctacat cgataagaaa tatgagactg taataatgcc cgtgtttggc attgcaacac    420
cgtttcacat tgccacaatc aagaatataa gtatgtccgt ggaaggagat tatacttact    480
tgcgaatcaa cttttattgc caggcagtgc tctgggcagg aatgaaggca acatctttcc    540
taaccctgaa gcgacttttg tcaaggaaat tacataccga gcatcaaata ttaaggcacc    600
cggagaacag acagtaccag ccttgaacct tcag                                634

<210> 117
<211> 1009
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (880)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (929)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (935)
<223> n equals a,t,g, or c

<400> 117
aatttaagag tattaaaaaa acatcattaa taaaaaactg tgattctaaa agccagaagt     60
ataattgttt agtcatggtg ctatctccat gccatgtgaa ggaaataaac ataaaattcg    120
gaccaaattc tggctctaaa gtgcctttag caacagttac agtaattgat caatcagaaa    180
ctaagaagaa ggtttttctg tggaggactg cagcattttg ggsatttaca gtgtttcttg    240
gagatataat tttactcaca gatgttgtta ttcatgagga ccaatggatt ggcgagacag    300
tactacaatc aacatttagc agtcagttat taaatcttgg gagttattca tctattcagc    360
ctgaagaata ttccagtgta gttwgtgaag ttgtacttca agacttactg gcatatgtgt    420
cctcaaaaca ttcctacctc agagatcttc ctccgaggca gcctcagagg gtgaacagta    480
tagactttgt agaattggag caccttcaac ctgatgtatt agtccacgca gtactaagag    540
ttgttgattt cactatactg acagaggcag tatacagtta tagaggacag aagcagaaaa    600
aagttatgtt aacagtggaa caggcccaag atcaacatta tgcgcttgta ttatggggtc    660
ctggagcagc ctggtaccct caacttcaaa ggaaaaaagg ttatatttgg gaatttaaat    720
atctttttgt tcagtgcaat tacacactag aaaacctaga attgcataca acgscttggt    780
catcctgtga gtgcttgttt gatgatgata taagggcaat tacatttaaa gcaaaatttc    840
aaaaaagtgc accctccttt gtgaaggtat cagacttagn aacccaccta gagggtwagt    900
gttcaggagt ggttctgatt aagcccagnt tcagngtggc attccttttc agattcagag    960
ttgcgtaatg gtcacagtct ctgagggttt tttctctttc cacatggta               1009

<210> 118
<211> 715
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (337)
<223> n equals a,t,g, or c

<400> 118
ggctttacca aggatttgat actgtttgcc acctttaatg aagttaaaag tcaaaatctt     60
ttggtaaaag gacttaagct ttctaattcc tatgaagatt ttgagttgaa gaaattacta    120
ttcaaygtaa ttgtgatctt atgtaaagat ttacctactg tacagctatt aattgatggc    180
aaagttattt tggctttgtt tacctatgtt aagaagcctg agaagcaaaa aataattgac    240
tggtctgcag cacagcatga agaattacaa ctgcatgcaa ttgcactttg tcatcagtgg    300
ctcctttatt aatagaagaa tacatgtcat gccaggnaaa tgctcgagtc cttgcatttc    360
tagaatggtg tgagagtgaa gatccgtttt tcagtcatgg taacagtttt catggtacag    420
gtggccgagg caacaagttt gcccagatgc gttacagttt aagactcctg agagccatgg    480
tctaccttga agatgagact gtaaacaaag atctttgtga aaagggaaca attcagcaaa    540
tgataggaat ctttaaaaat ataataagca agcctaatga aaaggaagaa gccattgttt    600
tggaaatcca gtctgatata ttacttatcc tatctggcct ttgtgagaat cacattcaaa    660
ggaaggtatg tatgcctgtg aaagtcttgt tcaggtctcc cagtcaccta acact         715

<210> 119
<211> 2432
<212> DNA
<213> Homo sapiens

<400> 119
atgaagggtc gttggtggga aagatggcgg cgactctggg accccttggg tcgtggcagc     60
agtggcggcg atgtttgtcg gctcgggatg ggtccaggat gttactcctt cttcttttgt    120
tggggtctgg gcaggggcca cagcaagtcg gggcgggtca aacgttcgag tacttgaaac    180
gggagcactc gctgtcgaag ccctaccagg gtgtgggcac aggcagttcc tcactgtgga    240
atctgatggg caatgccatg gtgatgaccc agtatatccg ccttacccca gatatgcaaa    300
gtaaacaggg tgccttgtgg aaccgggtgc catgtttcct gagagactgg gagttgcagg    360
tgcacttcaa aatccatgga caaggaaaga agaatctgca tggggatggc ttggcaatct    420
ggtacacaag gaatcggatg cagccagggc ctgtgtttgg aaacatggac aaatttgtgg    480
ggctgggagt atttgtagac acctacccca atgaggagaa gcagcaagag cgggtattcc    540
cctacatctc agccatggtg aacaacggct ccctcagcta tgatcatgag cgggatgggc    600
ggcctacaga gctgggaggc tgcacagcca ttgtccgcaa tcttcattac gacaccttcc    660
tggtgattcg ctacgtcaag aggcatttga cgataatgat ggatattgat ggcaagcatg    720
agtggaggga ctgcattgaa gtgcccggag tccgcctgcc ccgcggctac tacttcggca    780
cctcctccat cactggggat ctctcagata atcatgatgt catttccttg aagttgtttg    840
aactgacagt ggagagaacc ccagaagagg aaaagctcca tcgagatgtg ttcttgccct    900
cagtggacaa tatgaagctg cctgagatga cagctccact gccgcccctg agtggcctgg    960
ccctcttcct catcgtcttt ttctccctgg tgttttctgt atttgccata gtcattggta   1020
tcatactcta caacaaatgg caggaacaga gccgaaagcg cttctactga gccctcctgc   1080
tgccaccact tttgtgactg tcacccatga ggtatggaag gagcaggcac tggcctgagc   1140
atgcagcctg gagagtgttc ttgtctctag cagctggttg gggactatat tctgtcactg   1200
gagttttgaa tgcagggacc ccgcattccc atggttgtgc atggggacat ctaactctgg   1260
tctgggaagc cacccacccc agggcaatgc tgctgtgatg tgcctttccc tgcagtcctt   1320
ccatgtggga gcagaggtgt gaagagaatt tacgtggttg tgatgccaaa atcacagaac   1380
agaatttcat agcccaggct gccgtgttgt ttgactcaga aggcccttct acttcagttt   1440
tgaatccaca aagaattaaa aactggtaac accacaggct ttctgaccat ccattcgttg   1500
ggttttgcat ttgacccaac cctctgccta cctgaggagc tttctttgga aaccaggatg   1560
gaaacttctt ccctgcctta ccttcctttc actccattca ttgtcctctc tgtgtgcaac   1620
ctgagctggg aaaggcattt ggatgcctct ctgttggggc ctggggctgc agaacacacc   1680
tgcgtttcac tggccttcat taggtggccc tagggagatg gctttctgct ttggatcact   1740
gttccctagc atgggtcttg ggtctattgg catgtccatg gccttcccaa tcaagtctct   1800
tcaggccctc agtgaagttt ggctaaaggt tggtgtaaaa atcaagagaa gcctggaaga   1860
catcatggat gccatggatt agctgtgcaa ctgaccagct ccaggtttga tcaaaccaaa   1920
agcaacattt gtcatgtggt ctgaccatgt ggagatgttt ctggacttgc tagagcctgc   1980
ttagctgcat gttttgtagt tacgattttt ggaatcccac tttgagtgct gaaagtgtaa   2040
ggaagctttc ttcttacacc ttgggcttgg atattgccca gagaagaaat ttggcttttt   2100
ttttcttaat ggacaagaga cagttgctgt tctcatgttc caagtctgag agcaacagac   2160
cctcatcatc tgtgcctgga agagttcact gtcattgagc agcacagcct gagtgctggc   2220
ctctgtcaac ccttattcca ctgccttatt tgacaagggg ttacatgctg ctcaccttac   2280
tgccctggga ttaaatcagt tacaggccag agtctccttg gagggcctgg aactctgagt   2340
cctcctatga acctctgtag cctaaatgaa attcttaaaa tcaccgatgg aaccaaaaaa   2400
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 2432

<210> 120
<211> 776
<212> DNA
<213> Homo sapiens

<400> 120
acctcatggt gtcccacccc cttcggcagc gcagtgtgtc cctggacagc cagatgggct     60
acctcccggc accaggcggc atggccaacc tgcccttcta gaagtcgctg ccagggctgg    120
agccggggca atgttgcaaa tacgataacc ttaacaaagt tcttcccctc aatgttggga    180
tggcctgggt cgtggggtgg ggtggagggg gtgggaaggg gctttttgta agggagtggc    240
atttgtggaa accagatgtg ctggcagctt agggggaagt ggcagtgtgg ggtgggggat    300
tttgcattgg ggttggttcc atttcggcca ccaggactgc ccctccccca ctcctcccaa    360
ttcctatgga gcctctctat tttacctctt tccgtgcatc cctgcacccs ccacaccccc    420
ttcagctatg cttttggagt cctggatggg aatctggggg gagagaggaa ggacaggtca    480
ggtctccccc agccccttct gctcctgtct cctcgtgtcc gcattgctgg agctccacct    540
ccctcttggt ttctccgcac ccgcccattt tccttctgyc tttacctgct tcgtatcctt    600
tccctgctga tgtggctgac ccctctccca cccctccctg caggcggctg gccaggtggg    660
caggtgccag ccggagctgt aaatagamcg ctgcgctttt gtgctggttt gtgcgtgtgc    720
tgtatttctg tgttttgata gaagtcacac aaaaaaaaaa aaaaaggatc cctcga        776

<210> 121
<211> 1788
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<400> 121
ngtagttncg acagaacctc acggctcgcc aaactgaaag tactggattc agtatctggc     60
ctttgcagac aatgtttgct gaccccytac tccagaagag cccagcccag aatacccggc    120
cactccctac aataccagct cctgcttgag aaaggatagg ctttaatttg atggccaatt    180
aggaagaaaa ggcctattta ggtgatgttt taaataaccc aagaaaccca ctgctgagac    240
ttttaatgaa aatcctcact ctcctttcct cgtattttta gttctgtctc ttctctctgc    300
ctttatttgt ccccttggac tcctctcctt attgctaaat ttccaattag gatctggaaa    360
atcctgtccc ttagagattt tcagcagtct ccttgatttt atgtaaaagg tcagcatttc    420
ctgatgggaa ttactaagta gtcttcattc tcttctttcc tttcccatcc cctcacatgg    480
agaagccagg tttccagctg ggtctcctgg aatcgccagg acgcagcttt accaatcttg    540
gctgagggtc aaggtgagat aacgaaatcc taagggaaat ttgtcaaatg tactccccag    600
gtgtgtattt tcctctgggt ataaggtttc ccccaagtgg gcaggagtcc atgtcaggca    660
gtcagatgta tggctatgtc gctgtttgat agcttttaaa atagaactta aaaaaaagaa    720
aaatcagcct caaaggatgg gctggttttt tttttttaaa ccccctttga gctggtttta    780
atgacccagt tgctttgttt gaaagccatt tatttagatg acagatatgt agatataact    840
ggataaataa aaaaagtgaa atcgagattt gaagcagtgg ttaaaatata aactcatagg    900
ggccactccc ttggacagtg tcccccccag cccagacagt acaatggctc agaaattaca    960
catagaaatg acactcctcc ctccaccctc gccaagagct ctgaaccgca agccccacac   1020
aagaaactga atttcagttt ggcaccaagc accccctcgg cccctgcctc ctctccaccc   1080
ttctcctgca ttctaagcga tatttatttt tacattcact cctgtcctgg aatccagccg   1140
ccctgacttc cgcggagaca gcaccagagg ctgctgcacc agaagcttcg gggcgaggcc   1200
cagcacccac tgtgtggccc agctctgggg gccctgcctt gccctgcccc tccctggttc   1260
acctccccca caacagagcg gccgacaccc actgactcca cagatggaaa gaagacaaag   1320
gtacgaggat aacgcgggcg cgctcccttg agtacgtgta agtgcagaat tcaccaggca   1380
cccctgagac cccacggccc caggggtctc catctcacct gtccgttccg cgaacacaca   1440
cctcgatgaa gtccacagtc cccacagaat cctgcgtgtg acatcccccc tctctaatgg   1500
taaatgtttt ggaatgtcca tagataagaa aatggacggc gtggaggaaa gatttcgtgg   1560
ccaggccttt catttcacct ccggatatca gaatactcag actgttcgtc ttcccactcg   1620
ctgcttccgg aaggtccctg agccccaagg cccccgactc tgcctcgggc atgggcgttt   1680
gggtggctct tgctacctcg ctcacccttg gcacctcggc magtctccct actgctgggc   1740
tmtgggaggt gatgtcctgc ttccccgtgg tgggccctgg agagcttg                1788

<210> 122
<211> 416
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (185)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (376)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (403)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (409)
<223> n equals a,t,g, or c

<400> 122
ggcgctccgt catggggatc cagacggtaa gaccctcatt cagtatcctc cactggggga     60
cccctcccca tctggttctg gccactcagc tccggaccag gggctgtcgc tgccgacccc    120
gccccgcagg ctctgggccc accgtggatg ctggggtccc gatcccgcac atccgggctc    180
gggantccgc caggttaccc ctctgccctt ggcatgcctc cgcgctggag ctcgggatcg    240
ccacccctgg gacggtcacc acccaagccc cgggctctta cccagcctgg cggtcacgct    300
gcctcctcta cccacagagc cccgtcctgc tggcctccct gggggtgggg ctggtcaatc    360
tgctcggctg gctgtnggct cctaattggt tcggaagtcc cgncggctna agtcat        416

<210> 123
<211> 370
<212> DNA
<213> Homo sapiens

<400> 123
gattttttct actttaagat cagaactata caagcttctt gctttgtgtc agcatgctgt     60
tgtacccatg ggcaaattct taggtaagac aaaaacacag ccccaagggc aggtagtaat    120
tttttcagaa aaaggtaagg caatcattta tctcagtctg cccaggacag tcccaattta    180
cacatgtata ttctcccaat ctgtaggctg tcttttcatt ttgttgatta tttcatttaa    240
ttttttatta tttatttatt ttatagagac agatctcatt atgttgccca gggtgatcct    300
tgatctcctg gcctcaagtg atcctccaac cttggtctcc caaagtgctg ggattacaga    360
tgtgaactac                                                           370

<210> 124
<211> 705
<212> DNA
<213> Homo sapiens

<400> 124
agcagctcca tgagcacaca gatatcctag aaaatattcc tttctcacac agggcttctg     60
attactcaga aacatgcccc tcttccctga ataaccaaga acatgttcta tgaacccaat    120
ctctgccaca tgtcaatacc tgctcttcaa agcccctttt gaaactcagt tttgtgccaa    180
gtcctctgga tctaattacc ttaaacaagc agatttagcc atttttaaac agacattccc    240
agtcatcctg gtgcttgtac ttctcctaca tgtcatgaag gaccttggat ttactgagaa    300
ctcaagccgt ggccttggct ttgawactta waaggtgtca rcccytgggc cgattgttga    360
tcatcccaga gccctcagtt ctgtacttgt aaaagtggag acagcagttc ctcatcctcc    420
atccttttag cccatggggt ggttgtaagg ctggattgaa atatgcatgt gactaagcca    480
tgtagctata aagtgaggga tgacttgtgt tttggatcac ttattttaat tctacttata    540
atccacggct tagaatattt aaacattgtt tctattaaac tagaaaggtt cagcatttct    600
gtcatttact tctgctatga tacacaagaa cttatgttgg aatgaagtga aaagtaaaat    660
ggccattctt atgaacctaa aaaaaaaaaa aaaaaaaaaa aaatt                    705

<210> 125
<211> 2119
<212> DNA
<213> Homo sapiens

<400> 125
ggcacgagga cgaagggacg ggacccggga gcctggacga gtccgagcgc gtcacctcct     60
cacgctgcgg ctgtcgcccg tgtcccgccg gcccgttccg tgtcgccccg cagtgctgcg    120
gccgccgcgg caccatggct gtgtttgtcg tgctcctggc gttggtggcg ggtgttttgg    180
ggaacgagtt tagtatatta aaatcaccag ggtctgttgt tttccgaaat ggaaattggc    240
ctataccagg agagcggatc ccagacgtgg ctgcattgtc catgggcttc tctgtgaaag    300
aagacctttc ttggccagga ctcgcagtgg gtaacctgtt tcatcgtcct cgggctaccg    360
tcatggtgat ggtgaaggga gtgaacaaac tggctctacc cccaggcagt gtcatttcgt    420
accctttgga gaatgcagtt ccttttagtc ttgacagtgt tgcaaattcc attcactcct    480
tattttctga ggaaactcct gttgttttgc agttggctcc cagtgaggaa agagtgtata    540
tggtagggaa ggcaaactca gtgtttgaag acctttcagt caccttgcgc cagctccgta    600
atcgcctgtt tcaagaaaac tctgttctca gttcactccc cctcaattct ctgagtagga    660
acaatgaagt tgacctgctc tttctttctg aactgcaagt gctacatgat atttcaagct    720
tgctgtctcg tcataagcat ctagccaagg atcattctcc tgatttatat tcactggagc    780
tggcaggttt ggatgaaatt gggaagcgtt atggggaaga ctctgaacaa ttcagagatg    840
cttctaagat ccttgttgac gctctgcaaa agtttgcaga tgacatgtac agtctttatg    900
gtgggaatgc agtggtagag ttagtcactg tcaagtcatt tgacacctcc ctcattagga    960
agacaaggac tatccttgag gcaaaacaag cgaagaaccc agcaagtccc tataaccttg   1020
catataagta taattttgaa tattccgtgg ttttcaacat ggtactttgg ataatgatcg   1080
ccttggcctt ggctgtgatt atcacctctt acaatatttg gaacatggat cctggatatg   1140
atagcatcat ttataggatg acaaaccaga agattcgaat ggattgaatg ttacctgtgc   1200
cagaattaga aaagggggtt ggaaattggc tgttttgtta aaatatatct tttagtgtgc   1260
tttaaagtag atagtatact ttacatttat aaaaaaaaat caaattttgt tctctatgtt   1320
gtgtgtgcct gtgatgtttt tctagagtga attatagtat tgacgtgaat ccccctgtgg   1380
tatagattcc ataatatgct tgaatattat gatatagcca tttaataaca ttgatttcat   1440
tctgtttaat gaatttggaa atatgcactg aaagaaatgt aaaacattta gaatagctcg   1500
tgttatggaa aaaagtgcac tgaatttatt agacaaactt acgaatgctt aacttcttta   1560
cacagcatag gtgaaaatca tatttgggct attgtatact atgaacaatt tgtaaatgtc   1620
ttaatttgat gtaaataact ctgaaacaag agaaaaggtt tttaacttag agtagcccta   1680
aaatatggat gtgcttatat aatcgcttag ttttggaact gtatctgagt aacagaggac   1740
agctgttttt taaccctctt ctgcaagttt gttgacctac atgggctaat atggatacta   1800
aaaatactac attgatctaa gaagaaacta gccttgtgga gtatatagat gcttttcatt   1860
atacacacaa aaatccctga gggacatttt gaggcatgaa tataaaacat ttttatttca   1920
gtaacttttc cccctgtgta agttactatg gtttgtggta caacttcatt ctatagaata   1980
ttaagtggaa gtgggtgaat tctacttttt atgttggagt ggaccaatgt ctatcaagag   2040
tgacaaataa agttaatgat gattccaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2100
aaaaaaaaaa aaaaaaaaa                                                2119

<210> 126
<211> 500
<212> DNA
<213> Homo sapiens

<400> 126
aattcggcag agtgaagcca ccaaaatggt ggtgttcggg tatgaggctg ggactaagcc     60
aagggattca ggtgtggtgc cggtgggaac tgaggaagcg cccaaggttt tcaagatggc    120
agcatctatg catggtcagc ccagtccttc tctagaagat gcaaaactca gaagaccaat    180
ggtcatagaa atcatagaaa aaaattttga ctatcttaga aaagaaatga cacaaaatat    240
atatcaaatg gcgacatttg gaacaacagc tggtttctct ggaatattct caaacttcct    300
gttcagacgc tgcttcaagg ttaaacatga tgctttgaag acatatgcat cattggctac    360
acttccattt ttgtctactg ttgttactga caagcttttt gtaattgatg ctttgtattc    420
agataatata agcaaggaaa actgtgtttt cagaagctca ctgattggca tagtttgtgg    480
tgtttccatc ccagttcttt                                                500

<210> 127
<211> 473
<212> DNA
<213> Homo sapiens

<400> 127
gcacagtgta caaaatttat taatcagtta cttggagttg ttcctttgtc gacaccaaca     60
gaggataagc tggcactgcc tgctgacatc agagctctgc agcaacattt gtgtgtggtg    120
cagctgacga ggttacttgg cttgtaccac accatggata aaaatcagaa attgagtgtg    180
gtcagagaat tgatgttaag gtaccagcat ggactggaat ttgggaaaac ctgtttgaaa    240
acagaattgc aattttctga ctattactgt ctccttgctg tccatgcgct tattgatgta    300
tggagggaaa caggtgatga gaccactgtg tggcaggccc tgactttgct ggaagaggga    360
ttaacccata gcccttccaa tgctcagttc aaattgctgc ttgttcgaat ctactgtatg    420
ctgggtgcat ttgaaccagt ggtggatctt tactccagcc tcgatgctaa gca           473

<210> 128
<211> 772
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (737)
<223> n equals a,t,g, or c

<400> 128
ggaaaatttc agaccacagg ttggttattg ggtgacagct acttattttt aaaaccatct     60
agattgttat aactgtgtgt agatgacaat tgccctagaa atgttgtatg cttttgaaaa    120
gcttacataa ttgctcatat ggcaattgca aaatcatccc ttgacgcgaa tttacaccag    180
agaagaaagt gtcttactta aaatttcagt ctttccctcc tgcagagagg aggcggccgg    240
gtagtgggga agggagggct agtaaggaag ataggaagag gggaggagtt tgtgcaatga    300
gcagaaaaaa gtcactgaag agtttataaa cagtctctgt actgaggaga tgacatttga    360
aactgtggga aaaaaaacca taaacccaat catttgtcct gcttttatgg gggrgatgat    420
tatccatttg gcttttgtcc ttttatgttt taaagattgt caaaataaaa acaacgtatt    480
catagcattt tatttcctaa tttgtcagtt gaaaactacc caaaaaaaca ctacagaaga    540
gtttattcag aatctctatt acctgtcatt tcagaatttt tttctcctta attttaaaag    600
agcagtgaag gtttcagtga gaaattttcc accagaaacc agtttaggaa gtctgttatt    660
tggaggatgc ttggtggtct gtaatcttaa aatctgagac ggtwaaaggr tttttcmaaa    720
twatcgaaag ccggggnttg taggggaggt aatgrtgtta csgtataggg ga            772

<210> 129
<211> 1451
<212> DNA
<213> Homo sapiens

<400> 129
ctccattgct tcatggatac tggtcctatc atgctctttg aggctattga actcatcaat     60
acagcaaagg cccgcatctg caagaactaa tgccccagcc tccaaattcc attctcctga    120
gtcttttaca gcagttaccg tcagactttg ttctccgcct ttgtcctaat ccacaccagc    180
aggtggagcc gcagttaaag tttccgagtc cattccggga gcgggagccc atcttgctgg    240
ctgccgaggc cctcgctgga ggaggagggt cagaactcgg gtgcagccaa tcgagggcaa    300
cgctgctact tatcagagca gaatgggctg tagtttagtg aaataggaaa gctgcaamac    360
actgtggagt gctcccgtgt aaataaaaag aggaaaaaag tttctcaagt cgccgctgca    420
cgacgtctgg ccggcgctgg agcgggggtc tgcgctctcc cgagcggccg cgcgctggac    480
tttattgtgc cgcaaccagc cccagttccc attgtttgtg tttttttcaa aatatggcaa    540
aggttcaggt gaacaatgta gtggtgctgg ataacccttc tcctttctac aacccgttcc    600
agttcgagat caccttcgag tgcatcgagg acctgtctga agacttggaa tggaaaatta    660
tctatgtggg ctctgcagaa agtgaagaat acgatcaagt tttagactct gttttagtgg    720
gtcctgttcc cgcaggaagg catatgtttg tatttcaggc tgatgcacct aatccaggac    780
tcattccaga tgcagatgca gtaggcgtaa ctgttgtgct aattacttgt acctatcgag    840
gacaagaatt tattagagtt ggctattatg taaataatga atatactgag acagaattaa    900
gggaaaatcc accagtaaaa ccagactttt ctaagcttca aaggaatatt ttggcatcta    960
atcccagggt cacaagattc cacattaatt gggaagataa cacagaaaaa ctggaagatg   1020
cagagagcag taatccaaat ctacagtcac ttctttcaac agatgcatta ccttcagcat   1080
caaagggatg gtccacatca gaaaactcac taaatgtcat gttagaatcc cacatggact   1140
gcatgtgacc acctaccatc cctttagtac aaattaagct attaaaaata cacagaacta   1200
tttccctgaa attccgtaag tacatagtca aaacacaatg tgaagaattt gtttaaaaac   1260
atcctgtaga aagtttataa gaaaaccagt atttgaacaa attgtggaat ataaatacaa   1320
ctatttttaa gtaatttttt tctctaatgt gttattttat ttgttctgaa actaatctga   1380
ttaaagcata tatattattt tcttctcctt tatatgtaat gaaagcactt ataaagaaac   1440
aggaatcatt a                                                        1451

<210> 130
<211> 648
<212> DNA
<213> Homo sapiens

<400> 130
ttctgttggg attttttatt tggtgtgcgt gaatgaggag cttcgccctg cttgaatggg     60
acccctctca gtggtgtcag cttggggagg aggagatggc cctggagact aaatacttgt    120
atgctttctt accctcttag gtctcagcct tagatccaag gacagtccaa ggaagtccta    180
agaccatgga gttggtgatc tgggatctgg gtttgctgat atttctcacc gtggtgagtt    240
gatgccaaga gccagaaccc acarccagag gctcagctgg tccgtgttta tgcagatggg    300
aacctcaaat cactggtctc acttgtcctt tgtttcagaa tctcttggtg gtgtttgtgg    360
gcacgagagg ggcagagaat ggagagtgag gctaccacat gaagcgtcac cagagctgct    420
ccctgctgcc tgctcagagc accccggatc cactgttcaa tctgcacaag attcsgggtc    480
cagacatggg agacttcagc tgcctcagag gaccgtkgac agggaargcc agcctcgcat    540
ccctctgtcc atgcctggaa tgactttaat amccaagagt tttatttttg aatttgtagc    600
tgtcgttcac tttttaccca cccattcaat aaaccttaca gaattgca                 648

<210> 131
<211> 525
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (470)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (501)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (525)
<223> n equals a,t,g, or c

<400> 131
ttaacagaag cactctgcct ggaggtgcga ccaacatatt ttgagatgaa gaacgaaaaa     60
ctgctgtcca aagcatcaga accaaaatac cagctttttg ttccccagct tgtgactggc    120
agatgcgcta caagagcttt tcatagaaaa tcacatagtt tggatctgaa catcagtgag    180
aaactgactt tattacccac tttatatgaa atacatagta agactactgc ctattccaga    240
ctaaatgaaa cacagcctat tgacctttca ggcttgcttt acaatctagt aaaaatagct    300
attcctttca gaatccatcc agttttgatc ctagtatgct gctgcaaaga ttttcagtgg    360
ccccccatga gacccagaca caaagaggag gagaatttca gtgtggtcta gaagctgctt    420
catgtattct gaccatacta atactaacaa tctggacttt ccgatggacn ggccctcagc    480
ggcaggagca tgccggaggt ncagaccagg aagagcactc tcccn                    525

<210> 132
<211> 1437
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (66)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (82)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (780)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1436)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1437)
<223> n equals a,t,g, or c

<400> 132
aactggtggg tcccccgggn ctggcaggaa ttcggcacgg gctctaattg ctagttgtaa     60
aactgntatc caaattttca gnaaaagaca gcttcagctt gcaaattcta tcctctaaac    120
ttatctggtg cattctcccc accccacccc cattatataa gggctatttt agatgctttt    180
aacctcccca acaaataatt tgccaagtgt ccaatgagaa cttatcatgt tggtgtgtta    240
ggtaaatcgg gcaaatatga tagtgtctta cattgggcct tgattttaag ttgttatatt    300
tgtacaatcg agtattttag aaattacatg aaacatgaaa cagtttttgc aatttttttt    360
aaactgggca tctggtttct aaaaatttat ttgaaacaat ctagaatttt cttggtgcaa    420
agtgtatcat gtggratatc cycatatttt taccatattt taagaacttt aagacgatta    480
attgtaaata atttatttga ttggtgcagt ycyaatccct aaatcataat cttaaaatca    540
ggaatgtgtg gagaacagag ccatgtcata tcactttgct cttaccattc cttttgatca    600
gcctcaattc agcctcattg tgtagtatgt tttttctttc tatgaaaaac aacagaaagc    660
atttcattta tttgcctatg ttcaaatatg tttaataatg accaaagtgc attctgagtt    720
ttttcaagga akgtaatact ggagctttaa gaacatacyt agttycycak gkgaaaactn    780
aggctttgtc tgatgttttt ccttcctcta ttgtctaatg ttgaggttgt ttttaggaat    840
tatgttttat aaactttttc aatataaggt acatgcctat acagaactta acattttgca    900
cagaatatat caaatatatt ttgagaaaaa aagtacggca tgagttctgt taggaataaa    960
agatgaaact attgtatctc acaaaaaatc ttatttcaga atggaaatat ttttgagaaa   1020
agtagctgag tatactggtt taagaaaatg cttgttttag attgaggtta acttagagtt   1080
gggagttgat ttattaagta cagtatacct ctcaacagtt tataaataat atgttgaatt   1140
atgtcagtgt gggcagcagt agaatactaa aaggaaaatg tcatgttaag caatttcaga   1200
acattaactg aactattttc aaagcagaaa aattgacatt gctgccttta agaataccat   1260
gaatgtaaga aattgaaaga aattgtaaaa tatcacataa tatagaaatg gcagttcaaa   1320
gagaattgtg gcagatgttg tgtgtgaact gttgtttctt tgccacatgt gttgtatttg   1380
aaagttttac agtaagttta aaataaaaca ttctgtgact gaaaaaaaaa aaaaann      1437

<210> 133
<211> 466
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (361)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (395)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (459)
<223> n equals a,t,g, or c

<400> 133
cggcgctgcc ggggtgaaat cgtaggacag tgaagatgct gctggaattg tccgaggagc     60
ataaggaaca cctggccttc ctgcctcaag tggacagcgc gggtcagcgg gcgtgggggc    120
ggtgttctgt gggctgggga ggaggtcaaa ggcagcgcct ggcactcaac agccttctga    180
ctttcattgc agtggtcgcc gagtttgggc ggattgctgt ggaattcctg agacgsggcg    240
caaacccaaa aatctacgra ggcgccgcca gtaagaaggg aaaggggaag gctccgcagg    300
cttctagggc ggttgcgagc cattccctgt ctcccgggag agaaacggat tattgcgagt    360
nctagggtct tgttccgatt gtagtagaat aaaancagca gagtctttca gtcagggtgc    420
aatcctgccc gtcccttaag tagtgtgaga ttgttaaanc tctatt                   466

<210> 134
<211> 572
<212> DNA
<213> Homo sapiens

<400> 134
cgaccgtacg gcaaatgaag atagatttga agatgatcga tattttttgg gtttcttgtc     60
caactcaaaa agatttaatg ttgcaatcac cagacccaaa gctttgctga tagtgctggr    120
aaacccccat gttctcgttc gagacccctg ttttggtgct ttgctggaat acagtattac    180
aaacggtgtt tacatgggat gcgatttacc tcctgcactg cagtctctgc aaaactgtgg    240
cgagggggtg gcagacccct cctacccrgt ggtgccagaa tccacaggac cagagaagca    300
tcaggagccc agctgatctg cagtggctga cagcagggag gccatgtgct cagcctggcc    360
acgttgccgt tacagtctgc tccgtggctc ctgtggcctg cccttgtctc gcagccaggc    420
agggtcgtgt gtgggtgtgg ggctgccagg ttggacgcag ctgctgctgc cctgactttg    480
gcatatgcca gcctgtwcct gccacagggc agtcactgcc gcctaccctg aaataaaccc    540
tcgagtgacc cccaaaaaaa aaaaaaaaaa aa                                  572

<210> 135
<211> 1076
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (35)
<223> n equals a,t,g, or c

<400> 135
gacggctgca gaacatccgc cgcaccgctg ggggncaacg ttgtcggacc gaggagtccg     60
aggtggcgac tgagtgagat acccagctgt gcggagctag gacgcggaac atcccagagg    120
ccagcatcaa catgctgcca cctgcccacc accaggcctt tgtccgacat cgcctggagg    180
aggccttccg tgtggccctt gttgggcacc gacatcccct gcctgtcctg gcctatgtcc    240
gcctcacaca ccggagatct gggaggttcc tgtcccagga tgaccttgtg cagtccattg    300
gtgtgagtgc agcactaggg gcagccggcg tggtgctctg gggggacctg agcctctcca    360
gctctgagga ggagtgctgg catctccatg actacctggt ggacaccttg ggcccctatg    420
tgatcaatgt gaccagggca gcgatggcct gcagtcacca gcggtgccat ggccacgggc    480
gctgtgcccg gcgagatcca ggacagatgg aagcctttct acacctgtgg ccagacggca    540
gccttggaga ttggaagtcc ttcagctgcc actgttactg gggctgggct ggccccacct    600
gccaggagcc caggcctggg cctaaagaag cagtataaag ccagggcccc tgccactgcc    660
tcttcttttc cctgctgcca cttttccagt cctggaacta ctctgtccca ctcttgctct    720
attcagttta cagtcaaccc tcccaagcac acaccccgct tcccttggaa tccctgaggg    780
gtagaagggg ccagaaaaaa cgcttataaa accagaggcc ctctgagatc atgtgagtcc    840
tccatggcaa ggaagcagtt ccagggagag tcaggttcca gctagttagg gctgccagcc    900
tagggctttg tgcctacacc tcactaagcc catggagagg tcacagatgg gccgtgcacg    960
ggcagatggg ccccaaaaaa tcttggcgaa ggtcggtaaa gtgctaagct gttgtctgca   1020
ctctttcatc ataaagtcac ttttttccac taaaaaaaaa aaaaaaaaaa ctcgag       1076

<210> 136
<211> 713
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (712)
<223> n equals a,t,g, or c

<400> 136
agaaaacaga ttcctatttt aaccccaaaa tgaaactaaa tcggcagcta atattctgta     60
cattggctgc tttggctgag gaacgaaaac ctttggaatg tctagatgct tttggagcca    120
ctgggataat gggattacag tgggcaaaac atcttggaaa tgcagtcaaa gttacaatca    180
atgacttgaa tgaaaattct gtgacactga ttcaggaaaa ctgccattta aacaaattga    240
aagtggtggt ggacagtaag gaaaaggaaa agagtgatga tattcttgaa gaaggagaga    300
aaaatcttgg taatattaag gtgaccaaaa tggatgccaa tgtactgatg catttgagat    360
cttttgattt catacatcta gacccttttg gaacatcagt gaattatcta gattctgcat    420
tcagaaatat aagaaacctt ggcatagtgt cagtgacttc tacagatatc agttctttat    480
atgccaaggc acagcatgtt gcccggcgtc actacggatg taacattgtc cgaactgaat    540
attacaagga actagcagcc agaattgttg tagctgcagt ggcaagagct gcagcccgat    600
gcaacaaagg catagaagta ctgtttgcag tggctctgga acattttgtg ttggtagttg    660
tgagagtttg aggggaccta cttcagcaga tgaaacagcc aagaagattc ant           713

<210> 137
<211> 780
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (557)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (596)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (624)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (705)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (722)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (732)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (767)
<223> n equals a,t,g, or c

<400> 137
gcttattgcc cgcgcggtga gggagcgtgg tctcgcgcaa scggcgtgcg gtcccgcggc     60
gctgcagttg tgtccagccg gtcacggggc ggctatggcg gccacgttct tcggagaggt    120
ggtgaaggcg ccgtgccgag ctgggactga ggacgaagag gaggaggagg aggggcggag    180
ggagacgccc gaggacaggg aggtgcgtct gcagctggcg cggaagaggg aagtgcggct    240
ccttcgaaga caaacaaaaa catctttgga agtttctttg ctagaaaaat atccgtgctc    300
caagtttata attgctatag gaaataatgc agtagcattt ctgtcatcat ttgttatgaa    360
ttcaggagtc tgggaggaag ttggttgtgc taaactctgg aatgaatggt gtagaacaac    420
agacactaca catctgtcct ccacagaggc tttttgtgtg ttttatcatc taaaatccaa    480
tccctcggtt tttctctgtc agtgcagttg ctatgttgca gaagatcaac agtatcagtg    540
gctggaaaag gtttttnggc tcttgtccaa ggaagaacat gcagataact attctncaca    600
tgtcgacatg tttaccggat tatnaaaacc tcagaatcca ccggggcagc ctttcctttc    660
tccttttccc tggagaaggc ccttaaaacm cagaattcca aagantcggg cgtggtttgg    720
tnccattggc tnaggaacaa ccggattata gttacacgga ccttccnggg caggcagttc    780

<210> 138
<211> 629
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (372)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (374)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (494)
<223> n equals a,t,g, or c

<400> 138
agctgatgcg gctggaccgg ycggggaaac agtattttct ggaagggggc ccctctsaas     60
cggtccagga tcctgcacat ggcgctgacc ggggcctcag acccctctgc agaggcagag    120
gccaacgggg agaagccctt tctgctgcgg gcattgcaga tcgcgctggt ggtctccctc    180
tactgggtca cctccatctc catggtgttc cttaataagt acctgctgga cagcccctcc    240
ctgcggctgg acacccccat cttcgtcacc ttctaccagt gcctggtgac cacgctgctg    300
tgcaaaggcc tcagcgctct ggccgcctgc tgccctggtg ccgtggactt ccccagcttg    360
cgcctggacc tnanggtggc ccgcagcgtc ctgcccctgt cggtggtctt catcggcatg    420
atcaccttca ataacctctg ctyaagtacg tcggtgtggc cttctacaat gtgggccgct    480
cactcaccac cgtnttcaac gtgctgctct cctacctgct gctcaagsaa mccacctcct    540
tctatgccct gcttcacctg cggtattcat catcgggggc ttctggcttg gtgtgggacc    600
aggagggggc agaaggcacc ttgtcgtgg                                      629

<210> 139
<211> 411
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (411)
<223> n equals a,t,g, or c

<400> 139
cccacgcgtc cggcggtggt ctcattcctg gaaaatctct tgtgtttgca actatggagc     60
tgctgatgtt cattttagta cggcatatgc cacatctcag taccaaggtg tcagactctc    120
caagtcacat agccactaaa actcgactat cagaasaaag tgctcgtttg gtggcagcca    180
cagttaccat actctctgat ttaccatccc tttgttcacc cgctggatgt atgacaatcc    240
tgcccacaat tctgttctta attgcmagaa tattgaaaga cacagcaata aagtctgcag    300
ataatcaggt tcctccacca gtcagtgcag ctcttcaagg gattaaaagt attgtgacac    360
tttcaatggc caaaactgag gctggcgttc aaaaacagtg gacagctctg n             411

<210> 140
<211> 957
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (934)
<223> n equals a,t,g, or c

<400> 140
aaggtcatgc aaaatttagg ncgtgtatta aaagcctggg tagtgtctca tcctgatctt     60
gtgtattggc aaggtcttga ctcactttgt gctccattcc tatatctaaa cttcaataat    120
gaagccttgg cttatgcatg tatgtctgct tttattccca aatacctgta taacttcttc    180
ttaaaagaca actcacatgt aatacaagag tatctgactg tcttctctca gatgattgca    240
tttcatgatc cagagctgag taatcatctc aatgagattg gtttcattcc agatctctat    300
gccatccctt ggtttcttac catgtttact catgtatttc cactacacaa aattttccac    360
ctctgggata ccttactact tgggaattcc tctttcccat tctgtattgg agtagcaatt    420
cttcagcagc tgcgggaccg gcttttggct aatggcttta akgagtgtat tcttctcttc    480
tccgatttac cagaaattga cattgaacgc tgtgtgagag aatctatcaa cctgttttgt    540
tggactccta aaagtgctac ttacagacag catgctcaac ctccaaagcc atcttctgac    600
agcagtggag gcagaagttc ggcaccttat ttctctgctg agtgtccaga tcctccaaag    660
acagatctgt caagagaatc catcccatta aatgacctga agtcagaagt atcaccacgg    720
atttcagcag aggacctgat tgacttgtgt gagctcacag tgacaggcca cttcaaaaca    780
cccagcaaga aaacaaagtc cagtaaacca aagctcctgg tggtttgaca tccggawtag    840
tgaagacttt attcgtggtc acatttcagg aaggcattca acattccatc agtgctgcct    900
tcaytgcaga aggggggagc tttacccagg gggnccttta cactgggcta atgggct       957

<210> 141
<211> 895
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (430)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (825)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (853)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (875)
<223> n equals a,t,g, or c

<400> 141
gtcgattcac caatgcctcc ccagtaactg gactggaact tgtaccatag gctatgtaac     60
cccagacatc ttcatagccc ctggcaatct ctctcttcca ataccaatct atgggaattc    120
cccgttgccc agggtgagga gggcaatcca tttcattccc cttctcgcgg gactcggcat    180
tctagctggt acgggaaccg gaattgctgg aatcacaaaa gcttccctca cctatagcca    240
gctctcaaag gaaatagcca acaacattga caccatggct aaagccttaa cgaccatgca    300
agaacaaatc gactctttag cagccgtagt ccttcaaaat cgtcgaggac tagacatgtt    360
aacggcagca cagggaggaa tttgtttggc cttagatgaa aaatgttgct tttgggtaaa    420
tcaatcaggn aamgtacaag acaacatcag acaactccta aatcaagcct ccagtttacg    480
ggaacgagcc aytcagggtk ggttaaawtg ggraggract tggaaatggk tctcttgggt    540
tcttcccctt amaggcccac ttgttagtct cctacttttg ctcctttttg gtccatgtct    600
cctaaatcta ataacccaat ttgtctcctc tcgccttcag gccataaagc tccagacgaa    660
tctcagtgca ggacgccatc ctcgcaatat tcaagagtca cccttctaag gaggacccct    720
agactgctcg stagtgggaa cagacagagg cgaaatcctg ccccgtyttc ccgtgggacc    780
kggstggata tggtttwwgr ccaatccaca gagccatcct ggccntgtac agctaggcaa    840
gagggccaag ganccacagg aacaaccatt acagnccctt ttgttcaggc aggga         895

<210> 142
<211> 779
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (728)
<223> n equals a,t,g, or c

<400> 142
gtgaagggtt atactctgct gtcggagggc attgatgaga tggtgggcat catctacaag     60
cccaaaacta aagagactcg ggagacctat gaggtgctac tcagcttcat ccaggctgct    120
cttggggacc agccacgtga tatcctttgt ggggcagctg atgaagttct agctgttcta    180
aagaatgaaa agctgcggga caaggaaagg cgaaaggaga ttgacctgct gctgggtcaa    240
acagatgata ccagatacca tgtgctagtg aacctgggca aaaagatcac agactatggt    300
ggagataagg aaatccaaaa tatgggtaag tgcgcgcttt atgttctgat catgttcatt    360
ggttgttgtt gacccctaaa catgcatctt ctagcatcat tcatttaaaa ccttaatgtc    420
agtgagttcc cataatctgt tctgtgtttt ttgaagagtt acaattgatg gacaccagaa    480
tccctagatt ccagcagctg ttccttactc tgagaccctt ttattgtgtg gaatatgara    540
aaatgtgggc agagccttgg gggctcaagt ggttgagcaa gcaragctgg gctgactcca    600
aggctggcag gtggagaagg tcttggcagg agcagcatag gtggctctct tcatgttgat    660
catctaagta tctgtatgtg tccttaggca cttaggatct tttcctgagg agaggtagtc    720
ggggaggnca ttggctccag agtgccttgt tttactaggc ctttcactgc cctcttttt     779

<210> 143
<211> 1575
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1524)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1556)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1571)
<223> n equals a,t,g, or c

<400> 143
agctgtgggg agcagagcgn ctttgggsam gagtggagtg actagacacc taatgccctg     60
gcagctggag actcaaactc ctgtacagct accttctggg aaatagtttt tracacctat    120
ttttcagatt cttgtccgga atttctgctg ctcttttcaa aaaagggcat taacaattct    180
ctggaaataa agcacctgtt agcctgacat atgcaaaaag cagggcggca tcacccatta    240
cgagctcccc cagccagcag tcagtattgg attggccttg cctggctggt ggcagtttgg    300
gagaaacagc caaagaggtt agtttatttc aacaccaaat tagaccatgg cccatttcca    360
acgggtctct ttaaaggcct ctatggaata cattgcctgg tttccttctt tgcagttcac    420
cacagcaagg aatgtcacct ccatcccaag ccaccatttt ctcatgaagg caaatccaag    480
aagggcttgc agttcttgct gaagggggta ccatttgtgg gcagagtgat caataccatc    540
tagttggggg aggaggagct tatttcttgg tgtacttgaa tcagaaggtc cctgcaagcc    600
agtatgcttc atttgccagt ggccagaaat tctcccttgc ctccttgatt gaggtgtccc    660
agatgtagta ttcccacagg ggtctggcag gcccctcctg taaccactcc agtcacattt    720
tctgctcttg aggcagaggt gacatcagga cgtttacagc ctccacatga attgagtgtt    780
catttacctc agtattaccg tgttcatttt tgtcctcgtg ctacagttag ctccctgccg    840
cctcttgcag gtcttacttc agctcttgcc tgtgacccac acagcttctg ggctctgcct    900
ctgctctaag aagtgctgtg ggggtagaga accaggaagg acatgctgtt gggaatgtac    960
acctgggcag aggtggccct gttaagatgt gactgtagcc acagccaggg atgggatccc   1020
tgggtctctg gaatctgaaa cctcaacaaa taccagtctt gacccctagc agcagagata   1080
agaataaagg ggttggtttg ctattaagtc agatgggggc tctctccttg tcatgctgtc   1140
cctgtgggta acagacaggg attgaccatc ttactgttgt acaggtagct ggtggtgttg   1200
gattatccca ttgaagctgg gacagctgtt cctttctcat agtgataact tgggtctgtt   1260
gtcctctaag gaacgtgaaa catacacttc ttaagctgaa ccacgtaaac ttgaaattct   1320
gcgcactggg agaaatgtgt cctgtgtttc aaaggataaa actgttctaa aggcttccag   1380
ggtcatgatg ggatttttta aataaatgca aaaaataaaa ataaaaaaga aaaaagaaaa   1440
caaaaaaaaa aargaaaaaa tgctaggttg gggaggcgct gttctggatc cccaccgggc   1500
tgggaaccaa gaatgtcgtt tccnttttta aagaagtttt aaacgccccg gggggnggat   1560
atttataacc naaat                                                    1575

<210> 144
<211> 722
<212> DNA
<213> Homo sapiens

<400> 144
tgcgtcgtag cggccgccct tttttttttt tttttttttt tttttttttt tttttttttt     60
tttttttttt tttccaaatc ttgactttat ttttaatata aaaaatgcaa atttggaaac    120
ccaccctact ttccccaaca taatgcttta cctcttaaaa ataaaaataa agtactaatt    180
ctatatacat cacaggtacc atacaaaaat gtatccaaag tttctattgc taccaaagtg    240
ttctaaatta aaacaagtta cagaaagccc ctcattgtaa acaaaagatt acaagttata    300
aaatcaaagt acacacaggc cagagtcatt tatacaatgc aatgcattct gctcccaggc    360
caagttgaat ttttatgtgc ctgtataaaa atgcatatca atataccttt gcaaatggta    420
tttttcatta taaagcaaat gaatacactt tctacaataa ataatccgct gggaggcaca    480
ctgcggggtt tgaggtgggc gggacgacgg gagcggggac acacccaccg gcggtcacgg    540
gcagcggagt gtttttggtg atctgccaag tgatgtacmc agcataactt tattctcccc    600
tctttccaca aagtaccatt cmaaataatg tcattttctt tcttaaaata cacatttgtc    660
attgtaaatt tacatcccgt cttattaaat aagtggtact ctgcggacgc gtgggtcgac    720
cc                                                                   722

<210> 145
<211> 850
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (781)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (802)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (821)
<223> n equals a,t,g, or c

<400> 145
ttgtagccct tgtacggtcc ggaattcccg ggtcgaccca cgcgtccgcc cacgcgtccg     60
cccacgmgtc cggtcgattg gctcttagag catattttta atacaaaatc tgtctttgtg    120
aatagagaat agggacgtat tttttaaaat tgctaccaat cccaaggagc aaggagcatc    180
gatgctttga cttttctgca gggcaggtga cttggcctag ctggttttgg gtggtgagtg    240
cagtgagtgg gccatgacac agtacacgcc atgttcacct gtttcccaaa atgtttaggt    300
ttttccccty cagtaaatgt gactgtctct ccccgttctg aagaaagcca tacaacgacg    360
gtttctggtg gcaatgggag cgtgttccag gcgggcccgc agcttcaggc actggctaac    420
ttagaagcca rgagggggtc tataggtgct gctctctcat cccgggatgt cagtgggctg    480
cctgtttatg ctcagtcagg agagcctagg aggctgaccc aggcacaggt ggcagcgttt    540
cctggagaga atgctttgga acactcttca gaccaggaca cctgggacag cctgaggagc    600
ccgggtttct gcagcccttt gtcatctggt ggtggagcag agtccctgcc gcctgggggg    660
cctggacatg cagaggcagg acacctcggc aaggtttgtg acttccacct gaaccaccag    720
cagcccagcc ccaccagcgt cctgcctaac agaggtgggc agcccctccg ctttgagaaa    780
nttttgttct gttggattag cntggcattg ggattgttgc ntacagggat tgttgcccca    840
agccaggggc                                                           850

<210> 146
<211> 481
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<400> 146
tttcaggctc cagggagcag tgtcagggcc agggagacga tggtctccgt gactatggcc     60
acttccgagt ggatccagtt ctttaaggaa gccggcattc ctccaggacc tgccgtcaat    120
tatgccgtga tgtttgtgga taataggatt cagaagagca tgctgctgga tctcaataag    180
gagataatga atgagctggg cgtgaccgtg gtgggtgaca tcatcgccat tctcaagcat    240
gccaaagtgg tgcaccgtca ggacatgtgc aaagctgcca ctgagtcagt accctgcagc    300
cctagccccc ttgcaggcga aattcgccgt ggcaccagtg ctgcctcccg aatgatcacc    360
aacagcctga accatgactc tccacccagc acacccccca ggcgcccgga caccagcacc    420
tccaagatct ccggtcactg tgtccaacaa gatagcagca aagantgcca aggccactgc    480
a                                                                    481

<210> 147
<211> 830
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (691)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (724)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (729)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (740)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (756)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (809)
<223> n equals a,t,g, or c

<400> 147
gggaggagga ggaggacggg gaggagcttc gccgcggcct gctccgccca gccggggtcg     60
gtggccgcat ggcttcggtc tcctctgcga ccttctcggg ccacggggct cggtccctac    120
tgcagttcct gcggctggta gggcagctca agagagtccc acgaactggc tgggtataca    180
gaaatgtcca gaggccggag agcgtttcag atcacatgta ccggatggca gttatggcta    240
tggtgatcaa agatgaccgt cttaacaaag accggaagct atgaagcaga taacccagct    300
cctaccagag gacctcagaa aggagctcta tgaactttgg gaagagtacg agacccaatc    360
tagtgcagaa gccaaatttg tgaagcagct agaccaatgt gaaatgattc ttcaagcatc    420
tgaatatgaa gaccttgaac acaaacctgg gagactgcaa gacttctatg attccacagc    480
aggaaaattc aatcaccctg agatagtcca gcttgtttct gaacttgagg cagaaagaag    540
cactaacata gctgcagtgc cagtgagcca cactcctgag acactctcta aattgctgca    600
ctcctgtaac aaacattatt tttccatttc attgtattgt gttttgccat tgttggtctg    660
ttgatttcct agatgtgagc tgtttgtttc nattggctga acttcagcaa gaatgtggtc    720
cacnttggnc taaagaagcn cagaccagga accggnctga agtgcatggt gacactggag    780
gggcatccct gttatgacta ataataatnt tacccctaaa aaaaaaaagt               830

<210> 148
<211> 469
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (329)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (442)
<223> n equals a,t,g, or c

<400> 148
ggccccggga tgctacacac aacccagctg taccagcatg tgccagagac acgctggcca     60
atcgtgtact cgccgcgcta caacatcacc ttcatgggcc tggagaagct gcatcccttt    120
gatgccggaa aatggggcaa agtgatcaat ttcctaaaag aagagaagct tctgtctgac    180
agcatgctgg tggaggcgcg ggaggcctcg gaggaggacc tgctggtggt gcacacgarg    240
cgctatctta atgagctcaa gtggtccttt gctgttgcta ccatcacaga aatccccccc    300
gttatcttcc tccccaactt ccttgtgcna ragraagtgc tgaggccctt csgamccara    360
caggargaac cataatggcg gggaarctgg ctktggarcr aggytgggca tcaacktggg    420
ggtggsttcc acactgtcca anaacgtggg ggggttcttt gctatgcga                469

<210> 149
<211> 487
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (481)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (482)
<223> n equals a,t,g, or c

<400> 149
cctttgtaac caaaggaaat aaactatttt ctctaycttt tawtttttca aaratattat     60
ttgactctat caaaagtctc tcctttttaa accttttctt atggatggct gtcaatcccg    120
aggcagaagt tttcaggtgg agaccaagcg gcctttgctc ttcttccttc ttcctgccac    180
actctgcttt cttcctgcca tggacccctg gaggagacct atggagggac agttttgacc    240
tgacccctag aggagacagt tttgacctct tcagcaccag gaaggaagct ctgaggatgg    300
ttgcagtgag gaagcatggg tctttaagga cttctctctc ttttttgctg gacattattg    360
agtttgtggg accctgcctc ttcctgctac ctgtgggtct gcccagagtc cctgcaggcc    420
tgtccatgca ttaaaaattc ctattgtctc tcaaaaaaaa aaaaaaagaa aaaaanaaaa    480
nnggaaa                                                              487

<210> 150
<211> 698
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (388)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (401)
<223> n equals a,t,g, or c

<400> 150
gcgccgctcc agccatgtca gcgcgcgcga gcctgggccc accatgagcc atggccatgt     60
ccgtgagcgc cgaggacgac gactatgaat cggagccgga ccagaaccgg gctgtgggtc    120
ggcccaaggg gaagctgggc ccggcctccg cggtgaagtt ggccgccaac cggacaacgg    180
caggagctcg gcggcgccgg acgcgatgcc gcaagtgcga ggcctgcctg cggaccgagt    240
gcggagagtg ccacttctgc aaggacatga agaagttcgg gggccccggg cgcatgaagc    300
agagctgcat catgcggcag tgcatcgcgc cagtgctgcc ccacaccgcc gtgtgccttg    360
tgtgttgcga agcggggaag gaagacangg tggaagaaga ngaaagcaag tttaacctca    420
tgctcatgga gtkctccatc tgcaatgaat catccaccct ggatgcctta aggtgagtgg    480
cccagtgggg acaggtggtg tgacgctctg gggcaggtag ggttgctgga gatgctggtg    540
agatggtggg atgcaggtcg tgcagtgaat tcctggagga cccctgagtc tgggtgatcc    600
tgtgtgtcaa gggataagcc cggggcaagg agggcctgga gtacctcaga gacccagtgt    660
catcaaagga ataaacacac ccccacctcc caggatgt                            698

<210> 151
<211> 612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (533)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (606)
<223> n equals a,t,g, or c

<400> 151
gccgcgcgca gcacgctcaa ggccgggatg gcggcggcgg cggcggcagg aagcgggacg     60
ccccgagagg aggaggtacc tgctggggag gcagcggcct cgcagcccca ggccccaacg    120
agtgtgcctg gggctcgtct ctcgaggttg cctctggcgc gagtgaaggc cttggtgaag    180
gcagatcccg acgtgacgct agcgggacag gaagccatct tcattctggc acgagccgcg    240
gaactgtttg tggagaccat tgcaaaagat gcctactgtt gcgctcagca ggggaaaaag    300
gaaaaccctt cagaggagag acttggataa tgcatagaag ctgtggatga tttgcttttc    360
tggaaggtac ttakattgat tgccgagcgg ggcattttkt gagcttcatc tgaagccttc    420
agttcacccc tctgcacagg cctcagcttt gaagaacgga gtctttgcac ttacacacac    480
tcttcctgtt ctgccttcac ctatgccggg ataagcagag atctcatcaa ttnagctctt    540
ctctgcaagg tcttccactt atttctgtct gtcttccata tcaagcctgg gatgcagctg    600
ctgctnttta tt                                                        612

<210> 152
<211> 646
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (566)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (588)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (603)
<223> n equals a,t,g, or c

<400> 152
gccctgtggc tcgcgccgtc ccccgccgcc cgtcgacccc gcttccatgt ccctggcgga     60
cacagctccc aggaacctcc acgcccatgg ccactaggca gagggaatcc tctatcacct    120
cctgctgttc cacctcgagc tgcgacgcag acgacgaggg cgtgcgcggc acctgcgaag    180
atgcttccct gtgcaagagg atattttgct cgagtccatg gtgtcagtca gcttataaag    240
gcatttctac ggaagacaga atgtcattgt caaattgtca accttggggc aggcatggat    300
accaccttct ggagattaaa ggatgaagat cttctcccaa gtaaatattt tgaggttgac    360
tttccaatga ttgtcacgag aaagctgcac agtatcaaat tgccaacact cctgatagct    420
gaatgtgtgc tggtttacat gamtccagag cagtccgcaa acctcctgaa gtgggcagcc    480
aacagttttg agagagccat gttcataaac tacgaacagg tgaacatggg tgatcggttg    540
gggcagatca tgattgaaaa cctgcngaga cgccagtgtg acctggcngg agttgagact    600
gcnagtcatt agagtcacag aaagaaccgc tcctgtccaa tggtgg                   646

<210> 153
<211> 522
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (488)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (495)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (512)
<223> n equals a,t,g, or c

<400> 153
tagtatcaca ttccttggga tgtgtaatta cttatgacat aatgactggc tggaatccag     60
ttcggctgta tgaacagttg ctgcaaaagg aagaagagtt gcctgatgaa cgatggatga    120
gctatgaaga acgacatctt cttgatgaac tctatataac aaaacgacgg ctgaaggaaa    180
tagaagaacg gcttcacgga ttgaaagcat catctatgac acaaacacct gccttaaaat    240
ttaaggttga gaatttcttc tgtatgggat ccccattagc agttttcttg gcgttgcgtg    300
gcatccgccc aggaaatact ggaagtcaag accatatttt gcctagagag atttgtaacc    360
ggttactaaa tatttttcat cctacagatc cagtgggctt atagattaga accattaata    420
ctggaaacac tacagcaaca ttttcacctg tccagatcca ctgggtacaa tacttnaaat    480
cctttacntt atggnacata tggaggccaa gnttttcttc aa                       522

<210> 154
<211> 593
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (153)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (155)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (158)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (590)
<223> n equals a,t,g, or c

<400> 154
ggcacgaggg gcactccccc gggagtgagg gttgctgggc ctgatgacgt ggcttggcaa     60
cgtccctacc gccgctgctt cccgggaacc tggcgccgcc ggaactgatc gcggcctagt    120
cccgacgcgc ctgcacccgc tgttccgcgg cangncgnag acatgaggag accccgcgac    180
aggggcagcg gcggcggctc gtgagccccg ggatggagga gaaatacggc ggggacgtgc    240
tggccggccc cggcggcggc ggcggccttg ggscgktgga cgtacccagc gctcggactg    300
cattttttat ggttttgttt caaaagccat tttcttctgg gaaaaytatt accaaacacc    360
agtggatcaa aatatttaaa catgcagttg ctgggtgtat tatttcactc ttgtggtttt    420
ttggcctcac tctttgtgga ccactaagga ctttgctgct atttgagcac agtgatattg    480
ttgtcatttc actactcagt gttttgttca ccagttctgg aggaggacca gcaaagacaa    540
ggggagctgc ttttttcatt attgctgtga tctgtttatt gctttttgan aat           593

<210> 155
<211> 601
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (477)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (549)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (582)
<223> n equals a,t,g, or c

<400> 155
cagcgtcccg tctttgagag atcatcctct ccactgcctg catgaaccgg gtcctcagct     60
tccacagcgt gtctggaatt ctggtttgcc aggcgggctg cgtcctggag gagctgagcc    120
ggtatgtgga ggaacgggac ttcatcatgc cgcagactta ggagccaagg gagctgccac    180
atcgggggaa acgtggcaac caacgctgga ggcctgcggt ttcttcgata tggctcactg    240
catgggactg tcctgggcct ggaagtggtg ctggccgacg gcactgtcct ggactgcctg    300
acctscctga ggaaggacaa cacgggytat gacctgaagc agctgttcat cgggtcggag    360
ggcactttgg ggatcatcac cacggtgtcc atcttgtgtc cacccaagcc cagggctgtg    420
aacgtggctt tcctccgtca cctgtgtgcc gcccgcctgt ggtcctggga acccgangcc    480
accccggctt gccgcatcct gctcttccca ctcccaagct tgccaagctt tgctgaaagt    540
tcctgcaana ccttccacac ctgcaaaggg aatgctnggt tnagatcctg tcttgcattc    600
c                                                                    601

<210> 156
<211> 602
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (554)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (591)
<223> n equals a,t,g, or c

<400> 156
ctgcaggggc atntccgctg ggccactgca gccatggatg ccgctgaggg ctggttgtgg     60
acagtggtca gctggttgtt aaaggtcatg gtcaggttgg tggacgtgct gggggccacg    120
tgcgtgatga aaggggtttw gctctggttc accgtgtcat acatattcac ccgacgcttg    180
cagatctcca tgttctggaa acatgatttg acgtgtgtgc tgtggggaaa atcgagtaag    240
tgtgtcatgg tgacaaaggg atggttcagg gtttcgattg gagtgattct cttgtcagca    300
tcaatggtca gcatcttctt caacaggtca atgaactccc gccggtcagc cttttctacc    360
aacatgtcgc tcccttccaa atctgtcgtc atgttcacct gggccatatc atctaaacag    420
ttgaaaatgt actttcttgc ttcttttgac ttaatccctg tctctgcttc atggtcatct    480
ggtgtcttca gtctccacaa aggatatggt gagtccgtgt cacggttgaa aaacctagtt    540
gtctttgtcc cggngcttaa taaatattca gcaggcaaac cctgtgtttt ntgaaatata    600
cc                                                                   602

<210> 157
<211> 1332
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (32)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (68)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1332)
<223> n equals a,t,g, or c

<400> 157
ccagaggtna gccagtgant acatgtctag ancatctagn aataaagctt gcatggatag     60
gaaaagcntt cccaggatgg aagaaaggaa ggaaagagct ttcttcgtcc taattaagca    120
ctcgtgaagt gcttaattgg agacagcaat ataatgagcc agggtgaact tggcccacaa    180
gccaagacag tgagagacaa atgttctcct tactcagatg atcgacatgc tgtactttgt    240
ggtcatcatg ctggtcgtgc tcatgagttt cggagtagcc cgtcaagcca ttctgcatcc    300
agaggagaag ccctcttgga aactggcccg aaacatcttc tacatgccct actggatgat    360
ctatggagag gtgtttgcag accagataga cctctacgcc atggaaatta atcctccttg    420
tggtgagaac ctatatgatg aggagggcaa gcggcttcct ccctgtatcc ccggcgcctg    480
gctcactcca gcactcatgg cgtgctatct actggtcgcc aacatcctgc tggtgaacct    540
gctgattgct gtgttcaaca ataccttctt tgaagtaaaa tcaatatcca accaggtgtg    600
gaagttccag cgatatcagc tgattatgac atttcatgac aggccagtcc tgcccccacc    660
gatgatcatt ttaagccaca tctacatcat cattatgcgt ctcagcggyc gctgcaggaa    720
aaagagagaa ggggaccaag aggaacggga tcgtggattg aagctcttcc ttagcgacga    780
ggagctaaag aggctgcatg agttcgagga gcagtgcgtg caggagcmtt ccgggagaag    840
gaggatgagc agcagtcgtc cagcgacgag cgcatccggg tcacttctga aagagttgaa    900
aatatgtcaa tgaggttgga agaaatcaat gaaagagaaa cttttatgaa aacttccctg    960
cagactgttg accttcgact tgctcagcta gaagaattat ctaacagaat ggtgaatgct   1020
cttgaaaatc ttgcgggaat cgacaggtct gacctgatcc aggcacggtc ccgggcttct   1080
tctgaatgtg aggcaacgta tcttctccgg caaagcagca tcaatagcgc tgatggctac   1140
agcttgtatc gatatcattt taacggagaa gagttattat ttgaggatac atctctctcc   1200
acgtcaccag ggacaggagt caggaaaaaa acctgttcct tccgtataaa ggaagagaag   1260
gacgtgaaac gcacctagtc ccagaatgtc agaacagtct tcaccttcac tgggcacaag   1320
cacatcagca an                                                       1332

<210> 158
<211> 437
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (364)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (377)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (412)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (415)
<223> n equals a,t,g, or c

<400> 158
cgcgtcgtag agttggggag cgggarggca acggcagcgg gatcgggatg aacagcggcg     60
gcggcttcgg tttgggctta ggcttcggcc tcacccccac gtcggtgatt caggtgacga    120
atctgtcgtc ggcggtgacc agcgagcaga tgcggacgct tttttccttc ctaggagaaa    180
tcgaggagct gcggctctac cccccggaca acgcacctct tgctttttcc tccaaagtat    240
gttatgttaa gtttcgtgat ccatcaagtg ttggcgtggc ccagcatcta actaacacgg    300
tttttattga cagagctctg atagttgttc cttgtgcaga aggttggatc tcgctttttt    360
tccncctatt gaattcngtc ctgtctgtaa tgccttagct tcctagagat tngcnagtag    420
acagtactcc tggggtg                                                   437

<210> 159
<211> 675
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (617)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (647)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<400> 159
gtggtttccg cccggcagcc cgcagcccgc tggccgccct tcgtctgggt ctccgccccc     60
aggacccgcg gccgagagct ccggagcgcg gcttccccgg ccggctgcgc gatgggctgc    120
gggaactcca ccgccaccag cgcgggcgcg ggccaaggcc ctgcaggagc agccaaagat    180
gtaacagaag aatccgtaac agaagatgac aagaggagaa actatggagg agtatatgtt    240
ggcctaccat ctgaagctgt caatatggtg tccagtcaaa caaagacggt tcggaaaaat    300
tagaagaaaa taacatcatg actcaagaat caagagcttg ctcatcagtt tggaaggaat    360
ttggctccgt gggacgttgt aatgtgcaca gacatttcca aggaaattct aaacagtcac    420
ccttcccttt tgcattcccc caaatcttaa gtgtatacat aaaaccctgg gtacatattg    480
ttgtggtaat agaagggaat tggttaaaca gtacacttgt ttatggract ttctgtggcc    540
acctacgaaa gacaagttac aamctscakg gaggcygttg ttgcccagcc aggggccgck    600
gcattttgac aacattncca ccctggccac tcagcacatt tcatggnggg catgccttnc    660
actgaacctt ttgat                                                     675

<210> 160
<211> 500
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (470)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (475)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (499)
<223> n equals a,t,g, or c

<400> 160
gcaactattc gttcatctgt gtagatgcca ctgtaaatcc agggcctaag agaccctata     60
atttctttgg aattttagat aagaaaaaga tggaggagct cttattactg gccaaggaaa    120
gcagtcggag caaccataca atttggtttg gacactttac aacatccact attctttctc    180
catcaccagg aatccggtca ataatgagtt cggctatagc ttatttgtgt ggacatctcc    240
atacacttgg tggactgatg cctgttttgc acactcgtca cttccagggc actttggaac    300
ttgaggtggg agactggaag gataatagga ggtaccggat ttttgctttt gatcacgacc    360
tctttagctt tgcagatttg atctttggga agtggcctgt ggttcttatc accaatccta    420
aatcactcct ttatagttgt ggtgaacatg aaccactaag aaagacttcn tcacnccaac    480
acacatcaga gtcctgggnc                                                500

<210> 161
<211> 585
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (519)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (530)
<223> n equals a,t,g, or c

<400> 161
agcgggtctt caagatgaca ttccaccact caatgacctt caagcagatc gtgctggttg     60
gtcaggagac ccagcggctc tactgctcct cacagaggaa ggaaagatct actctttggt    120
agtgaatgag acccagcttg accagccacg ctcctacacg gttcagctgg ccctgaggaa    180
ggtgtcccac tacctgcctc acctgcgcgt ggcctgcatg acttccaacc agagcagcac    240
cctctacgtc acagaccagg ggggagtgta ttttgaggtg cataccccag gggtgtatcg    300
cgatctcttt gggacccttc aagcctttga ccccctggac cagcagatgc cgcttgctct    360
ctmactgcct gccaagatcc tattctgtgc tcttggctac aaccaccttg gcctggtgga    420
tgaatttggc cgaatcttca tgcaaggaaa taacagatac gggcagctag gaacagggga    480
caaaatkgac cgagggggaa cccacacagg tttgtttanc tgcagcgggn ccatcaccct    540
gtgggtgcgg ggccttcaaa ccaattccct ggttgcttga ggcca                    585

<210> 162
<211> 1431
<212> DNA
<213> Homo sapiens

<400> 162
gggattggca agcttgcgtg ccccagcgac acaggcctcg aggctgtctc tgacaagtgt     60
tcacaggagg tggggacgcc tctgcgcgag gaacgaggag ctacgggcct gggcccggtt    120
attgccatgg gcagcggctg ccgcatcgaa tgcatattct tcagcgagtt ccaccccacg    180
ctgggaccca agatcaccta tcaggtccct gaagacttca tctcccgaga gctgtttgac    240
acagtccaag tgtacatcat caccaagcca gagctgcaga acaagcttat cactgtcaca    300
gctatggaaa agaagctgat cggctgtcct gtgtgcatcg aacacaagaa gtacagccgc    360
aatgctctcc tcttcaacct gggcttcgtg tgtgatgccc aggccaagac ctgcgccctc    420
gagcccattg ttaaaaagct ggctggctat ctgaccacac tagagctaga gagcagcttc    480
gtgtccatgg aggagagcaa gcagaagttg gtgcccatca tgaccatctt gctggaggag    540
ctaaatgcct caggccggtg cactctgccc attgatgagt ccaacaccat ccacttgaag    600
gtgattgagc agcggccaga ccctccggtg gcccaggagt atgatgtacc tgtctttacc    660
aaagacaagg aggatttctt caactcacag tgggacctca ctacacaaca aatcctgccc    720
tacattgatg ggttccgcca catccagaag atttcagcag aggcagatgt ggagctcaac    780
ctggtgcgca ttgctatcca gaacctgctg tactacggcg ttgtgacact ggtgtccatc    840
ctccagtact ccaatgtata ctgcccaacg cccaaggtcc aggactggta gatgacaagt    900
ccctgcaaga ggcatgtcta tcctacgtga ccaagcaagg gcacaagagg gccaktctcc    960
gggatgtgtt ccagctatac tgcagcctga gccctggcac taccgtgcga gacctcattg   1020
gccgccaccc ccagcagctg cagcatgttg atgaacggaa gctgatccca gttcgggctt   1080
atgaagaacc tcatcaggcg actacagaag tatcctgtgc gggtgactcg ggaagagcag   1140
agccaccctg cccggcttta tacaggctgc cacagctatg acgagatctg ctgcaagaca   1200
ggcatgagct accatgagct ggatgagcgg cttgaaaatg accccaacat catcatctgc   1260
tggaagtgag gctggtagtg actggatgga cacattgctg tgggtagtcc ctcctactag   1320
gaggcttgtc atactgtcta gaggttgact cttagttctg taaataaaga catccatttc   1380
aaacagccaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a            1431

<210> 163
<211> 668
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (198)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (566)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (575)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (579)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (590)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (632)
<223> n equals a,t,g, or c

<400> 163
agcctagtta cagattgcac tgcgtcagac tgttccacac ccagaagacg tcaggtgact     60
tcagtcctgc tgcagttgtg cagcagagga gactgcagac ttcggttgag gaaacgggta    120
tttcatgtct cagggagtag gtttgtgcag ttacagcttt tctgttggta tgcataatta    180
ataattggag ctgcaaanca gatcgtgaca agagatggac ggtcagaaga aaaattggaa    240
ggacaaggtt gttgacctcc tgtactggag agacattaag aagactggag tggtgtttgg    300
tgccagccta ttcctgctgc tttcattgac agtattcagc attgtgagcg taacagccta    360
cattgccttg gccctgctct ctgtgaccat cagctttagg atatacaagg gtgtgatcca    420
agctatccag aaatcagatg aaggccaccc attcagggca tatctggaat ctgaagttgc    480
tatatctgag gagttggttc agaagtacag taattctgct cttggtcatg tgaactgcac    540
gataaaggga actcaggcgc ctcttnctta gttgnatgna tttagnttgn attctctgaa    600
aggcttcttc cattttccac ttctttccag tngttttccc tgtttatttt tatgggaacg    660
ggccattt                                                             668

<210> 164
<211> 926
<212> DNA
<213> Homo sapiens

<400> 164
gttcgcaccc cctgaggacg atgagattga agagcatcaa caagaagacc aggacgagta     60
ctgagggcgg ccgcagccct ggctgactgc acggcttccc cgtgcctccc tccctgctcc    120
actcccacat tatagtcctt tcctaacacg gtcggccggg tgctttgtgt cagtsctgca    180
gcatggggga gccaggcgag gggggcttgg gggcatgggg ccggaaagca ggcagaagcc    240
cgtcctgggt ggtgctggcc cagttggtgg gacccctgtc cacacccacc ctatttattt    300
ccgttgtctc tctgctgtgt cgcccaacac ttcccagggt gctgctgcca cccgccccag    360
ccagccacct gctcctgaca gccagcagct gtgtatttga caaagtcatt ggtatatttt    420
tacttactgg attctccttg cactttacct gttcttttcc agagctgaca gcacgggctc    480
cggcgcagtg tgcctggctt ggcttccctt ccccatggct gggggctggg gtaggactca    540
cccattctaa tttattttgt cttttggctt ctcagtagct aaggggaagg ctgatgtcag    600
gagagggaga gggggctgag gaggtagtgc tgtaggccca gggggtcagg gaaagggagg    660
ggggcatgtg agggatggaa atgacctcct ggcaccaggc tcacccaccc aaggccccct    720
gccccagcac tgaatcccag cgctgccctg aggcccccag ccactccctc cagcagcctg    780
gttcaccaca caaactctgc ctggacccca ttgtctgtct gcttcccacc tgccctcccc    840
accccctgcc ctcgggcacc agcctgcata tgtgttcact tttatttaaa taaacttgtg    900
tggtaaaaaa aaaaaaaaaa aaaatt                                         926

<210> 165
<211> 799
<212> DNA
<213> Homo sapiens

<400> 165
ggcacgagct gaaggcttta ctcctggagg cgcagaaggg gcctgtragt ctcsaagagg     60
ccattcgaga acaggcgtct agctactccc gccagcagag ggacctccac aatctcatgg    120
tggacttgag gggcctggta catgctgctg ggccagggca ggactctggg tcacaggcag    180
gtagtccccc gaccagagac agagatgtag atgtcctttc agctgccttg aaagagcagc    240
ttagtcattc caggcaagtc cattcatgtc tagaaggctt acgagagcag cttgatggcc    300
tagaaaagac ttgtagccaa atggctgggg tggttcagct tgtaaagtct gcagcacacc    360
caggcctggt ggaaccagca gacggggcta tgcccagctt cttgctggag caggggagca    420
tgatcttggc actgtcagac acggagcaga gactagaagc ccaagtcaac aggaacacca    480
tctatagcac cctggtcacc tgtgtgacat ttgtggccac actgcctgtg ctctacatgc    540
tattcaaagc cagctaaccc ctggcccctc ctccagaggg tctgaggcaa tagctgtgaa    600
tgtggattta agtagagaat cgtagcaatg aagcgagcct ttgggggcat gtacaacctc    660
aatctgaagg agcagtatct gtgtggctca ccagcaggca tgctcgcttt gtagacaagg    720
ttcatttaca ttaattatca aaactttgtg ctaatgtcca attaaaatat cctgagtttt    780
attatttaaa acaaaaaaa                                                 799

<210> 166
<211> 563
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (282)
<223> n equals a,t,g, or c

<400> 166
aaataacaag atttttaatg cttgaatgat gattaatctt cagcattagc agatacttct     60
ttctttacac atggaccttt gctgcagtag aataaaaagg acaaacttct acctaaatta    120
ctccttattt tatgtatata ttttagcctc agaagttaag tattatttat cacacatgtg    180
ctttatatta tttgactttc atattaatct attcattgtg ctacttgata tttctagttg    240
tttaagaata attactgaat cccaatgggc ttgcaagttt tntttaacta aaatattttt    300
raccgtccac tactcaccta actctatata tgctaccata gtcctaatta aggaagttct    360
gcttttattt ttaagaaaaa ttcataagct tcagaatata atttaaaata ttttagagtg    420
aaaaatgagc actgaaaatt atacatggtc atgattttta aataaatttt tatccatgtt    480
taaggrtaat gtgtcaggca cattgatcta aaatgtaatt acgatgggta aatgttcaaa    540
tctaggatca gtgtgtaatg tgg                                            563

<210> 167
<211> 864
<212> DNA
<213> Homo sapiens

<400> 167
gggctgtggc ggtggcgctg gtggctgcgg cggcggcggc ggcagcggcg ctcgagcggt     60
tcctgtcagg gtcagccggc gggccccctg ggtggtccac ctgcaaatcg cggagcgcgc    120
cccagggatc gatggcgatg aactataacg cgaaggatga agtggacggt gggcccccgt    180
gtgctccggg gggcaccgcg aagactcgga gaccggataa cacggccttc aaacagcaac    240
ggctgccagc ttggcagccc atccttacgg ctggcacggt gctacctatt ttcttcatca    300
tcggtctcat cttcattccc atcggcattg gcatttttgt cacctccaac aacatccgcg    360
agatcgagat tgattatacc ggaacagagc cttccagtcc ctgtaataaa tgtttatctc    420
cggatgtgac accttgcttt tgtaccatta acttcacact ggaaaagtca tttgagggca    480
acgtgtttat gtattatgga ctgtctaatt tctatcaaaa ccatcgtcgt tacgtgaaat    540
ctcgagatga tagtcaacta aatggagatt ctagtgcttt gcttaatccc agtaaggaat    600
gtgaacctta tcgaagaaat gaagacaaac caattgctcc ttgtggagct attgccaaca    660
gcatgtttaa tgatacatta gaattgtttc tcattggcaa tgattcttat cctataccta    720
tcgctttgaa aaagaaaggt attgcttggt ggacagwtaa aaatgtgraa ttcagaaatc    780
cccctggagg agacaacctg gaagaacgat ttaaaggtac aacaaagcct gtgaactggc    840
ttaaaccagt ttacatgctg gatg                                           864

<210> 168
<211> 771
<212> DNA
<213> Homo sapiens

<400> 168
ttcagggcaa atcatctatg ggcttctttt aaatgcctca ccacatctgg acaagacatc     60
ctggaatgca ttgcctcctc agcctctagc tttcagtgaa gtggaaagga ttaataaaaa    120
tatcagaacc tcaatcattg atgcagtaga actggccaag gatcattctg acttaagcag    180
attgactgag ctctccttga ggaggcggca gatgcttctg ttagaaaccc tgaaggtgaa    240
acagaccatt ctggagccaa tccctacttc actgaagttg cccattgctg tcagttgcta    300
ctggttgcag cacaccgaga ccaaagcaaa gctacatcat ctacaatcct tactgctcac    360
aatgctagtg gggcccttga ttgccataat caacagccct ggtaaggaag agctgcagga    420
agatggtgct aagatgttgt atgcagagtt ccaaagagtg aaggcgcaga cacggctggg    480
cacaagactg gacttagaca cagctcacat cttctgtcag tggcagtcct gtctccagat    540
ggggatgtat ctcaaccagc tgctgtccac tcctctccca gagccagacc taactcgact    600
gtacagtgga agcctggtgc acggactatg ccagcaactg ctagcatcga cctctgtaga    660
aagtctcctg agcatatgtc ctgaggctaa gcaactttat gaatatctat tcaatgccac    720
aaggtcatat gcccccgctg aaatattcct accaaaaggt agatcaaatt c             771

<210> 169
<211> 977
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (863)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (865)
<223> n equals a,t,g, or c

<400> 169
acccacgcgt ccggaaccac gcatgggggc tgttttagca cagctgctaa aataggccag     60
gcctgcagga catacgggtc tgggagtgtg gcaaataact ggattgaaat ttataatttc    120
gtacagcaac ttgcggagag atttgtgagc cctgaaatga gattatcttt cattgtgttt    180
tcttctcaag caactattat tttgccatta actggagaca gaggcaaaat cagtaaaggc    240
ttggaggatt taaaacgtgt tagtccagta ggagagacat atatccatga aggactaaag    300
ctagcgaatg aacaaattca gaaagcagga ggcttgaaaa cctccagtat cataattgct    360
ctgacagatg gcaagttgga cggtctggtg ccatcatatg cagagaaaga ggcaaagata    420
tccaggtcac ttggggctag tgtttattgt gttggtgtcc ttgattttga acaagcacag    480
cttgaaagaa ttgctgattc caaggagcaa gttttccctg tcaaaggtgg atttcaggct    540
cttaaaggaa taattaattc tatactagct cagtcatgta ctgaaatcct agaattgcag    600
ccctcaagtg tctgtgtggg ggaggaattt cagattgtct taagtggaag aggattcatg    660
ctgggcagtc ggaatggcag tgttctctgc acttacactg taaatgaaac atatacaacg    720
agtgtaaaac cagtaagtgt acagcttaat tctatgcttt gtcctgcacc tatcctgaat    780
aaagctggag aaactcttga tgtttcagtg agctttaatg gaggaaaatc tgtcatttca    840
ggatcattaa ttgtcacagc cananaatgt tctaacggga tcgcagccat cattgttatt    900
ttggtgttac tgctactcct ggggatcggt ttgatgtggt ggttttggac ccctttgctg    960
caaagtggtt attaagg                                                   977

<210> 170
<211> 445
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> n equals a,t,g, or c

<400> 170
ggcacaggtt ccttccaaaa gctctgggag aatgttccgg ctctctcctg gcttctggca     60
gtgccagaat tccttggctg tctttggttc ctagatgctg cactccagtc tctgtctccg    120
tggtcacatg gtatcctctc cgtgcntccc tgcggcttca tgtgggcttc ttataaggac    180
accagtcact ggatttagga cccaccctaa atccaggagg acttcatcta tgagaatggc    240
atacacaaag agcctatttc caaatgaagt tcacattctg aggttctggg tgggacaggt    300
atttgttaag acactattta gcctagtcca tmctcattct tctacttcca agatggaatt    360
tcctaaactt ctaatagcta tttttatcac tgcagatttt attaccttga ccaaaaaaaa    420
aaaaaaaggg gggcccctta agggg                                          445

<210> 171
<211> 1581
<212> DNA
<213> Homo sapiens

<400> 171
ccatagactc tttggcatag actctttcgc aggcagccac tctgagtgtg gccagttcta     60
taaccatccc caaactagct ggagcctgat ggataggaac gggtagtctg tcctcttccc    120
cataaaaatg ttccaaaaag ttatctccag agagagtccc ttatgaagac agttgccaag    180
ctgtattctc attctttaaa ccaataccca ggtcagggct agttcacact agcactgtta    240
gggacatggt gtggctagaa atgaattgag tgtgacttct ccctacaacc ccaggcccag    300
ggataggagg aggcagaggg gtgcctggag tttctgcact ctcatcagtg atgttcatgt    360
tacacttgca caagggctga tttccacgta tgtgtgtgtt aatttattca cttagtttca    420
aaagattttc tctccccagc cattcagagg tttccaaact aagccactga gtttgagtca    480
gggaattcca cgtaaaaaga tcagattaag gtaaattctt tgttctgtat tgctgctgtg    540
acttcagaaa aaaaaaatta tgagagctct tcctggaatt ttgaaatttc tatttaatga    600
agaagtgtat aattccwtat ttattgtttg aggtttgatt tatctggarg cttaaaaaga    660
atgttttatt tttgttgtta ataaaatccc aatcacattt cacaataact aaaatgtctc    720
caggtgggtt actggtagat gatagtggtg acacctgcag gtctgcattt gaattggatt    780
cacagagaag cattccatgg tcacataatg aatagggaga acagatattt tcagaaaaat    840
caaccgattg ttttttccag aaacagaaca gaaaatgttc agaatatttt caaatttgtc    900
agattctttt atgtttcctt tgaaatttat tatttaagcc tattactaaa cctttataaa    960
aatatatttg gcaaatacac caaagaaacc agcttacaaa agattatgat cattaatgaa   1020
ctgcaaacct catctttcga aaacaaggtt ttgtgttttt ttttttttgt aaatatttgt   1080
gtttataaat gtacagcaga gtaagagtgt tttttagatt atttaattcc catatttcta   1140
aactatttac tacacagtaa tccatgcctg ttagtttgga ggacttgact gtctcatttt   1200
ttaattcatt gtcagtcatg cttggaacag catttccact agagaatcca gcgttctggc   1260
agtagcaaga gtacacatct ggagcatgag ggactctagc atgactcgtc agatgcacac   1320
cccaagagac aagaatgtgt agtttaatga ccggcgtgga ccatacgaaa ttgagattct   1380
aactttcctg caggagtgct catgagccca gaatgtgatt gggataaggc catttgccca   1440
caaatttagc tttcatgtaa ctcctagtgt gttatatcat aatgtatttt gttcttcctt   1500
tttaatgtaa gttttgcttt gggtcaattt gaattaaaaa aatcaaatct gaaaaaaaaa   1560
aaaaaaaaaa aaaaaaaaaa a                                             1581

<210> 172
<211> 440
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (415)
<223> n equals a,t,g, or c

<400> 172
ggcacgagct tgcacctcgg cgatccccga ctcccttctt tatggcgtcg ctcctgtgct     60
gtgggccgaa gctggccgcc tgcggatcgt cctcagcgcc tggggagtga tcatgttgat    120
aatgctcgga atatttttca atgtccattc cgctgtgttg attgaggacg ttcccttcac    180
ggagaaagat tttgagaatg gcccccagaa catatacaac ctttacgagc aagtcagcta    240
caactgtttc atcgctgcag gcctttacct cctcctcgga ggcttctctt tctgccaatt    300
cggstcaata agcgcaagga ataacatggg ttcgggagag atcttctcgg cggccggcgc    360
gctttcacga astcggggag cgacgatgca gtgcatcccg tggccgattc tctcngcggg    420
cgcgaatgga cggagaggaa                                                440

<210> 173
<211> 1395
<212> DNA
<213> Homo sapiens

<400> 173
cagctcagct ctgcgctgct gcacgccaac cacacactca gcaccattga ccacctggtg     60
ttggagacgg tggagaggct gggcgaggcg gtgaggacag agctgaccac cctggaggag    120
gtgctcgagc cgcgcacgga gctggtggct gccgcccgag gggctcgacg gcaggcggag    180
gctgcggccc agcacctgca ggggctggcc ttctggcagg gagtgcccct gagccccctg    240
caggtggctg aaaatgtgtc ctttgtggag gagtacaggt ggctggccta tgtcctcctg    300
ctgctcctgg agctgctggt ctgcctcttc accctcctgg gcctggcgaa cagagcaagt    360
ggctggtgat cgtgatgaca gtcatgagtc tcctggttct cgtcctgagc tggggctcca    420
tgggcctgga ggcagccacg gccgtgggcc tcagtgactt ctgctccaat ccagaccctt    480
atgttctgaa cctgacccag gaggagacag ggctcagctc agacatcctg agctattatc    540
tcctctgcaa ccgggccgtc tccaacccct tccaacagag gctgactctg tcccaacgag    600
ctctggccaa catccactcc cagctgctgg gcctggagcg agaagctgtg cctcagttcc    660
cttcagcgca gaagcctctg ctgtccttgg aggagactct gaatgttgac agaaaggaaa    720
tttccaccag ttggtggcac tgctacactg ccgcagccct gcacaaggac tatggtgcag    780
ccctgcgggg cctgtgcgaa tacgccctgg aaggcctgct cttcctgctg ctcttctccc    840
tgctgtctgc aggagcgctg gccactgccc tctgcagcct gccccgagcc tgggccctct    900
tcccacccag gaatccaagc gctttgtgca gtggcagtcg tctatctgag cccctcctcc    960
cggctggact ggagcctggc tcccctcttc gttccttccc tggctgccgg aggagacccc   1020
actaacccag cctgcctggg ctctgaccac taacactctt ggccatggac agcctgcaca   1080
ggaccgcctc cctgctcttg gccactgtgc tcccatttct gtccttggcc ttgggagtag   1140
ctgagggggc agactaggga gtagggctgg caggggaggg ggcagacagc ctcgcctcgc   1200
acccttcatc cctggctgcc ggtcccatcc ttggagggac taagctgggg gtgggggaca   1260
tgagtccccc tgctgcccct gccacatccc agtgggctct gaccccctga tctcaactcg   1320
tggcactaac ttggaaaagg gttgatttaa aataaaaggg aagactattt tacaagcaaa   1380
aaaaaaaaaa aaaaa                                                    1395

<210> 174
<211> 776
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (644)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (655)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (665)
<223> n equals a,t,g, or c

<400> 174
cgtgtcagac gtggcaagaa aaaccagcag ttgccttttc atctcttttc tgatgatcta     60
accatgaagt ccccagtatt tgagcattta aggcagaatg taaattcata atttaagaag    120
attttttgtt acgtggctag cccaggttga agaaatatgg agatcaacac aaaactgctc    180
atcagtgtta cctgtatcag ctttttcacc tttcagcttc ttttctactt tgtaagttac    240
tggttttcag caaaagtttc tccaggtttc aatagtctca gcttcaaaaa gaagattgaa    300
tggaactcaa gggtagtatc cacatgccat tctttggtgg ttggkatttt tggcctgkac    360
attttcttaw tcgatgaggc tactwaagct gatccacttt kgggtggtcc atcacttgca    420
aacgtgaata ttgctattgc ctcaggctac ctcatttctg atttgtccat tatmattttg    480
tattkgaaag tgattggtga caaatttttt ataatrcatc attgtgcgkc cctgtrtgca    540
tactrcyttr tactgatatt agtgaataag agtttaattt ggcataattt cttcaagatc    600
agatatatcg aaacatctct ccagaccacc catttggatc acgntataaa taatnataaa    660
aggtnttaaa actggtttca gttctttggg ccactggaaa tcaccaggct tagccctggc    720
tgtgccgtgg attggcaagc tggaaggttt aattaatgtg ggggggacct aataat        776

<210> 175
<211> 539
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (28)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (136)
<223> n equals a,t,g, or c

<400> 175
cgagaacgag gaggagatca tccgcaanat gcaggcgcac caggagaagc tgcagctgga     60
gcagttgcgc ctggaggagg aggtggctcg gctggcggcc gaaaaggagg cactggagca    120
ggtggcggag gagggnaggc agcagaacga gacacgcgtg gcctgggacc tctggagcac    180
cctctgcatg atcctcttcc tgatgatcga ggtgtggcgg caggaccacc aggaggggcc    240
ctcacctgag tgcctgggcg gtgaggagga tgagctgcct gggctggggg gcgccccctt    300
gcagggcctc accctgccca acaaggccac gcttggccac ttttatgagc gctgcatccg    360
gggggccacg gccgatgcag cccgtacccg gragttcctg gaargcttcg tggatgattg    420
ctggaagccc tgaggagcct ctgcaaccgg gacaccgaca tggaggtgga ggacttcatt    480
ggcgtggaca gcatgtacga gaactggcag gtggacaggc cactgctgtg ccacctttt     539

<210> 176
<211> 674
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (533)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (568)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<400> 176
gctcgtgccg aattcggcac gagaggacgc gggaggcgca cttgcttcaa gtcgcgggcg     60
tgggaacggg gttgcaaaac ggggcctctt tatccgggct tgcttccggc gtcatggctc    120
aaagggcctt cccgaatcct tatgctgatt ataacaaatc cctggccgaa ggykactttg    180
atgctgccgg gaggctgact cctgagttct cacaacgctt gaccaataag attcgggagc    240
ttcttcagca aatggagaga ggcctgaaat cagcagaccc tcgggatggc accggttaca    300
ctggctgggc aggtattgct gtgctttact tacatcttta tgatgtattt ggggaccctg    360
cctacctaca gttagcacat ggctatgtaa agcaragtct gaactgctta accaagcgct    420
ccatcacctt cctttgtggg gatgcaggcc ccctggcagt ggccgctgtg ctatatcaca    480
agatgaacaa tgagaagcag gcagaagatt gcatcacacg gstaattcac ctnaaataag    540
gtttgatcct catggttcca aatggaantg ctctatgggg cgaatagggt tacatctatg    600
gttcttcttt tttgttcatt aggaanttgg gagttggaaa agtttcctca aagccttttt    660
cagccggttt tgtg                                                      674

<210> 177
<211> 1424
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1224)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1261)
<223> n equals a,t,g, or c

<400> 177
gcggccgccc tttttttttt tttttttttt tttttttttt tcaaaatttg cttttattta     60
cacgtttgag tcaattacat gcatgtttta tttttgagga gtgattagca aaatgcatta    120
aaattttaaa atagcaatta aatatacaaa aatatagctt acaaaaaact gcgaatgttt    180
aaaaatattc tgctgcagaa tttttagtgt acaaagacgt ctatgaaacc tgaggttcag    240
catttcataa accttttttt gagggagtta cacaatacct agtgaggaaa cccgagggcc    300
aaactacaag acgaaaaagt gccccgttcc tggcaatgat gtcagaagac caagaggcga    360
tagttaccag caacactcta ggaagaccag ctgtcaccag aagggagttc ctaacacttg    420
ccacacctgc tcccccgacc gggggcctgg gagggaaggg cagatggaga ggaacggtgt    480
gcagtgggcg tgagatgcag atccaccagg cttgggactg gcaaagggag ctgagaagag    540
agttccccca aagcacaaac aagtctgctg acactggtgg ggcccttaca gtcacagaag    600
taaggactgg atggtaagcc aaaggtgctg atgcttggtc aaaaagtgga gtacatcttt    660
gcatcttgta acaatttggg ctctacagct gaattggcaa agtaaggttt actacacaag    720
cccctctttt tcttctgata tccccactca aatggaagca cactccccag cacatgggga    780
tcccttatta atctttacta aagaaccgtg aaccagcatt ttccagttat caactggata    840
tttaggcatg aatctggaca tgtccatctg cttaagaaat ctgcttaaga aatctgtaac    900
agctacagga aaagacacac ccagggccag akattctaca aatgccagaa gagtggatgt    960
gatagagaat tttttctcaa gttttgggtt agggcaccag ttgcaatttt aatccagggg   1020
aggatctggg ctgctgctgt agggggcaag tacaccaggg aggtgggtgt ggacagaggc   1080
actgggcagc tgctgggaag cgaggcacaa gtctgtgccc ctactcccag ggctgcctgg   1140
aggaagcagc tctaactttc atcagcgggg acaaaaatga acttaaacta aaaaaattat   1200
tggccgggcg cagtgctcac gccngtaatc ccagcacttt gggaggtcaa ggcgtgagcc   1260
ntcgcgcccg accagaagca ttttcttttc aaagtgtgtg cacagagtga ggaggccagc   1320
ctgggcaaca tagtgagttg agacctgtct ctacaaaaaa ataattacga aaattagcca   1380
ggtgtgctgg tgtgcacctg tagacgcagc tacagactga ggcg                    1424

<210> 178
<211> 507
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (43)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (464)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (483)
<223> n equals a,t,g, or c

<400> 178
agggcnactg gaatacccaa acaaacagaa aatactccca tantaccatc gaggttttaa     60
aaaaaactcc ccaaaataca agtcttcata ggaaaatgtc ttttattgcg cgacatgaag    120
catccgttat ttgcgtgctc aggaatagaa gggcctccct ttctcaggag tctgaagtct    180
gtycagcctc gcaacctgag aaggggaggg gggcacatct tgccggaagg ccccttggga    240
ggggcgtaac tggggtcctg gactttctta tacgagtcat agttgctggg cccctcggaa    300
ggaggctgct tcttcatctg ctgctccttc cgcctctgty cctggcgaag gagctcctga    360
gtttccagca tgaccctggc gttgaagcca tgtcctccca gtagccgttc ctggagcctt    420
ggtagctgga gtacctgggg tctctttggc atctggaagc cttncccagg ggagtagtct    480
gcncccaaga gtctgggaga ccgagtg                                        507

<210> 179
<211> 1166
<212> DNA
<213> Homo sapiens

<400> 179
actctggtgc acgwgtatgt caatgaaagt gtttctaatg caactgcgat tgactcccag     60
atagctagaa gtttgcacat cccactcacc caggatatag ctggtgaccc aagctatgaa    120
attagcaaac agagactcag tattgtcatt ggcgtggttg ctggcattat gacggtgatt    180
ctaatcatct taattgtagt gatggcaagg tactgcaggt ccaaaaataa aaatggctat    240
gaagccggca aaaaagatca cgaagacttt tttacacccc aacagcatga caaatctaaa    300
aagcctaaaa aggacaagaa aaacaaaaaa tctaagcagc ctctctacag cagcattgtc    360
actgtggagg cttctaagcc aaatggacag aggtatgata gtgtcaatga gaagctgtca    420
gacagcccaa gcatggggcg atacaggtcc gttaatggtg ggcccggcag tcctgacctg    480
gcaaggcatt acaaatctag ttccccattg cctactgttc agcttcatcc ccagtcacca    540
actgcaggaa aaaaacacca ggccgtacaa gatctaccac cagccaacac atttgtggga    600
gcaggagaca acatttcaat tggatcagat cactgctctg agtacagctg tcaaaccaat    660
aacaagtaca gcaaacagat gcgtctacat ccatacatta ctgtgtttgg ctgaattcca    720
ctctaatatg atgctccayt atgcaccata ctgtgatgac ctttctactc cgaaacctgc    780
tggagcctgc ccttggccgt ggggtgtcag ccaatcactg cttgttccac ttgttgtaca    840
ttttattttt gagtcttttt ctttctcata tacagaaaaa tagtatgaaa ataaaataaa    900
tgtatgaaac agtattaatg cagaaatgtg ctactaatgg atgtctgagt caccagaaat    960
tccattctta aagaggcggt tagcacctat tagacgtaac agtgatgtct tttaaaaaat   1020
ccaaaagcat attgcaacaa taagtttgag actttgtgtg aacaaaggga aattcagcct   1080
cttatgtctt tgtctttaat acattaaata ctgattttga ataaaaatct aaattgatca   1140
ataaaaaaaa aaaaaaaaaa ctcgta                                        1166

<210> 180
<211> 730
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (660)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (661)
<223> n equals a,t,g, or c

<400> 180
cagcagtgca tccagaccat ctccacactg cacgatgatg agatcctgcc cagcaacccc     60
gctgacctct tccactggct gcccaaggga gcacatgtgt gtgcttgtct acctggtgac    120
tgtgatgcac tccatgcagg ccggctacct ggagaargcg cagaagtacw cggacaaggc    180
cctcatgcag ctggrgaagc tcaagatgct ggactgcagc cccatcctgt catccttcca    240
agtgatcctg ctggagcaca tcatcatgtg ccgccttgtc acgggtcaca argccacggc    300
gctgcaggag atctcccagg tctgccagct gtgccagcar tccccccggs tcttctccaa    360
ccatgcagca cagctgcaca cattgctggg cctgtactgt gtctctgtca actgcatgga    420
caacgcggaa cccagttcac cacggccctg cggctcacca accaccagga gctgtgggcc    480
ttcatcgtca ccaacctggc gagtgtgtat atacgggaag gaaatagaca ccaagaggta    540
ctctacagtc tgctggagag gatcaacccg gaccacagct tccctgtcag ctcgactgcy    600
tcgacagccg cttctatgtg cgtggctctt ctctcttcag ggacgtcaac gaggcaagcn    660
ntctgcggaa acttgaaagt caatgtgaga ctgaccggta agctgtctcg gtttggcaat    720
tttatggtgg                                                           730

<210> 181
<211> 1243
<212> DNA
<213> Homo sapiens

<400> 181
gttctcctgc ctcagcctcc caagtagttg ggattacggg catgcaccac catgcctgga     60
taattttttc ttatttttag tagagacagg atttcatcat gttggccatg ctggtttcga    120
actcctgacc acatgtggtc cacccacctt ggcctcaatt atgtgcattt tggtatattt    180
acttgtattt caacatcttg tgagtttgaa aaacctgaaa ggccagaatg cttcctttta    240
tttctcacca tttgggcagc acctaagtgg ttttgtaaaa tgcagcatct ggtgctgtgg    300
gtctctctca ggccttgagg gacacttcct tcctccccac tcgcctcctc tccactagac    360
tttggttcct agagggcgtg gggccgggtc tgaggttctt gcctgccttc cctcccattg    420
gtctttggtt gctcatccct ctaactgcac cccttcttgg tccttcctcc acagacttca    480
gataatagat aagtcattag caaaccagac cgaatcttta gggtgaagag ctccccaaag    540
ccatctggtg aggtcattgt ggggaccagg gactgattat ttgtcacctg gatcacaaag    600
atgggactgt ctgctcaggc tggtggtgac aggatcctga cccgtggtcc tctcccgctc    660
cctctgctcc accaggacac atgtatagga cactgtgctg tgtgcagtgg agaaatctcc    720
ctgggccagg ggaaagttca gacagtgcct ctagattgtg ttttgcctcc tccaatgtag    780
agttgacatc tggaccccag agcccagcag ggytttctgt cagacatgct agggtggtag    840
aaatgggccc tccaggtccc cctgcagtgc actgggcaga gacctccgga aagccggcag    900
cgggagcgct tcctgggcag cttcccccag cacagtgttc ccaaaccagt ccatccggaa    960
aacagtctgt acagcaaatg ctgtgtgaga tcttaggctt ttcacttttt ttgttttgtt   1020
ttgtttttga aagaaagaaa aaaatacaat taacaagcct cttttgtaaa tgggtttcct   1080
ttctatgtat aaaatcgtgg tggtcccttg tttttacatg ttcatgctgt gtaattttga   1140
gatgttactg agatatgttc tgaacataat gtgcattttt ttctgtacag atgaaatggg   1200
agaatttaat aaagagtttg caggttttaa aaaaaaaaaa aaa                     1243

<210> 182
<211> 394
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (365)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (389)
<223> n equals a,t,g, or c

<400> 182
aacaggagga aacagttagg gaataatgag cctggaggtg taaagtgcca caggatatat     60
gctgtacaca atttatttgg cacaacagat aatcgcttta attgaattca aaagtgcatt    120
gttcagcagc actgtggccr ctcacgcctg gggactgaga ctgtttggaa ggtttcagcc    180
tgactcttcg gtgcctctcc tcccctccct gcctctcccg gccctccgaa gtcctctggg    240
cctggagtca gacctcggct gggggcgggg caggggattc ctgggggtct cttcctctgc    300
tgtcagtgtg ccccttgcct tccgtttctt ccttcctttt ctcctgggga tgggtctgtt    360
ggcanctggg ggatgaggat gtgagacant ggcc                                394

<210> 183
<211> 658
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (627)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (634)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (635)
<223> n equals a,t,g, or c

<400> 183
catcattggc gcggggctgt cagcggccgg acgcggtcct ctacgcccgc cactacaaca     60
tcccggtgat ccatgccttc cgccgggccg tggacgaccc tggcctggtg ttcaaccagc    120
tgcccaagat gctgtacccc gagtaccaca aggtgcacca gatgatgcgg gagcagtcca    180
tcctgtcgcc cagcccctat gagggttacc gcagcctccc caggcaccag ctgctgtgct    240
tcaaggaaga ctgccaggcc gtgttccagg acctcgaggg tgtcgagaag gtgtttgggg    300
tctccctggt gctggtcctc atcggctccc accccgacct ctccttcctg cctggggcag    360
gggctgactt tgcagtggat cctgaccagc cgctgagcgc caagaggaac cccattgacg    420
tggacccctt cacctaccag agcacccgcc agragggcct gtacgccatg gggccgytgg    480
ccggggacaa cttcgtgagg tttgtgcagg ggggcgcctt ggctgtkgcc agctccctgc    540
taaggaagga acagaaccac ctacatcgcc aaccctggtc cagcctraga ggaatacatc    600
ctctgatcga cctcaaatcc ggagttnccc cttnncttgt caaattgacc gcccaata      658

<210> 184
<211> 947
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (353)
<223> n equals a,t,g, or c

<400> 184
ggccacgggg aaaaaccaac aaaaaagcac aaaaaagaca aaaaggaaaa aaagaaaaaa     60
aagaaagaaa aagagaaagc cgaccgggag gtacaggcag agcaaccatc ctcttcgtca    120
cccagacgca agacagtaaa ggaaaaggat gacactggcc ctaagaagca cagcagcaag    180
aactcagaga gagctcwgaa gaaggagaaa cccaagcacg agcacaagtc ctcaagcagg    240
agggaggcaa gagaagaaaa gaccaggatt agggacagag ggcggagctc agatgcacat    300
tctagctggt ataatgggcg ttctgaaggg cgtagttata gaagtagaag tangagccga    360
gataaatccc ataggcataa aagggcccga cgctcccggg agcgggagtc ttcgaatccc    420
agtgaccgtt ggcgtcactg aagacttcag ctgcacagta gatttggaaa taattatgtt    480
ttttaaatgc agtcaaattc agttgggtgg ttactatttt tgtatctaaa acttctgggg    540
ctggattctt ttaatcccyt gactatttag agtcattggg agggctgcag tttcaacagc    600
tagatatcct ggatattgtt tgcaccatcc attgtccctg taccagagta tgtatcctga    660
actttggttc ataaatatgg ctcttgaacc catagacccc agttgaagat ggaattttca    720
ggaaagggaa aatactagat aattctagaa ttctagtctt cgtgttagat gtttatagcc    780
cagcatcttg ggacctttcc agttactagg tttggacagc ttgatgtgaa cgaatgggat    840
aggattttta aaatcagcca gctccatgcc caaaccttcc tgtttgcaga actttttaat    900
gtcytttcyt tttcattaaa acttttttgt tcgatatgcc tctttcc                  947

<210> 185
<211> 486
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> n equals a,t,g, or c

<400> 185
ttgccctcag tgcaactcgg tgtcaatgtc tgagcctggt gtttatgccc cmactgctgt     60
ccyaaagtcc cytggcgarg ggargtggag gagctgcccc gtgggtgttt ggagattctg    120
ttttactctg cctnagagag gaaacggctt tggggaggga gggggaagcc tttattcttt    180
actgttgtcc ctgttttcct ttgggggaat ttactcagtt agcagcccct cctcaccatt    240
ccccccagga aggccatgtc ccagttttct gtccacccct cctgttcctc tgcactatgt    300
ctctgatttt ccctgccagg gaagctaacc cagagcacgc acctgtgctc atgagtgttt    360
ccgcaggata attcgttctg agcatgatac cacagtgtgg attgtctgtc tgtaaggaga    420
tgccatctac taaccaattt gtattgtgtt tccaataaat tcctggaaat ttaaaaaaaa    480
aaaaaa                                                               486

<210> 186
<211> 603
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (464)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (560)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (581)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (591)
<223> n equals a,t,g, or c

<400> 186
gggtaacttg gaatctcagc taacctctga gagttactat aaagaaaccc taagtgtccc     60
aacagtggag cacattattc aggaacttaa agatatattc tcagaacagc acctcaaagc    120
tcttaaatgc ttatctctgg taccctcagt catgggacaa ctcaaattca atacgtcgga    180
ggaacaccat gctgacatgt atagaagtga cttacccaat cctgacacgc tgtcagctga    240
gcttcattgt tggagaatca aakggaaaca cagggggaaa gatatagagc ttccgtccac    300
catctwtgra gccctccacc tgcctgacat caagtttttt cctaatgtgt atgcattgct    360
gaaggtcctg tgtattcttc ctgtgatgaa ggttgagaat gagcggtatg aaaatggacg    420
aaagcgtctt aaagcatatt tgaggaacac tttgacagac caangtcaag taacttggct    480
ttgcttaaca taaattttga tataaacacg acctggattt aatggtggca catatattaa    540
ctctatacaa gtaagtcagn gcttcctaca gataatcccg naactgtggg naaatcctaa    600
ggg                                                                  603

<210> 187
<211> 3303
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3107)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3139)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3166)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3168)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3178)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3224)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3239)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3265)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3267)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3273)
<223> n equals a,t,g, or c

<400> 187
ttccnggatc ttagggancc gcttttcggg ccatggccaa ccgtattcgc ggcattttcc     60
agtagcgggg aatttttcca gcatgcgaca ggaggaagta actctttgat ttctttgatg    120
cgtaaatcgt cgttctgata attcatgtct gttccagtgt tgccatactt atcttagtga    180
atgcaatact tccaatctat atcttccgtc agaatgtgta aacggggttt tacactatga    240
acggattaat cctggaatta gcaagaaaaa cgccagattg tcgcgaaaaa cgagatctct    300
cctacaattt ctaactgtaa ctcctttgtt tgttaattat ttcaagattc tctgctgcgt    360
ttcataacct ggctgaaatc ttaaaccaat gccttatatt cacctgcaaa tgcactgttg    420
gaagaggtta tccgacataa cgaccataac aggagcatcc tatgaaaatg acaaaactgg    480
ccacattatt tctgactgcc actctaagcc ttgccagcgg tgccgcactg gctgccgata    540
gcggagcgca aactaataac ggccaggcaa acgccgcagc tgatgcgggc caggtagccc    600
ctgacgcccg tgaaaatgtc gcgccaaata acgtcgacaa taacggggta aataccggtt    660
ctggcggcac aatgctgcat tcggatggtt cttcaatgaa caatgacgga atgaccaaag    720
atgaagagca caagaacacc atgtgcaaag atggtcgctg tccggatatc aataaaaagg    780
tacaaaccgg tgatggcatc aataatgatg tcgataccaa aaccgacggt accacgcagt    840
aaccctgcaa aatagccaat aatgggagag cggagtctct cccttttaat ttttcacttc    900
taaaagcagt atgatgtcat aaagttaagt gagaataatt aagggatgac tcgtcatggc    960
gcactcacac tcacacacgt cctcacacct gccagaagat aataatgctc gtcgcttgtt   1020
gtatgctttc ggcgtgactg ccgggtttat gctggtagaa gtcgttggtg gttttctttc   1080
tggttctctg gcattgctgg ccgatgcggg tcatatgttg accgatactg ccgccctgct   1140
tttcgcccta ctcgccgtgc aattttcacg tcgtcctccc accattcgcc acactttcgg   1200
ttggctaaga ctgaccacgc tcgcggcgtt tgtgaatgcc atagccctcg tggtaattac   1260
cattttgatt gtctgggagg cgatagaacg cttccgcacg ccgcgtccgg tcgagggcgg   1320
catgatgatg gcaattgccg tggctgggtt gctggcaaat atactttctt tctggttact   1380
tcatcacggc agcgaagaga aaaacctcaa cgtacgagca gcggcactgc atgtgctcgg   1440
ggacctgctg ggttcggttg gggctattat tgccgcgttg attattatct ggactggctg   1500
gacacctgct gaccccattc tctcgatact ggtgtcgctt ctggttctgc gtagcgcgtg   1560
gcgactgttg aaagatagcg tgaatgaatt acttgaaggt gcaccggtat cgctggatat   1620
cgctgaactg aagcgtcgta tgtgccggga aatcccggaa gtccgcaatg tgcaccatgt   1680
acatgtatgg atggtaggcg agaagccggt gatgacgttg catgtgcagg tgatcccgcc   1740
acacgatcac gatgccttgt tggatcagat ccaacactac ctgatggatc actatcagat   1800
tgagcacgcc accattcaga tggaatatca accttgtcat gggccagact gccacctgaa   1860
tgaaggggtg tctggccatt cacatcatca ccattaatgg gacagcgcgc gtgagcctct   1920
ttcacgtgcg ctgttgatcc acatccggct gccgttgagc gcaataaagg tcaggatgat   1980
gtactccaga gacatggcgt aaacgccctg aagtgcaaaa ataacgacgc taatcacgtt   2040
aataatcacc cacaacagcc agttttccac atacttacgc gtcatcagaa tcattgccac   2100
gatagataac accatcatgc atgaatccca gaacgggaaa gcgtccggtt gcagttcagg   2160
catcacaacc tgtaatccta atgcttgcat gatcatgact gccacgcggg tcaaaaatgc   2220
aaacaccgga ttgataaata ccgtcattca gaccaatcga aacaacgcaa accgccaacc   2280
agctgagtgg ccttcggcaa tggcaaccag cgaattttca actccgcctc gttctgactg   2340
gtttgtcgcg accacgcata ccaaccgtaa atattcgcgg caaagaaaaa cacctgtaat   2400
agcaggctgg catacagctg aatctgaaag aaaataatgc caaacaaggt gacgttgatc   2460
aggccaaaga agtagttgct gatcttctcc agactggcaa ggccaataca cagcaacccg   2520
gcgatcgtgc ctaccgcttc gatccatgag agatcataac cgcctgcccc tattggtata   2580
tgtaccagga tattctgcac actaaaaaaa tccatctttc ccccaaagcg taacgttacg   2640
ccttattatt cgttatccac gtagtgtagc cgcaaaatcc agcatacgat tgagcggcac   2700
cagcgccctc tctcgcagcc tttcatcaac atgaacctcg tgattgcttc cttcctgttc   2760
taatgcctct ggcgatggcc tgaaggccat tcatggccat ccacggacaa tgcgcgcagc   2820
tgcggcaggt tgcaccctca ctgcggttgg tgcttccagt aactctttat ctggcaccgc   2880
ctgctgcatt ttgtagaaaa taccccgatc ggttgccaca ataagcctct gatgtggcaa   2940
tgttttcgca gcagcgatca gttgactggt ggaacgaccg catccgccat atcgacaata   3000
gcttgtggtg attctggatg caccagtatg gcagcatccg ggtattcttc ttgcaagcgg   3060
gttaacgcct ggagtcttaa attcatcatg cacaataaca ggcaccnggc cagcattaga   3120
aatgttctcc aacccgtcng gttttttggc aagttaaagg ccccanangt tttgttcngg   3180
tggcccagat ggattttttt caacccaaat tattcaagat gganccatta agttcgaang   3240
gcaaagcttg gaagttaacc acccnanttt ggnggggggc tttttaccgc agcaaaaatg   3300
gtt                                                                 3303

<210> 188
<211> 844
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (711)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (721)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (733)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (779)
<223> n equals a,t,g, or c

<400> 188
acggcaccgg ctccataggt gcggctctgg ggcctctgct ggctgggctc atctccccca     60
cgggctggaa caatgtcttc tacatgctca tctctgccga cgtcctagcc tgcttgctcc    120
tttgccggtt agtatacaaa gagatcttgg cctggaagtg tcctgagcag aaggcagcgg    180
gtataaagaa atatgaggcc ccaattggaa cagcagcatg gagggtccca gttgggtccc    240
caacgtgctc cccatgggca agacaatgga aacttccaca agcagggaag gcaaaccctc    300
tttattgaac attagccagc ccagcccaga ccccagggct gctaaggaca cagagattct    360
ccatgggaag gggactgcca agcatgagga aatagaagak tcaggggcct gagctctgga    420
agctgcaagc aaaagggatg ggactagggc tgagttgtgt ctccattttg ataaggaaag    480
gatatgctca gactcttgct tgttcagatt ccaagacaga aggcttcaca aggccaacgc    540
ctggaaaatg ggcatctctc cttcccatgt taagctttaa cctctgtaat ctgcctgtat    600
ctataggtgg gcatctcact ccaccaaagg agcccagcct ctctttgtcc ctctatccat    660
gcaacagtct tctctgtgca tttccccaag ctgggccctc ttctactctc ncatttttaa    720
nggccttgat ttngggaata cctacgctat gtgtctcagg gcagactcgg gcgaagcang    780
ggagctgcct tcggtacata atttgaaggg gcactccctc ttggggcaca tgcccggccc    840
tgag                                                                 844

<210> 189
<211> 629
<212> DNA
<213> Homo sapiens

<400> 189
tcgacccacg cgtccgccca cgcgtccgaa gaaaccctaa gtgtcccaac agtggagcac     60
attattcagg aacttaaaga tatattctca gaacagcacc tcaaagctct taaatgctta    120
tctctggtac cctcagtcat gggacaactc aaattcaata cgtcggagga acaccatgct    180
gacatgtata gaagtgactt acccaatcct gacacgctgt cagctgagct tcattgttgg    240
agaatcaaat ggaaacacag ggggaaagat atagagcttc cgtccaccat ctatgaagcc    300
ctccacctgc ctgacatcaa gttttttcct aatgtgtatg cattgctgaa ggtcctgtgt    360
attcttcctg tgatgaaggt tgagaatgag cggtatgaaa atggacgaaa gcgtcttaaa    420
gcatatttga ggaacacttt gactaatagg agttttaagt atgttaaaaa tctatactgg    480
acagttacaa gaaattaccg gagaaaagct tgtgagctca ccaaacaagg atttcagtgt    540
agattttgtc tttcttgaac ttaaagaaac aaatgaccaa gtttgaatgg aaaagcctgc    600
tgttgttcca catctcgttg ctgtttaca                                      629

<210> 190
<211> 484
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (441)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (447)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (474)
<223> n equals a,t,g, or c

<400> 190
gctccgccac ccgccgccat gagtagcttt ggagctggca aaaccaaaga agttatcttc     60
agtgtggagg atggctccgt gaaaatgttc ctgaggggcc gccctgtgcc catgatgatc    120
ccagacgagc tggcacccac ctacagcctg gacacacgct cggagctgcc ttcttgccgg    180
ctcaagctgg agtgggtcta tggctaccgt ggccgagact gccgggccaa cctttatttg    240
ctgcccaccg gggagatagt gtactttgtg gcctccgtag ccgtgctata cagcgtggag    300
gagcagaggc agcgacacta cctgggacac aacgatgaca tcaaatgctt ggccatccac    360
ccagatatgg tcaccatcgc camgggamar gtggcgggaa ccaytaaggg aggggaaccc    420
ttgcggccca agtgggattt ngggaanatt ttcctttcac ttaaaagttt gggnttgggg    480
tttt                                                                 484

<210> 191
<211> 493
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (431)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (449)
<223> n equals a,t,g, or c

<400> 191
gtgagggact gganggagtc ggagaaaaag ctgacctaat gaaactgtgc aacngtcagc     60
gcttgaggct tgaagaggga gacaagctaa aagaggatat ccagttgttt catgatggca    120
tttgcacctc caaaaaacac agatggtccc aaaatgcaga caaagatgag cacctggaca    180
cccctaaacc atcagctatt gaatgaccgg gtatttgaag aaagaagagc cctgcttggc    240
aaatggtttg acaaatggac agactctcaa agaagaagaa tcctcacagg cctgttggag    300
cgctgctcgc tgtcccagca aaagttctgc tgtcgaaagc tttcaagaga aaattcccag    360
cagaagccct gggactttta caacccaagc tttccaaggg tgttatcctt tatacatctt    420
tttcttttcc ngggaaccct cgggagccnt ttgttcgttg tggcacaggt taaagggcca    480
agggaagggg gta                                                       493

<210> 192
<211> 1427
<212> DNA
<213> Homo sapiens

<400> 192
aatttttttt tttttttttt agtttgttta aagactttat ttgaaaccaa tgtcacagca     60
cgttagtcat aaaaatcatc agaatcatcg gtgttatggt ttctggggcg taaagcagcc    120
tcaatttctg agttactgtc atcagactca tcccagaggg ctggaaaata aaaccagaca    180
gttatttaac atttttgcat tctggttaag agcttacaaa acagcacagc acggaaggac    240
tggttaagca gagtgtcagt ctgcaaaatg cataacaggg acaccacatg atgtacctga    300
ccagacacac ccaaatgcat gtcatactgc acaaattaca cattgcaaag tgtgtcctct    360
gcactgttat gggaaaacaa tttgcagaat acttcctttt cccttctgtt gtgcccaact    420
ctttattata ggatagggat ttaaggtcag ggttacatgg aagcagggtt ccctggggtg    480
ttgtatcagc ctgatgccgc cccacctcag ctgcccctcc actttcatct cccattcttc    540
tttatgagag cagagaggag aagggaaaga cgtggcagag gaataagcag agatggttac    600
cctgagacag gactttggtc cacatcattt acttgagagg tgatcccagg aaccatgggg    660
acagtgacac aaggaagaca ggaagccaat gaagggtatg atgacgagtg ggtgcctggc    720
agtgagtgga caggcaaggc tcagcctgct ggggccccct gagagactgc agaactctcc    780
ccagattgtc ccagtgaaga gcaaggragt ggggttamtg atccaccaac ttgcctctgt    840
tggttgaggk ttgctctcaa cccagggcat caactccctg gtactttggg ctgccttgtg    900
agggctgagc acgctcctgc agccagagaa agccctcagg cagagagaca cagctgcttg    960
gtgcaggaag ctgtaggcgc gtctgtgaat tggagctgag gtgccctgca ggtggtctgg   1020
caaggtgtag tggagcggac cacgtctact acatcaacaa tcccttaact ctgctgacac   1080
ctgcatggca ccacctgcca gctctgtgct gacttctcat acacaacccc atctcatcct   1140
cgcaccagcc tggcaaggta agtattaatg tttccatttc actgtgcaaa caaacggacg   1200
ctgaaggggg ttaagaaatt ggccacaatc acaatgccag tgagtggcca agctgggagt   1260
cccatccaag tcatctgact caagcccata ctctccatca caaccactgg gtacttgtct   1320
cccccacagt aggtagctgt ccttctagaa gagtgattca cagtggggtg cttgctaaaa   1380
aggcagattc ctaggcctag gttctacagc agctctgaat cagtttc                 1427

<210> 193
<211> 841
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (773)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (815)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (830)
<223> n equals a,t,g, or c

<400> 193
cccacgcgtc cgagccccca agatggcggc acggcggagg agcggatggc agaggaagga     60
ggcggcggcc aaggcgacgg cggttcctct ttggcctccg gctctaccca gcgacagcct    120
ccaccgcccg cgccacagca cccgcagccg gggtcccagg cgctcccagc ccccgcgctg    180
gctccggacc agctgcctca aaacaacacg cttgtggcgc tgcccatcgt agccatcgag    240
aacatcctca gctttatgtc ctacgacgaa attagccagc tccgcctggt ttgtaaaaga    300
atggacttgg tctgccagag aatgttgaat cagggatttc tgaaagtgga gaggtaccat    360
aatctatgtc agaaacaagt taaagcacaa ctcccaagga gagagtcaga aaggagaaac    420
cattcattag ctcgtcatgc agacattctt gctgctgttg aaacaaggct gtcactatta    480
aatatgactt tcatgaaata tgtggattcc aatctctgtt gcttcatccc aggaaaggtg    540
attgatgaga ttwatcgkgt gktgagatat gtcaattcta ccagagcccc tcaacgagct    600
catgaagtac ttcaagaatt aagggatata tcctctatgg caatggagta ctttgatgaa    660
aagattgttc caattttaaa gaggaaatta ccaggatcag atgtttctgg aagactcatg    720
ggttctcctc cagttccagg accgtctggc agccctaaca acaatgcagc tcnttcttcc    780
aagcaaaatc cttcaagaca agaggtttac caaantcccg cagccggttn aaaacaatgg    840
g                                                                    841

<210> 194
<211> 443
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (355)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (360)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (434)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (439)
<223> n equals a,t,g, or c

<400> 194
tgcnttgttg catgcactta atgaagttga tcctggtgac tggcagaaat tcgtgaagaa     60
gggactcaaa tttcggtacc aggaccacac atttttaaag atgctcctca ccgccgtaca    120
gctcctgtac agcccagaaa gctccgtgcg cacgaagctc atccagctcc cggtggtcta    180
cgtgatgctc atgcagcact cgctgtttct gccgactcta ctgacgtctg acggagagga    240
gagcccggac agccaagtaa aagaagcgct ggtggacctg atgctgacgg tggtggagat    300
gtgcccctct gtctgtgaga gcagccactt tgcagtgctt ctcgggggct atggngccan    360
tctcagcgtc ctagatcaga agatttactt ctgcttcgag cgtatgagca gaaaagtcag    420
cctcatcaat tcanggtgnt gct                                            443

<210> 195
<211> 481
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (394)
<223> n equals a,t,g, or c

<400> 195
ccagcggggc agcgcggggt cgccatggct gwgytgcagc agctccgggt gcaggaggcg     60
gtggagtcca tggtgaagag tctggaaaga gagaacatcc ggaagatgca ggtgagcggc    120
ccgaggccca gcagaggcgc tgccaacgtg aaagaccaga aaggcgagga cttccggcct    180
ccccgttggc caggtcatgc ctgcttctct tgcgcccaac ctcgcttcac acagcgcggg    240
tttctacact gttcttctct gagccccgca atgcctctgt gtgtttcggt cctgcttctc    300
tcacggagta tgcgtttccc agatagtgcc ccttgagtca ttgattagtg ggtcggctgc    360
cctctggtgg aattgtattg ctargttgct gacntctgga accccatggg aagaggctcc    420
gggtttttca gaatttgggt tcgtcagacc aacctaaccc tcaaccattg ggggggaaac    480
t                                                                    481

<210> 196
<211> 704
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (694)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (701)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (702)
<223> n equals a,t,g, or c

<400> 196
gcgtgacacg cacgcccagc ctggtttatt cataatcttt gtcttcctaa tgaaatgngg     60
aaactgactc tactctgtga tgccaagaca gatgggagtt tccttgtaca ccactttctc    120
tccttctatc tcaaagctaa ttgtaaagtc tgctttgtgg cactcatcca gtccttcagc    180
cactacagta tcgtgggaca gaagctgggt gtcagcctga ccatggcgcg ggagctgggg    240
cagcttgtgt tccttgaggg actcaagtct gcagtggacg tcgtcttcca ggctcaaaag    300
gagccacacc ccctgcagtt tctcagggag gctaatgctg ggaacttgaa accattgttt    360
gagtttgtac gggaggccct gaagccagta gacagtggag aggctcggtg gacgtacccg    420
gtgctgttgg tggacgacct cagtgtgytc ctgagcctgg gcatgggggc ggtggctgtg    480
ctagacttca ttcactactg cagagccacc gtgtgctggg aactaaaggg aaacatggtg    540
gtccttgtgc acgacagtgg aagatgcgga ggatgaggag aatgacatcc tgctgaatgg    600
cctcagtcat cagagccatc tgatactgcg ggctgaaggc ctgggccact ggtttctgca    660
aggaatttgc acggggaact gaggatcttt tggngagacc nntg                     704

<210> 197
<211> 767
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (270)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (660)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (691)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (735)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (737)
<223> n equals a,t,g, or c

<400> 197
gcgtccgcgc tgctggcgac atcacggctc cggaggtcky gtgcggccct caatgtcact     60
gtgtccccgg ggcccgtggt tgactacctg gagggggaga atgccactct cctctgccac    120
gtctcccata aaaggcggaa ggacagcttg ctggcgtgcg ctggttcttt gcacactcct    180
ycgactccca ggaggccttg atggtgaaga tgaccaagct ccgggtggtg cagtactatg    240
ggaatttcag ccgcagcgcc aaacggggan ggctgcgcct gctggaggag cagcgggggg    300
cgctctacag gctctccgtc ttgacactgc agccctccga tcaagggcat tacgtctgca    360
gagtccagga aatcagcagg cacaggaaca agtggacggc ctggtccaat ggctcctcag    420
ccacggaaat gagagtcatt tccctcaaag cttctgaaga gtcatccttt gagaaaacaa    480
aagagacttg ggcatttttt gaagatctct atgtgtatgc tgtcctcgtg tgctgcgtgg    540
ggatcctcac attctgctct tcatgctggt catcgtctgg cagtctgtgt ttaacaagcg    600
gaaatccaga gtgagacatt atttggtgaa atgccctcag aacagctcag gggagagctn    660
actagcgtga ccagcttggc cccactacak nccaagaagg gcaagaggca gaaggagaag    720
cctgacattc ctcgncnagt ccctgccaaa gctccgatag cccccac                  767

<210> 198
<211> 1322
<212> DNA
<213> Homo sapiens

<400> 198
agagagagag agagatcctc agagtggaag gagggggaag cagcaggaca cattggcaag     60
tcaagcagga aggagggaga tggaaagggg atatcagatt ggtttccccc ggtggagcct    120
taggttagtg cccagtgcag tgccagactg tctcctctgc tcctcccacc tcatccctag    180
gaggacccac cagtggagca catgcagcct cagtggagat gcttggtgtg gggatctggg    240
tgaagggggt tgagtagcga ctgcctggga gatggctgtt agtaggtctg ygcctggtgt    300
ctgcctcgcc atcctggggt aaggggcaga gagaaggact tgtcttatgt agggtgtggt    360
cagccttggg gccttaccta cccagttcca tgatatttct tgccctgttc cccctggaat    420
gtgcagtggg ccagctgaga gtacgccttg aggagggggg atgaggcctt aatctgggag    480
gcctatcccc ctatcccagg catcccagac gaggactggc tgaggctagg cgctctcatg    540
atccacctgc cccgggaggc agcggggaag acagagaaaa gcaaacgcat tcctcctcag    600
ctccacccac ctggagacga atgtagccag agaggaggaa ggagggaaac tgaagacacc    660
gtggcccctc ggcttctctc tgctagagtt gccgctcaga ggcttcagct gacttccagc    720
ggtcccaaga acacctacta attcctctgc actccttcat ggctgggaca gttactggtt    780
catatgcaag taaagatgac aatttactca acaaatattt atccgagcac cttttatgta    840
ccaggcactg ttgtaggtgc ttaggatatt ctcatgtttc tgagggatta cagcctggga    900
ggattccacc gatcttcact tctagcaggt tttttaaacg tgacccttgg ctgtatttcc    960
catcttcaca gttcaagcac cccaaacctg ccctttctcc cctgcagact ggcaggtggg   1020
attggctccc aggtcatttc ctctctctct ctttctccca agcctttctc cctccacagg   1080
aaacagattt ttcagggcct tccatgcctg ccactttgtc cgtctctttt ttttttttta   1140
aagtaatatt ttttagaaat acatgtaaaa taccaagaaa taatgtctgc gcctctgcca   1200
cctctctctc atctcttatt tcataaagct ggctctttat gttgctttac atgccttaat   1260
atatgtttta tggagattat acatattata gatctatata tgtaatatat ttgtttgggt   1320
gt                                                                  1322

<210> 199
<211> 610
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (593)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (594)
<223> n equals a,t,g, or c

<400> 199
ggacgntggg gnccgtcgcc ttcggagcga aggtaccgac ccggcagaag ctcggagctc     60
ttggggtatc gaggaggcag gcccgcgggc gcacgggcga ccgggccggg agccggagcg    120
gcggaggagc cggcagcagc ggcgcggcgg gctccaggcg aggcgggctc caggcgaggc    180
ggtcgacgct cctgaaaact tgcgcgcgcg ctcgcgccac tgcgcccgga gcgatgaaga    240
tggtcgcgcc ctggactcgg ttctactcca acagctgctg cttgtgctgc catgtccgca    300
ccggcaccat cctgctcggc gtctggtatc tgatcatcaa tgctgtggta ctgttgattt    360
tattgagtgc cctggctgat ccggatcagt ataacttttc aagttctgaa ctgggaggtg    420
amtttgagtt catggatgat gccaaaattc tttttaatct ttcggcagac atgtgcattg    480
ccattgcgat ttctcttctc atgatcctga tatgtgctag gctacttaag gagcgtacaa    540
gcaacgcgca cctgggatca tcccatcttc tgttaccaga tctttgaatt tgnnctgaac    600
atgttggttg                                                           610

<210> 200
<211> 531
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (398)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (460)
<223> n equals a,t,g, or c

<400> 200
aggacatcca ggcgcacctg gctcagggcc atgtggccat cgtgctggtg aactcggggg     60
tgctgcactg tgacctgtgc tccagccctg tcaagtactg ctgcttcacc cccagtggcc    120
accactgctt ctgccgcact cctgactacc agggccactt catcgtgctg cgtggctaca    180
accgggccac tggctgcatc ttctacaaca acccagccta tgccgamcga atgtgcagca    240
ccagcatcag taactttgar gaggccagaa ccagctwtgg cacagatgag gacatcctct    300
ttgtctactt ggacagctga cagcaggagc ctggtgcgcc taggccctcg gaccccatcc    360
ccaccccagc cgggcccgct caggacgccc tggcccangc ttggggctgc tggggttgga    420
atgtggaact gcagcctcag cccatctggc agaatcccan gaactcggaa actggcacag    480
ctgctttgtc tgccaatgcc gtgtgttgtc atgtcactca cccaagcacc t             531

<210> 201
<211> 576
<212> DNA
<213> Homo sapiens

<400> 201
agactttgga ttaacactgt acccactctt agcaaaaggg gacttctcta acaagctagc     60
attgtgttaa cctgtcatta acccagcatt agagacaggt cactgggatg ttcattctgg    120
ctctcagctg ctgttatttc cccactctca cctgtgctag ttcgctttct ccagaagagg    180
agctgaggtg gtcttatcct cagataggac atgagaaatt ggaatttggc aagcaagggc    240
ttcagcatcc tttagtttct aaagcaagat cccttcagag aagtctagca ggaagaagcc    300
aggagaatgt agaatggaaa agagctctta ctccaaattt tagagaagtt tcagctctac    360
ttctcatctt ttctctcctg gtcttacttg aatgcatgtt ggtaatctgt atacattact    420
atgactgtgt ctatcacaag tcctacaaaa taaaaatgga cttaaaagta ctctctgctg    480
aggctgtaag ttttgttttg tgagaaatag gtaaagacat tagcatttaa tctactggaa    540
taagctggtt gctgtggctt atacctgtag tccaga                              576

<210> 202
<211> 1321
<212> DNA
<213> Homo sapiens

<400> 202
ggcacgaggg tgaggcccag gtagcgtttg caatccagcc ccaccgtcac ctcttttctt     60
ggacttctag ttttcctcac ccctattgcc ttcatccttt tacctccgat cctgtggagg    120
gatgagctgg agccttgtgg cacaatttgt gaggggctct ttatctccat ggcattcaaa    180
ctcctcattc tgctcatagg gacctgggca ctttttttcc gcaagcggag agctgacatg    240
ccacgggtgt ttgtgtttcg tgcccttttg ttggtcctca tctttctctt tgtggtttcc    300
tattggcttt tttacggggt ccgcattttg gactctcggg accggaatta ccaagggatt    360
gtgcaatatg cagtctccct tgtggatgcc ctcctcttca tccattacct ggccatcgtc    420
ctgctggagc tcaggcagct gcagcccatg ttcacgctgc aggtggtccc gctccaccga    480
tggcgagtcc cgcttctaca gcctgggaca cctgagtatc cagcgagcag cattggtggt    540
cctagaaaat tactacaaag atttcaccat ctataaccca aacctcctaa cagcctccaa    600
attccgagca gccaagcata tggccgggct gaaagtctac aatgtagatg gccccagtaa    660
caatgccact ggccagtccc gggccatgat tgctgcagct gctcggcgca gggactcaag    720
ccacaacgag ttgtattatg aagaggccga acatgaacgg cgagtaaaga agcggaaagc    780
aaggctggtg gttgcagtgg aagaggcctt catccacatt cagcgtctcc aggctgagga    840
gcagcagaaa gccccagggg aggtgatgga ccctagggag gccgcccagg ccattttccc    900
ctccatggcc agggctctcc agaagtacct gcgcatcacc cggcagcaga actaccacag    960
catggagagc atcctgcagc acctggcctt ctgcatcacc aacggcatga cccccaaggc   1020
cttcctagaa cggtacctca gtgcgggccc caccctgcaa tatgacaagg accgctggct   1080
ctctacacag tggaggcttg tcagtgatga ggctttgact aatggattac gggatggaat   1140
tgtgttcgtc cttaagtgct tggacttcag cctcgtagtc aatgtgaaga aaattccatt   1200
catcatactc tctgaagagt tcatagaccc caaatctcac aaatttgtcc ttcgcttaca   1260
gtctgagaca tccgtttaaa agttctatat ttgtggcttt attaaaaaaa aaaaaaaaaa   1320
a                                                                   1321

<210> 203
<211> 904
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (836)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (858)
<223> n equals a,t,g, or c

<400> 203
cccacgcgtc cgcccacgcg tccgggccct agcagggcag gcgggaggtg agcgcggcca     60
tcccgctccc ggagttccgg atcctggagt ccgtagttcg tggtccttcg ccggtgtccc    120
cggagcccag cggctgtgga tggcagaagc ccagagtggg actggtcagc tgcaggagca    180
gaagaaaggt cttctgatag ccgtcagcgt ctccgttgat aaaatcatct cgcatttcgg    240
ggccgcccgg aacttggtgc agaaggccca gttgggtgat agccggctga gcccggatgt    300
ggggcacctg gtgctgacca ccctctgccc ggccctccac gccctggtgg cggacgggct    360
gaagcctttc cggaaggacc tcatcaccgg gcagcgcagg agcagcccct ggagcgtggt    420
ggaggcgtcg gtgaagccag gctccagcac ccgctccctt ggaaccctgt atagccaggt    480
cagccgtcta gccccgctga gcagcagccg tagccgcttc catgccttta tcctgggcct    540
cctcaacacc aagcagttgg agctgtggtt ttccagtctc caggaagatg caggcctgct    600
ctccctcctg tacctgccaa caggattttt ctccctggcc cgcggtggtt gtccctccct    660
gtccacagag ctgctgctcc tgctgcagcc attgtcggtg ctcactttcc acctggacct    720
gctctttgag caccaccacc acctgcccct gggcccacct caggcccctg cccctccagg    780
cccacctcca gctctgcagc agactatgca agccatgstg camtttgggg gccggntkgg    840
cmagagcctt ygggggantt ccaaggaagt tgyttcagac cctytgattt tcaaaacttc    900
ccat                                                                 904

<210> 204
<211> 1151
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1092)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1113)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1136)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1142)
<223> n equals a,t,g, or c

<400> 204
gagggaatgt ggaanccatt tttgaccacc agaacccttg tgccaacatg cagaggaaag     60
gcgtttttca gtaccatccc gatcggccat gctgtcaaag aagrgccagg cagaatcgtc    120
cttcccatam ttcacaaaag caacatagtg gcttgtttyt atgcagagaa cagcaaataa    180
ctccatattc tggcaaggga tgcagccgtg tctccagtcc cagtcgggta agtctttggg    240
aagtgacact gggttatatt tatgattcag cctcttcgga tgaaggtgga cttgagtgtt    300
gcaggtttta caaaactgct tgatttttcc agctgagatg tccggatcrt cgtagcattc    360
tctacactca tacattgcaa gccctccaca tatccggcac tgtctgggag tgtcttcaag    420
taaatctgtt atatttaatt ccagagaagg aaaaattttt ttaaatagtt taaagtcttt    480
tccaaatcga ggcatctgaa taatcagaca tgatggtgcc tctgcaaatt tcaggttact    540
gttgataaaa gaccattcta acaactgctg aattgtggga acgccaactt tctcattttt    600
ttccataaaa atttgataga agtaacaatc ttgtaccttt tgacctgctg atcttatttt    660
tagcaaaggt tctaccctta aaatatgatg aaacagaata ttcaagaatt cctcaggatc    720
tttttcttca gaggtaaatc ctgatgcagc ctccaccttt tcaagtattt tcctcagttt    780
cataattttt gtggcacaca catatccata tattctcaga ggattaacaa tttctgtcct    840
cagtagctct tgggtttcac tataatattc tacatcgttc ttttctttgg gtctaagtaa    900
cacagtgtcc agaacagaac taaaagcaaa taagcagaat aaggttgagt ctaagtaaca    960
agaattgtaa tgaccctgga tgcctttctt cttccccaat cattatctcc aagccttctt   1020
tttcccattt ttgggtggga gtattttcct ccactacttc acttaagtaa gcctcccaaa   1080
tggctaaaga gntacagcgg ctccaatctg gantggaacc gggctgcaat gatgcnaccc   1140
tngggtcagg c                                                        1151

<210> 205
<211> 1013
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (307)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (948)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (984)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1004)
<223> n equals a,t,g, or c

<400> 205
ggcanaggna ctcacaacca caatccaaat caaaaaatac atggtacatt gatgaagttg     60
cagaagaccc tgcaaaatct cttacagaga tatctacaga ctttgaccgt tcttcaccac    120
cactccagcc tcctcctgtg aactcactga ccaccgagaa cagattccac tctttaccat    180
tcagtctcac caagatgccc aataccaatg gaagtattgg ccacagtcca ctttctctgt    240
cagcccagtc tgtaatggaa gagctaaaca ctgcacccgt ccaagagagt ccacccttgg    300
ccatgcntcc tgggaactca catggtctag aagtgggctc attggctgaa gttaaggaga    360
accctccttt ctatggggta atccgttgga tcggtcagcc accaggactg aatgaagtgc    420
tcgctggact ggaactggaa gatgagtgtg caggctgtac ggatggaacc ttcagaggca    480
ctcggtattt cacctgtgcc ctgaagaarg cgctgtttgt gaaactgaag agctgcaggc    540
ctgactctag gtttgcatca ttgcagccgg tttccaatca gattgagcgc tgtaactctt    600
tagcatttgg aggctactta agtgaagtag tagaagaaaa tactccacca aaaatggaaa    660
aagaaggctt ggagataatg attgggaaga agaaaggcat ccagggtcat tacaattctt    720
gttacttaga ctcaacctta ttctgcttat ttscttttag ttctgttctr gacactgtgt    780
tacttagacc caaagaaaag aacgatgtag aatattatag tgaaacccaa gagctactga    840
ggacagaaat tgttaatcct ctgagaatta atkgatactg ggaacaagac aggtcaaacc    900
cgaaactcta aggcatgtta acacctcctt cctagaagag aggaaganta aacattcttt    960
gggatcctat tgttcagcca gttnaagatc atagttaatc acanttccta acc          1013

<210> 206
<211> 557
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (512)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (528)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (534)
<223> n equals a,t,g, or c

<400> 206
ggcagagttt ttactcaacc tctttgatga cacagcaaaa acagacgtga ctatgctctt     60
gtatatagca gacaatctag cctgttttcc ataccagaca caggaagagc cgttgtttat    120
aatgcatcat atagacatta cactctcagt ttctggtagt aacctactgc agtcattcaa    180
ggagtctatg gtaaaggaca aaaggaaaga gagaaaatca tcacctagta aggaaaatga    240
gtcaagcgac agtgaagaag aagtttccag gcctcggaag tcacggaaac gtgtagattc    300
agattcagat tcagattcag aagacgrtat aaattcagtg atgaaatgtt tgccagaaaa    360
ttcagctcct ttaatcgaat ttgcaaatgt gtcccagggt attttattac ttctcatgtt    420
aaaacaacat ttgaagaatc tttgtggatt ttctgatagt aaaattcaga agtactctcc    480
atctgaatct gcaaaagtat atgataaagc gntaaccgaa aaccaggngt ccantttcat    540
cccaaaccaa acactgg                                                   557

<210> 207
<211> 729
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (42)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (48)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (729)
<223> n equals a,t,g, or c

<400> 207
aagagatttc agntaacaac tggagaaagg atcagagcca ancaagantc ccaagttaag     60
aaggcaactt aggagacttt tgtaatcytc tgaatgagag ttgacaatag cccaaacgag    120
ggtactggca gtaggggaag tagagaagtg gaaagatttg cgagytytct gcaaggtata    180
cctggcagga tttgggaatg actgtgggag gcaggggcag gaggtattaa gaatgatgcc    240
agaacaccag taggatgggg gttccattta ccaagatagg caatatggga gaaggaacat    300
gtctggaagg gaacataact catttttgct gagttttggg gatctgggat atataaactg    360
agatatccac acatctgaag ctcaagagaa gagrtcggat tggcagttat aaatctgaga    420
cttgctggca tataaatggt tatcatagct gtggaagtag atgaggtcat tcggcaagag    480
tgcgttcaac aacttcaaga gaagcagccc agtgacagaa ccatgagaat tatcagcaga    540
gacaggtggc ggcaaggctg caaaggtcca cagaaaggta ggaccagaga ggaagaaagc    600
aaacgaggca aatgtagaga agcacatcag cccactgctc tctcttccca ctcttaccca    660
ccagtccatc ttgccaccac ttctttcttg gatgctgctc cagcctccta atcgctccct    720
atatccntn                                                            729

<210> 208
<211> 435
<212> DNA
<213> Homo sapiens

<400> 208
gaccacttgg gggactgatt gcagggttgt gggaagtcct gagtggaagt tggttacggg     60
gtaggagagg ggtcctgagt ggaaggaagc tggtcagagt gggacggatg gactgaatgg    120
aaattggaat agggagtgag gcggagtttt acgcaagggt accgtatcca gttttgggct    180
ggaggatagt tgcaagtatt gtttggtcag tgctatttct acccatctgc accacagtat    240
ttataatttt cagcaggatt gattwgtttc atcctataca gtggctgtct gattctttca    300
gtgacctgta tagttcctat gtaatctttt acttcctgct gctgtcagtg gtaataataa    360
taataagtat tttcaatgtg gagttctatg cagttgtgcc ttctattyct tgctycagac    420
tarctctgat aggga                                                     435

<210> 209
<211> 2808
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1164)
<223> n equals a,t,g, or c

<400> 209
gatgatggtg gaaaacatca tgaacaagga agccttcatg aaccaggaga ttacgaaagc     60
ctttcacgta aggaaagcca atcggataaa agagtgtctc agcaagggaa cgttctcgga    120
cgtgacattt aaattggacg atggagccat cagtgcccac aagccgctgc tgatctgtag    180
ctgtgagtgg atggcagcca tgttcggggg gtcatttgtg gaaagtgcca acagtgaggt    240
gtatctcccg aacataaaca agatatcaat gcaagcagta ttggattatc tctataccaa    300
gcagttgtct cctaacttgg atctggaccc gctggaatta attgccttgg caaacagatt    360
ttgcctgcca cacttggttg cacttgcaga acagcatgcc gttcaggagt tgaccaaagc    420
cgccacgagt ggcgtgggca ttgacggaga agtgctctct tacttggaat tggctcagtt    480
tcacaatgcc caccagttgg ccgcctggtg tttgcaccac atctgcacca actacaacag    540
tgtatgctcc aagttccgta aggaaatcaa atcaaaatct gcagacaacc aggaatactt    600
cgagcggcac cgctggcccc ctgtgtggta cctgaaggaa gaagatcact accagcgtgt    660
gaaaagggaa cgagagaagg aagatattgc actaaataag catcgctcaa gacgaaagtg    720
gtgcttctgg aattcatctc cagcagtggc ctgaagagga agagaaaaaa aaacaaaaaa    780
cagaaaccaa tcggyaatct gatccaccac ttttcaaagc actactataa aattcgtctt    840
gktagagata cgacatagtt cargtttcgg gcactgatct tcctccactt ttgtgcattt    900
atctttgtta ggatcaaagc acaagctcac catcaatgag cctggacaaa aagggaagct    960
gactctcact gcattcctta aactgatatg tatatttttt ttgttaggag gcttaataaa   1020
ctttagtctg ttattttgtt tctttttata caaagaaaaa aaattcagct ttcatgtttc   1080
tgattccaga ttggaaaata tttttatatg gtctgttgta ttttgttgaa atgaaaatac   1140
tgtgtattac tttattttac aggnccacaa ttgattatga agtcaccctg tgattctctt   1200
tgscccacat gaccaccgag cattattacg taattagagg gttatccttt tgytgtgaaa   1260
ggaaggaggg gactgaaatc tcccaaagtg caaattggag agtgtttaat ctttgttctg   1320
ttgaataaca tcggtgtaat tacaaagtca actccaagaa tgtgtattta caatatttgc   1380
catgttaagt gctggtaatt atatggttat atgtgccatg taaaatatag tgatatcaaa   1440
tattctgttg tttccaatgt ctagtttcaa gaggacaatc tttataatca ttagaagggc   1500
ttattaaatc ccagcattat ccagggcaaa ctcactggtg gacctgaata cataagatac   1560
cattagtgcg ctggtgttcg gattgctgta ttagggttta catctctcag tattccttga   1620
acttgccatg cttctgcatg cagattcttc actgacttga attgagatgg gcaagggaaa   1680
aggtccctgg actccctcct gccatctaca ggcttgtcac atctcaccac cagaaacagg   1740
cttcctcagg cttctcacct gtggccaact tcactttgta agacccatat ttttaactct   1800
tcccrgggaa aattcatgtt gctgcagaag taggstaagg cagaccaccc acttctgctg   1860
aaatgcattg ggagcctgtg aaagcacaaa gctggaggct gggcgcctgc kttctcctac   1920
acggaaagga atctaattcc aagagtctag gaaatggtgc tattgtgagt tcgttctgac   1980
tctttctcat tctgagtttt cagtgttaaa ctaggaagtg tgacagcagg ggagctttcg   2040
tgaggcagtc agtcattgct tctctgtaaa ttaaaatgtt acagcacaca catacacaca   2100
cagagagcat ttcaaggcca cagctccaca cctgccatgg gatgttaatg tggcaggggg   2160
tggggctcat tctgttggga ggtcaaatta ccaatgccaa ggactgttga ttttgttttt   2220
atttttattt tttcttctag cttttcagaa gatggaaatg agacagttga gtccaaaccc   2280
caatgctgac agccatatgc atttgaaaat ctatctagat tacagatggg catttattac   2340
tggcagtgga aacaccagat agaagatctt aggagaggcc cagaaatgca tcaccttgtc   2400
atgacaaaag agaaggcagt agagtaggga tagttacaaa tgcatccatc ttaattattt   2460
tcaataggct tgtaaatctt atcgatggaa ggagaaagga gacaagatgt ggaagaattg   2520
acatgtatcc caccataaaa tggtagaaga tgagttttca atgagtagtc atagttgaaa   2580
ttttacaacc aaagctccca tttgattgta atcttgccaa aatataatgg atgtataaat   2640
gaacttgggg tataagcaat aatatccact agtgttgtta tcagctactg taaccaagtg   2700
gctggttcat ttggttgatg ctgattatgg cctttaacca tggtggtttg ttgtgtgttt   2760
tttatttcac aaaaagccaa taaaattgtt tagctataaa aaaaaaaa                2808

<210> 210
<211> 842
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (824)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (827)
<223> n equals a,t,g, or c

<400> 210
aaatttgcca agccaagagt taccccagga agattctctc ttacatggcc aattttcaca     60
agcagtcact cccctagccc atcatcacac agattattca wagcccaccg atatctcatg    120
gagagacaca ctttctcaga agtttggatc ctcagatcac ytggagaaac tatttaagat    180
ggatgaagca agtgcccagc tccttgctta taaggaaaaa ggscattctc agagttcaca    240
attttcctct gatcaagaaa tagctcatct gctgcctgaa aatgtgagtg cgctcccagc    300
tacggtggca gttgcttctc cacataccac ctcggctact ccaaagcccg ccacccttct    360
acccaccaat gcttcagtga caccttctgg gayttcccag ccacagctgg ccaccacagc    420
tccacctgta accaytgtca cttytcagcy tcccacgacc ctcatttcta cagtttttac    480
acggggctgc ggctacactc caagcaatgg ctacaacaga gttctgacta ccacctttca    540
ggcacctacg gactcgaaag gcagcttaga aaccataccg tttacagaaa tctccaacyt    600
aactttgaac acagggaatg tgtataaccc tactgcactt tctatgtcaa atgtggagtc    660
ttccactatg aataaaactg cttcctggga aggtagggag gccagtccag gcagttcctc    720
ccagggcagt gttccagaaa atcagtacgg ccttccattt gaaaaatggc ttcttatcgg    780
gtccctgctc tttggtgtcc tgttcctggt gataggtctc gtgnctnctg ggtaggattc    840
ct                                                                   842

<210> 211
<211> 1612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1612)
<223> n equals a,t,g, or c

<400> 211
gaggggaacc tcaggcttca gagagccgaa aagttgggag gcgtaaccac ttacaggccg     60
gaagtgtccg gggtggacgc attcgggtag ccgaagaagt cccaggattg ccgaagaagt    120
cccaggattt ccgaagcgag ccgaagcatc gcgacagttt tcagagacag ctgatcggtt    180
ggagctsttg cgccgagcag tcatggcggc ggccagagct actacgccgg ccgatggcga    240
ggagcccgcc ccggaggctg aggctctggc cgcagcccgg gagcggagca gccgcttctt    300
gagcggcctg gagctggtga agcagggtgc cgaggcgcgc gtgttccgtg gccgcttcca    360
gggccgcgcg gcggtgatca agcaccgctt ccccaagggc taccggcacc cggcgctgga    420
ggcgcggctt ggcagacggc ggacggtgca ggaggcccgg gcgctcctcc gctgtcgccg    480
cgctggaata tctgccccag ttgtcttttt tgtggactat gcttccaact gcttatatat    540
ggaagaaatt gaaggctcag tgactgttcg agattatatt cagtccacta tggagactga    600
aaaaactccc cagggtctct ccaacttagc caagacaatt gggcaggttt tggctcgaat    660
gcacgatgaa gacctcattc atggtgatct caccacctcc aacatgctcc tgaaaccccc    720
cctggaacag ctgaacattg tgctcataga ctttgggctg agtttcattt cagcacttcc    780
agaggataag ggagtagacc tctatgtcct ggagaaggcc ttcctcagta cccatcccaa    840
cactgaaact gtgtttgaag cctttctgaa gagctactcc acctcctcca aaaaggccag    900
gccagtgcta aaaaaattag atgaagtgcg cctgagagga agaaagaggt ccatggttgg    960
gtagaagaat gtgtatgaca accacacaca gtgaagctct tttttcaaag taaatttgaa   1020
gaaatgctac aagtatgaga tgagatctaa gtaaaggtgt taagatattt ttaagtggta   1080
tgtgatcgtg tcattatcat ctgcacttca ctcaagagct tactatgtgt ctaagtcatg   1140
ttctaggcag aattgggtat ttaaagtaaa ttgaggacag gcttctccca gattgtgaca   1200
tgtatatctc agatacatgg gtgtggcatt gaaccacata atgagaacat tattctcttt   1260
ttagtccttg tgagacaagg atgaagtctc agttgctgat actcgctgag cttactggcc   1320
ctcgtaaccc agtgtttttt tttgttgttg ttgtgtacat gttatattta ttttgaaacc   1380
agtttaatgg gatacaacca gcattttaaa aaatgaaata gaatacagca tggaaaatat   1440
cagtgtattg ttttatgaaa ctttcatgtg tatatataga ccaaggatat gtgctgagtt   1500
ttgatgtcaa atatatttct ctttcagggt catgatcaaa aaatgaaaag tctgcttaac   1560
tccaattyct ctttaaaaaa gcagacttac agctttcagg caactgaaat cn           1612

<210> 212
<211> 540
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (516)
<223> n equals a,t,g, or c

<400> 212
ggcttgggaa aacagaatgg ccctagacat gatattagcc aaaaaaggtg gagtttgtgt     60
tatgatcaaa actcaatgtt gtaccttcat cccaaacaat actgccccta gtgggagcat    120
aacaagggcc ttacaaggcc ttactgcttt atccaatgaa ttagctaaaa attctggagt    180
caatgaccct ttttcaggat ggctagaaag gtggtttggt aaatggaaag gaatcatagc    240
ctcaattctt acttctcttg cagccgtaat aggtgtagtc attctttttg ggtgttgtgt    300
cacaccatgt atccgtgggc tagtacagag gcttatagaa acagtactta ctaaaacctc    360
ccttagctct cctccacctt attcagataa gcttttcctt ttagaggatc aagtcgaaca    420
gcaaagccaa gacttgttaa aaaggtttga agaggaagga ccataacaat tgaaaggggg    480
aaattataag atacagtaaa ttcctcttca aagatntagc ctgttgactt ccttattctt    540

<210> 213
<211> 803
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (90)
<223> n equals a,t,g, or c

<400> 213
ggcctctgga atcacccggg tcgctgttcc tgaggtggtc aaggtggaca gggggcggtg     60
gtgatggcgc agtttgacac tgaataccan cgcctagagg cctcctatag tgattcaccc    120
ccaggggagg aggacctgtt ggtgcacgtc gccgagggga gcaagtcacc ttggcaccat    180
attgaaaacc ttgacctctt cttctctcga gtttataatc tgcaccagaa gaatggcttc    240
acatgtatgc tcatcgggga gatctttgct accttcctgg tcagctgcgt ggactatgac    300
atcctatttg ccaacaagat ggtgaaccac agtcttcacc ctactgaacc cgtcaaggtc    360
actctgccag acgccttttt gcctgctcaa gtctgtagtg ccaggattca ggaaaatggc    420
tcccttatca ccatcctggt cattgctggt gtcttstgat ccaccggctt atcaagttca    480
tctataacat ttgctgctac tgggagatcc actccttyta cctgcacgct ctggcatccc    540
tatgtctgcc cttccgtatt gcacgtggca agaagtgcag gcccggatcg tgcagacgca    600
gaaggagcac cagatctgca tccacaaacg tgagctgaca gaactgggac atctaccacc    660
gcatcctccg tttccagaac tacatggtgg cactggttaa caaatccctc ctgcctctgc    720
gsttccgcct gcctggcctc ggggaagctg tcttcttcam ccgtggtctc aagtacaact    780
ttgagctgat cctcttctgg gga                                            803

<210> 214
<211> 460
<212> DNA
<213> Homo sapiens

<400> 214
ggcacgagcc tgagcgggcc ggggccatga gcgccgcccg gccccagttc agcattgatg     60
atgccttcga gctgtccctg gaggacgggg gccctgggcc cgagtccagc ggggtcgcgc    120
gctttgggcc gctgcacttc gagcgtcggg cccggttcga ggtggctgac gaggacaagc    180
agtcccggct gcgctaccag aacctggaga acgatgagga tggagcccag gcctctccgg    240
agccggatgg gggagtcggc accagctccc agtggtcctt cagcaccatc agcagcagca    300
cccagcgctc ctacaacamc tgctgcagct ggacccaaca mcctttgatc cagaagaacc    360
gccgagtggt gctggcctcc ttcctgctcc tgctgctggg gytggtgctg atctggtcgg    420
cgttggactt gaagcgaccc cctctccagg tgtctccagg                          460

<210> 215
<211> 1659
<212> DNA
<213> Homo sapiens

<400> 215
ggcagagccg tgctggggac tggacgtccg ctggctgctg cgcacgcaaa acctctcgct     60
tccctgtacc aggtcctcgc ggaggaaggg gagggacgag gcgcggcttt tcctgtgccg    120
cctgcccggt tcgacctgcg cggcctgcgg cttcttggga actctagggc cgcggccggg    180
cctggctctg ccggcggcct gttgggagct ggatcggagc ggtttggaac gacaagcccg    240
acaaagagac ttttaaaaaa ccatggcaga tgtggaccca gatacattgc tggaatggct    300
acagatggga cacggagatg aaaggacatg caactaatag cccttgaaca gctatgcatg    360
ctgcttttga tgtctgacaa cgtggatcgt tgttttgaaa catgtcctcc tcgcactttc    420
ttaccagccc tttgcaaaat ttttcttgat gaaagtgctc cagacaatgt attagaggtg    480
acagcccgtg ccataacata ctacctggat gtatctgcgg aatgtacccg aaggattgtt    540
ggggtagatg gagctataaa agcactttgt aatcgtttgg ttgtagttga acttaacaac    600
aggactagca gagacttagc tgaacagtgt gtaaaggtat tagaactgat atgtactcgt    660
gagtcaggag cagtctttga ggctggtggt ttgaattgtg tgcttacctt cattcgtgac    720
agtggacatc tagttcataa agacaccttg cactctgcta tggctgtggt atcaagactc    780
tgtggcaaaa tggagcctca agattcttct ttagaaattt gtgtagaatc tctgtctagt    840
ttatgaaagc atgaagatca tcaggtttca gatggagctc tgcgatgctt tgcatcactg    900
gctgaccgat ttacccgtcg tggtgttgac ccagctccat tagccaagca tggattaact    960
gaggagctgt tatctcgaat ggctgctgct ggtggtactg tttcaggacc atcatcagca   1020
tgcaaaccag ttcgcagcac cacaggagct ccatccacca ctgcagattc caaattgagt   1080
aatcaggtgt caacaattgt aagtctgctc tcaacacttt gcagaggctc tccggtagta   1140
acacatgatc ttctgaggtc ggagcttcca gattcaattg aaagtgcatt gcagggtgat   1200
gaaagatgtg tgcttgatac tatgcgtttg gttgactttc tcttggtgct attatttgaa   1260
ggacgaaaag ctttgccaaa gtctagtgct ggatctacag gcagaatccc aggactccgg   1320
agattagata gttctgggga gcgctcacat cggcagctta tagattgtat tcgaagtaaa   1380
gataccgatg cacttataga tgcaattgac acaggagcct ttgaagtaaa ttttatggat   1440
gatgtaggtc agactctatt aaactgggcc tctgcttttg gaactcagga aatggtagaa   1500
tttctttgtg agagaggtgc agatgttaat agaggtcaaa gtcatcatca ttacattatg   1560
ctgcatgttt tggaagacct caagtagcaa agactctgtt acggcatggt gcaaatccag   1620
atctgagaga tgaagatggg aaaactccat tagataaag                          1659

<210> 216
<211> 1147
<212> DNA
<213> Homo sapiens

<400> 216
ggcacgagct aggagcctcc taatgcagtc ttctgcacag tcctggggac tgactgactg     60
aatcacacct ctggggctgg gggctgctga catgtgtgcc tttccttggc tgcttcttct    120
cctgctgctc caggagggca gccaaaggag actctggaga tggtgtggat ccgaggaagt    180
ggttgcggtc cttcaggagt ccatcagcct ccccctggaa ataccaccag atgaagaggt    240
tgagaacatc atctggtcct ctcacaaaag tcttgccact gtggtgccag ggaaagaggg    300
acatccagct accatcatgg tgaccaatcc acactaccag ggccaagtga gcttcctgga    360
ccccagctat tccctgcata tcagcaatct gagctgggag gattcagggc ttttaccaag    420
ctcaagtcaa cctgagaaca tcccagatct ctaccatgca gcagtacaat ctatgtgtct    480
accgatggct gtcagagccc cagatcactg tgaactttga gagttctggg gaaggtgcct    540
gcagtatgtc cctggtgtgc tctgtggaga aggcaggcat ggatatgacc tacagctggc    600
tctcccgggg ggatagcact tatacattcc atgaaggccc tgtcctcagc acatcctgga    660
ggccggggga cagtgccctc tcctacacct gcagagccaa caaccccatc agcaacgtca    720
gttcttgccc catccctgat gggcccttct atgcagatcc taactatgct tctgagaagc    780
cttcaacagc cttctgcctc ctggccaagg gattgctcat cttcttgctc ttggtaattc    840
tggccatggg actctgggtc atccgagtcc agaaaagaca caaaatgcca aggatgaaga    900
aactcatgag aaacagaatg aaattgagga aggaggcaaa gcctggctcc agccctgcct    960
gactgctcct tgggaacccc agtcctgagc ttggtttctt cccagcaccc agagaatcct   1020
tcctcagctc tcttctttcc aggggaagga ggtgctcagg ggtgggtatc cagagagcca   1080
tacttctgag ggaagactgg ctggcaataa agtcaaatta agtgaccacc aaaaaaaaaa   1140
aaaaaaa                                                             1147

<210> 217
<211> 319
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (312)
<223> n equals a,t,g, or c

<400> 217
agatccccat gcctcgagcc ctggatctcc aagctcagct gctggattct ggatgtcaac     60
aaacctcacc actggatcct gacaaccaca atgcctggat cctggggccc ccatcactgg    120
atcccagatc ccctcactcc acccactgga ttcctgcatt ggtttttggt tttttgtttt    180
tttttaacct ckacactggg tctcaakatc cttctgctga mtgccaagat ccctgcattt    240
caagcactac gccttccaac cccaaggcac tggaatccag atttccaaag cctttaccaa    300
caagattctg gntcctaaa                                                 319

<210> 218
<211> 500
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (213)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (409)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (433)
<223> n equals a,t,g, or c

<400> 218
ggaaggtgcc cagctgaact ttgattattt cctatgcagc ataaagttct gctcctcggg     60
agtaaatctg caaatcagag ccttcctcag gaagatagct ctacagatga cccaggggaa    120
caagtacaag ccgtgcgttc cagcacccag gatttcttgy ttcatgtcat tttaaagaac    180
acatggtttc gagtatacta tggagtccta ggnttattcc cagccttggc ctcagttgtc    240
aagctagctg ttccttttta cttgggggat tcagcccctt cccattttac ccaccaactc    300
ttaatcatct cccctgctct actcaaccat ctttttctgg acactcttcc tgcttcctgc    360
ataacctagt ttagagcart ccccttatgc tagtctctaa agcttctgnt cttatcacaa    420
ttttaatcaa agnatactct ctctcttttt ttttttcttc ctgagatgga gcctcactct    480
gttgccaggg ctaaaatgca                                                500

<210> 219
<211> 1391
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (721)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1384)
<223> n equals a,t,g, or c

<400> 219
attccagaaa agagtactgg aatacttggc tgtcagacag ctcaaaaata acctgaaggg     60
cccaatccta tgctttgttg gccctcctgg agttggtaaa acaagtgtgg gaagatcagt    120
ggccaagact ctaggtcgag agttccacag gattgcactt ggaggagtat gtgatcagtc    180
tgacattcga ggacacaggc gcacctatgt tggcagcatg cctggtcgca tcatcaacgg    240
cttgaagact gtgggagtga acaacccagt gttcctatta gatgaggttg acaaactggg    300
aaaaagtcta cagggtgatc cagcagcagc tctgcttgag gtgttggatc ctgaacaaaa    360
ccataacttc acagatcatt atctaaatgt ggcctttgac ctttctcaag ttctttttat    420
agctactgcc aacaccactg ctaccattcc agctgccttg ttggacagaa tggagatcat    480
tcaggttcca ggttatacac aggaggagaa gatagagatt gcccataggc acttgatccc    540
caagcagctg gaacaacatg ggctgactcc acagcagatt cagatacccc aggtcaccac    600
tcttgacatc atcaccaggt ataccagaga ggcaggggtt cgttctctgg atagaaaact    660
tggggccatt tgccgagctg tggccgtgaa ggtggcagaa ggacagcata aggaagccaa    720
nttggaccgt tctgatgtga ctgagagaga aggttgcaga gaacacatct tagaagatga    780
aaaacctgaa tctakcagtg acactactga cttggctcta ccacctgaaa tgccgatttt    840
gattgatttc catgctctga aagacatcct tgggcccccg atgtatgaaa tggaggtatc    900
tcagcgtttg agtcagccag gagtagcaat aggtttggct tggactccct taggtggaga    960
aatcatgttc gtggaggcga gtcgaatgga tggcgagggc cagttaactc tgaccggcca   1020
gctcggggac gtgatgaagg agtccgccca cctcgctatc agctggctcc gcagcaacgc   1080
aaagaagtac cagctgacca atgcttttgg aagttttgat cttcttgaca acacagacat   1140
ccatctgcac ttcccagctg gagctgtcac aaaagatgga ccatctgctg gagttaccat   1200
agtaacctgt ctcgcctcac tttttagtgg gcggctggta cgttcagatg tagccatgac   1260
tggagaaatt acactgagag gtcttgttct tccagtgggt ggaattaaag acaaagtgct   1320
ggcggcacac agagcgggac tgaagcaagt cattattcct cggagaaatg aaaaagacct   1380
tgangggatc c                                                        1391

<210> 220
<211> 1140
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1039)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1070)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1091)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1120)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1136)
<223> n equals a,t,g, or c

<400> 220
gcaccgtgga gctgcaggag atgccccttg tccaggagtt gccactgctg aagcttgggg     60
tgaattacct tccgtccatc ttcatcgctg gggtcaattt tgtgctgccg ccsgtgtttc    120
aagctcattg ctccactgga gggctacact cggagtcgcc agatcgtttt tatcctgctc    180
aggaccgtgt ttcttcgcct cgcctccctg gtggtcctgc tcttctctct ctggaatcag    240
atcacttgtg ggggcgactc cgaggctgag gactgcaaaa cctgtggcta caattacaaa    300
caacttccgt gctgggagac tgtcctgggc caggaaatgt acaaacttct gctctttgat    360
ctgctgactg tcttggcagt cgcgctgmtc atccagtttc ctagaaagct cctctgtggc    420
ctctgtcctg gggcgytggg tcgtctggcg gggacccagg agttccaggt gcccgacgag    480
gtgctggggc tcatctacgc gcagacggtg gtctgggtgg ggagtttttt ctgcccttta    540
ctgcccctgc ttaacacggt caagttcctg ctgcttttct acctgaagaa gcttaccctc    600
ttctccacct gctccccggc tgcccgcacc ttccgggcct ccgcggcgaa tttctttttc    660
cccttggtcc ttctcctggg tctggccatc tccagcgttc ccctgcttta cagcatctyc    720
ctgatcccgc cttctaagct ttgtggtcca ttccgggggc agtcgtccat ctgggcccag    780
atccctgagt ctatttccag cctccctgag accacccaga atttcctctt cttcctgggg    840
acccaggctt ttgctgtgcc ccttctgctg atctccagca tcctgatggc gtacactgtg    900
gctctggcta actcctacgg acgcctcatc tctgagstca aacgtcagag acagacggag    960
gcgcagaata aagtcttcct ggcacggcgc gctgtggcgc ttamcctcca ccaaaccsgg   1020
ytytttgamc ccccgcaanc ccacgttccc ggcttttcaa gaacccccan ggcccattgg   1080
taagccctaa nggtcaacaa acattctggt aaaacttaan ggaagaacct gggagnaaat   1140

<210> 221
<211> 801
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (796)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (799)
<223> n equals a,t,g, or c

<400> 221
ccctcacttc tgtgccacca atgaatccag ctactacatt accaggtctg atgcctttac     60
cagcaggact gcccaacctc cccaacctca acctcaacct cccagcacca cacatcatgc    120
caggggttgg cttaccagaa cttgtaaacc caggtctgcc acctcttcct tccatgcctc    180
cccgaaactt acctggcatt gcaccaccgt tgaggacaga gtcggcgact ccaccccagt    240
cagcgagaag cctgtttctg cggctgtgga tgccaatgct tctgagtcac cttaactttg    300
aaccattctt tggaattggc gtggtatatt taaccacggg agcgtgtctg gaaacgcaaa    360
ctatcattaa tttcatacta gtttgtaccg tatctgtagg catcctgtaa ataattccaa    420
ggggaaaact aaacgaggac gtgggttgta tcctgccagg ttgagtgggg ctcacacgct    480
agggtgagat gtcagaaagt gcttgtattt taaacaacca aaaagaattg taagggtggc    540
ttgctgccag gcttgcactg ccgttcctgg gggtgtgcat cttcgggaaa ggtggtggcg    600
gggcgtccac taggtttcct gtcccctgct gctccttccg taagaaaatg aaatattcta    660
tgcctaatac tcacacgcaa catttcttgt actttgtaag tcgtttgcga gaatgcagac    720
cacctcacta aactgtaaac ggtaaagaga tttttacttt tggtcaaaaa aaaaaaaaaa    780
aaaaaagggg gggccnccnt a                                              801

<210> 222
<211> 715
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (651)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (692)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (708)
<223> n equals a,t,g, or c

<400> 222
ctagccccca gcatgtgtgt caccttctgc ccatctccag gcactccagg ggtcagggct     60
ttgtgagctc ttttccctat ctatgaagta ggcaggatgt ggtctgcctg gcccagcact    120
cagggtgttc ctcagtgact gggggctctg tcaagcacca gcaagggtct acgagacagc    180
agcaggacaa atgaccactg tatgcacagt caagagaaca tatagaaaca taaatgaatg    240
aacaaatgat gaacataggc aatgaggagc aaggccctga tagctcatcc tggggtgata    300
actacttggg ctattctctg ggcttaggga gcagaagggc ctggagtccc tacggcctgt    360
gcctctcaca gccttctctc tccttcttgc aggaaaccag ccatgtcctt tgggctctgt    420
ggagagcttt agccttgcac sgcggcgctg ggaggcattg cctgccatgc ccactgcccg    480
ctgctcctgc tctagtctgc aggctgggcc ccggctgttt gttattgggg gtgtggccca    540
gggccccagt caagccgtgg aggcactgtg tctgcgtgat ggggtctgaa ggcttggtgg    600
gagtgtccac tggagcagct cattgccaga gcagctattt tctatggntc ntttggtgct    660
gaggacattc atgtggctct gtgggatgag anagcagggg gtgagcantg aaaca         715

<210> 223
<211> 808
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (724)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (770)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (807)
<223> n equals a,t,g, or c

<400> 223
gggcannagt cgtcccttca gcggggcgct gcagctgacg gacctggatg acttcatcgg     60
gccgtctcag gagtgcatca agcctgtcaa agtggaaaaa agggcgggaa gtggcgtggc    120
caagattcgc attgaagatg acgggagcta cttccaaatt aaccaagacg gcgggacccg    180
gaggctggag aaggccaagg tctcgctaaa cgactgcctg gcgtgcagcg gctgcatcac    240
ctccgcagag accgtgctta tcacccagca gagccacgag gagctgaaga aggttctaga    300
tgctaacaag atggcggcac ccagtcagca gaggctggtt gtagkttcgg tctcaccaca    360
gtctagagca tcgctggctg cacggtttca gctgaatcct acagatactg ccaggaaatt    420
aacctcattc tttaaaaaaa taggggtgca cttcgtcttc gacaccgcct tctcaaggca    480
cttcagcctc ctggagagcc agcgagagtt tgtgcggcga ttccgaggac aggccgactg    540
cagacaggcg ctgcccctgc tggcctctgc ctgcccaggt gtgctcatgg tgcgggtggt    600
gggagagtca agttcaagtg cagttgaaac gtgaggtgat atggacacaa atgacaaggc    660
gggggcatgg ggggtggaga cgcaagcagg ttttgcgggg acgggttgga aatgttggca    720
caantgggct ttttctggag aagaggctgc ccttcccgtg ggagccacgn gcattcaact    780
caggtcccta ggcgttgtcg cctgcang                                       808

<210> 224
<211> 893
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (813)
<223> n equals a,t,g, or c

<400> 224
ctgcgcgccg gggccgcctc tccttccgcc ggtgccgcgg cgcctcatgg aagccccgga     60
gggcggcgga ggggggcctg cagcgcgggg cccggarggc agccggcgcc cgaagccagg    120
gtgcacttcc gagtggcgag gttcatcatg gaggcaggtg tcaagctagg gatgcggtcc    180
attcccattg ccactgcttg caccatttac cataagttct tttgcgagac caacctggac    240
gcctatgacc cttacctgat tgccatgtct tcaatttact tggccggcaa agtggaagag    300
cagcacctgc ggactcgtga catcatcaat gtgtccaaca ggtactttaa cccaagcggt    360
gagcccctgg aattggactc ccgcttctgg gaactccggg acagcatcgt gcagtgtgag    420
cttctcatgc tgagagttct gcgcttccag gtctccttcc agcatccaca caagtacctg    480
ctccactacc tggtttccct ccaraactgg ctgaaccgcc acagctggca gcggacccct    540
gttgccgtca ccgcctgggc cctgctgcgg gacagctacc atggggcgct gtgcctccgy    600
ttccaggccc agcacatcgc cgtggcggtg ctctacctgg ccctgcaggt ctacggagtt    660
gaggtgcccg ccgaggtcga ggctgagaag ccgttgggtg gcaggtgttt aatgacgacc    720
ttaccaagcc aatcattgat aatattgtgt ctgatctcat tcagatttat accatggaca    780
cagagatccc ctaaggtcct ggcccagggc tgnccaaaga gaagcccagg atggtcggct    840
gcctggggac attgtcaaca cgtcggcatg acgggctggt ccccacagga cca           893

<210> 225
<211> 438
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (366)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (421)
<223> n equals a,t,g, or c

<400> 225
gctccaaggt gcccacccct ggcagagccg kcctactgaa cacctctggt accaaaggct     60
tagaatgttc tccttcaact cccaccatga attcttactt ttataagttc atgatcaamc    120
ttctcaagag attcagcagc gaacggaagc tcctggargt cagaggccct ttcatcatca    180
ggtcagcctt ggcggcgcgc tttctcctct tcctcccacg gccccggctt ttcactttca    240
cgccattcaa gtgtcaaagc agccaccttc tctttccctt ctctctcctc cttttcctga    300
cctttggatc tgtgaagaga atggaagaag gttgcccctt ccatgactgg gttggctgga    360
tgcttnctgg acatggaaac aggacaggtt cagtgttgaa tgttttttgc cgcacaactg    420
naattcaatt ttttgctt                                                  438

<210> 226
<211> 1565
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1466)
<223> n equals a,t,g, or c

<400> 226
aatgttgaac tttttaaaga actcagtata aatgtcatga aacagctcat tggttcatct     60
aacttatttg tgatgcaagt ggagatggat atatacactg ctctaaaaaa gtggatgttc    120
cttcaacttg tgccttcttg gaatggatct ttaaaacagc ttttgacaga aacagatgtc    180
tggttttcta aacagaggaa agattttgaa ggtatggcct ttcttgaaac tgaacaagga    240
aaaccatttg tgtcagtatt cagacattta aggttacawt atattatcag tgatctggst    300
tctgcargaa ttattgaaca agatgctgta gtaccttcag aatggctctc ttctgtgtat    360
aaacagcagt ggtttgctat gctgcgggca gaacaggaca gtgaggtggg gcctcaagaa    420
atcaataaag aagaactaga gggaaacagc atgaggtgtg gtagaaagct tgccaaagat    480
ggtgaatact gctggcgttg gacaggtttt aacttcggct tcgacctact tgtaacttac    540
accaatcgat acatcatttt caaacgcaat acactgaatc agccatgtag cggatctgtc    600
agtttacagc ctcgaaggag catagcattt agattacgtt tggcttcttt tgatagtagt    660
ggaaaactaa tatgtagtag aacaactggc tatcaaatac ttacacttga aaaggatcag    720
gaacaagtgg tgatgaactt ggacagcagg cttctgatct tccctttata tatctgctgt    780
aacttcttgt atatatcacc agaaaaaaag aattgaaaat aatcgtcacc cagaaaatcc    840
agaaaactga agatttcatc agttggaaac agtagcactt tgaaaacttt ttaggccagc    900
tttaatttaa tggccctact gatattcaca tcgaaggtga ctaacaatga caaaggcctt    960
atgaacctgt acagacaata cagaagatta ttcttatcct cattgcattt ctatgcatat   1020
gcgtaagaac attttaaagc caagaaaata tctgtcaaac catttctgtt agaacgatgt   1080
caattcatgc ttttaattta gcatcaatag aaaattgctg taggtaaatc tcacatttat   1140
ctgcaacaaa atatagattt aatttttagc ttaaactttg tttctacctt atgttagtgg   1200
acctcagtta tccatctgta aatttctttt tatttggcta aaataatcta aaagaataat   1260
ttggttggcc aattagaaat gcctttttca gttggtgtat tgaaagcttt cctttaacat   1320
tttcacctgc tcattgtgat tcctcctttt agtctaatat ctttccaggt catacttgtt   1380
tttaatcatt aaatattttc ttcctggktt tggagactar gctgataaac tttttttaaa   1440
acttaagcat tgtcattgct attttnttta atttgacttt cctaggagtt taagaacagt   1500
gaaagttagc tttgcacctt caaatgatct tgaatgaggg aaaaatcagt ttgatccaag   1560
gatat                                                               1565

<210> 227
<211> 1526
<212> DNA
<213> Homo sapiens

<400> 227
aattcccggg tgtgtgtctg tgtctgtctg tgtctcgcat ggcgcgcggc cccggacaag     60
cgctggggat tyccgtttra ggcgtcacta ctgtcactgc catcacccca cggagccmct    120
tctagagggg agtagacccg gcccttcgcc gggcagagaa gatgttgccc ctgtccatca    180
aagacgatga atacaaacca cccaakttca atttgttcgg caagatctcg ggctggttta    240
ggtctatact gtccgacaag acttcccgga acctgttttt cttcctgtgc ctgaacctct    300
ctttcgcttt tgtggaacta ctctacggca tctggrgcaa ctgcttaggc ttgatttccg    360
actcttttca catgtttttc gatagcactg ccattttggc tggactggca gcttctgtta    420
tttcaaaatg gagagataat gatgctttct cctatgggta tgttagagcg gaagttctgg    480
ctggctttgt caatggccta tttttgatct tcactgcttt ttttattttc tcagaaggag    540
ttgagagagc attagcccct ccagatgtcc accatgagag actgcttctt gtttccattc    600
ttgggkttgt ggtaaaccta ataggaatat ttgttttcaa acatggaggt catggacatt    660
ctcatggctc tggccacgga cacagtcatt ccctctttaa tggtgctcta gatcaggcac    720
atggccatgt cgatcattgc catagccatg aagtgaaaca tggtgctgca catagccatg    780
atcatgctca tggacatgga cactttcatt ctcatgatgg cccgtcctta aaagaaacaa    840
caggacccag cagacagatt ttacaaggtg tatttttaca tatcctagca gatacacttg    900
gaagtattgg tgtaattgct tctgccatca tgatgcaaaa ttttggtctg atgatagcag    960
atcctatctg ttcaattctt atagccattc ttatagttgt aagtgttatt cctcttttaa   1020
gagaatctgt kggaatatta atgcagagaa ctcctcccct attagaaaat agtctgcctc   1080
agtgctatca gagggtacag cagttgcaag gagtttacag tttacaggaa cagcacttct   1140
ggactttatg ttctgacgtt tatgttggga ccttgaaatt aatagtagca cctgatgctg   1200
atgctaggtg gattttaagc caaacacata atatttttac tcaggctgga rtgagacagc   1260
tctacgtaca gattgacttt gcagccatgt agtgaatgga aagaaattat gcacctttta   1320
tggaccaaat tttyctgcca gtaagaattt cagttgtggg cctccagtct tctggaatgt   1380
cttcactgca gctgctggaa atcactgctt tcattcccac aaaaccagta ttactttttt   1440
ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1500
aaaaaaaaaa aaaaaaaagg gcggcc                                        1526

<210> 228
<211> 885
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (63)
<223> n equals a,t,g, or c

<400> 228
gcacctgcgt ggtgtgcngn ggtggagcng gggctggagg gagagttaat gatttgccac     60
agntcatttc gcaacttaac caatggacgc tttcccgtga ccatgtacca gctgcgtcct    120
ctgggccacg ctccacttgc ccgcttccac ccggaaagcc ccccaggctg agtgcggcat    180
gatctccatc accgaatggc agaagattgg tgtggggatc accggtttcg gcatcttctt    240
catcctcttt ggaacactcc tgtactttga ttccgtgctc ctggcctttg gaaacctgct    300
gttcctgacg ggcctgtccc tcatcattgg cctgaggaag accttttggt tcttcttcca    360
acggcacaaa ctcaagggaa ccagcttcct cctggggggt gtggttatcg tgctcctacg    420
ctggcccctc ctcggcatgt tcctggaaac ctacggattc ttcagcctct ttaagggctt    480
tttccctgtc gccttcggyt tcctgggcaa tgtctgcaac atccccttcc tgggtgcgct    540
gttccggaga cttcaaggca ctagctcgat ggtctgaaaa acagagatga gctccttgaa    600
cttggatcat tggttgaggg ggctagaggg agaatgggaa ccaccccctc agtcccctgc    660
actgactcac tccccgacat atccggacct ccccaagtcc agaaggaagg aatggagctg    720
agcaactgac gtcaaatccc caagtcgact caagaggctg ccaggaagca gagatgcaga    780
ccccaaggag actgggctgg ggctggtatc acaccctcac tctatattta tgggaggaaa    840
agtgaagatt aaattcccaa gttgtgcgtg tgtctaaaaa aaaaa                    885

<210> 229
<211> 456
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (422)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (452)
<223> n equals a,t,g, or c

<400> 229
caaccaccca aagagcaccc gggcgggagg acgccgagca gggggtgttg cgggctggga     60
caggggcagc cacctcccga agatgcagga tggcagcaga ncagcagccg tccagccttt    120
cctaccgcac cacgggctcc acctacctgc acccgctcag cgagctcctg ggcatcccgc    180
tggaccaggt gaattttgtg gtatgccagc ttgttgctct gtttgctgct ttctggtttc    240
gcatctactt acgtcctggt acaaccagct ctgatgtccg gcatgcggtt gccaccattt    300
ttggcatcta ttttgtcatc ttttgtttcg gctggtactc tgtgcatctt tttgtgctgg    360
tgttaatgtg ctatgcaatc atggggcact gctagtgtat ccaatattca cagatatgcc    420
tntntttgta gcaatgggat atcttacaat angcca                              456

<210> 230
<211> 459
<212> DNA
<213> Homo sapiens

<400> 230
ctactttttc ttcagcaatt ccaacccctg aggccaatta acaaagctag tagattgctt     60
tctgtactta agcaactctt tgaaatcgaa taaaccaaat ttagaaatgg ggtaaatcag    120
cttcttaaaa acattcaaat cctggatgca gacttcgacg ctcttctttc aaattaaaat    180
tgcaagtcta atatcaatta tatatttcaa attagaacca cagagtttct ttaacttttc    240
aaattgtttt aattacaakg cacacrgtat tgcaaagatt acaaaattta agtttgmagt    300
taagtttaty ctycaacttg taaagctkga wattcygatt tttttcccyc taccmcctct    360
agtaataaac acactcaggc caacagaggt tatcgtgttg aaggtttgtg actgtgatct    420
tcaccagaga tttgagccta ggaccaagac cgctctgcc                           459

<210> 231
<211> 461
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (415)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (448)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (457)
<223> n equals a,t,g, or c

<400> 231
cggacgcgtg ggcgattgga tgcggcggcg gcggcggatc ccggagagcc ccggagtgag     60
cggagtagcg agtcggcaac ccggwggtag aaatatttct ktcatggctc attcaaagac    120
taggaccaat gatggaaaaa ttacatatcc gcctggggtc aaggaaatat cagataaaat    180
atctaaagag gagatggtga gacgattaaa gatggttgtg aaaactttta tggatatgga    240
ccaggactct gaagaagaaa aggagcttta tttaaaccta gctttacatc ttgcttcaga    300
tttttttctc aagcatcctg ataaagatgt tcgcttactg gtagcctgct gccttgctga    360
tattttcagg atttatgctc ctgaagctcc ttacacatcc cctgataaac taaangatat    420
atttatgttt ataacaagac agttgaangg gctagangat a                        461

<210> 232
<211> 566
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (545)
<223> n equals a,t,g, or c

<400> 232
gtcgtcctcc ccgaccgcgt cctgcagcag ctgccagtgg agccgcctga caaggactgc     60
catccaccat ggtgaagctg ggctgcagct tctctgggaa gccaggtaaa gaccctgggg    120
accaggatgg ggctgccakg gacagtgtgc ctctgatcag ccccttggac atcagccagc    180
tccagccgcc actccctgac caggtggtca tcaagacaca gacagaatac cagctgtcct    240
ccccagacca gcagaatttc cctgacctgg agggccarag gctgraactg carccaccca    300
raggaagggc gcagctgccc accgcacgga tgatcgcctt cgccatggcg ctactgggct    360
gcgtgctgat catgtacaag gccatctggt acgaccagtt cacctgcccc gacggcttcc    420
tgctgcggca caagatctgc acgccgctga ccctgggaga tgtactacac ggagatggac    480
cccgagcgcc accgcagcat cctggcggcc atcggggcta cccgctgagc cgcaagcacg    540
gcaangaaga agcccggcgg cctggg                                         566

<210> 233
<211> 447
<212> DNA
<213> Homo sapiens

<400> 233
aggggaatta tatgttaaat gcattgactg ccggtgcccc catttgttaa acaaagcaaa     60
gatcaactgc tcattacact gtggctgacg ggcgaagacc accgcagcgc attatgctgg    120
tacagaacac gataacgarg aaatgtcagt accgatgcat aagcagcgca gtcagccgca    180
gcctggcgtc accgcatggc gtgcggcgat tgatctctcc agcggacaac cccggcggcg    240
ttacagtttc aaactgctgt ggcacgatcg ccagcgttgg tttacaccgc agggcttcag    300
ccgaatgccg ccggcacgac tggagcagtt tgccgtcgat gtaccggata tcggcccaca    360
atgggctgcg gatcagattt tttatcagat cttccctgat cgttttgcgc gtagtcttcc    420
tcgtgaagct gaacaggatc atgtcta                                        447

<210> 234
<211> 1292
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (507)
<223> n equals a,t,g, or c

<400> 234
ggaagggtac agtgattaat agcccaaatt ccagagttga actgcctcca tctggatcct     60
tactttactc tgcatgtagt aggcaatctt aggtcaagaa agatttggaa acatgacgag    120
ggtctattac cgagaagcta tgggtgcatt tattgtcttc gatgtcacca ggccagccac    180
atttgaagca gtggcaaagt ggaaaaatga tttggactcc aagttaagtc tccctaatgg    240
caaaccggtt tcagtggttt tgttggccaa caaatgtgac caggggaagg atgtgctcat    300
gaacaatggc ctcaagatgg accagttctg caaggagcac ggtttcgtag gatggtttga    360
aacatcagca aaggaaaata taaacattga tgaagcctcc agatgcctgg tgaaacacat    420
acttgcaaat gagtgtgacc taatggagtc tattgagccg gacgtcgtga agccccatct    480
cacatcaacc aaggttgcca gctgctnctg gctgtgcmaa atcctagtag gcacctttgc    540
tggtgtctgg taggaatgac ctcattgttc cacaaattgt gcctcyattt ttaccatttt    600
gggtaaacgt caggatagag ataccacatg tggcaagcca aagatctatg cctctktttt    660
ttcaatgaga gagaaatagc aaatgttctt tctatgcttt cctcaccatc atcacagtgt    720
ttacaaactt ttgaaaatat ttagtctgkt acaaacttct gtcatgtagc tgaccaaaat    780
cctgcagggc cacagtcggc actgttattt gcttctttta atcagcaaag gcctcaagtc    840
ttaaaataaa aggggagaag aacaaactag ctgtcaagtc aaggactggc tttcaccttg    900
ccctggtgtc tttttccaga tttcartata ttctctgatg gcctgacagg cctattaagt    960
agatgtgata ttttctccca agatgacctc cattctcggc agacctaaga gttgcctctg   1020
agttagctct ttggaatcgt gaacacaggt gtgctatatt gtccttgtcc taactgtcac   1080
ttgccatggc ctgaatgttg gcttaactga atattgtatg aaaagacatg cctccatatg   1140
tgcctttctg ttagctttct ctgactcaag ctgtggggct cctctataca tgctatacat   1200
gtaatatata ttatatatat ttttgcaagt gaacaataaa acattaaaag atgctgtttc   1260
cctaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 1292

<210> 235
<211> 924
<212> DNA
<213> Homo sapiens

<400> 235
aacaacgagg catccacctc ttggttttgt ggcctctgtg gatgacgtct ctcaccttga     60
accagttcag agttggagta gcgcaggatc ctgtcttcag aggaggggcc gaagcgggtt    120
cctctgttgt caagctcttt ggaggtgcct ggctgctact actgtcccag agaggctaag    180
gtgtttcatt gtaacctgaa tggaccaagc tggtgtgacc ctgttggaaa actggcagta    240
tctaccaaaa gccgaacata cgtataaact gatccagcat tccactcctg gtttttccag    300
gtttggactg gatatcgktg aactcggtca agctggtata tttgaaccca aagacatcac    360
tgctgaagaa gaagaggaag aagtggaaat cttaaaagca ttcggaagta cctgacctcc    420
aatgtggctt atgggtctac aggcattcgg gacgtgcacc tcgagctgaa ggacctgact    480
ctgtgtggac gcaaaggcaa tctgcacttt atacgctttc ccactcatga catgcctgct    540
tttattcaaa tgggcagaga taaaaacttc tcgagtctcc acactgtctt ttgtgccact    600
ggaggtrgag cgtacaaatt tgagcaggat tttctcacaa taggtgatct tcagctttgc    660
aaactggatg aactagattg cttgatcaaa ggaattttat acattgactc agtcggattc    720
aatggacggt cacagtgcta ttactttgaa aaccctgctg attctgaaaa gtgtcagaag    780
ttaccatttg atttgaaaaa tccgtatcct ctgcttctgg tgaacattgg ctcaggggtt    840
agcatcytag cagtatattc cmaakataat tacmaacggg tcacaggkac tagtcttgga    900
ggaggacttt ttttggtcct gctg                                           924

<210> 236
<211> 1256
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1149)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1235)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1237)
<223> n equals a,t,g, or c

<400> 236
aattcggcac agtactatat tgaggttaaa aggtgcaatc ttgagaatgg catttctgga     60
taccacaggc tgcttaatac cacctgcgta tgaaccctgg agagagcaca atgttcctga    120
agaaaaagac gaaaaggaga aattgaaaaa acggcggcct gtctcagtat ccccctcctc    180
ttctcaggaa attagtgaaa accagtatgc agtgatatgt tctgaaaagc aagcaaaagt    240
aatctcactg ccaacccaga actgtgctta taagcaaaat attacagaga cctcgtttgt    300
gcttcgtgga gatattgtag cattgagtaa cagtatctgc cttgcctgtt tctgtgccaa    360
tggacatata atgactttta gtttgccaag tttaagacct ctgttggrtg tgtattactt    420
gccccttacc aatatgcggr tagccagaac gttctgcttt accaacaatg gacaagcatt    480
ataccttgtt tcacctacag aaatccagag acttacttat agtcaagaga cctgtgaaaa    540
tcttcaggaa atgttgggtg aactcttcac tcctgtagaa acacctgaag caccaaacag    600
gggattcttt aaaggcttat ttggaggtgg tgcacaatct cttgacagag aagaactatt    660
tggagaatcg tcctcaggaa aggcttcaag gagccttgca cagcatattc ctggccctgg    720
tggcattgaa ggcgtaaaag gggcagcatc tggagttgtt ggtgaattag cacgagccag    780
gctggcacta gatgaaagag ggcagaaact tggcgatctg gaagaaagaa ctgcggccat    840
gttatcaagt gcagagtcat tttctaaaca tgctcatgag attatgttga aatacaaaga    900
taagaagtgg taccagttct gacaaccaga atccaataag tccaacttca gccagaagga    960
aaaaagtttt ccatttttat tacattcttt aggaaagtta acgttaaagg gatgttcgtc   1020
actgaatact gttctttcct agcacagtca tgcactgttt tacctcagtc atgtggcttt   1080
aactgaggag tgttcacacg cactcgaaat ggagtatatg gtgtgtgcca gttatgagtt   1140
gaccatttng gaattaaaca ggtcacacgt gacagatgaa gaaaccaagg ggctgctgaa   1200
gagacctggt gcaagggact aatcctggat ccatncngta attaaccttc catatg       1256

<210> 237
<211> 848
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (784)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (787)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (835)
<223> n equals a,t,g, or c

<400> 237
gctcgtgccg aacgcgtcgg ccacgggccc gggagagacg cgctccagcc ggccccagga     60
tgtaggcgat cggcggcagc gctcctgcag gcggccggct catcatgaag aagcactcgg    120
cccgggtggc cccgctcagc gcctgcaaca gtccggtcct gacccttacc aaagtggaag    180
gggaggagcg cccccgggac tccccgggcc cggcggaggc ccaggcaccg gccggggtgg    240
aggccggcgg gagagcgagt cgccgctgct ggacgtgctc ccgggcgcaa ctcaagaaga    300
tcttctgggg cgtggcggtc gtgctgtgcg tgtgctcctc gtgggcgggc tccacgcagc    360
tcgccaagct gaccttcagg aagttcgacg cgcccttcac cctcacgtgg tttgccacca    420
actggaactt tttattcttc ccgttgtact acgtggggca cgtctgcaar tccacagaga    480
agcagtctgt gaagcagcga tacaggtagg cgcgtcctgc atgaggaggc ctcctgaccc    540
cgggctgctc catccagcgc tgactccgca gagctgcccc tggtggcagg cgctgggatg    600
agccggtggg agcccgtgga gagatgttgc agtgaatgca cctgctctca gtggggtcgg    660
gagcagaatt ctgtctaccc tgggtagtga acgcctcctt cctctacctc cttgcccctc    720
agccctgggg agcccctttt atataaaagc aggcagcagc gtctttccag agacgggcaa    780
ttantangtt ccccagaacg ctttagaaat ggggagaact gttgtagctc cattnaatcc    840
ctaagcaa                                                             848

<210> 238
<211> 1206
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<400> 238
tgattcgtag cacgcttgct tgcatcctgg aatattctca accagaagac tctgtaccta     60
cacctgatga agtaagcatg ctaacagcaa ttgcactctt cctgtggtct gctagtaatg    120
aaataatagg agtccagtca ttacagaatg gctgcatgaa cagatttaaa aatgcattaa    180
attcatgcga cccatgggtt caagccaaat gttaccagct tctcctctca gtcttccagc    240
attccaatcg tgccctttca actccttata ttcattcatt agctccaata gtggttgaaa    300
agctaaaagc tgttgaaaga aacagaccag ccagtaacat agagctttta gcggttcaag    360
aaggaataaa agttcttgaa acactggttg ctcttggtga agaacaaaac agagtccagc    420
tacttgctct tttagttccc actttgatat cttacctgct ggatgaaaat tcttttgcct    480
cagcaagttc agcttccaaa gatcttcatg agtttgcact ccagaattta atgcatattg    540
gacctctgta tccacatgct ttcaagacag taatgggggc tgctcctgag ttgaaagtgc    600
gtctagaaac tgccgttcga gcaagccaag cgagcaaagc taaagcggct gccagacaac    660
cagcccccgc catacattct gcaccaacaa tttaagctaa aaaacaagtt ttttttnaat    720
ttgtaatttc atttatttgt atttatgttg tcaactagcc cctaattagt gatggccact    780
gtatcattcc aggctaccta tgggttctgt tttatttgta tattggtatt atagtgcttc    840
caagtaggtt aagtgaaata atgctcacac cacttattga tttttaagga gtgatttttt    900
ttatcatgtg gtgaatatgt tttcattttc ctcctaataa tgtttctctt ttgttaactt    960
atttattttt caaacactga gccatagtct taaatttaaa tgctaaaaac aattgtatca   1020
tgtagtcggg cagcctattg atactgtcag gggaaaaaaa tgggtcagaa ctcagcatct   1080
gtcatgaaaa aaatcaattg aaaaacaagc agattttaaa ttttgaagta atcaaaataa   1140
tggaaagtgt ctgttttgtg gtgtatatac tatgaataaa atcacagcat tttctaagca   1200
tttccc                                                              1206

<210> 239
<211> 449
<212> DNA
<213> Homo sapiens

<400> 239
gcttccgctc ccggcgcagg cgctgcagct tggccagagc ggagggggct cgggagagga     60
gtggacgccg ctggccagga tggtgctgga gagcgtggcc cgtatcgtga aggtgcagct    120
ccctgcatat ctgaagcggc tcccagtccc tgaaagcatt accgggttcg ctaggctcac    180
agtttcagaa tggcttcggt tattgccttt ccttggtgta ctcgcacttc ttggctacct    240
tgcagttcgt ccattcctcc cgaagaagaa acaacagaag gatagcttga ttaatcttaa    300
aatacaaaag gaaaatccga aagtagtgaa tgaaataaac attgaagatt tgtgtcttac    360
taaagcagct tattgtargt gttggcgttc taaaacgttt cctgcctgcg atggttcaca    420
taataaacac atgaattgac aggagataa                                      449

<210> 240
<211> 1262
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1261)
<223> n equals a,t,g, or c

<400> 240
aaaactgatt tgaaactttc acagatctca gcttttccaa gtaagtccac agaccatttg     60
ataggctaag cccagttctt tacacaatgt agcagccatc atgtctgagt actaattgtt    120
ctcttcccac tgggcttagc ctatcaagta agtccacaga ccatttgata ggctaagccc    180
agttctttac acaatgtagc agccatcatg tctgagtact aattgttctc ttcccactgg    240
tttttgtgaa attttctgtt ctgttacctt ttaaagattc ctagcaagtt tttgactgtt    300
tcaattgcaa acttattgct tttcttcttg gtaaaggact ttctgtttgg agcagatggt    360
agcaataggg ataccagccc ccagggccga ttacttgata tggaaggtcg atctgtatct    420
tcctgttgta aaatccaggc actttctcgg gccaaatcta caaatttttg cagctggctt    480
tgacttacat ttttgcttat gttgagagaa gtttcaaatg gattctgaat gtacagagga    540
gaagaatcag gtttgttttg ctcccttccc tgtcgaatat ttatggaatt tttatcgaaa    600
gcaaaattgc caaaatactc aaaaaattcc ttcagtagta attctaatgt ttctgtgttc    660
tgtgaaggtt taattctact caagtcacga acaaatgtgc agttgttgcc ttctattaca    720
catttatctt ctgcatctgc tagggttttt aaggaatcta gtgttggaag aatagggggt    780
gatcttctct ggagaaaaaa gatgaccatc attgtaaggg agaaatttgt aatccatgca    840
ccaggaatac tacttgttag tgaatgtgct cgagcccagc accgtacact garcaccaag    900
gctctcactc ttgagtctag ggcaccatat atataaagga gttcggaact tgtcaaggca    960
atcctattgt tcgtagtcaa atcacactga aatccggagg cctggtgtga gaacctcacg   1020
agcggacacc gggcatttaa tattttttgc acacccacac agccagggcc aaagtggtca   1080
aggcactctc ctaacacaga caggatcttc tgagttgcaa ttctttctga aggaacattt   1140
ttcacttgaa attccatcag aaaatttcct gagatcttgt gagcgctgag gtttctggtt   1200
tcatctagat ccaaaaacat gtccaaatca catcctaact tcccaaaagt gttgacctga   1260
ng                                                                  1262

<210> 241
<211> 1439
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1384)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1427)
<223> n equals a,t,g, or c

<400> 241
cctggggcgg agtttgggct gactggggct ggaccgggca agacgccgcc gctgcccgga     60
tgttgcgatg gctgatcggg ggaggccgag aaccgcagga ctggccgaga aatctccttt    120
acagacaata ggtgaagaac aaacccagaa tccctacact gaactgctag tactgaaggc    180
tcatcatgat attgtacgat ttctggtaca gttagatgac tacagatttg catctgctgg    240
tgatgatgga attgtagttg tgtggaatgc ccagacaggg gaaaaacttt tagaactgaa    300
tggacacact caaaagataa cagctattat tacatttcct tccttggaat cttgtgaaga    360
gaaaaatcaa ctcatcttga cagcctctgc tgatagaaca gttattgtgt gggatggtga    420
tactaccaga caagttcaga gaatatcatg cttccagtct actgtaaagt gtttaactgt    480
tcttcagaga ctagatgttt ggctttctgg tgggaatgac ctgtgtgtgt ggaaccgaaa    540
attagatctc ctgtgtaaga ctagccacct ttctgataca ggtattagtg ctttggttga    600
aatacctaag aactgtgttg tggcagcagt tggcaaagaa ctgataattt tcaggttggt    660
agcacccaca gaaggatcac tagaatggga tattcttgaa gttaagcgcc tccttgatca    720
ccaggataat attctctcat tgattaatgt caatgatttg agttttgtca ccggctccca    780
cgtcggagag ctgatcatct gggatgccct ggactggacc atgcaggcct atgaacgcaa    840
cttctgggac ccatctccac aactggacac ccaacaagaa ataaaactct gtcaaaaatc    900
aaatgacatt tctattcatc atttcacatg tgatgaagag aatgtatttg ctgcagttgg    960
aaggggttta tacgtgtata gccttcaaat gaagcgtgtg attgcctgcc agaaaactgc   1020
acatgactcc aatgtcctgc acrttgccag acttccaaac aggcagttaa tctcatgctc   1080
agaagatggc agtgtacgca tttgggagtt aagagaaaaa cagcagcttg cagctgagcc   1140
tgtaccaaca ggttttttta acatgtgggg atttggaaga gtcagcaaac aagccagcca   1200
acctgttaaa aagcagcaag aaaatgctac ttcatgttca ctggagctta ttggagattt   1260
gattggacac tcatcatctg tggagatgtt tctatacttt gaagatcatg gactagtgac   1320
gtgctccgct gatcatctca ttattttgtg gaaaaatgga gagcgagaat ctggattgcc   1380
ccantttaag attatttcca aaatttaggg gggaatgggg gccttanacc tggcggcca    1439

<210> 242
<211> 829
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (800)
<223> n equals a,t,g, or c

<400> 242
ctcgcgcttg ggctcgcgat ggggaagaag tcccgggcgg tacccggacc gtanncaatc     60
ctgcaactct ctccgccggg tcctcggggc agcacgccgg gccgggaccc ggagccggaa    120
cccgacactg agccggactc aaccgcggcg gtccccagcc agcccgcccc gtcggcggcg    180
acgaccaccg cggtgactgc cgccgcggcc tcggacgact cgccttcaga aggcaaggat    240
gaacaggaag cggtgcagga ggttcctaga gttgttcaga atcctccaaa accagtcatg    300
accactagac ccacagctgt taaagcaaca ggtatgcttt tgttttgttt tttacatttt    360
ttctcccacg tctttcatta aagtcaagtt gggtttgtac atagaatgtt ttgctgaatg    420
ctttagtgtt gctaacatta tttctcccaa aaatatgatt taagattatt tttgtttgtg    480
agagaatgtt gatgtatata cactttgacc agtgcaaaat ttgttgtttt tctttaccca    540
aaacgttttt tactgttttt ttttcctgat gctattttat aactagtttt ctggtcctcc    600
cactagcttg gtgttcatta ggcatgccaa ctcctattcc ttttctaaca ctctggcttg    660
attggttacc taacaaacat tggtggacct ggaaattgrt cttrttaaaw atttcaagta    720
caaaggaatg ccatagtygc aacagtggtt ttgtagacaa accgggttca atycatcagc    780
tggcatcaca cttagacttn gcgcaatacc aatgggtgaa cctcattaa                829

<210> 243
<211> 1496
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<400> 243
tagcctttga aaanctgaac ccctactcaa ccccgtctcc accacaccca ctgtatcctg     60
gccgcarggt aatasagttc tctgaggata aggttcggat cccccgcaac agccccctgc    120
ccaactgcac ttacgctacc cgccaggcca tttccctgag cctggtagag gaggggagtg    180
agcgggcccg cccagcccag tgcccagcac ccctgcctca gcccaggcct caccccacca    240
ccagcccagc ccagcacccc taacactcag tgccccagct agctctgcca gctctgaaga    300
ggacctgctg gtcagctggc agcgggcatt tgtggaccgt actccaccac ctgctgctgt    360
ggcccagcgc acagcctttg gacgcgaatg ccctccctga gctgcagcgc cattttgccc    420
atagccccgc tgacagagat gaggtggtcc aggcaccttc tgcccgaccc gaagagagtg    480
agcttttgct acccacagaa cctgactctg gctttcccag ggaggaagaa gagctgaacc    540
tgcctatcag tcckgaggaa gagcgccaga gcctgctgcc cattaacagg ggcacagagg    600
aggggccagg cacttcccac accgagggca gggcctggcc actccccagc tccagtcgcc    660
cccagcgcag ccccaagagg atgggggttc accacctgca ccgcaaggac agcctgaccc    720
aggcccagga gcagggcaac ctgctcaact agggcccctg ctggccttcc tgccattgct    780
gcaccaggac tgcaaggagt ccccacacct tggcagctca gggtccccag tccaagccct    840
tgacctctcc tctatccaga cccgcacagc tgtttcctgt gtggatgggg tcaggttgtg    900
ggccatgcca ggcctgtcag ctgcgttgac tgactgcagc agcttgcctc atggttttcc    960
ctttttctta gaatatttat tcttcagagg taacatgcag ttgggtctca agacctttcc   1020
tccaatcagc ccaacccagc ccagactggg cttttctggg gagctgagga gtttatcagt   1080
attcatcttc catcctttca tagtcacaag ttttgttatt ttgttttttt ttgggggtga   1140
tggtgtaatt gttaacctca tttccgtttc ctacctgttt gcttcccccc ccagtcctcc   1200
gcatgagctg ttgccctcca ggggcctggc acagctggcc ttggggacga gggagaggac   1260
tgattcaggg ccccctcagc tgtctcctcc ctccctctgg aaaggagggt ggggctcagg   1320
ggcctcaagc tgggctctgt gtgaggcctg gcccccactc ccaaccttgg ctctagactg   1380
ttactcttaa gctttgagaa attttcacat tgatgactat tttaaaatca aataaaacta   1440
ttttactggt aaaaaaaaaa aaaaaaaact cgaggggggc ccgtacccaa tcgcct       1496

<210> 244
<211> 1158
<212> DNA
<213> Homo sapiens

<400> 244
cgctctagaa tatggatccc cgggctgcag attcggcacg agcagagatc cgagatgcat     60
tcaaaatccc aatgacattc agcttcaaga aaaagcttgg aatgcggtgt gccctcttgt    120
tgtgaggcta aagagatttt acgagttttc cattagacta gaaaaagctc ttcagagttt    180
attggaatct ctgacttgtc caccctacac accaacccaa cacctggaaa gggaacaggc    240
cctggcaaag gagtttgccg aaattttaca ttttaccctt cgattcgatg agctgaagat    300
gaggaacccg gctattcaga atgacttcag ctactacaga agaacaatca gtcgcaaccg    360
catcaacaac atgcacctag acattgagaa tgaagtcaat aatgagatgg ccaatcgaat    420
gtccctcttc tatgcagaag ccacgccaat gctgaaaacc cttagcaatg ccacaatgca    480
ctttgtctct gaaaacaaaa ctctgccaat agagaacacc acagactgcc tcagcacaat    540
gacaagtgtc tgtaaagtca tgctggaaac tccggagtac agaagtaggt ttacgagtga    600
agagaccctg atgttctgca tgagggtgat ggtgggagtc atcatcctct atgaccatgt    660
ccaccctgtg ggagctttct gcaagacatc caagatcgat atgaaaggct gcataaaagt    720
tttgaaggag caggccccag acagtgtgga ggggctgcta aatgccctca ggttcactac    780
aaagcacttg aacgatgaat caacttccaa acagattcga gcaatgcttc agtagagctc    840
tgctcaaaga agaggatcta tgtgctgacc tcagaagatg tatatgttta cataatttaa    900
tacagattga tgttaatact tgtgtattta cataaccgtt tccttcttgt cactgaaata    960
tatggacctt aatttgtatc ctgactgact caacccagca gagcataaat tgacttgaga   1020
gccttacctt tgatgtctga aatgaaaccc ccttctccaa aggcaaaatt cggagacttt   1080
gatctttgct actggagtcc tttaacaaca tctataacga taaaaaattc ctaattgttt   1140
gtggtarwaa aaaaaaaa                                                 1158

<210> 245
<211> 791
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (630)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (639)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (731)
<223> n equals a,t,g, or c

<400> 245
gactcagtgg acgacggcgg cggcggcgaa acgggatgaa gaccccggar ccaacttgtt     60
tccggtgagg cgggacagtc tggtctgctc gtgaatattt ataaaccggc tcccccgcag    120
cgccacctgt cattatgctt actaacgttc gggacgtctc ccgggctgct tgggcgagga    180
gaggcagggg tgtgtgaccc cggtggttac tgtgctcgcg tagagcacyt agggcctgct    240
gaagccctcc ctcgcccgcg cctctcctta gtccttgaga tgagatggca agttacagcg    300
gcttctccgg cctgctggag attcgctacg ggccaggaca ccgcagctgc cttccccaat    360
tcgctttctt tccgcagccg ccgctgcccc gaccccggat ctgcatgtkg gtgctggctg    420
agctgctgga gctarggtgt cctgagcaga gcctgargga cgccatcamc ctggacctct    480
tctgccacgc gctcattttc tgccgccagc agggcttctc actggagcag acgtcagcgg    540
cttgtgccct gctccaggat cttcacaagg cttgtattgg ccacatccac gtcctccgag    600
cctacatcaa gacccaagtg aacaaagagn tggagcagnt ccaagggntg gtggaaganc    660
ggctcaaggc cagcgaagaa aggttcagca gcaattgaat gcataaaagc ggccttccag    720
taactccggt naaaggcaaa gcagaccaat gaccccaaat tttcccataa aagtttgggc    780
aaatgggaca t                                                         791

<210> 246
<211> 1960
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (60)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (885)
<223> n equals a,t,g, or c

<400> 246
ctgcccccat agtnncncac tccctaaant ccagagccag ttcggttccc ttctaggtgn     60
ccaataaaag tgaccaaagt ggtcattttc ttaatttcat tctgatcagt gtctagcaag    120
gatgatgacc taacatgatc tccagcttag actgtaagcc cgatttctcc tcctcatttt    180
ctgatacctt tactaggacc tcaagtgcmc ttctgggatt gagtgacacg ttaacacaga    240
agaagcccag aagacgcccg acagaacctt ctccctgagc gtcccctccc ctctccctac    300
ttccgatcaa ctgttgcacg gcaaactgca aacgtagagc aaattccact aagatggtgt    360
caaaaagaga taattaaaga aaatwaatga tggaaaactt gcctcttatc twagraatta    420
ttctataaat atmtcccagt tcaaagattt gacttttggt tgtctgggga ccattcctcg    480
ctagggacat ttcaagaaaa actctcccca tctggatgac tttgttttca tttatgctat    540
taaggataac cgtacgcaga tccaaaataa cagaggacgt cattttattg gctgtccacg    600
ggaagtttca tcacacacgg aggtgaagac tgtgggggtt gtggcacaca atatctcaac    660
acgagacctc atcgagcggc caaacagaag gtgaagtgac acccgacacg acggaacccc    720
agccgccctc tgcagccccg gtgccacctc tccacagacg cctcagccca gtaagctgag    780
tgatgacact gtccattagt ctcagttcgt tgcactgtct tccaacaaaa cagcacttga    840
aaattcacaa aattaaaaaa agaaaaagaa agcagcactt ccttnggaaa tagcaacacc    900
actgtaacac agacggcagc gtggcatgca gatccacacc tggtcggttt tttcccttta    960
ggattttttt tttttttaat taacaaatgg aatggcaggt ctgtttcaaa tattagtagc   1020
ataacacata agtgcaattg cagtctggcc acaagcgtca gaagccttcc gtgtgtctgt   1080
cacaagggcg ggcagacaca ctccgattcc acccctggag ggtcaccaaa agaaagcagc   1140
cacttctcta tttccattgt tgtcaaagca ctcaggttgg ggaagaaaat tcaaatgaaa   1200
ccaagctctc agcatccggg gccagccacc ctgtgccatc ctaagtggtc tctgtacccc   1260
agacctgggg ctgtcatctc caccgtggca ttggctggga aagtcgctgt gggacacacc   1320
cctccgctca ctcctgctgc ccatggagga gcctctggtg tcccccggcc tggggccatg   1380
tgggtcacac ggagctgagc ttcaccaggc cgcgcacaga gtcctcatgc agggagtccc   1440
tggctggcca ggcccagcac gtgcatggtg cggctgtgcg ccagggggct gcccgccgcc   1500
agtagcctgg gggcgagggc cctcatcggg cgtcaggaac tggtggccca tgtgctcatc   1560
tttccggggc atcacgtccg cgagcgtggc ctcggcgagg ttgggcatgg aggcgggcgg   1620
tgtgggcggg cccagtgtga ggctggcgca gggcgtgccc aggccaggct tcccgggcag   1680
gtgcagctcg tcgctggtga ggctgggctc gctctgcagc aggggcgtgc tgcagccacc   1740
acttccagac caccaaaggt aatcctctca gtgcaagccc aaattctcct ttttcttttc   1800
tcctaacgat gtagaatcct ttctccggtg ccagaacagt gatggcaaca ccattccaag   1860
ggaagtgggt agtcctggac cttacagatg aggaaactga ggtgcaaagc agtcagctgt   1920
tttgcccaag atcttgaggc cagtgagtgt cccaggcagg                         1960

<210> 247
<211> 383
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (349)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (366)
<223> n equals a,t,g, or c

<400> 247
gtaccatata tacacaaata cacatatgtg tgtgcatata tatatgtata tactgtgtgt     60
gcatatatat atactgtatg catgtatata tactgngtat acatacacac tgtgtgtata    120
catatataca cactgtgtgg tgktatacgt atatacactg tgtgtgtata cgtatataca    180
ctgtgtgtgt atatatatac atatactctg tgtgtgtgta tatatataca tatactctgt    240
gtgtgtgtgt atatgtatat actgtgtgtg tatatatata gcaggttata tatatacgtg    300
tatacatata tatgtgtgtg tggtatatat atatacacac acacacacna tgcacacaca    360
gtagcngggg tggcacttgg aag                                            383

<210> 248
<211> 765
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (744)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (749)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (755)
<223> n equals a,t,g, or c

<400> 248
ctgatatgcc aaagcctgcc tttcatgaag cagaacctgg atgagcttgg aataggaacg     60
taccacaaca ttgccttcat acatccagac actcccatca tcaaagcctt gaacatattt    120
gtggaaagac gaatatcagc tctgcctgtt gtggatgagt caggaaaagt tgtagatatt    180
tattccaaat ttgatgtaat taatcttgct gctgagaaaa catacaataa cctagatatc    240
acggtgaccc aggcccttca gcaccgttca cagtattttg aaggtgttgt gaagtgcaat    300
aagctggaaa tactggagac catcgtggac agaatagtaa gagctgaggt ccatcggctg    360
gtggtggtaa atgaagcaga tagtattgtg ggtattattt ccctgtcgga cattctgcaa    420
gccctgatcc tcacaccagc aggtgccaaa caaaaggaga cagaaacgga gtraccgccg    480
tgaatgtaga cgccctagga ggagaacttg aacaaagtct ctgggtcacg ttttgcctca    540
tgaacactgg ctgcaagtgg ttaagaatgt atatcagggt ttaacgatag gtatttcttc    600
cagtgatgtt gaaattaagc ttaaaaaaga aagattttat gtgcttgaag attcaggctt    660
gcattaaaag actgttttca gacctttgtc tgaaggattt taaatgctgt atgtcattaa    720
agtgcactgt gtcctgaagt tttncttant ttccnttcaa gatcc                    765

<210> 249
<211> 1419
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1406)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1408)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1413)
<223> n equals a,t,g, or c

<400> 249
ggcacgaggn ctggggcggg aggatgctcc agaggggcct ctggccgtgg cgcacgcggc     60
tgctgccgac ccctggcacc tggcgcccag cgcgcccgtg gccgctgccg cctccgcccc    120
aggttttgcg tgtgaagctg tgtggaaatg tgaaatacta ccagtcacac cattatagta    180
ccgtggtgcc acctgatgaa ataacagtta tttatagaca tggccttccc ttggtaacac    240
ttaccttgcc atctagaaaa gaacgttgtc aattcgtagt caaaccaatg ttgtcaacag    300
ttggttcatt ccttcaggac ctacaaaatg aagataaggg tatcaaaact gcagccatct    360
tcacagcaga tggcaacatg atttcagctt ctaccttgat ggatattttg ctaatgaatg    420
attttaaact tgtcattaat aaaatagcat atgatgtgca gtgtccaaag agagaaaaac    480
caagtaatga gcacactgct gagatggaac acatgaaatc yttggttcac agactattta    540
caatcttgca tttagaagag tctcagaaaa agagagagca ccatttactg gagaaaattg    600
accacctgaa ggaacagctg cagccccttg aacaggtgaa agctggaata gaagctcatt    660
cggaagccaa aaccagtgga ctcctgtggg ctggattggc actgctgtcc attcagggtg    720
gggcactggc ctggctcacg tggtgggtgt actcctgggr tatcatggag ccagttacat    780
wcttcatcac atttgcaaat tctatggtct tttttgcata ctttatagtc actcgacagg    840
attatactta ctcagctgtt aagagtaggc aatttcttca gttcttccac aagaaatcaa    900
agcaacagca ctttgatgtg cagcaataca acaagttaaa agaagacctt gctaaggcta    960
aagaatccct gaaacaggcg cgtcattctc tctgtttgca aatgcaagta gaagaactca   1020
atgaaaagaa ttaatcttac agttttaaat gtcgtcagat tttccattat gtattgattt   1080
tgcaacttag gatgtttttg agtcccatgg ttcattttga ttgtttaatc tttgttatta   1140
aattcttgta aaacagaagt attgtttgaa gttctcaact gagattttta ctttttggat   1200
ttttatgact tgctaatgtt agaaagggct tgtatgcgtc tatcaaagca acagtggctg   1260
ctgttagcta aaaatccttg tcagcttgtc ccacgtttat tctctatgtg gaggtgaaag   1320
ggtctgtgct tggcatccac ttccatctta gacttaattg ggaaccatcc ttctaaaaaa   1380
atcagagacc agtctggcca atcaancngg ggnccagca                          1419

<210> 250
<211> 987
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (350)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (735)
<223> n equals a,t,g, or c

<400> 250
gtaaaagggg atcgagttat gccagaggaa atagctcgct actataaaca ttatgtaaaa     60
gtcatgggtc ttcagaagaa tttcagagag aatacttaca taacttccgt atcaagactc    120
tacagagatc aagatgatga tgatattcaa gacagagata tttcaacaaa gcatttacag    180
atagagaagt caaactttat caagagaaac tgggaaatta ggggttatca gcgaatagct    240
gatggttctc atgttccctt ctgcctcttt gctgagaatg tagcgctggc aactggaacg    300
ctggattctc ctgcccatct ggaaattgaa ggggaagatt ttccttttgn gtttcattca    360
atgcctgaat ttggagcwgc tmyaaacaaa ggaaagttgc gtggcaaagt ggatccagtg    420
ttaattgtag gttctgggct tactgccgct gacgcagtac tgtgtgctta caacagtaat    480
atccctgtga ttcatgtgtt tcgcagacga gtaactgatc caagcttaat tttcaaacag    540
cttcccaaaa agctgtatcc tgaatatcat aaagtctatc atatgatgtg tactcagtca    600
tattctgtag actcaaatct tttatctgat tataccagct ttcccgagca ccgtgtgctt    660
tcctttaagt cggacatgaa atgkgttctc caaagcgttt ctggattgaa gaaaatattt    720
aagctgtctg cagcngtcag tattgatagg ttctcatcct aatctgtctt ttctgaagga    780
tcaagggtgt tacctaggcc ataagtcaag ccagccaatc acatgtaagg gtaatcctgt    840
ggaaatagat acatatacct atgagtgtat taaagaagcc aacctttttg cattgggtcc    900
tttggttgga gacaattttg ttcgattttt aaagggaggg gcgctgggtg ttacacgctg    960
tttagctaca agacagaaaa aaaaaaa                                        987

<210> 251
<211> 440
<212> DNA
<213> Homo sapiens

<400> 251
cggaagcaag tgaaatgctc agtcttagac gactgcgtcg tgctatgacc ggactttttc     60
ttgaaagggg atgacagcat gggaggcaat ggctccacat gtaaacccga cactgaaaga    120
caaggcactc tctccacagc agccccaaca actagccctg caccctgtct ctctaaccac    180
cacaacaaaa aacatttaat ccttgccttt tgtgctgggg ttctactgac actgctgctg    240
atagccttta tcttcctcat cataaagagc tacagaaaat atcactccaa gccccaggcc    300
ccagatcctc actcagatcc tccagccaag ctttcatcca tcccagggga atcayttacc    360
tatgccagca caamtttcaa aytctcagra graaagagca atcacttggc tgagaaccat    420
tctggcagac tttgacccca                                                440

<210> 252
<211> 1530
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (97)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (98)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (110)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1414)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1444)
<223> n equals a,t,g, or c

<400> 252
acgctggcgg nacgcgtggg ccggctaatt aatccccact catggatata ggcacacaaa     60
ctaaaggttc ttgcatacac tgagggactt cacgggnnaa tggatgtgcn gcgagatacg    120
agctgtattt tcaagacgtt accttctaca aaacactgct ttggaagtat ttatggcaaa    180
ccgaacctca gttatgttta atttccctga tcaagcaaca gtaaaaaaag ttgtctatag    240
cttgcctcgg gttggagtag ggaccagcta tggtctgcca caagccagga ggatatcatt    300
ggccactcct cgacagcttt ataaatcttc caatatgact cagcgctggc aaagaagggr    360
aatttcaaac ttcgaatatt tgatgktccy taatactatt gcaggacgga catataatga    420
tctgaaccaa tatccagtgt ttccgtgggt gttaaccaac tatgaatcag aagagttgga    480
cctgactctt ccaggaaact tcagggatct atcaaagcca attggtgctt tgaaccccaa    540
gagagctgtg ttttatgcag agcgttatga gacatgggaa gatgatcaaa gcccacccta    600
ccattataat acccattatt caacagcaac atctacttta tcctggcttg ttcgaattga    660
acctttcaca accttcttcc tcaatgcaaa tgatggaaaa tttgatcatc cagatcgaac    720
cttctcatcc gttgcaaggt cttggagaac tagtcagaga gatacttctg atgtaaagga    780
actaattcca gagttctact acctaccaga gatgtttgtc aacagtaatg gatataatct    840
tggagtcaga gaagatgaag tagtggtaaa tgatgttgat cttccccctt gggcaaaaaa    900
acctgaagac tttgtgcgga tcaacaggat ggccctagaa agtgaatttg tttcttgcca    960
acttcatcag tggatcgacc ttatatttgg ctataagcag cgaggaccag aagcagttcg   1020
tgctctgaat gtttttcact acttgactta tgaaggctct gtgaacctgg atagtatcac   1080
tgatcctgtg ctcagggagg ccatggaggc acagatacag aactttggac agacgccatc   1140
tcagttgctt attgagccac atccgcctcg gagctctgcc atgcacctgt gtttccttcc   1200
acagagtccg ctcatgttta aagatcagat gcaacaggat gtgataatgg tgctgaagtt   1260
tccttcaaat tctccagtaa cccatgtggc agccaacact ctgccccact tgaccatccc   1320
cgcagtggtg acagtgactt gcagccgact ctttgcagtg aatagatggc acaacacagt   1380
aggcctcaga ggagctccag ggatactcct tggntcaagc ccaccatctt cccattgaaa   1440
tggntccatt aatagccaat aattcaggtg taaacaaaac gggcagatca cagacctcgt   1500
tgaccagagt atacaaatca atggcacatt                                    1530

<210> 253
<211> 561
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (400)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (521)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (532)
<223> n equals a,t,g, or c

<400> 253
ggaactggga tttcagcaac tgaatgcacg tgtgtgacta cccacgagaa gcaggacact     60
tagcacctgc tgagaagccc ccacgcccat gttcccttct aggcactgca catgcatgct    120
ggccggcctg acctcagttt ccctcttgct gtggccgctt ctgctccact ctctgtgagg    180
ctcatccacc ttgttgcctg trgttgtgga ttgttcattc tcaagtgctc tgtatgccaa    240
gtactccatt gtgtgaaaat cccacagcac gttcattcta ttatcaatgg gcatttgggt    300
agtttccaca gtttggctgt taggaatagt gcagtgatga acatgctggc acctgtcttc    360
tgtttttttt ttatttttag agacagggtc ttgctctgtn acccaggctg gagtgcagtg    420
gtgtgaacct tggcttcgct gggcctcctg ggcttcaagc aatcctcccg gctcggtctc    480
ctgagtagct gggaactgca ggtgtgtgcc tgtgtgctgg ntaaattttt gnagtttttg    540
tagagatggt gtcttgctct g                                              561

<210> 254
<211> 1305
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1288)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1290)
<223> n equals a,t,g, or c

<400> 254
aatcctcagt ctggtctata ttgttacttg cctgtntcca ctagaaggag tcaccaggca     60
tttagtgaat gataatccta gaagttgagt stgagtacat cagagtttgg cattatttgc    120
aacatcccag gaatgagcta taagactcca ttgctttctg gactttagtg accagctgat    180
cttcccttgg atcctccaat aaaggggaaa aaatacttgt cttatgttgt tttagcaagg    240
gagttcagcc aagtgacagg aaagattccc tggtctgcat ctaaacatta gtcaacagaa    300
ggaaaaggct cttttccttg gagattttca agttgaaaaa gtacagctgc ttggatggag    360
tttctctcat cagaatagaa atatgctagg tggtcttcaa gacctttttg aacctacaga    420
ttctaaacct tagaggaagc cagaatatgt gatcatacca ggtgaggaaa gttaggagat    480
attcatctta agagatatcc tatttggcag tcacatgtta cacttgagca acaattgtct    540
aggctagaaa tatagaacca caatatttat catcattggg tcaatttctc cccctctatc    600
aagtgaggag attaaggctt aaagaaagga aaggacttgc cagccaccac agggctcatg    660
aggggcttga acccatgtcg tgtgtctcta ccacagctga ctctcagctg gctaatggag    720
aaaatgtgag gaattacctg tcaaattaga ttgagctcag agtaaataga tgagcacatt    780
tataactcta aattagactt tctatcaaat gggaccaaac atatggaagg ggctgctgtc    840
ctgcctcaat ttagccaaga cttgtcttgt ctcaaagcca agactcagca gtacatggat    900
tctgagaagt ccagggtctg aattgttgtc tctgattact ggaaggacag gttaactgaa    960
tgtctgtgat cactaacagg tgatgggctt tgtgcccact ccagagatat tgtgggagac   1020
aaattctttt aacagcctgt cctcccggca tcaggagtca ttgaacaatc atggattgtt   1080
gtgtttggga tttttttttt ttttggcttt gtttttggtt tttgtgtgtg tgtgtgtgtg   1140
ctgcatgcac atgcgtccaa gacttacggg tggtttaggg gaaagtgcta gcaacagtgt   1200
caatgtcatt gttaactata tttcatattt gaggtctcat tgttttcaaa taaacagtgt   1260
tttccatgaa aaaaaaaaaa aaaaaaantn ctgcggccgt caagg                   1305

<210> 255
<211> 538
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (346)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (478)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (537)
<223> n equals a,t,g, or c

<400> 255
gtaaatccgg ctggactttc agcttctaag aacagtccgt ttctcgagga tccaggcgca     60
ggaggacaga gcaatgggtg agagaactct tcacgctgca gtgcccacac caggttatcc    120
agaatctgaa tccatcatga tggcccccat ttgtctagtg gaaaaccagg aagagcagct    180
gacagtgaat tcaaaggcat tagagattct tgacaagatt tctcagcccg tggtggtggt    240
ggccattgta gggctatacc gcacaggaaa atcctatctc atgaatcgtc ttgcaggaaa    300
gcgcaatggc ttccctctgg gctccacggt gcartctgaa actaangggc atctggatgt    360
tgtgtgtgcc ccactctcta agccaaacca maccctggtc cttctggaca ccgagggcct    420
gggcgatgta gaaaagagta accctaagaa tgactcgtgg atctntgccc tggctgtnct    480
tctaagcagc agctttgtct ataacagcgt gggaccatta accaccaggc ctggagna      538

<210> 256
<211> 374
<212> DNA
<213> Homo sapiens

<400> 256
cctgagcctg tgccgtaatg cccgcccctc tccctcctcc gtctgcatgc agtcatctgg     60
ggacctggag aatgatgagc aggcagccag tgccatctct gagctggtca gcacagcctg    120
cggtttccgg ctgcaccgcg gcatgaatgt gcccttcaag cgcctgtctg gtgagcccct    180
gcccctgccc ttggtggtgg tactgggagc ggggggctac ttccaggggc ttctcggctt    240
ccctctcctg gggcggggga agtgtgtctc tcctccagtg gtctttggag aacacacact    300
gctggtgacg gtgtcaggac agagggtgtt tgtggtgaaa aagcagaacc gaggtcggga    360
gcccattaat ttct                                                      374

<210> 257
<211> 321
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (283)
<223> n equals a,t,g, or c

<400> 257
catgtacgga catattgaaa cgatggcacg cgcatcgctg agggtgcaag caaagtggat     60
ggcgctgaag ttgtcgttaa gcgtgtaccg gaaaccatgc cgccgcaatt atttgaaaaa    120
gcaggcggta aaacgcaaac tgcaccggtt gcaaccccgc aagaactggc cgattacgac    180
gccattattt ttggtacacc tacccgcttt ggcaacatgt ccggtcaaat gcgtaccttc    240
ctcgaccaga cgggcggcct gtgggcttcc ggcgcactat acngaaaact ggcgacgtct    300
ttagttccac ggtactggcg g                                              321

<210> 258
<211> 720
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (634)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (667)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (719)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (720)
<223> n equals a,t,g, or c

<400> 258
cgnaccncga acggccgcca gtgtgctgga nttcggctta gcgtggtcgc ggccgaggta     60
catttctatg aggtccatcg gcactgagaa gcactcgttt ttctttcatc ttgtagatga    120
tgtgctgagc ttcagctgtg gcaggggtcc ttttcagatg gtccttcact aaatcaattc    180
caataaaaag gccaatgccc ctaatatctc ctatcaaagt gtgtttagcc ttctgttttt    240
tcagtaactc agtgagataa ttccctactc tcttggcatt tccttgaagg tcttcatttt    300
caattatatc caggacagcc aaaccaacag cacaagatac tggatttcct ccatacgtat    360
taaaatattc catcccagag ctgctgaagg cttctgcaat ttctttggtt gttaccacac    420
atgccaccgg gtggccgttg cccatcggtt ttcccattgt gacgatgtct rgaacaaagt    480
cttcaccata catctggaag ctccagraat gtttcccaac tctgccaaag cccacttgaa    540
cttcatcagc tataaacaca ccycstgcac cgtgtacctg cccgggcggc cgctcgaaaa    600
gccgaattct gcagatatcc atcacactgg cggncgctcg agcatgcatc tagagggccc    660
aattcgncct atagtgagtc gtattacaat tcatggccgc gtttacaacg tcggatggnn    720

<210> 259
<211> 1717
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1072)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1596)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1634)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1657)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1702)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1712)
<223> n equals a,t,g, or c

<400> 259
gaggacgagg aggatgctca cgctggcatc attggccgct tcctaggcct gcagtcccat     60
gatcaccatc ctcccagggc aaactcaagg accaaactac tgtggcccaa gagggaatcc    120
cttctccacg agggcctgcc aawaaccaca aggcagccaa acagaacgtt aggggccagg    180
aagacaacaa ggcctggaag cttaaggctg tggacgcctt caagtctgcc ccactgtatc    240
agaggccagg ctactacagt gccccacaga crcccctcag ccccactccc atgttcttcc    300
ccctagaacc atcagcgccg tcaaagcttc acagtgtcac aggcatagac accaaagaca    360
aaagcttaaa gactgtgagt tctggggcca agaaaagttt tgaattgctc tcagagagcg    420
atggggcctt gatggagcac ccagaagtat ctcaagtgag gaggaaaacc gtggagttta    480
acctgacgga tatgccagag atccccgaaa atcacctcaa agaacctttg gaacaatcac    540
caaccaacat acacactaca ctcaaagatc acatggatcc ttattgggcc ttggaaaaca    600
ggtctgtcct ccacctgaac caggggcact gcattgccct gtgccccacc ccagcttccc    660
ttgctctgag cctacccttc ctccacaatt tcctagggtt ccatcactgc cagagcacac    720
tggacctacg cccagcactg gcttggggta tatacttggc caccttcaca gggatcctag    780
ggaagtgtcc gggacctttt ctcacttcac cctggtatca cccggaagac ttcttgggac    840
caggtgaagg aagatgaggt tgtgctgacc agaatgctgc tggagaactg ccccagggct    900
gacaggccag gcttagctga gcagatgtta tcactggccc caacttactt tgagcaaggg    960
tggctgaccc aaaaccatga ggtggcagtc agctggatga cagatgaaca cttcccccat   1020
aactatttag ggtagtaccc aagcactaca ggaaagggtg gcaggaactc tncactccta   1080
ggaactggta gatggtgagg ttgagggtgt ccagcgccct taggtcattt tctcactgcc   1140
tgggaacctc accaaaatac ttcttgcttc cttggggtca gcccaaagct gtcacaaaat   1200
cagatatttc cctttattcc agatttcctg gacactttca cccaattata aacaccccac   1260
ttcagcccca atcacgtggg aggaagtgta acttcccttt tctggattct caagcagtta   1320
ctttcacggt cagaacacgc agctattatg attgaaaact taaaagggca acaatttcag   1380
tcttgcttct agggctagac aggracttgg caaacatctg tggcctgttc agcaaaggat   1440
gttaatattt aagaatcttg tcttgggctg ggtgtggagg caagtggatc acaggaggtc   1500
aggagtttga gaccaacctg gccaacatga tgaaacccca tctctaccaa aaaaaataca   1560
aatcagctgg gcgtcgtggt gtgcctgtag tcccancgca ggaggttgag gggagaattg   1620
cttgaaccca ggangtggtg gttgcagtga gattgangca actgcaatcc agcctgggcg   1680
acgggagtga gactgtctca anaaaagaaa anaaaaa                            1717

<210> 260
<211> 1469
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (745)
<223> n equals a,t,g, or c

<400> 260
gctacaggga attggcttaa agggcaagtn ggttagtact tagctgtgtt tttattcaaa     60
gtctacattt tatgtagtgg ttaatgtttg ctgttcatta ggatggtttc acagttacca    120
tacaaatgta gaagcaacag gtccaaaaag tagggcatga ttttctccat gtaatccagg    180
gagaaaacaa gccatgacca ttgttggttg ggagactgaa ggtgattgaa ggttcaccat    240
catcctcacc aacttttggg scataattca cccaaccctt tggtggagcc tgaaaaaaat    300
ctgggcagaa tgtaggactt ctttattttg tttaaagggg taacacagag tgcccttatg    360
aaggagttgg agatcctgcm aggaagagaa ggagtgaagg agagatcaag agagagaaac    420
aatgaggaac atttcatttg acccaacatc ctttaggagc ataaatgttg acactaagtt    480
atcccttttg tgctaaaatg gacagtattg gcaaaatgat accacaactt cttattctct    540
ggctctatat tgctttggra acacttaaac atcaaatgga gttaaataca tatttgaaat    600
ttaggttagg aaatattggt gaggaggcct caaaaagggg gaaacatctt ttgtctggga    660
ggatattttc cattttgtgg atttccctga tctttttcta ccaccctgag gggtgttggg    720
ggaattatca ttttgctaca ttttnagagg tcatccagga tttttgaaac tttacattct    780
ttacggttaa gcaagatgta cagctcagtc aaagacacta aattcttctt agaaaaatag    840
tgctaaggag tatagcagat gacctatatg tgtgttggct gggagaatat catcttaaag    900
tgagagtrat gttgtggaga cagttgaaat gtcaatgcta gagcctctgt ggtgtgaatg    960
ggcacgttag gttgttgcat tagaaagtga ctgtttctga cagaaatttg tagctttgtg   1020
caaactcacc caccatctac ctcaataaaa tatagagaaa agaaaaatag agcagtttga   1080
gttctatgag gtatgcaggc ccagagagac ataagtatgt tcctttagtc ttgcttcctg   1140
tgtgccacac tgcccctcca caaccatagc tgggggcaat tgtttaaagt cattttgttc   1200
ccgactagct gccttgcaca ttatcttcat tttcctggaa tttgatacag agagcaattt   1260
atagccaatt gatagcttat gctgtttcaa tgtaaattcg tggtaaataa cttaggaact   1320
gcctcttctt tttctttgaa aacctactta taactgttgc taataagaat gtgtattgtt   1380
caggacaact tgtctccata cagttgggtt staaccctca tgcttggccc aamyaaactc   1440
tctacttata aaaaaaaaaa aaaaaaacc                                     1469

<210> 261
<211> 734
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (67)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<400> 261
aagctggtca atgtcaccat ccacttccgg ctgaagacca ttaacctcca gagcctcatc     60
aataatnaga tcccggactg ctataccttc agcgtcctga tcacgtttgg acaacaaagc    120
acacagtggg cgggatcccc atcagcacgg agaacaacag cttccggctc ctgtttgacg    180
tggtggtcat cctcacctgc tccctgtcct tcctcctctg cgcccgctca ctccttcgcg    240
gcttcctgct gcagaacgag tttgtggggt tcatgtggcg gcagcgggga cgggtcatca    300
gcctgtggga gcggctggaa tttgtcaatg gctggtacat cctgctcgtc accagcgatg    360
tgctcaccat ctcgggcacc atcatgaaga tcggcatcga ggccaagaac ttggcgagct    420
acgacgtctg cagcatcctc ctgggcacct cgacgctgct ggtgtgggtg ggcgtgatcc    480
gctacctgac cttcttccac aactacaata tcctcatcgc cacactgcgg gtggccctgc    540
ccagcgtcat gcgcttctgc tgctgcgtgg ctgtcatcta mctgggstac tgcttctgtg    600
gctggatcgt gctggggscc tatcatgtka agcctcttca tctacatggt gctcarccty    660
ttcatcgcgs tcatcaccgg sgsctacgac accatcaagc atcccggcgg cgcaggngca    720
gaggagagcg agct                                                      734

<210> 262
<211> 594
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (570)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (572)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (584)
<223> n equals a,t,g, or c

<400> 262
ggcacgagca aattttcttt ttaatactgg aaagtttatt tttaatttta ttcatcacat     60
taatgacaca gacactatac tgagtaccaa taatagcaac cctgtgattt gtccaagtgc    120
cgggagtgga ggccatcctg acaacagctc tatgattttc tatgccaatg acacaggagc    180
ccaacagttt gaaaagtggt gggataagtc caggacagtc cccttttatc ttgtagggct    240
cctcctccca ctgctcaatt tcaagtctcc ttcatttttt tcaaaattta wtatcctagg    300
cacagtgtct gtccytkatt tgattttcct tgtcaccttt aaggctgttc gcttgggatt    360
tcatttggaa tttcattggt ttataccaac agaatttttt gtaccagaga taagatttca    420
gtttccacag ctgactggag tgcttaccct tgcttttttt attcataatt gtatcatcac    480
actcttggaa gaacaacaag aaacaaggaa aacaatgtgg aggggacttg tggcattggc    540
ttatatgctg gtggacatta acttaacccn anattgggag tccngggttt tggc          594

<210> 263
<211> 715
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (627)
<223> n equals a,t,g, or c

<400> 263
ggcagagcgg gtttcgttgt gtttcgcgcc atgtcgtttg ctgagagcgg gtggcggtcg     60
gctctgcggc gccgcggtcc cggcaccccg ggccctgtgg ctcggccatc gtattcctcc    120
tttactcagg gggacagctg gggtgaaggc gaagtcgacg aggaggaggg atgcgaccaa    180
gtggcccgcg acctgcgggc ggagttctcg gctggggcgt ggtcagagcc cagaaagcgc    240
tcggtgctcc cgccggacgg gaacgggtcg cccgttctgc ccgataagcg caatggtatc    300
tttcccgcgg ccgcgggcag cagagcccag cctcggcggt ggccggtcca ggtcctctct    360
attctctgct cgctgctctt cgccattctt ctcgccttcc tcctcgcatc gctacttgat    420
cgttaaaggt attgaagccg acgccttgaa agtctgtcca gagtaaagtt gagccagggt    480
gtggctctcg tctccaccca tctccctttc cctcgcgcta agccctcagg ctggcagctg    540
ctttcaccca gagtcctcat ttgcatctta ctttgctctc ccgccctttg ccttttctaa    600
gtggagcgtc ctgatccatg atcaggngac gtatttttaa aaaggatcgt ttgattaaat    660
gggtactctt gaagaaatat cttcaagtcc ttgaacactg gggatgaaat attgt         715

<210> 264
<211> 2013
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> n equals a,t,g, or c

<400> 264
ggtcacgagg cacttttggt aagccaggga tcgtgtgggt ggtacggagt tgccacattt     60
cggcaaaggn aactatgtag ctgatcttgg agccatggtg gtaacaggtc tttgagggaa    120
tcctatggct gtggtcagca aacaagtaaa tatggaactg gccaagatca agcaaaaatg    180
cccactttat gaagccaacg gacaagctgt tcctaaagag aaagatgaaa tggtagagca    240
agagtttaac cggttgctag aagctacatc ttaccttagt catcaactag acttcaatgt    300
cctcaataat aagcctgtgt cccttggcca ggcattggaa gttgtcattc agttacaaga    360
gaagcatgtc aaagatgagc agattgaaca ttggaagaag atagtgaaaa ctcaggaaga    420
attgaaagaa cttcttaata agatggtaaa tttgaaagag aaaattaaag aactccatca    480
gcaatacaaa gaagcatctg aagtaaagcc acccagagat attactgccg agttcttagt    540
gaaaagcaaa cacagggatc tgaccgccct atgcaaggaa tatgatgaat tagctgaaac    600
acaaggaaag ctagaagaaa aacttcagga gttggaagcg aatcccccaa gtgatgtata    660
tctctcatca agagacagac aaatacttga ttggcatttt gcaaatcttg aatttgctaa    720
tgccacacct ctctcaactc tctcccttaa gcactgggat caggatgatg actttgagtt    780
cactggcagc cacctgacag taaggaatgg ctactcgtgt gtgcctgtgg ctttagcaga    840
aggcctagac attaaactga atacagcagt gcgacaggtt cgctacacgg cttcaggatg    900
tgaagtgata gctgtgaata cccgctccac gagtcaaacc tttatttata aatgcgacgc    960
agttctctgt acccttcccc tgggtgtgct gaagcagcag ccaccagccg ttcagtttgt   1020
gccacctctc cctgagtgga aaacatctgc agtccaaagg atgggatttg gcaaccttaa   1080
caaggtggtg ttgtgttttg atcgggtgtt ctgggatcca agtgtcaatt tgttcgggca   1140
tgttggcagt acgactgcca gcaggggtga gctcttcctc ttctggaacc tctataaagc   1200
tccaatactg ttggcactag tggcaggaga agctgctggt atcatggaaa acataagtga   1260
cgatgtgatt gttggccgat gcctggccat tctcaaaggg atttttggta gcagtgcagt   1320
acctcagccc aaagaaactg tggtgtctcg ttggcgtgct gatccctggg ctcggggctc   1380
ttattcctat gttgctgcag gatcatctgg aaatgactat gatttaatgg ctcagccaat   1440
cactcctggc ccctcgattc caggtgcccc acagccgatt ccacgactct tctttgcggg   1500
agaacatacg atccgtaact acccagccac agtgcatggt gctctgctga gtgggctgcg   1560
agaagcggga agaattgcag accagttttt gggggccatg tatacgctgc ctcgccaggc   1620
cacaccaggt gttcctgcac agcagtcccc aagcatgtga gacagatgca ttctaaggga   1680
agaggcccat gtgcctgttt ctgccatgta aggaaggctc ttctagcaat actagatccc   1740
actgagaaaa tccaccctgg catctgggct cctgatcagc tgatggagct cctgatttga   1800
caaaggagct tgcctccttt gaatgaccta gagcacaggg aggaacttgt ccattagttt   1860
ggaattgtgt tcttcgtaaa gactgaggca agcaagtgct gtgaaataac atcatcttag   1920
tcccttggtg tgtggggttt gttttttttt tttatatttt gagaataaaa cttcatataa   1980
aattgaaaaa aaaaaaaaaa aaaaaaaaaa ctc                                2013

<210> 265
<211> 947
<212> DNA
<213> Homo sapiens

<400> 265
ggcagaggtt tctggagtgc accctgatcc tcacctcggt cgtgcctcct gagctgccca     60
tcgagctgtc cctggccgtc aacacctccc tcatcgccct ggccaagctc tacctggagg    120
gagtcaagtt cagtgacttc caggccaccc tacaggggct gctgctggcc ggctgcttcc    180
tcttcatctc ccgttccaag cccctcaaga ccctctcccg agaacggccc ctgcccaaca    240
tcttcaacct gtacaccatc ctcaccgtca tgctccagtt ctttgtgcac ttcctgagcc    300
ttgtctacct gtaccgtgag gcccaggccc ggagccccga gaagcaggag cagttcgtgg    360
acttgtacaa ggagtttgag ccaagcctgg tcaacagcac cgtctacatc atggccatgg    420
ccatgcagat ggccaccttc gccatcaatt acaaaggccc gcccttcatg gagagcctgc    480
ccgagaacaa gcccctggtg tggagtctgg cagtttcact cctggccatc attggcctgc    540
tcctcggctc ctcgcccgac ttcaacagcc agtttggcct cgtggacatc cctgtggagt    600
tcaagctggt cattgcccag gtcctgctcc tggacttctg cctggcgctc ctggccgacc    660
gcgtcctgca gttcttcctg gggaccccga agctgaaagt gccttcctga gatggcagtg    720
ctggtaccca ctgcccaccc tggctgccgc tgggcgggaa ccccaacagg gccccgggag    780
ggaaccctgc ccccaacccc ccacagcaag gctgtacagt ctcgcccttg gaagactgag    840
ctgggacccc cacagccatc cgctggcttg gccagcagaa ccagccccaa gccagcacct    900
ttggtaaata aagcagcatc tgagatttta aaaaaaaaaa aaaaaaa                  947

<210> 266
<211> 716
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (89)
<223> n equals a,t,g, or c

<400> 266
ggggggaaaa aggnaagccn ctgtcctgnt cttacccagc tctatgatca ttagaatgac     60
agctgtgaat acacaaagtg taaaccttnt tgtcagccct gactgtctga agtatcaggt    120
tcctccacac acgtctgggc cccagcagca aaagaaggcc actgggtaga agcgcacccg    180
ttggtccaca atgtgaatca ctgcccactg ttcactcccc agaaagccag ttgacttcac    240
aaacttctta tacaatgtct gggctcggat aagtaagact tgtggctctg actgaagttt    300
tggaaacatt cactagtatt tcccagacag aatacaggtg tcatcaatag cagaggtatc    360
aggcttgaga aaacaaagsc catttgacma actcgacaag tataatctat caccagtgga    420
gatgtgctct gtccactctg ggtgtgtttc atcctcagct ctgtgtacaa ataccagatg    480
taattgacgg tgtagagaaa tgaggaaatg tagaatatct ctttcacttg gcagaacatt    540
ggtgtaatta aaatttcaca atcagtagcc actgcagata acttgacaag atctagaatt    600
ctgtttccag tatccagtaa aattattcag acaccagatc tgctgattat cttaatcttg    660
gaccttccag cctccagaac tgtccaactg cttgtaggtt atagcagatg atgtcc        716

<210> 267
<211> 612
<212> DNA
<213> Homo sapiens

<400> 267
gtgaccgccc agagcgcggt gaggagcgcg ggggcgcggg gcgggaggcc cagctgagcc     60
ggccgtcgga gtgagaccct gcggcagaga cgacggaggg gaagaacccg atcccggagc    120
ggcggcggcg gggggagccg gagccgctgg gatgttcagt catgaaacga gtgcgtaccg    180
agcagattca gatggcagtg tcctgctacc tcaaacgccg gcagtacgtg gactcagatg    240
gtcccctgaa gcaaggactg cggctgtcac agactgctga agagatggcg gccaatctaa    300
cagtgcaatc agaatctggt tgtgccaaca tagtgtctgc agccccttgc caggcagaac    360
cccagcaata tgaagtacag tttggacgac tgcggaattt tctcactgat tctgattccc    420
agcatagcca cgaagtgatg cctctcctct atcctctctt tgtctacctc catctcaacc    480
tggtccaaaa cagtccgaag agcacagtgg aaagttttta cagccgcttc catggaatgt    540
ttctgcagaa tgctagccag aaggatgtca ttgagcagct acagacactc aaacatccag    600
acatctatct at                                                        612

<210> 268
<211> 631
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (526)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (548)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (605)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (612)
<223> n equals a,t,g, or c

<400> 268
ggcaacacag catccggggc tcctcacaag gtgaagaaac ataagcagtt aatgctagaa     60
tctatcatca gaggcctgta tcacctagct cgcactgaag tcgtctgtga aagcttgaag    120
gctctaaaaa aaatcctgga gctgctgaca gaccgagacg tgagcttcta cttcaaggaa    180
atagtgctgc aaacaaggac cttctttgaa gatgagcagg atgatgtgag attgactgcc    240
atcttcttat ttgaggacct ggcaccccta acaggaagaa ggtggaagat tttttttgct    300
gaagaaataa aaaagagcct gatttcattc cttctgcacc tttgggatcc caaccccaag    360
attggagttg cttgccgtga tgtcttgatg gtctgcattc cctttttggg cctccaggag    420
ctctatgggg tattagaccg tctccttgat caggatctac caagggccag ggatttctat    480
aggcaattct gtgtgaaact ggccaagaaa aaccaggaaa ttctgnggat cttcacacac    540
acttcttnac cttcttcacc aagcaccctg ggaaggggat cagganttgc aagttgtcaa    600
aactncagaa tnccgttgtt cttaaatttg a                                   631

<210> 269
<211> 807
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (738)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (770)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (778)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (801)
<223> n equals a,t,g, or c

<400> 269
gcagagggat cttgccctca ttctttgggt ctgaaacact ggcagtcgtt ggaaacagga     60
ctcagggata aaccagcgca atggattggg ggacgctgca cactttcatc gggggtgtca    120
acaaacactc caccagcatc gggaaggtgt ggatcacagt catctttatt ttccgagtca    180
tgatcctcgt ggtggctgcc caggaagtgt ggggtgacga gcaagaggac ttcgtctgca    240
acacactgca accgggatgc aaaaatgtgt gctatgacca ctttttcccg gtgtcccaca    300
tccggctgtg ggccctccag ctgatcttcg tctccacccc agcgctgctg gtggccatgc    360
atgtggccta ctacaggcac gaaaccactc gcaagttcag gcgaggagag aagaggaatg    420
atttcaaaga catagaggac ataaaaagca gaaggttcgg atagaggggt cgctgtggtg    480
gacgtacacc agcagcatct ttttccgawt catctttgaa gcagccttta wgtatgtgtt    540
ttacttcctt tacaatgggt accacctgcc ctgggtgttg aaatgtggga ttgacccctg    600
ccccaacctt gttgactgct ttatttctag gccaacagag aagaccgtgt ttaccatttt    660
tatgatttct gcgtctgtga tttgcatgct gcttaacgtg gcagagttgt gctacctgct    720
gctgaaagtg tgttttanga gatcaaagag agcacagacg caaaaaaatn accccatnat    780
gccctaaagg agagtaagca naatgaa                                        807

<210> 270
<211> 686
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (655)
<223> n equals a,t,g, or c

<400> 270
ggaggttctc aagcagttac cccccaagaa agatcgaatt gagttgtgtg cartgtcgga     60
gaagcaggag caactctatt tgggtctttt caacagattg aaaaaatcta tcaataactt    120
ggtcacagaa aaaaacacag aaatgtgcaa tgtcatgatg cagttgagga aaatggccaa    180
tcatccttta ttacatcgcc aatattacac agctgaaaaa ctcaaggaaa tgtctcagct    240
tatgctaaag gaacctacac attgtgaggc taaccctgac ctgatctttg aagatatgga    300
agttatgaca gacttcgaac tacatgtact ttgtaaacag taccgacaca ttaataactt    360
tcagttagac atggacttga ttttagattc tggaaaattt cgagttttag gatgcatctt    420
gtctgaattg aaacagaagg gtgatagagt tgtgttattt agccaattta ccatgrtgct    480
ggrtatctta gaggttctat taaaacatca tcagcatagg taccycagrt tagatggraa    540
gactcagrtt tctgaaggga ttcmtctaat tgatgagttt aataccgata trtatctttg    600
gtttctgcta tcacaaaagc tggtggatta ggaattaaat ctggacttca gcaangttgt    660
tatacttcac ggtattggac tgtaat                                         686

<210> 271
<211> 532
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (255)
<223> n equals a,t,g, or c

<400> 271
gggagatcac ttcccgcctc ctgattctgg tgctcttctc agccactttg aaattgaagg     60
ctgtgccctt cctagtgctc aacttcctga tcatcctctt tgagccctgg attaagttct    120
ggagaagtgg tgcccagatg cccaataaca ttgagaaaaa cttcagccgg gtcggcactc    180
tggtggtcct gatttcagtc accatcctct atgctggcat caacttctct tgctggtcag    240
ctttgcagtt gaggntggca gacagagatc tcgtcgacaa agggcagaac tggggacata    300
tgggcctgca ctatagtgtg aagttggtag agaatgtgat catggtcttg gtttttaagt    360
tctwtggagt gaaagtgkta ctgaattact gtcatycctt gawtgccttg cagctcatta    420
ttgcttatct gatttccatt ggcttcatgc tccttttctt ccagtacttg catccattgc    480
gctcactctt cacccataat gtagtagact acctccattg tgtctgctgt ca            532

<210> 272
<211> 567
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (273)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (499)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<400> 272
gggagcccac cntagccggg cggctgggat gatgaaccgg acgacccccg accaggagct     60
ggtgccggcg tcggagcccg tgtgggagcg gccgtggtcg gtggakgaga tccgcaggag    120
cagccagagc tggtcgctgg cggccgacgc gggcctacta cagtttctac aggaattctc    180
acagcaaact atctctagga cccatgaaat caagaaacaa gtggacggac taatccggga    240
aaccaaagcc acagattgtc gcctgcataa tgncttcaat gacttcctta tgctctctaa    300
tacccagttc atagagaatg tgagttattt aagttatatt ataattcctt ttttgggagt    360
aggagatatt gtaattttaa ataacttact gttaggttcc ctcctaaatt ttggtggaag    420
tgtggttctt ggtaattgta gcttttttct ctgggattaa cgcctctttt ttatttgtaa    480
agttttaagt ccttttttnc aagcctctaa aaaagtctaa tgataaaaat tttcttatac    540
ttcagtgctt ncatcttttg cggtttg                                        567

<210> 273
<211> 1219
<212> DNA
<213> Homo sapiens

<400> 273
aattcggctt tcgagcggcc gcccgggcag gtacttgctt tgccgtgcca cataaccata     60
ggtcacccac ctctagttct acaggaatcc atcatctctg ttggaataac tcaaaataca    120
ggctcttgat ggtaggttaa aaacatggtc ctgttatgtg atagataaca caatactgtg    180
ttttgaagtt aagtcgaaaa ttgtaggggt tatcagtaac ctagaaaaga aaacagcttg    240
tccatgtaga aagattagag gatctaaatt aaattggaaa ttgtcctatt gcatcaatct    300
tctccctaac tttatcaata aagacctgat ttccctcact ttattctgga aactgatatt    360
gtaacacatg aaatccatag gttgtataga atgagggtaa cagaactttt atgttatctg    420
tttgaaagaa tgaaaggagc actgtaatcc tgaattcaaa ttggagtctt gtaaacaact    480
aaataatagt atgtgatact atggaaatat aatatatgac ccggaaggat taaagaagtt    540
gtcattagaa tatgtgggat ttatgttaca cataaataag cagtcatcta agaggactaa    600
catggagttt ttcacaaaat gaaaaagaaa gaaacaaagg gttgaatagt acaatgaaga    660
ctgtattaca ttcagacaat aaggaattgt ctttttattt gcagggcaaa acaaaatctt    720
tatctgtggt gatagaaagt tcagggtaat atatatggaa gcatgaaatg aaaaattgtg    780
gaacaaacta tctaagaata taaatatagt ctctcttttc ataaatattc aatacgttat    840
ttgacacatt ggtttgagts aagctccaca agtacaattt taagcatctt gatttgggct    900
gaggtccagt aaattatata ttcccaacaa ctatcagagc tctcccacta aaaatacatg    960
ctcacgctct actttgaaaa tattctaaga taattatttc cattttcata gtaactagta   1020
cagttatgac tagcattctc tcaggtttct aaggaaagaa aattattctg agatactgtt   1080
aataagagaa aatgtggtaa tagagagggg cattttctta aaattgtgct aaagctgtca   1140
tttttatttt taatgacttt aactgtgcta gacaagattt tattttcagc cacagaaata   1200
aaactatcca acataactc                                                1219

<210> 274
<211> 765
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (448)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (451)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (635)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (733)
<223> n equals a,t,g, or c

<400> 274
ggaacaaagg ccggacctcc aangcggtgg cggccgctct aaaactagtg gatccccctt     60
tcaaccccat cgggtcctga gtaatatacc gcccctgcaa cggatcgtag taccggtgac    120
ggttatagta cagccctgat tcctcatcat gctgctgccc tggcagacgg tacggctgat    180
acacatgatg cgggttctcc tcattaagct ggttgcccca ttcatcatat tccgcgctcc    240
acgccgtatt gccgtcttcg ctgataagcg ccagcggcag tccccggtgg tcgcagtgat    300
aaagatgarc ttttcgcgcc ggtgtgtatt ccggctccac ctgtctggcc agttgctcca    360
ccgtcagccc gcactgcgca agccacgccc ggctttcact gctcacgcgg tctgcccgga    420
tttcttcctc cagcctgtcc agcagccnca ncagttcagc cgggaacacc acgccgtggc    480
cgttctcact cccttcctgc tggagcgtct ctgccaagct gcgccgctgc gctttttccc    540
gctcgccgtt ctctgtctcg accggatgaa cggcgtgaac ttcccngctc gtataccgtc    600
tggatactgt ggtgtcagtc tgcaccgtct tcagnctgtc tccgtccatc cataccacgt    660
cactccggtt taccgaaaac gaaatccacc ccgtcaggtc acgctcccgc cgccaaaacc    720
gttttgccat tcncctccca accgggtctt aaaaggttcc ggtct                    765

<210> 275
<211> 522
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (514)
<223> n equals a,t,g, or c

<400> 275
caccacgtgg ctgtgaaaat gacaaagcat ggtcgtgagc cactatgccc ggccggattt     60
gcccttatta atggttattt cttgtgaaag tttctttttg cctttgcatt ccttttattc    120
tgtttattcc cccatgcctc acccaaagag ttgcacggtc aattggcccg tgaaggggac    180
gcctactttc aaacaaggca gacaggacac gacaggacgg cggctcatag cacagacttt    240
ggattgcagt ggatgggacc agatcctggc tccacttcts gcyagctgtg tggccctggg    300
caagctgctt aacctctctg ggcctcagtt tctccccctg taaactgggg gatgtgaaca    360
gcgcctgcct ccgagtccta aggattggga gtagtcgtgt aaagtgctca ggtccacagg    420
ccatcaatac taatagttaa aaattattct tagaatcttg cttccctcag ctccctgaaa    480
ggccactaag gcaccccagt tgcagaggcc aatnggtccg gg                       522

<210> 276
<211> 746
<212> DNA
<213> Homo sapiens

<400> 276
cccaagcact cctttttctc tgcatgatac ttctgcttat tgtccttcac actagctaca     60
tgatttatag tcttgctccc caatatgtta tgtatggaag ccaaaattac ttaatagaga    120
ctaatataac ttctgataat cataaaggca attcaaccct ttctgtgcca aagagatgtg    180
atgcagawgc tcctgaagat cagtgtactg ttacccggac atacctattc cttcacaagt    240
tctggttctt cagtgctgct tactattttg gtaactgggc ctttcttggg gtatttttga    300
ttggattaat tgtatcctgt tgtaaaggga agaaatcggt tattgaagga gtagatgaag    360
attcagacat aagtgatgat gagccctctg tctattctgc ttgacagcct tctgtcttaa    420
aggttttata atgctgactg aatatctgtt atgcattttt aaagtattaa actaacatta    480
ggatttgcta actagctttc atcaaaaatg ggagcatggc tataagacaa ctatatttta    540
ttatatgttt tctgaagtaa cattgtatca tagattaaca ttttaaatta ccataatcat    600
gctatgtaaa tataagacta ctggctttgt gagggaatgt ttgtgcaaaa ttttttcctc    660
taatgtataa tagtgttaaa ttgattaaaa atcttccaga attaaaaaaa aaaaaaaaaa    720
aaaaaaaaaa aaaaaagggc ggccgc                                         746

<210> 277
<211> 612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<400> 277
ccgggaacct ggcgccgccg gaactgatcg cggcctagtc ccgacgcgtg tgtgctagtg     60
agccggagcc ggcgacggcg gncagtggcg gcccggcctg caggagcccg acggggtctc    120
tgccatgggg gagtgacgcg cctgcacccg ctgttccgcg gcagcggcga agacatgagg    180
agaccccgcg acaggggcag cggcggcggc tcgtgagccc cgggatggag gagaaatacg    240
gcggggacgt gctggccggc cccggcggcg gcggcggcct tgggccggtg gacgtaccca    300
gcgctcgatt aacaaaatat attgtgttac tatgtttcac taaatttttg aaggctgtgg    360
gacttttcga atcatatgat ctcctaaaag ctgttcacat tgttcagttc atttttatat    420
taaaacttgg gactgcattt tttatggttt tgtttcaaaa gccattttct tctgggaaaa    480
ctattaccaa acaccagata attggttcac taaaaattcc tggtagaaaa gaatttaang    540
acaaaaagtt aaatgatcct aggaaactag tgggaaactg agaaatcata aaattgtact    600
ctgaagaaaa ag                                                        612

<210> 278
<211> 903
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (839)
<223> n equals a,t,g, or c

<400> 278
ggaggtagca aacagccttg ccaaactgag tgtccatgct ctgagtcgcc ttggagggta     60
tttggctgaa gaacaagcaa ctccagaaaa tccaaccata aggaaaagct tagctggcat    120
gctgacaccc tatgttgcta gaaaacttgc tgtggctagt gtgactgaga ttttgaagat    180
gcttaacagc aacacagaaa gtccatattt gatatggaac aattctacaa gagcagaatt    240
acttgaattt cttgaatccc aacaagaaaa catgattaaa aaaggtgatt gtgacaaaac    300
ttatggatca gaatttgtct acagtgatca tgccaaagaa cttattgtag gggagatttt    360
tgttagggtg tataatgaag ttcctacttt ccaactggag gttccaaaag catttgctgc    420
aagtctcttg gattatatag gctcgcakgc ccaatacttg cacacattca tggccatcac    480
acacgcggca aaagtggagt cagagcaaca tggagatcgc ttaccgagag tagaaatggc    540
tttggaggct ctgagaaatg tcataaaata caatccaggt tctgagagtg aatgcattgg    600
gcactttaag ttgatatttt ctcttctccg agttcatgga gctggtcaag tgcagcagtt    660
ggctttagag gttgtgaata tagtgacatc taaccaagac tgtgtcaaca atattgctga    720
atcaatgggt tttgtccagt ttattggctc ttctacattc attgccatca agtcggtcag    780
cttggttctg ggaaactctt tatgctttgg acatccgagt acaaaaatta atcaaagang    840
caatggcaaa gggtgctttg attccattta ctggatatgt tctgcaattc aacacatcca    900
cag                                                                  903

<210> 279
<211> 609
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (517)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (522)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (553)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (562)
<223> n equals a,t,g, or c

<400> 279
gcggaaggag cccccasgaa gccctgtaga tgcccccacc ccagcccatg gagttgctat     60
ggttaagcag cctgagccgt acagttgaaa aggggcggtg gggcccatct ccaaatagca    120
cagccagttc agccgtctgt cctcaaccca ggagagctgg gaaagccagt ggactcctgc    180
acctggttct tgtcactcct ggcgtttgtg tacagatcac cacttctctt tttggttcat    240
tgttgaggag tcgttttccg gacggctcca tcacagcatt gagctatcaa gctgctgttt    300
tccacagttg gtggtcacag ccagggaagt tgctgtcttg atttgttaca ttgtcagtaa    360
tccccaagga accaatggat gtcagtagga gtttctgtta aatgtctcct tgatggggac    420
tcagtactgt gtagagacgc tgtgtttctc ttctgggggt gtggcattca gaaaccactg    480
ggggcctttt taaaatctaa cagatgccgg cccgggncgc cntgggcttc acgcctggga    540
aattcccagg canttggggg anggctgaag cgggcggatt caacaagcgc aaggaaattt    600
gagaaccat                                                            609

<210> 280
<211> 1099
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1011)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1086)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1090)
<223> n equals a,t,g, or c

<400> 280
cactattgta ctggagctta tcggatttca cctgtagatg taaatagtag accttcctcc     60
tgccttacta attttcttct aaatggtcgt tctgttttat tggaacaacc acgaaagtca    120
ggttctaaag tcattagtca tatgcttagt agccatggag gagagatttt tttgcacgtc    180
cttagcagtt ctcgatccat tctagaagat ccaccatcaa ttagtgaagg atgtggagga    240
agagttacag actaccggat tacaacccca gatataaaat cgatggaagt cttgaggtcc    300
ctttggaacg agcaaaagat cagttagaaa aacatacccg ttactggcct atgatcattt    360
cacaaaccac catttttaac atgcaagcgg tagttccatt agccagtgtt attgtgaaag    420
awtctctgac agaagaagat gtgttaaact gtcaaaaaac aatatacaac ttagttgata    480
tggaaagaaa aaatgatcct ctacctattt ccacagttgg tacaagagga aagggcccta    540
aaagagatga acaataccgt atcatgtgga atgaattaga aacccttgtc agagcccata    600
tcaacaactc agagaaacat caaagagtct tggaatgtct gatggcatgc aggagcaaac    660
ccccagaaga ggaagaacga aagaaacgag gaagaaagag ggaagacaaa gaggacaagt    720
cagagaaagc agtgaaagat tatgaacagg aaaagtcttg gcaagactca gagagattaa    780
aaggaatctt agagcgtgga aaagaagaat tggctgaagc tgagattata aaagattcgc    840
ctgattcccc agaacctcca aacaaaaaac cccttgttga aatggrtgaa actccacaag    900
tggaaaaatc aaaagggcca gtgtcgttat tatccttgtg gagtaataga tcaatactgc    960
caattccaga aaacatcagg gatttgctgg acgttttgaa ctctgttaat naacagrgct   1020
tgaactwtat ccaacatctt taaaggggga aattggggtt tggggaccac cggaaattgg   1080
gaaagnccan ccggcagtt                                                1099

<210> 281
<211> 1013
<212> DNA
<213> Homo sapiens

<400> 281
tgaatcagtc acctgtgctt gcttaaaaag tttcttgaag actgtcatca ccaatgctca     60
agaaacagat gttaatatgg agtcagtttt tgactatagt ataaattctg tacatgatga    120
gaaaatggaa gagcaaactg aaattcttca aaatggcttc aatcctgaag aagataaatg    180
caataactgt gatcaagagt taaataaaaa gccccaggac gaaacaaagg agagcacttc    240
atgccctgtg gtacaaaaaa gagcagctct acttaatgca attcttcatt cagcatatag    300
cgagacattt cttctgcctc atttgaaaga catcccagca cagcatatca cgctgtttct    360
taagtatttg tatttcctgt acctgaagtg tagcgaaaat gctactatga ctcttcctgg    420
aatacaccca cctaccttga accagattat ggattggata tgtctacttc tggatgcaaa    480
ttttactgtt gttgtaatga tgccagaagc aaagaggcta ctgataaatc tttacaagct    540
tgtaaaatct cagatatctg tttattctga gctcaacaag attgaagtaa gttttcggga    600
gctacagaaa ttaaatcaag aaaagaataa tagaggatta tattcaattg aagtgctgga    660
gctcttctga tattatcaat tctccttcat agacatttta taaagctctt ttatgtgaac    720
tcttgcttca tccaggcaag aacggtgttt tgtttgcgac catctcagtg tcaagagaaa    780
cgtgtcagtg agtacctgga ccatcactta actgatgctc cggggtagga ctgcaggttt    840
cacatgaacc tgttctaggc tgtggacatt ggtgtggaga ggttctgcaa ttttttaaaa    900
atatgtaact gggttgattt taagtaaaat tatttgtgta ttgataaaag tctaatttct    960
tatcatgtgt tttgaatttt ttcttttaat aaaaaatgac cattgaagca gtg          1013

<210> 282
<211> 1197
<212> DNA
<213> Homo sapiens

<400> 282
ggcacgagag gaagtccact agcagcttct aaggaatgcc tctctgtatg gaacataaaa     60
tttcaaacac tacagacttc aaaagagtta ccacaaggga ccagtggtca actctggtat    120
tatggagaac atttgtttat gctacatgga aaatctctaa ctgtgattcc atacaagtgt    180
gaagtgtcat cattagcagg tgctcttgga aaactcaagc atagtcaaga tccaggaact    240
catgtcgtgt cccattttgt aaactgggag acacctcaag gatgtggact tgggttccag    300
aactcagagc agtcaagaag aattttaagg agacgaaaaa ttgaagtgag tttacagcca    360
gaggttccac catccaaaca acttttgtca accataatga aagattcaga aaaacacatt    420
gaagtagaag tacggaaatt tttggctctg aagcagacac ctgactttca tactgtcatt    480
ggggacacag taacaggact tctggaaagg tgtaaagcag aaccatcatt ttatccccgg    540
aactgtctga tgcagcttat ccraacgcat gtgctttctt acagtttgtg ccccgactta    600
atggagattg ccttaaaaaa gaaagatgta cagttgttac aactctgtct acagcagttc    660
cctgacattc ctgaatcagt cacctgtgct tgcttaaaaa ttttcttgag cattggtgat    720
gacagtcttc aagaaacaga tgttaatatg gagtcagttt ttgactatag tataaattct    780
gtacatgatg agaaaatgga agagcaaact gaaattcttc aaaatggctt caatcctgaa    840
gaagataaat gcaataactg tgatcaagag ttaaataaaa agccccagga cgaaacaaag    900
gagagcactt catgccctgt ggtacaaaaa agagcagctc tacttaatgc aattcttcat    960
tcagcatata gcgagacatt tcttctgcct catttgaaag acatcccagc acagcatatc   1020
acgctgtttc ttaagtattt gtatttcctg tacctgaagt catccttgat tcttctttta   1080
gcacccatat ccaatccatt agcaaatctg gtagacccta ccttcacaat atatctaaag   1140
ctgaccacct ctttttgacc tctactatta acggcctatt ccaaggcacc atcatct      1197

<210> 283
<211> 555
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (458)
<223> n equals a,t,g, or c

<400> 283
agaccgtaaa acactggcac accacatagg gcacttgtgg tgggcagcag atgaaaacaa     60
tttcagtcgt tggaatagag ctgtgccccc ctggaaaacg gttcatgatt acgatggtgg    120
cgagcttcgt ggccatggcg ggccagttcc tcatgcctgg gctagccgcc ctgtgccggg    180
attggcaggt gctgcaggcc ctcatcatct gccccttcct gctcatgctg ctctactggt    240
cgatattccc cgagtccctc cggtggctaa tggccaccca gcagtttgag tctgcaaaga    300
ggctgatcct ccacttcaca cagaagaatc gcatgaaccc tgagggcgac atcaagggtg    360
tgataccaga gctggagaaa gagctttccc ggaggcccaa gaagtctgca tcgtgaaggt    420
ggtggggaca cggaamctgt ggaagaacat tgtggtcntg tgtgtgaact cgctgacggg    480
gtacgggatc caccactgct ttgccaggag catgatgggc cacgaggtga aagtgccgct    540
tcctggagaa cttct                                                     555

<210> 284
<211> 1518
<212> DNA
<213> Homo sapiens

<400> 284
agcggcgctg gaggagcwcg aggctgaggc tgccgggggg ctgtgggcta ccgggccgcc     60
ggcgcctcag cgatgtttta ctcagggctc ctcactgagg gcggccgcaa ggagaccgac    120
atgcgggagg cggcgtcact gcgacagcag cgccggatga agcaggcggt gcagttcatc    180
cacaaggact ccgccgacct gctgcccctg gacggcctca agaagctggg ctcgtccaag    240
gacatgcaac ctcataatat tctgcagagg cgcctcatgg aaaccaacct gtctaagctc    300
cgaagcggtc cccgtgtccc ttgggcctct aagacgaaca aactcaatca ggctaagtct    360
gaggggctaa agaagtctga ggaggatgac atgattttgg tttcttgcca gtgtgctgga    420
aaggatgtga aagccttggt tgacacaggc tgcctatata atctcatctc tttggcctgt    480
gtggacagat tgggactcaa ggrgcatgtc aaatcccaca agcatgaagg agaaaagctt    540
tctctacccc ggcatctcaa agtagtgggc cagattgagc acctagtgat cacactgggc    600
tccctccgcc tggactgccc agcagctgtg gttgatgaca atgagaaaaa cttgtccctt    660
ggtctacaga ctctccgatc tctgaagtgc atcataaact tggataagca ccggctgatc    720
atggggaaga cagacaagga agaaatccct tttgtggaga cagtctcttt gaatgaagac    780
aacacttcag aagcataact acagcctgca gcatgtctgc acgtgtgcat ggcatacaca    840
ccgggttgac agattgwgaa aactgggttt gaaccaaatg ccgtagtgac ttgctgtgga    900
ccaagtcctt ccatctaata gaagctccag gggctccttc ccattcagac ctctctagac    960
tatagtctat gcttagagat cttgtctggt tatggccatt gttttttact actttgatca   1020
cttaacttat agaccttttt tgacactgcc agtctcactt gtggcctatt tctctgcttc   1080
ttccaggaat ttgcttttat tagtcaagta taggggctgc caggttctgt gtctccatrg   1140
atatatgtgc ttcttttcct atagctaaat gtataataaa caggaacctg acctttacct   1200
cctttcagct gtttcaaaca ggtgcccagg atacctatgt cttagaatta gagtttcttc   1260
aaattgattc attgatttct caagtatgga ttatgtgaaa gagcccaggg acattatcca   1320
ttacagttta actctttcat ttaaaggtcc agagaggcaa gtgaattgtc taagttcata   1380
tattaggtca gtgactgaag ggaccaagaa cgcagacctg atttccaagc caagactccc   1440
atgctgcctc atttgtattc aagcctttaa caggagggca aagaggtgag aatgtgttaa   1500
aaaaaaaaaa aaaaaggg                                                 1518

<210> 285
<211> 707
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (499)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (631)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (649)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (653)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (671)
<223> n equals a,t,g, or c

<400> 285
gcaaatggag agcacctagg gctcgcggat gcggctttcc acgaggacag tcccgcgggt     60
atccatcata tacaggcatc tctcatcgat ttgcaccccc aaggtctcat tcctagggtg    120
gcacgccggg aagttcatct gtagaagcag gcgcgtggta aagtgtgcct gtggtcatgc    180
aaatactagt ttttgcttca cagggtcact cttaccacct aatggtggct ttgacactgt    240
aaccatttat cttgtttcat gttgtattta tgtargtgta tgtcatatct ccctaactaa    300
ggtgtttgat ataactagcc tcgttatcct cagctktwaa atggggacac tcaaggagtg    360
tacctacgat tataagagct gttgaatgtg aacagcctga cagggtaagc ctacaacaaa    420
tattattttc acctttgtca tcttataaat cccagtattc cacataaatg tcaggaacaa    480
ataatttttt tacaattgna taagaatcac agcaaaggan gctatcttgg gacctcttag    540
gaaagtggta ttggtaccaa agtaccccca ttgcaaaagt agggaataag aggaaagaag    600
aaaggttgca ttaccattcc catggnaaag nttttggggg ccaaaaccnc ttntttaaaa    660
agggttttgg naaactggcc attggggcca ttggggaacc ccttcct                  707

<210> 286
<211> 2029
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1669)
<223> n equals a,t,g, or c

<400> 286
gaataattgt ggacggtaca gtggcttttn aaaactacag tctttaggtg taaggtttgg     60
cgccgggagc aattttatga tcaaatatga tgaactccta agtcactgag gtgtgattgg    120
gccaatgttg gcatgaggtt cttgctctac ttccagtgtt ttgattccac tgggagaatt    180
tggcctagtg tgtggctttg gatgaatccg tgtagagaga ggtgagcttg tcctgttaca    240
gatgctgtca gacatagcga tagtaggcac ctagggagga agtggccgtt agttttacac    300
tgacttttta agaatggaga atgcacgtgg gtttctgttg cggatgattc atagtaagca    360
agcggttgat gctgttaata ccggccccac ccgattgaca ttaagtttat tcagctttta    420
aaaagatgaa gaactaaggg gaacaaattt aagtttgttg caacttagcc acacatgctt    480
ccctggtacc agctggaatc agcagctcac aggcatcttc aggacacttc agtgtatatg    540
acacagtact ttgttagcgt ctgcgtgtgt atggaaagtt gacaaaaaat ggcatgaaaa    600
gatcatgatt ggattttctt ttaaacctgc ccttctgtaa aaaatagttt atatattttt    660
aaattagtag gtatgtgtgg cttccttttt tcctaacatt cccagcaaat ttttgctgct    720
aagactatca ctgttaaagt gaaaattaca gggaaaaatg tgatgaatat accgtaactc    780
aaaatgtgat attttcttaa aatcactctt ttatgcttta ggaactggtt ggtctccact    840
ttgattatta gtgtaaagag cctgagtata cgtggatttc attgtaaaat ttaactcctt    900
gtcttttact tggggcacgg ggcccctgga gggcttccct actttcccca ctatgttaac    960
aggtaattct gatttatgcs tttagtttga cttattttta acaaaatatt agaagttatg   1020
ctttaaaatg tttaatgtgg actgaaattt tcatcttttg tttgagaatc tatgaagtgt   1080
atcatatacg tggcctaaag caaggtgtgt attttgttat tctgaaattg ttttgcatct   1140
ggacaaatac taaatatccc agtggccttt tttttttttt tttaaacctg tgtatccatc   1200
tcatcctttt gcgcattcct agtaagcaaa aaaatttgtt atgccatctt cattattcga   1260
attacagact gaaaaaatat ggccagtttt taaagaagtt tagattatgt tttccatgga   1320
aggacaagtc tgactgttca taggctgatt ttctttaaga ggattattct gttttacaat   1380
ttcaattcta gatcacattt tatatatgct gcatgccaaa aaaaaaaaaa gagaaaactg   1440
ccttttctgg tgtggagggg aagaaaaact aatattctac cttactagta gagttcaaaa   1500
caagttttca ctgagagcct tttcagtaaa agttaaacaa gtttgttttt tgagcatttg   1560
tcagttattc tatttcagaa gagtcaaaat tcaagcacga tacattttga aggctttgca   1620
aactcctaaa cccctgatga gtcctctcat tctggaagtg ggaatttgna gtagatactg   1680
atttgtcccg tagtatggca gatgacaggg aggtcttttc ccaagcaggc actcagaaca   1740
caggtcaccg tatgttctca gccagtaaca atcatactga ggacgaagga ctctccgttt   1800
gatgcagaca caattgtaat ggagatgtaa aacttcttag caatcagatg gataaattgt   1860
ttgcttttta ctttaaatag gaaattgttt tctaaaacta aaatacttga attgtcagac   1920
aatataatct cagcttgtat tagtttttga atgctcccat cgaggaagtg taacaatcca   1980
tgaaatgtga ataaatgaaa agtaaacaaa aaaaaaaaaa aaaaaaaaa               2029

<210> 287
<211> 2469
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1991)
<223> n equals a,t,g, or c

<400> 287
ctcgcckcgg cgcggagtcc cggctgcggg atagaccgag ggccatggcc gcctctcccg     60
gacccgccgg cgttggcggc gccggagcag tctacggctc cggctcttcg ggcttcgccc    120
tcgactcggg actggagatc aaaactcgct cggtggagca gacgctactc ccgctggttt    180
ctcagatcac cacgcttatt aatcataaag ataataccaa aaagtctgat aaaactctgc    240
aagcaattca gcgtgtagga caagctgtca acttggcagt tggaagattt gttaaagtag    300
gagaagctat agccaatgaa aactgggatt tgaaagaaga aataaatatt gcttgtattg    360
aagctaaaca agcaggagaa acaattgcag cacttacaga cataaccaac ttggaaccat    420
ctggaatctg atgggcagat cacaattttt acagacaaaa caggagtgat aaaggctgca    480
agattacttc tttcttcagt gacaaaagtg ttgttgctgg cagaccgagt agtcattaaa    540
cagataataa catcaagaaa taaggttctc gcaactatgg aaagactaga gaaagtgaat    600
agctttcaag agtttgtcca aatattcagt caatttggaa atgaaatggt ggagtttgca    660
catctgagtg gagatagaca aaatgatttg aaagatgaaa agaaaaaggc aaaaatggca    720
gcagctaggg cagttcttga aaagtgtaca atgatgcttc tcacagcttc aaagacatgt    780
ctgaggcatc ctaactgcga atcagcccat aaaaacaaag aaggagtatt tgaccgtatg    840
aaagtggcat tggataaggt cattgaaatt gtgactgact gtaaaccgaa tggagagact    900
gacatttcat ctatcagtat ttttactgga attaaggaat tcaagatgaa tattgaagct    960
cttcgggaga atctttattt tcagtccaaa gagaaccttt ctgtgacatt ggaagtcatc   1020
ttggagcgta tggaggactt tactgattct gcctacacca gccatgagca cagagaacgc   1080
atcttggaac tgtcaactca ggcgagaatg gaactgcagc agttaatttc tgtgtggatt   1140
caagctcaaa gcaagaaaac aaaaagcatc gctgaagaac tggaactcag tattttgaaa   1200
atcagtcaca gtcttaatga acttaagaaa gaacttcata gtacagcgac acagctggca   1260
gcagatctat taaaatacca tgctgatcat gtggttctaa aagcattaaa acttactgga   1320
gtagaaggaa atttagaagc tttggctgaa tatgcctgta aactctctga acagaaagag   1380
cagcttgttg agacctgtcg attgttacga cacatatctg ggacagaacc tctggaaata   1440
acctgtatac atgcagagga gacatttcag gtgactggcc aacagataat ttctgctgct   1500
gaaacattga cattgcatcc atctagtaaa attgctaaag aaaacctaga tgtattttgt   1560
gaagcttggg aatcccaaat tagtgacatg tcaacactgc tgagagaaat caatgacgtg   1620
tttgaaggaa gacgaggaga gaagtatggc tacctttcac ttccaaagcc aatgaagaat   1680
aatgcaaacc tgaaatcatt aaagccagac aagcctgact ctgaggagca agccaagata   1740
gcaaagcttg gacttaagct gggtttgctc acctctgacg ctgactgcga aattgagaag   1800
tgggaagatc aggagaatga gattgttcaa tatggacgga acatgtccag tatggcctat   1860
tctctgtatt tatttactag aggagagggg ccactgaaaa cttcccagga tttaattcat   1920
caactagagg tttttgctgc agagggttta aagcttactt ccagtgttca agctttttca   1980
aaacagctga nagacgatga caagcttatg cttctcctgg aaataaacaa gctaattcct   2040
ctatgccacc agctccagac agtaactaag acttctttgc agaataaagt atttctaaag   2100
gttgacaagt gtattacgaa gacaagatcc atgatggctc tcttagtcca acttctttca   2160
ctttgttata aactgctgaa gaagcttcag atggaaaata acggatgggt ctcagttaca   2220
aataaggaca ctatggatag taaaacttga gaagcttttg gggtcagatc tctggaacat   2280
catgtgatga agctgacatt tttaaaaatc aaatgatcct ttatcttttc agaaattcat   2340
caattttata aagaaaacaa tattgaaatt ttgctctatt ttctgatcat gaaactgatt   2400
gtaaagcttt ttgacaacta ataaatgtct tggtaattgc tagattctaa aaaaaaaaaa   2460
aaaaaaaat                                                           2469

<210> 288
<211> 573
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (543)
<223> n equals a,t,g, or c

<400> 288
tggtcgtcag tgagcgtttg gcgaaactcg cccgggaact gggctggcaa gacattaagg     60
tcgccgataa cgctgacaac gatgcgcttt tacgggcatt acaataactc tcataacagg    120
aagccataat gacggaacaa gaaaaaacct ccgccgtggt tgaagagacc agggaggccg    180
tggacaccac gtcacaacct gtcgcaacag aaaaaaagag taagaacaat accgcattga    240
ttctcagcgc ggtggctatc gctattgctc tggcggcggg catcggtttg tatggctggg    300
gtaaacaaca ggccgtcaat cagaccgcca ccagcgatgc cctggctaac caactgacgg    360
cattgcaaaa agcccaggag agccaaaaag ccgagctgga aggcattatt aagcaacaag    420
ctgcacaact taagcaggcg aatcgtcagc aagaaacgct ggcaaaacag ttggatgaag    480
tccaacaaaa ggtcgccacc attttccgga gcgatgctwa aacctgctgc tggctyargc    540
cgnttttctg gtgaaattcg gccggacgga agc                                 573

<210> 289
<211> 433
<212> DNA
<213> Homo sapiens

<400> 289
ggcacgagct cgaatgaggg aggagaggtg gagttgccgg ggctcaggcc cgcctcgagc     60
atgggcggat gagaggaktc gggagccgag gcctagggtc cttcgggtga ggggagacgg    120
agccagcgag gagatggagc agaagcttgt ggaggagatt cttcaagcaa tcactatgtc    180
aacagacaca ggtgtttccc ttccttcata tgaggaagat cagggrtcaa aactcattcg    240
aaaagctaaa gaggcaccat tcgtacccgt tggaatagcg ggttttgcag caattgttgc    300
atatggrtta tataaactga agagcagggg aaatactaaa atgtccattc atctgwtcca    360
catgcgtgtg gcagcccarg gytttgttgt aggrgcatgr ctttggtatg ggytattcca    420
gtattcggga ttt                                                       433

<210> 290
<211> 466
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (146)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (466)
<223> n equals a,t,g, or c

<400> 290
caatccatat gaaatgtggt ggtggattca gctgaaacca tggaatgaat gggggcgagg     60
ctggggatgt ggaaactgta tcccagggat cagatctaga cgactcagtn gatgattgca    120
tggggtgcag gtatccctca tgggcnttcc tgttcctttt gggcttatac atctcgtccc    180
tggcttcctg catgggagga ctttatggag ctccccgcat cctgcagtgc attgcccagg    240
wgaaagtgat ccctgcactt gcctgtctgg gacaagggaa ggggccaaac aaaacacccg    300
tggctgccat ctgcctgacc agcttggtga ccatggcctt tgtttttgtg ggtcaagtga    360
acgttctggc ccccatcgtc accatcaact tcatgctgac atacgttgca gtggactact    420
cttacttctc cctgtccatg tgttcctgca gcctgacccc ggtgcn                   466

<210> 291
<211> 1285
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1256)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1261)
<223> n equals a,t,g, or c

<400> 291
cgctgtncag ggttagtgct gggtctttgc aggaattggc tctgctgaca ggaattataa     60
gtaaagcagc acttcctgga atattaagtg aacttgacgt tgatgtaaat gaagggtctc    120
taatggagct acagggacat attggaagat tccagcgcca gtgcttagga ctactaagtc    180
gctttggtgg ctctgacaga ctgcgtcagt ttaaatttca agacgataat gtggagggag    240
ataaagtaag caagaaagat gagattgaac tggctatgca gcagatttgt gccaatgtaa    300
tggaatattg ccagtcactc atgttacaga gttcccctac cttccagcat gctgtgtgtc    360
tcttcactcc tagcctttca gaaacagtta atagagatgg accgcggcaa gatacccaag    420
ctccagtggt tccatactgg cgcctgcctg gtttaggcat tatcatctac ctgctgaaac    480
agagtgctaa tgatttcttc agctattatg acagtcatcg acagagtgtc agcaagctac    540
aaaatgtaga gcagcttccc ccagatgaga taaaagagtt gtgtcagtct gtgatgcctg    600
ctggtgttga taaaatctcc actgcycaga aatatgttct agcaagacgg cgcttggtga    660
aggtgatcaa caatcgagct aaactgcttt ccctttgttc ttttatcata gagacctgcc    720
tatttattct ttggcgccat ctggagtact acttgttaca ttgcatgccc acggattctc    780
aagattcctt atttgcctcg agaaccttgt ttaaaagcag aagactgcaa gattccttcg    840
cctcagaaac caatctagat tttagaagtg ggctggctat agtgagccaa catgatttag    900
accagcttca ggctgatgca atcaacgctt ttggagaatc actacaaaag aaacttctgg    960
acattgaagg attatattca aaagttcgat ctcgatatag tttcatacag gctcttgtca   1020
gacgtatccg tggcctcttg aggatatcaa ggaactgaga gcccgtgctt atgctcttct   1080
atgagagaga tgaattgggg agaattgtct ccattttata gattagtttc tttctaaatt   1140
atgaccaaaa atattttgct atttctttct ttgtatatgg acatcttttc tgtaaacttc   1200
ttcccctagt tccatcctca ctagtaaaaa ataaatactt tttaaaaaaa cagagnagtg   1260
ngagaaggga ggaaaaaaaa agggg                                         1285

<210> 292
<211> 1511
<212> DNA
<213> Homo sapiens

<400> 292
cattatccat actcatttat taatgtaggg gttacttagt gaaaccctga actaaaataa     60
gacagaggac aagaatacga agaaagacca atagaaaaca cggtaggatg ttaggcacgc    120
taaatggaaa atatgtgtta taatttttat ttcataagtg aacttgataa tagaaaatgc    180
atttttttat aaataaaaag taggtgtctg aataaaaata cctctacttg ggtagaggta    240
tttaaaattc tataattttg ttctgctatg gctaattctt acagaaccct ctttctggtt    300
ccactgtata ttattttaat gacacttctg cagtgggtat taagaataca gcttcacatt    360
tattcatcat tgtccattca ctcattagtt catgcaacca caaaaaggta ttataagaat    420
aatatttcat ttctgaggta aggaaattat catctagtat gttyttatat aacctactat    480
tcacaatgac atgtagaatt ctctctgtta twcaacatat gttcttgttc ttcaaaatct    540
gcaatatctg tagtctgatt cttggagact ggctcaccgc aattgtctag cagagcttta    600
gaccagggaa gtgccacaca gcaagtagtt tccatcacag tcttagctag tttattcctg    660
aatcctccca tatcttacag aaagagcaat gagtcttttg taaaccactc ccaggagggt    720
gatggtgagc actattattc cacacaccag gctgaatgcc catcgtggtc cccagtgagc    780
atacacttgg ctgatgaaca taggcccaag aatccgggct ccacttccag atgctgttaa    840
ccagcccatg tatacaccct gaggttttgg tcctagaatt tttgaatata gagtatagga    900
cataagattg cagactggat agcctaatcc tattagcaca gctgatgtaa ggaactgggc    960
cagatgaatc accggggtgt agaggcacca ggcttgttca atcgagcaac cagttggtct   1020
ttcattgtca tcttccattg gagacttcca aagaccaata ataatttccc caaatgtggt   1080
attagggatt gaattattgt gcaaatcttc ccactgtatt ttgggaaatt gatttcccca   1140
aggtaacaag rtaaagaagc caacccatac aacgatgagt cctcccagta gaatagcacg   1200
ctcgccaatc tttttggaaa gcaacttaac tcctaagaaa ataacaacgg cttcaacccc   1260
aagagcagca agtattatgc cattatataa cacagcttgt tcttgagtcc aggcatacat   1320
atccattgtt aatggagtaa tgatggtttc aaaaagggca aagataaata gagtcacaaa   1380
aaacagaaca ttgatggcca caacagcaac ctggtcaata tttccttggg gaacctgagc   1440
ttcatctgta cttgcttctt caaaattaat acttttacac tgtcttcctg agtccggacg   1500
cgtgggtcga c                                                        1511

<210> 293
<211> 541
<212> DNA
<213> Homo sapiens

<400> 293
aagataaagt aagtgctgtt tgggctaaca ggatctcctc ttgcagtctg cagcccagga     60
cgctgattcc agcagcgcct taccgcgcac ccgaagattc actatggtga aaatcgcctt    120
caatacccct accgccgtgc aaaaggagga ggcgcggcaa gacgtggagg ccctcctgag    180
ccgcacggtc agaactcaga tactgaccgg caagagcacc atttaccgtg gagagatgtg    240
cttttttgat tctgaggatc ctgcaaattc ccttcgtgga ggagagccta acttcctgcc    300
tgtgactgag gaggctgaca ttcgtgagga tgacaacatt gcaatcattg atgtgcctgt    360
ccccatttct ctgatagtga ccctgcagca attattcatg actttgaaaa gggaatgact    420
gctttacctg gacttgttgc tggggaactg ctatctgatg cccctcaata ctctawtgkt    480
akgctccaaa aaatctgggt agagctcttt ggcaaamtgg cgagtkggca gatatctgcc    540
c                                                                    541

<210> 294
<211> 464
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> n equals a,t,g, or c

<400> 294
ggcacgagct cacgtgcagg cgtcggtccg ggccactcca gtgacgaggg taggatccgc     60
agccccttcg cgaanccgag cgagaccggg cgacaggcag gcagagaata tgttattcca    120
tccttggccc acagatttat ggcagagatg gtggatttct ttattctctt ctttataaaa    180
gcaaccattg tcttaagcat tatgcacctc agtgggataa aggatatctc taagtttgct    240
atgcattata taatagaaga aatagatgaa gacacatcaa tggaagactt gcagaaaatg    300
atggttgtgg cacttatata cagattatta gtttgtttct atgagataat ttgcatttgg    360
ggagcaggtg gagctacccc agggaagttc ctgctggggc ttcgagttgt gacatgtgat    420
acatcagtgc ttattgcacc aagtcgggtt tttagtgatt cctt                     464

<210> 295
<211> 710
<212> DNA
<213> Homo sapiens

<400> 295
ggtttttttt ttggtttgtt tgatggacat cacggtgcct cagcggcaga gttgacatca     60
atggaactcc cagttttact tctccatcag ctttccaaat ttgatccttc ttaccaaatg    120
acaactgatg agcaacaaat aatcaattcc ttttacactg tgtttagaga agaatacaca    180
gcaatagaag acctcttttc tgccataaac aaaacagaag cagtgaggtg tgagtatgag    240
gacacacaca aagcctttgc aaaagcattt tggagaatgg ataggctttt aggtcttgga    300
agaaaagaag tgtccagggt tcaatggagt ggctgctctg cagttacttg katattggaa    360
ggcaaaccta aaagtcctta tgctcataag aattggaaaa gaaaaaatac ccatgatggg    420
ttggcagaga gctcccctty ccaggagatg ccaaaaataa tttctggaat attacatgtt    480
gcaaacactg atgtgattct gggtgtcatc tgtcacattt gtaaaatgag tatattatca    540
cacaatcctt cgcaactgtg ccagcacttc cctagcaaac tgcaaacttg agtttttcag    600
gaaaacagtt tacatgagaa aaggcaagtt ctttcccatt ttgaatgaag taccattaaa    660
ctctgtcacc tagtgaaaaa taataaaaat acttgcaact tttaaaaaaa               710

<210> 296
<211> 1154
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1154)
<223> n equals a,t,g, or c

<400> 296
ggcacgagca cagactgcca agtgggacaa ctttctggct tttgaaaggc tccttcttca     60
gagcattggg gagtcagcaa tgtccgttgt gttaaatcag ctgctgccca tgattaagcc    120
tgtaacccag agaaccaacg aggactacag ccctgaggaa ctgctgatcc ttctcatata    180
tatttattct gtcactggag agctcacggt agacaaagac ctgtgtgaag cagaagaaaa    240
agtcaagaaa gcattggctc aggtcttctg tgaggaatct ggatygtcac ctttgctgca    300
aaaaattacg gactgggact cttcaattaa tctgacattt cacaaatcca aaattgccgt    360
ggatgaactc tttacttcac ttcgggatat tgctggagct cggagtctcc tggaaacagt    420
ttaagtctgt atatgttcct ggaaatcata cccaccaggc atcttataag ccattgttga    480
agcaagttgt ggaggaaata tttcatcccg agaggccaga ttccgttgat attgaacaca    540
tgtcttcagg cctcactgat ctccttaaaa ctggatttag catgttcatg aaggtgagcc    600
ggcctcatcc tagtgactac cccctcctga tcctctttgt ggtaggtggg gtcacagtct    660
ctgaagtgaa aatggtcaaa gatcttgtgg catcattgaa gccaggaacc caggtaatcg    720
tgctgtccac acgactcctg aagccactta acattcctga gctgttattt gcaactgacc    780
gactgcatcc agaccttggc ttctgagcat ccgctaagaa gataagacct actcaagctg    840
gaaatgccga tgcaattttc tgccaccact ccaaatactc ctccacaacc agcgtccctg    900
tcactaattg cgagaatgat ggaattctgc ctgaagggtc ttgataccta ctcagtgagg    960
tactttgctt ggattgctgt gattcttaaa aaaaaaaaaa aaaagttttt ttattttcct   1020
gaaggcgaca gtctgtcttt tggcgagtcc aattagtgat cgtttccatt tatccttaac   1080
cctctgtttg tgatcttcct gattccacct acaagttcat tagttctaaa taaaagcctg   1140
ttggcaagtg aaan                                                     1154

<210> 297
<211> 531
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<400> 297
tgcaggaggc agaaagtaaa tctgaactta gtcagaacat ctctscccgg gaacattttg     60
tatttaccga tattgatggc caagtgtatc atctcactgt tgaaggaaac tcagtaaaag    120
acagtgctcg gattccacca gatggaagta tgggtagtat tacctgcatc gcttggaaag    180
gtgatacatt agtgcttgga gatatggatg gaaatttaaa tttctgggac ttgaaaggca    240
gagtatccag gtataagcca agaatgaatc ttgttatttc attaaaaaaa rgaaatgaaa    300
tctttttgtt ttgttttgtt ttgttttgtt ttgttgagat ggtgtcttgc tctgtcgccc    360
aagctggagt gcagtggtgc aatctcggct cactgcaagc tctgactccc gggttcatgc    420
cattctcctg cttcagctac ttgggaaact gaagcaggaa aatcgcttga acctgggaat    480
taaaagttgc aatgaactga aatcacacca ttgcgcttcn accctgggca c             531

<210> 298
<211> 2025
<212> DNA
<213> Homo sapiens

<400> 298
ctccaccacc gccgccacag tcttccagct ccacatcctg agaggacgcc tctggagccg     60
cgactgcccg gggttgtgcc ggccgccgct gccgcccagg ccgcctcagc tctcctctgc    120
gccggcccgc tcactccgcc cggccccagc cctagcgctg gccgcgaccc cggcggagat    180
catgaatcag acagataaaa atcaacaaga aatcccatca taccttaatg atgaaccacc    240
agaaggttca atgaaagatc acccacagca gcagccaggc atgttgtccc gtgtgactgg    300
gggtatcttc agtgttacaa agggagctgt tggtgccacc attggtgktg tggcttggat    360
tggtggaaag agtctggaag tgaccaaaac agctgttaca actgtgcctt ccatgggaat    420
agggctggtg aaagggggtg tctctgctgt ggctggaggt gttacagctg ttgggtctgc    480
tgttgtaaac aaagtgccct taacaggaaa gaagaaagac aaatctgact gaaatataga    540
gatacacttg cgctccacag cactgtaatg ccagtggcat tgaattgcta aattatggac    600
tacaaccaag tcaactgttt tggacgttta tcttctaaac tgctgtgttg aaagtattga    660
tgactggctt tcatctaaaa agaagagacc aatacgagca cagtatatga aggtttctca    720
tacttaagtt ccaggttttt atctggtaaa atgttacact tactcggttg taactgaaga    780
tatggtatgt ttgaatattt actataagtc tttcagtttg actaaaaatg tgaaagttga    840
atttagtaga tgatcttcac agttccatat gtataatgtg ccaggtaact cacctgcccc    900
ttaagaaggg aaccttgaat tacataagcc gtacctttga tgtgcctaat agtttcagat    960
gtcttagttt tttataacca tagttgatta ggccaagagg cattcatttc ttatttaagc   1020
tggcaaaatt agcaggaatt agagaagttt aaaaagataa atggttttat gataatgtta   1080
accatctttt gttagtaaat atgcgttcta ttattttaat cattgatgcc ttacaaaaga   1140
aaacatcttt tctaataccc tgaatatgtg ctgttcttag aatcatctat ggattctttt   1200
aaaggttgtt tgtgaaatta gttttccctt tttagaatct caggagtagt ggggtaaaga   1260
catttcctgc tgtcagtgga taagacagag cttgttaact gttttggcag tagttaaaat   1320
caaattgtac acttctcagc ctgggttcat gcttcatcat taatacacct cacagtgcct   1380
aaggaacatt tacttactgg tcagaaggta ttttggaaga gtttcatatt aaggaggaac   1440
aaataataat tttaagttct taaaaattac ctaaaacacc ccaaatataa aaagaagcct   1500
tcacacctat tctgtcttta ggatgtctta aattattagc agtactcctt ttttaaaaac   1560
actgtaaaag taaccacaaa tatgtgagga cttactattt taaatggaat ggaatgagct   1620
ccatagatta gttttgaata taaagtatat aaaagtgcat cagtggttta tataggcttt   1680
aaaaacatgt tatcttacag tcctttaaag cagccataga gtttgtatca tttttcaagc   1740
caatttcagt cagggatttg aattgtttga ttatggatga taaatgtgtc atatcttatt   1800
aatatgtctc atgtctcgtt ccttcttaat atgatttagc tggaattcat tttcttttcg   1860
tttcatgttt aatttcataa aacgtttaac aattggcata tatacttggc attcctgtcc   1920
accaaggatt gtaatccaag cctgggaaaa tcttaaattt ctttttactt aaatctggaa   1980
atttgtctcc attctgccac cttttttttt tttttttaaa agggg                   2025

<210> 299
<211> 1343
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1317)
<223> n equals a,t,g, or c

<400> 299
gcgnccgcct ygaacgggga gcaggcggcc tgctcmggag aaagagcgtc aacaccaccg     60
agtgcgtccc ggtgcccagc tccgagcacg tcgccgagat cgtcggcgcc agggttgtaa    120
aattaaagca ctgagagcca agacaaacac gtatatcaag actcctgttc gtggtgaaga    180
gcccattttt gttgtcactg gaaggaaaga agatgttgcc atggccaaaa gagagatcct    240
ctcagctgca gagcacttct ccatgattcg tgcatctcga aacaaaaatg ggcctgccct    300
gggaggatta tcatgtagtc ctaatctgcc cggtcaaacc accgtccaag tcagggtccc    360
ttatcgtgtg gtaggattag tggttggacc caaaggagca actattaaaa gaattcagca    420
gcagacccac acctacatag taactccgag cagagataag gracctgtct ttgaagtgac    480
agggatgcct gaaaatgttg accgagcacg ggaagaaata gaaatgcata ttgccatgcg    540
tacaggaaac tatatagagc tcaatgaaga gaatgatttc cattacaatg gtaccgatgt    600
aagctttgaa ggtggcactc ttggctctgc gtggctctcc tccaatcctg ttcctcctag    660
ccgcgcaaga atgatatcca attatcgaaa tgatagttcc agttctctag gaagtggctc    720
tacagattcc tactttggaa gcaataggct ggytgacttt agtccaacaa gcccatttag    780
cacaggaaac ttctggtttg gagrtacact accatctgta ggctcagaag acctagcagt    840
tgactctcct gcctttgact ctttaccaac atctgctcaa actatctgga ctccatttga    900
accagttaac ccactctctg gctttgggag tgatccttct kgtaacatga agactcagcg    960
cagaggaagt cagccatcta ctcctcgwct gtctcctaca tttcctgaga gcatagaaca   1020
tccacttgct cggagggtta ggagcgaccc acctagtaca ggcaaccatg ttggccttcc   1080
aatatatatc cytgcttttc taatggtacc aatagttact cctcttccaa tggtggttcc   1140
actctagctc acctccagaa tcaagacgaa agcacgactg gtgmatttgc tttragaaat   1200
gaggttattg ctgccctagt tccatgtggg ccacaacctc ttctgcatgg gaatgtgcca   1260
acaargatct gtgaaaagag aacgccatca tgtccagttt gccagacagc tgttgantca   1320
ggcaatccaa attcactctt gaa                                           1343

<210> 300
<211> 580
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (335)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (497)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (501)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (542)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (556)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (563)
<223> n equals a,t,g, or c

<400> 300
cagccacatn aaccggcagg atgtcggagg tgcggctgcc accgctacgc gccctggacg     60
actttgttct ggggtcggcg cgtctggcgg ctccggatcc atgcgacccg cagcgatggt    120
gccaccgcgt catcaacaac ctcctctact accaaaccaa ctaccttctc tgcttcggca    180
tcggcctcgc tctcgccggg tacgtgcggc cacttcatac gctcctgagc gcgctggtag    240
tggcggtggc cctcggcgtg ctggtgtggg cagctgagac ccgcgcactg tgcgccgctg    300
ccgccgcagc caccctgcag cctgcctggc cgcantgctt gccgtcggcc tcctggtgct    360
ctgggtcgcg ggcggmgctt gcamcttcct gttcagcatc gccgggccgg tgcttctgat    420
cctggtgcam gcctcgttrc gcctgcgcaa ccttaagaac aagattgaga acaagatcga    480
gaacattggt ctcaaangga ngccaatggg cctgctacta gaagcaatgg ggacaagagc    540
angaagctgg atctangccc ctnggatctg taacccagga                          580

<210> 301
<211> 609
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (497)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (499)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (540)
<223> n equals a,t,g, or c

<400> 301
gcacctcagm cgcctcctag cggcgcggcg ctcgctccta cgcctaaaat raccaatgtg     60
tgatttcagt ggaataaatg gcgtccaaag tcacagatgc tatagtctgg tatcaaaaga    120
agattggagc atatgatcaa caaatatggg aaaaatctgt tgaacagaga gaaatcaagg    180
ggctaaggaa taaaccaaag aaaacagcac atgtgaaacc agacctcata gatgttgatc    240
ttgtaagagg gtctgcattt gcaaaggcaa agcctgaaag tccttggact tctctgacca    300
gaaagggaat tgttcgagtt gtatttttcc cctttttctt ccggtggtgg ttacaagtaa    360
catcaaaggt catctttttc tggcttcttg tcctttatct tcttcaagtt gctgcaatag    420
tattattctg ctccacttct agcccacaca gcatacctct gacagaggtg attgggcccg    480
atatggctgg atgctgntnc tggggaactg gtgcattggc cagaattggt ttccacaagn    540
aacaccccaa aaccctcctc ttaagtacca ggggggggtt aaaaaaggaa agaaagggaa    600
aaattaaag                                                            609

<210> 302
<211> 1307
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (607)
<223> n equals a,t,g, or c

<400> 302
tccggaattc ccggagtcga cccacgcgtc nggtaaagac accaggagtt tctcgggccc     60
agctgtggct gctgccgggg agccccaagc cttggcgggt ccttgcggcg aataggagtc    120
tggtcaggcg tcaggctagt ccgacgaaga gtggagaatt tcaagattgt ggagttggac    180
tgaatgctgc acagttcaaa cagctgctta tttcggctgt gaaggacctg tttggggagg    240
ttgatgccgc cttacctttg gacatcctaa cctatgaaga gaagaccttg tcagccatct    300
tgagaatatg tagcagtggt cttgtcaaat tgtggagctc tttgaccctg ttaggatcct    360
ataaaggcaa aaaatgtgct ttccgggtga ttcaggtttc tccatttctt cttgcattat    420
ctggtaatag tagggaacta gtattggatt gaatgaatag tcttccattt tggaaacgtt    480
catccactct catatttatt ttttggtgcc tgcatgtttg aagactgaag caggctaaaa    540
gctcttgatg aaatttgagg gtgctgaaga tgttcccact aatttccagc catcaccttt    600
gggkggngtg ggcttcggag gacagtctgt ctgaacctgc cagtgctgac cctgcagcay    660
ttcagcatat gcacatcaaa gttggagacc gcgctgaact taggagggcc ttcacacaga    720
ctgatgtggc taccttctca gaattaacag gggatgtcaa tcctttgcat ttgaatgaag    780
actttgcaaa acacaccaag tttggaaata caattgtaca tggagttttg atcaacggac    840
ttatctcagc tctcctagga actaaaatgc cagggccagg ctgtgtattt ctttcccagg    900
aaattagctt tccagcccct ttatatattg gagaagttgt tttagcttct gcagaagtga    960
aaaagctgaa gcggttcatt gctattattg cagtgtcatg ttctgtaata gaaagtaaaa   1020
agactgttat ggaaggctgg gttaaagtta tggttccaga agcttccaaa tcctgaaata   1080
gatgttttaa agatgcaacc tcaaacacca atgctgttgt taaagagcct atggggaatt   1140
gctgctcttt accaaagaat ggttgatagg cccagaagcc catcttagtt aggggaaggg   1200
agcaggaaga gggttgttca aatgcccact ttccagtttg gccttatgct tcatgcagac   1260
ttgagtgtat gcaggatttc attatctgcc tgggtttttt gtttgtc                 1307

<210> 303
<211> 1246
<212> DNA
<213> Homo sapiens

<400> 303
ggcacgagca gcagctggaa gaggcatata gctctggaaa aggttgtaat gggagagttg     60
ttcctactga tgggggcaga tatgatgttc atttggggga gaggatgcgg tatgctgtat    120
actgggatga actggcatcg gaagtgagac gatgtacgtg gttttacaag ggggacaaag    180
acaataagta tgttccctac tcggagagct tcagccaagt tttagaggaa acttacatgc    240
ttgctgtaac tttggatgaa tggaaaaaga aactggaatc tcccaacaga gaaattatta    300
ttttacacaa tccaaagctt atggtgcatt accagccagt tgcagggtct gatgattggg    360
gttcaacacc cacggagcag ggtcgaccaa gaactgtgaa gagaggagtt gagaacatct    420
ctgttgacat tcattgtgga gaacctttac aaatagatca cttggttttt gtagtccatg    480
ggattggacc agcttgtgat ctccgctttc gaagcattgt acagtgtgtt aatgattttc    540
gcagtgtttc cttgaacttg ctacagacac attttaagaa agcccaagaa aatcagcaga    600
ttgggagggt agaatttctt ccagtcaact ggcacagtcc tttgcattct actggtgtgg    660
atgtagatct gcagcgaata accctgccca gcattaaccg cctcaggcac ttcaccaatg    720
acacaattct ggatgtcttc ttctacaata gtcccaccta ctgtcagact attgtggaca    780
cagttgcttc tgaaatgaac cgaatataca cactttttct acagaggaac cctgatttca    840
aagggggtgt atccattgct ggtcatagtt taggttcgct tatattgttt gatatcctaa    900
caaatcagaa agattctttg ggggatattg acagtgaaaa ggattcgcta aatattgtaa    960
tggatcaagg agatacacct acactagagg aagatttgaa gaaacttcag ctctctgaat   1020
tctttgatat ctttgagaag gagaaagtag ataaggaagc tctggcttta tgtacagacc   1080
gagatcttca ggaaatagga attcctttag gaccaagaaa gaagatatta aactatttcc   1140
arcacccaga aaaaactcca atgggtatta agagaccagc ccgcagcctg cttccagggg   1200
caaccatccc caaagaatcc tgagttctgg ccagtagcca gtaatg                  1246

<210> 304
<211> 1447
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (39)
<223> n equals a,t,g, or c

<400> 304
ggcacgaggc cgcggtggta cgctccaggc cgcgagccna ccgagcggac gccagtggat     60
gacccgcggc gggggaggag gagatcttgc tatcactgct attaccacgc cagaaccgcc    120
tgagaattga gattgaagaa gctctggaca tggacttgct caagcaggag gcagaacatg    180
gggccctgaa agtcctctat ctctctaagt acgttctcaa catgatggct ttgctgtgtg    240
caccagttcg agatgaagca gtgcagaaac tagaaaacat tacggatcct gtttggctac    300
tgagagggmt cttccaggtt ctgggccgga tgaaaatgga catggtgaac tacactatcc    360
agagccttca accccacctg caggaacatt ccattcagta tgaacgggct aaattccagg    420
aactcctcaa taagcagcct agtctcctta atcacaccac caaatggctg acccaagcag    480
caggagacct caccatgtca cctccgactt gcccagacac ttctgactcc tccagtgtgg    540
ctggcccctc tcccaatgag gcagccaaca acccagagcc cctcagcccc acaatggtgc    600
tgtgtcaggg cttcttgaac ctccttctct gggaccttga aaatgaagag ttccctgaga    660
ccctgctgat ggacagaacc cggctgcagg agctgaagtc ccagttgcac cagttaaccg    720
tcatggsctc agtcttgctg gtggccagta gtttctccgg cagtgttttg tttggctcac    780
cccaatttgt agataaactg aaacgcataa ccaaatcctt gttggaagac tttcactcca    840
ggcctgagga agctatactg actgtgagtg aacaggtatc tcaggaaatc catcaaagcc    900
tcaagaatat gggccttgtt gctctaagca gtgataatac agcatctcta atgggacagc    960
tccagaacat tgccaagaag gagaactgtg tctgcagtgt tattgatcag cggatccatt   1020
tgtttctcaa atgctgtttg gttcttggtg tgcagcggtc tctattagac cttcctggag   1080
gccttactct cattgaagca gaactggcag aactgggcca aaagtttgtc aacttgacac   1140
atcacaatca gcaggtgttt ggtccctact acactgagat cctaaaaacc ctcatttccc   1200
cagcccaggc actggaaaca aaagtggagt ctgtttgata gcgtcggctc agarccctgg   1260
taccttggac ccaagaggag cccatcatct tcctggagta acatcaccag tgaccagcag   1320
acagtgagct tctatyccag gccctgcagc cagtacacca aggctgtagg gatcaagcat   1380
gtaaacacca actggtccat acccattcat taataaactt cttaagtgca aaaaaaaaaa   1440
aaaacaa                                                             1447

<210> 305
<211> 1347
<212> DNA
<213> Homo sapiens

<400> 305
gggctctggc aatgtgccat ccacctcccc tctggtcagg ctggcggcac tgacaaggca     60
tccacagggg cagccatgct atggcccaga cctccggata tgcaggaacc ggggcctccc    120
acagaagtcc ctgcgcacag ccacaagatt aaggtacagg tcaggccggy tctgaagcca    180
gctgctgaca agctccgggt gccttgggtc cacttctaag aagatactac cagagtcttt    240
caggagccgg ggtgccaagg ccagaatgtg ggtaatgatg tccatgccyt cctccccacc    300
atccagggcc gcggggtctt catagctgcg gatctcaggg gccagctgct ccatgtcctg    360
gtggaagacg tagggagggt tgctgacaat caggtccatg gggccccagg gcaggtgtgt    420
ccagctcctt tctgaggtca tgtcgaggtg gatgatccaa atcctgtcct gcaaccgaag    480
cctctgagca ttctcatggg tcagagagat agcagcttcc cgcttatcca cagcaatgac    540
tcggctctgg gggagctggc tcagcaggct gagggagatg gctcctgatc cgcagcccac    600
ctccagaatg agggggctgc ctggggatcc cacagcatgg gacctctggg ccacctcttc    660
cagcacccac tcaaccagtt cctctgtttc tggccgcgga ataaacactg ggggcaccat    720
ccttaggctg agcccctgga agtcccactc tccaaggatg tactgcaccg gcatcctctg    780
caatcgacgg ctactcagct cccggataca ctgtagttgc tgagaggtca agggctgggt    840
ccaaagtgcc ggcctcaggc tctgaaatgt tttggctcca aggacatgag ccacgatgta    900
ctcactggat tcccgggcct cagggatacc cctcttctca aagaccccag tccagtggct    960
gaccagttct atggcactgg ataacccagc cagaggtggt tggggttgcc atgagctgaa   1020
ggcccagccc cgggtacttc ccctcctccc tgggccagac aggagggccc acagcattcg   1080
gccccaaagc tccatgtctc agggaaaggt tctccagagt gcttccaggt tcccaagtct   1140
gctttatgat gtcagctgct gaggtgagtg ctgagagtgg cccctggacc cagctgggtg   1200
gagatggaga ggtcacaagc tctggtgccc caaaatggct ctggtcctca gatatagttg   1260
gttgccaccc tgcctgaaag gctgccccac ccacccacca gccggagaag ctgccccgaa   1320
ctggacgccc ggacgtgcgt ggcccgt                                       1347

<210> 306
<211> 622
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (597)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (621)
<223> n equals a,t,g, or c

<400> 306
ggcacagcac atttattatc attatcaagt attgtgtact gtacagaatg atgtgtgctg     60
tgctatccag gaacacattt attatcatta tcaagtattg tgtactgtac aggatgatgt    120
gcgctgtgct atccaggaac acatttatta tcattatcaa gtattgtgta ctgtacagaa    180
tggtgtgcgc tgtgctatcc aggaacacat ttattatcat tatcamgtat tgtgtaytgt    240
acagaatggt gtgygctgtg ctatccagga acacatttat tatcattatc aagtattgtg    300
tactgtacag aatggtgtgc gctgtgcttt tatgcaagtg gcagcacagt agctttacac    360
gagcatcact agacacatga gtagcattgc actcggcaac aggaattttt tcaggcccat    420
tattataatc ttatgggacc gcatcctata tgcagtttgt cattgaccaa aatgtcctta    480
tgcgatgcat gactatattt gcaaaggact agtatctaga atacatttaa aagtcttaaa    540
atagtaacaa aacaaagaat gcaattagra cmtgagcaaa grtacaagca ctttcanggg    600
gaggtttcag ttgcaatagc nc                                             622

<210> 307
<211> 1824
<212> DNA
<213> Homo sapiens

<400> 307
tttccattac agtgcacatt tattgactct gtgtatcttc acagtgtgat cttcaccaca     60
gcttgcaaag tgtaaccact cagcaccttc tgcttccttc tgttcagttt ttccactgca    120
attcttccag cataattttc tgatagccag tgtatgactt tggctttgac ttgtttctac    180
acagtgggtc cagtcattta tttctggaac ttgatcagtc tttttccagg tatataagca    240
aatctttcca cactccaatc ctactgcaac cacgtatcgt tgagaagggt ggagcactgg    300
gcagacgctg acagctgtca cagccccacc cacgtccagg actgaggagc aggggccaat    360
gttgtgctca atacagtcat cagtggagtc acactcaccc cagacaacca cctttttgtc    420
tcgactccca gtgaagaaat acttgctgtc aggactccaa tcacaagacc aaataattct    480
actgtgcaca gaagtaattt tgttggtgaa ggcaaaaaga ctaaaaactg gctcgaactc    540
aggtgagatt gtatcctgct ttttccacaa tgaccaggtt cgatctctgg aaacagctag    600
taagaacttc tcattaggtg agaaggccat ctgcgtgact gtcaaactgt ggaaaactaa    660
attctgcacc tgtttccaag atgtagtgtt ccaaagaatg atagctgcat gctctttctt    720
agctgcctta caagctgagg caagcagagt ctttgaactg ttacaagtaa cacaaaatat    780
ttcataaccg tgcccatata gtttttgaac ttcaggccac aaagtattct gcagaagatg    840
atcctcagtg ggaggctcag taagtatgga gggctgaaag gccacctgct gatactcaaa    900
accagtacta gttaacagct cctcttcatc agaaggctga gaagctatat ctccctgaaa    960
gacagcttta tttgataatc ccaatgcagg gacagtggct ccttctggaa gatcactatc   1020
ttgattacag agcacatgat tcagtgattg tcctgtaatg gcacaaaaat tttccacaaa   1080
attccgaggt gcagaaaaaa cccgaagaac tttttcatct gctccagata caaactgaaa   1140
ccgattaatc attgccaaac atttcaggtc atacccatgt atctgaggcc ttgcaatttc   1200
atgccaagtc acctgtgatt ggtcttttct cttccatgga gcaaaaagtc tagttgtctg   1260
atcagtacca acagtgataa taaattctcc ttctggatcc cagactaggt cttggacacc   1320
atcaaagtgt cctgaaatga caatctctgg agtccactct cttgggttaa ctgtattctg   1380
tttccaaagg tgcaacgctc cgtggaaagc atgagcaatg atcatggagc catcttcatt   1440
gaactggcaa tcataaaatc ccaaagtatt cccacctact tcacctactc gaacctgttc   1500
tagccaaact cctgactctt catctggagc ccagagaatc atggttttat ccatggaagc   1560
agataataat ctcactggct gctgtaggac accatctttg taaaacacag gttgccagtg   1620
aactgcattt acccagtttt catgaccggc tagcactgtc tccagagtaa cagcaaatgc   1680
tattttaaca cttttcattt tctatggtaa aagtattttc cttcagtctt atgttatcgt   1740
catcctgagt ttctaaagat gttgacttta tatacagctt ccatattctt atcaggcaat   1800
cttgtgaaca gcttgctagg aact                                          1824

<210> 308
<211> 1882
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (282)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1846)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1882)
<223> n equals a,t,g, or c

<400> 308
gcttgcgctc cggagcgctt ggctctgctg gcgctgagaa atggaccaat tttgacaaga     60
tatagtgctg cagcgtgcct gatgggatat attcagtcat ggcgtccgaa ctttgtaaga    120
cgatctctgt ggcaaggcta gaaaagcaca agaatttgtt cttaaattat aggaatctgc    180
accattttcc attggagtta ctgaargatg agggactgca gtacttggag agactctata    240
tgaaaaggaa ctccctgaca tccttgccag aaaaccttgc tncagaagct tccaaacctt    300
gtggractgt ggmacttsaa ttgagatacc tgcactcaaa taacatagtt gtggttccgg    360
aagccattgg gtctcttgta aaactccaat gtctggatct tagtgacaat gccttagaaa    420
ttgtttgccc agaaattggt cgtctgagag ctttacgtca tcttcgatta gctaataacc    480
aactgcaatt cctacctcca gaggttggcg atttgaagga gctgcagaca ctagacattt    540
ctaccaatcg tttgctaact ttacccgaga ggcttcacat gtgcctttct ctgcagtacc    600
tcactgtgga ccgaaatcgt ctatggtatg tgccgcgcca tctctgccag ctgcccagcc    660
tcaatgagct ctccatggct ggaaaccgtc ttgcattttt gccacttgat ttaggtcgat    720
ctcgagaact acagtatgta tacgtggata acaacattca cctgaaaggc ttgccatctt    780
atctgtacaa taaagtcatc gggtgcagtg gctgtggtgc tcccattcaa gtttccgagg    840
tgaagctgct ttccttttca tcagggcagc gaaccgtttt cctcccagct gaggtgaagg    900
ccatagggac ggagcatgat cacgtcctcc ctctgcagga attggctatg agagggctgt    960
atcataccta ccacagcttg ctgaaagatt tgaactttct gtctccaatc tcattaccca   1020
gaagtctcct agagctgctg cactgccctc tggggcactg tcatcggtgt agtgagccta   1080
tgtttaccat cgtctacccc aagctctttc ccttgagaga gacgccaatg gcagggctgc   1140
accagtggaa gacaactgtt agttttgtgg cttactgctg ctccacccag tgtctgcaga   1200
cttttgacct gctgagttga taaacactca agaacctcag gagcgctgcc agcttgacac   1260
tggggaatcc agccagtcca gcacactctt ccatcctgtc ctgtccaatg cgggggcact   1320
gcagaactct ctagaaatgt catgattgag cttcagagct aaaatgcctt cacccttccc   1380
ccaagttgga atatatcctc ccccaaatta aggacccatt tgtcttctgt gtttttcctt   1440
tttatgtgag tgtgtctttt acagaaacca tttagattga tgggcctccc caaatctaat   1500
ttaaagcaag tttccggtcc ttggagaaca gtgacttgat catctagcca gattcccttt   1560
tgaacacaca taccttcagt gatgcttcct ctcctctycc ctcccttgct ttccccagag   1620
agttatttcc ctgagaccat gttytccaca ktgtctccag tggraacttg tcagtttttg   1680
aggrgtttca gcaaaccccg tggcctcaaa tggtcttgaa gtagcagggt ggggcgcctg   1740
agttggcaag caaagtgagg ctcccatgga ggctcagtga gggtcccaga gcacacaccc   1800
tctggaaagt tccagccttg tttatacgtt ctacagtgta gcaacngact ttttgtgaag   1860
gattttaaaa acaaaaatgt an                                            1882

<210> 309
<211> 980
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (582)
<223> n equals a,t,g, or c

<400> 309
caaaagctgg agctccaccg cggtggcggc cgctctagaa ctagtggatc ccccgggctg     60
caggaattcg gcacgagcag ggagacgggg gcctggagcc agccctgagc cagaggcaga    120
atggwtggac agacaggcca tggaggcagc actgagccag caccacacgt ccatcctggg    180
acaracgggc ctrgacttca cggcaagacc cccctctctt ccccactggg ttctgccacc    240
accaggagga tttcaagaaa gcaccaaaga ccagggagct cggatccata ctcggggggc    300
ctcagccctt gggaggggac acctgaggca gccagcgccc cctccccagt ccccagaact    360
gcctgcaggt gccttgttgc tggcttgtyt tcagaaaggg actgttctgg gtggctggat    420
ctccagggta ccctccaccc cagctgccaa gccctgggcc agcagcaccc ccttgtggcc    480
atcctgtgcc ttgktcccgg tggcctccct attggactac taggaggggc tggcagggcc    540
tccatagcac agaattgccc caaagccttg tyaagatgag tnaggatccc tcccccgctt    600
cctcccttct ttcccccttc ctccctcccc cttcataaag gcctcccttg tcaccttccc    660
tcccaccccg tctcagccct gtgctcctgg aggccctgct cccaaaaccg ctggaaggac    720
tggggcactt tctgccacag tagaacacag acagggcttc agatcaccca cgcctgtttt    780
cagctgtggg tggccatgca gacacgcgcc ctggcatgtg gggcctgggt gggcaggcag    840
gacctgggcc ctcccaccca tcagagccca ctcaggacca gcgttcggag ctcccacctg    900
gacgcatccc tcaccacgtc cggatttcct tctttggatg gaatgtaacg cgatctctat    960
ttaataaagg caggctttgc                                                980

<210> 310
<211> 513
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (492)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (494)
<223> n equals a,t,g, or c

<400> 310
gagatgttca agaacaccat ggccctcatg gacctggatg tgaagaagat gcccctggga     60
aagctgagca agcaacagat tgcacggggt ttcgaggcct tggaggcgct ggaggaggcc    120
ctgaaaggcc ccacggatgg tggccaaagc ctggaggagc tgtcctcaca cttttacacc    180
gtcatcccgc acaacttcgg ccacagccag cccccgccca tcaattcccc tgagcttctg    240
caggccaaga aggacatgct gctggtgctg gcggacatcg agctggccca ggccctgcag    300
gcagtctctg agcaggagaa gacggtggag gaggtgccac accccctgga ccgagactac    360
cagcttytca agtgccagct gcagctgcta gactctggag cacctgagta caaggtgata    420
caagacctac ttasaacaga ctggcagcaa ccacaggtgc cctacacttc aacacatctg    480
gaaagtaaac cnanaagggg aggaagacag att                                 513

<210> 311
<211> 532
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (484)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (523)
<223> n equals a,t,g, or c

<400> 311
ctcgcagntt gaaatccacc agagaagatg gctcttgatc cttacactga actccgaaaa     60
cagcctcttc gtaagtatgt caccccatca gactttgatc aactcaagca atttctcacc    120
tttgacaaac aggtccttcg attctatgca atctgggatg atacagacag catgtatggt    180
gaatgtcgga cctacatcat tcattactat cttatggatg atacggtgga aattcgagag    240
gtccacgaac ggaatgatgg gagagatcct ttcccactcc taatgaaccg ccagcgtgtg    300
cccaaagttt tggtggaaaa tgcaaaggaa cttccctcag tgtgtgctag aaatctctgg    360
accaaggaag tgttgggaat gggtatactg cttaaagrct tcattgttgg ggaagtcact    420
cactattcct tgggagaact ttcttccatt tatggattgt ggatcccttt ttactcggac    480
gggnatttac caaaggggaa ggtttgggat tcactggatt ttnccccggg tt            532

<210> 312
<211> 1051
<212> DNA
<213> Homo sapiens

<400> 312
ccgcctcgca catttagtct tgccgggagt ggtgtgattc ccgaccaaga tggcggccgt     60
ggggcgagtc ggctccttcg gttcttctcc gccgggatta tcctcgactt acactggcgg    120
ccccttgggc aacgagatag cgtcgggcaa cggtggcgcc gcggcaggcg acgacgagga    180
cgggcagaac ctttggtcct gcatcctcag cgaggtctcc acccgctcgc gctccaagct    240
ccctgcgggg aagaacgtgc tactgctggg tgaagatgga gctggaaaaa caagcttaat    300
aagaaaaatt cagggaatag aggagtataa gaaaggaaga ggattggaat atttgtactt    360
aaatgtgcat gatgaagaca gggatgatca aacaagatgt aatgtttgga tcttagatgg    420
agacctatat cacaaaggcc tccttaaatt ttcactggat gccgtatctc tgaaggatac    480
tctagttatg ctggttgttg acatgtcaaa gccttggact gctttggatt ctttacagaa    540
atgggcaagt gttgttagag aacatgttga caaactgaaa atccctcctg aagaaatgaa    600
acaaatggaa caaaagttga ttagagactt ccaagaatat gtagagccag gagaagactt    660
cccggcttct ccccagagaa gaaatactgc gtcacaagaa gacaaagatg acagtgtagt    720
tttacctctg ggtgcggata cacttacaca taacttgggc attccagtac tagtagtttg    780
cacaaagtgt gatgccatta gtgtattgga gaaagaacat gactacagag atgaacattt    840
kgattttatt cagtcacata tccggaagtt ttgtttacrg tatggtgcag cacttattta    900
cacttcagta aaagaaaaca aaaatataga cttagtatat aaatacatcg ttcagaaact    960
atatggtttt cccyataaga ttcctgctgt tgttgtggaa aaggatgcag tatttattcc   1020
agcagggtgg gataatggta agaaaatagg g                                  1051

<210> 313
<211> 916
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (825)
<223> n equals a,t,g, or c

<400> 313
ggcacgagct gcacgagact cagctgcggc gtctccacag gccgtcctca tcgtcagcgg     60
gaacctcagc ttcctgaact ggctnactat ggtgcccagc ctggcctgst ttgatgacgc    120
caccctggga ttcttgttsc cctctgggcc aggcagcctg aaggaccgag ttctgcagat    180
gcagagggac atccgagggg cccggcccga gcccagattc ggctccgtgg tgcggcgtgc    240
agccaacgtc tcgctgggcg tcctgctggc ctggctcagc gtgcccgtgg tcctcaactt    300
gctgagctcc aggcaggtca tgaacaccca cttcaactct cttcacatcg tcaacactta    360
cggggccttc ggaagcatca ccaaggagcg ggcggaggtg atcctgcagg gcacagccag    420
ctccaacgcc agcgcccccg atgccatgtg ggaggactac gagttcaagt gcaagccagg    480
tgaccccagc agacggccct gcctcatctc cccgtaccac taccgcctgg actggctgat    540
gtggttcgcg gccttccaga cctacgagca caacgactgg wtcatccacc tggctggcaa    600
gctcctggcc agcgacgccg aggccttgtc cctgctggca cacaacccct tcgcgggcag    660
gcccccgccc aggtgggtcc gaggaggagc actacaggta caagttcagc cgtcctgggg    720
gcaggcacgc cgccgagggc aagtggtggg tgcggaagag ggatcggagc cttatttccc    780
tccgttcagc ctgggaggag ctgagggccc ttatttcaag gaccntgggt gggccttttg    840
cccggggccc ttttagacgt ggcaacagaa ttaaaggcga ggacccagcc ccttgggggt    900
ttcagcaaaa aaaaaa                                                    916

<210> 314
<211> 446
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (380)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (439)
<223> n equals a,t,g, or c

<400> 314
ccagttggtt gccgcggagt ctctccgagc agcgcatttg tcttctaggc tgcttggttc     60
gtgcctccga gaaaggggtc tcctgctgcc agctaagtgt gggagaactt gtgcacgtat    120
ctcccctccg aatcccaacg atgggtaacg ccagctttgg ctccaaggaa cagaagctgc    180
tgaagcggtt gcggcttctg cccgccctgc ttatcctccg cgccttcaag ccccacagga    240
agatcagaga ttaccgcgtc gtggtagtcg gcaccgctgg tgtggggaaa agtacgctgc    300
tgcacaagtg ggcgagcggc aacttccgtc atgagtacct gccgaccatt gaaaatacct    360
actgccagtt gctggggctn gcagccacgg tgttgctttt ccctggcaca ttcaccgaac    420
aggcaagagt gggccgacng gcaaac                                         446

<210> 315
<211> 1733
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1459)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1509)
<223> n equals a,t,g, or c

<400> 315
aaacattacc gttactctgc ccagcccagt catggaagac tgtagtagat tctcagcaag     60
tacatgtttg atacgttcca cgtttcccat ttaatttcaa tacatttaaa atattttgaa    120
aattaggtga cagwatgttg actgctggtc ctgtggccag agattgtgga atgattctac    180
ctcaggataa agtgattatt gctgaagcat tacctccaaa ggatgggaaa gttgccaaaa    240
taaattggca ttatgcagac tccctcacgc agtgcagtca tccatcagca attgacccag    300
aggctattcc ggttaaattg gtccatgata gcttagagga tcttcaaatg actcgttatc    360
attttgcaat gaatgggaaa atcattctca gtgatactgg agcattttca agaccttgtt    420
cctaagttga tgttgcatgg caccgtgttt gcccgtatgg cacctgatca gaagacacag    480
ttgatagaag cattgcaaaa tgttgattat tttgttggga tgtgtggtga tggcgcaaat    540
gattgtggtg ctttgaagag ggcacacggg aggcatttcc ttatcggagc tcgaagcttc    600
agtggcatct ccctttacct ctaagactcc tagtatttcc tgtgtgccaa accttatcag    660
ggaaggccgt gctgctttaa taacttcctt ctgtgtgttt aaattcatgg cattgtacag    720
cattatccag tacttcagtg ttactctgct gtattctatc ttaagtaacc taggagactt    780
ccagtttctc ttcattgatc tggcaatcat tttggtagtg gtatttacaa tgagtttaaa    840
tcctgcctgg aaagaacttg tggcacaaag accaccttcg ggtcttatat ctggggccct    900
tctcttctcc gttttgtctc agattatcat ctgcattgga tttcaatctt tgggtttttt    960
ttgggtcaaa cagcaacctt ggtatgaagt gtggcatcca aaatcagatg cttgtaatac   1020
aacaggaagc gggttttgga attcttcaca cgtagacaat gaaaccgaac ttgatgaaca   1080
taatatacaa aattatgaaa ataccacagt gttttttatt tccagttttc agtacctcat   1140
agtggcaatt gccttttcaa aaggaaaacc cttcaggcaa ccttgctaca aaaattattt   1200
ttttgttttt tctgtgattt ttttatatat ttttatatta ttcatcatgt tgtatccagt   1260
tgcctctgtt gaccaggttc ttcagatagt gtgtgtacca tatcagtggc gtgtaactat   1320
gctcatcatt gttcttgtca atgcctttgt gtctatcaca gtggagaact tcttccttga   1380
catggtcctt tggaaagttg tgttcaaccg agacaaacaa ggagagtatc ggttcagcac   1440
cacacagcca ccgcaggant cagtggatcg gtggggaaaa tgctgcttac cctgggccct   1500
gggctgtana aagaaracac caaaggcaaa gtacatgtat ctggcgcagg arctcttggt   1560
tgatccaraa tggccaccaa aacctcagac aaccacagaa gctaaagctt tagttaakga   1620
raatggatca tgtcaaatcw caccataaca tagcartgaa tcagtctcag tggtattgct   1680
gawarcagta ttcaggaata tgtgatttta ggaatttctg atcctgtgtg tca          1733

<210> 316
<211> 505
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (470)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (495)
<223> n equals a,t,g, or c

<400> 316
gacctgcatc ttgtatctga ataaccaggt gtttgtgtct ctggccaatg gagagcttgt     60
ggtctaccaa agggaagcag gccatttctg ggacccccag aacttcaaat cagtgacctt    120
gggcacccag gggagcccca tcaccaagat ggtatctgtg ggtgggcggc tgtggtgtgg    180
ctgccagaac cgagtccttg tcctgagccc tgacacgctg cagctggagc acatgtttta    240
cgtgggtcag gattcaagcc gctgcgtggc ttgcatggtg gactccagcc tgggtgtgtg    300
ggtgacattg aaaggtagtg cccacgtgtg tctctaccat ccagacacct ttgagcagct    360
ggcagaagta gacgtcactc ctcccgtgca caggatgctg gcaagctcgg atgccatcat    420
ccggcagcac aaagctgcct gtctgcgaat cacagcgctg ctggtgtgtn aagaactgct    480
gtgggtgggc accantgctg gtgtc                                          505

<210> 317
<211> 484
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (277)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (474)
<223> n equals a,t,g, or c

<400> 317
cctcgaaaat actgaagttc ctgttggctg tcttatggtc tacaacaatg aagttgtagg     60
gaaggggaga aatgaagtta accaaaccaa aaatgtatgt gagttgagca gtataattgc    120
aaacatacag tagtgatggg tggactggag agaatttacc acagttggtg tgaaggctac    180
tcgacatgca gaaatggtgg ccatcgatca ggtcctcgga ttggtgtcgt caaagtggca    240
agagtccctc tgaagtattt gaacacactg tgttgtnatg tcactgtgga gccctgcatt    300
atgtgtgcaa ctgctctccg cctgatgaaa atcccgctgg ttgtatatgg ctgtcagaat    360
gaacgatttg gtggttgtgg ctctgttcta aatattgcct ctgctgacct accaaacact    420
gggagaccat ttcagtgtat ccctggatat cgggctgagg aagcagtgga aatnttaaag    480
acct                                                                 484

<210> 318
<211> 1264
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1262)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1264)
<223> n equals a,t,g, or c

<400> 318
caaacccaag gagagagcac gagcctgagt ttagctttga gtttgggcca atccacagat     60
agcttaggta cctatccagc tgatccacaa gcaggaggag ataatccaga agttcatggt    120
caagtagaag tgaaaactga gaagagrcca aacttcgttg atcgacaggc atccacagtt    180
gagtatctcc caggcatgct acattcaaat tgccctaaag gtctcctacc caaattctcc    240
agctggtctt tggttaaact aggccctgct aagtcttata actttcatac aggtttggac    300
caacagggct ttattccagg aacaaattat cttatgcctt gggacattgt catcaggact    360
agagctgaag atgaaggaga cttagacaca aactcttggc ctgctccaaa taaagctatt    420
cctggaaaga gaagtgcggt tgtaatggga agaggaagac ggcgagatga catagctcga    480
gcttttgtgg gctttgaata tgaagactct cgaggtcgga gattcatgtg ctctgggcct    540
gacaaagtaa tgaaagtaat gggaagtggg ccaaaggaat cagctttaaa agccctaaat    600
agtgacatgc ccttatatat tctgtcatcc tctcaaggta gagggctgaa acctcattat    660
gctcaactta tgaggctttt tgttgtggtt cctgatgctc ctttgcagat aatactaatg    720
cctcaggttc agccaggccc accaccatgt ccggtattct acccagaaaa acaagaaatc    780
acccttccac ctgatggcct ttgggttttg agatttcctt atgcatatgt gactgagaga    840
ggaccttgtt tcccccctaa ggaaaatgtg cagttaatga gctacaaggt gctccgtggg    900
gttcttaagg cagtaacaca ataagtgttt tccagccagt tcaatcctat acttgagctg    960
gtttttgttt ttggtatttg tggctgtgtt tttggtatgt gtttactgtg ttttcccaaa   1020
tccaaaatgt gttttggtta caggagttca gtatttggaa actaatttgt tctacttttt   1080
cattatattg ttgatattta ttgtaaacgt gactacaact ttctaataaa gattggttgt   1140
tctagaaaag aatataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1200
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagggggggc   1260
cncn                                                                1264

<210> 319
<211> 677
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (571)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (592)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (600)
<223> n equals a,t,g, or c

<400> 319
gaatatctct aaataccgtc acattctgag tactgggtat tgggtttcag catataaatt     60
ttcggaggct gataacagaa ttcaacccat aacaccsgct ctagtagtgt tttaccttcc    120
tttttccata tgccttagtt agtttaggcc tgtggtgctg tgagcctgtg atgtgggaaa    180
acttgattac tcctccatgt agtaacctca atgggaatgg ctcaggcaag cagatgccac    240
catgccacag ggtcactgag gggcccaggg tcatgctaag tcattccatc aacaacatct    300
tccgtgtggt caccactggg tccctgctgg caagaagagg aaagagactg tggaggagcc    360
gtgctcaatg tccaaagccc caggctggca ttggacatcc cattgtcccc aggctggcat    420
caccgctgct cacatcctat tgggagaact cagtcgcacc taagtgcaag ggacgctggg    480
aagtgcagtc cacctggggg cccaggaaga agggcagagt gaatgggcca catacagcag    540
tctttgccac atcctgcctt ttcctctctt ncccagtcca cttaggaatc tncccactgn    600
ttcttggatt tttaaacttt ctggctggta ttttcagcag ctgggtgact tttcatcttc    660
cttgcttcat gccttca                                                   677

<210> 320
<211> 1917
<212> DNA
<213> Homo sapiens

<400> 320
tcgacccacg cgtccggaac aatatggcgg atggcgagga gccggagaag aaaagaagga     60
gaatagagga gctgctggct gagaaaatgg ctgttgatgg tgggtgtggg gacactggag    120
actgggaagg tcgctggaac catgtaaaga agttcctcga gcgatctgga cccttcacac    180
accctgattt cgaaccgagc actgaatctc tccagttctt gttagataca tgtaaagttc    240
tagtcattgg agctggcggc ttaggatgtg agctcctgaa aaatctggcc ttgtctggtt    300
ttagacagat tcatgttata gatatggaca ctatagatgt ttccaatcta aataggcagt    360
ttttatttag gcctaaagat attggaagac ctaaggctga agttgctgca gaatttctaa    420
atgacagagt tcctaattgc aatgtagttc cacatttcaa caagattcaa gattttaacg    480
acactttcta tcgacaattt catattattg tatgtggact ggactctatc atcgccagaa    540
gatggataaa tggcatgctg atatctcttc taaattatga agatggtgtc ttagatccaa    600
gctccattgt ccctttgata gatgggggga cagaaggttt taaaggaaat gcccgggtga    660
ttctgcctgg aatgactgct tgtatcgaat gcacgctgga actttatcca ccacaggtta    720
attttcccat gtgcaccatt gcatctatgc ccaggctacc agaacactgt attgagtatg    780
taaggatgtt gcagtggcct aaggagcagc cttttggaga aggggttcca ttagatggag    840
atgatcctga acatatacaa tggattttcc aaaaatccct agagagagca tcacaatata    900
atattagggg tgttacgtat aggctcactc aaggggtagt aaaaagaatc attcctgcag    960
tagcttccac aaatgcagtc attgcagctg tgtgtgccac tgaggttttt aaaatagcca   1020
caagtgcata cattcccttg aataattact tggtgtttaa tgatgtagat gggctgtata   1080
catacacatt tgaagcagaa agaaaggaaa actgcccagc ttgtagccag cttcctcaaa   1140
atattcagtt ttctccatca gctaaactac aggaggtttt ggattatcta accaatagtg   1200
cttctctgca aatgaaatct ccagccatca cagccaccct agagggaaaa aatagaacac   1260
tttacttaca gtcggtaacc tctattgaag aacgaacaag gccaaatctc tccaaaacat   1320
tgaaagaatt ggggcttgtt gatggacaag aactggcggt tgctgatgtc accaccccac   1380
agactgtact attcaaactt cattttactt cttaaggaaa atctccacat aatagaaaac   1440
tcatggaaat aatatacttt gtggatgcta agaagttgaa tcgatgtcat ttttagcaat   1500
agtgttgcca cgatttgtct ttttttatat aatgaaccac tcttttttaa ctttgtaacc   1560
ttcccttgaa gacagaattt tggtgttggt gcttgtaagc attttcatta ataatatgag   1620
aaatgatacc tggagagaga gattatgagc aaatgtattg cttcttttag aggaggaagc   1680
atacaacctc ttttgtgtga attttgttat tatggtcaaa gaatgcattc ctaagttttc   1740
atttgagtac ccaaatacac aaaaggtgtc cctttaagga aaataaagaa ttaagtttta   1800
aataacatta cattttacaa tctgacatct ggagtatatt gaacataggc tatttcttga   1860
tataacactc atttaattgt ggccatccaa atgaatatta ttgcagaatt tatcttg      1917

<210> 321
<211> 575
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (537)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (542)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (553)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (567)
<223> n equals a,t,g, or c

<400> 321
ggcasgrgct accccagcag caccaatgtg gagaccgtca acgatggtgc tgagtcggcc     60
atgttcaagc agctgttcca gaagtggtca gtaaaggacc agaccatggg cctggggaaa    120
acgttcagca ttggtaaaat tgctaaagtt ttccaggata aatttgatgt gactctgcta    180
cacaccaagc cagaggtagc tgcccaggaa agaatggtcg atgatggcaa cggaaaagtt    240
gaggtctgga gaattgagaa cctggagctg gtccctgtgg agtatcaatg gtatggcttc    300
ttttatgggg gagactgtta tctggtcctc tacacatacg aggtaaatgg gaagccacat    360
cacatcttgt acatctggca ggtaggcctg gcacagctty agctttggat cctgatgtgt    420
cctctggcca ctgggctggg gcggggagca tgggtccttc atggcctctc accattgcag    480
ggccgccacg cctcacagga tgagctggca gcctcagcat accaggcagt ggaagtngat    540
cngcagtttg atngggctgc tgttcangtt cgagt                               575

<210> 322
<211> 825
<212> DNA
<213> Homo sapiens

<400> 322
aattccgagg aatacattca taaaccatgt gatactgttt cttcatgytm atattagttt     60
ccaaaaaaat gcagtctaat cctttatctt caaacatctt taccaatgat tttctgaaca    120
tctggatctc ctycccagat gtcttcatcc caacaaagta gctgctctat ggtgctgcaa    180
agggactatc aggcagtgcc cctcagtaag agaccgtacg ttgggtaaac ataaataaac    240
cttaacacct attgcaacaa taagatgctt gggaaattga gagctgtcaa aacaatacag    300
acatttttcc atttgtgcag caagactccg atgctcagca atagcttttt tcctttggtt    360
ctcttcctct tcaccaagac gttctctctc agctgctttg gagacaaaca tgtcatccag    420
ggtgtaatag tctccatctg tttttcccat aaacttagat gccattctca taaagagctt    480
gttttgattt tctgctgttc ccatcttttc atttttgact aaatcattta ggcttagatt    540
atcatcatca tgaaagtatc tgaccctttc tctttcctca tgggttgaaa ccatctgtct    600
ctttcttctt cctccttgtg attccagaga ttttccgggt gtgttcacag gccatactct    660
tccagactga tctgttctga caaggawtac ttcttgctgg tcttcattct ctaccccaga    720
tttttttggt atctgtgtta tagtttcttt gaatttattt gccttttcaa gttgaacttt    780
aagttgttca gctaattcca tattccccat catctytgyt ttgac                    825

<210> 323
<211> 861
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (802)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (846)
<223> n equals a,t,g, or c

<400> 323
agagagggga cactgacctc accttcttct ccgaggactg ttttcacttc tcagaccgcg     60
ggcatgccga gatggccatc gcactctgga acaacatgct ggaaccagtg ggccgcaaga    120
ctacctccaa caacttcacc cacagccgag ccaaactcaa gtgcccctct cctgagagcc    180
cttacctcta caccctgcgg aacagccgac tgctcccaga ccaggctgaa gaagcccccg    240
aggtgctcta ctgggctgtc ccagtggcag cgggagtcgg ccttgtggtg ggcatcatcg    300
ggacagtggt ctggaggtgc aggagaggtg gccggaggga agatcctcca atgagcctgc    360
gcactggtgc cctctaggcc cgggggtggg tcctcaccct aaactcccta tagccaccct    420
cttcactgcc ctctgcccca gccactcccg gccaccagga catgcttcaa tgcctggtgc    480
cataggaagc ccaggggaca gtcacaactt cttggggcct gggcttcttc caggcctatg    540
ctcctggaat ggatacattt aaataaagtc caaagctatt ttattcctgg gtttgcctgc    600
gtgaagcact caccttccat ctcttgtgca gcccaggtgt gggagctgcc actttttgtg    660
gcctgcctcc agcagggctg cccaagccac gaccaaccag agcccaaact gcctgccacc    720
acgagcatat cctcaagtca ccaaacccac tatttcaaag gcagaaaaaa tgctggtcac    780
caggtggtgg cttggaattt tngagcttgg ttggttgcca tttagtccaa ttcaacaaaa    840
tacctnttag ggaatttttt t                                              861

<210> 324
<211> 1396
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1356)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1360)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1393)
<223> n equals a,t,g, or c

<400> 324
ggcgggcgcg gggacccgat gcgcgggagc ggaggccgag atggcttcgg cgggaggcga     60
agactgcgag agccccgcgc cggaggccga ccgtccgcac cagcggccct tcctgatagg    120
ggtgagcggc ggcactgyca gcgggaagtc gaccgtgtgt gagaagatca tggagttgct    180
gggacagaac gaggtggaac agcggcagcg gaaggtggtc atcctgagcc aggacaggtt    240
ctacaaggtc ctgacggcag agcagaaggc caaggccttg aaaggacagt acaattttga    300
ccatccagat gcctttgata atgatttgat gcacaggact ctgaagaaca tcgtggaggg    360
caaaacggtg gaggtgccga cctatgattt tgtgacacac tcaaggttac cagagaccac    420
ggtggtctac cctgcggacg tggttctgtt tgagggcatc ttggtgttct acagccagga    480
gatccgggac atgttccacc tgcgcctctt cgtggacacc gactccgacg tcaggctgtc    540
tcgaagaktt ctccgggacg tgcgccgagg gagggacctg gagcagattc tgacgcatac    600
accaccttcg tgaagccggc cttcgaggag ttctgcctgc cgacaaagaa gtatgccgat    660
gtgatcatcc cacgaggagt ggacaatatg gttgccatca acctgatcgt gcagcacatc    720
caggacattc tgaatggtga catctgcaaa tggcaccgag gagggtccaa tgggcggagt    780
acaagcggac cttttctrag ccaggggacc accctgggat gctgacctct ggcaaacggt    840
cacatttgga gtccagcagc agaccccact gaggggctgc cgagcctcag ggcaggtctc    900
ccgcccggsa tgtgtgttca gggamtkagg cctggggacg cccacccaca cccactgctt    960
cctctcggcg caccccaggg gagtgttagc agcgaggcct tcctcactca ggagtggaaa   1020
ctcagatgtg tcactcagac tcaacttgct gggacactga caggcgttcc tgaggttttc   1080
agccacttag gctcgttgcg gtttaaagat ccctctaggt cactgagaaa tgccacagaa   1140
tgtgcaggaa gcctgggagg cttctgtgag gaatgtgagg cacattattg gggaaattga   1200
ggagacagcc tagacactgg ctggcctgat gttttgttga cagtgaaccc acagtgggag   1260
agagtttttt ccagtctgat ctggttctta cacacacaca taactcaaaa gttttgtgaa   1320
caagtacttt ccttttttaa caggttaaca agtccnccan gttttccggt tttccggttt   1380
ccataaacac aanggc                                                   1396

<210> 325
<211> 1140
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (575)
<223> n equals a,t,g, or c

<400> 325
tacggctgcg agaagacgac agaagggggg gcagacccaa gtgccggcgg cggagactgc     60
agtggagcca gtaccggctg tagtggccgg ggccgtggcg ggagagtcat gtcagagccg    120
cagccgcggg gcgcagagcg sgatctctac cgggacacgt gggtgcgata cctgggctat    180
gccaatgagg tgggcgaggc tttccgctct cttgtgccag cggcggtggt gtggctgagc    240
tatggcgtgg ccagctccta cgtgctggcg gatgccattg acaaaggcaa gaaggctgga    300
gaggtgccca gccctgaagc aggccgcagc gccagggtga cygtggctgt ggtggacacc    360
tttgtatggc aggctctagc ctctgtggcc attccgggct tcaccatcaa ccgcgtgtgt    420
gctgcctctc tctatgtcct gggcactgcc acccgctggc ccctggctgt ccgcaagtgg    480
accaccaccg cgcttgggct gttgaccatc cccatcatta tccaccccat tgacaggtcg    540
gtggatttcc tcctggactc cagcctgcgc aastnctacc caacagtggg gaagcccagc    600
tcctcctgat catactctgg tacctggcct gtgcatcggc ctcctgcttc atgtcaacct    660
cctactcctg ccagggaatg tggacacctg gctccctggt gtccaaagac cctggcacct    720
gggtgggttt gagctggaca gaagcttaga gacaaaggct tcaagaagca gtggctgcag    780
ggagtcacag aagggcagga cctgaacgct gtctgcttcc ctggaatcca agatgctgag    840
tggaagtgga ccctgggtgg cccggccctg tctttttcag gaaaattaca tcctcccatg    900
gaggatgaga gactgaggct cagggagggc aaggaatagg cccaagatca cttggcaagc    960
tgggcaccca ggacccccag gtgcttgaca gagtcacccc atggtggtat ggctgaacaa   1020
ggagcggcag acaactcagg gagaaactca ggagtgcagt accagggaca cctcaggaca   1080
gattctctgg ccaggccctt ccctgaccca ataaatcctg aagaggtaaa aaaaaaaaaa   1140

<210> 326
<211> 546
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (314)
<223> n equals a,t,g, or c

<400> 326
gaaaacccgt aggggcaagg ctcgccgtan agctgccaag ctccagtcat cccaagaacc     60
tgaagcacca ccacctcggg atgtggccct tttgcaaggg agggcaaatg atttggtgaa    120
gtaccttttg gctaaagacc agacgaagat tcccatcaag cgctcggaca tgctgaagga    180
catcatcaaa gaatacactg atgtgtaccc cgaaatcatt gaacgagcag gctattcctt    240
ggagaaggta tttgggattc aattgaagga aattgataag aatgaccact tgtacattct    300
tctcagcacc ttanagccca ctgatgcagg catactggga acgactaagg actcacccaa    360
gctgggtctg ctcatggtgc ttcttaacat catcttcatg aatggaaatc ggtccagtga    420
rgctgtcatc tgggaagtgc tgcgcaaktt ggggcttgcg ccctgggtta tgattggggc    480
tctctcarcg cttggtgtcc gtgttgtccy tttgggcaar aaaagaasgt cctaggattg    540
catcag                                                               546

<210> 327
<211> 1150
<212> DNA
<213> Homo sapiens

<400> 327
ggcacgagct tggggcgtgg cataccaagt gcaaggggag caggtaagca aggccctgaa     60
gtacctgaat gtgcgagagg cagtgcttgg tggctacgat accaaggagg tcaccttcta    120
tccccaagat gctcctgacc aaccactgaa ggcattggcc tatgtggcca ccccacagaa    180
ccctggttac ctgggccctg cgcctgaaga ggccattgcc acgcagatcc tggcctgccg    240
gggcttctcc ggccacaacc ttgaatactt gctgcgtctg gcagacttca tgcagctctg    300
tgggcctcag gcgcaggacg agcacctggc agccatcgtg gacgctgtgg gcaccatgtt    360
gccctgcttc tgccccaccg agcargctct ggcgctggtg tgaggggctg agcccctgcg    420
gggagtgctc atgtggacat cagggccaga cacccactcc agtgcacaag acagattgcg    480
accgcttgag cccactgagc aratatggtg ggtggctgga ggcttctctt tctcagtccc    540
tgcctgtctg ccagcctgca gctctcctgc ttgacactga cttactactt gaaactttat    600
ttattgcacc atgttggtgt ggtgggcagg tggagggcct gccctggaca caggggccct    660
gctgagcagt ggcmccatcc tggaacttga ccagattccc cccagtgctg ctgctaaccc    720
cacaccaccc aggcctccac ctccccaggg agtctccaag agcctcgatc ctctgctcac    780
tcagcccagc catccatagc cctgggaatt ccacctgcca aggatcccag caggctggat    840
gagggatagt agggcatgag gagaaggagc cctgtaagga ctgaggcccc ggccagccct    900
tctcctccac cagttcccca gagcagagct ggagctgatg cctggacaca gctgctgagc    960
ctggcctggg cctcttamcc acttggttgt tttcttgtcc ctctgtctgt ctgtctatct   1020
acttgtctgt ctgggccact cctgcctgtg tgttggtcta ttcctgggaa gctcatcact   1080
acaggccctg gcaaccttcc cartctgtcc catactgtta cccataaaac tatctcttta   1140
tctgtaaaaa                                                          1150

<210> 328
<211> 1963
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1956)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1958)
<223> n equals a,t,g, or c

<400> 328
aattcggcac gagcagctgg agggcagagg aggcggcgcg gggtgtcctg tcctcgccat     60
gaggccgcag caggcgccgg tgtccggaaa ggtgttcatt cagcgagact acagcagtgg    120
cacacgctgc cagttccaga ccaagttccc tgcggagctg gagaaccgga ttgataggca    180
gcagtttgaa gaaacagttc gaactctaaa taacctttat gcagaagcag agaagctcgg    240
cggccagtca tatctcgaag gttgtttggc ttgtttaaca gcatatacca tcttcctatg    300
catggaaact cattatgaga aggttctgaa gaaagtctcc aaatacattc aagagcagaa    360
tgagaagatc tatgctccac aaggcctcct cctgacagac cctattgagc gaggactgcg    420
agttattgaa attaccattt atgaagacag aggcatgagc agtggaagat aaaccgaaga    480
attaaagatc ccacttccag ccgggcccct catgtatcca ctggccgacc gcagagtgtc    540
cctacctcct ctccagagca tcattccttt ctatctgctg ccagagccac ggtgccattt    600
actccaagga ctcactttct aaaattccac acctggagtg acctctagtc gctcagcatc    660
cactttgtgt ctccaaattg tgtaggactc tgtaatcttt tgattagttt ctgagaaaac    720
acaatgaagc acttcacttt tttttattca aagccattta ataaaacaca gttggtcagc    780
ccagtgcaaa gcttgttatc tgccaccagt acataccatt ggttctcttc attccttggg    840
ccagcttctc aggtggcttt agacctcaac aagccgtatc ttcaccagtg ttctatcttg    900
ttcccctaaa ttaataaaat gtttttctcc aggattttgg tgagggttgg ctgtggctgt    960
cgttttgcac ctcccagatt tcaaagaatt actggtttta ccatgactca aatcttaaga   1020
tctgtttcta ctattcagtt cctcaaactg aagcttattg aaaaaaaaat gtataatgtt   1080
atttgtttta ttatagcaat tattcctaat taaagcagta tttaatgcaa tttccagtta   1140
tttctttgga gaattttatg tcattgttcc attaccttga atgttggaaa gatatgatac   1200
gtgctgcttg ttcatcacaa aaatcagtaa gcacaataaa gtggatgcca aaccatcaga   1260
cacataaatg ttcccgctgt gtccctggat atggaataag caggtataaa aaatatttta   1320
attatagttt tgttataaat ataacttatg agaaaaaaat ttgataggaa taatactgta   1380
tattactaat ttttaactat ccctaaggca aaccttatga cccacagaat tttctcatat   1440
acagtattca gtgcacagaa atcttatgat tggctcaagt acagtaagtt acttctcagt   1500
aaaactctca agtctgagtc catatttgta gctctgcttt tggctgtacg ttcctaggat   1560
cggggctgct tatgcctttc gtttatcctt ggggtttgag agcgctgtat ttgggagaga   1620
gtttaaaaat acattaggag agagaaacca ttaaaagttt cactgtcaga gatattgtag   1680
gtgctaatac tggatttcgt ctcagattta atttctttta tgggtctgtt agtcattcaa   1740
caaatcccat aagtatgtgt taatatttta attgtgtaaa actcatttgt tactttacag   1800
cctgtaatag tgtgtctgca ttttcaacct gttgcaataa ctttgctgaa atattaacac   1860
attaataaaa cttttcttaa acaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaata   1920
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagangngt tta                     1963

<210> 329
<211> 669
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (498)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (522)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (571)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (595)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (604)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<400> 329
aataccacca ctggagagag agccacatgc tgcttcccat catatgtcta cccggaccca     60
acccaggaag aaacataccc gtccaacatt ttatcccatg agcaaagcaa cttctgtaga    120
actgctcatg gagattttgt cttaacttca aaacgtgcgt ctcctaattt attttctgag    180
gcacagtatc aagaagcacc tgtggaaaaa aataatttaa aagaagaaaa ccgtaaccat    240
cctacaggtg agctacttat gtttctctct tctgtgctta tagtgttact aagttgtcct    300
aagatgaagc ctttccatgt tttttcttta aaaattattt tttcagagat ggagtgttgc    360
cgtgttgctc aggctggact caatctcctg ggcacaagta atcttccccc atcagcctct    420
caggtagctg ggactatagg cacgtgctac cctgccagct ctttctgtat ggttattttt    480
ttttgtcccc tgtggcgngt tttttttttt ttgagacagt cncgctctgt cacccaggct    540
ggagagcagt ggcacaatct cagctcactg naacctctgc ctctcgggtt caagngattc    600
ttgngtctca gctactgagg aggctgaagt gggaggattg cttgagccca ggaggcaana    660
ggtttgcag                                                            669

<210> 330
<211> 1144
<212> DNA
<213> Homo sapiens

<400> 330
ccagaactaa gccacccaga caccatcatc ccgaaaaccc cagcccttct cccatggcag     60
attgatcaga ttttgattca ccagaaggct gagcgagtgg aaaatggaag tacaggctcc    120
accaggcacc accattggcc acgtgctaca gacctggcat cccttcctcc ccaagttctc    180
catccaggat gccgatcgcc agacagtctt gcgagtggtg gggccctgct ggacctgtgg    240
ctgtggcaca gacaccaact ttgaggtgaa gactcgggat gaatcccgca gtgtgggccg    300
catcagcaag cagtgggggg gcctggtccg agaagccctc acagatgcag atgactttgg    360
cctacagttc ccgctggacc tggatgtgag ggtgaaggct gtgctgctgg gagccacatt    420
cctcattgac tacatgttct ttgagaagcg aggaggcgct gggccctctg ccatcaccag    480
ttagaggcca ccatggtgtg aggagaccat cacctcgacc agaactccag atggtcacct    540
gccctggccc ctcctctggg cagccccttt cctccatgta cactgcaggg gacagaaggg    600
gggccccatc cctaccctac tccctggccg cctgcccctg tggttcccaa ggaggggtat    660
gtatgagagc cgctctcctg ctacctccca ccactgtccc agcagtccct cggcacacag    720
gcatatcagc tttcacactt tccccatgca ctctctccca cccccttcca gggcctctgc    780
tccaaaggag gcctctggaa cccaggactc tggggtttta caagagggct ggggtgtgga    840
agggcaagct gcaccaaaga cggtggatat agccaccgcc cccccgccgc tgcctagcat    900
ctgcttggcc aattagttca gcctcagacc atggcacttt gagggggtct ctacctcccc    960
atcaacagct gcagggggac cccagtgcca acttcctctc ccactagggc cctgccttca   1020
gctggtgctt gctgcgattc ctgtgcctta tgtaactgcc cttccttccc ttgccctagg   1080
aaaaaggctg catctttata tgttacattc atataaactt tgtaactttt tggaaaaaaa   1140
aaaa                                                                1144

<210> 331
<211> 483
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (387)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (482)
<223> n equals a,t,g, or c

<400> 331
ctctacaagg gagtcccatt tcagrtgtgg ggctgggtat ggtcactcct gctggatgtc     60
tagaaggtga aaaccaagga cctaggaaaa taccagatac agcctttcca ccgtcatcca    120
gagcaggaca aacacgccag gtggtgtcag gagcccaggt ctccagctgg agggaatgtc    180
aaccctgcag tgggagccca tcatgcatcc taggcacaga tgctaacgta ggcaycgcag    240
taagctgggt ttggtacccc ttcctggctt cagaaagaag ccaaacaagg agctttctgc    300
agaatgaaac ctcttttcca tccagaagca ctgctgactg tttggtggtt gctgttaggg    360
cagtgagcct tttgtccatt ctgagantag gctggtttct cctcttgggc ctggcctaca    420
gaccataaaa ggaaaacagc aagaggtccc cagcaaacat ctacagatgg ccctggacat    480
cnc                                                                  483

<210> 332
<211> 1383
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (346)
<223> n equals a,t,g, or c

<400> 332
ctggaccgaa accggcgcgg agcaactgag gcccgagcct tctcgggacc cgggggacgc     60
ctaaccccgc gagatgagga aactgaggcc gcgagagcgc gcatacagca gagaagcagc    120
agaatcggga atcaaaccca gctctgtctg accccagagc ctgtgccttt aaccactggc    180
taggctgaac tgcctttgtt cttcactgtc cccatcacct ctttcaaacc tcagcctctc    240
cttcctcatc gttacatctc taggctgcac ctgctctcta aacattcaca caaaccctgc    300
aaattttctt cctcataatt gggagaagac tcactggccg aatggnagca gtagatgact    360
tgcaatttga agaatttggc aatgcagcca cttctctgac agcaaaccca gatgccacca    420
cagtaaacat tgaggatcct ggtgaaaccc caaaacatca gccaggatcc ccaagaggct    480
caggaagaga agaagatgat gagttactgg gaaatgatga ctctgacaaa actgagttac    540
ttgctggaca gaagaaaagc tcccccttct ggacatttga atactaccaa acattctttg    600
atgtggacac ctaccaggtc tttgacagaa ttaaaggatc tcttttgcca atacccggga    660
aaaactttgt gaggttatat atccgcagca atccagatct ctatggcccc ttttggatat    720
gtgccacgtt ggtctttgcc atagcaatta gtgggaatct ttccaacttc ttgatccatc    780
tggragagaa gacgtaccat tatgtgcccg aattccgaaa agtgtccata gcagctacca    840
tcatctatgc ctatgcctgg ctggttcctc ttgcactctg gggtttcctc atgtggagwa    900
acagcaaagt tatgaacatc gtctcctatt catttctgga gattgtgtgt gtctatggat    960
attccctctt catttatatc cccaccgcaa tactgtggat tatcccccag aaagctgttc   1020
gttggattct agtcatgatt gccctgggca tctcaggatc tctcttggca atgacatttt   1080
ggccagctgt tcgtgaggat aaccgacgcg ttgcattggc cacaattgtg acaattgtgt   1140
tgctccatat gctgctttct gtgggctgct tggcatactt ttttgatgca ccagagatgg   1200
accatctccc aacaactaca gctactccaa accaaacagt tgctgcagcc aagtccagct   1260
aatgaggaaa ttctcttttg ttttttggag catggttctt tgggaagtgg catccactgc   1320
aggaaagcag aatgagcaga gccagcagaa ctgatggagt ggcacaaatt cccagtgtct   1380
gga                                                                 1383

<210> 333
<211> 639
<212> DNA
<213> Homo sapiens

<400> 333
atggaaaagc tcgagctcca ccgtggtggc ggccgctcta gaactagtgg atcccccggg     60
ctgattgccg tcgcaggcgc aaggatatgg gtacaaaacc gtgtcgattt aagccagaac    120
ggtaatttga ttatggtcgc agtaacctta gtgctgggcg cgggtgattt tgctctcacg    180
ctgggcggtt ttacgttggg agggattggt acagcaacct ttggcgcgat tttactcaat    240
gcgttgttaa gcagaaagtt ggttgacgtt ccaccgccag aagttgttca tcaggagcca    300
taaacagaaa accgccgggg ttaccggcgg tgcagattgt tgacaacgta cgcattgttc    360
atgccggatg cggcgtaaac gccttatccg gcctacaaaa cagtgcaaat tcaatatatt    420
gcaatcttct ggtaggcctg ataagcatcg cgcatcaggc aagcttacat ttgtcatcag    480
tatcaaccac cgggtaaccg gcggtgatgg ctttttgacg agctacagac aaaaatgcat    540
tcgtcattga ttagcccggc tagttgtcgc ttttgccgtg actgctctta ccaccttttt    600
tacctgcttc agatgcgcgc tgcgggcccg tacccaatc                           639

<210> 334
<211> 1123
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (277)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1001)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1119)
<223> n equals a,t,g, or c

<400> 334
tttttttttt ttttttaaag gggctgtaat tatatttatt agattaacaa ggcagatgtg     60
aattttctct tctataatcc agtaagtctg tgtattcgtt gactcagaca gacaagaagc    120
cacaaggaaa caaagaagta atcatttgtt gagagacgtt attaactatg atcttccctg    180
aagctaccgg gatgggaaag gtcagtgtct tcctttgaac cctgagacaa ttaggggctc    240
ttgaggcctg ctgtgcccct gctgccaagg cagcctncaa gttcaaggag cagctaatca    300
cccactcctg cattcagtct gtcttgcctg atgagggcta cgcaggctgc ctcccattgg    360
tgtgcactgt ttcctttttc agctgctaaa tggctgaaca ccatcggcct ggggtatccc    420
tttttgggga atacgtctgt ctgtctgaac tcctttccct tcaaatggca ctgtgataaa    480
atctggtcat accatgctcc agcatggaag tacatgaaag cacgcagtct gtgagtgccc    540
atgaggactc tcgtgctggc ccccgtggcc ctggctagct gtcgtaccag tcgaggaaga    600
gcaaggagaa ggagcacatc acgaggaaga agaggatcca cacgcggaag ccagcgttgt    660
ttttaatggc ctctcttatg tcytcgttgc cttccttgat attttyagtt gcccccacaa    720
ctaactggtg aatgctgtya atctcagctt cctgttgcaa aaccttttcc gtgaatatct    780
cttggagtct ggaaatctca accactctcc cttcgatttg cctcacttca tcaaacaagc    840
tgttcatttc accaattagt cgctgatttt cctgttcaaa catttgtatt tcttctgggg    900
ataactcatc ttcgcctttg ccatctcccc acgttcccaa ttcaggttgt gtttcagcca    960
aaattttttc tggacgttct tcagtggcag ggttttcttc ngagtctttt gaaggactct   1020
gtgaaacttt ctcagaagat gtggattctc ttgtctttgt atttggttct ggttccagct   1080
tagataatct ttttccccac gcgtccgcgg acgcgtggnt cga                     1123

<210> 335
<211> 497
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (65)
<223> n equals a,t,g, or c

<400> 335
tcagcataag ggggaggtga gagtgaaagt ttcatcgcgg cctcacttgg cgatatgcgc     60
aattntggcg atttccacca gcgcgtcagg ttttaccagt ccgcactgaa tgcagaatcg    120
cgccggtwta tcacccggaa aaaactcggc gtagatttcg ttaatcgcgg cgtaattttt    180
ccagtcggta ataaagatgc tgttgaaggt cacatccgcc atcgtgccac ccgccgtctc    240
gatcaccttg cggatagttt ccagaacgtg gcgggtttgc gcctttgggt catcggcaaa    300
cagcacgtta ttatgttgat caaaagccag cgtaccggag acatacacca cgccatcagc    360
cagcgtgccg ggaacgaagg gggccagcgg tgcctgctgc cagcgggaat aattacggat    420
tttggcatcg ttaaactcct taagcgatat gagcaaagga cgtgggagaa aagcgcgtcg    480
cagaatgttt cgacgtc                                                   497

<210> 336
<211> 996
<212> DNA
<213> Homo sapiens

<400> 336
ggcacgagcc aagtttgtcc agtcacgaaa tcagcaggaa gtgatctata acacccagag     60
cctcctcagc ctcctggttc actgctgcag tgccccaggg ggcactgaat gtggggaatg    120
ctggggggca cccatcttga gtccagaggc agccaaagca gtggcagtga ccttggtgga    180
gagtgtgtgt cccgatgcag ctggtgcaga gctggcctgg ccccccgagg aacacgcccg    240
ggccaccgtg gagcggggat ctccgcattg gccggcgctt ccgcgaacag cccctgctct    300
ttgagctgtt aaagctggta gcagctgcac ccccagccct gtgctactgt tccgtgctgc    360
ttcgggggct gctggccgcc ctcttgggcc attgggaagc ctctcgccac cctgacacga    420
cccactcccc ctggcacctg gaggcatcct gcaccttagt ggctgtcatg gctgagggaa    480
gcctcctgcc tccggccctg ggtaatatgc atgaagtatt tagccaactg gcacctttcg    540
aggtgcgtct gctgctgctc agtgtctggg gttttctccg ggagcatggg cccttgcctc    600
agaagttcat cttccaatca gagcggggtc gcttcattcg ggacttctcc agggagggtg    660
gaggtgaggg tggaccccat ctggctgtgc tgcacagtgt cctccaccgc aacatcgacc    720
gcctaggtct tttctctggc cgtttccagg caccttcacc gtccactctc cttcgacagg    780
ggacgtagcc ttttcttgct ctggaagccc agggaggttg agcagtgaga gagggaaggg    840
actaacgtgc tccggaaggg tggaggtttc tcttctaagt ccttggtcta aagagcgctg    900
tcactttttt ctctcccact tttttttttc taaataaaat ttgccaactt gaaaaaaaaa    960
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                              996

<210> 337
<211> 2520
<212> DNA
<213> Homo sapiens

<400> 337
acttttcttt cttcattagg aaatcttatt gcacaggaac cacccccacc cccacccccc     60
acaccttccc aaggcagcat cccagtgaga tagagtggga aaggtcccag agggctcact    120
cacctctagg cccagagagg ctttctcctc actttataca ctgcaaaaac agaagaattg    180
tgtcaataac accctctgta gtggagaaac ttaaaaagct ggttaggaag ctctcgtgta    240
tatttagaga caattacaag aaagctggac ttgccgctgt ggtctcagga gaaatgagtg    300
ttcttgatga caggcaaagg gacatcttag ttgtccagaa gcggcactct tccctggaag    360
ccgccatgtt aataggatta ctaagcctgg ctccagacag tgcctgctca tggctgccag    420
ttcttaccga tcacatctgt cactgccacc gtatatcatc tgccagtgca tcagcttaag    480
gggaggtcac gagtgcaaaa gaacctgacc cttgacaatg agggagaagg gacatggacc    540
acctgtctgg gaattcctgg gaatcactgg cagggtggag gctgggctgg ggattagccg    600
cggtgtgcgt gaatggctct gtctccagca agtctctctc catcaaaccc caggtctgcc    660
ccataagcaa gatctttaac agatggatgt ctccatgagg aaaacccaag gcgagaagcc    720
caagccatgg cggggttgct tgacgtcctc atggagtcac tctgccccac atgctcaaat    780
cttccctctg gccccacatc cctaggaggg cctgacccct gtaaagatac aggaggcagc    840
tccctggcct ccaaatggcc catggagatg gcagtcggga gacagggttc tgtgtttgct    900
gcggtgaagg gaggagaagg caggaggaaa aaggatggct tctagccctg aagaggactc    960
cagcatccca ggcaccgggt gcttctggct gcagttttcc ctatggaggc ccctcagcct   1020
ccagccctaa cataaatgtc ggttaaattc agttttcaag cctctctccc ttttcagtgt   1080
cagagcagta gatggtccag ggcattggag gcctcgacca ctctgcattg cagattacag   1140
tgacttcctc ggggttgccc catcttggtc tcctgtggtt tcttcatcag cttttttttt   1200
accagcatct ctcaaataac aatgaaagat agatatgccc attaatgtct gattaaggag   1260
caaaggctgg atttctggcc acagcgcgct gcactctccc tcctgcctca gccggggtcc   1320
gtcttagcag tttggaaagg ggaaaaagat gccggtcctc actgcttaag ttttgtgtcc   1380
aggcggccgc tcagaactag tggatccccc gggactgcag gacattcggc acgacctcgt   1440
gccgcgcccc actgcacaga tgaggaacca gaggctcaga ggagtgaagt tgccttcctg   1500
aggtcacaca gcatgaaagt gatgagctag gatttgaatc tgggaagttg ggctctagag   1560
ccagactgta ctgccttctg ccacactgta ctgccttctg tgactgggtg gcacctccag   1620
ggcacattta cacaaggccc tgaatctgca gaggctgttt ctcaagatgc ccgtcatggt   1680
gtggcctggg ccagctctgg cttccacagg tccctgactg tcctcagagt ggaacatgct   1740
caacctcccg cccactgctc tctcttctgc ccagatttca ggggtgccgg tccccaaggc   1800
ctgccccctt tctttaagac tgaactcaag tctccttgga aggccccggt gaagctccca   1860
gagactggtt ttcttgggat gcaggcagaa ggggaccctc cctggccaac acccaggagc   1920
ccagcagaag cacccacacg tagaaagagg ctcactacag ccagaagtgc agagtcagag   1980
tcctgggacc atcttgttct gcaaggtgac cccaggctcc ccaggacagg ggagagggat   2040
cgtcctcatt cagactctag ctggggcctc tgtactggct tctccctggg tggggttgcc   2100
tgttacatag ctgtgcctca gagaaagggt cctgcatttt ctggaatgtt ctctgtgctt   2160
acccctctgt gtgcccctcc attgctcctc tacaagcaat taggtgattc aaaagagcaa   2220
cttaggctgg gtgcagtgac tcacacccgt aatcccggca ctttgggagg ccgaggcggg   2280
cagggacagg agttcaagac cagcctggcc aacatggtga aaccctgtct ctacaaaaaa   2340
tacaaaaatt aaccagacat tgtggcatgt gcctgtaatc ccagctactc aggaggctga   2400
cacaggagaa ttgcttgaac caggaggcgg aggctgcagt gagctgagat tgtgccactg   2460
cactccagcc tgggcaacag aacgagactc tgtctcaaaa aaaaaaaaaa aaaaaaaaaa   2520

<210> 338
<211> 767
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (634)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (679)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (681)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (697)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<400> 338
gacagattgt ctctccctct ctctctcaca cacacacata gaaaatcact gcacatattc     60
tctttctcta aatagttaag ttttatgtat tcttgaagca taaaatgtgt ccctttaaat    120
ggattctccc atttctttta aatttcctaa aataaaaaag attcccacta tgtatggact    180
tctttgtcag ttcctgccac tgcactccca gctgtggcta ctgaagagct cccagcagat    240
tgctcagctt tgcctaatgc ctgaatcatt aagattcagg cccggtggta tattggaaac    300
taattctcca ccagcaggaa taagaaaatt agtctgtagc cccatgccag gtgtctcttc    360
tcccaaggac tacatcagct tcaagctaag ctttctttct ctaaccaccc tcccccttct    420
tccctctgca tttctattcc attcttctga gctgcctgcc ctcctgggcc ccttgtaata    480
aacctcaacc acaaggtaag ttttctaggg ctctcccctc cttcctgctc ccgcaggtct    540
cttccttcag ggtctagttc ctactctttg catcctcggc taccggctgc ggctctgctt    600
taatccccgt ggaacttcct gacagcatgg gttnagttcc ttacctaagg cagatactaa    660
acccaatccc tggttgganc nttcttggct tttcttncct ttaaggcaga accttttggg    720
aaaaccngga atctaagccc tggaaggaat ttcactgggg gttacca                  767

<210> 339
<211> 1212
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1148)
<223> n equals a,t,g, or c

<400> 339
cggccatctt ggaggctgag gcggcggcgg cggcgctgcg gcgggttcgg tgggcccaat     60
cccggggcgg tgcggctgtt tcgggcgcgg gccccgcttt tccgcaccct gctccggcct    120
cgactacggc gagcctgagc gcggcggcgg cccacgcgca gcacagggag agatgagcag    180
caccagcagt aagagggctc cgaccacggc aacccagagg ctgaagcagg actaccttcg    240
cattaagaaa gacccggtgc cttacatctg tgccgagccc ctcccttcga atattctcga    300
gtggcactat gtcgtccgag gcccagagat gaccccttat gaaggtggct attatcatgg    360
aaaactaatt tttcccagag aatttccttt caaacctccc agtatctata tgatcactcc    420
caacgggagg tttaagtgca acaccaggct gtgtctttct atcacggatt tccacccgga    480
cacgtggaac ccggcctggt ctgtctccac catcctgact gggctcctga gcttcatggt    540
ggagaagggc cccaccctgg gcagtataga gacgtcggac ttcacgaaaa gacaactggc    600
agtgcagagt ttagcattta atttgaaaga taaagtcttt tgtgaattat ttcctgaagt    660
cgtggaggag attaaacaaa aacagaaagc acaagacgaa ctcagtagca gaccccagac    720
tctccccttg ccagacgtgg ttccagacgg ggagacgcac ctcgtccaga acgggattca    780
gctgctcaac gggcatgcgc cgggggccgt cccaaacctc gcagggctcc agcaggccaa    840
ccggcaccac ggactcctgg gtggcgccct ggcgaacttg tttgtgatag ttgggtttgc    900
agcctttgct tacacggtca agtacgtgyt gaggagcatc gcscaggagt gaggcccagg    960
cgccgagacc caaggcgcca ctgagggcac cgcgcaccag agcgtgacct cggcaggctg   1020
gacacactgc ccagcacagg cagacccacc aggctcctag gtttagcttt taaaaacctg   1080
aaaggggaag caaaaaccaa aatgtgtgac tggctttgga ggagactgga gcctcaccct   1140
tgtcctgnca cggccgctgg ggctgtgtgg tgggccttgg gtgctggatt ggacttattt   1200
ccgggtgctt tg                                                       1212

<210> 340
<211> 820
<212> DNA
<213> Homo sapiens

<400> 340
ggtctgcgcc ggaagtgcat gagctgccga tgtggtgctt agtgattgcg gtttcggtcg     60
ctctcccgtg tttcccgggc tgggtatttg cctcgcacca tggcgcccaa gggcaaagcg    120
ggcacgagag ggaagaagca gatatttgaa gagaacagag agactctgaa gttctacctg    180
cggatcatac tgggggccaa tgccatttac tgccttgtga cgttggtctt cttttactca    240
tctgcctcat tttgggcctg gttggccctg ggctttagtc tggcagtgta tggggccagc    300
taccactcta tgagctcgat ggcacgagca gcgttctctg aggatggggc cctgatggat    360
ggtggcatgg acctcaacat ggagcagggc atggcagagc accttaagga tgtgatccta    420
ctgacagcca tcgtgcaggt gctcagctgc ttctctctct atgtctggtc cttctggctt    480
ctggctccag gccgggccct ttacctcctg tgggtgaatg tgctgggccc ctggttcact    540
gcagacagtg gcaccccagc accagagcac aatgagaaac ggcagcgccg acaggagcgg    600
cggcagatga agcggttata gccattgaca ttgtggccac aggccactgg ccctgggtgg    660
ctctgtcagg gtgcacagcc cctcatgcct ggagcaatga gggtctagtc caggggccaa    720
aagcagtctg aggtattggg tatacttata ctctataggg tcgttgaata aatggcttag    780
aatgtgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                          820

<210> 341
<211> 1984
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (198)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (253)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1962)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1984)
<223> n equals a,t,g, or c

<400> 341
ggtgaccgcc atcaacagtc agaaagctgt gctcagcact gatgtgcaga acacaccagt     60
caacctccag acgtctagta aggtcactgg gcctggggca gangctgtcc aaattgtggc    120
aaaaaacaca gtcactctgc aggttcaggc aacacctcct cagcccatca aagtaccaca    180
gtttatcccc cctcctanac tcactccacg tccaaacttt cttccacagg ttcgacccaa    240
gcctgtggcc canaataaca ttcctattgc cccagcatca cctcccatgc tcgcagctcc    300
tcagcttatc cagaagcccg tcatgctgaa caagttcacc ccacaaccct tcccacatcc    360
cagaattcca tccaccccgt ccgtgtcgtc aatgggcaga ctgcaaccat agccaaaacg    420
ttccccatgg cccagctcac cagcattgtg atagctactc cagggaccag actcgctgga    480
cctcaaactg tacagcttag caagccaagt cttgaaaaac agacagttaa atctcacaca    540
gaaacagatg agaaacaaac agagagccgc accatcaccc cacctgctgc acccaaacca    600
aaacgggagg agaaccctca gaaacttgcc ttcatggtgt ctctagggtt ggtaacacat    660
gaccatctag aagaaatcca aagcaagagg caagagcgaa aaagaagaac aacagcaaat    720
ccggtctaca gtggagcagt ctttgagcca gagcgttaag aagagtgcag tgacatacct    780
aaacagcaca atgcaccctg ggacccggaa gagaggtcgt cctccaaaat acaatgcagt    840
gytggggttt ggagccctta ccccaacatc cccccaatcc agtcatcctg actcccctga    900
aaatgaaaag acagrgacca cattcacttt ccctgcacct gttcagcctg tgtccctgcc    960
cagccccamc tccacagacg gtgrtattca tgaggmtttt tgcagcgttt gcagaaaaag   1020
tggccagtta ctgatgtgcg acacatgttc ccgtgtatat catttggact gcttagaccc   1080
ccctctgaaa acaattccca agggcatgtg gatctgtccc agatgtcagg accagatgct   1140
gaagaaggaa gaagcaattc catggcctgg aactttagca attgttcatt cctatattgc   1200
ctacaaagca gcaaaagaag aagagaaaca gaagttactt aaatggagtt cagatttaaa   1260
acaagaacga gaacaactag agcaaaaggt gaaacagctc agcaattcca taagtaaatg   1320
catggaaatg aagaacacca tcctggcccg gcagaaggag atgcacagct ccctggagaa   1380
ggtaaaacag ctgattcgcc tcatccacgg catcgacctc tccaaacctg tagactctga   1440
ggccactgtg gggccatctc caatggcccg gactgcaccc cccctgccaa tgccgccacc   1500
tccacgccgg ccccttcccc ctcctcccag agctgcacag cgaactgtaa ccagggggaa   1560
gagactaaat aacagagccc ctctaggaga agccacggga tcccggcggc aaggagaaca   1620
gaacactgaa gactctagaa aagcaaagcc ggatttctgg aaagtgcaga attcttttgg   1680
ttctttggtt ccagagagag agaagatgct tgtgccaggt ggcaccagag tttgccaatt   1740
gatccttctt attctgtgtg tacatgcaaa gattggacca tgttacatga aatagtgcca   1800
gctggaggtt ctttgccagc accatgccaa gtgaaataat atatttactc tctctattat   1860
acaccagtgt gtgcctgcag cagcctccac agccacgatg ggtttgtttc tgttttcytg   1920
ggtggggaac caggggacgg gccggaaggg aaggagaagc anggtttcaa gattccttaa   1980
cttn                                                                1984

<210> 342
<211> 680
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (607)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (636)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (643)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (665)
<223> n equals a,t,g, or c

<400> 342
ggggggcttt ctcccaccgc tttccgagcc cgcttgcacc tcggcgatcc ccgactccct     60
tctttatggc gtcgctcctg tgctgtgggc cgaagctggc cgcctgcngc atcgtcctca    120
gcgcctgggg agtgatcatg ttgtaatcca cccaccgcca cttcaagaag aaatgatatg    180
aagaagtgcc ggttctccct cccctcttcc gcactgtccc gtgaatgatg acgcctccag    240
agaggacgat aatctgggtt cctgggagag atggcttggt cactattccc acccttgcct    300
cgaccacttg tctcaatgtc accacctcac gccctgttcc agataatgct cggaatattt    360
ttcaatgtcc attccgctgt gttgattgag gacgttccct tcacggagaa agattttgag    420
aatggccccc agaacatata caacctttac gagcaagtca gctacaactg tttcatcgct    480
gcaggccttt acctcctcct cggaggcttc tctttctgcc aagttcggct caataagcgc    540
aagggaatac atgggtgcgc taggggcccc ggcggcgttt tccccgctcc agcccctcct    600
ttatttnaaa ggaytccctg gcaccgtgtt cacccngggt cgngttccca ccctttgccg    660
ggcgnctttg tggggattgg                                                680

<210> 343
<211> 1322
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1086)
<223> n equals a,t,g, or c

<400> 343
gctgaagatg gggtccctcg cacggcacgg tccatgtccc tcacgctggg aaagaatatg     60
cctcgccgga ggtcagcgtt gctgtggttc ctaagtttaa tgccctgaat ctgcctggcc    120
aaactcccag ctcatcatcc attccctcct taccagcctt gtcggaatca cccaatggga    180
aaggcagcct acctgtcact tcagcactgc ctgcactttt ggaaaatgga aagacaaatg    240
gggacccaga ttgtgaagcc tctgctcctg cgctgaccct gagctgcctg gaggagctta    300
gtcaggagac caaggccagg atggaggaag aagcctacag caagggattc caagaaggtc    360
taaagaagac caaagaactt caagacctga aggaggagga ggaagaacag aagagtgaga    420
gtcctgagga acctgaagag gtagaagaaa ctgaggaaga ggaaaagggc ccaagaagca    480
gcaaacttga agaattggtc catttcttac aagtcatgta tcccaaactg tgtcagcact    540
ggcaagtgat ctggatgatg gctgcagtga tgctggtctt gactgttgtg ctggggctct    600
acaattccta taactcttgt gcagagcagg ctgatgggcc ccttggaaga tccacttgct    660
cggcagcccc agggactcct ggtggagctc aggactccag catgagcagc ctacagagca    720
gtaggaaacc tcacacctag ccagtgccct gctctgagac actcagacta ccaccctttc    780
cccaagtata acgtcaggcc caagtgtgga cacactgccg cccatcccat caggtcatga    840
ggaagggttc ttttaacact cggcacttct gtgggagcta ttcatacaca gtgacttgat    900
gttcttggag gatcaacaaa actgccctgg gaaagcatcc agtggatgaa gaagtcacct    960
tcaccaagga actctattgg aagggaaggt ctcctgcccc tagctcaggt ggctggggag   1020
aactaaaaca ccttcactgg tggttggggg taaggagcgg ggcacggggg aggaggaggt   1080
aggggncagt aaaaaactta ctctcttttt tcctctctgt aattggttat caggaagaat   1140
ttgcttaatg actaacaccc taagcatcag acctggaatt tggagttgca aagtgactat   1200
cttcccattt cccatctcat tttcaataac ttcagcctcc cattctttcc tttggaatga   1260
gagtttcttt ttacagaagt aggaaaggct tctcagaaaa aaaaaaaaaa aaaaaaactc   1320
ga                                                                  1322

<210> 344
<211> 702
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (663)
<223> n equals a,t,g, or c

<400> 344
acctgttaaa atgcaaagca aatttctttg gggcagaaaa acaatctgac agtagcagtg     60
tagaatttgt tcattcaaat acatctgtgt aaatgcaaaa agtcataaaa ttcacctccg    120
agctgcttgc ttttgaacct gcagcaacta gtcttagccg gcccggtttg aacatcgttc    180
tttcagaagt gctgaaaatg ctgcaaagtt ggataagtgg aaatgtggct gcccctctcc    240
tcactacttc ctctctgatc gtwctgaagc ttgcattggg aatggctgct ttctctaacc    300
attttcagct tgagtgggta ttgctgaaga aatccaacat cattccagca gttgaaaaag    360
gaagccttcg ggagaaagtg cttgcaaaat tttgtctttg tgcttgkgta tgagtaagtt    420
gccatgaata agttattatt ttaacccata attggcgact gtttatatga attctttctt    480
tggcaccaaa taggtttcat cttcttaggc acaattagaa aaaatccaca tagatggata    540
ttttacattt agttattgct ttatccaaat acatgaatct aaagctgaat caacccttac    600
ttccagttgt gcttattaag aagatcaatt tccaagtagt aaagtttcag gggaactgac    660
tgngctgcta ttgggtttga ccaaattggg ggggaaatcc at                       702

<210> 345
<211> 494
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (458)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (493)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (494)
<223> n equals a,t,g, or c

<400> 345
gccacattgt cttccccaga agctcaaact ggatgcccag ccctcagtgt acaaactcaa     60
gtatgcaaga aatacatctt tattctttta tgaatatacc taatttatat gttggaaggt    120
gtcagcaatg aatttgatca ctttggtatt tctctacctt taaagatatg tttacatttg    180
gggtgggatg aaggtttggt ggaggggaag gtggtcaggt tgggccaagg tattgggaaa    240
tccatttgtt cctcatgtca gctgtttgag gaggcaccaa cccagatgtc cacagttcct    300
tctggccttc ctttaccgat actgatgcac ctgtgcctcc ttcctgtgtg catggcccat    360
ttgtgcccag catctccctg ctattttggg gccactccag ggtctgggaa gttctgtagg    420
cttataacat acagtcattc ttctccccag cttgctgnct cctgagacac agaggtagag    480
aagtaggaaa ggnn                                                      494

<210> 346
<211> 2230
<212> DNA
<213> Homo sapiens

<400> 346
ttgtactctc tctgataatt ttcctgacca cactatttta tctattaagt tccagtgatg     60
agtactacaa gccagtgaag tgggtgataa gcctgactcc actatctcag ccaggtcctt    120
cttctaatat tattggccag tctgtggaag aagctatcag aggggtgttt gatgcttccc    180
tcaaaatggc tggcttctat ggattgtata cctggctgac tcatactatg tttggcatca    240
atattgtctt cataccatca gcattagcag caatccttgg agcagtgcca ttcctgggga    300
catactgggc agcagtacct gcagttcttg acctgtggct gacacaaggg ttaggatgca    360
aggccatttt actgttgatt tttcatctct tgccaacata ctttgtagat actgcaatct    420
actctgacat atcaggaggt ggccatcctt acctgacagg cttggcagtg gccggtggag    480
catactacct aggcctggaa ggagcaatca tcggtcctat tcttctctgc atacttgtgg    540
ttgcttccaa tatctatagt gccatgctag tgagtcccac gaattcagtt cccacgccaa    600
accagacccc atggcctgct cagcctcagc ggactttccg tgacatttct gaagatctga    660
aatcttcagt aggttgatgt ggtttcctct gcagtgattt ttctaggaag ttcaaatttg    720
acagcgagtt cagctcagct gtggccytct gcccttccag ctgtgcctag caagcaaaac    780
ccaggaaaga agcagaagcc tcctggcctt acatacagaa tgcctggaca agagagaact    840
tgctgcgggc tgctttgtat tttaaaacac agcttgagag ttcagmgttg gtggtttgct    900
cacttaactg ttgttaagat ggcttgaaaa gtttcatttt atacactggt accctggctt    960
gaaatttttc cactttggtt atctatgtta ctatattata tatttataaa gttattttaa   1020
gaactctaaa ctacctgctg ttaaaagaat agatggtgta attttttcct ggtttaagaa   1080
atgtattgtt aaacttttct aagacagtca cttttcaagg aagagggctt tcacttttga   1140
gtgtgtagtt gagtgagcag gaaaaatgaa tcttctaccc ttctcccaca atgtattata   1200
cgctctttaa gaaataataa atcataagta taagggtggg gtggcttatt tgatgttcag   1260
ttttatatta taaccctggg agatacaaag actgaagctc ttcctcctct tccttttctc   1320
ttcacgcttc tttacactat tgccaaatta taaaacttgg ctgaccacgt tgaagtgaaa   1380
tacttattaa gctgctatga atggtaacag tatgataaaa ttcatgctgt tattaggttt   1440
tctccttcca ggtggttgaa gtgaaaaatc tcaggtgtag caatactctg atttgttaaa   1500
tgtatccgtt tcattatttg gaactctgcc aataagttag ttttcagcag aattttgtat   1560
ttatgtagta ttttcccatc tcttagcaca gtgccttgca catgactcta aatgaatgct   1620
tgttgaattg aattgcaact ttaaaaatat ctcagatatc acaataacca gcatagtgct   1680
ttacatttta caaagtcctt ttgcacatac tatttcacaa gtacatcaca tcagctttca   1740
tatagcttta tattatttta catcagtttt acactgatgg agaagctaag gttcagaaaa   1800
gtgaccaact caaagtcgta aagtgtagta ggatttggcc tcagatcttt gactccgttg   1860
tgtgcagatt ctgctgtatt agtgttcctt ctaaatattg tatgcagttt tcccagtgtt   1920
acgagattgg tgttgctatc catttgttgt gaatgaagac ttgtcctata gtacatgaca   1980
gggctgagag tggactgtag ttcttagctg aaccctttct actgtttaaa acaatcatca   2040
ggcctatcct ctgctcccag gggaatgtgg gagagaaaag ggttcttggc caggctgtag   2100
gtggtggctc acatctgtaa tcccagcact ttggaaggct gaggtgggtg gattgcttga   2160
gcccagggat ttgagatcag cctaggcaca tggcaaaacc ccatcttctt acaaaaaaaa   2220
aaaaaaaaac                                                          2230

<210> 347
<211> 586
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (492)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (504)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (533)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (569)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (574)
<223> n equals a,t,g, or c

<400> 347
gagacaggcc gctggctgag gcccggctcg tgtccctgca gggcatggcg ggtcagttcc     60
gcagctacgt gtgggacccg ctgctgatcc tgtcgcagat cgtcctcatg cagaccgtgt    120
attacggctc gctgggcctg tggctggcgc tggtggacgg gctagtgcga agcagcccct    180
cgctggacca gatgttcgac gccgagatcc tgggcttttc cacccctcca ggccggctct    240
ccatgatgtc cttcatcctc aacgccctca cctgtgccct gggcttgctg tacttcatcc    300
ggcgaggaaa gcagtgtctg gatttcactg tcactgtcca tttctttcac ctyctgggct    360
gctggttcta cagctyccgt ttcccctcgg cgctgacctg gtggctggtc caagccgtgt    420
gcattgactc atggctggca tcggggagta cctgtgcatg cggacggagc tcaaggagat    480
accccttaac tnaagcccta aatncaatgt ctagaatcag ccctttggac atnctgctga    540
cacttgggcc ccttaacacc ttgggctgnt taanaccttc agatga                   586

<210> 348
<211> 485
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (401)
<223> n equals a,t,g, or c

<400> 348
ggcacgagcc tgcttgaagc ctaactgtcc accagaaagg actgctcttt gggtgagttg     60
aacttcttcc attatagaaa gaattgaagg ctgagaaact cagctgctna tcatgtggaa    120
cagctctgac gccaacttct cctgctacca tgagtctgtg ctgggctatc gttatgttgc    180
agttagctgg ggggtggtgg tggctgtgac aggcaccgtg ggcaatgtgc tcaccctact    240
ggccttggcc atccagccca agctccgtac ccgattcaac ctgctcatag ccaacctcac    300
actggctgat ctcctctact gcacgctcct tcagcccttc tctgtggaca cctacctcca    360
cctgcamtgg cgcaccggtg ccaccttctg cagggtattt nggctcctcc tttttgcctc    420
caattctgtc tccatcctga ccctctgctc atcgcactgg gacgctaact cctcattgcc    480
caacc                                                                485

<210> 349
<211> 1115
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (467)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1055)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1090)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1112)
<223> n equals a,t,g, or c

<400> 349
taagatgcct ggcctggatg tttattttgc cgctgatgtt tgttacgccg agaaagttgc     60
gcaagaaaaa ggttttttat atcgtttaac atcacgatat cgccattatg ccgcatttga    120
gcgagcgact ttcgagcagg gtaaatcgac gaaacttatg atgctgaccg ataagcaaat    180
cgccgatttc cagaagcatt atcaaactga acctgaacgt tttcaaattc ttcctcccgg    240
tatttatccg gacagaaaat acagtgagca aatcccaaac agccgtgaaa tttatcgcca    300
gaaaaatggc ataaaagagc macaaaactt attactgcag gttggatcag attttggccg    360
taaaggtgta gatcgctcaa ttgaagcttt ggcatcgtta ccggaatcat tacgtcacaa    420
tacgctttta tttgttgttg gtcaggataa gccgcgaaaa tttgaancgc tggcagaaaa    480
actcggcgtg cggagcaatg tgcatttctt ctccggtcgc aatgatgtgt cagaattaat    540
ggcagccgct gatttattac tgcatcccgc ttatcasgaa gccgcgggta tcgttcttct    600
agaagcgatc actgctgggt tacctgtttt aacaacagcg gtatgtgggt acgcgcatta    660
tattgcggat gccaattgtg gaacggtcat cgctgaacct ttctctyagg aacaattaaa    720
tgaagtttta cgtaaagcgt taactcagtc gccattgcga atggcctggg cggagaatgc    780
tcgccattat gccgatactc aggatttgta tagcttgcca gaaaaagccg cggatatcat    840
tacaggtggt ttagatggtt gaattaaaag agccgsttgc cacactttgg cgtggtaaag    900
atgcttttgc agaggtcaaa aaactgaacg gcgaggtctt tcgtgaactg gagactcggc    960
ggacattacg ctttgaactg ccgggaaaag ctattttctt aaatggcaca aggggacgac   1020
attaaaagag attataaaaa atctactctc attgnggatg cccggtttgg gccgcaagac   1080
agagagtggn acgctattca tcggcctgga gngga                              1115

<210> 350
<211> 357
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (314)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (331)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (342)
<223> n equals a,t,g, or c

<400> 350
caggtctcgc cgcccgcttg atccctgagg tgtttccatg ctgcgggtgg tgcttccagg     60
cagagtgggt gggggcccac cgggcaccgc cctttcttcc ttgtccctgc ctcactctga    120
gagccttggg ggtctccacc agtgcagaca agggctacag tctccagggc cgggtcttgt    180
ccctcttctc cgctggtcca cgctggcagc tcttggcttc gggcctgcct tctgcctccc    240
tttgggatct gtgtcttcca gggatcagct gcttggcttt gctggaggtg cctcctgtgg    300
gggcgcactg cctnctgctc taagttcttg ncagagctgc tncccttcct tgcttgg       357

<210> 351
<211> 1488
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (83)
<223> n equals a,t,g, or c

<400> 351
acatgtcccc tggggacccc angtggctgg acgtgattga gcgtgacctg caccggcagt     60
tcccattcca tgagatgttt gtntcccggg ggggccacgg ccagcaggac ctattccgtg    120
tgctgaaggc ctacacgctg taccggcccg aggagggcta ctgccaggcc caggcgccca    180
ttgccgctgt yttgctcatg catatgcctg ctgagcaagc cttctggtgc ctggtacaga    240
tctgtgagaa gtacctgccc ggctactaca gcgagaaact ggaggcgatc cagctggacg    300
gggagatcct tttctcgctg ttgcagaagg tgtcgccggt ggcccacaag cacctcagcc    360
gtcagaagat cgacccgctc ctytatatga cagaatggtt catgtgcgcc ttctcccgaa    420
ccttgccctg gagctctgtg ctgcgtgtct gggacatgtt cttctgtgaa ggggtcaaga    480
tcatcttccg ggtggggctg gtgctgctga agcacgcgct gggctcccct gagaaggtca    540
aagcctgcca gggccagtac gagaccatyg agcgactgcg gagcctcagc cccaagatca    600
tgcaggaggc ctttctggtc caggaggtgg tggagttgcc cgtgacagag cgccagattg    660
agcgcgaaca cctcattcag ctgcggcgct ggcaggagac ccggggtgag ctgcagtgcc    720
gctccccgcc caggctgcat ggtgccaagg ctatcttgga tgcagaacct ggtccccggc    780
ctgccctaca accttcacca tccatccgcc tgcccctaga tgcccccctc cctggctcca    840
aagccaagcc caagccaccc aagcaggccc agaaggagca gcggaaacag atgaagggga    900
gagggcagct ggagaagccc ccagccccaa atcaagccat ggtggtggcc gctgcaggag    960
atgcatgtcc cccacagcat gtgcccccga aggactcagc ccccaaggac tcagcccctc   1020
aggatttggc tccccaggtc tcagcccacc accgctccca ggagagyttg acgtcccaag   1080
agagtgagga cacctacttg taamcctggc agctaaggcc tccagggcgg ggtctccata   1140
taactacacg gttcatgaac tgacattcca catcctgccc accctctgag ggccaagctg   1200
cctggccact gggctgggct ggagtctggc tggtccaaca cagattctgc ctggtccaac   1260
acagattctg cctgagcctc cttatttatt ttctttacag tggcactcag gctgcccagc   1320
cagggcaggc agaagctagg gcctgggggg tggggcctcc ttcagccccc tcctcctggg   1380
gatgctcccc agggttaggg tgctggtgtg aggggaaagg gtggggtgtt ctttgtgtaa   1440
aatagaaaca tggttttgta cagaaataaa cagccttgta taragaaa                1488

<210> 352
<211> 781
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (405)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (747)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (767)
<223> n equals a,t,g, or c

<400> 352
cggacgcgtg ggncggacgc gtgggcgaaa cactgtccct gcgagttctt taagttccct     60
gcaatctgta cacaagagaa agagggagag agagagggag agagacagag agagcaggga    120
tcaggtaaag gagtggggct gctgcagcca ttcagacctc aggagctgga aaattgccaa    180
ggatgcagaa ggaaatgaag atgatcaaag acgaggatgt gcatttcgac ttggctgtga    240
agaagacccc ctcctttccc cactgcctgc agccagtggc ttctcgggga aaggctcccc    300
aaagacaccc cttcccggaa gctctccgag ggccattttc ccagtttcgg tatgaacctc    360
ccccaggaga cctagatggg ttccccgggg tcttcgaagg agcanggtct aggaaacgga    420
agagcatgcc cacaaagatg ccctataacc accctgcaga agaagtcacc ctcgccctcc    480
actcagagga gaacaaaaac cacggccttc ccaacctccc tttgctgttc ccgcagcccc    540
cgcgccccaa gtatgactct cagatgatcg acctgtgcaa gtgggcttcc aattctaccg    600
cagcctggga acactttggg ggcaagcccg tcaagcagga acccattaag cccagcgccg    660
tgtggcccca gccaacgccc aytccattcc tgcccacgcc ytamccctat tamcccaaat    720
tccaccnggg cttcatgttt ccccttnttt gtggccttgt tcttggnctt tccctttcaa    780
c                                                                    781

<210> 353
<211> 671
<212> DNA
<213> Homo sapiens

<400> 353
gcctatctca gagtcgtggc ccacaggtga ccagcctctc agggaaagag tatgatgtgc     60
tctacctggg gacatgagga tggacacctc caccgagcag tgcggatcgg agctcagctc    120
agcgttcttg aagatctggc cttattccca gagcacagcc agttgagaac atgaaattgt    180
accacagctg gctcctggtt ggctcccgta ctgaggtgac acaagtgaat acaaccaact    240
gtggccgtct ccagagctgc tcagagtgca tcctggccca ggacccagtc tgtgcctgga    300
gcttccggct ggatgagtgt gtggcccatg ccggggagca ccgagggttg gtccaagaca    360
tagagtcagc agatgtctcc tctttgtgtc ctaaagagcc tggagaacgt ccagtagtgt    420
ttgaagttcc cgtggctaca gctgcgcatg tggtcttgcc atgttctcca agctcagcak    480
gggcakcctg tgtgtggcac cagcccagtg gagtgamtgc aytcamcccc cggcgggatg    540
gactggargt ggtggtgamc ccaggggcca tgggcgctta tgcctgtgaa tgtcaggagg    600
gtggggcagc ccatgtggta gcagcttaca gcttggtatg gggcagccag cgagatgctc    660
cgagccgggc g                                                         671

<210> 354
<211> 577
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (408)
<223> n equals a,t,g, or c

<400> 354
ggcagaggcg gcgtccgggg ctggcgttmc cctggaggct gagggtctca cggatggccc     60
cgctgccagg agcagaactg gttcggaggc cactgcagct ctaccgatac ttgctgcgct    120
gttgccagca gctgccgacc aagggcatcc agcagcatta caagcatgct gtcaggcaga    180
gttttcgggt tcattcagat gaagacaacc ctgagagaat ccagcagatt attaaaagag    240
ccattgaaga tgctgactgg atcatgaaca aatataaaaa acaaactgag agctccgagg    300
gtgagccttc ctggcctctg gaagttgaga ggcccctctt ctggagctca gcagcagcag    360
ctggtttgga agatccattg gccttgttgg ctgaaacacg agaatcangg ggagaagctg    420
accttgctcc agaggctcct cttgccgcgg ccatgttgct aagcatcctt tatgtttgca    480
cttccagcca ctttaccgat gtgaaatttg gggagaattg taagttattt ttttgcttct    540
ttttgtgtgt tttttattgg gtgtgttttt tgttcct                             577

<210> 355
<211> 451
<212> DNA
<213> Homo sapiens

<400> 355
ggcacgaggg cgctggaacc catggacacg gcgtatcccc gcgaggacac ccgggccccc     60
acgcccagca aggccggtgc ccacacagcc ctcacactgg gggccccgca ccccccgcct    120
cgagaccact tgatctggtc ggtgttcagc accctctacc tgaatctgtg ttgcctcggc    180
ttcctggcgc tggcctactc catcaaggcc cgagatcaga aggtggttgg tgacctggaa    240
gcggcccggc gttttggctc caaagccaag tgctacaaca tcctggccgc gatgtggacg    300
ctggtgccgc cactgctgct cctggggctg gtggtkactg gtgccctgca ctgtgcccgg    360
ctgccaagga ctctgccgcc ttcttcagca ccaagtttga tgacgcggac tatgactgac    420
aggctgggtc ctgatctggg gcactagcca g                                   451

<210> 356
<211> 873
<212> DNA
<213> Homo sapiens

<400> 356
aaaacattca cccagaaaac caggagctag taagggtact tcgagaacag cttcaaacag     60
aacaggatgc acctgctgcc actcgacagc agttctacac tgacatgtac tgtcccatct    120
gcctgcacca agcctccttc ccggtggaga ccaactgtgg acatcttttt tgtggtaacc    180
ttactcctaa cagtatttgg tgaagatgat cagtctcagg atgttctgag attgcatcag    240
gatattaatg attataaccg gagattctca gggcaaccca gatctattat ggagagaatt    300
atggatctac ccactttact gaggcatgca ttcagggaaa tgttttcagt cgggggcctt    360
ttctggatgt ttcgcatcag gataatactt tgtttaatgg gagctttttt ctatcttata    420
tcacctctag attttgtacc tgaagccttg tttggaattc taggctttct agatgatttc    480
tttgtcatct ttttattgct tatctacatc tctattatgt atcgagaagt gataacccaa    540
aggctaacta gatgaaaaag aaaacaaaac tgagtttact aggatatctg agctaatgta    600
gaacatcaaa cagaaggacc catggcagta taaagcaatg aagcaatgga gtattatctc    660
acaaatataa aaccactata agacaaacat ttgattatca tttgacaaat acctaggtat    720
aactggaatt ttcatgtttg aagttctaat attaagttta gaattataat gatctacagt    780
tgtatcttga ttctatgttg tctggaaaaa atatggaatt atataaaaag ggatgctttw    840
atatattttc cttttcccca gratactaga tta                                 873

<210> 357
<211> 1286
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (38)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<400> 357
cncngatttc aaaaggtcca cccacgcgtc cggggggncn gggctgtgtc cgcagtgtct     60
acaccccctc ctcacacgca cttcacctgg gtcgggattc tcaggtcatg aacggtccca    120
gccacctccg ggcagggcgg gtgaggacgg ggacggggcg tgtccaactg gctgtgggct    180
cttgaaaccc gagcatggca cagcacgggg cgatgggcgc gtttcgggcc ctgtgcggcc    240
tggcgctgct gtgcgcgctc agcctgggtc agcgccccac cgggggtccc gggtgcggcc    300
ctgggcgcct cctgcttggg acgggaacgg acgcgcgctg ctgccgggtt cacacgacgc    360
gctgctgccg cgattacccg gcccagctgc tggggggctg gcctgtctcc tgcccaggcg    420
aggagtgctg ttccgagtgg gactgcatgt gtgtccagcc tgaattccac tgcggagacc    480
cttgctgcac gacctgccgg caccaccctt gtcccccagg ccagggggta cagtcccagg    540
ggaaattcag ttttggcttc cagtgtatcg actgtgcctc ggggaccttc tccgggggcc    600
acgaaggcca ctgcaaacct tggacagact gcacccagtt cgggtttctc actgtgttcc    660
ctgggaacaa gacccacaac gctgtgtgcg tcccagggtc cccgccggca gagccgcttg    720
ggtggctgac cgtcgtcctc ctggccgtgg ccgcctgcgt cctcctcctg acctcggccc    780
agcttggact gcacatctgg cagctgagga agacccagct gctgctggag gtgccgccgt    840
cgaccgaaga cgccagaagc tgccagttcc ccgaggaaga gcggggcgag cgatcggcag    900
aggagaaggg gcggctggga gacctgtggg tgtgagcctg gccgtcctcc ggggccaccg    960
accgcagcca gcccctcccc aggagctccc caggccgcag gggctctgcg ttctgctctg   1020
ggccgggccc tgctcccctg gcagcagaag tgggtgcagg aaggtggcag tgaccagcgc   1080
cctggaccat gcagttcggc ggccgcggct gggccctgca ggagggagag agagacacag   1140
tcatggcccc cttcctccct tgctggccct gatggggtgg ggtcttagga cgggaggctg   1200
tgtccgtggg tgtgcagtgc ccagcacggg acccggctgc aggggacctt caataaacac   1260
ttgtccagta aaaaaaaaaa aaaaaa                                        1286

<210> 358
<211> 797
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (447)
<223> n equals a,t,g, or c

<400> 358
tccggaattc ccgggtcgac ccacgcgtcc ggcaagcttc ggtagtcctc tccgctgctg     60
tcgccaggag tcacttcacg agaagccagg tcacaaccgt cggcccttgt ctggaaaagt    120
aaaagtggat cctgccacgt tcggagctcc ctggcgcctc gcccggctgg agctagagaa    180
ctcgtcctgt ggcggccccc ggcgtggggc gggacagcgg ccccctggag ggggcagtcc    240
cgggagaacc tgcggcggcc ggagcggtaa aaataagtga ctaaagaagc agacctggga    300
atcacctaac atgtcgagga ggagatttga ttgccgaagt atttcargcc tactaactac    360
aactcctcaa attccaataa aaatggaaaa ctttaataat ttctatatac ttacatctaa    420
agagctaggg agaggaaaat ttgctgnggt tagacaatgk atatcaaaat ctactggcca    480
agaatatgct gcaaaatttc taaaaaagag aagaagagga caggattgtc grgcagaaat    540
tttacacgag attgctgtgc ttgaattggc aaagtcttgt ccccgtgtta ttaatcttca    600
tgaggtctat gaaaatacaa gtgaaatcat tttgatattg gaatatgctg caggtggaga    660
aattttcagc ctgtgtttac ctgagttggc tgaaatggtt tctgaaaatg atgttatcag    720
actcattaaa caaatacttg aaggagttta ttatctacat ccagaataac attgtacacc    780
ttgatttaaa gccacca                                                   797

<210> 359
<211> 2794
<212> DNA
<213> Homo sapiens

<400> 359
gtttaggtta caggcatata ctagtgtctc aaaggcttca cttggccttg cagatcacag     60
agaacttgga aagatgatga atacaataat ttttcataca aaaatggtag attccttggt    120
ggaaatgttg gtggaaacat cagatctctc catattttgt ttttatagtc gtgcttttga    180
gaagatgttt caacagtgtt tggagttacc ctctcaatca agatactcaa ttgcatttcc    240
actactttgc actcatttta tgagttgcac gcatgaacta tgtccagaag agcgacatca    300
tattggagat cgcagtcttt ccttatgtaa tatgttccta gatgaaatgg ccaaacaagc    360
tcgaaatctc atcactgata twtgcamaga acagtgtacc cttagtgacc agttgctacc    420
caagcattgt gccaaaacta tcagtcaagc agtgaataag aaatcaaaaa agcagactgg    480
taagaaaggg gaacctgaaa gggagaaacc aggtgttgag agcatgagga aaaacaggct    540
ggttgtgacc aaccttgata aattgcacac tgcactttct gagttatgct tctctataaa    600
ttatgtacca aacatggtgg tatgggaaca tacctttacc ccacgagaat atttgacttc    660
tcatctggaa atacgcttta ccaagtcaat tgttgggatg actatgtata atcaagccac    720
acaggaaatt gcaaaacctt cagaacttct aacaagtgta agagcataca tgaccgtact    780
ccagtcaata gaaaactatg tgcagattga tattacaaga gtatttaata atgtgcttct    840
tcaacaaaca caacatttag acagtcatgg agagccaacc attacaagtc tatacacaaa    900
ttggtatttg gaaactttgt tacgacaagt cagcaatggc catatagcat attttcctgc    960
aatgaaagcg tttgtgaact tacctacaga aaatgaatta acattcaatg cagaggaata   1020
ttctgacata tcagaaatga ggtcattatc agaactacta ggcccatatg gtatgaagtt   1080
tctaagtgaa agccttatgt ggcatatttc atcacaagtt gctgaactta agaaacttgt   1140
ggtggagaat gttgatgtgt taacacaaat gaggaccagc tttgacaaac cagaccagat   1200
ggctgcactg tttaaaagat tatcatctgt tgacagtgtc ttgaagagga tgacaataat   1260
tggtgtaatt ttatccttcc gatcattggc acaagaagca cttagagatg tsttatccta   1320
ccacattcct tttcttgtaa gttcaattga agattttaag gatcacattc caagggaaac   1380
tgatatgaag gttgcaatga atgtgtatga gttatcatca gctgccggat taccttgtga   1440
gattgatcct gcattggtcg tagctctttc ttcacaaaaa tcggaaaaca ttagtccaga   1500
agaagagtat aaaattgcct gccttctcat ggtgtttgtg gcagtttctt tgccaacact   1560
ggccagtaat gtgatgtctc agtacagccc tgctatagaa gggcattgca acaacataca   1620
ttgcttggcc aaagccatca accagattgc tgcagctttg tttacaattc acaaaggaag   1680
cattgaagac cgtcttaaag aatttctggc gcttgcatcc tccagtctac tgaaaattgg   1740
ccaggagaca gataaaacta caacaagaaa tagagaatct gtttatttac tgctagatat   1800
gattgtacaa gaatctccat tccttacaat ggatcttttg gaatcttgtt ttccttatgt   1860
cttgctgaga aatgcatacc atgctgtcta caaacaaagt gttacatctt ctgcataaaa   1920
ttacctactt aatcaagata agcacgcatt tttgttgcct tggttttacc tgtagactgt   1980
ggaactattt taccttaaga cctgaaaaag ttttgtggat tataaatttc tttcatacgg   2040
ttgtattttc tgatcattgg tttcttaata tggttgtact acagtatact tggttgattt   2100
aggttgcaca ttcactgaat tcactgagat tattcctata attttaaagt atcatttatt   2160
tgaaaaacat acattatcaa catgtttttg atatttgata atgaaaaaaa tctttgcttg   2220
tttatttctg aaaaagaact gtatttagtg attattttag atagtgatat tatagcattc   2280
atctgtgtgt aaattatttc atatagggaa gagttctgat ctgtacctat ggttcttatt   2340
gaaaacaaca ttggatgtgc atttctgtga tgttatgaat acatttctac tttattttga   2400
aacatttgcc aaactaaata ctgtaacact gtataacatt taaaaatgtt aaagaactgc   2460
ttagtattag aagcagatca tttcccaaaa ttctaagagc agcagcatat gttgttgctt   2520
gtataaagcc tagcgataat ttttagacta acttccatgg tgccctgttg gcattagcac   2580
taccattgta ccctgctgta taataaacaa tcttagacat ttatcaactg ttgatacaaa   2640
tgttagtccc taaccacttt ttatatatgt tttaaatttt tgaaattcaa gtgtaccttc   2700
cataacataa aataaacact agactgtatc acaaaaaaaa aaaaaaaaaa aaaaaaaaac   2760
tcgagggggg gcccgtaccc taatcgcctg tatt                               2794

<210> 360
<211> 1466
<212> DNA
<213> Homo sapiens

<400> 360
acctgcaggt accggtccgg aattcccggg tcgacccacg cgtccgagcc gtccgcgctc     60
cgaacggcgc ctcccgcccc accatgggca acagcgcgag ccgcaacgac ttcgagtggg    120
tctacaccga ccagccgcac acgcagcggc gcgcgcggcc ccctgccaag tacccggcca    180
tcaaggccct gatgcggcca gacccgcgcc tcaagtgggc ggtgctggtg ctggtgctgg    240
tgcagatgct ggcctgctgg ctggtgcgcg ggctggcctg gcgctggctg ctgttctggg    300
cctacgcctt tggtggctgc gtgaaccact cgctgacgct ggccatccac gacatctcgc    360
acaacgcggc cttcggcacg ggccgtgcgg cacgcaaccg ctggctggcc gtgttcgcca    420
acctgcccgt gggtgtgccc tacgccgcct ccttcaagaa gtaccacgtg gaccaccacc    480
gctacctggg cggcgacggg ctggacgtgg acgtgcccac gcgtctggag ggctggttct    540
tctgcacgcc cgcccgcaag ctgctctggc tggtgctgca gcccttcttc tactcactac    600
ggccgctctg cgtccacccc aaggccgtga cccgcatgga ggtgctcaac acgctggtgc    660
agctggcggc cgacctggcc atctttgccc tttgggggct caagcccgtg gtctacctgc    720
tggccagctc cttcctgggc ctgggcctgc accccatctc gggccacttc gtggccgagc    780
actacatgtt cctcaagggc cacgagacct actcctacta tgggcctctc aactggatca    840
ccttcaatgt gggctaccac gtggagcacc acgacttccc cagcatcccg ggctacaacc    900
tgccgctggt gcggaagatc gcgcccgagt actacgacca cctgccgcag caccactcct    960
gggtgaaggt gctctgggat tttgtgtttg aggactccct ggggccctat gccagggtga   1020
agcgggtgta caggctggca aaagatggtc tgtgagcccg ggctgcctcc tggtggtggc   1080
cattgtcccc catcggcccc tcagccttgc accccagcac tgagaagcta catttccttc   1140
ctgtgctctg gactgctgcc cttgtccccg aggagtgtcc cgcgcagcca cacctggcaa   1200
cagcagtgtg ggctgcaggg ctccgtctgc acgtggactt gccctggacc ttgagtgtgg   1260
ccctcccttt ctgggcctcc ccaggtgagg cctggccctg ccccaccatg acctgggtgc   1320
tctgagccca cggttcccac ggagctgact tctccggggt gcctgtgccc tacattaaac   1380
ccggcgtttg tttcacaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1440
aaaaaaaaaa aaaaaaaaaa aaaaaa                                        1466

<210> 361
<211> 937
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (918)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (926)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (937)
<223> n equals a,t,g, or c

<400> 361
ggacccacgc gtccgcccac gcgtccggtg cttgctatga catctggtca aatgtggaac     60
catataagag gaccaccata tgcccataag aatccccaca cgggacatgt gaattatatc    120
catggaagca gtcaagccca gtttgtagct gaaacacaca ttgttcttct gtttaatggt    180
ggagttacct taggaatggt gcttttatgt gaagctgcta cctctgacat ggatattgga    240
aagcgaaaga taatgtgtgt ggctggtatt ggacttgttg tattattctt cagttggatg    300
ctctctattt ttagatctaa atatcatggc tacccataca gctttctgat gagttaaaaa    360
ggtcccagag atatatagac actggagtac tggaaattga aaaacgaaaa tcgtgtgtgt    420
ttgaaaagaa gaatgcaact tgtatatttt gtattacctc tttttttcaa gtgatttaaa    480
tagttaatca tttaaccaaa gaagatgtgt agtgccttaa caagcaatcc tctgtcaaaa    540
tctgaggtat ttgaaaataa ttatcctctt aaccttctct tcccagtgaa ctttatggaa    600
catttaattt aagtacaatt aaagtataat tataaaaatt gtaaaactac tactttgktt    660
tagttagaac aaagctcaaa actactttag ttaacttggt catctgawtt tatattgcct    720
tatccaaaga tggggaaagt aagtcctgac caggtgttcc cacatatgcc tgttacagat    780
aactacatta ggaattcatc cttagcttct tcatctttgt gtggaatgtt gttatacttt    840
acgcatcttt ccttttgagt agagaaatag tgtgtcaggt ggtcttcctg aaaatggaac    900
acatcttcca aaaaaagntc taaccnccaa aaaaagn                             937

<210> 362
<211> 456
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (431)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (438)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (450)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (456)
<223> n equals a,t,g, or c

<400> 362
gaattcggca cgaggcagtt tatagcaaag tctgctgtgc tgcagctggc actagctggc     60
gcctttgggc agtttctgct aaaccttgag caattgcttt cactcttcca cctcccatgt    120
tgtttcattc attcaatctt agatggaatt ggttagagag gagaaataga acactattta    180
aaacaagaga aatggtatat ccccctctgg cagagaacac aggtaagaca ttacctcttg    240
tacttgatgg gagaacatct ttttttttct ttctttcttt tttgtttgtt tgtttgtttg    300
ggacaaagtc tcactctgtt gcccaggctg gaggttgcag tgagctgaga tctcaccact    360
gcaactccag cctgagcaac aaagcaagac tccatctctt aaaaaaaaaa aaaaaaaact    420
cgaagggggg nccggtancc caattggccn aaaagn                              456

<210> 363
<211> 461
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (361)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (413)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (421)
<223> n equals a,t,g, or c

<400> 363
gaaaggaccg gccaaacaag agggttaaga tttctgtttc tcttgctggg cttttggcag     60
tagggggctg tgttggtggg ccctacgaag atgctcagtg ctcgagatcg ccgggaccgg    120
caccctgagg agggggtagt tgcagagctc cagggcttcg cggtggacaa ggccttcctc    180
acctcccaca agggcatcct gctggaaacc gagctggccc tgaccctcat catcttcatc    240
tgcttcacgg cctccatctc tgcctacatg gccgcggcgc tactggagtt cttcatcaca    300
cttgccttcc tcttcctcta tgccacccag tactaccagc gcttcgaccg aattaactgg    360
ncctgtctgg acttcctgcg ctgtgtcagt gccatcatca tcttcctggt ggnctccttt    420
ncaagctgtg acctcccggg atggagctgc cattgctgct a                        461

<210> 364
<211> 776
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<400> 364
cncnnctgaa atcncntcac ttttgggaac aaaagccgga gctccaccgc ggtggcggcc     60
gctctagaac tagtggatcc cccgggctgc aggaattcgg cacgaggaaa attttgagtt    120
acagtatcat tcgaagagaa tttatttctg cctttcatgt tatagcccct aagggatcca    180
ggacccgaaa ggccagyttc tccctcattt tgaaatcagt tttctccacc tgcaccactg    240
catagcacag atacagaaac catcctattt caggatttga atgcaaaact taccttctta    300
ctctaaagat gaatgatcag ggagagattt attcaaccct gagatttttg cagtctcctt    360
cagagtcaca gaatagatta aggcctgatg atactcaaag gcctgggaaa actgatgaca    420
aagaattttc agtgccctgg cacctcattg cagtgactct tgggatcctc tgtttacttc    480
ttctgatgat agtcacagtg ttggtgacaa atatctttca gtgtattcaa gaaaaacatc    540
aacggcagga aattctaaga aactgtagtg aaaagtacat catgcaaaat gacaactact    600
taaaagagca gattttgaca aataagactt taaaatatga cgttctcaaa aatagctttc    660
agcagaaaaa ggaactggat tcacgcctta tacaaaagaa cagatgtcat agagaaawtg    720
agatcrtttt taaagttttg caaaatacag gcaattctct gaagaccacg ggtcct        776

<210> 365
<211> 653
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (559)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (594)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (639)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (643)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (644)
<223> n equals a,t,g, or c

<400> 365
gccccnttga gcggatccca atttcacaca ggaaaacagc tatgaccatg attacgccaa     60
gctcgaaatt aaccctcact aaagggaaca aaagctggag ctccaccgcg gtggcggccg    120
ctctagaact agtggatccc ccgggctgca ggaattccct taaacaatac acattcatta    180
tctttcattt ctggaggtcg gaagtttgaa atgggtcttg gtgggctaaa atctagacat    240
tggtagggct gtgttcattt atggaggttc tagacaaaaa tctatttttc tttttttttt    300
tgagatggag tcttggtctg tcgcccaggt tagagtgcag tggcaccatc tcggctcact    360
gcaacctcca cctcctgggt tcaagtgatt ctcctgcctc agcctcccgg gtagctggga    420
ttgcaggtgc tcgccactgc gcctggctaa tttttttttt tttttgtatt tttggtagag    480
atggggtgtc accgtccttg gccaggctgg tctcggaact cctgaccttg cgatctaccc    540
cacctcggcc ttccaaagng cttgggatta aaggcttgag ccaccgtgcc cagntggcaa    600
taatctattt cttgcctttt ccatttctaa gaggctacnt aannggttct tgg           653

<210> 366
<211> 1531
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1531)
<223> n equals a,t,g, or c

<400> 366
gctcgtgcck caagaatgac acagctgctg tgcakckcac ttcgtctctg gcaacaacgt     60
cctggcccat cggtccctgc ccctttctga aggagggccc ccactaagga tcgcccagag    120
gatgcggctg gaggcaacgc agctggaagg ggttgcccga aggatgacgg tggagacaga    180
ttactgtctg ctgctggctc tgccctgtgg ccgtgaccaa gaggatgttg tgagccagac    240
cgagtccctc aaggctgcct tcatcactta cctgcaggcc aagcaggcgg cagggatcat    300
caacgttccc aaccctggct ccaatcagcc tgcctacgtg ctgcagatct tcccgccctg    360
tgagttctct gagagtcacc tgtcccgcct ggcccctgac ctccttgcca gcatctccaa    420
catctctccc cacctcatga ttgtcattgc ctccgtgtga gccactgagt ggttatcacc    480
tcagtgaatc ttcccagggc tctgcagtaa aaacaaagga caacccagcc aagcagagga    540
agaagctgcc gaaggggaca gactccactg ccagacggcc agccgtttgc tgtcctgccg    600
cccggctcag tcggccagac ttcctctagg agtggtgctg ctaccttgta tgtttacata    660
atgctttagc ccaaggacac atcaccaacc catggactcg cagacaccgg ggctgggttt    720
ctctttcctc tttttggaga aaaggaacag ggcagtggaa tgaaaatttt ttgtttgttt    780
gtttttaaga aacaagaaaa cagaactgcc tttgcactaa attagtgact tggacttttg    840
cccagtgaag acaggctgtg acactctgga tgtcttggtg tgtgtagaca cacattgcag    900
actcttaacg caggaaggac ttcaaacttc tgctgagacc ttggggtcaa ggaacatttc    960
attggttttt tttgtccacc cccatctccc ttgctcattt ggatgcgtca ccttaattct   1020
cctgctgcca ccgtctttga ttcaccggga tgtacagttt acagttgaag agcaaacaga   1080
aaggttttct cttggtggga tatgcagaac ttgggatgtg tgtatatata aatatataat   1140
atatataaat atatataata ctgacttaaa aaatcaaatc ccccgacata cgtttttttt   1200
aatctgtgcc aaaaatgtgt tttcagagga aatcttattt tcatattcag actttgtatt   1260
gcccactcat ttgtataagt gcgcttcggt acagcacggg tcctstcccg cgatgtggaa   1320
gtgtcacacg gcacctgtac aaaaagactg gctaacccct cttcctatta ccttgatctc   1380
ttcccccaac ttcctaacac ttattaattt atgaaactgt ttttctcagc gcagttttgt   1440
tttgtgtgtc cattggatta caaactttat taaaaaatat aaaacacaaa aaaaaaaaaa   1500
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa n                                  1531

<210> 367
<211> 3803
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (26)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3789)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3796)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3797)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3800)
<223> n equals a,t,g, or c

<400> 367
gcaactctat anatcatata ggaaanggta nctgcagtac ggtcggaatt cccgggtcga     60
gtaacacagt tagaaggaaa ttcatgtgaa attttatggg agacggtacc atcaatgaaa    120
ggtgaccctg ttaactacat tctgcaggta ttggttggaa gagaatctga gtacaaacag    180
gtgtacaagg gagaagaagc cacattccaa atctcaggcc tccagaccaa cacagactac    240
aggttccgcg tatgtgcgtg tcgtcgctgt ttagacacct ctcaggagct aagcggagcc    300
ttcagcccct ctgcggcttt tgtattacaa cgaagtgagg tcatgcttac aggggacatg    360
gggagcttag atgatcccaa aatgaagagc atgatgccta ctgatgaaca gtttgcagcc    420
atcattgtgc ttggctttgc aactttgtcc attttatttg cctttatatt acagtacttc    480
ttaatgaagt aaacccaaca aaactagagg tatgaattaa tgctacacat tttaatacac    540
acatttattc agatactccc ctttttaaag cccttttgtt ttttgattta tatactctgt    600
tttacagatt tagctagaaa aaaaatgtca gtgttttggt gcaccttttt gaaatgcaaa    660
actaggaaaa ggttaaactg gatttttttt ttwaaaaaaa gaaaaaaaaa gaagaaaagt    720
ataccagata ccaaaagcta gctttcttat gttttccttt aaattttcag atttaccttc    780
attctgtttt cactgatgtc ttttgcaagc ctttgatttt ttttttttgt tacagtttag    840
taatttatat tcaccagtca cttcttatgt cttgaacatc tgtatctgta aacatgaatc    900
accgtgtgtg tacttacagg gctaggattt cagtgttgtc agagtattac cacacagcaa    960
cagcaacata cagaagatat gttcactcag ataagactgc cctaaacaac cattttgtca   1020
ctcagttatt taactgtgtt tagctcattt aaatcaaaat gtgtacttta atctaaaatg   1080
ttttaataat ctgtatttct tataatttta acactatgag ctgcctatat aagaaatcaa   1140
gtaaccagaa tgcacctata aattatggga gcattgtaga ttttaccaca tcaattcata   1200
gcagtaactt taagagggca ttgtgcaata gttagttgtt ttcttgttca gctattttaa   1260
aggctgcttt aacttgtttg tttgtctttg tatataacta cttctaatct aatcactaga   1320
gttattatat tctgttatgt ttgaccagaa ttatatgaca agaactggtg acagtttagt   1380
gcctctgccc attgtccatg atttacacta attgtgagca gtcttcttat gtgtcagctc   1440
attatttttg aaacatttgc ctttaggctg ttctttgagg tatcaatgaa gtgattgaat   1500
ttcaatacct taattcagtg cacataatac taatgtaaca gcagatgaaa attgataaaa   1560
cccaaaagag agtcatctaa atttgtagtt cctatttctg tgggtttgcc tggccatggt   1620
tggagaggga atggtgtttg atggtaaaca cagggtgttt ggggatcaag gagcctagat   1680
tctctccctg gatctgtcac taacttgctg cgtgacctga acacgtcact ttacctctct   1740
gtgcctcagt tttcccatgc atgaaaaata aaataaaata aaacggggat tctaatgttt   1800
gtaagtgctt tgagatcttt gaccaacagg tgctattgga gtgcaaagtg ttactcttac   1860
gtgtttattt tgagtcatga gataatcaat tttaacccaa agtcattgga ttatttatat   1920
gaagtccata atgttcgagt acctcaggga catttaagag ttggaggtgc aaatatattc   1980
caaaagggtg caacagacac agtgtatccc cctgcttctg tttttgtata tttttgctac   2040
ttggtttttc ttgatcatag ctattttgtg cytgatcytt attgkcyaag atgcagtatc   2100
ctgtactagc ytataatatt cccataccaa agtcatgggg aaacaaacat tattttgttt   2160
ttggtttatt tatacctata ttctgcatac agtactttaa atgccaatta cagtgcaatc   2220
tttatttatt gtaaaatttt ttaagtgtac ttatgtacta attttccctt gtagcatgtt   2280
atatttttgt gttttatact tttgtaattt taggtcagtc ttgttccttg gcaacatctg   2340
tagtattatt aatcttctga cattttctta tgtttttaaa aagataagag catctagtgc   2400
attaaatgcc aaaaaaaaaa tacattatca gtgattgaaa cgtttacatg tacccaaaaa   2460
ccataatcat ctcttggaag aaaatgctga gatcaatgaa ttattctgtg tgcctatatt   2520
gacgtagtga gtactagaga gttctgtatt ttattattga ctataataat tagtttaatt   2580
agctttgcaa actgatggca tcaaggtaaa tatatttttg ccaaagttct ggccttccaa   2640
aactcacccc cttatttaaa tgtgtgctat gacccactat gacacagcat ctgcattttc   2700
taaaaaattc catgcaggtg ttttggggag aggtattttt taagcaatga aaattcaact   2760
gagtacaaag ccccctcttg gggggttggg gaagtctctt ttttgaaaca cttcagaact   2820
gctgctataa agaaattctc taattggttg aatttttttt taagtaaata gtactttagg   2880
ccaaaattta tatgaatatt tgatcttctt gagattttca tactatcatt taaccaccag   2940
gaagctgaag tgtgtgaagt acaaagctga cagcacttta ttttattgct ctccattatt   3000
tggtattcat tatattcctt cagtcagaaa attattactc tctatggcac tgttttttat   3060
cacaaatatg tatatgtgat attgatatat aactatatat attgccatca cacacgaaca   3120
ataaaataaa gtgttctatt aacctgatct ctttgccctt ttgctatgtg aggagtgaat   3180
gagtggcctt ctgatgctct gactcttctc tgtatgtcaa actcatccct ggcacaagaa   3240
attccagtca tgtgaagcaa actgcccttt gtcctcaaag aaattgttga aaaagaaaac   3300
tttttaaaga gattttttgc atattctctg ccttgttctt atcaacttga aatgttggca   3360
ttttctaacc ttgttttgtt ggctacaata attcagtatt catgtcaaaa ttgagaagtg   3420
ccctaattga atgtgtttga atgttatcct tgcacaattc tttaaattga aagataaaat   3480
gttttacctc actgttggac atacattcca agcttttcaa ctctaggaga aaaagaaaat   3540
catgttttcc tgtattgtaa attttagact atttcatata cattgtatta aaactgccat   3600
atcaatttta atgtatagat tttgcaaata ttatgctata tgtaatacct aactgtatct   3660
gtagtgtata tgtaatatat ttatgcccaa taaatgtttt aattctttct gacttaaaaa   3720
aaaaaaaaaa aaaaaaaaaa aaagggcggc cgctctagag gatccaagct yacgtactgy   3780
gtgcatgcnc tgtcanntgn cat                                           3803

<210> 368
<211> 709
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (708)
<223> n equals a,t,g, or c

<400> 368
acccacgcgt ccgagcaaga tggcgccgcg ggcatttctt ccactgcccg tctgagggaa     60
cgctaagtag tgtgtccggc gccgtgttcc agctccgcgt tgttccgcga gaaagcgaga    120
ggccgagccc gggctggtgc gatggccgcg gtggtggcca agcgggaagg gccgccgttc    180
atcagcgagg cggccgtgcg gggcaacgcc gccgtcctgg attattgccg gacctcggtg    240
tcagcgctgt cgggggccac ggccggcatc ctcggcctca ccggcctcta cggcttcatc    300
ttctacctgc tcgcctccgt cctgctctcc ctgctcctca ttctcaaggc gggaaggagg    360
tggaacaaat atttcaaatc acggagacct ctctttacag gaggcctcat cgggggcctc    420
ttcacctacg tcctgttctg gacgttcctc tacggcatgg tgcacgtcta ctgaaatggg    480
ggcccggggg acttttttaa aaaaccagat cgggaggact gtggccagca attaacacca    540
tgtagacttc cttagttctt aagtggttga attcgctgct tgttctgtaa cgttataaat    600
aatttatatc tgaagacgga gagcctgtaa tattcttcag attaaatgaa gcgtgagaca    660
maaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaccccgggg ggggcccng                709

<210> 369
<211> 1136
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1124)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1131)
<223> n equals a,t,g, or c

<400> 369
ccgactcctc cgacgccgat ccggacagcg gcacagagga gggagatttg ggacttccca     60
ggacagattg acttttttga ccctacattt gactatgaga tgatcttccg gggaacagga    120
gcactgatat ttgtcattga ctcacaggat gattacatgg aagccctggc caggctccac    180
ctcacggtga ccagggccta caaagtgaat actgacatca acttcgaggt gtttattcat    240
aaagtggatg gtctgtcaga tgaccacaaa attgaaaccc aaagagatat tcaccagagg    300
gcaaacgatg accttgcaga tgctggatta gaaaaaattc acctcagctt ttatctgaca    360
agcatatatg atcattcaat atttgaagct tttagcaaag ttgttcagaa actgattcca    420
caactcccaa ctctggagaa tttgctgaac atctttatct caaattctgg aattgaaaag    480
gcatttctat ttgatgtggt cagtaaaatt tatattgcaa ctgatagtac tccggtggat    540
atgcaaacct atgagctctg ctgtgatatg atagatgtgg ttattgacat ctcttgtatt    600
tatggtctca aagaagatgg agcaggaacc ccctatgaca aggaatccac agccatcata    660
aagcttaata atacaaccgt gctttattta aaagaggtga caaagttcct ggctctcgtt    720
tgctttgtca gagaggaaag ctttgaaaga aaagggctaa ttgactataa ttttcattgc    780
ttccggaagg ccattcatga agtttttgag gtgagaatga aagtagtaaa atctcgaaag    840
gttcagaatc ggctgcagaa gaaaaagaga gccaccccta atgggacccc tagagtgctg    900
ctgtaggtga ggtttcagga atgtcttttg aaatcagacc ttatccatga ggctgctgcg    960
ccatgttgca ctaaaggaag aggaagaagg agattgggac acataccatt gatttgttgt   1020
taaaaaaaaa aaattcctgc aaccctcttg atcttctctt ttataaataa agtaagcact   1080
ttgaagcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaangggggg nccccc       1136

<210> 370
<211> 665
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (616)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (656)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (665)
<223> n equals a,t,g, or c

<400> 370
aaagagtgtc cctagttgta acagaaactg tcgatgcagg tttatttgga gaaggaattg     60
tggagagttt gattcatgca tgggagcatt tacttttaca gccaaagacc aaaggtgaaa    120
gtgctaattg tgaaaagtat gggaaagtta taccagcaag tgctgttata tttgggatgg    180
cagtagaatg tgcagagata agaagacatc atagagtggg tattaaggac attgctggta    240
tccatttgcc aacaaatgtg aaatttcaga gtccggctta ttcttctgta gatactgaag    300
aaacaattga accttataca actgaaaaga tgagtcgagt tcctggmggr tatttggctt    360
tgacagagtg ctttgaaatt atgasagtag atttcaacaa ycttcaggaa ttaaaaagtc    420
ttgcaactaa raarcctggt aaaattggta ttcctgttat taaagaaggc atattagatg    480
ctgttgtggt ttggtttgta ctccagcttg atgatgaaca tagtttatcc acaagtccta    540
atgaggaaac atgttgggaa caagctgtct accctgtaca tgaccttgca gactaccgga    600
taaaacgtgg ggaccngtga tgatggaatg tcttgtccaa gattgttact taagantcca    660
gaatn                                                                665

<210> 371
<211> 984
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> n equals a,t,g, or c

<400> 371
caagatattt acttccgctc caaacaaaga tgggccagct aacgagcncg ggggaaacat     60
ccgcccggaa ggccacttga aggcacttcc gccctctctt aacatggagc cggcggaagg    120
ggtggtgtag ggccgggcga taatggcggc gtcgaggctg gagctaaacc tggtgcggct    180
gctatmccgc tgcgaggcga tggcagcgga gaaacgggac ccggacgagt ggcgcctgga    240
gaagtacgtg ggagccctag aggacatgtt gcaggccctg aaggtccacg cgagcaaacc    300
ggcctctgag gtgatcaatg aatattcctg gaaggtggat tttctgaagg ggatgctgca    360
agccgagaag ctgacctcct cctcagagaa agcactggcc aaccagttcc tggcccctgg    420
ccgtgtgcca accacagcca gagagcgagt gcccgccaca aagacggtgc atctgcagtc    480
acgggcgcgg tacaccagcg agatgcggag tgagctacta ggcacggact ctgcagagcc    540
tgaratggac gtaaggaaga gaactggagt ggcagggtcc cagccagtga gtgagaagca    600
gtcggcagct gagctagacc tcgtcctgca gcgacatcag aacctccagg aaaagctggc    660
ggaagagatg ctaggactgg cccggagcct caagaccaat accctggccg cccagagtgt    720
catcaagaag gacaaccaga ccctgtcaca ctcactgaaa atggcggacc agaacctgga    780
gaaactgaag acggagtcag agcgtctgga gcagcacacg cagaagtcag tcaactggct    840
gctctgggcc atgctcatta tcgtctgctt catcttcatt agcatgatcc tcttcattcg    900
aatcatgcct aaactcaaat aaagaccccc gcccaaaaaa aaaaaaaaaa aaaaaaaaaa    960
aaaaaaaaaa aaaaaaaaaa aaaa                                           984

<210> 372
<211> 2494
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2471)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2485)
<223> n equals a,t,g, or c

<400> 372
caaagaaaca ttggaaacaa tttctaatga agaacaaaca cctcttctta aaaagattaa     60
cccaaccgaa tctacttcca aagcagaaga aaatgaaaaa gttgattcaa aagtgaaagc    120
tttcaagaaa ccattgagtg tatttaaagg ccccttacta cacatcagcc cagcagaaga    180
actgtacttt ggaagtacag aatccggaga gaagaaaacc ttaatagtgt tgacaaatgt    240
aactaaaaat atagtggcat ttaaggtgag aacaacagct ccagaaaaat acagagtcaa    300
gccaagcaat agcagctgtg acccgggtgc atcagtggat atagttgtgt ctccccatgg    360
gggtttaaca gtctctgccc aagaccgttt tctgataatg gctgcagaaa tggaacagtc    420
atctggcaca ggcccagcag aattaactca gttttggaaa gaagttccca gaaacaaagt    480
gatggaacat aggttaagat gccatactgt tgaaagcagt aaaccaaaca ctcttacgtt    540
aaaagacaat gctttcaata tgtcagataa aaccagtgaa gatatatgtc tacaactcag    600
tcgtttacta gaaagcaata ggaagcttga agaccaagtt cagcgttgta tctggttcca    660
gcagctgctg ctttccttaa caatgctctt gcttgctttt gtcacctctt tcttctattw    720
attgtacagt taaagaagtg gtgccgggta ggaaccacgg ttccttcgtc cattagttgg    780
aaaagtaaca gacctaaaac tctaccaagc tactaaaamc attgcacatc tgtgcttcct    840
aaaaggaaat atgcagcacg tggaggggaa cacatacatg tcttgaaaat aaactgctag    900
aataaagaaa tgctggagaa attgattata agagactata gctatttagt aaagtaagta    960
aaggcatatc cattgtgtaa attaatagtt taaatataat ttattttttc cttttgatct   1020
gaatactttt aaagcttaag ttttatcgtg taaatacatt agctaaactg aaaagtataa   1080
gtaacatgct ttgttgcagc caaaaaatgt aatctgcttt tttatgacag aattattata   1140
gctgagctga cttactagct tttctatact atgtatatag aagaacatgt atattgagaa   1200
agaaaacata cttatataga ggaatttatg taaccatgac tttgtaattt tgagaattcc   1260
tcccagtgat ggtcagtatt cttttggaat gtaaaccgat ttaatgccaa accaccttaa   1320
cctttgtttc tcagtgttcc ttaacagcct gccttttatt aatctcaggc ttttttatga   1380
acactctcat ttcagtagaa tttggaaaac taagcgtggt tggaatttct ttgaattctg   1440
ttagtaatgc ccaaaagaaa agtctcaagc agtcccccta tccagtcatt tttatggagt   1500
ttcatgttgt ccactatagc tggacactga accttttgcc taatttatta taaaggcctg   1560
accctctatt gtcccatctt cacccccatt ccagagcaga ggagtctctg tggaccatga   1620
attgcactgt ctccctcctc atttctaaat gaaaggtatt agatataaat ttttttgaaa   1680
ggttagttgt ttgagatgct aagcaggata ataaatttag attttaaaat gttccctgta   1740
aaagtcagcc catgacaagg aaatttacaa aatactagag tatctagaag ggtgaaaaca   1800
aaaaaaaawa aaaaraaaca cagacgccca ggtgtcagct ctccgtttaa agaatgaaaa   1860
atgtaactca tgatgatctg tgaaaccttc aaactaggac caattgactt acttgatatt   1920
ctgcctttga tatggtagta cccacccggt attcctaaaa tcctaaaaag atacaccttg   1980
cagtagcaga ggcaatgaca tgagtttgtt ttctcattaa tatgaccagt ttgggtctat   2040
gttggttcac atgtacatct actttatatg aaagaaaaaa cagttgtctg cctgtaaaat   2100
gttgagtttc gattgagcca tgtttggaga ttttattact attctgaagg gtagtgttgt   2160
tggttttcat cttcaagaag ttgattccaa aactgagtta tgaagaatga tataacagtt   2220
ccttcaaaat tggcctagga aataaaacct taaaaggaca ctggtgtgct actttgtctt   2280
aatttgggct tttctgtttc agtttgccac ctccagctgt gaaatggact gcagtccacc   2340
ctaagtactg tgcacagtat ctccctgtgt gtgtgcacag tggcttcccc ttacatggta   2400
gatttttggc cttaatataa tctaatccca aagtagttgt gtatgttttc tgttccttgg   2460
caataaaatg naggaataat ttagnccaag attg                               2494

<210> 373
<211> 2438
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (879)
<223> n equals a,t,g, or c

<400> 373
ggtgcagttc caacagtaac agcgaaaatc atcgggtgat gcaagtactc aaacagatgc     60
cctgaaactg ncaccttcca accttcaagg cttttgaaga acaaagcttt attatgcaaa    120
cccatcacac agactaaagc cacctcttgc aaaccacata cccaaaacaa agaatgccag    180
acagaagaca ctccaagtca gcccagatta ttgkggkgcc agttccgtac cagkgttkgt    240
cccatacctc ttacctttat actcaatatg ctccagtccc atttggaatt ccagktccaa    300
tgcctgkccc tatgcttatt ccatcttcaa tggatagtga agataaagtc acagagagta    360
ttgaagacat taaagaaaag cttcccacac atccatttga agctgatctc cttgaratgg    420
cagaaatgat tgcagaagat gaagagaaga agactctatc tcagggagag tcccaaactt    480
ctgaacacga actctttcta gacaccaaga tatttgaaaa araccaagga agtacataca    540
gtggtgatct tgaatcagag gcagtatcta ctccacatag ctgggaggaa gagctgaatc    600
actatgcctt aaagtcaaat gctgtgcaag aggctgattc agaattgaag cagttctcaa    660
aaggggaaac tgaacggacc tggaagcaga ttttccatca gactcctttg acccacttaa    720
taaaggacgg gaatccaggc acgttcccga acagacgacg acacagagat ggcttccccc    780
aacccagacg aagaggacgg aagaagtcta tagtggctgt ggagcccagg agtcttattc    840
aaggagcctt tcaaggctgc tcagtgtccg ggatgacant gaaatacatg tatggggtaa    900
atgcttggaa gaactgggtt cagtggaaaa atgccaagga agagcagggg gatctaaaat    960
gtggaggggt tgaacaggcc tcatctagcc cacgttctga ccccttagga agtactcaag   1020
accatgcact ctctcaagaa tcctcagagc caggctgtag agtccgctct atcaagctga   1080
aggaagacat tctgtcctgc acttttgctg agttgagttt gggcttatgc cagtttatcc   1140
aagaggtgcg gagaccaaat ggtgaaaaat atgatccaga cagtatctta tacttgtgcc   1200
ttggaattca acagtacctg tttgaaaatg gtagaataga taacattttt actgagccct   1260
attccagatt tatgattgaa cttaccaaac tcttgaaaat atgggaacct acaatacttc   1320
ctaatggtta catgttctct cgcattgagg aagagcattt gtgggagtgc aaacagctgg   1380
gcgcttactc accaatcgcc ttttaaacac cctycttttc ttcaatacca aatacttyca   1440
actaaagaat gktactgagc acttgaagct ttcctttgcc catgtgatga gacggaccag   1500
gactctgaag tacagtacca agatgacata tctgaggttc ttcccacctt tacagaagca   1560
ggagtcagaa ccagataaac tgactgttgg caagaggaaa cgaaatgaag atgatgaggt   1620
tccagtgggg gtggagatgg cagagaatac tgacaatcca ctaagatgcc cagtccgact   1680
ttatgagttt tacctgtcaa aatgttctga aagtgtgaag caaaggaatg atgtgtttta   1740
ccttcaacct gagcgctcct gtgtcccgaa tagccccatg tggtactcca cattcccgat   1800
agaccctgga accctggaca ccatgttaac acgtattctc atggtgaggg aggtacatga   1860
agaacttgcc aaagccaaat ctgaagactc tgatgttgaa ttatcagatt aaaacggaag   1920
tgaggttctt attttcatac atattggtat gcaccaaact gtgaatgcat ccagctgttg   1980
gaaaatgatg tataagtcta agtcctcttg acttgaccat aagatcatgg aaaacagatg   2040
acttgtgaac cccacagtgt ggatgtgcaa atgaaaattg aaggaaagaa tatgaactga   2100
gaaatgttct ttggcagtga tatagttctt agacatcttc agaatgacta atttctccga   2160
gtggtgcata atcttatttt gtttgggagt aacaaatcgt ggaatatttt taaggaaaac   2220
tgttgtataa aactttacca tagtaacctt agaccttaga gaggtagctt tggagtgaaa   2280
ctttggctgc aataggctac tttgcaagcc ctccgtaaaa gtcagaggag agatcagtac   2340
agagctaaga gtgacatcaa atgaggactg tgggacccag atttgaagac ccaataaaaa   2400
tactcaactt tttaaaaaaa aaaaaaaaaa aaaaaaat                           2438

<210> 374
<211> 584
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (582)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (583)
<223> n equals a,t,g, or c

<400> 374
tgggatatct ccggagcatt trgataatgt gacagttgga atgcagtgat gtcgactctt     60
tgcccaccgc catctccagc tgttgccaag acagagattg ctttaagtgg caaatcacct    120
ttattagcag ctacttttgc ttactgggac aatattcttg gtcctagagt aaggcacatt    180
tgggctccaa agacagaaca ggtacttctc agtgatggag aaataacttt tcttgccaac    240
cacactctaa atggagaaat ccttcgaaat gcagagagtg gtgctataga tgtaaagttt    300
tttgtcttgt ctgaaaaggg agtgattatt gtttcattaa tctttgatgg aaactggaat    360
ggggatcgca gcacatatgg actatcaatt atacttccac agacagaact tagtttctac    420
ctcccacttc atagagtgtg tgttgataga ttaacacata taatccggaa aggaagaata    480
tggatgcata aggaaagacm agaaatgtcc agaagattat cttagaaggc acagagagaa    540
tggaagatca ggtcagagta ttattccaat gcttactgga gnng                     584

<210> 375
<211> 2738
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (762)
<223> n equals a,t,g, or c

<400> 375
ggccggctga gggcacttgc tcttgctgtt tctgcccctg ggttaacatt caagatggta     60
catgctgaag ccttttctcg tcctttgagt cggaatgaag ttgttggttt aattttccgt    120
ttgacaatat ttggtgcagt gacatacttt actatcaaat ggatggtaga tgcaattgat    180
ccaaccagaa agcaaaaagt agaagctcag aaacaggcag aaaaactaat gaagcaaatt    240
ggagtgaaaa atgtgaagct ctcagaatat gaaatgagta ttgctgctca tcttgtagac    300
cctcttaata tgcatgttac ttggagtgat atagcaggtt tagatgatgt cattacggat    360
ctgaaagaca cagtcatctt acctatcaaa aagraacatt tgtttgagaa ttccaggctt    420
ctgcagcctc caaaaggtgt tcttctctat gggcctccag gctgtggtaa aacgttgatt    480
gccaaggcca cagccaaaga agcaggctgt cgatttatta accttcagcc ttcgacactg    540
accgataagt ggtatggaga atctcagaaa ttggctgctg ctgtcttctc ccttgccata    600
aagctacaac catccatcat ctttatagat gaaatagact cctttctacg aaaccgttca    660
agttctgacc atgaagctac agccatgatg aaagctcagt ttatgagtct ctgggatgga    720
ttggatactg atcacagctg ccaggtcata gtaatgggag cnrccaatcg tcctcaggac    780
cttgactcgg ctataatgag aagaatgcct acaagatttc atatcaacca gcctgcttta    840
aaacagagag aagcaatcct gaaactcatc ttgaaaaatg aaaatgtgga taggcatgta    900
gacctgctag aagttgccca ggaaactgat gggttttcag gaagtgacct aaaagagatg    960
tgtcgagatg ctgccctcct ctgtgttaga gaatatgtta attctacatc agaagaaagc   1020
catgacgaag atgaaattcg gcctgttcaa cagcaggacc tgcatcgggc aattgaaaag   1080
atgaagaaat caaaggatgc agcatttcag aatgttttaa cacatgtttg tttagattaa   1140
gagtaaagat catttgtaca gttcagtgat ctagtttggt gtgtcctctt atcagttagt   1200
ggaaatagaa cggaaagagt gctctttaaa caatgaggga gctcagtgtt tatggtttta   1260
tactctgaat tctaagttat tgagatatag ttgttacata ggtggtatta ctgttggtca   1320
aaaatcatga ggaggaacag ttgaatccag cctgaacgtg ggtgcttgtg tttgaccttt   1380
tcagccatat attgtacagc cttatagaat ctaagctggt cttaaagtca taaatgattc   1440
attgggtcat tagtgagaaa cggggatgtg gttaggtgct ggttcctaga catgtgagta   1500
tgcgtttgtg tgtgtgcgtg tatgtatgtg tatattaaat gtatatatcc acacatttta   1560
tattgacatt ctgtagatat gtttgaatat agaaactttt tttaccccaa ctactgaatc   1620
caggagtacc aaataatata tagtaaaact aagatttaag gttgtgtcaa aaaggtacag   1680
tgattcagcc atttccattt gtcatttgtt tcaacctttt ttaagttgag tgtttttatt   1740
tctgcagtta ttagttggat cctccacatc ttgcatatat acatgggctc aattattatg   1800
tttgtcagga taatcaaatg aaaatactag ttcagtgatc agcattgaat ggttgttagg   1860
cagccatgtg ctcaacactg atttcacctc ttgagtataa actttttaaa tttaaattgg   1920
tttacatgaa agtggattaa aaggcctttc aaaagaatgg gtttgaaaaa cytcagtacc   1980
ctttaataca tgtacatttc tttccttttt tcatttaatg taacatgtct gttgtaacta   2040
tgtttcttaa atattatttt aaggttatgt gttctttaat tatggtcaaa tataatttgg   2100
tcaccaaaaa tgaaataata gtttaaaaca agtagctgtt actaagtgtg ctaaaaatac   2160
tcattttata attaatttta gttttcttag tatattatta taaattgtgc cctaagtcag   2220
gtacaaatgt acacatcaaa atgcccatat tgtatctatc tgtagtcgtt taatgtgaat   2280
tatatgtgaa tttttttcaa aattttacta accagaattc tgttataggc acctaaccac   2340
gcagcatgag gaaaacggca caacacaatc ttgaggtgcc ttctgaatca tcagattaaa   2400
ttatgcttca tatgtttttg cttttactgt atttctttaa aaactctaaa tctttattca   2460
tgtgtcactg gattaattta tctgataatg tgtctcacaa gaatctgtta gatcgtttat   2520
tcttcagttg tactttgaat ggtggggtgg aagtttcagg tgaacaatgg ataacaaaaa   2580
gcaagttatg gaagattgtg aagaggatgg aaaaactgaa tacaagatac caaaaatgaa   2640
aaaaagtgtc ccatttttaa taactatatt ctattatttt ataaatgtgt aataaagggg   2700
tccctcttta aaaaaaaaaa aaaaaaaaaa aaaaaaaa                           2738

<210> 376
<211> 1111
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (115)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1095)
<223> n equals a,t,g, or c

<400> 376
agcggcagtc gggtgggaag ccgtgtctcg cagtcgtgga ctcgtgcagc tggggcgtcy     60
gcakscgctc gtmacccgcg tratgctgtt tctggcgttg ggcagcccgt gggcngtcga    120
actgmctctc tgcggaagga ggactgcatt gtgtgcggcc gccgcgctcc gaggtccccg    180
ggcctctgtc tcccgggcgt cctccagcag cgggccttcg gggccggtag ccggctggag    240
tacggggcct tcgggagccg cgcgccttct ccggcgtccg ggtcgagcgc agatccctgt    300
ttattgggaa ggatatgttc gattcttaaa tacgccatct gacaaatcag aagatggaag    360
gctaatttat actggcaata tggcccgagc agtgtttggt gtgaaatgtt tctcttattc    420
tacgagtctg attggcctta catttctgcc atacattttt acacaaaata atgctatttc    480
tgaaagtgtg cctctgccta ttcaaatcat attctatggc atcatgggaa gctttacggt    540
gatcacccca gtgctgcttc actttattac aaaaggctat gtcattcgat tgtaccatga    600
ggccacaaca gacacttata aagccattac ctacaatgct atgcttgcag aaacgagtac    660
agtgtttcac cagaatgatg tgaagattcc agatgctaaa catgtattta ccacatttta    720
tgctaaaaca aaatcactgt tagttaatcc agtgctcttt ccaaaccgtg aagactatat    780
ccatctaatg ggttatgaca aagaagaatt tattttgtat atggaagaar ccagtgaaga    840
gaaacggcat aaagatgasa aatgagccta tttgttagtg ttcgtgctya aatgtgattt    900
acgttttaat gtataataat aaaattgcct tttgcattcc gttagtgact gattgttaaa    960
aataatttga aattatcaaa gcttttaatt tccagagaat gatgtttgtt tataataaaa   1020
caagctatgt ttgaaaacca aaatgtagta tctaccattc gtgttttaga aaggtatgtg   1080
aataaatatg ttctntgaag atcggactgg t                                  1111

<210> 377
<211> 1506
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (43)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1492)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1501)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1506)
<223> n equals a,t,g, or c

<400> 377
ctggaagaat tcgcgtggca ggagaggcgg ggcaattttg ctnagctttc tcgcgggctt     60
gcagctgcgg caagtgctgg cggcggctgc tcgcgcaagt cagctggcgt gggaactacc    120
ctttgtagct gagaacggct tgtttattgc tacaaagact ctattgacat tggtagcttc    180
agcggcagca gcttcttacg gtataaagct gttgcttcct gaagaggcta caagcatcct    240
tccctaggac tgctgtaagc tttgagcctc tagcaggaga catgcctcgg ggacgaaaga    300
gtcggcgccg ccgtaatgcg agagccgcag aagagaaccg caacaatcgc aaaatccagg    360
cctcagaggc ctccgagacc cctatggccg cctctgtggt agcgagcacc cccgaagacg    420
acctgagcgg ccccgaggaa gacccgagca ctccagagga ggcctctacc acccctgaag    480
aagcctcgag cactgcccaa gcacaaaagc cttcagtgcc ccggagcaat tttcagggca    540
ccaagaaaag tctcctgatg tctatattag cgctcatctt catcatgggc aacagcgcca    600
aggaagctct ggtctggaaa gtgctgggga agttaggaat gcagcctgga cgtcagcaca    660
gcatctttgg agatccgaag aagatcgtca cagaagagtt tgtgcgcaga gggtacctga    720
tttataaacc ggtgccccgt agcagtccgg tggagtatga gttcttctgg gggccccgag    780
cacacgtgga atcgagcaaa ctgaaagtca tgcattttgt ggcaagggtt cgtaaccgat    840
gctctaaaga ctggccttgt aattatgact gggattcgga cgatgatgca gaggttgagg    900
ctatcctcaa ttcaggtgct aggggttatt ccgcccctta agtagatctg aggcagaccc    960
ttgggggtgt aaaagagagt cacaggtacc ccaaggagta gatgccaggg tcctaagttg   1020
aaaatgatgt cgattggggg cgggggacac tgtatttgat atttgtgatc agtgatcatt   1080
gttcaactgc gaaatagagt gtttgctttt gataatggaa aattgtattc gttttaaaat   1140
tccgtttgtt gagaataaca atatgtttaa aaatataatt gaacaaattt ttttctttgt   1200
ttcctgtcat tgacatttag tataacagtt ttgctaacgt tctaaaatga agtcgttcca   1260
tcataatcta tgatcttgta cagcacttat agaaataagc tgttcttttg aagttgaaat   1320
acccagtaaa atgttgaaga aggatggagg atttcttcat atctgacgtt tctgaaaccc   1380
tttgtgtctg ctgttgtgtg aagattgaca tttaccatga ttttccttag ttactgcaga   1440
acatagagaa aaataaaagc ctaacgaata gtaaaaaaaa aaaaaaaacc tngggggggg   1500
ncccgn                                                              1506

<210> 378
<211> 457
<212> DNA
<213> Homo sapiens

<400> 378
agccaagtta gagatgactg ctgtggctga cattttcgac cgagatgggg atggttacat     60
tgattattat gaatttgtgg ctgctcttca tcccaacaag gatgcgtatc gaccaacaac    120
cgatgcagat aaaatcgaag agaggttaca agacaagtgg ctcagtgcaa atgtgcaaaa    180
aggtttcagg tggagcagat cggagagaat aaataccggt ttggggattc tcagcagttg    240
cggctggtcc gtattctgcg caaccgtgat ggttcgcgtt ggtggaggat ggatggcctt    300
ggatgaattt ttagtgaaaa atgatccctg ccgagcacga ggtagaacta acattgaact    360
tagagagaaa ttcatcctac cagrgggagc atsccaggga atgaccccct tccgytcamg    420
gggtcgaagt ccaaaccatc ttcccgggca gcttccc                             457

<210> 379
<211> 922
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (249)
<223> n equals a,t,g, or c

<400> 379
gttttttttt tttttttttt ggaattaatt actcttttat tagcacaaaa taacagcaac     60
ctagcagccg cacgscccga gaataagtta aggcacagag caggcgacgg gcggctttcc    120
cagggccagg cctgcatgcc ccgaacttcc tgagcaaact ccctaggggc tggggtttcg    180
agggtcctgg agggcctctt cccttgagat gaggggaacg gaacagggca agaggggcgc    240
ccccatggnc gcaaggggtc cacgctgcgc cgcgatcact tctcgaagta gggcaggtag    300
aagaactgga agccccggtg gcccttgacc gcgcagtaga tgaagatcac gtgatagact    360
ccaggcacca acaacaggaa gcccggcacg aagaagatgg cgctggagac acctggagag    420
ggggtcgcct ccagtcccac gccgaccagg atcagcacca gccccagcag caggagcagg    480
aaggaggcca gcaccactcg gcggttcttc tggatcaaag ggtgttgggt ccagctgcag    540
caggtgttgt aggagcgctg ggtgctgctg ctgatggtgc tgaaggacca ctgggagctg    600
cggatggaag ttcggctgga atccctggtg ccgactcccc catccggctc cggagaggcc    660
tgggctccat cctcatcgtt ctccaggttc tggtagcgca gccgggactg cttgtcctcg    720
tcagccacct cgaaccgggc ccgacgctcg aagtgcagcg gcccaaagcg cgcgaccccg    780
ctggactcgc ccagggcccc cgtcctccag ggacagctcg aaggcatcat caatgctgaa    840
ctggggccgg gcggcgctca tggccccggc ccgctcaggc cgtgcgccgc cgccatctgc    900
gcccaccgga cgcgtgggtc ga                                             922

<210> 380
<211> 2439
<212> DNA
<213> Homo sapiens

<400> 380
cttttttttt tttttttttt tttttttttt tttttggagt aaatacattt attgataccc     60
atttcatata tagttcaatg aaataatcta taaatataaa aagcattttt cttttggata    120
tcaccatggt ccatgtaaat actcaagtca gaatcatctg caggaagcac tccaagtcac    180
actgttagct ttacagacct gaatatacat attgcattaa acagtggcac ttatgtactc    240
aagtggtcca gtggctttgg aatatatgtc tactgggcat gtggaataga aataatgtgt    300
taggtttaaa tcaatggaaa gggtatcaac catcaacaaa agcaacaatt atgaattcat    360
atcctaggca aagaaagtac cacagttgac acttggtgtc agaatactgg agacaaagta    420
tgtaaaacaa tgcctgttgc agcaccacgt gctcactcca actcccagtg gacagtcccc    480
caatgcctta gggtcactcg tggtcaacca aatgcaatca agaagctcga tagcttagaa    540
taaaaggtct gtagaggctg atatcaagat taaagtaagc taaacatttc agtgacacaa    600
tgagtttcct ccctagaagg ggactgtggg aaaactttta attccctttg ttacactgag    660
catgatcatt tatctaatgc agaagaaaga acccagacat ctggtactca gaacataggt    720
gcaaaaattt tcttccattt caaagttttt tcaatacttc cgagggaact aatgcaacca    780
ccgttgagcc ttgctctcca cctgatgcag cataaaattt tctctcattt cttcaatata    840
ggaatgtctt gctgcagact atgtgtcttc cgagttagca agcaaatgcg tttaaaaggt    900
cttagttgtg caatgtccaa aactgaaatc tgagaggcag tgttagaact taagcaaggc    960
agaattttta gagtctactc aaatgaaagc ctaagtgaag catataaaaa ttcagtcttt   1020
tctattattt tcaactggaa ttgatggcaa cattccctgg taaggatggg taactggtgt   1080
tatctccagg tccaaaatat cccaactact taaaggggac ccaaaagagg agaaacacac   1140
acttgagttc tgtggtctcc agaatttttt tttttttttt tttgccattt tcaaaaaaga   1200
tatagtagct tcagttgtac accaccagtt gaaggggttt tcatccaaat gagaaactct   1260
accccttgtc tctagtggaa caggcaccag attcccacaa gcagcagctc ccatgtcctg   1320
tagcacgtgg catccgaccc tggagtgaag agtaagctgg cacagagccc cgacgctggg   1380
attcagacta gatggcgttt cgtggcgtgc cattgtgtgt cagcgctttc agactggagg   1440
cactagtctg gtgaccacag ctcctgtgag aagtcacacc cacctcaaaa acctcatgaa   1500
tagcttttcg gaaacagtgg aagttgtagt ctattaaacc ttttctttca aagctttctt   1560
cccttagaat gcagaccagt gccaaaaatt tagtcacctc ctttaaataa aggacagttg   1620
tattattcag cttgataatt gccatagatt ctttgtcata agcacttcca cttccatctt   1680
cctttaaccc atatatacaa gacacatcaa ttacaacatc gatcatgtca cagcaaagtt   1740
cataagattg catatccaca ggggaactgt ctgttgcaat gtagattttg ctgacaacat   1800
caaagagaaa agctttttca atacctgaat ttgatataaa gatatttaat aggttttcca   1860
aggtcggcag ttgtggaatg agtttctgca ccaccttact aaaggcttca aatattgaat   1920
ggtcatagat actagtcaga taaaagctaa gatggagttt ttctagccca gcatctgcaa   1980
ggtcatcatt ggccctttga tgaatgtccc tctgtgtttc tattttgtga tcatcagaca   2040
gaccatcaac tttgtgaata aaaacctcaa aattcatgtc tgggttaact ttgtaggctt   2100
tagaaacagt aatgtgaagt cttgttaaag cctccatgta gtcatcctgt gcgtcaatga   2160
cgtatatcaa tgctcctgtt cccctgaaga tcatctcata gtcaaaggtt gggtcaaaaa   2220
agtccatttg cccaggaaaa tcccatatct ggaaattcac aaaggagcta ttggaaatgt   2280
catccttata aatcttgttg gtactttcca aaaagagggt ctcgttgggt gacatcttat   2340
gaaacaccac cttctggatg gaggacttgc cgctgcgccg gagtcccatg agcagaatcc   2400
tcggcttgga gctgtcagcg ccccccggac ctcgtgccc                          2439

<210> 381
<211> 846
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (838)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (841)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (845)
<223> n equals a,t,g, or c

<400> 381
gacagtacgg tmcggawtcc cgggtcgacc cacgcgtccg aagtcgcggt gcagcggtgg     60
gcggcatgtc tgtggccggt ggggagattc gtggggacac ggggggagag gacactgctg    120
ctcccggccg gttcagcttc agcccggagc ccacgctcga ggacatccgc cgcctccatg    180
ctgagtttgc tgcggaacga gactgggaac agttccatca gcctcggaat ctcctcctgg    240
ccttggttgg ggaagtgggg gagctggcag aactctttca gtggaaaacc gatggggaac    300
ctggccccca aggctggtcc cccagggaac gggcagccct tcaagaggag cttagtgacg    360
tcctcatcta cctggtggca ttagcagccc gctgccgtgt ggatctgccg ctagcagtgc    420
tctccaaaat ggacatcaac cggcgacgct acccagccca tctggcccgc agctcttccc    480
gcaagtatac agaattgccc catggggcca tctctgaaga ccaggctgtg gggcctgcgg    540
acattccctg tgactccaca ggccagacct caacctagaa agatggccac aggacttgca    600
actcagggtg gtgtctgaag agcagagagt ggcctggccc tggagccttt ttctagtctt    660
ttcagaatag atcatgggcc tgaggcytcc acttcttgag gtctgaggcc cagcagcctc    720
tagaaggtag cctcctggtg tttgttctcc cagtaaaatg gttttgggcg ataaaaaaaa    780
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaantc    840
naggng                                                               846

<210> 382
<211> 771
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (200)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (205)
<223> n equals a,t,g, or c

<400> 382
gttcttctaa atcaggaatg gattgaaatc taatgaaccg aaactttggg tacttcggcc     60
ttcaaggggc tcctttattg agaatcaatg tcttctccta ggtaattgat caccctagac    120
ccagggacac ccaattcatc gtaatcatca tgaataatca aaaagtggta gctgtgctac    180
tgcaagagtg caagcaagtn ctggntcagc tcttgttgga agcgccagat gtgtcggaag    240
aggacaagag cgaggaccag cgctgcagag ctttactccc cagcgagtta aggaccctga    300
tccaggaggc aaaggaaatg aagtggccct tcgtgcctga aaagtggcag tacaaacaag    360
ccgtgggccc agaggacaaa acaaacctka aggatgtgat tggcgccggg ttgcagcagt    420
tactggcgtc cctgagggcc tccatcctcg ctcgggactg tgcggctgcg gcggctattg    480
tgttcttggt ggaccggttc ctgtatgggs tcgacgtctc tggaaaactt ctgcaggtcg    540
ccaaaggtct ccacaagttg cagccagcca cgccaattgc cccgcaggtg gttattcgcc    600
aagcccgaat ctccgtgaay tcaggaaaac ttttaaaagc agagtatatt ctgagcagtc    660
taataagcaa caatggagca acgggtacct ggctgtacag aaatgaaagt gacaaggtcc    720
tggtgcagtc ggtctgtata cagatcagag ggcagattct gcaaaagctg g             771

<210> 383
<211> 715
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (536)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (573)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (578)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (625)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (688)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (695)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (698)
<223> n equals a,t,g, or c

<400> 383
ggccatgggg ggaaagcagc tggacgagga tgacgaggcc tacgggaagc cagtcaaatm     60
cgacccctcc tttcgaggcc ccatcaagaa cagaagctgc acagatgtca tctgctgcgt    120
cctcttcctg ctcttcattc taggttacat cgtggtgggg attgtggcct ggttgtatgg    180
agacccccgg caagtcctct accccaggaa ctctactggg gcctactgtg gcatggggga    240
gaacaaagat aagccgtatc tcctgtactt yaacatcttc agctgcatcc tgtccagcaa    300
catcatctca gttgctgaga acggcctaca gtgccccaca ccccaggtgt gtgtgtcctc    360
ctgcccggag gacccatgga ctgtgggaaa aaacgagttc tcacagactg ttggggaagt    420
cttctataca aaaaacagga acttttgtct gccaggggta ccctggaata tgacggtgat    480
cacaagcctg caacaggaac tctgcccagt ttcctcttcc ctctgctcag ctctgngacg    540
ctgctttcat ggaccaacat tactccaccg ggngctcnca gggatcacca atgaccaccc    600
accatacagc aggggaatca gcggncttta ttgacagcct caatgcccga gacattaatt    660
gttaaagatc tttgaagatt ttgcccgncc tggtnatngg atcttggtgc ccttg         715

<210> 384
<211> 549
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (359)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (414)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (468)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (470)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (532)
<223> n equals a,t,g, or c

<400> 384
gcaagagcag aacccggcat tgagtatttt gaagatggag ccaatgtccc tggtctgccc     60
ctgcctcggc atcccccacc acctctggca tccatacccg cggtgggtgc tgtaacggca    120
tctgggcttt gtcatctcct ttgcagaaca tcgtagctgt gggagctggg ttctgcgacg    180
gcctccgctg tggagacaac accaaagcgg ccgtcatccg cctgggactc atggaaatga    240
ttgcttttgc caggatcttc tgcaaaggcc aagtgtctac agccaccttc ctagagagct    300
gckgggtggc cgacctgatc accacctgtt acggagggcg gaaccgcagg gtggccgang    360
ccttcgccag aactgggaaa ggtagcccct cactgctctc cgcaccccct cttnctcact    420
tgagactcct gcttggggtg aactggaacc catggagatt tatgccancn ttattgctgg    480
gatggtccgt tgcctgctgt ttttacttga ctctttggtc ttatctttgg gntttaactt    540
cttggttca                                                            549

<210> 385
<211> 995
<212> DNA
<213> Homo sapiens

<400> 385
cggggtgcct ggggcagacg aggccggctt ctccgcggac agctagggag agtgtcctgg     60
gtgtcagcca gaacatgtct ttcaacctgc aatcatcaaa gaaactgttc attttcttag    120
gaaaatcact gtttagtctt ctggaggcta tgatttttgc cttactccca aagccacgga    180
agaacgttgc tggtgaaata gtcctcatca caggtgctgg aagtggactc ggaaggctct    240
tagccttgca gtttgcccgg ctgggatctg ttcttgttct ctgggatatc aataaggagg    300
ggaatgagga aacatgtaag atggctcggg aagctggagc cacaagagtg cacgcctata    360
cctgcgattg cagccaaaag gaaggagtgt atagagtasc cgaccaggtt aaaaaagaag    420
tcggcgatgt ttccatccta atcaacaatg ccggaatcgt aacaggcaaa aagttccttg    480
actgtccaga tgagcttatg gaaaagtcat ttgatgtgaa tttcaaagca catttatgga    540
cttataaagc ctttctacct gctatgattg ctaatgacca tggacatttg gtttgcattt    600
caagttcagc tggattaagt ggagtaaatg ggctggcaga ttactgtgca agtaaatttg    660
cagcctttgg gtttgctgaa tctgtatttg tagaaacatt tgtccaaaaa caaaagggga    720
tcaaaaccac gattgtgtgc ccctttttta taaaaactgg aatgtktgaa ggttgtacta    780
caggctgtcc ttctctgttg ccaattctgg aaccaaaata tgcagttgaa aaaatagtag    840
aagctattct acaagaaaaa atgtacttgt atatgccaaa gttgttatac ttcatgatgt    900
ttcttaaaag gtaattacat cagcttctat tacttcccta acatgccagt ctacagttta    960
ctccaaatcc cmccaggaaa aaccactttt aaaaa                               995

<210> 386
<211> 2032
<212> DNA
<213> Homo sapiens

<400> 386
ggcacaggcg gccgcccgcg cgccaagttc ctcagccctt ggctcctgcc cagtgtttag     60
ggtgttggcg gagaaaaggg gaagagtcat cgcctgtcgg ggctaggata tgatgggtga    120
gaggtgtcaa accaaattct ctcggtttgg aaacggagaa aatctaaaaa tgaggatgtg    180
aggaaagagt ccgctctcaa ggcgcgttgt ggtctatccg agccccgtcc cctgggctcc    240
ctcgggctgg ggtgaggcgg gcagctacgc gtggggtagg accatcttac gctgggaccc    300
cgccaaggag ccccaggaag taggtgaaag ggcaggggcg tggctctcgg ggcgccaccc    360
acgctcttga aatctgggtg attgcgagcg gccgctcagc gtcccccaca ccacagaccc    420
gcgccgccga cgacccagca gccgccatgg ctctgctccg aggtgtgttt gtagttgctg    480
ctaagcgaac gccctttgga gcttacggag gccttctgaa agacttcact gctactgact    540
tgtctgaatt tgctgccaag gctgccttgt ctgctggcaa agtctcacct gaaacagttg    600
acagtgtgat tatgggcaat gtcctgcaga gttcttcaga tgctatatat ttggcaaggc    660
atgttggttt gcgtgtggga atcccaaagg agaccccagc tctcacgatt aataggctct    720
gtggttctgg ttttcagtcc attgtgaatg gatgtcagga aatttgtgtt aaagaagctg    780
aagttgtttt atgtggagga accgaaagca tgagccaagc tccctactgt gtcagaaatg    840
tgcgttttgg aaccaagctt ggatcagata tcaagctgga agattcttta tgggtatcat    900
taacagatca gcatgtccag ctccccatgg caatgactgc agagaatctt gctgtaaaac    960
acaaaataag cagagaagaa tgtgacaaat atgccctgca gtcacagcag agatggaaag   1020
ctgctaatga tgctggctac tttaatgatg aaatggcacc aattgaagtg aagacaaaga   1080
aaggaaaaca gacaatgcag gtagacgagc atgctcggcc ccaaaccacc ctggaacagt   1140
tacagaaact tcctccagta ttcaagaaag atggaactgt tactgcaggg aatgcatcgg   1200
gtgtagctga tggtgctgga gctgttatca tagctagtga agatgctgtt aagaaacata   1260
acttcacacc actggcaaga attgtgggct actttgtatc tggatgtgat ccctctatca   1320
tgggtattgg tcctgtccct gctatcagtg gggcactgaa gaaagcagga ctgagtctta   1380
aggacatgga tttggtagag gtgaatgaag cttttgctcc ccagtacttg gctgttgaga   1440
ggagtttgga tcttgacata agtaaaacca atgtgaatgg aggagccatt gctttgggtc   1500
acccactggg aggatctgga tcaagaatta ctgcacacct ggttcacgaa ttaaggcgtc   1560
gaggtggaaa atatgccgtt ggatcagctt gcattggagg tggccaaggt attgctgtca   1620
tcattcagag cacagcctga agagaccagt gagctcactg tgacccatcc ttactctact   1680
tggccaggcc acagtaaaac aagtgacctt cagagcagct gccacaactg gccatgccct   1740
gccattgaaa cagtgattaa gtttgatcaa gccatggtga cacaaaaatg cattgatcat   1800
gaataggagc ccatgctaga agtacattct ctcagatttg aaccagtgaa atatgatgta   1860
tttctgagct aaaactcaac tatagaagac attaaaagaa atcgtattct tgccaagtaa   1920
ccaccacttc tgccttagat aatatgatta taaggaaatc aaataaatgt tgccttaact   1980
tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagggggagg gg           2032

<210> 387
<211> 499
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (447)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (466)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (467)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (469)
<223> n equals a,t,g, or c

<400> 387
ggcacgagtg aagctgaagt actgcttcac ctgcaagatg ttccggccac cccgaacctc     60
acactgcagt gtctgcgaca actgtgtgga acgatttgac catcactgcc cctgggtggg    120
caactgtgtg gggagacgga actatcgctt cttctacgcg tttattctct ccctctcatt    180
cctgacggcc ttcatcttcg cctgtgtggt cacccacctg acgttgcgcg ctcagggaag    240
caacttcctc tccactctga aggagacacc agcaagcgtg ctgggagttg gtgatctgct    300
tcttctccat ctggtccatt ctgggcctct cagggtttca cacgtacctc gtcgcctcca    360
acctgactac taatgaagac atcaaaggtt cgttggtcca gcaagagggc ggtgagcctc    420
ttgtcaaccc tacagcataa agtattntca ccaatggcgg gtgggnntng ggccctaact    480
tccagctatt gacgggggg                                                 499

<210> 388
<211> 1516
<212> DNA
<213> Homo sapiens

<400> 388
cccaaagtgc tgcagttaca ggcgtgagca ctgcacctgg cctcatgttt tttaaataat     60
tgccttttat atttaccctt tttgtcatca ctttagaatg aaaattccca tttaaatctg    120
aaagttacct taatagtcct cttgtgttat taggacagta ttattatagt acttatttat    180
tttattttag atttaaagtt atcttctctt tttctttttt cttctgctgc ttttagggac    240
aattaaaact gggaaactat gaaacatgga acattttatc ctacctgaaa gtaaacgagt    300
aattgtgaag cataagacac tgaggctaat acaactctgt cttcatgtgt tgactgcctg    360
gcacatagta ttcattctct tccctttaac atagaagtgt ccagctgcgt acagtctagt    420
aaccagcaac tgtaaacgaa cctgtgcctc taacaagcga ttctaaacca cctatgagta    480
tttcttttag ggctcactta aatacatgtt tgtatatact gtattctagc cagaataatt    540
ttagatctga tcaggtagta gctaaaatta gaaaaaaaca aaatagatgc ttaaagaatt    600
tgcatccatt tttgagtcta aatcttttaa aatatactga gatccacatc tagtgaaatg    660
tcagtgtcaa aatattatag attatagcta aaatccagat taatactcat ttggggtttt    720
ttatagtgga acttcatagt aatacaaaaa gcagattgtc ttcctgtctc cgctgctccc    780
acagtaggta ttgaaactgg taaaatcagt tttttgatag tgtgtgtata taagaaaaaa    840
tagatacaca cattcttttt tctcagtcaa cacattgatt gaacactctg gcaaagatgc    900
tgtggtggat gaggttggag ttcgaaagaa gaagcaagcg ctggcctggc cttgaaagaa    960
ccgaagtctt tcccattcac ttctctagaa agctgccaag acagaggcag aaagaaatgg   1020
atgatagttc tgtcaagcac acttctgttc tcttagaact tagaagtgtt tctaagagaa   1080
cagaagtaat aagagaaaca gttacgtgtg gaattcaaca tctttggttg gaacgcattg   1140
gctttttttt tcttgttttg atagaaatgg aattaagcaa aagtagtttt tgtcttttct   1200
gttgtcttca aattttatgc cttttatttt taatttaatc ccgttcaatt atttaattgt   1260
tatacattga cattaactgc tgtattttga ctttgttcaa taattttgtt ctttcagggc   1320
tagaaataaa ctttttaaaa aaagtgtgca tttttccctt tcctaaactt ttattctttc   1380
ttttgatcag cgtaaaagaa tattttaatg tcttttgata gcataaaaga atatttaaat   1440
gtcttaatag gttttcaaag aacatttagt atttttagtg ataaatgttt taaacctttt   1500
aaaaaaaaaa aaaaaa                                                   1516

<210> 389
<211> 2127
<212> DNA
<213> Homo sapiens

<400> 389
cacaggcaga gatcaagtac aaaggtggta caacatcttg gccctgcaac tgatttttat     60
aaraaacttg cattagattg ctcgggacag caaactgcag tggatttgtt ccttttaagt    120
tcacagtatt ctgatcttgc ttctctagct tgcatgtcca agtattctgc agggygcatc    180
tattattatc catcattcca ctatactcac aatccttcac aagcagaaaa gttacaaaaa    240
gacctaaaac ggtatctcac aagaaaaatt gggtttgaag ctgttatgag aataaggtgt    300
actaaaggtc tttcaatgca cacttttcac ggtaacttct ttgtccgttc tactgatttg    360
ttatcccttg ccaacatcaa tcctgatgct ggatttgcgg tgcagttgtc aattgaagaa    420
agtttaacag atacttcctt agtatgtttt caaacagccc tattatatac atcaagcaaa    480
ggtgagcgga gaattagagt acatacactt tgtttgccag tggtaagttc actagcagat    540
gtatatgcgg gagtggatgt acaagctgcc atctgccttc tggcaaacat ggctgtggat    600
cggtccgttt catcaagtct gtcagatgca agagatgcct tagtgaatgc tgtagtggac    660
tcattgtctg catatggctc aactgtctca aatttacagc actctgcatt gatggcgccc    720
agctccctca agttgtttcc tctctatgtt ttggcccttc tcaaacagaa agcatttaga    780
acgggtacaa gcacacggct ggatgatcgt gtatatgcca tgtgtcagat aaagtctcag    840
ccacttgttc atctaatgaa aatgattcat cccaacttat acaggataga cagattgaca    900
gatgagggtg cagtacatgt taatgacagg attgtaccac agccacctct tcaaaaattg    960
tctgcagaga agctgacaag agaaggtgct ttccttatgg actgtggctc tgttttttac   1020
atttgggttg ggaaaggctg tgacaataac ttcatagagg atgtgcttgg atatactaat   1080
tttgcatcaa taccacagaa aatgacacat cttccagagc tagatacact ttcatcagaa   1140
agagccagat ccttcataac ttggcttaga gacagcagac cattaagtcc aatccttcac   1200
atagtaaaag atgagagtcc tgccaaagca gaattttttc agcatttgat tgaagaccgg   1260
acagaggctg cattttctta ctatgaattt ttgcttcatg ttcagcagca gatttgtaag   1320
tgaagtagaa taaaattgaa taagaaaaag atctataacc taggtaaagc ataatctgtc   1380
agagaagcgc gtgagaaatt tgaaatgaag gcatttgtta atacaagatg caacgcacag   1440
cactctgtct gaggctttgg taaaaagtaa aggggaagaa agaacttgac agatcttttt   1500
caactcaaat taatggtaac gatgatgctg tttcaccaag tatattttga attggtttct   1560
acacatttcc agtagtatgg cagtacagtg ctctgttcat tgcaagctgg caaatttatg   1620
tagctatgtg gaatgatatg tcataatgta aaattagata aattcttttt tcttataatt   1680
aatataacat ttctggactt gaactctggc aagagatgcc aaaaggcatt ggtaccgtgt   1740
tatttgttta tatgaattac tttttaacaa ggaatgtttc ttattcatta aatgaattca   1800
acattttctc tgtaaaaaca atagagtttc agtacatgaa ctatagaaaa aaatctatat   1860
ataatgtaca taaatgttac atttgtaaag aaaatgtaaa aatgtaacta tagcatatga   1920
attgcttaaa ctgtgctgca ttgttggatg acaactcttt ttgtcacagt tagagaatga   1980
ggttgactaa tgcatattat gaattgagtc cacaaaggaa cacaaaactc tttgtaattc   2040
tgttaaatct tttatgtaga tttatttatg atcagcctac taattaaaac tatttcgctt   2100
gacagtaaaa aaaaaaaaaa aaaaaaa                                       2127

<210> 390
<211> 2375
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (920)
<223> n equals a,t,g, or c

<400> 390
cggcagcgna ccaagatggc ggcgccctgt gagggacaag cgtttgccgt agggttgaaa     60
agaattgggg tgcagtagtt cgctccccag aagggacccc ccagaaaatc cggcagctga    120
tagatgaggg gattgccccg gaagagggag gcgtggacgc gaaggacacg tctgccacat    180
cccagtcagt taatggatca ccccaagcgg aacaaccttc attggaatct acaagcaaag    240
aagccttctt tagcagagtg gaaacatttt cttctttgaa atgggcaggt aagccctttg    300
agctgtctcc actcgtctgt gcaaaatatg gctgggtcac agtggaatgt gatatgctca    360
agtgctctag ctgtcaagct tttctctgtg ccagtttaca accagctttt gactttgaca    420
gatataagca acgatgtgct gagctgaaga aagccttgtg tactgcccat gagaagttct    480
gtttctggcc agacagccca tccccagacc gatttgggat gttgcccctg gatgagcctg    540
ctattcttgt tagtgaattc ctagatcgtt ttcaaagcct ttgtcacttg gacctccagc    600
ttccttccct aaggccggag gacttgaaaa ctatgtgctt gacagaagac aagatcagtc    660
ttctcctaca cttgcttgaa gatgaacttg atcaccgaac tgatgagaga aaaactacaa    720
tcaaattagg ctcagacatc caagtccacg tcactgcctg tattctctct gtgtgtggct    780
gggcgtgtag ttcctctttg gaatccatgc agctctccct gatarcatgt tcgcaatgta    840
tgargaargt ggggctctgg ggcttccagc agattgaatc gtccatgact gacctggatg    900
catctttgcc tgaccagctn cccaatccca ggccttgagg ggcgaccaga gcgcttacct    960
ctggtgcctg aatctcctcg gaggatgatg acccggagcc aggatgccac tttctcccca   1020
ggctcagagc aggctgaaaa gagccctggt cccattgtct cwcgaactcg gagctgggac   1080
tcttccagtc ctgttgaccg tcctgagcca gagctgctag ccccaccacc agaactcgcc   1140
cagtgacccg aagcatggga acaggagaca cccctggcct ggaggtacca tctagccctc   1200
tgcggaaagc aagcragctc gcctctgctc ctccagcagt tcggacacat cttcccgaag   1260
cttctttgat cccacctctc agcatagaga ctggtgccct tgggtgaata tcacacttgg   1320
caaagaaagc agggagaatg gtggaactga accagatgcc agcgccccag cagagccagg   1380
ctggaaagca gtgctgacca tcctcttggc gcacaaacag tctagccagc cagctgaaac   1440
ggactccatg agtctctctg agaaatcaag gaaagtattc cgaatatttc ggcagtggga   1500
atctctgtgc tcatgctgaa gatactccag cgccttcctg gagatagctg gaatgagagt   1560
gactttttga aaaattaagg ctgagttcct ttcggtcagc tgacactaag tttttcctgt   1620
tctgggttaa tcataaggag ccccctgcca tagcaaaggc agtgagtgtc aactatctgc   1680
atctggctga gagagacccg tttcctttca gggatgtgga cagggtaagg gcagcaagca   1740
tggttctgtt aaaggagtgt ggggttaaca gactagaagg aagactaagg acctgaccac   1800
ccatttcagc atcttcaatg tggagcagtg ttctgaggac tcttctatcc taggactatg   1860
acagtgtgta ttaataaaat atttgctaag attctcattg ttggagaact gttttccccc   1920
ttgccctgtg ggccggagaa acttcagtgg aacattcaac ttttgatttt cagattggct   1980
gcaaagcctw aaatttgkga ttccagtcaa ggaggtataa tctttcctwa accaaaagca   2040
agatgatttt cattatgcca ccaggaaatt tcctggtgtg ttatagtgaa tggtcaactg   2100
ataattttct ccttgctttg ataataacag aataaaacaa cgtaatgggg aggaaggcac   2160
ttcagaagar acccctytcc atgtgccatt gaatgcatga gtcccccart tgggcttccc   2220
caagactcgt tgcttttggg ggatcatcag tttttgtggt agagaaggtg gaccctgaac   2280
tgcccactga taaagtaacc atgacctagc aaaggctaga aagtgattat tctctgatat   2340
ggccatgttt ttcgtcactg agattgtttc tcgtg                              2375

<210> 391
<211> 867
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (49)
<223> n equals a,t,g, or c

<400> 391
ccgcctcgtt gtgggtggag tgcggcagnc agaggctccn ccagcaagnt gaggcctgag     60
gtcakctgat acctgcacct tctccccaag ccagcgtgga ccctggtgtc tatggtgaag    120
ctgggccctc ccaccctgag ccttcctaga cccttggact ctcagatgca gggcccttgg    180
ctctggcctc tcacccccaa ggctgtctct ggccctgccg agcctatggg agtcccggga    240
cagagtgccc actcccctct acttgctgct ctgggcctcc ccacctttcc tggggtctcc    300
acattcccac tagtgggtct tatgtgtgtc tgtgtcttct ccttaaacac tcgccctgga    360
gtctgttctc acacctgtgc gcaggtttgc acactcaagt tctcatgggc aggctcaggt    420
ctgtcccgct gccctgggca cgaggtctcc tgaggacctg ggcctgttct gctcctagga    480
gacctgagcc cgttaccgcg tgactcccac catccagctc gcgctcctcg tggattcagc    540
catgcatgga ctggggtgtt ccctggccca tggtcacctg tgcccctcgt gtctcctcac    600
atgggtgtct gtggttctct cctgtgtaaa tgtcacgccc camccctgtt tcatgtgggc    660
actaacacgt gtgcgttcct ggcgggcaca ctcaggaccg tgcctcacag ggcccactcc    720
ctgcctatgc ctccctcttg gggggccgag gagggcggct gctctgtcat gagaatgtac    780
ggcccgtgga tgattaacgg gcctttttca cttagaagct gcacattatg gagcattaaa    840
cacttttgtc ataraaaaaa aaaaaaa                                        867

<210> 392
<211> 1501
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<400> 392
ggtcagntga gagacagggc tacgtttcag ggagggaaac agattcagca gcggcagcag     60
ctggagaagg tcgtggagca gcaccttgcc tgcagggtgt tctgagaatc agccatgtca    120
tccctgtacc catctctaga ggacctaaaa gtggaccaag ccattcaggc ccaggtcaga    180
gcctcaccca agatgccagc cctgccagtc caggcaacag ccatttcccc accaccagtt    240
ttgtacccaa acttggcaga actggaaaat tatatgggtc tttccctctc cagccaagaa    300
gtccaggaga gcctgcttca gattccagag ggtgacagta cagcggtctc gggccccggg    360
cccggccaga tggtggcacc ggtaaccggg tacagcctgg gcgtgcggcg agctgagatc    420
aagcccgggg tgcgcgagat ccacctgtgc aaggacgagc gcggcaagac cgggctgagg    480
ctgcggaagg tcgaccaggg gctctttgtg cagttggtcc aggccaacac ccctgcatcc    540
cttgtggggc tgcgctttgg ggaccagctc ctgcagattg acgggcgtga ctgtgctggg    600
tggagctcgc acaaagccca tcaggtggtg aagaaggcat caggcgataa gattgtcgtg    660
gtggttcggg acaggccgtt ccagcggact gtcaccatgc acaaggacag catgggccac    720
gtcggcttcg tgatcaagaa ggggaagatt gtctctctgg tcaaagggag ttctgcggcc    780
ygcaacgggc tcctcaccaa ccactacgtg tgtgaggtrg acgggcagaa tgttatcggg    840
ctgaaggaca aaaagatcat ggagattctg gccacggctg ggaacgttgt caccctgacc    900
atcatcccca gtgtgatcta cgagcacatg gtcaaaaagt tgcctccagt cctgctccac    960
cacaccatgg accactccat cccagatgcc tgaagccact ggagggcagg gcaggcaggg   1020
ggggcttccc gccctcctgc agcaaagggc aaccacccty ggatgatggg ttgcagccgg   1080
cctgctgctt aaggtggggg ctgccatgag gggggcgtgt ccaggagggt gaccatggga   1140
tggcttatac acacaggcct ccttggagcc tcagactcca agctaggctg aggctcaggc   1200
agggcccaca ggcagccgat tctcttgtgc tgatttaaat gctggacacg gaggcaggct   1260
gtttaaacgc tgcttaaagt cgcaactggg cccctttcaa gaaattttgc tctaccagga   1320
aaacagttac acattttaag agaacagagc tacgttcttt gtgagagctt tttccttgsc   1380
ttgacttgct ctttgtcaca gactgcataa gttgtcagcc ttgactatct tttgaataaa   1440
gatttgattt taaacaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1500
a                                                                   1501

<210> 393
<211> 1048
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (388)
<223> n equals a,t,g, or c

<400> 393
ggacccacgc gtccgcccac gcgtccgcta tatcataaaa gttatttccc accccatttt     60
atcttgacaa ccgtgtttgc atttctgtaa aacttctaca acttctggtg tcagaactgt    120
ccagaagatg gtactgttaa ctgttatttc ctttgatgtt ttgattttga agtttagctc    180
tcatgcaaat gtttcaggcr tacatacata ggcagaaagc aatttttagg tgatttgtct    240
gtttcttgga tgaaatataa agcaagcttt aatgttctga cttgttcatt tgaaatacaa    300
aaaagtaagt gaattttaat gttttgcatt aactaaagaa atctgaagat taatgttgag    360
gaaattgtat ggacatgcct ttgtgaancc aggaagtatt ttaagttaaa aatgaaaaag    420
cttttaattg ctttgtgtgt gttttaatgg agccccattt tagaattatt ttttccgtct    480
ccctttacca acaaaaggaa caatgccacc gtgaatggaa tagtttgggg aaagctttgc    540
caaacacaac cctgatttca gagcaggaac atggtttgga tagatcttca gttccgcttg    600
aattattctg ttactgcgct gtcattttca gaagatttcc attcctttgc agatgctgtt    660
gggagttcgg gattatgttc atttcttctg ttttaatggc attcagtact aattttataa    720
gtgcatcttg tgtgaatctc aataaattca gttttgtaat cttttttaaa aaggtcactg    780
aatttatttt aatatttact attgtatttg gtagagtgaa tttcccactg tataataagt    840
atttatttgt aattcacaag tgatagagct atcttaattt gaattattgc tttggtctta    900
atggtggcaa aatgkttaat tttgtctttg gaaaaaatag gctcggcttg attatagacc    960
atttaawatt tctcagcaaa tgaaggtatt tgcattttac aagtgktttg aatgtcacac   1020
caaaatattt tttcacaatc tgggaagc                                      1048

<210> 394
<211> 969
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (845)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (871)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (897)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (899)
<223> n equals a,t,g, or c

<400> 394
aaattgtcta tgaacacagg aaatgagggg ttacctactt ctggttcatt tacactagat     60
gatgatgttt ttgcagaaac tgaagaacca tctagtccta ctggtgtctt agttaacagc    120
aatttaccta ttgctagtat ttcagattat aggttactgt gtgatattaa caagtatgtc    180
tgcaataaga ttagtcttct acctaatgat gaggacagtt tgcccccact tctggttgca    240
tctggagaaa agggatcagt gcctgtagta gaagaacatc catctcatga gcagatcatt    300
ttgcttcttg aaggtgaagg ctttcatcct gttacatttg tcctaaatgc taatctactc    360
gtgaatgtca aattcatatt ttattcctca gacaaatatg gtacttttca accaatggat    420
tgcaggctgg gacagggcag aattattatc tattgttatg tttgccaaat gaagatacta    480
ttcctaagga catcttcaga ctatttatca ccatatataa ggatgctcta aaaggaaaat    540
acatagaaaa cttggacaat attaccttta ctgagagttt tctcagtagc aaggatcacg    600
gaggattcct gtttattaca cctacttttc agaaacttga tgatctctca ttaccaagta    660
atccttttct ttgtggaatt cttatccaga agcttgagat tccctgggca aaggtttttc    720
ctatgcgttt aatgttgaga ttgggtgcag aatataaagc atatcctgct cctctaacaa    780
gcatcagaag gcgaaaacct ctttttggag aaataggaca cactattatg aacttacttg    840
ttganctycg aaattaccag tataccttgc nttaatataa atcaactgtt gaatccntnt    900
ggaaatggga aaaaaccgcc ttaaaattcc ccggaaaagt tcgggatttt tgaaattcta    960
atcccccca                                                            969

<210> 395
<211> 2567
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (74)
<223> n equals a,t,g, or c

<400> 395
ggagaaggcg gcggtnggcg gcgtggacgg cccgcagcgg gacggccgcg gcganggcgg     60
acagccgggc gcancggcgg yacaggggcc cccgccggcg cctcagctca cagagacgct    120
gggcttctac gagagcgacc ggcggcggga gaggcgscgg gccgcacaga gctttcattg    180
ttgaggttcc tcagtgctga actaacaaga gggtacttcc ttgaacataa tgaggccaag    240
tatacagaaa gaagagaaag agtatacact tgtttgcgaa taccaagaga attggaaaag    300
ctgatggttt ttggaatctt tctgtgcctg gatgcgtttt tgtatgtgtt caccctgctt    360
cctttaagag ttttcctggc actattcagg ctcctcactt tgccttgcta tggcttaagg    420
gacagacgtt tgcttcagcc tgcccaggtg tgtgacattt tgaagggtgt cattttggta    480
atctgctatt ttatgatgca ctatgttgac tactccatga tgtaccacct gataaggggg    540
cagtccgtca tcaagctcta catcatctac aacatgctgg aggtagctga tcgtctgttt    600
tcatcttttg gacaagacat attagatgct ctctattgga cagcaacaga gcctaaagaa    660
agaaaaagag cccacattgg ggtgattcct cactttttca tggctgttct ctatgtcttt    720
ttgcatgcaa ttcttataat gsttcaagca acaactctca atgtagcttt taactcacac    780
aacaagtctt tgtctactat catgatgtct aataatyttg ttgaaattaa aggaagtgtt    840
ttcaagaagt ttgaaaagaa caatctcttt caaatgtcaa atagcgatat taaggaacga    900
ttcacaaayt atgtgctytt actgatagtg tgtctaagaa acatggaaca gttttcttgg    960
aatccasatc atctctgggt gttgtttcca gatgtctgta tggtaattgc atcagaaatt   1020
gccgtggata ttgtaaaaca tgcctttatt actaaattca atgacattac tgcagatgtc   1080
tacagtgaat atagagccag tcttgctttt gaccttgtta gcagccgaca gaaaaatgca   1140
tacactgatt acagtgactc tgtagcacgg aggatgggct ttattcctct cccactagct   1200
gttttactca tcagagttgt aacaagctca attaaagtgc aaggaatcct gtcttatgcc   1260
tgtgtcatac tcttctattt tgggttgata tccctgaaag tacttaatag catcgtgctg   1320
ttggggaaat cgtgccagta tgtgaaggaa gccaaaatgg aagagaagct gtcgaatcct   1380
cccgcaacct gcactccagg caagccgtcc agtaaatcac agaacaaatg taaaccctct   1440
caaggccttt ccacagaaga aaacctgtct gcctccatca ccaaacaacc tattcatcaa   1500
aaggaaaata tcataccatt acttgtgaca agcaattctg atcagttttt gacaactcca   1560
gatggtgacg agaaggacat aacgcaggac aattctgaat taaaacacag atcctcaaag   1620
aaagatttgt tagagataga caggttcaca atttgtggaa accgaattga ctgaatctgt   1680
ggcttcatgc gctgaagaag ctgggtcctg gggcaacaag tgctgtgttg ccaggacaaa   1740
tagatgctaa acatggcact taaatattta tttaaaaact taaattatta ttggcaagca   1800
aatcttagta tctttcttcc agtaatatgg cctggctgag ggtcagacca caggacagga   1860
gcgacctccg gccttgactg tctgggaagc ttgatggatt ataaaacttc ctcctgcctg   1920
gccaagcagc agcatcattt ccaggaccca acaaaggcaa catcaaaatc tgttttgctt   1980
tgtcagtctg ggcttccaga atgttgaatt tgcctcaagg cctcttcagt ataaggaaat   2040
acctggaaaa ctgtgaaact tttaccacga cgtaatcttt ccagtctcat actattttca   2100
caaacagttt tcaaacgtta cttcatctgc caaagcatta aaaaaattaa acataagtca   2160
agataaatgt tcttaccacc agaataaccc ttaaagatgt atcttaatta atcagaataa   2220
aaggctacct taaataagac atgatgaata gtagcatttt gtagggttaa aaaaaaaatg   2280
ctaaactagt ttatttatta aaaaaataat taatgaaggc tatgcattac tgggaaaaat   2340
ccttcataat ttttcagttt actctttaaa gcaaaatgtg agctgtatgt catttaattg   2400
gtggataaaa caaatttcct tacaaaaggg cactttttac accaaggaag cagagcagtg   2460
ttaactttaa ggtatactta actgattttg ctttaaaact aattacytcc mtaaattatt   2520
acmgctaaag ggttycgrtg ttggarccgg gcyggaaaat tgtccat                 2567

<210> 396
<211> 1268
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1040)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1213)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1268)
<223> n equals a,t,g, or c

<400> 396
tggaagagta tgttccacgg gagagaagtg aagccagtgg gtccagacct ggaactctca     60
gaggctgaga atggtgtgga ggagaaaaag aaagcctgca ggtcgccaac agcccaatcc    120
cctaccccat ctgtggaggc ggactcccca gaccagaaga aaatcattag cctatggtca    180
aaatccagtt ttgatggtgc ctctttagca agtgataaga acgactgtaa aacagaaagc    240
aaaaatgacc ctaagactga aagaaaaaag tcttcatctt ccagccagta caaggccaat    300
atgcactttc acaagttgkt tcttagtgtc ccaacggagg aaccactgaa gcaaagcttt    360
acctgtgctc tacagaaaga aatactatac caaggaaagc tstttgtatc agaaaactgg    420
atttgttttc attccaaagt ctttggaaaa gacacaaaga tctctattcc agctttctcg    480
gtaaccctaa taaagaaaac caaaactgct cttctagtgc caaacgccct gatcatagca    540
acagtcacag acaggtacat atttgtctcc ttactctcca gagattcaac ttacaaacta    600
ctaaaatctg tgtgtggaca cttagaaaat acaagtgttg gtaacagtcc caatccatct    660
tctgctgaaa acagtttccg agcagaccgc ccttcatctc tgcctctgga tttcaatgat    720
gaattctcag atctggatgg agtggttcaa caaagaaggc aagacatgga aggatatagc    780
agttctggtt ctcaaactcc tgaatctgag aactctcgag atttccatgc gacagaatcc    840
caaacagttc tgaatgtctc caagggagaa gcaaagccaa ctcgggcaga tgcccatgtg    900
aacagagtac ctgaaggaaa agccaagagt ctccctgtac agggtctgtc agaaactgtt    960
ggaatcttac ataaagtcaa gtctcagaaa tgtccgatgc ttcaccatat tcttatattc   1020
tatgcaattg ttgtctgtgn cactaatcat ctcgaccttc tacatgagat acagaattaa   1080
tactctggag gagcagctgg ggttactaac ctccattgtg gacacccata atactggaac   1140
aggcagcacc atctggcctg aggtcacaag tacaattcca atgtgggagg ttctctgttc   1200
agggctttac agntaacata gtgaaattta gaaaaggtta caaaattaac tttacaggag   1260
ttgctttn                                                            1268

<210> 397
<211> 963
<212> DNA
<213> Homo sapiens

<400> 397
gcgggagccc accgtctcca gcttctatgt gaagcgggcg gagctgtggg acacctggaa     60
gttgctcacc tgaaggagca caggagggtt ttccaggcca tgtggctcag cttcctcaag    120
cacaagctgc ccctcagcct ytacaagaag gtgctgctga ttgtgcatga cgccatcctg    180
ccgcagctgg cgcagcccac gctcatgatc gacttcctca cccgcgcctg cgacctcggg    240
ggggccctca gcctcttggc cttgaacggg ctgttcatct tgattcacaa acacaacctg    300
gagtaccctg acttctaccg gaagctctac ggcctcttgg acccctctgt ctttcacgtc    360
aagtaccgcg cccgcttctt ccacctggct gacctcttcc tgtcctcctc ccacctcccc    420
gcctacctgg tggccgcctt cgccaagcgg ctggcccgcc tggccctgac ggctccccct    480
gaggccctgc tcatggtcct gcctttcatc tgtaacctgc tgcgccggca ccctgcctgc    540
cgggtcctcg tgcaccgtcc acacggccct gagttggacg ccgaccccta cgaccctgga    600
gaggaggacc cagcccagag ccgggccttg gagagctccc tgtgggagct tcaggcccty    660
cagcgccact accaccctga ggtgtccaaa gccgccagcg tcatcaacca ggccctgtcc    720
atgcctgagg tcagcatcgc gccactgctg gagctcacgg cctacgagat ctttgagcgg    780
gacctgaaga agaaggggcc cgagccggtg ccactggagt ttatcccagc ccagggcctg    840
ctgggacggc cgggtgaact ctgtgcccag cacttcacgc tcagctgacc ctggcccacc    900
tgtgaataaa tctcagctga ccccagccca cctgtgaata aatgtttttg caggaaaaaa    960
aaa                                                                  963

<210> 398
<211> 833
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (65)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (798)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (803)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (809)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (812)
<223> n equals a,t,g, or c

<400> 398
tcgcagagat tacaccactg caacgagact cgggcccaga cgagatctgc ctgggcgaca     60
cagtnagact ctgtctcaaa ataaataaat aagtaaatag aacctcctga gctaccctgg    120
cttataagga ttcagattac tttaggaaat taggcattag cactaggagg ggggaagatg    180
gctggcaaaa cttctagcta gcaacctatg tctagcacat gggtaactaa ccatagcgag    240
atcctgaaca catatcctct aggtgcaggt ggagggaacg atgtccaata cctgaagcag    300
aatctcacat ggacggaacg tctgtatttc cctctcctgc acgaatcact catcattctt    360
ggagggcttc tctgcattcc tccttttctt ctctcccctc ccctgccttt tgtcttttct    420
aaagagtctg aactccgatt tccatgctct cctgctacat taataagcaa aacctgcttg    480
tgtgtacggt tctttactgg aaacatgact ttttgtttct gtattggttt tactgtcatc    540
cagttttcta gtttaatatc tagcaaaact aaatctgaat gtactcgctt tttccgttaa    600
gtatgccaag cacctcggtt gaaaggcttg actcaaacca gaagtcttgc tggaattcgt    660
ctctgaacac ttgaaaaaca gaaaccctga gccgcaacaa acatgcctct gtgtgtcggg    720
attgcctttg tctctgcttc catgtggctt ttccttttgt agctatgctt agtgacataa    780
tcttccctct tcaagcantc tgngttggnc cnttcccgtt cccccccccg tgc           833

<210> 399
<211> 714
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (188)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (639)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (661)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (690)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (700)
<223> n equals a,t,g, or c

<400> 399
gctgcgagaa gcgacagaag ggtacggctg cgagaagacg acagaagggg gagtcccact     60
ccttcgacct ctgctgcagc ccgtgccgcc gccgcctcct gggaagagag gaagcgggag    120
aggagcccac gtcgcctgtc acccaatatc tccagccgcg cagtcccgta agagtgtaag    180
atgttcgnct gcgccaagct cgcctgcacc ccctctctga tccgagctgg atccagagtt    240
gcatacagac caatttctgc atcagtgtta tctcgaccag aggctagtag gactggagag    300
ggctctacgg tatttaatgg ggcccagaat ggtgtgtctc agctaatcca aagggagttt    360
cagaccagtg caatcagcag agacattgat actgctgcca aatttattgg tgcaggtgct    420
gcaacagtag gagtggctgg ttctggtgct ggtattggaa cagtctttgg cagccttatc    480
attggttatg ccagggtaat catttctatc cctaaataag ttaagagcat gcttgcagta    540
gttgggaaac ttaggctact gaaataatag gctactttgc attaagtgct tactctgtgt    600
cttgcattat atttaaaggg gctttgtatg gcattatcnt cacttaattc tcataacacc    660
ntttgggggt gttatggagg attaacctcn ctggaagggn ccaggaggac acag          714

<210> 400
<211> 471
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (370)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (403)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (413)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (415)
<223> n equals a,t,g, or c

<400> 400
aggcacagat gcatcactac aatgctgggg ttaaacaaag tgctcttctt ggacttaaag     60
accttttgtc tcaataccca tttataattg atgcacacct ttcaaacata ttaagtgaag    120
tgactgctgt gtttacagrt aaagatgcta atgtacgatt agcagcagtt caacttcttc    180
aattcctggc ccccaaaata cgagctgaac aaatttctcc atkttttcct ttggtatctg    240
gtggaggact gagtggtgtg gatgaaaggc tggcatctac tgaaaacctg aaaggattta    300
ttgagataat aattccattg ctaattgaat gctgggttga agctgtacct ccacaactag    360
ctactcctgn tgggaatggt atagaacgag aacctctaca ggntatgcag cangntctta    420
atattatttc ccttctgtgg aaactctcta acacaggatg aaacccataa a             471

<210> 401
<211> 1677
<212> DNA
<213> Homo sapiens

<400> 401
aattcggcag aggaggaacc gagttgcggg agtgcggtct gtgccgttcc gccaggagtt     60
tgccgactgc agacgtcctg cgaaaccgtg gatcaatctt cctgtcctac aactgacaaa    120
ggatccccta aagacccctg gaaggctgga ccatggcaca agaactgcct tcatccatca    180
ccgggagcaa gtgtgggaag agatgcatca acatttggcg tgatgtgggc ctttttgggg    240
tgctaaatga aattgcaaac tcagaagaag aggtgtttga gtgggtgaag acggcatccg    300
gctgggccct ggcactctgt cgatgggcct cttccctcca tgggtccctg ttcccccatc    360
tgtctctcag gagcgagatc tgatcgctga atttgcccaa gtcacaaatt ggtccagctg    420
ctgcttgcgt gtctttgcat ggcaccccca caccaacaag tttgcagtgg ccctgctaga    480
tgactcagtc cgtgtgtata atgccagcag caccatagtc ccctccctga agcaccggct    540
gcagcgaaat gtggcgtctc tggcctggaa gccccttagt gcctctgtct tggctgtggc    600
ctgccagagc tgcattctta tctggaccct ggaccctacc tccttgtcta cccgaccctc    660
ttctggctgt gcccaagtgc tgtctcaccc tgggcataca cctgttacca gcttggcctg    720
ggcccccagt ggggggcggc tgctctcagc ttcacccgtg gatgctgcta tccgggtatg    780
ggatgtctca acagagacct gtgtccccct tccctggttt cgaggaggtg gggtgaccaa    840
cctgctctgg tccccagacg gcagcaaaat cctggctacc actccttcag ctgtctttcg    900
agtctgggag gcccagatgt ggacttgtga gaggtggcct actctatcag ggcgctgtca    960
gactggctgc tggagcccag atggcagccg actgctgttc actgtattgg gagagccact   1020
gatttactcc ctgtcttttc cagaacgttg tggtgaggga aaggggtgcg ttggaggtgc   1080
aaagtcagca acgattgtgg cagatctgtc tgagacaaca atacagacac cagatggtga   1140
ggagaggctt gggggagagg ctcactccat ggtctgggac cccagtgggg aacgtctggc   1200
tgtgcttatg aaaggaaagc caagggtaca ggatggtaaa ccagtcatcc tcctttttcg   1260
cactcgaaac agccctgtgt ttgagctcct tccctgtggc attatccagg gggagccagg   1320
agcccagccc cagctcatca ctttccatcc ttccttcaac aaaggggccc tgctcagtgt   1380
gggctggtcc acaggccgaa ttgcccacat cccgctgtac tttgtcaatg cccagtttcc   1440
acgttttagc ccagtgcttg ggcgggccca ggaaccccct gctgggggtg gaggctctat   1500
tcatgacctg cccctcttta ctgagacatc cccaacctct gccccttggg accctctccc   1560
agggccacca cctgttctgc cccactcccc acattcccac ctctaagaat aaataagttt   1620
tccttttgtt ttccaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa      1677

<210> 402
<211> 2120
<212> DNA
<213> Homo sapiens

<400> 402
tttttttttt tttttttttt ttaggacaat ggtatattta tttacaatcc gaccaaaaaa     60
aggcatacag gcattttttt aattaaaaat aataatgata atgatttaaa aagtcagaaa    120
aattgatgat ctttgaaccc tttatgaggt gtccgtttcc cattccccct aaaaagagaa    180
tctcttaggg aaaaaaaaaa atccaagatt tgaatgaaca aaagactcca atatcgctct    240
ctactgcttg ggttcccttt tctccaactt gatgcttggt ggatgccgct tggcgctgca    300
gtcactgtga ggcaagattg agaaattcac tggtttgatg ggtgaggctg gtagagccac    360
tgggagaatg tggggcagtg aggggaggga catcttccta gcatcaccag catcctgagc    420
tttgtcttgt gttgggagtc ccacaagggc tggtgcaagg gttagcagct gctacttgaa    480
ccctaatccc tgggtggatg tggtctcttg taacttaaga gcaaatgttt gtgatgacat    540
gcacgggtgg gcagaggttg aaaagaacag gggtctacgg aggagccagg ccagccacgt    600
gagacccttc tttctaagtt ggcttcttgt ccattcctgg ggattgggga aagaacgaca    660
gaacttacct tccatcttcc ttctcacaag cagtgttttg ggtgtcccca aaaggaggag    720
gcaagaactc aggtgtgggg tggaggggat ggggctggct aaagaagtga gtatgacccc    780
agaggccaga gagggcaggg agagaatgcc tggccactta caggagggga tctgtaatct    840
ctgggcctcc ctgttctgcc tgaagttggc agggcccact gctagcacac cttggagagc    900
ggtacctcct gaggaaaggg ctggggagtg atcctgaggg gtaaggaccc tagcggcctt    960
ggccatccct tcccagacac agacaagtgg atgcttggct tgggaaatac ttggccccag   1020
gtccagggtt tcttggcaca aaaacagttc actgcaagtc tcttctcttc ttccttgtgg   1080
tccagcaaac tccggctgct ctgaacaggg gcaattcctg ctgtctgggg aacctggccc   1140
ccagtacttc caggggattt tcttgtagca actaagactt gggtttgctc ctggtgaaaa   1200
gatgaccccg aggccctggc tggaaaccct gccttgggca gccctggagg aggctgggga   1260
gaagagggaa agagaggtct ggcagaggct ggctggcact gagggtgctg tccgagctgg   1320
agctgtgctt tgtcgtggcc tcagtggtga ggatgggcag ggagaggctc ggaaacctca   1380
ctgaagctct ggcgtgtcct cttccagtta gtcatagggt ggccaacagc cctgaggaac   1440
tgaggtggag acagtgacca aaacccttat ctcggtggat ttatccatcc tggatccatt   1500
tgttaaaaca aagaaggaaa aaaaaatcca aaccagaaat acacctgaat aaacaggtca   1560
gagagttcct gttggaggga actttcttag cactgaagaa aaagcaaccc acaaaaaaac   1620
tcatccccca cagaactgga ataagatgac gaaaaacgca agattatcta caggccctcc   1680
cgccccccac gcagctgaga aggtactggt tgtgctttca ttttctgcgt ttcctcgccc   1740
ccctcactcc tccgtccaga ggcagcctta cttctccaaa gaggacgctc tgagtctgcg   1800
ttcccctggc agcaagtcct gaggcaagat ttggggacaa gcagctcctg tgggaagtgg   1860
ctccaggaag ccccaggaga gacgcgggga gtgagcccag cgggaaggac aggcagcgag   1920
gaccgctcca aaggtggtgc ctcagcagca attcttttct gctcggctgt cctcgagcag   1980
ccccgcccgc cccgggccct ccggctcccc agacggcact tagcatcccg ctctcttcct   2040
tcccctctgt gccaggccgg tcgcccctcc agaccctcgc ggtctctact tgcccgtcga   2100
ccaccggacg cgtgggtcga                                               2120

<210> 403
<211> 654
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (578)
<223> n equals a,t,g, or c

<400> 403
ggcacgagct ggcactgcgg ccgctccgca gcagagaagc cgggagcggg cgaggcggcg     60
gcggcascag cgatggcagg aatagagttg gagcggtgcc agcagcaggc gaacgaggtg    120
acggaaatta tgcgtaacaa cttcggcaag gtcctggagc gtggtgtgaa gctggccgaa    180
ctgcagcagc gttcagacca actcctggat atgagctcaa ccttcaacaa gactacacag    240
aacctggccc agaagaagtg ctgggagaac atccgttacc ggatctgcgt ggggctggtg    300
gtggttggtg tcctgctcat catcctgatt gtgctgctgg tcgtctttct ccctcagagc    360
agtgacagca gtagtgcccc acggacccag gatgcaggca ttgcctcagg gcctgggaac    420
tgacccagct ggtcctgaag gagaagccaa atggctgcac tggccgattc tggtctccag    480
aggaccttgg tgtttgctct cccttgaccc accccagtga gtgccaaagg gcagccccaa    540
catgtgcacc cctgcatttc ctgtcatgcc acagactngc ccttgagggc agcctgctgt    600
actggccatg ctggccagcc ccacctggag ctcagtaaaa actgctgttt gatt          654

<210> 404
<211> 1573
<212> DNA
<213> Homo sapiens

<400> 404
tcgagttttt tttttttttt ttttgtcctt ttagtaagaa aaactttatc aaaaatttaa     60
atatataaaa taaggccaga gstgcactgg aggccacttc ccagtggtgc actgctgcgc    120
tgggtgtccc tatgcagcta gatacatgtt aactgcatag agtaccataa aggagcccac    180
tggtgagctt cactgtcacc tggccctgct ggctggggct tccattgtct actgggtctg    240
tccacacccc agattgcctt gtggtccttt cccctggcca agaagataac agttttttaa    300
aaatcccctt ctgatatgga tgtgagcaag cagtggggtt cagtttggga ccaagyagtg    360
ccatttacaa agagcatggg aagcacctcc ttaggagggg agcagggcca tctccacgtt    420
gtcaggggcc gcgccgttgc ctgccagacc ctgggcccac ttgtgcaggc ggctgtagag    480
tgggaggccc tggttctcac ggtacaagta gacgccggtg atggcattcc actgtggccg    540
tggctgcgtg ccttccactg ggaagttggc aatcagttcc tcatcatcct tgttgagcgc    600
cacaaagcca aagaagcggc gcacattgtt ggcagcgagc acccgagagt gcacctcggc    660
cgtgcgctgg aacagctggt cctcattggc gcggtactgc gcccagtagg cctcctggcg    720
gtagctgagt ggtgagcagt aatgcttgag gcacttggtc aggaacacca ggatggccac    780
cacgccgatg agcagccatc caaagagctg ggactcatac ctgactgcgg ctgacctcct    840
cccggaagtc tgacaggttg tcagggttct ccttgcaggg gaacctggcc aggatttcag    900
tggcgtgggc tgatgggaag tgctcttccc tggccgtgag tgaggaaggg tccacgaact    960
cactgagagc acagacataa gcctcaccac gcagcaggga gatgacagac caggtgacag   1020
gggccacagc cgcacgtccc aggatggagc ttagaaggag gaaggttggg gccggcsgar   1080
cagttcttgg tcctccggtg ctggcactcg gccacgaggt tccaggtgtg gttgttgagg   1140
atgatgccaa tgatgaagag caccagggcg ggcacgccga tggccgccag cccktacagg   1200
tarttccggg ccggcgarcm ggggcagtgg aaggccacca cagagaacag ctcctggctg   1260
cccaccgtgc ccagtgccac caggccgttg aaaatcatca catccttgct cttgaagaaa   1320
agtgacagga agcggaagtt ctctgcgatc arggctgcca tggcgatakt cktggcgggg   1380
tggattgcag gagaggaggc aggaggagac gggattgatg gttgctggtg gtactaggaa   1440
ggggcacagg ctgggaggcg ctggacggca gggtgtggtt gtgctatttt atccccagct   1500
gtggttggcc tggtgtttcc ttgccgtgtc catccacggg tgtcccgaag aacctcgtct   1560
tccgcagccg tga                                                      1573

<210> 405
<211> 813
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<400> 405
gaatcccccc gggctncaag gaatttcggc aacgagggac tacagtgagg acgaaatcta     60
ccgcttcaac agccccctgg acaagaccaa cagccttatc tggaccacga ggaccacaag    120
gaccaccaaa gactcagcct ttcacatcat gtcccacgag agcccaggca tcgagtggct    180
ctgtctggag aatgccccat gctatgacaa tgttccccaa ggcatctttg cccctgaatt    240
cttcttcaag gtgttggtga gcaatagagg agtggacacg agcacctact gcaactacca    300
gctcaccttc ctgctgcaca tccacgggct gccactcagt cccaagcggg cccttttcat    360
catcatggtg tcagctagcg tgtttgtggg cctggtgatc ttctacatcg ccttctgcct    420
cctgtggccc ctcgtggtga agggctgcac gatgatccgg tggaagataa acaacctcat    480
tgcctcagaa tcctactaca cctacgcctc catttccgga atctcgagca tgccatctct    540
gagacattcc aggatgggct ccatgttcag ctccaggatg acagaggaca gggctgaacc    600
caaggaagcc gtggagagac agttgatgac ctgagtgtcc cacctgcccc agcccccagt    660
tactgtcacg cctctcttat gaggcccatc ttgaagatgc aacctgtcac ccagcccagg    720
cctctctttc tgttttgctt gatgtttact tctcgttcag actcaaataa agcctttttt    780
caggaccaaa aaaaaaaaaa aaaaaaactc gag                                 813

<210> 406
<211> 1348
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1251)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1306)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1313)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1316)
<223> n equals a,t,g, or c

<400> 406
ggcctgttca acccacccat gccccaggaa caacggcagc tgcccacaat accacccgca     60
cagctgcacc tgcctccacg gttcctgggc ccacccttgc acctcagcca tcgtcagtca    120
agactggaat ttatcaggtt ctaaacggaa gcagactctg tataaaagca gagatgggga    180
tacagctgat tgttcaagac aaggagtcgg ttttttcacc tcggagatac ttcaacatcg    240
accccaacgc aacgcaagcc tctgggaact gtggcacccg aaaatccaac cttctgttga    300
attttcaggg cggatttgtg aatctcacat ttaccaagga tgaagaatca tattatatca    360
gtgaagtggg agcctatttg accgtctcag atccagagac agtttaccaa ggaatcaaac    420
atgcggtggt gatgttccag acagcagtcg ggcattcctt caagtgcgtg agtgaacaga    480
gcctccagtt gtcagcccac ctgcaggtga aaacaaccga tgtccaactt caagcctttg    540
attttgaaga tgaccacttt ggaaatgtgg atgagtgctc gtctgactac acaattgtgc    600
ttcctgtgat tggggccatc gtggttggtc tctgccttat gggtatgggt gtctataaaa    660
tccgcctaag gtgtcaatca tctggatacc agagaatcta attgttgccc ggggggaatg    720
aaaataatgg aatttagaga actctttcat cccttccagg atggatgttg ggaaattccc    780
tcagagtgtg ggtccttcaa acaatgtaaa ccaccatctt ctattcaaat gaagtgagtc    840
atgtgtgatt taagttcagg cagcacatca atttctaaat actttttgtt tattttatga    900
aagatatagt gagctgttta ttttctagtt tcctttagaa tattttagcc actcaaagtc    960
aacatttgag atatgttgaa ttaacataat atatgtaaag tagaataagc cttcaaatta   1020
taaaccaagg gtcaattgta actaatacta ctgtgtgtgc attgaagatt ttattttacc   1080
cttgatctta acaaagcctt tgctttttat caaatggact ttcagtgctt ttactatctg   1140
tgttttatgg tttcatgtaa catacatatt cctggtgtag cacttaactc cttttccact   1200
ttaaaattgg tttttggttt tttggagacg ggagtttcac ctccttgtca ncccaaggct   1260
gggaagtacc agtgggcacc gatcctcggg ccttaagggc aacctncggc ctnccngggt   1320
tccaagtgga atctcccggc ttcagctt                                      1348

<210> 407
<211> 1596
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (130)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1567)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1569)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1592)
<223> n equals a,t,g, or c

<400> 407
agcctggggc cagactggtg ctaacactgc aaactttgtc cagagctctc tccaacctga     60
aggcttgctg ggggtgcaat gtcaccttca cacatgctgg gccctttcag aaaagtgcca    120
gatcgtgtan tggtgctatt tttcatgctc tggtacaatg tgtagcacca cgggggtctc    180
agctttacca aaatcaaaat tccatttgtc agctaagtgc agaggcattt gttttttgct    240
ctcctyccac agaattgtcg gccatttatt tgcaggcytt ttgcgggatt tcttggctat    300
ttatttgcag gccttttttc ccagccccaa attcttgggt tggctctgtc tgcttaaaga    360
gcctgtcttc acaaagctgc actcgggtgc ctctgtgcgc tgtcttagat cctactgccg    420
gcccttcagg actccgagcc aggaaagaac tctccaacct ctggctcgag actctacttt    480
ttttctcatt cttttcctta ctctcctcct ccttctactt ccgactaatt ccatctcttt    540
tttttttttg ttcctctcct tttcctattc ctccttccca ccatctctga gttgttgact    600
ttctcctata atccttctct attccctttc tctttttgtc cacctctcct ttagtctctg    660
tttctctgcc cttcttattc ctcttctgtc ctttctcctc tcctcaaatc tctgatcatc    720
ttctcccgta catccctgta ttgatttttc tgtcctctaa agggctcatg gctgattcag    780
acagcaagtc catgcactgg actaatgaca caaatacttt aggtcgccgt ttcacctact    840
cagcccagaa agtaaagctg agcgtgaggc cctgacctgg agcctgctcc agcccgcctc    900
ccggagccag cctgcaccgt tgccctggca gcgatgatgc atgtgctgtg ggccctgccg    960
gcgcctgagt gcctctgcct gaacactgct cctaagcgag cccactccca gcactaccgc   1020
atggctctga ggacattttc tttcaataaa ggcagactct ggccccaatt attctgatag   1080
caaacctctt cctcctcatt gaagccatgc catcaccttg gtttggagag agacattttt   1140
ttcccattca taagctttct ttttcccatt tttatgtgaa gccccctctg cttttcagct   1200
ggtgattgct ckggtgagac tgaatggayt tgctggtgaa atgaaatctc ttctttcctg   1260
tcttggtcct gcctaaattc ctacaaatat atttaagcca aggactcagg ctaattccta   1320
agttgatcac attartttgt tactcctaga gggaaaaaga tcaattccct tgaagcatgt   1380
ggagtacctc ctgtgaacag ctgacttgcc aggggactcc ctacagaatt ctgtgatata   1440
cattttactt ctgtgtatgt atggtatata tggtatgtat accatgttac acacgttaca   1500
tgagtatgaa tgactgtggt tgggaaaccc acacacacat tcaagtccgt aaataatcct   1560
tccccangna accgtgcttt gggaatcatt tntggt                             1596

<210> 408
<211> 1564
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<400> 408
gcagtanccg acagtaccgt ccgaattccc ggtcgaccca cgcgtccggg ttttatgtgt     60
tagattcctc tgaatataac tttcacattt tgtcctcttt tgtgctaata gaacattcta    120
gtatgccagt agaaaaaaat atcactttag aaaggccttc taatgtaaat ctcacatgcc    180
agttcmcaac atctggggat ttgaatgcag taaatgtgac ttggaaaaaa ratggtgaac    240
aacttgagaa taattatctt gtcagtgcaa caggaagcac cttgtatacc caatacaggt    300
tcaccatcat taatagcaaa caaatgggaa gttattcttg tttctttcga gaggaaaagg    360
aacaaagggg aacatttaat ttcaaagtcc ctgaacttca tgggaaaaac aagccattga    420
tctcttacgt aggggattct actgtcttga catgtaaatg tcaaaattgt tttcctttaa    480
attggacctg gtacagtagt aatgggagtg taaaggttcc tgttggtgtt caaatgaata    540
aatatgtgat caatggaaca tatgctaacg aaacaaagct gaagataaca caacttttgg    600
aggaagatgg ggaatcttac tggtgccgtg cactattcca attaggcgag agtgaagaac    660
acattgagct tgtggtgctg agctatttgg tgcccctcaa accatttctt gtaatagtgg    720
ctgaggtgat tcttttagtg gccaccattc tgctttgtga aaagtacaca caaaagaaaa    780
agaagcactc agatgagggg aaagaatttg agcagattga acagctgaaa tcagatgata    840
gcaatggtat agaaaataat gtccccaggc atagaaaaaa tgagtctctg ggccagtgaa    900
tacaaaacat catgtcgaga atcattggaa gatatacaga gttcgtattt cagctttgtt    960
tatccttcct gttaagagcc tctgagtttt tagttttaaa aggatgaaaa gcttatgcaa   1020
catgctcagc aggagcttca tcaacgatat atgtcagatc taaaggtata ttttcattct   1080
gtaattatgt tacataaaag caatgtaaat cagaataaat atgttagacc agaataaaat   1140
taattatatt ctggtcttca aaggacacac agaacagata tcagcagaat cacttaatac   1200
ttcatagaac aaaaatcact caaaacctgt ttataaccaa agaattcatg aaaaagaaag   1260
cctttgccat ttgtcttaga aagttatttt ttwaaaaaaa atcatactta ctattagtat   1320
ctatggaagt atatgtaaca atttttatgt aaaggtcatc tttctgtgat agtgaaaaaa   1380
tatgtcttta ctaagttgaa atgaatactt tctgcctttg ctaatgatag ttattctaca   1440
atctccacaa gaaaaatata ccttttatcc ggaaatattg gtttaaggca aataaataaa   1500
actgtgcttg ctctaaagct ctgcactaca aaagcaaaaa aaaaaaaaaa aaaaaaaaaa   1560
aaaa                                                                1564

<210> 409
<211> 929
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<400> 409
ttaagnttgg ccccttngng ggatcttttg gagcggcccc cctttttttt tttttttttt     60
tcattaaaaa atagtgctct ttattataaa ttactgaaat gtttcttttc tgaatataaa    120
tataaatatg tgcaaagttt gacttggatt gggattttgt tgagttcttc aagcatctcc    180
taatagcctc aagggcctga gtagggggga ggagagagga ctggaggtgg aatctttata    240
aaagacagag tgattgaggc agattgtaaa cattattaaa aaacaagaaa caaacaaaaa    300
aatagagaaa aaaaccaccc caacacacaa ctgccctgtc cagcccaata cctgacacag    360
aatactttgt gtttgtttag ttgccccccc ccacaaaaac aaaaacaaaa acaaaaacaa    420
aaaactgttc caggtaattc catcgctgct acattcctgt aaattgtcac tgatcagtgc    480
tatggcagag cgggagcacc cggggtggca gcagtccagc ctctccaatg acctccagcc    540
tcccccaccc aggcaggagg gagggctgtg cagggctcgg ggcagtggga cctggtggct    600
ctgctctgac cacgaggcgc ctgactggcc aatacttact gggctgacat tcccagtgct    660
cagctgggag gcatgggttt ccgccccccc tccccacttc cctggctgtg ggctggcttg    720
gtgccctcca gtgagtccct cagcctctcc acccatccag gctgagtatg tggctttcct    780
atgctgggtc cctctccatg ggacagggag catttaaggc gaatctctta gccagacata    840
gtcaggaggc acagagtaga atcccctgtc ttctctacca ggagcctgag gtgaaagatg    900
tcccgtctcc tccatcctcc cgctccatc                                      929

<210> 410
<211> 2318
<212> DNA
<213> Homo sapiens

<400> 410
gccagggtgg cctttagcac agtatcagta ccatttattt gtctgccgct tttaaaaaat     60
acccattggc tatgcacttg aaaacaattt gagaagtttt tttgaagttt ttctcactaa    120
aatatggggc aattgttagc cttacatgtt gtgtagactt actttaagtt tgcacccttg    180
aaatgtgtca tatcaatttc tggattcata atagcaagat tagcaaagga taaatgccga    240
aggtcacttc attctggaca cagttggatc aatactgatt aagtagaaaa tccaagcttt    300
gcttgagaac ttttgtaacg tggagagtaa aaagtatcgg ttttattctt tgctgatgtc    360
ctttctgctt gaaataacag tcaccataca gctaaaggag aggagtttct ttccttctaa    420
gtaggcagaa atggtatcat tatgttgccg ctctccaatc tcccagagct cgctctctag    480
agaatcacct tctttataaa gcgtcagtca tgcttccagc aagaggcagc atcagtcatg    540
gctttataac agcttcatgg tgcctcaaag actgttgagg ttaatgagag cctagattag    600
acagtttggc tgtccttccc taaaacttgt tttctcctat tcactactcc ccaccgcact    660
taaaatctat gagtttttac tttttactgg gaatggaaag tgtggtgaag atcattcaac    720
acttatgttg tcatttctcc cattttctga attttttttt aaatttcccc ccttttaaaa    780
ttgttcgaaa gcccacagtt atggaaagaa ttactgtcta gatggtctgc agaacgtgtt    840
tggggtgagt gggagtgagg ggcaatgtta ctttttctcc ctgtagtttg gagtccatta    900
tgagctgctg ctttttcttc tcatcttgtc atcttctggg gatgtttgaa ggctgagttc    960
caacagaatt cacaaaggga ataaaacagg attgagattt tgaggtgtgc acaaggtggt   1020
aagataaagg gcatatgagc ttcaaaacta atgctgttgc atacatgaag ccttttgttt   1080
tttgaggagc tatttttgtt attcttgtaa cgctccacct tacatgccac gtctgtgtga   1140
gtcaacaggg atcaggtttg gtcaccacac atgtctgaag ctgggcagcg tctgctctgt   1200
gttctgtgtg gaatggagaa aaaaacgcct gccctgctgc cttccatgtt cataggccca   1260
gcccaagaga gtgacacaca gtgctggccc tgagacattt ccacaaagtg gtcaactctg   1320
ccttgcatcc taaaactttt tgggcatcta ttttgaaaac tataggagcc tttggaaggc   1380
ctcttatgtt tggaggggaa gggtgttgag attgtcacca tccttcaagc tgagactcct   1440
ggtgagcctt tgccaccatg aaaaccacat agctgaccag ggctgtgctt gaggtacaga   1500
ggacacacat ygtagacagg cctgtgtcat gtttccttac agtcgttttt tacagagaaa   1560
aggggcattg ttttttcact gctttctcaa cagttcctgt gaataaatga aacatttcgg   1620
agctccctga gagcaagagc cttcacttct tcttgcggtg ccgggaccat gtgttggtga   1680
agctggtgct gtgggggcca ctcactcgaa tgacacctgg aggcctgttc ctcccttacc   1740
actcccttcc ccagcccgac ttcttggcct cctgcccaac cagacacctc aaactctgtc   1800
agtgccctgg cattctggca gagaatcctc accagttctc accaaccttc cccccaggca   1860
agggcagctg ccagcatggt gctctgccag gacaggtttc cctgaaggaa gctgctcaca   1920
ctgagatgag cctctcaggg caggacctct tcccaagccc tgcacaccca cccctgcagc   1980
ccttttggct ccccttttcc ctgtgcctca gcactccttt cctggttgca gataacgaac   2040
taaggttgcc taaagggcag atctgccctc tccatgtctt cgtcctggca aacagggtcg   2100
tcttaaaatt atgcgctaat tctgtatggg agcactcaaa aggcattact tagagattga   2160
aatttcaaac tatctctagt ttttcaatgg aaatatatca gctagggaaa aaccatcaag   2220
ctcattatta ttttttgatc ttcagttgta tttttgtgaa tattttaata catctttttc   2280
aatttctgaa aaaaaaaaaa aaaaaaaaaa aaaaaatt                           2318

<210> 411
<211> 619
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (72)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (102)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (121)
<223> n equals a,t,g, or c

<400> 411
ccnaaaagac tcaaatatgg tcctgagtaa cagcaaccag ctgctgctga attcgttgac     60
tcaggcagac gntggcacct acacttgccg ggccatcttg cntcgaatcg gagtggctga    120
ncgggaggtg ccgctctatg tgaacgggcc ccccatcatc tccagtgagg cagtgcagta    180
tgctgtgagg ggtgacggtg gcaaggtgga gtgtttcatt gggagcacac cacccccaga    240
ccgcatagca tgggcctgga aggagaactt cttggaggtg gggaccctgg aacgctatac    300
agtggagagg accaactcag gcagtggggt gctatccacg ctcaccatca acaatgtcat    360
ggaggccgac tttcagactc actacaactg caccgcctgg aacagcttcg ggccaggcac    420
agccatcatc cagctggaag agcgagaggt gttacctgtg ggcatcatag ctggggccac    480
catcggcgcg agcatcctgc tcatcttctt cttcatcgcc ttggtattct tcctctaccg    540
gcgccgcaaa ggcagtcgca aagacgtgac cctgaggaag ctggatatca aggtggagac    600
agtgaaccga gagccactt                                                 619

<210> 412
<211> 1209
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1203)
<223> n equals a,t,g, or c

<400> 412
cttcgccgtc atccgcttcg aaagcatcat ccacgagttc gacccgtggt ttaactatag     60
atcaacacat catcttgcat ctcatgggtt ctatgaattt ttaaattggt ttgatgaaag    120
agcatggtat ccactaggaa gaatagtagg tggtactgtt tacccagggt tgatgataac    180
cgctggcctt attcattgga ttttaaatac attgaacata actgttcaca taagagacgt    240
atgtgtgttc cttgcaccaa cttttagcgg ccttacatct atatctactt tcctgcttac    300
aagagaactt tggaaccaag gagcaggact tttagctgct tgttttattg ctattgtacc    360
aggctacata tctcggtcag tagctggatc ctttgataat gaaggcattg ctatttttgc    420
acttcagttc acatactatt tatgggtaaa atctgtaaaa actgggtcag ttttttggac    480
aatgtgctgc tgcttatcct atttctatat ggtctctgct tggggtggtt atgtatttat    540
catcaatctt attccactgc atgtatttgt gttgttactg atgcagagat acagcaaaag    600
agtctacata gcatatagca ctttctacat tgtgggttta atattatcaa tgcagatacc    660
ttttgtggga ttccagccaa tcagaacaag tgaacacatg gcagctgcag gtgtctttgc    720
attgctgcaa gcttatgctt tcttgcagta tctgagagac cgattaacaa aacaagagtt    780
ccagaccctt ttctttttgg gtgtatcact agctgcaggt gctgtgttcc ttagtgtcat    840
ctatttgact tatacaggtt acattgcacc atggagtggc aggttttatt cattgtggga    900
tactgggtat gcaaaaatac acattccaat tattgcatca gtgtctgagc atcaacctac    960
gacttgggtg tctttcttct ttgatctaca tattcttgta tgtaccttcc cagcaggcct   1020
ttggttctgc atcaaaaata tcaacgatga aagartattt ggtaagagag gtttttaatg   1080
actactttga tatggaatag ttatttttct ttttgagatt atttacttta aatttttgtt   1140
tttctatgtt tgactctata tattcaagat aaattttctc ctttattttg cataggtgct   1200
tanccaaga                                                           1209

<210> 413
<211> 2294
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2287)
<223> n equals a,t,g, or c

<400> 413
ctgcactcag ccctgatcta ctttctggga acctttctgc tatccatatt gatcgcctgg     60
actgtgcagt atttccagtc tgtctcagca agcgatcccc ctccaagacc atcccttgcc    120
ttagagctga tgaagaaagc agcttccaag ggattgcatc aggcagtcaa tggcctggga    180
tggtattacc acaaattcaa gaaaaattac gccaaagcag caaagtactg gttaaaagca    240
gaagaaatgg ggaacccaga tgcgtcatac aatcttggag tcctgcattt ggatggcatc    300
ttccctggag ttcctggaag gaatcaaact ttagctggtg aatatttcca taaggctgcg    360
caaggtggac acatggaagg gaccttgtgg tgttctctct actatatcac aggcaacctg    420
gagacattcc ctagagatcc tgagaaagct gttgtatggg caaaacatgt agctgagaaa    480
aatggctact tgggccatgt catccgcaaa ggcctcaatg cctacctgga aggttcatgg    540
catgaagctt tgctgtatta tgttttagca gcagaaactg gaattgaagt gtcacagaca    600
aatttagcac acatctgtga ggagaggcca gacctggcca ggagatactt gggtgttaac    660
tgtgtttgga gatactataa tttctctgtt tttcaaatcg atgctccttc ctttgcatat    720
ttgaagatgg gagaccttta ctactatggc caccaaaacc agtcacaaga cctggagttg    780
tctgtgcaga tgtacgccca agccgccctg gatggagact cccagggatt ttttaacctg    840
gccctgctaa tcgaggaagg tacgataatc ccacaccata tcttggattt cttggaaatt    900
gactcaactc tccattctaa taacatctcc attctccagg aactgtacga aaggtgctgg    960
agccacagta acgaggagtc cttcagcccc tgctccttgg cctggcttta cctgcacttg   1020
cggcttctct ggggtgctat cctgcactca gccctgatct actttctggg aacctttctg   1080
ctatccatat tgatcgcctg gactgtgcag tatttccagt ctgtctcagc aagcgatccc   1140
cctccaagac catcccaggc ctccccagac actgccacgt ccactgcaag tccagctgtg   1200
actccagctg cagatgcctc tgaccaagac cagcccacag taactaataa cccggagcca   1260
cgtgggtgaa ctgtgcactc cagttctctc cagatgagag agaatctttt caacagctgg   1320
tattgggaag ctggggccag ggcatgatcc tgataaacac cttaaatgtc ttgtcaactg   1380
gatgcaaatt ttgcaattgg tgtcattttt tttaaagtca aattacaagg aagtacccag   1440
atcaggcagt ggtaatacca aaggtcatca aacacataca aggaacatct tgatcatagg   1500
gcatgtgggg aagtttactg ggccatcaca gacttttgtt ctagtgattg tatgtattag   1560
gagtcatagc atgccctacg gcagatctgg attcttatac actaagatgt gtcttaagaa   1620
tcacagtgcg tgcttcatcc ctttattgaa gaacagaaaa ttatgactac tctacaaggt   1680
ggataatatt ttggtacctg tgcttgccac agccctgttc ctcaaagctg aattgataga   1740
tttctctttg acttccaaga cctagcagtt ataaggcacc ttgaaataaa ttgtttgtgc   1800
ctggaaatgc agggagggca atagctttgt aaattggttt acatttttct ccttgaattt   1860
ttctagggtc ctagtgcttc cgaatcattt aatggcattg tcggatatct tttacatttc   1920
aattgcaatc catgaaatta catttagaag attcttagta cttaactgta gtcttctcca   1980
tgaattacac gttagaatag actggcagca actgaatatg cagcaagtaa gcctctagct   2040
tatagtttca tccctacccc tcatgcctgc gtgagtctgt acagggatat gtgtgtgtgt   2100
gtgtgtgtgt gtgtgttaga gaggaagagg aagagcagaa tgtctgtata ctacatgctg   2160
ctaaggtagt gaataaatca gtaatgcaat attgtgggtc caaactactc tttgcactac   2220
tttatttaca gtagtaaata aaattatttt tatacaattg aaaaaaaaaa aaaaactcga   2280
ggggggnccc gaaa                                                     2294

<210> 414
<211> 817
<212> DNA
<213> Homo sapiens

<400> 414
gctgacggaa gcggcggcag cgggcagcgg ctctcgggct gcaggctggg cagggtcccc     60
tcccacgctc ctgccgctgt ctcccacgtc ccccaggtgc gcggccacca tggcgtccag    120
cgacgaggac ggcaccaacg gcggcgcctc ggaggccggc gaggaccggg aggctcccgg    180
caagcggagg cgcctggggt tcttggccac cgcctggctc accttctacg acatcgccat    240
gaccgcgggg tggttggttc tagctattgc catggtacgt ttttatatgg aaaaaggaac    300
acacagaggt ttatataaaa gtattcagaa gacacttaaa tttttccaga catttgcctt    360
gcttgagata gttcactgtt taattggaat tgtacctact tctgtgaatt gtgaactggg    420
gtccaagtga gttcaagaat ctttatggtg tggctcatta ctcacagtat aaaaccaatc    480
cagaatgaag agagtgtggt gctttttctg gtcgcgtgga ctgtgacaga gatcactcgc    540
tattccttct acacattcag ccttcttgac cacttgccat acttcattaa atgggccagg    600
tggcgatatc ttgcagttta gtttctcctt gtcctgtgca tgcttatttt gtgtgctaac    660
gccagagaat taaaattcgt gtttcagccc cacgatgcca gaatgctgtt ataggaggta    720
taactggtat aactaataat tatacaagtt atgattkgta ttctaaaagc ttaatgatga    780
gagaggaatc gtattaataa atattttgag tgaaatc                             817

<210> 415
<211> 843
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (798)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (799)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (832)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (840)
<223> n equals a,t,g, or c

<400> 415
gccaatctgg gctactttca gctgaaagcc aacccaggag cttggatcct cagacttagg     60
aagggacgct ctgaagatat ttatagaatt tacagccacg atggcactga ttctccccct    120
gatgctgatg aggtggttat cgtcctcaac aacttcaaaa gcaaaattat taaagtgaag    180
gttcagaaga aggcagatat ggtgaacgaa gacttgctga gtgatggaac gagtgagaat    240
gaatctggat tttgggattc cttcaaatgg ggctttacag gacagaagac tgaggaagtg    300
aagcaagata aagatgacat aattaatatt ttctccgttg catctggtca tctctacgaa    360
agatttcttc gcataatgat gctatccgtg ctgaagaata ccaagactyc tgtgaaattc    420
tggttcttga agaattactt gtcccccaca tttaaggagt ttatacctta catggcaaat    480
gaatacaatt tccagtatga gcttgttcag tacaaatggc cccggtggct tcatcaacaa    540
actgaaaaac agcgtatcat ctggggttac aagatcctct tcctggatgt acttttccca    600
ctagtkgttg acaagttcct gtttgtggat gctgatcaga ttgtacgaac agatctgaaa    660
gagttaagag atttcaattt ggatggtgct ccttatggtt acactccttt ctgtgacagc    720
cgagagaaat ggacggtaca ggtctggaag tcagggactg gggccatcat ttagccgggc    780
gaagtatcta acagggcnna tatgtagggg tcggagaagt taggaaaaaa cnccggtgan    840
aac                                                                  843

<210> 416
<211> 749
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (706)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (735)
<223> n equals a,t,g, or c

<400> 416
aagggacaga gggcagtgat cagcaatgga aggatcattg ggccactgga ggatagtgag     60
ctctttaatc aagacgattt ccacctcctc gaaaatatca tcttaaaaac ctcaggacag    120
aaaataaaat ctcatattca acagcttcgg gttagaagaa agatgtggca agcgacttgg    180
taatgaaggt ggatgctctt ctgtcagcgc aaccaaaagg agatccaaga atcgagtacc    240
agttttttga agacagacac agtgcaatca aactgaggcc gaaggaaggg gagacatact    300
ttgatgttgt ggctgtcgtt gaccctgtca ccagagaagc acagagactt gctcctttgc    360
tcttggtttt ggctcagctg ataaacatga atctgagagt atttatgaac tgccaatcca    420
aactttctga catgccttta aaaagctttt accgttatgt cttagaacca gagatttctt    480
tcacttcaga caatagtttt gctaagggtc caatcgcaaa atttttggat atgcctcagt    540
ctycactgtt cactctgaat ttgaacacac ctgagagctg gatggtagaa tctgtcagaa    600
caccatatga tcttgataat atttatttag aaagargtgg acagtgtnat ggctgctgar    660
ttatgagctg ggaatacctn gttactggaa rggycattgc tacganattc accacaggcc    720
agcctccacg gggantaccg tttacctta                                      749

<210> 417
<211> 684
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (567)
<223> n equals a,t,g, or c

<400> 417
gcggccgcat tcctgcaggg gatgactgtg aatggcttca tcaacacagt catcacctcc     60
ctggagcgcc gctatgacct gcacagctac cagagcgggc tcatcgccag ctcctacgac    120
attgccgcct gcctctgcct caccttcgtc agctacttcg ggggctcagg gcacaagccg    180
cgctggctgg gctggggcgt gctgcttatg ggcacggggt cgctggtgtt cgcgctgccc    240
cacttcacgg ctggccgcta tgaggtggag ttggacgcgg gtgtcaggac gtgccctgcc    300
aaccccggcg cggtgtgtgc ggacagcacc tcgggcctgt cccgctacca gctggtcttc    360
atgctgggcc agttcctgca tggcgtgggt gccacacccc tctacacgct gggcgtcacc    420
tacctggatg agaacgtcaa gtccagctgc tcgcccgtct acattgccat cttctacaca    480
gcggccatcc tgggcccagc tgccggctac ctgaattggg aggtgccctg ctgaatatct    540
acacggaaat gggccgacgg acggagntga ccaccgagaa gcccactgtg ggtcggcgcc    600
tggtgggtcg gcttcctggg ctctggggcc gctgctttct tcaccgccgt tcccatcctt    660
ggttaacctt cggcagttgc cagg                                           684

<210> 418
<211> 505
<212> DNA
<213> Homo sapiens

<400> 418
gaacatgctc aagttgggag ccagtgtgaa catgtacatg ttccatggag gtaccaactt     60
tggatattgg aatggtgccg ataagaaggg acgcttcctt ccgattacta ccagctatga    120
ctatgatgca cctatatctg aagcagggga ccccacacct aagctttttg ctcttcgaga    180
tgtcatcagc aagttccagg aagttccttt gggaccttta cctcccccga gccccaagat    240
gatgcttgga cctgtgactc tgcacctggt tgggcattta ctggctttcc tagacttgct    300
ttgcccccgt ggccccattc attcaatctt gccaatgacc tttgaggctg tcaacaggac    360
catggcttca tgttgtaccg aacctatatg acccatacca tttttgagcc aacaccattc    420
tgggtgccaa ataatggagt ccatgaccgt gcctatgtga tggtggatgg ggtgttccag    480
ggtgttgtgg agcgaaatat gagag                                          505

<210> 419
<211> 2663
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (660)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (775)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1248)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1824)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2642)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2662)
<223> n equals a,t,g, or c

<400> 419
aattcggcag agcgactggg ggaagttcct gaaggatcac agttacaagg ctgctcccgt     60
cagctgtttc aagcacgtcc cactctatga ccagtgggag gatgtgatga aagggatgaa    120
ggtggaggtg ctcaacagtg atgctgtgct ccccagccgg gtgtactgga tcgcctctgt    180
catccagaca gcagggtatc gggtgctgct tcggtatgaa ggctttgaaa atgacgccag    240
ccatgacttc tggtgcaact ggggaacagt ggatgtccac cccattggct ggtgtgccat    300
caacagcaag atcctagtgc ccccacggac catccatgcc aagttcaccg actggaaggg    360
ctacctcatg aaacggctgg tgggctccag gacgcttccc gtggatttcc acatcaagat    420
ggtggagagc atgaagtacc cctttaggca gggcatgcgg ctggaagtgg tggacaagtc    480
ccaggtgtca cgcactcgca tggctgtggt ggacacagta atcgggggtc gcctacggct    540
cctctacgag gatggtgaca gtgacgacga cttctggtgc cacatgtgga gccccctgat    600
ccacccagtg ggttggtcac gacgtgtggg ccacggcatc aagatgtcag agaggcgaan    660
tgacatggcc catcacccca ccttccggaa gatctactgt gatgccgttc cttacctctt    720
caagaaggta cgagcagtct acacagaagg cggttggttt gaggaaggga tgaanctgga    780
ggccattgac cccctgaatc tgggcaacat ctgcgtggca actgtctgta aggttctcct    840
ggatggatac ctgatgatct gtgtggacgg ggggccctcc acagatggct tggactggtt    900
ctgctaccat gcctcttccc acgccatctt cccggccacc ttctgtcaga agaatgacat    960
tgagctcaca ccgccaaaag gttatgaggc acagactttc aactgggaga actacttgga   1020
gaagaccaag tcgaaagccg tccatcgaga ctctttaaca tggattgccc aaaccatggc   1080
ttcaaggtgg gcatgaagct ggaggccgtg gacctgatgg agccccggct catctgtgtg   1140
gccacggtga aacgagtggt gcatcggctc ctcagcatcc actttgacgg ctgggacagc   1200
gagtacgacc agtgggtgga ctgcgagtcc ccagacatct accccgtncg gctggtgtga   1260
gctcaccggc taccagctcc agcctcctgt ggccgcagaa ccggccacac cgytgaaggc   1320
caaagaggcc acaaagaaga aaaagaaaca gtttgggaag aaaaggaaaa gaatcccgcc   1380
cactaagacg cgacccctca gacaggggtc caagaagccc ctgctggagg acgaccctca   1440
gggtgccagg aagatctcgt cggagcctgt tcctggcgag atcattgctg tgcgtgtgaa   1500
ggaagagcat ctagacgtgg cctcgcccga caaggcttca agtccagagc tgcctgtctc   1560
cgtcgagaac atcaagcagg aaacagacga ctgagccttc ctgcctccag cctggcttct   1620
agctggaagc cagcccagcg tttctctacc accaccacca tgcctccacc tgactttggc   1680
ttggagactg atcctctctg tgtaaattct gcccggtgct gtgaaggctg gacggtggag   1740
gacctgctgg ggtctcctgg gacccgcctg ttgcttctgc cctcccctgt ggaaaggtct   1800
atatgacggg ccgcctgagg cccnagaact cgtctgtgaa ccaccttttc cagccagagt   1860
tcccaaagct ggaacgctag ctgcctgctc ttccttaaga tggcctcccc ccgacccgcc   1920
acggccctca gttgccaggg atggggccac cactgtcaca ctgtggaata caagacagtg   1980
aactctgtct gcctgaacga gtcatgtaaa ttaagttcta gagcagctct ctgagcagga   2040
taaggtcccc tgacagtgag ttgtgtggtg ggggcagcct ctgcctcaaa aattcaccaa   2100
gcagaatgcc tctcagcctc atgtgttggt cctctgctcc tcctagctcc ccagggatgt   2160
tggggaccca gcttgtctcg gcagctaaga agcagtgacc aggatgtgga ttttggcgac   2220
ctgtgtggtg gccttgagct gctttctgtg tttgtgagga ctgactccca tttcctaaag   2280
gaaatgcccc cggggaggac attgggagga agatggcctg agtgtgcact ttggctctgc   2340
tacctgctcc tgaagccccg ctaaaaataa ttcatccaag attcctttgt agttaaaggg   2400
tccagttctg actggagcct ctagagagct gggcttgtat gttcttttgg ccttttgttc   2460
ctacctaaat gaagaaacca tgcctggagg ggccgtgaac acagaaccct caagacaagg   2520
atgacagagc tggaggacac atctagctgc cattgcaacc tcactgggct ccccagactc   2580
tgtgtgtgag aaattaaacc ccctgcttgc ttgagtcccg tttgttaagg attcttctat   2640
tnccttgnca gatttgtgtt cng                                           2663

<210> 420
<211> 479
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (393)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (456)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<400> 420
ggcgagacca ctaatctacc ggcagacacc aattccagac acattattaa ggtgctgcgg     60
atggcaatcc tgctgtcyta ctgctctatc ctgtgtaact acaaggccat cgaaatgccc    120
tcacaccaga cctacggagg gagctggaaa ttcctgacgt tcattgatct ggttatccag    180
gctgtctttt ttggcatctg tgtgctgact gatctttcca gtcttctgac tcgaggaagt    240
gggaaccagg agcaagagag gcagctcaag aagctcatct ctctccggga ctggatgtta    300
gctgtgttgg cctttcctgt tggggttttt gttgtagcag tgttctggga tcattatgcc    360
tatgacagag agatgatata cccgaagctg ctngataatt tatcccaggg ggctgaatca    420
cggatgcatt caaagcttaa agtttcttgg cacgcntttc aaagnccact gacttttga     479

<210> 421
<211> 587
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (515)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (517)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (553)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<400> 421
ccagaagtaa ccctaggctc aatggagggg tctggggacc atggtataaa gaggaaacca     60
agaaaaagaa gccaagcaaa aatcaggctg agaaaaagca aaagaaaagc aaaaaaaaga    120
agaagaaaca gcagaaagca gtytcaggta aaccagcaaa tttggctcga taatatcgct    180
rgcctaagcg tcargcttgk tttcatgctg tgccactcca gagacttctg ccacctggcc    240
gccacactga aaactgtcct gctcagtgcc aaggtgctac tcttgcaagc cacacttaga    300
gagagtggrg atgkttattt ctctygctcc tttagaaaac gtggtgagtc ctgagttcca    360
ctgctgkgct tcagtcaact gaccaaacac tgctttgaat tataggagga gaacaataac    420
ctaccatccg caagcatgct aattgatgga agttacaggt agcagattaa aactaccttt    480
gataaattac agtcaaagat tgtgtcacct caaangnctg aagaatatat ttcctggtgg    540
aattttgtaa ggnctgtcat atgacactgg ggtttttaat aattcna                  587

<210> 422
<211> 1901
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1160)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1892)
<223> n equals a,t,g, or c

<400> 422
ggtttgataa cagtgagagc tattaatttt agaaaagtcg agttactttg taatgtagtt     60
aaagaacaag ggagaatgcg tagtgtaaaa aatactgttg agttagctgc tcactgtatt    120
tcacaactga tcaatattcg ggccaatatg gacttaaagg gctatgtttt gaacacagct    180
agatgacaaa ttaaatatga atggtgaagg aaatgtacta attatttatt catataatct    240
tttcttggca ttgagttaaa gtctaagaag caggtttcag agattaggat actatcagaa    300
tttaaactta atggaattta atctctagca tgtcctaatg cagacaactt gcaattccag    360
ggtttataaa tcataccagg gtattaaagc acagtaatca gatgtgtcag tggtaaatat    420
gtgtgaaata atgaatcata tgactgctct gttaagtgtt tggttcttta ttggggtgca    480
tttataccct tttatgatta ataagttagt atatatagtt atcacagtaa ttatcttctc    540
caaaatgttt ctaaaaataa ttattgtgat cacttctgtt attgcccagc gagagttggg    600
gatagatttt attcagttaa cactgtatgt aattagggtt ttttttattt cttcttcagt    660
tggcagttct gcaagtagta gtgccacaag gagagagtct ctatctacta gctctgactt    720
gtacaaaaga tctagtagca gcctagcacc catagggcaa ccattttaca atagtctggg    780
attttcctcc tctccaagtc caataggcat gcctctgcca agccaaactc caggacattc    840
acttacgcca ccgscatcac tttcatcaca tggatcctca tccagtttgc atttaggtaa    900
aaaaaaacca aaaccctttt tatttgtatg tatacatgta tgtgtgtttg tgtgtgtgtt    960
tataatatat gtaaaatatt taatgttggt taaaacatgc caaattgctt ttgcttttag   1020
atattagtct tttgaaaaag ttctactttc ctgaaaattc aaagtgaggg tctaatgtac   1080
aataaggtaa agacccccct attgtttctt atgttttttt tatgaaatat aatggtgtgt   1140
tttttcttgt ctgtgctttn gatttgtgtg ttttagagca tctgaaaagt caactatata   1200
aacataatag tgaaagagaa attcactatc aaaagatttg cacaccataa gaaaaacatt   1260
agttacatag ctactgaact aggttagtac actggttttt gctttggtct ttctatgcct   1320
ggccatttta ccagataatt atttcagtga atttgaattt agtgtatttg tcacttaagg   1380
aagcttatag gcttgggcca tatacttctt ttttggatat gttaaagaaa aaaaatgttt   1440
taggcttgtt gtmcccctga agttggagca ttgagaactt tgtttatatt tgtatattaa   1500
aattgttccc acccccaaat tattaaattg gtgattacct tttttccctc tccaggaagt   1560
atttatccat gtagataata cgttttgaag ggctttggat atcaggggct gtgtatgaat   1620
ccctatcttg tcaaagaaat tattttttta aaactttatt ttgaattttt ataattctag   1680
ttattcagct gaaactgagg gattctattg ccagctttta tgtaattgga aagatttaaa   1740
tcagcttgtg ttttaaaaag taatgttgct actgtaagca gatgtactgt aagttagtga   1800
ttatgtttga ccaccccctc caattacatg ggtatagcta tttaaaaaaa aaaaaaaaaa   1860
ctcgaggggg ggcccgtacc caatcgccct gngatgagtc t                       1901

<210> 423
<211> 1498
<212> DNA
<213> Homo sapiens

<400> 423
gttagctact gagtggcaca tcttcagtac gcatgattcg tgggggactc aggcagaggt     60
aaaagtgtga aacttttcag cattacctaa gaagcaaagg ctcaattttg gctgcttcat    120
tcttatctct tctgccacag ttctaacgtg cctgatctac tgagaccaag gatgaccaat    180
gactcagaag ggaaaatggg atttaaacac ccaaagatca tggggaattt cagaggtcat    240
gccctccctg gaaccttctt ttttattatt ggtctttggt ggtgtacaaa gagtattctg    300
aagtatatct gcaaaaagca aaagcgaacc tgctatcttg gttccaaaac attattctat    360
cgattggaaa ttttggaggg aattacaata gttggcatgg ctttaactgg catggctggg    420
gagcagttta ttcctggagg gccccatctg atgttatatg actataaaca aggtcactgg    480
aatcaactcc tgggctggca tcatttcacc atgtatttct tctttgggct gttgggtgtg    540
gcagatatct tatgtttcac catcagttca cttcctgtgt ccttaaccaa gttaatgttg    600
tcaaatgcct tatttgtgga ggcctttatc ttctacaacc acactcatgg ccgggaaatg    660
ctggacatct ttgtgcacca gctgctggtt ttggtcgtct ttctgacagg cctcgttgcc    720
ttcctagagt tccttgttcg gaacaatgta cttctggagc tattgcggtc aagtctcatt    780
ctgcttcagg ggagctggtt ctttcagatt ggatttgtcc tgtatccccc cagtggaggt    840
cctgcatggg atctgatgga tcatgaaaat attttgtttc tcaccatatg cttttgttgg    900
cattatgcag taaccattgt catcgttgga atgaattatg ctttcattac ctggttggtt    960
aaatctagac ttaagaggct ctgctcctca gaagttggac ttctgaaaaa tgctgaacga   1020
gaacaagaat cagaagaaga aatgtgactt tgatgagctt ccagtttttc tagataaacc   1080
ttttcttttt tacattgttc ttggttttgt ttctcgatct tttgtttgga gaacagctgg   1140
ctaaggatga ctctaagtgt actgtttgca tttccaattt ggttaaagta tttgaattta   1200
aatattttct ttttagcttt gaaaatattt tgggtgatac tttcattttg cacatcatgc   1260
acatcatggt attcaggggc tagagtgatt tttttccaga ttatctaaag ttggatgccc   1320
acactatgaa agaaatattt gttttatttg ccttatagat atgctcaagg ttactgggct   1380
tgctactatt tgtaactcct tgaccatgga attatacttg tttatcttgt tgctgcaatg   1440
agaaataaat gaatgtatgt attttggtgc agacaaaaaa aaaaaaaaaa aaaaaaaa     1498

<210> 424
<211> 2348
<212> DNA
<213> Homo sapiens

<400> 424
gagctccggg ggccgctgca gccgcccaag cgcccgccat gcgcgctgcc cgcgccgcgc     60
cgctgctcca gctgctgctc ctgctggggc cgtggctgga ggctgcgggc gttgcggagt    120
cgccgctgcc cgccgtggtc cttgccatcc tggcccgcaa tgccgaacac tcgctgcccc    180
actacctggg cgctctggag cggctggact acccccgggc caggatggcc ctctggtgtg    240
ccacggacca caatgtggac aacaccacag agatgctgca ggagtggctg gcggctgtgg    300
gcgatgacta tgctgctgtg gtctggaggc ctgagggcga gcccagttct acccagatga    360
agagggtccc aagcactgga ccaaagaaag gcaccagttt ctgatggagc tgaagcagga    420
agccctcacc tttgccagga actggggggc cgactatatc ctgtttgcag acacagacaa    480
cattctgacc aacaatcaga ctctgcggct tctcatgggg caggggcttc cagtggtggc    540
ccaatgctgg actcccagac ctactactcc aacttctggt gtgggatcac cccccagggc    600
tactaccgcc gcacagccga gtacttcccc accaagaacc gccagcgccg gggctgcttc    660
cgtgtcccca tggtccactc caccttcctt gcatccctgc gggctgaagg ggcagaccag    720
cttgctttct acccgccaca tcccaactac acttggcctt tcgacgacat catcgtcttc    780
gcctatgcct gccaggctgc tggggtctcc gtccacgtgt gcaatgagca ccgttatggg    840
tacatgaatg tgccggtgaa atcccaccag gggctggaag acgagagggt caacttcatc    900
cacctgatct tagaagcact agtggacggc ccccgcatgc aggcctcagc tcatgtgact    960
cggccctcta agaggcccag caagataggg tttgacgagg tctttgtcat cagcctggct   1020
cgcaggcctg accgtcggga acgcatgctc gcctcgctct gggagatgga gatctctggg   1080
agggtggtgg acgctgtgga tggctggatg ctcaacagca gtgccatcag gaacctcggc   1140
gtagacctgc tcccgggcta ccaggaccct tactcgggcc gcactctgac caagggcgag   1200
gtgggctgct tcctcagcca ttactccatc tgggaagagg tggttgccag gggcctggcc   1260
cgggtcctgg tgtttgagga tgacgtgcgc tttgagagca acttcagggg gcggctggag   1320
cggctgatgg aggatgtgga ggcagagaaa ctgtcttggg acctgatcta ccttggacgg   1380
aaacaggtga accctgagaa ggagacggcc gtggaggggc tgccgggcct ggtggtggct   1440
gggtactcct actggacgct ggcctatgcc ctgcgtctgg cgggtgcccg caagctgctg   1500
gcctcacagc ctctgcgccg catgctgccc gtggacgagt tcctgcccat catgttcgac   1560
cagcacccca acgagcagta caaggcacac ttctggccac gggacctggt ggccttctcc   1620
gcccagcccc tgctcgctgc ccctacccac tatgccgggg acgccgagtg gctcagtgac   1680
acggagacat cctctccatg ggatgatgac agcggccgcc tcatcagctg gagcggctcc   1740
caaaagaccc tgcgcacccc gcctggacct gactggcagc agcgggcaca gcctccaacc   1800
ccagccccga gatgagctct aggtccaggt gatgactgca aagcatggtc caggagcagg   1860
ccactactgc ccagagagca gaggaggagg ttgttggcag ggactcagat cctgtcagac   1920
ctggccacca ccttgggcat ggccactctg ccctctggac ctgtctttca tcgggagaaa   1980
ccactcagag atggatccca ttccctaaaa ggtctcacag caaaggagca ggactcccag   2040
gcccctgtac cctgcctggc ctgattcagg gccttgtggc ccccagcttc tgtttcaagc   2100
tgggcagacc ccaggatccc ttccctccct aaggactcag ctgaggggcc cctctgcccc   2160
cttctacctc cacctcagca ccctccccca gcttgatgtt tgggtctccc cagcaccctc   2220
ctccctggcc ggtgcaaagt acagggaggt aaagcaggac ccttgcagac atgttgccca   2280
gcacacagta ggccctcaat aaaagccatt tgcactttaa aaaaaaaaaa aaaaaaaaaa   2340
aaaaaaaa                                                            2348

<210> 425
<211> 789
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (788)
<223> n equals a,t,g, or c

<400> 425
agnctcgccg cgatgccccg ccccactctc cacccgctga atgcagggcg catgctgcta     60
cttggcggct caagcccgcc cgcaccgtcc ccattctctg accgcccctc tcccggtaca    120
ctgcgcaggc acaacagagc cgctcccctc tcctcgcccc gccaccggga cggagagcgc    180
ccgccgctgc atttccggcg acacctcgca gtcattcctg cggcttgcgc gcccttgtag    240
acagccgggg ccttcgtgag accggtgcag gcctggggta gtctcctgtc tggacagaga    300
agagaaaaat gcaggacact ggctcagtag tgcctttgca ttggtttggc tttggctacg    360
cagcactggt tgcttctggt gggatcattg gctatgtaaa agcaggcagc gtgccgtccc    420
tggctgcagg gctgctcttt ggcagtctag ccggcctggg tgcttaccag ctgtctcagg    480
atccaaggaa cgtttgggtt ttcctagcta catctggtac cttggctggc attatgggaa    540
tgaggttcta ccactctgga aaattcatgc ctgcaggttt aattgcaggt gccagtttgc    600
tgatggtcgc caaagttgga gttagtatgt tcaacagacc ccattagcag aagtcatgtt    660
ccagcttaga ctgatgaaga attaaaaatc tggmatcttc cactattttc aatatattaa    720
gagraataag tgcascattt ttgsatctga cattttacct aaaaaaaaga caccaacttg    780
gcagagang                                                            789

<210> 426
<211> 1016
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1010)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1015)
<223> n equals a,t,g, or c

<400> 426
ctgcaggaat tcggcacgag atcatattta ggaattaaat ttgatgttgt caaaggaatc     60
ataagaaact cttctcacgt gactattaac cttcatagca gtatggaaat ggtatcagaa    120
ttgaaatttt tgaggaccag tgttggtatt tgtggtaata gagatctaga gaccccatct    180
ggccaaaaat agtttcttat gtcatgtttt ttgttgttgt tgtgtttttt tgtttttttt    240
ttgttttttt tttttgagat ggagtcttgc tctgtcacca ctgcactcca gcctgggcaa    300
cagagtgaga ctcctgtctc aaaaaataaa taaataaata aatcaaaagm caagcgcttt    360
ggtcacagtt tattaaataa atgwatagaw atattactgc agcccccaaa agttgtaaat    420
aactgttgtg ttacatgagt ggatttattt taaaattgtc ttctccttga gttaaagctg    480
caaaactttc tgttgktgtt ggctgggcac agtggcttat gcctataatc ccagcacttt    540
ggraggctga ggcaagttca ccaggcgtag tggcacatgc ctgtagtccc agctacttgg    600
aaggctgagg tgggagggtc acttgagcct agaaggtcga ggctgcagtg aactgtgtat    660
atgtatgtgt gtgtgcatat atatatttat attttcatca ttaccatatt tgtgaaattc    720
attagtatca atggagaact aggaaaacta aggaaatttg ataggaattt gtcatcagtg    780
attgtgctgc acaatctatt tcctttctgc tttgcgaatt tgtcatcagt gatggtactg    840
cacaatctat ttcctttctg ttttgcactg tgtttagtga gccttaatat atatgttact    900
ggttacattc tggtcatatt gttaaaaagt agacarctaa tgagcaccat atttttcaca    960
aactggatta caagagagat cataaaggag ttttgccttt actccccttn cccgna       1016

<210> 427
<211> 1258
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (182)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1020)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1181)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1208)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1210)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1240)
<223> n equals a,t,g, or c

<400> 427
ctcgcgctgc tctggccctg caggttgtgt tyccgcctct accccgcctc cattccgttg     60
ctctctcagt ctcagacccg ggctctcggt ccgccgcttc aggtcttggc gcmstcagag    120
agttggcgcg gctctgtgtt gaccaaacct agtggatgca gttagcgccg gagcccggcc    180
cngcccgtca ccagggttat tcccgccttc taggtttgcc aggactgccg gccctgcagc    240
tgccttctgc cccaggtttt tggctactga tgttacaaac aataaaatat tggagcatag    300
agttgaagaa cagactcaaa ccaggttttt atttaattag ttaaaaatat ggatcctgag    360
acaaggggac aagagattat caaagtgaca cctcttcaac aaatgcttgc ctcatgtact    420
ggagctatac tgacatcagt aatagtgaca cccctggatg ttgttaaaat tagactccaa    480
gcccaaaaca acccactccc caaaggaaaa tgttttgtat atagtaatgg actcatggat    540
catctatgtg tctgtgaaga gggaggcaac aaactatggt ataagaagcc aggaaatttc    600
cagggaacat tggatgcatt ttttaaaatc attcgaaatg agggcattaa atctctatgg    660
agtggccttc ctcctaccct agtgatggca gttcctgcca cagttattta ttttacctgc    720
tatgatcaat taagtgctct tctgagatct aagttaggag aaaatgaaac ctgcatacca    780
attgttgctg gaattgtagc cagatttggt gcagtaactg kgataagtcc actagaattg    840
attagaacca agatgcagtc caagaagttt tcttacgtgg aactgcatcg atttgtcagc    900
aagaaagtat ctgaagatgg ttggatttcc ctttggargg gctgggctcc tactgktctt    960
agagatgtac ctttctcagt ttctatgcct ttgcatatgt caacctggat tataatgaan   1020
aacattgttg ctaaaaatgg attttccgga ttattttcag gcctaattcc tcgcttaatt   1080
aaaattgctc ctgcttgtgc cattatgatc agtacatatg aatttggaaa ggcttttttc   1140
cagaaacaaa atgttcgaag gcagcaatac taagtgatgc ngtttcaact tgaaaccaac   1200
tatagccnan gaagatggag actcttaagc caagaatggn tttcaccatt attctctc     1258

<210> 428
<211> 881
<212> DNA
<213> Homo sapiens

<400> 428
tagtggatcc cccgggctgc aggaattttt tcctttagca agcgccgccg ggatgaccgt     60
cggccttgcc gtttgtgcat tgattgtcgg gctggcgctg gcgatgttct ttgcggtatg    120
ggagtcggca aaatggcgtc ctgtcgcgtg ggcaggttca gcgctggtaa ccattctgcg    180
tggcctgcca gaaattctgg tggtgctgtt tatctatttt ggctcctcgc agctgctgct    240
gacgctttcg gatggcttca ctatcaatct tgggttcgtg cagatcccag tgcagatgga    300
cattgagaac ttcgacgtta gcccgttcct ttgtggtgtc atcgctctgt cactgctgta    360
tgccgcctat gcctcgcaaa cgcttcgggg cgcgttgaaa gcggtgccgg tgggtcagtg    420
ggagtctggt caggcgctgg ggctgtcgaa atcggctatc tttttccgtc tggtgatgcc    480
gcagatgtgg cgtcatgcgc tgcctggcct cggtaaccag tggctggtgc tgctgaaaga    540
taccgcgctg gtcagtttga ttagtgtgaa tgatttaatg ctgcaaacaa aaagcatcgc    600
tactcgtacc caggaaccat ttacctggta cattgtggcg gcggcgattt acctggtgat    660
caccctgctc agtcagtaca ttctcaaacg cattgacctg cgcgcgacac gttttgagcg    720
gaggcccagc taatgtttga gtatttaccc gaactgatga aagggctaca caccagcctg    780
acgctaaccg ttgcctcgct gattgtggca ctgattctgg cattgatttt taccatcatc    840
ctgacgctga aaacgccggt gctggtgtgg ctggtgcggg g                        881

<210> 429
<211> 874
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (730)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (732)
<223> n equals a,t,g, or c

<400> 429
gcgtccggag ctgctaggct ccgacattct cacttgccag tgggacctgt cttggagcgc     60
cgcgccgccc gcctgccaaa agatcatgac ttgtgctgac cctggcgaga ttgccaacgg    120
gcaccgcacc gcctcggacg ccggcttccc cgttggctcc cacgtccagt accgctgcct    180
gccagggtac agcctcgagg gggcagccat gctcacctgc tacagccggg acacaggcac    240
acccaagtgg agcgataggg tccccaaatg cgccttgaag tacgagccgt gcctgaaccc    300
gggggttccc gagaatggct accagacgct gtacaagcac cactaccagg cgggcgagtc    360
tctgcaaagt tgcctatgag gagctcctgg acaaccgaaa actggaagtg acccagacca    420
cagatccatc acggcagctg gaagggggga acctggccct ggccatcctg ctgcctctag    480
gcttggtcat tgtcctcggc agtggcgttt acatctacta caccaagctt cagggaaagt    540
cccttttcgg cttctcgggc tcccactcct acagccccat caccgtggag tcggacttca    600
gcaacccgct gtatgaagct ggggatacgc gggagtatga agtttccatt tgaaccccaa    660
gactacagct gcaggaccca ggacgcccct cccctcctca ttcgggcaga gggaaatacg    720
ggacccggtn tntgcctcct ggctgccctc ctccctggct gtgtaaatag tctccctatc    780
ccacgagggg gctttgatgg ccctggagat cctacagtaa ataaaccagc atcctgccgc    840
ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa                                874

<210> 430
<211> 1600
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1551)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1563)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1582)
<223> n equals a,t,g, or c

<400> 430
tcggcgcagg tttccgcagc tgagggggca gctccgcggc ggcgtccggg gtctccagta     60
gggctgacgc tccggtgctc gcacaatccc ccgcctcggc tggcaacggg cgtccctcca    120
ctccccgagt ccccggcagc cgccgccacc ccagcgcgcc ccgatctggc cccctgcccc    180
gcgaagatgg ctgccgtacg ccgggcccgc agttattgcc gctgcctggt gcgcttctcc    240
gaccgagaac tctgctaagc tccgctgcag agacaggcag gagtagacac ccggacaccc    300
agcacccctc ctccgggggg cggtgcagag ggggcacgga gagcccctcg agcgcagcag    360
gccgccccgc cagcatggca gaagctgagg aagattgtca ttctgatact gtcagagcag    420
atgatgatga agaaaatgaa agtcctgctg aaacagatct gcaggcacaa ctccagatgt    480
tccgagctca gtggatgttt gaacttgctc caggtgtaag ctctagcaat ttagaaaatc    540
gaccttgcag agcagcaaga ggctctctcc agaaaacatc ggcagatacc aaaggaaaac    600
aagaacaggc aaaagaagaa aaggctcgag aactcttcct aaaagcagta gaagaagaac    660
aaaatggagc tctctatgaa gccatcaagt tttatcgtag ggctatgcaa cttgtacctg    720
atatagagtt caagattact tatacccggt ctccagatgg tgatggcgtt ggaaacagct    780
acattgaaga taatgatgat gacagcaaaa tggcagatct cttgtcctac ttccagcagc    840
aactcacatt tcaggagtct gtgcttaaac tgtgtcagcc tgagcttgag agcagtcaga    900
ttcacatatc agtgctgcca atggaggtcc tgatgtacat cttccgatgg gtggtgtcta    960
gtgacttgga cctcagatca ttggagcagt tgtcgctggt gtgcagagga ttctacatct   1020
gtgccagaga ccctgaaata tggcgtctgg cctgcttgaa agtttggggc agaagctgta   1080
ttaaacttgt tccgtacacg tcctggagag agatgttttt agaacggcct cgtgttcggt   1140
ttgatggcgt gtatatcagt aaaaccacat atattcgtca aggggaacag tctcttgatg   1200
gtttctatag agcctggcac caagtggaat attacaggta cataagattc tttcctgatg   1260
gccatgtgat gatgttgaca acccctgaag agcctcagtc cattgttcca cgtttaagaa   1320
ctaggaatac caggactgat gcaattctac tgggtcacta tcgcttgtca caagacacag   1380
acaatcagac caaagtattt gctgtaataa ctaagaaaaa agaagaaaaa ccacttgact   1440
ataaatacag atattttcgt cgtgtccctg tacaagragg cagatccaka gttttcmtgt   1500
gggggctaca gctatgttcc cmgtggtcac cmgaggtttc aacmaactca ntttggggta   1560
ccntcatttc tttgttcaac anttacttta cccaattcac                         1600

<210> 431
<211> 1470
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1346)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1347)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1357)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1387)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1415)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1454)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1462)
<223> n equals a,t,g, or c

<400> 431
gtggacacgg aagtggtcgt cgtcgcggca ccggtgggag ctaggcgcga ggctcggagt     60
gcggccagcg ggcggaggcg gtctcgcatc ggcggcgacg gagggctcag gcgtcgtcgt    120
ttgggtgggg ggccgctgaa ctgacaagcg acatttcagc tcctttcacc cgccggaacc    180
ccggagccgg ggcccgctca gccggcgtta ccatgaccaa ggccggtagc aagggcggga    240
acctccgcga caagctggac ggcaacgaac tggacctgag cctcagcgac ctgaatgagg    300
tcccggtgaa ggagctggct gcccttccaa aggccaccat cctggatctg tcttgtaata    360
aactgactac tctaccgtcg gatttctgtg gcctcacaca cctggtgaag ctagacctga    420
gtaagaacaa gctgcagcag ctgccagcag actttggccg tctggtcaac ctccagcacc    480
tggatctcct caacaacaag ctggtcacct tgcctgtcag ctttgctcag ctcaagaacc    540
tgaagtggtt ggacctgaag gataaccccc tggatcctgt cctggccaag gtggcaggtg    600
actgcttgga tgagaagcag tgtaagcagt gtgcaaacaa ggtgttacag cacatgaagg    660
ccgtgcaggc agatcaggag cgggagaggc agcggcggct ggaagtagaa cgtgaggcag    720
agaagaagcg tgaggctaag cagcgagcta aggaagctca ggagcgggaa ctgcggaagc    780
gggagaaggc ggaagagaag gagcgccgga gaaaggagta tgatgccctc aaagcagcca    840
agcgggagca ggagaagaaa cctaagaagg aagcaaatca ggccccgaaa tctaagtctg    900
gctcccgtcc ccgcaagcca ccaccccgga agcacactcg ttcctgggct gtgctgaagc    960
tgctgctgct gctgctgcta tttggtgtgg cgggagggct ggttgcttgt cgggtgacag   1020
agctgcagca gcagcccctc tgcaccagcg tgaacaccat ctatgacaat gcggtccagg   1080
gtctacgccg ccatgagatc ctccagtggg tcctccagac cgactctcag cagtgagctt   1140
gtccccagca cctgctgcct cccagccttg gagtttggat tcctatggaa ttgggttctg   1200
ctggacacaa cctcttttta gcatcagacc tacctgccat catcaaatgg ctgcagattg   1260
gtacatgaga ccttctcttt gtaggacttc ttcattcctt agtcagggtt ccctgaagga   1320
atgaggagaa atgggaggtg gccggnnggg ccgtggnggc aagttacctg catgcctaaa   1380
ggagtangct tgggggtggg agagagaaaa catanctttt tagtgtatat aagttgggaa   1440
aggcaaggtt ggtntactaa anggcagttg                                    1470

<210> 432
<211> 454
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (405)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (439)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (454)
<223> n equals a,t,g, or c

<400> 432
gaggggaagc agatctgagg acatctctgt gccaggccag aaaccgccca cctgcaggaa     60
tcccagccat tcccgggatc cgaggaccca aagggcagaa gggagaaccc ggcttacccg    120
gccatcctgg gaaaaatggc cccatgggac cccctgggat gccaggggtg cccggcccca    180
tgggcatccc tggagagcca ggtgaggagg gcagatacaa gcagaaattc cagtcagtgt    240
tcacggtcac tcggcagacc caccagcccc ctgcacccaa cagcctgatc agattcaacg    300
cggtcctcaa caacccgcag gagattatga cacgagcact ggcaagttca actgcaaagt    360
ccccggctct aataatttgt ctaacaagcg tcgcatacag ccaantgtgc gtgtgctgta    420
ccgcagcggc gtcaaagtng tcacttctgt gggn                                454

<210> 433
<211> 1963
<212> DNA
<213> Homo sapiens

<400> 433
ggagagagag agagagagag agctcgtgcc gtttgtatac agcttgtgca ggaatacggc     60
ctgatagatg cctgccagtg tgtattgatg tgggaactga taatatcgca ctcttaaaag    120
acccatttta catgggcttg taccagaaac gagatcgcac acaacagtat gatgacctga    180
ttgatgagtt tatgaaagct attactgaca gatatggccg gaacacactc attcagttcg    240
aagactttgg aaatcataat gcattcaggt tcttgagaaa gtaccgagaa aaatattgta    300
ctttcaatga tgatattcaa gggacagctg cagtagctct agcaggtctt cttgcagcac    360
aaaaagttat tagtaaacca atctccgaac acaaaatctt attccttgga gcaggagagg    420
ctgctcttgg aattgcaaat cttatagtta tgtctatggt agaaaatggc ctgtcagaac    480
aagaggcaca aaagaaaatc tggatgtttg acaagtatgg tttattagtt aagggacgga    540
aagcaaaaat agatagttat caggaaccat ttactcactc agccccagag agcatacctg    600
atacttttga agatgcagtg aatatactga agccttcaac tataattgga gttgcaggtg    660
ctggccgtct tttcactcct gatgtaatca gagccatggc ctctatcaat gaaaggcctg    720
taatatttgc attaagtaat cctacagcac aggcagagtg cacggctgaa gaagcatata    780
cacttacaga gggcaggtgt ttgtttgcca gtggcagtcc atttgggcca gtgaaactta    840
cagatgggcg agtctttaca ccaggtcaag gaaacaatgt ttatattttt ccaggtgtgg    900
ctttagctgt tattctctgt aacacccggc atattagtga cagtgttttc ctagaagctg    960
caaaggccct gacaagccaa ttgacagatg aagagctagc ccaagggaga ctttacccac   1020
cgcttgctaa tattcaggaa gtttctatta acattgctat taaagttaca gaatacctat   1080
atgctaataa aatggctttc cgatacccag aacctgaaga caaggccaaa tatgttaaag   1140
aaagaacatg gcggagtgaa tatgattccc tgctgccaga tgtgtatgaa tggccagaat   1200
ctgcatcaag ccctcctgtg ataacagaat agaagcactc ccctgataaa tactttctgt   1260
gctccaggga accccttttt tcagacaaga agagataatg tcttcagttt tatggtgttt   1320
tctgtgtttt gttctccctg accactttgg ttgatgtatt ttttccatgc gtctccacat   1380
ctgttggggt agacgtgttg attgattgca ttgcccacca gcaccctaca rtcagatagt   1440
tgtgatgctt taattctaac atacagcccg taccacatcc aggagatgta aaaagtgtgt   1500
ttgtgaatgt cttcacttgt actctaattc agacttgcca aagtatttgc tatttactat   1560
tatgggtaat actcttctct ggcctagttc ttacagagct actaaaatag aaatttactt   1620
ttatggatag aagtacagaa ttttgagaag aaactaaatt ttcaccaaat tttaaggaaa   1680
aattgtcatt atctaaaaat gttcttatat atctgcttca tcttaccttc atactctgaa   1740
attccctata gcagacagag ctagggaaat attaaaaatt taccctattt attttctgga   1800
actaaatcaa gccttaacta taacattatg agagtaatgg gaactactgc tggctttaag   1860
taaataaaag tcattgtttt caacagtgta taaaaatcat agtgtaacct ttttatttaa   1920
taaatatctt acatttaaaa aaaaaaaaaa aaaaaactcg tag                     1963

<210> 434
<211> 1382
<212> DNA
<213> Homo sapiens

<400> 434
aattcggcac gagcggaggc gagggaaact ragggcgaaa gttgtgtgtc gtgttggcag     60
gagggcctag aagggaaaga ctgtctagtg ggacaatgtc atattataaa tttggaatgc    120
tgaatagaaa attatagatt ttgatattga aggaaatgaa gcgaagccta aatgaaaatt    180
cagctcgaag tacagcaggc tgtttgcctg ttccgttgtt caatcagaaa aagaggaaca    240
gacagccatt aacttctaat ccacttaaag atgattcagg tatcagtacc ccttctgaca    300
attatgattt tcctcctcta cctacagatt gggcctggga agctgtgaat ccagagttgg    360
ctcctgtaat gaaaacagtg gacaccgggc aaataccaca ttcagtttct cgtcctctga    420
gaagtcaaga ttctgtcttt aactctattc aatcaaatac tggaagaagc cagggtggtt    480
ggagctacag agatggtaac aaaaatacca gcttgaaaac ttggaataaa aatgatttta    540
agcctcaatg taaacgaaca aacttagtgg caaatgatgg aaaaaattct tgtccaatga    600
gttcgggagc tcaacaacaa aaacaattaa gaacacctga acctcctaac ttatctcgca    660
acaaagaaac cgagctactc agacaaacac attcatcaaa aatatctggc tgcacaatga    720
gagggctaga caaaaacagt gcactacaga cacttaagcc caattttcaa caaaatcaat    780
ataagaaaca aatgttggat gatattccag aagacaacac cctgaaggaa acctcattgt    840
atcagttaca gtttaaggaa aaagctagtt ctttaagaat tatttctgca gttattgaaa    900
gcatgaagta ttggcgtgaa catgcacaga aaactgtact tctttttgaa gtattagctg    960
ttcttgattc agctgttaca cctggcccat attattcgaa gacttttctt atgagggatg   1020
ggaaaaatac tctgccttgt gtcttttatg aaatcgatcg tgaacttccg agactgatta   1080
gaggccgagt tcatagatgt gttggcaact atgaccagaa aaagaacatt ttccaatgtg   1140
tttctgtcag accggcgtct gtttctgaac aaaaaacttt ccaggcattt gtcaaaattg   1200
cagatgttga gatgcagtat tatattaatg tgatgaatga aacttaagta gtgataaaag   1260
gaagtttagc ataaattata gcagttttct gttattgctt aatttaccat ctccatagtt   1320
ttatagctac tattgtattt cacttgttga attaaagtat ttgaattctt ttaaaaaaaa   1380
aa                                                                  1382

<210> 435
<211> 1120
<212> DNA
<213> Homo sapiens

<400> 435
gcccagggct ctcggatgca gggagcctgg gcccaaacag cagcttccgg agtcggaagg     60
agctgaggaa gaagacwgac tgaaggagct tgcacttttc cgcctcggca accggaccca    120
gcagcaagca ggacgggcgg cgctctgcta ctggtcccgt taagccagag tagcccaagc    180
cctgaagtca ctgctcatcc ggaatggaaa tcccgccgac caactaccca gcctccaggg    240
cggccttggt ggcacagaac tacatcaact accagcaggg gaccccgcac agggtgtttg    300
aggtgcagaa ggtcaaacaa gccagcatgg aggatattcc aggaagagga cataagtatc    360
rccttaaatt tgctgttgaa gaaattatac aaaaacaagt taaggtgaac tgcacagctg    420
aagtacttta cccttcaacg ggacaagaaa ctgcaccaga agtcaacttc acatttgaag    480
gagaaactgg aaagaatcca gatgaagaag acaacacatt ttatcaaaga cttaagtcca    540
tgaaggaacc gctagaagca caaaatattc cagacaattt tggaaatgta tctccagaaa    600
tgacgctcgt tctacattta gcctgggttg cctgtggtta tataatatgg caaaattcta    660
ctgaagacac atggtataaa atggtaaaaa ttcaaactgt caagcaagtg caaagaaatg    720
atgactttat tgaattagac tacaccattc tacttcataa tatagcatct caggagatta    780
ttccctggca aatgcaagtt ctctggcatc cacaatacgg cactaaagta aaacataata    840
gccgtctgcc aaaggaagta caactggaat aaacaaaaac cctaacactg gaagtgtaaa    900
catgtctatt gatgtgtatg ccaatttcac tggcatctag cttatgaggc caaataatcc    960
caaagtgtca ctttatataa atgtcttgat tacagtatag aactttatag agtccataat   1020
acaaagtatc actacataaa aatgtcttta aaacagtaat agtggtatgt atatccaaaa   1080
taaaaagctt caatttcagc ctcaaaaaaa aaaaaaaaaa                         1120

<210> 436
<211> 1242
<212> DNA
<213> Homo sapiens

<400> 436
gtctagtggg agctccgcgt sgtagctacg ccggccgcct gsstttgaga caacgtgatt     60
ctccgcagct ggtcgcctac ccgtgatgtt ctgcccacgt cgagacctga gctgaaatgg    120
cagacgatct cggagacgag tggtgggaga accagccgac tggagcaggc agcagcccag    180
aagcatcaga tggtgaagga gaaggagaca cagaagtgat gcagcaggag acagttccag    240
ttcctgtacc ttcagagaaa accaaacagc ctaaagaatg ttttttgata caaccaaagg    300
aaagaaaaga gaataccacc aagaccagga aaagaagaaa gaagaaaatt actgatgttc    360
ttgcaaaatc agaaccaaaa ccagggttac ctgaagacct acagaagctg atgaaggact    420
attatagcag cagacgcttg gtgattgaat tagaagaact gaacctgcca gactcctgtt    480
tcctcaaggc caatgatttg actcacagtc tttcctcata cctaaaagaa atttgtccta    540
agtgggtaaa acttaggaag aaccacagtg agaagaaatc ggtcctgatg ctgatcatct    600
gcagctcggc cgtccgagcc ctggagctca ttaggtcgat gacagcattc agaggagacg    660
gcaaagttat aaaattattt gcaaagcaca taaaggtcca ggcgcaggta aagttgctgg    720
agaagcgtgt ggtgcacctg ggtgtaggaa ctccggggag aattaaagaa cttgttaaac    780
aaggtggcct taatttgagc cccttaaaat ttctggtttt tgactggaac tggagagatc    840
agaagttgag gagaatgatg gacattcccg agataagaaa ggaggtattc gaacttctgg    900
aaatgggagt gctcagtctg tgcaagtcag aatccttgaa actgggcctt ttctaagtct    960
gtgtcctaat gaagattcca gttttcacag tagaagttgc atcttattta atgactctga   1020
tacattgcaa gcactcagta aatatcagca aatagtttat gttaattgtg tcaacagatg   1080
gatcactgga atgtggggat tctgaaacag aaatgaaact gtccttttga caactctctt   1140
atataataaa gtatcaccgg cttgtgtatg aaaaaaaaaa aaaaaawaaa aaaaaaaaaa   1200
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                      1242

<210> 437
<211> 1985
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (360)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1985)
<223> n equals a,t,g, or c

<400> 437
ggcagaggag gagagagtga aggattccag aggacatccg gaacacggtg gggcaacgtg     60
cccttggagt ggtacgatga cttcccccac gtgggctacg acctggatgg caggcgcatc    120
tacaagcccc tgcggacccg ggatgagctg gaccagttcc tggacaagat ggacgatcct    180
gactactggc gcaccgtgca ggacccgatg acagggcggg acctgagact gacggatgag    240
caggtggccc tggtgcggcg gctgcagagt ggccagtttg gggatgtggg cttcaacccc    300
tatgagccgg ctgtcgactt sttcagcggg gacgtcatga tccacccggt gaccaaccgn    360
ccggccgaca agcgcarctt catcccctcc ctggtggaga aggagaaggt ctctcgcatg    420
gtgcacgcca tcaagatggg ctggatccar cctcgccggc cccgagaccc cacccccagc    480
ttctatgacc tgtgggccca ggaggacccc aacgccgtgc tcgggcgcca caagatgcac    540
gtacctgctc ccaagctggc cctgccagcc acgccgagtc gtacaaccca ccccctgaat    600
acctgctcag cgaggaggag cgcttggcgt gggaacagca ggagccaggc gagaggaagc    660
tgagcttttt gccacgcaag ttcccgagcc tgcgggccgt gcctgcctac ggacgcttca    720
tccaggaacg cttcgagcgc tgccttgacc tgtacctgtg cccacggcag cgcaagatga    780
gggtgaatgt agaccctgag gacctcatcc ccaagctgcc tcggccgagg gacctgcagc    840
ccttccccac gtgccaggcc ctggtctaca ggggccacag tgaccttgtc cggtgcctca    900
gtgtctctcc tgggggccag tggctggttt caggctctga cgacggctcc ctgcggctct    960
gggaggtggc cactgcccgc tgtgtgagga ctgttcccgt ggggggcgtg gtgaagagtg   1020
tggcctggaa ccccagcccc gctgtctgcc tggtggctgc agccgtggag gactcggtgc   1080
tgctgctgaa cccagctctg ggggaccggc tggtggcggg cagcacagat cagctgttga   1140
gcgccttcgt cccgcctgag gagcccccct tgcagccggc ccgctggctg gaggcctcag   1200
aggaggagcg ccaagtgggc ctgcggctgc gcatctgcca cgggaagcca gtgacgcagg   1260
tgacctggca cgggcgtggg gactacctgg ccgtggtgct ggccacccaa ggccacaccc   1320
aggtgctgat tcaccagctg agccgtcgcc gcagccagag tccgttccgc cgcagccacg   1380
gacaggtgca gcgagtggcc ttccaccctg cccggccctt cctgttggtg gcgtcccagc   1440
gcagcgtccg cctctaccac ctgctgcgcc aggagctcac caagaagctg atgcccaact   1500
gcaagtgggt gtccagcctg gcggtgcacc ctgcaggtga caacgtcatc tgtgggagct   1560
acgatagcaa gctggtgtgg tttgacctgg atctttccac caagccatac aggatgctga   1620
gacaccacaa gaaggctctg cgggctgtgg ccttccaccc gcggtaccca ctctttgcgt   1680
caggctcgga cgacggcagt gtcatcgtct gccatggcat ggtgtacaat gaccttctgc   1740
agaacccctt gctggtgccc gtcaaggtgc tgaagggaca cgtgctgacc cgagatctgg   1800
gagtgctgga cgtcatcttc caccccaccc agccgtgggt cttctcctcg ggggcagacg   1860
ggactgtccg cctcttcacc tagctgttct gcctgcctgg ggctggggtg gtcgtgctga   1920
agtcaacaga gcctttaccc tgtrmaaaaa aaaaaaaaaa aaaaaatcaa ggggggggcc   1980
gggtn                                                               1985

<210> 438
<211> 527
<212> DNA
<213> Homo sapiens

<400> 438
gaacgtgccg gttggcatca ctgaaggaga tggctcaagg actgggagtc tcccagcaag     60
ttctgtgcaa cttttgcaag actagctcct tgctggcccc cacatgcccc atgctaggcc    120
ccaatgttca gagctgggac ttgagctcac aaaactgggg agctgagaca tttgttctct    180
tggatctcac tctctctgtc ccttgtgcct ctgtagctgg ccttcttcct gccacaggcc    240
atgcctctac caaggacaca tggcctttcc ctgttagggc tgatggcggt tctttcctat    300
ctcattaccc gctaggggcc tgggagccct gtggctggat ctgagtgctc ctgagctggc    360
ttcactgcag aactctcagt ccctcatcag atcgagactc tatttccccc gtcagtctgg    420
gggcttcaca agggcaggag agccctccat cactgacttc cagatcagaa accctcagcc    480
aggcagcctt tgcccagaag gaacgtgctg gttgggatca ctgaagg                  527

<210> 439
<211> 629
<212> DNA
<213> Homo sapiens

<400> 439
ccgagtgcgg gggccgggtc tgtgcctttg ataaccgggc caccggccgg gagcaggaag     60
cccaggtgga gcagctgctg gggatggtcg agggcttggt gctggagcac aagggcgccc    120
attactccaa cgaggtgtat gagctggcgc aggtgctgcg ctgggcaggc cctgaggagc    180
ggctccggcg ggtggcggag cgcgtggcag ccagggtgca gaggaggcca tggggcgcct    240
ggctgtcggc ccggctgtgg aagtggctga agtcccccag gagctggagg ctgggcctgg    300
ccctgctgct ggggggcgcg ctcctgttct gggtgctgct ccacaggcgg tggtcggagg    360
ccgttgcgga ggtcgggcct gactgacagc gcaggtccta aaactgaagg caacttggtt    420
aagggaggct gaattcttgg agctgaaggg aaaacttcat tccaacggaa ggaatcctgt    480
artttcaggc atagttttaa tgacacagaa aactttgctg catcaccttt gcaactttgc    540
caaagctcag agttcacttt ttaagttttt aactcatttt aaatgatgtg tatgcagagt    600
tttaaaataa attcgtctaa caataaaaa                                      629

<210> 440
<211> 1412
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (778)
<223> n equals a,t,g, or c

<400> 440
ggcggcggac gcaggaggcc tcgtggagga cacagcagca tgggacagtc agggaggtcc     60
cggcaccaga agcgcgcccg cgcccaggcg cagctccgca acctcgaggc ctatgccgcg    120
aacccgcact cgttcgtgtt cacgcgaggc tgcacgggtc gcaacatccg gcagctcagc    180
ctggacgtgc ggcgggtcat ggagccgctc actgccagcc gtctgcaggt tcgtaagaag    240
aactcgctga aggactgcgt ggcagtggct gggcccctcg gggtcacaca ctttctgatc    300
ctgagcaaaa cagagaccaa tgtctacttt aagctgatgc gcctcccagg aggccccacc    360
ttgaccttcc aggtcaagaa gtactcgctg gtgcgtgatg tggtctcctc actgcgccgg    420
caccgcatgc acgagcagca gtttgcccac ccacccctcc tggtactcaa cagctttggc    480
ccccatggta tgcatgtgaa gctcatggcc accatgttcc agaacctgtt cccctccatc    540
aacgtgcaca aggtgaacct gaacaccatc aagcgctgcc tcctcatcga ctacaacccc    600
gactcccagg agctggactt ccgccactat agcatcaaag ttgttcctgt gggcgcgagt    660
cgcgggatga agaagctgct ycaggagaag ttccccaaca tgagccgctg caggacatca    720
gcgagctgct ggccamgggm gcggggctgt cggagagcga ggcagagcyg acggcgancc    780
acaacatcac agagctgcct caggctgtcg ctggccgtgg caamatgcgg gcccagcaga    840
gtgcagtgcg gctcaccgag atcggcccgc ggatgacact gcagctcatc aaggtccagg    900
agggcgtcgg ggagggcaaa gtgatgttcc acagttttgt gagcaagacg gaggaggagc    960
tgcaggccat cctggaagcc aaggagaaga agctgcggct gaaggcgcaa agggcaggcc   1020
cagcaggccc agaatgtgca gcgcaagcag gagcagcggg aggcccacag aaagaagagc   1080
ctggagggca tgaagaaggc acgggtcggg ggtagtgatg aagaggcctc tgggatccct   1140
tcaaggacgg cgaagcctgg agttgggtga ggacgatgat gaacaggaag atgatgmcat   1200
cgagtattty tgccaggcgg tgggcgaggc gcccagtgag gacctgttcc ccgaggccaa   1260
gcagaaacgg cttgccaagc cgcactggag cagcggctgg attgaacgcc ccagattggg   1320
gcccgagatg tggccctcgg tttcctttca taaaggagtt gtgtccccag cccttccact   1380
ccagtaaaaa actgcattgg caaaaaaaaa aa                                 1412

<210> 441
<211> 974
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (935)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (971)
<223> n equals a,t,g, or c

<400> 441
gagcaggcag agagatgagg aaactgagac ccagaaaggt ggaagcactt gtytaaggtc     60
acgcctccag gaagcagtgt gtccacgact ccagtccaag tggtcaggct ccagagccca    120
cagtcccagg ggtccatgat gccgagctgc aatcgttcct gcagctgcag ccgcggcccc    180
agcgtggagg atggcaagtg gtatggggtc cgctcctacc tgcacctctt ctatgaggac    240
tgtgcaggca ctgctstcag cgacgaccct gagggacctc cggtcctgtg cccccgccgg    300
ccctggccct cactgtgttg gaagatcagc ctgtcctcgg ggaccctgct tctgctgctg    360
ggtgtggcgg ctctgaccac tggctatgca gtgcccccca agctggaggg catcggtgag    420
ggtgagttcc tggtgttgga tcagcgggca gccgactaca accaggccct gggcacctgt    480
cgcctggcag gcacagcgct ctgtgtggca gctggagttc tgctcgccat ctgcctcttc    540
tgggccatga taggctggct gagccaggac accaaggcag agcccttgga ccccgaagcc    600
gacagccack tggaggtctt cggggatgag ccagagcagc agttgtcacc cattttccgc    660
aatgccagtg gccagtcatg gttctcgcca cccgcmagcc cctttgggca atcttctgtg    720
cagactatcc agcccaagag ggactcctga gctgcccaca tggcctaaga tgtgggtcct    780
ggatccttcc cccttctcac cataaccccc tctcagtgtt tccccaactt ctccctttta    840
gcagggtccc tttagagccc aactccaggt caaatctgga gctcaaatcc cagtgctccc    900
taacccttac cttcagtctc caccagcctg aaggncttcc taggggatcc tcaggcggcc    960
cccaccaggg naca                                                      974

<210> 442
<211> 1723
<212> DNA
<213> Homo sapiens

<400> 442
agcagcactt ccggtacgaa aaactcgctg ctgccccaac ctggcttgac aggcttggtc     60
tctgcaagtg gctctcagcc ccttcttctt tcctgcctca ccttccaatt cgtttgccgc    120
cgccgtcccg cagctgctgt ttccggagtt gccccttccc catgttccgg ggcaggagtc    180
cgcaaagcga agatccgccc gccggttcct catcatgtcc gaactgacta aagagctgat    240
ggagctggtg tggggcacca agagcagccc cggtctctcg gacaccattt tctgccgctg    300
gacgcaaggg tttgtgttta gtgaatcaga gggatctgca ttagaacagt ttgaaggtgg    360
cccctgtgct gttattgcac ctgttcaggc atttcttttg aagaagctcc tgttttcttc    420
ggagaagtct tcttggcggg attgttcaga ggaagagcag aaggaactcc tttgtcatac    480
cttgtgtgat attttagaaa gtgcttgttg tgaccactct ggatcatact gcttggtttc    540
atggttaaga ggaaagacaa ctgaggaaac tgctagtatt tctgggagtc ctgcagagtc    600
tagttgccaa gtggaacatt cttctgcctt ggctgtcgaa gagcttggct ttgagcgatt    660
tcatgcatta attcaaaaaa gatcgttcag aagtttacca gaattaaaag atgctgtctt    720
ggaccagtat tcaatgtggg gaaataaatt tggagtattg ctttttctgt attctgtatt    780
actgacaaag ggcattgaaa acataaaaaa cgaaattgaa gatgcaagtg aacccttgat    840
agatcctgta tatggacatg gcagccaaag tttaattaat ctcctgctga cgggacatgc    900
tgtttctaat gtatgggatg gtgatagaga gtgctcagga atgaaacttc ttggtataca    960
tgaacaagca gcagtaggat ttttaacact aatggaagct ttaagatact gtaaggttgg   1020
ttcttacttg aaatctccaa aattccctat ttggattgtt ggcagtgaga ctcacctcac   1080
cgtatttttt gccaaggata tggctttagt tgcccctgaa gctccttcag aacaagccag   1140
aagagttttt caaacctacg acccagaaga taatggattc atacccgatt cacttctgga   1200
agatgtgatg aaagcattgg accttgtttc agatcctgaa tatataaatc tcatgaagaa   1260
taaattagat ccagaaggat taggaatcat attattgggc ccatttcttc aagaattttt   1320
tcctgatcag ggctccagtg gtccagaatc ttttactgtc taccactaca atggattgaa   1380
gcagtcaaat tataatgaaa aggtcatgta cgtagaaggg actgcagttg tgatgggttt   1440
tgaagatccc atgctacaga cagatgacac tcctattaaa cgctgtctgc aaaccaaatg   1500
gccatacatt gagttactct ggaccacaga tcgctctcct tcactaaatt aatttgtcta   1560
agtatttata aggaagatct taataacaga tgttgaaaga aggagtcaag actggcaatt   1620
ggctggatta agctaaacac tggtatcact gattaactgt aaataacaat taaaaacaca   1680
ttttcagtgt taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                     1723

<210> 443
<211> 1258
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (528)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (726)
<223> n equals a,t,g, or c

<400> 443
gccaggtgct gggggcgact cggacagcgg gacgtngggg tggagtagga tggagtctcc     60
ctcccgagct gggggtgtgg gcctaggaaa ggctgcttcg ccgctgtgtt cggagagctc    120
tggatactgc ggggcttttc cgcggaggag cgcccgccgg taggttggcc ccgaaccgtg    180
ggggcggcga cggccgagtg ccaatttgac tctgtgcacc aaggtccccg cgccccggaa    240
cgggcgacgc cgcgccccca tcagagccgc rggcatctgc atctgggacc gacctcctgg    300
gctggctgat caaagaggaa gcagcagcaa tgtctgctgt ggggrctgca actccatacc    360
tgcatcatcc tggtgatagt cacagtggcc gagtgagttt cttgggggcc cagcttcctc    420
cagaggtggc agcaatggcc cggctactag gggacctaga cakgagcacg ttcagaaagt    480
tgctgaagtt tgtggtcagc agcctgcagg gggaggactg ccgagagntg ctgcagcgtc    540
ttggggtcag cgccaacctg ccggaggagc agctgggtgc cctgctggca ggcatgcaca    600
cactgctcca gcaggccctc cgtctgcccc ccaccagcct gaagcctgac accttcaggg    660
accagctcca ggagctctgc atcccccaag acctggtcgg ggacttggcc agcgtggtat    720
ttgggnagcc agcggccctc cttgattctg tggcccagca gcagggggcc tggctgccgc    780
atgttgctga ctttcggtgg cgggtggatg tagcaatctc caccagtgcc ctggctcgct    840
ccctgcagcc gagcgtcctg atgcagctga agctttcaga tgggtcagca taccgctttg    900
aggtccccac agccaagttc caggagctgc ggtacagcgt ggccctggtc ctaaaggaga    960
tggcagatct ggagaagagg tgtgagcgca gactgcagga ctgacccctc acttgaccag   1020
tcccattcag atccggcttg gacaggcacc tgagatggtg ccaaagtgca gctgactctt   1080
cccacgacag ccctgccctt cccatgaggc aggctcttca gtgagtgttt gaacgtaatt   1140
atgtagtttt ctgtttaatt gaaaaagaga gctatgcctt tttttctttt tggaagtaaa   1200
gcagctaaaa acawraaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa     1258

<210> 444
<211> 1248
<212> DNA
<213> Homo sapiens

<400> 444
gcagacttaa tgtcaagaat gaaaaaaaaa tagttcatca ggatgtaacc tgagattcac     60
ctctgcatct ttaccaaaag aatgcacgct tgaagaatgt ggaattcctg cttgtaaacc    120
gtatacactg tgggacgaga caccaatgtc ttggttacat caaaagaagg ctagcaatgt    180
gtgccagaag actcgggagg accagggaag cagtgaaaat gatgagagat ttaatgaagg    240
agttccccct tctgagtatg ttcaatatcc atgaaaacct tttagaagcc cttctggaac    300
tacaagcata tgctgatgtt caggcagtct tagcaaagta tgatgatata agcttaccaa    360
agtcagcaac aatatgctac acagctgctt tgctcaaagc aagagctgtc tctgacaaat    420
tctctyctga ggctgcatct cggcgggggc tgagcacagc agagatgaat gcagtagagg    480
ccattcatag agctgtggaa ttcaatcctc atgtgccaaa atacctacta gaaatgaaaa    540
gcttaatcct acccccagaa catatyctga agagaggrga cagkgaagca atagcatatg    600
cattctttca tcttgcacac tggaagagag tggaaggggc tttgaatctt ttgcattgta    660
cgtgggaagg cacttttcgg atgatccctt atcccttgga aaaggggcac ctattttatc    720
cttacccaat ctgtacagaa acagcagacc gagagctgct tccatctttc catgaagtct    780
cagtttaccc aaagaaggag cttcccttct ttattctctt tactgctgga ttatgttcct    840
tcacagccat gctggccctc ctgacacatc agttcccgga acttatgggg gtcttcgcaa    900
aagctttcct cagcactttg tttgccccct taaactttgt catggagaaa gtggagagca    960
tcctcccatc cagtctgtgg caccagctaa cacggatctg agagaagccc tgtcctccac   1020
tcacctcacc cgccgctgcc accatctcct ctgtgccaac tccttgtgga ccgcaagaaa   1080
gcatgacttt gaaaaaggga agccattccg agattttaaa atgttcatgg actattccat   1140
attaaaagct gtttttgttg tacaaaattc actgatgttc agttctattt tattttgcct   1200
tcagaaaaga agaaagtcaa aaataaaact tttgtgtatt acagcaaa                1248

<210> 445
<211> 932
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (864)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (880)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (911)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (912)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (921)
<223> n equals a,t,g, or c

<400> 445
ctggcaggtc ccagaaggtg gcgagtttcg cggccagagg cttacaggtc caggtggaga     60
ggccgggctg gccagggctt cggcctccgg cgtcgggaaa tggcggcggg gggcaggatg    120
gaggacggtt ccttggatat cacccagagt attgaagacg acccacttct ggatgcccag    180
cttctcccac accactcatt acaagctcac tttagacccc gattccatcc tcttcctaca    240
gtcatcatag tgaatcttct gtggtttatt catctcgtgt ttgttgtttt agcattttta    300
acaggtgtgc tttgttctta tcctaatcca aatgaggaca agtgcccagg aaattacaca    360
aacccattga aagttcagac ggttataatc cttgggaaag ttattttgtg gattctccat    420
ttactccttg aatgctacat ccagtatyac cacagsaaaa tcagaaaccg aggstataac    480
ttgatctacc gatcaacaag gcatctcaag agacttgcgt tgatgataca gtcctctggc    540
aacacagtgc ttctcctcat actgtgcatg cagcactcct tcccagagcc tggcagattg    600
tatcttgacc tcattctggc catcttggca ctggaactca tctgttccct gatatgtctc    660
ctcatttaca cagtgaaaat cccggagatt taataaagct aaaccagagc ctgatatact    720
tgaagaagaa aaaatctatg cttaccccag caatattacc ttcgggagac tgggattcag    780
aactattttc aagcctagaa agaaaattgg tgaaaaagca agggagacac cattgaatac    840
cttgaaggcg acacaatgcg ctgntgaagt aagcgaatgn tggctcttac tttcctcaga    900
ccttgggctg nnaagccagt ngaacgtgaa ga                                  932

<210> 446
<211> 2143
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1602)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2086)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2097)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2140)
<223> n equals a,t,g, or c

<400> 446
cgtccgcgga cgcgtgggcg gacgcgtggg cgagctgcag atgaagtttt agcagaagca     60
aagaaaccac gaattgagga tgaagagtgt gtgcgccttg ataaagagag attggctgcc    120
cgtttggagg gtcacaaaga agggattgta cagactgaac agattaggtc tttgtctgaa    180
gctatgtcag tggaaaaaat tgctgcaatc aaagccaaaa ttatggctaa gaaaagatct    240
actatcaaga ctgatctaga tgatgacata actgccctta aacagaggag ttttgtggat    300
gctgaggtag atgtgacccg agatattgtc agcagagaga gagtatggag gacacgaaca    360
actatcttac aaagcacagg aaagaatttt tccaagaaca tttttgcaat tyttcaatct    420
gtaaaagcca gagaagaagg gcgtgcacct gaacagcgac ctgccccaaa tgcagcacct    480
gtggatccca ctttgcgcac caaacagcct atcccagctg cctataacag atacgatcag    540
gaaagattca aaggaaaaga agaaacggaa ggcttcaaaa ttgacactat ggggaacyta    600
ccatggtatg acactgraat ctgtaacgga gggtgcatct gcccggaaga ctcagactcc    660
tgcagcccag ccagtaccaa gaccagtttc tcaagcwaga cctcccccaa atcagaagaa    720
aggatctcga acacccatta tcataattcc tgcagctacc acctctttaa taaccatgct    780
taatgcaaaa gaccttctac aggacctgaa atttgtccca tcagatgaaa agaagaaaca    840
aggttgtcaa cgagaaaatg aaactctaat acaaagaaga aaagaccaga tgcaaccagg    900
gggcactgca attagtgtta cagtacctta tagagtagta gaccagcccc ttaaacttat    960
gcctcaagac tgggaccgcg ttgtagccgt ttttgtgcag ggtcctgcat ggcagttcaa   1020
aggttggcca tggcttttgc ctgatggatc accagttgat atatttgcta aaattaaagc   1080
cttccatctg aagtatgatg aagttcgtct ggatccaaat gttcagaaat gggatgtaac   1140
agtattagaa ctcagctatc acaaacgtca tttggataga ccagtgttct tacggttttg   1200
ggaaacattg gacaggtaca tggtaaagca taaatcgcac ttgagattct gaattatttg   1260
gctcctccat ttctggaaat tgagactcaa gctttatgaa tttatcaaga acttaaaaat   1320
gaagaaggtc acagattgat cttttataag accttatttg atgctttgtg cttcaaggag   1380
atgatacctg tcatccatat aagcaaactt tttggcttac aactattttt ttaatattag   1440
ccttctagtc tgtaatggaa attgtatatt ttgatagaag ttttttctcc attggttaaa   1500
ttagcattac ttaaaatttg tttctttaga aaataaatgc aggttataaa tgtgtgtata   1560
tttagagatt ataaggctct ctgagccatc ttctgatttt tncattgctc tataattctt   1620
tttactgaaa atactatgtt atgaatggta ttaaatttta gtctctggaa catccaaaac   1680
caagcaaagg gatgtgacta ttttgaatga atcagaatgt caacttgtat gtacactata   1740
tctacactta ctcattattt aaaaagaata atgaaaaatc tagatcaatt cttcaatttg   1800
attgaactgt tcagcctttt caagatttct ttatttacaa atgattacat ttaaatgaat   1860
gtacattctt ctcactgact ttggtgattt tgaaacctag aatgatgtgt ttctatctgt   1920
aatatctttc catttgaaaa aaatctcaaa acacagatta aaaccacaat aggctgtagt   1980
attttttatt ttgggagcca gagtatgatt tgggggaaga atatgtatca gccctattgc   2040
agtataactt taagctcctt ttctctttag tccacttttg attggnaatt ttatggnata   2100
ggatttgaat ctcccattta aggctggcag cctggagtcn tac                     2143

<210> 447
<211> 2069
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2046)
<223> n equals a,t,g, or c

<400> 447
gcgccgactg agcctctaaa gcgacttcag ctctgcccca ccaacaccac cgctccgggg     60
gaggggctta atgctgggga agggatgtct taaaagagga gaagctttaa attagacgat    120
cggagaaggc tgagggaatt gctatgaarg ggcgggagct gaagtgtaga ggactccttt    180
agacagcaga aagggaaagc cgttgagaag ttcccttcaa actccacctg cctcctctcc    240
aattcaaact ccactccctt ctccaaaagt taaaaggaaa gccaagtttg ccacgctccc    300
ctgttcctac tcaataaata cttcttctac tccgccaccg ggaaaacaga aaaaaaaaac    360
taatttcctt cccaatatta ggacttagaa aagctctagg tcccgcaayt tgaattttag    420
cctaggggaa tcaaaatagt aggagcatta ctcttgtttc ctttttcaaa atcccacacc    480
tcatccttcc tgcgacgcca tgtctaccaa catttgtagt ttcaaggaca ggtgcgtgtc    540
catcctgtgt tgcaaattct gtaaacaagt gctcagctct aggggaatga aggctgtttt    600
gctggctgat actgaaatag accttttctc tacagacatc cctcctacca acgcagtgga    660
cttcactgga agatgctatt tcaccaaaat ctgcaaatgt aaactgaagg acatcgcatg    720
tttaaaatgt gggaacattg tagkttatca tgtgattgtt ccatgtagtt cctgtcttct    780
ttcctgcaac aacrgacact tctggatgtt tcacagccag gcagtttatg atattaacag    840
actagactcc acaggtgtaa acgtcctact tyggggcaac ttgccagaga tagaagagag    900
tacagatgaa gatgtgttaa atatctcagc agaggagtgt attagataaa tggaattatg    960
atatatatga tatacaaact tttttctatt taaaaatata ttaatggatc aactttaaaa   1020
ttgttagttg ccagtgatct tttttggaaa acaaaaatgg ggcatttgtt gatttattta   1080
ttttctgtct ctaattagtt acctcagttt gattgaagcc agtggagttg tgcttttcct   1140
ctacttctac ttcctctccc ccaccttttt ctgcccagtg taggtgtatt cttaaattca   1200
gacgggaaga ttctttcaca tatcactcag ttacctccca atctggggga gtttttctta   1260
caacttgata ccagatacca ttaattttac attcctgaat aaaggcctag tacccacgca   1320
tatttcaacc atgcatatat caagttcaac ygagttttaa taggggatta aaaaaacaag   1380
ctgttaggtt tccatgggca ctggttctca taggttctat tggtgataac tgctttaaca   1440
tggagcaaga gtttgtgaat caggaaatag aataaattaa aatttaaaat atatagagga   1500
atcctcttga ttgctcagca tgatgttaga taaatgagtt tgtcagaaaa tatcagtata   1560
cgctgtttac caatgttatt tatttacatt cttctaaagc cattatggat attgtattat   1620
gagagctaaa cctaaataag ttatcctgtt ccctaggacc ttctctgtaa atagtgaatt   1680
ttagacgagt agtctgtcct aaatcttaaa tagaaaaaaa aactaaagcg atttgcttaa   1740
gccattgtac attataaaga gctgttttgt tttgctttgc tttgctttgt tttgtttttt   1800
taaagctgca ttcagagcca caaaggaata ggaaagtagg gtagtgttgg attctggttt   1860
tatgtaactc taaaataaat gtatctcttt aatatctcag ttgtagggat tttgtcaata   1920
ccaaagcaga ctgagttgtg gttttgtaaa taaagttttt tctaaaaatg accattcttc   1980
ctttaatttt ttgttatgcc cacatattgt atgtaaaaat ataaataaat agtacttaaa   2040
gtatanaaaa aaaaaaaaaa aaaaaggtt                                     2069

<210> 448
<211> 626
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (238)
<223> n equals a,t,g, or c

<400> 448
gcagagggcc tgtagctggg ggcatgctgc aggtgctggt gtggcatcaa gccttaggga     60
cctcaacttg agtccccagc aacaataatg aggctgaatg gggccagaaa tcaaggtatg    120
ccatggctga gatgaaccac catgtatgcc ctgtggagaa ctggtcctac aacgagtcct    180
gccctcctga ccctgctgag caagggggtc ccaagacctg ctgcaccctg gacgatgncc    240
ccctcatcag caagtgtggc tcctatcccc cagaaagctg cctcttcagc ctcattggca    300
acatgggtgc tttcatggag gccctgatct gcctcctgcg ctacgggcag ctcctggagc    360
agagtcggca ctcttgggtt aacaccacgg yactcatcac aggctgcacc aacgctgcgg    420
gcctcttggw ggttggcaac tttcagcctc gttttaggtg gagtcttctt tgtccatgag    480
agttctcagc tgcaacatgg ggcagccctg tgtgagtggg tgtgtgtcat cgatatcctc    540
attttctatg gcaccttcag ctacgagttt ggggcagtct cctcagacac actggtggct    600
gcactgcact tagcccctgg gccggg                                         626

<210> 449
<211> 1480
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (103)
<223> n equals a,t,g, or c

<400> 449
ctgtttccat agtgtgaatg gcacctgttc ccatcaagcc caacaggagt aaggaacatg     60
caagttgtaa ctccacaata aaattaagaa acattttgtt ncnttataca aggttttact    120
tttacaaaag tatccctttt aaataagatg catctgatgt acaaagtatc aaacgtgttt    180
tttttttttt ttctcagctt gaaaagaggc tggaaatggg atgcaggtta ggttcaaagc    240
ttaaactttg taacaactgg acacaaggtt cctcagaatt gtcaaaagtc tcttgtgaca    300
catcctacaa ccttttctca ataaacaaca atatatgaaa taattaccaa aacatctcct    360
aattcatata atttacatga tataagcttg cttgatagca gctggtgttc agtcgtgaaa    420
aaacacacaa agtaaaatgg ttgctgacta caatgtacag ctattgctgg gtgtgatgga    480
atgtacaaac ggaggtcgat gtagacgagt tttttccacc agagatattg cctttccatg    540
cagcacttgt gctctcagct ttaacttggc ttttggttct tcctttatct tcagtatctg    600
ttctgatgct cataatgcca ccgattaaaa tctatattaa aagctacaat gctaccagaa    660
gccatgccag tgatcagagt cctctggtca tgggacaagt ccattgctct aatgccagca    720
tcacatccag ggtaaatgta cagttgcttg aagtcacagg cctgccagac ctctactacc    780
ccattgtccc ctccggtgac caggttctgg ccgtcactgc tcaggagaat ggcccgtgtt    840
gaatcattga tctccatttg agccaaaagt ttcccattaa tgctgaaatt actgaatcgc    900
cctcgttcat agtatatgat acagtggcct tcgctggaga cagatatcaa gcgtgggaat    960
aagcagtttt ctggtccttc aagggctctc agcaaatctc cagtgatggt gtggacaagg   1020
caagggccct ctttagcacc actgataaca agcccaagtt ctgcacagac agaaacacag   1080
acaacttcat ggtcatggcc tgtgaggacg gctcttggtg ccggatagtc actgctgtta   1140
gggttgtctc ctatgatatg gtgccgccca ctccagtacc agagcagcag ggtggcatct   1200
cgagatccgg acacgatgta gcagtcccca ccaatgtatg actcggacct ggccaagcaa   1260
gtgaccacat cccaatggcc aaatacaatc tgagtcaatt tccctgtttc tgtagaataa   1320
actctgaagc tcttatccca gaatccacag ataagaatat agcgattatc tgctgttacc   1380
acaaaacaat gtgcattgat ttgtatactc tggtcaacga ggtctgtgat ctgccgtttg   1440
tttacacctg aattattggc tattaatgga tccatttcaa                         1480

<210> 450
<211> 1417
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<400> 450
ggcagagctc ggcatcactc gcccagtgcc aaccaacact tgtgtcatct tgggcttggc     60
tggaggtgtt atcatttata tcatgaagca ctcgttgagc gtgggggagg tgatcgaagt    120
cctggaagtc cttctgatct tcgtttatct caacatgatc ctgctgtacc tgctgccccg    180
ctgcttcacc cctggtgagg cactgctggt attgggtggc attagctttg tcctcaacca    240
gctcatcaag cgctctctga cactggtgga aagtcagggg gacccagtgg acttcttcct    300
gctggtggtg gtagtaggga tggtactcat gggcattttc ttcagcactc tgtttgtctt    360
catggactca ggcacctggg cctcctccat cttcttccac ctcatgacct gtgtgctgag    420
ccttggtgtg gtcctaccct ggctgcaccg gstcatccgc agaatcccct gctctggctt    480
cttcagtttc tcttccagac agacacccgc atctacctcc tagcctattg gtctctgctg    540
gccaccttgg nctgcctggt ggtgctgtac cagaatgcca agcggtcatc ttccgagtcc    600
aagaagcacc aggcccccac catcgcccga aagtatttcc acctcattgt ggtagccacc    660
tacatcccag gtatcatctt tgaccggcca ctgctctatg tagccgccac tgtatgcctg    720
gcggtcttca tcttcctgga gtatgtgcgc tacttccgca tcaagccttt gggtcacact    780
ytacggagct tcctgtccct ttttctggat gaacgagaca gtggaccact cattctgaca    840
cacatctacc tgctcctggg catgtctctt cccatctggc tgatccccag accctgcaca    900
cagaagggta gcctgggagg agccagggcc ctcgtcccct atgccggtgt cctggctgtg    960
ggtgtgggtg atactgtggc ctccatcttc ggtagcacca tgggggagat ccgctggcct   1020
ggaaccmaaa agacttttga ggggaccatg acatctatat ttgcgcagat catttctgta   1080
gctctgatct taatctttga cagtggagtg gacctaaact acagttatgc ttggattttg   1140
gggtccatca gcactgtgtc cctcctggaa gcatacacta cacagataga caatctcctt   1200
ctgcctctct acctcctgat attgctgatg gcctagctgt tacagtgcag cagcagtgac   1260
ggaggaaaca gacatgggga gggtgaacag tccccacagc agacagctac ttgggcatga   1320
agagccaagg tgtgaaaagc agatttgatt tttcagttga ttcagattta aaataaaaag   1380
caaagctctc ctaaaaaaaa aaaaaaaaaa aactcga                            1417

<210> 451
<211> 2062
<212> DNA
<213> Homo sapiens

<400> 451
cccgactcta ggccggaagc gcgcggagac catgtagtga gaccctcgcg aggtctgaga     60
gtcactggag ctaccagaag catcatgggg ccctggggag agccagagct cctggtgtgg    120
cgccccgagg cggtagcttc agagcctcca gtgcctgtgg ggctggaggt gaagttgggg    180
gccctggtgc tgctgctggt gctcaccctc ctctgcagcc tggtgcccat ctgtgtgctg    240
cgccggccag gagctaacca tgaaggctca gcttcccgcc agaaagccct gagcctagta    300
agctgtttcg cggggggcgt ctttttggcc acttgtctcc tggacctgct gcctgactac    360
ctggctgcca tagatgaggc cctggcagcc ttgcacgtga cgctccagtt cccactgcaa    420
gagttcatcc tggccatggg cttcttcctg gtcctggtga tggagcagat cacactggct    480
tacaaggagc agtcagggcc gtcacctctg gaggaaacaa gggctctgct gggaacagtg    540
aatggtgggc cgcagcattg gcatgattgg gccaggggtc ccacaggcga gtggagcccc    600
agcaaccccc tcagccttgc gtgccctgtg tactggtgtt ctccctggcc ctccactccg    660
tgttcgaggg gctggcggta gggctgcagc gagaccgggc tcgggccatg gagctgtgcc    720
tggctttgct gctccacaag ggcatcctgg ctgtcagcct gtccctgcgg ctgttgcaga    780
gccaccttag ggcacaggtg gtggctggct gtgggatcct cttctcatgc atgacacctc    840
taggcatcgg gctgggtgca gctctggcag agtcggcagg acctctgcac cagctggccc    900
agtctgtgct agagggcatg gcagctggca cctttctcta tatcaccttt ctggaaatcc    960
tgccccagga gctggccagt tctgagcaaa ggatcctcaa ggtcattctg ctcctagcag   1020
gctttgccct gctcactggc ctgctcttca tccaaatcta gggggcttca agagaggggc   1080
aggggagatt gatgatcagg tgcccctgtt ctcccttccc tcccccagtt ggggggaata   1140
ggaaggaaag gggaagggaa atactgagga ccaaaaagtt ctctgggagc taaagataga   1200
gcctttgggg ctatctgact aatgagaggg aagtgggcag acaagaggct ggccccagtc   1260
ccaaggaaca agagatggtc aagtcgctag agacatatca ggggacatta ggattgggga   1320
agacacttga ctgctagaat cagaggttgg acactataca taaggacagg ctcacatggg   1380
aggctggagg tgggtaccca gctgctgtgg aacgggtatg gagaggtcat aaacctacaa   1440
tcagtgtcct gttggtccta gcccatttca gcaccctgcc acttggagtg gaccctccta   1500
ctcttcttag cgcctaccct catacctatc tccctcctcc catctcctag gggactggcg   1560
ccaaatggtc tctccctgcc aattttggta tcttctctgg cctctccagt cctgcttact   1620
cctctatttt aaagtgccaa acaaatcccc ttcctctttc tcaaagcaca gtaatgtggc   1680
actgagccct acccagcacc tcagtgaagg gggcctgctt gctctttatt ttggtcccgg   1740
atcctggggt ggggcagaaa tattttctgg gctggggtag gaggaaggtt gttgcagcca   1800
tctactgctg ctgtacccta ggaatatggg gacatggaca tggtgtccca tgcccagatg   1860
ataaacactg agctgccaaa acattttttt aaatacaccc gaggagccca agggggaagg   1920
gcaatgccta cccccagcgt tatttttggg gagggagggc tgtgcatagg gacatattct   1980
ttagaatcta ttttattaac tgacctgttt tgggacctgt tacccaaata aaagatgttt   2040
ctagaaaaaa aaaaaaaaaa aa                                            2062

<210> 452
<211> 1527
<212> DNA
<213> Homo sapiens

<400> 452
gtttgttttt ttcctttgtg gtgttttttc gtaaacagaa gttgttgatt ttaatgcagt     60
tcctcattaa tgctatacct tatatttact ctgtcttaaa gccacgttta gatggatagc    120
catctcattc ttgtagccaa gcatgtttat tgtaattttt cttccatctc tgaaataatt    180
tgcttgtcag actctatagg gattattcct ctgtatgtgg tactttaaaa aaaaaacttt    240
aaacatgtca aataatggaa aagattggag aaaatatcat aaggtgattc atacttaagg    300
ccatgwctta tagatagaat acatacttaa atttgattgg tgaaatattc tgcagctctt    360
ctaratggca ggtgatagta aatacacaaa aattgtggtt ctaccaatag catattcatt    420
ccttcyataa caaagcttat attaatgwga gaacagaaga tgaaattaaa acagacttta    480
ttatctctta aaaagccatg agacttaaca gaagttaaaa gcgtgttttt ttaattcagg    540
aagaggatca cctagcccgg gtaggaagag gcaatcaccc gtatgcttgt ktgtgccctg    600
aaaactgcag agaatccaca aaataccaga gcctggttaa accccactga ggttgaggaa    660
acgtcccatg cagtcaactg ttgctactta aatgcagctg tttctgcatt ttttgatcgc    720
tgcagaacat ctgaggtagt rgaaatccaa gcactgagaa cagatggaga gcacatgaaa    780
aaggaagaat taaatgtgtg caaccacatg gaggtgggcc aaacaggtag ccagaacttg    840
accacaggaa cagacaaacc ggagcagcaa gtccctttgg ccctgatctg gtccctgtag    900
cacagaggtc cgaagaaccg ccttcagaaa gaggaggcat atttggaagt gatgggaaag    960
actttgtgga caaggatgga gaacactttg gaaaattgca ttgtgccaag agacaacaaa   1020
taatgagcaa cagtgaaaat gcaattgagg aacagattgc ctcaaatact actacgactc   1080
ctcaaacatt catttctacg gatgacttgc tggactgctt ggtgaatcca caagtaacca   1140
ggatagtggc acaacttttg atacaaggaa gaagtttatg attcaagtgg aagatgactt   1200
ttaaaataat attttttaaa tatatatttt taagtagtat gactaaaata aagatgaacc   1260
agcaaaaggt cagtttgcac atttgtaaat gtatttatcc ttaccgaatt acatgtcagt   1320
ctgttgccac cttctttcat gcacattcct ctttggcaaa ctggctgctc tttgtttgta   1380
agsttttgtt cctctctcat cccatacttt tagcctgtgt caaatgtaag tcccaagtat   1440
ttccagcagg aagtaatgtc ttcctcagcc tcaaccaggg accaaccggc tgcttacttt   1500
tgcaaataaa attttactag aacacga                                       1527

<210> 453
<211> 763
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (632)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (654)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (669)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (677)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (695)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (750)
<223> n equals a,t,g, or c

<400> 453
gcagcaatag gatactgata catcctcata actcattccg agtctaaaca ttaaagataa     60
aagggaaata tgccactggc aatatctttt ctttcttatt cagacatttg attcttccag    120
tcttaatcct cgtcccacat gcctctggca catctacttg agcacattta ttctttatct    180
gattatccta ctccaatttc cataagcacc atcctattct tggcattaca cctcctctcc    240
aatattttac ccagttcttt tttgttgttg atgtttaaat acttcctcaa attctcctgc    300
ttattttgtc agtgtgaaac cagagtagta atctctaaaa gcctcttggg ctgctcttac    360
ttttttgact tatgttactc attgagcaag tattttcckg cttctctttt atctgttgtt    420
ttgtttacta gtttgtcagc atcaaatgtt ttctgtctta aatccaaagc tcactggtac    480
cacatacaaa gttcaataat gtattctgca aacctaacat attatcatgc tcatgtacaa    540
ttctgttgct ttcaatcatc agtccttata tatctgtcta gaaaacttca ttcacatcca    600
cttccattgg aatgactgaa tcccaagtcc gnaactctcg ctttctatcc tggncttcnt    660
taatcctgna aaggggntac agacatggat aaagncacca ttggcacctc aagaaggttt    720
acaaattggt aaggaaatgt aggaggatan ggacccaagg cag                      763

<210> 454
<211> 817
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (780)
<223> n equals a,t,g, or c

<400> 454
gcggacggtg ggcgcgccgc tcctgcgggt cggactgggg ctgtggcggg agagaagatg     60
ccgcagcccg agtcccagaa ggcggcgatc ctgggctgcg ggcaaggcgg aaattgacaa    120
tggcccttca gctatgctag gtctataatg ggaagtgtca cagttcggta tttctgttat    180
gggtgccttt ttacatctgc gacctggaca gttttgcttt ttgtttattt caacttcagt    240
gaagtgactc agccacttaa gaatgtgccc gtcaaggggt ctgggcccca cggaccatct    300
ccaaaaaaat tctatccccg tttcactcga ggcccaagtc gagtgctcga gccacagttc    360
aaagcaaaca aaattgacga tgtgatagac agtcgtgttg aagatccaga agaaggccac    420
ttgaaattct cttctgaatt agatgtaaag aaaagttcta cccacctgac ctgccagctg    480
ctagtgttgt tatctgtttc tataatgaag cgttttctgc cttgcttcgg acagtgcaca    540
gtgtcataga ccgcacgcca gcacacctgc ttcatgaraw catccttgtg gatgatgata    600
gtgactttga tgatttgaaa ggagaactag atgaatatgt ccaaaaatac ctccctggaa    660
aaattaaagt cataagraat acaaagcgtg aggggttgat tcgaggggag aatgattggc    720
aatatcagtg agcgtgtgga actgagaaag aagttgggct gtaaatcatt taaatggtan    780
gtgggtaatg tatacccaga gatgcagaaa tctgggt                             817

<210> 455
<211> 539
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (501)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (504)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (537)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<400> 455
ctcaaggcca tggattccaa cgggttgagc gatccctacg tgaagttccg gcttgggcat     60
cagaagtaca agagcaagat tatgccaaaa acgttgaatc ctcagtggag ggaacaattt    120
gattttcacc tttatgaaga aagaggagga gtcattgata tcactgcatg ggacaaagat    180
gctgggaaaa gggatgattt cattggcagg tgccaggtcg acctgtcagc cctcagtagg    240
gaacagacgc acaagctgga gttgcagctg gaagagggtg agggacacct ggtgctgctg    300
gtcactctga cagcatcagc cacagtcagc atctctgacc tgtctgtcaa ctccctggag    360
gaccagaagg aacgagagga gatattaaag agatatagcc cattgaggat atttcacaac    420
ctgaaagatg tgggatttct ccagtgaaag tcatcagagc ggaagggtta atggctgccg    480
acgtcactgg taagagatga ngcnaatctc ctaatgctcc agatcaagca gcacacnan     539

<210> 456
<211> 661
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (642)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (657)
<223> n equals a,t,g, or c

<400> 456
ggccgccgcc gggactagaa gtgagccgcc cgggtcccaa acgccagcca gccagtcagt     60
gggtcccgca gtcgcccgca accggggcga atcatggcgg ccgccaaggt ggctttaacc    120
aagagagcag atccagctga gcttagaaca atatttttga agtatgcaag cattgagaaa    180
aacggtgaat ttttcatgtc ccccaatgac tttgtcactc gatacttgaa catttttgga    240
gaaagccagc ctaatccaaa gactgtggaa cttttaagtg gagtggtgga tcagaccaaa    300
gatggattaa tatcttttca agaatttgtt gcctttgaat ctgtcctgtg tgcccctgat    360
gctttgttta tggtagcctt tcagctgttt gacaaagctg gcaaaggaga agtaactttt    420
gaggatgtta agcaagtttt tggacagacc acaattcatc aacatattcc atttaactgg    480
gattcagaat ttgtgcaact acattttgga aaagaaagaa aaagacacct gacatatgcg    540
gaatttactc agtttttatt tggaaatcca ctggagcacg ccaagcaagc ctttgtgcac    600
ngggccatgc taggactggg agggtncagc catcgattcc gngcatctgg cacatcngcc    660
c                                                                    661

<210> 457
<211> 1689
<212> DNA
<213> Homo sapiens

<400> 457
tttttttttt gaaatgaaat gaaaacgtaa gcatttaata gtggttttaa aaatcagtaa     60
cttttgttca tctgtgtttt ctttttagaa tgaagtgatg gaggctggtc tctgtctgaa    120
agcagtgctc taccaagtcc tggagatgaa gggaattcac tctgttttgc agaaaagatt    180
ctgtggatta atacagaagc accagcaaca ccagaggggt ggagactcct ttctctcccg    240
attctacagt ctggctctaa gcccagtaaa acagctcccg agcactgctt cagctgggtc    300
cagtcttgac aaaggcagga agccagctag ggtgggggcg atagggtcag cgggtatgtc    360
ccactgttgg aggtcactgg tattctgttt gtttttgttt tgtttcgttt tgttttttga    420
gacagggtct cgttctgtcg cttagctgga gtgcggtggc gtgatcatgg cactgctatt    480
cttgaagcac tccacccacc tgggctactt tttctttagt gcagaggtgc actgtcttct    540
tttaagtggg atcgcgtaac atgagctggt agagcacgga gaggcaggca gccaggttac    600
gaagactaag ccaattattc actgaagtca tcctcctctc ccccaccatt cgatttgatc    660
tacctctaag ccaggctgtg aagaaaagga aggcacttta gaagacctca gcagtgtggt    720
tctgtgtcta cttccatgac ctgtacctga gtatcttagc cagccagcct taggaacacc    780
accaaggtta ctttgaaatc tatgtatata gctagttaca gacgggagct atgtgtttct    840
tcattatttt gcagctcctc gttgttcctg tgattcctga acaccttttt ggaaatatgg    900
gtctctgtga gttttgagca cactactatc actttggata gtcactccat ttatattttt    960
ataaacttcc attagagaat cattaaggct gtttaatatc tgctctggat attacgcatt   1020
ggctttttgt tgcctagtgc tacaaacctt cctgtgggac tcagtgtctt caggcaatga   1080
ttgtgtatcc tgttacagat ggttgtgata caagaagaac cactcttctt tgaaaataaa   1140
ctcttggaag cttttgccag ctatctgggg ggtaggagga atattagcaa ctgtattggt   1200
tgtctacaga tacagaattg cctgttgtga gggaactgat tgttttgttg ggaaaagaaa   1260
tttaccagga gaaagagttt tgtgctgtat tgtgagagat ctcgcctctc agttaaatga   1320
gccctgggtt aaagtcagtg tgaagggcag ctgtgtgcgg gcacgagcca gagtgtctgc   1380
ctcagactag atttgacttg agttctttat gacccaggac tctggataat gtgaatttgc   1440
tttcctattt aactagaaga tacatgtact atagatcatt gtctcatttt agtgattgtt   1500
ccttaaacta gtgaaactag tggatttctc ttcttcctct ttattttttg catgttaaat   1560
gtgaacctta gtgtatttgt attttgtaga aaataatgaa aaattttaat ggagaatgat   1620
ttaaaaacat ttacaataca ttatttttgc atctgtaaaa aaaaaaaaaa aaaaaaaaag   1680
ggcggccgc                                                           1689

<210> 458
<211> 1279
<212> DNA
<213> Homo sapiens

<400> 458
cataagtgat ttactagttg gcatattctg catgcctata acactgctgg acaatattat     60
agcaggatgg ccatttggaa acacgatgtg caagatcagt ggattggtcc agggaatatc    120
tgtcgcagct tcagtcttta cgttagttgc aattgctgta gataggttcc agtgtgtggt    180
ctaccctttt aaaccaaagc tcactatcaa gacagcgttt gtcattatta tgatcatctg    240
ggtcctagcc atcaccatta tgtctccatc tgcagtaatg ttacatgtgc aagaagaaaa    300
atattaccga gtgagactca actcccagaa taaaaccagt ccagtctact ggtgccggga    360
agactggcca aatcaggaaa tgaggaagat ctacaccact gtgctgtttg ccaacatcta    420
cctggctccc ctctccctca ttgtcatcat gtatggaagg attggaattt cactcttcag    480
ggctgcagtt cctcacacag gcaggaagaa ccaggagcag tggcacgtgg tgtccaggaa    540
gaagcagaag atcattaaga tgctcctgat tgtggccctg ctttttattc tctcatggct    600
gcccctgtgg actctaatga tgctctcaga ctacgctgac ctttctccaa atgaactgca    660
gatcatcaac atctacatct acccttttgc acactggctg gcattcggca acagcagtgt    720
caatcccatc atttatggtt tcttcaacga gaatttccgc cgtggtttcc aagaagcttt    780
ccagctccag ctctgccaaa aaagagcaaa gcctatggaa gcttatgccc taaaagctaa    840
aagccatgtg ctcataaaca catctaatca gcttgtccag gaatctacat ttcaaaaccc    900
tcatggggaa accttgcttt ataggaaaag tgctgaaaaa ccccaacagg aattagtgat    960
ggaagaatta aaagaaacta ctaacagcag tgagatttaa aaagagctag tgtgataatc   1020
ctaactctac tacgcattat atatttaaat ccattgcttt ttgtggcttt gcacttcaaa   1080
tttttcaaag aatgttctaa ataaaacatt tactgaaagc cctctctggc aaaaaaatta   1140
aaaataaaca aaaatggtca taagatcata aacaatctta tgttgtataa aaatacgtag   1200
agtgacttag acatgtttgc atgaataaat atatttctag agaacagtta aaaaaaaaaa   1260
aaaaaaaaaa aaaaaaaaa                                                1279

<210> 459
<211> 2046
<212> DNA
<213> Homo sapiens

<400> 459
tgatttggaa accagaggaa aggcgctgtt ttcaccgaat tagaatcgcg ggaaaataga     60
gaagagtttg tttgaaggtc tcgcgagatc gagtgagtac ggctcgccaa gttggagcgc    120
tctcggatta gacacagcaa ctattcagct gcgaggggac gggagaggtg gtgagcactc    180
tcgcgagatt tgaaggagcg gcggaggcca gagggaggag aggtttgtaa actaggaggc    240
tccgggtttc cgggcacttt tattaggtcg tcttctgggc caccagtgcc ccttccatct    300
ccacaggcag tccctccatc gctaaccttt ttttaaccgg ccttttagga ccggaagtcc    360
ttcatctcaa gcatccaatg ctgaaagcgg cctgattttc tctaccggaa gcccttttcc    420
agaggctggg aacacggccc acctagcagg aagtcccacc tccttgagct ccgccaccct    480
tcccgaagtt tttctgtcac ctgtgttagg ctccgtcccc tttccgcgtt ttatccccgt    540
accagaaaag gatacattta gtgcctccca cccagctcca ctaaacgggt tggatatctc    600
attctttgag ttggtgttcc ttccccggcg cccccatgta gctgggaagt gggacctggg    660
ggtggttgga cccctgggat cctaaaggag gggcagggag ggcgcagaac tccgcttctg    720
ctccttgcta ccaggacgcg cggcctcctc agcctctttc ctcccgctgc catgcaccct    780
gcagccttcc cgcttcctgt ggttgtggcc gctgtgctgt ggggagcggc cccgacccgg    840
gggctcattc gagcgacctc ggaccacaat gccagcatgg actttgcaga ccttccagct    900
ctgtttgggg ctaccttgag ccaggagggc ctccaggggt tccttgtgga ggctcaccca    960
gacaatgcct gcagccccat tgccccacca cccccagccc cggtcaatgg gtcagtcttt   1020
attgcgctgc ttcgaagatt cgactgcaac tttgacctca aagtcctaaa tgcccagaag   1080
ctggatatgg tgccgctgta gtacacaatg tgaattccaa tgaacttctg aacatggtgt   1140
ggaatagtga ggaaatccag cagcagatct ggatcccgtc tgtatttatt ggggagagaa   1200
gctccgagta cctgcgtgcc ctctttgtct acgagaaggg ggctcgggtg cttctggttc   1260
cagacaatac cttccccttg ggctattacc tcatcccttt cacagggatt gtgggactgc   1320
tggttttggc catgggagca gtaatgatag ctcgttgtat ccagcaccgg aaacggctcc   1380
agcggaatcg acttaccaaa gagcaactga aacagattcc tacacatgac tatcagaagg   1440
gagaccagta tgatgtctgt gccatttgcc tggatgaata tgaggatggg gacaagctgc   1500
gggtactccc ctgtgctcat gcctaccaca gccgctgcgt ggacccctgg ctcactcaga   1560
cccggaagac ctgccccatt tgcaagcagc ctgttcatcg gggtcctggg gacgaagacc   1620
aagaggaaga aactcaaggg caagaggagg gtgatgaagg ggagccaagg gaccaccctg   1680
cctcagaaag gaccccactt ttgggttcta gccccactct tcccacctcc tttggttcct   1740
tagccccagc tccccttgtt tttcctgggc cttcaacaga tcccccactg tcccctccct   1800
cttcccctgt tatcctggtc taataacccc ccacacatac acctctggtg acctatttgc   1860
acagaccgtc gtcttccctc cagtcttctg agggataggg gacattccat cccaagcttc   1920
tcccttaccc acacctatcc ttttgagggg ctttggggtg gagctggggc aagcagaggg   1980
actgggtctt cacttcttgg gctaataaaa ttgtttcttt gtggactaaa aaaaaaaaaa   2040
aaaaaa                                                              2046

<210> 460
<211> 716
<212> DNA
<213> Homo sapiens

<400> 460
ggcacgagcg ctgtcctggc tgccgccacc cgaacagcct gtcctggtgc cccggctccc     60
tgccccgcgc ccagtcatga ccctgcgccc ctcactcctc ccgctccatc tgctgctgct    120
gctgctgctc agtgcggcgg tgtgccgggc tgaggctggg ctcgaaaccg aaagtcccgt    180
ccggaccctc caagtggaga ccctggtgga gcccccagaa ccatgtgccg agcccgctgc    240
ttttggagac acgcttcaca tacactacac gggaagcttg gtagatggac gtattattga    300
cacctccctg accagagacc ctctggttat agaacttggc caaaagcagg tgattccagg    360
tctggagcag agtcttctcg acatgtgtgt gggagagaag cgaagggcaa tcattccttc    420
tcacttggcc tatggaaaac ggggatttcc accatctgtc ccagcggatg cagtggtgca    480
gtatgacgtg gagctgattg cactaatccg agccaactac tggctaaagc tggtgaaggg    540
cattttgcct ctggtaggga tggccatggt gccagccctc ctgggcctca ttgggtatca    600
cctatacaga aaggccaata gacccaaagt ctccaaaaag aagctcaagg aagagaaacg    660
aaacaagagc aaaaagaaat aataaataat aaattttaaa aaaaaaaaaa aaaaaa        716

<210> 461
<211> 911
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (782)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (851)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (869)
<223> n equals a,t,g, or c

<400> 461
gtgatcagca taccggtcaa gtcctacccc cagctgctgg tggacgaggc actgaacccc     60
tactatgggt tccaggcctt cagcatcgcg ctgtggctgg ctgaccacta ctactggtac    120
gccctgtgca tcttcctcat ttcctccatc tccatctgcc tgtcgctgta caagaccaga    180
aagcaaagcc agactctaag ggacatggtc aagttgtcca tgcgggtgtg cgtgtgccgg    240
ccarggggag aggaagagtg ggtggactcc agtgagctag tgcccggaga ctgcctggtg    300
ctgccccagg agggtgggct gatgcctgtg atgccgccct ggtggcyggc gagtgcatgg    360
tgaatgagag ctctctgaca ggagagagca ttccagtgct gaagacggca ctgccggagg    420
ggctggggcc ctactgtgca gagacacacc ggcggcacac actcttctgc gggaccctca    480
tcttgcaggc ccgggcctat gtgggaccgc acgtcctggc agtggtgacc cgcacagggt    540
tctgcacggc aaaagggggc ctggtgarct ccatcttgca mccccggccc atcaacttca    600
agttctataa acacagcatg aagtttgtgg ctgccctctc tgtcctggct ctcctcggsa    660
ccatctacag catyttmatc ctctaccgaa amcgggtgcc tctgaaatga gaattgtaat    720
ccgggctctc gacctggtga ccgtggtggt gccacctgcc ctgcctgctg ccatggactg    780
tntgcacgct ctacgcccag agccgactgc ggtagacagg ggcattttct gcatccaccc    840
actgcgcatt nacctggggg gcaagttgna gttggtgtgt ttcgacaagt ggggccgcat    900
gggggttggt g                                                         911

<210> 462
<211> 1063
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1017)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1018)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1019)
<223> n equals a,t,g, or c

<400> 462
cttgatgcca aaaaggcggg gggagctctc caccctgttt gacgtgggcg gaatctttgg     60
tgggatcctg gcaggtgatc tcanaccgac tgggagaaaa gggcctccac ctgcggcctg    120
atgctgctgc tcgcggcccc cacgctctac atcttctcca ccatcagcaa gatggggctt    180
gaggccacca tcgccatgct gctgctcagc ggagccctgg tcagtgggcc ctacacactc    240
atcaccaccg ccgtctccgc cgacctgggg actcataaaa gtctgaaagg caacgcgcac    300
gccctctcca ccgtgacggc catcattgac gggacgggct ctgtaggagc agccctgggc    360
cccctgctgg ctgggctcct ctccccgtcc ggctggagca atgtgtttta catgctgatg    420
tttgcagatg cctgtgcctt actgttcctg atccgcctca tacacaagga gctgagctgc    480
ccagggtcag ctacggggga ccaagttcca tttaaggaac agtgacaccc caccccagtc    540
ccgtggaggg ggtctgggcc cacccttcac aactgccttt caaggacagt tcagacaaag    600
ggccctgcat ggaaagagtg acctcccttt gccttttgca cacgcacctg gaaaagacac    660
agaagccaac ctgagaaccc ctggtgctat tttaaaggag acatattgct gaacagcagt    720
gagaaaagtc tgcaggaact gctgcctgag ccaagccaga gaaccgaaga cccggccggc    780
cctggctcac aggcgtgtgc ccatgcagcc acccaaatgc acgcgtgaca acaaggccgg    840
gagggtgggg ggggtgcaca ggtagccccg accctctcag gcattycagc cacagaacat    900
caaagtgagc gagtactgcg ctggctgtgg cttcagagaa cctgtatgtg ccacgtggaa    960
aaacaggaca ccagagccca ccagacagtg ccggccagca gagaagcaga aagccannnc   1020
cacacaacat caagaaggcc gacaaccagg ttggaagcca agt                     1063

<210> 463
<211> 726
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (613)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (669)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (698)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (714)
<223> n equals a,t,g, or c

<400> 463
gcaaaaagct ggaatgtttg agctcaagga cttggtttca ggagggggta caaatattgc     60
cctgccttca gtgttgatat tgaccaagaa cagctcatcc ctgcctctcs syraaccaac    120
tctattaatc tgctttaagt agtcacaaaa taattcatgt gctatttagg aataaaataa    180
ttccaaatgt tgacacctca ccttttatct trtaagatac actattgaat ggccccagaa    240
cttaggatct gaagaataaa tgattcttgt ccagtcatcg ttgactcggg ccttggtttt    300
tttgtttgtt tgttttttgt tttgcttcct tggactcagg aacttgtggt tcaggttttt    360
gcctgttggt gagtgacctg tggtctagct gacatgcagt ggcccatgtg tacattcatg    420
ccccacagct gcctgggtag tacccagagc cccatccctt cctgtgcaca cgccatctgt    480
gccctccttt ctgcctccaa gggcaggtgg cagagtccac cattcagagc cactggggct    540
ctctgtgtcg gtggtagcct gggttgctgc ttgtggtgcc tccagaagcc attcaggatg    600
ccctccggag cangcccatc aacgcggaga gtgcttagca cagccgtggc tcaagagccg    660
tccctccant cccacgaaat gactcctctt cttttccntg cagaaggtgt gcangttttt    720
agcaag                                                               726

<210> 464
<211> 2062
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1998)
<223> n equals a,t,g, or c

<400> 464
cactagaggc agaggggtga acaagatacc cttctgcctg gggggatgtc cacttcccat     60
gggtttggct atttccagga aagcccctca gtcctccacc ctgttctggc tgtktgtgaa    120
ggatgtgtgt gagcaggccc aatcctttgc agcaagaatg agaggtcaga gtattccatt    180
gcacacgcac cctggggctg acagacttgt gccccctagc cttcatgcat gcccaagcac    240
tggcagcttt gcagcccctg ccccaccagc cccttgacgs tcttyttttg ttctctcctc    300
ggggatgagc tctgctgctg agtagggagc ttttgcttgc tgggaggctc tatggcatgg    360
atttttttgg tgaccataca gytagggctg aggatgggaa cwgggacaga gggcctggct    420
atccctagaa gcacttcatc catctttacc cacccaaacg ggatcccttc acatctcata    480
cccagtaaga tgcaagaaag gaatatctga gagcaagcag ccctgctcca ggggccccag    540
gtatgtgtag aggcccagtg ggggtggcca cttggtgttt ctaccacccc ctgccatcca    600
gtctggcccc agtacctacc tgggaggttg gtgtacttgg cttaagtact tcatgcttta    660
ttcaggctgc ttccccacag caccggcagg aaatgaaggt gcacttatat gcatccctgc    720
aggaataaag agtgggtggc ctgcccagcc cagcaccacr gcctttcccc agccagggag    780
agaccaccta aggwtcaagg cagctcctgt tttcttggtt ctgtgacact cgagtctgag    840
ccagcccytc aggaattgcc tcaaaagaga aaaacaaaaa aaagtcctcc ttcccaaggc    900
ctgctactcc aaggtttggc tccatccctt gcctttgggt cctgcctatt tccccactcc    960
tggtctctta tctttggggc caccagtggg gagtcacccg ggccccaatc cctctaaggc   1020
gctaagttga aggaggcctt cccagagtga ctattggtgc caaagtccca gttcctgttg   1080
gacttggggt aaaaacagga gatggtgagt gggtgtaagg cccaaatgcc cagagaagtt   1140
aactcgaacc catgggacct gtcccagcct gtcagtccct gatgagtgta acttccttcc   1200
cctgggggcc tggcccttct ctccaaccca gtggccatgc tttctcaccc agccttgtgc   1260
ccggcctgca tttctgtata tattgctgtg tattgtgtgt atgtatgtat tcctggacaa   1320
gtgtgttcat ctgcagccct tgcctgagga taaggtttag gattgggtaa agatcagaat   1380
accagggcca gctaaggcaa cgactccctc cccaaaccct tgggacctca gccagtccca   1440
aggctgccct gacaatcagg caggctcccc accgtgaggc caagcctcct ctgccactgc   1500
cagcatggcc caagggaggc ttggccttgg gcttgccagc ctcagctctg ccctgacaag   1560
ggtcttgtat ccagggcaga ggcctgaggt gacccaggct tgctttgtgg ctgatgccag   1620
caggcttggt tctagtgggc accactggtg ggcaacctcc ataactggcc cttaggccct   1680
accttcctac acagctaggc tataatgggc ctgagtgaga gggtagcttc cccagcccca   1740
agcacaggca gaggggtgga gagcaatttt tggttttatt tttgtttctg aagtggtgcc   1800
tgtacctcca gcccccaggg ggccttccct ggccacactt ctctgcccca cccaggcatc   1860
gccatcccag cactttgctc catgtcaccc gtaagatgcc ctttgctgaa tgtacctgag   1920
tgtatgtatt taaaaggact cacatgggca tcagagaatt tatggctctg tatccaataa   1980
aaaagatggt gaaactgnaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2040
aaaaaaaaaa aaaaaactcg ag                                            2062

<210> 465
<211> 1459
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (307)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1393)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1394)
<223> n equals a,t,g, or c

<400> 465
tttttttttt gggattttta atctttaatt ttcaagatgg ttaaaatatt gaaatgttta     60
agtggataac tatattattc ataaaatgac tgagtgaaaa ctaatatact atgagatgaa    120
aagtacttgt cagggatttt caagcttttg ctcaagtaat taccatgaag taacaatttc    180
tagaaatgaa gaacaatctg tgaagataaa ttaccattgg tgtggggaaa aaaagccaaa    240
cagaagtaga aaaaggtgta gctggcatac aaatgttatc tacagtgtat ttatatatat    300
atatttntaa aacttttaac taaaaagtaa actttaatgt cgaaaatgca aacttgggga    360
agacagaaaa gatcacacac aaggctgtca cttcacacgt ggaaggttgc acagcggccg    420
ggcagaggcg cttgtcacac ttcccagatg gtcaggcggc caggcagagg cgctcctcac    480
ttcccagacg gggcagcagc tgggcagagg tgctcctcac ttcccagact tttatatttt    540
ttatacttga ccaggtctct tatgtccttt ttctggaaaa ctacttttaa ctactaaagt    600
gattataaat gaaaaagtgg ccaataaagt gactactatc ctcagggctt taaaccagtt    660
gggataatgt ggtaagagaa aaagttcaag gtggaatgct actcccatac ccattattac    720
tgtgactatg gcttcactaa gtctttcaga aataaggaag gcaaaccatg aaaagaaaag    780
aggagctgca ctgctagcta aattaaggta gtctggtttg gctggactac cttctggtag    840
agcaaaaccc catctgatcc cacccaagaa agataggaaa ctggctccat aagccatctg    900
agtaaaagct aatatgggaa tataagtttt tgtcatcagc atgaccagtg gtggagcaac    960
gaaggggatt agtcctgcca gagttacaca taatgctggc tttgggctgt cagttaggta   1020
agtgatggtg cttgagggtc tggctagaag tgcttgcttc tgctgctttt taaagctgca   1080
gggggatgta tgatagcact gtgtcttgct catatacgct ggaaatgatg aggaaagcca   1140
aggccttgga catggggaaa agttttgctg gagagacatc ttgagagaaa gtatatctgt   1200
tctgctggtt cttagtccca ctgggaaaga gtacttcagt atctttgaag atgcttgaga   1260
aaacttctgg atgaagcgaa gcatactggc ccctattgaa agtcttgttc aggaagatgc   1320
caggtagttc tgattaacat gttacagcta agcagaggca ctgaatcagg ggcatgtttc   1380
agcgttgcac ggnnagaagg aaaacaaccg caacaacagc ccaggtccac tggaaaggca   1440
cttccggcaa gtggattca                                                1459

<210> 466
<211> 608
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<400> 466
ccggacgtat tctgcgctca atggcgatgg gcggttccgc accgagtttt atggcgaaaa     60
tgagtcgtca gcatgtgccg tatgccggga ttctggcgac actagttgtg tatgtcgtcg    120
gcgtattcct caactatctg gtgccgtcgc gcgtatttga gattgtgttg aacttcgcgt    180
cgctgggaat catcgcttca tgggcgttta tcatcgtgtg ccagatgcgc ctgcgtaaag    240
cgattaaaga aggcaaagca gcggatgtca gttttaaact gcctggcgcg cccttcactt    300
cctggctgac attactggtt ttactgagtg tccttgtgct gatggcgttc gattacccga    360
acgggactta tactatcgcg gcgctgccga ttatcggtat tttgctggtt ataggctggt    420
ttggtgtgcg caaacgcgtt gctgaaattc acagcactgc gccagtcgtc gaggaagatg    480
aagaaaaaca ggaaattgtg kttaarcctg aaacggcgag ttaattgcaa aattscccgg    540
ctacgtgccs ggcaaattca gawtactgac gaaagtnccg gatacgccgt gataaaaggc    600
aggcaagt                                                             608

<210> 467
<211> 980
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (530)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (599)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (615)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (750)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (761)
<223> n equals a,t,g, or c

<400> 467
acggatgatg ttgcgcgagg ttgcaaactc ctcacagagt tccgcctcag ccggaagcgg     60
cgagcctggc acgtatttgc cgtgaacgat ctgtttaccc agcgtaatga caatgcgatc    120
ggttttattg agagtcatgg agagtccttg tgctctgtat gttcttctct actttacccc    180
gatcgatgca taacgcggca actttgtagt accagcgtga tgacgttcgc gtttgccgtg    240
cgtgtaatgt agtacaaact tatattgttg tactacaatt tagatcacaa aaagaacaat    300
gcataaaaaa atgacatgcg tcgggcagaa atctgaaaag ggatatcagg cgctaaacag    360
gagggaaaga agagtatgct ttcaacggct tagctactcg tttaaaggat taatcatgaa    420
gttgaatttt aagggatttt ttaaggctgc cggtttattc ccactggcgc tgatgctttc    480
aggctgtatc tcgtatgctc tggtttccca taccgcaaag ggtagttcan gaaagtatca    540
atcgcagtca gacaccatca ctgggctatc gcaagcaaaa gatagtaatg gaacaaaang    600
ctatggtttt tgtangggaa tcgctggatt accttatcac tgatggtgcc satgacatcg    660
ttaagatgct caatgatcca gcacttaacc ggcgcaatat tcaggttgcc gatgacgcaa    720
gatttgtttt aaatgcggga aaaaaaattn accggcacaa natcgcttta ctactactgg    780
aataacgaag aagaaaaggc actggcaacg cattatggtt ttgcctgtgg tgttcaacac    840
tgtaccaggt cactggaaaa cctaaaaggc acaatccatg agaaaaataa aaacatggat    900
tactcaaagg tgatggcgtt ctaccatcca tttaaagtgc gattttatga atactattca    960
cccagaggca ttccggatgg                                                980

<210> 468
<211> 1465
<212> DNA
<213> Homo sapiens

<400> 468
ctcttttaac agtagctgac ctattggatt taaactgaga ctgaaattga catttgtggt     60
taggttatct agctgaggct tttaacaatg gagcagataa tgtctgttcc tgtagtggat    120
ccatttaatt tcctatttga gtactctcac ttaacaagta ttatctattc tgaacctttg    180
tgttgggaat ttaaggacta ttgtcaaagg ctattaatgg taaacaagta tatgcaaaac    240
aattcacata tgggtaaaaa tttcaaattg tgggtttttg tttttgcttt ttagtttcaa    300
agattagtta tgtagcagca atatcataac caaagcaagt aggaagttga ctggtttgga    360
gaatcttcaa gtagttttaa atactgtaat gtatcagatt gttaaccagg attttttttt    420
cctgtattac tgctaaatat attactatat taatgcactt ttgtatatat aactgtcttc    480
tgtacattct gtacttacta cagtgtatat aaagcctgtt ttccctgaag ctgtgaggga    540
ataacaatag ttgtatcata agtcgtttct attttgagtt ccttcttgta cttgaaagta    600
gttcagtagt gaaatctaaa tgagtgtgta tggttgtaat taaaactggc aatgtggcag    660
agctgtcttt tgaaactgaa taccagaatg aaaagtgttg ttttggttaa gaacycttat    720
aatatattat ttcttttgat gtaccctgag ttgttacaca gcccactcac tgctgcttac    780
tactttatac ttctgagtca gctcctttca tgctctatcc cagaatattt accaacagaa    840
ggagaactgc tcccttttct gtttctcaca gtttggttat ggctttataa acttttattt    900
ggtgaaagcc ccagataccc aaatgtcatt ggcaaaactt attttttttt ctggacagat    960
cagatttcta gagagagcag atttctagag agattagcat tcatagtaag tgaaaattgt   1020
ctaatttttt taatccatgc tattactggg cagtaggtct aatttttttt gacaaaaaat   1080
agatctattt tccttatata ttgatttaga atcttaagtt agaattttat agaagaaatg   1140
tctgagcagt tctatgtatg gaggagcaat tcagcttttc agcagcaact ttatcttttg   1200
ccactagagg gagatctgtg gttgctttct cctttggaga atagctgctt tgcttttatt   1260
tttaatttct aaggttggaa tagaacttat tctcaaaatt cctttagtgt tattaaatat   1320
tttcatttat tagtcaaagg taagttaatt aagcttgttt aatgatgcca atcttatgct   1380
tttctgtaat cttcaatttt taataaatgt gagttagata ctaagtgaaa aaaaaaaaaa   1440
aaaaaaaaaa aaaaaaaaaa aaaaa                                         1465

<210> 469
<211> 1143
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1071)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1077)
<223> n equals a,t,g, or c

<400> 469
gccgcatcat gtccaccacc aacgtgcgca agttgatgaa ctgcggaggc ttcggcatgg     60
aagccacgct gctgttggtg gtcggctact cgcactccaa gggcgtggca tnctccttcc    120
tggtcctagc cgtggcttca gcggcttcgc atctctgggt tcaacgtgaa ccacctggac    180
atagccccgc gctacgccag catcctcatg ggcatctcca acggcgtggg cacactgtcg    240
ggcatggtgt gcccatcatc gtgggggcca tgactaagca caagactcgg gaggagtggc    300
agtacgtgtt cctaattgcc tccctggtgc actatggagg tgtcatcttc tacggggtct    360
ttgcttctgg agagaagcag ccgtgggcag agctgaggag atgagcgagg agaagtgtgg    420
cttcgttggc catgaccagc tggctggcag tgacgacagc gaaatggagg atgaggctga    480
gcccccgggg gcacccctgc acccccgccc tcctatgggg ccacacacag cacatttcag    540
ccccccaggc ccccaccccc tgtccgggac tactgaccat gtgcctccca ctgaatggca    600
gtttccagga cctccattcc actcatctct ggcctgagtg acagtgtcaa ggaaccctgc    660
tcctctctgt cctgcctcag gcctaagaag cactctccct tgttcccagt gctgtcaaat    720
cctctttcct tcccaattgc ctctcagggg tagtgaagct gcagactgac agtttcaagg    780
atacccaaat tcccctaaag gttccctctc cacccgttct gcctcagtgg tttcaaatct    840
ctcctttcag ggctttattt gaatggacag ttcgacctct tactctctct tgtggttttg    900
aggcacccac accccccgct ttcctttatc tccagggact ctcaggctaa cctttgagat    960
cactcagctc ccatctcctt tcagaaaaat tcaaggtcct cctctagaag tttcaaatct   1020
ctcccaactc tgttctgcat cttccagatt ggtttaacca attayttsgt nccccgncat   1080
ttcagggatt grattctcac agcgttttgt ggattgggaa aatggggggt ttcaagttcc   1140
ccg                                                                 1143

<210> 470
<211> 1183
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (212)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1134)
<223> n equals a,t,g, or c

<400> 470
ggcacgagtg ctgctgctgc ggcggcggca gcggcgtctg tgcttgtgga ggtgtcggcc     60
tctgggcgga tgttgacatt gtgttgttgt tattgctgat ggtaatggcg gcggcggtgg    120
cggcgacggt ccagacccca tcccctctgt agccggagcc gagacagccg acagcgaact    180
ccgcggcctc ggagccggcg gcagcggcga cntcccctca gcctccgccg cctcgcccgc    240
cggtaccccg gcgccaaccc cgggagtcag gccctttgca ggggagctcg gaggctcagg    300
atggcggatt tcgacgaaat ctatgaggaa gaggaggacg aggagcgggc cctggaggag    360
cagytgctca agtaytcgcc ggacccggtg gtcgtccgcg gctccggtca mgtcaccgta    420
tttggactga gcaacaaatt tgaatctgaa ttcccttctt cattaactgg aaaagtagct    480
cctgaagaat ttaaagccag catcaacaga gttaacagtt gtcttaagaa gaaccttcct    540
gttaatgtac gttggctact ttgtggctgc ctttgttgct gctgcacatt aggttgcagt    600
atgtggccag ttatttgcct cagtaaaaga acacgaagat cgattgagaa gttattagaa    660
tgggaaaaca ataggttata ccacaagctg tgcttgcatt ggagactgag caaaaggaaa    720
tgtgaaacga ataacatgat ggaatatgtc atcctcatag aatttttacc aaagacaccg    780
atttttcgac cagattagca tttactttat ttatagagac tttccaagta tgttgtcttt    840
ccaatggtgc cttgcttggt gctctcctgg tggtgacata acattggttc tacagaatcg    900
tgtggtgttt tttttgtttt tgtttttttt tttttttaaa taaccgcatg ttctaagtgt    960
gcatttttgt caatctttgc aacagttatt tcatacagat gtttaatact taagttattg   1020
tgctcttttc tgttatgtat tctgattttc aaggattact tttttgtatt atcaaaaaaa   1080
tacmtttgaa cttagcataa aaagtggcca gcctttttta ttttgcacca aggnacacac   1140
aggcctttat ttataaattc cttaacagag aaaaacacct ttg                     1183

<210> 471
<211> 458
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (416)
<223> n equals a,t,g, or c

<400> 471
gactaatgca gatttttttt ttttaagttt tatagagatt catgggattt tattcttttt     60
cccaaaggca gtggtggagc tgacagagta gcatggagcc tcgtcctgat gtattgtgcg    120
gaagtggcag cagttcacat tcattcagtt tgtcagcata ggatcagttc cttcttgact    180
caactctctg tgatcaaaat aagctattgg atgttccctt tgggtactgg aagcagcttg    240
gccccttggc aagagaacag gattgcaaat cacaagagca gagccctgac tccagctctg    300
atgctactgt gctttgtgac cttgtgcaga cagctttata tccccatctc aggtcattct    360
cccccataca ragggggaga rggtcatctt gccctggyca tgtctgcatg gctgangtga    420
ataactaayt gtgtaacttc ctggawgagt ggcacaga                            458

<210> 472
<211> 433
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<400> 472
ggggnggcca tggtgtcagg cccgggtggg ggcggccgtg gtgtcaggcc cgggtggggg     60
cggccttggt gtcaggcccg ggtgggggcg gccgtgttgc caggcccggg tgggggcggc    120
cttggtgtca ggcccgggtg ggggcggcct tggtgtcagg cacgggtggg ggcgagggca    180
agagggcaac ggtgggaatc gccatgtggg ctggaccagc taaaggctcg tatttgcata    240
ttaaaggttg ccaagccggg tctaagagcc agggctttca cgctagacaa gaaacatttt    300
ttggagctgc aaaaaatgct tccaaggacc ctttttcctc tctctctctc tctttatttt    360
ttcttttttg gatatggagt ttcactcttg ttgcccagcc yggaagttgc agtgagccga    420
gatcgagcca ttg                                                       433

<210> 473
<211> 950
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (926)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (935)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (949)
<223> n equals a,t,g, or c

<400> 473
cgcgggagaa ggggagaccg cggcggcccc cagtgagagc ggctttccag gacggtgcga     60
tgtgctgcgc acgaagaggc aggaggccgg cttcctgggg tagcggtaca ggcgggcgct    120
tactctgtgc gcttgcttcc ccaaccctgc accggccatg cgcccggcct tggcggtggg    180
cctggtgttc gcaggctgct gcagtaacgt gatcttccta gagctcctgg cccggaagca    240
tccaggatgt gggaacattg tgacatttgc acarttttta tttattgctg tggaaggctt    300
tctctttgaa gcggatttgg gaaggaagcg gccggctatc ccaataaggt actatgctgt    360
gatggtgacc atgtwcttca cggtcagcgt ggtgaacaac tatgccttga atctcaacat    420
cgccatgccc ctgcatatga tatttagatc tggttctctc attgccaaca tgatcctagg    480
aattatcatt ttgaagaaaa gatacagcat tttcaaatat acctccattg ccytggtgtc    540
tgtggggata tttatctgca ctttcatgtc agcaaagcag gtgactttcc cagtccagct    600
cggagtgaga atgatggatt ccaggcattt ttaaggtggc tgctagggat tggggcactg    660
acgtttgcac ttctgatgtc agcgcggatg ggtattttcc aggagacctt atacaaacaa    720
tttgggaaac attccaagga ggctttgttt tataatcatg cccttccgct tcctggcttc    780
attttcctgg cttccgacat ttatgaccat gcagttctgt tcaataagtc agaactgtat    840
caagttccgg tcattggtgt gacagtgccc atcatgtggt tctacctcct catgaatgtc    900
atcactcagg accagtgcat ccggtngtca acganctcac cacggaatnc               950

<210> 474
<211> 2678
<212> DNA
<213> Homo sapiens

<400> 474
gcagagattg gccattccgc tactgcgcaa agatggtgga ggaggagaac atccgcgtgg     60
ttcgttgtgg cggcagcgag ttgaacttta ggagagctgt gttctctgca gattctaagt    120
atatcttctg tgtctctgga gactttgtta aagtttacag cacagttaca gaagagtgtg    180
tacacatact gcatggacac agaaatctgg tgactggaat ccagcttaac cccaacaacc    240
atctacagct gtattcttgt tcccttgatg gcacaattaa actgtgggac tatatagatg    300
gcatcttaat aaagactttc atagttggat gtaaacttca tgccctcttt actcttgccc    360
aagctgagga ttctgtcttt gttatagtga ataaagaaaa accagatata tttcagctgg    420
tttcagtgaa actgccaaaa tcctcaagcc aggaagtaga agccaaggag ctgtcctttg    480
ttttggatta cataaaccag tcacccaagt gcattgcctt tggaaacgag ggagtatatg    540
ttgctgcagt acgggaattt tacttgtctg tttatttttt caaaaagaaa acaacatcaa    600
ggtttacttt atcatcatca agaaataaga agcatgctaa aaacaatttt acgtgtgtag    660
catgtcaccc aacggaagac tgcatcgcat ctggtcacat ggatggcaaa attcgtcttt    720
ggaggaattt ttatgatgat aagaaatata cgtacacatg tttacattgg caccatgata    780
tggttatgga tttggctttt tcagtgacag gcaccagtct gctgagtggc ggtcgtgaat    840
ctgtacttgt agagtggcgc gatgcaacag agaagaataa ggagtttctc ccgcgtttag    900
gagctactat tgaacatatc tcagtctcgc ctgcaggaga tttattctgc acttctcact    960
ctgataataa gataataatt attcaccgaa accttgaagc atccgcagta attcaaggcc   1020
tagtgaaaga taggagtatc ttcactggtt tgatgattga tccaagaact aaagctttgg   1080
ttttgaatgg aaaacctggc cacctgcagt tttattctct ccagagtgat aaacagttat   1140
acaatttaga tattatacag caagaatata ttaatgatta tggtctgatc caaattgaac   1200
taacaaaggc tgcatttggc tgctttggta actggcttgc aacagtggaa cagcggcaag   1260
aaaaggaaac tgagcttgaa ttgcaaatga aactgtggat gtataataag aaaacacaag   1320
ggtttattct taacactaaa attaacatgc cacacgaaga ctgcattaca gctctctgtt   1380
tctgtaatgc agaaaaatct gaacagccca ccttggttac agctagcaaa gatggttact   1440
tcaaagtatg gatattaaca gatgactctg acatatacaa aaaagctgtt ggctggacct   1500
gtgactttgt tggtagttat cacaagtatc aagcaactaa ctgttgtttc tccgaagatg   1560
gttctttact agcagttagt tttgaggaaa tagtcacaat atgggattct gtaacatggg   1620
aacttaaatg tacattttgc caacgagctg ggaaaataag gcacctttgc tttgggagat   1680
tgacgtgttc aaagtatcta cttggtgcta ctgaaaatgg cattctttgc tgttggaatc   1740
tgctgagctg tgcattggag tggaatgcaa aattaaatgt tagagttatg gaacccgatc   1800
ctaattcaga gaatattgct gcaatctctc agtcttcagt gggttcagac ttgtttgtat   1860
ttaaacctag tgagccaagg ccattgtata ttcaaaaggg tatctccaga gagaaagtcc   1920
agtggggagt gtttgttcca cgagatgtcc ctgaatcctt cacctcagaa gcttaccagt   1980
ggctaaatag atcccagttt tacttcctaa caaaatcaca gagtttattg acattcagta   2040
caaagtctcc agaagaaaaa ctcacaccaa caagcaaaca gctgctagca gaagaaagtc   2100
ttcccacaac cccattttat ttcatattgg gaaaacacag gcaacagcag gatgaaaaac   2160
taaacgaaac tttagagaat gagctggtac aactaccctt aacagaaaac atacccgcaa   2220
ttagtgagct tcttcacact ccagcccatg tcctgccatc tgctgctttc ctgtgctcca   2280
tgtttgtaaa ttcattgctg ctgtctaaag agactaagag tgctaaggaa attcctgaag   2340
atgtagatat ggaagaagaa aaagaaagtg aagattcaga tgaagaaaat gattttaccg   2400
aaaaagtcca ggatacaagt aacacaggtt taggagaaga cattatacat cagttgtcaa   2460
aatctgaaga aaaagaactg agaaaattta ggaaaataga ctacagctgg atagctgccc   2520
tttaagcctt ggagatgggg aggatccttg gactttgtgt ttttgattgt atgttgatat   2580
tctaaaaaca tctattttaa tgttatttct gttctaaaaa taagataata aatattaaca   2640
aactttgctt ttttaaaaaa ctgaaaaaaa aaaaaaaa                           2678

<210> 475
<211> 1047
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1043)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1044)
<223> n equals a,t,g, or c

<400> 475
gccgcgcccg gccagcctga ggtggggtcg gtgcccccgg sggcacggcg ctggggaggc     60
gatggcgccg gccgcgtcca ggctgcgggc cgaagccggg ctcggggcgc tgccgcggcg    120
ggcgctcgcc cagtacttgc tcttcctgcg gctctacccg gtgctcacca aggcggccac    180
cagtggcatt ttgtcagcac ttgggaacww cctggcccag atgattgaga agaagcggaa    240
aaaagaaaac tctagaagtc tggatgtcgg tgggcctctg agatatgccg tttacgggtt    300
cttcttcaca gggccgctga gtcacttctt ctacttcttc atggaacatt ggatccctcc    360
tgaggtcccc ctggcagggc tcaggaggct tctcctggac cgcctcgtct ttgcaccggc    420
cttcctcatg ttgttcttcc tcatcatgaa ctttctggag gggaaagacg cctcagcctt    480
cgccgccaag atgagggggg gcttctggcc ggcgctgagg atgaactggc gggtgtggac    540
gccactacag ttcatcaaca tcaactacgt ccctctgaag ttccgggtgc tcttcgccaa    600
cctggcagct ctgttctggt atgcctacct ggcctccttg gggaagtgac gaccgctggg    660
agaacatcag gtgcactgtg gacgtgggtc tgggggtctc acccgcccag cgagagcaga    720
accaatccag tcaggatgtc actgactcta aatcaggtga ttcaagatgc ccaaaaatga    780
tggatagaga aacagaaatc tctgaatgtc agaaccctgt cttttaaaaa ggcagtcrct    840
gccttcaggt ggtgctgccc cagaaactta aaatttagtc gaggcagttt caattgttac    900
tgtggaccga attaggatca caataaacga taatgcaggt tcttcaaaaa aaaaaaaaaa    960
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ctcgaggggg ggcccgtacc   1020
caatcgccct gatgatgatc tgnncac                                       1047

<210> 476
<211> 1568
<212> DNA
<213> Homo sapiens

<400> 476
gctcggcggc ccttgggctc tgcgggctgg ggactcgggg tgcccgckac acgcgcggag     60
gcgcgggctg ggttggccac gggcagggag cgcagccgcg ctccttcctc tctgcccgcg    120
tcgcctccgc gcgcactggt tctgcgcggc ggggcttggc ctgcgcgact gtctactccg    180
tcccggcggc ctcggagccc ggccgagcgg cgagcttgtc agaggacggt ggtggaaacg    240
ctcccggcct ccccaggggc rcgggctgga ggctggcgcc aggcgcggag gactcccggt    300
atcttttgac aggctggcgc ctcggctctg gggacccgca ggaatyaagt ttagacttga    360
aattcaagtt tttcctgaaa ctgatcagaa gttagtgaca ccttgattgg atccgttttt    420
ctgtcaggag ctcattttgc agctctcaag cttttatagc atgctgtaaa caattgtcaa    480
agttgtttat caagaaacag atagagttgc aacttgkttc tagtaataga aacttttaca    540
ctgcattcaa tgcctaacgt tgcagaaaca gaaaggtcaa atgattctgg aaatggtgag    600
cacaaatctg agagaaagtc acctgaagag aatctacaag gtgctgtaaa atctttctgc    660
acaagtgcct caggagcacc cttgggtccc aaaggagatg gtcattatcc atggagttgt    720
ccagtgactc atacacggga aaaaatttat gccatctgtt cggactatgc ctttctcaac    780
caggcgacct caatctataa aactccaaat ccatcccgct ctccttgcct ccctgatagt    840
acctctttat ctgctggaaa taattcatca agatacattg gtatcccgac tagtacatcg    900
gaaattatct acaatgaaga aaatagcttg gaaaacttat ccaacagcct gggcaagcta    960
cctctcgcat gggraattga taaatctgaa tttgatgggg tgaccacaaa ttcgaaacac   1020
aaatcaggca atgcaaagaa acaagtttcc aagagaaaaa cttcagataa aaagggaaga   1080
tatcagaagg aatgtcctca gcattctcct cttgaagata ttaaacagcg gaaagtatta   1140
gacctcagac gatggtactg cataagccga ccacagtata agacttcttg tggcatctct   1200
tcattaattt cttgttggaa tttcttatac agcacaatgg ggagctggga aaccttccac   1260
ctattaccca agaagaagct ttacatattc tgggctttca acctccattt gaagatatta   1320
ggtttggtcc tttcacgggg aatacaacac ttatgaggtg gtttagacaa attaatgacc   1380
acttccatgt aaaaggatgc tcttatgttc tatataagcc tcatgggaag aataaaacag   1440
caggagaaac tgcttcaggg gccctgtcaa agttaacccg tggattgaaa gatgaatcgc   1500
tggcttatat ctatcattgc caaaatcayt atttttgtcc aattggcttc gaagcaaccc   1560
ctgttaaa                                                            1568

<210> 477
<211> 2552
<212> DNA
<213> Homo sapiens

<400> 477
gcgaagagct actctgaaaa gatcatttac tcctgtattt ttgggaagcg ccttgaagaa     60
caaaggagtt cagcctcttt tagatgctgt tttagaatac ctcccaaatc catctgaagt    120
ccagaactat gctattctca ataaagagga tgactcaaaa gagaaaacca aaatcctaat    180
gaactccagt agagacaatt cccacccatt tgtaggcctg gcttttaaac tggaggtagg    240
tcgatttgga caattaactt atgttcgcag ttatcaggga gagctaaaga agggtgacac    300
catctataac acaaggacaa gaaagaaagt acggttgcaa cggctggctc gcatgcatgc    360
cgacatgatg gaggatgttg aggaagtata tgccggagac atctgtgcat tgtttggcat    420
tgactgtgct agtggagaca cattcacaga caaagccaac agcggccttt ctatggagtc    480
aattcatgtt cctgatcctg tcatttcaat agcaatgaag ccttctaaca agaacgatct    540
ggaaaaattt tcaaaaggta ttggcaggtt tacaagagaa gatcccacat ttaaagtata    600
ctttgacact gagaacaaag agacagttat atctggaatg ggagaattac acctggaaat    660
ctatgctcag aggctggaaa gagagtatgg ctgtccttgt atcacaggaa agccaaaagt    720
tgcctttcga gagaccatta ctgcccctgt cccgtttgac tttacacata aaaaacaatc    780
aggtggtgca ggccagtatg gaaaagtaat aggtgtcctg gagcctctgg acccagagga    840
ctacactaaa ttggaatttt cagatgaaac attcggatca aatattccaa agcagtttgt    900
gcctgctgta gaaaaggggt ttttagatgc ctgcgagaag ggccctcttt ctggtcacaa    960
gctctctggg ctccggtttg tcctgcaaga tggagcacac cacatggttg attctaatga   1020
aatctctttc atccgagcag gagaaggtgc tcttaaacaa gccttggcaa atgcaacatt   1080
atgtattctt gaacctatta tggctgtgga agttgtagct ccaaatgaat ttcagggaca   1140
agtaattgca ggaattaacc gacgccatgg ggtaatcact gggcaagatg gagttgagga   1200
ctattttaca ctgtatgcag atgtccctct aaatgatatg tttggttatt ccactgaact   1260
taggtcatgc acagagggaa agggagaata cacaatggag tatagcaggt atcagccatg   1320
tttaccatcc acacaagaag acgtcattaa taagtatttg gaagctacag gtcaacttcc   1380
tgttaaaaaa ggaaaagcca agaactaact ttgcttactg tgagttgact gactctaatt   1440
gaatctgcgt ggttttgata ctttgatgga ttccagtgga ataaattcag gctgctgaaa   1500
caagaaattc tgagcccagg aagcgggctc ttctttcttc aaaagaagcc cttcttgttc   1560
atattcagga gcttctgtta tattcaaagg taattctatg tctatctcaa ctctattgat   1620
tggttttata gttyattgaa aatcctcaaa taaaatataa ttattactga aatatgttta   1680
atatttaagg ggaaaagaga ctaatttcag ttatactttt aagcttagaa tgtatgttca   1740
tttccaaatt ttgtatcata agagttttca acatagagaa aagctgaaaa aatgcaaaga   1800
ataaccacat actttccatc taccttcctt tgttaacggg ttgtttatca tataataatt   1860
tgttttgtca tatttgcttt cactgtctat tatctgttta agtctcataa ctctattttt   1920
agtttgctga agacttgaaa gtgaatcgca tatatcatga cacttcttgg agtgtcatta   1980
atgggcaggc ttttctgttg aagagtggat tccgtatgtt cttcatagag agtgtttttc   2040
agattcttca ttgggatatt aaaatattag ccaaatttct ctctgtttta tatatgtcag   2100
tttatttcag tttgtggttt ctgcaaattt gtaactgcct ctgttttagg agtataagta   2160
ttacttcctt gtggtctatt gtgaagtaaa aagtagaccc ttgcatatac tattcttgtt   2220
tgtgttcatc ttaatgtttt tgtacagcta aatcaaatgt aatttataga gttagtttca   2280
tcaacctaat gaatgctagt taaatttgaa ttccttggaa tttatcgtat attgtattca   2340
ctgagattat gaagggacaa atgttaatct tttgtttcca gaaaaagttg ggctttccca   2400
agcagttcta ttacccggtt cagaattgct tcatccaaaa atcatctgat ggtatagatg   2460
gatcctagtc cttttcatta cctgatggta gaaataaaat aattgatttt aaaaaaaaaa   2520
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 2552

<210> 478
<211> 1670
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1639)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1653)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1663)
<223> n equals a,t,g, or c

<400> 478
gctttctcat ccggccggct tgctttcccc tgcggtcgtc cagactattg ggcgctagcg     60
agacgaacta ttggtacggg gctagagagg aaggctttgg gattgccggg gagcagcgag    120
cgaccgactt ccgtttccag ttaccaaggc acgaggatcc ggtgttccaa cccaggggga    180
aaaatgcggc ctttgactga agaggagacc cgtgtcatgt ttgagaagat agcgaaatac    240
attggggaga atcttcaact gctggtggac cggcccgatg gcacctactg tttccgtctg    300
cacaacgacc gggtgtacta tgtgagtgag aagattatga agctggccgc caatatttcc    360
ggggacaagc tggtgtcgct ggggacctgc tttggaaaat tcactaaaac ccacaagttt    420
cggttgcacg tcacagctct ggattacctt gcaccttatg ccaagtataa agtttggata    480
aagcctggtg cagagcagtc cttcctgtat gggaaccatg tgttgaaatc tggtctgggt    540
cgaatcactg aaaatacttc tcagtaccag ggcgtggtgg tgtactccat ggcagacatc    600
cctttgggtt ttggggtggc agccaaatct acacaagact gcagaaaagt agaccccatg    660
gcgattgtgg tatttcatca agcagacatt ggggaatatg tgcggcatga agagacgttg    720
acttaaaacg aagccattcc aaggacagac ggctgtatgg aaaggccgag ctttgtttcc    780
tgtgtttgtg tggactccac catcatgttg aattttgtca acactctggc ctcttcaggg    840
acttcttatt tactgtactc tctatcactg acaaatgcag gctggattct tattatatac    900
agagatggct caaaaatggg gtttcagatc tttgtgacga aatagaatac tgtttcatat    960
ttgaatcaga gggcttcttg ttctgagaaa taggttcaaa atcattggaa ccaggaacaa   1020
gaatagctta ttgttatctg tgataacact gttttctaaa cacaaggatt ttctttttta   1080
ttaatatgca acatagacat tgccataaca gaataataaa ccacatgtgg ggttttaaaa   1140
atgaaatttg gctaatagga gcaattcagc tatttttcta tacagtaatt ggtgtgtggt   1200
atagaagaaa aacgggttca aaccccactt ctgccaccta ccagctatat ggccttgaat   1260
gagtcattca gctttaataa ggttcatttt cttctgttta aaaagacaca aaacttgaaa   1320
atcagctttg gccatctacc tgagaattag aaagtctgat ttttggaatt agaaatcatg   1380
attgtaggct gggcacagtg gctcgcgcct gtaatcccag cactttggga ggccaaggcg   1440
gacggatcac ttgaggttag gagtttgaga ccagcctggc caacatggtg aaaccccatc   1500
tctactaaaa aaaaaaaaaa aattaggtgt ggtgacacat ggctgtggtc ctagttactt   1560
gggaggctga ggcaggagaa tggcttgaac tggggaagca gagcttgcag tgagccaaga   1620
tggtgccatt gcacttcanc ctgggcgtga canaatgaga ctncatctga              1670

<210> 479
<211> 741
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (628)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (687)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (688)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (706)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (725)
<223> n equals a,t,g, or c

<400> 479
agcggggcca gagcagcaat ggcggcgggc ggcggcggta gctgcgaccc cctggcccct     60
gctggggtcc cttgcgcctt ctccccgcac agccaggcct acttcgcttt ggcctctacc    120
gacggtcact tacgagtatg ggagacggcc aacaaccggc tgcaccagga gtacgtgcct    180
tccgcgcacc tcagtggtac ctgcacctgt ctggcctggg cgccagcgcg gctgcaggcc    240
aaggaaagtc cccagaggaa aaaaaggaaa tcagaagctg taggaatgag taaccagact    300
gacttattgg ctcttggcac agcagttggt agcattttat tatacagcac agtaaaagga    360
gagttacaca gtaaattaat aagtggtgga catgacaaca gagtcaactg catacagtgg    420
catcaagaca gtggctgttt atatakttgt tcagatgata aacatattgt ggaatggaac    480
gtacagacat gcaaagtaaa gtgcaaatgg aaaggsgaca atagcaagtg tmagttccta    540
tgtwtmaccc agatggaaag atkttgcttt cagctggtcg aacaatcaac tatgggtttg    600
gagaccaaaa agttacaggc atttacanga cattgcaacg ccagttcgta ctgaggttac    660
ttacatcaga cttctaatga gagccanncc tttgatggat tcaggnttat ttttatctga    720
gcagncatga ccgttctaat g                                              741

<210> 480
<211> 2879
<212> DNA
<213> Homo sapiens

<400> 480
gagactgggt tggcagcsag gctggagaag ctgtgaccag cctggaacgc caggcccagg     60
caggtggact tgaaacttac tcacaagaag caaagagccc tgttggaaag gtttgacatc    120
tacaggaagg tgcccaagga ccttacgcag ccaacgtaca ccggggccat tatctccatc    180
tgctgctgcc tcttcatcct cttcctcttc ctctcggagc tcaccggatt tataacgaca    240
gaagttgtga acgagctcta tgtcgatgac ccagacaagg acagcggtgg caagatcgac    300
gtcagtctga acatcagttt acccaatctg cactgcgagt tggttgggct tgacattcag    360
gatgagatgg gcaggcacga agtgggccac atcgacaact ccatgaagat cccgctgaac    420
aatggggcag gctgccgctt cgaggggcag ttcagcatca acaaggtccc cggcaacttc    480
cacgtgtcca cacacagtgc cacagcccag ccacagaacc cagacatgac gcatgtcatc    540
cacaagctct cctttgggga cacgctacag gtccagaaca tccacggagc tttcaatgct    600
ctcgggggag cagacagact cacctccaac cccctggcct cccacgacta catcctgaag    660
attgtgccca cggtttatga ggacaagagt ggcaagcagc ggtactccta ccagtacacg    720
gtggccaaca aggaatacgt cgcctacagc cacacgggcc gcatcatccc tgcaatctgg    780
ttccgctacg acctcagccc catcacggtc aagtacacag agagacggca gccgctgtac    840
agattcatca ccacgatctg tgccatcatt ggcgggacct tcaccgtcgc cggcatcctg    900
gactcatgca tcttcacagc ctctgaggcc tggaagaaga tccagctggg caagatgcat    960
tgacgccaca cccagcctaa tggccgagga ccctgggcat cgccagcctt gcctccagtg   1020
ccctgtctcc tttggccctc aatctggtcc caaatctggc tgtgtcccaa agggtgtgtg   1080
ggaagtgggg ggaaagtaga ggatggctcg atgttttgca gctacctctt ttccccgtgt   1140
ttctttttag acaaattaca ctgcctgaag ttgcagttcc cctttccctg gggagcccca   1200
agaacagagt caggcaaggg gtggggagtc cagggatctt ggggacccct cctaggagag   1260
ctgcagtctc ttccctcagg ggaacatccc agaatgcata tcgatcagct ctcagccagg   1320
cttcgacaat ctcgcagccc ccactaggtg gacacattaa tgatttggtt tctcccctgg   1380
gcagccaacc tgccccagag gcaccagacc tgggctttca gctttgggac caggctgccc   1440
aaaggtactc ctttatacac ccggcacctt ccacgaaaga tggtacttcc caagcaagcc   1500
cctatgattt gtcactatag atggaaccct gacttctgcc ccatcccttc ctgcccaacc   1560
tagaacccag gcctcaagtc tttaccccac ccctttcttg ttcttccaag aagcagatgc   1620
ccagttgctc agcagcagcg gtagagactt gaatctgccc accagtcaca aggcgggtca   1680
cagattcctc ttcctctctt ctcctcgttc ctctgaaccc tccaccaatg tgcctcagcc   1740
tgtgtgctgt gtggcaacag cattctggtt cccactgcca agatctccca ccactctgct   1800
gggatctgca gtggcaggga gtgggggttg tgtaaagggg aagtcatctt ttgagatcca   1860
gatagacatg gtttgtgcac ttacgtccag atgggaagca tccttcctgc aaccctaaaa   1920
taatcatgca gcctctcaga cggacgccat cggtcccaag gccttaggtg gaggaagcaa   1980
agcaggccag gcctgtcctg tccgtggacc tctaccttct ggactcccta cgggtgcaga   2040
gcacttgggt ttctctacag ccatcgtggc ccacttgaca ctgtgctcct ccatcagctg   2100
gtcacatgcc aacacgttcc cagcccctga ggcagctcca gggtgcccca cctgctcctg   2160
aggtgggtcc ctaccctgct gctcctcttc atcctttccc ttttgtcctg aaagggagga   2220
gcaatggtcc aggcattaat tccacccagg gaattttagc tatgccctca tgtcccaggg   2280
agagagccac acgcctgttt tccatttata gcaagattgt ttgcatactt ttgtaatgaa   2340
ggggagtgtc cagtggaagg atttttaaaa ttatcttatg gatagctcaa gtctctgcca   2400
tttgtaattt ttggctctaa gctccgattg gagacgcttc tccttgtgca tgtgagttga   2460
ctgatgttgt gagtgtaaat gcatttggtt atttctggta tcggtggcca cttggatgga   2520
tttttttaca ttctgttccc cagttacagg aaggagtccc tttggtgtgt gaatatgtgt   2580
gcctgtagag ggtggggcag ggtggggtgg ggatggaaat gtgtggcatg cacatgagtt   2640
gaaattcttt tatgcatttt tttgaagaaa aaaaaaaaaa aacaactctg aggacatagg   2700
ggatgtcagt ttcctatgga agagacacct ctgacccgtt attcttataa tcaaaatctg   2760
aagggaaaaa aatgttttag ttctttcccc actcgttggg ttcaactaga ttaaaaggct   2820
gattttcaga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa    2879

<210> 481
<211> 3301
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (142)
<223> n equals a,t,g, or c

<400> 481
aattcggcac gagaggccgc ctctracgcc accggctggg ctccgccatg agttcggcgc     60
cggcctcagg ctccgtgcgc gcgcgctatc ttgtgtactt ccagtacgtg ggcaccgact    120
ttaacggggt cgcggccgtc angggcactc agcgcgccgt cggggtccag aactacctgg    180
aggaggccgc cgagcggctg aattccgtgg agccggtcag gttcaccatc tccagccgca    240
cggacgccgg ggtccacgcc ctgagcaacg cggcgcacct ggacgtccag cgccgctcag    300
gccggccgcc cttcccgccc gaggtcctgg ccgaggccct caacacacac ctgcggcacc    360
cggccatcag ggtcctgcgg gccttccgag tgcccagcga cttccacgct cgtcacgcag    420
ccacgtcccg gacctacctg taccgctggc actggytgtc accggcgtga tgarctgccg    480
gtgtttgaac gcaacctatg ctggactctc ccggcagact gcctggatat ggtcgccatg    540
caggaagccg cccagcacct cctcggcaca cacgacttca gcgccttcca gtccgctggc    600
agcccggtgc cgagccccgt gcgaacgctg cgccgggtct ccgtttcccc aggccaagcc    660
agccccttgg tcacccccga ggagagcagg aagctgcggt tctggaacct ggagtttgag    720
agccagtctt tcctgtatag acaggtacgg aggatgacgg ctgtgctggt ggccgtgggg    780
ctgggggctt tggcacctgc caggtgaaga cgattctgga gagccaagat cccctgggca    840
agcaccagac acgtgtagcc ccagcccacg gcttattcct caagtcagtg ctgtacggga    900
acctcggtgc tgcctcctgc accctgcagg gkccacagtt cgggagccac ggatgaccct    960
ggacactcaa gccaaagtta ggccacacca ggcccaaccc tgtgctggtc aagccagggc   1020
agtcacagct gcttggggcc cacagcactg ctgcctggtc tccacagtag cctccctgcc   1080
cgggtcccag caccctggat gcccgtctct gtcccaggcg ggatggggca cagtgcagga   1140
cacagccatg tacaccaaga agagagtacc aagtagtctt ttgttcagct tttactggaa   1200
actgctgtct aggaccacct gccctaacca ggaataaagg caagacagcc tggagaccag   1260
tttgtttctt cagctgcaaa cagctgcctg ggcaggcagg tgacacaagg cctctgtccc   1320
cagggatggg acctgcaggg tctgttcacc cagggcaccc acagtcctga agtgcaggcc   1380
cagggtctgt ccagctggga gagggcagag gtggcggctg ggtgagttgc cggcctcagc   1440
tgggggcctg ggggaggccc ttcttcagca gagatgtgag gaagctcccc agctcctcgt   1500
cctggtaggt ccaggagacc agcagcacct tggtgcctgg gtcctcagaa ggggcggcgg   1560
cctggaggag gacggactcc acagtcacag agccgtcygg gaggtgctgc acacagtggt   1620
ccttcaggac gctcttgagg tggctgtaga cgcgcaatgc cgtctcctgc tccttgcgtg   1680
tgtcatgcag gtgcacgcgg caggtgaagc gcagctggtg ctcagccaga cccagctctt   1740
tgagggcttg ctctgaggac accagccgga agttgctgtc cttcatgatc agggtgccgt   1800
gcaggagccg aggcttcttg gcctcaggga gcagcccctg cgccatctcc cgcttcagca   1860
gccccagcga gatgcctacg gggatgctgg ggcttgtggg cagcgtcacc gtctcgccat   1920
tggccggcat gtagcagttg acccggagct cctgctcgat cttctgcttc aggaactcca   1980
tcttcttggc ctcgccatgc accagcagca cgctctccgg ctctgcctgg cccaccagct   2040
gcatgatgcc cttggcgtcc gcgtgtgcgc tgaatgacat gtactccacc tgcatcttga   2100
cctccagcac ctgccgcccc tccatctcga gcttccgctg cccgctgagg atcttgtggc   2160
cgacggtgcc ctgcacgcag tagccgggca tgatgaccat gttcttttcg tttccggccc   2220
atttccggaa gatctgcagg gactgcccag cgtgcagcat tcctggcgtg gcaaacacaa   2280
ccatcggtcc tgggttgtca gcaaaagccc ggtcgaaggc cttgatgtgc ttgaactcaa   2340
acatgttcct ctgcacaaaa gtcttgcgga tcttctggtt ggtccagggg atgaacagct   2400
tgtagtagtg gttggccttc tcggtcagcc ccgtggagaa gtagatgggc accttcaggt   2460
tcatgcgctc ccagaaggtc tccaggagga tgcagagctc ctgggcgcgg cccagcgcga   2520
acacaggtat cagcaccttc ccaccacgct ccacggtctc gtggactttc ttcaggaagt   2580
ctcgctcccg gcagcgcttg gagtcacgga tggtcgtggc gtacgtggac tctgtgatga   2640
gcaggttggg gcggcacttg tcaatccagg cagctcctaa gtgtcggtct ggggtcatgt   2700
tataatcacc cgtgtagacc acagactctg agcccacttt aatctggaac atggctgccc   2760
ccagcacgtg gcctgcatag taggccttga tctccagctc atcatctacc tggaccgtct   2820
ggtggaggtg gacagccacc accttcttca tgcagtcttt gatcatctgg gaggtgaaga   2880
agttggcctc gcccttcttg tctacggcga tcttgcggta gtcctccagc aagatggggc   2940
agatggcctg ggtggggtga gtcatgtaga tggggccgtc gtagcccacc atctcgctga   3000
agtaggggag tgccccgcag tggtccaggt ggaagtggct aatgatcaca cagtccagga   3060
agtctgttag gcggccgttc tgggtgatgt aggagaagtc agggaagcgt cggtcgtcat   3120
tgaagcccat gtgcattcca cagtccagca tgacattctt gcccgcaatg gagaccagga   3180
tgcagcttcg gcccacgtcc tggccggccc ccaagggcgt gactctgatc tcaggcatcg   3240
tctccgccgc gctcccggac ccgcgaggcc tcctgcggct cgagactagt tctctctctc   3300
t                                                                   3301

<210> 482
<211> 477
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (452)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (468)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (470)
<223> n equals a,t,g, or c

<400> 482
cggactcctg cgtgtattac agaacccaat agtatttatg gtcttcattg gcatcgcctt     60
caattttatt cttgatcgaa aggtacctgt atatgtcgaa aattttcttg atggacttgg    120
aaattctttt tctggatcag ccctatttta tcttggtctc acgatggtgg gaaaaataaa    180
gagactgaag aagtcggcat ttgtagtact aattcttctc atcacagcta aacttctggt    240
gctgccactt ctgtgcagag aaatggtgga actcttggac aagggcgaca gtgtggtgaa    300
ccatacaagt ttatcaaatt atgcatttct gtatggtgta tttcctgtag caccaggagk    360
ggcwactttg caacacaatt caacatggaa gtagaaatta traccccagg gtgggtgata    420
gcacattgtg tcggccccat cagtagttcg cnggtacgac ttccatangn ccaagcg       477

<210> 483
<211> 624
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (552)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (572)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (578)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (580)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (614)
<223> n equals a,t,g, or c

<400> 483
gcccacgcgt ccgggcgaac gcggttaccg tggaaaccgc ggccatggcg gcaccgcggc     60
aaatccccag ccacatagtg cgcctcaagc ccagctgctc tacagactcg tcgttcaccc    120
ggacgccggt gcccaccgtg tctctcgcgt cccgcgagct gcctgtctcg tcgtggcagg    180
tcaccgagcc gtcaagcaag aatctgtggg agcagatctg caaggagtat gaagctgagc    240
agcctccctt tccagaagga tataaagtca aacaggagcc tgtgattacg gttgcgccag    300
tagaggaaat gctttttcat ggcttcagtg cagagcacta ttttccggtt tcccatttca    360
ccatgatctc acgtacaccc tgtcctcaag ataaatcgga aacaatcaac ccaaaaacat    420
gttctcccaa agaatatttg gaaactttca tctttcctgt tctgcttccc ggaatggcta    480
gcctgcttca ccaagcgaag aaagaaaaat gktttgagag gaaaagaacc aawttcattg    540
sctgkgattt cngactgaat gggttataca antaagtngn tcgtgctgac tattcagtga    600
tcctaagaat tcantcgggt aatt                                           624

<210> 484
<211> 833
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (708)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (729)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (741)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (759)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (828)
<223> n equals a,t,g, or c

<400> 484
ggcacgaggg agcagggagc cgaggagggg ccaggggtgc ctgcggccac caccgaagac     60
cacattcagg tggaagcgag ggtcggaccc acggacggga ccccagaacc ccaagtggag    120
ctcaggcccc gtgatacgag gcgcatcagt ctacgtttta gaagaaggaa gaaggagggc    180
ccagcacgga aaggagcggc agccatcgct gaggacaggg aggaagaaga gggggaggaa    240
gagaaagagg cccccacggg gagagagaag aggccaagcc gctctggagg aagagtaagg    300
gcggccgggc ggcggctgca gggcttctgc ctgtccctgg cccagggcac atatcggccg    360
ctacggcgct tcttccacga catcctgcac accaagtacc gcgcagccac cgacgtctat    420
gccctcatgt tcctggctga tgttgtcgac ttcatcatca tcatttttgg cttctgggcc    480
tttgggaagc actcggcggc cacagacatc acgtcctccc tatcagacga ccaggtaccc    540
gaggctttcc tggtcatgct gctgatccag ttcagtacca tggtggttga ccgcgccctc    600
tacctgcgca agaccgtgct gggcaagctg gccttccagg tggcgctggt gctggccatc    660
cacctatgga tgttcttcat cctgcccgcc gtcactgaga ggatgttnaa ccagaatgtg    720
gtggcccanc tctggtactt ngtgaagtgc atctacttng cctgtccgcc tacagatccg    780
ctgcgggtac cccaccgcat ccttggcaac tttcttacca agaagtcnat cat           833

<210> 485
<211> 979
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (923)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (947)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (957)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (970)
<223> n equals a,t,g, or c

<400> 485
ggcacgagag ctggagatgt tcacccttcc tcaaaaggac ttcagggctc ccaccacctg     60
tctgggcccc acctgcatgc aggacctggg cagtagccat ggggaagatc tggaaggaga    120
atgctccaga aaactggacc agaagctgcc agagctccgt ggagtgggtg atcctgccat    180
gatctcctct aatacctcct acctgtcctc taagaggaag aatgattaaa tggttctggg    240
gattcagctt gaggagggct acaggaccta ccacatggat gagtatgatg aggacaagaa    300
ccccagtggc atcattaayt tgggcaccag tgagaacaaa ctctgctttg acctgctgtc    360
ctggcggctg agtcagcgcg acatgcagag ggtggagcca tccctgctgc agtatgctga    420
ctggagggga catctgttcc tccgggagaa rgtggccaag ttcctgtctt tctactgcaa    480
gagcccagta cccctcagac cagagaatgt ggttgtcctg aatggtggtg cctcgctctt    540
ctctgctctg gccacggtgc tgtgtgaggc cggggaggct ttcctgatcc ccacccctta    600
ctatggcgct atcacacagc acgtgtgtct ctatggcaac atccggctgg cctatgtcta    660
cctggacagt gaggtaagag tcttgacttc ctaggtggaa cctgggcctg cctgtagtca    720
agagtttcct gagtctgaat ttgagggtgg tccatgctga gggctctggg gttgtgatga    780
gtagggaatg gagccttctg ttgctgcatg gctgcctgtg cctgggttcc ccagtggctc    840
caaagttcca gtctctgaga tccctggggt tgatgtamaa gccaagagcc agacccagaa    900
acagcaaggt aggaacagag canggtagac ctaacatgac acccaanaag tgatganggg    960
gctctgaagn gatgggttg                                                 979

<210> 486
<211> 805
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (734)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (783)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (799)
<223> n equals a,t,g, or c

<400> 486
acccctccat ttctcgccat ggcccctgca ctgctcctga tccctgctgc cctcgcctct     60
ttcatcctgg cctttggcac cggagtggag ttcgtgcgct ttacctccct tcggccactt    120
cttggaggga tcccggagtc tggtggtccg gatgcccgcc agggatggct ggctgccctg    180
caggaccgca gcatccttgc ccccctggca tgggatctgg ggctcctgct tctatttgtt    240
gggcagcaca gcctcatggc agctgaaaga gtgaaggcat ggacatcccg gtactttggg    300
gtccttcaga ggtcactgta tgtggsctgc actgccctgg ccttgcagct ggtgatgcgg    360
tactgggagc ccatacccaa aggccctgtg ttgtgggagg ctcgggctga gcatggccam    420
ctgggtgccg ctcctctgct ttgtgctcca tgtcatctcc tgctcctcat ctttagcatc    480
cttctcgctt tgactatgmk gagctcatgg gcctcaaaca ggtatactac catgtgctgg    540
ggctgggcga gcctctggcc ctgaagtctc cccgggctct cagactcttc tcccacctgc    600
gccacccagt gtgtgtggag ctgctgacag tgctgtgggt ggtgcmtacc ctgggcacgg    660
accgtctcct ccttgctttc ctccttaccc tctacctggg cctggctcac gggcttgatc    720
agcaagacct ccgntacctc cgggcccagc tacaaaggaa aacttccacc tgctttttgg    780
ggncccagga tggggaggnc agagt                                          805

<210> 487
<211> 1728
<212> DNA
<213> Homo sapiens

<400> 487
gccgaaagca agtcaagttt taagcaggct ttggaagccc tgccccagct ttccagtgga     60
gcagataaaa agttactgga agagctcctg aacaagttca agagtagcat gcacttgcag    120
ctcacctgtt tccaagcagc ttcttcaacc atgatgaaaa cataaatatc tgccacataa    180
aagaagtcca ggaaaataac acgtaataag actgttcact ctctaagtac cctaaaggta    240
tttggtgtat taaacattgg gtttgccatt tttctctttt ttcttcctct gacttcgaaa    300
attgttggta tacatttcaa ccaaaatgac ctcatttgaa atgcccagga agtatttgtt    360
ttgccattct tactagatca gatcctgtat gactttaaaa tacattttaa aatatatttt    420
gcatctcagc agaaggttga gtgctgcagg aagagctgct tctgcaggga gttttctgga    480
atggcgtggc acatattgaa gcatttctca gtgtcccgtt cacggaagcg caggcagctc    540
ccacgacaca cggagagact gactgatacg agatttggaa agctatgtag acatctttgg    600
agctcttact gtcctaaact gtacagctgt gcttaaaacc ctyatttcat ataaatggcc    660
ttaagttttc taattcaagc gggtttttgg aaaaatttat ggtctccatt aaaatacata    720
ttacaactgg ggtagattat ttgtggtcca ggtgtctgtg atttaacttt gcgttttgct    780
atctgatttt tatttttcac agggctaagc atgagctttc attctcactc actcttaatt    840
tgtcgtgcgt cactacacat gcacgtgttg cagtccctga ggccctgtgt gttatctgtg    900
atggagtgtg aatgtgtaac gggcactgtg ttacactctc aggtgttggc ggggcggtcg    960
cagayttcag ggtcccctaa cggaaaggcc aggctccgcg tggacggcca actccctgcc   1020
cgctccttca gcaggtgact gtctctgcca cttcttacct gctgaaggat cttgctcagt   1080
agctggaaca atgctgctgt cacacagtct cttctctgaa acttcaggat gctccttggt   1140
caccaggcaa tgggagctgt agaccagccg catgcacttg ccccacattc actgctgact   1200
ggcttcactg gaataggttc aggtcaccgg gacttctctc agagtcagca gcccacccaa   1260
ctccctcata ccgtcgcatc tgaaaatttt cagagaggaa ttctctttgt agtcggcttg   1320
tcagggtttt caagtttttc tatggttatt tttaaatctc tttttttaaa tgctaaaatt   1380
aatgtcctca ttaatgcaag taattttaga gcacagtgta gccatgtaca gtttccatta   1440
tttaaaataa ataaatgtgt tggttcattt ggtgtatggg gggacatcat ggtaactgga   1500
aatgaaagtt taatctttca caaatgtgct tgataaagct gttaagaatt gtctttccta   1560
agtatgttaa ctgttgtatc taactcaact gtgagctaag tttaaaaact gcaatcatga   1620
atgtttgtga tattttaaat atctactaca gcacattcag ccaataaaga atctgccttt   1680
aatgtaagtt gtaatttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                1728

<210> 488
<211> 562
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (473)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (480)
<223> n equals a,t,g, or c

<400> 488
tcaccctcct ggccaattgt gttgcacctt gggnactgaa tcacatgagc cgtcgactaa     60
gccagatgct tctcatgttc ctactggcaa cctgccttct ggccatcata tttgtgcctc    120
aagaaatgca gaccctgcgt gtggttttgg caaccctggg tgtgggagct gcttctcttg    180
gcattacctg ttctactgcc caagaaaatg aactaattcc ttccataatc aggggaagag    240
ctactgggaa tcactgggaa actttgctaa tattggggga gccctggstt ccctcrtgra    300
tgatcctaag catatattyt cgacccctgg ccctgggatc atctatggga gtctttgcca    360
tcctctctgg ccttgttgtc ctcctccttc ctgaaaccag ggaaccagcc tcttcttgac    420
agcatccagg atgtgggaaa atgaagggag tgaaatgagc ctagctgccc ctncagaggn    480
agcttctgtg gctattaggt ctgtggctga ggaaagcaaa acaaccattt tagggctacc    540
atcccccaaa aagggttaga tc                                             562

<210> 489
<211> 736
<212> DNA
<213> Homo sapiens

<400> 489
ggcacaggtg cactatttaa aggaagagag atggtgctgt ggtcgtaatg ccagaatgtc     60
agcatgtttg gcattggagc gggttgcagc tggccaaggg ctgcctactg aatcactctt    120
ctatcgtgcc tgttcttcag gatattatta aagattgtta tggcatcacc aaatgtgatc    180
ggcatgttgg taaaatttat tccaaatgtt cttcttttct ggattatgtc agacggtctc    240
taaagaagct tggattagat gagtccaagc tgccagaaaa aattataatg aactactacg    300
agaagtataa gcctcgaatg aatgagctgg aagcttttaa tatgttgaaa gttgtactgg    360
ctccctgtat agagactttg attcttctgg atcgactttg ttacctgaaa gagcaggaag    420
atattgcatg gtctgctctt gtgaagttgt ttgatcccgt gaaatctccc agatgttatg    480
ctgttattgc cctgaagaag cagcagtgat ttccattgaa gcaaattatt agatgtattt    540
ctctatgaga cctgttgctg agattgcttt tctaaacata tatgtcctgt tatacaaaaa    600
tttttaaatg actgttatgt attttaaata ataaaataat ggctaacaac agaaggttat    660
aatccatttt tccattgtca aagcatacat taataaaaga agaacctgtc ataataataw    720
aaaaaaaaaa aaaaaa                                                    736

<210> 490
<211> 1142
<212> DNA
<213> Homo sapiens

<400> 490
atgcaagtta cttttctcag taatttataa tttttagctc ttaattccca cagaagtcct     60
ttgagacact attattatcc ccagtttaca tgtgaggaaa ctgaggttct gagaagttaa    120
ataacttgcc tgaaatccac gtaactagca aatgatggag ccaggatttg accttagtca    180
ttcctgcttt ggagtctgtc ctcttaatac attatatggc gtctctaatt tgtgagtgag    240
tgaataagtg ttttgagatt ttaagtattt ataccacttg tactccactt ttgctggagg    300
tggattctag gcaggagtct gggatgcatt gaggatgtta atgaatttag caaatactca    360
ctgagcacct gctttatgtc agggatatga aagtgcttga cagacaaggt tcctgccttc    420
aaagagcata tgttccaggg gggaatctga cagtaaacaa gtaaacagac atggtaattt    480
cagattatca gtgctatgga gaaagttaac tgttacagta cattgcagag atgggttctg    540
taggcagtgt gtcacacaat gtttaatgtc atatagcttt catgatgttg gatattatct    600
cccccttttt ttttcttttc cttttttttt ttttttagac aggctctggc tctgtcaacc    660
aggctggagt gcagtggtgc aacctcagct tactacaaac tctgcctctc tggctcaagg    720
tatccacttc agactcccta gtagctggga ctgcaggcac acaccaccac acctggttaa    780
tttttttcca tattttgtag agacagggtc tcactttgtt gtccaggctg gtcttgaatt    840
cctgagctca agcaatctgc ccaccttggc ttcccaaagt gctggaatta caggtgtgag    900
ccactgtgct tggctcccaa ttttttttct aattaacccc acatctgctg aattaaagga    960
gagtgttaaa tacaaaaatg aatttattat gcaaatctgc agttatcgtg tatgttcttt   1020
tggacttgta ataagggagt atgttctagt attgaagaaa tagaaccaga gaggaatact   1080
gctgtaaaaw ttaaaaaaaa taatatagtt gatcggccgt gaatttagta gtagtagtcg   1140
gc                                                                  1142

<210> 491
<211> 536
<212> DNA
<213> Homo sapiens

<400> 491
actactgcat cattgttcag ctatcattgc ttgcacgtaa tttcatttac tgtgacactt     60
gcttctttgc agattttgca ttgacttgtg tgtacagaga tgaaatgtgc attctgaatg    120
ttgcatattt taaatttttc atgtgcagta tggctcggaa tatgtttggc cttttgcatg    180
tttctctaca aaagagaatt gagttacctc acagagaaca gatacatgga agtggactcc    240
ttgcctgtag agcctgcatg cttttttgtt tttttttgtt gttgttgttt tttcttaagt    300
tatatttgtt tttacttttt aaaaaagaag aggaaamaaa gccccctttt agaaactacg    360
tctgtcatac tgggagcttt atcactgcaa attggaaagc catcttatac aaaattattc    420
acatttttca tctacgattc aactaatcga agggattaaa ctaaagaaaa aactaagaag    480
aacatgaacc ttgactttga gaaattggta ttcmcgacat attattgggg tccatt        536

<210> 492
<211> 1248
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1132)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1158)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1247)
<223> n equals a,t,g, or c

<400> 492
aaatctttac cccgcaaccc ggctggatgg cgtttctgtt gcgtctggtg gtggcggtac     60
tggtgatgtc tggcgtgctt ttaggtatgt tacatatcat gccggagtgg tcattgggta    120
ccatgccctg gcgtttactg cgtttaatgg cggtcgtgct ggcggggatt gccgcgtact    180
tcgctgcact ggcggtactg ggcttcaaag ttaaagaatt tgcccgccgg acggtgtaac    240
aatgcattcc ggcctgcagt gcaggccgga gataatcttc agatcgaaat ctttttaccg    300
ccgcgatggg ttgttgaggt ctgaccgttc gccccatata gcgtcggttc ctgatgcggt    360
ttcaacattt ccagcgcctg ttgattgcgc tcaatctgtc cttccagtaa ccagccgtta    420
tgttgattca tttggcgtag ttgctgcgtt ttcacagtaa tttcctgcca gcgttgacta    480
atatcaacgc tatttgctgt attggttctt tcctggtaac tgttcgaggt aatccagcgt    540
cgccagcagt gagctttttt gttctgtaat ccattgcaac kggctgccgt tgatctgccc    600
catagagaga tgttgctgcy cytgawccat taccgtttkg agatcgttaa gcacasggga    660
catctggtcg aggawctctg cagacgtgtc atacgatcag ttactctgca agtcttgctg    720
cgcttcgttg atcagcgcat cggcaatttt gscgtgtcca tttttagttc accgttacga    780
atcgccagtt ttaacgcttc gacacgttca agattgatat cactgctgcc gggttgcatc    840
agttttgctt gcgcgtcgct taacgtcaca ctggtgctgg tggaggcggt tgtttttgcc    900
gcccggctgt tcgttaccgg cgcgtcagtg gtttcgcgcg gttgaacggt gcttacagct    960
tcagaggcga atgcgatcaa tactcatggt ttattcctca ttgagggcgc ttttatcatg   1020
tgttgcttat ttatcggcaa gggacgggta atctttaaca gcttacaggt ttataagaat   1080
attcccatct gcatcaacaa cgccgctgac tacctgtccc gataccatgc gnacccgcgc   1140
attctgtgcg acggctgnat tgttcagcgc ctgaccttct gcgttggcgc taaacccatc   1200
accgctggcg atcacattga cgcgttgtcc cgcttttacc cgcaagnc                1248

<210> 493
<211> 922
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (915)
<223> n equals a,t,g, or c

<400> 493
aggaaggacc tgctgatgaa tattacatca tataccgaaa tgtttttgat aaggtaatag     60
agcatatcac tgcatacaaa tccattctta cttcaatcaa aaaagaatat gatgccttta    120
ttgagacaat aaagaaagac cgaagaacta cattttgtct tcatggaaaa cttaaaggtt    180
tggcagcaga gcctacagct ttggtatatt acaggaaaag aacaatccaa cttgaagcaa    240
aaatgaggat tatcgaaagt aattcctcga agattcaatc tcaaatagat cacatcaagc    300
agtgtagggc agartatgac acaaaagaag taaaatattg gactttctsc aaagatcctt    360
caaaacctat tycaggcatg actcttcaag aatycatgaa tctagatgct ctcactaaat    420
acatgaaaca tcttgaagat aaatatgcag aaattaaaca agctatgttg ataaaatatg    480
tgccagctca gaggaaggct gatttagatg aagaaatgat tgtgttatta aaacggcgag    540
atgtagctga aaatctgaac aaaaaattgc agttttggtt taatgagtta atctcacttg    600
gtgaatatga aaaggcagct tgttatgcag caaacagtcc tagaagaatt cttcgaaaca    660
ttggtacaat gaatacattt aaggctgttg gaaaaattag aggaaagcct cttccattac    720
tcttattttt tgaggccctc tttatcacaa gtcatgcttt tccatgtcct gttgatgcag    780
ctctaaccct ggaaggaatc aaatgtggat tatcagaaaa acggttagat ttagttacca    840
attgggttac acaggaaaga tgacctgttg cagctattaa tgtcatgtcc ccaagtttga    900
attaattcaa tgtcncacta aa                                             922

<210> 494
<211> 2225
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2225)
<223> n equals a,t,g, or c

<400> 494
gagagaagca ctgaaaaatc ccattggatt tgtggaaaaa ctccagaaga aggctgatat     60
tgggcttcca tatccacaga gagttgttca attgcctgag atcgtatggg accaatatac    120
ccatagcctt gggaattttg aaagagaatt taaaaatcgt aaaagacata ctagaagagt    180
taagctagtt tttgataaag taggtttacc tgctagacca aaaagtcctt tagatcctaa    240
gaaggatgga gagtcccttt catattctat gttgcctttg agtgatggtc cagaaggctc    300
aagcagtcgt cctcagatga taagaggacg cttgtgtgga tgataccaaa cctgaaacat    360
ttaaccagtt gtggactgtt gaagaacaga aaaagctgga acattactca tcaaataccc    420
ycctgaagaa gtagaatcyc gacgctggca gaagatagca gatgaattgg gcaacaggac    480
agccaaamag tcttcaacaa gcagacgaca gcaccctctt aataagcatc tctttaagcc    540
ttccactttc atgacttcac atgaaccgcc agtgtatatg gatgaagatg atgaccgatc    600
ttgttttcat agccacatga acactgctgt tgaagatgca tcagatgacg aaagtattcc    660
tatcatgtat aggaatttac ctgaatataa agaactatta cagtttaaaa agttaaagaa    720
gcagaaactt cagcaaatgc aagctgaaag tggatttgtg caacatgtgg gctttaagtg    780
tgataactgt ggcatagaac ccatccaggg tgttcggtgg cattgcagga ttgtcctcca    840
gaaatgtctt tggatttctg tgattcttgt tcagactgtc tacatgaaac agatattcac    900
aaggaagatc accaattaga acctatttat aggtcagaga cattcttaga cagagactac    960
tgtgtgtctc agggcaccag ttacaattac cttgacccaa actactttcc agcaaacaga   1020
tgacatggaa gagaacatca tttactagtc ctcttcaaca catagcaatg gtatcattgt   1080
taattatgtg cacagtttgg aaagattctc tgctttccca gaaatgacac tcacagcatg   1140
agagcttcct gagtgttctc gtcaagtaca gctctgcacc gttgtggctc tagatcactg   1200
ttcagcagct gaacattcct ggtgagcaaa ggtttccctg gtgaattttt caccactgcg   1260
ttttaggtgg tgatcttaaa tgggtgagat ggaacgagag cacacattaa agagagagta   1320
aattccaaag gtttcaaaga acttggtcat aaatatgata atgagaagac aaagtattta   1380
tattaaaaca gtttagtagc cttcagtttt gtgaaaatag ttttcagcac agaaactgac   1440
ttctttagac aaagttttaa ccaatgatgg tgtttgcttc taggatatac actttaaaag   1500
aactcactgt cccagtggtg gtcattgatg gcctttagta aattggagct gcttaatcat   1560
attgatatct aatttctttt aaccacaatg aattgtcctt aattaccaac agtgaagcac   1620
tacaggaggc aactgtggca ttgcttcctt aaccagctca tggtgtgtga atgktataaa   1680
attgtcactc agatatattt tttaaatgta atgttatata agatgatcat gtgatgtgta   1740
caaactatgg tgaaaagtgc cagtggtagt aactgtgtaa agtttctaat tcacaacatt   1800
aattccttta aaatacacag ccttctgcct ctgtatttgg agttgtcagt acaactcatc   1860
aaagaaaact gcctaatata aaaatcatat atatggtaat aatttccctc ttttgtagtc   1920
tgcacaagat ccataaaaga ttgtattttt attactattt aaacaagtga ttaaatttag   1980
tctgcacagt gagcaagggt tcacatgcat tcttttatac tgctggattt tgttgtgcat   2040
catttaaaac attttgtatg tttcttctta tctgtgtata cagtatgttc ttgaatgatg   2100
ttcatttgtc aggagaactg tgagaaataa actatgtgga tactgtctgt ttatattaaa   2160
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2220
aaaan                                                               2225

<210> 495
<211> 1317
<212> DNA
<213> Homo sapiens

<400> 495
gttcatttct cttggagtag aattgctgaa tcctatggac gatttcctgt tcagtgtctc     60
cattttaagt gggattcttt gcagcatcct ggccgtgttg aagttcatgc tggggaaggt    120
tctgaccagt agagcactca taacagatgg gtttaactcc ctcgtgggtg gcgtgatggg    180
cttctccatt cttctgagcg cggaagtgtt caagcatgac tcggcggtct ggtacctgga    240
cggcagcata ggcgttctga tcggcctcac catatttgcc tatggggtca aactcctcat    300
cgacatrgtg ccgagggtga ggcagacacg tcactacgag atgtttgagt gaagggggcc    360
agcatccgca tgagaccatc gagatgagga gtttccacat aggcaaaggg tgccaatatt    420
taactgaaca tctggtttct ttttggaagt tttctttcac atggtttgtc attacaagac    480
aaggtctgcc cagccaggtg gatctacctt gcccccatca cctgccgccc ccatcaaaca    540
tgttgggaca atgcccatag gaatggacct ccttccccgt ctccagctgg gactggcgtt    600
ttttagtctc tggagtatga tkgttctcat gggtaggatg agatctttgg cagaaaggtc    660
ttcggtggtg ctctgagcct gcgctgcata ggactgagca gacccacctc ctccagcttg    720
ggtggccctg ccactccygg ttccaagtct ctccyttccy ggcaggtctt aagggaagat    780
tgtacccctc accctttaca tacccagaat catcagtatg tcacttccta atttctatca    840
gtgtatctca ttatttcata ctgttttact aatcctragt ctaaacagat ttgctcaaaa    900
ggagaccatt ctatttttta aagtacttag tgatacaygt ataagctttg catggacgaa    960
ttaaataagc acattgacct tttcttgtac attcagaacc tgaacatcca tgtgaaaact   1020
gggtccattt ttgagagatg tgaaactaca gtttatttgt aataaataaa tataatctat   1080
ccgtatatgc atatatctat atgctgtgtt aagtggtaat gggtacatta cagtctgtga   1140
gagatggatc gctccctctg taaggaacaa gacgttctca gctgatgtca cggtaggttt   1200
agattctgta gagtgttccc caacccgcac cgttctgtac ctctcacacc actgcttgcc   1260
cgggcagtag tggctgacca ataaagacct ttacctgttt tgtaaaaaaa aaaaaaa      1317

<210> 496
<211> 2433
<212> DNA
<213> Homo sapiens

<400> 496
agcctctttg gctcaaaagg gtgkgttatg aacgaacctc cttcagtcca actatccaga     60
cgttcattct ctctgccatt tggcacgggg tatacccagg atattatcta acgtttctaa    120
caggggtgtt aatgacatta gcagcaagag ctatgagaaa taactttaga cattatttca    180
ttgaaccttc ccaactgaaa ttattttatg atgttataac atggatagta actcaagtag    240
caataagtta cacagttgtg ccatttgtgc ttctttctat aaaaccatca ctcacgtttt    300
acagctcctg gtattattgc ctgcacattc ttggtatctt agtattattg ttgttgccag    360
tgaaaaaaac tcaaagaaga aagaatacac atgaaaacat tcagctctca caatccaaaa    420
agtttgatga aggagaaaat tctttgggac agaacagttt ttctacaaca aacaatgttt    480
gcaatcagaa tcaagaaata gcctcgagac attcatcact aaagcagtga tcgggaaggc    540
tctgagggct gttttttttt tttgatgtta acagaaacca atcttagcac cttttcaagg    600
ggtttgagtt tgttggaaaa gcagttaact ggggggaaat ggacagttat agataaggaa    660
tttcctgtac accagattgg aaatggagtg aaacaagccc tcccatgcca tgtccccgtg    720
ggccacgcct tatgtaagaa tatttccata tttcagtggg cactcccaac ctcagcactt    780
gtccgtaggg tcacacgcgt gccctgttgc tgaatgtatg ttgcgtatcc caaggcactg    840
aagaggtgga aaaataatcg tgtcaatctg gatgatagag agaaattaac ttttccaaat    900
gaatgtcttg ccttaaaccc tctatttcct aaaatattgt tcctaaatgg tattttcaag    960
tgtaatattg tgagaacgct actgcagtag ttgatgttgt gtgctgtaaa ggattttagg   1020
aggaatttga aacaggatat ttaagagtgt ggatattttt aaaatgcaat aaacatctca   1080
gtatttgaag ggttttctta aagtatgtca aatgactaca atccatagtg aaactgtaaa   1140
cagtaatgga cgccaaatta taggtagctg attttgctgg agagtttaat taccttgtgc   1200
agtcaaagag cgcttccaga aggaatctct taaaacataa tgagaggttt ggtaatgtga   1260
tattttaagc ttattctttt tcttaaaaga gagaggtgac gaaggaaggc aggaatgaag   1320
aagcactgcg tggcctccgg tggaatgcac ggggcacagc cgcgactctg caggcagctt   1380
cccccccatg ccagggctct gcgccgtcat gtgagactta aaaaaaaagt tgaatgactt   1440
cgtgatactt tggacttcta aattaaattt atcaggcata aattatgtag aattagaggc   1500
tttgaaaata atactggtag gttgctcaaa ggttttgaaa gagaaatcgc taggtaggtt   1560
actatctggc taatccattt cttatccttg acaatttaat tcatatttgg gaaactttta   1620
gggaaatgaa aaataaaagt cactgagtct gggtgacatt ttttaagaat aatataaatt   1680
cagtttcaaa ctcttctcac attaaaattt tgctgtgaac tcttactaaa atgagtttta   1740
rgttctgtaa gtggaaaaat gtgcttttat tttatgggcc atttttacca caactaatct   1800
tgccttggat tactaagcat ctcctgcgat cccacagagg actgtggtgg ccacaggagc   1860
tgaaagcaga agagtgggat ttratgccag gcagtggagt ggcctcagcc ccagattgta   1920
cctcctgccc tgtaggaggg gagggggcaa agccttctga cttcaccttt gtttgaccta   1980
tgtatggaac ttacttttac tttttgcctt aaatttttaa tgaaatgcaa attttctgtg   2040
atggggttct ctctctcttt ttttcggggg gtggagtcac taataaattt gcaaatgaag   2100
ttaaagacaa ggcaaccatc tggcttatgc tatataatac ttcatttaaa gaagaaagga   2160
aaagcaaatg cacttgcarc ttttgaggtc tcagcaaaaa tgggcatgtg tcttttttga   2220
agtttagaaa tatcctaatc tatttttatt tatctaaaag taagtgtttt ccggctgata   2280
aggctaaccc tacccaggaa aggattgata actaaataaa tttcctctgt tttcccatgc   2340
attgaaatta tgttggctga gccactgcac ccagcttttg ctggaagttt gattagcttg   2400
ggttgaatct gtagaacaag ttaagaagaa ctg                                2433

<210> 497
<211> 834
<212> DNA
<213> Homo sapiens

<400> 497
ggcactcggg ccgagccatg caggcggcgc gcgtggacta catcgctccc tggtgggtcg     60
tgtggctgca cagcgtcccg cacgtcggcc tgcgcctgca gcccgtgaac agcaccttca    120
gccccggcga cgagagttac caggagtcgc tgctgttcct ggggctggtg gccgccgtct    180
gcctgggcct gaacctcatc ttccttgtgg cttacctggt ctgtgcatgc cactgccggc    240
gggacgatgc ggtgcagacc aagcagcacc actcctgctg catcamctgg acggccgtgg    300
tggccgggct catctgctgt gctgcggtgg gcgttggttt ctatggaaac agcgagacca    360
acgatggggc gtaccagctg atgtactcct tggacgatgc caaccamacc ttctctggga    420
tcgatgctct ggtttccgga actacccaga agatgaaggt ggacctagag cagcacctgg    480
cccggctcag tgagatcttt gctgcccggg gcgattacct gcagaccctg aagttcatac    540
agcagatggc gggcagcgtt gttgttcagc tctcaggact gcccgtgtgg agggaggtca    600
ccatggagct gaccaagcta tccgaccaga ctggctacgt ggagtactac aggtggctct    660
cctacctcct gctctttatc ctggacctgg tcatctgcct cattgcctgc ctgggactgg    720
ccaagcgctc caagtgtctc ctggsctcga tgctgtgctg tkgggcactg agcctgctcc    780
tcarttgggc atccctggcc gctgatggcg ctgcggcagt gggcaccagt gact          834

<210> 498
<211> 4209
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2558)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2617)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2950)
<223> n equals a,t,g, or c

<400> 498
tttttttttt tttttttttt tttttttttt tttttkttaa aatgaaaatg tttatataaa     60
ttaacccatc cagtttaaag tagatttgct atgcttcact tacttaagga agaatatata    120
cttcctatat taataaatca catcaaataa gtaggaagtt tcaataacaa gcctgtagat    180
acattgaaac ccctttttat attaaaagtt aaaatgaaag acaaatccag attgaacata    240
gtgattgcaa aatataatgc aattttcaac aattaaaatt atgaaaatat acaaaattga    300
tgggcaacac aactaggcat ttgtacattt tccattatgt ggagaacact acaagtttct    360
ctacctttta tctacatcag ataaatgatt taaaccaaat gtttgctttg gagagtctta    420
acttaggatc tcagtagtat aaaaagcaat aatttttcag tctgtaaaca gtagtcgtga    480
tttttctcct ttcctttttt aaatatcagt ttaccacaca aaaacaaaca aaacaaaaaa    540
acccatacaa atcaaaaaca gcagcagcag caatgggtta tttgggaatt ctcttcaaat    600
accaatggca tacgattgct gggagagggt gctttttact catgtaagaa tatatatata    660
tatatatttt tttaactgta cacaatttat agtacatgag ggtttccaaa agaacagatt    720
gataagagat attggccatt tctgcataat ttcattcttt ttacaattat ctcaaaatgt    780
gaaagctgga tctaattgaa atgctacatt tagtaggaaa atcagcaaat aacaaaggaa    840
gcataacctc aacataacat tatttgtcat taaagccagt agaggtccca gatatcttta    900
ggcaagagac tggttaggaa gaccactaga gtcacacact gtccctgagg accaaggcta    960
gcccactgaa catacatatg ctagattgat catggtcagt cgatagactt tttcaaagag   1020
catttctaca gtacagtact tttttggata ttcagagaga catcatttca agaacacacg   1080
ccatacacat gtaccccacc ctccccagca gacacacaca aagttccatc ttaaacaggc   1140
catagtttta tgaaagaata tgttgtcatt acatgaaatt cagaattaac cacaattttc   1200
cattcatctt gttcaagaca gttcttcctt ttgggatagg gtatatgacc agctgttgct   1260
actcatatca aaaataaatt tttgaaatta gttgatggac taggatttcc aacaagcctt   1320
attttgaaca ggtaatgtag taattgttta aaatttcctt ggaagtttaa gcactgtatc   1380
aaattatgaa tctaagaaag tcaaaatgaa gggacaaaat gcaattactt tgcgtacaca   1440
gatattccca gctctcttgg ttgcttttaa aagaaaaaag taccacattt cactggagca   1500
gtgcaggttg gaaagcacct ttaaggtctt caagaccaat cctccattgg atgcttaatt   1560
tcctcatcaa attcatttct ttgctcttac agaattaaac ttgaactata tttaggtaac   1620
agaccaaaaa cagaagcagg gatttaaaca gaaaaatatt atcaaagaaa ctgcataaat   1680
tgtaggacat tttcaagagc aatttttacc tcttctatca gaccaaccac tgatagaaga   1740
agctagagtc ttggggacat ccaggtgaac aaagtaaaca ccatcctgtt ataattctct   1800
aagtttgaag aaagtagtcc aaacctcaaa cccactgaat aacatttctt ttgccagcct   1860
aaaacttaaa gcctaaggct aaatccataa tattacattc cttccttccc aaacccccca   1920
cacttaaaac attaaagtat taaatcttaa ttttcaagtc atatatatat gtgtatatat   1980
atatatgtat atatatgact cacaaaacca atgaaataag tatcatactt gcctgcataa   2040
attatgtgca cctctcttct ttgaaacagt cattcctatc tttcccaaat gtatgaaaga   2100
cagaaagcta gtcctcagcg ggcttaataa gtggtctgca ctgctttccc ctctaaacag   2160
ctataaatta acagagcctt ccttgccttc ttacctgaga tttttaactc tcacagaagc   2220
taggatgggg atgtcttaac tatcagacaa aaactagcca aaaactaagt gcctgtggtc   2280
atccaagtgg tgcccttcta ttgcgggtgc atatgccaga tctcatctaa ggtcctttgt   2340
gtacctgcct tgggttctgt gggagccaag tagctgagaa agcctcaaaa caaacttact   2400
gctgtgaaaa gggggtctgt tcccaggcat ggtctcccct ccacttcttg tggctcaagg   2460
accagaccaa aaactctcaa tgttatttat aatggaaggg ctattcagtt gctatgaggt   2520
tgatgcttta tgcttaattt ctattgctgt ttttatanac cccccgctcc cctgaaaaga   2580
tgtttctggt gatgggaaga agaaaagtag ggttctnttg ttgctgccat atgcatatgr   2640
acatgtataa aaagtggtca aacccagatg agggtcccgc ttctggttta tatacaataa   2700
tttaatcagt tgtatatatt taacacctaa aaaaattcac gatcaaagtc cttcatgcat   2760
tttatgagga agttctggat taaaatcatg gtcaaccaga tgttgctttt gcctgggaag   2820
atggtgtcat attctgttgc agagtcatca gtgcccatga tagatacttc cttaaatttt   2880
tagtttcttt gtggtctcaa gtcttttttt cagcagctcc cccatttcca gaagtgagtg   2940
cagataactn tctgcacctt cccttgcaca gtctttgaaa attttctctc ttccggtgag   3000
agagaagtgt cttctaaaat aagttcttca agtttaagtg caattagatg tgtttcaagc   3060
cctttaatat gatccacaac attggaaatt aaagtctgaa gcccagtaac atagtcttgg   3120
aaactggtaa agacaggtgg catgatgatg ctggtttctt ttttcttytt tttytttttc   3180
tgtaaattta gtttgtatgg tcgtaggaca ctctcacagt aactggatac ccaaaggata   3240
acagaaatag tctcaacaaa gaaaactaga ttttctaaaa gagtaggatg tgttttcaag   3300
ttaccatctt taacttctaa gaggtcacct ttacatttac tgaagacatc ttttaactgg   3360
tctagtaaag acttaaaact attttctatt cgttcctgaa tctccattgt atcctctaaa   3420
ccactggtat ccagctcata aatatcattg acaagataaa aagagcttat ctggcactga   3480
gaacagccag aattaaagaa tccacccatt ctggtaggta caggaccaag gaaaggatac   3540
tgaatatcct tctcaataaa tcgctttcct gtctccaggg ttgcctccag ctgttgaagg   3600
agcaaacgaa gaatatcaat ccgggagata ccccattctc ggcagtcttc tccgagttct   3660
ttggctccac agggtggttg agacttggaa gtccacttat cagcctcaat gttaaggatc   3720
ggattcttaa ccacaaggtc tcctcctcta aggaaagttt cttatgttct tcagaaacgt   3780
ccctgtcttt tggatcccag ctgaaaaaaa catttaagtc tctgttgtct cgcaaatctt   3840
cccatggaat gtcatcttct tctggcctaa ggttcattga ctttatactt tctgctaaac   3900
tggttgatmt atttgcttca agtagaaggt ctaacagcat ccgttcagta cggacttgtg   3960
caaaatgaag agaattattc agcctgttcc taaaagcgat aaactctggg atcttctcaa   4020
atgcaccata tttgtaagct tgaataatat attctgaggt mctctgatat acagccttgc   4080
agggttcatt tcaggccgcg ggattgcgcc acgggcgcta attcaactgc attcgatgcg   4140
gcttttaaac ccccatggga cacctcggcg agctgtttgc ctgcagtatc tggagaaatt   4200
aaagacgga                                                           4209

<210> 499
<211> 612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (588)
<223> n equals a,t,g, or c

<400> 499
ngagnganat cnctctatya tttgktataa aggacaagac ctgcctcacc ccaagtccat     60
gcttcaggcc actgctgaag ccaacaactt agcagctgca gcctctgcca aggacattta    120
ttataacaac atggaagagg tttgtggggg agagaaacct tatttgtctc cagacattct    180
agaggagaag cactgtgaat tcaaacaact tgctctggac cattttaaga agaccaagaa    240
gatgggtggg aaggatttca gctttcgtta ccagcaggag ctggaggagg aaatcaagga    300
attatatgag aacttctgca agcacaatgg tagcaagaac gtcttcagca ccttccgaac    360
ccctgcagtg ctgttcacgg gcattgtagc tttgtacata gcctcaggcc tcactggctt    420
cataggtctt gaggttgtag cccagttgtt caactgtatg gttggactac tgttaatagc    480
actcctcacc tggggctaca tcaggtattc tggtcaatat cgtgagctgg gcggactatt    540
gattttggtg ccgcatatgt gttggagcag gcttcttctc atatcggnaa ttccactcag    600
gccactgtga gg                                                        612

<210> 500
<211> 1149
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1133)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1134)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1144)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1149)
<223> n equals a,t,g, or c

<400> 500
cttaagctcg ctctccaaaa ctgctgcccc cagctgtggc aacgacactc ggccagagac     60
cgtcaatgtg cccgcgtgct ggccgacgag aggtctccna cagccagggg cttccccgca    120
agaggacatc gccaacttcc aggtgctggt gaagatcttg cccgtcatgg tgaccctggt    180
gccctactgg atggtctact tccagatgca gtccacctat gtcctgcagg gtcttcacct    240
ccacatccca aacattttcc cagccaaccc ggccaacatc tctgtggccc tgagagccca    300
gggcagcagc tacacgatcc cggaagcctg gctcctcctg gccaatgttg tggtggtgct    360
gattctggtc cctctgaagg accgcttgat cgacccttta ctgctgcggt gcaagctgct    420
tccctctgct ctgcagaaga tggcgctggg gatgttcttt ggttttacct ccgtcattgt    480
ggcaggagtc ctggagatgg agcgcttaca ctacatccac cacaacgaga ccgtgtccca    540
gcagattggg gaggtcctgt acaacgcggc accactgtcc atctggtggc agatccctca    600
gtacctgctc attgggatca gtgagatctt tgccagcatc ccaggcctgg agtttgccta    660
ctcagaggcc ccgcgctcca tgcagggcgc catcatgggc atcttcttct gcctgtcggg    720
ggtgggctca ctgttgggct ccagcctagt ggcactgctg tccttgcccg ggggctggct    780
gcactgcccc aaggactttg ggaacatcaa caattgccgg atggacctct acttcttcct    840
gctggctggc attcaggccg tcacggctct cctatttgtc tggatcgctg gacgctatga    900
gagggcgtcc cagggcccag cctcccacag ccgtttcagc agggacaggg gctgaacagg    960
ccctattcca gcccccttgc ttcactctac cggacagacg gcagcagtcc cagctctggt   1020
ttccttctcg gtttattctg ttagaatgaa atggttccca taaataaggg gcatgagccc   1080
ttcctcamra aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aannaaaaaa   1140
aacnaaaan                                                           1149

<210> 501
<211> 579
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (459)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (572)
<223> n equals a,t,g, or c

<400> 501
ctggaacaag gacctaagac tgctctttga ccagtttatg aagaaatgtg aagatggctc     60
ctggaaacgt ttgccttcat ataaacgtac acctactgaa tggattcaag acttcaaaac    120
ccattttctt gacccaaagc ttatgaaaga agaacaaatg tcacaggccc agctcttcac    180
cagaagcttt gatgatggcc tgggctttga atacgtgatg ttctacaatg acattgagaa    240
aaggatggtt tgcttatttc aaggaggccc ttacctggaa ggaccacctg gattcattca    300
tggaggtgcc attgcaacca tgattgatgc tactgttggt atgtgtgcaa tgatggctgg    360
gggaatcgtc atgactgcca atctcaacat caattataaa agacctatcc ctctttgttc    420
tgttgttatg ataaatagcc aacttgrtwa aagttgaang gaaggaaatt ttttggtttc    480
ctgtaatgtt cagagtgttk gatgagaaga ccctatacty cagaggsgrc aagyttattt    540
wtaaagscga atcccggcta aaaagtctga cnataaagg                           579

<210> 502
<211> 2292
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2236)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2247)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2252)
<223> n equals a,t,g, or c

<400> 502
gggtcgaccc acgcgtccgc aatatctgga gtacagaaag cagaaaatgg accaattgac     60
tggagtggag acatgcctgt ttcttgcagt ctttctcggg gtcttcaggt tctacttacc    120
cctgttcttg caaacatcct tgaagcagat caggaaaagt gttggggttt tgaccagttt    180
tttgcagaaa ctagtgatat acttyaccga atggtaattc atgttttttc gctacaacaa    240
atgacagctc ataagattta tattcatagc tataatactg ctactatatt tcatgaactg    300
gtatataaac aaaccaaaat tatttcttca aatcaagaac ttatctacga agggcgacgc    360
ttagtcttag aacctggaag gctggcacaa catttcccta aaactactga ggaaaaccct    420
atatttgtag taagccggga acctctgaat accataggat taatatatga aaaaatttcc    480
ctccctaaag tacatccacg ttatgattta gacggggatg ctagcatggc taaggcaata    540
acaggggttg tgtgttatgc ctgcagaatt gccagtacct tactgcttta tcaggaatta    600
atgcgaaagg ggatacgatg gctgattgaa ttaattaaag atgattacaa tgaaactgtt    660
cacaaaaaga cagaagttgt gatcacattg gatttctgta tcagaaacat tgaaaaaact    720
gtgaaagtat atgaaaagtt gatgaagatc aacctggaag cggcagagtt aggtgaaatt    780
tcagacatac acaccaaatt gttgagactt tccagktctc agggaacaat agaaaccagt    840
cttcaggata tcgacagcag attatctcca ggtggatcac tggcagacgc atgggcacat    900
caagaaggca ctcatccgaa agacagaaat gtagaaaaac tacaagtcct gttaaattgc    960
atgacagaga tttactatca gttcaaaaaa gacaaagcag aacgtagatt agcttataat   1020
gaagaacaaa tccacaaatt tgataagcaa aaactgtatt accatgccac aaaagctatg   1080
acgcacttta cagatgaatg tgttaaaaag tatgaggcat ttttgaataa gtcagaagaa   1140
tggataagaa agatgcttca tcttaggaaa cagttattat cgctgactaa tcagtgtttt   1200
gatattgaag aagaagtatc aaaatatcaa gaatatacta atgagttaca agaaactctg   1260
cctcagaaaa tgtttacagc ttccagtggg aatcaaacat accatggacc ccaatttatc   1320
caagttctaa cacattagta gaaatgactc ttggtatgaa gaaattaaag gaagagatgg   1380
aaggggtggt taaagaactt gctgaaaata accacatttt agaaaggttt ggctctttaa   1440
ccatggatgg tggccttcgc aacgttgact gtctttagct ttctaataga agtttaagaa   1500
aagtttccgt ttgcacaaga aaataacgct tgggcattaa atgaatgcct ttatagatag   1560
tcacttgttt ctacaattca gtatttgatg tggtcgtgta aatatgtaca atattgtaaa   1620
tacataaaaa atatacaaat ttttggctgc tgtgaagatg taattttatc ttttaacatt   1680
tataattata tgaggaaatt tgacctcagt gatcacgaga agaaagccat gaccgaccaa   1740
tatgttgaca tactgatcct ctactctgag tggggctaaa taagttattt tctctgaccg   1800
cctactggaa atatttttaa gtggaaccaa aataggcatc cttacaaatc aggaagactg   1860
acttgacacg tttgtaaatg gtagaacggt ggctactgtg agtggggagc agaaccgcac   1920
cactgttata ctgggataac aatttttttg agaaggataa agtggcatta ttttatttta   1980
caaggtgccc agatcccagt tatccttgta tccatgtaat ttcagatgaa ttattaagca   2040
aacattttaa agtgaattca ttattaaaaa ctattcattt ttttcctttg gccataaatg   2100
tgtaattgtc attaaaattc taaggtcatt tcaactgttt taagctgtat atttctttaa   2160
ttctgcttac tatttcatgg aaaaaaataa atttctcaat tttaatgtaa aaaaaaaaaa   2220
aaccgagggg ggccgnacca tcgccanagg ancgatacat ccggcgcgtt acacgcggac   2280
tggaacctgc ta                                                       2292

<210> 503
<211> 809
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (780)
<223> n equals a,t,g, or c

<400> 503
tctggacttg gtgcctcttt ctgttatatg ctttcctatt tagttgggag accagttgta     60
tacaaatacc taacagagaa agcagtaaaa tggtcacagc aggttgaacg tcatagagaa    120
catctcatta actacattat atttttgaga ataacaccat ttctgcctaa ttggtttatt    180
aatatcacat ctcctgtgat aaacgtgcca ttgaaagttt tttttattgg tacttttcta    240
ggtgtcgcac ctccttcttt tgtagccatt aaggcaggaa caacactgta tcaacttaca    300
acagcaggag aagctgtttc ctggaactca atatttattc tgatgatctt ggctgttctt    360
tctattctgc cagccatctt ccaaaaaaaa ctaaagcaga aatttgagta aaaataatca    420
tctgattttw agttttgctg tcatcaccat ctcaggatta acagctgcga ctttaggtgg    480
ggtatatttt cttctcctaa gagaatagac agtttttcca gattcatcat cattgactgt    540
caagaaagga cccttcagca aggctgtacc ctcaatgcag ttgatggcct gtcttcacgg    600
atttacagac ttggcctgat gcccatgtaa attcaagctt tggcttgtgg taacaaccac    660
aagaagacaa gcatctgtgg tgcggaggca agcaggctaa ctaggagttg acaagctaag    720
aaagtgaaac tgttctttct tagttaactg tctttctctg gagctctgtt attttgagtn    780
taatatttcc acgacactta gtaaatgca                                      809

<210> 504
<211> 2683
<212> DNA
<213> Homo sapiens

<400> 504
ccgaattccc gggtcgaccc acgcgtccgg agactgaaaa tatgatggac cgaattgtga     60
ctggcttgtc tgagtctagt gwcaaggtgc ggttagctgc cgtcagatgt ttgcacagyt    120
tatccagatc tgtgcagcag cttcgaacca gtttccagga tcatgctgtt tggaaacctt    180
taatgaaggt tttacaaaat gcaccagatg aaatcctagt ggtagcatct tccatgctgt    240
gtaatcttct tcttgaattt tctccaagca aagagccaat tttggaatca ggagccgtag    300
agctactttg tggattaact cagagtgaaa atcctgcttt acgagtgaat ggaatttggg    360
ctttaatgaa tatggcattt caggctgaac aaaaaataaa agcagatatt ttacgaagct    420
tgagtactga acagctattc cggttattat cagattcaga tttgaatgtg ctgatgaaga    480
cattgggact tcttagaaat ctcctctcca ctcgtcctca tatagataaa ataatgagta    540
ctcatggaaa gcaaattatg caagccgtca ctcttattct agaaggggaa cataacattg    600
aggtcaaaga gcagacactg tgcatcttag ccaacatagc ggatgggaca acagcaaaag    660
atcttattat gaccaatgat gatatcctac agaaaatcaa gtattacatg ggccattcac    720
atgttaaact gcagcttgca gccatgtttt gtatatcaaa cctcatatgg aatgaagagg    780
aaggttcaca agaacgccag gataaattac gagacatggg catcgtagat attctacaca    840
aactgagtca gtcaccagat tcaaaccttt gtgacaaggc aaagatggca ctgcagcagt    900
acctggcatg atgggagtgc ccctgggcac ctgcgagcat cccacctcct tgtttaagga    960
agtacaggaa ccagcctcat ttgattcctt ctatttgcac aagtcacctt ggactgcagg   1020
gagctgtttt gcaaaagcag tttagtaggc ttagatctca aattcatctt gagaacattt   1080
ttttgaggta gtaatttcct cagaagactc ttgtgttttg ttttggtttt tttttctgag   1140
ctactcggac tctttattag aacaatcaat cattttcctt tggacctaca atttttgcct   1200
atgctgcagc cactttgtga gtgagaatga atatgtctgt gtgaacacac aggcatgcgt   1260
gtgtatgtgc acgtacatgg gccagaatga atggatgtgt gtgtgtgagg gatacctcag   1320
atttttcttt tcttattttg tgtgaaaatc tcttttctac agattttcca gggtttaagc   1380
attgcttgct gtataaaaaa ctttactgaa ttatatacag tttgaatgaa atgttatttt   1440
aaaaacaaaa caattgttaa gtgttccata aaggttatgt tgaattttgg tcagatgaat   1500
atttgtaagt aaaaaatata tgcatttctg aacctcaact tacatagatt ttctttatat   1560
aaaaaaaaag aaaaaaaaag aaaaagttgg ctatagttgg cctgattaac aggcactata   1620
catggtgctg tgcaaaatag taagctagca tcttactgcc gtcaatatta gcaggtacag   1680
agcctttttt catcctaatt cagtaagttc tcaggcttyc aagtcaaatg gagaagtaaa   1740
gtgaggcaac agattcacca taggcttttt gaagcatcaa agggaaatat aactactgat   1800
agtgaaagcc cagccatgac ccagatgggc ttacccttga caggaactgg ggaccaagag   1860
cctcccaatt gccctaactc ctgtcattgg tattagcaat atctggccag atttagaacc   1920
agtcatggaa acttgtgctc aaactaaaag taggtcatca cttcccagaa acagaatacc   1980
ttgtgcttcc tgaaacagca tatatcactg tgaaactaaa gaatattcta cagacacccc   2040
tgtagaaaga aacaaagaac aggatagttt agaaagcttt ctgttagctg tattcagcaa   2100
atttcatact agttgctcag gactgctagt tggtatgctt ttgtaaaacg agattgaaat   2160
ttaataaaag atgcaactaa aatctttcct gcatgaagct aaaagcactc aagttgagag   2220
aggggcaagg gaatctcccc aggatgactg aagatgactt ctttttacag caagtactgt   2280
tagcctttct gcacccctta gcttggcccc tgctccaact tctgggtcag cagcaaggtg   2340
aactcaacag aagttgctct tgactgtttg arggtagaag cagcctacct tttctctttg   2400
ctaaaagaag gtcaaagckt cgcaaccagg atgcaaggtc tgcggtccag aagcttgcgg   2460
tgagtgtgtg ccactgatgg agctccaagc ccacccacca gccactcctg atggggttgc   2520
tcacactgca gctgccctat caccaccctg cacgttcctt ggaagattta aatgtttggt   2580
tgcaaatgaa tgttttaaaa atgtatttaa tgcaattttt cctgctctca acatgaccac   2640
ccaagattca aacacaaaaa aaaaaaaaaa aaaaaaaaaa aaa                     2683

<210> 505
<211> 809
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<400> 505
cggggccccc cccngggttt tttttttttt tttttttttt tttttttttt tccacacaca     60
cagcctttat tgagcagcta ctgggcagtg acgctgccga ggcgggaatc ccaccacagt    120
cctgaccgca gctgggaccc ctttgcctcc tctgacaccc ccacctcaat ttgataccca    180
cttcctgagc aaatgtgacc cctagggcct gggattccca agaccacccc gaaatgcagc    240
ggccccaccg tctcctgagg ccggtgagcs agrggcagca gtgcrgctca gcaggtgcga    300
ggcaggctta ggatttcgga atcaccacct ggaacttaca gacgggcagg gctgccacgg    360
aggcggtgac cacgctctca atgcccaggg tatagagggc gccgcgcagg aggccgcagg    420
tgaaggccag gaacttgggt gcttcctcca gatactgcar gccagagscc atcgggagga    480
ggagggggaa gctgttgtct tgcaggacgt aggtcccctg gtgattggtg cgcaggctgt    540
ccatctgctt ctggaacacc gccacccaca ggtctttgca caagaacttg aggacatcca    600
gctcctccct gaaggccagc gtctcccggg gcagcctctc gcctagagcc tggcccacac    660
ggaaccccat accctccagg accgacaggc tcatcttctg tccccccggg ccggggtcgg    720
ggtcgtgagc ccacagctca gccaccatct ccgtgtgaag aaactcaaac aacacagtat    780
ccgccatgcc ccctcctcgc acctgtgcc                                      809

<210> 506
<211> 590
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (583)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (587)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (589)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (590)
<223> n equals a,t,g, or c

<400> 506
gcccggccta ttcccttggg cttttaaaaa gcgtcttgga tggaggtggt gcaggtgctc     60
accaagcccg cagtaaccca agttgcatgt atccccaggg cacttttgtg attcccctgc    120
ttgtgactgc acaccgggac cccactcaat tcaaagaccc agactgcttc aaccctacca    180
acttcctgga caagggcaag ttccagggca atgatgcttt catgcccttt gcctcaggtg    240
caggcagagg aggaagggga ccagcctgga ctggctctgg ggtacctggt gctcactgtg    300
cacctgtgta cccggcaaag cagatgtgcc tgggcacagg cctggcccac tcgggtatct    360
tcctattcct tacggccacc ttacagaggt tctgcctgct ccctgtggta cgccctggca    420
ccatcaacct cacctgcagt gcactggcct gggcagtgtc cccccagact tccagctcca    480
gccagtggcc tgctgaggtc aggctccact atggtgggct cactggccct caaacctcca    540
taccctcctc ggtcaataaa ggccctaaat tgcaaaaaaa aanaannann               590

<210> 507
<211> 1698
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<400> 507
cggacgcgtg ggnggacgcg tgggcggacg cgtgggggcc acgaaatacg agaggcaatc     60
cagcatccag cagatgagaa gttgcaagag aaggcatggg gtgcagttgt tccactagta    120
ggcaaattaa agaaatttta cgaattttct cagaggttag aagcagcatt aagaggtctt    180
ctgggagcct taacaagtac cccatattct cccacccagc atctagagcg agagcaggct    240
cttgctaaac agtttgcaga aattcttcat ttcacactcc ggtttgatga actcaagatg    300
acaaatcctg ccatacagaa tgatttcagc tattatagaa gaacattgag tcgtatgagg    360
attaacaatg taccggcaga aggagaaaat gaagtaaata atgaattggc aaatcgaatg    420
tctttgtttt atgctgaggc aactccaatg ctgaaaacct tgagtgatgc cacaacaaaa    480
tttgtatcag agaataaaaa tttaccaata gaaaatacca cagattgttt aagcacaatg    540
gctagtgtat gcagagtcat gctggaaaca ccggaataca gaagcagatt tacaaatgaa    600
gagacagtgt cattctgctt gagggtaatg gtgggtgtca taatactcta tgaccacgta    660
catccagtgg gagcatttgc taaaacttcc aaaattgata tgaaaggttg tatcaaagtt    720
cttaaggacc aacctcctaa tagtgtggaa ggtcttctaa atgctctcag gtacacaaca    780
aaacatttga atgatgagac tacctccaag caaattaaat ccatgctgca ataacaattc    840
tggaataagc acctgctgta gacagaagac agtattctgc aatgactgag aatgcagttt    900
tttagtgatt gcaattacta tctcatttat tcttgctttt atttctttcc tctgttcctc    960
ttccctcttt tttaatcatg ttcttaagac ttcttttctg tgccaaaatc agtaaagtta   1020
cactctgaag ggatatcatc ctttcaaacg ggccatctaa ggcagctaat tatgcattgc   1080
attggggtct ctactgagaa aaattctgtg acttgaacta aatattttta aatgtggatt   1140
ttttttgaaa ctaatattta atattgcttc tcctgcatgg caaaactgcc tattctgcta   1200
tttaaaaacc ctcaatgact ttattttcta ctgccgcctt tttcatgtgc aaccaaaatg   1260
aaaatgttta aattaactgt gttgtacaaa tggtacccaa cacaaacttt ttttaaatta   1320
gtaatacttt tgtttaaagt tttaagtttg cattttgact ttttttgtaa ggatgtatgt   1380
tgtgtgttta acctttatta actaacgtta aaagctgtga tgtgtgcgta gaatattacg   1440
tatgcatgtt catgtctaaa gaatggctgt tgatgataaa ataaaaatca gctttcattt   1500
ttctaagtgt ggcttggttt actgatgttt tgtttttagg cttctgaagt tttccccatg   1560
tatgttttta tggaatgcat atatacatta catgattttt tcttctttta ggggagagcc   1620
gggtcttttc attagaattt tgatcatcgc tccatgtata tacttttaat tgcctttaaa   1680
attttgctaa gtatcaaa                                                 1698

<210> 508
<211> 1582
<212> DNA
<213> Homo sapiens

<400> 508
gttcaacttt tgttttctac ccttctagac attttgtgcg tatatgtaca catatgtgag     60
tagtaaatga gcacttaatt agaataatag acctttctca ttagtatgag ttcttttact    120
tcctgtaaay aagcacacta aaaactttaa ttttttcaga tggactgagc tgtgtccaat    180
gattgaagcc aggaagaatc atgggctggt atttgtaaaa gacaagatat ttgctgtggg    240
tggtcagaat ggtttaggtg gtctggacaa tgtggaatat tacgatatta agttgaacga    300
atggaagatg gtctcaccaa tgccatggaa gggtgtaaca gtgaaatgtg cagcagttgg    360
ctctatagtt tatgtcttgg ctggttttca gggtgttggt cgattaggac acattctcga    420
atataatacc gaaacagaca aatgggttgc caactccaaa gttcgtgctt ttccagtcac    480
aagttgttta atttgtgttg tcgatacttg tggagcaaat gaagagaccc ttgaaacatg    540
aaaaatgagt ggacttcaga ctcatcagag actctaaaat atagccacca gtgctttgtt    600
ccaggagttt ggtgacaaag ttttggtttg gtgttttggt aaagaaagtt tcaagtgaaa    660
tgaggttcct ataaaataga tgtttctttt atatggrttt ccttaattca aagatcatat    720
tttagctggc cacaaaacca agaacatatc tagcaagaaa acttgaaaaa gtataagcat    780
ttgttaaaaa tgtgaatttc ttgaatgaat ttcacatttg taactatgat tttggcagaa    840
tagaagattg gctcatcagt gaagcgcagt atcttagctc tagattctat tttcatgcat    900
cacagaagtg ctatacggtt aggtctgttt gtgctcagtc aagaactaag aaatagtatg    960
aattgtaagt caagatgggc aactcagatg gagcagctta gtctcacagt ttgcttgtct   1020
atttatttta tttagtgcca aatgtattcc attttaaaag taagccagag tgagtcaagg   1080
catatacaca ctttctcaca aaacttccta aacagatttg ggggtttaat atgtccaact   1140
cctcatgaaa tatattcaat ccacttaaat atattccatc tttttaacat aaaatgtaaa   1200
gcttagcacc catcattaat ttatgtctct gttttatcca gtggttaaaa aaggattctg   1260
cctctttagt cctcactgtt aaataaaacc caatcatagt aagtgattaa ctagcaaaaa   1320
gtaaagctat ttatagcaaa tttctagatc attagaaaag cactggtagt tgtacaatat   1380
cagtgttgac tttgaacttc tttaacgaga tcatgaattc ttttccctta gccaaaacat   1440
gaaatattta acctagttgt ctctaaaagt tttgtaatca tgagttagat atatgtcatc   1500
tcctattcat tgcttttatg tgatcaataa atcttttaca aacccaaaaa aaaaaaaaaa   1560
aaaaaaaaaa aaaaaaaaaa aa                                            1582

<210> 509
<211> 1324
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1284)
<223> n equals a,t,g, or c

<400> 509
gacatgctga aggacatgtg ggtgtcccta gcacccatgc ccaccccgag atatgctgcc     60
acctccttcc tccgaggctc caagatctac gtgctggggg gacgacagca nagtacgcgg    120
tcaacgcttt cgaggtcttt gacatcgaga ctcgctcctg gaccaagttt cccaacattc    180
cctataagcg ggccttctcc agctttgtga ccctggacaa ccacttgtac agcctaggag    240
gcctgcggca aggtcgcctc taccggcagc ccaagttcct gcggacgatg gacgtgttcg    300
acatggaaca ggggggatgg ctgaagatgg aacgatcgtt cttcctcaag aagcggcggg    360
cagattttgt ggctggctct ctgagtggac gggtcatagt ggctggggga cttgggaatc    420
aacccactgt cctggagacg gcggaagcat tccacccagg gaagaacaaa tgggagatcc    480
tccctgccat gcccacaccc cgctgtgcct gctccagcat agtcgtcaag aactgcctcc    540
tcgccgtggg aggtgtcaac cagggtctga gtgacgcagt ggaggccctg tgtgtctctg    600
actcctagct gtctctgggc tcagtacctt tgccctggac catatcactt cactcttaac    660
atgaggaatg atcttgtcca agcagtcggg gctacttcca agaatgtcag ctcctgttag    720
caaccagtgg agtctggcct tgggctctaa gttgacctct ctatagctcc aaatcctacc    780
aatctcagaa aactgtaaga ggcacagatg actccaccag ctgcagagtg actctgaaga    840
gagtcttcac ttactgcaca ggcaaagaaa ggcacaggaa tatttcctac ctctccctcc    900
tgtgagtccc acctcccccc acccccatct ccaggaggca ggtagagcag ttctraccga    960
gaggatagac tgctgttgct gtctttcccc agctctgaac tagttttaag gtagcttagg   1020
atgaaaaatg gagaatgatt gggggttcca aaccacttty ttctcccttg gcttatatct   1080
cttcaccatt tggtggtcaa ctgtgggsct accctggacc tcatctactc agcgagaatt   1140
ggacatgaag ctagaggcag ctgccttgga agggaarttc aggctcactt ggacagsccc   1200
aggcccatgg saggaagaat cccytccctc cttkggggtc cctgatgggc awgtttgatg   1260
grrraaggaa ccaaatctcc ccancccctg ggttctgctc ccccacatct cttccctaat   1320
tccc                                                                1324

<210> 510
<211> 954
<212> DNA
<213> Homo sapiens

<400> 510
tttttttttt gtaaacatac acattactga aatgacagca acccacattg cagaggagaa     60
aagtctatta gctgtacagt ttacatttca atgcccaaac ttatttatat atttacataa    120
agatgctacc ttgattaatc aatgtctatt tgcatttcca catgtgaatt tcttcagttt    180
tgatattcca tatgaaggag ctacagtgaa aacacttttg aataaagcag tgaaccctaa    240
gaatcttatc ttgagatgag atgtgtgaac caccatttga atgttatttc tccctgctgt    300
gtacattagt ctggctgggt gttggtcaca gacatggatg cactgacggc tattcccata    360
accgagccag gcgggaaggg ggaaaaggaa gacattattt gtcaccaaca acccagtatc    420
ccaagtcaaa attctcaact atggccaaaa aggcctaaac tcgacccaca ggaactggct    480
ttctaactgg ttgacaaaca cgtaagctgc cctcctgcaa aagccaacca gagaacaggc    540
aggtggcaac aggacccagc ctagagcaga gcacttcaga agaggatgga taaatccatc    600
agggatgctc agggcttcct gaccactgtc ccgggtgaag gcactgccac attttctctc    660
aacaaatctg ttatgtccct ggatccaatt atttagccta aggaatgtca cctctgctaa    720
agagaagtgt gtttgtgagg ggtccaaaat gataaaccgt cttgttagca tcatgctcca    780
ccctctgagt taaccagctc agatccttgc tagattttgg aatccagtaa atctgtgttg    840
acccagaggt gctgctgcta atgcctccag agaattcgtg tccagatgaa gagacttaga    900
gtggcttctc catcctgctc gaacttcaat tgctctatct ccggtagtcc aaac          954

<210> 511
<211> 733
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (667)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (676)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (679)
<223> n equals a,t,g, or c

<400> 511
ctgtgaatta aaatatggag gctttgttgt gagaagaact actgaattaa ctgttacagc     60
ccctctgact gataagccac ccaagctttt gtatcctatg gaaagtaaac tgacaattca    120
ggagacccag ctgggtgact ctgctaatct aacctgcaga gctttctttg ggtacagcgg    180
agatgtcagt cctttaattt actggatgaa aggagaaaaa tttattgaag atctggatga    240
aaatcgagtt tgggaaagtg acattagaat tcttaaggag catcttgggg aacaggaagt    300
ttccatctca ttaattgtgg actctgtgga agaaggtgac ttgggaaatt actcctgtta    360
tgttgaaaat ggaaatggac gtcgacacgc cagcgttctc cttcataaac gagagctaat    420
gtacacagtg gaacttgctg gaggccttgg tgctatactc ttgctgcttg tatgtttggt    480
gaccatctac aagtgttaca agatagaaat catgctcttc tacaggaatc attttggagc    540
tgaagagctc gatggagaca ataaagatta tgatgcatac ttatcataca ccaaaagtgg    600
atcctgacca gtggaatcaa gagactgggg gaagaagaac cgttttggcc ttgaaatcct    660
acctganatg cttganagnc cttatggata taagtggtta tcccagattg agatttaatc    720
ccactggaac ata                                                       733

<210> 512
<211> 2590
<212> DNA
<213> Homo sapiens

<400> 512
ggggccccgc ccctgggccg tgcggtgacg ccacttcagg gccggcccgc ggaacttttg     60
ggcaggtgtc agcgcccgtg tcaccgccac gtcgcggaca tggtgatttc agaaagtatg    120
gatatactct tcagaataag aggaggcctt gatttggctt ttcagctagc tactcctaat    180
gaaatttttc tcaagaaggc actgaaacat gtgttgagtg acctgtcaac taagctgtct    240
tcaaacgccc ttgtgttcag aatttgccac agttcagtgt atatatggcc tagcagtgac    300
ataaacacca ttcctggaga actgactgat gcttctgctt gtaagaacat actgcgcttt    360
attcaatttg agccagaaga agatataaaa agaaaattca tgagaaagaa ggacaaaaag    420
ttatcagaca tgcatcaaat agtaaatata gatcttatgc tggaaatgtc aacctccctg    480
gcagctgtaa cgcccatcat tgaaagggaa agcggaggac accattatgt taatatgact    540
ttacctgtcg atgcagttat atctgttgct ccagaagaaa catggggaaa agttcgtaaa    600
ctcctggttg atgcaattgc ataatcaact aactgacatg gaaaaatgta ttttgaaata    660
tatgaaagga acatctattg tggtccctga accactgcac tttttattac cagggaaaaa    720
aaatcttgta acaatttcat atccttcagg aataccagat ggccagctgc aggcctatag    780
gaaggagtta catgatcttt tcaatctgcc tcacgacaga ccctatttca aaaggtctaa    840
tgcttatcac tttccagatg agccatacaa agatggttac attagaaatc cacatactta    900
ccttaatcca cctaacatgg agactggtat gatttatgtg gtccagggca tatatggcta    960
tcatcattat atgcaggatc gcatagatga caatggctgg ggctgtgctt atcgatctct   1020
gcagactatc tgctcttggt tcaaacatca gggatacaca gagaggtcca ttccaacaca   1080
cagagaaatt cagcaggctc tagtcgatgc cggggacaaa ccagcaacat ttgtcggatc   1140
gcggcaatgg attggatcta ttgaggtgca gctggtacta aaccaattga tcggtataac   1200
gtcaaaaatc ctgtttgtca gccaaggttc agaaattgcc tctcaaggac gggaactggc   1260
taatcatttc caaagtgaag gaactccagt tatgatcggg ggaggagttt tggcccacac   1320
aatactagga gttgcatgga atgagattac agggcagata aagtttctga ttctagatcc   1380
acattatacc ggtgctgaag acctgcaagt tattttggaa aagggctggt gcggatggaa   1440
gggcccagat ttttggaaca aggatgcata ctataactta tgtcttcctc agcgaccaaa   1500
tatgatttaa aatatcttgg agtcaaagac tgcagtagag tggtattata aatttgtgaa   1560
taaagaatca gtttaatttt tcacattaaa tcctggttct agtttgacca tttaaattat   1620
gacctttttc aaaggttgta aatactgcac ggagaatgta ttttttagac gttcctttaa   1680
taacttaaaa gacaaagcat acacaaccag catattatag gcatgtaaat acatgtgttc   1740
ttaaatggat cttcacttgg aagaaagttt ttcgtccttc tcagaaggag attagacaca   1800
acatatggta aagccaaaag caggagctta tagatttgca tgaaatgaag gcgttcttca   1860
gacttcttca taacccacgt gacatcagca cttccttttc ccactggtat tttctacact   1920
tccgagactc cgtttctgtc tgagcacggc aacacaatca ttcctgtcag ggtgttcact   1980
tgcttttatt gtctgcatac atttaattgt tgtaagaaac ttggcacagt ctggaaatcc   2040
acatgaccaa gcgagatctt cagctgtttg cccgttctta ttacataaat caatttgggc   2100
atcactggct acaagcaggc ttaggcactc caggcttcca acttttgctg ccttgtgtag   2160
tggagcttct cctaaaacat cctgctggtt gaggtcagcg cccgtttgca gctgccagag   2220
aagaaagcaa gcaaggcgct tcctgcggct aagtggacag gcgactgctt gcagggatcc   2280
gggggtgcgt tgaccgaggc ccctgtctcc agcaaatgct tcagaccatc cacctcgggg   2340
ttgcaatcca gcaacagcat ttcccgccta aggcagatga caagagtcct tggaagtgca   2400
gagaggtgag acactcgccg caccccgaca ggtaagaatg cgcaggctgg ccctagcacg   2460
ggagaattta aagaccgctg ggacttccgg gccggccctt ggcagccgcg ccccagctcc   2520
ggttacgccc gagcagccta atcctcaacg acccggaccc tgtccagccc cgccacggcc   2580
gcctcgtgcc                                                          2590

<210> 513
<211> 1301
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (371)
<223> n equals a,t,g, or c

<400> 513
gaccgacgaa tcagtgggca tgtgggcatc atcttcagca tgtcatacct ggaaagcaag     60
ggattgctgg ctacagcttc agaagaccga agcgttcgta tctggaaggt gggcgacctg    120
cgagtgcctg ggggtcgggt gcagaatatt gggcactgct ttgggcacag cgcccgtgtg    180
tggcaggtca agcttctaga gaattacctt atcagtgcag gagaggattg tgtctgcttg    240
gtgtggagcc atgaaggtga gattctccag gcctttcggg gacaccaggg acgtgggatc    300
cgggccatag ctgcccatga gaggcaggcc tgggtgatca ctgggggtga tgactccagg    360
catcggctgt ngcacttggt agggcgtggg taccggggat tgggggtctc ggctctctgc    420
ttcaagtccc gtagtaggcc aggtacactc aaggctgtga ctctggctgg ctcttggcga    480
ctgctggcag tgactgatac aggggccctg tatctctatg acgtcgaggt caagtgctgg    540
gagcagctgc tagaggataa acatttccag tcctactgcc tgctggaggc agctcctggt    600
cccgagggct tcggattgtg tgctatggcc aatggggaag gtcgtgtcaa ggttgtcccc    660
atcaacactc caactgctgc tgtggaccag accctgtttc ctgggaaggt gcacagcttg    720
agctgggccc tgcgtggtta tgaggagctc ctgttgctgg catcgggccc tggcggggta    780
gtagcttgcc tagagatctc agccgcaccc tctggcaagg ccatctttgt caaggaacgt    840
tgtcggtacc tgctgccccc aagcaagcag agatggcaca catgcagtgc cttcctaccc    900
ccaggtgact tcctggtgtg tggtgaccgc cggggctctg tgctgctatt cccctccara    960
ccaggtctgc tcaaggaccc tggggtggga ggcaaggctc gggctggtgc tggggcactg   1020
tagtgggtag tggtagtagt gggggtggga atgctttcac tgggttgggc ccagtgtcta   1080
ccctgccctc tctgcacggg aagcagggtg tgacctcagt cacatgccat ggtggctatg   1140
tgtataccac agggcgtgat ggagcctact accagctgtt tgtacgagac ggccagctcc   1200
agccagtcct aaggcagaag tcctgtcgag gcatgaactg gctagctggg ctccgtatag   1260
tgcccgatgg gagcatggtt atcctgggtt tccatgccaa t                       1301

<210> 514
<211> 614
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (589)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (598)
<223> n equals a,t,g, or c

<400> 514
cntatgggct ggagctactc ggccaagggt ttaagacttt aaatgagaat aaagggtggt     60
atttacgagg aaatgagagt gaataagtca tctctaacct ctcccagcct ttttttcata    120
agagagacca tattaaactt acatgtttga agactgcttc attctgcctc tagtaccagc    180
ggtttctctg ttctgtgatc aatgtgattc acaggaactc cttaagtaac aaacgaaatg    240
agccaggggc gtggaaaata tgacttctat attggtctgg gattggctat gagctccagc    300
attttcattg gaggaagttt cattttgaaa aaaaagggcc tccttcgact tgccaggaaa    360
ggctctatga gagcaggtca aggtggccat gcatatctta aggaatggtt gtggtgggct    420
ggactgctgt caatgggagc tggtgaggtg gccaacttcg ctgcgtatgc gtttgcacca    480
gccactctag tgactccayt aggagctctc agcgtgctag taagtgccat tctttcttca    540
tactttctca atgaaagact taatcttcat gggaaaattg ggtgttgcna agtattcnaa    600
gatctacagt tatg                                                      614

<210> 515
<211> 743
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (720)
<223> n equals a,t,g, or c

<400> 515
gctcatgctg cccctgacng agggctcgct gcggctgcgg gcggacgatg aggacagcct     60
gacttcagag gattccttct tctccgccac cgagctcttt gagtccctgc agactggaga    120
ttacccgatc ccactctcca gacccgccgc tgcctatgag gaggccctgc agctggtgaa    180
ggaggggaga gtgccttgcc ggaccctcag gacggagctg ctgggctgct acagtgacca    240
ggactttctg gccaagctgc actgtgtggc aggccttcga ggggcttctg gaagacaaga    300
gtaaccagct tttcttcggg aaagtgggcc gacagatggt gacaggcctg atgaccaagg    360
ctgagaagag ccccaaaggc ttcctggaga gctacgagga gatgctgagc tatgccctgc    420
ggcccgagac ctgggccaca acacggctgg agctggaggg ccgaggggtg gtatgcatga    480
gcttcttcga catcgtgctg gacttcatcc tcatggacgc cttcgaggac ctggagaacc    540
ctccggcctc ggtgctygcc gtcctgcgga accgytggct gtcagacagy ttcaaggaga    600
cggccttggc cactgcttgc tggtcggtcc tgaaagccaa gaggaggctg ctgatggtgc    660
ctgatggctt catctcccat ttctactccg tatcggagca tgtgagccct gtcctanccn    720
tcggcttcct tggacccaag cct                                            743

<210> 516
<211> 1805
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (254)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (313)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (427)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (430)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1803)
<223> n equals a,t,g, or c

<400> 516
cagaatctca gcacccacct gcttatcctc tatggtgtcc agggactgct gaccttcggg     60
tacctggtgc tgctgtccca cgttggcgag cgcatggctg tggacatgcg gagggccctc    120
ttcagctccc tgctccgaca agacatcacc ttctttgacg ccaataagac agggcagctg    180
gtgagccgct tgacaactga cgtgcaggag tttaagtcat ccttcaagct tgtcatctcc    240
caggggctgc gaanctgcac ccaggtggca ggctgcctgg tgtccctgtc catgctgtcg    300
acacgcctca cgnctctgct gatggtggcc acaccagccc tgatgggagt gggcaccctg    360
atgggctcag gcctccgaaa attgtctcgc cagtgtcagg agcagatcgc cagggcaatg    420
ggcgtancan acgaggccct gggcaatgtg cggactgtgc gagccttcgc catggagcaa    480
cgggaagagg agcgctatgg ggcagagctg gaagcctgcc gctgccgggc agaggagctg    540
ggccgcggca tcgccttgtt ccaagggctt tccaacatcg ccttcaactg catggtcttt    600
gggtacccta tttattgggg gctcccttgt ggccggacag cagctgacag gggagacctc    660
atgtccttcc tggtggcctc ccagacagtg caaaggtcca tggccaacct ctctgtcctg    720
tttgggcagg tggtccgggg gctgagtgca ggtgcccggg tctttgagta catggccctg    780
aacccctgca tcccactgtc tgggggctgc tgcgtcccca aagagcagct gcgtggctcc    840
gttacatttc agaacgtctg cttcagctac ccctgccgcc ccggcttcga ggtgctgaaa    900
gacttcaccc tgacgctgcc ccctggcaag atcgtggccc tcgtgggcca tctggcggag    960
gaaagaccac cgtggcttcc ctgctggagc gcttctacra cccacggcag gcgtkgtgat   1020
gctggatggg cgggacctgc gcacccttga ccctcctgct ccsgggccag ttgtcgcttc   1080
atcaccagag cccgtcctgt ttgggacgac catcatggaa aacatccgct ttgggaagct   1140
ggaagttcga tgaagaggtg tacacagccg cccgggaagc gaatctcacg agttcatcac   1200
cagcttcccc gagggctaca acacggtcgt cggtgaacgg ggcactaccc tgtctggggg   1260
ccagaagcag cgcctggcca tcgcccgagc ccttatcaag cagcccacgg tgctgatact   1320
ggatgaagct accagcgcgc tggatgcaga gtccgagcgg gttgtrcagg aggccctgga   1380
ccgggccagt gcaggccgca cggtgctggt aattgcccac cggctcagca ctgtccgtgg   1440
ggcccactgc attgtcgtca tggccgatgg ccgtgtctgg gaggctggga cacatgaaga   1500
gctcctgaag aaaggcgggc tatacgccga gctcatccgg aggcaggccc tggatgcccc   1560
gaggacagcg gccccaccgc ccaaaaagcc agaagkcccc aggagccacc agcacaagtc   1620
ctgagaaggg ccccctgagg tgtggtcgct gccaagcatc agtgttaggg ctggggctca   1680
gcctggggga gcctactggg actgagcccc caggagggcc agcatgtgga gagtcgctgc   1740
ggctgctcct kctcacaata aagccggggc cgagcagctg gcaggggagg ccaatccctc   1800
ccnat                                                               1805

<210> 517
<211> 638
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (573)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<400> 517
cgagacagaa caaaataaga ataatttttg tacacttaca aggctcagaa agaaaagaca     60
atkaaactca gcaaaaagag agaggagggg aggccagcca gcaccgtggg cagccgaccc    120
cttgcagcgc tggccagcgg ccgccaccac cacaccgcgg acacctagct agcagaccgg    180
tgtggcttgc tctttagggg tcatgcaaaa gaattatccc ccagaaaaaa aatccccaaa    240
ttatcccaga caggcagctc cgtggaggtg acaaggtgag agggagagga ggggaggagg    300
ccccaggacg ccagggtggc cggctgctgg gccacgtgct gtccgtggtg agccctgccg    360
ctgtcccatg gcccagggag ccactggtgc ggacccggca gatgtttacc ctgtgttcat    420
ggatggggac agctgtcctg gggcacagcg tggacggaag atggtgtcca ctctgagtgt    480
tcatcggtgg acagtcccct tggagtttag gatcctgtgt cctgttcccc attctgttgc    540
ccctcccttg gcttgatttk ttaggggaag atnaaagaaa atccttgttt gaaaacaatg    600
ttgaatttga aagtgggcag gcattngggc aggagcct                            638

<210> 518
<211> 2273
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (57)
<223> n equals a,t,g, or c

<400> 518
tttacggcgg ctgacccata aaatctacct agttctaaan ttctttaacc cacccantta     60
acaaaaacgg aggtaattag gtaaaacaaa aacgcccagg aaaagatcgc acttaaagga    120
acaaaagcac ccaaggagga aaaagaggcc tgagatttcc acggaattac aagtgaactt    180
cctgtcctgg gtaaacttcc ggaatcaaca acaggaagac ccaatcagaa tcttctccgg    240
gagccaatgg gagagcacat tacaaagagc aatcccagcg ccgctgtcac tgttatggtc    300
ctgtcagggt gccggcgtcg tggtgcttgg gtggtcgcca ccaagaagac tttggtgggg    360
tagtctcggg gcagctcagc ggcccgctgt gcccgtttct ggcctcgctc gcagcttgca    420
cgtcgagact cgtaggccgc accgtagggc gagcgtgcgg gtcgccgccg cggccgcctc    480
ggggtctggg cccagccgca gcctcttcta ccgcggccgg ttgggagtcg ccgcgagatg    540
cagcctccgg gcccgccccc ggcctatgcc cccactaacg gggacttcac ctttgtctcc    600
tcagcagacg cggaagatct cagtggttca atagcatccc cagatgtcaa attaaatctt    660
ggtggagatt ttatcaaaga atctacagct actacatttc tgagacaaag aggttatggc    720
tggcttctgg aagttgaaga tgatgatcct gaagataaca agccactctt ggaagaattg    780
gacattgatc taaaggatat ttactacaaa atccgatgtg ttttgatgcc aatgccatca    840
cttggtttta atagacaagt ggtgagagac aatcctgact tttggggtcc tctggctgtt    900
gttcttttct tttccatgat atcattatat ggacagttta gggtggtctc atggattata    960
accatttgga tatttggttc actaacaatt ttcttactgg ccagagttct tggtggagaa   1020
gttgcatatg gccaagtcct tggagttata ggatattcat tacttcctct cattgtaata   1080
gcccctgtac ttttggtggt tggatcattt gaagtggtgt ctacacttat aaaactgttt   1140
ggtgtgtttt gggctgccta cagtgctgct tcattgttag tgggtgaaga attcaagacc   1200
aaaaagcctc ttctgattta tccaatcttt ttattataca tttatttttt gtcgttatat   1260
actggtgtgt gatccaagtt atacatgaat agaaaaagat ggtgttaaat ttgtgtgtag   1320
gctgggaatt cttgctgaag gaattggaga aaacctgttg ctgcaaaatt ttacatgttc   1380
cagatggaaa gggaagtcta agcgcttttt aaaacaattt ttttttgtat ttaattaagc   1440
aattgcagtt atctgggatt tttgggtcag aattttaaat tctgtttgat tctccatatt   1500
ccagtgaata aaatacaaaa gcattgtgtt tttaagattg tgtcgatatt cacctaaaaa   1560
cttgtgccaa aagcacctgg attggtaatt atatttcact taaagggtaa atttgacaat   1620
atcttgataa tcaaaagtgc aatttttttc ttcaaaatgt tttctccagc atcacagatc   1680
ctgcagatat atatttatat ttatacatat atatttatga aataattctt actcacaaaa   1740
tatatttctg ataaacatta agatattaaa tctgatgcac aaacttttta atttggccat   1800
taatcttttt tatttaaaaa tttaaatttg tttttaaaat tgtatatagt ttttaaaatc   1860
tcacacatgc ttcgatactt ccttgttaag aattcttaat aactactaaa actgattttt   1920
aatagttgct gatatatatt tggtttgttt gggtatactt ttcaaaacca tttttgaatg   1980
tccaaacatc tgatttaaag tttctgttta tctttctgac caaaggagca agaggtataa   2040
tggatatggc attcattaaa atctttacta tgtacaaaaa cagtaatatt tacagcatca   2100
gtaaatattt ttaagtggta cttctaaatc ataaaagttg gggaaagaga cctttaaaat   2160
cttgtggtgt tgaacaatgt tatatgaagt agaaaaaata aaatacttcc cagttgtgtg   2220
ttttgtttta caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aac          2273

<210> 519
<211> 2295
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (483)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2291)
<223> n equals a,t,g, or c

<400> 519
ggctgtgaaa gggtttattt atctgtgggg gagggttgta tttttgaagt ctatttatta     60
tgtgcctgtg atgattatgt tcttttttag aggtggccgg ttatcagggt agagtctggt    120
gtgtactgtc gggcgcagag ggctccgcgr ygggagctga gcggaaggcg ckggctgcra    180
tctgctctct gttcccctgg atccgcctat gcacattacc cttgtttcat tactttttca    240
tgtcattttt ttatcccaaa aaatattttt taaaagttaa aaaaagacat atcaaacatg    300
caaatacttg aatccagcar gccaatagtg aaatgtgaac acttyctaat tctacacttc    360
caggttgaca tcagtacaca gaaacaggct ctaggaaaaa tttctaagtt catagcctac    420
gtgtgtgtat gtgtgcgtgt tgaaacagaa gtgtgtgtgt gtgtgcatgt gtggcgcgtg    480
ctncctcacg scgtgcagtt ttctgtgttt gtgtgtttga aagcgtgtga ggatttaact    540
gtgggttttc ccttgtattc agtatacgct ttttttttgg cgcattggtc aaacggttgt    600
tattattagc ttctaacttt gcactgagtg tcctcgccct tcctttagct aatcctatac    660
attacagaga attcctagga cagggctggc gacaattcat gtgtaaatgt ttactcaagg    720
actctgtgac tgcgtttaaa aagtacagtg tatatctctg gagaaataac atgtatacct    780
acctttagca gctttttatt gtggactaat gcaagaaaat tattaccaga gtattgcacc    840
atttttccat ttggaatata aagttaaaga gaaaaaaaaa aaaaaactgt tgttgaactg    900
tggccataga tacttgtaaa gaatggatgg ttccgtggaa ggaacagaaa caagcacttg    960
ggcgtgggtt gtgactgctt ttgggggagc ctggggtttg ggctcccacc tgtttacaga   1020
cctttttttc tccttcagac tttaaaattt taaaaattta aaaaggaatt aaaaaaaaaa   1080
aaagacttcc gtcgtaaaga aacctatttt cagaatgcag atgcgttcct tcagagctct   1140
gggacgggac agtgttgttc cctcggccat cgtcgtggac tctgtcgatt gctttcgccc   1200
cttcgtcaag gtgacaggcg ttgtggccac tgtcttgcac atgccggacg cgctctcagg   1260
aaagccaggg ctcccgaggg cagctccaca ccatttcatg tatttttaaa cccaactcct   1320
agcactgaag atgttattta aaaaaaaaaa aaacaaaaca aaacaaaaaa atgaaaaaaa   1380
agaaaaagag gaaaaaaaaa acacaaagaa gaaaaatacc taatctctaa tgtgtagcag   1440
ttacatattt accaaataat ggactcaaaa gaaatagatg tttgaagagt gctttatata   1500
ttaaaaattg ctttatgttt taaaaatgat caatgttttg attgttttgc aaggaagaaa   1560
gacaatggaa taacatacct tcaagtatgt tttaaaaaat atatatatga acattgtgct   1620
ccctgcctgc ttgatcagga aacttgtgca ttacattttt ttaattagct ttttaatggt   1680
tttatcaaaa caaaaaaaat acaaaaaaaa aaaaaaaagt cctgcaagac tgcagatcca   1740
caaaagctgg ttttatagag gatcatgaac tatgcacaaa ctgggttcaa gacttttttt   1800
ctcaagttta gtaggatatt tagaaaaacc arccttcctc agagtgactg catctcattg   1860
ccattacatg cgttctatat attcgatgga catacacctg cgtatgtata tccaatatgt   1920
gtgcgtgtga gcatgcgtgt gcgtatgtgc gtccgacata ccacttcccg tgctgccggc   1980
gagcattgag ttgtagaaaa actgttgttt taaaattggg gatggaagtc aagaatatgt   2040
ttgtttgttt ttgggttttg ttgggtttga ggggtttttt gtttgtttgt tttttgtttt   2100
ttttaccttt tattttgaac ttaatatgtc tgtaactctg agattaaaca acaagttcgt   2160
ggctcttaat gttttcctca tagaatgtga ctgttgaaga acatgcatcg aaagttgctt   2220
tcgaaagtac aacgctttat tgaatcttaa taaattgcaa tttttttctt ggcaaaaaaa   2280
aaaaaaaaaa ncccg                                                    2295

<210> 520
<211> 826
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (623)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (665)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (666)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (778)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (808)
<223> n equals a,t,g, or c

<400> 520
tctagccttc tcaaagccaa gtcccactat ttgctccatg aacagtaaca tctggcaaat     60
atgcattcag ttggaaggaa ttggccagtt tgcatatgca ctaggaaaag acttctgttt    120
gctcttgatg tcagcccttt atccagtact ggagaaggct ggagacyaaa ccctactcat    180
tagtcaggtg gytaccagca ccatgatgga cgtttgccgt gcttgtggct acgactccct    240
gcagcacctg atcaatcaaa attcagacta tttagtgaat gggatctctt taaatctgcg    300
tcatctggct ctgcatcctc ataccccaaa ggtcctggaa gtcatgctgc ggaactcaga    360
tgctaacctg cttcctttgg tggcagatgt ggttcaagat gtcttggcca ccctggacca    420
attttacgrt aagagagctg cttcctttgt cagcgttctg catgctctga tggcagcatt    480
agcccagtgg ttcccagaca caggtaatct tgggcacctc cargagcaaa gtttaggrga    540
agagggaagt catttgaacc aaagaccagc agctcttgag aagagcacca ccacagctgg    600
aagacatcga acagtttttg ctngaactac ctcaaagaga aggatgtggg cagatgggaa    660
atgtnntcgg attttgatta atgaagaaga ggaacagttc agtccctccc aaagtgggat    720
gagaatggac acccgttcca gattgtggag gccaccaatg gccattgcag attccaanta    780
ggccctggga cgtgatggga aggtggcntc cacttgttgg tcagat                   826

<210> 521
<211> 1785
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<400> 521
gatgattaat cactaaacag gtattgcata aaatagcaat tttcagctct ggattttggg     60
gaagggagta gaggctggaa atgtaggtgg agagtcaggc tggggagaga tgccacattc    120
gcaacattgg gttttttaca atagtactgc atctctgtag atccccgact ccagcctctc    180
ctcttgctgc ctctctcaac agtaacgatg ctgttactcc ccacgccaaa cctctgggct    240
ggccaggctc actccagccc cacagtcatt gccaggactg cctttgacct tacacagagg    300
aaacatcttc cacctgtcgg gagggarccg gggcggggat ttccatggca rarttactgt    360
tctctggtga tagagttctt tcakttttgc tacatggtct tgtggcaaag gactgggtgc    420
aggtgcagcc ttggttattt ctggaaacac ttctcctttt ctttwatttt gccagntctg    480
gctcatcagt caccttcctc tcagaaaggt gatttkggct cytctgccca gaccatcaaa    540
catttctgga ggtgtcacaa gcttccgtga ggttctggtc tctgcgaatt gcaggaagaa    600
tccaaacata ggaaaggggt gatgtgtatc agggtgtcca tcctcagctt tgctccacaa    660
agaccctcac acttgcacat tgttttgtta acagtattat ctctgagtag tgggtttatt    720
gtttttgctt acctgtttta aacacttctt caacaaactt gctttacttt ccatttttta    780
aaagtgtatt tcaatttttt attaataatg ccattttact cctgcaaaat ttctcactcc    840
ttcaaagtct gtgtatggca aagatcttcc taaccatcat tcaagttaga gcaactccat    900
ttctgtatca aaaagaaata cctttagtta ttgtctgaac ttgtcagaat ttctgagaac    960
gatgccagaa attctgtaat tgttttgtca cattaattga acaatgagag ggcaccagca   1020
ttcctcactc atgaggtaga agcaccacat ctacatttct ttttagctat gggtgatgtt   1080
tttgctttta aatcttagaa atctgttaat aaacaaataa cacaacaaag tttggggtac   1140
ttccttgtgg ggactgggat gcttaagcta aaacaaagtt taaatttgga ctgtgtgtgt   1200
tatgtttcgc agaatctata tgtttctcaa aagtgggtgt caccctcctt cctcccccaa   1260
cacacccttc aggggtaaga ggagaagtaa tgtagaaaaa ttaactgttt ctccactgta   1320
aaagtagggt gtctttagaa tgtttcatgt tcaaaggaaa gattgtgctt ctcccaaggc   1380
aaggtgttcc cttaaaaaaa aaaaaaaaag gttgagcatg tctttgtatt gctgtctctg   1440
gaagaggaaa tgaggcatct cttggggtga gaacaaggga gaattgaact ctcgggcctg   1500
gccagatgga ttcctcacac tggcacagag ctgtgaaggg aagggccttt catcctccag   1560
aggaaagagg gctggggtct cagaggccag agcataggga caggcaggag tcctgcagcc   1620
ctgatgcctg cccctcccag tacagaatct ctgtcctgac ccccacctgt tgaacctttc   1680
aaatcccagt gactcgccag ctttctctgt ggatattggc tgaattggtg gcttgtgtgg   1740
ctgcctggga gagcaattta cccctgarcc aaggaggggg tgggc                   1785

<210> 522
<211> 550
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (502)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (516)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (548)
<223> n equals a,t,g, or c

<400> 522
cccaaggtca cacagctggg atgtggcaga gctggggttc cagctcctgt tcccattgcw     60
ggacagctgc cacatctggc acccaattta ggaccccgcg ggaggcccaa gccccggggg    120
tggcggggga tcctagagga aagtggcaag gcaggaccct ggagcagagc cagtggaatg    180
tcaccatcgc ccaggtgggg atttttgtgt gttttgttca ctgctgtaca cccagccccc    240
agcacagcgc ctgtccagga caagtgccca gtaaacactt gggaagcaat gcaagcgtcc    300
tyccagcagc tcctgcaaac agacccccga cccaagccct tccttctgsc tccactgcca    360
ccactgctgc tcatctctgc tggcacagaa gtctcttccc tggtcttcca gaaatcccct    420
ctccacactc agccagaggg aagctattaa aactgcgggc cagcccacat tcagtccaca    480
gcaaagtcct ctctaaggga tntctgttgc ttggangaat aaaccctcgg attctttcct    540
tggctctngg                                                           550

<210> 523
<211> 639
<212> DNA
<213> Homo sapiens

<400> 523
aagcagcacg ccgccgcggc attttacgac gtcggcggtg acaggccctg ggactctggg     60
aatacccagc ttcctccccg caacccggtg aaagccaacg caatgttcgg tgcgggggac    120
gaggacgaca ccgatttcct ctcgccgagc ggcggtgcca gattggcctc actttttgga    180
ctggatsagg cagctgctgg ccatggaaat gaatttttcc agtacacagc cccaaaacag    240
cctaagaaag gccagggaac ggcagcaaca ggaaatcagg caacaccaaa aacagcacca    300
gccaccatga gcaytcccac aataytggtc gcaacagcag tccatgcata tcgatacaca    360
aatggkcaat atgtaaagca gggcaaattt ggtgctgcag ttctggggaa ccacacagcc    420
agagagktga kagtgctccc acatctcatg tatattcaga tgtcccaaat aataccaatg    480
agctggcttt tatctggctt gccygatgtc ttgtttatca gaagataagg atgattrttt    540
gtattgaatg ttaatttata acatcaagca tatagtaaat gatcacattt tgcttactat    600
tgtkcattaa aacaaatcca accattaaaa aaaaaaaaa                           639

<210> 524
<211> 743
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (728)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (736)
<223> n equals a,t,g, or c

<400> 524
gccggaggag cggcggcgtg gcgcacggcg acatggccgt tgtctcagag gacgactttc     60
agcacagttc aaactccacc tacrgaacca caagcagcag tctccgagct gaccaggagg    120
cactgcttga samgcygctg gaccgcccgc cccctggcct gcagaggccc gaggaccgct    180
tctgtggcac atacatcatc ttcttcagcc tgggcattgg cagtctactg ccatggaact    240
tctttatcac tgccaaggag tactggatgt tcaaactccg caactcctcc agcccagcca    300
ccggggagga ccctgagggc tcagacatcc tgaactactt tgagagctac cttgccgttg    360
cctccaccgt gccctccatg ctgtgcctgg tggccaactt cctgcttgtc aacagggttg    420
cagtccacat ccgtgtcctg gcctcactga cggtcatcct ggccatcttc atggtgataa    480
ctgcactggt gaaggtggac actttctcct ggacccgtgg cttttttgcg gtcaccattg    540
tctgcatggt gatcctcagc ggtgcctcca ctgtcttcag cagcagcatc tacggcatga    600
ccggctcctt tcctatgagg aactcccagg cactgatatc aggaggagcc atgggcggga    660
cggtcagcgc cgtggcctca ttggtggact tggctgcatc cagtgatgtg aggaacagcg    720
ccctggnnct tcttcntgac ggg                                            743

<210> 525
<211> 1169
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (535)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (646)
<223> n equals a,t,g, or c

<400> 525
tttttttttt tttttttttt tttttttttt tttttttttt tttttttttc accaaggagt     60
cataacctcc aagacatttt attttgacag aaaaggtgtg acacatccat cagaaatggg    120
atcagaaatt tttggtctcc cagtccccag tcctgatttt taattcccaa tttcaaaatt    180
ctatactaac atccaaacta taacttgact tttaaattta ccccactcct cgggaagaga    240
agtgcaatgc aggcaggcag ctgtttccag gagatcagaa aagggtaaat gaatactcaa    300
gatttacagc gtcaaaaggc tatgttgagg ataattctta tgactatgta aaagacaagg    360
tagtgaaatt gtgagggcmc tgggcccggc cactcacaga atgactgaag catgctgcag    420
tggagaactg gaaatgtatc tcttgttgcc ctccatctcc acccaccctc aagactggga    480
cttagaattc ccacgtccag cactgttgta gatggraggt aygttgtgct gaatnstgcg    540
ctggccacat caagacmcca catgtgttcc caagtggtat tgcagctgtc ctgaggccca    600
tctcttctcc ctctcatatt gggatctcat tgggagaaag tctagncaga ttcctgctmt    660
gctgggcctt ctcttacgcc agtgtggact tcacgggata gggcagacag agtattcgtt    720
gcatttattt gttctatcac tacagaagaa gcatttcaaa atgtgtacaa aaggatactc    780
tattcctcca gtggtacatc ccttgttcac agctaaacag caataattta acatcatcat    840
agaggcagac tggaaatatg actgcatttc tcatttacaa tcctgtgcat gtrctcgcca    900
gaagggcagc tgaagaccta aagctgtact ggatacaaca gattcgacct gaacaatcac    960
cacacacaac attataaaaa actgtattag aaagtattgg aaacaatatt gcatattaat   1020
atgtggttac acatgttcac agtgagtgcc atcgcaccaa aagcattatg tgcttctttt   1080
ttctgatgcc tgtacatctt aaataagtct aataattttg gttcatctta aagtaaaaat   1140
acattgaaat gaatgagaga gatctagat                                     1169

<210> 526
<211> 669
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (204)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (602)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (621)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (657)
<223> n equals a,t,g, or c

<400> 526
gcgcccagtt aatttttgta tttttagtag agatgggggt tttgccatgt tggtcaggct     60
gatctcgaac tcctgacctc aggtgatctg cccgccttgg cctcccaaag tgctgggatt    120
acaggcatga gccgccacgc tggcccggtc tggaaatctt atctaaaaag tagcaagtgc    180
tggaaaaagg gcctgggggg cggnggtggt tcttgtcgaa gcccccaggc tcctgtctca    240
gggatgaatg tggcgtctca ttgggattct tctcttgccc gaaagkgcyg ttttgaggac    300
tatcaatact ggggagtggg ggtgaagccg gacctcactc agggtgagat ttcagggccc    360
cggcatcctg aacacccccc acaccccaac attctcctcg ctctgtccct tcctcttctc    420
ccaacccctt ttgtgctggg gctgcgagct ccccgagttc tgcggtgact aaatcgaggc    480
cgagaaggga ggctgccccc caccaccctg tggtkcagta cccctccccc tggcttggag    540
aaagtggggt caccgcagct gagctggggg gttattttgg ctggagctgc tggagcaaaa    600
angctgggtc tgaaagccca ncaaggtctg gggattcgtt ggaaccgcgt ggtgttnggg    660
cggggctgt                                                            669

<210> 527
<211> 1480
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1479)
<223> n equals a,t,g, or c

<400> 527
caaaagctgg agctccccgc ggtggcggcc gctctagaac tagtggatcc cccgggctgc     60
aggaattcgg cacgagtatt gatacaatga tgattaacta tgaattctta agacttgcat    120
ttaaatgtga cattcttaaa aaaagaagag aaagaatttt aagagtagca gtatatatgt    180
ctgtgctccc taaaagttgt acttcattty ttttccatac actgtgtgct atttgtgtta    240
acatggaaga ggattcattg tttttatttt tattttttta attttttctt ttttattaag    300
ctagcatctg ccccagttgg tgttcaaata gcacttgact ctgcctgtga tatctgtatc    360
ttttctctaa tcagagatac agaggttgag tataaaataa acctgctcag ataggacaat    420
taagtgcact gtacaatttt cccagtttac aggtctatac ttaagggaaa agttgcaaga    480
atgctgaaaa aaaattgaac acaatctcat tgaggagcat tttttaaaaa ctaaaaaaaa    540
aaaaactttg ccagccattt acttgactat tgagcttact tacttggacg caacattgca    600
agcgctgtga atggaaacag aatacactta acatagaaat gaatgattst ttcrcttcta    660
cagtgcaagg atttttttgt acaaaacttt tttaaatata aatgttaaga aaaatttttt    720
ttaaaaaaca cttcattatg tttagggggg aactgcattt tagggttcca ttgtcttggt    780
ggtgttacaa gacttgttat ccatttaaaa atggtagtgg aaattctatg ccttggatac    840
acaccgctct tcaggttgta aaaaaaaaaa acatacattg gggaaaggtt taagattata    900
tagtacttaa atataggaaa atgcacactc atgttgattc ctatgctaaa atacatttat    960
ggtctttttt ctgtatttct agaatggtat ttgaattaaa tgttcatcta gtgttaggca   1020
ctatagtatt tatattgaag cttgtatttt taactgttgc ttgttctctt aaaaggtatc   1080
aatgtacctt ttttggtagt ggaaaaaaaa aagacaggct gccacagtat atttttttaa   1140
tttggcagga taatatagtg caaattattt gtatgcttca aaaaaaaaaa aaaagagaga   1200
aacaaaaaag tgtgacatta cagatgagaa gccatataat ggcggtttgg gggagcctgc   1260
tagaatgtca catggatggc tgtcataggg gttgtacata tccttttttg ktcctttttc   1320
ctgctgccat actgtatgca gtactgcaag ctaataacgt tggtttgkta tgtagtgtgc   1380
tttttgtccc tttccttcta tcaccctaca ttccagcatc ttaccttcat atgcagtaaa   1440
agaaagaaag aaaaaaaaag gaaaaaaaaa aaaacccant                         1480

<210> 528
<211> 2414
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2131)
<223> n equals a,t,g, or c

<400> 528
atgcgctgtg gctaatgccg tagtcggttc agggctgagc catcctgcgt gtcttgcgct     60
cggtggaaat gcccagccga gggacgcgac cagaggacag ctctgtgctg atccccaccg    120
acaattcgac cccacacaag gaggatctaa gcagcaagat taaagaacaa aaaattgtgg    180
tggatgaact ttctaacctt aagaagaata ggaccgaaca gaaatgctgt ctgagagcaa    240
gaatatattg gatgaactga aaaaagaata ccaagaaata gaaaacttag acaagaccaa    300
aatcaagaaa tagtcaacct gatttcacat aacaatgtgt ggcatttgtt gttctgtaaa    360
cttttctgct gagcatttca gtcaagattt aaaagaggac ttactatata atcttaaaca    420
gcggggaccc aatagtagta aacaattgtt aaagtctgat gttaactacc agtgtttatt    480
ttctgctcac gtcctacact tgaggggtgt tttgactacc cagcctgtgg aagatgaaag    540
aggcaatgtg tttctatgga atggagaaat ttttagtgga ataaaggttg aagctgaaga    600
gaatgacact caaattttgt ttaattatct ttcctcctgt aagaatgaat ctgagatttt    660
gtcactcttc tcagaagtac aaggtccctg gtcatttata tattatcaag catctagtca    720
ttatttatgg tttggtaggg atttttttgg tcgccgtagc ttgctttggc attttagtaa    780
tttgggcaag agtttctgcc tctcttcagt tggcacccaa acatctggat tggcaaatca    840
gtggcaagaa gttccagcat ctggactttt cagaattgat cttaagtcta ctgtcatttc    900
cagatgcatt attttacaac tgtatccttg gaaatatatt tctagggaga atattattga    960
agaaaatgtt aatagcctga gtcaaatttc agcagactta ccagcatttg tatcagtggt   1020
agcaaatgaa gccaaactgt atcttgaaaa acctgttgtt cctttaaata tgatgttgcc   1080
acaagctgca ttggagactc attgcagtaa tatttccaat gtgccaccta caagagagat   1140
acttcaagtc tttcttactg atgtacacat gaaggaagta attcagcagt tcattgatgt   1200
cctgagtgta gcagtcaaga aacgtgtctt gtgtttacct agggatgaaa acctgacagc   1260
aaatgaagtt ttgaaaacgt gtgataggaa agcaaatgtt gcaatcctgt tttctggggg   1320
cattgattcc atggttattg caacccttgc tgaccgtcat attcctttag atgaaccaat   1380
tgatcttctt aatgtagctt tcatagctga agaaaagacc atgccaacta cctttaacag   1440
agaagggaat aaacagaaaa ataaatgtga aataccttca gaagaattct ctaaagatgt   1500
tgctgctgct gctgctgaca gtcctaataa acatgtcagt gtaccagatc gaatcacagg   1560
aagggcggga ctaaaggaac tacaagctgt tagcccttcc cgaatttgga attttgttga   1620
aattaatgtt tctatggaag aactgcagaa attaagaaga actcgaatat gtcacttaat   1680
tcggccattg gatacagttt tggatgatag cattggctgt gcagtctggt ttgcttctag   1740
aggaattggt tggttagtgg cccaggaagg agtgaaatcc tatcagagca atgcaaaggt   1800
agttctcact ggaattggtg cagatgagca acttgcaggt tattctcgtc atcgtgtccg   1860
ctttcagtcg catgggctgg aaggattgaa taaggaaata atgatggaac tgggtcgaat   1920
ttcttctaga aatcttggtc gtgatgacag agttattggt gatcatggaa aagaagcaag   1980
atttcctttc ctggatgaaa atgttgtctc ctttctaaat tctctgccga tttgggaaaa   2040
agcaaacttg actttacccc gaggaattgg tgaaaaatta cttttacgcc ttgcagctgt   2100
ggaacttggt cttacagcct ctgctcttct ncccaaacgg gccatgcagt ttggatcaag   2160
aattgcaaaa atggaaaaaa ttaatgaaaa ggcatctgat aaatgtggac ggctccaaat   2220
catgtcctta gaaaatcttt ctattgaaaa ggagactaaa ttgtaatgtg attcacaatg   2280
taacaatata aaaataagtt tttatataat tatataaaag taagatactc tgctgcttta   2340
ctattgtata atatagtagt tttaaagttc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2400
aaaaaggggg gggg                                                     2414

<210> 529
<211> 1055
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (502)
<223> n equals a,t,g, or c

<400> 529
ccaactataa tcattcggca gacagctggg cagctctcct tctccatcaa ggtagcagag     60
gatgtggcca tggccttctc agctgaacag gacctgcagc tctgtgttgg ggggtgccct    120
ccaagtcagc gactctctcg atcagagcgc aatcgtcggg gagctataac cattgatact    180
gccagacggc tgtgcaagga agggcttcca gtggaagatg cttacttcca ttcctgtgtc    240
tttgatgttt taatttctgg tgatcccaac tttaccgtgg cagctcaggc agcactggag    300
gatgcccgag ccttcctgcc agacttagag aagctgcatc tcttcccctc agatgctggg    360
gttcctcttt cctcagcaac cctcttagct ccactccttt ctgggctctt tgttctgtgg    420
ctttgcattc agtaagggga ccatcagtcc cattactagt ttggaaatga tttggagata    480
cagattggca tagaagaatg tnaaagaatc attaaaggaa gcagggccta ggagacacgt    540
gaaacaatga cattatccag agtcagatga ggctgcagtc cagggttgaa attatcacag    600
aataaggatt ctgggcaagg ttactgcatt ccggatctct gtggggctct tcaccaattt    660
ttccagcctc atttatagta aacaaattgt tctaatccat ttactgcaga tttcaccctt    720
ataagtttag aggtcatgaa ggttttaatg atcagtaaag atttaagggt tgagattttt    780
aagaggcaag agctgaaagc agaagacatg atcattagcc ataagaaact caaaggagga    840
agacataatt agggaaagaa gtctatttga tgaatatgtg tgtgtaaggt atgttctgct    900
ttcttgattc aaaaatgaag caggcattgt ctagctctta ggtgaaggga gtctctgctt    960
ttgaagaatg gcacaggtag gacagaagta tcatccctac cccctaacta atctgttatt   1020
aaagctacaa attcttcaca ccaaaaaaaa aaaaa                              1055

<210> 530
<211> 1096
<212> DNA
<213> Homo sapiens

<400> 530
ggcagagcaa gatgggggct taccacacca tcgagctgga gcccaaccgc cagttcaccc     60
tggccaagaa gcagtgggat agtgtggtac tggagcgcat cgagcaggcc tgtracccag    120
cctggagcgc tgatgtggcg gctgtggtca tgcaggaagg cctcgcccat atctgcttag    180
tcactcccag catgaccctc actcgggcca aggtggaggt gaacatccct aggaaaagga    240
aaggcaattg ctctcagcat gaccgggcct tggagcggtt ctatgaacag gtggtccagg    300
ctatccagcg ccacatacac tttgatgttg taaagtgcat cctggtggcc agcccaggat    360
ttgtgaggga gcagttctgc gactacatgt ttcaacaagc agtgaagacc gacaacaaac    420
tgctcctgga aaaccggtcc aaatttcttc aggtacatgc ctcctccgga cacaagtact    480
ccctgaaaga ggccctttgt gaccctactg tggctagccg cctttcagac actaaagctg    540
ctggggaagt caaagccttg gatgacttct ataaaatgtt acagcatgaa ccggatcgag    600
ctttctatgg actcaagcag gtggagaagg ccaatgaagc catggcaatt gacacattgc    660
tcatcagcga tgagctcttc aggcatcagg atgtagccac acggagccgg tatgtgaggc    720
tggtggacag tgtgaaagag aatgcaggca ccgttaggat attctctagt cttcacgttt    780
ctggggaaca gctcagccag ttgactgggg tagctgccat tctccgcttc cctgttcccg    840
aactttctga ccaagagggt gattccagtt ctgaagagga ttaatgattg aaacttaaaa    900
ttgagacaat cttgtgtttc ctaaactgtt acagtacatt tctcagcatc cttgtgacag    960
aaagctgcaa gaakggcact ttttgattca tacagggatt tcttatgtct ttggctacac   1020
tagatatttt gtgattggca agacatgtat ttaaacaata aactaaaagg aaataatcwm   1080
mamrtaaaaa aaatgc                                                   1096

<210> 531
<211> 690
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (333)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (683)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (689)
<223> n equals a,t,g, or c

<400> 531
tttaaggagt aacaatgcat cgaacgtggg tttttgcatg tttgcttgtc tcatggagac     60
agcttgttac caactatatt tggtaacaag cactactgtt gactcatgat ttccttaatg    120
ccttagtatc tatcatgtat atgtttactt tgacatcagg gcatggaaag ttctattcaa    180
caattcctgg gtctaatttc agtagttcca ttctctgtga cctcacaatg ggagccagca    240
gccttccatc ttgtgatggt gacttgctct tctaggtgga gtgggaggag caccgactat    300
gtgctgggac agggcttggy ttcaagggtc tgnttcagcc ccttgctggc tgcatgacty    360
tggsaaatca mttactgaca tttgttgtaa tgcacatact ggcattcatt gtagaatttc    420
tattctggtg gtgatagtca attggttctt tatgcaaacg gaggtgatat caacactgaa    480
aattctgagt gaattgttaa actctggtga attgctctgt gagtggttag gcaaaattga    540
agaggactgc tctgctggac aggcccaatt tattaggccc cgctctaaat atgactttta    600
tccccatact ttttaaataa ttagcttttg aactatttta catctgaaaa taaaagacag    660
aatatggaaa atatctggct ttnccagana                                     690

<210> 532
<211> 793
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (787)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (792)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (793)
<223> n equals a,t,g, or c

<400> 532
gggacccacg gcaggcgcga atcccagcgg ccggcgggcg gcggggatac ttctacatag     60
acataatcaa gttttgacta tttggaaacc aagcatcatt aaaattctct caaactgcta    120
attgcgaaga atcgataaca tttcaagaag tgataacatt tctctgaaca agaaaagaag    180
tgattgacca cgttttaaaa gtactctggc actggtgctg tgttttcttc ccctccctaa    240
atttgaagaa ctatggagaa atggtgctgg taaaccgcct atgtttggtg attatgaagc    300
tcagagacac tggcaagaaa taacttttaa tttaccggtc aaacaatggt attttaacag    360
cagtgataac aatttacagt attggggatt ggattaccca cctcttacag cttatcatag    420
tctcctatgt gcatatgtgg cmaagtttat aaatccagac tggattgctc tccatacatc    480
acgtggatat gagagtcagg cacataagct cttcatgcgt acaacagttt taattgctga    540
tctgctgatt tacatacctg cagtggtttt gtactgttgt tgcttaaaag aaatctcaac    600
taagaaaaag attgctaatg cattatgcat cttgctgtat ccaggcctta ttcttataga    660
ctatgggaca ttttcaatat aattctgtga gtcttggctt tgctttgtgg ggtgtcctgg    720
gaatatcttg tgactgcgac ctcctaaggt caactggcat tttgcttagc tataaatata    780
accagangga cnn                                                       793

<210> 533
<211> 804
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (794)
<223> n equals a,t,g, or c

<400> 533
ggcacaggtc tgcccagaca agctgaagga ccacaggaaa agccatggag acttcagcat     60
cctcctccca gcctcaggac aacagtcaag tccacagaga aacagaagat gtagactatg    120
gagagacaga tttccacaag caagatggga aggctggact cttttcccaa gaacaatatg    180
agagaaacaa gtcttcttcc tcctcctcct cttcctcctc atcctcctca tcttcttcat    240
cctcctcctc ctcaggtcct gggcatgggg agcctgacgt tttgaaggat gagcttcaac    300
tctatggaga tgctcctgga gaggtggtac cctctgggga atcaggactc cgaaggagag    360
gctctgaccc agcaagtgga gaagtggagg cctctcagtt aagaagactg aatataaaga    420
aagatgatga gtttttccat ttcgtcctcc tgtgctttgc catcggggcc ttgctggtgt    480
gttatcacta ttacgcagac tggttcatgt ctcttggggt cggcctgctc accttcgcct    540
ccctggaaac cgttggcatc tacttcggac tagtgtaccg tatccacagc gtcctccaag    600
gcttcatccc cctcttccag aagtttaggc tgacagggtt caggaagact gactgaggcc    660
acttccaggt gggcagcaga ggcaggcccc agtgtgacca ccactgcgac ccctgagccc    720
acaagggcag agcagcattc tgagagacgc acaggagacc aagccagacc aataaacaga    780
acacttttcc ttcnaaaaaa aaat                                           804

<210> 534
<211> 988
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (929)
<223> n equals a,t,g, or c

<400> 534
agcagcactc ccacasctcc cttccagcag gccagtggtt atggccagca cggctacagt     60
acaggttatg acgacctgac ccaggggaca gcagcaggag actactccaa aggtggctat    120
gctggatcat cgcaggcacc aaacaagtct gcaggttctg ggcctggcaa aggagtatca    180
gtgtcttcaa gcaccactgg tctacctgat atgactggtt ctgtctacaa taagacacag    240
acttttgaca agcagggatt tcatgcaggg acgcctccac ctttcagcct gccctcggtc    300
ttgggctcca ctgggcccct ggctcgggag cggcccctgg ctatgcaccc ccaccattcc    360
tacacatctt gccagcccac cagcagcccc actcacagct gctgcaccac caccttccgc    420
agatgcacag agtggctcgg gtcagcgcag cagcccagct ccctgcagcc caagtctcaa    480
gcctccaaac ctgcctacgg caactctcca tactggacaa actaaaccca gaagagaggg    540
gtgggctggg gcaaggctta tcctgggcag gagagaacac acgagcacgt atttgggagc    600
ccagtgccct ttcctagaat tcccgacatg tgtcagccat gcctctgtgg ggagtctgcc    660
tcccagactg gctactgtat gtaatgtatt tatgtatgta tttgtaaatg tgatagaagt    720
ctggggggga gttgggggat ggcggcagat gttagccagg tctgccctcc ccattcaagc    780
cccttctcca ctgtagcaaa ataagcaccc ccaccccatc tgccttcagg tcttcttcac    840
agcctgcact gcccagtggg ccactagggg cagtctctgg aagggctggt tcaaggctgt    900
ttgggtatag gggtcargta ccatgaagna tcacgyttgt ytcamtcctt tggraattgt    960
tttctttccc gtggtaatta cttcatac                                       988

<210> 535
<211> 832
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (789)
<223> n equals a,t,g, or c

<400> 535
gctttgggag tgatttcaaa ctttcagtct agcccaaaat atggtagtga agaagattgt     60
tctagtgcca cttcaggctc agtgggagcc aacagcacca cagggggcat cgctgtagga    120
gcatccagct ccaaaacaaa caccctggac atgcagagct caggatttga tgcactacta    180
catgagatcc aggagatccg ggaaacccag gccagactag aggaatcctt tgagactctc    240
aaggaacatt atcagaggga ctattcctta ataatgcaga ccttacagga ggagcgatat    300
agatgtgaac gattggaaga acagctaaat gacctaacag agctccacca gaatgaaatc    360
ttgaacttga agcaggaact ggcaagcatg gaagaaaaaa tcgcgtatca gtcctatgaa    420
cgggcccggg acatycagga ggccctggag gcatgccaga cgcgcatctc caagatggag    480
ctgcagcagc agcagcagca ggtggtgcag ctagaarggc tggagaatgc cactgcccgg    540
aaccttctgg gcaaactcat caacatcctc ctggctgtca tggcagtcct tttggtcttt    600
gtctccactg tagccaactg tgtggtcccc ctcatgaaga ctcgcaacag gacgttcagc    660
actttattcc ttgtggtttt tattgccttt ctctggaagc actgggacgc cctcttcagc    720
tatgtgggaa cggttctttt catcccctta gatgatgctg gcacagaagg cattgttccc    780
taccctctng gcgagtgcat gcagcagaga gttagacagc aacttaccta ct            832

<210> 536
<211> 1165
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (903)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1163)
<223> n equals a,t,g, or c

<400> 536
aattcggcag agcgtctcta tggtggcggc ggatttggag ggaccctacg aaccaggagt     60
caggcgagcc gatctggggc tgcaggatgt tccgctggga gcgctccatt cccctgcgag    120
gctcggccgc cgccctgtgc aacaacctca gtgtgctgca gctgccggct cgcaacctca    180
cgtattttgg cgtggttcat ggaccaagcg cccagcttct cagcgctgct cctgagggtg    240
tgcccttggc ccagcgccag ytccacgcta aggagggtgc tggagtgagt cccccactta    300
tcactcaggt ccactggtgt gtcctcccct tccgagtgct gctggtactc acctcacatc    360
gaggaataca gatgtacgag tccaatggct acaccatggt ctactggcat gcactggact    420
ctggagatgc ctccccagta caggctgtgt ttgcccgggg aattgctgcc agtggccact    480
tcatctgtgt gggaacgtgg tcaggccggg tgctggtgtt tgacatccca gcaaagggtc    540
ccaacattgt actgagcgag gagctggctg ggcaccagat gccaatcaca gacattgcca    600
ccgagcctgc ccagggacag gattgtgtgg ctgacatggt gacggcagat gactcaggct    660
tgctgtgtgt ctggcggtca gggccagaat tcacattatt gacccgcatt ccaggatttg    720
gagttccgtg cccctctgtg cagctgtggc aggggatcat agcagcaggc tatgggaacg    780
gacaagtgca tctatatgag gccactacag gaaatctaca tgtccagatc aatgcccatg    840
cccgggcgca tctgcgccct ggacctggct tctgaggtgg gcaagctact ctctgcaggt    900
ganggacacc tttgtgcata tctggaagct gagcagaaac ccagagagtg gctacattga    960
ggtggaacat gtcatggtga gtgtgtcgcc gacacccagc tgtgtggtgc tcgattttgt   1020
gattcctcag gcaactcctt tgctgtgact ggctatgacc ttgcggagat ccggagattc   1080
agcagtgtgt gagaagagca gccttccttt gtccctgtgg tattcataaa gtacccgctc   1140
cacccaggaa aaaaaaaaaa aanaa                                         1165

<210> 537
<211> 956
<212> DNA
<213> Homo sapiens

<400> 537
ggaaggcaag atggcggcgc ccatggaggt ggccgtgtgt acggactcgg cggccccgat     60
gtggagctgc atcgtgtggg aacttcactc gggcgccaac ctgctcacct accgcggcgg    120
ccaggcggga ccccgcggcc tggcgctgct caatggcgag tatctgctgg cggcgcagct    180
gggcaagaay tacatcagcg cctgggagct scagcggaag gaccagctcc agcagaagat    240
catgtgcccc gggcctgtca cctgtctgac tgcatcaccc aatggtctct acgtcctggc    300
aggagttgca gaaagcatcc acctgtggga ggtctccacc gggaaccttc tggtcatcct    360
gagtcgacac taccaggacg tctcctgcct tcagttcaca ggggacagca gccacttcat    420
ctcagggggc aaggactgcc tggtgctggt ttggagcctc tgcagcgtgc tgmaggccga    480
cccctccagg attccggcgc ccaggcacgt ctggtctcac cacacgctcc ccatcacgga    540
cctgcactgc ggctttgggg gccccctggc ccgggtggcc acctcctcac tggaccagac    600
ggtgaagcta tgggaggtct cctcggggga gctgctgctc tccgtcctct ttgacgtgtc    660
catcatggca gtgaccatgg acctggctga gcaccatatg ttctgcgggg gcagtgaggg    720
ctccatcttc caggtcgacc tcttcacctg gcccggacag agggagagga gcttccaccc    780
agagcaggac gccgggaagg tcttcaaagg gcacaggaac caggtgactt gcctgtcagt    840
gtccactgac ggcagcgtgc tgctctcagg ctcccacgac gagaccgtgc gcctctggga    900
cgtgcagagc aagcagtgca tccggacggt ggcctcaaag gccmagtcac caatgc        956

<210> 538
<211> 1195
<212> DNA
<213> Homo sapiens

<400> 538
ggccggctcc taccctgaag gtgcacctgc artcctcgcc gataagaggc agcagttcgg     60
aagccggttc ctgagmgatc cggcgcgcgt cttccaccac aatgcctggg acaatgtgga    120
gtggtcggaa gagcaagccg cggcggcgga gagaaaagtc caggagaaca gtatccagcg    180
ggtgtgccag gagaaacaag ttgattatga gatcaatgcc cacaaatact ggaatgactt    240
ctacaaaatc cacgaaaatg ggtttttcaa ggatagacat tggcttttta ccgaattccc    300
tgagctggca cctagccaaa atcaaaatca tttgaaggay tggttcttgg agaacaagag    360
tgaagtayst gaatgtagaa acaatgagga tggacctggt ttaataatgg aagaacagca    420
caagtgttct tcgaagagcc ttgaacataa aacacagaca cctcctgtgg aggagaatgt    480
aactcagaaa attagtgacc tggaaatttg tgctgatgag tttcctggat cctcagccac    540
ctaccgaata ctggaggttg gctgtggtgt gggaaacaca gtctttccaa ttttacaaac    600
gaacaatgac ccaggactct ttgtttattg ctgtgatttt tcttccacag ctatagaact    660
ggtccagaca aattcagaat atgatccttc tcggtgtttt gcctttgttc acgacctgtg    720
tgatgaagag aagagttacc cagtgcccaa gggcagtctt gatattatca ttctcatatt    780
tgttctttca gcaattgttc cagacaagat gcagaaggct atcaacaggc tgagcaggct    840
tctgaaacct ggsgggatgr trcttctgcg agattacggc cgctatgaca tggctcagct    900
tcggtttaaa aaaggtcagt gtctatctgg aaatttctay gtgagaggtg atggaaccag    960
agtttacttc ttcacacaag aggaactgga cacgcttttc accactgctg gactggaaaa   1020
agttcagaac ctggtggatc gccgactgca ggtgaaccga ggaaagcaac tgacaatgta   1080
ccgggtttgg attcagtgca aatactgcaa gccccttctg tccagcacca gctragaggc   1140
acctgctgcc aacacgatgc aagcccrttg tgtttccgag ctttttttaa aaaaa        1195

<210> 539
<211> 404
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<400> 539
aatatgccan gttcactcaa gagcaagtag acaaaatctn ccgcgccgcc gctctggctg     60
ctgcagatgc tcgaatccca ctcgcgaaaa tggccgttgc cgaatccggc atgggtatcg    120
tcgaagataa agtgatcaaa aaccactttg cttctgaata tatctacaac gcctataaag    180
atgaaaaaac ctgtggtgtt ctgtctgaag acgacacttt tggtaccaty actatcgctg    240
aaccaatcgg tattatttgc ggtatcgttc cgaccactaa cccgacttca actgctatct    300
tcaaatcgct gatcagtctg aagacccgta acgccattat cttctccccg cacccgcgtg    360
caaaagatgc caccaacaaa gcggctgata tcgttctgca ggct                     404

<210> 540
<211> 1893
<212> DNA
<213> Homo sapiens

<400> 540
tacatttttg tgcaagagac ccccagagga agattagtca taattcgagt ccaaggaaga     60
cggctaattc tagcgatcaa tgtttgtttc ccattswgaa gaagtagatg gctgccctgt    120
cattctagtt tgtggatccc aggatgttgg aaagtcaaca tttaatagat acctgattaa    180
ccatttgtta aatagtcttc cctgcgttga ctatttggaa tgtgatctgg gacagacaga    240
atttacccct cctggttgca tttctttgct taatattaca gaaccagttc tgggaccacc    300
tttcactcac ctgaggactc cacagaagat ggtatattat gggaaacctt cttgtaaaaa    360
caactatgag aattatattg acatagtgaa atatgtgttc agcgcttaca agagagagtc    420
ccctctcatc gtcaacacta tgggatgggt ttcagaccag gggctcctgc ttctcattga    480
tctgatccga ttgctgtctc ccagccacgt ggttcagttc cgctctgacc acagtaaata    540
tatgccagac cttaccccgc agtatgtaga tgacatggat ggcttgtaca caaaaagcaa    600
gaccaagatg agaaatcgac gtttcagact cgcagcattt gcagatgctt tggaatttgc    660
tgatgaagaa aaagagagtc cagttgagtt cactggacat aaactgatag gtgtttatac    720
agactttgca ttcagaataa ctccaagaaa tagagagtca cataacaaaa ttcttcgaga    780
tctgtccatc ttgagttacc ttagccagct gcagcccccg atgcccaaac cactttctcc    840
tttacatagc ctgacaccct atcaggtccc tttcaatgca gtcgcactcc ggattaccca    900
ctctgatgtc gcccctaccc atatactata tgctgtaaac gccagctggg ttggtctttg    960
caagatccag gatgacgtca gaggatacac gaatgggccc atcctgcttg cccagactcc   1020
aatctgtgac tgcttgggct ttggcatctg tagaggcatt gacatggaga agcggctgta   1080
ccacatcctc acccctgtsc ccccggaaga gctaaggacc gtgaattgtc tgytcgttgg   1140
agctattgcc attccacatt gtgtccttaa gtgccagcgt gggatcgaag ggacagtacc   1200
ttatgtcaca acggattaca attttaaact tcctggagca tcagagaaaa ttggagcaag   1260
agaacctgag gaggcacata aagagaaacc ataccgaaga cctaagttct gtcgaaaaat   1320
gaagtgatgc tcgcgttttt aataagggaa gaaactttcc taccagaaag ctttgtctca   1380
agcctgacca caagagacat gatggagttt catggccatg aatggtgccc ttattarcaa   1440
cagtgttttt tgtgtaattc gtgaatgtca tatagtagtc ttaagtttct cttttaaagc   1500
tgcatgagct agaatttgtt ctagtcttct gtgtgatact catacttgct gtccagaggg   1560
agtaaaacag cagagaacag tttgtgtkcc attaaaacag agattcctca gaaagttctt   1620
cagggacctg gttattagaa tcaggataaa aataaggaaa ctggggccat tacaatgtac   1680
cgagaaggaa ggaagaaggc caacctgcag gatctcaagc ataatggata caagggctcs   1740
cacgggcctt gcctgagcca tgtgcagagc tggggtccag cggtctgctt ccttggagcc   1800
agtgtggatg gttacagccc atccatttgg tgcagttgta cttggtctgt tatattcaat   1860
caaggtttaa ttagataggg ctggggcatg gtt                                1893

<210> 541
<211> 1943
<212> DNA
<213> Homo sapiens

<400> 541
cgcaccctgc cttccggggg ccggacaggg cccgggctgc tgtctcaaga cagccagaca     60
aggagttctc cttcatggat gaggaggagg aggatgaaat ccgtgtgtga ggcggacagt    120
gggtggccac cgggagctct tggctgcatc ttctccctgc ccccacccca ctatgacctt    180
tgaccctacg gcgcaggggc agccaggacc cttgattcag accatggacc ctggaccttg    240
tagatgaggg acactggcct ggccctcggg tcttcggagg acgtaggggg ctggcatggg    300
tgccgactgg ctgcctgact tcatcatgct ccctgcactt aggctgcgtg ggacaagggc    360
tgtgttgtca cagcaggaat aggttttcct ctgttggcct ccctttcctc caccctggcc    420
tcaaatggat gccagatgcc aaccccagtt ctggccacgt acagccagcg ggtcagccca    480
gaggcagcct cagctccagg gctaaggact ctcggctccc attttctytg ctggcgtttc    540
tgctgtgccc agcagtggct gctgggsaag cagctgcagc aggagggaga cggtcttgcc    600
tctcagcccc tccctgcccc accccagctc ctgccctgga aatctggagc cccttggagc    660
tgagctggac ggggggccag ctgcgagcat gtgcactaaa cgcagccctt tccaggggaa    720
gagaacagga tggagaatgg aaggaaagcc ccccaggctt cgtgaattgc aagaagggac    780
ccttccagga tgacactagg aacagggcta gggcactcgc tcagtcccta ggggcttgtt    840
tgttctttat tattgtgttt aaatccttat agagcaatat caggatggtg ttaataggtc    900
tgcctcagaa tgagaatcaa tccttttaga aaacctttat actaagcctc ctcttcraaa    960
ttcacagtgg cgattagcgg actggagtct ggtggcgatt agcggactgg agtctgggga   1020
catccgtggc aaagacacca gctcaacttt agtgcttccc aactttattt agaatgacat   1080
ggggtgggtg tctggtgtgt gtgttttccc tacgcacctc ccatagctat taacaactga   1140
ggaaggccag tgcagaatat ttttggagaa cgattttttt tttaaataat atatcattcc   1200
tatgggggga aagccttttt tttctttttg gctgagttat tccctccctc ccctcaatac   1260
cctcagtact gactacttcc ctttcttttc tcaggcctcc ccccaccgac ttttgaggcc   1320
agggttggcc agatttagca aaaccaaaac agagtgctga gttaaacgca aatttcaggt   1380
aaacaaaaga taattttcta gcattaatat gccccacgca atatttggaa cacttatgtg   1440
aaaaatgatt tgtttttctg aaattyacgt ttctctctga gtcctgtaac tgtccccgag   1500
gggattgagc agaagctcgg gtatgagccc tgaggttgac tgccggttat ttttctgtcc   1560
tgggaacagc ctgacccacc tccctgtctc catgtagcca gtgrggggag ggggagacac   1620
agaaccaacc acagccaggg gcgtccccat ggcgactgtg gcccggcccc tcctctcttg   1680
cctgactctc ctctcttgcc tgactctaga cactaactta gttccaggtt cggtgccctg   1740
ttggtgctcc tgtttccaat agcttaggtc ccatggtggg ggaggaacct cagggctatg   1800
cagcccccgc cagctgccct craatcccgt ccaggccart tccagattct aaactgattt   1860
ttttcatgat attgtcaaaa cagtgaggaa acattaaaaa aaaagcccta aagcaaaaaa   1920
aaaaaaaaaa aaaaaaaaaa aaa                                           1943

<210> 542
<211> 804
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (792)
<223> n equals a,t,g, or c

<400> 542
gtccgacgtc gccggactgg gcgcgcctgg tgagccagga ggggagagac aaggagggac     60
ggaggaggag gaggtatctc tgcattagcc agattggaca tatgtaaagg gacatcagta    120
tatctggatc atcagattgt gcttcaagaa gaccataggg aagaacgcat tttcatcttg    180
ctgcaaaagt tgcaatagaa gatctgaagg tttgaatggg ccaatgagta tcctcatcat    240
tgaagcattc tatggaggct cccataaaca gctggtggat cttcttcaag aagagttagg    300
agactgtgtc gtttataccc ttcctgcaaa gaaatggcat tggagagccc ggacatctgc    360
tttatatttc tctcagacca ttcccatcag tgagcattac aggaccctct ttgcaagttc    420
agtgcttaac ctgaccgaac tggctgccct tcggcctgac cttgggaaac tgaaaaagat    480
tctgtatttt cacgagaacc agttgatata tcctgtcaag aaatgtcagg agagggattt    540
ccaatatgga tacaaccaaa ttctttcatg cctggtggct gatgtggttg tattcaactc    600
agtttttaat atggaatcat ttctcacttc catgggaaaa tttatgaagc tgattcctga    660
tcacagaccc aaggatctgg aaagcatcat cagacccaag tgccaagtta tttactttcc    720
catcaggttt cctgatgtga gcagattcat gcccaagcac aaaacaaccc wtttaagaag    780
atgctcggcc tnaaaggaaa tggc                                           804

<210> 543
<211> 492
<212> DNA
<213> Homo sapiens

<400> 543
ggcggtccgg gagcacagag agccgtgggg gaaaagaccc cctctccagc cctgggggcc     60
tggatctcgg aggagcaatt acaatttgga aggcatctca gtgaagatgt tccttcgagg    120
gcgccccatt accatgtaca tcccgtctgg catccgcagc cttgaggagc tgccgagtgg    180
cccaccgcca gagaccctca gccttgactg ggtttatggg tacaggggtc gtgactcccg    240
ctctaatctg tttgtgttgc gctctgggga ggtggtctac tttatcgcct gtgtggtggt    300
gctgtaccgg cctggaggag gcccaggggg tcctggaggt ggcggccaga gacattaccg    360
ggggcacaca gactgcgttc gatgccttgc tgttcaccct gatggtgttc gggtagcctc    420
gggacagaca gctggagtgg ataaggatgg aaagcccctg cagcctgtgg ttcacatctg    480
ggactcaaag ac                                                        492

<210> 544
<211> 593
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (284)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (300)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (490)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (530)
<223> n equals a,t,g, or c

<400> 544
tttcctatca aagcacctta gacatgcacg aggaagaaat atacacctct cttcagtggg     60
atagcccagc accagacact taccagaaat gtctgtcttc caacaaatgt tcaggagcat    120
gctgtcttgt gatggtgatt tcatgtgttt tctgcatggg attattaacr gsatccattt    180
tcttgggcgt caagttgttg caggtgtcca ccattgcgat gcagcagcaa gaaaaactca    240
tccaacaaga gagggcactg ctaaacttta cagaatggga aganaagctg tgcccttcan    300
atgaaatatt gccaagcctt catgcaaaac tcattaagtt cagcccataa cagcagtcct    360
tgtccaaaca attggattca gaacagagaa agttgttact atgtcyctga aatttggagc    420
atttggcaca ccagtcaaga gaattgttta aaggaaggtt ccacgctgct acaaatagag    480
agcaaagaan aaatggtaaa cactgttttg tggtctcatg ttattctgan aatatcattt    540
tacttattaa aagaaatccc tcattctcat aagaaaaaat tccttaatat tct           593

<210> 545
<211> 450
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (368)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (413)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (446)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (450)
<223> n equals a,t,g, or c

<400> 545
gacaagacgc cagccggact gaggtggttt ctaagcagtg gcttcacagc tgtttcccac     60
ttgtcatctt tatgagcaga aaacctgaac tgtgtttaca acctagcttt gcacattgtc    120
agatttttcc cagcatcctc cagaagtgca aaagcccagc ttcctcgcct caggctgtcc    180
cgggtgtctg gagagcgttc actctcccag gccaagcctg ccttgggacg gggctctggc    240
caggcctgcc tgccctgctg cagtggccca gcccatctcc tccgatggaa gagtggcccc    300
ggacgcacat cctccctatg ttggtgggag cagtggcagg agcagtggca gcgagcagga    360
caggcggnta tctcttcacc caaaggacct tggtaccagg attgcacgta ctnctggctt    420
tgtgatgggc atttttgctc catggngggn                                     450

<210> 546
<211> 1991
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1991)
<223> n equals a,t,g, or c

<400> 546
gcggaggaga gaaatgcccc aggctctccg gggcacacaa agcgcaggcg cagcgggttg     60
ggtggcagca gcatcgagta gcggccgctt aggcagcaac atccgcaaca agtgtagaca    120
aggtcccgcc tgactccgct ctggaaagtc cttttgaaga aatggccctg gtgaggggcg    180
gctggctgtg gagacagagc tccatcctcc gccgctggaa gcggaactgg tttgccctgt    240
ggctggacgg gaccctggga tactaccacg atgagacagc gcaggacgag gaggaccgtg    300
tgctcatcca cttcaatgtc cgtgacataa agatcggccc agagtgccat gatgtgcagc    360
ccccagaggg ccggagccga gatggcctgc tgactgtgaa cctacgggaa ggcggccgcc    420
tgcacctctg tgcggagacc aaggatgatg ccctagcatg gaagacagca ctgctggagg    480
caaactccac cccggtgcgc gtctacagcc cgtaccaaga ctactacgag gtggtgcccc    540
ccaatgcaca cgaggccacg tatgtccgca gctactacgg accgccctac gcaggccctg    600
gcgtgacgca cgtgatagtg cgggaggatc cctgctacag cgccggcgcc cctctggcca    660
tgggcatgct tgcgggascg ccactgggcg gcrywgggct cgctcatgtg gtcgccctgc    720
tggttctgag ccctgggact cggagcactg acccctgcgc ttggattgct agactcctct    780
tcctcctgga ccccatcctc taccatccaa gccctgtccc actttggccc tatcctctcc    840
attagctcct tccgggtttg gaccattccc cccactccct acccttaatc cccacatggg    900
aagaagctat catcacaggt acaaacatcg cttgaagtct tcacatctac cactagacac    960
ccccaaaatc tgttatagac atttatggat acatttcctc taaacacaac agggcacagc   1020
aaatacgact tcatttggct tcgagttccc caggcgctgt agacacaaca tgaatcgggc   1080
tctctgctct ctccttaggg agctcgagtc ctggtgggga gaacaggagt aaacaaggac   1140
ttgacaaagc tgaagagtta tcagtccttt gacaaggaca ggtggggcag ggagcaagac   1200
aggtaggctg gaagaacagt tattggcaag tatgcagagc cgtgaacgtc atggcatgtc   1260
caaggaatta aatgggagtt catttgggct ggggtggagg ctgggatcag accgtggtgg   1320
gccttcaagc taaggagctt cctaggtgaa aggggagatg tgagccttct ctggagggaa   1380
gtttcatgat tgcatctata atgaatatat tgcctgtttt gtgaatactg acacatgtcc   1440
atacctaaaa cactcctgag ttaagtccca tccttcccac aaacagcttc ctggctggta   1500
cccatgataa caattgagct gaacctgggg acccctggtt ggggaacagg tgagttctat   1560
ttgagacttc cagccctaga aagctgcctc cgtccagaaa tgcctctcac accaggagct   1620
cggccctctc tttgtagctg tgactgtcac cctctcaggc tttgtctcat ccttcattct   1680
gaataagatg gcagtgttct cctctggggc ctgatccacc tctacaccag cccaggaagc   1740
cccatctgtg cctgccctca ggtggtccac cagtctcccc ctttggttcc cttccagtct   1800
cttccccctt tctatcccaa tcaccaatag aaatgctaac atccctgcct ggtagccaga   1860
ctagcccact aaagctcccc tgtaaatggg ggctccatta gttctgctgc cgagactaat   1920
aaagatttgg ttggctctar maaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1980
aaaaaaaaaa n                                                        1991

<210> 547
<211> 592
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (320)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (341)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (479)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (502)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (541)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (566)
<223> n equals a,t,g, or c

<400> 547
ggcacgagcc aagggggagt cggcggcaca aaatggcggc ggcggcggcg gcggctggtg     60
ctgcagggtc ggcagctccc gcggcagcgg ccggcgcccc gggatctggg ggcgcaccct    120
cagggtcgca gggggtgctg atcggggaca ggctgtactc cggggtgctc atcaccttgg    180
agaactgcct cctgcctgac gacaagctcc gtttcacgcc gtccatgtcg agcggcctcg    240
acaccgacac agagaccgac ctccgcgtgg tgggctgcga gctcatccag gcggccggta    300
tcctgctccg cctgccgcan gtggccatgg ctaccgggca ngtgttgttc cagcggttct    360
tttataccaa gtccttcgtg aagcactcca tggagcatgt gtcaatggcc tgtgtccacc    420
tggcttcaag atakaakarg ccccaagacg catacgggac gtcatcaatg gttaacgcnt    480
tgacagttag agacaaaaga ancccggctt taatatggat aagatatgta attaagacca    540
nttaagggga aacagtttaa atggtntggg catgaaatct aaaaactaga ct            592

<210> 548
<211> 641
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (609)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (640)
<223> n equals a,t,g, or c

<400> 548
caagagccgg ctggttgtca ggatcctttg gttgcaagtg acagaaaacc catctcaaac     60
caccttcagt aagaatggga atttctctct gtttccctgg ggcagctgcc tcctgggtga    120
gggatgtagc tctaccacat ggtagtgggg gaggagtggt tcccagaagg aagcccccag    180
ggtgctggga ccagaagatg gggagggatg ccaggtggga gcatctcttt cccctgtgct    240
ggtgcctcga tcccagattg gaaggctttg ccttccccca agtcttgggt cccaggggag    300
ccccgttggc ccatggcctg cttgcagtgg ctcttggcct ttccatgtct gacctcagaa    360
tccttgctcc tatcctgcct ccttgggagg ccttccttga cttattccag ctctccctgt    420
ggatgtcatt atgaacactg gtgcccacat gtgtgaggaa ctgtgcccag tggacatttc    480
caagcaacat agccccccaa gaacctggtg gggaaggtgt tcctgcgttg cctgtttant    540
gtgtcgatga ggagcagagg ttcagaaagg ttcctgacta cccagagtca caagcatttt    600
ctcttctant gagattcagt ttgtgcattt gtcttcctgn a                        641

<210> 549
<211> 612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (51)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (510)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (513)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (530)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (567)
<223> n equals a,t,g, or c

<400> 549
aattcggcag agggagatta tggattctgt tatattccta ttaagaatat naantttgtg     60
ttttagcagg cagttaactt ggctgaactc aaattccaga ctcaatctcc ttatgttcag    120
ttcttttagt cttagcctgg cagcctagag ctcacctcat acatgcctaa tgcgggggtc    180
agccagagtt ttgagtggag tgtatgtaca gagtttgtgg ttctccctct gtggttctct    240
ccttctggaa tttttccctc actttccagc tggtttggca gtcacgaata ctgtcttttg    300
tgtgtttcct caaccaaaaa gactgcargt ttctatccag agtatctcct ttcggattgg    360
sttttatccc tgtggggrat ctgcaaatgc cccmagggrg gaaatggrgr tatatgctgg    420
gytcatttca awgkgcctcc ctcccttaca ggattctgcc tccttcagtg ctgcctgcct    480
aagttgatct ccattgtact taaacagtgn tanctgtggt ttaacccagn ttttgtagtt    540
gttctcagca agggggattg gtctganaca agctaattcc ctaggggcca aaagccaagg    600
gtcccggggc cc                                                        612

<210> 550
<211> 1065
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (573)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (746)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (785)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (799)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (807)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (898)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (921)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (961)
<223> n equals a,t,g, or c

<400> 550
ggatacttgg tcaggacctg gtggctttac cagatgatcc tctccacagt gactgtcccc     60
tttatcctgt gctgttgggt gctcccagag acaccttttt ggcttctctc agagggacga    120
tatgaagaag cacaaaaaat agttgacatc atggccaagt ggaacagggc aagctcctgt    180
aaactgtcag aacttttatc actggaccta caaggtctgt tagtaatagc cccactgaag    240
ttcagaagca caacctatca tatctgtttt ataactggag cattacgaaa aggacactta    300
ccgtttggct aatctggttc actggaagtt tgggattcta ctcgttttcc ttgaattctg    360
ttaacttagg aggcaatgaa tacttaaacc tcttcctcct gggtgtagtg gaaattcccg    420
cctacacctt cgtgtgcatc gccatgggac aaggtcggga ggagaacagt cctggcctac    480
tctcttttct gcagtgcact ggcctgtggt gtcgttatgg tgatccccca gaaacattat    540
attttgggtg tggtgacagc tatggttgga aantttgcca tcggggcagc atttggcctc    600
atttatcttt atacagctga gctgtatcca accattgtaa gatcgctggc tgtgggaagc    660
ggcacgatgg tgtgtcgcct ggccagcatc ctggcgccgt tctctgtgga cgtcagcagc    720
atttggatct tcataccaca gttgtntgtt gggactatgg cctccctgag tgagtgttac    780
actanacttc cagaaccgnt gggaacngct agcactactt ggaggagctg caaactgagc    840
agagatgaac gagctagcaa tcatcctcac tatatattgc tgaaaaagac gatcccanga    900
tctgctggta taagtcacac ngcttcactg gatatattcc ccatgtaggt tgttactcag    960
ntgtggtaaa ttaaatacat gtaagaatgc gaaaaatttg cgtcgtcggt ctccggtact   1020
gcacgattcc cctggcggcc tgggcgcggg gccccctctc atact                   1065

<210> 551
<211> 844
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (797)
<223> n equals a,t,g, or c

<400> 551
ggcaactgct gtgcggcctg cgggcgcgcg ctcccttatc ggccaacgga cgcgaggcgc     60
gcgccatgga acagcggtta gctgagtttc gggcggcgcg gaaacgggcg ggtctggcgg    120
cccaaccccc tgctgccagt cagggcgcac aaaccccagg agagaaggcg gaagcagcag    180
cgactctaaa ggcagcccca ggctggctaa agcggttcct ggtatggaaa cctaggcccg    240
cgagtgcccg ggcccagccc ggcctagttc aggaagcggc tcagccccag ggcagcacat    300
cagagacacc atggaacaca gccattcctc tgccgtcgtg ctgggaccag tctttcctga    360
ccaatatcac cttcttgaag gttcttctct ggttggtcct gctgggactg tttgtggaac    420
tggaatttgg cctggcatat tttgtcctgt ccttgttcta ttggatgtac gtcgggacac    480
gaggccctga agagaagaaa gagggagaga agagcgccta ctctgtgttc aatccaggct    540
gtgaagccat ccagggcacc ctgactgcag agcattggag cgcgagttac agttgagacc    600
cctggcaggg agataggacc cagctgtgct gtcatgcagc taacctctga tgtggtcttc    660
ctcaccattg gctatggatt tgatttcagg tgtataggac taagggcagc ttgcgggtta    720
gctctgtgac tgcataattt ttctaccttc tttccctgat ctttgctgcc atttgatctt    780
tgataatttt tgtgaantct ctaaaataca ttcactgtgg gtccgacgca atttattaaa    840
aatt                                                                 844

<210> 552
<211> 770
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (757)
<223> n equals a,t,g, or c

<400> 552
tcgacccacg cgtccgggcc gccgtagcgc gtcttgggtc tcccggctgc cgctgctgcc     60
gccgccgcct cgggtcgtgg agccaggagc gacgtcaccg ccatggcagg catcaaagct    120
ttgattagtt tgtcctttgg aggagcaatc ggactgatgt ttttratgct tggatgtgcc    180
cttccaatat acaacaaata ctggcccctc tttgttctat ttttttacat cctttcacct    240
attccatact gcatagcaag aagattagtg gatgatacag atgctatgag taacgcttgt    300
aaggaacttg ccatctttct tacaacgggc attgtcgtgt cagcttttgg actccctatt    360
gtatttgcca gagcacatct gattgagtgg ggagcttgtg cacttgttct cacaggaaac    420
acagtcatct ttgcaactat actaggcttt ttcttggtct ttggaagcaa tgacgacttc    480
agctggcagc agtggtgaaa agaaattact gaactattgt caaatggact tcctgtcatt    540
tgttggccat tcacgcacac aggagatggg gcagttaatg ctgaatggta tagcaagcct    600
cttgggggta ttttaggtgc tcccttctca cttttattgt aagcatacta ttttcacaga    660
gacttgctga aggattaaaa ggattttctc ttttggaaaa aaaaaaaaaa aaaaacycga    720
gggggggccc gtwcccattc scccyatatg aattccnttt ttacaatccc               770

<210> 553
<211> 2739
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (119)
<223> n equals a,t,g, or c

<400> 553
ttgcgnccgc cgctcggagg agtggcggag gggccagggc tagccttcag cgaggatgtg     60
ctgagcgtgt tcggcgcgaa tctgagcctg tcggcggcgc agctccagca cttgctgans    120
agatgggagc cgcctcccgc gtgggcgtcc cggagcctgg ccagctgcac ttcaaccagt    180
gtttaactgc tgaagagatc ttttcccttc atggcttttc aaatgctacc caaataacca    240
gctccaaatt ctctgtcatc tgtccagcag tcttacagca attgaacttt cacccatgtg    300
aggatcggcc caagcacaaa acaagaccaa gtcattcaga agtttgggga tatggattcc    360
tgtcagtgac gattattaat ctggcatctc tcctcggatt gattttgact ccactgataa    420
agaaatctta tttcccaaag attttgacct tttttgtggg gctggctatt gggactcttt    480
tttcaaatgc aattttccaa cttattccag aggcatttgg atttgatccc aaagtcgaca    540
gttatgttga gaaggcagtt gctgtgtttg gtggatttta cctacttttc ttttttgaaa    600
gaatgctaaa gatgttatta aagacatatg gtcagaatgg tcatacccac tttggaaatg    660
ataactttgg tcctcaagaa aaaactcatc aacctaaagc attacctgcc atcaatggtg    720
tgacatgcta tgcaaatcct gctgtcacag aagctaatgg acatatccat tttgataatg    780
tcagtgtggt atctctacag gatggaaaaa aagagccaag ttcatgtacc tgtttgaagg    840
ggcccaaact gtcagaaata gggacgattg cctggatgat aamgctctgc gatgccctcc    900
acaatttcat cgatggcctg gcgattgggg cttcctgcac cytgtctctc cttcagggac    960
tcagtacttc catagcaatc ctatgtgagg agtttcccca cgagttagga gactttgtga   1020
tcctactcaa tgcagggatg agcactcgac aagccttgct attcaacttc ctttctgcat   1080
gttcctgcta tgttgggcta gcttttggca ttttggtggg caacaatttc gctccaaata   1140
ttatatttgc acttgctgga ggcatgttcc tctatatttc tctggcagat atgtttccag   1200
agatgaatga tatgctgaga gaaaaggtaa ctggaagaaa aaccgatttc accttcttca   1260
tgattcagaa tgctggaatg ttaactggat tcacagccat tctactcatt accttgtatg   1320
caggagaaat cgaattggag taatagaaaa tggaagatgg tgttgttaat aaaggcattt   1380
aatagataaa aacatctcca aaaaggattt tgaagctgat cctatttagt taaaaagata   1440
attttgcttt caacygtagg tccagaaaac taattattgg catcagtctg tgaaatagtc   1500
cattatttgt tgttaaaaat gcttcaaaag gttttcagtg tcagtctgag atgcctggta   1560
tataggagcc tttgggaaat acctattttt cagtattcca tgcatattrg atatcaccat   1620
gaagcaagag acatgcattc tataatcatg tagacactca gactcagggg aaaatacaag   1680
ttatatcctg aaagccttta aaactctatg gtaggatcaa agattcaaat ggtttcagag   1740
aggttttatt tcaattaatt tgttctagtg ctttcaagag caagtacatc aaaatgtaga   1800
aggtaaaatg tatgcaacac taatataaat tattccaagt ctttaaggag ccaaagaaaa   1860
aaaagatttc tcacagcttt ttgttctgtt ttgtatttca attaggaact tgcagtatta   1920
ttttgaaaac cattctaaaa taataggagt taggaaataa ataaagtttt gctagccctg   1980
ctaagttcag gcttagaggc ttatcgctaa gtrtaaactt caccagattc cacgaaaagc   2040
tggatagctt tttttctgac ttatgttgtg gttgcacccc tcacaaatgg cagaacagta   2100
tgtaaagctg gtaacacctc ggtttcagtg caccatgtgt ttgctttgtg aaggtgaaga   2160
atatgttggt ttagagaaag aaattggatg taattttatg caatttactt ttaaagacaa   2220
acataactat ttagcagaga atattttaat aaatgcaaaa caacagctgg actgctgtac   2280
atcaaggaca gattaactgg aaaacatatg ttccttatgt gtgattgaga gccattcaga   2340
aaagacttcc tttgtgttca gcctatactt ttccatatgg tataccttga aaaaaattag   2400
cacaccatgg ttatttttct accttttata aaagacagag cctgtttact catttagaag   2460
atagagaaaa ttggtctaaa attgaacatc ctagattcac actcccaagt cacttaaggt   2520
gatttgatgg tgaggaaaat gattgacaaa gcccaacaat gatctcagga attacatttt   2580
ccaacagacc aaaaaatgtt ttcatgtagc agcaatgcag atttggtgaa tatttaatat   2640
atattttagt atgtatttca ctttatgact gacaattaaa aaatattgtt tggccaaata   2700
gtaaacaccc ttttgaaacc aaaaaaaaaa aaaaaaaaa                          2739

<210> 554
<211> 1351
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (46)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (595)
<223> n equals a,t,g, or c

<400> 554
cctgccggta ccggtccgga attcccgggt cgacccacgc gtccgntgga atcccttctg     60
cagcacctgg atcgcttttc cgagcttctg gcggtctcaa gcactaccta cgtcagcacc    120
tgggaccccg ccaccgtgcg ccgggccttg cagtgggcgc gctacctgcg ccacatccat    180
cggcgctttg gtcggcatgg ccccattcgc acggctctgg agcggcggct gcacaaccag    240
tggaggcaag agggcggctt tgggcggggt ccagttccgg gattagcgaa cttccaggcc    300
ctcggtcact gtgacgtcct gctctctctg cgcctgctgg agaaccgggc cctcggggat    360
gcagctcgtt accacctggt gcagcaactc tttcccggcc cgggcgtccg ggacgccgat    420
gagsagacac tccaagagag cctggcccgc cttgcccgcc ggcggtctgc ggtgcacatg    480
ctgcgcttca atggctatag agagaaccca aatctccagg aggactctct gatgaagacc    540
caggcggast gctgctggag cgtctgcagg aggtggggaa ggccgaagcg gagcncccgc    600
caggtttctc agcagcctgt gggagcgctt gcctcagaac aacttcctga aggtgatagc    660
ggtggcgctg tttgcagccg ccttttgtct cgtcggcccc aagaagagtt ggaacccggc    720
atccacaaat cacctggaga rgggagccaa gtgctagtcc actggcttct ggggaattcg    780
gaagtctttg ctgccttttg tcgcgccctc ccagccgggc ttttgacttt agtgactagc    840
cgccacccag cgctgtctcc tgtctatctg ggtctgctaa cagactgggg tcaacgtttg    900
cactatgacc ttcagaaagg catttgggtt ggaactgagt cccaagatgt gcccygggag    960
gagttgcaca ataggtttca aagcctctgt caggcccctc cacctctgaa agataaagtt   1020
ctaactgccc tggagacctg taaagcgcag gatggagatt ttgaagtacc tggtcttagc   1080
atctggacag acctcttatt agctcttcgt agtggtgcat ttaggaaaag acaagttttg   1140
ggtctcagcg caggcctcag ttctgtatag gcaatgctgt gttattactt gaatatagaa   1200
tatatagttt acaaaatgaa aattacaatg ttctcaccaa atatatgcct tcgtgtgtcc   1260
aaagtataat tattttagat gctaattttg aatagtttat taaacagtta taaatatgca   1320
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa t                                  1351

<210> 555
<211> 417
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (369)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (399)
<223> n equals a,t,g, or c

<400> 555
ttggcgggcc gcgtagcgga catggcgggc tcccggctcc cgcggcagct cttcctccag     60
ggcgtggcgg ccgtcttcat gtttgctttc gcttccctct acacgcaaat cccaggcctg    120
tatggccccg agggcatcct acctgcaagg aggacgctgc ggcctcaggg caaggggcgc    180
tggcagcagc tgtgggagac cccgacgctg ctgtgggaag cgccgagact ggggctggac    240
acggcccagg gcctggagct gctgagcctg ctgggtgcac tagtggccct gggagccctg    300
ctgctgagcc cactgcgcca ccctgtcatc tacttgctgc tttgggccgc tacctgcagc    360
ctgccaggng gccaggtgtc ctttatttca gggggactnc ctgctgctag agactgg       417

<210> 556
<211> 578
<212> DNA
<213> Homo sapiens

<400> 556
aggagacaga gaaacttggg tgtgtgatgc tcaccaaata cctacctgtt ttgggtagga     60
gccaaacagc atgaattaca agtgaactca atgcagctgc tgtactacca ggctccgatg    120
tcatctgcca tgttgctggt tgctgtgccc ttctttgagc cagtgtttgg agaaggagga    180
atatttggtc cctggtcagt ttctgctttg cttatggtgc tgctatctgg agtaatagct    240
ttcatggtga acttatcaat ttattggatc attgggaaca cttcacctgt cacctataac    300
atgttcggac acttcaagtt ctgcattact ttattcggag gatatgtttt atttaaggat    360
ccactgtcca ttaatcaggc ccttggcatt ttatgtacat tatttggcat tctcgcctat    420
acccacttta agctcagtga acaggaagga agtaggagta aactggcaca acgtccttaa    480
ttgggttttt gtggagaaaa gaatgttgtc ccaagaagat aaaaaatatt gttaagtgtg    540
caagttatta aaaaaaaaaa aaaaaaaaaa aaaaaaaa                            578

<210> 557
<211> 1354
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1298)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1310)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1318)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1339)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1346)
<223> n equals a,t,g, or c

<400> 557
gcgrccgcgg gassttcccg ggcctggccg tggaaccagg cagcaacctg gacatggaag     60
atgaggagga ggaagagctg accatggaga tgtttgggaa cagctccatc aagtttgagc    120
tggacatcga gcccaaggtg ttcaagccgc cgagtagcac agaggccctg aatgacagcc    180
aggagttccc cttccccgag acgcccacca aagtgtggcc gcaggacgag tacatcgtgg    240
agtactcact agagtatggc ttccttcgcc tgtcgcaggc cacccgccag cgcctgagca    300
tccccgtcat ggtggtcacc ctgggtgagt ctgagctgct gggcttgggg agctccatgg    360
cggggcctcc cctcctccct cgggtctcct cctgctggtg cgggrcsggg ggctgtgcag    420
gaagcactgg ggtctgcccc gccccaggca cgcttcccag ggctggggtc ctggatgggt    480
ttcctaagaa tgggcagggc aggaagcagg ccaggcctca gcaatggagc cagctggggc    540
agggcccagg gggtggcctg ggcggggctc ccggctccct gattcaccca cccgcagacc    600
ccacgcggga ccagtgcttc ggggaccgct tcagccgcct gctgctggat gagttcctgg    660
gctacgatga catcctcatg tccagcgtga agggcctggc cgagaacgag gagaacaagg    720
gcttcctgcg gaatgtggtg tcgggcgagc actaccgctt tgtgagcatg tggatggcgc    780
ggacgtccta cctggccgcc ttcgccatca tggtcatctt cacgctgagc gtgtccatgc    840
tgctgcggta ctcacaccac cagatcttcg tcttcatcgc gcccctgctg accgtcatcc    900
tggccctcgt cgggatggag gccatcatgt cggagttctt caacgacacc accaccgcct    960
tctacatcat cctcatcgtg tggctcgcgg accagtatga cgccatctgc tgccacacca   1020
gcaccagcaa gcggcattgg ctgcggttct tctatctcta ccacttcgcc ttctatgcct   1080
atcactaccg cttcaatggg cagtatagca gcctggccct ggcaccttct ggctcttcat   1140
ccagcattcc atgatctact tcttccacca ctacgagctg cctgcatcct gcascaggtc   1200
cgcatccagg aratgctgtt cargcgccgc actgggcccc gggaccccca cggcgctgcc   1260
gatgacatga acaacaactc gggcgccccg gctacagncc ctgactctgn cgggcagncc   1320
cccggccttg ggccctgtnt cggccngggg ccaa                               1354

<210> 558
<211> 3110
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1048)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2933)
<223> n equals a,t,g, or c

<400> 558
ggcagagtga gaagaaggga ccatagatgt taccgacttc ttgtccatga cccagcagga     60
ttcccacgct ccactcaggg actcaagggg gagttccttt gagatgacag atgacgacag    120
tsccattagg gctctgaccc agtttccact tcccaagaac cttctggcca aggtgattca    180
gattgcaacg tcatcctcca cagctaagaa cctcatgcag ttccatactg tgggcaccaa    240
gaccaagctg tctacactca ccctgctctg gccctgcccc atgacctttg ttgccaaagg    300
gcgccgcaaa gcagaggctg agaataaggc ggcagccttg gcctgcaaga aactgaagag    360
cctgggcctg gtggacagga acaacgaacc gcttacacac gccatgtata acctggcctc    420
tttgcgtgag ctgggtgaga cccagcgccg accatgcacc atccaggtgc ccgagcccat    480
cctccgcaag atagagacct tcctgaacca ttaccctgtg gagagttcat ggatcgcccc    540
agaactccgg ctgcagagtg atgacatctt gcccttgggc aaggactcag ggcctctgar    600
tgaccctatc acaggcaagc cctatgtgcc cctgttggaa gcagaggagg tacgtctcag    660
ccagagtctg ctagaactgt ggcggcggcg agggccggtc tggcaggagg ccccccagct    720
acctgtggac ccacatcggg acaccatcct caacgccatt gagcagcacc cggtggtggt    780
catctctggg gacacgggct gtgggaagac cacgcgcatc ccccagctgt tgctggagcg    840
ctatgtgacc gagggccgag gtgcccgctg caatgttatc atcacccaac ctcgccgcat    900
ctctgctgtg tctgtggcac agcgggtcag ccacgaactg ggcccctccc tgcgccggaa    960
tgtgggcttc caggtgcggt tggaaagtaa gcccccatcc cgaggcgggg ccctgctctt   1020
ctgcactgtg ggtatcctgc tgcgtaanct gcagagcaac cccagcctgg agggcgtgag   1080
ccacgtcatc gtggatgagg tgcatgagcg ggacgtgaac acagactttc tgctgatcct   1140
gctcaagggc ctgcagcggc tcaacccggc cctgcggctg gtgctcatga gtgccacagg   1200
ggacaatgag cgcttctccc gatactttgg tggctgcccc gtcatcaagg tgcctggctt   1260
catgtaccca gtcaaggagc actacctaga ggacatcctg gccaagttgg gcaagcacca   1320
gtacctgcac cggcaccggc accatgagtc tgaggatgaa tgcgcactcg atttggacct   1380
tgtgactgat ctggttctgc acatcgatgc tcgcggggaa ccaggtggga tcctgtgctt   1440
cctgcctggg tggcaggaga tcaaaggagt gcagcagcgc ctccaggagg ccctgggcat   1500
gcacgagagc aagtacctca tcctgccagt gcactccaac atccccatga tggatcagaa   1560
ggccatattc cagcagcctc cagttggggt gcgcaagatt gtcttggcca ccaacattgc   1620
tgagacttcc atcacaatca atgacatcgt gcatgtggtg gacagtgggc tgcacaagga   1680
agaacgctat gacctgaaga ccaaggtgtc ctgcctggag acagtgtggg tatcaagagc   1740
caatgtgatc cagcgccggg gccgggcggg ccgctgccag tccggctttg cctaccactt   1800
gttccctcga agccggctgg agaaaatggt ccctttccaa gtgccagaga tcctgcgcac   1860
acctcttgag aacctggtgc tgcaagcgaa aatccacatg cctgagaaga cggcggtgga   1920
gttcctgtcc aaggctgtgg acagtccaaa catcaaggca gtggacgagg ctgtgatctt   1980
gctccaggag atcggggtgc tggaccagcg ggagtacctg actaccctgg ggcagcgcct   2040
ggctcacatc tccaccgacc cccggttggc caaggccatt gtgttggctg ccatcttccg   2100
ttgcctgcac ccactactgg tggtcgtttc ctgcctcacc cgggacccct tcagcagcag   2160
cctacagaac cgggcagagg tggacaaggt gaaagcactg ttgagccatg acagcggcag   2220
tgaccacctg gcctttgtgc gggctgtcgc cggctgggag gaggtgctgc gttggcagga   2280
ccgcagctcc cgggagaatt acctggagga aaacctgctg tacgcaccca gcctgcgctt   2340
catccacgga ctcatcaagc agttctcaga gaacatttat gaggccttcc tggtggggaa   2400
gccctcggac tgcaccctgg cctccgccca gtgcaacgag tacagtgagg aggaggagct   2460
ggtgaagggc gtgctgatgg ccggcctcta ccccaacctc atccaggtga ggcagggcaa   2520
ggtcacccgg caggggaagt tcaagcccaa cagcgtcaca tataggacca aatcaggcaa   2580
catcctgctg cacaagtcga ccattaacag ggaggccaca cggttacgga gccgatggct   2640
gacgtatttc atggcagtca agtccaatgg cagcgtcttc gtccgggact cctctcaggt   2700
gcacccgcta gctgtgctgc tgctgaccga cggggacgtg cacatccgtg atgacgggcg   2760
ccgggccacc atctcactga gcgacagtga cctgctgcgg ctggagggtg actcgcgtac   2820
cgtgcggctg ctgaaggagc tgcggcgggc cctgggccgc atggtggagc ggagcctgcg   2880
cagcgagctg gctgcacttc cccccagcgt acaggaggag cacgggcagc tsnttgcgct   2940
actggcagag ctgctgcgag gaccctgtgg cagctttgat gtgcgcaaga cagctgacga   3000
ctgagccctg cttctgctgg ggctgtgtac agagtgcaaa tgtttattta aaataaagtt   3060
ctatttatcc cttgtgaaaa aaaaaaaaaa aaaaaaaaaa aaaactcgag              3110

<210> 559
<211> 987
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (978)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (983)
<223> n equals a,t,g, or c

<400> 559
acataatcag cgcactagta gggaaagctg gtcacctgca ggtaccaggt ccggaattcc     60
gggtggagca cgcgtccggg acgtgagaga cggtgtgaag agagttcgcc tgagccagat    120
cccaggtttc actgaagaaa cttcttagag attcattgca cttctgagat ttaatgttta    180
caacttggag ttgtcgacct tcttataaga tacattttgg aagtcaaaat gaaagttttc    240
tgtgaagttt tagaagagtt atacaagaag gtacttcttg gagccacact tgaaaatgac    300
agccatgatt acrtctttta tctcaaccca gcagtttcag atcaagattg ttctacagcc    360
acctccttag aatgggcaaa cacctgtggt atccagggca ggcatcagcc catctctgtt    420
ggtgtggctc ccattgctgt agcacctgtg tgtttgaaga ccaactctca gatgagcggt    480
tccagagaag taatgctcct tcagttaaca gtgatcaaag tgatgacaac ccggatattg    540
tctgtcaaaa ccgagttcca tgcaaaggag cagtacagag atgtaattaa aattctctta    600
gaatcagcca aagtcgattc taaattaatc tgcatgttcc aaaattcaga taaattgtta    660
tctcacatgg ctgcacagtg ccttgcattg cttctatatt tccaattgag agaaaagata    720
accttaagta attcctggat tgctttttgc cagaaaaatc tttctgaata ctctgagagt    780
aataaagcaa tatactgcct ctggactctt acagcaataa taaaaggaaa tctttaaagg    840
attcatgttc acaggaaaac aggaaattct aaaggcagtt cctggacttc atttcgacac    900
cctttttgga ggtgttttta caattccctt attctctcag gccttttgga aaactgcccc    960
gggggtactt cctaaaangg gtnaacc                                        987

<210> 560
<211> 2318
<212> DNA
<213> Homo sapiens

<400> 560
taggaatttt gcacgaggca ggaccggcga cccggcccgt ggagccggcg cgggcgggct     60
gctgaggtgg ctgtcgccgg ctccgagctg cggccgagcc cccgatggag gccgaggccg    120
cggacgctcc cccgggcggg gttgagtcgg cgctcagctg cttctctttc aaccaggact    180
gcacatccct agcaattgga actaaagccg ggtataagct gttttctctg agttctgtgg    240
agcagctgga tcaagtccac ggaagcaatg aaatcccgga cgtctacatc gtggagcgcc    300
tcttctccag cagcctggtg gtggtagtca gtcacacaaa accacggcag atgaacgtgt    360
atcacttcaa gaaaggcaca gagatctgta attacagcta ctccagcaac atcttgtcca    420
taaggctgaa ccggcaaagg ctgctggttt gcctagaaga gtccatttat attcacaaca    480
ttaaagacat gaagctgttg aagaccctcc tggatattcc tgcaaaccca acaggtctat    540
gtgctctctc tatcaaccat tccaattctt acctggccta tcctggaagc ctgacttcag    600
gggagattgt gctttatgat ggaaactccc tgaaaacagt ctgcactatt gctgcccatg    660
agggaacact agctgccatc accttcaatg cctcaggctc caaactagca agtgcgtctg    720
aaaaaggcac agtcatccgg gtgttctctg tccctgatgg gcaaaagctc tatgagttcc    780
ggagagggat gaaaaggtat gtgacaatca gctctctagt gttcagtatg gattcacaat    840
tcctctgcgc ctccagtaac accgagacgg tacacatctt caagctggaa caggtcacca    900
acagtcgacc agaagagcct tcgacctgga gtggctacat gggaaagatg tttatggctg    960
ctaccaacta cctccctacc caggtgtcag acatgatgca tcaggacagg gcttttgcca   1020
ctgcacgctt gaacttctcc ggacagagga acatctgtac cctctcaacg atccagaagt   1080
tgccacggct gctagttgcg tcatccagtg gacaccttta tatgtacaat ttggatcctc   1140
aggatggagg agagtgtgtc ttaatcaaaa cccacagctt gcttggctca ggaacaacag   1200
aagagaataa agaaaatgac ctcagacctt ccttacctca gtcttatgca gcgaccgtag   1260
ccagaccaag tgcatcttca gcctccacgg tgccaggtta ttctgaggac ggcggggcgc   1320
tgcgaggaga agttattcct gaacatgagt ttgcgacggg accagtgtgt cttgatgatg   1380
agaatgagtt tcctcctata atcttgtgcc gtggaaatca gaagggcaaa acgaagcagt   1440
catgatgaga agcacacctc agaaatcagg acatcccccc tatcaggtgg ttttggagaa   1500
aacaaggaag gcggaagaat ggagtgcaat tgtgtgagca gaaagggggg caggaatccc   1560
gggtgctcca ctgcttaaac cacaggacct ggttaactcc tcaccaagct tcccacgacc   1620
ctggttgcca atgggcgcgg gagacattgt atacacatca tgctatttaa aatacgttca   1680
aactatagtg taaatgctaa ttaaccatat tggtatataa ccggaatttt atattaaaag   1740
gggcctcctt tttaaatata tgccgtgtaa aaaatgtact tataggaaca tctctttgaa   1800
ttgtatttct tgtatattac atacttagag agagactctt ttagccaggc aaagtctttt   1860
ttggctgtgg ctggaataaa tcatttatta cttgggagtc ccattttgga cactaataat   1920
aaaatcatgg caatgcattt ttgaggtttt tatatttttt ttgtttcctt gtggttatag   1980
gggacaggag gaactcttta acttctttta aatgcagtca tttcaccctt aaaaggagag   2040
gaaggggatt gggccacaga cttatccatg gactcgtctg ctctgagatc tggaaaacga   2100
cctaactttg gtctaaatct gtgctcctca aggcattgtt tgatagaaat gtaggatttc   2160
aggatctact cgagccctac tgagacggaa tccggattct cacaagatcc caggtgattt   2220
gtttgcatat taaagatgga gaccagtgag tacactggtt tgtggaagga aaaaaagaga   2280
aaagagagag aagctctgcc ctaaatacta attagaat                           2318

<210> 561
<211> 1292
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (534)
<223> n equals a,t,g, or c

<400> 561
gagtgactcg cgactggtcg gcgcggcgaa agcagagcgg cgcgccggtt ccttggttcc     60
tgagggcgat ggcgcggggt ggctggcgcc ggctacgccg cctgttatcc gcggggcagc    120
ttctattcca gggccgcgcg ctgctcgtca ctaacacgct gggctgcggc gcgctcatgg    180
cggccggtga tggcgtgcgc cagtcctggg agatccgcgc ccggcccggc caggttttcg    240
acccacggcg ctccgcgagc atgtttgcgg tgggctgcag crtgggtccc ttcctgcact    300
actggtactt gtcgctggac cgcctattcc ctgcgtctgg cctccgaggc ttcccaaatg    360
tcctcaagaa ggtcctcgtg gatcagctgg tagcctctcc attgctgggc gtctggtact    420
tcttgggcct tggctgcctg gagggtcaga cagtgggtga gagctgccag gagctgcggg    480
agaagttctg ggaattctac aaggcagact ggtgcgtgtg gcctgctgcg catntcgtga    540
acttcctctt cgtgcccccy caatttcgag tcacctacat caacggcctg acgctgggct    600
gggacacgta cctgtcctac ttgaagtacc ggagcccagt tcctctgaca cccccaggct    660
gtgtggccct ggacacccga gcagactgaa ctgtctgctt cctggaccag atgcaagact    720
gtctcctggc ggaccamccc ctctgacara aggggaatgg gctcctgcag caagctcggg    780
tcttgagcca cgtcccagca ccacttcagc tccggagcat tgggctgagc cgccctttcc    840
aagctcactt ctgggactga gtttcctcaa ccggaacaca cccatgaaga tggatgatca    900
tcccctagcc cttctcagca ggaacctcat gygacctgtg accaagatgt cccatcctca    960
gcacagggcc cactctgcca accagtctca agcaccagcc cctcaacact gccatccacc   1020
tggctctggg ccaagccacc aatccagagc tccctcaggt cctgggacta aggcggggac   1080
atgactgatc ccctcagagc aggctcaggc ctggagtcgg cccccaaaag tttcacatag   1140
ggccaggcag cctctgtgtt tctttccctg gtcctgaact gtggaaatgc cattaaactc   1200
tctctataat gtaactgaaa ctgctggctg ggcgcagtgg ctcccacctg taatctcagc   1260
ccttcccgag gctgaggtgg aaggattgct cg                                 1292

<210> 562
<211> 966
<212> DNA
<213> Homo sapiens

<400> 562
cggcgctgag gacgcacgga tgccttccgt gccttccatc aagatctcaa ttttgtgcgc     60
aagttcctac agcccctgtt gattggagag ctggctccgg aagaacccag ccaggatgga    120
cccctgaatg cgcatggtcg aggacttcga gccctgcacc aggcagccga ggacatgaag    180
ctgtttgatg ccagtcccac cttctttgct ttcctactgg gccacatcct ggccatggag    240
gtgctggcct ggctccttat ctacctcctg ggtcctggct gggtgcccag tgccctggsc    300
cgccttcatc ctggccatct ctcaggctca gtcctggtgt ctgcagcatg acctgggcca    360
tgctccatct tcaagaagwc ctggtggaac cacgtggccc agaagttcgt gatggggcag    420
ctaaagggct tctccgccca ctggtggaac ttccgccact tccagcacca cgccaagccc    480
aacatcttcc acaaagaccc agacgtgacg gtggcgcccg tcttcctcct gggggagtca    540
tccgtcgagt atggcaagaa gaaacgcaga tacctaccct acaaccagca gcacctgtac    600
ttcttcctga tcggcccgcc gctgctcacc ctggtgaact ttgaagtgga aaatctggcg    660
tacatgctgg tgtgcatgca gtgggcggat ttgctctggg ccgccagctt ctatgcccgc    720
ttcttcttat cctacctccc cttctacggc gtccctgggg tgctgctctt ctttgttgct    780
gtcarggtcc tggaaagcca ctggttcgtg tggatcacac agatgaacca catccccaag    840
gagatcggcc acgagaagca ccgggactgg gtcagctctc agctggcagc cactgcaacg    900
tggagcctca cttttcacca amtggttcag cgggacttma amtttccaga tcgrgsacca    960
cctctt                                                               966

<210> 563
<211> 1092
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (57)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (227)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1078)
<223> n equals a,t,g, or c

<400> 563
ggtgtcttcc caggaggagt tgctgggccg actctgccag gcatctgtgt ccctggnagg     60
gtcttcccca acacaccctg catgacacct tcgtcactaa aatcagcctc gtgagctggc    120
aggcaaggac cctgttcctt tactcagctg agaaaaccag agagggtggt ggcctgtcct    180
gggctctgag gcaaatcagg cagaagggtt ggatgcctga ggtcctnctc ccacccacca    240
ggcctccaga cctccgggca cctggagacc tctcggtatc gctctgccct cctctgcagg    300
atttgctctg ggccgccarc ttctatgccc gyttcttctt atcctacctc cccttctacg    360
gcgtccctgg ggtgctgctc ktstttgttg ctgtcagggt cctggaaagc cactggttcg    420
tgtggatcac acagatgaac cacatcccca aggagatcgg ccacgagaag caccgggact    480
gggtcagctc tcagctggca gccacctgca acgtggagcc ctcacttttc accaactggt    540
tcagcgggca cctcaacttc cagatcgagc accacctctt ccccaggatg ccgagacaca    600
actacagccg ggtggccccg ctggtcaagt cgctgtgtgc caagcacggc ctcagctacg    660
aagtgaagcc cttcctcacc gcgctggtgg acatcgtcag gtccctgaag aagtctggtg    720
acatctggct ggacgcctac ctccatcagt gaaggcaaca cccaggcggg cagagaaggg    780
ctcagggcac cagcaaccaa gccagccccc ggcgggatcg atacccccac ccctccactg    840
gccagcctgg gggtgccctg cctgccctcc tggtactgtt gtcttcccct cggccccctc    900
acatgtgtat tcagcagccc tatggccttg gctctgggcc tgatgggaca ggggtagagg    960
gaaggtgagc atagcacatt ttcctagagc gagaattggg ggaaagctgt tatttttata   1020
ttaaaataca ttcagatgta aaaaaaaaaa aaaaaaaaac tcgagggggg gccccggnaa   1080
ccaattcgcc ct                                                       1092

<210> 564
<211> 673
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (669)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (671)
<223> n equals a,t,g, or c

<400> 564
gaaaaaagaa ggaactctcc ctgggctctt tgttgaagtt gagcctgtac ttctctgctg     60
gtttgctgcc ctatgtccac cttcccatct catcttacct taatcacgcc cggtggacct    120
ggggagacca gacaacactg caaggatttt tgacacattt tctcagggaa gaatatggaa    180
ccttcagcct ggccaaatct gaaataggat ccagtatgtc tgaaatactg ctttctcaag    240
taacaaatat gaggaccgaa ctctcattca acatccaagc ccttgcagtt tgtgcaaata    300
tatgtttagc aacaaaggac agacagaatc catcattagt atggcttttt actggaatgt    360
wttgcattta ttcattgttc tttgcttgga gagcaaattt agatatttca aaaccacttt    420
tcatgggtgt ggtggaacga wtctggatgc akagcaatgc agtagtggcc gcctcgctgg    480
cattggttkg gctgcarttg tgtctgagac ttaaccgagt gctgaatagc aatggggctt    540
yagtgtctgg gaatgggctt tctgcaacyc tttttggtag tttacccaaa tatattctaa    600
ttacagaaaa ggaacatttg tttgcatagg gattcatgaa ggcgacccca cccggggaaa    660
aaggacctnt nca                                                       673

<210> 565
<211> 1612
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<400> 565
gggcatggcg tccgatcgag gcgggcgttc acgggcggcc agggttgagt cccgggtcgg     60
ggccggggga ttgccggcgc atcagggccg agggctgggg ctggcggggc cgctcgctgc    120
ctctcgctcg cagcagcggc ggcaggcgcg ggcgagggcc acggggagag gagacgcagc    180
cccgcgggtg gcacgctcgg ccgggccccg gcccgcgctc aacgggcgcg atgctcttct    240
cgctccggga gctggtgcag tggctaggct tcgccacctt cgagatcttc gtgcacctgc    300
tggccctgtt ggtgttctct gtgctgctgg cactgcgtgt ggatggcctg gtcccgggcc    360
tctcctggtg gaacgtgttc gtgcctttct tcgccgctga cgggctcagc acctacttca    420
ccaccatcgt gtccgtgcgc ctcttccagg atggagagaa gcggctggcg gtgctccgcc    480
ttttctgggt acttacggtc ctgagtctca agttcgtctt cgagatgctg ttgtgccaga    540
agctggcgga ncagactcgg gagctctggt tcggcctcat tacgtccccg ctcttcattc    600
tcctgcagct gctcatgatc cgcgcctgtc gggtcaacta gcctcaccga ggtgccggag    660
agggagcgct ggacaactag aatgttgacc tcgagccgag gccctacttg cagcgcaccg    720
gaggagaggc tctctagtct gaaggcaccg ccggcttgcg ccgagctgag tgccgggttt    780
ccctattcca atcctgtttg aaatggtttc ttcagcaggg cttaaaagag cagccttcat    840
cctgaaaatg tatttccttt tgtttaatgc tttgagtaga taatcctgaa ttgaggtcat    900
gaggaggccc cccaggccag acagtcctga acccctctga cacttggaaa ctgaatataa    960
gtaaaatgtc caggtggact ctgagtattt cctgtggatc ctgggaaagt actgttgcac   1020
aaaggctgca aagctggact caggaatgtc ctccaaccag cagcgctgac ctaagagctc   1080
cctgtgccgt ctatccagac cagacttcgg tagatgcctt tgttagatct atcacatgta   1140
aacgagcttg tatctccttc cctgtgccac gagagagatt ggctttttat tccagtctag   1200
gcagagacag aagaatgttg aataagagca cgattagagt cctgtctggt tatctgttgc   1260
ccaagaaaag aactctgctg tccaggcact gcttggctta ctatcccagc aaagactgca   1320
gttttgtgga cttttgacca ccttgggctg gcactcttag cacacctgag acagatttaa   1380
gcctccctaa gagactgaag agaggaacag gtgtcagata ctcataggca ctgagatcta   1440
caaatgggaa gcttgtgagt ggcccatctt tgttggccta cgaactttgg tttgatgcca   1500
gtcaggtgcc acatgagaac ctttgctgag atgcaaataa agtaagagaa tgttttcctg   1560
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagggcgg cc           1612

<210> 566
<211> 1034
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (975)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1034)
<223> n equals a,t,g, or c

<400> 566
aactggcaga gcctgggaag tccttcgraa ggggaccagg gcgtctraag tsctcagtgc     60
ccccactact ctraggccga ctccagctac tctraggccg actcaatctc tcggctggaa    120
gcagtgtttt cccagagctt ggcccttgct gacctcgctc actgggccca tcttcccaca    180
ctgctcttag aaggacaccc ctaccggtag cagccccaag ctgagggggc tccctttttg    240
accttcactg gcccgccctt cactgtctcc agcaggagtt cctagggctt ggcctgcctt    300
gctccacagt acggcggagg cagccctgct tgtcactgag gagccctaga caaggccaat    360
gggttcatca atgcccactg gctctctgcc aaagccaaaa aggtgtcagg cagtctccag    420
cgtgctggcc gggtctcgga tgccacccct gctcactgag cctgcatggg ccttgccccc    480
gaccctgtgg tctctgggat tggggtcggc ttaccctgta gcacagacag ggactcctgc    540
tgccctggga gctgtctcaa gcaaaatctc ttgtcccaga ggtgcccatg tgggtccgct    600
gtgtcccctg tcatcatcct tgttttttct cattttggcc aaggsaggct ccctgggaca    660
ggcagggaac aactgcggag atattagtga ttcataggtt tgtacagtgt tttatacttt    720
gcaaagcact ttattagctc acacctgtcc actyacatga aactcgtgtt aggccctggg    780
aggcgaccgg taactctcac cgtgccctca gatgaagcac agagaggttg ttacttgccc    840
gggccatcca gtgggctggc ygggtcttgt gtccccatct gtggacccct ctagggtctg    900
agatgagatg aagaagtgtc tcctgtatcc acctcttcct ggcctccctt cccccacttc    960
ctggtccctg tccantcctc aggttgggtg ctctcacttc ttgaaagctc taggcacccc   1020
cgcctcccgc cagn                                                     1034

<210> 567
<211> 2353
<212> DNA
<213> Homo sapiens

<400> 567
gtggctccaa actttacatc agcccacccg agatcgagaa aaggaaaagc gtcatcaaga     60
tcgtgctctg gccatctaca aacaagtact cagaaatgat gcaaagaatc tgtatgctgc    120
caatggcata ggagctgttt tggcccacaa aggatatttt cgtgaagctc gtgatgtatt    180
tgcccaagta agagaagcaa cagcagatat tagtgatgtg tggctgaact tagcacacat    240
ctatgtggag caaaagcagt acatcagcgc cgttcagatg tatgamaact gcctccgaaa    300
gttctataag caccaaaaca ctgaagttgt actctatttg gcccgggccc tcttcaagtg    360
tggcaagtta caggaatgca aacagacttt gctgaaggct agacatgtgg cacccagtga    420
tacagttctt atgtttaatg tggccttggt cctgcaaaga ttagctacct ctgtcctgaa    480
agatgaaaaa agtaatctga aggaagtact taatgctgtg aaagaactgg agcttgcaca    540
tagatacttc agttatttga gtaaagtggg agataaaatg agatttgatt tggcccttgc    600
tgctacagaa gccaggcagt gttctgactt actgagccag gcccagtacc atgtggcccg    660
ggcacgcaaa caagatgaag aagagcggga gctgcgggcc aagcaagagc aagaaaagga    720
gctgttaagg cagaaacttc ttaaagaaca ggaagagaaa cgtctcagag aaaaggaaga    780
gcaaaagaaa cttttggaac agcgggccca gtatgtggag aagaccaaaa atattcttat    840
gtttactggt gagactgaag caacaaaaga gaagaaaaga ggtggtggtg gtggacggcg    900
ttctaagaag ggaggagagt ttgatgaatt tgtcaatgat gacactgatg atgacctacc    960
tatatccaaa aagaagaaga gaagaaaggg tagtggcagt gaacaagaag gtgaagatga   1020
ggagggtggt gagagaaaga agaaaaagag gagaagacat ccaaagggag aagaaggatc   1080
tgatgatgat gaaacagaaa atggccccaa accaaaaaaa cgacgtccac caaaagcaga   1140
gaagaaaaag gctcccaagc cagaacgtct gcctccatca atgaagggaa aaataaaatc   1200
caaagccata atttcatcaa gtgatgactc ttcggatgag gataaactta aaattgctga   1260
tgaaggacat cccaggaaca gcaacagcaa cagtgactca gacgaggacg aacaacgaaa   1320
gaaatgtgcc tcatcagaga gtgattccga tgagaaccag aacaagtctg gcagcgaggc   1380
cggcagtccc cggaggccac gaagacagcg gtcagatcag gactcagaca gtgaccagcc   1440
atccagaaag agaaggccct ccggttctga gcagtctgac aatgaatctg tgcagtcagg   1500
gagaagccac tcaggagttt ctgagaacga ctctcgccca gcttctccaa gtgccgaatc   1560
agatcacgaa tcggagagag gatctgataa tgagggttct ggccaaggct ctggaaatga   1620
atcggaacca gagggatcca acaatgaggc ctcagataga ggctcagaac atgggtcaga   1680
tgatagtgac taggttttat ttcatcaata agcttcatct ctggaggaaa cttttttaat   1740
atatgaaagc tgtgataaaa atgtttcaga tgtttagtca attgtgaaat ttttcttaag   1800
gcaattttct tttctatcag tttgtatatt actaagcccc aagagacatt tcctgtgcta   1860
gagtccaata tttgagtctc tcgtgcaaat gagactattc tttgtggtac aattccacct   1920
atcatatgtg aaaactgcag taaaaataaa cccagatgct aaatcattcc tacaaaggtt   1980
tgactgaaac tgtggcagat gtctcatctt ctttatatgt taagcagcat actcttctga   2040
tttttattgc aatcttttac caagtggtgc acaaacttgg tattgatgtc tttattccat   2100
tttgagttta gattgagaat atttttattt tctgaaggca gagatatcta ctgtataatt   2160
gcaccaaagt acatttgaaa ggaaggtttt caatagtgta atactgcagc gatgtagata   2220
aaatcacaaa tgtataatgt gttaggttga ataaggtgtg gaaaatgctt ttctgttagt   2280
agaatgcaaa aacctaccta agccacataa taataaaatt cttttaccaa ctttaaaaaa   2340
aaaaaaaaaa aaa                                                      2353

<210> 568
<211> 1111
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> n equals a,t,g, or c

<400> 568
aaggtcggtt ggtttgcact ggcggacaaa tggtccaatt accgcggaaa agggacctct     60
gaatccagat tggcgtcctc tctacctata aggtaggctc aggggcggtg ataaccancc    120
cgtgatgtgg gcgcggcact ggaggtagaa ctgagagatc ctctaccgca gtcgtttgag    180
gaggcggaac tgaagttttt tcttaattat catgtgacgg gttctggatt taatgggggg    240
aaaagggcgg aaaaggacaa ggatccaaac tggcgaattt gctgatcttc gcgtccctct    300
ccgctttccg gccggcagcg ctgccagggt atatttcctt ttttccgatc ctgcaacagc    360
ctctttaaac tgtttaaatg agaatgtcct tggctcagag agtactactc acctggcttt    420
tcacactact cttcttgatc atgttggtgt tgaaactgga tgagaaagca ccttggaact    480
ggttcctcat attyattcca gtctggatat ttgatactat ccttcttgtc ctgctgattg    540
tgaaaatggc tgggcggtgt aagtctggct ttgaccctcg acatggatca cacaatatta    600
aaaaaaaagc ctggtacctc attgcaatgt tacttaaatt agccttctgc ctcgcactct    660
gtgctaaact ggaacagttt actaccatga atctatccta tgtcttcatt cctttatggg    720
ccttgctggc tggggcttta acagaactcg gatataatgt cttttttgtg agagactgac    780
ttctaagtac atcatctcct ttctattgct gttcaacaag ttaccattaa agtgttctga    840
atctgtcaag cttcaagaat accagagaac tgagggaaaa taccaaatgt agttttatac    900
tacttccata aaacaggatt ggtgaatcac ggacttctag tcaacctaca gcttaattat    960
tcagcatttg agttattgag atccttatta tctctatgta aataaagttt gttttggacc   1020
tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1080
aaaaaaaccg gggggggggc ccccccccca a                                  1111

<210> 569
<211> 767
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (374)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (645)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (670)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (671)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (725)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (726)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (740)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (759)
<223> n equals a,t,g, or c

<400> 569
aagctggagc tccaccgcgg tggcggccgc tctagaacta gtggatcccc cgggctgcag     60
gaattcggca cgagggcggg cgtgcgtgga gcgggggccg cggccgcgcc gcagagatgt    120
gactcgggcc gaagcagctg gagcgtcggc gctgcggggc cgcgggggtc gaatgttcgt    180
ggcatcagag agaaagatga gagctcacca ggtgctcacc ttcctcctgc tcttcgtgat    240
cacctcggtg gcctctgaaa acgccagcac atcccgaggc tgtgggctgg acctcctccc    300
tcagtacgtg tccctgtgcg acctggacgc catctggggc attgtggtgg aggcggtggc    360
cggggcgggc gccntgatca cactgctcct gatgctcatc ctcctggtgc ggctgccctt    420
catcaaggag aaggagaaga agagccctgt gggcctccac tttctgttcc tcctggggac    480
cctgggcctc tttgggctga cgtttgcctt catcatccag gaggacgaga ccatctgctc    540
tgtccgccgc ttcctctggg gcgtcctctt tgcgctctgc ttctcctgcc tgctgarcca    600
ggcattggcg ccgtgccgga aggcttggtg ccggcattgg gaacngggcc ccgcgggctt    660
gcaagctggn ngggccctgg cgcttgtgcc ctgaatgctt ggtgcaaagt caatcattcg    720
cttgnnggaa atggcttggn ggcttaaccc gtgcctgcnt tgaacac                  767

<210> 570
<211> 1350
<212> DNA
<213> Homo sapiens

<400> 570
cagtcagtgg cctctgctgg agacaaagcc tgcccagctg gtgaccagca agtgtcaggc     60
tgacgcccag gcccagcagt ggcagctgtt gccacacaca tgacggaggg attttcttga    120
agggtcagct attgcactgt gctgggaggc tggctgtggc tcctgtttgt gaagagaact    180
cccagttcct tttcacagcc gctgagaaca catccacaca tctaccccac ggccttgtct    240
tggaactgct cctgctatcc ccacaccctg cttcctcacc ccactggctc ttgggcaaat    300
gactgttggt accaggaccc tgggggtctc ccctaacaaa gcagaccagc ctggggcaga    360
tatacctacc acaggagccc cctgtctttc ataggccaag gatccacata cccatagagt    420
tcatggattc tagagggtct aggaatctct tgaaattgtc cctaaaatac tgcatgtgtg    480
tgcatacatg cattttcctg gggaaaaagt ccatggcttc taaaagaggt ccctgatccc    540
caaagggcct gaacctctgc tctggattga agccactgtc tgcccaagct gccaccccct    600
aatcttcctc cctggcgtgc tcaaactgcc atcgcctgct ccctccacac ggcccttggg    660
gtcagcagcc aagtgtctgt ggtccgcagc acctgctctg gagggctctc cagcagtttc    720
gcctcctgac tctcaccagc gtcctctcgg cagcactccc gtgcccaagt gcacccctct    780
ggacttgcca gcgcaggccc cttcgctccc agggccatgc tttgcctgtc ctctgtcgtg    840
atgtttcttc cgcagccagg tgcagcctca gawcccctgt tcatctggga agcctcctgc    900
cacagcttag gacagaactg ggcccagggc aaaggcctct ccccagagga tggactagaa    960
ggcctgggcc acactcgggc atggaccttt ggggctgggg agcmggggct gcgcctgttg   1020
aatgtaagag gactgctgac cagagggcct tcaagagggt ctctctgtcc tttgctgtgg   1080
tcagatcagg ctctgcactt atcagccggt cctttgtggc aacgcagccc tgttctgttt   1140
ttgcttttcc tcttcttgac caaagcatgt gccactagct gtccttgagg acctcgtctt   1200
tatgaaacac acacctggaa taaaaccact tcttacatgt mmacaaaaaa aaaaaaaaaa   1260
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1320
aaaaaaaaaa aaaaaaaaaa aagggggggc                                    1350

<210> 571
<211> 2551
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1315)
<223> n equals a,t,g, or c

<400> 571
tcgtgctgcg gaggccggat ttttccctgg tatgatttat ctcacctcgc aatggtttcc     60
gcagcgtaat cgcgccagca ttatggggct gttctatatg ggcgcaccgc tggcgttaac    120
actgggatca ccgctttccg gcgcgctgtt ggagatgcat ggatttatgg ggcatcccgg    180
ctggttctgg atgtttgtga ttgaaggatt gttggcagtc ggtgctgggg tattcacatt    240
cttttggctt gatgacacac cggagcaggc acgttttctg agtaaacaag aaaaaacgtt    300
gcttatcaat caactggcaa gtgaagaaca acagaaagtg acttctcggc tgagcgatgc    360
gctgcgtaat ggccgagtct ggcaactagc gattatctac ctgaccattc aggtggcggt    420
ttacggatta awtttcttcc tgccgaccca ggttgcggca ttgctgggaa caaaagtggg    480
ctttacagcg tcggtggtca ccgccattcc gtgggttgcg gccttgtttg ggacctggct    540
tattccgcgc tattccgata aaaccggcga acggcgtaat gtcgcagcgc tgacattact    600
ggcggcgggc attggtattg gtctgtccgg gctgctttct ccagtaatgg cgatcgtagc    660
gctgtgtgtt gcagctatcg ggtttattgc cgtgcagcca gtgttctgga cgatgccgac    720
acaactgctt tccggtacgg cgctggctgc gggaattggt tttgtaaacc tgtttggtgc    780
agtgggcggg tttattgccc cgatcctgcg cgtgaaagca gaaacgttat ttgccagcga    840
tgcggcggga ttactgacgc tggcagcggt ggcggtcatc ggttcgctga ttattttcac    900
tctgcgtgta aatcgcactg ttgcgcagac cgacgtggca catcattaaa taggttaagg    960
aacacgatga acgcattatt aagcaatccc tttaaagaac gtttacgcaa gggcgaagtg   1020
caaattggtc tgtggttaag ctcaacgact gcctatatgg cagaaattgc cgccacttct   1080
ggttatgact ggttgctgat tgacggggar cacgcgccaa acaccattca ggatctttat   1140
catcagctac aggcggtagc gccctatgcc agccaacccg tgatccgtcc ggtggaaggc   1200
aagtaaaccg ctgattaaac aagtcctgga tattggcgcg caaactctac tgatcccgat   1260
ggtcgatact gccgaacagg cacgtcaggt ggtgtctgsc acgcgctatc ytccntacgg   1320
tragcgtgkt tcggggccar kgtggcacgg gctgcgcgct ggggacgcat tgagaataca   1380
tggcgcaagt taacgattcg ctttgtctgt kggtscaggt ggaaagtwaa acggcactgg   1440
ataacctgga cgaaatcctc gacgtcgaag ggattgatgg cgtgtttatt ggacctgcgg   1500
atctttctgc gtcgttgggc tacccggata acgccgggca cccggaagtg cagcgaatta   1560
ttgaamccag tattcggcgg atccgtgctg cgggtaaagc ggctggtttt ctggctgtgg   1620
ctcctgatat ggcgcagcaa tgcctggcgt ggggagcgaa ctttgtcgct gttggcgttg   1680
acacgatgct ctacagcgat gccctggatc aacgactggc gatgtttaaa tcaggcaaaa   1740
atgggccacg cataaaaggt agttattgat atcaaaggcc catggggatc ggctgtgggc   1800
ctgtgttaat tagtggttat tcgctgccag atcggcttcg cttagctggg tggccgcgag   1860
cacctggtca cgatcaaagc cctgttccag catgcgcaaa gcaattttaa tggcttgttc   1920
atgcaaacct tctaatttac cttcctgcca gccaatttga tgtccttcct gccgcagccg   1980
ttcagcaata gtcattaatc tctcctttta atgacagttc ggaatatcag catcagtgag   2040
ttgggttgtc gccagcacaa tctcacgttc aaagccctgc tccagcatgc gcaaagcaat   2100
tttaatggct tgttcatgca taccttcctg ccagccaatt tgatgccctt cctgccgtag   2160
ccgtwcagca atagtcatta atctctcctt ttgtagtggt gaacgttcgg caatctcctc   2220
aataaaacgg gtgaaacggg aggtatcgcc gcattgcagc agataattaa acagtgtttg   2280
tagctggctg tcattagtga agcctctaac caaaagcgtg gtgatcctgt cgaccatgcc   2340
gattaaatcg cggtcgcgaa tatgcttttg aatcagttcc agcagagcta tacgccgatg   2400
ttgcatgatc tcatcgtcag gtacgatggt gatatccacc aacagaaaag cttcggtgta   2460
caactgccgg gcaagttgcg gatcgtcaaa ctcatccagc cagttgaggg ggggcccgga   2520
acccaatycg gcctatagtt aagcggtatc a                                  2551

<210> 572
<211> 1213
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (685)
<223> n equals a,t,g, or c

<400> 572
ggtgtgcagg tgaagaggaa ggtgcaggct ttaaaggcag acattgatgc tacattatat     60
gaacaagtca tcctggaaaa agaaatggga acttatttgg gcacctttga tgattacttg    120
gagttattcc tgcagtttgg ttatgtgagc cttttctcct gtgtttaccc attagcagct    180
gcctttgctg tgttaaataa cttcactgaa gtaaattcag atgccttaaa aatgtgcagg    240
gtcttcaaac gtccattctc agaaccttca gccaatattg gtgtgtggca gttggctttt    300
gaaacgatga gtgttatatc tgtggtcact aactgtgcgc tgattggaat gtcaccacaa    360
gtgaatgcag tctttccaga atcaaaagca gacctcattt tgattgtagt agcagtggag    420
cacgcactcc tggctttaaa gtttatactt gcatttgcca tacctgataa gccacggcat    480
atccagatga aactagccag actggaattt gagtctttgg aggcactcaa gcagcagcaa    540
atgaagctcg tgaccgagaa cctgaaggag gaaccaatgg aaagcgggaa ggagaaggca    600
acctgagtgc ccagcgtgcc cagctgccct gttggcagag gcctgtgtct gtgccacacc    660
tgccacggtg gcaggggggg taccnggggc agcatcgtgg ctcctgaacc cagacccaat    720
gcttagccaa acgaatggct cccatgtggc aagcaccctt ctcagtttcg cagtggcttg    780
gctcgggatc cttggcagtt cccccagccc caccctgtct gctccttccc agttccttcc    840
cgggccccac acgctgctcc agctgccaac tttgctgcag agccactgcc gcccttgagc    900
ctctcaccat gagtgagcca ccagctctcc acgttcccct catagcagtg tcactcccaa    960
ccccaccatg gcccagggac ccgtggacag gttggggatg gggtgtgtgc ccactgtgct   1020
catcacagga gcctcagttg agagtgagcg gggtacagta aggcagtgct tcccacactg   1080
gacctctttc ctggttctct tttgcaatac attaacagac cctttatcaa cataaacaat   1140
agtaactgag ctattaaagg caacctctct gacwaaaaaa aaaaaaaaaa aaaaaaaaaa   1200
aaagggcggc cgc                                                      1213

<210> 573
<211> 378
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (369)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (376)
<223> n equals a,t,g, or c

<400> 573
ccgatcctct ccgtgggagc cagcgagcct ctctccctga tcttacgtgc tcaaggatcc     60
agtttcacct atggaatgag aaagttgggg aagaagtcat ctagcgtctt gctactcaaa    120
gtgtggtcca tggacagcag catcagcatc acctgggatc ttcttggaag aaatgtagaa    180
actcaggcct caccccagaa tctgcctttt tataagaccc ccagaagctg ttgtgaaggc    240
agagcagcat ctgctgaaga gacagaaacc agccccagag gtgtcacagg aagkcaccag    300
caaaggacat tggtcttgat tgattcagca gtcctgtyca rtataaatgt gatggctgtg    360
ctgcctggnc ctctgnag                                                  378

<210> 574
<211> 929
<212> DNA
<213> Homo sapiens

<400> 574
tttatataca aacgtacata caaagtttgg atttttattg aaatcttgtt aggtatcaaa     60
caaattctgc tttcttcaga taaaaatatt ctctcagatg tctccagata actgctaagt    120
ctaaattggt ccttcaatgt cttattttta ttgtcctcgt gaaatgttca tatacagtta    180
agatgttccc aaaaggattt ttatcgtgta aaggagcgta catgacgacc tctaccactg    240
cctccactaa caaactttcc tcttgagcct ccactgccgc tatttgcact agcccaggaa    300
ggtccaagtc ccccacgacc tctagaagca cggtcccgag gacttgggcg gtaacctgta    360
gaactaaggg gtcgtaatgg tggaagaggg cctctgttaa aattgctctg gcctccacga    420
ctttcattgt aatttcctcg aggagtattc tgagcactcc aactggagcc tcttgttcct    480
tcccgacgac tgtagtttcc ttttgaagca ggtggtgtga aaaacctatt ctgactgtgg    540
aaagcacccc gtcctcctct attgcctgaa aacccaccac gggaagaaat cttctgtgat    600
actttgagtg gccgttttgg tggaggtatt ccatcttgag gaatagtact ccattagagt    660
aataagactt tggagatttt tctccagact aaaaacatgg ccaacagctg atcttcccac    720
aggattaraa gtaatcaaat aaagattgtg cagggttccc aagagatctg aatggtctgt    780
ttcttcactg gctgtacaac gctgaaaatg gctgaacagt tctgtaatac attgcaatgt    840
ctgtgttgag tcctgtagcc acaaggcaaa tgcatcatca ataacaccca tcagatggag    900
accttcctcc tcatcttgat cataaaagt                                      929

<210> 575
<211> 2360
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1733)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2328)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2340)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2343)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2350)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2355)
<223> n equals a,t,g, or c

<400> 575
ggatgatcga cgaacagtag acagtattcc tgaggaggaa gaggaagatg aagaggaaga     60
aggtgaagag gatgaagaag gggatgatgg ttatgaacaa atttccagtg atgaagatgg    120
aattgctgac ttggaacgtg aaacatttaa gtatccrrac tttgatgttg aatacactgc    180
tgaagactta gcttcagttc ctcctatgac atatgatcca tatgacaggg agcttgtacc    240
actcttatac ttcagttgtc catacaagac tacttttgaa attgaaatca gtagaatgaa    300
ggatcaaggt ccagataaag aaaattcagg ggcaatcgaa gcctcagtga agttaacaga    360
actcttagat ttgtatagag aagatagagg tgcaaaatgg gtaacagctt tagaagaaat    420
tccaagttta ataataaaag ggttaagcta tttgcaattg aaaaacacaa aacaagactc    480
ccttggccag ttggtagact ggaccatgca agctttaaat ttacaagtag cgcttcgcca    540
acctatcgcc ttaaatgttc gacagctcaa agctgggacc aaattagtgt cctcactagc    600
agaatgtggg gctcaaggag ttacaggact gctacaagca ggagtgatca gtggattatt    660
tgaacttctg tttgctgatc acgtatcatc ttctcttaag ttaaatgctt ttaaagcttt    720
ggacagtgtc attagtatga cagaaggaat ggaagctttt tttaagaggt aggcagaatg    780
aaaaaagtgg ttatcaaaag cttctggaac tcatactttt agatcagact gtgagggttg    840
ttactgctgg ttcagctatt ctccaaaaat gccatttcta tgaagtcttg tcagagatta    900
aaagacttgg tgaccattta gcagagaaga cttcatctct tcctaaccac agtgaacctg    960
atcacgacac agatgctgga cttgagagaa caaacccaga atatgaaaat gaggtggaag   1020
cttctatgga tatggatctt ttggaatcct caaatataag tgaaggggaa atagaaaggc   1080
ttattaacct cctagaagaa gtttttcatt taatggaaac tgcccctcat acaatgatcc   1140
aacaacctgt taagtctttc ccaacgatgg cacgaattac tggacctcca gagagggatg   1200
atccataccc tgttctcttt agatatcttc acagtcatca cttcttggag ttggttacct   1260
tgcttctgtc aattccagta acaagtgctc accctggtgt gctgcaagcc acaaaagatg   1320
ttttgaagtt tcttgcacag tcacagaagg gtcttctttt ttttatgtcg gaatatgaag   1380
caacaaattt attgatccga gctctgtgtc acttttatga tcaagatgag gaggaaggtc   1440
tccaatctga tggtgttatt gatgatgcat ttgccttgtg gctacaggac tcaacacaga   1500
cattgcagtg tattacagaa ctgttcagcc attttcagcg ttgtacagcc agtgaagaaa   1560
cagaccattc agatctcttg ggaaccctgc acaatcttta tttgattact tttaatcctg   1620
tgggaagatc arctgktggc catgttttta gtctggagaa aaatctccaa agtcttatta   1680
ctctaatgga gtactattcc aaagaagcct tgggtgattc caaatctaag aantcagtag   1740
cttataatta cgcatgcata cttattttgg tggtggttca gtcttccagt gatgttcaaa   1800
tgctagaaca acatgcagca tctctcttga agctttgtaa agcagatgaa aataatgcta   1860
aattgcaaga acttggcaag tggcttgaac ctctgaaaaa ccttagattt gaaattaact   1920
gcatcccaaa cttaattgag tatgttaagc agaatatcga taacttgatg accccagaag   1980
gagttggcct taccactgcc ttacgtgttc tctgtaatgt tgcatgccca ccacctcctg   2040
ttgaaggtca acagaaagat ctgaaatgga atcttgccgt tattcagctt ttttctgctg   2100
aaggaatgga cacgtttatt cgagttctgc aaaaattgaa cagtattctg actcagcctt   2160
ggaggctcca tgtcaacatg gggactaccc ttcacagagt tactactatt tcaatggctc   2220
gctgcacact cactcttctt aaaactatgt taacggaact cctgagaggt ggatcctttt   2280
gagtttaagg acatgcgtag tccttcagcg cttggtcttt catatgcnct gcgctctatn   2340
ccncttcatn gtccntttgg                                               2360

<210> 576
<211> 1213
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1157)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1169)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1201)
<223> n equals a,t,g, or c

<400> 576
accttcccgg gtcgacccac gcgtccgagg cggcagcggt tggaggcttc gcccggcttt     60
gcagcgggga cttcggcggc ggcgcctcag gcacctcggc ccggacacga tgaggcgagt    120
ggtacgacag agcaagtttc ggcatgtatt tgggcaagcg gtgaaaaatg accagtgcta    180
tgatgacatc cgggtttctc gtgtgacctg ggatagttcc ttttgtgctg tcaatcccag    240
atttgttgcc ataatcatag aggcaagtgg gggaggagcg ttccttgtcc tccctctgca    300
caagactggt cgaattgaca aatcttaccc tacagtatgt ggccacacag gaccagtgct    360
ggacatagac tggtgcccac ataacgatca ggtcattgcc agcggttcag aggactgcac    420
ggtcatggta tggcagatcc cagaaaatgg actcaccctt tccctgactg aacctgtggt    480
gattttggaa ggccactcaa agagagtcgg catcgtggct tggcatccaa cggcccgcaa    540
tgtgcttctt agtgcaggct gtgataatgc cattatcatc tggaatgtgg gaacagggga    600
agcccttata aacttggacg atatgcattc agacatgatt tacaatgtga gctggaaccg    660
gaatggcagt ctgatctgca cagcttccaa agacaagaaa gtgagagtca ttgatcccag    720
gaaacaagag attgttgctg agaaggagaa agcacatgaa ggagcaagac ccatgagagc    780
catcttcctg gccgatggca atgtcttcac cactgggttc agccgcatga gcgagcggca    840
gctggctctc tggaatccga aaaatatgca ggaaccaatt gctcttcatg agatggacac    900
tagcaatggg gtgttgctgc ctttctatga ccctgacacc agcatcattt acttatgtgg    960
aaagggtgac agcagtattc gctattttga gatcacggat gaatccccgt acgtccacta   1020
cctcaacaca ttcagcagca aggagcctca gagagggatg ggttacatgc ccaagagggg   1080
acttgatgtt aacaaatgtg agattgccag attcttcaaa cttcatgaga gaaagtgtga   1140
acctatttta aattttnaat ggaaccttng ggttttttcc ccccccccca aaaggggggg   1200
naaaaaaaag ggg                                                      1213

<210> 577
<211> 2248
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2178)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2247)
<223> n equals a,t,g, or c

<400> 577
gtgaagaaat acaaggtgat ggccctaaga aggagcgcac caagcttatc acccctcagg     60
tggccaaact ggagcacgcc tataagccag tgcaatttga gggctctttg ggaaagctta    120
ccgtttctag tgtgaataat ccccgaaaaa tgattgatgc tgttgtgaca tctcggagtg    180
aggatgatga gacaaaagaa aaacaagttc gagacaagag gagaaaaacc cttgttataa    240
ttgagaaaac ctacagctta ctccttgatg tggaggacta tgaaagacgt tatctcctaa    300
gtctggaaga agagcgacct gccctaatgg atgacagaaa gcacaaaatt tgtagcatgt    360
atgacaactt aagggggaaa ttgcctggac aagagaggcc tagtgatgac cactttgtac    420
agatcatgtg tatccgaaaa gggaagagaa tggttgcccg tattcttcct ttcctctcca    480
cagagcaagc agctgacatt ctcatgacaa cagccaggaa cctccctttc cttatcaaga    540
aggatgcaca agatgaggtg ctgccatgct tactgagtcc cttctctctc cttctctatc    600
atcttccatc agtgagtatc accagccttt tgcgacagct aatgaaccta cctcaaagtg    660
cagctacacc agcactctcc aatcctcacc tcactgctgt gctccagaac aagtttggcc    720
tgtcactgct cctcatcctc ctgagccgtg gtgaagacct acagagttca gaccctgcta    780
cagaatcaac acaaaataat cagtggacgg aggtgatgtt catggcaaca cgagaacttc    840
tgcggattcc ccaagcagcc ctggccaagc caatctctat acctacaaac ctagtgtccc    900
tcttttctcg ctatgttgac cggcagaaac tgaacttgct ggagacaaaa ctgcagctag    960
ttcaggggat acgataaaag atctccaaat gtgtcctgta cctccttttg gctgccacct   1020
gcactgctgc catcaccaat ggagtgtttt taatgaggga aggaaggtag ctttttcccc   1080
aaagcaaagt cttgtgggat cgattcctgt ttacaggggt tgtctctctw aatktcagat   1140
atttccccac tgctctatga aatttggctg ggtgatactt ctgctggttt ctttaccttc   1200
tgtgttacag ttctgcatgt cctactttta ctcagttctg ttttgcattt tctttgccct   1260
agagacacaa gtgtaatctc tccctttatc cctccactac tccacctcag agtagattgt   1320
agcctgccaa aggattcctt ccctcatcct attgaagttg ttttttcatt gccccatatt   1380
aatatgacta tagaagagcc aattaagtag aaatcaagat atacacacac acatagatac   1440
acacacacac accccataca tgtatttatg tggtcttcag agggtcctta aagaatgaat   1500
tttagattga aaaatattta gttgtctcat tacctcttct aaacacaaac cagctgatgt   1560
attttaatct gtttctgttc tatcttgtaa ttaatttggt gggttctact tgttttaaca   1620
taaataaaga gtatgcagca cgtttaataa aatcagaact cttaattggc ttatgcccag   1680
gtctaggctg agaagtcctt tttcttcttc ccacctttat ttccttagtt tctgtccacc   1740
ttaatcgaaa caacacatgg ttatgtcttt ttcctgctac aactacaggg tacttgagcc   1800
tttcccctca agtgcattcg aagtcaccca ggatgatcct cactagtagc ctgctttggc   1860
agtgtggctt tttgcacact tgccctgtct tcctgagact acttcagtaa gccatgcttc   1920
cttcttcccc acttttattt ggtgtcatga atagaaactt ccaaatgtaa ccatggaagc   1980
taagtttggc ctgctttgct ttttagtctc cacaccatgg gcagaactgc tgtctttact   2040
acttcatctc acccaagtcc cgttcccagg cagccagggg cctgggtttt gaataattgc   2100
agggccagcc tgccatgatc tttctcamtt actcctctcc cattcagcaa tcaaccagac   2160
taaggagttt tgatcccnag gattamagcc ctgaagaaaa ttaaatctga attaatttta   2220
catggccttc gtgatctttc tgctgtnc                                      2248

<210> 578
<211> 1031
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (307)
<223> n equals a,t,g, or c

<400> 578
gtacgcctgc aggtaccggt ccggaattcg cggccgcgtc gacggctgag cacctttttt     60
attaataggt ataataaata aataaataaa tacataaaca gacgcctggg ctcctcctcc    120
ctcttctgat gaccaggcac tggccacagc ctatttacag ctggggggct tagggatctg    180
gccccaatac tgttacccat cctcatctcc acctggccta gggaaccctg tagatggctt    240
tctgggccac ccgcctccag ggggacttgc ttgtcttcac ccatggaagg gttggcccar    300
acgggcnagg ggaatcctgg cagcccagtg ctgtgtccca tccctctcct gggtggaggt    360
ctggacaagg tcactgggac agttaagggg gcgtaattaa tactgagcac agggagcagg    420
tgccagcaca gggatacgtg gccccagctc tcagtctact ctgcagccaa gccaatggct    480
tgggaagggc tctcgggctc tgagtctggg ggttatgagg gtccctgagg ccaccagcat    540
gcacagggcc tcagttttgg ctgcttccag gggttggact tggagttggg gtcaatgtca    600
cgtagccagg gcaccaggcc agagtcgggg ccacgtgcag gcagccagtc tcctccagct    660
cgccccagca ctcgtaggat gtctcctttg tggaagctca gctgtccagg ccggtggcca    720
ggtggtggca cagtgcctgc acctcacacg gaggactgga gggcagggct ggggagtgtg    780
gctcctgcag gctctccttg ggctctggct ccggcgggaa cccactgtct gcgccactag    840
ttggaacatg gacttgtcca ggctcagcca gtccgagggg agcctatttg tgggccgggc    900
ctcccgctgg gcttttcggg agccaaagag ktgtccccac ttgatgcctc caggtgaagg    960
ctctgaggcc ccttcctcat ttactgctgg cgaggcagcg ggcccttccc tctcccgact   1020
gcgcctcagc t                                                        1031

<210> 579
<211> 793
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (237)
<223> n equals a,t,g, or c

<400> 579
ctcctagtga acttggttga tgtgaaggag ggtacacagg ttttatgctc tgggcaattt     60
cacagcagtg cacagtagct cctctgtccc tcgtgcatgt gcttctgctt gtcttcagca    120
tgttacaaag atggacccga gttgcaatgg ttcccatcgc tgttctaatg tctccaggta    180
tatctttctt catacttctc cagcataggg gaagctttag ttcaagcatt tcttttnttt    240
tttttccaaa tgcagaaaaa aagtctttat tctcataata aaaataagtc tgttctgtat    300
tttacaatat atttcaaata tttccactat gaagcattca ttagtcccac atggtcaaga    360
agtatacaac cttttccaaa gacagagctg ccgggagtgt gtttaggaca cacacctcgt    420
acagccgcac ttcaccactt tctcaacctc gtccacaaag gaggagccgt cagtgcattc    480
gaaagagtat ttccgccgct tgctcctcag cggtccacag cactgccctc ctgcacaccc    540
acctctgcac tctaatcggg acaccttctt ggttgtttgg gcaagcaggc atagccctgc    600
tgcttttggt aataatctct tatcctttcc cctcgacaag agatttctcg atcacagctg    660
tcccccgtgt atccatgctg cattcacagt agggctgccc cagacctgaa agcctgcact    720
tccccatgct tgcacttgat cgcctggcat gggttaaaca gatcctcctc ttcatgcaca    780
gaggacacct aca                                                       793

<210> 580
<211> 1906
<212> DNA
<213> Homo sapiens

<400> 580
gctcgccagg cgccacgaag ccccggcgtc ccacaggtcc cggaggccgc tgcgtcgcgg     60
ggagctgggc tcgggccgcc ggcggttgcg ccggggcagc cccgcgggga gagcaccatg    120
aggactgact cgggggctcg gctggaggag ggccacctgc gtcctccacg agctcttcca    180
cctgtgccaa gtcaagatga tattccactt agtcgtccta agaaaaagaa gcccagaaca    240
aaaaacacac cagcaagtgc ttctttggaa ggccttgctc agactgctgg tcgaaggccc    300
tctgagggma atgagccatc aactaaagaa ctcaaagagc acccagaggc tcctgttcaa    360
agaagacaga aaaagacaag gctacctctt gaattggaga cttcctccac ccaaaagaag    420
tcatctagtt catctttatt acgaaatgaa aatggtattg atgcggagcc agctgaggag    480
gcagttattc aaaaacctcg gaggaagaca aagaaaaccc agccagcaga attacagtwt    540
gccaatgagc taggagtagr agrtgaagac atawtcactg atgagcaaac tactgtggaa    600
cagcagtctg tattcactgc acccactggc attagccagc ctgtaggcaa agtatttgtg    660
gaaaaaagcc ggagattcca ggctgctgat cgttcagagt tgataaagac cacagaaaac    720
atagatgtgt caatggacgt gaagccttcc tggaccacca gagatgtggc acttacagtg    780
caccgggctt tcaggatgat tggtctcttt tctcatggat tcttggctgg ctgtgctgtg    840
tggaatattg ttgtgatata tgttctagca ggagatcagc tatccaacct ctcaaacctt    900
ctgcaacaat acaagaccct agcgtatcca ttccagagtc ttctgtactt gcttttggct    960
ctgagtacaa tttcagcttt tgacaggatt gactttgcta aaatatcagt agcaatccga   1020
aattttttgg ccctggatcc tacagcttta gcatctttct tgtactttac tgctcttata   1080
ctatctctga gtcagcaaat gacaagtgac agaatccacc tttacacacc ttcttctgtt   1140
aatggtagcc tctgggaagc aggaattgag gaacagattc tccagccatg gattgtggtg   1200
aatctcgtgg tggctcttct ggttggatta tcttggctat ttttgtctta taggccaggc   1260
atggatctta gtgaagagtt aatgttctcc tcagaggtgg aagaatatcc tgataaagag   1320
aaagaaatca aagcctcttc ataataccag ctcacctttg gaggaataat gacccagtat   1380
ttgtcccatt tttgttttta aatgtatttt tataagatgt atacatgtgt atttgtaata   1440
gattttttga ttatataata ctgaaacatc tctcaatatt atgaaaaatg ttaaaattgt   1500
gtttgctgtt tatgtctaaa cattaatttg tctagcatta tcatcttaat gacaaaggga   1560
ataatgaact agaaaccagc aagtgaaagt gtttatttcc tattttctca aaacagttgt   1620
atttataact attaccttaa aaagcactgg tttagaaaaa gccataactt aaatagtgtt   1680
ataaaatata tatcaggttt aaacataaat ttagcgaata tggtagaagg gaaaaaagcc   1740
ttcatttttg acctcccctt actgaataaa ttgaaatatg aagtttgtct tttctgaaac   1800
tggcttagtg attgagtatc atgtaataat tataatataa tttagcttga aagatgctct   1860
acattatgac caataaaaag ggaatgtatg ttttgtttga aaaatt                  1906

<210> 581
<211> 1378
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1353)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1364)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1367)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1376)
<223> n equals a,t,g, or c

<400> 581
ggcacagctg ggctggccga agggttggcg ctgcgatccc gcasggcagc gacgcgactc     60
tggtgcgggc cgtcttcttc cccccgagct gggcgtgcgc ggccgcaatg aactgggagc    120
tgctgctgtg gctgctggtg ctgtgcgcgc tgctcctgct cttggtgcag ctgctgcgct    180
tcctgagggc tgacggcgac ctgacgctac tatgggccga gtggcaggga cgacgcccag    240
aatgggagct gactgatatg gtggtgtggg tgactggagc ctcgagtgga attggtgagg    300
agctggctta ccagttgtct aaactaggag tttctcttgt gctgtcagcc agaagagtgc    360
atgagctgga aagggtgaaa agaagatgcc tagagaatgg caatttaaaa gaaaaagata    420
tacttgtttt gccccttgac ctgaccgaca ctggttccca tgaagcggct accaaagctg    480
ttctccagga gtttggtaga atcgacattc tggtcaacaa tggtggaatg tcccagcgtt    540
ctctgtgcat ggataccagc ttggatgtct acagaaagct aatagagctt aactacttag    600
ggacggtgtc cttgacaaaa tgtgttctgc ctcacatgat cgagaggaag caaggaaaga    660
ttgttactgt gaatagcatc ctgggtatca tatctgtacc tctttccatt ggatactgtg    720
ctagcaagca tgctctccgg ggttttttta atggccttcg aacagaactt gccacatacc    780
caggtataat agtttctaac atttgcccag gacctgtgca atcaaatatt gtggagaatt    840
ccctagctgg agaagtcaca aagactatag gcaataatgg agaccagtcc cacaagatga    900
caaccagtcg ttgtgtgcgg ctgatgttaa tcagcatggc caatgatttg aaagaagttt    960
ggatctcaga acaacctttc ttgttagtaa catatttgtg gcaatacatg ccaacctggg   1020
cctggtggat aaccaacaag atggggaaga aaaggattga gaactttaag agtggtgtgg   1080
atgcagactc ttcttatttt aaaatcttta agacaaaaca tgactgaaaa gagcayctgt   1140
acttttcaag ccactggagg garaaatgga aaacatgaaa acagcaatct tcttatgctt   1200
ctgaataatc aaagactaat ttgtgrtttt actttttaat agatatgact ttgcttccaa   1260
catggaatga aataaaaaat aaataataaa agattgccat gaatcttgca aaaaaaaaaa   1320
aaaaaaaatt caaggggggg cccgggtccc atnccccctt tggngantcc ttttanaa     1378

<210> 582
<211> 772
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (56)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (771)
<223> n equals a,t,g, or c

<400> 582
ccgaacgccc agaaaaaagn taaccaggta accgccgaaa atagaatcgc ccccancagt     60
ttcccctggc tgccaaatat gaccaattcc cgctgcttct atcgccagta ctttcgtcgt    120
tactgccggg atgttcggcg caatgagcct gtacggttac accacgaagc gcgatttaag    180
tggctttggc aatatgctgt ttatggcgtt aatcggcatt gtgctggcat cgctggtcaa    240
cttctggttg aaaagcgaag cattgatgtg ggcagttacc tacatcggcg tgattgtctt    300
tgtcggattg acggcgtatg acacgcagaa actgaaaaat atgggtgagc agattgatac    360
ccgcgacacg tcgaacctgc gcaaatattc cattcttggc gcgttaacct tgtatctgga    420
cttcatcaac ctgttcctga tgttgttgcg gatcttcggc aaccgccgcg aatctgaaga    480
gcgtcaacct ggtcgctaac ttcaataccc tgtttgtact ggtgcaaatc tccatcatgg    540
tggtgtttat cttcctggta gttcagggac tgcataaagg agaaggcgtt ggcaccgtct    600
ggtcacttca gccgtttatc agcgagaacg cgcacctgat cccgattatt accggggcga    660
cgattgtctg tttctccttc ctcggtttcg atgcggtgac cacgctttcg raagagacgc    720
cggacgccgc acgcgtgatc ccgaaagcca tcttcctgac gggggggccc na            772

<210> 583
<211> 1787
<212> DNA
<213> Homo sapiens

<400> 583
gcccagatcc atctcctagg aaggaccgtc atgacacccc ggatccatct cctaggaggg     60
cccgtcatga caccccggat ccttctcccc tcagaggggc tcgtcatgac tcagacacat    120
ctcctcccag gaggatccgt catgactcct cagacacttc acccccaagg agggcccgtc    180
atgattctcc agatccttct cccccaagga ggcctcagca taattcttca ggtgcatctc    240
ctaggagagt ccgtcatgat tcaccagatc cctctcctcc taggcgagcc cgtcatggtt    300
cctcagatat ctcttccccc agaagggtcc ataacaactc ccctgacaca tctrggagga    360
ctcttggctc ttcagacaca cagcaactca gaagggcccg tcatgactcc cctgatttgg    420
ctcctaatgt cacttattcc ctgcccagaa ccaaaagtgg taaagcccca gaaagagcct    480
ctagcaagac ttctccacat tggaaggagt caggagcctc ccatttgtca ttcccaaaga    540
acagcaaata tgagtatgac cctgacatct ctcctccacg aaaaaagcaa gcaaaatccc    600
attttggaga caagaagcag cttgattcca aaggtgactg ccagaaagca actgattcag    660
acctttcttc tccacggcat awacaaagtc cagggcacca ggattctgat tcagatctgt    720
cacctccacg gaatagacct agacaccgga gctctgattc tgacctctct ccaccaagga    780
ggagacagag gaccaaatct tctgattctg acctgtcccc gcctcgaagg agtcagcctc    840
ctggaaagaa gctgcacaca tgtattctgg ggctaaaact gggttggtgt taactgacat    900
acagcgagaa cagcaggagc tcaaggaaca ggwtcaagaa accatggcat ttgaagctga    960
atttcaatat gctgaaaccg tatttcgaga taagtctggt cgtaagagga atttgaaact   1020
cgaacgttta gagcaaagga ggaaagcaga aaaggactca gagagagatg agctgtatgc   1080
ccagtgggga aaagggcttg cccagagccg gcaacagcaa caaaatgtgg aggatgcaat   1140
gaaagagatg caaaagcctc tggcccgcta tattgatgac gaagatctgg ataggatgct   1200
aagagaacag gaaagagagg gggaccctat ggccaacttc atcaagaaga ataaggccaa   1260
ggagaacaag aataaaaaag tgagacctcg ctacagtggt ccagcacctc ctcccaacag   1320
atttaatatc tggcctggat atcgctggga cggagtggac agatccaatg gatttgaaca   1380
gaagcgcttt gccaggcttg ccagcaagaa ggcagtggag gaacttgcct acaaatggag   1440
tgttgaggat atgtaacttt cctgaggctg tgggggtggc tgggctgtgg tagtgggcat   1500
aggcagcgag atatccagtg gtaacagttg tctgtgctaa taattggagc ccacacagac   1560
cagcaacttg ttgaatgcca sttttgacca cagaagaata ttcgagacct gatgtttgga   1620
ctgaggtacc tgtacttctt gggtgtgaca gcaccggctg ttgctggctt tcagaggaag   1680
cattgatttc tcattgacca gggtttgttc ttggtagggt ttttcttttt cttttttaaa   1740
taaacatgta tttatttttt taaaaaaaaa aaaaaaaaaa aamtcga                 1787

<210> 584
<211> 1125
<212> DNA
<213> Homo sapiens

<400> 584
ttttttttgc acttcgccca cacaggacag tggagcccca cctggtcagt tccacttccg     60
ggctcccatg cacttgccca aggcggcctc tttgggacgg ggatggtttg aggaaacact    120
tttaaagaaa aaaggaagac attgaaaggt tttagtttct tccctatctg catgtcctct    180
catatagaaa gcccagaatt aggggctaga actccaggag agggtctccc cgactcatct    240
cttgctgacg gtcaccagga tgcagaaata gggagatggt tagtgggggc caaagatgcc    300
ccctcccagg ccttcgtggt tccctcctcc gccccctgca atctttggag gagtcagtgc    360
ctcactccag cagtgagtgc ctactgtatg caggtagtca gccaggcaaa gagagactaa    420
cggtctcatg ggggaaccct cttgcgggag gccaggtagc tggagcgaag cgttccggct    480
gcccttgctg ctgggtggag tggagaggga gacttctttt tgttggtttt aatttaaaaa    540
cacaaaggcc taaagaaata cgtatcttat aattttttta atttttgaga cgttcattta    600
atgaattgtg cacgaatgaa ttctatatat ataaaatata catatatagc tctatatttg    660
gggaggggca ctgtctcttt tttctctcat ttttaaaatg aagtgttgtt gcctttgtat    720
gtggttcaac catccagctc ccagctggct aaactttgcc tccagtggtc aaagatggga    780
aaagagtggg gttggcagga gatggaaaac ggaggtgccg ccccagcatg gggggcaggt    840
cccccagtcc accctgcccc tccccctgtg gagaagacgc ttagttgggg gtgtgggttt    900
gggctccatt ctggattcgg cggttccggg ggaggggtgg gtctgtgccg attactctgt    960
cttgtacgtt tgttctgctg ctcttcaata ttgtatcaac gccaggaaag gggggtgaaa   1020
agcctctttt accccccaaa taaattgtca cattccgaag ctgaaaaaaa aaaaaaaaaa   1080
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagggg ggggc                   1125

<210> 585
<211> 2043
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2035)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2037)
<223> n equals a,t,g, or c

<400> 585
gggggagcgc gcgcgccgcc gccgttgccg ccgggctgag agaagagctt gcggggtttg     60
cggttgatgg ccccgactga agggctggag gcggtgtatg ccgctgttct tgctgtcgct    120
cccgacacct ccgtccgctt ctggtcatga gaggagacag aggcctgaag caaagacatc    180
tgggtcagag aaaaagtatt taagggccat gcaagccaat cgtagccaac tgcacagtcc    240
tccaggaact ggaagcagtg aggatgcctc aacccctcag tgtgtccaca caagattgac    300
aggagagggt tcttgccctc attctggaga tgttcatatc cagataaact ccatacctaa    360
agaatgtgca gaaaatgcaa gctccagaaa tataaggtca ggtgtccata gctgtgccca    420
tggatgtgta cacagtcgct tacggggtca ctcccacagt gaagcaaggc tgactgatga    480
tactgccgca gaatctggag atcatggtag tagctccttc tcagaattcc gctatctctt    540
caagtggctg caaaaaagtc ttccatatat tttgattctg agcgtcaaac ttgttatgca    600
gcatataaca ggaatttctc ttggaattgg gctgctaaca acttttatgt atgcaaacaa    660
aagcattgta aatcaggttt ttctaagaga aaggtcctca aagattcagt gtgcttggtt    720
actggtattc ttagcaggat cttctgttct tttatattac acctttcatt ctcagtcact    780
ttattacagc ttaatttttt taaatcctac tttggaccat ttgagcttct gggaagtatt    840
tkggattgtt ggaattacag acttcattct gaaattcttt ttcatgggct tawaatgcct    900
tattttattg gtgccttctt tcatcatgcc ttttaaatct aagggttact ggtatatgct    960
tttagaagaa ttgtgtcaat actaccgaac ttttgttccc ataccagttt ggtttcgcta   1020
ccttataagc tatggggagt ttggtaacgt aactagatgg agtcttggga tactgctggc   1080
tttactctac ctcatattaa aacttttgga attttttggg catctgagaa ctttcagaca   1140
ggttttacga atatttttta cacaaccaag ttatggagtg gctgccagca agagacagtg   1200
ttcagatgtg gatgatattt gttcaatatg tcaagctgaa tttcagaagc caattcttct   1260
catytgtcag catatatttt gtgaagagtg catgacctta tggtttaaca gagagaaaac   1320
atgtccactc tgcagaactg tgatttcaga ccatataaac aaatggaagg atggagccac   1380
ttcatcacac cttcaaatat attaagttgt ataaactatc aaggccacaa aatactaatg   1440
tcatttggtc ataatgacta ctgataaggc atcagaatgg attttcaggg ctaccagaaa   1500
aatgtttcca gatggtttta gaatgtagga cttatgatcc aattcaccaa aagattaaat   1560
gaaaccaccc tgtgttttaa aatatatata atgttcaacc taatgtatat gcaacattta   1620
ttctattcta attatttgac aggtaactgc agtgttaaat tgtaaatgtg ttttctttat   1680
gttaccaaaa cagcaatttg aaattagaac tagtggtttt agagaactca ggtattcttt   1740
cctgacattg ttttcagaat aaagaatatt tttcataata ttttaagata catactatct   1800
aaaagtagaa ttttgttcag cattgacttt tataattccc atcctaaaaa ttcttaatat   1860
tttcataaaa tttgtatttt taaatgaaaa ttctaaatgt tgtattttat cagtaacatt   1920
ttctaagtga agattaattt actgaggatg atacattata gtattgtatt attctctgta   1980
gtaagattag taataagtga aaataaatga tttaaattca aaaaaaaaaw aaaantnact   2040
cga                                                                 2043

<210> 586
<211> 2898
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2893)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2897)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2898)
<223> n equals a,t,g, or c

<400> 586
cattcttccc cctcaaaggg cgccaaatct gtacatggtc ccccagggga tcaggcctgt     60
ggtccagctc actgccattg agattctagc ttggggctta agaaatatga aaaacttcca    120
gatggcttct atcacatccc ccagtcttgt tgtggagtgt ggaggagaaa gggtggaatc    180
ggtggtgatc aaaaacctta agaagacacc caactttcca agttctgttc tcttcatgaa    240
agtgttcttg cccaaggagg aattgtacat gcccccactg gtgatcaagg tcatcgacca    300
caggcagttt gggcggaagc ctgtcgtcgg ccagtgcacc atcgagcgcc tggaccgctt    360
tcgctgtgac ccttatgcag ggaaagagga catcgtccca cagctcaaag cctcccttct    420
gtctgcccca ccatgccggg acatcgttat cgaaatggaa gacaccaaac cattactggc    480
ttctaagctg acagaaaagg aggaagaaat cgtggactgg tggagtaaat tttatgcttc    540
ctcaggggaa catgaaaaat gcggacagta tattcagaaa ggctattcca agctcaagat    600
atataattgt gaactagaaa atgtagcaga atttgagggc ctgacagact tctcagatac    660
gttcaagttg taccgaggca agtcggatga aaatgaagat ccttctgtgg ttggagagtt    720
taagggctcc tttcggatct accctctgcc ggatgacccc agcgtgccag cccctcccag    780
acagtttcgg gaattacctg acagcgtccc acaggaatgc acggttagga tttacattgt    840
tcgaggctta gagctccagc cccaggacaa caatggcctg tgtgaccctt acataaaaat    900
aacactgggc aaaaaagtca ttgaagaccg agatcactac attcccaaca ctctcaaccc    960
agtctttggc aggatgtacg aactgagctg ctacttacct caagaaaaag acctgaaaat   1020
ttctgtctat gattatgaca cctttacccg ggatgaaaaa gtaggagaaa caattattga   1080
tctggaaaac cgattccttt cccgctttgg gtcccactgc ggcataccag aggagtactg   1140
tgtttctgga gtcaatacct ggcgagatca actgagacca acacagctgc ttcaaaatgt   1200
cgccagattc aaaggcttcc cacaacccat cctttccgaa gatgggagta gaatcagata   1260
tggaggacga gactacagct tggatgaatt tgaagccaac aaaatcctgc accagcacct   1320
cggggcccct gaagagcggc ttgctcttca catcctcagg actcaggggc tggtccctga   1380
gcacgtggaa acaaggactt tgcacagcac cttccagccc aacatttccc agggaaaact   1440
tcagatgtgg gtggatgttt tccccaagag tttggggcca ccaggccctc ctttcaacat   1500
cacaccccgg aaagccaaga aatactacct gcgtgtgatc atctggaaca ccaaggacgt   1560
tatcttggac gagaaaagca tcacaggaga ggaaatgagt gacatctacg tcaaaggctg   1620
gattcctggc aatgaagaaa acaaacagaa aacagatgtc cattacagat ctttggatgg   1680
tgaagggaat tttaactggc gatttgtttt cccgtttgac taccttccag ccgaacaact   1740
ctgtatcgtt gcgaaaaaag agcatttctg gagtattgac caaacggaat ttcgaatccc   1800
acccaggctg atcattcaga tatgggacaa tgacaagttt tctctggatg actacttggg   1860
tttcctagaa cttgacttgc gtcacacgat cattcctgca aaatcaccag agaaatgcag   1920
gttggacatg attccggacc tcaaagccat gaaccccctt aaagccaaga cagcctccct   1980
ctttgagcag aagtccatga aaggatggtg gccatgctac gcagagaaag atggcgcccg   2040
cgtaatggct gggaaagtgg agatgacatt ggaaatcctc aacgagaagg aggccgacga   2100
gaggccagcc gggaaggggc gggacgaacc caacatgaac cccaagctgg acttaccaaa   2160
tcgaccagaa acctccttcc tctggttcac caacccatgc aagaccatga agttcatcgt   2220
gtggcgccgc tttaagtggg tcatcatcgg cttgctgttc ctgcttatcc tgctgctctt   2280
cgtggccgtg ctcctctact ctttgccgaa ctatttgtca atgaagattg taaagccaaa   2340
tgtgtaacaa aggcaaaggc ttcatttcaa gagtcatcca gcaatgagag aatcctgcct   2400
ctgtagacca acatccagtg tgattttgtg tctgagacca caccccagta gcaggttacg   2460
ccatgtcacc gagccccatt gattcccaga gggtcttagt cctggaaagt caggccaaca   2520
agcaacgttt gcatcatgtt atctcttaag tattaaaagt tttattttct aaagtttaaa   2580
tcatgttttt caaaatattt ttcaaggtgg ctggttccat ttaaaaatca tctttttata   2640
tgtgtcttcg gttctagact tcagcttttg gaaattgcta aatagaattc aaaaatctct   2700
gcatcctgag gtgatatact tcatatttgt aatcaactga aagagctgtg cattataaaa   2760
tcagttagaa tagttagaac aattcttatt tatgcccaca accattgcta tattttgtat   2820
ggatgtcata aaagtctatt taacctctgt aatgaaacta aataaaaatg tttcaccttt   2880
aaaaaaaaaa canactnn                                                 2898

<210> 587
<211> 2209
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> n equals a,t,g, or c

<400> 587
gcgcaaatgc ttgtgccaag caatatgcgg gaactggngc cttgaagact gactttacca     60
gaactggaaa gagaactcat ttgggactta taatggatgg ctggaactca atgatacgat    120
attataagaa caacttttcc gatggattta gacaagattc catagactta tttcttggaa    180
actattcagt ggatgaatta gaatctcata gtcctttaag tgttccaagg gactggaaat    240
tcctggcttt gcctattatc atggttgttg ccttttcaat gtgcattatc tgtttgctta    300
tggctggtga cacttggaca gaaacactgg cctatgtgct cttctgggga gttgcaagca    360
ttggaacatt ttttatcatt ctttacaatg gcaaagattt tgtcgatgct cccagactgg    420
tccagaaaga aaagatagac tgaatttgta tttgtggaaa gcggcttggc ttggaagatt    480
ccattgtgca gaactggagt ctttactgac ccgctttcca catcagccca aggtcttttt    540
aatgccttta tccaaaagca catcttgtgc tccatgcagg atgatgacag aattgatctg    600
atgttactgc cttgatggtc tctttactat tgggacagtt agatttataa tttgaagcta    660
ttctgtaatt aaaatataac ctgaattcag cttgcagaat ggaagctgaa tctgttcatt    720
gtattctatt gattgtcaat ttaattagct gttgcagaat aagtaatata ttttaaaaac    780
ctagctcctt tcattattta aaacagcaaa attatttttg tagctcagtt tcattattgt    840
cattgtagaa gcggtcacta ttagcaggca tacttttcca cacatctttg gacttttctt    900
aaaagttcag taataagcta actgtgttta taaaatgtaa gtctcttaca gacatcaagt    960
agtttgatga gacagtctgt gacttcatga taggaaagag gaggatgagg tctggggttc   1020
tttaaagtct ctggtgggct gcctcatgac tttaatcagc ttgaactgcc agtgcaccag   1080
cagtttaggt gtgatgagag aattcagata tactttatct ttttaaaaaa gtgtaaataa   1140
aatcaaagaa tgtaaagtct atctcttacg ctagaggtcc aaagctgcct ctgttttaaa   1200
gattatccca atgtggaaga tgcccatgac tggtcagcta cttcctccta tacattttgg   1260
tttctttgag ggtcactcat tgagacacgc aggcctctga gagggtcttg ttctagattt   1320
catattgcac ttggagggta acagctgctt tttcacgcat ggtactcttg atgtttttca   1380
ctctgtcaag gattttgttg gctatcaatg aatgtgtcta aaacttagtg cttccaggta   1440
gttatagtac tccaaatcaa ggaccaactt aaacgttaat ttttgtgcaa aaacaaacct   1500
gaaaaatatg cttcggaaac tgtgcatagt tctaattgta agtcagattg tatattcaaa   1560
ttgtaattaa gagatttaaa tattagaacg gtatgtaagg tagtataatt accactattt   1620
taaaacaatt cagttaaaca ctgctgcaat atttcagtgt tgtgcttgaa aatatgtaca   1680
gtttttttcc aatattaata ccttatgttg tccttaaata tttctaaaag cgcctttatt   1740
tcagcattac ctttttttca tcactatctt ttataaaaca ttaatataag tcgttacttt   1800
tagaaactaa aggaaataat agctggaaaa ccctctgtag tttaaaatca gtcattaaac   1860
tcacaatagg gtaagtaaat atagccacct gttaacatgt aaataagcat aatttgttcc   1920
aaagatggaa tattgaaact tagttcatgt ctgctgtaaa atattattta aatgctgctg   1980
ggcatttcac ttaaagaact taatgtcaac agctacaaca aagaccaaat ctgaactgct   2040
aatgtggctg ctttgtaggg aatggactaa tatcagtgtg ttagatctta aggtatcagt   2100
atttcagaat cctgcgacga ttttatttct aaattcatgt actgtatgtc cataagtgaa   2160
aataaaatgt catattcttt tcwaaaaaaa aaaaaaaaaa aaaaattac               2209

<210> 588
<211> 320
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (304)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (309)
<223> n equals a,t,g, or c

<400> 588
cccagggcat tgatgattcc aganaaagac aaccggggca cccaagatgc cctgaaccct     60
gaggatgagg tggatgagtt cctgagccgt gccatcgatg cccgcagcat tgatcagctg    120
cggaaggacc atgtgcgccg gtttctgctc accttccaga gagaggatct tgagaagaag    180
tactcccgga aggtggatcc ccgcttcgga gcctacgttg cctgtgccct gttggtcttc    240
tgcttcatct gcttcatcca gcttctcatc ttcccacact ccaccctgat gcttggggat    300
ctangccanc aatcttcctg                                                320

<210> 589
<211> 2078
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2073)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2074)
<223> n equals a,t,g, or c

<400> 589
cccacgcgtc cggtaccgac ccggcagaag ctcggagctc tcggggtatc gaggaggcag     60
gcccgcgggc gcacgggcga gcgggccggg agccggagcg gcggaggagc cggcagcagc    120
ggcgcggcgg gctccaggcg aggcggtcga cgctcctgaa aacttgcgcg cgcgctcgcg    180
ccactgcgcc cggagcgatg aagatggtcg cgccctggac gcggttctac tccaacagct    240
gctgcttgtg ctgccatgtc cgcaccggca ccatcctgct cggcgtctgg tatctgatca    300
tcaatgctgt ggtactgttg attttattga gtgccctggc tgatccggat cagtataact    360
tttcaagttc tgaactggga ggtgactttg agttcatgga tgatgccaac atgtgcattg    420
ccattgcgat ttctcttctc atgatcctga tatgtgctat ggctacttac ggagcgtaca    480
agcaacgcgc agcctggatc atcccattct tctgttacca gatctttgac tttgccctga    540
acatgttggt tgcaatcact gtgcttattt atccaaactc cattcaggaa tacatacggc    600
aactgcctcc taattttccc tacagagatg atgtcatgtc agtgaatcct acctgtttgg    660
tccttattat tcttctgttt attagcatta tcttgacttt taagggttac ttgattagct    720
gtgtttggaa ctgctaccga tacatcaatg gtaggaactc ctctgatgtc ctggtttatg    780
ttaccagcaa tgacactacg gtgctgctac ccccgtatga tgatgccact gtgaatggtg    840
ctgccaagga gccaccgcca ccttacgtgt ctgcctaagc cttcaagtgg gcggagctga    900
gggcagcagc ttgactttgc agacatctga gcaatagttc tgttatttca cttttgccat    960
gagcctctct gagcttgttt gttgctgaaa tgctactttt taaaatttag atgttagatt   1020
gaaaactgta gttttcaaca tatgctttgc trgaacactg tgatagatta actgtagaat   1080
tcttcctgta cgattgggga tataaygggc ttcactaacc ttccctaggc attgaaactt   1140
cccccaaatc tgatggacct agaagtctgc ttttgtacct gctgggcccc aaagttgggc   1200
atttttctct ctgttccctc tcttttgaaa atgtaaaata aaaccaaaaa tagacaactt   1260
tttcttcagc cattccagca tagagaacaa aaccttatgg aaacaggaat gtcaattgtg   1320
taatcattgt tctaattagg taaatagaag tccttatgta tgtgttacaa gaatttcccc   1380
cacaacatcc tttatgactg aagttcaatg acagtttgtg tttggtggta aaggattttc   1440
tccatggcct gaattaagac cattagaaag caccaggccg tgggagcagt gaccatctgc   1500
tgactgttct tgtggatctt gtgtccaggg acatggggtg acatgcctcg tatgtgttag   1560
agggtggaat ggatgtgttt ggcgctgcat gggatctggt gcccctcttc tcctggattc   1620
acatccccac ccagggcccg cttttactaa gtgttctgcc ctagattggt tcaaggaggt   1680
catccaactg actttatcaa gtggaattgg gatatatttg atatacttct gcctaacaac   1740
atggaaaagg gttttctttt ccctgcaagc tacatcctac tgctttgaac ttccaagtat   1800
gtctagtcac cttttaaaat gtaaacattt tcagaaaaat gaggattgcc ttccttgtat   1860
gcgcttttta ccttgactac ctgaattgca agggattttt atatattcat atgttacaaa   1920
gtcagcaact ctcctgttgg ttcattattg aatgtgctgt aaattaagtc gtttgcaatt   1980
aaaacaaggt ttgcccacaw aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2040
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aannaaaa                           2078

<210> 590
<211> 1623
<212> DNA
<213> Homo sapiens

<400> 590
tttttttttt tttttttttt ttttttttgc caaagctggc taagggaata tttttattyt     60
tctgagggca gttaaggctt ytgataagga aagagagtct gaacagagca cacacatytg    120
gagctccagg agtgggggat gcagcatcar attccatctt gaatttctgc taaaatactt    180
tgtactcata atggatctca acaaaratct gtatttcatc tgkggctcca tcttccctct    240
gggtcaagta gatgttaagc tggaccttgg cacgcctctt aacatgaaga gatctagcta    300
gacagacaga ctcccccatt tatggaacaa gaattcaatt tattctctat ttataaaaca    360
tttttttaaa gtgccttggg tataaaaatc taaatgtctg cggtgtgatc agtcaggagc    420
acgtaactat cactcttcgc atcctttggt cactgggaga tcctttgggg gctgggaggt    480
ccttctgtcc caggctaaag gaaaagcttc acaagggtaa gagccacaga accctcggca    540
agaaaggccg gtcagggaga atgaatggta cagagaggaa aggaaggaaa gggggtggaa    600
cagaggtaga aggcaaggaa gggatgccgc actggagacc gatggggaca ctctaattgt    660
gcaagaggga ggatcttcct tcttgaatgc tgaacacagc tagtctgaac cttccttgga    720
aagtccagct gtttgcccat gcatagggcc aactctccct gcaaagcagc aaatgtggct    780
tctatcagga aggaaaagta tccatcagtg tgacaagagg tcaccttcga acttgcatga    840
actccttgcg cagccacaaa gagtcctggt agaagtgagg atcgcctagt cttacggctg    900
tccgtttata gaagtagcag tacaacactg ctgctagtct ctggaataca aacagcattt    960
gaagtccatc tgtccatatg aagctgttgg agtttttcca gcgtaagttc atgacccaga   1020
catgaaggga gatgctgagg gcaaagtaca cagctgtcag gatgatggtc cctttgaact   1080
tatggaatag gaggttgacc aggccagcct ggaagacgaa ggtgttgaag aacatgagga   1140
aaatgatgat gatgttgaag aggactgcaa tatcctggat gatgaagagc acaagctgga   1200
tgacaggagt cttttggagc agttctgaga aggaattgac aaagaggtca taggacagca   1260
gcaggaactg cagagagagc accaggctgt agttactggt ctggagcatc ttccttctgt   1320
tttctcgggc ccccaagggc acatcccaca gttcccagaa aaccgctcct ggctgtctcc   1380
ctaccactga gggagaggct tctagttcct ttgaatgaga gctgtttccc ttgctctaag   1440
gcaagcacct ccaaactcca acgtcggttg tcatgcggac atcgtcccgg cttccggaag   1500
ccggctttaa attccggaag taaatggagg aggcgggccc cgtctgcgcc gtgcggcctg   1560
ctagtccccg gctttctctt cccgctctat ggccagtctg gccgccatgt tggagctttc   1620
gcc                                                                 1623

<210> 591
<211> 630
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (554)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (558)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (608)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (611)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (615)
<223> n equals a,t,g, or c

<400> 591
ggtgcaggtg taaaccctgt gccttgtaac tgcaaccctc ccgtgcccac ggtatcttcc     60
agaggacgag aacaagccgt aagaaagagc gaaaaggaaa ggatgagaga ataccaacga    120
gaactagaag aaagagaaga aaaattaaaa aagaggccac tgctatttga aagagttgct    180
cagaaaaatg caagaatggc agcagaaaag cattattcta ataccctaaa agcactagga    240
atatctgatg agtttgtttc aaagaaaggc caaagtggaa aagtacttga gtacttcaac    300
aatcaagaga cgaaaagtgt cactgaagac aaagaaagct ttaatgaaga agaaaaaata    360
gaagaaagag agaatgggga agaaaattat tttattgata ccaacagcca ggattcttac    420
arggaaaarg wtgaasccaa tgaggaaagt gaagaagaga aatctgktga agaatcmcac    480
tgratcatya aggtcttctc tctatgccct tgctggtggt tgcagcgtca gggtgtcagc    540
agccgcattt gggnttanaa catctgtggg gaccttttga tatgtgcagg gctggtgatc    600
aaggcatntg naccngaaaa agctgaatcc                                     630

<210> 592
<211> 487
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (464)
<223> n equals a,t,g, or c

<400> 592
ggcacgaggc gcgccaaggc gtcagtcgag gagtcaaggc agcaatgaat cgtgtcttgt     60
gtgccccggc ggccggggcc gtccgggcgc tgaggctcat aggctgggct tcccgaagcc    120
ttcatccgtt gcccggttcc cgggatcggg cccaccctgc cgccgaggaa gaggacgacc    180
ctgaccgccc cattgagttt tcctccagca aagccaaccc tcaccgctgg tcggtgggcc    240
ataccatggg aaagggacat cagcggccct ggtggaaggt gctgcccctc agctgcttcc    300
tcgtggcgct katcatytgg tgctamctga ggraggagag cgaggcggac cagtggttga    360
gacaggtgtg gggagaggtg ccagagccca tgatcgttct gaggagcctg agaytccagc    420
tgctacagag cgagaayttg acggggtgcc cgctggggct gcangaaggg agcccgacag    480
ccgcctt                                                              487

<210> 593
<211> 1467
<212> DNA
<213> Homo sapiens

<400> 593
ctaatccctg gccctcccag ctgtctggga cttcagtgga cccccagccc ctgcccccac     60
tcaccaaggc ctcgctcgtc cctctcgtct gacatgtctg tgtgcacccc cctcctctcc    120
accctacctt ccatcaacca gggcagatcc accgtgccct ggttccccag acattccaga    180
atgccccaca tcattggcac aggagtgggg cagccccgga aggaaccagg gattaggctg    240
taggggggtg agaaggagag aagggaccac cccattcttc tcaagcaagg attgccagcg    300
cgcgctgaca cagtgatggg ctgcccaggg ctggagggga cgctgttcct cccgccgcca    360
ctgcccaacc tttcctgata atcgtggcat gcgccctttc ctcttccctg ccccaccccc    420
tggccgcagc aggycagcac tgcagagttt gggtgctggt ggtgtggctg taggggaggg    480
gagaccacac ccaaggtggg ggctgtggcc atgtgtggcc gtgatgtcga tgatactcgt    540
tttccctgat ccgtggtgtt gcagtccgtt gtcaccagcc ttgtttctag tgtgtatata    600
tgtcgccccc gtgatgcata tatacacagg tattaaatat atcgctctat ataatattat    660
atatgtgtgt ggtatccaag gaatcacttt tatgagggct aaagataaag aatttggcca    720
gaaaatgcag ccatccttgt gtgattagga gggtttcagg ggccactgga ctatttgcaa    780
ggtgacaggg actggagcca tggctcagag gtgattcggg cagccaggga caggagccac    840
cctccccagg cccaactctg ctagcttccc agaccacccc catcgagtgc ggagagagtg    900
ggagtgctca gggaaagaag gtgatttgta tttgtctccc cgctgaaaag aacaggattc    960
aagtccagag ttttcatctt cagcctgtga tctgtccagg gacccttggg atctggggct   1020
tcctggcctg gccagagctg gagcccccac agggtaagga agagagagtg ggaggcagag   1080
tgtgatgggg aggagggaca ggaagaccct tttaatgatg agggtaacta tttcagttgt   1140
gagccttcta gggccccagg ctgggaggct cagaggactg aatctgggac ctgtgttccc   1200
cccggcaggc agggacaaga tggcatggca agcatggggg cggggtgggt ggggagggat   1260
gctgcatttc tcagctgggc agtaatcaat ttaatggtcc tttaaaatgt ctgtgtatta   1320
aaaatttaag aataccacac tttaatatta aatattcata aggtctagta tcttgataat   1380
aatgtagatg ttttaataac aatttttgtc cttcttaaaa taaaatgaaa gaaacttgca   1440
aaaaaaaaaa aaaaaaaaaa aactcga                                       1467

<210> 594
<211> 926
<212> DNA
<213> Homo sapiens

<400> 594
ggagggtgcc tcccagggcc atctgacatg gatgtgtatg tcctcctttg tggacacaca     60
aggaggatcc tttgtgttgc caggtttggt gtgagtgagc cacgaacagg actggagttc    120
ttaccgcttg ctgtgtttct tccctagaaa ggagcgagtg ggactgtgct gctggccggc    180
tcctctttga tggcttcacc ctacaaatcc agcagcccaa agctgtctgg ggccatgagc    240
tcgaactcct tgggaattat aacccctgtc cctattcctg tccatgtgct ctccttcagc    300
gctgactcct ctgccaaagc aggggtctcc aaggatgcca tcgtcacagg ccctgccccc    360
gggtccttcc accatggcct tggcacagtc ttctggctgg cttgcactcc agcccgcccc    420
atgcagcgcc tctcccacac gctgcggtgc ccacccatat cccgcagagt ctgccaggtg    480
cttctcagct tcacgggaaa gggcctgctg taccacggaa attgtgaccg cttcagaggc    540
aaggsttgcc amttgggtct gggtggaatc agaacgtgca ggtctcccag gatgtacact    600
cactgcgccc tttctgctgc ttggtgttct tctggaggag cgtgagttct cagcggagcg    660
cttctcggca cttctgatgt gcctcccatg gagggagccg ggcccttgct gctcaggagg    720
tgcagactgc cccgtgctct gggccttgca gctctgtcgc tagacggttg ttagaggggc    780
agctctaggc tggggcttgc gctgggccgt ggtgggaggc acagtgttta caggctctgg    840
tggcagagca gttggcacac ctgtgggtga atytgcctga tcccctggca tttggtcaga    900
gtacctcaga gcaccccact gctcag                                         926

<210> 595
<211> 787
<212> DNA
<213> Homo sapiens

<400> 595
gggccggaag gaagccgggg agacaggtgg ggtactcggg aagctggagc gggccggcgg     60
tgcagtcacg ggggagcgag gcctgctggg cttggcaacg agggactcgg cctcggaggc    120
gacccagacc acacagacac tgggtcaagg agtaagcaga ggataaacaa ctggaaggag    180
agcaagcaca aagtcatcat ggcttcagcg tctgctcgtg gaaaccaaga taaagatgcc    240
cattttccac caccaagcaa gcagagcctg ttgttttgtc caaaatcaaa actgcacatc    300
cacagagcag agatctcaaa gattatgcga gaatgtcagg aagaaagttt ctggaagaga    360
gctctgcctt tttctcttgt aagcatgctt gtcacccagg gactagtcta ccaaggttat    420
ttggcagcta attctagatt tggatcattg cccaaagttg cacttgctgg tctcttggga    480
tttggccttg gaaaggtatc atacatagga gtatgccaga gtaaattcca tttttttgaa    540
gatcagctcc gtggggctgg ttttggtcca cagcataaca ggcactgcct ccttacctgt    600
gaggaatgca aaataaagca tggattaagt gagaagggag actctcagcc ttcagcttcc    660
taaattctgt gtctgtgact ttcgaagttt tttaaacctc tgaatttgta cacatttaaa    720
atttcaagtg tactttaaaa taaaatactt ctaatggaac aaaaaaaaaa aaaaaaaaaa    780
aactcga                                                              787

<210> 596
<211> 1603
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (477)
<223> n equals a,t,g, or c

<400> 596
gaagccctca tggcaacact aaccaccacc caaacgtcac cgtcgctgct tggcggcgtg     60
gtgattatcg gcggcaccat tattggcgca gggatgtttt ctctgccagt ggtcatgtcc    120
ggggcgtggt ttttctggtc aatggcggcg ctgatcttta cctggttctg tatgctgcat    180
tccggcttga tgattctgga agctaacctg aattacagaa tcggttcgag ttttgacacc    240
atcaccaaag atttgctggg caaaggctgg aacgtggtca acggcatttc cattgccttt    300
gtgctctata tcctgamcta tgcctatatt tctgccagtg gttcgattct gcatcacacc    360
ttcgcagaga tgtcactaaa cgtcccggca cgggcggcgg gttttggttt tgcattgctg    420
gtagcgtttg tggtgtggtt gagcactaaa gccgtcagtc gcatgacagc gattgtnctg    480
ggggcgaaag tcattacctt cttcctcacc tttggtagcc tgctggggca tgtgcagcct    540
gcgacattgt tcaacgtcgc cgaaagcaat gcgtcttatg caccgtatct gttgatgacc    600
ctgccgttct gtctggcatc gtttggttat cacggtaacg tgccaagcct gatgaagtat    660
tacggcaaag atccgaaaac catcgtgaaa tgtctggtgt acggtacgct gatggcgctg    720
gcgctgtata ccatctggtt gctggcgacg atgggtaaca tcccgcgtcc ggagtttatc    780
ggtattgcag agaagggcgg taatattgat gtgctggtac aggcgttaag cggcgtactg    840
aacagccgta gtctggatct gctgctggtc gtgttctcaa actttgcggt agcgagttcg    900
ttcctcggcg taacgctggg tttgtttgac tatctggcag atctgtttgg tttcgacgac    960
tcggctgtgg gccgcttgaa aacggcattg ctgacctttg ccccgccagt tgtggggggg   1020
ctgttgttcc cgaacggatt cctgtacgcc attggttatg ctggtttagc ggctaccatc   1080
tgggcggcaa ttgttccggc gctgttagcc cgtgcatcgc gtaaacgctt tggcagcccg   1140
aaattccgcg tctggggtgg caagccgatg attgcgctga ttctggtgtt tggcgtcggc   1200
aacgcactgg tgcatatttt atcgagcttt aatttactgc cggtgtatca gtaatcagcg   1260
gtgccttatc cgacatttct gctgcctaca caatgcctga ttgcgttcgc ttatcaggtc   1320
tatgtaggac agcgttgcca gctcggataa ggcttcccgc gttaagacac actatcccaa   1380
caactcttcc ttaacatcca tcgccagctc aaacgaatgc agccgcgcct ggtggtcgaa   1440
aatctgcccg ttgaccataa tctcatcggc gtcggtttcg cgcaggatcg actgcaagcc   1500
atgacgcact ttcgctttat cacctaccaa cgacatactc agcgcctgct gcacgccata   1560
ctgctcagac ggtgaccaga actgatccat attttgaatc ggc                     1603

<210> 597
<211> 2150
<212> DNA
<213> Homo sapiens

<400> 597
gcggacgcgt gggtcgaccc acgcgtccgg tttgacccgt cggtcgtgcg tgagaggaaa     60
gggaaggagg aggtcccgaa tagcggtcgc cgaaatgttc cggtgtggag gcctggcggc    120
gggtgctttg aagcagaagc tggtgccctt ggtgcggacc gtgtgcgtcc gaagcccgag    180
gcagaggaac cggctcccag gcaacttgtt ccagcgatgg catgttcctc tagaactcca    240
gatgacaaga caaatggcta gctctggtgc atcagggggc aaaatcgata attctgtgtt    300
agtccttatt gtgggcttat caacagtagg agctggtgcc tatgcctaca agactatgaa    360
agaggatgaa aaaagataca atgaaagaat ttcagggtta gggctgacac cagaacagaa    420
acagaaaaag gccgcgttat ctgcttcaga aggagaggaa gttcctcaag acaaggcgcc    480
aagtcatgtt cctttcctgc taattggtgg aggcacagct gcttttgctg cagccagatc    540
catccgggct cgggatcctg gggccagggt actgattgta tctgaagatc ctgagctgcc    600
gtacatgcga cctcctcttt caaaagaact gtggttttca gatgacccaa atgtcacaaa    660
gacactgcga ttcaaacagt ggaatggaaa agagagaagc atatatttcc agccaccttc    720
tttctatgtc tctgctcagg acctgcctca tattgagaat ggtggtgtgg ctgtcctcac    780
tgggaagaag gtagtacagc tggatgtgag agacaacatg gtgaaactta atgatggctc    840
tcaaataacc tatgaaaagt gcttgattgc aacaggaggt actccaagaa gtctgtctgc    900
cattgatagg gctggagcag aggtgaagag tagaacaacg cttttcagaa agattggaga    960
ctttagaagc ttggagaaga tttcacggga agtcaaatca attacgatta tcggtggggg   1020
cttccttggt agcgaactgg cctgtgctct tggcagaaag gctcgagcct tgggcacaga   1080
agtgattcaa ctcttccccg agaaaggaaa tatgggaaag atcctccccg aatacctcag   1140
caactggacc atggaaaaag tcagacgaga gggggttaag gtgatgccca atgctattgt   1200
gcaatccgtt ggagtcagca gtggcaagtt acttatcaag ctgaaagacg gcaggaaggt   1260
agaaactgac cacatagtgg cagctgtggg cctggagccc aatgttgagt tggccaagac   1320
tggtggcctg gaaatagact cagattttgg tggcttccgg gtaaatgcag agctacaagc   1380
acgctctaac atctgggtgg caggagatgc tgcatgcttc tacgatataa agttgggaag   1440
gaggcgggta gagcaccatg atcacgctgt tgtgagtgga agattggctg gagaaaatat   1500
gactggagct gctaagccgt actggcatca gtcaatgttc tggagtgatt tgggccccga   1560
tgttggctat gaagctattg gtcttgtgga cagtagtttg cccacagttg gtgtttttgc   1620
aaaagcaact gcacaagaca accccaaatc tgccacagag cagtcaggaa ctggtatccg   1680
atcagagagt gagacagagt ccgaggcctc agaaattact attcctccca gcaccccggc   1740
agttccacag gctcccgtcc agggggagga ctacggcaaa ggtgtcatct tctacctcag   1800
ggacaaagtg gtcgtgggga ttgtgctatg gaacatcttt aaccgaatgc caatagcaag   1860
gaagatcatt aaggacggtg agcagcatga agatctcaat gaagtagcca aactattcaa   1920
cattcatgaa gactgaagcc ccacagtgga attggcaaac ccactgcagc ccctgagagg   1980
aggtcgaatg ggtaaaggag cattttttta ttcagcagac tttctctgtg tatgagtgtg   2040
aatgatcaag tcctttgtga atattttcaa ctatgtaggt aaattcttaa tgttcacata   2100
gtgaaataaa ttctgattct tctaaaaaaa aaaaaaaaaa aaaaaaaaaa              2150

<210> 598
<211> 1495
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (968)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1461)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1469)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1492)
<223> n equals a,t,g, or c

<400> 598
gctcgtgccg aattcggcac gagcaggatc cgggcagggc cgagtgtgag ggtcccccca     60
ggctgggaca tctcgtcgct gaacctggcc gaggcgatgc ggcgcgcgaa ggtgctggac    120
tgggggctgc aggagcaact gtggccgcac atggaggccc tgcggccccg gccttctgtt    180
tacatccccg aattcatcgc ggccaaccag agcgcgcgcg cggacaacct catcccaggc    240
tcgcgtgcgc agcagctgga gcagatccgc agggacatcc gagacttccg gtctagcgcg    300
gggctggaca aagtcatagt gctgtggacg gcgaacacgg agcgcttctg tgaggtgatt    360
ccaggcctca acgacacagc cgagaacctg ctgcgcacca ttgagctcgg tctggaggtg    420
tcgccctcca cgctcttcgc cgtggccagc atcctggagg gctgtgcctt cctcaatggg    480
tctccgcaga acaccctggt gcccggagct cttgagctcg cgtggcagca ccgggttttt    540
gtgggcggag atgacttcaa gtcaggccag accaaagtca agtccgtgct tgtggacttc    600
ctcattggct ccggcctcaa gaccatgtcc atcgtgagtt acaaccacct gggcaacaac    660
gatggggaga acctrtcggc gccattgcag ttccgctcta aggaggtgtc caagagcaac    720
gtggtggacg acatggtgca gagcaaccca gtgctctata cgcccggcga agagcctgac    780
cactgcgtgg tcatcaagta tgtgccgtac gtgggtgaca gcaagcgcgc gctggatgag    840
tatacctcgg agctgatgct gggcggaacc aacacactgg tgctgcacaa cacgtgtgag    900
gactcgctgc tggccgcacc catcatgctg gacctagcgc tgctgaccga gctgtgccag    960
cgcgtganct ttctgcactg acatggaccc cgagccgcag accttccacc ccgtgctgtc   1020
cctgctcagc ttcctcttca aggcgccact agtgccgccc ggcagcccgg tggtcaatgc   1080
gcttttccgc cagcgcagct gcatcgagaa catcctcagg gcctgcgtgg ggctcccgcc   1140
acagaaccac atgctcctgg aacacaaaat ggagcgccca gggcccagcc tcaagcgagt   1200
tggacccgtg gctgccacct accctatgtt gaacaagaaa ggaccggtac ccgctgccac   1260
caatggctgc accggtgatg ccaatgggca tctgcaagag gagcccccaa tgcccaccac   1320
ctgaggcccc ggtcacacag tttctcggct cttcctcccc gctgcccccc acgaccctac   1380
cttgaaggcc cccacaaata aaggcgctgc cactcaaaaa aaaaaaaaaa aaaaaaaaac   1440
tcgaaggggg gggcccggta nccaaattng gccctaataa ggggagtcgt antta        1495

<210> 599
<211> 1436
<212> DNA
<213> Homo sapiens

<400> 599
acggatccgt acattgccga gaaagaataa tttgccaggc atttgactgg cagacgtccc     60
cgccgttggt gattaacgac ggcgttttga ttaactaaca tgagaaccca tacgacgcca    120
tgagcgacga caattcacac agtagtgaca cgataagcaa caagaaggga tttttctccc    180
tgttactcag ccaacttttc cacggtgaac cgaaaaaccg tgacgaactg ctggcgctga    240
tccgtgattc cgggcagaac gaccttatcg acgaagatac gcgcgatatg ctcgaagggg    300
tgatggacat cgcagaccaa cgcgttcgga gcatcatgat cccccgctcc cagatgatta    360
ccctgaaacg caaccagacg ctggacgaat gtcttgatgt catcatcgag tccgcccact    420
cacgtttccc ggtgattagc gaagacaaag atcacattga agggattctg atggcgaaag    480
acttgctgcc gtttatgcgc agcgatgctg aagccttcag catggacaaa gtgttacgtc    540
aggcggttgt cgttcctgaa agtaagcgcg tagaccggat gctgaaagag tttcgctctc    600
agcgttacca catggcgatc gttattgacg aattcggtgg ggtttccggt ctggtgacca    660
ttgaagacat cctggaactg attgttggtg agattgaaga cgagtatgac gaagaagatg    720
atatcgactt ccgtcagctg agtcgtcata cctggaccgt acgcgcactg gcttccattg    780
aagacttcaa cgaagcgttc ggcacccact ttagcgatga agaagtcgac actatcggtg    840
gtctggtgat gcaggcattt gggcatcttc cggcgcgtgg cgaaactatc gacatcgacg    900
gttaccagtt caaagtggcg atggccgaca gtcggcgtat tattcaggtt catgtcaaaa    960
tcccggatga ctcaccccag ccgaagctgg atgaataaaa ccgaaactgg atagataact   1020
acatggcttt tgcctcatta attgaamgcc agcgcattcg cctgctgctg gcgttattaw   1080
tcggtgcctg cggaacgctg gccttctctc cttacgacgt ctgctgcggc gattatttcg   1140
ctgatggggc ttcaggcgtt gacctttaac cgccgtccac tccagtctgc cgctattggc   1200
ttttgctggg gatttggcct ctttggcagc ggtattaact gggtctatgt cagcatcgcg   1260
acctttggcg gaatgcctgg cccggttaac atcttcctgg tggtgctgct ggcggcgtat   1320
ttgtcgctgt ataccggact gtttgctggc cgtgtgtcgc gtctgtggcc gaaaaccacc   1380
tggtgccgta gcgattgccg cccctgccct ctggcaagtg accgagtttc tgcgcg       1436

<210> 600
<211> 1215
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (27)
<223> n equals a,t,g, or c

<400> 600
ccacgcgtcc gcggtacntg ntgtaanttt ttcatttttt gagtcaagag actgctcctt     60
gtactgggag acactagtag tatatgtttg taatgttact ttaaaattat ctttttattt    120
tataaggccc ataaatactg gttaaactct gttaaaagtg ggccttctat cttggatggt    180
ttcactgcca tcagccatgc tgatatatta gaaatggcat ccctatctac ttactttaat    240
gcttaaaatt atacataaaa tgctttattt agaaaaccta catgatacag tggtgtcagc    300
cttgccatgt atcagtttca cttgaaattt gagaccaatt aaatttcaac tgtttagggt    360
ggagaaagag gtactggaaa acatgcagat gaggatatct tttatgtgca acagtatcct    420
ttgcatggga ggagagttac tcttgaaagg caggcagctt aagtggacaa tgttttgtat    480
atagttgaga attttacgac acttttaaaa attgtgtaat tgttaaatgt ccagttttgc    540
tctgttttgc ctgaagtttt agtatttgtt ttctaggtgg acctctgaaa accaaaccag    600
tacctgggga ggttagatgt gtgtttcagg cttggagtgt atgagtggtt ttgcttgtat    660
tttcctccag agattttgaa ctttaataat tgcgtgtgtg tttttttttt tttaagtggc    720
tttgtttttt tttctcaagt aaaattgtga acatatttcc tttatagggg cagggcatga    780
gttagggaga ctgaagagta ttgtagactg tacatgtgcc ttcttaatgt gtttctcgac    840
acattttttt tcagtaactt gaaaattcaa aagggacatt tggttaggtt actgtacatc    900
aatctatgca taaatggcag cttgttttct tgagccactg tctaaatttt gtttttatag    960
aaatttttta tactgattgg ttcatagatg gtcagttttg tacacagact gaacaataca   1020
gcactttgcc aaaaatgagt gtagcattgt ttaaacattg tgtgttaaca cctgttcttt   1080
gtaattgggt tgtggtgcat tttgcactac ctggagttac agttttcaat ctgtcagtaa   1140
ataaagtgtc ctttaacttc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1200
aaaaaaaaaa aaaaa                                                    1215

<210> 601
<211> 1564
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (988)
<223> n equals a,t,g, or c

<400> 601
gctgccccgc gagtattgac cttaacgagt ggctggccag caacagtgcg cggtngcctg     60
ggggcgggcc ccctccctcc tccctgctcc tcctcgaagc ccctcctcaa gggggacccc    120
cacggctggt gctcagcagc cccctgccgc gaggggagaa tgtggcccgt ggacgggcag    180
agctcaccca gccgagctcc tgcacctgtt gctggaagca ggggtggacg gggcggctca    240
gctctggcgt ttttcacatc tggctccttc tcttctcttc cagccacgac gtttttccac    300
cacatcaacc tgcagtatag caccatctcg gagttctgca caggagagac gtgtcagacg    360
atggccgtgt gcacacacag tactactggt atgacgagcg ggggaagaag gtcaagtgca    420
cggccccaca gtacgttgac ttcgtcatga gctccgtgca gaagctggtg acggatgagg    480
acgtgttccc cacaaaatac ggcagagaaa ttccccagct cctttgagtc cctggtgagg    540
aagatctgca gacacctgtt ccacgtgctg gcacacatct actgggccca cttcaaggag    600
acgctggccc tggagctgca cggacacttg aacacgctct acgtccactt catcctcttt    660
gctygggagt tcaacctgct ggaccccaaa gagaccgcca tcatggacga cctcaccgag    720
gtgctatgca gcggggccgg cggggtccac agtgggggca gtggggatgg ggccggcagc    780
gggggcccgg gagcacagaa ccacgtgaag gagagatgag ccccccgggc cggacagggg    840
cacacgtgtg caaagagacg gtggtgtgtg ttctctcctg catctgcgtg tgcacacatg    900
tgctgggcac gcgtgtggtg aggtctgaga gggccccggg ctgcactggt gtgggctgca    960
caggcacaga cgcagacggc cccggccntg tcctgtggcc ccctgtcgga tggatgcgtg   1020
ccgtttgtag agaagagcct ttgggcccat tcactcgttc agcagacacg catgggactg   1080
atgctttgag ttttcttctg tggggttttc ctttctctgg tctctgtgca gcccctgccc   1140
tccctcgggt gctgctggcc tcaaaggagg aactcgtggg gggagggtgt gatttgcaga   1200
cctgggtctc tgctctgctc tgggggtggg gcttgctttc acagagaccc tccttccctc   1260
tcacccctcc tctcccggcc tcgccaggag tcttggctgt tggcagctca gaggtggggg   1320
aggcctgtgg tgtgagtgcc ctgcacctgc tcctgctcct gtcacccctt cctgctgcct   1380
cctccatgcc caaggaacac ccatggtgca gtcctcaggc aaggccagga cggggctgag   1440
gccctgcgtg gagatgctgc accagcggaa ggctgagacc cgcttacctt agttcatctg   1500
ttcactcgta ataaaaagaa ttctctcagg tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1560
aaaa                                                                1564

<210> 602
<211> 595
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (517)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (518)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (583)
<223> n equals a,t,g, or c

<400> 602
ggcacgaggg ctgagctgct gcttacccta ctccctgggg ctgaaggtgt cagtggatgt     60
cagtggcatg tcagtggctg caaccccgag aggaggggtg ccacagcaac ttggatccta    120
aggctgtcag ggcaccgtgg caatggaagc cgctggggtg gtgcagtgct gttgtggcac    180
aggcctagga gggagagggc tgctgccact catgtccagg catgtcagaa caccatggcg    240
gtaaggctcc agggacagca gggtgcagcc atgactaggg ccccagrggc agggtacagt    300
gctggtgact tcagttcctg ggacggctgg gcctgcagca gcctagagct cagagctctt    360
tacgtgattt cagagggtcc tagtgcctct ggtgtggttc ctcaagaaca cagatatcag    420
ctccatttcc aggatccgtc tgaaaagatg ataatgtttc agtctgtgtt ctgcctcctg    480
ttctttgctg agctgtgctg catagcagga ataatgnntt ttagtaaggg aaagtttccc    540
cttcattgaa gatcacactt tggaatttct gcctcaaact gtnatacatt tcccc         595

<210> 603
<211> 1668
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1013)
<223> n equals a,t,g, or c

<400> 603
nggggggggg ggtntntttn tttttttttt tttttttttt tttttttttt tttttgggga     60
gtggataaag tgcatttatt ttcttctatg tttgtttttg taaaaaggag aaaggaagca    120
aaagactcct tcctttcaga cccagtgtcc actgagcttg gagggggtgg agccgggacc    180
agccccctag gaaaaggtgt aggaatagaa ggcaatggca ttggcgctat agtccatggg    240
gaggaggtgc ccgatgtgcc tggcccctag gctggcccca cccagagcgg aggagtgcct    300
cagcttcatc agggtgaagc tggagaagaa gttctgagcc tggatctctc tgccctgggt    360
cagcgccara agaaaacctt ccttcagcag ctcccagctc ttccacacag agcccacgca    420
caggatgggg agtccaatct tgccctggaa caagaccggg tcaatctcgg gcaacactgc    480
tacgatgtgt ctgcccagca tctccccagc cttcctgaag atatagcggg aaagggggtc    540
tccctgctga gcaccttctg caattttccg gcaaaaccca gcaaacctgc atttatcaaa    600
gtccctatac aggtgagtga gtatccctag ccgatctggc acctggaaat agtggaacat    660
ggcctgtttg acgtagccga tatcatgagg agccgcctct aggttgtcaa tggagtcaaa    720
cactattttc actgcttggt gtgcgatcca gtaggctgaa ccctcatcac ccatcatatg    780
gccccagccg ccgcagccac tctcggagcc atcagggttg atgagcctgc agttggagcc    840
tgttccagat atgagcacaa ctccaccatc cggtgtagct gtggcgatgg agccggcggc    900
atcggtggtg attaagtagc tttcactcag gtagggaaat cggtccctca gctcctcgat    960
caggatcctc cccgcgtcct cctggtcccc accgctcaga gataggccca agnttcgcag   1020
cggtaccaga ggatccaccc ctgctttccg tttggccctg ttcaccatct cattgatcct   1080
ctccacacac ttgtctgtcc cgatcagcca gtggtttgtg ctcagtccat ctgcttctgc   1140
caggatcttc ccatcctctg agactaaaag gacctcggat cgtgtgcctc ccccctctac   1200
acccccatag atcgcggcca tgctgctgct accgtcgctg ctggtcccgc cgtttgcgtc   1260
tctccccgcc tgacacctcc ttccctccag ctgtctgggc accgccccac ttcccgtgac   1320
ctcccgcgca ccagctgact ccctgtgcgc gtgcgcatgc gcggggcggg gcgccggtag   1380
gagccgggga trgctgcgtc cctcaggctg tcttccttct ggtgtctcct ccaggtggag   1440
cgactgcggt ccgcagcggc ccctcccgtc ctcctggatc ctgcttccag agatggacac   1500
taatcccaag aggaggaatc aaagaggggt atctaggtcg gtcggaccct taggacacat   1560
cactgacctg cctgcctgtt aaacgcccgg aattgctggc awtcccgctt aagttgcgct   1620
gccactgsty ttggcgctwa gttgtgaagc agttcggcca aaccccgc                1668

<210> 604
<211> 621
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (574)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (587)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (621)
<223> n equals a,t,g, or c

<400> 604
gcccacgcgt ccgatcttgc agaagaggaa acaagctcag aggttaagta acttgttcca     60
aactatgcag acagtgagac agaaagccag aattcagagt cacatttatc tgatactgaa    120
gtctctgaat attgcttctc tcctgacctc atttcctacc tttaacccca tgattaccac    180
ctctatctta tctacttaac ttacttaaat ccttaccata catgcagtat aagggcaggg    240
tgggacctgg tcatctttcc cataatttta tctggtccct agggccctcc ccctttcaca    300
agactcgaat atacttttcc tatccagtca tttgccccaa catcccagcc ttttgtcatc    360
tccattctct atatctgcca tggsccacct ttacatccac cttgcagctt tactctgtca    420
tttatgctcc ctgtcctgcc cctccgctat cctacttttc ctcacatgtt ctgatcccac    480
tgcctcacat gctgstgtcc ttcctgtcca cccatgtcat tcttctaagt ctaatctgna    540
accctcagcc accctgctat cctgcctaaa ctgncttgct taactgncac tctggttatt    600
ggtactttgn ctattactgg n                                              621

<210> 605
<211> 1034
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1014)
<223> n equals a,t,g, or c

<400> 605
gaattcggca cgagctcatt tgcacccagg caaccctaat atctcactgt cgagggtaca     60
ggctgctgtg gctatccgta cctgggtgac acaccactcc aaaatttaat gacttaaaca    120
acaaccattt tgttgctcaa caatgtgaac agctcagtag ggatggcttg tgtctgctac    180
tcatgatatt gactggcact attcaactgg ggctggagag tccaagatgg tgtcattcac    240
atgtctggca cctcagctgg ggagactcca tcacctgggg cttggctggg gttgttgggc    300
ttcttttctt ctcatgggct ccctcctgta tctgggccct agttctcctc cacatgtcct    360
ctgtttccat gtgttgtctc atctatcaag acctctctcc acttgacctc tctctccaac    420
agtacagtgt ggactctgca catggtgaat tttcctctga gcaaaatcag gagttacaag    480
acaccttcag ggctggactt aggaatctca aattttcatt tatgacaaat gtgtcttctg    540
gtcagagcaa gtcacaagag cagtccagat tcaaagggaa aggtccacct ctggatagga    600
ggagtagcac tcatgtccgt gggaaaatgt ttggtggcct tgcatgcaca ttgatactac    660
cttgactctc catatcagag ttctgtgtaa ggggggagta ttgcaggagt cagacaaatg    720
aagatcgagg tacagaacaa gttttgttgg aagtaaagct aaattggttt aggcaacaat    780
gggcttaaca taaacttgtt ttaggcaaca gcgagcgtcc ttcttctttg accctgagtt    840
ggatttactc acttgtttaa atgtacaacc tcagamcttc ctagccttag gggcagagcc    900
ttcctgggag agttcaccca acaaaggagg atggagcagg gcagacacta ggggcagarg    960
gtaggtgcga gccacctgag ttcattcgtc cttctagcct cacaacccac tcantccttc   1020
ctgatcccat ggaa                                                     1034

<210> 606
<211> 817
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (668)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (789)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (816)
<223> n equals a,t,g, or c

<400> 606
gcggacgcgt gggcggacgc gtgggcggac gcgtgggcgg gtcgcttggt ggctccgtct     60
gtctgtccgt ccgcccgcgg gtgccatcat ggcggacgcg gccagtcagg tgctcctggg    120
ctccggtctc accatcctgt cccagccgct catgtacgtg aaagtgctca tccaggtggg    180
atatgagcct cttcctccaa caataggacg aaatattttt gggcggcaag tgtgtcagct    240
tcctggtctc tttagttatg ctcagcacat tgccagtatc gatgggaggc gcgggttgtt    300
cacaggctta actccaagac tgtgttcggg agtccttgga actgtggtcc atggtaaagt    360
tttacagcat taccaggaga gtgacaaggg tgaggagtta ggacctggaa atgtacagaa    420
agaagtctca tcttcctttg accacgttat caaggagaca actcgagaga tgatcgctcg    480
ttctgctgct accctcatca cacatccctt ccatgtgatc actctgagat ctatggtaca    540
gttcattggc agagaatcca agtactgtgg actttgtgat tccataataa ccatctatcg    600
ggaagagggc attctargat ttttcgcggg tcttgktcct cgccttctag gtgamatcct    660
ttctttgngg gytgggtaac tcactgggct acctcgkcaa tacctatgca ctggamagtg    720
gggkttctac catgaatgaa atraarakta ttctcaagct gcacagggat tttttgcgag    780
atggtgganc tatccctttg ggcttggctt caaacnt                             817

<210> 607
<211> 1749
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (204)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1704)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1708)
<223> n equals a,t,g, or c

<400> 607
tttttttttt tttttttttt tttttttttt tataagtttt cactactatt tattttgaag     60
agttttctgt aatggaacta tttcttctga agatttcaga aaagcttttg atgtctgtta    120
cctcaccatg tctaagaggt ggaaggaact gagagtcatc ttcccgctca tttcacaagt    180
gaggaagcca aggcccagac ggcnaagggt cttgcccagc atcacccagc agggatggct    240
cagctggacc cacaggcaaa gacagtacct gccctcccca cagccactcc cctgggcagc    300
ggctgccatc cagatacaca gagataggga ggaaggaaga tgatggacag acaggcagat    360
acataggtaa gagggtttgg gaataacaca tagatatttt aacttttcga gagaggaaaa    420
ggaaaaaatg gcttgtgata gacatttttt ggacccacca aagccttgca tatctgaaaa    480
gaaaattact ttggctttct ggaaacatta aactgcattc aatcaaaaaa acagactaaa    540
ttataacaca tcacaaccag taagcttcat agcagccgca gtaggagtga tggcatttcg    600
tgttggtgtg cgcgtacacg tggaaaggaa gtttgcaggg caacaaggtc agcaagaacc    660
agacctcaga ttgtttcact caccacagaa gaaaaacacc catggcaatt cccttttgga    720
aagttaaagc ttatctcctc ggaatgaagt tccaaagaca tccatttcca cagaagatgg    780
aggaaaaaag acaattacat ttcaaatctg taagtcacaa atagacaggc agagttctgg    840
cgagccgtgt cacagttaac cagtttgagg acatcagtgt cttcccccag agtctgtaaa    900
cacgcagcca gtcaatttcc taatgaatgc ttccctttaa caaaggctgc ttcagtcctc    960
cctgcaggcc tactagagtc ttccagcagc acatctcagt gggagccatc agattttcca   1020
aaaaatcttc tttctataga ggatgtaggc aatgagcacc cagagggcag tggcgacgat   1080
gttctgagtc aggtgctcct tgtgggactg gttgtccttc agcttccact gaaaggggaa   1140
gtagttctca aacacctcgt ggccgacgta taccagaatg gaattcattc ctggataaaa   1200
gaatggggtt cctgtccaca gccccttcac atccacaact gggtacagga ccagcaggat   1260
gaagaaggca aaagaactga gcgtagtgac atacgaaagg gaccagagat ttttgtttac   1320
tggaataaag ccttcatttt cagaaacctt cgtcagagca acagaaatga gcccaagaat   1380
acaacaccaa gcagtgaatc gaatcaggat gtctttggtc cgagccttgt aatacaatag   1440
tatttttcct gcctgaactc ctaaaaaggc catcacgatg gagttgatgg tgcccaggat   1500
gccctcgggg tcataggcca cctcggtgtg gtaaagtaca gcagaagatg ggtgctggta   1560
aaggtgatcg tctcccagca gcaggcggtc gatgtagcct gcagctcctc cagtgcaatt   1620
tggatacttg ccaaaatctc caatgccccc aggaccaaga taaccagtag ggcacccagg   1680
gactggcagg aggaatgtca agcnccanca caggscttcc agcaccagga tgagcagcca   1740
ctggggccc                                                           1749

<210> 608
<211> 812
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (723)
<223> n equals a,t,g, or c

<400> 608
gnantgcccg ggtncnaccc acgcgttccg gaagcggctc cgaggaaggc ctgtgggagt     60
ctcggagacg tgtctgtctg tgaggcgctg ggtgcacgtc cccagggctc tgggctagga    120
aggcagcggc gaggtgcctc cccacgtacc cctcgcgggc ccagccgagc aacgtggggc    180
gaaggcggcg gcgaaggccc gggctgggag cgttggcggc cggagtccca gccatggcgg    240
agtctgtgga gcgcctgcag cagcgggtcc aggagctgga gcgggaactt gcccaggaga    300
ggagtctgca ggtcccgagg agcggcgacg garggggcgg ccgggtccgc atcgagaaga    360
tgagctcaga ggtggtggat tcgaatccct acagccgctt gatggcattg aaacgaatgg    420
gaattgtaag cgactatgag aaaatccgta cctttgccgt agcaatagta ggtgttggtg    480
gagtaggtag tgtgactgct gaaatgctga caagatgtgg cattgttgct actctttgat    540
tatgacaagt ggaactagcc aatatgaata gacttttctt ccaacctcat caagcaggat    600
taagtaaagt tcaagcagca gaacatactc tgaggaacat taatcctgat gttctttttg    660
aagtacacaa ctataatata accacagtgg aaaactttca acatttcatg gatagaataa    720
gtnatggtgg gttagaagaa ggaaaacctg ttgatctagt tcttagctgt gtggacaatt    780
ttgaagcccg aatgaccaat aaataccagc tt                                  812

<210> 609
<211> 673
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (578)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (595)
<223> n equals a,t,g, or c

<400> 609
gaattcggca cgagtgacca gtaatcaaat gcatcttctg gccggcctgg cgatgacccg     60
gcatgctgtc tgtccaaacc ctgatgatgg caggtgtcaa ccgagaccct gcactctgcc    120
cctgcctctg tgcctcactc tggcggggca gctccgaggg gctatgcaag ggcccctacc    180
tgggcaagac ctctgcagag cccagcccca gctggcaggg gtgttcatgg catggagtcc    240
cctgcccgcg gcagacagcg atgtctcctg gcaccaaggc cactgcgcct gcggtttcag    300
attccttccc tgtcccgtcg ctggtgttgt gggtgawtta tttgctgctt ggcagaactc    360
agcagccctt aggaaatgga tgtcagctta ttgtgtttgg gggarggatg gatatgtact    420
ttccgstaca taaactggag ccttcctagc tttamgtccg tctgcccaca rgctgtgttg    480
ggagcctcgg sctggccctc acccactcac cttcttcatg gtctttgcct gccaacagtg    540
tctgcagcct ttccaagccc caagttcatg aaaacggncc atagtaagag atatntgttt    600
taaacatgaa cccggattca ttgtcatctg atattagaaa tctgaattca aagatttcct    660
ggtgcgataa gga                                                       673

<210> 610
<211> 2201
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (852)
<223> n equals a,t,g, or c

<400> 610
gctccaggcc cttcttcagg gacatcgttt tctacatggt ggctgtgttc ctgaccttcc     60
tcatgctctt ccgtggcagg gtcaccctgg catgggctct gggttacctg ggcttgtatg    120
tgttctatgt ggtcactgtg attctctgca cctggatcta ccaacggcaa cggagaggat    180
ctctgttctg ccccatgcca gttactccag agatcctctc agactccgag gaggaccggg    240
tatcttctaa taccaacagc tatgactacg gtgatgagta ccggccgctg ttcttctacc    300
aggagaccac ggctcagatc ctggtccggg ccctcaatcc cctggattac atgaagtgga    360
gaaggaaatc agcatactgg aaagccctca aggtgttcaa gctgcctgtg gagttcctgc    420
tgctcctcac agtccccgtc gtggacccgg acaaggatga ccagaactgg aaacggcccc    480
tcaactgtct gcatctggtt atcagccccc tggttgtggt cctgaccctg cagtcgggga    540
cctatggtgt ctatgagata ggcggcctcg ttcccgtctg ggtcgtggtg gtgatcgcag    600
gcacagcctt ggcttcagtg accttttttg ccacatctga cagccagccc cccaggcttc    660
actggctctt tgctttcctg ggctttctga ccagcgccct gtggatcaac gcggccgcca    720
cagaggtggt gaacatcttg cggtccctgg gtgtggtctt ccggctgagc aacactgtgc    780
tggggctcac gctgctggcc tgggggaaca gcattggaga tgccttctcg gatttcacac    840
tggctcgcca gngctaccca cggatggcgt tctccgcctg ctttggcggc atcatcttca    900
acatcctcgt gggtgtgggg ctgggctgcc tgctccagat ctcccgaagc cacacagaag    960
tgaagctgga gccagacgga ctgctggtgt gggtcctggc aggcgccctg gggctcagcc   1020
tcgtcttctc cctggtctca gtcccattgc agtgcttcca gctcagcaga gtctatggct   1080
tctgcctgct cctcttctac ctgaacttcc ttgtcgtggc cctcctcact gaatttggag   1140
tgattcacct gaaaagcatg tgactgaagc cgcttagtgc tgtggcctca ctgcaggcag   1200
gagccccgcc cctcctgccg ggggaggccc agggaccgga gcatttctgc aaggcccttg   1260
tgggcacgag agtgcggccc ttgctgctgg agatctgagg tcactgctgt ragctgggag   1320
aactgctgtg tacctcttgc tgccagcacc caacagcctt gccgtgggga ccttggaaac   1380
ctggctttgc tctggacaaa gggttccaga gagaagctag aagtccccct tgaatgaccc   1440
ccagagcccc tctgagaagg gctggagttt gggggaaggg gatggctgga tgtgctccag   1500
gccatgctgg aggtaccccy gaggcacagg cactgcccgt tcccyttgcc tgggcttcar   1560
gccttctggc accttctcag gacacaagtg gctgcccaac cctgactcag agaatgaggg   1620
tggcttggac ccctgggaat caggccgccg agggctgagc tccagagccg caccatctgc   1680
cacaaacaga attcgagaca tacttaattt tgaatttctc cttgccacgt taataaagcc   1740
aaaagcagcg ggtgctattc gtggcaacac acttcactga acccacttgc ttccaaaacg   1800
atgccagccc gaggcactgc tacgccagca gctgccacat gggatggtgg ctcaggcgct   1860
ccctccagga ttctgcccct gcctgtccac agactccttt gtgctggaac ctgggctcct   1920
ccagctgcca ggcaggagtc ggtaggactg tgcctgtgcc tccctcagcg gggccctggg   1980
cggggttcca aggcctgcga gctgggaaag gacagatgag gggacctcgt gccttcttgc   2040
tgtcatgcaa tgaccccgcc ttatgttgcc gaaataagca actcttaggt ttgcctgact   2100
gccttatgct ggtaaagaaa agggattcaa ctgtctcttt tccaaataaa aaaaaagtca   2160
aaatttcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                       2201

<210> 611
<211> 2796
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2774)
<223> n equals a,t,g, or c

<400> 611
ntncacgcgt ccggggcgcc agacccggct ttgccgtccg gctattagcc tactgtggct     60
agtcaccccc ggggtcccgg ccttctcggg ctggggccgc cgccaccgcg gcaggacggg    120
gaggcgggcc atggcgtcct gcgtggggag ccggacccta agcaaggatg atgtgaacta    180
caaaatgcat ttccggatga tcaacgagca gcaagtggag gacatcacca ttgacttctt    240
ctaccggccg cataccatca ccctgctcag cttcaccatc gtcagcctca tgtacttcgc    300
ctttaccagg gatgactctg ttccagaaga caacatctgg agaggcatcc tctctgttat    360
tttcttcttt cttatcatca gtgtgttagc tttccccaat ggtccgttca ctcgacctca    420
tccagcctta tggcgaatgg tttttggact cagtgtgctc tacttcctgt tcctggtatt    480
cctactcttc ctgaatttcg agcaggttaa atctctaatg tattggctag atccaaatct    540
tcgatacgcc acaagggaag cagatgtcat ggagtatgct gtgaactgcc atgtgatcac    600
ctgggagagg attatcagcc actttgatat ttttgcattt ggacatttct ggggctgggc    660
catgaaggcc ttgctgatcc gtagttacgg tctctgctgg acaatcagta ttacctggga    720
gctgactgag ctcttcttca tgcatctcct ccccaatttt gccgagtgct ggtgggatca    780
agtcattctg gacatcctgt tgtgcaatgg cggtggcatt tggctgggca tggtcgtttg    840
ccggttttta gagatgagga cttaccactg ggcaagcttc aaggacattc ataccaccac    900
cgggaagatc aagagagctg ttctgcagtt cactcctgct agctggacct atgttcgatg    960
gtttgacccc aaatcttctt ttcagagagt agctggagtg taccttttca tgatcatctg   1020
gcagctgact gagttgaata ccttcttctt gaagcatatc tttgtgttcc aagccagtca   1080
tccattaagt tggggtagaa ttctctttat tggtggcatc acagctccca cagtgagaca   1140
gtactacgct tacctcaccg acacacagtg caagcgcgta ggaacacaat gctgggtgtt   1200
tggggtcatt ggtttcctgg aggccattgt ttgcataaaa tttggacaag atctcttctc   1260
taagacccaa atactctatg ttgtgctttg gcttctttgc gtggctttca ccactttcct   1320
ctgtctgtac ggcatgattt ggtatgcaga acactatggt caccgagaaa agacctactc   1380
ggagtgtgaa gatggcacct acagtccaga gatctcctgg catcacagga aagggacaaa   1440
aggttctgaa gacagcccac ccaagcatgc aggcaacaac gaaagccatt cttccaggag   1500
aaggaatcgg cattccaagt caaaagtcac caatggcgtt ggaaagaaat gaaaaaccct   1560
ggttaatcaa agatgttcca gagtgcctag aactgagagg gaaatggaac tcatttggaa   1620
ctccccgtga ggaggtcgag gcgcacaggg caagcaggaa gaggcgaggg cacttggggg   1680
tcattatttg agatcgtaag tcttgtttcc cacagacctg gccgcgtcag gcagatcatc   1740
gcctgggggg cctttgccaa cgtggggtct cttctaactt cagcacttga catgcggtca   1800
ccggtggcag cgcggtgtgt tgaagggaaa cggtagctat tcattcacag ttgccaagag   1860
cagctccgcg cctgctggat cgtggatgca gcgtaaacat cttccttcag acgaggcatt   1920
aaccccatgg ttaatggact ggtcaccagt ttttatttta tttttatgaa tctacctttc   1980
cattgattga tttaagttca ggccactttt ctgtctttta tttggttact gttgttattt   2040
gtttttaagt taggatgctt tttaacagcc tttagaagcc gctgctgaaa ttgatactgg   2100
gggaagggtt ccccttcctt ctagagcaga aaagggagag aggtgttgta ttcctgtttg   2160
gtaacctcag tctcctgtaa gacctcctac cacatggcga gtatacacca atcaggagag   2220
ggtagctgcc tgcataggag cctcgcttcc gattattccc ttcccaatat tattcatcca   2280
gacttagcca cagtgcacaa aagcaaacct gctagagagg cagtgaacac cacagcttct   2340
ccccagctag gtgcctttta catcgggttt gttctccttc catggtgtgt tgctgacatt   2400
gtcactgagt cccatgtgag gtgctggtga gtattacctt tcatctgtgc catgctctag   2460
aaccttgacc ttgatagttc accacctctg atggatccct gttttaaaag gcaaacctgc   2520
trgrgaggca gtgaacacca cagcttctcc ccagctaggt gccttttaca tcgggtttgt   2580
tctccttcca tggtgtgttg ctgacattgt cactgagtcc catgtgaggt gctggtgagt   2640
attacctttc atctgtgcca tgctctagaa ccttgacctt gatagttcac cacctctgat   2700
ggatccctgt tttaaataaa aacgattcac tttaaagcct aaaaaaaaaa aaaaaaaaaa   2760
aacttggggg gggncccgta acccaattgg cccttt                             2796

<210> 612
<211> 1128
<212> DNA
<213> Homo sapiens

<400> 612
cttacaaatg attactacag gaatagtggc cacttaatgt cagttactcc ggtggaagaa     60
tttatctagt tttttttttt ttcttttttg gaaggatggt gtgaaaaata gcaagattag    120
agaatgagtt gtatagtttt ttctatcaca tttcatctaa aatgatttga aggacttttg    180
aagattttta ccaacatcct taaatcaact ccaggttgga tgaacaactg atttaaaaca    240
aactaagaga acattaacta gatgtgggct ttttaaaata tataggtatt gcatttccta    300
ccttgttatt tattccactt tgaatacttt agagggctta actttcaact ctttaaggta    360
gtaatggata gttttatact tgttctcaca aaattgttat ggtcagttta tatcattgct    420
ccatgcattg attataaaaa ttcagtatta attttttctg atcttataag ctttatagga    480
gttttctttt ctcttataaa gtgtttcacc ttatgtaaaa caaatgcctg cttgcatatt    540
ggaagatgtt gaaattagtt ttagacaaaa gtggtccatc aattcagaca ctctgcttgg    600
atgccttacc cttttcatta gtgcattctt tgcttctgaa acttggcaga aactcgttag    660
ccagtccact gcctttctga caatgtgtgg agtcacgtat gcttggtata tgcctttact    720
acttttaaag ttctacagtt tattacttgc ccaagtgtta ctaaatcctt ttcttatgtg    780
tactggatgg agaaaaaatt atagccagca ctttgagagg aaagttttca gaaacaatat    840
taactggcac tactaactga aggccacagg agatgctatc aatgttattt gtaatctgaa    900
gattgaacaa ggctgtgagg ctcatttcaa actattttga ggtgttaaaa tatatatatg    960
ctgtttctca gctgttccac tcaaaccgtg ttaggactct caaaggtaaa atgtcacagg   1020
ggcttttcag ttgttacaga gctcagcagc tgtggttgcc cctgttctac accaatttca   1080
gttcaataaa aatgttaact ttgcaaaaaa aaaaaaaaaa aaactcga                1128

<210> 613
<211> 495
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (389)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (409)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (428)
<223> n equals a,t,g, or c

<400> 613
caacctgccc ctgatgcctt tccaagttcc agagctgcct gttggcaatg agacaggcct     60
actggccgcg agcagcaaga caagagccct gtgtgagccc ctcccgtact acacctgcag    120
ctgtgtcctg ggcttcatcg cctgctcggt cttcctgagg atgagcctgg agccaaaggt    180
tgtgctgctg acagtggccc tggtggccta cctggtgctc ttcaacctct ccccatgctg    240
gcagtgggac tgctgcggcc aaggcctggg caacctcacc aagcccaacg gcaccaccag    300
tggcacccct agctgttcct ggaaggacct gaagaccatg accaatttct acctggtcct    360
gttctacatt caccctgctt tacactctnc cagacagatt ggactattna tggccgcttg    420
ggantgcnta tggaagaaga atttcaagaa ggagcacgag gagttttgag accatggaga    480
acgtggaaac cgctt                                                     495

<210> 614
<211> 2652
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<400> 614
gggactgcct ggccgtgggn cagaggggtt tgcccttctc ggagggtacc tcctgttccc     60
tgtctgagca tcctgcatgg aagtcaaagg aaatcccttt cttggtgacg acttaaatct    120
gggttccctc agacattggg ttgcacccca acaaatatta aatggcttct tcttaaagcc    180
cagagaaaga ggttttttaa aagactgtcg ccaaatagct gagccaaaag gctgatcaga    240
attcactttt tggaatgtgg cagttaaaca ctaccttgat cattctctcc tctttcctcg    300
aggaactcct ggagggtttg agcgtctgga aactctctgc tctgacccga ggaagcaccc    360
tcctgacgcc gccttcctcc ggttattgaa aggacgcctc agaaatgctt tgttttcttt    420
tacgatgtat tcagaagcct ttactgatta aagttttctt ttatttgggt ggccgggaga    480
gacccaggga ggttctggag gttcctttct gtctcctggc cccaccaggg atttccccat    540
ttctgtttgc tgcctgaaag caggatgagg aaggccaagg agagtccttg cacccgtgag    600
cgtcaggatg aggaaatgac aggaggaaga cgtgggtttg ggttagtggc tgctggcgtt    660
ttggcccttg gtgtttctgg agcctccagg gatctagggg agcctgggct gcgtgcatgt    720
cgataagcag agctgttctt ggggagaagg agggaggtct cgggagtgta gcaccatgcc    780
aaccagccct gcgcgaagac agagtgagcc acgcccggat ggcagggcat gtttctgttt    840
tggtgtctca ctttcctccc agcgtgactt atttggggat tcctcagggc ctactggaat    900
gtgactgccc actgcccagc tgcctcgggt acaagtcctg gccctatgtc ccagctgtca    960
ggggctcagg gaatcctacc cagccacctg tcctgggatg gagtgtcagc atccacccct   1020
tggttgtcat cgaggccgcc ctcccagtcc tgggtgaaga tatttgggcc accagggctc   1080
ccttggcccc ttcacgtagg aaatagacac gtgcttttta atgcaggaca ctttgagtgt   1140
tacaaaatct gtagacctgg cagtagggtc atgatgttgg gaagggtgta gtgccctagg   1200
ttggtgacag aagggacaga cacttgtgca caggtgtctt tggtgatggg gttttttttt   1260
ttataactta gtaaaaaaaa aaaaatgtat gtggaattct gtctcttggt aaagctcaaa   1320
gccaggctag cctgaggtgg cgcagggctc tccttcctgt cccttcgatc tccttgagaa   1380
ttaagagctg gcagctgctg atggtgtttc ccaacccccc tcacttccca agacaacccc   1440
cagcttcagg tcctcatggg gaggggaggg cacgttcttg ayacatggga acttcgctca   1500
ggagggcctc cccttcccct ctccctcaga gttttcactg ccgtctcgtc tttagaaagc   1560
tgtttgaatt ccccccgccc ccagtttgga ccgtgtagat ataactggat atacggattt   1620
ttctctttgt gcaggcttct tatgccgttg gtatacaggg caggaaagag aggaataaag   1680
ggagagagca gtgtggaaac cacggtggtt ttgctttgtt cttactaggt tttggtgcca   1740
ccttccctgc ctgcgcttgt gccccctctc ctccttggca ctggcggcct ccttgcctcc   1800
cttccaccag tgctgccatc ccgtgcctgt cgtgttggtt cttcacacgt gctctgttct   1860
cggggttgtt ccattcatgc cttcttggag ggtgagggtg gcttgggaac cgacccagtg   1920
atcatgccta ctttcttctt tgtatctccc tccttcccag cccacccggg cagcagactc   1980
tgatggaagg aaggtgccgt agtgggcttt tagaaactaa cgggactggt tttcaaagca   2040
gttatcttgg gaaactgttt attccagcga tgtgactttt ttcagaatat ttcttggaat   2100
catattcaga gtctggggct gtgtgttgag cagccttaag gatgctagac actcatttag   2160
tgcccaggga gtccagcgaa tgacgtctgt ggccaagcga ggtctcaggt gcaaagcaaa   2220
aggaccattt aaagtaaaat agcttggatt caatcatgtg acttttaaat tggctcagaa   2280
agcaattttg taatttcaga gagtgttttg agccatggcc acgttgtcat tgtgagtcta   2340
tagcttgact ccttggagaa caatattcat ttggttgtgg agactgattt gctgggagaa   2400
atctgtcctg ttactttctg gtcatcccag gttctgactt ttaccagggg caaaaaaaaa   2460
aaaaaaaagc aagagggaga taaatcccat ctgtgagttt gtcttattgg cgcctttttc   2520
ctcagctgtc ttccaagtat tatttttact gttaaaaaat tttttaaaaa tgtgaaatgt   2580
aatgttttta cagcaacaat atgaaatata ttttataagg aataaaatgg taccttgtct   2640
gatttaaaaa aa                                                       2652

<210> 615
<211> 636
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (560)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (605)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (631)
<223> n equals a,t,g, or c

<400> 615
ctaacccggc acagtgagcg gagcgcctgg gcggcggcgg cggcggcgtg atggctccgg     60
ccgcggaccg agagggctac tggggcccca cgacctccac gctggactgg tgcgaggaga    120
actactccgt gacctggtac atcgccgagt tctggaatac agtgagtaac ctgatcatga    180
ttatacctcc aatgttcggt gcaattcaga gtgttagaga cggtctggma aaacggtaca    240
ttgcttctta tttagcactc acagtggtag gaatgggatc ctggtgcttc cacatgactc    300
tgaaatatga aatgcagcta ttggatgaac tcccaatgat atacagctgt tgcatatttg    360
tgtactgcat gtttgaatgt ttcaagatca agaactcagt aaactaccat ctgcttttta    420
ccttagttct attcagttta atagtaacca cagtttacct taaggtaaaa gagccaatat    480
tccatcaggt aattttttgt aaattattac acattagatt gtttacgata catggctgct    540
ttgtgatttc cttggctaan aaatgatatg caagataaaa atttttttaa tgaaatggta    600
gatgntctaa ggaaggtcaa gtggttaaaa nggagg                              636

<210> 616
<211> 2326
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2305)
<223> n equals a,t,g, or c

<400> 616
naatattagt aaaccatgat gcagcaactg ctaagngcta aactaacaaa attgtgtcat     60
catagctgct ggcttggtgt gaactcgctt aaaagcaatg gtgaaaggat aacctcgatg    120
atgtaaatcc acccaaagat actgttctac aaaaagtagg gtgtggacgc aaacctgtga    180
cagcagaggg ggacgacttc acactcactg cctcatgtgg cccctttccc agtggcagct    240
ggtgacacta acgattgcta ctcggttcac ttgcccagat gtcttcatat gatgagcaag    300
gccagaagca aggctagatt cgaagtttct gacaccattt ccagtttgca caaaagtcag    360
tattttatct taaagtggct tgatttccaa tagctgaact tgggcagaaa acagcaggcc    420
aatgttccta tgtggtttct ttgttgttgt ttttgtttgg ggtgggggca agtacagggt    480
aattcatgag caagacattt cactgctgtc gaagtctctg ggatcccgct gtgggtctga    540
gatggcctgg gaaggacctt gtggacaatg gttttatctg ttctttttgt cactgttaat    600
ttctgggctg ctgaggttct agaatagaag ggctgccaaa tgaggtttgc tgcaggagga    660
aagtttaatc ccccattcca aaagtccagg ccaaatggtg ggcttagcct ctttgaaaag    720
ttctgccttg cccccacagg tgggcacatc ctgtgtctca ttcaccatga tgcttcctga    780
gggtgttcta gaagcccgtt ccccagtggc tgtatccagc ctttccttgc atcatcttcc    840
tcttgaaggt gaggaagtga aaactacaga cctcccccgg acagcccact ctctatcacg    900
agcctaaccc gcgggaggcg gaagagacat ccattcgaga actgaagcgg cctccgggat    960
gaggtcagag gccccacctg attttcctgg tggtggtatc caaaatcttc agtaactagg   1020
aaggaaacca gggtctcatg gtttaaaaga ctttgaagca ggaatgttgc atttgacgcc   1080
tttaaaacta cctttttgct gttgggagga gtcgggggcg agccttagca gctgcaccgc   1140
catccccatg ctggttggtg ctgccctgcc tctcgtgccg ggtgttgctt cagcccagag   1200
ccagagggct gggtcccggg tcctccacag gtgaccccgg tggacacacg cgttcccatc   1260
ctggcctccg tctctgcttt tccacttcta cctgcgtgtg ggtttgccgc cttgtcatcg   1320
gttgtgtgag tgtcgcagac ctttccagag ctccggttca ctctttccaa acaggcctcc   1380
ctgtcggtgg cactgcactc ctagaacctt cagtttctac gatggtttgt ttggtccttt   1440
tgaaccaccc caaagaactc aacatggcaa agcaaatggt aaaagcttcc cgactgttct   1500
actttgggtc cgcgcgaagc ccactcacgt gtgatctgtg ttgcccctct cggtggtccc   1560
aggcgatcca gccatgcccc ctgcccctct gcccagatgc ttcaggggcc cggcttttca   1620
ggcttgccct caccagcggc cgtcagccga cactcaggga tgtagctaac accactccgc   1680
cagtgctttc agtaggaaga gctgaggctg cctgggaggc ccggggcgac cggaaaaggg   1740
ctctctcaag ttctgaaaag agaatctgcc accagatcga atttcgaccc ctgagcttgt   1800
tcggacgtat ggtccaaatt cagattaagg tggtcaccca acccgagatg tcaggaaagg   1860
ccttctgcag agaaaatgtc cccccacccg ccatctgcag ccaggtgtgt gccacacggc   1920
agccttcccg aaacatagta tggattttaa aaatgtgttt atttttgttt ctcaaccact   1980
ttataacgta ttttttaatt tattttgtaa tgtcttgttt tgaagtattg ctgctatcct   2040
tgttatcctt cccactgttt ttatcactga tttattttgt gaaagttgta cactaatgtt   2100
ctatgtcaaa atcaaaagta tttaatgaaa tactagttct atttaatgtg gttatggaac   2160
cagctggaaa cacaaaacaa acagtgattg tacagcaggc tgggcccagg aggtcaggtt   2220
cattttgtta catatgcaat aaactcacga ctttaaaaaa aaaaaaaaaa aaagggcggc   2280
cgctctagag gatccctcga gggancccaa gcagagcgct tcccgt                  2326

<210> 617
<211> 1477
<212> DNA
<213> Homo sapiens

<400> 617
ttgggtatct ttctactcct aagaaggtat taagaataac ataaaaccta gtgagtttgc     60
aaggcttagc ctccgaaggg tgactaagac aggctttctt ttcctgtctt cagaatgaat    120
ggattacaaa gactagatac aactttaggt tttctttgtc ttcttttttt ttaatttaat    180
ttttattttc tttttctttt tctgtgagcc tatggttgta ttgaaacttt aggttttctt    240
gagctgtggt gctgagggca ggaagaagac actaacagcg aagcatgtgt ttgtggttgt    300
tggaggattc ctgcagttca cttgaggtgg cggaatcttc tggtggaggg atgccctccg    360
gcgtgggtct ggggttgtgt gctcctggtg gtcctagtgg ttttctttgc ctgtggtcca    420
gatactgctg gatactggca gctcctgtgg ttgggccagt ttgtacactt ggcgttaggc    480
ttgatcagtg atgttgctga ccctcgccca tgctgggtaa gtgtccaggt ggaagaggct    540
aactccccag gtgttgatgg ccaccattac tatcaccagt ccaataacgt tgactcccag    600
gccagctttc accatatctt tgatctggca gtgcccatag ctgaagacga tggcattagg    660
gggattgccc acaggcagca tcactgcaaa ggagatgcac atggtgactg ggatcagggt    720
gtagaggggg ttaatgtgca gcgtttcaga caggctgcac aggatgggca ggaagatggt    780
gatggttgct gggttgctca caaactcagt gacaatggac acgaggatgc atgccagcag    840
ggtgacagcc cacggtggga ggctgctcag ggacaacatc tggttcccaa tccatgtaga    900
gaggccagag ctcttgctac cagaagccag agcatagcct cccccaacca gaatgacaat    960
ctcccagggc atggtcttct ggaagtcctt ccacgtgatg atgggctcgg tccccagtga   1020
gtgctcctgg ttctctccat cattcttttt cccaaagcag ggcttcttcg ctggaatgag   1080
gaagaggagg aagccaagga agacagagac tgtggcatca gtacggtagc ctttcttttc   1140
aaagaaagaa tcccagccag ggacaaagcc aggctcccgg gtaaaccaca gtacggtcat   1200
caggatgaag aaaaatccag tcaccatttc tgggtagcta atgtctccca gtttttcata   1260
ttcttcttgg atcctcttct ctgacaactg ttcccttttg gtcttcttct tcttgctcag   1320
agagcaggtc tctttaaaat tgcagcccag gaacagccag tgcatccaga accagctgac   1380
caccagcatg atgagggata tggggaagct gaagaggaac caggtgccaa agttcaccac   1440
ctctgcggct ggatactggt tgttgaagtg ttccagg                            1477

<210> 618
<211> 716
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (625)
<223> n equals a,t,g, or c

<400> 618
ggcacagacc ggacttccgg ctggtctgtg gggtttcggg ttcggggttt cctggtgggc     60
gtcaggggca ggcaacagag tggcggccgc tacggccctg gaacggggcc atggagaagc    120
tgcggcgagt cctgagcggc caggacgacg aggagcaggg cctgactgcg caggtcctgg    180
atgcctcatc ccttagtttc aacaccagat tgaaatggtt tgccatctgc ttcgtatgtg    240
gcgttttctt ttctattctt ggaactggat tgctgtggct tccgggcggc ataaagcttt    300
ttgcagtgtt ttataccctc ggcaatcttg ctgcgttasc agtacatgct ttttaatggg    360
acctgtgaag caactgaaga aaatgtttga agcaacaaga ttgcttgcaa caattgttat    420
gcttttgtgt ttcatattta ccctgtgtgc tgctctttgg tggcataaga agggactggc    480
tgtgttattc tgcatattgc agttcttgtc aatgacctgg tatagcctgt crtacatccc    540
atatgcaagg gatgcagtta ttaaatgctg ttcttctctc ctaagttgaa aatcagaaac    600
ttgtggaaaa gagcacttga atgtnggtac yctatgkttg gtgaagtttg cttttcccca    660
taaaacactc caggaacaac tgacgtgaca gtgaagacgt tttgacaagt cattgt        716

<210> 619
<211> 1108
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1101)
<223> n equals a,t,g, or c

<400> 619
cgccggsagt ggacgccgcc gaggcccgga gtcgcgcctg cagacacagc atctactcag     60
cgtgggtcac ctctgtgaac atcactgact gcaagcctcc ctcaatttct ggtgcagccc    120
atcagggacc cacagcgcct gggaggatgg tgcggatctt ggccaatggg gaaatcgtgc    180
aggaygacga cccccgagtg aggaccacta cccagccacc aagaggtagc attcctcgac    240
agagcttctt caayaggggc catggtgctc ccccaggggg tcctggcccc cgccagcagc    300
aggcaggtgc caggctgggt gctgctcagt cccccttcaa tgacctcaac cggcagctgg    360
tgaacatggg ctttccgcag tggcatctyg gcaaccatgc tgtggagccg gtgacctcca    420
tcctgctcct cttcctgctc atgatgcttg gtgttcgtgg cctcctcctg gttggccttg    480
tctacctggt gtcccacctg agtcagcggt gacctctgag ggctgatagg ggtgggtttg    540
ttgagaggga cttgctgggc cttggtgtga gagcaggcat atttggaggg gatctggtgg    600
tgccttgaag gtatgatcag agaggggacc acaggtgtgt gtttcccctt tgtgttaagc    660
gtgaggcaga gggagacgtt agtccagcat ttccaaagtg tgggtgggtc cgttggttcc    720
cgagatactt ttaggtggta tggggcctgc attaagtggc acaaaatcag agcaagaaag    780
cgatgccctt cccaattctc tcaatccttt tatgccgaga agatctcagc tggatgccaa    840
catgttccga tgcctgtgga agacatgccg acgtctcctc tgcctaggga gcaggacttg    900
ggcttagggc aggtggaaaa aattccagac ttttttagca ctgtttttgt tttaatggta    960
tatttttatt ggctacttta ttgtttagga caagtggtag tggcattcta tttattgtga   1020
ccttttcaat aaatagattt aagtaaaaaa aaaaaaaaaa aaactcgagg gggggcccgg   1080
tacccaattc gcccctatag nagagtcg                                      1108

<210> 620
<211> 2638
<212> DNA
<213> Homo sapiens

<400> 620
tcgacccacg cgtccgctct tcttcttcaa catgctcttc tgggtgattt ccatggtgat     60
ggtggctgtg ggtgtctacg ctcggctaat gaagcatgca gaagcagccc tagcctgcct    120
ggcagtggac cctgccatcc tgctgatcgt ggtgggtgtc ctcatgttcc tgctcacctt    180
ctgtggctgc attgggtccc tccgcgagaa catctgcctc ctgcagacgt tctccctctg    240
cctcaccgct gtgttcctgc tgcagctggc cgctgggatc ctgggcttcg tcttctcaga    300
caaggctcga gggaaagtga gtgagatcat caacaatgcc attgtgcact accgagatga    360
cttggatctg cagaacctca ttgattttgg ccagaaaaag tttagctgct gtggagggat    420
ttcctacaag gactggtctc agaacatgta tttcaactgc tcagaagaca accccagtcg    480
agagcgctgc tctgtgcctt actcctgttg cttgcctact cctgaccagg cagtgatcaa    540
cactatgtgt ggccaaggta tgcaggcctt tgactacttg gaagctagca aagtcatcta    600
caccaatggc tgtattgaca agttggtcaa ctggatacac agcaacctat tcttacttgg    660
tggtgtggct ctaggcctgg ccatccccca gctggtggga attctgctgt cccagatcct    720
agtgaatcag atcaaagatc agatcagcta cagctctaca accagcagca ccgggctgac    780
ccatggtact gagaatccat cctgcacctc ctcaccatgg aaactggcaa gcctcataaa    840
cgaacagcag tgggtgctga aagcagcacc aaatggagat ttggattcca gccccccagt    900
gacagcccag tgggaagaag caaactccag atgggcagaa ggcagggtgc acaggtggct    960
ccagtctcag gaggatgcgc ctcctctccc ccatcccagc cctcagcatt gtgccagagt   1020
gataccctta agtgtttggg tttatgtttt cagttttgtt tgggaaacag cagttgcaca   1080
gagagttggg ggtactgctg ctgccttttc accgaggcac tgccaccacc agctctagca   1140
gggatgctcc tgagcttggc ggacatactt agatcctaac gtgccagtga gacctggctg   1200
tggagagtag cactggcagc cctgcctgga ctccacttgg catgatacca gctccagaag   1260
ggaagggagt ggagcaggca gtgaggagag agcctggggg tcggctgggg acagccgtat   1320
gtgctaggta ggagtggagg gagatatgtt taccaaatgc ctgtcctgcc atcctcccag   1380
gtagtcagag tgagctacat cctgccccgc cttcatttcc atggaaacat ggcagctagg   1440
acacggggta caacagcagc caaattcttc cccacctccc ttacttcgaa aaaaagtttg   1500
gaaccctggt ccctatactc tgcagtcaga agtgggactg agccatacat gcccttgaat   1560
tcctccctgt ctggccctcc ctctccagca agcagggttt tctttaactt ggcagtgtgc   1620
agaggagaag tggtaacacc cccaccccat tcccctgcat cggagctcag tattcctaca   1680
gggtaagagg taggaatctt gctgggacga ggggagccag aagtggcaat aaaagcgtgt   1740
tgacctgggc tacgcgggac tccatgaatt ttccattctg gcaactggaa ggggaggtgt   1800
agaagggccc tgcagaggac ggcactggag actctcctaa acgccacaca cctccccctt   1860
gctgcccgcc acacgcgcgt ctccttcaac cgatgcattg ccaccctccc acagcctcgc   1920
cctctgctct aaattaggtc gaaagagtcc cagttccaat ctaggaacag cataattttg   1980
ttccaaaacc tgatctgtgt ttttctaatt aaaattaatt tgtcacccaa aacaggaggg   2040
ggatggggag gagggacatg agcactccgc tggggccggg acggggaatg aggaggaaga   2100
aggccctctc ttcccctacc cgggccctcc aggaccttct ccctgagtcg gctgtaggga   2160
ggactccgag gaagctcggc gcggtgcgct gggcctcctg gcgccgggag gagcgcgcga   2220
ggcaggcggg gcgggcgcgt ccggggcggg gcgctggact tcgtgggtgg tccccgcccc   2280
cgcggcggcc taggcccgcg cctgcgtccc ccaacccgga ggagatgggg ggctgtgcta   2340
gctgcttgcc cagcgagtgt tcccggagtc tcctcgccgc accccgctat cgggcgctca   2400
gaccaggggc tcggcctggc gggaaatagc ctcgaccgaa ctgctgcggg gacaaagagc   2460
cgcgagttcg ctccctgccc ccagtgtctc ctaagcgagc cttctgctcc taggaaggcg   2520
cctttccagc agccgctggg accctggcca gtgtttagct cccaactagt aacagacgga   2580
aagaaaaaat aaaattatcc agaatctaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa     2638

<210> 621
<211> 1393
<212> DNA
<213> Homo sapiens

<400> 621
gggtcgcggt cattttgagc ccctgtctgg atgacttctt gcggctgttc tacccctccc     60
cctccccgcg gtaccttgca cttttctccc tccctgcccc ctctcgagtc caccctccgg    120
gccttctgcc cctgatcgct tggttttcct tgcagtcgcc tgctgctgtc gtcgggagga    180
aagatgaatg ggagggctga ttttcgagag ccgaatgcag aggttccaag accaattccc    240
cacatagggc ctgattacat tccaacagag gaagaaagga gagtcttcgc agaatgcaat    300
gatgaaagct tctggttcag atctgtgcct ttggctgcaa caagtatgtt gattactcaa    360
ggattaatta gtaaaggaat actttcaagt catcccaaat atggttccat ccctaaactt    420
atacttgctt gtatcatggg atactttgct ggaaaacttt cttatgtgaa aacttgccaa    480
gagaaattca agaaacttga aaattccccc cttggagaag ctttacgatc aggacaagca    540
cgacgatctt caccacctgg gcactattat caaaagtcaa aatatgactc aagtgtgagt    600
ggtcaatcat cttttgtgac atccccagca gcagacaaca tagaaatgct tcctcattat    660
gagccaattc cattcagttc ttctatgaat gaatctgctc ccactggtat tactgatcat    720
attgtccaag gacctgatcc caaccttgaa gaaagtccta aaagaaaaaa tattacatat    780
gaggaattaa ggaataagaa cagagagtca tatgaagtat ctttaacaca aaagactgac    840
ccctcagtca ggcctatgca tgaaagagtg ccaaaaaaag aagtcaaagt aaacaagtat    900
ggagatactt gggatgagtg aaaaattaca tcattggaca tgaaggagtt tcaacatcca    960
gcttcatcta ggtggtcatg attacctgca tgctttgagc tcagcagcag tcttcataaa   1020
cacatttaaa acaagatcct gggtttttgt ggtttgactt ctatggtgtt ttaaaaaaac   1080
acagattttt agtgttaata ttgtgtaaat gtactcacct tagggattca tttgaatgat   1140
ggtattatac catgattgta tacagtttgt gaaattgttg caagggcaaa gataactctt   1200
aaaaaaccgt cgagattaca atgctctaga atcagcatat aagaaaataa atgatatctg   1260
catgttgaat tggggtggat ggggggagca agcataattt ttaagtgtga agctttgcat   1320
caagaaatta ttaaaaagct ttttttctcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1380
aaaaaaaaaa aaa                                                      1393

<210> 622
<211> 1778
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1730)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1747)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1753)
<223> n equals a,t,g, or c

<400> 622
gctgtttact aggcacgact gcgaaggcaa gggggcacca gctcaggact gcatctgcct     60
gccatttccc ttccactcct cctttctgga gtctgacatt agaaagccag cgagaaggaa    120
gattcaaaca accaaccctg atttcctgct tctccttttc atgagtgttc ctgtggtctc    180
tgcacctcct ttctgtcccc cggcagaggg cagtagagat ggccggccca aggcctcrgt    240
ggcgcgacca gctgctgttc atgagcatca tagtcctcgt gattgtggtc atctgcctga    300
tgttatacgc tcttctctgg gaggctggca acctcactga cctgcccaac ctgagaatcg    360
gcttctataa cttctgcctg tggaatgagg acaccagcac cctacagtgt caccagttcc    420
ctgagctgga agccctgggg gtgcctcggg ttggcctggg cctggccagg cttggcgtgt    480
acgggtccct ggtcctcacc ctctttgccc cccagcctct cctcctagcc cagtgcaaca    540
gtgatgagag agcgtggcgg ctggcagtgg gcttcctggc tgtgtcctct gtgctgctgg    600
cmggcggcct gggcctcttc ctctcctatg tgtggaagtg ggtcaggctc tccctcccgg    660
ggcctgggtt tctagctctg ggcagcgccc aggccttact catcctcttg cttatagcca    720
tggctgtgtt ccctctgagg gctgagaggg ctgagagcaa gcttgagagc tgctaaaggc    780
ttacgtgatt gcaagggttc agttccaacc atggtcagag gtggcacatc tgctcagcca    840
tctcatttta cagctaacgc tgatctccag ctccagcgat ggaacccact acagaggagg    900
tggggcccct gtgtcaaaga ggccgagggg cagcaagggc agccagggca cctgtgactt    960
cttagtacaa gattgtctgt ccttcaggac ttccaaggct cccaaagact ccctaaacca   1020
tgcagctcat tgtcacacca attcctgctt taattaatgg atctgagcaa atcttcctct   1080
agcttcagga gggtggggag ggagtgattg ctgtcatggg gccagacttc caggctgatt   1140
tgccaaatgc caaaatgaaa cctagcaaag aacttacggc aacaaacgag gacattaaaa   1200
gagcgagcac ctcagtgtct ctggggacat ggttaaggag cttccactca gcccaccata   1260
gtgagtgggc cgccataagc catcactgga actccaaccc cagaggtcca ggagtgatct   1320
ctgagtgact caacaaagac aggacacatg gggtacaaag acaaggcttg actgcttcaa   1380
agcttccctg gacctgaagc cagacagggc agaggcgtcc gctgacaaat cactcccatg   1440
atgagaccct ggaggactcc aaatcctcgc tgtgaacagg actggacggt tgcgcacaaa   1500
caaacgctgc accctccact tcccaaccca gaacttggaa agacattagc acaacttacg   1560
cattggggaa ttgtgtgtat tttctagcac ttgtgtattg gaaaacctgt atggcagtga   1620
tttattcata tattcctgtc caaagccaca ctgaaaacag aggcagagac atgtaaaaaa   1680
aaaaaaaaaa aactcgaggg ggggcccggt acccaaktcg cccttatagn gagtcggaat   1740
taacaanttc aantgggccg tcgtttttac aacggtcg                           1778

<210> 623
<211> 1176
<212> DNA
<213> Homo sapiens

<400> 623
ctgcctcagc ctcgcctgct cctacgtggg cagcctctac gtctggaaga gcgaactgcc     60
cagggaccat cccgcggtca tcaagcgacg cttcaccagc gtcctggtgg tgtccagtct    120
ctcacccctg tgcgtgctgc tctggaggga actcacaggc atccagccag gcacatccct    180
gctcaccctg atgggcttca ggctggaggg cattttccca gcggcgctgc tgcccctgtt    240
gctgaccatg attcttttcc tgggcccact gatgcagctc tctatggatt gcccttgtga    300
cctggcagat gggctgaagg ttgtcctggc cccccgctcc tgggcccgct gcctcacaga    360
catgcgttgg ctgcggaacc aagtgatcgc cccgctgaca gaggagctgg tgttccgggc    420
ctgtatgctg cccatgttag caccgtgcat gggcctgggc ctgctgtgtt cacctgcccg    480
ctcttttttg gagttgccca ttttcaccat attattgagc agctgcgttt ccgccagagc    540
agcgtgggga acatcttctt gtctgctgcg ttccagttct cctacacagc tgtcttcggt    600
gcctacactg ctttcctctt catccgcaca ggacacctga ttgggccggt tctctgccat    660
tccttctgca attacatggg tttcccagct gtttgcgcgg ccttggagca cccacagagg    720
cggcccctgc tggcaggcta tgccmtgggt gtgggactct tcctgcttct gctccagccc    780
ctcacggacc ccaagctcta cggcagcctt cccctttgtg tgcttttgga gcgggcaggg    840
gactcagagg ctcccctgtg ctcctgacct atgytcctgg atacgctatg aactctsacc    900
gtctccccag ccctccccac caaggggtac tgcaggggaa gggctggctg gggtccccga    960
gatctcagga atttttgtag gggattgaag ccagagctag ttgcgtccca gggaccaaga   1020
gaaagaagca gatatccaaa gggtgctcgg ggttttttat ttataaaacc tctccccacc   1080
ccccaccccc caacttcctg ggttttctca ttgtcttttt gcatcagtac tttgtattgg   1140
gatattaaag agatttaact tgggtaaaaa aaaaaa                             1176

<210> 624
<211> 983
<212> DNA
<213> Homo sapiens

<400> 624
ggcacgaggt tttctttatg gagtacttct ttcctccgcc tttcctctgt tttcctcttc     60
ctgtctcccc tccctcccac ctttttcttt ccttcccaat tccttgcact ctaaccagtt    120
cttggatgca tcttcttcct tccctttcct cttgctgttt ccttcctgtg ttgttttgtt    180
gcccacatcc tgttttcacc cctgagctgt ttctcttttt cttttctttc tttttttttt    240
tttttttaag acggattctc actctgtggc ccaggctgga gcgcagtggt gcgatctcga    300
ctcactgcaa cccccgcctc ctgggttcaa gcgattctcc tgccccagcc tcccaagtag    360
ctgggaggac aggtgtgagc tgccgcaccc agcctgtttc tctttttcca ctcttctttt    420
ttctcatctc ttttctgggt tgcctgtcgg ctttcttatc tgcctgtttt gcaagcacct    480
tctcctgtgt ccttgggagc cctgagactt ctttctctcc ttgcctccac ccacctccaa    540
aggtgctgag ctcacatcca caccccttgc agccgtccat gccacagccc cccaaggggc    600
cccattgcca aagcattgct gcttctcttc accccatgga ggctatgtca ccctaactat    660
cctggaatgt gttgagaggg attctgaatg atcaatatag cttggtgaga cagtgccgag    720
atagatagcc atgtctgcct tgggcacggg agagggaagt ggcagcatgc atgctgtttc    780
ttggcctttt ctgttagaat acttggtgct ttccaacaca ctttcacatg tgttgtaact    840
tgtttgatcc acccccttcc ctgaaaatcc tgggaggttt tattgctgcc atttaacaca    900
gagggcaata gaggttctga aaggtctgtg tcttgtcaaa acaagtaaac ggtggaacta    960
cgactaaaaa aaaaaaaaaa aaa                                            983

<210> 625
<211> 2338
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<400> 625
gcccacgcgt ccgggccnat tcgtgtaatt attgcccatt tggctcattc cccaagcccc     60
taattcattt taattcattt taaacaaaag cagagtacac cggtattgct ccagatcgct    120
cacatcacct gggacagtcc catggcccct atgagtcaac tcacagcttg cggggagtgg    180
gccttctcct ggccttgttc ttgctcataa acaggtcact tcctccatga agagaccagt    240
ttccacgctc ccatctctca ctgctgactc agcgatgcct ctgcctcggt ctgcttttga    300
agactgtgac cttcaccagg aggttttact tacaccagtc gggaagatta gtccctcatt    360
ctgcctggag tgccccgtgt ttgacttggc agcgggtgtg gagccatccc cgcgtcctcc    420
tggcrcattg ccactgtggc tgtccaggaa caggatgtgg ctgccttggc cgaatgttgt    480
cctactctcc ccaaccycgg cgcctcagct cctcagctcc tcgggcccct gcgtctggct    540
ggtgtttgca gggctttcgc tctgctctgg tattgctctg cctttataga aagtcttatt    600
gaagaagtgt aagaaagacc taaggtgggg aagactccta cacacaccat tagtatcagt    660
gacaccagca atgtaggttc ccagcccctt cccagtggca gcttgtgtgt ccaggagata    720
ggacatcatt taacgcatca gcaaagtagc agcagatgcc acatacagag tagagcgaag    780
gcatttggtg gatcggtcac tagagatcta tcttgcagaa agtatgtttt tcctcataaa    840
agtgcctctt aattggccat tgtaccagcc acttgtccta gccaaatgtc caaaacacgc    900
ccttgggccc cgccacgtta caatccacag attgtctgtc tgagtcgttt aaggcatttc    960
ctggtgcttg tgttccatga ataaaaggac aaagtcagaa gatcactgat gtcttactgt   1020
caacagagat attttaaaag agagaagcag gaaaagatct tccttttttg atctacaact   1080
tatatagttt tctgattatg cacataatag atatgccttc cagatgcata aggcaaacat   1140
ctggaaagaa atatacccaa atcttagcag gggttatctt tgggagtgga gtacatggga   1200
ttttgctttc ttcattttta taattttata ttactgtctt ggaagatgtg tttatgtgtg   1260
tgtgttactt ttacaatcag gaaaacatat ttaataacat atagtcaaga aaacagactt   1320
aaaaataaat actatgtgtc cattgagaaa attcacaata taaacagaaa tacaaataaa   1380
tacatacaca attttaaagt cacctgtagc cctaccctta gaggtaccca gggttaacat   1440
tttggtggta ttgtcttatc aatttttccg ttgatacatt cagcaaattt ggagcacatt   1500
gaccatggag ttttgtgtcc aaatccaatc tgaatttacc tggaagaggc cttgacacct   1560
gcatggaaat gagctaagaa aaccactgga gccttgggag ctctttggcc tcctggctgg   1620
cccagtaata tctgagctcc tttggttaat ttataactga tataaaacta catcttcttt   1680
ataatataaa ttgtacctgt gagtctagaa gctttaaatg tgtttaaatt aaaatattca   1740
agctaaatgt tactgctctc tcccaaattc tgtaagtttg actcccgtta ccccaattag   1800
aagtaacttc tttgtttcat gccactttta tagcatttgg taattctgct ataacacatc   1860
ttgcccctat tattaactgt gcacagctac acaaaggtgt gccttctacg tgggaacatg   1920
gattgtgaat gactctgtaa tgaggcctga gtcttagtta tctttccact cactccccgt   1980
ctcccctttc caaccccaaa ggctcacgat aggggctcac taaatgtcag tgtttcacca   2040
aagtattttt tccattgtat taagagtcca gtcactgtat atggaagtat tttatttttt   2100
atttttttat atcacttgag tccactagta gtacttcctt gctctgtttg acttgtcaga   2160
tacaaagaca cgggattaga ttttgggtgg taaaattgtg atacgcatgg ctgttgatgg   2220
agtggaacat cttagtgatg tgagaaaggt cattttagtt ataaatgtaa accaattact   2280
ttagcacaac aataaagatg ttctggaaat tattataaaa aaaaaaaaaa aaaaaaaa     2338

<210> 626
<211> 564
<212> DNA
<213> Homo sapiens

<400> 626
aagaaaggat ttatgtgctt gggattcttg aggggttttc cagagtcagt ccccaattct     60
gatgttttta tacgcaacac taggggtcct tctgaagtta tcccggcccc tgggaaactc    120
acgtggcatg gggccccctt ctgccctggt ctctttcatc ccatctgtcc cggccccaga    180
gcctgtccag tctggtcctc tctgtcctgc ttggtttgtc accatgtgat gttgggatgg    240
cttgtctttg ccgcctcact tcctaagctg acagacgtgt ctgctaggga ccatcagctc    300
ccaagccgca tgacggtgct ttccttcaag gttcagaggc ttccctttca gtctggccca    360
tctcccacat cctaatggct ctgctgtctc aggggcagct ctccttttta acttattggc    420
agagctggga tgacttatag gtccctggct cagtgagtaa gcaagttcag agacttggct    480
ttggccattt tgttctctta ggctcatcct tggatgccaa cagggaaatt acctgccaga    540
tttcagtcac tactttttag aagt                                           564

<210> 627
<211> 1324
<212> DNA
<213> Homo sapiens

<400> 627
ccggcttgtg catgatgacg gccggcctgg tgatgaacac cattcatcct ggccatggtc     60
atcagcagtt tcggaggact catcttgagc aaaaccgttt ctaaacagca gtacaaaggc    120
atggcgatat ttacccccgt catatgtggt gttggtggca atctggtggc cattcagacc    180
agccgaatct caacctacct gcacatgtgg agtgcacctg gcgtcctgcc cctccagatg    240
aagaaattct ggcccaaccc gtgttctact ttctgcacgt cagaaatcaa ttccatgtca    300
gctcgagtcc tgctcttgct ggtggtccca ggccatctga ttttcttcta catcatctac    360
ctggtggagg gtcagtcagt cataaacagc cagacctttg tggtgctcta cctgctggca    420
ggcctgatcc aggtgacaat cctgctgtac ctggcagaag tgatggttcg gctgacttgg    480
caccaggccc tggatcctga caaccactgc atcccctacc ttacagggct gggggacctg    540
ctcggtactg gcctcctggc actctgcttt ttcactgact ggctactgaa gagcaaggca    600
gagctgggtg gcatctcaga actggcatct ggacctccct aactgggccc cgctggtccc    660
atttgctcat tagaatttcc tctcacatca gtgggataca gaattcagtt tctcccttgc    720
caggtccttg ggatggttga cccctgcctc tgcagtagcc ttttgtgagt ctgctaaggt    780
agctctcaca cacctcggct ctggggttga tacctgagcc tgcaatagag ccctgaaatc    840
aagagcatgg cttgagtgtg tgaatatgat gtgtgcacat gcttaatgag cgtgcaagtg    900
tgcacacgtt tgtggagagg agggtgttct ggcctgagaa ggtaaagaag aggcatgtcc    960
agtatgcttt gcagggtgtg tttgctcttt tccatgccca tgcaacccag attggggtgg   1020
agcaggaagg agctcttttc tgttcccaag cctcagaact cttgagctgt ggcttacttg   1080
ctgtcttcac caggttcaag ctccgtgggc cacactgctg ctgtgccaag aaggtgtaca   1140
gcctccccag gatggggcct catacaaccc ttcatctgca ctcaacattt aatcgtgtcc   1200
ttgctgtctt tttattttcc tttttgtttg ttagcaaaaa cctctattta gatttcaata   1260
atcagagaag tgtaaaataa aacagattat attgtaaaaa aaaaaaaaaa aaaaccggca   1320
cgag                                                                1324

<210> 628
<211> 1626
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (60)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1600)
<223> n equals a,t,g, or c

<400> 628
nccaccccat acccccacca ccctactacc ccagcttcct gccctacttc ctctcgatgn     60
atgtcaatgt caccaacagc aatggggccc accatmagcy tggacctgga cgtggatgat    120
gtggagatgg agaactatga ggccctcctg aacctggccg agcggctggg agatgccaag    180
ccccggggtc tcaccaaagc agacatagag cagctcccgt cgtaccgctt taacccggac    240
agccatcagt cggagcagac gctgtgtgtg gtctgcttca gtgacttcga ggcgcggcac    300
tgctccgagt cctcccctgc aaccatgagt tccacaccaa gtgtgttgac aagtggttga    360
aggccaaccg gacgtgtccc atctgccggg ccgacgcctc cgaggtgccc agggaggctg    420
agtgaggcca cgcagccgcc tgcccgggag aaccctgcct gaagctctgg aaacttgtgg    480
gtggggccca gggaggatgg ggagggagtg gcccaggcct gccccttcgc tcctgcctgc    540
atttccagag ctggtgccag ggtcagccca gcgaggagtc cctgcaataa gcccctgcat    600
ttgccaagct ccaaagactc cctccctagt ctgcctgccc gcccgcccgc cacggagctg    660
cctgagtgtc cctgatcggg tctccctcct gtgcaccctc aggtccctcc ttttcctgct    720
ggcactgagt gccaggggtc cgctccctca gtggggccgg tggagatcct tggccccagg    780
atgggcagac agagcaccat cctgggtcag aaggtctcat sctctgaaat ggcgtgccct    840
ctgcccaggt ggcactgcca ggtgcgtaga cagacggtgt cacgagccat ttcctgagcc    900
ccagggctga atcccccctc cttgaccccg aacagtgaac tcaggcagct ggctctgtgt    960
tggctgctgt gagggctgag tctggttccc taggggaccc tcatcccagg aacaacattc   1020
cagccccacc ctcaggctgg agggcgtccc agcctaatcc cgagctgggg cacacgtatc   1080
ctgaggggct tkggccatac ggggagaggg agccctgtgt tcccggtggt tgtccctccc   1140
agggatgcag ccagacccgt gcccaatctc ctctccctct gttgttttgc atgaacgtga   1200
ggagcagcag tttttgttca ttcatttggc ccaaaatcac gtgtaggatt tggggatgtg   1260
gatatttaag acaatttctt ttttcttttg gtttaatagg ggcgggtata gggaccaact   1320
gggaccgagt gcccaggggg ccgagcacgg tcatgctggc cggcctgcat gcatgcgtgt   1380
gccgggctgg gctgggcggc cggcggtcgt ggggcagggt tgggggtctg tgctcagctg   1440
ataactgcca tgcactgtac tgcacacgtc cctagagcct accgggaccc gacgcttttc   1500
arggcatttc tccctccagc carggcccaa ctcccacctg yctkgggcga atctcctccc   1560
aaagaaattc cccagaaaga attgggaacc agaaaaggtn tttgaacccc catcttccca   1620
gggggc                                                              1626

<210> 629
<211> 1083
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (27)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (32)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (111)
<223> n equals a,t,g, or c

<400> 629
aaggcagcca cacctnagta atgaagnata antaacaccc taaaactttg cccgaaactg     60
tatattgtag ccatacttaa accccatgca aggaaaaaat tggcaaattg naaaattcct    120
ccccattaaa gattgatatt tttgcaaact aacaaattta acgatttcgg tacccctccc    180
caaaaatgca gtcacataaa atatatcaat actattttga attagctcta gaaatcacac    240
tgaaactatg ttacatttac aaatattaaa tttattataa ctaaaatgaa tttaattgtt    300
ctcagatttg gccaccttat agctccgttt aaggagggga tttgttaaaa acaaaaatgc    360
attataactt ggtcaaatta ctttcacatt aaggaaaaaa acttctaaaa aggaaaacaa    420
gaaaagcaac tcttcagttt cacataatta aaagaacagg agaaagcacg caagctacat    480
atagctaaat ttacgaaacc aaccaaagcc agggggattt ctcttctgat tatgtgtcat    540
aaaaaggtcc actgtcttat atacacatgt atataatgtt acattccatc actgtaaaaa    600
gtcccctttg ccccctcccc caaaaaagtt tcagtctagt ctccaaactt ggaaagcggc    660
gctcgctcct gctgccggtg cagttcgttc tcggtcagca gctggaggtt ctcggcgcgc    720
agccggtcca gctccagctc cagctcccgc acacgcgcgt cgtcgccacc cagccgcttg    780
ctctccagcc gcagccggtt gttctcgtcc tccatgcgcg agaggcactt ctccagttcc    840
aggtactcct tgatgagctc ctgcttgctc atgttctgca ggctctccgt gtggtaccgc    900
tcgtacgtct ccgagaagtc ccgctgcaga aactcgctgc cgtcccctcc catcccatcg    960
ctgcccccat cctcctcacc cccttcttcc atgaagtcgt catcgctggt gtcgtcggat   1020
ttgcggcggs ccgyttggag tamaggccgg ttttgaggtc cggctcctcc tggtcgtgat   1080
cat                                                                 1083

<210> 630
<211> 1817
<212> DNA
<213> Homo sapiens

<400> 630
gtctggttct atcatgactt atgtaattga tacatattat caaatattta attgtgggat     60
gttgaactat tcaaaattac cacattaatg atacgtaatc ttatgtatat tctgtgagcc    120
accacgcccg gccgatttgg ggcattttta tttaacagaa cttctctaay cttccaactg    180
cttcccacaa acacattggc ctcaaggctc cttagaatcc cagttccagc ttcctaaaat    240
agacagtggg tatcgggcag cagtcactgg ggctcaaggg cagtgagcaa gagaaatgtc    300
taaagctgct tctcccaaca ccgtccaaag tctccactgc ctgagttttg tttcggctgg    360
tttgaactca tttcgggtgt gtgcattttt cttttggtac ccatgtgaga catgaacaac    420
aggagggagg gaaagagccc aggtgggacg tgggacaggc ttaggggaaa gagcttgtcc    480
tatctcagga acaaaattat aggctgtggg cagagggtct gaaaggtggg ctttggggta    540
gtgcccaagc ctggtcgtgt tgccaggagt ggtgacaaga aatgcagctt acatcaaacg    600
aacatgtagt gcatgcccac tgcctgatgg ccagatggct gtaggaagag ctaccagggc    660
ttccagacct gtggaacgaa gaggatgggg aaaaggcaga gggcactgag tgtcccttta    720
aaaactaaca cactgaatat tccgtgtgat ctagaacagt gtggcagctt tcacagcaca    780
ggaccgttca tcgggggcct aaacgtttcc ctcrgctctg tcaccaactc acttctctcg    840
gcttcgttgt ctgtaaattg gatgaaaaga gctctaatgc ctttcaggct cttagaagcc    900
atagatttgg acaagcccag caagatgggt gtccttccag gcctcttccc ctttcctcca    960
tctctggcaa cagttcttgg ggtttggcaa ttgtttggat tttttttctt tctgcagttg   1020
tgtgtatgtg tgtttgtgtg aagaaaaaca gactctgtcc aggtagaaat ggtgaggagg   1080
gggaagagaa ttacatttcc agggtcagaa acttggcaac agttttccta gagtgactca   1140
gacacaccac agtaacaact ctcgctgcaa ttttatttta atttgagaaa taaagatttc   1200
ctccaagcca catgaggact ctggcaccca cccacaaagc aagacctgta tttataagcc   1260
gagggctcag ggagcctaac tgcgggaccc gtcaggcccc gtgacccatc cccgtcccca   1320
cccccccctc caccgctggg cccatcagtg tgtgttgggg ggatgcttgg cagctggggg   1380
tgaggagaca acaaacctcg ggaactggag ccagagctgc ggcctgactg acgccttttg   1440
atgctcacgg gaaatttctg cccaggatct cagccccagg ctggttgttt ctacaaatct   1500
ctctcaaatg tattattttg gtgacaaaaa tgaaggagct ttgtaaattt ttttaaaatt   1560
atgaatcata tcaagtagtt gtttacattt cttgaaaaaa taggaactcg ggcagcagaa   1620
tcagattggc agaatcttta gactacacag gcaataatca agtctgctgt tttggccttt   1680
cgtagtagaa gtggttgtag tgtttagata tctgtttggt cttgcttctt gtattgcatt   1740
tttttcaata aacaacaaca aaaagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1800
aaaaaaaaaa aaaaaaa                                                  1817

<210> 631
<211> 1887
<212> DNA
<213> Homo sapiens

<400> 631
gaattcggca cgaggcggtg cggggcctgg gcgggagccg ggaggcgcgg ccggcatgga     60
ggcgctgctg ctgggcgcgg ggttgctgct gggcgcttac gtgcttgtct actacaacct    120
ggtgaaggcc ccgccgtgcg gcggcatggg caacctgcgg ggccgcacgg ccgtggtcac    180
gggcgccaac agcggcatcg gaaagatgac ggcgctggag ctggcgcgcc ggggagcgcg    240
cgtggtgctg gcctgccgca gccaggagcg cggggaggcg gctgccttcg acctccgcca    300
ggagagtggg aacaatgagg tcatcttcat ggccttggac ttggccagtc tggcctcggt    360
gcgggccttt gccactgcct ttctgagctc tgagccacgg ttggacatcc tcatccacaa    420
tgccggtatc agttcctgtg gccggacccg tgaggcgttt aacctgctgc ttcgggtgaa    480
ccatatcggt ccctttctgc tgacacatct gctgctgcct tgcctgaagg catgtgcccc    540
tagccgcgtg gtggtggtag cctcagctgc ccactgtcgg ggacgtcttg acttcaaacg    600
cctggaccgc ccagtggtgg gctggcggca ggagctgcgg gcatatgctg acactaagct    660
ggctaatgta ctgtttgccc gggagctcgc caaccagctt gaggccactg gcgtcacctg    720
ctatgcagcc cacccagggc ctgtgaactc ggagctgttc ctgcgccatg ttcctggatg    780
gctgcgccca cttttgcgcc cattggcttg gctggtgctc cgggcaccaa gagggggtgc    840
ccagacaccc ctgtattgtg ctctacaaga gggcatcgag cccctcagtg ggagatattt    900
tgccaactgc catgtggaag aggtgcctcc agctgcccga gacgaccggg cagcccatcg    960
gctatgggag gccagcaaga ggctggcagg gcttgggcct ggggaggatg ctgaacccga   1020
tgaagacccc cagtctgagg actcagaggc cccatcttct ctaagcaccc cccaccctga   1080
ggagcccaca gtttctcaac cttaccccag ccctcagagc tcaccagatt tgtctaagat   1140
gacgcaccga attcaggcta aagttgagcc tgagatccag ctctcctaac cctcaggcca   1200
ggatgcttgc catggcactt catggtcctt gaaaacctcg gatgtgtgcg aggccatgcc   1260
ctggacactg acgggtttgt gatcttgacc tccgtggtta ctttctgggg ccccaagctg   1320
tgccctggac atctcttttc ctggttgaag gaataatggg tgattatttc ttcctgagag   1380
tgacagtaac cccagatgga gagatagggg tatgctagac actgtgcttc tcggaaattt   1440
ggatgtagta ttttcaggcc ccacccttat tgattctgat cagctctgga gcagaggcag   1500
ggagtttgca atgtgatgca ctgccaacat tgagaattag tgaactgatc cctttgcaac   1560
cgtctagcta ggtagttaaa ttacccccat gttaatgaag cggaattagg ctcccgagct   1620
aagggactcg cctagggtct cacagtgagt aggaggaggg cctgggatct gaacccaagg   1680
gtctgaggcc agggccgact gccgtaagat gggtgctgag aagtgagtca gggcagggca   1740
gctggtatcg aggtgcccca tgggagtaag gggacgcctt ccgggcggat gcagggctgg   1800
ggtcatctgt atctgaagcc cctcggaata aagcgcgttg accgccaaaa aaaaaaaaaa   1860
aaaaaaaaaa aaaaaaaaaa actcgag                                       1887

<210> 632
<211> 2394
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2004)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2017)
<223> n equals a,t,g, or c

<400> 632
cggaagcgct ggacgagagg aggaattact ctagggtaca aggcctcgcc caggagtggg     60
gggttgcttc cgggtcgcgc tcccggaaac aggaagttgc ccatcctcct cgcccggcgg    120
cagctgtccc cgaggcggga ggagcccgag ggggcgcgag cccgcatgga ttttatattg    180
gaagacatgg atcttgctgc caacgagatc agcatttatg acaaactttc agagactgtt    240
gatttggtga gacagaccgg ccatcagtgt ggcatgtcag agaaggcaat tgaaaaattt    300
atcagacagc tgctggaaaa gaatgaacct cagagacccc ccccgcagta tcctctcctt    360
atagttgtgt ataaggttct cgcaaccttg ggattaatct tgctcactgc ctactttgtg    420
attcaacctt tcagcccatt agcacctgag ccagtgcttt ctggagctca cacctggcgc    480
tcactcatcc atcacattag gctgatgtcc ttgcccattg ccaagaagta catgtcagaa    540
aataagggag ttcctctgca tgggggtgat gaagacagac cctttccaga ctttgacccc    600
tggtggacaa acgactgtga gcagaatgag tcagagccca ttcctgccaa ctgcactggc    660
tgtgcccaga aacacctgaa ggtgatgctc ctggaagacg ccccaaggaa atttgagagg    720
ctccatccac tggtgatcaa gacgggaaag cccctgttgg aggaagagat tcagcatttt    780
ttgtgccagt accctgaggc gacagaaggc ttctctgaag ggtttttcgc caagtggtgg    840
cgctgctttc ctgagcggtg gttcccattt ccttatccat ggaggagacc tctgaacaga    900
tcacaaatgt tacgtgagct ttttcctgtt ttcactcacc tgccatttcc aaaagatgcc    960
tctttaaaca agtgctcctt tcttcaccca gaacctgttg tggggagtaa gatgcataag   1020
atgcctgacc tatttatcat tggcagcggt gaggccatgt tgcagctcat ccctcccttc   1080
cagtgccgaa gacattgtca gtctgtggcc atgccaatag agccagggga tatcggctat   1140
gtcgacacca cccactggaa ggtctacgtt atagccagag gggtccagcc tttggtcatc   1200
tgcgatggaa ccgctttctc agaactgtag gaaatagaac tgtgcacagg aacagcttcc   1260
agagccgaaa accaggttga aaggggaaaa ataaaaacaa aaacgatgaa actgctttct   1320
gggggttggt tacttagtta cctgcccttt gcatgcatgt gtgaaccagc tgtgagctgc   1380
aaggcagtgg gccagagcct cgccctcctg actcttcctg caggtggctc aggaaggatt   1440
cagcctggcc acttggctag gactctgcca gcacccatct gagactgacc tcttccgggc   1500
ctttggacac tatgaccttg atgctgccct tcaggcagga aacagggctg gtgccttttt   1560
tcacctgcat ggccagcttc cttccctggc agtggagagg gcagccaaca ggttctaatg   1620
tcagagccat cctttaccag gtgggcctgc ttgtccctgt cttgcctgcc acatcactct   1680
actttttgga aggccatggc tgattaaaga agttcttgta gtttcccaag caaagtggaa   1740
tctagaaaca gtgaaaaaag ttcagataac tttgaattgc attcaagaag tacacttctt   1800
tcccattgtc cgtggctctt ggagtctccg tgatgccagg ctagagtctg attatataat   1860
aattcaaaat ggtaactccc aaggtaatgc tttcttccat ttcatcaggt tcttttatcc   1920
ccactgcacc ccctcccctt ctcccttgcc tatctggatg gcttctcaga agctcggccc   1980
tagtcctccc tgccttggcg gggnccagag cccactnact gctgaggcag cactgctctc   2040
gtcagctgtg ttgcctttac caagtgtctt cagagggtta tgagttagag tagctggcct   2100
ggggagaggg tgcctccctg ggtttgatct ttagggtctg actttctgca gagaagatgt   2160
tttacagatg tgtcaaagct gatgtaatgt ggttggggga ggaaatccag acccaaagtg   2220
tttgtcagct gggtgtacaa ctgcctatgt gatcctctgt cttaaaatga tttctgtctg   2280
tgctgcgaaa caaagacaag gtgaggtgtt tttctttttt gtaataatat aaagctgtgt   2340
gtttctgatt ggatgattca ctatgtgcat tgttccycct aagtgctttt agta         2394

<210> 633
<211> 766
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (91)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (141)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (652)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (753)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (763)
<223> n equals a,t,g, or c

<400> 633
gaagttaggc aacatgcctt ataaggagag aaaaagcacc gtgcatgccg attggnggga     60
gtaagggtgg tatgatcgtg gtatgatcgt ncccttgtta ggaaggcaac agacgggtct    120
aacacggatt ggacgaacca ntgaattccg cattgcagag atattgtatt taagtgccca    180
gctcgataca ataaacgcca tttgaccatt caccacattg gtgtgcacct gggttgggat    240
ctgccatcat ggaggcgggc ggctttctgg actcgctcat ttacggagca tgcgtggtct    300
tcacccttgg catgttctcc gccggcctct cggacctcag gcacatgcga atgacccgga    360
gtgtggacaa cgtccagttc ctgccctttc tcaccacgga agtcaacaac ctgggctggc    420
tgagttatgg ggctttgaag ggagacggga tcctcatcgt cgtcaacaca gtgggtgctg    480
cgcttcagac cctgtatatc ttggcatatc tgcattactg ccctcggaag gctaaggtga    540
ttcaaactaa atcaacccaa tgtctctcct acccactcac cattgctacc cttctcacct    600
ctgcctcctg gtgcctctat gggtttcgac tcagagatcc ctatatcatg gngtccaact    660
ttccaggaat cgtcaccagc tttatccgct tctggctttt ctggaagtac ccccaggagc    720
aagacaggaa ctactggctc ctgcaaacct gangctgctc atntga                   766

<210> 634
<211> 3004
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (86)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2898)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2971)
<223> n equals a,t,g, or c

<400> 634
aactacttcc gcgggaaaga acgcgcaggc acttggcctt gtgggcgctc acttgccccg     60
gaagtactgt tgagttagcg cctcgncttc cggggcggat tgtctgtcgt tgcagtagct    120
gtaggaaggg gaggccattt tccgtttctg ggaggagtga ggggcaacgg gtcggagaaa    180
aaggaaaaaa gaagggctca gcgcctcccc gccgggccgt ggacagaggg gcacagtttc    240
ggcaggcggg tgaggtcgct gagggcccgc cggagatgtt ttccttgtcg agcacggtgc    300
aaccccaggt tacagttcct ctgagtcatc tcatcaatgc cttccataca ccaaaaaaca    360
cttctgtttc tctcagtgga gtgtcagttt ctcaaaacca gcatcgagat gtagttcctg    420
agcatgaggc tcccagcagt gagccttcac ttaacttaag ggaccttgga ttatctgaay    480
taaaaattgg acagattgat cagctggtag aaaatctact tcctggattt tgtaaaggca    540
aaaacatttc ttcccattgg catacatccc atgtctctgc acaatccttc tttgaaaata    600
aatatggtaa cttagatata tttagtacat tacgttcctc ttgcttgtat cgacatcatt    660
caagagctct tcaaagcatt tgttcagatc ttcagtactg gccagttttc atacagtctc    720
ggggttttaa aactttgaaa tcaaggacac gacgtctcca gtctacctcc gagagattag    780
ctgaaacaca gaatatagcg ccatcattcg tgaaggggtt tcttttgcgg gacagaggat    840
cagatgttga gagtttggac aaactcatga aaaccaaaaa tatacctgaa gctcaccaag    900
atgcatttaa aactggtttt gcggaaggtt ttctgaaagc tcaagcactc acacaaaaaa    960
ccaatgattc cctaaggcga acccgtctga ttctcttcgt tctgctgcta ttcggcattt   1020
atggacttct aaaaaaccca tttttatctg tccgcttccg gacaacaaca gggcttgatt   1080
ctgcagtaga tcctgtccag atgaaaaatg tcacctttga acatgttaaa ggggtggagg   1140
aagctaaaca agaattacag gaagttgttg aattcttgaa aaatccacaa aaatttacta   1200
ttcttggagg taaacttcca aaaggaattc ttttagttgg acccccaggg actggaaaga   1260
cacttcttgc ccgagctgtg gcgggagaag ctgatgttcc tttttattat gcttctggat   1320
ccgaatttga tgagatgttt gtgggtgtgg gagccagccg tatcagaaat ctttttaggg   1380
aagcaaaggc gaatgctcct tgtgttatat ttattgatga attagattct gttggtggga   1440
agagaattga atctccaatg catccatatt caaggcagac cataaatcaa cttcttgctg   1500
aaatggatgg ttttaaaccc aatgaaggag ttatcataat aggagccaca aacttcccag   1560
aggcattaga taatgcctta atacgtcctg gtcgttttga catgcaagtt acagttccaa   1620
ggccagatgt aaaaggtcga acagaaattt tgaaatggta tctcaataaa ataaagtttg   1680
atcaatccgt tgatccagaa attatagctc gaggtactgt tggcttttcc ggagcagagt   1740
tggagaatct tgtgaaccag gctgcattaa aagcagctgt tgatggaaaa gaaatggtta   1800
ccatgaagga gctggagttt tccaaagaca aaattctaat ggggcctgaa agaagaagtg   1860
tggaaattga taacaaaaac aaaaccatca cagcatatca tgaatctggt catgccatta   1920
ttgcatatta cacaaaagat gcaatgccta tcaacaaagc tacaatcatg ccacgggggc   1980
caacacttgg acatgtgtcc ctgttacctg agaatgacag atggaatgaa actagagccc   2040
agctgcttgc acaaatggat gttagtatgg gaggaagagt ggcagaggag cttatatttg   2100
gaaccgacca tattacaaca ggtgcttcca gtgattttga taatgccact aaaatagcaa   2160
agcggatggt taccaaattt ggaatgagtg aaaagcttgg agttatgacc tacagtgata   2220
cagggaaact aagtccagaa acccaatctg ccatcgaaca agaaataaga atccttctaa   2280
gggactcata tgaacgagca aaacatatct tgaaaactca tgcaaaggag cataagaatc   2340
tcgcagaagc tttattgacc tatgagactt tggatgccaa agagattcaa attgttcttg   2400
aggggaaaaa gttggaagtg agatgataac tctcttgata tggatgcttg ctggttttat   2460
tgcaagaata taagtagcat tgcagtagtc tacttttaca acgctttccc ctcattcttg   2520
atgtggtgta attgaagggt gtgaaatgct ttgtcaatca tttgtcacat ttatccagtt   2580
tgggttattc tcattatgac acctattgca aattagcatc ccatggcaaa tatattttga   2640
aaaaataaag aactatcagg attgaaaaca gctcttttga ggaatgtcaa ttagttatta   2700
agttgaaagt aattaatgat tttatgtttg gttactctac tagatttgat aaaaattgtg   2760
cctttagcct tctatataca tcagtggaaa cttaagatgc agtaattatg ttccagattg   2820
accatgaata aaatattttt taatctaaat gtagagaagt tgggattaaa agcagtctcg   2880
gaaacacaga gccagggnat atagcctttt ggcmtgggtg ccwgggcttc acatctgtaa   2940
tcccagcact tttgggaggc tgaggccggt ngggttgctt gagggccggg ggtttcgaga   3000
cccg                                                                3004

<210> 635
<211> 517
<212> DNA
<213> Homo sapiens

<400> 635
gctaggtggc agcggaccaa gctgacccgg cgagcggacc ggggctggag agcggcgacc     60
actgcggatc tcggaaggaa gaaatgatgt aaatcactca tccaaacttt aaggtcaaag    120
gtgagaagga aggtcaggaa gaacatggcc tggccaaatg tttttcaaag agggtctctg    180
ctgtcccagt tcagccatca tcatgttgta gtgttcctgc tcactttctt cagttattcg    240
ttgctccatg cttcacgaaa aacatttagc aatgtcaaag tcagtatctc tgagcagtgg    300
accccaagtg cttttaacac gtcagttgag ctgcctctgg agatctggag cagcaaccat    360
ttgttcccca gtgcagagaa agcgactctt ttcctcggca cactggatac cattttcctc    420
ttctcctatg ctgtgggcct attcatcagt ggcatcgttg gggatcggtt gaatttgcga    480
tgggttctgt cttttggcat gtgctcttct gcattaa                             517

<210> 636
<211> 2695
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (65)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (356)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2685)
<223> n equals a,t,g, or c

<400> 636
tgggtctctc acggatctcg gcctgagggt gtgggggaga aggcctggac agcctcaggg     60
caggntgtgt tttcccacca gccgcagaga gccaggatgg acgttcctcg gacggacggt    120
tttcctgctt gggaatgttc ctgggctgtg agatccactc ttctgggcag gtggttagca    180
cctaacgttt ttccctcact tccccccaaa ttcttaagtc ctttggtcca tttcactgct    240
cggaccttga gacaacagtc attctgcctg agtctgtctt cagagagacg ccccccgtgg    300
tcaggcccgc agccccggag aggcccagga gccagaggag ctggcacggc gacagngacg    360
gcacccggag ytgagccagg gtgaggytgt ggccagcgtc atcatctacc gyaccctggc    420
cgggytaytg cctcataayt wtgaccytga caagcgcakc ttgagagtcc ccaaacgccc    480
gwtcatcaac acacccgtgg tgagcatcag cgtccatgat gatgaggagc ttctgccccg    540
ggccctggac aaacccgtca cggtgcagtt ccgcctgctg gagacagagg agcggaccaa    600
gcccatctgt gtcttctgga accattcaat cctggtcagt ggcacaggtg gctggtcggc    660
cagaggctgt gaagtcgtct tccgcaatga gagccacgtc agctgccagt tcaaccacat    720
gacgagcttc gctgtgctca tggacgtttc tcggcgggag aatggggaga tcctgccact    780
gaagacactg acatacgtgg ctctaggtgt cgccttggct gcccttctgc tcaccttctt    840
cttcctcact ctcttgcgta tcctgcgctc caaccaacac ggcatccgac gtaacctgac    900
agctgccctg ggcctggctc agctggtctt cctcctggga atcaaccagg ctgacctccc    960
ttttgsctgc acagtcattg ccatcctgct gcacttcctg tacctctgca ccttttcctg   1020
ggctctgctg gaggccttgc acctgtaccg ggcactcact gaggtgcgcg atgtcaacac   1080
cggccccatg cgcttctact acatgctggg ctggggcgtg cctgccttca tcacagggct   1140
agccgtgggc ctggaccccg agggctacgg gaaccctgac ttctgctggc tctccatcta   1200
tgacacgctc atctggagtt ttggtggccc ggtggccttt gccgtctcga tgagtgtctt   1260
cctgtacatc ctggcggccc gggcctcctg tgctgcccag cggcagggct ttgagaagaa   1320
aggtcctgtc tcgggcctgc agccctcctt cgccgtcctc ctgctgctga gcgccacgtg   1380
gctgctggca ctgctctctg tcaacagaga caccctcctc ttccactacc tctttgstac   1440
ctgcaattgc atccagggcc ccttcatctt cctctcctat gtggtgctta gcaaggaggt   1500
ccggaaagca ctcaagcttg cctgcagccg caagcccagc cctgaccctg ctctgaccac   1560
caagtccacc ctgacctcgt cctacaactg ccccagcccc tacgcagatg ggcggctgta   1620
ccagccctac ggagactcgg ccggctctct gcacagcacc agtcgctcgg gcaagagtca   1680
gcccagctac atccccttct tgctgaggga ggagtccgca ctgaaccctg gccaagggcc   1740
ccctggcctg ggggatccag gcagcctgtt cctggaaggt caagaccagc agcatgatcc   1800
tgacacggac tccgacagtg acctgtcctt agaagacgac cagagtggct cctatgcctc   1860
tacccactca tcagacagtg aggaggaaga agaggaggag gaagaggagg ccgccttccc   1920
tggagagcag ggctgggata gcctgctggg gcctggagca gagagactgc ccctgcacag   1980
tactcccaag gatgggggcc cagggcctgg caaggccccc tggccaggag actttgggac   2040
cacagcaaaa gagagtagtg gcaacggggc ccctgaggag cggctgcggg agaatggaga   2100
tgccctgtct cgagaggggt ccctaggccc ccttccaggc tcttctgccc agcctcacaa   2160
aggcatcctt aagaagaagt gtctgcccac catcagcgag aagagcagcc tcctgcggct   2220
ccccctggag caatgcacag ggtcttcccg gggctcctcc gctagtgagg gcagccgggg   2280
cgkcccccct ccccgcccac cgccccggca gagcctccag gagcagctga acggggtcat   2340
gcccatcgcc atgagcatca aggcaggcac ggtggatgag gactcgtcag gctccgaatt   2400
tctcttcttt aacttcctgc attaaccctg ggccgtggtt cctamgcccg aggctccctt   2460
cccttcccca gccgcactca tgccctgctc ctgtcttgtg ctttatcctg ccccgctccc   2520
catcgcctgc cgcagcagcg acgaaacgtc catctgagga gcctgggcct tgccgggagg   2580
ggtactcacc ccacctaagg ccatctagtg ccaactcccc ccccaccatt cccctcactg   2640
cactttggac ccctggggcc aacatctcca agacaaagtt tttgnagaaa aaaaa        2695

<210> 637
<211> 1579
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1529)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1556)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1569)
<223> n equals a,t,g, or c

<400> 637
ggcagaggga acccacgcgg aggaaggaag agacgcaggc aggctgcggt tacccaagcg     60
gccacccggg cctcagggac cccttccccg agagacggca ccatgaccca gggaaagctc    120
tccgtggcta acaaggcccc tgggaccgag gggcagcagc aggtgcatgg cgagaagaag    180
gaggctccag cagtgccctc agccccaccc tcctatgagg aagccacctc tggggagggg    240
atgaaggcag gggccttccc cccagccccc acagcggtgc ctctccaccc tagctgggcc    300
tatgtggacc ccagcagcag ctccagctat gacaacggtt tccccaccgg agaccatgag    360
ctcttcacca ctttcagctg ggatgaccag aaagttcgtc gagtctttgt cagaaaggtc    420
tacaccatcc tgctgattca gctgctggtg accttggctg tcgtggctct ctttactttc    480
tgtgaccctg tcaaggacta tgtccaggcc aacccaggct ggtactgggc atcctatgct    540
gtgttctttg caacctacct gaccctggct tgctgttctg gacccaggag gcatttcccc    600
tgggaacctg attctcctga ccgtctttac cctgtccatg gcctacctca ctgggatgct    660
gtccagctac tacaacacca cctccgtgct gctgtgcctg ggcatcacgg cccttgtctg    720
cctctcagtc accgtcttca gcttccagac caagttcgac ttcacctcct gccagggcgt    780
gctcttcgtg cttctcatga ctcttttctt cagcggactc atcctggcca tcctcctacc    840
cttccaatat gtgccctggc tccatgcagt ttatgcagca ctgggagcgg gtgtatttac    900
attgttcctg gcacttgaca cccagttgct gatgggtaac cgacgccact cgctgagccc    960
tgaggagtat atttttggag ccctcaacat ttacctagac atcatctata tcttcacctt   1020
cttcctgcag ctttttggca ctaaccgaga atgaggagcc ctccctgccc caccgtcctc   1080
cagagaatgc gcccctcctg gttccctgtc cctcccctgc gctcctgcga gaccagatat   1140
aaaactagct gccaacccag cctgtggcca ggtcactgtc taccccagcc cagcccagcc   1200
ctctgccgct tgtacatacg ccatggggac cctgaggaac tgaggccacg tcaatccctg   1260
tgccgcccca ttcgcccgtt acatcttcca aactgggacg gtcaaggctg aaggctcctc   1320
tgggtttgag ggtccaaggg acaaggagga gaagcctagc aggatttcag atgcaggaga   1380
gagacccagg aagcccggca gagcctgagc cccaytgcaa ttyctyctag ggstgcacaw   1440
tcatgtggcy ttagggcama ytgtyctgca tccagtctgt gtyctyctgt ctttctcatc   1500
caggtcaggc attgacattt gtaagaaang gggtaaggga cacagctggg caagtngatt   1560
ggttggcang attgctgtc                                                1579

<210> 638
<211> 1334
<212> DNA
<213> Homo sapiens

<400> 638
ggcacgagcg gcaatgaggt cagtgactgc cgggagtcct gcaggggcgg ggcggcgcca     60
agcgcaggga gcccggctga gtggcagccc agattgaaga tggatacgtg acaatcccag    120
ggaccgctgc actgacttca tttccttaga caagacacag tgtagggccc ggcccgtgtt    180
ggccccagga ctcctttgga atatagctgt ggacaatgaa tcctgcgagc gatgggggca    240
catcagagag catttttgac ctggactatg catcctgggg gatccgctcc acgctgatgg    300
tcgctggctt tgtcttctac ttgggcgtct ttgtggtctg ccaccagctg tcctcttccc    360
tgaatgccac ttaccgttct ttggtggcca gagagaaggt cttctgggac ctggcggcca    420
cgcgtgcagt ctttggtgtt cagagcacag ccgcaggctg tgggctctgc tgggggaccc    480
tgtgctgcat gccgacaagg cgcgtggcca gcagaactgg tgctggtttc acatcacgac    540
agcaacggga ttcttttgct ttgaaaatgt tgcagtccac ctgtccaact tgatcttccg    600
gacatttgac ttgtttctgg ttatccacca tctctttgcc tttcttgggt ttcttggctg    660
cttggtcaat ctccaagctg gccactatct agctatgacc acgttgctcc tggagatgag    720
cacgcccttt acctgcgttt cctggatgct cttaaaggcg ggctggtccg agtctctgtt    780
ttggaagctc aaccagtggc tgatgattca catgtttcac tgccgcatgg ttctaaccta    840
ccacatgtgg tgggtgtgtt tctggcactg ggacggcctg gtcagcagcc tgtatctgcc    900
tcatttgaca ctgttccttg tcggactggc tctgcttacg ctaatcatta atccatattg    960
gacccataag aagactcagc agcttctcaa tccggtggac tggaacttcg cacagccaga   1020
agccaagagc aggccagaag gcaacgggca gctgctgcgg aagaagaggc catagctgct   1080
ccagccgggg ctccggggcg gcagcagagc tggcacaccg attctgggaa gccccgcgaa   1140
tgatggcttt tgaattaatg aggcagtgaa tgttttgtgt ttacttctaa gggaaatact   1200
aactttcttt cgcattagta ttaattttga agtagctaca aagtattttt aagaaattat   1260
aattttatga ctgtcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1320
aaaagggcgg ccgc                                                     1334

<210> 639
<211> 633
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (395)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (536)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (545)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (554)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (581)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (620)
<223> n equals a,t,g, or c

<400> 639
ggcagctcgg cagcatggcg tccgtgacgc tgagcgaggc ggagaaggtg tacatcgtgc     60
atggcgtcca gttcagccag tgctacccct gaatttgaag gtagaggagg tgatgacctt    120
ggcaccgaga tcgctaacac cctctatcgg atatttaaca ataaaagcag tgtcgactta    180
aagaccctct gcattagtcc tcgggagcac tgctgsgttc tctatgtgga tgtgctgctt    240
ctggaatgtg gtggaaattt gtttgatgcc atttccattg ctgtaaaggc tgctctcttc    300
aatacaaggw taccaagggt tcgagttttg grggwtgaag agggktcgaa ggmcattgaa    360
ttktcagatg acccttatga ctgcatacga ctaantgtgg agaatgtccc ctgcattgtc    420
actctgtgca agattgctat cggcatgtgg tggatgctac tcttcaggag gaggcctgct    480
cgctggccag cttgctggtg tccggtgacc agcaagggag ttgcgacgtg catgangaaa    540
gtggngaaag gcancctgga cccagagagc atcttcgaga ngatggagac tggcaagcgt    600
gtggcaaggt actggatgcn ttccttgcaa aag                                 633

<210> 640
<211> 2523
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1248)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2514)
<223> n equals a,t,g, or c

<400> 640
gaggcgccgg cttcggagtg cgcccgccgc cgcagcagca gcgctcctgg aggaccccgc     60
cgtcccccgg cwcascgctg cccttcctgc tgctgagcta cccgagcggc ggcggcggca    120
gagcggcagg gcaagcacca tcctaattat ctcatggcta atgaacgcat gaacctcatg    180
aacatggcca agctgagtat caagggcttg attgaatcag ctctgaacct ggggaggact    240
cttgactctg actatgcacc tctccagcaa ttctttgtgg tgatggagca ctgtctgaaa    300
catggcttga aagctaaaaa aacttttctc ggacaaaata aatccttctg ggggcctcta    360
gaactggtag aaaagcttgt tccagaagcc gcagagataa cagcaagtgt taaagatctt    420
ccaggactta agacaccagt aggtagagga agagcctggc ttcgtttggc attaatgcaa    480
aagaaacttt cagaatatat gaaagctttg atcaataaga aagaacttct cagtgaattc    540
tacgaaccca atgccctcat gatggaagaa gaaggagcca taattgctgg tctgttggtg    600
ggtctgaatg tcattgatgc caatttctgt atgaaaggag aagacttgga ctctcaggtt    660
ggagttatag atttttcaat gtatctcaag gacgggaaca gcagtaaagg tactgaagga    720
gacggtcaga ttactgcaat tctggaccag aagaactatg tagaagaact gaacagacat    780
ttgaatgcta ctgtaaacaa ccttcaggca aaagtagatg cattagaaaa atccaacact    840
aaactgacag aggagcttgc agttgcaaac aacaggatca ttaccttaca agaagaaatg    900
gaacgagtta aagaggaaag ttcctacata ctggaatcca atcggaaggg tcccaagcaa    960
gacagaactg cagaagggca agcactaagt gaagcaagaa agcatttaaa agaagagaca   1020
caattacgat tggatgttga gaaagaactg gagatgcaga tcagcatgag gcaggagatg   1080
gaattggcta tgaagatgct ggagaaggat gtctgtgaga agcaggtgcc ctggtatctc   1140
ttcgggcagc agctggatga cctcagagct ctcaagcatg aacttgcctt taagctgcag   1200
agttcagact taggagtwaa acmgaaaagt gaactaaaca gtcgcttngg aagagaagac   1260
taatcagatg gctgctacca ttaaacaact tgaacaaagr ttgcgccagg ctgacgargc   1320
cgccaatctg ctgagttgga caaccggctc ttcaaacagg actttggaga caagatcaac   1380
agtctgcagc tggaagtcga ggagctcacc aggcagcgga accagcttga gttagaacta   1440
aaacaggaaa aagaaagaag attacaaaac gacaggagca tcccaggaag gggttcccag   1500
aagtcagaat ccaagatgga tgggaagcac aaaatgcaag aggaaaatgt taaactaaaa   1560
aagcccctgg aagaaagcca caggctgcaa ccccacccta tggatgaaca ggatcagctg   1620
ctgctctctg aaaagccaca gttgtgtcag ctatgccagg aagacggcag cctaacaaag   1680
aatgtgtgta agaactgcag cggaaccttc tgtgatgcct gttcaacaaa tgaactgcct   1740
cttccttcaa gtatcaagct tgagcgagtt tgcaatccct gtcacaagca tctgatgaag   1800
caatattcta ccagcccatc ataagactgg aggccaagac ctggaccaaa acgtttatgc   1860
aggctcctct gtacctgtgt tttagctgtc aggatctcat agagcccagt tcttagagtc   1920
aactaaagag ttgataggra tttactaggt ccagggagaa aaggcagtgg ttggggttac   1980
tggaaatttt gctcattttc tctaatgact gtatgaataa aagtgaactt acttgagcct   2040
ttctcttcta aatctaaaca acctgatatt gaaggtttgc tttatagcat atctttggaa   2100
aggcaactca tttttatgat tagtgatact ggggtggatt taataggaga gagaatccag   2160
gcagataaga ataaaaagga aaatgatcat ctccttctat agcatttgca gattcaaggg   2220
ggagaggtag atgctgagat caaaatgaca gttgttactt atttttccag gtgctgttag   2280
tataaacatt gtttcctctt cacccctgct aactacctct ttaaagtatt tctaccaaac   2340
tgtgaaccca atctcaggga aaagaaatta aaaagtaata taaattctgc atatattaaa   2400
aacaatattg taatatgtta taatttcagg accagaattt tctggtcttt acctacaagg   2460
gttttcatta tcaaaaaaaa gaacattagg ttttctactt tatgacttca aagnaaataa   2520
ctg                                                                 2523

<210> 641
<211> 605
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (599)
<223> n equals a,t,g, or c

<400> 641
gcttcagctt ccccacctgt ccagggggag gccagtgact gattttagaa ccctttaagc     60
attgaagttc tctgatcctt aaatcactca agtttaatgg ggaaaaagtc acctccattg    120
taattcctga gaactaagtt gggaggtgct ggtgaaacca agcttcgaaa ggttaatcag    180
accaaggacc aacgctagtg tgagttgtga gggatggaca ctggtgaagc tccaggctag    240
ggtgggccaa gggaggcagg cctgccaatg acccatcttc tcccccgcct tccccagcac    300
atgttttacg tgggtcagga ttcaagccgc tgcgtggytt gcatggtgga ctccagcctg    360
ggtgtgtggg tgacattgaa aggtagtgcc cacgtgtgtc tctaccatcc agacaccttt    420
gagcagctgg cagaagtaga cgtcactcct cccgtgcaca ggatgctggc aggctcggat    480
gccatcatcc ggcagcacaa ggctgcctgt ctgcgaatca cagcgctgct ggtgtgtgag    540
gagctgytgt gggtgggcac carwgctggt gtcgtctcac catgcccact tcgtccggna    600
ctgta                                                                605

<210> 642
<211> 444
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (434)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (436)
<223> n equals a,t,g, or c

<400> 642
acatcagaca tcaccatcac ctcgcttaga atccatgggg ccttctcctc aaattcaatc     60
ttcccaggca tttcatgaac ttgcgtctag tttctgttcc ctctcaaatt gcccaggctg    120
tcctgtgagt gacagcagct atttcgtggg cctcctctgg aatcatgaga agtcacccaa    180
acaatctcag ttttctagct cactccgtct tgacatttct acactgtcat ccttggtttt    240
cttggaaatt aatttgcttt tcttcattgt ctttctttgg agctgctttc cttttgttgg    300
ttactatttt atttttagct tctcacacca taccgacata tgttggttat tcttttagac    360
atgttttttg ttgttgttgt cacctggaac ttttgtatct tgaataaatt tggggatcaa    420
atacaaaaaa aaananagga gaga                                           444

<210> 643
<211> 1483
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1409)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1417)
<223> n equals a,t,g, or c

<400> 643
caaagntgnn caggaaaaga gggcaagtgg ctggtgctgt ggacagagaa gctttatttt     60
tagtatgaga caacctctat tttctttcag gagagggaag ttggattatc aattcttttg    120
taaatgtgta tggtgatatt tgctccgctt tttgcaatct ttgcatttgc aacatgcggt    180
ggctattctg gaggcctgcg gctgagtgtg gactgcgtca acaagacaga aagtaacctc    240
agcatcgaca tagcgtttgc ctacccattc aggttgcacc aggtgacgtt tgaggtgccc    300
acctgcgagg gaaaggaacg gcagaagctg gcattgattg gtgactcctc gtcttcagca    360
gagttcttcg tcactgttgc tgtcttcgcc ttcctctact ctttggctgc cactgtcgtt    420
tacattttct tccagaacaa ataccgggaa aacaaccggg gcccactcat tgacttcatt    480
gtcactgtag tcttttcgtt cttgtggttg gtgggttcat cagcttgggc aaaaggactg    540
tctgacgtca aagttgcaac ggatcccaag gaagtattgc tactaatgtc agcttgsaaa    600
caggccatcc aacaaatgca tgggctatcc acagccctgt tatgtcaagc ttaaacactt    660
ctgtggtctt tggattcttg aactttattc tctgggctgg aaacatatgg tttgttttca    720
aggagaccgg ctggcattct tcgggacaga gatatctttc agatccaatg gagaagcact    780
ccagcagcta taatcaaggt ggttacaacc aagacagcta tggatcaagc agtgggtaca    840
gtcagcaggc gagtttgggg ccaacctcag atgagtttgg ccaacagcct actggcccca    900
cttcctttac caatcagatt taacagagta gcatttgcat tcttctgcag tsgcctcacc    960
atcttccatt tcagtggcag aagaattttt taagggtttc aatcaattat taatgcagag   1020
agtattgaat gtaaatcaga gctctctagt cttcattaag gcagcaagtc ctgggttgtg   1080
aaaaatgata cttagagatg aggcgacatg aggagatata ttattcatca tagatggcta   1140
attggagagt accttgttat atatacagat actttcatgg tcattttgta tgtatgttaa   1200
agtagtagaa gtattttgta gcttaaagtc tctagtatgt aatatggcat aaagtaaatc   1260
aaatagcgtt gagttttctt atgcattttg atgtgaaaga tgttataata atttctagaa   1320
gacaatttgg tgtatcacaa catgcatgtc ttattttttt ttagttttaa gtcctatagg   1380
actatgagtc tctaagttaa ttgtttcana aaattantcc ttttttatgt gataaatcat   1440
atgattaaag tgcatgaata gcaattccca aaaaaatgga caa                     1483

<210> 644
<211> 677
<212> DNA
<213> Homo sapiens

<400> 644
tgttgtccaa cttctcccgg agcagccgga gagcaggcgt cgggacgcag caaagagagg     60
agaggccacc atggcggagc tgcaggaggt gcagatcaca gaggagaagc cactgttgcc    120
aggacagacg cctgaggcgg ccaaggaggc tgagttagct gcccgaatcc tcctggacca    180
gggacagact cactctgtgg agacaccata cggctctgtc actttcactg tctatggcac    240
ccccaaaccc aaacgcccag cgatccttac ctaccacgat gtgggactca actataaatc    300
ttgcttccag ccactgtttc agttcgagga catgcaggaa atcattcaga actttgtgcg    360
ggttcatgtg gatgcccctg gaatggaaga gggagcccct gtgttccctt tgggatatca    420
gtacccatct ctggaccagc ttgcagacat gatcccttgc gtcctgcagt acctaaattt    480
ctctacaata attggagttg gtgttggagc tggagcctac atcctggcga gatatgctct    540
taaccacscg gacactgttg aaggtcttgt cctcatcaac attgatccca atgccaaggg    600
ttggatggat tgggcagccc acaagctaac agggctcacc tcttccattc cggagatgat    660
ccttggacat cttttca                                                   677

<210> 645
<211> 2171
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1066)
<223> n equals a,t,g, or c

<400> 645
cgcctgccgg gccggcgggc ggtngtgatt gatccgcgtt ccctggagct ggaggctcgg     60
gggaaagggc cagcacggag cgggcgctcg gttgctgcgc acaaaggctg aggctccaag    120
agctgcaggg cgtgtttggg accccagagt cagaaggagt gagaaccctg acccctaatc    180
ccactgcatc cagccaatag gagcccagcc accatggcgg agctgcagga ggtgcagatc    240
acagaggaga agccactgtt gccaggacag acgcctgagg cggccaagac tcactctgtg    300
gagacaccat acggctctgt cactttcact gtctatggca cccccaaacc caaacgccca    360
gcgatcctta cctaccacga tgtgggactc aactataaat cttgcttcca gccactgttt    420
cagttcgagg acatgcagga aatcattcag aactttgtgc gggttcatgt ggatgcccct    480
ggaatggaag agggagcccc tgtgttccct ttgggatatc agtacccatc tctggaccag    540
cttgcagaca tgatcccttg cgtcctgcag tacctaaatt tctctacaat aattggagtt    600
ggtgttggag ctggagccta catcctggcg agatatgctc ttaaccaccc ggacactgtt    660
gaaggtcttg tcctcatcaa cattgatccc aatgccaagg gttggatgga ttgggcagcc    720
cacaagctaa caggcctcac ctcttccatt ccggagatga tccttggaca tcttttcagc    780
caggaagagc tctctggaaa ttctgagttg atacaaaagt acagaaatat cattacacat    840
gcacccaacc tggataacat tgaattgtac tggaacagct acaacaaccg ccgagacctg    900
aactttgagc gtggaggtga tatcaccctc aggtgtcctg tgatgctggt ggtaggagac    960
caagcacctc atgaagatgc agtggtggaa tgtaactcaa aactggaccc cacccagacc   1020
tcgttcctca agatggctga ctccggaggt cagccccagc tgactncagc caggcaagct   1080
gaccgaggcc ttcaagtact tcctgcaagg catgggctac atggcctcat cctgcatgac   1140
tcgcctgtcc cggtctcgta cagcctctct gaccagtgca gcatccgttg atggcaaccg   1200
gtcccgctct cgcaccctgt cccagagcag cgagtctgga actctttctt cggggccccc   1260
ggggcacacc atggaggtct cctgttgaat ggcccttgtt gccctagagt gggacccagc   1320
cctcacctcc cccagagcta acctgggagg tgctgaaggg gcattgggcc accgtaagca   1380
agggaaaaag ggcagatcat gcggggagat gaccttgatc tttgattgct accctaacct   1440
tgacctttaa cccgtgattc cccccagctc ctggaagaga tgtcctaata tctcttaggg   1500
acccagaccc ctaaattctc ctcctccccc attttgrtgt taaggtggag agggcatatg   1560
catcctctgt cctgatctag gtgtctatag ctgaggggta agaggttgtt gtagttgtcc   1620
tggtgcctcc atcagactct ccctacttgt cccatatttg caaggggagg ggatttgggg   1680
ctggggctcc attcaccaaa gctgaggtgg cttctcatta accctttagg actctgaagg   1740
gtatggacct acgtgaatgt gtgtcagggg gagacttgct ggtgggttag tggtcctcag   1800
gatgtgatag aaacatccag tgtaaaaagg aagttggaat gggagttggc gggcagtgaa   1860
cgagtgtggg gaaggattgg tgctggggca acaggaaggg gcctggggcc gtttggctgc   1920
actaactttg gtagctcagt gtgcatctag agtgggactg gggagggagc taagcttggg   1980
ctgggctgct tggggcttgg catagggtgg aaagggctac cctggggctc tgaccacact   2040
gtagtatgtg tggagggtgc cctcccgtct cccacaactt ctgctataac aataaactgt   2100
agaggaatct gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa acccgggggg   2160
gggcccggga c                                                        2171

<210> 646
<211> 2956
<212> DNA
<213> Homo sapiens

<400> 646
tgggaccgct gtgtagtagg gggctacctc tctccaaaga cagtcgcaga tacatttgag     60
aaggtagtgg ctggctccat caattggcca gccatagggt ccctcttgga ctatgtgatm    120
cgcccggccc cacccccaga agccctcaca ctggaggtgc agtatgagcg tgacaaacat    180
ctcttcattg acttcctgcc atcagtgacc ctcggtgaca cagtcttggt ggccaaacca    240
caccggctag cccagtatga caacctgtgg cggctgagcc tgcgtcccgc ggagacggca    300
cgcctgcggg ctctggacca ggctgactcg ggctgccgat ctctgtgcct caagatcctc    360
aaggccatat gcaagtccac cccggctctg ggccacctca ctgccagcca gctaaccaat    420
gtcatcctcc acttggccca ggaggaggct gactggtctc cggatatgct ggccgaccgt    480
ttcctgcagg ccttgagggg acttatcagc tacttagagg ctggagtcct gcccagtgcc    540
ctaaacccca aggtgaactt atttgcagag ctcacccctg aagaaataga cgaattagga    600
tacactctgt attgctcatt gtctgagcca gaggtgctgc tgcagacgta gggcaggtga    660
aggccaaagc gggtgttggt ggtcaggccc tggattctcc gttagataca cttggctacc    720
tagttggtgc ctcacagggt tcctgctgcc tggtgtcttg ctgatcatca ccctggtcac    780
ttcatgctga ttagaatgac atctctttcg tctcctattt tgttacccaa ctcttcctat    840
ttttgttacc aatcactgtg ctctctgccg ccccctggct ccaggctaat ttttctggaa    900
tgaattgaga aggtggcgtg ctggcctgag ctgatggacc acttggtgtt ttgcgttttg    960
gcccatgttt gctgcctcta tctggtctgc cttgcccgtt tgcctgttcc tattcagtgt   1020
cttttctatt ttttcctctc tcgttcatgc cttctgtttt gctcttgtcc ctggagcata   1080
tctgcctaat taagatgttg ccttttagtt gaatgccact gaagagctgt gatagcatgt   1140
ttcaaagctg aactctacag agcgagtgct gagacagtat ttagggtttc tgggagtgag   1200
gctggtagaa gagttggcct ttgaccacgg ttcctggagt agaagtccat cctcccccca   1260
acctcctgac ccattcataa atgctgagaa tgtctctcat gggaacactg ttaatgaccc   1320
acacaggata agctgaatgc aaagttattt gcaggttgaa tttcttggtg gctattagca   1380
gaagtgcaga gtagggaacc agagctggtt aagggcctag tgaagggttt gtgtgcccag   1440
tgtctgctcg tcatctgtgg ctgcaggggt cagacagaca aggatgggga ctgccagggc   1500
accacttcat catgaatgct ggttttcaca ccttttcctt attttattgc caatcaggac   1560
aaggccttga aggaacgcag ccttagacat caggtgagga tgatggaggt agacagtcga   1620
ctgaatgtca gctggaaaat ccagtcacta gttggggttt ggtggccatg ttttctaccc   1680
agacaggccc tgcttttcta ggatgtggcc ttagagcaag aacagaccca acagccagcc   1740
cttcatcctc cagcgtctgc cataggaatg tgagaggggt gtttgctgag cgctccgggc   1800
acggccagag ggcaagtgag catgcacgga cctcttcccc ctgtcctgtt tctcacccag   1860
cacctgggga gatcggtgct accaaggaag agagcacaca gataagacag aggggaggag   1920
gtgggcattt cctacattcc tccttgtttg ccgctgctga gattgcagta tttattgcaa   1980
tgtaaatgta tcctgaaggt ggggaggaat gtttaatcta ccatgtccgt gtgtcatctt   2040
ggtttgtgtt tttccctgtt tgtagcaaga ctctgatgat aattctgttt ctcatctgcc   2100
cattcagtat tttgttttcc ttccgtcaag ttgtcttatt ttttcaatga ctacctctcc   2160
atcattgagg ttctggtgaa gctctctgca gctgtctcat tccttcccaa cgatagtaac   2220
aggaaatgac tctttagcat cgatacctca acatcaattt agggtagaga ttcctgcccc   2280
tcttttgtca cagattagga aattgagaac tagggttaac cttgactata tttagaggtc   2340
tttttgcctc ttttcccctt aacaaggatt tcttatggtg gtttcagttt catttgcata   2400
aaggtattga gagggaacaa aaaacataaa gctgagaatc ttgagagagc tcatctaccc   2460
tgtctgttgg tcagactcaa atgagagtta aaaaaaaaaa aaaaaatctk tatgcctgag   2520
taccatcctg gatgaatcta gaaggtatgg ggtagagctt gacagggttc ctgtgtaccc   2580
actgggtatc cgttagaggt aagggagagg agaggattga tagagtgttg caaaagtata   2640
gattattcat tgagataaag gatttggttt ccctgccatg agtattaaaa aaatttaagt   2700
tttcccaagc ttgcatctct gaccaaattt cacataaaac attggaagga ggctgggtgc   2760
ggtggctcat gcttgtaatc ccagcactgg gaagctaagg cgggtggwtc acttgaggtc   2820
aggagttcga gaccagcctg gccaacatgg tgaaaccccg tctccacgaa aaagataaaa   2880
ataagctggg cgtggtggca ggcgcctata atcccagcta ctcgggaggc tgaggcagga   2940
gaataactta aacccg                                                   2956

<210> 647
<211> 940
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (399)
<223> n equals a,t,g, or c

<400> 647
ggaacatgga gcgggggccg gtggtggggg caggactggg ggccgggcga aatccaggca     60
ctgctgggct gcctgctcaa ggtgctgctc tgggtggcct ctgcttgctg tactttggaa    120
kcgaacaggc cgcccgcctt ctgggcagcc cctgcttacg gcgcctctac catgcctggc    180
tggcagcagt ggtcatcttt gggccgcttc tgcagttcca tgtcaaccct cggactatct    240
tcgccagcca cggcaacttc ttcaacataa aatttgtgaa ttcagcctgg ggctggacat    300
gcactttctt agggggcttt gtgttgctgg tggtgttcct ggctacacgg cgcgtggcag    360
taactgccag acacctgarc cgactggtag taggggcanc cgtgtggcgg ggarccggcc    420
gggccttcct gctcatcgag gacctgactg gctcctgctt cgagccactg ccccagggtc    480
tgctgctcca cgagctgcct gaccgccgca gctgcctggc agccggccac cagtggcgag    540
gctacaccgt ctcctcccac accttcctgc tcaccttttg ctgcctgctc atggcagagg    600
aagcagctgt gttcgccaag tacctgcgcc catgggcttc ctgccggcgc cccactgcgc    660
cttgtcttcc tgctgaacgt gctgctgctg ggcctctgga acttcttgct gctctgtacc    720
gtcatctatt tccaccagta cactcacaag gtggtgggcg ccgcagtggg cacctttgcc    780
tggtacctca cctatggcag ctggtatcat cagccctggt ctccagggag cccaggccat    840
gggctcttcc cccgtcccca ctccagccgc aagcataact gaaagaaata aaaaccatcg    900
ggcctgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                          940

<210> 648
<211> 2105
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (11)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<400> 648
caggctngta nantaacaat grratttggg tagggggaga aagatacctt ctaaaatgga     60
tcaatagaac caaaataata cagcatgttc tataaccaca aggaaatcaa atgatcctgt    120
catgattcca gttagtcata actatgttag cagtgctaaa tgcattttag aaatggtgac    180
ttctgtggtt ttcytagcat ttgtctctaa caaatggtga aataattact catggccctc    240
tctgccattg tctttcattt tttcacagtg aaattagacc cctttacttc accattctgc    300
cactgcaaat taagtataaa gaaaatagca agagtgtcca caccagtaga cagtaagctt    360
ctctacctgt aagtgatgaa atcatagcta atgcacttgc catggagttt tcaagatgat    420
tggtgtcaga cagttttcac tttgtttaaa aagtgttggt ggccttttgt ggtggtgtta    480
caatcctctg ggggcttagg aggatgttga tgcaactttt agaagctttt aatttcaaaa    540
acaactcaaa aatctgaagg acagtcatag ctgccactca gccccagtta gtcaaacccc    600
agtgaccttt gcccctggtt gccaagggct ttgcaacatc aagcagggaa ataaggatct    660
gtctgtttag tggataccgt gtatccttta atagaccagg taacagttcg tgttagttta    720
gactattgtt ttgtactgta ctttcttggg tggcagagga aagaaaagta aaacattaaa    780
aaaaaaaaaa aaaactgcgt tctttaaatt ctgtattatt agcaacctct gttgtacata    840
gtgtttgata ataaagtatt aatttgattc ttatgtcttt tgtaagtgag aacaatagac    900
tttmaggata caaaacatgc attgaggctt tgaaacatcc aatgtgtacc atggctgaaa    960
aaaagagtca caagtggctg agacactgct ccatacagga ctcatgtgtg gtcattgccc   1020
acccaatctt atgactccat catcttggga cctggaacaa catgactttt ttgatcgata   1080
ttttgtcctc ggtgttttca aggtctgatg ttggagccct gtggcccacc ctcccttctc   1140
caccagcatg ttggtttgaa aaggataggg ratttagaaa cagttctgta ctttggtttg   1200
gtttggtttt ctgtttgtga ttgttttcat ggactgtttt attttttccc aggaagagtc   1260
tttatcaata tcatgtgcag ctcactcatg gaaatggttg caaaccaatc agtgtaggaa   1320
gcttaaatgg ggctgtttcc ctctctgtgt cgttgtgaaa ggaagagtca cacagtacct   1380
gtggattttc agggactctg tttttctccg gtgccttagc aacggcagca gccatttgta   1440
ttattttcaa ataattagaa aaacagtttt caactcctcc tttccattca ttgctctcag   1500
agttgtggtc actgactttt cttttgaaaa ccgcctccac caacaccccc gtttgcctac   1560
accacccccc ttttacttag tatgtttatt ttttgtgtgt ctcttgcctt cctcccacgt   1620
tttatttccc ctcagagctg tgaatgggca ggtctgtctc tggtttggca tcactgagtt   1680
tttcccatgc attggcccca gggctgctag gatgtgagac aaatctccct acaatgggct   1740
tgctcccatt gtctgtacag tttaatagat gctggcatgt cggaggttac ccatgagtca   1800
aaatccgctc tccatgctta ctcttgacac cccattgaag ccactcattg tgtgtgcgtc   1860
tgggtgtgaa gtccagctcc gtgtggtcct gtgcttgtac tgccctgctt tgcagttcct   1920
ttgcacttac tcatcgagtg ctgttttgaa atgctgacat tatataaacg taaaagaaaa   1980
tgtaamaaaa aaaaacccac acacaaacaa acccatacga tctgtatttg tatatacacg   2040
tgtccgtaca agtataacta aataaaaatt aaagattttc atcattttaa aaaaaaaaaa   2100
aaaaa                                                               2105

<210> 649
<211> 912
<212> DNA
<213> Homo sapiens

<400> 649
cagcattcca ctggtcaggg aagactccat agagtaggca acatttgggc agtgttttga     60
agaatgacaa gggcctgcca gacagtacat gggggagaag gactttcagg ggagaggaac    120
agcatgggca aagttatgga ggcatgcaaa catctccctc ttctctccct tactttccaa    180
gcaagttagg tacgctttcc atggggattc tggcctgtgt ggtaggaagg gatctccctt    240
gctcccatgt tgctggctgt ccgtacatca ccctgtcccc tgcaggaggg ggctacaggc    300
catctccctc ctgtaggcct ctgactcccc tccacttttg ggccctcagc ttatctcggg    360
caggggacca ttgcagcatc ctcccctcct cggactcaag gtgctgaggt ataagccctg    420
ggccccagat ccctggtgac accttcctgg agaagactct caaaagtgac tgtatatttg    480
agttcaccag caataactcc ccacactcga agcaggtcca aacccaggat cycagggtcc    540
ttgggctctg tggcactgtc ttcccaagat ccttcctgtt gcacaatggg aaacctaaga    600
ggaaaaagac aggggcctgc ttgcccagcc atgcgaggga ttccatgccc acctgccctc    660
tgtctgcctc gctggaatgt gggcccctgc tccccgtcag gttgtgctgt ctctgaccta    720
tgtttacatc cccgaggggt ttctgcctcc tccccaccca ggtcagggtg tggtccagca    780
gcttgctgtg gggtgctgac atgtgtcacc actgcccccc ttgcccccgg gggggtcatg    840
gtctcctcct ggatgctgct ccttgaatct tttttcttga taaacctttt acaattaaga    900
taaaaaaaaa aa                                                        912

<210> 650
<211> 978
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (977)
<223> n equals a,t,g, or c

<400> 650
acagagtctc gctctgttgt ccagcctggg caacagagaa aacaaaaagg aaaacaaatg     60
atgaaggtct gcagaaactg aaacccagac atgtgtctgc cccctctatg tgggcatggt    120
tttgccrgtg cttctaagtg caggagaaca tgtcacctga ggctagtttt gcattcaggt    180
ccctggcttc gtttcttgtt ggtatgcctc cccagatcgt ccttcctgta tccatgtgac    240
cagactgtat ttgttgggac tgtcgcagat cttggcttct tacagttctt cctgtccaaa    300
ctccatcctg tccctcagga acggggggaa aattctccga atgtttttgg ttttttggct    360
gcttggaatt tacttctgcc acctgctggt catcactgtc ctcactaagt ggattctggc    420
tcccccgtac ctcatggctc aaactaccac tcctcagtcg ctatattaaa gcttatattt    480
tgctggatta ctgctaaata caaaagaaag ttcaatatgt tttcatttct gtagggaaaa    540
tgggattgct gctttaaatt tctgagctag ggattttttg gcagctgcag tgttggcgac    600
tattgtaaaa ttctctttgt ttctctctgt aaatagcacc tgctaacatt acaatttgta    660
tttatgttta aagaaggcat catttggtga acagaactag gaaatgaatt tttagctctt    720
aaaagcattt gctttgagac cgcacaggag tgtctttcct tgtaaaacag tgatgataat    780
ttctgccttg gccctacctt gaagcaatgt tgtgtgaagg gatgaagaat ctaaaagtct    840
tcataagtcc ttgggagagg tgctagraaa atataaggca ctatcataat tacagtgatg    900
tccttgctgt tactactcaa atcacccaca aatttcccca aagactgcgc tagctgtcaa    960
ataaaagaca gtgaaana                                                  978

<210> 651
<211> 739
<212> DNA
<213> Homo sapiens

<400> 651
gccgcgccct gcagattgtc tcttgttgcg taagtttttt tgaccgtcac tcgtgtcagc     60
ttcaaagtca gatagatttt tctcccagca tgttctactt ccgaggctgt ggccgttggg    120
tcgcggtttc cttcaccaag cagcaatttc cgttggcacg gttgagcagt gacagcgcgg    180
cgccccggac tccgcacttc gacgtgatag tcattggtgg aggacatgcc gggactgagg    240
cagccaccgc cgccgctcgg tgcggctctc ggactctgct cctcactcac cgcgtggaca    300
cgatcggtca gatgtcatgt aatccttcct ttggtggcat cggaaaggga catttaatga    360
gggaagtaga tgccttggat ggcctgtgtt ctcgcatctg tgaccagtct ggtgtacatt    420
ataaagtatt aaaccggcgt aagggaccag ctgtgtgggg tctgaragct cagattgata    480
ggaaactcta taaacagaac atgcagaaag aaatcttgaa tacaccactg sttactgttc    540
argarggarc tgtagaagat cttattctta cagaaccaga gcctgaacac actgggaaaw    600
gccgtgtcag tggggttgtt ttggtggatg gaagcacagt atatgcagag agtgtgattc    660
tgactactgg gacatttctg agaggcatga ttgtaattgg attggagacg catccagcag    720
gacgtttagg ggatcagcc                                                 739

<210> 652
<211> 2039
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2034)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2038)
<223> n equals a,t,g, or c

<400> 652
ggcacaggtt gctagaggct tcagaactcc agcctaatgg atcccaaact cgggagaatg     60
gctgcgtccc tgctggctgt gctgctgctg ctgctgctgc ggagcgcggc atgttctcct    120
caccctcccc gcccccggcg ctgttagaga aagtcttcca gtacattgac ctccatcagg    180
atgaatttgt gcagacgctg aaggagtggg tggccatcga gagcgactct gtccagcctg    240
tgcctcgctt cagacaagag ctcttcagaa tgatggccgt ggctgcggac acgctgcagc    300
gcctgggggc ccgtgtggcc tcggtggaca tgggtcctca gcaggtgctc gatggtcaga    360
gtcttccaat acctcccgtc atcctggccg aactggggag cgatcccacg aaaggcaccg    420
tgtgcttcta cggccacttg gacgtgcagc ctgctgaccg gggcgatggg tggctcacgg    480
acccctatgt gctgacggag gtagacggga aactttatgg acgaggagcg accgacaaca    540
aaggccctgt cttggcttgg atcaatgctg tgagcgcctt cagagccctg gagcaagatc    600
ttcctgtgaa tatcaaattc atcattgagg ggatggaaag aggctggctc tgtttgccct    660
ggaggaactt gtgggaaaaa gaaaaggacc gattcttctc tggtgtggac tacattgtaa    720
tttcagataa cctgtggatc agccaaagga agccagcaat cacttatgga acccggggga    780
acagctactt catggtggag gtgaaatgca gagaccagga ttttcactca ggaacctttg    840
gtggcatcct tcatgaacca atggctgatc tggttgctct tctcggtagc ctggtagact    900
cgtctggtca tatcctggtc cctggaatct atgatgaagt ggttcctctt acagaagagg    960
aaataaatac ataccaaagc catccatcta gacctaagaa gaataccgga atagcagccg   1020
ggttgagaaa tttctgttcg atactaagga ggagattcta atgcacctct ggaggtaccc   1080
atctctttct attcatggga tcgagggcgc gtttgaatga gcctggaact aaaacagtca   1140
tacctggccg agttatagga aaattttcaa tccgtctagt ccctcacatg aatgtgtctg   1200
cggtggaaaa acaggtgaca cgacatcttg aagatgtgtt ctccaaaaga aatagttcca   1260
acaagatggt tgtttccatg actctaggac tacacccgtg gattgcaaat attgatgaca   1320
cccagtatct cgcagcaaaa agagcgatca gaacagtgtt tggaacagaa ccagatatga   1380
tccgggatgg atccaccatt ccaattgcca aaatgttcca ggagatcgtc cacaagagcg   1440
tggtgctaat tccgctggga gctgttgatg atggagaaca ttcgcagaat gagaaaatca   1500
acaggtggaa ctacatagag ggaaccaaat tatttgctgc ctttttctta gagatggccc   1560
agctccatta atcacaagaa ccttctagtc tgatctgatc cactgacaga ttcacctccc   1620
ccacatcccc tagacaggga tggaatgtaa atatccagag aatttgggtc tagtatagta   1680
cattttccct tccatttaaa atgtcttggg atatctggat cagtaataaa atatttcaaa   1740
ggcacagatg ttggaaatgg tttaaggtcc cccactgcac accttcctca agtcatagct   1800
gcttgcagca acttgatttc cccaagtcct gtgcaatagc cccaggattg gattccttcc   1860
aaccttttag catatctcca accttgcaat ttgattggca taatcactcc ggtttgcttt   1920
ctaggtcctc aagtgctcgt gacacataat cattccatcc aatgatcgcc tttgctttac   1980
cactctttcc tttttcttat taataaaaat gttggtctcc aaaaaaaaaa aaanaaana    2039

<210> 653
<211> 1434
<212> DNA
<213> Homo sapiens

<400> 653
agaaacccat gataccctac tgaacaccga atcccctgga agcccacaga gacagagaca     60
gcaagagaag cagagataaa tacactcacg ccaggagctc gctcgctctc tctctctctc    120
tctcactcct ccctccctct ctctctgcct gtcctagtcc tctagtcctc aaattcccag    180
tcccctgcac cccttcctgg gacactatgt tgttctccgc cctcctgctg gaggtgattt    240
ggatcctggc tgcagatggg ggtcaacact ggacgtatga gggcccacat ggtcaggacc    300
attggccagc ctcttaccct gagtgtggaa acaatgccca gtcgcccatc gatattcaga    360
cagacagtgt gacatttgac cctgatttgc ctgctctgca gccccacgga tatgaccagc    420
ctggcaccga gcctttggac ctgcacaaca atggccacac agtgcaactc tctctgccct    480
ctaccctgta tctgggtgga cttccccgaa aatatgtagc tgcccagctc cacctgcact    540
ggggtcagaa aggatcccca ggggggtcag aacaccagat caacagtgaa gccacatttg    600
cagagctcca cattgtacat tatgactctg attcctatga cagcttgagt gaggctgctg    660
agaggcctca gggcctggct gtcctgggca tcctaattga gctggaaaag cttcagggga    720
cattgttctc cacagaagag gagccctcta agcttctggt acagaactac cgagcccttc    780
agcctctcaa tcagcgcatg gtctttgctt ctttcatcca agcaggatcc tcgtatacca    840
caggtgaaat gctgagtcta ggtgtaggaa tcttggttgg ctgtctctgc cttctcctgg    900
ctgtttattt cattgctaga aagattcgga agaagaggct ggaaaaccga aagagtgtgg    960
tcttcacctc agcacaagcc acgactgagg cataaattcc ttctcagata ccatggatgt   1020
ggatgacttc ccttcatgcc tatcaggaag cctctaaaat ggggtgtagg atctggccag   1080
aaacactgta ggagtagtaa gcagatgtcc tccttcccct ggacatctcc tagagaggaa   1140
tggacccagg ctgtcattcc aggaagaact gcagagcctt cagcctctcc aaacatgtag   1200
gaggaaatga ggaaatcgct gtgttgttaa tgcagagaac aaactctgtt tagttgcagg   1260
ggaagtttgg gatatacccc aaagtcctct accccctcac ttttatggcc ttttccctag   1320
atatactgcg ggatctctcc ttaggataaa gagttgctgt tgaagttgta tatttttgat   1380
caatatattt ggaaattaaa gtttctgact ttaaaaaaaa aaaaaaaaaa aaaa         1434

<210> 654
<211> 3296
<212> DNA
<213> Homo sapiens

<400> 654
gggcatgcct gaaggagggg gcgctctcgc agaaggcttt caagtgagga tgtttgagtt     60
tcagaatttt gagaggagat ttgaggagtg catctcccag tctgcagtga agaccaagtt    120
tgagcagcac acggtccggg ccaagcagat tgcagaggcg gttcgactca tcatggactc    180
cctgcacatg gcggctcggg agcagcaggt ttactgcrag gaaatgcgtg aagagcggca    240
agaccgactg aaatttattg acaaacagct ggagctcttg gctcaagact ataagctgcg    300
aattaagcag attacggagg aagtggagag gcaggtgtcg actgcaatgg ccgaggagat    360
caggcgcctc tctgtactgg tggacgatta ccagatggac ttccaccctt ctccagtagt    420
cctcaaggtt tataagaatg agctgcaccg ccacatagag gaaggactgg gtcgaaacat    480
gtctgaccgc tgctccacgg ccatcaccaa ctccctgcag accatgcagc aggacatgat    540
agatggcttg aaacccctcc ttcctgtgtc tgtgcggagt cagatagaca tgctggtccc    600
acgccagtgc ttctccctca actatgacct aaactgtgac aagctgtgtg ctgacttcca    660
ggaagacatt gagttccatt tctctctcgg atggaccatg ctggtgaata ggttcctggg    720
ccccaagaac agccgtcggg ccttgatggg ctacaatgac caggtccagc gtcccatccc    780
tctgacgcca gccaacccca gcatgccccc actgccacag ggctcgctca cccaggagga    840
gttcatggtt tccatggtta ccggcctggc ctccttgaca tccaggacct ccatgggcat    900
tcttgttgtt ggaggagtgg tgtggaaggc agtgggctgg cggctcattg ccctctcctt    960
tgggctctat ggcctcctct acgtctatga gcgtctgacc tggaccacca aggccaagga   1020
gagggccttc aagcgccagt ttgtggagca tgccagcgag aagctgcagc ttgtcatcag   1080
ctacactggc tccaactgca gccaccaagt ccagcaggaa ctgtctggga cctttgctca   1140
tctgtgtcag caagttgacg tcacccggga gaacctggag caggaaattg ccgccatgaa   1200
caagaaaatt gaggttcttg actcacttca gagcaaagca aagctgctca ggaataaagc   1260
cggttggttg gacagtgagc tcaacatgtt cacacaccag tacctgcagc ccagcagata   1320
gtgggcacct gaggcggagt ctgcgtggag aggggcggtg ctgccagccc taagtgccrt   1380
gtgggctccc ccaggggcac gtgtggctcc tgccccctgg ccactgccaa gagaatgaag   1440
cacccagtct cgtaccattt tgagccctcc agcactactt attttccccc acctttgcct   1500
gctgttgctg gaagagctgg ctcatacccc caaaggacac tttcagcgac agctatggac   1560
agcatggtac caaggagtta agttgaggct ttttccagct ttctctggtt catttgattg   1620
cttgataagg cctcaggatc tcagcattgc acaatgcctc atggaagcct ttgagggtat   1680
cacacagaca cccccacctt cctccagcct gtgcgcacct gccctccttg cagcccagca   1740
cacctgcagg tgtaagggac gattggagtt tcttcccaga gagtctgtcc cagaaggact   1800
gtggcttgtg tgtgtccatc tcgcctgttg gctcagtgct tcatcccatt tgcagagcct   1860
cagacacgtc ttggtggtga ggctcagtta cccctgggct taggctgagg cgggccctgt   1920
gctgggggtg gtagaaagga tgctgctgag gcagctggag gagtgggagt agctcagagg   1980
ggagggctgt tggatgtatg gggagctggc agagcaggtg gcagtcactg ggacaaggag   2040
ggacttgcct ctcttctcat tattgtgtcc tttgctttag tgtcagtcct ggacttgtgc   2100
aggcctgttt tgtgtagatc tgttttggaa gatggcatgg tctaggtggt tgaaggatgt   2160
agtagaagga tggatggtgg aaggtgggga cgttggtggc tggctgaggt gcatggsccc   2220
cacacaggac agctggagaa tgggccgtcc acttggcctc gttctgcgag gggctcatgg   2280
gtctgagagc ccccacccac taggcttgat tgcatccctg ttgtgccctt taagagacat   2340
gtttccaccc cacccccaac cttgtcccaa gtgccctgga ctaaatttcc tgtgccagtg   2400
actgcagttg gccaagggac aatgtggaaa acccagtgtc catctttcca ccctccctga   2460
tctccagaac cttcgactga cccccttgtc tttatgctga tgttgagttt tgggattgtt   2520
actggttgaa gtgggggcag atgcctgtca ccaaggtgtt gactgtgtga gaaaagcagt   2580
ttgggtgaca aatcctgtgt ggcacaagtt ggatcgcttc ctagaaataa gcaacacctc   2640
tcccaaaaag cagcccacaa ggcaggggcc cagcagccca gccatcactc atctttgagg   2700
aaatgagttg gtagcctctg tgcactgttt ggtggccaca tcacaggtga tgtcctgttc   2760
acatacctgc ttgtatttaa agccctcagt ctgtcctgtt gtgtggggcg aagtgatgga   2820
ctctgccagg tggacatgct gtgggtggat gttcccggcg tgtgccgggc ctgaatggac   2880
aggggccact tcacagcatg tcagggaaaa tcactgtcac acaattccaa tggattttgt   2940
gctctttttg aaaaaaaaaa attctttagc gtaaacatga attttttttc aatgtagccc   3000
ctggggaatg aatgaaattt tgagcttctt caatacgtaa aattaaattt ataccactga   3060
gggagagacc ctttctgaaa gaagtatggc caaaagcact ttaatgctgc tgacattgtt   3120
gtttttatgt tcatttgctg gagcgcaaga cgtgctgaca cagtgagttt tctctgatgt   3180
atttaaggtg atgtatttgc ttgagttact cctgtatcat tgctcataat attggaaact   3240
aaaataaaac ctagttggaa atccaaaaaa aaaaaaaaaa aaaacycgag gggggg       3296

<210> 655
<211> 663
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (656)
<223> n equals a,t,g, or c

<400> 655
gaattcggca cgagggcaga ggttgggaag atggcgtggc gaggctgggc gcagagaggc     60
tggggctgcg gccaggcgtg gggtgcgtcg gtgggcggcc gcagctgcga ggagctcact    120
gcggtcctaa ccccgccgca gctcctcgga cgcaggttta acttctttat tcaacaaaaa    180
tgcggattca gaaaagcacc caggaaggtt gaacctcgaa gatcagaccc agggacaagt    240
ggtgaagcat acaagagaag tgctttgatt cctcctgtgg aagaaacagt cttttatcct    300
tctccctatc ctataaggag tctcataaaa cctttatttt ttactgttgg gtttacaggc    360
tgtgcatttg gatcagctgc tatttggcaa tatgaatcac tgaaatccag ggtccagagt    420
tattttgatg gtataaaagc tgattggttg gatagcataa gaccacaawa agaaggrgac    480
ttcagaaagg agattaacaa gtggtgggaw taacctaagt gatggccagc ggactgtgra    540
cagtttgtkt tagcttacac gttttaaacc attcaaggaa gagaaatcaa accaaaaggt    600
attatagctg caaatgtccc ttgtantctg gtttatggga gagtaccttc ttctgncagc    660
ggg                                                                  663

<210> 656
<211> 2583
<212> DNA
<213> Homo sapiens

<400> 656
ggcacgagct gaactcccaa agggagtgtg tgtatttcct cccgttcttt atcagagccc     60
ccaaaataag taggaatggg cagtggstat tcacattcac tacacctttt ccatttgcta    120
ataaggccct gccaggctgg gagggaattg tccctgcctg cttctggaga aagaagatat    180
tgacaccatc tacgggcacc atggaactgc ttcaagtgac cattcttttt cttctgccca    240
gtatttgcag cagtaacagc acaggtgttt tagaggcagc taataattca cttgttgtta    300
ctacaacaaa accatctata acaacaccaa acacagaatc attacagaaa aatgttgtca    360
caccaacaac tggaacaact cctaaaggaa caatcaccaa tgaattactt aaaatgtctc    420
tgatgtcaac agctactttt ttaacaagta aagatgaagg attgaaagcc acaaccactg    480
atgtcaggaa gaatgactcc atcatttcaa acgtaacagt aacaagtgtt acacttccaa    540
atgctgtttc aacattacaa agttccaaac ccaagactga aactcagagt tcaattaaaa    600
caacagaaat accaggtagt gttctacaac cagatgcatc accttctaaa actggtacat    660
taacctcaat accagttaca attccagaaa acacctcaca gtctcaagta ataggcactg    720
agggtggaaa aaatgcaagc acttcagcaa ccagccggtc ttattccagt attattttgc    780
cggtggttat tgctttgatt gtaataacac tttcagtatt tgttctggtg ggtttgtacc    840
gaatgtgctg gaaggcagat ccgggcacac cagaaaatgg aaatgatcaa cctcagtctg    900
ataaagagag cgtgaagctt cttaccgtta agacaatttc tcatgagtct ggtgagcact    960
ctgcacaagg aaaaaccaag aactgacagc ttgaggaatt ctctccacac ctaggcaata   1020
attacgctta atcttcagct tctatgcacc aagcgtggaa aaggagaaag tcctgcagaa   1080
tcaatcccga cttccatacc tgctgctgga ctgtaccaga cgtctgtccc agtaaagtga   1140
tgtccagctg acatgcaata atttgatgga atcaaaaaga accccggggc tctcctgttc   1200
tctcacattt aaaaattcca ttactccatt tacaggagcg ttcctaggaa aaggaatttt   1260
aggaggagaa tttgtgagca gtgaatctga cagcccagga ggtgggctcg ctgataggca   1320
tgactttcct taatgtttaa agttttccgg gccaagaatt tttatccatg aagactttcc   1380
tacttttctc ggtgttctta tattacctac tgttagtatt tattgtttac cactatgtta   1440
atgcagggaa aagttgcacg tgtattatta aatattaggt agaaatcata ccatgctact   1500
ttgtacatat aagtatttta ttcctgcttt cgtgttactt ttaataaata actactgtac   1560
tcaatactct aaaaatacta taacatgact gtgaaaatgg caatgttatt gtcttcctat   1620
aattatgaat atttttggat ggattattag aatacatgaa ctcactaatg aaaggcattt   1680
gtaataagtc agaaagggac ataggattca catatcagac tgttaggggg agagtaattt   1740
atcagttctt tggtctttct atttgtcatt catactatgt gatgaagatg taagtgcaag   1800
ggcatttata acactatact gcattcatta agataatagg atcatgattt ttcattaact   1860
catttgattg atattatctc catgcatttt ttatttcttt tagaaatgta attatttgtt   1920
ctagcaatca tgctaacctc tagtttgtag aaaatcaaca ctttataaat acataattat   1980
gatattattt ttcattgtat cactgttcta aaaataccat atgattatag ctgccactcc   2040
atcaggagca aattcttctg ttaaaagcta actgatcaac cttgaccact tttttgacat   2100
gtgagatcaa agtgtcaagt tggctgaggt tttttggaaa gctttagaac taataarctg   2160
ctggtggcac tttgtaacgt atgattatct aagctgattt tgatgctaaa ttatcttagt   2220
gatctaaggg gcagtttagt gaagatggaa tcttgtattt aaaatagcct tttaaaattt   2280
gttttgtgat gatgtatttt gacaacttcc atctttagga gttatataat caccttgatt   2340
ttagtttcct gatgtttgga ctatttataa tcaaggacac caagcaagca taagcatatc   2400
tatatttctg actggtgtct ctttgagaag gatgggaagt agaaaaaaaa aaaagaaaga   2460
aaggaaagga agagaggaga gaagaaggca gggatctcca ctatgtatgt tttcacttta   2520
gaactgttga gcccatgctt aattttaatc tagaagtctt taaatggtga gacagtgact   2580
gga                                                                 2583

<210> 657
<211> 1867
<212> DNA
<213> Homo sapiens

<400> 657
cggctctgct ccactctgct cagctccgct ccaggaaggc cacctcctcc tccccctcct     60
cctcccgctg tcaccactca ccgctcataa cctcaagggg gtggggaccc cagggctgga    120
cacaccccac cgtggcccca gagctcagcc ggtcgcacgg acggacagtt ggaagccgga    180
ccccagagcc tgaggtgggc agtgtgccag ggtcccttgc ggcctcctca agccctgtcc    240
aggctatggg catcaagaca gcattgccgg cggctgagct gggcctctac tctctggtgc    300
tgagtggggc cctggcctat gctggccggg gcctccttga ggcttcacaa gatggggccc    360
acaggaaggc cttccgggag tctgtgcgac ctggctggga gtacattggc cggaagatgg    420
atgtggctga cttcgagtgg gtgatgtggt tcacctcctt tcgcaacgtc atcatctttg    480
ccctctccgg acatgtgctg tttgctaaac tctgcacgat ggttgcccca aagctccgcw    540
cctggatgta tgctgtgtac ggggccttgg ctgtgatggg cacaatgggc ccttggtacc    600
tgctgctgct gcttggtcac tgtgtgggcc tctatgtggc ctcgcttttg ggccagccct    660
ggctctgtct tggccttggc ttggccagcc tggcctcctt caagatggac cccctaatct    720
cttggcagag cgggtttgta acaggcactt ttgatcttca agaggtgctg tttcatgggg    780
gcagcagctt cacagtgctg cgttgcacca rctttgcact ggagarctgt gcccaccctg    840
accgccacta ctccttagct gacctgctca agtacaactt ctacctgccc ttcttcttct    900
tcgggcccat catgaccttt gatcgcttcc atgctcaggt gagccaggtg gagccagtga    960
gacgcgaggg tgagctgtgg cacatccgag cccaggcagg cctaagcgtg gtggccatca   1020
tggccgtcga catcttcttt cacttcttct acatcctcac tatccccagc gacctcaagt   1080
tcgccaaccg cctcccagac agtgccctcg ctggcctagc ctattcaaac ctggtgtatg   1140
actgggtgaa ggcggccgtc ctctttggtg ttgtcaacac tgtggcatgc ctcgaccacc   1200
tggacccacc ccagcctccc aagtgcatca ccgcactcta cgtctttgcg gaaacgcact   1260
ttgaccgtgg catcaacgac tggctttgca aatatgtgta taaccacatt ggtggggagc   1320
attccgctgt gatcccagag ctggcagcca cagtggccac atttgccatc accacactgt   1380
ggcttgggcc ttgtgacatt gtctacctgt ggtcattcct taactgcttt ggcctcaact   1440
ttgagctctg grtgcaaaaa ctggcagagt gggggcccct agcacgaatt gaggcctctc   1500
tgtcagtgca gatgtcccgt agggtccggg ccctgtttgg agccatgaac ttctgggcca   1560
tcatcatgta caaccttgtg agcctgaaca gcctcaaatt cacagagctg gttgcccggc   1620
gcctgctact cacagggttc ccccagacca cgctgtccat cctgtttgtc acctactgtg   1680
gcgtccagct ggtaaaggag cgtgagcgaa ccttggcact ggaggaggag cagaagcagg   1740
acaaagagaa gccggagtag gagggagcgg gtagagggat gggctctgct cagctattct   1800
tgggccagat ggggcctgac cgatagaata aaagactttt ctacaacaaa aaaaaaaaaa   1860
aaaaaaa                                                             1867

<210> 658
<211> 1824
<212> DNA
<213> Homo sapiens

<400> 658
gcccacgcgt ccgaacgggg tctatggttt ttctcatcaa gaggtcatga cgccagtcag     60
atcacactag ccttgggcac agctgcctcc taccccaggg cctgccaggc tctcggggcc    120
atgctgtcca aaggagccct gaaccctgct gacatcaccg tcctgttcaa gatgttcaca    180
agcatggacc ctcctccggt tgaacttatc cgcgttccag ccttcctgga cctgttcatg    240
cagtcactct ttaaaccagg ggctcggatc aaccaggacc acaagcacaa atacatccac    300
atcttggcgt acgcagcaag cgtggttgag acctggaaga agaacaagcg agtgagcatc    360
aataaagatg agctgaagtc aacgtcaaaa gctgtcgaaa ccgttcacaa tttgtgttgc    420
aacgagaaca aaggggcctc tgaactagtg gcagaattga gcacacttta tcagtgtatt    480
aggtttccag tggtagcaat gggtgtgctg aagtgggtgg attggactgt atcagaacca    540
aggtactttc agctgcagac tgaccatacc cctgtccacc tggcgttgct ggatgagatc    600
agcacctgcc accagctcct gcacccccag gtcctgcagc tgcttgttaa gctttttgag    660
actgagcact cccagctgga cgtgatggag cagcttgagt tgaagaagac actgctggac    720
aggatggttc acctgctgag tcgaggttat gtacttcctg ttgtcagtta catccgaaag    780
tgtctggaga agctggacac tgacatttca ctcattcgct attttgtcac tgaggtcagc    840
aatgsaccrt tggtttcatg tttcatactg tttacactag cactgccctt tttggcttaa    900
tttagttcat tttgtaccta actgagaact gtgctttctg atgtagtgat gacaatgaca    960
gatactcgtt taccaaaaag caccttctgc ctgcagcagc tgtatgacac actttacctc   1020
cattaccacc ctgggcatct gaatgttgga gatgggtggt gtcaccggcc ggtkggggtg   1080
gggagggatt ttttccaaac tgatggccat ttcacccgga tgtcggtgga tgccccgcac   1140
tagtgtgcga agaagtcacc ctgtgctccc ccacgcaggt gctggacgtc attgctcctc   1200
cttatacctc tgacttcgtg caacttttcc tccccatcct ggagaatgac agcatcgcag   1260
gtaccatcaa aacggaaggc gagcatgacc ctgtgacgga gtttatagct cactgcaaat   1320
ctaacttcat catggtgaac taatttagag catcctccag agctgaagca gaacattcca   1380
gaacccgttg tggaaaaacc ctttcaagaa gctgttttaa gaggctckgg cagcgtcttg   1440
aaaatgggca ccgctgggag gaggtggatg acttctttac aaaggaaaat ggtagcagct   1500
tcagtgagaa actgccctta caaacagtcc cttctctgct gtcaatccaa tactgctccc   1560
aaatcctgtt ttcagtgttc atttccctca aggcaggcgc tgggctccca cgacccctca   1620
ggacagatct ggccgtcagc cgcgggccgc tgggaactcc actcggggaa ctcctttcca   1680
agctgacctc agttttctca caagaaccca gttagctgat gttttattgt aattgtctta   1740
atttgctaag aacaagtaat aagtaaattt ttaaaaagcc tttctgctgg gttggattaa   1800
aaaaaaaaaa aaaaaaaaaa aaaa                                          1824

<210> 659
<211> 868
<212> DNA
<213> Homo sapiens

<400> 659
aaactatgtt aacggaactc ctgagaggtg gatcctttga gtttaaggac atgcgtgttc     60
cttcagcgct tgttacttta catatgctcc tgtgctctat ccccctctca ggwcgtttgg    120
atagtgatga acagaaaatt cagaatgata tcattgatat tttactgact tttacacaag    180
gagttaatga aaaactcaca atctcagaag agactctggc caataatact tggtctttaa    240
tgttaaaaga agttctttct tcaatcttga aggttcctga aggatttttt ttctgggact    300
catactcctt tcagagctgc tgcctcttcc attgcccatg caaacaactc aggttattga    360
gccacatgat atatcagtgg cactcaacac ccgaaaattg tggagcatgc accttcatgt    420
tcaagcaaag ttgctccaag aaatagttcg ctctttctct ggcacaacct gccagcccat    480
tcaacatatg ttacggcgta tttgtgttca attgtgtgac cttgcctcac caactgcact    540
tctgattatg agaactgtgt tggatttgat tgtagaagac ttgcaaagca cttcagaaga    600
taaagaaaaa cagtatacta gccaaaccac caggttgctt gctcttcttg atgctctggc    660
ttcacacaaa gcttgtaaat tagctatttt gcatctaatt aatggaacta ttaaaggtga    720
tgaaagatat gcagagatat tccaggatct tttagctttg gtgcggtctc ctggagacag    780
tgttattcgc caacagtgtg ttgaatatgt ccatccattt tgcagtctct ctgtactttc    840
agctccagaa tctcttcaga atctgttg                                       868

<210> 660
<211> 836
<212> DNA
<213> Homo sapiens

<400> 660
ccgtgtccat ctytttrata tcatcaccca gtaccgtgcc atcttctcar acgaggaccc     60
actgctgccc cctgccatgg gtgagcacac tgtgaatgag agtgccatct tccatggctg    120
ggtgctacag aaggtctcac aattcctgca ggtgctggag accgaccttt accggggcat    180
aggcggccac ctggactctc tgctgggcca gtgcatgtac tttgggctgt ccttcagccg    240
ggtgggagct gatttccggg gtcagttggc tcctgttttc cagcgggtgg ccatcagcac    300
tttccagaaa gcaattcagg aaacagtgga gaaattccag gaagaaatga actcctacat    360
gctcatctcg gctccagcca tcctgggcac cagtaacatg cctgctgctg tgccagccac    420
ccagccgggg acgctgcagc cacccatggt gctcctagat ttcccacccc tcgcctgctt    480
tctcaacaat attctggttg ccttcaatga tctgcgcctc tgctgccctg tggccctggc    540
gcaggatgtg actggggcct tggaagatgc ccttgccaag gtaactaaaa taatcctggc    600
cttccatcgc gctgaagagg ctgccttcag cagcggggag caagagctct ttgtccagtt    660
ctgcactgtc ttcctggaag accttgttcc gtatttaaat cgctgtctcc aagtcctttt    720
tccaccagct cagatagcac agactttagg taagagaatg aaaattctgt aaactgcctt    780
actgatgtgt aattcacata ctaaataatt catccatttg tgtaaaaaaa aaaaaa        836

<210> 661
<211> 735
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<400> 661
cgngatttan aantaggncg cccttttttt tttttttttt tttttttttt tttttttttt     60
tttttttttt tttttttttt tttttttttc agactttcag cccctttaat taggtgctct    120
gagaagaggt cagaatggca ggcagggggt ggggaaggcg gtgcttcttg agccccactt    180
agcaactggt cactcatcct ctggcagctg gatcttgctg gggtcgaagc agttggattc    240
catgatggga aggccattgg ctctcggtat ttcacaagcc tctcagcttc gcggcgggac    300
cactctttca tcccatccca cgctcttgga caccctgtgc acctgtagtc aggcagatag    360
gccacaaagg tgctgccaag gaccaggatg atggagacgc caaagaagaa gacaagtcgc    420
atgttccaga cgtccaaaac ggggtccttg tcataaccat gggagtctgg gttcttctca    480
tacaagtttt cgtcctcggg ttctgggtcc tcttgccacg gtgtggtcgg ttctgggggc    540
cgctttcccg ccacagcgga cggggcgacc acagtcctgg agaagctaga ttcccagcgg    600
acgcgggcgg ccgggagccc tcgcgtcgcc gctgccgcca aaagacggcg agcgctcaaa    660
ccaaacagcc cagccgccat gacagatggt gctgcagggt ctcccccttc tgtcgtcttc    720
tcggagccgt acaac                                                     735

<210> 662
<211> 692
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (32)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (651)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (684)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (692)
<223> n equals a,t,g, or c

<400> 662
aatttatacg actcactatg ggnaatttgc cntcgagcca aaattcggca cgagggctgt     60
ttggtttgag cgctcgccgt cttttggcgg cagcggcgac gcgagggctc ccggccgccc    120
gcgtccgctg ggaatctagc ttctccagga ctgtggtcgc cccgtccgct gtggcgggaa    180
agcggccccc agaaccgacc acaccgtggc aagaggaccc agaacccgag gacgaaaact    240
tgtatgagaa gaacccagac tcccatggtt atgacaagga ccccgttttg gacgtctgga    300
acatgcgact tgtcttcttc tttggcgtct ccatcatcct ggtccttggc agcacctttg    360
tggcctatct gcctgactac aggatgaaag agtggtcccg ccgcgaagct gagaggcttg    420
tgaaataccg agagccaatg gccttcccat catggaatcc aactgcttcg accccagcaa    480
gatccagctg ccagaggatg agtgaccagt tgctaagtgg ggctcaagaa gcaccgcctt    540
ccccaccccc tgcctgccat tctgacctct tctcagagca cctaattaaa ggggctgaaa    600
gtctgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa naaaaaaaaa    660
aaaaaaaaaa aaaaaaaaaa aaangggggg gn                                  692

<210> 663
<211> 1250
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1209)
<223> n equals a,t,g, or c

<400> 663
cgcgtccgcc cacgcgtccg cccacgcgtc cgcccacgcg tccgctcagg aggcgggagg     60
aggacccgga atgaagacga aggcgctcac cattaaatcg tacggctcgc actgccccct    120
gcccgcagtc cagcgtcttc aaccgtttct gcggcagctc tggaggccgc ggctttggct    180
cagggaaagc catgctccca ggactccttc cttgcagcct taaatcggtc tgtacggaaa    240
attccgcgcc ttagaaaccc acgcttgggt gtaaccttat tattgttctt cctgacctac    300
ttcctgttta tcacttccgg gttcatcatt ttggcatttc ggtgatcggg ttggaactat    360
tgaagcccgc tttcaggttc ttttccccat tttccctttg aaaggaagac ttctggcttc    420
tcctaaatct ccgttctctg ggtaagggga gtccaagcct ctgtcatgag gaacggaaat    480
gcgagggcct cgggtgttac tctaaaatcc gccctcagct tgcacgccgg aagctgcgat    540
tcctgcagcg gaagaggcgt gatctggcct tcgactcgct atgtccacta acaatatgtc    600
ggacccacgg aggccgaaca aagtgctgag gtacaagccc ccgccgagcg aatgtaaccc    660
ggccttggac gacccgacgc cggactacat gaacctgctg ggcatgatct tcagcatgtg    720
cggcctcatg cttaagctga agtggtgtgc ttgggtcgct gtctactgct ccttcatcag    780
ctttgccaac tctcggagct cggaggacac gaagcaaatg atgagtagct tcatgctgtc    840
catctctgcc gtggtgatgt cctatctgca gaatcctcag cccatgacgc ccccatggtg    900
ataccagcct agaagggtca cattttggac cctgtctatc cactaggcct gggctttggc    960
tgctaaacct gctgccttca gctgccatcc tggacttccc tgaatgaggc cgtctcggtg   1020
cccccagctg gatagaggga acctggccct ttcctaggga acaccctagg cttacccctc   1080
ctgcctccct tcccctgcct gctgctgggg gagatgctgt ccatgtttct aggggtattc   1140
atttgctttc tcgttgaaac ctgttgttaa taaagttttt cactctgaaa aaaaaaaaaa   1200
aaaaaaaanc tygrgggggg gcccggaacc caattcsccg gatagtgagt              1250

<210> 664
<211> 1606
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1310)
<223> n equals a,t,g, or c

<400> 664
aagcttggca cgaggctgga agaattcgcg gcctgggtct agttggcggc ggggtcgggt     60
ccgcgcgagc cgcgatggag ctgcacatcc tagaacaccg ggtgcgggtg ctgagcgtcg    120
cccgtcccgg tctctggctc tacacccacc cgctcatcaa gctgctcttc ctgccccgcc    180
gcagccggtg caagttcttc agcctgacgg agacccctga ggattacacg cttatggtgg    240
acgaggaggg ctttaaagag ctgcccccat ctgagttcct gcaagtagct gaggccacat    300
ggctggtgct gaacgtgtcg tctcacagcg gtgcggcagt gcaggctgct ggggtcacca    360
agatcgcccg ttcggtcatc gcgccactgg ccgagcacca cgtgtctgtg ctgatgctgt    420
ccacttacca gacggacttc atcctggtgc gggagcagga cctgtccgtg gtgatccaca    480
cgctggccca ggagttcgac atttaccgcg aggtgggcgg agagcctgtg cctgtgacga    540
gggatgattc cagcaatggc tttccccgca ctcagcatgg gcccagcccc acggtgcatc    600
ccatccagag cccacagaac cgcttctgtg tcctcacact ggaccctgag acgcttccag    660
ccatcgccac caccctcata gatgtcctct tctactcgca cagcaccccc aaggaggcag    720
cctctagcag tcctgaaccc agctccatca cgttctttgc cttctccctc atcgagggtt    780
atatctccat tgtcatggat gctgaaacac agaaaaagtt ccccagtgac ctcctgctga    840
ccagctcctc gggggagctg tggaggwtgg tgcgcatcgk tggacagccc ctgggctttg    900
atgaatgtgg catcgtggca cagattgcag gtcccctggc tgccgctgac atctctgcct    960
actacatcag caccttcaac ttcgaccacg ccctggtgcc cgaggacggt atcggcagcg   1020
tcatcgaggt cctccagcgg cggcaggaag gcctggcttc ctgaggccca tgggcaacag   1080
agcagcctcc ctgctctccc ctcgacccag gcttccaaag acttctctaa gctatttcct   1140
taagctctgg aacgagcccc ctgttctgct ggggaccctc gttccgctct ctgtatgtaa   1200
gctgcgtgca ggcaccggct tttacgcgga cacctgtgta cactcacagg tggagtgggc   1260
aggtgctagc ctgactgcgt gtctgcccat gcaggggaac acggtgctcn gggcttaagc   1320
ccccaaccca tcactccctg cgcagcctcg gcgtttgcac agtccctgcc tgaggcctga   1380
gccattcccc aaaggcttcc tgggccagct gccccsctga cctccgttct gcctctggtg   1440
gggttgcctt ccctggccag gtgagtcctg acagtgcctc tccctcctgg ggcctccaag   1500
gaaagtattt tgacatctct ctctcttctg tttttattga cttgttaata aaggactttg   1560
tagtgacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                  1606

<210> 665
<211> 2051
<212> DNA
<213> Homo sapiens

<400> 665
cgctcccggg gaggtgttgc agccatggct acggcagccg gcgcgaccta ctttcagcga     60
ggcagtctgt tctggttcac agtcatcacc ctcagctttg gctactacac atgggttgtc    120
ttctggcctc agagtatccc ttatcagaac cttgggcccc tgggcccctt cactcagtac    180
ttggtggacc accatcacac cctcctgtgc aatgggtatt ggcttgcctg gctgattcat    240
gtgggagagt ccttgtatgc catagtattg tgcaagcata aaggcatcac aagtggtcgg    300
gctcagctac tctggttcct acagactttc ttctttggga tagcgtctct caccatcttg    360
attgcttaca aacggaagcg ccaaaaacaa acttgaagtt gtctgaaagc ttgctctaca    420
cttttacatt catcctcacc cttttttttg tggggtagag gaggtgcagt aatttactca    480
gtgatctttc tactttctag aaactgtcct tcaaagctct ttaagacccc ctcgttagtc    540
agttttttct cttatatgct ctggttgagc ttgaatagac cagttgttac ttaagaaaga    600
aacagagaaa gattttagct tttcaatcct atttggcaga ggacttcagc taccttctta    660
cagtctttgg ctgtgttggt accctcgtgt gctctgagct aagccacata ctaaactgac    720
tttttggttt gtataccctt gctcccgcct tctgatgaaa acaccttacc ctcacaacca    780
ccatctttcc tctcctttcc aaagctcttt ccaccttgct gcactaagat aaagtgacac    840
ttycactata tgtcaattcc acacacattt attaggtacc tgtgaggtag gatcctatcc    900
tctcaaactt ccatttctca tgctacagag aaagataagg aagatgagca agtgcctgga    960
atggggcagg ctgagcagtc acacaggcat agaggcacgc tgagaacctg gaggggagac   1020
tgcagagtgc cttccctgat gctgcagccg gaagtgatcc ttccctccac ctggcccctg   1080
ggacactgtg ctctgcagtg tgcagggcct gatggcactg ctagattgct ccttcagctc   1140
agggccacag cttaaacagc tttacctttc ccctcagcac ctgtcccact atcttgcaca   1200
caggtgctct aaccatgttt attgaacaaa ggagggaaac tgatttcact ttcacttgtt   1260
cattatcatt ccaattttta tgtgaaaatg gcacaaccca tttggggtac cctcacccca   1320
aaataaaagc ccaagtctac ctttgactgg taccaccttt tttgtggttt cgttggtgag   1380
aaacctttat ctttttcata cctttctatt ctcaatcact tctccaaaag tgtgtctttc   1440
cagctctgat ttaytcaaaa cacaagcatt yctgtttaga gattctagcc catgggttat   1500
ctggctagtt attacctctc ctgttcactt agttatactt tattattgct cacaggctgg   1560
ggaggcagaa tgactctgtc accactagga gccattaggg cttcttccct ggaggactgc   1620
ctgcttgctt tctggggaca ctagccctca tttcccttct gtggtacagt ggggcaaatt   1680
atttgtatta agcaaacatt tatgggaaac aacccgctcc cgaaaacgga gcccccaagt   1740
aaagcacaac cctgaaagat tatgaactat gaattgtctc trgtagagat aaatttctgc   1800
aaacatatct cagtcttccc tctgtttctc tggtgattaa gaagttcctt tttggtaagg   1860
aaaaggattt ttaaccatag agttaggcat catggaaatt caaaccagat ttcttaatac   1920
ctggtcttcc tcaaagagaa ataataacag taatagtggt gctgggaaca atatggcaga   1980
ttattgaatg aaattgatta acttgaataa aatgctgtga attttctcta aaaaaaaaaa   2040
aaaaaaaaaa a                                                        2051

<210> 666
<211> 414
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (257)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (397)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (399)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (407)
<223> n equals a,t,g, or c

<400> 666
ggataattta tgaagaacag aaatttgttt cccacagttc tgaaggttgg gggaagtcca     60
aaatcaaggc tccagcagat acagtgtttg ataagttgcc ctctgctttc aagatggtcc    120
cttgtttctg tgtcctcact tggcagaagg aatgaacttg ctcccttgag tccttatata    180
aagtcattaa tcctatccat aagggtggag ctagtatggc ctaatcatct catgaaagcc    240
ccacctcttt atttttnatt tttggtagag atggggtctc actgtgttgc ccaggctggt    300
gtcgaattcc taggctcaat gatccttctg cttgggcctc ggaatgctgt ggttacaggt    360
gtgagccaca cctcttaaat cccgttggca tgggggntna agtttcnaaa agga          414

<210> 667
<211> 835
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (826)
<223> n equals a,t,g, or c

<400> 667
gcggcgggtg cgctccttcc acggcccgca caccacctgc ctgcatgcgg cctgcgggcc     60
cgtgcgcgcc tcccacctgg cccgcaccaa gtacaacaac ttcgacgtgt acatcaagac    120
gcgctggctg tacggcttca tccgcttcct actctacttt agctgcagcc tgttcactgc    180
ggcgctctgg ggtgcgctgg ccgccctctt ctgcctacag tacctgggcg ttcgcgtcct    240
gctgcgcttc cagcgcaagc tgtwcggtgc tgctgctgct gctgggccgc cggcgcgtgg    300
acttmcgcct ggtgaacgag ctgctcgtct atggcatcca cgtcaccatg ctgctggtcg    360
ggggctgggc tggtgcttca tggtcttcgt ggacatgtga gggccgtggg tgcgagcttg    420
atgtatcgtc ccggcctgtg gctgtgttct ctccatgggt ggggtcggcc agcgccttcc    480
cttcgcccat cccccaggca gtcgctgctg cccggcgccc acggagagaa aagaaagggc    540
tgagacttct gtgatggggg cgcggacacc acccctaggc tggcttcctg gacccaccct    600
ccccgtatgc actctcaggg gcagcgccca cctgccggtg gctcctgctc acatgtcttc    660
gggtcgtact gcggggtggg ccctccgttc cgcctctctg tgggcctctc tccaggacca    720
cagctgccag ggactttaga catcaccctg ggaggccctg gacacagagg gytgtktgcc    780
caggagcaat tccggagggg gcctcctggc tgcacagccc ttctgntgcc tggcc         835

<210> 668
<211> 593
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (574)
<223> n equals a,t,g, or c

<400> 668
acgcgtgggc ggggcggtac caagatggac tcctcgcggg cccggcagca gctccggcgg     60
cgattcctcc tcctgccgga cgccgaggcc cagctggacc gcgagggtga cgccgggccg    120
gaaacctcca cagctgttga gaaaaaggag aaacctcttc caagacttaa tatccattct    180
ggattctgga ttttggcatc cattgttgtg acctattatg ttgacttctt taaaaccctt    240
aaagaaaact tccacactag cagctggttt ctctgtggca gtgccttgtt gcttgtcagt    300
ttatcaattg cattttactg catagtctac ctggaatggt attgtggaat tggagaatat    360
gatgtcaagt atccagcctt gatacccatt accactgcct cctttattgc agcaggaatt    420
tgcttcaaca ttgctttatg gcatgtgtgg tcgtttttca ctccattgtt gttgtttacc    480
cagtttatgg gggttgtcat gtttatcaca mtccttggat gatttccgaa gagacagggt    540
cttctatgtt gcccaggctg tctttgaact cctnggatca agtgatcctc ctt           593

<210> 669
<211> 450
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (344)
<223> n equals a,t,g, or c

<400> 669
tcgcccacgc gtccggagtt tagcaacttt gcatgttatg accacatttc tctataggat     60
actgccacaa catgtcaact gtcctggagg aattaatgcc tggaatacta tcacctctta    120
tatagacaac caaatctgtc aagggcaaaa gaacctttgc aataacactg gggacccaga    180
aatgtgtcct gagaatggat cttgtgtacc tgatggtcca ggtcttttgc agtgtgtttg    240
tgctgatggt ttccatggat acaagtgtat gcgccagggc tcgttctcac tgcttatgtt    300
cttcgggatt ctgggagcca ccactctatc cgtctccatt ctgnctttgg gcgacccagc    360
gccggaaaag ccaagacttc atgaactaca taggtcttac cattgaccta agatcaatct    420
gaactawctt agcccagtca gggagcyctg                                     450

<210> 670
<211> 1575
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1482)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1521)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1524)
<223> n equals a,t,g, or c

<400> 670
gcattgcatg gttcactgtc ttttactttg gcaatggctg gattcctacc ctcatcacgg     60
cctttgtyct tgctacctct caggcccaag ctgkatggct gcaacatgat tatggccacc    120
tgtctgtcta cagaaaaccc aagtggaacc accttgtcca caaattcgtc attggccact    180
taaagggtgc ctctgccaac tggtggaatc atcgccactt ccagcaccac gccaagccta    240
acatcttcca caaggatccc gatgtgaaca tgctgcacgt gtttgttctg ggcgaatggc    300
agcccatcga gtacggcaag aagaagctga aatacctgcc ctacaatcac cagcacgaat    360
acttcttcct gattgggccg ccgctgctca tccccatgta tttccagtac cagatcatca    420
tgaccatgat cgtccataag aactgggtgg acctggcctg ggccgtcagc tactacatcc    480
ggttcttcat cacctacatc cctttctacg gcatcctggg agccctcctt ttcctcaact    540
tcatcaggtt cctggagagc cactggtttg tgtgggtcac acagatgaat cacatcgtca    600
tggagattga ccaggaggcc taccgtgact ggttcagtag ccagctgaca gccacctgca    660
acgtggagca gtccttcttc aacgactggt tcagtggaca ccttaacttc cagattgagc    720
accacctctt ccccaccatg ccccggcaca acttacacaa gatcgccccg ctggtgaagt    780
ctctatgtgc caagcatggc attgaatacc aggagaagcc gctactgagg gccctgctgg    840
acatcatcag gtccctgaag aagtctggga agctgtggct ggacgcctac cttcacaaat    900
gaagccacag cccccgggac acygtgggga aggggtgcag gtggggtgat ggccagagga    960
atgatgggct tttgttctga ggggtgtccg agaggctggt gtatgcactg ctcacggacc   1020
ccatgttgga tctttctccc tttctcctct cctttttctc ttcacatctc ccccatagca   1080
ccctgccctc atgggacctg ccctccctca gccgtcagcc atcagccatg gccctcccag   1140
tgcctcctag ccccttcttc caaggagcag agaggtggcc accgggggtg gctctgtcct   1200
acctccactc tctgccccta aagatgggag gagaccagcg gtccatgggt ctggcctgtg   1260
agtctcccct tgcagcctgg tcactaggca tcacccccgc tttggttctt cagatgctct   1320
tggggttcat aggggcaggt cctagtcggg cagggcccct gaccctcccg gcctggcttc   1380
actctccctg acggctgcca ttggtccacc cywtcataga gtgctctgac cctgggcttt   1440
cacgggcccc attccaccgc ctccccaact tgagcctgtg ancttgggac caaaggggga   1500
tcctcgtctc ttgtgactca ncanaagcag tggccacgtt caaggaaggg ccgctggcct   1560
tggaagctca accca                                                    1575

<210> 671
<211> 884
<212> DNA
<213> Homo sapiens

<400> 671
tttttcataa ccacctcaaa tgtgattcaa ataagtccta agttttaaat atatcaaaaa     60
ttaatgggaa actcttcgcg atttgtgatg tctaacgggc catttcatgt aacagaacgt    120
ttccatacac cgctatccat ctaaatttaa atcacttttt cagagaactg cgtaagtatt    180
acgcatgttt tccctgtcat tcatccagaa tctaatcacc agactaatga ttccatcaat    240
cctggcgcat tttagtcaaa acgggggaaa attttttcaa caaatgctca accagcattg    300
ggtatatcca gtacactcca cgctttactt aagtctagat atttgtggga gaaaggatgc    360
ctggttcatt acgtaaaatg ccggtctggt taccaatagt catattgctc gttgccatgg    420
cgtctattca gggtggagcc tcgttagcta agtcactttt tcctctggtg ggcgcaccgg    480
gtgtcactgc gctgcgtctg gcattaggaa cgctgatcct catcgcgttc tttaagccat    540
ggcgactgcg ctttgccaaa gagcaacggt taccgctgtt gttttacggc gtttcgctgg    600
gtgggatgaa ttatcttttt tatctttcta ttcagacagt accgctgggt attgcggtgg    660
cgctggagtt caccggacca ctggcggtgg cgctgttctc ttctcgtcgc ccggtagatt    720
tcgtctgggt tgtgctggcg gttcttggtc tgtggttcct gctaccgctg gggcaagacg    780
tttcccatgt cgatttaacc ggctgtgcgc tggcactggg ggccggggct tgttgggcta    840
tttacatttt aagtgggcaa cgcgcaggag cggaacatgg ccct                     884

<210> 672
<211> 576
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (545)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (550)
<223> n equals a,t,g, or c

<400> 672
ggaaggctga ggtgtgcgcc tttttttttt ttccttctta gtcgtgtgta catcattggg     60
aatggaggga aataaatgac tggatggtcg ctgcttttta agtttcaaat tgacattcca    120
gacaagcggt gcctgagccc gtgcctgtct tcagatcttc acagcacagt tcctgggaag    180
gtggagccac cagcctctcc ytgaataact gggagatgaa acaggaagct ctatgacaca    240
cttgatcgaa tatgacagac acygaaaatc acgactcakc cccctccagc acctctacct    300
gttgcccgcc gatcacagcc ggaatgcagc tgaaagattc cctggggcct ggttccaacy    360
gcccactgtg gactctgagg cctctgcatt tgcgggtggt ctgcctgtga tattttggtc    420
atgggctggt ctggtcggtt tcccatttgt ctggccagtc tctrtgtgtc ttaatccctt    480
gtccttcatt aaaagcaaaa ctaaagaaaa aaaaaaaaaa aaaaaaaaaa aatttggggg    540
ggggncccgn tacccaattg ggcctttagg gggggg                              576

<210> 673
<211> 1468
<212> DNA
<213> Homo sapiens

<400> 673
ggaattggtg tgacagtgcc atcgagtacc tgttggatca gactgatgtg ttggtggttg     60
gtgtcctggg cctccagggg acaggcaagt ccatggtcat gtcattgttg tcagccaaca    120
ctccagagga ggaccagagg acttatgttt tccgggccca gagcgctgaa atgaaggaac    180
gagggggcaa ccagaccagt ggcatcgact tctttattac ccaagaacgg attgttttcc    240
tggacacaca gcccatcctg agcccttcta tcctagacca tctcatcaat aatgaccgca    300
aactgcctcc agagtacaac cttccccaca cttacgttga aatgcagtca ctccagattg    360
ctgccttcct tttcacggtc tgccatgtgg tgattgttgt ccaggactgg ttcacagacc    420
tcagtctcta caggttcctg cagacagcag agatggtgaa gccctccacc ccatccccca    480
gccacgagtc cagcagctca tcgggctccg atgaaggcac cgagtactac ccccacctag    540
tcttcttgca gaacaaagct cgccgagagg acttctgtcc tcggaagctg cggcagatgc    600
acctgatgat tgaccagctc atggcccact cccacctgcg ttacaaggga actctgtcca    660
tgttacaatg caatgtcttc ccggggcttc cacctgactt cctggactct gaggtcaact    720
tattcctggt acccttcatg gacagtgaag cagagagtga aaacccacca agagcaggac    780
ctggttccag cccactcttc tccctgctgc ctgggtatcg tggccacccc agtttccagt    840
ccttggtgag caagctccgg agccaagtga tgtccatggc ccggccacag ctgtcacaca    900
cgatcctcac cgagaagaac tggttccact tacgctgccc ggatctggga tggggtgaga    960
aagtcctytg ctctggcaga gtacagccgc ctgctggcct gaggccaagg agaggaatgt   1020
catgcagggg acctcctggg tccgcagtgt actgcgaggg agcacagatg tccatccccc   1080
gctggggtgg agagcggcag caggcctgat ggatgaggga tcgtggcttc ccggcccaga   1140
gacatgaggt gtccagggcc aggcccccca ccctcagttg gggctgttcc gggggtgact   1200
gtgagcgatc ccaccccaaa cctgagatgg ggtagcccgt cctgtgtcct ccacagggac   1260
aagcagtggg aggagtctga atggtcacca ggaagcccgg gctccatctt gacctccttt   1320
ttcagggaca ggagcaacag gcccctcttc cctgactcta agcccttccc tgtaaggtga   1380
ggcagggtct ggagagctct ttattggaac agatctggtg gttcaaataa acacagtcat   1440
gcaaaaaaaa aaaaaaaaaa aaaaaaaa                                      1468

<210> 674
<211> 469
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (400)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (431)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (456)
<223> n equals a,t,g, or c

<400> 674
aacctaagca acncattatg ggcagtggga ttttgggact cgcctttgcc ctggaaacac     60
tggaatccta ctttttctgg tacttttgac ttcagtgaca ttgctgtcta tatattcaat    120
aaacctccta ttgatctgtt caaaagaaac aggctgcatg gtgtatgaaa agctggggga    180
acaagtcttt ggcaccacag ggaagttcgt aatctttgga gccacctctc tacagaacac    240
tggagcaatg ctgagctacc tcttcatcgt aaaaaatgaa ctaccctctg ccataaagtt    300
tctaatggga aaggaagaga cattttcagc ctggtacgtg gatggccgcg ttctggtggt    360
gatagttacc tttggcataa ttctccctct gtgtctcttn gaagaactta gggtatcttk    420
ggctataact nagtgggatt ttcccttgga gctgtnatgg gtttttttt                469

<210> 675
<211> 1120
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1108)
<223> n equals a,t,g, or c

<400> 675
ggggacccgg agmgggaaga tggcggcggc gcaggaggcg gacggggccc gcagcgccgt     60
ggtggcggcc gggggaggca gctccggtca ggtgaccagc aatggcagca tcgggaggga    120
cccgccagcg gagacccagc ctcagaaccc accggcccag ccggcaccca atgcctggca    180
ggtcatcaaa ggtgtgctgt ttaggatctt catcatctgg gccatcagca gttggttccg    240
ccgagggccg gcccctcagg accaggcggg ccccggagga gccccacgcg tcgccagccg    300
caacctgttc cccaaagaca ctttaatgaa cctgcatgtg tacatctcag agcacgagca    360
ctttacagac ttcaacgcca cgtcggcact cttctgggaa cagcacgatc ttgtgtatgg    420
cgactggact agcggcgaga actcagacgg ctgctacgag cactttgctg agctcgatat    480
cccacagagc gtccagcaga acggctccat ctacatccac gtttacttca ccaagagtgg    540
cttccaccca gacccccggc agaaggccct gtaccgccgg cttgccacag tccacatgtc    600
ccggatgatc aacaaataca agcgcagacg atttcagaaa accaagaacc tgctgacagg    660
agagacagaa gcggacccag aaatgatcaa gagggctgag gactatgggc ctgtggaggt    720
gatctcccat tggcacccca acatcaccat caacatcgtg gacgaccaca cgccgtgggt    780
gaagggcagt gtgccccctc ccctggatca atatgtgaag ttcgacgccg tgagcggtga    840
ctactatccc atcatctact tcaatgacta ctggaacctg cagaaggact actaccccat    900
caacgagagc ctggccagcc tgccgctccg gtctccttct gyccrctctc gctttggcgc    960
tggcagctct atgctsccca gagcaccaag tcgccctggg aacttcctgg gcgattgagt   1020
ttgtacggag cagtcaagat tgagggagca gggacttcgg ttgaaggtgg ccctgcttgg   1080
aggaccaacc cttacctgtt ggcgtttnac cattcatcgg                         1120

<210> 676
<211> 835
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (630)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (803)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (823)
<223> n equals a,t,g, or c

<400> 676
tcaacgagag cctggccagc ctgccgctcc gcgtcmtcct tctgcccact ctcgctttgg     60
cctggcagct ctatgctcca gagcaccaag tcgccctgga acttcctggg ygatgagttg    120
tacgagcagt cagatgagga gcaggactcg gtgaaggtgg ccctgctgga gaccaacccc    180
tacctgctgg cgctcaccat catcgtgtct atcgttcaca gtgtcttcga gttcctggcc    240
ttcaagaatg atatccagtt ctggaacagc cggcagtccc tggagggcct gtccgtgcgc    300
tccgtcttct tcggcgtttt ccagtcattc gtggtcctcc tctacatcct ggacaacgag    360
accaacttcg tggtccaggt cagcgtcttc attggggtcc tcatcgacct ctggaagatc    420
accaaggtca tggacgtccg gctggaccga gagcacaggg tggcaggaat cttcccccgc    480
ctatccttca aggacaagtc cacgtatatc gagtcctcga ccaaagtgta tgatgatatg    540
gcattccggt acctgtcctg gatcctcttc ccgctcctgg gctgctatgc cgtctacagt    600
cttctgtacc tggagcacaa gggctggtan tcctgggtgc tcakcatgct ctacggcttc    660
ctgctgactt cggcttcatc accatgacgc cccagctctt catcaactac aagctcaagt    720
ctgtggscca mcttccctgg sgcatgtcac taaaaggscc tcaamacatt catcgacgac    780
ctgttcgcct tttggtcatc aangaatggc ccgttaatgg tancggaatc gggct         835

<210> 677
<211> 2697
<212> DNA
<213> Homo sapiens

<400> 677
acaatgagcg tgtgcacaag aggctgagga ctgtggatac ggacagccat gccgagcagg     60
ggccagctca gcagccccag gcccaggtgg aggatgcaga tgcattcgag cacattaaac    120
aaggcagtga cgcatacgat gcacagacct atgatgtggc cagcaaagaa cagcaacagt    180
ctgcaaaaga ctctggcaaa gatcaggaag aggaggagat agaggacacc cttatggaca    240
cagaggagca ggaggagttc aaagcagcag acgtggagca gctgaagcca gaggaaatca    300
agtcgggcac cacagcaccc ttgggctttg atgagatgga agtggagatc caaactgtta    360
aaacagagga agaccaagac cccagaacag acaaagccca taaggagaca gaaaatgaga    420
aaccagaaag aagccgagag tctaccattc atacagctca tcaattcctc atggacacga    480
tcttccagcc ctttttaaaa gatgtcaatg agctaagaca ggagctggag agacagctgg    540
aaatgtggca gccacgtgaa tctggaaacc cagaggagga gaaggttgca gctgagatgt    600
ggcagagtta cctgatctta acagcgcctc tttcacaacg gttatgtgaa gagcttcgtc    660
tcatattaga gcctacccag gcagccaagc tgaaaggaga ctatcgaact gggaaacgac    720
taaacatacg gaaagtcatt ccatacattg ctagtcaatt tcggaaagac aagatttggc    780
ttcgaaggac caagcccagt aaacgccagt atcagatttg tttggctatc gatgactctt    840
ctagtatggt agacaatcat accaagcagc ttgcatttga atctttggct gtgattggaa    900
atgctctaac cctcctggaa gtgggtcaga ttgcagtgtg tagttttgga gaatctgtaa    960
agctgttaca cccatttcat gagcagttca gtgattactc tgggtcccag attctacgtc   1020
tctgcaaatt ccaacaaaag aaaaccaaga ttgctcagtt tctagagtct gttgccaaca   1080
tgtttgcagc tgctcagcag ytctcgcaga acatcagttc agaaactgca caactcctcc   1140
tggtagtctc tgatgggcga ggccttttcc ttgagggcaa agaaagagtc ctggcagcag   1200
ttcaggctgc cggaatgcaa atatctttgt catctttgtt gtattggaca atcccagttc   1260
acgggattct atcttggaca ttaaagtacc gatatttaaa ggacctggag agatgcctga   1320
aatccgatcc tacatggaag agttcccatt cccatactat atcattcttc gagatgtaaa   1380
cgcacttcct gagacactca gcgatgccct cagacagtgg tttgagttgg tgacagcctc   1440
tgaccaccca tagaacagaa agaagagtcc aaagtgagac ttaactgtgg tcagaaggtc   1500
acattgctta cccaggtgct cccttttgga caactacaaa aaattttatt gtaatatttt   1560
tattttacaa cgtgatctta cagcctacag aatgctctct ggctcccggc tttgctgggc   1620
tgaggttttt ataccaaacc tggaagcagc agcaggtgcc tgaactcgta actagagaag   1680
agttatcctt cttccctgcc ttggaagccc tggcctggga ggaggtcata ccccaccgtt   1740
ggagcccagc tgcctgtttt cttttgcagg ggatctgggc acctgtgctt tgaggagatg   1800
ctgccaggag catgggactc tgacagtcct ttgtataaag gactaaaggg agctgccctt   1860
ttgaccctgt tctaagctct gccttgccaa gcccatagtg tgtgcccaaa agctgtcaag   1920
tggccaagac agctcgtttc tggagagtat gagggtgtgt tttcttattg tgaaaggaac   1980
taccttctct tagagggtag gaagaatgtg gtgtgtgtgt gttctcataa agcaactgga   2040
cattataggt gcccaggtca tctataaaaa cgatccttgg gctgtgtaaa aatgaagtgg   2100
cttttcagta tcctctttca cacttgctgc ttcgggagac tatgcaatga tgggaaggtg   2160
attgcccctt tatttcattc agtgccatgg tccctgttgt tgtagtaatt tatttgttta   2220
gttcattttt ttttttctta acagtcaagg ggaagagtga ttcctcacac tgctttcaag   2280
ctggactgag ccagtctcat tctgggaaag aaacgctgtg tccagaactc agcagctcca   2340
tctatttttt ccagtcgaaa gaaactgatc tttaggcagt ttttacttgg ccagaaagca   2400
gtgctgaata cttgaaactg tgtgctctgt tctacttaat gttctgtcag aatgttcttt   2460
tgtaggcagt atgtcatgat gtaatcatct atctccttgt ctgtttccaa gttacactgt   2520
gaagtctgcg acccttttga ggtggtcatc aaagacacag attccttgtt taaccaagtg   2580
tcccaaagca tgtacctgaa gttatatcat tttttattct aaaaagctat gcagcttata   2640
ttctgaaaac tattaaaaca tataccactg ttgttgatgt aaaaaaaaaa aaaaaaa      2697

<210> 678
<211> 734
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (232)
<223> n equals a,t,g, or c

<400> 678
cttttaacag cgcatgcgtg cagtgttgcc tcgcccaaag aagactacaa tctccaggga     60
aacctggggc gtctcgcgca aacgtccata actgaaagta gctaaggcac cccagccgga    120
ggaagtgagc tctcctgggg cgtggttgtt cgtgatcctt gcatctgtta cttagggtca    180
aggcttgggt cttgccccgc agacccttgg gacgacccgg ccccagcgca gntatgaacc    240
tggagcgagt gtccaatgag gagaaattga acctgtgccg gaagtactac ctgggggggt    300
ttgctttcct gccttttctc tggttggtca acatcttctg gttcttccga gaggccttcc    360
ttgtcccagc ctacacagaa cagagccaaa tcaaaggcta tgtctggcgc tcagctgtgg    420
gcttcctctt ctgggtgata gtgctcacct cctggatcac catcttccag atctaccggc    480
cccgctgggg tgcccttggg gactacctct ccttcaccat acccctgggc accccctgac    540
aacttctgca catactgggg ccctgcttat tctcccagga caggctcctt aaagcagagg    600
agcctgtcct gggagcccct tctcaaactc ctaagacttg ttttcatgtc ccacgttctc    660
tgctgacatc ccccaataaa ggaccctaac tttcaaaaaa aaaaaaaaaa aaaaaaaaaa    720
aaaaaaaaaa aaaa                                                      734

<210> 679
<211> 2028
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (91)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2023)
<223> n equals a,t,g, or c

<400> 679
gctgcgcgga gcncngggct gggtctccgc ctcgattctc cgtcctcgcg gcctcccagc     60
ttccagagcc gagctgctgc ccttgactgg ngctcagggg accacagctg caatgacagt    120
ttgggcctgc aaaaagaagg ctggaacaac gggagatgga agctttctgc aaatgcagca    180
ccactggtat ccatgaattt aacctgccca tcattcttcc tagacaagag actattgaaa    240
agtcagggtg ttcaaaatgg cttcagatct tatcaggaca atcttggttg ttgcactaat    300
ttccaaactt ggcacagctg tagatgcaga actgatgcca tctggtgcga ttctacagaa    360
taagagagaa aatttaccca gagtgtgcca tgcactggct tttctgggaa tggcaaggtg    420
ccaggatttg tttttggttc gcttgcaggg gtggaaactt ggaactaggt tccaagatgg    480
tccccgcagc accccacaag aagaaggagg aagcccacag agaaaacggg gcatgccagt    540
tcaaatccac ttccttttaa agagcttcct cagcagccca ataacttttg ccttcatctc    600
attggccaga actgtgtcat tggctactgc tatctgcaag attgtctgag aaatgtagtt    660
tttgtagctg gatatataac tgcctttgac aaaaatccag tttctcttga tgaagaagaa    720
gatggtggtg gatcttggga ggacaactaa cattttatgc cctggctaca gaatacagtt    780
gcagaggagc ataaagttca aaaagatcaa aactctagtt ccttcacaac tgtcaaagct    840
ccaagcagca ctgctcccct ctgacagagt gagcagagtg aaggcatgtc aggtgttctc    900
acaaaactct tgacagggct gacctctctc agtcaatatc cttgtcccac atcaggattt    960
tctagagggc cctgggtacc tgtgcacttc cttggtggcc gtaacctctt tgtggagggt   1020
tggtgtagga taaagaatgt tctattacgc tgctccctca tctgtatcat ttctctcctc   1080
tctaattttc ctgtcagtta tattttggtg gagtctgggt ttgtgtattt gattcctata   1140
gaaagaccat cgctttcatg catggaggag gggaatctac gcaaagaaag gctaccttac   1200
tcctttctgt gactccacca ccagtctagg aatatcctgg gagaagaatt gcctctcaaa   1260
gctgcttcta taagcagcct acatcctagc taagcaaaga agaaacactt cccacatcta   1320
gggctgtcta aaagaacttt ctgtgatgac agaaatgttc tatatctgca gtgtccaata   1380
tggtaaccat ataggcacat gtggctagtg aacacttgaa atgtggctag tgtgactgag   1440
gaaggaaaat ttaaattttg tttaattgta attaatttaa attcagatag ccaaatgggg   1500
ctactagcta ttgtgttaga tagcacggta tactttattc tctttcttgt gttgtagaac   1560
cagctgggag aggtgtgggt cagtcatggg cttggtatcc cctggtcttc actattctag   1620
cttgccattg aatttgtctc ccagaggaaa agaaagaatg gtatttggaa ttaaattcaa   1680
gatgttaact tgacatctat atattgcaca tattcctgta tagtgaatgg atgacctcct   1740
gggaatagtt cctgtgactg attttagtga taattgatca tgaagaaatg gcagtactgc   1800
tccacttcac cttcctagtg actattatgt gttcctagtc agagtgactc agcagagatt   1860
attttgttct cttgtgcaat ttattctgtg tcattttatt tttgtaatat tgtggcagct   1920
aaatgattat tctgtgtatg tttttcaaaa tattaggtgg cttatatttt ttaaaaggct   1980
atgaaataaa aataaactat acgtaamama raaaaaaaaa aantcgag                2028

<210> 680
<211> 639
<212> DNA
<213> Homo sapiens

<400> 680
aattcggcac gagcttcctt ttagggtgac aacaaaaaaa tggaagatgc taaattctac     60
ctgaccctgc ctggaaccaa gatggagatg gaagaaaaag agcttcaagc atctaaaaac    120
ctggtcacct tcaccccaag caaggatagc actaaagaca gctttcagat tgccaccctc    180
atctgctcca caaagctcac ccagaatgtt gacctgttag gcttgttaaa ttggcgttcc    240
aactcccaga acattaaaca caacctaaag aagttaatgg aagtggatgg aggagagatt    300
gttaagtttt tgcaagatac actagatgca ctctttaaca taatgatgga aatgtcagac    360
agtgaamcct atgacttcct tgtgtttgac gcactggtat ttattatttc actgatagga    420
gacaksargt tccagcattt taatcctgta cttgaaacct acatttacaa gcacttcagc    480
gccactttgg catatgtgta agtatgatct gaaggaacta catgttgttg gatctttgga    540
tttgtactct taggactgga ttgttgagaa acgagacgga cctattacta ttcagtaaat    600
acgcctgtta aggcagaact cttattctaa gcttccggg                           639

<210> 681
<211> 1863
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1820)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1830)
<223> n equals a,t,g, or c

<400> 681
ccgaatgaaa ttgccttaag gncttcttcc tatgctgtat ggcagaagag ttcatggttg     60
cattcaggga ttgcaaggac catatagaca tgtcacaggt ggaawaaggg ccacwagccg    120
ttttgcacaa atgcctgmcc acctgcccct cttccatcca ggagtgtgtt actgaggggc    180
tggctggacc aacctgctgg ctcaggcatg tgactggcct aactgcatgc ccagggcact    240
gccagggttc aatgggccag ccgtctccta ctccaccttg gatttttctc tccatcacat    300
catttctgac catttgctcc cttccattct tgaaacacct catgccccac aggagcccca    360
gtggtgactg gatctgcaag ggttatctcc cgccctctgg ggtttgagtg gaggtatgga    420
gccagagagg ctatcctagc taccttcctc ctagggggag ctggtcccct tcctatgtgg    480
tagagagact ggtgtaagag tgtgggtgtg gcaggcgccg gaaatcctca aagctttcag    540
aagcatccag aatgcctacc atcagctcct gaatcaggga ttttcagcac tacctctgag    600
ccatggggtt ggctgcccag ccaggcttcc aggccctgag gacatgtggt caggttcagc    660
aggctcctgg gtaaagaggg tgggaggggg cttctccttt tggaagcaga tagccatgca    720
ggtagaattg tcatctccca agtggccaca tacagcaacc cactccaggc catggggacc    780
accactcagg gttcggggct ggcaggaggg tagtttctcc agtctcccca gtctgttggt    840
gtctttatag gaaactataa agcagagcag tggtgtcttt agaggaaact cattcaagtc    900
agggcactga ttttcctctc agtttattat ttggggggat agggtcaggt gggtatagta    960
gtactttacc agggtgcttt taagttactt taaaaaaagc ctacaaaata ttttttttct   1020
tttatttgct cgagttcaca ttaatgatgg tcacaaggct gccttgttgg gcaggcgtat   1080
tgcccccagt tcctcttctg ctggcctgta tgacctccac agccaggccc tgggcccaag   1140
ccccttgtcc cttctccact gcccctcttt ccagacagta aaggccatgg tcagtgtgtt   1200
tttctcttgt aaacaaaccc cagcttgttt aacagaaatg ctaataacct actgggaaag   1260
atggaggtct aaattacctc cagggttttt ctgggggttt atcaccagtg tgggtccctt   1320
ctgataccac caggttcact ccaggcagag tggggcggaa ggctgctgag gatatgggtc   1380
agttacagca gccctcacct caaagggctg gcctgcttct cagcctacat tcatttgcaa   1440
gcttcaatct ctggaccatc tggtgttcac aggtgttaga gggttagggg ttaggggcca   1500
gttttggatt tgattcatag gtaggagggc ttagatttta aggcacttct gaaagtcaat   1560
ccctggacaa ggcagtcatc acataagaac agctaccttc tccacttggt ggcacaagag   1620
gtagggaggg gagtatgggt tcatttggct tcgcattatg caaggtgaaa ccgtttgttt   1680
tccctctcca ttttccctaa ctaaatgaaa aggacacatt ctgaaatccc ttttgttgga   1740
gaataagtca gtctgarggg aaatgggagg ccagagatga gaaacccttt grrgaagatt   1800
ktammattac tgtttttgan gaatttcccn tagaagtttt ccccttagaa gtttccctac   1860
ttt                                                                 1863

<210> 682
<211> 918
<212> DNA
<213> Homo sapiens

<400> 682
ggcgcccggc ctgcaaactt ttttgtaggt atttctggta aacaaatcct taggttatct     60
ttgctgtggt tgtggtttgg ctttagtcat gatttcaaag tagaaatagc taggcattat    120
tttttgaaat atatgaccta tatgtagtca agaatccact gaacagaggg aagcaaacct    180
tttggaaact ggcttttggg cagacagtaa acgtccagtt tgatgctgga agcatgaaca    240
gcttcatcag gtaggtactc ctcaactctg atgagtttgt cctttcagcc taagggggtg    300
gaagggagtt gtttgagaat agcaaatacg catgttgatt gcgagtgtgt ggagacaaag    360
gcagttccca ccacagttag gtcctggccr ttgtttcctc gcctgcgatg ctccttgtac    420
rtcctcaccc tcctctcccg cctctgcctt ctgctgggtc aaaggtggcc tttttctctc    480
cagccttgaa ttgttccctg ttggcttccc aagggcccat ctgctggtac agtccacact    540
tccamagcca agacccgaga gggctttcac tgccccaagc ctctctcctg tgaccttggg    600
attctgtctt ggcagaatcc tttgtcagcg gctcttrctc tgtccttcct gtttggccac    660
agctctttca atcaatgggt attctagaac cgcaggatgt cagagctgga agggacgcga    720
taccggttta cacaagggga aactcctcga ggctctggga gggacggagg gttttggtga    780
cagagcgaga gctaaaattg aggattcctg aatccagatc ttgcctccca tcagccatct    840
ttctcccaat aaatttttgt tttgtgcaag gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa    900
aaaaaaaaaa aaaaaaaa                                                  918

<210> 683
<211> 1123
<212> DNA
<213> Homo sapiens

<400> 683
ccgcgcaagc ttaaagcctc cagccggacc tcggctctgc tctccggctt cgccatggtg     60
gcaatggtgg aggtgcagct ggacgctgac cacgactacc caccggggct gctcatcgcc    120
ttcagtgcct gcaccacagt gctggtggct gtgcacctgt ttgcgctcat gatcagcacc    180
tgcatcctgc ccaacatcga ggcggtgagc aacgtgcaca atctcaactc ggtcaaggag    240
tccccccatg agcgcatgca ccgccacatc gagctggcct gggccttctc caccgtcatc    300
ggcacgctgc tcttcctagc tgaggtggtg ctgctctgct gggtcaagtt cttgcccctc    360
aagaagcagc caggccagcc aaggcccacc agcaagcccc ccgccagtgg cgcacagcca    420
acgtcagcac cagcggcatc accccgggcc aggcagctgc catcgcctcg accaccatca    480
tggtgccctt cggcctgatc tttatcgtct tcgccgtcca cttctaccgc tcactggtta    540
gccataagac tgaccgacag ttccaggagc tcaacgagct ggcggagttt gcccgcttac    600
aggaccagct ggaccacaga ggggaccacc ccctgacgcc cggcagccac tatgcctagg    660
cccatgtggt ctgggccctt ccagtgcttt ggccttacgc ccttcccctt gaccttgtcc    720
tgccccagcc tcacggacag cctgcgcagg gggctgggct tcagcaaggg gcagagcrtg    780
gagggaagag gatttttata agagaaattt ctgcactttg aaactgtcct ctaagagaat    840
aagcatttcc tgttcttcca gctccaggtc cacctcctgt tgggaggcgg tggggggcca    900
aagtggggcc acacactcgc tgtgtcccct ctcctcccct gtgccagtgc cacctgggtg    960
cctcctcctg tcctgtccgt ctcaacctcc ctcccgtcca gcattgagtg tgtacatgtg   1020
tgtgtgacac ataaatatac tcataaggac aaaaaaaaaa aaaaaaaaaa aaaaaaaaac   1080
tcgagggggg gcccgtaccc aatcgcctgt gatgcatcgt ata                     1123

<210> 684
<211> 731
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (672)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (676)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<400> 684
cgcggaggct ggagctggag gcgcggcgcc gsntgagctg agaaccatgt gtgctcagta     60
ttgcatctcc tttgctgatg ttgaaaaagc tcatatcaac attcgagatt ctatccacct    120
cacaccagtg ctaacaagct ccattttgaa tcaactaaca gggcgcaatc ttttcttcaa    180
atgtgaactc ttccagaaaa caggatcttt taagattcgt ggtgctctca atgccgtcag    240
aagcttggtt cctgatgctt tagaaaggaa gccgaaagct gttgttactc acagcagtgg    300
aaaccatggc caggctctca cctatgctgc caaattggaa ggaattcctg cttatattgt    360
ggtgccccag acagctccag actgtaaaaa acttgcaata caagcctacg gagcgtcaat    420
tgtatactgt gaacctagtg atgagtccag agaaaatgtt gcaaaaagag ttacagaaga    480
aacagaaggc atcatggtac atcccaacca ggagcctgca gtgatagctg gacaagggac    540
aattgccctg gaagtgctga accaggttcc tttggtggat gcactggtgg tacctgtrgg    600
tggaggaggn atgcttgctg gaatagcaat tacagttaag gctctgaaac ctagtgtgaa    660
ggtatatgct gntgancctc aaatgcagat gactgtacca gtccaagctg aaggggnact    720
tatgccaatt g                                                         731

<210> 685
<211> 1568
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (44)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1428)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1451)
<223> n equals a,t,g, or c

<400> 685
ggcagagcta gtgtggactc catccccctg gagtgggatc acgnctatga cctcagtcgg     60
gacctggagt ctgcaatgtc cagagctctg ccctctgagg atgaagaagg tcaggatgac    120
aaagatttct acctccgggg agctgttgsc ttatcagggg accacagtgc cctagagtca    180
cagatccgac aactgggcaa agcctggatg atagccgctt tcagatacag caaaccgaaa    240
atatcattcg cagcaaaact cccacggggc cggagctaga caccagctac aaaggctaca    300
tgaaactgct gggcgaatgc agtagcagta tagactccgt gaagagactg gagcacaaac    360
tgaaggagga agaggagagc cttcctggct ttgttaacct gcatagtacc gaaacccaaa    420
cggctggtgt gattgaccga tgggagcttc tccaggccca ggcattgagc aaggagttga    480
ggatgaagca gaacctccag aagtggcagc agtttaactc agacttgaac agcatctggg    540
cctggctggg ggacacggag gaggagttgg aacagctcca gcgtctggaa ctcagcactg    600
acatccagac catcgagctc cagatcaaaa agctcaagga gctccagaaa gctgtggacc    660
accgcaaagc catcatcctc tccatcaatc tctgcagccc tgagttcacc caggctgaca    720
gcaaggagag ccgggacctg caggatcgct tgtcgcagat gaatgggcgc tgggaccgag    780
tgtgctctct gctggaggag tggcggggcc tgctgcagga tgccctgatg cagtgccagg    840
gtttccatga aatgagccat ggtttgcttc ttatgctgga gaacattgac agaaggaaaa    900
atgaaattgt ccctattgat tctaaccttg atgcagagat acttcaggac catcacaaac    960
agcttatgca aataaagcat gagctgttgg aatcccaact cagagtagcc tctttgcaag   1020
acatgtcttg ccaactactg gtgaatgctg aaggaacaga ctgtttagaa gccaaagaaa   1080
aagtccatgt tattggaaat cggctcaaac ttctcttgaa ggaggtcagt cgtcatatca   1140
aggaactgga gaagttatta gacgtgtcaa gtagtcagca ggatttgtct tcctggtctt   1200
ctgctgatga actggacacc tcagggtctg tgagtcccac atcaggaagg agcaccccaa   1260
acagacagaa aacgccacga ggcaagtgta gtctctcaca gcctggaccc tctgtcagca   1320
gtccacatag caggtccaca aaaggtggct ccgattcctc cctttctgag ccagggccag   1380
gtcggtccgg ccgcggcttc ctgttcagag tcctccgagc agctcttncc cttcagcttc   1440
tcctgcttct nctcatcggg cttgcctgcc ttgtaccaat gtcagaggaa gactacagct   1500
gtgccctttc aacaactttt gccggcattc cacccatgct cagatacacg aatggcctct   1560
cactctga                                                            1568

<210> 686
<211> 899
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (837)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (839)
<223> n equals a,t,g, or c

<400> 686
gaatttgtaa atgaacagtc caatatttcc tctcggctca ttttgcacat ccatttttgg     60
ggaaatgtga tttctctctc tttttttttt tttttttgcc taaggcacaa tctcaagagg    120
tcctgagacc acgtacccat gatttttttc ttgctctgtg atacccaata actccttcac    180
ctaagccctg ttgttgattt tgaagtgctt cctaggccag tgattttagc ttctgccagc    240
tgcttttgcc agtagattaa cgtgttttta tttttcaaac tccgtgtttc ctaacgtgga    300
gtgtatgggt ctaagagagc ctgctgtcct ccctgccttc caccttggag aggaggctgg    360
acgcatcagc agtggccagg gcaggtcgca aaatctccca gcctagagac cacacctgaa    420
acggctgaag ccagcttgca caagggctgc tgtccctctg cggcaggcag agctggtggg    480
ggcaggggtc acagagcagt catagacacc atggaccagg gcaggagaag ggcagatggc    540
acatgggcac aacagggcct tgtccttaga gcactggggg gtcatggctg ggaggggcat    600
ggcaggggct ggcatccctg tagagccaga ggggccaccc agggcagtga cattccagat    660
atgttgggct cacctcatcc ttgctgtgag actggagttc catggggaca tgaagtcagt    720
acaccgcaga gctgctcagc tgctctacct ctcgctgact tttttgttgc acatatacat    780
tttctttcaa ttagcattta tttcagcttt tatttaagct ttttgacagt acatgtnana    840
tatatgatta taaccattta aaaataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaac     899

<210> 687
<211> 1001
<212> DNA
<213> Homo sapiens

<400> 687
gctcgtggcg ctggaccgca tggagtacgg gggcaccttc cgcaagcgcg aggacctgcg     60
cggccgcctg ttttgggtgg cgctggacct gctggacctg ctggacatgc aggccagcct    120
gtgggagccg ccgcgctccg ggctgccgct gtgggccgag ggcctcacct tcttctactg    180
ctacatgctg ctgctggtgc tgccgtgcgt ggcgctcagc gaggtcagca tgcagggcga    240
gcacatagcg ccgcagaaga tgatgctgta cccggtgctc agcctcgcca ccgtcaatgt    300
ggtggccgtg ctggcgcgcg ccgccaacat ggcgctgttc cgggacagcc gtgtctcggc    360
catcttcgtc ggcaaaaacg tggtggcgct cgccaccaag gcctgcacct tcctggagta    420
ccgccgccag gtgcgcgact tcccgccgct tgcgctatca ctggagctgc agccgccacc    480
cccgcagcgc aactcggtgc cgctcgccgc cgccgctgca cggcccgcct gggcgccccc    540
acatgtcctc gcccacgcgt gaccccctgg acacgtgaca gggcccgcgc ggcccccgac    600
acgcccctgg ggcgcagaga caccgggttg gcttggggcg cgcggtttgc atgggatggg    660
gtgggggcgg gctcccctag ggacaggtgc ctcgagtgcc cgtgcctggg gtcccgcggt    720
cgcttcttca tctcaggaat ctctcggacc gcggatcctc agcccccgct ccaccagccc    780
gccccagggc gtgggtctgt ttgggaggcc tgggccggag cagagcagag gtgatccggc    840
ccctgcctgc tgggccgccc gggttggaag ggagggcagt gtgggcggag atctgctcct    900
tcggtggggg cctctggctc agatttgggg ccaaggaggc ctctgtcatt ttaaagactc    960
gtgtttacag ttttgtaaaa aaaaaaaaaa aaaaaaaaaa a                       1001

<210> 688
<211> 1156
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (47)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (351)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (397)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (432)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (792)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1119)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1156)
<223> n equals a,t,g, or c

<400> 688
aattcggcac agttcaggcg ccanagctgg ccgatcggcg ttggccnccg acatgacgcc     60
cgaggaccca gaggaaaccc agccgcttct ggggcctcct ggcggcargt ctacatctcc    120
gaaatcrcct acccagcagt ccgggggttg ctcggctcct gtgtgcagct aatggtcgtc    180
gtcggcatcc tcctggccta cctggcaggc tgggtgctgg agtggcgctg gctggctgtg    240
ctgggctgcg tgcccccctc cctcatgctg cttctcatgt gcttcatgcc cgagaccccg    300
cgcttcctgc tgactcagca caggcgccag gaggccatgg ccgccctgcg nttcctgtgg    360
ggctccgagc agggctggga agaccccccc atcgggnctg agcagagctt tcacctggcc    420
ctgctgcggc ancccggcat ctacaagccc ttcatcatcg gcgtctccct gatggccttc    480
cagcagctgt cgggggtcaa cgccgtcatg ttctatgcag agaccatctt tgaagaggcc    540
aagttcaagg acagcagcct ggcctcggtc gtcgtgggtg tcatccaggt gctgttcaca    600
gctgtggcgg ctctcatcat ggacagagca gggcggaggc tgctcctggt cttgtcaggt    660
gtggtcatgg tgttcagcac gagtgccttc ggcgcctact tcaagctgac ccagggtggc    720
cctggcaact cctcgcacgt ggccatctcg gcgcctgtct ctgcacagcc tgttgatgcc    780
agcgtggggc tngcctggct ggccgtgggc agcatgtgcc tcttcatcgc cggctttgcg    840
gtgggctggg ggcccatccc ctggctcctc atgtcagaga tcttccctyt gcatgtcaag    900
ggcgtggcga caggcawytg cgtcctcamc aactggctca tggsctttct ygkgaccaag    960
gagttcagca gcctcatgga ggtcctcagg ccctatggag ccttctggct tgcctccgct   1020
ttctgcatct tcagtgtcct tttcactttg gtctgtgccc tgaaactaaa ggaaagactc   1080
tggaacaaat cacagcccat tttgaggggc gatgacagnc actcacttag gggaatggag   1140
caagccttgt gacttn                                                   1156

<210> 689
<211> 695
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (25)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (689)
<223> n equals a,t,g, or c

<400> 689
ccggcgatgt ctctgtctgt ttggntcatc agttccgaat cacgccacca acagccccgc     60
aatggcgctg ctgatcccaa ccggtctgca tcaggtacta acaccatcgc ctggttccag    120
attggtkaat tcaccaacgc ggcgggtacg gttttccacg gtgacattaa ccgcttctat    180
gccggtgacg accgcgggga tgttcatgtc cggcttcttc ccgatcatga tgttcggtct    240
gccgggtgcg gcgctggcga tgtacttcgc agcaccgaaa gagcgtcgtc cgatggttgg    300
cggtatgctg ctttctgttg ctgttamtgc gttcctgacc ggtgtgactg agccgctgga    360
attcctgttc atgttccttg ctccgctgct gtacctcctg cacgcactgc tgaccggtat    420
cagcctgttt gtggcaacgc tgctgggtat ccacgcgggy ttctctttct ctgcgggggc    480
tatcgactac gcgttgatgt ataacctgcc ggccgccagc cagaacgtct ggatgctgct    540
ggtgatgggc gttatcttct tcgctatcta cttcgtggtg ttcagtttgg ttatccgcat    600
gttcaacctg aaaacgccgg gtcgtgaaga taaagaagac gagatcgtta ctgaagaagc    660
caacagcaac actgaagaag gtctgactna actgg                               695

<210> 690
<211> 594
<212> DNA
<213> Homo sapiens

<400> 690
tcaggcctca tctcatgcag cagtcagttg aatacgaaag gaagaagttt caagagattt     60
tggagaggca accaaattcc ctggactttg tcacccagtg gctggaagaa gcctcagagg    120
accttatgac tcagaagtat aaacacgccc tgccagtggg gggaatggct gctggctctg    180
gggacatgcc caggctgagc cctgttgctg tccagaatta cgcttacctg aagcttctga    240
agtgggacca cctccagagg ccrttccccg aaacagtttt aatggaccag tctcgcttcc    300
acgagctcca gttgcagctg gaacaactga ccatcctggg ggctgtgttg ctggtcacct    360
tcagcatggc agcgccagga atttccagcc aggccgactt tgctgagaaa ctcaagatga    420
ttgtgaagat tttgctaaca gatatgcacc tgccctcctt ccatctgaag gacgtcctca    480
ctaccatcgg ggagaaggtg tgcctggagg tgagcagctg cctctccctg tgtgggtcct    540
ctcccttcac cacggacaag gagaccgtgc tcaagggcca gatccacgcc gagc          594

<210> 691
<211> 1296
<212> DNA
<213> Homo sapiens

<400> 691
cttcatcagc tgcgacctcc tcaccgcttt cctcttatac cgcctgctgc tgctgaaggg     60
gctggggcgc cgccaggttg tggctactgt gtcttttggc ttcttaaccc cctgcctatg    120
gcaktatcca gccgcggtaa tgcggactct attgtcgcct ccctggtcct gatggtcctc    180
tacttgataa agaaaagact cgtcgcgtgt gcagctgtat tctatggttt cgyggtgcat    240
atgaagatat atccagtgac ttacatcctt cccataaccc tccacctgct tccagatcgc    300
gacaatgaca aaagcctccg tcaattccgg tacactttcc aggcttgttt gtacgagctc    360
ctgaaaaagc tgtgtaatcg ggctgtgctg ctgtttgtag cagttgctgg actcacgttt    420
tttgccctga gctttggttt ttactatgag tacggctggg aatttttgga acacacctac    480
ttttatcacc tgactaggcg ggatatccgt cacaactttt ctccgtactt ctacatgctg    540
tatttgactg cagagagcaa gtggagtttt tccctgggaa ttgctgcatt cctgccacag    600
ctcatcttgc tttcagctgt gtctttcgcc tattacagag acctcgtttt ttgttgtttt    660
cttcatacgt ccatttttgt gacttttaac aaagtctgca cctcccagta ctttctttgg    720
gtacctctgg cttactgcct cttgtgatgc cactagtcag aatgccttgg aaaagagctg    780
tagttctcct aatgttatgg tttatagggc aggccatgtg gctggctcct gcctatgttc    840
tagagtttca aggaaagaac acctttctgt ttatttggtt agctggtttg ttctttcttc    900
ttatcaattg ttccatcctg attcaaatta tttcccatta caaagaagaa cccctgacag    960
agagaatcaa atatgactag tgtatgttcc acaccctctg ctactgtgtt acattctgat   1020
tgtcttgtat ggaccagaag agagctttgg gacatttttt ctgaacattc taagcattct   1080
agtgaaagtt cccatgttcc aacagaactt aaaagcaatg tttgccttat atataaaagg   1140
gacacaataa ttgaggtcca ccttctagga aatcctagga ctcgtttatt tgggacatgg   1200
tgggaataaa ggtcacatat tggaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1260
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                             1296

<210> 692
<211> 906
<212> DNA
<213> Homo sapiens

<400> 692
gaacaaatac agatgagacc tccatcagct ttttcttcct attgccacaa atgcctattg     60
gcgagggttg gttggtatgg tctggaactt cacagtactg taagacgggt tctgcaggat    120
gacaggctta ggacaaggcg agagggaatc ccctgtacca tgctggcatc acaatggact    180
tttccagaaa ccaaatccat aatatccaaa ctaatggcag ttttggtgtt tggttccctg    240
gcaccagtta ctctgggagc agatgaagac agatgtctct tgcttgtgtg ggagagcata    300
tgccacccca aaatatgcct caacagcata aggattattt tgagaaactg cagctacagg    360
agaaactctg aaaacagagt ataccagttt ttgagggaaa ttgacatcta taaaggaaat    420
ctccacttgt gagagtgttt ccctctccgt accaaaagag aaggatgact aaatcagagg    480
aaactattat caatggagaa ggcacctact gaaatctgca taacaaacat tactcttatt    540
taccatactt gtcctgktca cctccccata actggcttcg cccacaatct tctctgkttt    600
tagktgaaaa tgctttagaa gctggagttc tagatcacct ctttcagaat tactcawttt    660
cccctgggta tctcctatgk atacmtgaag catacatgtt aacaaacttc tgcttgtttt    720
tcttttgtta ccctgttggt ttgttatagt ggttccaacc cagaaattag aagggtagag    780
ggaaaatgat tttttttctc ccctccactt gaaatatgta tcttcctgct ctatgaagtt    840
gtttggatgt cattaactca ccactctcaa atacataatt agttctgcct acaaaaaaaa    900
aaaaaa                                                               906

<210> 693
<211> 1225
<212> DNA
<213> Homo sapiens

<400> 693
ggcacgaggc ctgggggaga gtggatccag gtgaaggggg cagaggttac ctgtgcaggg     60
atcagtccat ttattcctat tttctctgac agctggatga aagggactgg gagttttcgt    120
cctcttgaat aagaactcga caacagagtg ggaactttct gtcttgtgat ccattgcctg    180
gctttctgta tttgtctgaa tgctttcacg ggagtgtgtc gcactggagc acagaggaca    240
ctcgatcgtg cggcgcgcag ggcggggggc cgccgctgcc tccccgcggg atggctggca    300
ctgtgctcgg agtcggtgcg ggcgtgttca tcttagccct gctctgggtg gcagtgctgc    360
tgctgtgtgt gctgctgtcc agagcctccg gggcggcgag gttctctgtc atttttttat    420
tcttcggtgc tgtgatcatc acatcagttc tgttgctttt cccgcgagct ggtgaattcc    480
cagccccaga agtggaagtt aagattgtgg atgacttttt cattggccgc tatgtcctgc    540
tggctttcct tagtgccatc ttccttggag gcctcttctt ggttttaatc cattatgttc    600
tggagccgat ctatgccaaa ccactgcact cctactgacc actcttcagg aaaacgaaaa    660
cctgttctct ccttcattgt gatgacattg atgagcagga aggcactatt cagagccttg    720
ttttgacagc cctcatgcct taaggttaga ggagtatctg tccatcacta agacaaatct    780
ctggagtcct ggcttccaga aacaggattg ccaaattgtc cctgtggggc tagattctta    840
ccagcttaag aaggatattg ctatcttctt agtacccgta ccttaggatt tccaactgtt    900
ttgaaaggga aatagtaaca gtgatctgct tagagtggat tttcactcaa gtccttagta    960
agtggatttt ggggaaaaaa gcacatgggc ttctggttct ttttgataat atataaaatt   1020
attcattatg aggttgcagt tgtttgcaaa ggagaggcac tcaaatttga aaggttattt   1080
taatgtgata atttggaaga cttactcaga tgttggtcat tgaccactct gtgcatatat   1140
ttctgcagag ctctgtgaag gcaatgagtg tcacttccct ctgctctaat aaagcaataa   1200
ataataaaaa aaaaaaaaaa aaaaa                                         1225

<210> 694
<211> 1852
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1836)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1842)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1848)
<223> n equals a,t,g, or c

<400> 694
attttgtgcc acttaaaaaa tttgatactg gtgatggaat gtttctccag tgggttcttt     60
gtgctgccat atgttggttg ccttggttgt caatctgata ttacattgtc caaagttttg    120
gccttttgca atgcttgggg gctgcatttg ggcaacaggg aacattgctg ttgtcccaat    180
tatcaaaacc attggtttag gccttggaat cttaatctgg ggatcattta atgccttaac    240
tggctgggca agctcaaggt ttggctggtt tggattggat gcagaagaag tatcaaatcc    300
gctgctaaat tacattggag ctgggctatc agtacgtaag tgctttcata ttttgtycat    360
caaaagtgaa ataccaaata acacgtgttc catggatacc actccattaa taacagagca    420
tgtgatcaac acaacccaag acccctgttc ctgggtggat aaactttcta cagtacacca    480
ccgcatagtg ggctgcagtc ttgcagtgat atctggagta ctctatggat ctacatttgt    540
gccaatcatc tacatcaagg accacagcaa aagaaatgat agtatatatg caggggcaag    600
ccaatatgat ttagactatg tgtttgcgca cttcagtggc atctttctta caagtactgt    660
ctactttctg gcctactgca tagccatgaa aaatagtcct aaactatatc ctgaagcagt    720
cctaccagga ttcctgtcag gagtactttg ggctatagct acctgctgtt ggttcatagc    780
aaatcactct ctgagtgctg tggtcagttt tccaataatc actgctggtc caggatttat    840
agctgcaatg tggggtatct tcatgtttaa ggaaataaag ggtctacaaa actacctatt    900
aatgatactt gcattttgca tcatcttgac tggagcctta tgcactgctt tttctaaaat    960
ctaacaatga caaaaccagc aggtggcagc agtagttaag agaacgcgtc tatcggacag   1020
cggagagatc atgctgagaa aagagtgcat tttcatatag caaatggatc tcagccactg   1080
ttggagtggg taaatgattt ttttccccaa aaatgtgaga atgaaggaag attgagtttc   1140
attcaagtat aaaaatgaaa atttcttctg atgaactgtt tatgaaggta gtactttact   1200
gggtgactaa aatgtctaca ttattatagc attacatacg aggatgctct ttttaccaca   1260
gtatgtacct agtgttgcat aatctagaac acagtataga gtccatatac aaagaagtta   1320
cagyccatat ttctcaccta ttaccccagt gaagtgaggc agaaatacct tgggcgagga   1380
gggagagcct taccttctaa tggaattaga ttccaaagat atttggatcc tttgtttcat   1440
aaagtaaatg catagttggt aactaaatgt taaaaaggcc attttattat tgttagccaa   1500
aacttctgtt tatttcaagt taatatcgcc caactctaca tcatctaccc attttagctc   1560
ataatgcttt tgattatcgc cagataaagt ccattctcag agaacaaaaa tttttcatca   1620
ttgagaaaat gtgcataaca taatacatac atacacaagt atattcacgt acataaatac   1680
acacagatat gttgctaaag tgagattgta ggttatcagt aacaatttaa aggaaacaac   1740
cactcttttg aatgtacaas ttttttttct gaaatacact tttctaaaac cctcttaacg   1800
gaggtttccg ttttcttcyt gttttaacgg tggttnccat angcaaanga aa           1852

<210> 695
<211> 2028
<212> DNA
<213> Homo sapiens

<400> 695
tttttttttt tttttttttt ttttgtgttt cattttctgt ttattacttg aaatcacggt     60
gctcgtgtag gttttttttt tttttttcaa ttttatgttt tcatacatga aactcacgcc    120
aggtgccggg acccccacag cccgaccccc cgagggcggg taatgctttc ttgggcagcc    180
cttaccgggc agagggtggc gagccggttc ctgcctggag gttccaccct caaccagtgg    240
aggcacagac gttatttaaa aatcgttaaa aaacaaaaca gaacacacat ttaaataggt    300
atccaagaca gttcttcaaa aaacaaaccc gcccctttta ctcctttttt ttctattttt    360
ttttcttttt tttttggaaa aatgaaaaca aaacaaaacc caaaatcctt gagctctacc    420
ctctgggacc cctccctgcc caccctccca caaaaaaatt tacagcgcta cagttataac    480
acgtgatgtt cacatctgaa accattaact ttcaacacat aaaggggggg agttgaggac    540
ctggggttca cctacgagaa caacggtggg ggacaggcag agccaggaca agaccgacag    600
gtggggtgag gaagggtcca gacatctcca ttatcattaa aaaataaaaa gtgagtgggg    660
aaaaaaatcc aaaaactacc ccattgaaat ggccccagta ggggatttgt ccctcccctc    720
tggagacaga cacccctagg gcaggggcac tgagaggcag ggggtccaaa ttagaccagc    780
agcggacccc gccacggggg ttaatgctac acggagttgt cgccccctgc ccaggggatt    840
cacagctcag caccccctcc catcctcgct gcaggagggr cccccagaca gtcccaaatc    900
cacatccctc aggttgggcc gggaaggagg gctcggaggg gggaactccc cagcacccag    960
ccattctctc ccctttttca agagttcccc aaccactatt ggctcagtca gaaaattaat   1020
agtctataaa taccccaaac tcaggcagga ggtcagaaaa cacgggagtg ggggcggagg   1080
aaacagcaca gtccgccggc tggggcgggg cggagggcag gctggggggg tagttcccct   1140
ctcccttccc gacaggaaag ggtgccatgc ccctgcaccc aaaccccatg gggacctcag   1200
ccccagcctc tgctaaaaca gctttgctct ccttgttaaa gaaatgaagg raaatgcaaa   1260
aaaaagatca agaaaagagg ataggagtgg aagagaaaca gtcccctcgt tggcttctgt   1320
gacctgttgg cttgctgtag cccagtgggc gctgctggcc tggggtggag accccgaagt   1380
ctgcactggg gggtggggtg ggttctgcgc actgcggccc ctcccctcat ctgtaaagtg   1440
cataatgaca tatcgacatt tttgacttaa aacctgaata gggtcggggg ggaaaggagg   1500
cggcggaagg gatggggcgc gtttctccgt ctccttcact ctccgccatc cagagagact   1560
gctacatatt ggagctgggg aaggttggca gggaggaccg acctggcgca gaggtgaaag   1620
gagacagacg gaggaggmgg aggaggagga agaggagggc aggagtgaag ggtgaaggag   1680
gtaggaagca aagcccatga agagtccagg aaaccacggt cagaactttt taaaaaaaga   1740
aaaaaataat aaaaaagaag aaaagaaaaa aagacttctg gctgggggag tggccgcctg   1800
ccctccaggg ctgggccacg ttctctccgg ggctctcgga gtccccgccg ccctgggctg   1860
gggtgcgagg ggcgagggtg gccgatccga agatcctaag ccaccacgaa ctctgacttg   1920
atgtcagggt tgacttctgg cttccacacg gagtcctcga agtcgaggcc caagccggag   1980
gcctcgctgg gtgccgccgc ccccgctgct actgcgctct gccgaatt                2028

<210> 696
<211> 556
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (402)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (473)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (536)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (541)
<223> n equals a,t,g, or c

<400> 696
gaattcggca cgagcagctc caatatgtag cagtctctct ggatggcgga gagtgaagga     60
gacggagaaa cgcgccccat cccttccgcc gcctcctttc ccccccgacc ctattcaggt    120
tttaagtcaa aaatgtcgat atgtcattat gcactccccc agccagaagt ctttttttct    180
tttcttcttt tttattattt ttttcttttt ttaaaaagtt ctgaccgtgg tttcctggac    240
tcttcatggg ctttgcttcc tacctccttc acccttcact cctgccctcc tcttcctcct    300
cctcctcctc ctccgtctgt ctcctttcac ctctgcgcca ggtcggtcct ccctgccaaa    360
cttcccccca gtggcagaat tcggggtctc caaccccagg cnagcaagcg gcccactggg    420
gctacagcaa agcccaacaa ggtcacaaga aagcccaaac ggagggggga ctngtttcct    480
ctttccaact tcctaatcct ctttttcctt gaatcttttt ttttgcattt tccttncatt    540
ntcttttaaa caaagg                                                    556

<210> 697
<211> 1873
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (630)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1787)
<223> n equals a,t,g, or c

<400> 697
tcgttatcaa caaccaggtt ggtttcacca cctctaatcc gctggatgcc cgttctacgc     60
cgtactgtac tgatatcggt aagatggttc aggccccgat tttccacgtt aacgcggacg    120
atccggaagc cgttgccttt gtgacccgtc tggcgctcga tttccgtaac acctttaaac    180
gtgatgtctt catcgacctg gtgtgctacc gccgtcacgg ccacaacgaa gccgacgagc    240
cgagcgcaac ccarccgctg atgtatcaga aaatcaaaaa acatccgaca ccgcgcaaaa    300
tctacgctga caagctggag caggaaaaag tggcgacgct ggaagatgcc accgagatgg    360
ttaacctgta ccgcgatgcg ctggatgctg gcgattgcgt agtggcagag tggcgtccga    420
tgaacatgca ctctttcacc tggtcgccgt acctcaacca cgaatgggac gaagagtacc    480
cgaacaaagt tgagatgaag cgcctgcagg agctggcgaa acgcatcagc acggtgccgg    540
aagcagttga aatgcagtct cgcgttgcca agatttatgg cgatcgccag gcgatggctg    600
ccggtgagaa actgttcgac tgggscggtn cggaaaacct cgcttacgcc acgctggttg    660
atgaaggcat tccggttcgc ctgtcgggtg aagactccgg tcgcggtacc ttcttccacc    720
gccacgcggt gatccacaac cagtctaacg gttccactta cacgccgctg caacatatcc    780
ataacgggca gggcgcgttc cgtgtctggg actccgtact gtctgaagaa gcagtgctgg    840
cgtttgaata tggttatgcc accgcagaac cacgcactct gaccatctgg gaagcgcagt    900
tcggtgactt cgccaacggt gcgcaggtgg ttatcgacca gttcatctcc tctggcgaac    960
agaaatgggg ccggatgtgt ggtctggtga tgttgctgcc gcacggttac gaagggcagg   1020
ggccggagca ctcctccgcg cgtctggaac gttatctgca actttgtgct gagcaaaaca   1080
tgcaggtttg cgtaccgtct accccggcac aggtttacca catgctgcgt cgtcaggckt   1140
gcgcgggatg cgtcgtccgc tggtcgtgat gtcgccgaaa tccctgctgc gtcatccgct   1200
ggcggtttcc agcctcgaag aactggcgaa cggcaccttc ctgccagcca tcggtgaaat   1260
cgacgagctt gatccgaagg rcgtgaaagc gcgtagtgat gtgttctggt aaggtttatt   1320
acgacctgct ggaacagcgt cgtaagaaca atcaacacga tgtcgccatt gtgcgtatcg   1380
agcaactcta cccgttcccg cataaagcga tgcaggaagt gttgcagcag tttgctcacg   1440
tcaaggattt tgtctggtgc caggaagagc cgctcaacca gggcgcatgg tactgcagcc   1500
agcatcattt ccgtgaagtg attccgtttg gggcttctct gcgttatgca ggccgcccgg   1560
cctccgcctc tccggcggta gggtatatgt ccgttcacca gaaacagcaa caagatctgg   1620
ttaatgacgc gctgaacgtc gaataaataa aggatacaca atgagtagcg tagatattct   1680
ggtccctgac ctgcctgaat ccgtagccga tgccaccgtc gcaacctggc attaaaaacc   1740
cggcgacgca gtcgtacgtg atgaagtgct ggtagaaatc gaaactnaca aagtggtact   1800
ggaagtaccg gcatcagcag acggcattct ggatgcggtt ctggaagatg aaggtacaac   1860
ggtaacgtct cgt                                                      1873

<210> 698
<211> 745
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (51)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (724)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (737)
<223> n equals a,t,g, or c

<400> 698
aattcggcac gagcaatgcc atgctgctga tggagtttgt ggagggcacc nagcacgacg     60
tggacctggt gttgtttggt gggcggttgc tggctgcctt tgtctccgac aatggcccta    120
cgaggctgcc tggcttcact gagacggcgg cctgcatgcc caccgggctg gcaccagagc    180
aggaggcaca gatggttcag gcagccttcc gctgttgcct gggctgcggg ttgctcgatg    240
gagtcttcaa cgtggagctc aarctgaccg gggctgggcc tcggcttatc gagatcaacc    300
cccgcatggg tggcttctac ctgcgtgatt ggatcctgga gctctatggt gttgacctgc    360
tgctggctgc tgttatggtg gcctgtggct tgcgtcctgc cctgcccacc cgcccacgtg    420
ctcgtggcca tctggtgggc gtcatgtgcc ttgtgtccca gcacctgcag gccctgagtt    480
ccaccgccag ccgtgagacc ctgcaggccc tgcacgaccg tggactgcta cgcctcaatc    540
tgctggagga ggccctggtg cctggcgagt atgaggagcc ctactgcagt gtggcctgtg    600
ccggacccag ccccaccgag gcccgtytcc gcctgctggg cctctgccag ggyctgggca    660
tcgatgggcc cagctamcct gttgcccact tcctgtctaa ttcaaataac actggggtaa    720
gggnggggga agcagtntgg gtgga                                          745

<210> 699
<211> 468
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (453)
<223> n equals a,t,g, or c

<400> 699
tggaaatgaa tgagtttctg gtggctgctc taataaactg ctacaagctt agtggtttta     60
aataatacag atttattatt ttacggttct ggatgtcagg agtccaaaat gagtcttaaa    120
ggactaagat caaaatgtct acagggctgg ttcctgtgga agctccaggg cagaatctgt    180
tgcttgtttc tttcacttcc agaggctgcc agcattcctt ggcttctggc tgcgtcacta    240
tgatctctgt ttccatgatc acattacctt cccctctaat gtacttaaat ctccttcagt    300
ttccatcttt ttttttagac ggagtttcac tcttgctgcc crggctggga gtggcaatgg    360
cacgatctcg ggctcactgg actttctgcc tcccgggttc aagtgattct tctgcctcag    420
cctcctacat gggctgggga ttacggacat tgncccacca cccccaag                 468

<210> 700
<211> 726
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (553)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (624)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (636)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (692)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (712)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (716)
<223> n equals a,t,g, or c

<400> 700
ggcacaggag cgacccggga gaaggagggc camgatggcg gaagcggagg agtctccagg     60
agacccgggg acagcatcgc ccaggcccct gtttgcaggc ctttcagata tatccatctc    120
acaagacatc cccgtagaag gagaaatcac cattcctatg agatctcgca tccgggagtt    180
tgacagctcc acattaaatg aatctgttcg caataccatc atgcgtgatc taaaagctgt    240
tgggaaaaaa ttcatgcatg ttttgtaccc aaggaaaagt aatactcttt tgagagattg    300
ggatttgtgg ggccctttga tcctttgtgt gacactcgca ttaatgctgc aaagagactc    360
tgcagatagt gaaaaagatg gagggcccca atttgcagar gtgtttgtca ttgtctggtt    420
tggtgcagtt accatcaccc tcaactcaaa acttcttgga gggaacatat ctttttttca    480
garcctctgt gtgctgggtt actgkatact tcccttgaca gtagcaatgc tgatttgccg    540
gctggtactt ttnggctgat ccaggacctg taaacttcat ggrtcggctt ttgtggtgaa    600
tgggatggtt ggctggtcta tagntggctt cacagntttc cttgctggaa accaagcctt    660
caaaccgaaa accctactgg taatcctgtt tnctggttac tttggcatca antggngatt    720
cttaac                                                               726

<210> 701
<211> 1615
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1560)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1600)
<223> n equals a,t,g, or c

<400> 701
gatggaagtt tatttcyctc tcccataaca gtgcagtgat agtcagctgg tccaggccag     60
gcaaggggct ggtccatgat gtcatcaggc acccaggttc ctactgtctt gccatgtggc    120
cacagttagc aacaaaggag gctgtaaatt tagtttctac ttgggcagcc aaaactctga    180
ggaaggagat tctgctagta aaaaggagtg ggggaagaat ggccattggg agacaacaag    240
cagactcaac caggcctctt tgttggcttc ctttcctcct gctgcacatg agccttcgcc    300
gtgcatttgg agccatgaca gctgatagct ccagacctgc atcctcctag cttgggggct    360
ctgaatgaaa ggtttcttcc cttccagttc gaatttggaa actcccaaag ttctcaatgg    420
tttgttgtga gttccatgtc ctcttggatc agtcactgtg gccatgcatg tttggccaca    480
tgattaatcc agtctgggtc atgacctttt cttcatccaa aacaaggtga tgggaagaca    540
aaaacaatag ctactacaaa caataggagt ttataattat gtgctgatgt attcgaagat    600
gtgttgacag tcgtgagtgt gtatcctagg aaaggcgagc tggactctgt ctccatggtg    660
gctctcaccc cagggaccta ggaacagcct gtcaccacac aattactttt ataaccctgg    720
agatgaaaat ctccttgtcc tcaaaatact tccagaagaa caaccagatg ggaaggacct    780
tggttgggac tctttccagt tcacttgggg cagagggaat ttaatggctc acgtagctga    840
aaaggatggg ctagattggg cttcaggctg catcccagga ctccaaacag ggatctgtct    900
ctttggctct cagctctgct ttcatttgag ttggctttat tcttgggctt cacagtgtgg    960
ccccacagca ccagttattg ataaaaagag ctcccctttg ctgacagaac tgctggattt   1020
ggttctcatt ggtccagacg aggaaggtat ccagcctcaa gtcatcattg tggccaggaa   1080
gatggaatac accaaatgga caggcctggc atgtacccac agagactgag agttggtgct   1140
ggtggttgtg gtggcagatg atattacctg aagaagggac gaatgggtgc tgggcaggac   1200
aaagcatcag ctgtccagtt caggcctctc ctctttccct ggtgtcttca ttttcctccg   1260
tctccctgct gtcccttacc ctctgcccaa tctctcatta ctcctggtct tgggagttgc   1320
cttctgagga tactccactg ggggtacctg agcctggatt agagggcagg gggaggatat   1380
tgcctagcca aagtgggtgt tcaataaaga accatttgga gatggtcttc tgtctggaac   1440
tgcttccttt ttgttttatt atttttcccc agatgagctg actgggccat ggaactgcat   1500
ccttatggtt cccatagcac cttaccgagg cgcccttatc aatagagttt agttatgtan   1560
ctgtgtcttg tctgaaccct actaactgtg agctcctgan gagtcaggcc tgagc        1615

<210> 702
<211> 947
<212> DNA
<213> Homo sapiens

<400> 702
ggcgtgacgg cgctcagcca tcccctgctc tacgtgaagc tgctcatcca ggtgggtcat     60
gagccgatgc cccccaccct tgggaccaat gtgctgggga ggaaggtcct ctatctgccg    120
agcttcttca cctacgccaa gtacatcgtg caagtggatg gtaagatagg gctgttccga    180
ggcctgagtc cccggctgat gtccaacgcc ctctctactg tgactcgggg tagcatgaag    240
aaggttttcc ctccagatga gattgagcag gtttccaaca aggatgwtat gaagacttcc    300
ctgaagaaag ttgtgaagga gacctcctac gagatgatga tgcagtgtgt gtcccgcatg    360
ttggcccacc ccctgcatgt catctcaatg cgctgcatgg tccagtttgt gggacgggag    420
gccaagtaca gtggtgtgct gagctccatt gggaagattt tcaaagagga agggctgctg    480
ggattcttcg ttggattaat ccctcacctc ctgggcgatg tggttttctt gtggggctgt    540
aacctgctgg cccacttcat caatgcctac ctggtggatg acagcttcag ccaggccctg    600
gccatccgga gctataccaa gttcgtgatg gggattgcag tgagcatgct gacctacccc    660
ttcctgctag ttggcgacct catggctgtg aacaactgcg ggctgcaagc tgggctcccc    720
ccttactccc cagtgttcaa atcctggatt cactgctgga agtacctgag tgtgcagggc    780
cagctcttcc gaggctccag cctgcttttc cgccgggtgt catcaggatc atgctttgcc    840
ctggagtaac ctgaatcatc taaaaaacac ggtctcaacc tggccacgtg ggtkagcctg    900
amcacttggg acactgcaar agatccaccc acaacaacag atttctc                  947

<210> 703
<211> 842
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (147)
<223> n equals a,t,g, or c

<400> 703
gagcagcccg caccggacaa cttgcgagcc atggggctgg cgggatgcgt ccggacgaag     60
gacacacagg cactgctgtc tgcaacacaa gcaatggacc tgcggangcg agactaccac    120
atggaacggc cgctgctgaa ccaggancat ttggaagaac tggggcgctg gggctcaaca    180
cctaagacca ccaatggcgg gaactggttc aatgctcccg tgctcgggcc tatgcccttc    240
tgctccaaca cytcccggtt ttggtctggt tacccggtat cctgtgcgtk actggctcct    300
gggtgamctg ttatccggcc tgagtgtggc catcatgcag cttccgcagg gcttggscta    360
cgccctcctg gctggattgc cccccgtgtt tggsctctat agctccttct accctgtctt    420
catctacttc ctgtttggca cttcccgaca gccctgtttc ggtcaccaga ctctgaacat    480
gctacatcct gcccaagact gcacctctgg aggtgcaggg cacccttgag aagcccctca    540
cccctaggcc gcctccaggt gctacccagg agtcccctcc atgtacacac acacaactca    600
gggaaggagg tcctgggact ccaagttcag cgctccaggt ctgggacagg gcctgcatgc    660
agtcaggctg gcagtggcgc ggtacaggga gggaactggt gcatatttta gcctcaggaa    720
taaagctaaa taaataaata aataaataaa taaataaata gtatgattct tctatgaaat    780
caggtgaatt ttataatacg aaactcacca tgaaaatatg actttcaaat ttcaaaaatc    840
ca                                                                   842

<210> 704
<211> 693
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (213)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (674)
<223> n equals a,t,g, or c

<400> 704
cccacgcgtc cgcagagatt taatgagcgt gggcctggac cttccccaga tgctgccagg     60
cagcccctcc ccaagcctca aagaagcatt tgctgaggat ggagaggcag gggagggagg    120
cgggaggccg tcactggagt ggcgtctgca gcagctgctg ccccagcacc cgctcagcct    180
gtcctggctg ctcacctccc cgcaggcacc ggngcctttc ctgccctctg tggtcatctg    240
ccacctgctg gatcaagtgc tttctctttt acactcccct gtccccaccc cagtgcactc    300
ttctggccca ggcggcaagc aagctgtgaa cagctggcct gagctgtcgc tgtggcttgt    360
ggctcatgcg ccattcctgg ttgtctgttg aatctttctg gctgctggar ttggagatag    420
gatgttttgc ttcccactgc aggagagctg ccccctttca cggggttggg gaagggtccc    480
cctggcctcc agcaggagca cagctcagca gggtccctgc tgcccamccc tctgagcctt    540
ttctccccar ggtatggctc ctgctgagtt tcttktccag carggccttg amaggaatcc    600
agggagtarc tcctggccag aaccagcctc tgcggggctt gtgctctgsa aaramtctgc    660
tgctggggaw tcangtctag aagggcaaag tat                                 693

<210> 705
<211> 970
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (781)
<223> n equals a,t,g, or c

<400> 705
tttttttttt tttttttttt tttttttcca ttcaagacca atttactctc aaattttgcc     60
aacacagaaa tattatcctt aaagaaatgt gcatttaaat cttttaattc acttcatcct    120
gtattttaaa ataaatgttt tccatataga ttttcccctt gggggggaaa agaattcagg    180
gtcttaggtt ccaggcagtt caaaaacagc cacgcggttc ttttttctcc accagaatac    240
cacaatagca gaacttaaga atcgggatat gaaaagggag gcgtggtcct ggcagtggcc    300
cctggccggc aggaatacac agcaacaccc aggcaggggc agcggctgcc cccatgccag    360
cctgcccatc cctgtaatga cagcagggca ggagatgcag ctgtggccct gggggcaggt    420
gggctctgag gctgcaaaca ccctgagtgc cagtggtccc agagggggtg aggcctctat    480
ctgtaccttt attccagcca gcctcctggc acagggctgg gcccacatcc tggcctctgc    540
atctggatca gggctggtgc tggtcagcct ggtcactctg gccagtgctc acactggaag    600
tccatgcaca ggcgaagtca cctccttccc gtgttaaata acaagaatgc caacacccca    660
cgcacgtgtc atctccagtg agcagacgtc caggcttccc gaagcttcct ggctggaaac    720
cgcgcagggc cggcagcgcc ctctccacca agggacacac cagcggcgcc tcctccgcgg    780
nccgggcccc catcccgcgg ctcgcgcggc caggacgccc caggtcggag cctgccccca    840
caccgcaccc ggaggccagc agcccagtcc cctaggccgc gcagcgccag cgagagcgag    900
gctgcagggc gaggcccggt gaggcgctcg agaactggcc gggaggagaa gtcaggcggc    960
ccacccgcca                                                           970

<210> 706
<211> 1568
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (27)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (47)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1548)
<223> n equals a,t,g, or c

<400> 706
cagaaattcg gncanaagnc acggggnaag ctggtgtgcg ccggatnaaa gatggcaacc     60
gccgatgaga ttgtgaaact ccatgctcga ccacatgaca aacaccacca acgcgtccca    120
tgtgcctgtg cagcccggct cctcagttgt gatgatggtc aacaacctgg gtggcctgtc    180
attcctggaa ctgggcatca tagccgacgc taccgtccgc tccctggagg gccgcggggt    240
gaagattgcc cgtgccctgg tgggcacctt catgtcagca ctggagatgc ctggcatttc    300
tctcaccctc ctgctggtgg atgagcctct cctgaaactg atagatgctg aaaccactgc    360
agcagcctgg sctaacgtgg ctgcagtctc catactgggc ggaacggagc cgggtagccc    420
ctgccgagcc ccaggaggcc cctgattcca ctgctgcagg aggctcagcc tcgaagcgga    480
tggcgctggt gctggaacgg gtgtgcagca ctctcctggg cctggaggaa cacctgaatg    540
ccctggaccg ggctgctggt gacggcgact gtggcaccac ccacagccgt gcggccagag    600
caatccagga gtggctgaag gagggcccac cccctgccag ccctgcccag ctgctctcca    660
agttgtctgt tctgctcctg gagaagatgg gaggctcatc tggggcgctc tatggcctgt    720
tcctgactgc ggctgcacag cccctgaagg ccaagaccag cctcccagcc tggtctgctg    780
ccatggatgc cggcctggaa gccatgcaga agtatggcaa ggctgctcca ggggacagga    840
ctatgctgga ttctctgtgg gcagcggggc aggagctcca agcctggaag agcccaggag    900
ctgatctgtt acaagtcctg accaaagcag tcaagagtgc cgaagctgca gccgaggcca    960
ccaagaatat ggaagctgga gccggaagag ccagttatat cagctcagca cggctggagc   1020
agccagaccc cggggcggtg gcagctgctg ccatcctccg ggccatcttg gaggtcttgc   1080
agagctaggg tgtgtgactg cctcccttgg cctcagctcc tctcactgct gtgctgaggt   1140
ggcctttgtc acttccttct gccttccaac cctcaccttc ccccggcctg gccccattgg   1200
cccaccctct aagttgagca ggaaatcctc caccaagctt ccagaactac agacagcacc   1260
cagagtgagc tggagtgggt ccccatgcct ctccagcatg ccctttccct ttgcaggagg   1320
gtggagtccc tgggtcatgc cctcccctgc cagctctggg cttcagagat aaggcatttt   1380
ccttgtgcag cctttacctg gcaatcctaa tttggtttta agactccctg tgaaatgctt   1440
tccgcacctt aaccccagtg agcgtgaaaa agaaagttaa taaactataa tacatggaag   1500
caaaaaaaaa aaaaaaaaaa actcgagggg gggcccggta cccaattngc cctatagtgg   1560
gtcttcga                                                            1568

<210> 707
<211> 1553
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (948)
<223> n equals a,t,g, or c

<400> 707
tttttttttt tttttttttt ttcaggcacc tccaaacata ttttctttat ttcctccaga     60
gaacaggctt tagtactgag gtccttgtaa acatttaaca aaactggttt aagaacaaac    120
taaaagcatc tatatccttg ccctgtgttg ctggggtgag tttatacaag gagaagttgg    180
aacaaatgca gtgggcacaa tgaccttctt actcagttca aagtaggtct tgggatgaga    240
gttccacacg gccagtacag ctgactttct gtgatttcca aggggtgccc aagacattaa    300
acgccatggt ccttgggaag gactgatgat gtttctgctc attgttgatc agggtcaaac    360
cttttcacta accgggactg ctctttccaa gaagtcagag gtcagaaagc tggtagcgtc    420
gtacaagacc gtctcgacag catgtgtaga tctgcttctc ccatgtggct accttgtaca    480
cagggtcaca gtcagcccca gtgagctcag tgacatagtc taagtcttgc tggacaataa    540
aacagcttcc atcaccttgg ctagcaatga atccatctct gacacttagc agggatagaa    600
ctggtgctcc tgatctgtgg atgacttgta ccggagccct tggactcctc acatccagct    660
gataaatgtt tccatcttga gtcccagcca atagcaagaa gccagagaga aaagtacagc    720
agttgaaagc gtctgagcca ataaagagga acaccagctg cctgctctgt agtcccaagc    780
actgaagttt cttatcttcc cgggccaaga gcagcatttt ggcctctgtt ccaacctccc    840
gttcactggg catctgctca ggggagccaa ggtttatgga gttgtcagca gcacccaccg    900
ccactccatt gatagaagaa ccacaatctg caaggactcc caagcagnct gagcgcccac    960
aatcccaaag tcgtgctgtc ccatctcgag aagcagacac cacattcctc ccccgatcaa   1020
cgatggctgt atccaggata cctcctttkt gacctttgaa ggtcaccacg cagctagcat   1080
cttcagctga ccatatcttc agctgggcat ccattccccc actcaggacc acaaggcctg   1140
atgggaaaaa cctgcaacaa ttcacatcaa acacatgtcc ttccaatact ctcctgagtt   1200
ctccattgga agcctgccag attttcatgg tcccgtcagt actagaagac acaccaagac   1260
ctcctctgct ggaaatgtcc aggcatgtta tactctttgt atgaattctg gaaaaagtag   1320
tatatggtgc caaaaactta gaagatgcat tttcctttgg acatgaaata tgaatgcttt   1380
tcttgtttat ttcattcaca gtaaatcctt ctgaagctgt aacctctggg atgccatcta   1440
ggccaattcc ttgacaagtc aggctgccat acaaagatgg tttccctggg ggatgacagc   1500
tcagccaggc ctccccttca tccttcctga gttgcgccca gtcgctctga atc          1553

<210> 708
<211> 2150
<212> DNA
<213> Homo sapiens

<400> 708
actacggctg cgagaagacg acagaagggg ggcggcgacg gaggaggagg atggaggcgg     60
tggtgttcgt cttctctctc ctcgattgtt gcgcgctcat cttcctctcg gtctacttca    120
taattacatt gtctgattta gaatgtgatt acattaatgc tagatcatgt tgctcaaaat    180
taaacaagtg ggtaattcca gaattgattg gccataccat tgtcactgta ttactgctca    240
tgtcattgca ctggttcatc ttccttctca acttacctgt tgccacttgg aatatatatc    300
gatacattat ggtgccgagt ggtaacatgg gagtgtttga tccaacagaa atacacaatc    360
gagggcagct gaagtcacac atgaaagaag ccatgatcaa gcttggtttc cacttgctct    420
gcttcttcat gtatctttat agtatgatct tagctttgat aaatgactga agctggagaa    480
gccgtggttg aagtcagcct acactacagt gcacagttga ggagccagag acttcttaaa    540
tcatccttag aaccgtgacc atagcagtat atattttcct cttggaacaa aaaactattt    600
ttgctgtatt tttaccatat aaagtattta aaaaacatga attgagtttc tgtagatttc    660
tagttctcaa ctttagcctg aacgccaaca cttgaaggtg tttttcatcc tctgtatgtt    720
gaaggtggtt atttgtatgt aggaacagga ctgccatccc agctttgcat gccaaagaaa    780
taaagaacac actttaaagg gcaaactgaa gagatgagcg agcaaaggtg cccttcaggt    840
ctactgaaaa gttagagtac aaaacaacac tgttgatctg gacaaaagaa gaaaaattac    900
cctttttgct tgtgttgtga caacttcatt taatatggtt taaagattta tgagactgtc    960
agctaaaagt cttttcacaa gaatgtcaac agagaatggc atctcaaaat atatatattt   1020
ctttkcacaa tttgtgaaac cttataagcc attttcccca ggtacaatgt agttcctgct   1080
gatagaaagg aaatattttg tcaagagctt tcatttaaaa gctactacct ccacaatcac   1140
ccccaaaccc agaaaatccc cactggctct tgccagtctg gttttcgtat tgcagttatt   1200
ccaattgtat ttgatctccc tgataacgta ttttcatggg tttgggtaga agatgctaat   1260
cagattagaa gcaggaatag ttatttgctg tctgtgaaat tgagcctttt ggtgcgccac   1320
gtggtgccag atcaacactt ctatccctct gcactgacca cgttgtgaac tgggagacca   1380
aatgcaagcc atttcatgga catagcaata tacaaccaaa ctctgttcct tggagttata   1440
ttgtaaactc ttgcaggtgg gagagcagtt cacctcctta gctctgtttg ccagctctta   1500
cagggtaaaa taaacctggc aatttatcct cagtcctagt ttgtggttta atgttgctat   1560
cttaagcact ggcatttggg caaaacatga ctgtgttctg tgggagaatc caaaggcatt   1620
attcactcta gttgagatag aattgggtgg ctaaacaggg tgtgtggtac ccaaaagatt   1680
aaatgttaca tgtcctttta gtccttgacc aggtctagcc ttggcagaag caagggagcc   1740
actaagccaa actccctgtg cagacagacc atgtttcaag gctggaagta gtgccctggc   1800
aacacacaaa aggaacggtg aaatggtagg caaagtgaac ttggctctgc tggcctcttt   1860
ggggtcacag aaattgctcc ttgtggtaat cttatattct gtcaggcaca gggccaagaa   1920
gctgtgtaac agacattact ttgcttgcat ctctttttca taccttttcc ctctgaggca   1980
gcttttgctt agaaaacagt cccttcactc tgcctttcct cctaacttcc tgtgcctctt   2040
catgttctgc tcaagctttt taaagcaacg aagctgttgg agaacttaaa tccttgcaac   2100
tgagagataa gctacttaaa ggcggtagag atcttttttt tttttttttt              2150

<210> 709
<211> 1872
<212> DNA
<213> Homo sapiens

<400> 709
ggctgagcga gccgctgagc gcggcgcagc tgcggcgact ggaggagcac cgctacagcg     60
cggcgggcgt ctcgctgctc gagccgccgc tgcagctcta ctggacctgg ctgctccagt    120
ggatcccgct ctggatggcc cccaactcca tcaccctgct ggggctcgcc gtcaacgtgg    180
tcaccacgct cgtgctcatc tcctactgtc ccacggccac cgaagaggca ccatactgga    240
catacctttt atgtgcactg ggacttttta tttaccagtc actggatgct attgatggga    300
aacaagccag aagaacaaac tcttgttccc ctttagggga gctctttgac catggctgtg    360
actctctttc cacagtattt atggcagtgg gagcttcaat tgccgctcgc ttaggaactt    420
atcctgactg gttttttttc tgctctttta ttgggatgtt tgtgttttat tgcgctcatt    480
ggcagactta tgtttcaggc atgttgagat ttggaaaagt ggatgtaact gaaattcaga    540
tagctttagt gattgtcttt gtgttgtctg catttggagg agcaacaatg tgggactata    600
cgattcctat tctagaaata aaattgaaga tccttccagt tcttggattt ctaggtggag    660
taatattttc ctgttcaaat tatttccatg ttatcctcca tggtggtgtt ggcaagaatg    720
gatccactat agcaggcacc agtgtcttgt cacctggact ccacatagga ctaattatta    780
tactggcaat aatgatctat aaaaagtcag caactgatgt gtttgaaaag catccttgtc    840
tttatatcct aatgtttgga tgtgtctttg ctaaagtctc acaaaaatta gtggtagctc    900
acatgaccaa aagtgaacta tatcttcaag acactgtctt tttggggcca ggtcttttgt    960
ttttagacca gtactttaat aactttatag acgaatatgt tgttctatgg atggcaatgg   1020
tgatttcttc atttgatatg gtgatatact ttagtgcttt gtgcctgcaa atttcaagac   1080
accttcatct aaatatattc aagactgcat gtcatcaagc acctgaacag gttcaagttc   1140
tttcttcaaa gagtcatcag aataacatgg attgaagaga cttccgaaca cttgctatct   1200
cttgctgctg ctgtttcatg gaaggagata ttaaacattt gtttaatttt tatttaagtg   1260
ttatacctat ttcagcaaat aaaatatttc attgcttawa ttaatcctta ttttttcaat   1320
ttcaatatga tcacttacag tttccatcat aatttttttt tgcaacatag ccatttcttt   1380
tttaaattca ttttgtgcac cagtaagtag attatcatga ttcttctcca actcttccat   1440
actctaaaaa cacaaaagac aagttaagtt acaaaggacc acttttcatc tcaggttcta   1500
aacttgtaca attaattttc aaaagtagta atttttgaat attcaaatgc tcatctattt   1560
gaaataaaaa tattctaagt aatacatgaa taccaaaata cctactaaaa aagaaaaaat   1620
ataagacatg aataaaatgt tataggaagt acaatgtagt atactttgcc caaaatgggt   1680
ttcctgaact gttaaggtca agataaaaaa gactggaagt cccacatcag taaaaaccat   1740
ttctattaag ctttccaaat atcaagcaat aatctactta tgactaatag tgtgccatga   1800
attcactaga gggaataaaa taatctatag tacaacctct ttcacattat gaaaaataaa   1860
aattatgtct ta                                                       1872

<210> 710
<211> 925
<212> DNA
<213> Homo sapiens

<400> 710
ggggaaatga tgagaatccg atgttccttt tgcacagtaa ggcagttact gtgtttgcca     60
gtgttattgg acatgctgag taagacatgg ggattttctc ccacagccag ttctttgacc    120
ttatgttgta ttctcatggt caaatagaaa ttgacgatca ggtggaagga ctccaatatc    180
tagcttctcg atatgatttc attgacttar atcgtgtggg catccacggc tggtcctatg    240
gaggatacct ctccctgatg gcattaatgc agaggtcaga tatcttcagg gttgctattg    300
ctggggcccc agtcactctg tggatcttct atgatacagg atacacggaa cgttatatgg    360
gtcaccctga ccagaatgaa cagggctatt acttaggatc tgtggccatg caagcagaaa    420
agttcccctc tgaaccaaat cgtttactgc tcttacatgg tttcctggat gagaatgtcc    480
attttgcaca taccagtata ttactgagtt ttttagtgag ggctggaaag ccatatgatt    540
tacagatcta tcctcaggag agacacagca taagagttcc tgaatcggga gaacattatg    600
aactgcatct tttgcactac cttcaagaaa accttggatc acgtattgct gctctaaaag    660
tgatataatt ttgacctgtg tagaactctc tggtatacac tggctattta accaaatgag    720
gaggtttaat caacagaaaa cacagaattg atcatcacat tttgatacct gccatgtaac    780
atctactcct gaaaataaat gtggtgccat gcaggggtct acggtttgtg gtagtaatct    840
aataccttaa ccccacatgc tcaaaatcaa atgatacata ttcctgagag acccagcaat    900
accataagaa ttactaaaaa aaaaa                                          925

<210> 711
<211> 1261
<212> DNA
<213> Homo sapiens

<400> 711
gcccacgcgt ccgcccacgc gtccggcggt gcggagtatg gggcgctgat ggccatggag     60
ggctactggc gcttcctggc gctgctgggg tcggcactgc tcgtcggctt cctgtcggtg    120
atsttcgccc tcgtctgggt cctccactac cgagaggggc ttggctggga tgggagcgca    180
ctagagttta actggcaccc agtgctcatg gtcaccggct tcgtcttcat ccagggcatc    240
gccatcatcg tctacagact gccgtggacc tggaaatgca gcaagctcct gatgaaatcc    300
atccatgcag ggttaaatgc agttgctgcc attcttgcaa ttatctctgt ggtggccgtg    360
tttgagaacc acaatgttaa caatatagcc aatatgtaca gtctgcacag ctgggttgga    420
ctgatagctg tcatatgcta tttgttacag cttctttcag gtttttcagt ctttctgctt    480
ccatgggctc cgctttctct ccgagcattt ctcatgccca tacatgttta ttctggaatt    540
gtcatctttg gaacagtgat tgcaacagca cttatgggat tgacagagaa actgattttt    600
tccctgagag atcctgcata cagtacattc ccgccagaag gtgttttcgt aaatacgctt    660
ggccttctga tcctggtgtt cggggccctc attttttgga tagtcaccag accgcaatgg    720
aaacgtccta aggagccaaa ttctaccatt cttcatccaa atggaggcac tgaacaggga    780
gcaagaggtt ccatgccagc ctactctggc aacaacatgg acaaatcaga ttcagagtta    840
aacartgaag tagcagcaag gaaaagaaac ttagctctgg atgaggctgg gcagagatct    900
accatgtaaa atgttgtaga gatagagcca tataacgtca cgtttcaaaa ctagctctac    960
agttttgctt ctcctattag ccatatgata attgggctat gtagtatcaa tatttacttt   1020
aatcacaaag gatggtttct tgaaataatt tgtattgatt gaggcctatg aactgacctg   1080
aattggaaag gatgtgatta atataaataa tagcagatat aaattgtggt tatgttacct   1140
ttatcttgtt gaggaccaca acattagcac ggtgccttgt gcagaataga tactcaatat   1200
gtgaatatgt gtctactagt agttaattgg ataaactggc agcatccctg aaaaaaaaaa   1260
a                                                                   1261

<210> 712
<211> 1357
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1334)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1344)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1349)
<223> n equals a,t,g, or c

<400> 712
aaaatattca agaagtgtaa aaaggggatc ctggtgaaca tggacgacaa cattgtgaag     60
cattactcca atgaggacac cttccagctg cagattgaag aagccggggg gtcttacaag    120
ctcaccctga crgagatcta aaggcctgcg ggcacagctc cccaggagtt cagtgcaggt    180
gtttctagat cttacggttt ggcaactgca ggtaacccca gtcagccatg tcgccagcac    240
aggtctatgt cgagggaatg ggttccttgc argttggagg cggggytgca tctggcttgg    300
tggtagcatt taatctattg cattggtgtt tttcagatga aagagaaatc catataccat    360
tatgtttgaa tttcctgata tatacaggat ttaaagtgaa aactttattc caagagttaa    420
cagagtctct gggaagcttt aggacatctg ctacgttatt tatcaaaata ttgggatctc    480
tgccttgtgc ctacagtgtc gtgggcctgc tcgctagcag aagtcagaaa aggcgatagg    540
cttggcttta aggatttcgt gcccttgcct gaattcagta caactccact gcctcacgtt    600
agcgggacgc acctgaagag tacgggggga gccctctctc ccttaccctc tcactctcca    660
ccagatgttt actaaacagg gcatgttact gaaatcttcc tttgcgactt tctcggacat    720
atcaactgcc tttctcatga agaattttaa tgggttacag tatgaaatca gttaagataa    780
agctgcattg tatataagtg caatatattt ttgaaggtct gtaaatgtgt acatacatgt    840
cttatataaa tatataatat ataaatatgg tgtctgtgta catatagtga aratatgcag    900
taagagctac cttaaagact ttccctagac aaaggttaag ttattttttg atcgtgtata    960
ccaagcagat agaatactgt gcttagtgga acccgctaaa aacctttttc tctgtttttc   1020
caaacacagg cattctgtak catagcaaaa ccttctcaaa tgacagagat tctgtttgct   1080
gttgagaatg ttgttatttg gatttctgca ctgtttaaca aatgaagtaa aagaaaaaca   1140
ctactgcaat cacgtctttt gttatgctag tatcagtcag atgcacttag agtgaagaaa   1200
cactgtaatt acagcacaca gattgcaagt attgcgtacc aagtgataca actcgaaatg   1260
cagttctcat cttcctgttt tgaggaatga ttattttttt cacggctccg ggccttcggt   1320
gcttttgatt atcntgtatg gttnaacant tctaggg                            1357

<210> 713
<211> 600
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (466)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (513)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (569)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (585)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (596)
<223> n equals a,t,g, or c

<400> 713
gcggacgcgt gggcgggacc gcagactctt agggcccctc tctttggcca tctgcctcta     60
ggtcccatcc tggggcctga agcgcttgtt ctctgcgctg ggaaaagggg aacgatggag    120
cgatccagca cccaaactta ccctgtccag gtctgagagt cactggagct accagaagca    180
tcatggggcc ctggggagag ccagagctcc tggtgtggcg ccccgaggcg gtagcttcag    240
agcctccagt gcctgtgggg ctggaggtga agttgggggc cctggtgctg ctgctggtgc    300
tcaccctcct ctgcarcctg gtgcccatct gtgtgctgcg ccggccarga gctaaccatg    360
aargctcarc ttcccgccar aaarccctga rcctartaag ctgtttcgcg gggggcgtct    420
ttttggccac ttgtctcctg gacctgctgc ctgactacct ggctgncata gatgaggccc    480
tggcagcctt gacgtgacgc tcagttccac tgnaagaagt catcctggca tggcttcttc    540
tggcctggtg atggacagaa cacaatggnt tacaaggaca gtcanggccg cacctntgga    600

<210> 714
<211> 1022
<212> DNA
<213> Homo sapiens

<400> 714
tttttttttt ttatggtaag ccaatgtttg tttttatttt attggccatt ttgtcttcct     60
acttctctag gtatagtgaa cataggtgtg aataatgtcc aggagttgat tattgcagca    120
gacatgctac agttgactga agttgttcat ctttgctgtg aatttctgaa aggacaaatt    180
gatccactga actgcattgg aatttttcag ttctctgagc aaattgcctg ccatgatctc    240
ttggaattct cagaaaacta cattcatgtc catttcttgg aggttcatag tggagaagag    300
ttcctggcac ttacgaaaga tcagctgatc aaaattttgc gaagtgaaga gcttagcatt    360
gaggatgaat accaggtctt cttagctgca atgcaatgga ttctgaaaga tttgggaaaa    420
agaagaaaac atgtggtgga agtgctagac ccaattcgat tccctttatt acctcctcag    480
agacttttaa agtatataga aggagtatcc gattttaatc ttcgtgttgc attgcaaaca    540
cttctgaaag agtactgtga agtatgcara tctcccaaag agaacaagtt ttgtagtttt    600
ctgcagacat ctaaggttcg acctcggaag aaagcaagaa agtacctgta tgcagtaggt    660
ggatatactc ggttgcaggg gggtcgctgg agtgatagca gagccctcag ctgtgtagaa    720
cgttttgaca cctttagcca gtactggacc actgtgtctt cacttcatca ggctcgaagt    780
gggctgggag taacagttct gggagggatg gtctacgcta ttggaggtga aaaggattca    840
atgatttttg attgtactga atgctatgat ccagttacta aacagtggac aactgtagct    900
tcgatgaatc atccccgctg cggcttagga gtgtgtgtgt gttatggggc yatctatgct    960
ttgggtggat gggttggagc tgagataggg aacacattga acgatttgat cctgatgaaa   1020
at                                                                  1022

<210> 715
<211> 2447
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2315)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2333)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2400)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2438)
<223> n equals a,t,g, or c

<400> 715
gcagggctct cgctctgaaa gccgtccact gcggtcctgt cgagcagggt caggaggaca     60
cagtggcacc cgaagtggca gcggaaaagc cggtcggagc tttattgggc cccggtgccg    120
agagggccag gatggggagc aggcccagga tacacccact agtgcctcag gtgcccggcc    180
ctgtgactgc agccatggcc acaggcttag ctgttaacgg gaaaggtaca tctccgttca    240
tggatgcatt aacagccaat gggacaacca acatacagac atctgttaca ggagtgactg    300
ccagcaaaag gaaatttatt gacgacagaa gagaccagcc ttttgacaag cgattgcgtt    360
tcagcgtgag gcaaacagaa agtgcctaca gatacagaga tattgtggtc aggaagcagg    420
atggcttcac ccacatcttg ttatccacaa agtcctcaga gaataactca ctaaatccag    480
aggtaatgag agaagtccag agtgctctga gcacggccgc tgccgatgac agcaagctgg    540
tactgctcag cgccgttggc agcgtcttct gttgtggact tgactttatt tattttatac    600
gacgtctgac agatgacagg aaaagagaaa gcactaaaat ggcagaagct atcagaaact    660
tcgtgaatac tttcattcaa tttaagaagc ccattattgt agcagtcaat ggcccagcca    720
ttggtctagg agcatctata ttgcctcttt gcgatgtggt ttgggctaat gaaaaggctt    780
ggtttcaaac accctatacc accttcggac agagtcagat ggctgttcta ccgttatgtt    840
tcccaagata atgggaggag catctgcaaa cgagatgctg ctcagtggac ggaagctgac    900
agcgcaggag gcgtgtggca agggcctggt ctcccaggtg ttttggcccg ggacgttcac    960
tcaggaagtg atggttcgca ttaaggagct tgcctcgtgc aatccagttg tgcttgagga   1020
atccaaagcc ctcgtgcgct gcaacatgaa gatggagctg gagcaggcca acgagaggga   1080
gtgtgaggtg ctgaagaaaa tctggggctc ggcccagggg atggactcca tgttaaagta   1140
cttgcagagg aagatcgatg agttctgagt gtcgggctgc ccactggtga caccgggatc   1200
gggctgagca ggagaacatc accggctcca gttcccctga tccattctca cagcctgaaa   1260
caagctcacc cgtagcttac gcttggaagc aggactggga acatccacgc tatttattat   1320
cgaggagttt taaagtactg taactttaaa ataaataact acaaagcttc tttgtccaaa   1380
cgtcattatt ttatacttat atacacgcag gtgtaaaagt ataaaggtga gcactagact   1440
gctcttagaa gctctaattt ttgttttctt tggctagtac tgtataaaaa acagaattgt   1500
gttttattgg ttttggatga cagaaaagtc tggaataatg tttgttttcc tcatttcttc   1560
cttctagaac acagaatcta aaggggtrtt agccagcctc gcctccctgc cccacgtaga   1620
gacacagagt gatgtgaggc gttggctttt tctccaagaa ggtacagata cctcagattc   1680
gggaaactca aaatcaaaag acttagcttc taggataaat acttctgatg aaaaatccgc   1740
tgaggagcat accccaaacc agacatatgc ttaggattca tgctgagata tcaattggtt   1800
tccccttctt tttaaaatac gtccagttct tacccagtta acatgaagaa accactgtct   1860
ctagaagaaa gcttgttttg cagtattagt gaatcactga atagcttaag tatgactatc   1920
taagttataa gttagtcttt agtgggtttt aaatagtttt tctgaccctt ctgaaaaata   1980
actacataag tgcttcttgt tgctgggtga gaaatactac tttatagaca gttttggttt   2040
tctgtttgca gatatgattg atgtatttca ccaaaataaa atatttttat gtttataaag   2100
tgtaattttt aggttcactt agaatatatt ttatttaata agttaaaatt cttttggcac   2160
actattaaat gcaaaaactc ctttcaaaac aaaaaagaac taccttatat tcaacattta   2220
atgttcttgg cctctctttt atgtctatac aatatactga gttcagtatg ggtgtccaag   2280
agtgccctgt gtggggatag gacatgtgca ctccntcccg gggttggggt acntgatttc   2340
ccggacttcc aggtggcccc ttttttgggt aggggcttct tgaggccttg ccattcatan   2400
ttgaatggta tgggaggggg cctaaatcca aattcccnaa tttttgg                 2447

<210> 716
<211> 865
<212> DNA
<213> Homo sapiens

<400> 716
gttcacacgg gttgcttcgg aggaatccgc cgtgcaaatc tgtccgcccc cttggccact     60
gatcccccga agagcttctg tcgccgctct aggaatacag acattgaagt ttgggacaag    120
atatttatct aacttctgtg tcaaaattag cgacctgcta tggcaatgaa gaaagaaact    180
gaatttgtca ttttcacctg aagaaaaatg atagacaaaa atcaaacctg tggtgtagga    240
caggattctg tgccctatat gatttgtctg attcacatac tcgaagaatg gtttggtgtg    300
gagcagttgg aggactattt gaattttgca aactatctct tgtgggtttt tacaccacta    360
atacttttaa tacttcctta ctttactatc tttcttctct accttactat tattttctta    420
cacatttata agagaaagaa tgtattgaaa gaagctactc tcataattta tgggatggtg    480
caaggaaaac agtggcaact ctgtgggatg gacatgcagc cgtttggatg gtaagcaagg    540
atactttcac ctttgtgttg ccattcatgt gtgctgcatt ggaactgtgt taccattcca    600
ttttattgat tgagaagata ctgaaaatat aatagaagtg atatttacta ttccctgtta    660
cctgtttgca tgcattgtgc atatgtatgt gtctttctta aaatgagttt tcccatagac    720
gttggtttcc attaaacaaa gaaccacgca gcactgtaga ctataagttg aaataagaaa    780
atttatattt aaaacatcta aaagagtaag agactaaata aagctgtaga aaactgaaaa    840
aaaaaaaaaa aaaaaaaaaa aaaaa                                          865

<210> 717
<211> 672
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (572)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (623)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (633)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (636)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (653)
<223> n equals a,t,g, or c

<400> 717
gcctcgcgnt actntggggg gatggttcca tcatggcgtc aatgcagaaa cgactacaga     60
aagaactgtt ggctttgcaa aatgacccac ctcctggaat gaccttaaat gagaagagtg    120
ttcaaaattc aattacacag tggattgtag acatggaagg tgcaccaggt accttatatg    180
aaggggaaaa atttcaactt ctatttaaat ttagtagtcg atatcctttt gactctcctc    240
aggtcatgtt tactggtgaa aatattcctg ttcatcctca tgtttatagc aatggtcata    300
tctgtttatc cattctaaca gaagactggt ccccagcgct ctcagtccaa tcagtttgtc    360
ttagcattat tagcatgctt tccagctgca aggaaaagag acgaccaccg gataattctt    420
tttatgtgcg aacatgtaac aagaatccaa agaaaacaaa atggtggtat catgatgata    480
cttgktgatg ccactgktat catcctccta gcagaagata gtcctactga gaaaatgagc    540
actttgatca ttcagtcttt gaactttaac cntttgactg gaartgacct ataggcaatg    600
ragactactt ycctttactg canttttacy cgnggngcaw tctgggcgca tgntkgatcg    660
ytggtaatcc ag                                                        672

<210> 718
<211> 574
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (454)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (523)
<223> n equals a,t,g, or c

<400> 718
gtgggatgag ggtgaaactg ctattgccgg cggctcctgt tttaccgcgt cagcatgctg     60
gtgcatttat ttcgggtcgg gattcggggt ggcccattcc caggcaggct gctaccgccc    120
ctccgcttcc agacattctc agctgtcagg tactctgatg gctaccgcag ctcctccctc    180
ctccgggccg tggcccacct gcggtcccag ctctgggccc acctccctcg agccccccta    240
gctcccagat ggagcccctc tgcctggtgc tgggttgggg gagccctgct aggccccatg    300
gtactgagta agcatcccca cctctgcctt gtggccctgt gtgaggcaga agaggcccct    360
cctgccagct ccacaaccca tgtcgtgggg tctcgcttta actggaagct cttctggcag    420
tttctgcacc cccaactgct ggtcctgggg gtanccgtcg tgctggcctt gggtgcggca    480
ctcgtgaatg tacagatccc cctgtcctgg gcaaacttgg tanaagtcgt gggccaagta    540
cacaagggac cacgtaaggg agttcatgat tgaa                                574

<210> 719
<211> 818
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (726)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (760)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (781)
<223> n equals a,t,g, or c

<400> 719
ggcagtgtgt ggccatctaa cgtgccatcc agttcttcag gctgtcattc tgtcagagcc     60
tggagtcgag gctgcgaggg ccctggctgg ctgggtgttg cctgagagtt gcccagggga    120
ataagacttt taagactaga ttttgtgctc agtgcctcat tcctctgcga ctttgcccat    180
ggacatgtct tagaaactga agttgcttca gaacagccct gagaagggca ggggcaaggg    240
cctgacagaa gaggaagtgc tccttccaga gggctcagcc agagccccat gggtgtgctg    300
gtcagcagga gggcagtcgg agcctcaagc catccatgcc tctctctcct tacaggtact    360
ctgatggcta ccgcagctcc tccctcctcc gggccgtggc ccacctgcgg tcccagctct    420
gggcccacct ccctcgagcc cccctagctc ccagatggag cccctctgcc tggtgctggg    480
ttgggggarc cctgctaggc cccatggtac tgagtaagca tccccacctc tgccttgtgg    540
ccctgtgtga ggcagaarag gcccctcctg ccagctccac accccatgtc gtggggtctc    600
gctttaactg gaagctcttc tggcagtttc tgcaccccca cctgctggtc ctgggggtag    660
ccgtcgtgct ggccttgggt gcggcactcg tggaatgtta cagatccccc tggttcctgg    720
ggccanntgg taaaagttct gggccaatta cacaagggan cactaaggga ttttcatgga    780
nggattccca gaatttcagc aaccactggt ttatccct                            818

<210> 720
<211> 1059
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (978)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1058)
<223> n equals a,t,g, or c

<400> 720
ctggatgaca gagcaagact ccatctcaaa taataataat aaggctagta tgactaagga     60
gctaaatttt aattttgtta tasttcattt taatttagat agccatgtgt ggctaagggc    120
taccatattg agaagtgctg ctaaagagca agactgattt ttctctctcc ccgctgacag    180
gaggttatga gggagagggg attggggcct cttggggttt ttagatctga cgctggtctg    240
aaatctctac ctgagggtag gagggagagt ggggctctgg aggagtgtgt tattcacact    300
cagagagtct gtgattggaa ggtgcctgaa cacccacttg cacctctcct tttgttgtcg    360
tttgcagtct tgaggatact ggctaagcct ctgcctacgc atgagtcctg ttccttctcc    420
tctccaggtc ttccctcttt aaccaacatt tccctctctg ctgattcttc ctttctgcct    480
tcaaatgcaa gtccctgcta cctccaacca ggcaactttt caaatgaatg aactgaagca    540
atttctcccc tttgtcacac actccctctg ccacagaaga cttgctttct tactcatagt    600
gcccctttcc tgaccggttc aggsgctggt tcagagttca tcctttytaa cattcttgtc    660
actctgmccc tattaatgas gtcttkgtyg caacgtctst cctcstgtag cttctgtggc    720
ggccytcttg gctccatagm cctcctstgc cttctctgcc tsagstacty gtttcatact    780
cctsaactgt gagtgtcttc taaggcttgt ttcctgactt tttcctcact ctacatcatc    840
ctccttgaca gtacagctat gtttatgacc ttagctacca cctctccaca aatgagtcct    900
cgacctaaat ctcttattct gatccttcac cagtggaaag gatagaaact agagcatagc    960
ttccataaga ttatgggnca aatagtccag gcacggtggc tcacgcctgt aatcacagca   1020
ctttgggagg ccgaggtggg cagatcacgg ggtcaggng                          1059

<210> 721
<211> 2430
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<400> 721
tntttttcct ttttacaaaa acatgcatac atacacaggg tatggtgggt cctaggaaag     60
acacacacac acgcytcaca cacacacgct cacacacacg cctcactcac acacatgctc    120
acacacattt tccttcttga ccccaggcct ggacccccaa aagccttgaa gactttgcca    180
gagcagcctc ccctcctcca tgtctgtatc ttytctccca ccccttcccc ytcagtcagg    240
ctattcctat gtggggtggg aatcagagct atggtggggg aggccccaga aacagagaag    300
gctccccgag tgggcagtgg ccgaggggtc ccaggggtat sctgcgcttc tgggggagat    360
gaagggtttg gcaccattgg atcaggaagc acaggactcc cagagcaccc atctgctcca    420
ccagggcatc gccaggaggt tgatgtaggg gggcctctgg cgagggtacg gaccagatgg    480
agggctgcca gtctcggctg tcagggagct tcgtctcagt gcccggtggt agagggaagc    540
ttccagagtc gtctgaggaa gcaggtgaga gggactaccc ctgcactcag gaatatggga    600
cctcttggct ccccactccc ccctagcccc tagagcctag gaagggccag cctgtctgag    660
gccaagttca catttctgtg tggagcctgg ggctgtgtgc aaagtctggg gtttgcagag    720
ccaggaatag tggttaaggg tgagcccgac ggagccggag ccagtcctcc tctgtgcagt    780
cctgaggaat gggggccaca gccagggccc atactggagg ggagaatctg ttctcgagag    840
ccctgtgggg gtcgccgccc agcccgtctc ctctcagggt cctctccagt tcccattcta    900
gacccaggga ttttctcacg ctccctggga taactgtcaa agcaggcagg ctgttctctg    960
gttccaacta cttgcccaca ggatctctaa agacccagga atgggggcta ttgccagggg   1020
ttagaagaga accaggtccc aagggcatgg tgggcgggca gatggttcca gagccttaga   1080
gattcatagg ttcttcctcc tccaccagct gctccgaggg cctatcttca gccaggatgc   1140
ccacagagag ggacgccagt gcggtcactg cctccacttc ttctttgtca gcccctggca   1200
ctctaggcac ccaggagtct ggacaggagg ccaggcgctg catgcagccc cagtatttac   1260
tgtgcacccg gatcacggcc tccagagagc ggatggcatt gaggttgggt ttctgtttcc   1320
agccttcttc tgaaagggga tccaccctgt tacccagaag agcagccaca caggcctcag   1380
aggcgtcaca gatggctgtg aggtcatggc caccctccaa ggccagcacc actgcgcctc   1440
ctgccaggtt catcagttgc tgcgtcatgt atccaaaaca tttggcagaa acatggtagc   1500
cacccagtgg ggccgggtga ccctcagcag catcaaatcc agcagacacc aggactaggt   1560
ctggagagaa ctytcgggcg atgggcatca cgactatcct gaaagcagcc aggtactcag   1620
gatcccccat gggggggtcc agacctccag cccaggccac attgacattg aagccctcac   1680
cgctgccagc ccctacctca tccacagccc cactccccgg gaagaagttg ccgtcgtcat   1740
ggcgatgcag ggagatgtag agcacactgg ggtcttggta gaaggtttgc tgggtgccgt   1800
tgccatggtg cacgtcccag tctacaatga ggatcttgct ggccttgctc tgctgttgca   1860
gctgccggca ggcgatggcc actgagttga agaagcagaa gcccatggct gttgaatgat   1920
ctgcatggtg tcctgggggc cgcaccacag cgaaaccatt ctttagctca cgagaagcca   1980
ctttgaaggc gaggtcagtg acactgccag cggcccagcg ggctgcattg gaggaatgaa   2040
gctcattcca gatggtgtca gtgtccaccc caaccccacc acagggcagc atcacaaaca   2100
tccgctgtgc caggagccct gccagcttcc cgttgtccag tttgaggcgg ctgagcgggt   2160
tggtgccgta gaggagcacg tgccgctcag agtggaccga ctgcagctct tccagggagg   2220
ccttccggcc tcggagacac tcacactggc tccggagccc ccgctcctgc agccgggacc   2280
agatgctctg gatgcggccg gcgtgctccg ggtgcctgct gttgtcaccg caggagcact   2340
ggtgcttcag catgaccgag tcatagatca gccctgtggt gaagggcagg gtcctggcag   2400
gggtctctga gctggagagg actcgggccc                                    2430

<210> 722
<211> 1551
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1467)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1475)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1520)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1546)
<223> n equals a,t,g, or c

<400> 722
ggcacgaggg gagttkgcgg acggtccctg gctgggttct ggaggccctg ggaccgcgga     60
agaggcttca gacgctgcag cgatgcctcg cccacggcgg gtcagtcagc tcctggatct    120
atgcctttgg tgcttcatga agaatatttc cagatatctc acagacatta agcctttgcc    180
tcccaacata aaagacagac tgattaaaat aatgagtatg cagggacaga taacagattc    240
aaatataagt gagattttac atcctgaagt ccaaactcta gatctacgga gctgcgatat    300
atcagatgct gctctcctgc acctgtctaa ctgtagaaaa ctgaagaaat taaatttaaa    360
tgcttcaaaa gggaaccgag tttctgtaac ttcagaagga ataaaagctg tggcttcatc    420
ttgttcatac ctacacgaag cttctttgaa aagatgctgc aatctcactg acgaaggagt    480
cgttgctctt gcactcaatt gccagctgct aaagatcatc gatttaggtg gctgcttaag    540
tattactgat gtgtccttac atgcattagg aaaaaactgc ccatttttgc agtgtgtcga    600
cttttcagct actcaggtat ytgacagtgg tgtgattgca cttgttagtg gaccttgtgc    660
gaagaaatta gaggagattc atatgggaca ttgtgtaaat ctgactgatg gggctgtcga    720
agctgtcctt acttactgtc ctcaaatacg tatattactc ttccatggat gccccttgat    780
aacagatcat tcccgagaag tgttggagca attagtaggc ccaaacaaac taaagcaagt    840
gacatggact gtttattgat gcttttttga agatgatcaa tgctaggaaa gcttatcaaa    900
actactttcc caggaaacca tctatagaga tttgcattct acttaatgtt aacactattt    960
ttaattattt tattgtctta agttataact ctcagagaat tagctaagtc ttggtatata   1020
catggtttgt gctttactct taaacatctt taaagtgcta ttattctata tctgttggat   1080
gagtcattat ttttgaaatg ataatcctag catgaactct gatctrtggt gttggattct   1140
gtttcttaaa taactttaaa attaactgtt ttcccttgag atttccttct cctatgtagg   1200
tatttgagct attgttctaa gtttacctgt aagtataaac cttgggagaa tctaagtaaa   1260
catatttcta aaagcatagt taccttccta ttttctggct cttaccttct tggagtattt   1320
aaatgcccat ttgccaaaag cagacctgaa catcaagcct gttaattctt caaagaattt   1380
aggkgattkg tttccccgga aatggagtga cttattagcc attcagcggt attaggaata   1440
cagaggctct tgcccagcca catccantcc attgntttta aggggactcc tcccaggtac   1500
attttaaggc accggtagcn ttccctccct aggcaaattg catccnaaag g            1551

<210> 723
<211> 1396
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (496)
<223> n equals a,t,g, or c

<400> 723
aactagtgga tcccccgggt tgcaggaatt tggcacgagc cggaagctgc ctgnaagctg     60
gacagagccg gttcctggaa agagctggtt ccctggcagg ctggagggca ggagctgggg    120
ccacgctggt ctgggatagt tgggcaggga ggctgtctac ctggtctcca gaatggacgg    180
ccctgtggca gagcatgcca agcaggagcc ctttcacgtg gtcacacctc tgttggagag    240
ctgggcgctg tcccaggtgg cgggcatgcc tgtcttcctc aagtgtgaga atgtgcagcc    300
cagcggctcc ttcaagattc ggggcattgg gcatttctgc caggagatgg ccaagaaggg    360
atgcagacac ctggtgtgct cctcaggggg taatgcgggc atcgctgctg cctatgctgc    420
taggaagctg ggcattcctg ccaccatcgt gctccccgag agcacctccc tgcaggtggt    480
gcagaggctg cagggngagg gggccgaggt tcagctgact ggaaaggtct gggacgaggc    540
caatctgagg gcgcaagagt tggccaagag ggacggctgg gagaatgtcc ccccgtttga    600
ccacccccta atatggaaag gccacgccag cctggtgcag gagctgaaag cagtgctgag    660
gaccccacca ggtgccctgg tgctggcagt tgggggtggg ggtctcctgg ccggggtggt    720
ggctggcctg ctggaggtgg gctggcagca tgtacccatc attgccatgg agacccatgg    780
ggcacactgc ttcaatgcgg ccatcacagc cggcaagctg gtcacacttc cagacatcac    840
cagtgtggcc aagagcctgg gtgccaagac ggtggccgct cgggccctgg agtgcatgca    900
ggtgtgcaag attcactctg aagtggtgga ggacaccgag gctgtgagcg ctgtgcagca    960
gctcctggat gatgagcgta tgctggtgga gcctgcctgt ggggcagcct tagcagccat   1020
ctactcaggc ctcctgcgga ggctccaggc cgagggctgc ctgccccctt ccctgacttc   1080
agttgtggta atcgtgtgtg gaggcaacaa catcaacagc cgagagctgc aggctttgaa   1140
aacccacctg ggccaggtct gaggggtccc atcctggccc caaagacccc tgagaggccc   1200
atggacagtc ctgtgtctgg atgaggagga ctcagtgctg gcagatggca gtggaagctg   1260
ccctgtgcaa ctgtgctggc tgcctcctga aggaagccct cctggactgc ttcttttggc   1320
tctccgacaa ctccggccaa taaacacttt ctgaattgag aaaaaaaaaa aaaaaaactc   1380
gagactagct cgtgcc                                                   1396

<210> 724
<211> 540
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (294)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (524)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (532)
<223> n equals a,t,g, or c

<400> 724
gagccggcgg gcggggcggg taagatggcg gccccgcggc gagggagagg atcctccaca     60
gtgctctctt cagttcccct tcaaatgctg ttttatctca gcggaacgta ctacgccctg    120
tatttcctcg ccacgctcct gatgatcacg tataaaagtc aggtgttcag ctatcctcac    180
cgctacctgg tcctcgatct tgctctgctg tttctratgg ggattctaga agcagttcgg    240
ttatacctgg gcaccagggg caacctgaca gaggctgaga ggccgctggc cgcnagcctg    300
gccctcacgg ctggcaccgc ctcctctctg cccacttcct gctttggcag gccctagtgt    360
tgtgggcgga ctgggccctc agcgccacgy tcctggccct tyacggcctg gaaggccgtt    420
ccttgcaggt ggttgccatc gggggccttc accaggtagt tacgggacaa ccgggattac    480
cccacattgg ggggccttcc tcctgggcct gaccaattcc ccanttgtaa anttcccatt    540

<210> 725
<211> 620
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (552)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (620)
<223> n equals a,t,g, or c

<400> 725
attgccaaca tgwttctagg aattatcatt ttgaagaaaa gatacagtat attcaaatat     60
acctccattg ccctggtgtc tgtggggata tttatttgca cttttatgtc agcaaagcag    120
gtgacttccc agtccagctt gagtgagaat gatggattcc aggcatttgt gtggtggtta    180
ctaggtattg gggcattgac ttttgctctt ctgatgtcag caaggatggg gatattccaa    240
gagactctct acaaacgatt tgggaaacac tccaaggagg ctttgtttta taatcacgcc    300
cttccacttc cgggtttcgt cttcttggct tctgatattt atgaccatgc agttctattc    360
aataagtctg agttatatga aattcccgtc atcggagtga ccctgcccat catgtggttc    420
tacctcctca tgaacatcat cactcagtac gtgtgcatcc ggggtgtgtt tatcctcacc    480
acrggaatgc gcctccctca mcgtcacgct cgttcgtgac cttacgcaaa tttgtggagc    540
ctccatcttt tnccatcttg gtgactttcc agaacccctt tcaccctgtg gggcaatggg    600
ctggggcaac ttggtttgtn                                                620

<210> 726
<211> 359
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (322)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (357)
<223> n equals a,t,g, or c

<400> 726
gccatggctt cattacccca gctgatggcg gccccgacat cttcctgcac atctctgagt     60
gagtcagcgg caggtctggg tggcctggct ggggtgggcg cttccttggc cctgtggagg    120
tggggatggt gtgtgactct gatgggcgct gtgtgtgagg acgaatggct gggcctgtgt    180
gactctgcct gtggctggtg ctycwgctgt gctcctgtgt gtgtgttggg ttkgggttgt    240
gagactctac ggagctgtgt tgggggatgt gaagctgggg gcgacacggt acttgtgatt    300
gtccctgggt gtgtctttgt gnaatgggtg tgtaaagttt tgtgtgtcct gggcctngt     359

<210> 727
<211> 1407
<212> DNA
<213> Homo sapiens

<400> 727
gagtggagga ggaagaggcg gtagggggta cgggggctgg tcccagaaga tggcggaggc     60
gggggatttc tggtaggtcc tactttagga caagatgtgg taccgttgaa gcgtcagtct    120
ttgattcaca gacagttgag cttttcagct gggaagcctt tccatttttt tttttttaac    180
ggctttctga acctatgaaa ccatggcaga aggagagaca gagtcacctg ggcccaaaaa    240
gtgtggccca tatatttcat ctgtcactag ccagagtgtg aacttgatga ttcgaggart    300
agtgctattt tttattggag tatttcttgc attagtgtta aatttacttc agattcagag    360
aaatgtgacg ctctttccac ctgatgtgat tgcaagcatc ttttcttctg catggtgggt    420
acccccatgc tgtggcacgg cttcwgctgt gattgggtta ttatacccct gcattgacag    480
acatctagga gaaccacata aatttaaaag agagtggtcc agtgtaatgc ggtgtgtagc    540
agtctttgtt ggtataaatc atgccagtgc taaagtggat ttcgataaca acatacagtt    600
gtctctcaca ctggctgcac tatccattgg actgtggtgg acttttgata gatctagaag    660
tggttttggc cttggagtag gaattgcctt cttggcaact gtggtcactc aactgctagt    720
atataatggt gtttaccaat atacatctcc agatttcctc tatgttcgtt cttggttacc    780
atgtatattt tttgctggag gcataacaat gggaaacatt ggtcgacaac tggcaatgta    840
cgaatgtaaa gttatcgcag aaaaatctca tcaggaatga agaaggcaaa aaatatcttt    900
tgtacagaaa agcaagatga aaaggatgtg aaatggtaga tataccaaca aaacttcaga    960
ctgtaaaatt gccaggatgc agttttcccc ttgattggcg tgtgtgtata tatggataaa   1020
tatatatata cacacacaca tattactgca atctgtgatt gcttcatctg taaatcagtt   1080
gtaaaccttt acatatttga cttaaataac tgtaagatat atatgtacta cattaaaaag   1140
tgttgattaa tagatgaaat ttttaaatta attttttaaa acatgccata cattgtatca   1200
caatgttaat gtgccaagat attgttcctg tcatgcagag tataagaatg ctttgaacaa   1260
tttgtagact tagtgaaata aaataagagg aaagccaaaa acaaacaaac aaaargcata   1320
tgggggagct gggtattttc tctttagctt actgttgtgc ctttttattt ttcctatcac   1380
agccgttggg gtttgggggg ccccaat                                       1407

<210> 728
<211> 756
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (733)
<223> n equals a,t,g, or c

<400> 728
gccccactgc ttgggatggg gagttgcaac ttcagtgtgg aatttcctct ttgaggagcc     60
tgggcttgga tctatcctga tctggtgatg aagccatgat tactttagac ctagcccagg    120
cttggaggcc agctggagga agaagggtct aaatcctggc ctgtagagtt agaactacca    180
tttcctcccc ttagckgccc ttgtatgacc cggatttgck atgcaaaaca atctatccca    240
ggttctgttc tggttggcta cattgttcag caactcacaa aacgtagcac aaacattcat    300
tatggagaaa gcatcaggac tgttgagtaa ctcctccttt acttttttcc tgctggctac    360
agcatggggt gccctatagg caaagcccag ctgaagaaca gaatggaggg ctctgggagg    420
aggcagctca ctggagagcc tacattcctt acacaagtgc ctaaagagag tgatgctaac    480
actccatctg ccctgtccat tgccttcata tacagtctac ttcgtgttct gtcacccttt    540
ggggarggga gttctcctgg gacagtgggc tctgcatgtt ctccacttgg atacattttg    600
gggctargat carggcacta ttcctggagg gtccagtcat tcaccagcat ttgcaaatgt    660
ccatagggag caggtggcag cctctactcc cagcaacaag tttgtgttct ctccttttct    720
ctctttgcct cantctctcc agttgggttt cagctg                              756

<210> 729
<211> 1228
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1169)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1174)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1204)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1228)
<223> n equals a,t,g, or c

<400> 729
gcccccgcct cgcatgatgg ctgcggtgcc gccgggcctg gagccgtgga accgtgtgag     60
aatccctaag gcggggaacc gcagcgcagt gacagtgcag aaccccggcg cggcccttgg    120
ttgagcaatg tttaaagcgt ttgaaaaaca tgaatttgga gggctcaatt caagacctgt    180
ttgagttgtt ttcttccaat gaaaatcagc ccttaactac caaagtatgt gttgtcccca    240
gtcagccagt ggtggagttg gtgttgatga aggttttggg agcctgcaag ttgttgctcc    300
gcttgttgga ctgctgctgc aaaacttttc ttttgactgt gaaacatcta ggtttgcaag    360
agttcattat tttaaacctt gtgatggttg ggctggtgag caggttatgg gttctctata    420
aaggtgtctt aaaaaggttg attttgttat atgagccttt gtttggattg cttcaagagg    480
tcgctaggat tcaaccaatg ccttacttca aagattttac ctttccttct gatatcactg    540
aatttttagg acagccatat tttgaagcct ttaagaaaaa aatgcctata gcttttgcag    600
ctaaaggaat aaataaattg ctaaataaac tgtttttaat aaatgagcag tcaccaagag    660
ccagtgaaga aaccttgctt ggaatttcaa aaaaagctaa acaaatgaag atcaatgtac    720
agaataatgt ggwtcttggr cagccagtaa agaataagag agtcttcaaa gaagagtcat    780
cagaatttga tgtgagggct ttctgcaacc agctgaaaca caaagctact caggagacca    840
gttttgattt taaatgttct caatccagac taaagacaac caagtattct tctcagaaag    900
tgataggaac tcctcatgcc aaaagtattg tgcmaagatt ccgagaggct gagtccttca    960
cacaactttc tgaagaaatc cagatggcag ttgtatggtg caggagcaaa aaactcaagg   1020
ctcaggccat ttttctgggt aacaaacttc ttaaaagcaa ccggcttaaa catctgggaa   1080
gctcaaggta ctagtttggc caagaaacta gagtgcataa aacgtctatt tggcaacact   1140
tcttcggggt caggttccaa attcaagcnt catnggggca ggagtcccga taattttccg   1200
gggncaaggg accccgggaa gtgcgtgn                                      1228

<210> 730
<211> 716
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (400)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (626)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (645)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (655)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (705)
<223> n equals a,t,g, or c

<400> 730
tcttacgctt cccagtatat tcattgtcta taccgctgct tctatcgcca gtactttcgt     60
cgttactgcc gggatgttcg gcgcaatgag cctgtacggt tacaccacga agcgcgattt    120
aagtggcttt ggcaatatgc tgtttatggc gttaatcggc attgtgctgg catcgctggt    180
caacttctgg ttgaaaagcg aagcattgat gtgggcagtt acctacatcg gcgtgattgt    240
ctttgtcgga ttgacggcgt atgacacgca gaaactgaaa aatatgggtg agcagattga    300
tacccgcgac acgtcgaacc tgcgcaaata ttccattctt ggcgcgttaa ccttgtatct    360
ggacttcatc aacctgttcc tgatgttgtt gcggatcttn ggcaaccgcc gttaattctt    420
tttcaccatc actatcccgg ccatgtgtcg ggattttttt cttactaaaa acgacactta    480
acaagtacca ggtataaaat atgccttatg gacgagcgga aagcgttttc tgtatccata    540
aatgcaaaag ttattttgtt atgcgtgggt tttaaattta ttgatggttg aaatattaat    600
attttttcct aaggaataac taaaanaatg ggaatccata ctccnccaaa accangcaat    660
aaattaaatt tttccaccca caaaggcccg gatttttaaa cggtnattat gggctc        716

<210> 731
<211> 685
<212> DNA
<213> Homo sapiens

<400> 731
aaatttccag ggactatgtt cggagtgaac tggagtttgc ctatggaggg accaatgtat     60
ttagaacctc tctctatgaa tcggtttacc acagccttaa taggtcagtt ggtggtgtgt    120
actttatgct cctgtgctga aaacaaagca gatttggctg ttttcagctc acatgcttcc    180
tctgctagca cgactctgcc ttgttccttt ggagacaatt gttatcatca ataaatttgc    240
tatgattttt actggattgg aagttctcta ttttcttggg tctaatcttt tggtacctta    300
taaccttgct aaatctgcat acagagaatt rgttcaggta gtggaggtat atggccttct    360
cgccttggga atgtccctgt ggaatcaact ggtagtccct gttcttttca tggttttctg    420
gctcgtctta tttgctcttc agatttactc ctatttcagt actcgagatc agcctgcatc    480
acgtgagagg cttcttttcc tttttctgac aaggtaatta ataagagcct atgatacttt    540
atataacctt agaaagagaa aactttgatc taggaatagt aagttttgca gattactttt    600
atcgttcatg ttacacaact tcgtattttg ttaagatagg attttcattc actggatacc    660
taggtatggc aatgcaggga atgaa                                          685

<210> 732
<211> 1376
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (35)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (37)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (53)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (563)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1311)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1360)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1374)
<223> n equals a,t,g, or c

<400> 732
ttctcaaanc cattcagtga cangacacaa gtcancngac agtcacggtc ggnaattccc     60
gggtcgaccc acgcgtccgg ccaccgcatc ctcctcggct caggagatgg agcagcagct    120
ggctgaacgg gagtgtcccc ctcacgctga gcagaggcag cccaccaaga agatgtccaa    180
agtgaaaggt ctggtctcca gccgccacta gggccggctg gggcagctgg actcaccagg    240
cctgggtcag gtggggaggg gacaccaagg gcccatttcc tcccctctct acctgcagtg    300
agttccagac ctgcccgtcc cctcaccagc gcctccccac cctgttggta ctgttccaga    360
aaaactgtta ctccccctca cccactccct ccttccccag ttgttccctt cagactcagg    420
ggctccacca atgccatccc aaaacagggt cagacactgc ccagcttccc tccaggaggt    480
tcttgtctct gtgtaagggc ttgtytccct cccagttttt cttttgctcc acgtcatttt    540
gtcaggctgg ttataagccg gangcagctt taaccagccc ccagggatga ttgtgaagga    600
ggcccctccc cttgtgagga gggggcactc ctctccagcc cctggtacca cagtcctcac    660
gatggtgcag tgatttctag ccaggcgtca agatgcgctg ctttccctct cctgcctcat    720
cccttgttgg cagctccagt tcaggccgtg gagggacgtg atgctgggct gtgtttacta    780
aacccacggg ttttcagcct cttaagccca gctccgatct ccaattagtt gagagcgctg    840
ggttgactaa cctctggtat ctgagcacag acagagggtg ctgtgggtct gctgggtggc    900
agaaatggtt ccttccggct tggcgttctc tcctggccac tcttcctgct gcctctgact    960
actcagcctt gttttcggtg tgtaggcccc agctgcccac tggaactgcc ggctaatgct   1020
tgctctccca agatctttaa ctcctcctgg ctgcacctgg gtagggatgg tggcatcgat   1080
gcccctctgt ctgctgaagg acctgttgct gcttctgtct tttcacccct ccttggctga   1140
tgacccagag ccctctgatg atggcattct cctggcaaga gaaaaagact taactagact   1200
tctgaacttg aacagtttca ggttatattt taattttttt ttttttgtac aggttctgat   1260
tctaatacat ttcaacatgc ttttgtcaaa aaaaaaaaaa aaaaagggcg nccgctctag   1320
aggatccctc gaggggccca agcttacgcg tgcatgcgan gtcatagctc tacncc       1376

<210> 733
<211> 686
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (657)
<223> n equals a,t,g, or c

<400> 733
cagttcttgt gtataattta ccagtatgtt ggtcaggaaa catgccagat ccccacaacc     60
ttccaatagt ggctggttgg aagaaatacc cactcttttt tggtactgct gtatttgctt    120
ttgaaggcat aggagtggtc cttccactgg aaaaccaaat gaaagaatca aagcgtttcc    180
ctcaagcgtt gaatattggc atggggattg ttacaacttt gtatgtaaca ttagctactt    240
taggatatat gtgtttccat gatgaaatca aaggcagcat aactttaaat cytccccaag    300
atgtatggtt atatcaatca gtgaaaattc tatattcctt tggcattttt gtgacatatt    360
caattcagtt ctatgttcca gcagagatca ttatccctgg gatcacatcc aaatttcata    420
ctaaatggaa gcaaatctgt gaatttggga taagatcctt cttggttagt attcttgtgc    480
cggagcaatt cttattcccg tttrgacatt gtgatttctt cgttggagct gtgagcagca    540
gcacattggc cctaatcctg ccacctttgg ttgaaattct tmcattttsg araggaacat    600
tatatrttgg tggycctgaa aaaatattct wtrcattcct grrttttgtt tgggctnctt    660
aattaggttc catattatac cttttt                                         686

<210> 734
<211> 1340
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1164)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1226)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1238)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1243)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1282)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1311)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1316)
<223> n equals a,t,g, or c

<400> 734
ggagcgccgg ggcagggagg cgggcaccag gcgcgggtcc ctccgggcag gggaggtagg     60
cctgggcctg acgccggcca cgcagcggcg ggagagtgag cactcgggcg gcggcgtcct    120
ggagacccgc gagagatgga agcggcggcg acgccgrcgg ctgccggggc ggcgaggcgc    180
gaggagctag atatggatgt aatgaggccc ttgataaatg agcagaattt tgatgggaca    240
tcagatgaag aacatgagca agagcttctg cctgttcaga agcattacca acttgatgat    300
caagagggca tttcatttgt acaaactctt atgcaccttc ttaaaggaaa tattggaact    360
ggccttttag gacttccatt ggcaataaaa aatgcaggca tagtgcttgg accaatcagc    420
cttgtgttta taggaattat ttctgttcac tgtatgcaca tattggttta aaaagtcaac    480
attaggttat agtgacactg tgagctttgc tatggaagtg agtcttggag ttgtcttcag    540
aagcaagcag catgggggcg gttcatgaag gattcctgga gagtaaagtg tttatttcaa    600
atagtaccaa ttcatcaaac ccttgtgaga gaagaagtgt tgacctaagg atatatatgc    660
tttgctttct tccatttata attctttggt cttcattcgt gaactaaaga atctawttgt    720
actttcattc cttgccaacg tttccatggc tgtcagtctt gtgataattt accagtatgt    780
tgtcaggaac atgccagatc cccacaacct tccaatagtg gctggttgga agaaataccc    840
actctttttt ggtactgctg tatttgcttt tgaaggcata ggagtggtcc ttccactgga    900
aaaccaaatg aaagaatcaa agcgtttccc tcaagcgttg aatattggca tggggattgt    960
tacaactttg tatgtaacat tagctacttt aggatatatg tgtttccatg atgaaatcaa   1020
aggcagcata actttaaatc ttccccaaga tgtatggtta tatsaatywg tsaawattag   1080
tytatatatt ttataatgta ccactgtttg atgataaagt cgtgttcttg gatttatggt   1140
ttaaacattt aaaattttta ctgngatttc ctggaatccc atcactttgg gaggcagaag   1200
tgggccggat cacctgaggc gggagntcaa agaccagnct ggncaacata atgaaacccc   1260
atctgtacta aaaatacaaa antagccagc gtggtggcgg gtgcctatat nccagntact   1320
aagaggctga agcaggagaa                                               1340

<210> 735
<211> 602
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (482)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (508)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (576)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (580)
<223> n equals a,t,g, or c

<400> 735
ggccagcagg aaaacagtgc tgaaayccct acattcagta atcattcagc tctttaagcc     60
atggatcctg gttttagagg acaacgaaag cagccaacag cggcattacc cctggctaga    120
gagtgatact gtggtggcct caagcattgt gcagctgttc actgactgta ttgactcact    180
gcatgagagt tttaaagata agctgttgcc aggtgatgca ggagcccttt ggttgcacct    240
gatgcattat tgtgaagcat gtacagcacc caaaatgcca gagttcattc tgtacgcttt    300
ccatagcacg taccggaaac tgccatggaa ggacctgcac cctgaccaga tgctcatgga    360
ggccttcttc aaagtggaac gaggaagccc caagagctgt ttcttatttt tggggtctgt    420
actctgtgaa gtcaactggg ttagtgtgct ctctgatgcc tggaattcca gtccccaccc    480
anaaacccgc agcatgattg tctgcctnct tttcatgatg attttattgg caaaggaagt    540
tcaactggta naccaaacag attcaccttt acttannctn cttggacaga caagctcact    600
tt                                                                   602

<210> 736
<211> 643
<212> DNA
<213> Homo sapiens

<400> 736
ttttttgaga tggagtctta ctccagcctg ggtgacaaga ataaaacacc accatctcaa     60
aggaaaaaaa aaaaaaaaaa aaaaaaaaga actttcacat tctttgggac acatcatttg    120
gctgcccact tgctttctgc attctttttt tctctttara attcttagcg tcaagttggg    180
aatgacggaa acaccaattt atgtcccaaa ttcttcccct ttctggcaca ctgctttatt    240
ataggcggtt cccaggtctt atgctgttat cattcaaact gcagattaca agttgcacag    300
tcagcaggaa tgaaaaggat caacagagtc ttttgttttt tccagcaaat atcctgagtt    360
tccagttagc catgcaggga aacacagtca ttttcatagt attcactgtg gtggctttcc    420
tctggatcac atcccaggct gcctcaaacc tgttggtatt tgtggcggtc atcccagagt    480
ccaaggtttc ttcttcgtca gaaagccttg gttcctgttc tgagaacagc attttcctat    540
ttgtttttct ccagcagtgc aaagttcctt tcccttttct gggttacact gcttcttttt    600
tttttttttt tttatttttg gtaaacagag tgagaccctg tct                      643

<210> 737
<211> 1116
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1082)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1103)
<223> n equals a,t,g, or c

<400> 737
ggcgcgctcc aggccggtcg ctccaccccc cggctcccgg gactgtggac tccacgaccc     60
tgtcctcggc cctgtccgcg ccgaagcagc ccgggactgc gcangccccg cgtgccgaca    120
tgggaaagtc tctttctcat ttgcctttgc attcaagcaa agaagatgct tatgatggag    180
tcacatctga aaacatgagg aatggactgg ttaatagtga agtccataat gaagatggaa    240
gaaatggaga tgtctctcag tttccatatg tggaatttac aggaagagat agtgtcacct    300
gccctacttg tcagggaaca ggaagaattc ctagggggca agaaaaccaa ctggtggcat    360
tgattccata tagtgatcag agattaaggc caagaagaac aaagctgtat gtgatggctt    420
ctgtgtttgt ctgtctactc ctttctggat tggctgtgtt tttccttttc cctcgctcta    480
tcgacgtgaa atacattggt gtaaaatcag cctatgtcag ttatgatgtt cagaagcgta    540
caatttattt aaatatcaca aacacactaa atataacaaa caataactat tactctgtcg    600
aagttgaaaa catcactgcc caagttcaat tttcaaaaac agttattgga aaggcacgct    660
taaacaacat aagcattatt ggtccacttg atatgaaaca aattgattac acagtaccta    720
ccgttatagc agaggaaatg agttatatgt atgatttctg tactctgata tccatcaaag    780
tgcataacat agtactcatg atgcaagtta ctgtgacaac aacatacttt ggccactctg    840
aacagatatc ccaggagagg tatcagtatg tcgactgtgg aagaaacaca acttatcagt    900
tggggcagtc tgaatattta aatgtacttc agccacaaca gtaaaaactg ggaaggagat    960
ggrtttaaag aaggaaatat ctattgatat ttcctattac ttctycaatg gaagrgggta   1020
tttcccaata gggagaccct taawttgaac caaacctaaa gtttacactt cttaggggta   1080
cngtttaaar gtttgtgggg ccntgccgtt tctttg                             1116

<210> 738
<211> 2431
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2366)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2383)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2400)
<223> n equals a,t,g, or c

<400> 738
gcacaggttc tcsgtcgctt ccctcttctc tcgccgcctc ctggcctccg caccgacgcg     60
gcccgggctg gagccgagcc ggggccgagc tgcaggccgg accggagccg gatctgtacc    120
cgctgagacg tggaaacatg gaggcctgag ccggtgtgcg ccacctgggc tgcggcggcg    180
acagsgactt ctcctgaccc ctctgccacc ctcccatccg tccgcgggtc cgtggagctg    240
gagcagatcc cccagccggc tgagacaggt tgtcttttgg aaatgcaggt ttaaggacaa    300
attatctgct taagctagaa gatgggatcg aatagcagca gaatcggcga tcttcctaaa    360
aatgagtact tgaaaaagtt atcaggcacg gaatctatct ctgagaatga cccgttctgg    420
aatcagcttc tctcattttc tttccctgca ccaactagca gtagtgagtt gaaactcttg    480
gaggaagcaa ccatttcagt ctgcaggtca ttagttgaaa acaatcctcg aacaggaaat    540
cttggtgcac taattaaggt cttcctttct agaaccaaag aactaaaact ttcagcagaa    600
tgtcagaacc acatcttcat ttggcagaca cacaatgctt tgtttattat ttgctgtttg    660
ctgaaagtgt tcatctgtca gatgtcagag gaggaattac aacttcattt tacttatgaa    720
gaaaaatctc ctggcaatta cagttctgac tcagaagatc ttttggaaga attgctgtgc    780
tgtttgatgc agttgatcac tgatattcca ctcttagata ttacatatga aatatcagta    840
gaagctatat caacaatggt tgktttcctt tcctgccaac tcttccacaa agaagttttg    900
cgacagagca tcagccacaa gtatttgatg cgaggtccat gtcttccata caccagcaaa    960
cttgtgaaga ccttattata taactttatc agacaagaaa agccacctcc tccaggggcc   1020
catgttttcc ctcagcagtc ggatggggga ggactgcttt atggacttgc atcaggagta   1080
gcaacaggac tctggactgt cttcacacta ggtggtgtgg gcagcaaagc ggctgcctct   1140
ccagagcttt cttcccctct ggccaaccag agtctcctgc ttctgctggt gttggccaat   1200
ctgacagatg cctcagatgc gccaaacccc tacagacaag ccattatgtc cttcaagaac   1260
acacaagata gcagtccttt cccctcatca attccacatg ccttccagat caactttaat   1320
agtttgtaca cagctctttg tgaacagcag acatctgatc aagcaactct cctcttgtat   1380
accttgctcc atcaaaatag taatattaga acatacatgt tggctcgcac agatatggaa   1440
aatcttgttt taccaattct tgagattctg tatcatgttg aagaaaggaa ttcacaccat   1500
gtgtatatgg cccttataat attgttgatc cttacggaag atgatggctt caacagatcc   1560
attcatgaag tgatactaaa aaatattact tggtattcag aacgagtttt ttatccccta   1620
tgtctggtct cttgtctaca actcagcagt cggcctgtac tggaatccac aggacatcca   1680
gctgttcacc atggattccg actgagggca ggatgctctc ccacccggac ccctccagcc   1740
aagcagccct tcaagttctt ttatttctgg gtaacagaag tagacagaca ggttacttgg   1800
tgtatcttct gttaaagagg attgcacgag tgtgttttcc tcacacactt tgatttggag   1860
aattggtgct agttggcaat agataactca gcgtagatag tattgcaaaa aggggaggaa   1920
atacacaaca ataataaatg taaaaacctg ctattcaaca tgcagtttta tttcgaagcc   1980
aaaaatctag agctttccca agatcctgtt gccttaggca catcacactt caacagtgca   2040
cactatccaa cagtgcacac tattcaacag tgcacactat tcaaaagcgt agactatttt   2100
tttgcatgtt caagatattt gttttggtct tatgtgtgtg tgagagagag agattccttt   2160
gacattaagg agcatcaatg agaaaagatg atgaggcagg aattaataaa gaaatgaagt   2220
cgtgtgtgtt tggttgcctg tcagagggca cacaatttca taaacaccat gcctggacaa   2280
tttgatatta atatttaaca cctctgcatc tttttcctta aaaaagaata tgggccagat   2340
acagtggctc acatttgtta tccccngcac ttttggggag ccnagttagc agaatccccn   2400
tggagcacag gaatctgaaa ccagcttggg c                                  2431

<210> 739
<211> 1227
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (939)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1134)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1209)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1213)
<223> n equals a,t,g, or c

<400> 739
ggcacgtcaa ccccttcctc ccgtatatca gtgatacggg aacaacacct ccagagagtg     60
gtatttttgg atttatgata aacttctctg catttcttgg tgcagccacg atgtatacaa    120
gatacaaaat agtacagaag caaaatcaaa cctgctattt cagcactcct gtttttaact    180
tggtgtcttt agtgcttgga ttggtgggat gtttcggaat gggcattgtc gccaattttc    240
aggagttagc tgtgccagtg gttcatgacg ggggcgctct tttggccttt gtctgtggtg    300
tcgtgtacac gctyctamag tccatcatct cttacaaatc atgtccccag tggaacagtc    360
tctcgacatg ccacatacgg atggtcatct ctgccgtttc ttgcgcagct gtcatcccca    420
tgattgtctg tgcttcacta atttccataa ccaagctgga gtggaatcca agagaaaagg    480
attatgtata tcacgtagtg agtgcgatct gtgaatggac agtggccttt ggttttattt    540
tctacttcct aactttcatc caagatttcc agagtgtcac cctaaggata tccacagaaa    600
tcaatggtga tatttgaaga aagaagaatt cagtctcact cagtgaatgt cgcaggccat    660
ttctaaaagt gctacagagg acagacaggg ttttgaggcc accctgatta ttgggatgca    720
tctgcagcac atccaggact tgaatttcat tacgagttcc taatagttgt atttctaaag    780
atgtgtttcc tagagaatgt acagccttat gacactgtag tgatgttttt ataattttct    840
aagtagattt ttttatatta acaaattcat atacagaaaa aataaggtgt tacaaaaaat    900
ggagagctct tatttttgta cagattctgt cgtttttknt ttatttgtgt gagatttatg    960
gaaatacact aaatkagtaa ttcaggttca gtacatttat tacaaagtga aatcagggga   1020
tattcatttg taaattttat tcttagtgaa tgaactgtat watttttttt atcaaggaga   1080
gcacttataa aattcaattt ataaagatca tatcccaaat cataaagatt tagntgatca   1140
ttaacactaa gatactctga ttttagccga actaacaaag gcttctactg ggagggctta   1200
tccacatgnc agnactctaa gtgaatc                                       1227

<210> 740
<211> 1243
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1001)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1234)
<223> n equals a,t,g, or c

<400> 740
ttcatgtttt ctgcggatcg tttggttttg cctgaggatt tattccaaaa gagcatagac     60
aactcctgtt ctgcttttca tcatcagact tgttgtggaa gagggattga atcagctgcc    120
atataaagaa tgcatggtga ccactccaac agggtacaag tatgaaggag tgaaatttga    180
gaagggaaat tgtggggtca gcataatgag aagcggtgag gcaatggaac aaggtttacg    240
agactgctgt cgatccatac gaattggaaa gatcctgatt cagagtgatg aggagacaca    300
aagagccaaa gtatattatg ccaaattccc cccagacatt taccggagaa aagtccttct    360
gatgtatcca attctcagca ctggaaatac tgtaattgaa gctgtaaagg ttcttataga    420
acatggagtt caacccagtg ttatcatcct actcagtctg ttctccactc ctcatggtgc    480
caaatcaatc attcaggagt ttccagagat cacaatttta actactgaag ttcatcctgt    540
tgcacctaca cattttggac agaaatactt tggaacagac taagttattt aagtaaaata    600
attgtcttat gtaatattac aatcatgttt tgattttcta tttgttttac tgattcactt    660
gagggtggca gagaaaaatg tgttaaaatg ctttttagtt ttggaagtgg gtatatttga    720
ggttatatct cayttagtta tttgtttact gttggcaccg aattcaacaa tgaagtatat    780
gcaactctta caaaacataa attttaataa tattctaatg caaattactg aaccctcagt    840
gcattaaaat tatttcctaa tttatgagcc tcttagtttg gaggttgctt gaagccacaa    900
ataaaactca aatgagagtc agttctttgt cccactgtag tttgcatttt gtttagtttg    960
gttttagctc tactaaggtt tcacatatgt ggctattgcc nattcctcta ctgttttctt   1020
tctgatactg gacatgctag taacttggag aggagaataa aagaatgtct cctggaattt   1080
tacattccca ttaatgtcct cattcaattg gcagacctag gatgtatggg ttaactctca   1140
ggccattatg tttttcatgg stcatttccc aaactgcatt gttggkargt gccttgctaa   1200
gctgtaatgc agtaagragg gtgggcattt tagnaattgg act                     1243

<210> 741
<211> 1000
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (995)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (997)
<223> n equals a,t,g, or c

<400> 741
ggccccgggg cgcagcgcgc acgcaatcgc gtttccggag agacctggct gctgtgtccc     60
gcggcttgcg ctccgtagtg gactccgcgg gccttcggca gatgcaggcc tggggtagtc    120
tcctttctgg actgagaaga gaagaatgga gaagcccctc ttcccattag tgcctttgca    180
ttggtttggc tttggctaca cagcactggt tgtttctggt gggatcgttg gctatgtaaa    240
aacaggcagc gtgccgtccc tggctgcagg gctgctcttc ggcagtctag ccggcctggg    300
tgcttaccag ctgtatcagg atccaaggaa cgtttggggt ttcctagccg ctacatctgt    360
tacttttgtt ggtgttatgg gaatgagatc ctactactat ggaaaattca tgcctgtagg    420
tttaattgca ggtgccagtt tgctgatggc cgccaaagtt ggagttcgta tgttgatgac    480
atctgattag cagaagtcat gttccagctt ggactcatga aggattaaaa atctgcatct    540
tccactattt tcaatgtatt aagagaaata agtgcagcat ttttgcatct gacattttac    600
ctaaaaaaaa aaagacacca aatttggcgg aggggtggaa aatcagttgt taccattata    660
accctacaga ggtggtgagc atgtaacatg agcttattga gaccatcata gagatcgatt    720
cttgtatatt gattttatct ctttctgtat ctataggtaa atctcaaggg taaaatgtta    780
ggtgttgaca ttgagaaccc tgaaacccca ttccctgctc agaggaacag tgtgaaaaaa    840
aatctcttga gagatttaga atatcttttc ttttgctcat cttagaccac agactgactt    900
tgaaattatg ttaagtgaaa tatcaatgaa aataaagttt actataaata ataaaaaaaa    960
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaananaaa                         1000

<210> 742
<211> 1236
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (987)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1047)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1060)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1126)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1130)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1207)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1210)
<223> n equals a,t,g, or c

<400> 742
ggcacgagcg gagatgagcg gggcgtggga cgtgctgcgg cgtcctagct ggcttacagg     60
gcggcggcgg ggtgtgtgtc ctctgttaag agtgctactc gcccggggtt gatctgtgca    120
tgccactcct gggtcagacg gtgaggtcgg cgtctgcgag gacgcggcgg tggagtagaa    180
gggcagccgg agacaggccc ggcgcccctt ccgaggctag acggccccag cttcgcgggg    240
atcatggcat tgctggtgga ccgagtgcgg ggccactggc gaatcgccgc cgggctcctg    300
ttcaacctgc tggtgtccat ctgcattgtg ttcctcaaca aatggattta tgtgtaccac    360
ggcttcccca acatgagcct gaccctggtg cacttcgtgg tcacctggct gggcttgtat    420
atctsccaga agctggacat ctttgccccc aaaagtctgc cgccctccag gctcctcctc    480
ctggccctca gcttctgtgg ctttgtggtc ttcactaacc tttctctgca gaacaacacc    540
ataggcacct atcagctggc caaggccatg accacgccgg tgatcatagc catccagacc    600
ttctgctacc agaaaacctt ctccaccaga atccagctca cgctgattcc tataacttta    660
ggtgtaatcc taaattctta ttacgatgtg aagtttaatt tccttggaat ggtgkttgct    720
gctcttggtg ktttarttac atccctttat caagtgtggg taggagccaa acagcatgaa    780
ttacaagtga actcaatgca gctgctgtct accaggctcc gatgtcatct gscatgttgc    840
tggktgctgt gcccttcttt gagccagtgt ttggagaagg aggaatattt ggtccctggt    900
cagtttctgc tttgtcgacc aggctggaat gcagtggcac aatcatggct cactgcagcc    960
tcagcctcct gggctcaagc aatcctnctg cctcaacctc cccagtagct gggactacag   1020
gtgcacacca acatatctgg ctgattntta tattttttgn agagacagag ttttgccatg   1080
gtgctcaggc tgatctcaaa ctcttgagct caagccatct gtctgncctn agccttttcg   1140
aagtgctggg aatacaggcc tgagccacca acacctgggc cagtaaattt cttaaatccc   1200
taacttnccn tggtttctaa ttggccttaa ccccgg                             1236

<210> 743
<211> 1161
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (960)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (976)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1003)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1012)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1048)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1066)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1115)
<223> n equals a,t,g, or c

<400> 743
gtctctctct ctctctctct ctctcccttg tgcccgcttt ctgccatccg cgctgtctcg     60
tgtctccctt tttccattaa atgcctcttt tcttgcgggt ctcatstcgg gaatagtgca    120
ctacggggac atacctatcc ccaactatcc taggcccgag aaccagccct tgccttcgcg    180
taacaggcgg agactcgctg aggcgagttg cacttctaat tgggcgtgag gtcttgtcaa    240
tccccaagtt cttccaatca gaagtccggt ccatccagcc ttccgctccc cattggcctg    300
tgtggaggaa gaggggtggg taagccgaag tcgctgcgct cagtgcgcag gcgcgaagaa    360
gctggcaggg gcacgagccg ggggcgggtt tgaagacgcg tcgttgggtt ttggaggccg    420
tgaaacagcc gtttgagttt ggctgcgggt ggagaacgtt tgtcaggggc ccggccaaga    480
aggaggcccg cctgttacga tggtgtccat gagtttcaag cggaaccgca gtgaccggtt    540
ctacagcacc cggtgctgcg gctgttgcca tgtccgcacc gggacgatca tcctggggac    600
ctggtacatg gtagtaaacc tattgatggc aattttgctg actgtggaag tgactcatcc    660
aaactccatg ccagctgtca acattcagta tgaagtcatc ggtaattact attcgtctga    720
gagaatggct gataatgcct gtgttctttt tgccgtctct gttcttatgt ttataatcag    780
ttcaatgctg gttatggagc aattcttatc aagtgggttg gctgattcca tcttctgtta    840
ccgayttttt gacttcgkcc tcagttgcct ggttgcyatt agttctctca ccwatttgcc    900
aaagaatcaa agaatawctg gatcaactac ctgattttcc tacaaagatg acctcctggn    960
cttggacttc agctgncttc tggtcatggt cttgggtctt tgnctaatca tnattttaag   1020
cttatctaaa taactgggtt tggactgnta taaatacatc aacaanccga acgtgccgga   1080
aaatgcttgg gaccctggct ttgaacacct cttanacgtt ttgcaaccta tgaaatggcc   1140
gggaaaagcc cgaaaaaaac c                                             1161

<210> 744
<211> 1459
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (25)
<223> n equals a,t,g, or c

<400> 744
gcggacgcgt gggaagacga caganggggt ttgaagacgc gtcgttgggt tttggaggcc     60
gtgaaacagc cgtttgagtt tggctgcggg tggagaacgt ttgtcagggg cccggccaag    120
aaggaggccc gcctgttacg atggtgtcca tgagtttcaa gcggaaccgc agtgaccggt    180
tctacagcac ccggtgctgc ggctgttgcc atgtccgcac cgggacgatc atcctgggga    240
cctggtacat ggtagtaaac ctattgatgg caattttgct gactgtggaa gtgactcatc    300
caaactccat gccagctgtc aacattcagt atgaagtcat cggtaattac tattcgtctg    360
agagaatggc tgataatgcc tgtgttcttt ttgccgtctc tgttcttatg tttataatca    420
gttcaatgct ggtttatgga gcaatttctt atcaagtggg ttggctgatt ccattcttct    480
gttaccgact ttttgacttc gtcctcagtt gcctggttgc tattagttct ctcacctatt    540
tgccaagaat caaagaatat ctggatcaac tacctgattt tccctacaaa gatgacctcc    600
tggccttgga ctccagctgc ctcctgttca ttgttcttgt gttctttgcc ttattcatca    660
tttttaaggc ttatctaatt aactgtgttt ggaactgcta taaatacatc aacaaccgaa    720
acgtgccgga gattgctgtg taccctgcct ttgaagcacc tcctcagtac gttttgccaa    780
cctatgaaat ggccgtgaaa atgcctgaaa aagaaccacc acctccttac ttacctgcct    840
gaagaaattc tgcctttgac aataaatcct ataccagctt tttgtttgtt tatgttacag    900
aatgctgcaa ttcagggctc ttcaaacttg tttgatataa aatatgttgt cttttgttta    960
agcatttatt ttcaaacact aaggagcttt ttgacatctg ttaaacgtct ttttgttttt   1020
ttgttaagtc ttttacattt taatagtttt tgaagacaat ctaggttaag caagagcaaa   1080
gtgccattgt ttgcctttaa ttggggggtg ggaagggaaa gagggtactt gccacatagt   1140
ttccttttta actgcacttt ctttatataa tcgtttgcat tttgttactt gctaccctga   1200
gtactttcag gaagactgac ttaaatattc ggggtgagta agtagttggg tataagatct   1260
gaacttttca tctgcagagg caagaaaaat atttgacatt gtgacttgac tgtggaagat   1320
gatggttgca tgtttctagt ttgtatatgt ttccatcttt gtgataagat gatttaataa   1380
atctctttaa atactaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1440
aaaaaaaagg gcggccgct                                                1459

<210> 745
<211> 1623
<212> DNA
<213> Homo sapiens

<400> 745
cccccctcga gttttttttt tttttttttt tttttttttt tttttttttt tttttttttt     60
ccaaatcacc aatacattta tttgcgggag atgaggtcaa atcttaccat gaactttaaa    120
actgggtagg actagagaca ctgatctgcc caacctctgg gtattcacaa ctgcacaggt    180
aaccagatcc tgtacgcgag gcatcaccat taaacagatg agcattagat gaggaggaca    240
cattctgagt agttgcatga tttcccattc agaggcaggt gctgccctca tatcagaaaa    300
gtagtgttga gaaaaacaca ggcagagcct ggccatttgc ctcctagcat aggcctagac    360
atgatggtgg ccacgtgcca ggggaccaca ccctatgtac aaagcaggag aatgatgctc    420
ccagctgagc tgcaggatgg gcgctgggct gactggaggg gtagacgggg tggggtctga    480
ccccattagc ctttccccat ccaacctggg cccccataag ccattctctg gccctctgca    540
caagacagac tcagcaaatc tgcgaggtat ggggattctg ccaactcccc acctcgcctc    600
accttcccta ggtctgccgg gtgacccaat ccactgggtg cagccccacc cccgctcaac    660
cccacatctg gacagacaca tggcaaatat ggaactgaag cccggctggg ctggagcaca    720
tctggttgtt gttgggttgg agtcgtcttg caggtgtccc aaggtggtca ggcctcaccc    780
acggtggcca ggttgagacc gtgtttttta gatgattcag gttactccag ggcaaagcat    840
gatcctgatg acacccggcg gaaaagcagg ctggagcctc ggaagagctg gccctgcaca    900
ctcaggtact tccagcagtg aatccaggat ttgaacactg gggagtaagg ggggagccca    960
gcttgcagcc cgcagttgtt cacagccatg aggtcgccaa ctagcaggaa ggggtaggtc   1020
agcatgctca ctgcaatccc catcacgaac ttggtatagc tccggatggc cagggcctgg   1080
ctgaactggg aacctggatt ctggtcgttt cccagccccc ctggggtgtc actcacgctg   1140
tcatccacca ggtaggcatt gatgaagtgg gccagcaggt tacagcccca caagaaaacc   1200
acatcgccca ggaggtgagg gattaatcca acgaagaatc ccagcagccc ttcctctttg   1260
aaaatcttcc caatggagct cagcacacca ctgtacttgg cctcccgtcc cacaaactgg   1320
accatgcagc gcattgagat gacatgcagg gggtgggcca acatgcggga cacacactgc   1380
atcatcatct cgtaggaggt ctccttcaca actttcttca gggaagtctt catatcatcc   1440
ttgttggaaa cctgctcaat ctcatctgga gggaaaacct tcttcatgct accccgagtc   1500
acagtagaga gggcgttgga catcagccgg ggactcaggc ctcggaacag ccctatctta   1560
ccatccactt gcacgatgta cttggcgtag gtgaagaagc tcggcagata gaggacactg   1620
ggg                                                                 1623

<210> 746
<211> 603
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (435)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (484)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (570)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (580)
<223> n equals a,t,g, or c

<400> 746
caccctgatg cattaatgcc tgatggccag ttgggacgga ggcaagacag tgggtntgac     60
tcattgggaa gatttaaaga ggaaggctgt gggattcttc gttgattaat ccctcacctc    120
ctggcgatgt ggtttcttgt gggctgtaac ctgctggcca cttcatcaat gcctacctgg    180
tggatgacaa gcgtgagtga caccccaggg gggctgggaa acgaccagaa tccaggttcc    240
cagttcarcc aggccctggc catccggagc tataccaagt tcgtgatggg gattgcagtg    300
agcatgctga cctacccctt cctgctagtt ggcgacctca tggctgtgaa caactgcggg    360
ctgcaagctg ggctyccccc ttactyccca gtgktcaaat cctggattca ctgctggaag    420
tacctgagtg tgcanggcca gctcttccga agctccagcc tgcttttccg ccgggtgtca    480
tcangatcat gctttggcct ggaattacct gaatcatctt aaaaacacgt ctcaacctgg    540
ccaccgtggt taaggcttaa cacttgggan actgcaaaan aatccaacca acacaacaaa    600
ttt                                                                  603

<210> 747
<211> 1080
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1015)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1017)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1025)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1056)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1066)
<223> n equals a,t,g, or c

<400> 747
gtcggacccg gaagtggcgc cctgggctcg cggcggtgcc gcggggatgg cgggagccgg     60
agctggagcc ggagctcgcg gcggagcggc ggcgggggtc gaggctcgag ctcgcgatcc    120
accgcccgcg caccgcgcac atcctcgcca ccctcggcct gcggctcagc cctcggcccg    180
caggatggat ggcgggtcag ggggcctggg gtctggggac aacgccccga ccactgaggc    240
tcttttcgtg gcactgggcg cgggcgtgac ggcgctcagc catcccctgc tctacgtgaa    300
gctgctcatc caggtgggtc atgagccgat gccccccacc cttgggacca atgtgctggg    360
gaggaaggtc ctctatctgc cgagcttctt cacctacgcc aagtacatcg tgcaagtgga    420
tggtaagata gggctgttcc gaggcctgag tccccggctg atgtccaacg ccctctctac    480
tgtgactcgg ggtagcatga agaaggtttt ccctccagat gagattgagc aggtttccaa    540
caaggatgat atgaagactt ccctgaagaa agttgtgaag gagacctcct acgagatgat    600
gatgcagtgt gtgtcccgca tgttggccca ccccctgcat gtcatctcaa tgcgctgcat    660
ggtccagttt gtgggacggg aggccaagta cagtggtgtg ctgagctcca ttgggaagat    720
tttcaaagag gaagggctgc tgggattctt cgttgtacgt gagtttatac accccataac    780
tggccacggg catggctctg ctaacaggtg tgtcctcaac ctctcagacc gcagctgctg    840
gcctgggact tcactacatg gccctgccct acctgagtgc tgcagccagc tctccagagc    900
tccatagcgt gtccaagctg cttagccctt ttcaggccat ggctcatgta aaaatggaac    960
tgtgtgtcta gtacatgggg gagatgaact tgaccaagcc ccactgggcc tcatncnttt   1020
gtggngggtg tggggctggt ctttattgag ctaatnactg cataantcct tggcttactg   1080

<210> 748
<211> 795
<212> DNA
<213> Homo sapiens

<400> 748
gggaatagtg aaaaggctca gaccgaccga tggcaagatc tgcaagcgtc tcaaagccca     60
ggcagaaagg gacttttctt ttattggaag aagtaaacat ggctagaaag aaccacgttc    120
agggaatgac gttgtgccca gccttttttt tttttttttt ttttttgtct ccccacctcc    180
tgcaatacgc ctttccaatc tttattggaa gtctctccct gcctacttcc taatttattc    240
ttatttgaca gagggtatgg aagacttgca atttgaaaac tggggaccag ttccaaagtc    300
agtaattgtg ttaaccacgt gtataacagc tctgctggac acccaagaaa gccatgggaa    360
cgccaactgg aaaggtcccc ttccccaggg gagcctgcga aggagaggtt ctgtagaatc    420
caagcccaca tttccaaagt cacccccaac gcgtcctctc acaccgtcca ctgtgcgttt    480
gtatgtgtct gggatccagg gcaatgtgaa ttttcttttt atttgggaga ttgttcacgg    540
aaaacagatc ttcttctctc ttgtccacct attaattgtt tacaatattt gtacatctat    600
gcaaaatact tgaatgggcc atggtgcctt ttttccttgt tagtatttaa ttaaaaatga    660
attgtttgtc atttgcaatg ttatctggtt tggcagctct ttattgtgtg tttgttgtaa    720
tgtcctactg ctcagattag ataggattca tgacgtggac ttcagaaaga gttcccacaa    780
ggatggtcag ttcaa                                                     795

<210> 749
<211> 476
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (380)
<223> n equals a,t,g, or c

<400> 749
gcggacgcgt gggcgaagcc gctgcgctcg cgcccggatc cctcaggcgg ctgcaggctt     60
cagcctgcgc tggttggtga aacagagatg tcagaaaagg agaacaactt cccgccactg    120
cccaagttca tccctgtgaa gccctgcttc taccagaact tctccgacga gatcccagtg    180
gagcaccagg tcctggtgaa gaggatctac cggctgtgga tgttttactg cgccaccctc    240
ggcgtcaacc tcattgcctg cctggcctgg tggatcggcg gaggctcggg gaccaacttc    300
ggcctggcct tmgtgtggct gctcctgttc acgccttgcg gctacgtgtg ctggttccgg    360
cctgtctama aggcttccgn agccgacagc tcctttaatt tcatggcgtt tttcttcatc    420
ttcggagccc agtttgtcmt gaccgtcatc caggcgattg gctctccggc tggggc        476

<210> 750
<211> 687
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (262)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (597)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (622)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (653)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (661)
<223> n equals a,t,g, or c

<400> 750
ggcacgagct cagctgagct gaagctggat tattaaagtg gattgtcact cagactctcc     60
gtgctacgct tatttggaga ctagaggagt gggagttgag cctggcttga acctttggaa    120
ccagaaaagt tggggagcag gtggaggagg ccacactcct gggagctgat ggttttaaat    180
ctggttttaa atctcttctc tgtctcaagt ccatgtctga agtgggtgaa gggtggactg    240
gatcctcaag cagaaggtca cnttctccca cccctagtcc tccacctggg aaatggcctc    300
aacggtcttc cctctttcca tccccagaat gggtgtcccg ctctgccttc agagatcctg    360
ttctgcactg ggccacyttc agagctgctc tgggcagaca aagctgtttc tcamcctccc    420
aaaatccctt cccatcccct ctcaggagct gcaaagagaa gggcacagtc tatatcttat    480
cacccttcat catccacttc tcagcagtcc ctggtattac ttggttgtgg aacatattat    540
caggaaaaaa gatttatcca ttgaaaaaat tggaaaagtc aaagtctggg ccgggtngca    600
gcgggtttca catctgtatt tnccagcatt ttggggaggg ccaagggcag gtngggttca    660
nttgagggtc agagtttcag ggaccag                                        687

<210> 751
<211> 5141
<212> DNA
<213> Homo sapiens

<400> 751
tcgatccacg cgtccgcgga cgcgtgggcc ggacgcgtgg ggtttctctt ccctctccat     60
tggaaatcyt gctccggagg tccraaacac gtattttaag cgtgcccttc ctcacctcct    120
ggagcaccct tagaagtatt gcctacttat ccgggctgag aatccttcat ttttgacctg    180
gctttttttt cgccctttgg gagataaagg tccctctcca ccctctacta acactctgca    240
cccaaggcct tatcctttgg ggtcaccagc tccttggcca tttctatgtg atttccccca    300
cccatctgag ttccagtttc ctctgggctc caatctccag tccctggcgg atctggtcag    360
tcccacccct aggtggagtg accagggggc tctggcccag gattcccaac cctggaaggc    420
agctccaagg caggaagaga attgggcatc gggtacgaac ctggcagctc aggagtcggg    480
gctccactca ccccacacaa aaagatgaaa aagcgcaaag agctcaatgc attgattggt    540
ttggctgggg acagccggag aaagaagccc aagaaaggcc caagcagtca ccgcctgctt    600
cgcactgagc ctcccgactc agactctgag tccagctccg aagaggaaga ggaattcggt    660
gtggttggaa atcgctctcg ctttgccaag ggagactatt tacgatgctg caagatctgt    720
tatccgctct gtggttttgt catccttgct gcctgtgttg tggcctgtgt tggcttggtg    780
tggatgcagg ttgctctcaa ggaggatctg gatgccctca aggaaaaatt tcgaacaatg    840
gaatctaatc agaaaagctc attccaagaa atccccaaac ttaatgaaga actactcagc    900
aagcaaaaac aacttgagaa gattgaatct ggagagatgg gtttgaacaa agtctggata    960
aacatcacag aaatgaataa gcagatttct ctgttgactt ctgcagtgaa ccacctcaaa   1020
gccaatgtta agtcagctgc agacttgatt agcctgccta ccactgtaga gggacttcag   1080
aagagtgtag cttccattgg cmatacttta aacagcgtcc atcttgctgt ggaagcacta   1140
cagaaaactg tggatgaaca caagaaaacg atggaattac tgcagagtga tatgaatcag   1200
cacttcttga aggagactcc tggaagcaac cagatcattc cgtcaccttc agccacatca   1260
gaacttgaca ataaaaccca cagtgagaat ttgaaacaga tgggtgatag atctgccact   1320
ctgaaaagac agtctttgga tcaagtcacc aacagaacag atacagtaaa aatccaaagc   1380
ataaagaaag aagatagttc caaattctcc aggtatccca agcttaagag agraactcca   1440
gcttgatcca gtgctcttac aaacaaacct grgagcaaca ggcctccaga gaccgccgat   1500
gaagagcaag tagagagttt cacatcaaag ccatcagcat tgccaaaatt ttcacagttt   1560
cttggagacc cagttgagaa agctgcccaa ctaagaccta tctccctacc aggagtttct   1620
agcactgaag atcttcagga tttattccgc aagactggcc aggacgtgga tgggaagctg   1680
acctaccagg aaatctggac ctccctaggt tctgctatgc cagaaccaga gagcttgaga   1740
gcatttgatt ccgatggaga tggaagatac tcattcctgg agctaagggt agctttaggt   1800
atctagcttc atcaggcata ttttagaaat ggactgccta atatctattt acctaacaac   1860
aaaacaaccc ttacttaccc atcagtcctc tagtcctcca aactactgta gcagatactt   1920
tgccaccttt taacttgttt gaagaagcta tataaaagtt atttttttaa agaagaagac   1980
cattttactt atgatgttca gaaatctatg atttcctaca accagtaaga tcttacattt   2040
taaaattgcc agaaaaaaaa ttaaagccct ctttttttct ctttcctttt tttgagggga   2100
ggagacctta tcttttaaag ctgggaaatg tatatagaga gagaataagc cacttttata   2160
tttcacttaa atttgcctta aattagctgc actttataga gactcagaaa atgtcttttc   2220
tttaaaagat aggccttttc tgtttgtaaa tatttaaatg aaagaaagca ttgtgcatat   2280
tgtgtggaaa gtaggaagaa tggttttgaa caggatatga acaaatgact tattaaaaat   2340
tgctgatctg gtgtaggtgg cagctgaaac tacatccatg tctccataag gyatccctca   2400
aaggcccagg cgctgccagg gggtttgtcc tggtagctgg aggaaccgat ttcagggagt   2460
agacactgga gacaatactg actccaggca tggctcatgg aagtaggatt ctggttcttt   2520
gttcctattc cctcagctaa tcccaacctg ggaatcagag aagtcttggg gatttttctc   2580
atttttagta ctatttcagg gtttatgagc ataaaaagtt atccattggg gagctccatt   2640
ttccctgctg agtgagctag attgccttcc ccacccaccc acttaagtct gtcttaaagc   2700
cgtagctggc tcccaccacc agtaccatct ccatttgaat ggcagggcta aattccccca   2760
gccattatct cacactgacc acccagagct ttagaagaga gctgtgcttc taattttgac   2820
ccagaaaacc ataccccttg agattttacc tagaggctaa ccaagagcct aatatgtttc   2880
tctgggggat gactaaagcc aaaaaggctg tgagatgaaa catgtgaaat aatattcagt   2940
ttccttacca ttaccagctc agaagtagct agaggctttc tacccaaagg atgccaaagt   3000
atagcagggc aggcctggag ctagggcctt cacatggtgg tagcaagttt ttcaaatcta   3060
atacaatcaa gtacaatact tcctttaaat gcttctgtgg acctggcatg aaagatccct   3120
agattgaaag gaataatacc tccatgtctc ctgtatgttg agtctagaat tgctgtgttg   3180
ttcttagaag cagtctttgg gcaacaactt gaaaggggaa aaaaaaacta caaaaactta   3240
actttggtat aggccaagtc agggagaaag tagagaaagc tgtcatgcca cagacttctt   3300
tagtggagat catttccttt ttaactttgt tcaggttgcc cttcaccatg gatacagtcc   3360
ggtaccctta aacatttaag ggctgttttt tttttcttta catgatgttc agcttggtat   3420
taaccaaact taaatttttt ttccagaagt attaaaattt agttaaagca agatgaagtc   3480
ttttcccatg aatgtgtccc cttatctcat tatagcttat gctcagtttc actttcttgg   3540
aaaggttaaa acaaattagc ctggcacttt aggtaacttg aaaataactc tcacccttct   3600
gactgccttc catccactct caccccacac ctttttttaa tatatataca cccttacaga   3660
ttttctaaca accaaataaa attctagcaa taaattgaat tatactgcta tatttgtata   3720
tactgtacca taaatagtat gtctgtacct ggaaggtatt tttttgagaa ctgatttata   3780
tgaaatatac ttgagggtaa tgtagcttgt cctttttagt ttcaaattct tattcatagg   3840
cagatacttt gaagacacct taactctttg ttgtgtgtat tttcccttgc atcagataac   3900
tatacatgga gaaatccatt ttgttttttg gtttatcttc tgttcttcct accttgtgct   3960
tgtctgacta gtatcacccc tgagccagta tacagtacca tcctctcccc ctaccaagtt   4020
tggcagaggt gtttatactg cattctcaga tctatgaata tttttgtcat cctgcctgag   4080
aaagtacatc ttccaggcaa aagtagggta tcttgaactc ctttcttctg agttgagcag   4140
actcactggc ttaagcatcc cataagccta ttatttagtg tgaatttggg acttttattt   4200
gtatgttgtc ttaacttact gagcctgtga cttgtattta gctgtagtca agcctcacca   4260
gccatatctc atctctgaga ggaagactgg atagtgagtt tggttttggt tttggtttta   4320
aaccctttta ccttttcagt ctggcagctc ctactgctgc tttcctaagt tactcaaagc   4380
actgcttctt ggtccttgtt ttcttttgcc ttgtactatc ttgtataatg tttactaaaa   4440
gagcctcccc ataaatcaga gaggcaaaaa ggtagcatat aaaaagaaga accaaaagaa   4500
gagaaaacct gacttctaga tgactgtggt gtcatctaaa aggcagaggt gcctgaccct   4560
caggaatgtg tatgatgcaa cagagctgaa gaatgggttc ccttcaccta ctgctggcca   4620
ttgtcccttc tgttggagat tcctttcttt atggttgctg ttcataaccc cttcaacacc   4680
cccccttgct ggtcctgccg gtcacagttg aggattttgg ctgtgatggg ctcatactca   4740
taatggcctg ttgagttgtt tttagtgaca ggttttgttt gctgcacacc tcattggctt   4800
gcttaccaac accagctaga agtggtccct ctttcatatc caaaccagaa cacatttggg   4860
tattcctgag actttataga gcgtgtattg tttgttatac gaacctaacc taccttgttg   4920
ttttctcata ttaagaaatt taaatctact ttgttttagt gaagctattt tggtaatgta   4980
taagcaattt tggttctgtt tagggagaat tcagggtttc catgacttga tttgagcttt   5040
gcatatttca aataagtaac acagccattt taatttagct aaataaaaaa atttcttttt   5100
tctcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                       5141

<210> 752
<211> 622
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (592)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (611)
<223> n equals a,t,g, or c

<400> 752
gagggctccg gccgcggagt gatggtggcc tcagcgaaga tgggccgggc agggaccatg     60
gcggtggcag cagaggtggc aggggcgggg cggctggcgg tagaggaggc tgtggtcctc    120
agggggctgt aggtggaggt atggctcggg ccagcagcgg gaacggcagc gaggaggcct    180
ggggggcact tcgggcgccg caacagcagc ttcgagagct gtgcccagga gtgaacaacc    240
agccctacct ctgtgagagt ggtcactgct gcggggagac tggctgctgc acctactact    300
atgagctctg gtggttctgg ctgctctgga ctgtcctcat cctctttagc tgctgttgcg    360
ccttccgcca ccgacgagct aaactcaggc tgcaacaaca gcagcggcag cgtgaaatca    420
acttgttggc ctatcatggg gcatgccatg gggctggtcc tttccctacc ggttcactgc    480
ttgaccttcg cttyctcagc accttcaaag cccccagcct acgargatgt ggktcamcgc    540
ccargcacac caaccccccc ttatamtgtg ggcccaggcg gccctttgat gntttcagtg    600
nacaaacctg ntggtccttc tt                                             622

<210> 753
<211> 3762
<212> DNA
<213> Homo sapiens

<400> 753
gccaccaagg agatttggag cccattttag aggcatctgt tctatcttcc catcataaaa     60
aagcggagtg cagtagcatg atctcggctc gctgcaacct ccgcctcctg ggttcaagcg    120
attctcctgc ctcgactaca gagctctgag gaacatgaat acagtgatga agctcctcag    180
gaagatgagg gctttatggg catgtcccct ctcttacaag cccatcatgc tatggaaaaa    240
atggaagaat ttgtttgtaa ggtatgggaa ggtcggtggc gagtgatccc tcatgatgta    300
ctaccagact ggctcaagga taatgacttc ctcttgcatg gacaccggcc tcctatgcct    360
tctttccggg cctgttttaa gagcattttc agaatacaca cagaaacagg caacatttgg    420
acacatctct taggttgtgt attcttcctg tgcctgggga tcttttatat gtttcgccca    480
aatatctcct tygtggcccc tctgcaagag aaggtggtct ttggattatt tttcttagga    540
gccattctct gcctttcttt ttcatggctc ttycacacag tctactgcca ctcaragggg    600
gtctctcggc tcttctctaa actgggatta ctctggtatt gctcttctga attatgggaa    660
gttttgttcc tkggytttat tawtctttct actgtaatcc acaacctgst tcatctactg    720
attgtcatct gtgtgctggg gcattgcagc cattatagtc tcccagtggg acatgtttgc    780
cacccctcag tatcggggag taagagcagg agtgtttttg ggcctaggcc tgagtggaat    840
cattcctacc ttgcactatg tcatctcgga ggggttcctt aaggccgcca ccatagkgca    900
gataggctgg ttgatgctga tggccagcct ctacatcaca ggagctgccc tgtatgctgc    960
ccggatcccc gaacgctttt tccctggcaa atgtgacatc tggtttcact ctcatcagct   1020
gtttcatatc tttgtggttg ctggagcttt tgttcacttc catggtgtct caaacctcca   1080
ggagtttcgt ttcatgatcg gcgggggctg cagtgaagag gatgcactgt gatacctacc   1140
agtctccagg gactatgacc ctaaaccagg gcstgcggca cttgcgggcc tccctgctgg   1200
ctactgatgc cagtaccaga ggagccccaa aactttgaca gcctcgtggg ctttgtgacg   1260
gcccaggggc tctgcgtggt acatgactga gaagagaaaa acaaaaataa atcatacctc   1320
aaaggatgga gtgcatcaat tgggagaaaa ggagacatag cccaaaccct ggcttattct   1380
tgggatctac tgattgcggg ctctgcaaga cccttggcaa actggcttct gatccatatc   1440
atatttattt gtagaagatg gcgaaacagt ttagctggtg gttctttctt ctccctttct   1500
ctctctctat gacaataata caaaccaatt taagtgaaca tttatatccg ataaggggtg   1560
ggagtgtgat tttaaatgct cttttgggag aacaaagaaa ttaatgtaaa taagatttct   1620
aactgtttaa ataagacttt atataaatgt ttaaaacata ggggtaaggg agggagggag   1680
aatttttgta tagaatgaaa catgcaagta ccacacactg tttgaatttt gcacaaaaag   1740
tgactgtagg atcaggtgat agccccggaa tgtacagtgt cttggtgcac caagatgcct   1800
tctaaaggct gacatacctt ggaccctaat ggggcagaga gtatagccct agcccagtgg   1860
tgacatgacc actccctttg ggaggcctga ggtagagggg agtggtatgt gttttctcag   1920
tggaagcagc acatgagtgg gtgacaggat gttagataaa ggctctagtt agggtgtcat   1980
tgtcatttga gagactgaca cactcctagc agctggtaaa ggggtgctgg aggccatgga   2040
ggagctctag aaacattagc atgggctgat ctgattactt cctggcatcc cgctcacttt   2100
tatgggaagt cttattagag ggatgggaca gttttccata tccttgctgt ggagctctgg   2160
aacactctct aaatttccct ctattaaaaa tcactgccct aactacactt cctccttgag   2220
ggaatagaaa tggacctttc tctgacatag ttcttggcat gggagccagc cacaaatgag   2280
attctgacgt gtccaggttt ctcctgagct catctacata gattggtaga cccttccttt   2340
ggattaggaa agatgagttt tacctctggt acactgtctt ggtaagcctg gatgtgacag   2400
acacctcggc tctccttgaa taagaaagcc agcagaactc ttaaagccag ttgtagtacg   2460
gagttgtcag cactcactga acctcacttt acagggataa gagtggtgtg gcattttaaa   2520
tacaatggta tgttattgcc agggagtgag gtacaagacg atggctcatg tcacaggcct   2580
acctgatacg gtgtcagaga aagtggtggg gaaaggatct ggttcatgga attctgatct   2640
tggcccatag gtgaaccacc aaaatagtgc tcgagtctta ggttactgtc atcaaagact   2700
tgggatgact ccattatatc ctggggttgt gggtattaga actaaatatg gaggtcctga   2760
gcatggggac tggcgtcctc agtaggtgtt tgggaatatg ggaagggtct cctatttatt   2820
caatagagtt ttctcagtta ttttcctccc ttgcccttgc aatctccagc aaaaggtggg   2880
atctaggaag aaagaatcca gtgtagaagt tgagaagaac ttgaacgttt tggttctgga   2940
taaggtcact gtcctaggtg ctaggtggac cgagcaaaag actcagtgga tgaactggtg   3000
cagtgcctga cagaataaag aacagtatta atccctttga gaaagcatag tccagcagga   3060
cagtggccat ttggacagaa gcccacttag tttcttggga gcaacagcac gtatcagaag   3120
ccagacttgc tcttcggtca tgcactttgg gatacagcgt ataggtgcag ccctgtcaca   3180
acaccaacag aagtagcagc ctctgggtgc agtcacccac accccaaagc tggaaggatc   3240
tggttcaaca tagcacaaac ccttaggaaa aatgaaatta acatcactga tgtgtaatcc   3300
agtaaaatct ccctttttcg ggtgtgtatg tgggcatgtg cccatttcta tgtgtgtgtc   3360
tacgtgcagc tcactaccaa cagcctcatg tgcacttgac ctgacagtgc tcgctgagaa   3420
ctctcaccag gttggcgcct gaatgcctta ctctcagcag tcagaggctt gcttgctctg   3480
tgcagatttt taattttctt ttttggccct aggctggttg ggacctctac agcttcattc   3540
tttcaccatt aaatagtggc ctttttcagt attttccctc ttccccttta taaattatgc   3600
taaagccaca aagcacattt ttggggatca tagaaggttg gggttccaga aaggcatctg   3660
tgtgatggtt ccattgatgt gggatttccc tacttgctgt attctcagtt tctaataaaa   3720
agaaccaaat gaaatatgaa aaaaaaaaaa aaaagggcgg cc                      3762

<210> 754
<211> 2455
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2417)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2443)
<223> n equals a,t,g, or c

<400> 754
gaggaatgat ttttgtctgc tctgcaaccc ataaaaccaa atcgatgttc ttctttttgg     60
ctcaaactga gcagggagat atctttaaga tcactttgga gacagatgaa gatatggtta    120
ctgagatccg gctcaaatat tttgatactg tacccgttgc tgctgccatg tgtgtgctta    180
aaacagggtt sctttttgta gcatcagaat ttggaaacca ttacttatat caaattgcac    240
atcttggagr tgatgatgaa gaacctgagt tttcatcagc catgcctctg gaagaaggag    300
acacattctt ttttcagcca agaccactta aaaaccttgt gctggttgat gagttggaca    360
gcctctctcc cattctgttt tgccagatag ctgatctggc caatgaagat actccacagt    420
tgtatgtggc ctgtggtagg ggaccccgat catctytgag agtcctaaga catggacttg    480
aggtgtcaga aatggctgtt tctgagctac ctggtaaccc caacgctgtc tggacagtgc    540
gtcgacacat tgaagatgag tttgatgcct acatcattgt gtctttcgtg aatgccaccc    600
tagtgttgtc cattggagaa actgtagaag aagtgactga ctctgggttc ctggggacca    660
ccccgacctt gtcctgctcc ttattaggag atgatgcctt ggtgcaggtc tatccagatg    720
gcattcggca catacgagca gacaagagag tcaatgagtg gaagacccct ggaaagaaaa    780
caattgtgaa gtgtgcagtg aaccagcgac aagtggtgat tgccctgaca ggaggagagc    840
tggtctattt cgagatggat ccttcaggac agctgaatga gtacacagaa cggaaggaga    900
tgtcagcaga tgtggtgtgc atgagtctgg ccaatgtacc ccctggagag cagcggtctc    960
gcttcctggc tgtggggctt gtggacaaca ctgtcagaat catctccctg gatccctcag   1020
actgtttgca acctctaagc atgcaggctc tcccagccca gcctgagtcc ttgtgtatcg   1080
tggaaatggg tgggactgag aagcaggatg agctgggtga gaggggctcg attggcttcc   1140
tatacctgaa tattgggcta cagaacggtg tgctgctgag gactgtcttg gaccctgtca   1200
ctggggattt gtctgatact cgcactcggt acctggggtc ccgtcctgtg aagctcttcc   1260
gagtccgaat gcaaggccag gaggcagtat tggccatgtc aagccgctca tggttgagct   1320
attcttacca atctcgcttc catctcaccc cactgtctta cgagacactg gaatttgcat   1380
cgggttttgc ctcggaacag tgtcccgagg gcattgtggc catctccacc aacaccctac   1440
ggattttggc attagagaag ctcggtgctg tcttcaatca agtagccttc ccactgcagt   1500
acacacccag gaaatttgtc atccaccctg agagtaacaa ccttattatc attgaaacgg   1560
accacaatgc ctacactgag gccacgaaag ctcagagaaa gcagcagatg gcagaggaaa   1620
tggtggaagc agcaggggag gatgagcggg agctggccgc agagatggca gcagcattcc   1680
tcaatgaaaa cctccctgaa tccatctttg gagctcccaa ggctggcaat gggcagtggg   1740
cctctgtgat ccgagtgatg aatcccattc aagggaacac actggacctt gtccagctgg   1800
aacagaatga ggcagctttt agtgtggctg tgtgcaggtt ttccaacact ggtgaagact   1860
ggtatgtgct ggtgggtgtg gccaaggacc tgatactaaa cccccgatct gtggcagggg   1920
gcttcgtcta tacttacaag cttgtgaaca atggggaaaa actggagttt ttgcacaaga   1980
ctcctgtgga agaggtccct gctgctattg ccccattcca ggggagggtg ttgattggtg   2040
tggggaagct gttgcgtgtc tatgacctgg gaaagaagaa gttactccga aaatgtgaga   2100
ataagcatat tgccaattat atctctggga tccagactat yggacatagg gtaattgtat   2160
ctgatgtcca agaaagtttc atctgggttc gctacaagcg taatgaaaac cagcttatca   2220
tctttgctga tgatacctac ccccgatggg tcactacagc cagcctcctg gactatgaca   2280
ctgtggctgg ggcagacaag tttggcaaca tatgtgtggt gaggctccca cctaacacca   2340
atgatgaagt agatgaggat cctacaggaa acaaagccct gtgggaccgt ggcttgctca   2400
atggggcctc ccagaanggc aagnaaaggg ggggttttgg ggnaaaaaaa ttttt        2455

<210> 755
<211> 650
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (352)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (581)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<400> 755
ggcagagccc acattctact ggaatgacct gctgcacttc tgtgagcttc aaatctgaga     60
tgtgctttca tcctcccgtg tgtggcaggg cgccttgtta gtgtccaggc ctcttggaat    120
gtggtttggt tcaggggtac tgatggcccg agtgcttgcc cacggcagag gaggccaggg    180
gtcagtacag gagccagtcc tcgccaccct gttcctgacc atacagagtc tgtcacctgc    240
ctgtgccctg attgtacccc atctgcaccg tgtctgcacc ctgcctgcgc cctgtctgta    300
ccccatgtgc gccccatccg taccctgcct gcgccatctg cgccctctyc gnaccctgtc    360
tgtgtcgtct gtgccctgtc tgtgccccgt ccgcatcccg ctgcgccctg tctgtgcccc    420
gtccgcaccc tgctgsaccc catccatatc ctgstctgct gctgcaccct ctctgcaccc    480
tgtctgcgcc gtcgtgcccg tctgcacctt gctgtgcccg tcacaccctg cctgcactct    540
gctgtgccca tctgggcctc tgacgcccta ctgtgccctg nctgtctaat agatctgcag    600
cgctccgctn tgtarcagcc ccgaccctaa ggatgcttca tgaatagaca               650

<210> 756
<211> 1581
<212> DNA
<213> Homo sapiens

<400> 756
ggcgcactgt caccgagggc acataaatgt atgctcagcc ctcgtgatgg cagtgggcca     60
gaacaggccg ctgttcccat ggtattatgg gcatcttaca tgcagcatat ttgttaggct    120
gtgttagccc gattctgccc tccacccccg tcaaccctag agtttaccca ggaccaaaag    180
taaacttaaa tatcctctgt gtcatggcct cggcttacct aacatgttct acagatagat    240
gttgttcaac aacagtaatg atacccttca aagaagcttt tgaaaagcca acgtgaattt    300
ccaaaagcca acactagagc tgatgtgtgc cctgcttgcc tttattttca aggtgttctg    360
aagacgcaga tcccgatatt aacttaccaa ggtggatcag tggaagctgc tcaggcattc    420
ctgtgcaaaa atggggaccc gcagacacct agatttgacc acctggtggc catagagcgt    480
gccggaagag ctgctgatgg caattactac aatgcaagga agatgaacat caagcacttg    540
gttgacccca ttgacgatct ttttcttgct gcgaagaaga ttcctggaat ctcatcaact    600
ggagtcggtg atggaggcaa cgagcttggg atgggtaaag tcaaggaggc tgtgaggagg    660
cacatacggc acgggratgt catcgcctgc gacgtggagg ctgactttgc cgtcattgct    720
ggtgtttcta actggggagg ctatgccctg gcctgcgcac tctacatcct gtactcatgt    780
gctgtccaca gtcagtacct gaggaaagca gtcggaccct ccagggcacc tggagatcag    840
gcctggactc aggccctccc gtcggtcatt aaggaagaaa aaatgctggg catcttggtg    900
cagcacaaag tccggagtgg cgtctcgggc atcgtgggca tggaggtgga tgggctgccc    960
ttccacaaca cccacgccga gatgatccag aagctggtgg acgtcaccac ggcacaggtg   1020
taaccgtcca tgttccgtgt gagcagagtc cctaccaacg ggcaggtctg catccgggga   1080
gaatgcagct gcttctggcg acaatcctgc tagtaaacac tggtcttcgg tgagcaacga   1140
acactcgcct ggcctgggaa actgcatgcc cactttctgg gaggggttag tgcaggtgcc   1200
gtggacaaag gacaacattt ctctggggct ttttaacttt tattcctaag actctaaagg   1260
cgttgatttc aaccctcctt cactctggct tcttcaggca acccacgtgg tctcctgtga   1320
gaatcttctc gacagttact tatggggaca cttgtgaaca attaactgcc aggcagagca   1380
tgagaacaaa cattcccagg ccatgtagga taggatactc cagactccag tcatcctccc   1440
ccatccatgg tttctgttac tcatggtttc agttactcat agccaactgc agaccgaaaa   1500
tactaaatga aaaatttcag aaataaacaa ctcttaagtt ttaaaaaaaa aaaaaaaaaa   1560
aaaaaaaaaa agggcggccg c                                             1581

<210> 757
<211> 1714
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1691)
<223> n equals a,t,g, or c

<400> 757
tcgacccacg cgtccgccca cgcgtccgcc ccgtgcacgg gagccagctc cgcagatggg     60
cgcgcctggc tgagcttgcc gccctgtagg cttggcgctg ggctctcggt ttgttcttca    120
tttttaaaga aggaagggtc atatgtttat tgctaaactg tcaaaaagga atatattctg    180
attaaattat tactcctcac tttgagggtg tgagaatttt agaagattta aatgttctat    240
ataacactta gatttctgat attttggaag aagttagaag ttaatgaaag caaactcagt    300
taccaatttt ctggaaaata tccatgtggt aatggtagac tttttaggtg gcaatttcta    360
ggtctgaaat atagcagagg aaagggcgct gaggcagttg caggcaggca gccctgtact    420
taccctgtac tcacctcatc cgacagacgc tgtggatgag gaggggcttg gcggaggcgt    480
gagcaccgat gtccctttga taacctgcac tcaccaagat gaactatttg ccgccctgtc    540
ttttcctggg ttggggggtg gcatctgatg gtggcagagt gcctgttggt tcgcccgtgg    600
gtctcatggt tcagacagag ggaggtggac ggcagggatc agggagccag gagcgcgcct    660
cagacttgca gcaaccattg tgatttgggt tgttcggaat atttaaatta ctgatcagaa    720
gatgaaagta gcttttctct tgggaagtct tgcagcccgt gggagtgata ccaggagcaa    780
cacagagctc agcagcggcg ccaaggtgtt ccctgtttcc tcagcacgtg agccttcacc    840
gcctgcttca ttcaggagcc agtgcagcag taatacagtc tatacattgt tctgttttca    900
aatttatcct gaggctttgt tgagcataaa tgattatacg ataaaggtat ccgttatttt    960
ggaactcatt tcagttggga tctcctgtat gcagagtgtt gcatttagag gtttgagtcc   1020
catcttggtt tcttgccgtg ctgactgtag ccttcacctt gacttgaatg aaggtctgtg   1080
gttggaatgt gtgaggagcc gctgaggtgt tcaggaggtg ctgcctggag gtcggtttct   1140
tcctgggtgt tacgggcaac tgctcacaca gttgtttctc tgtgaacatt tccagtgttt   1200
aatccaaaat gaaaacccac caatgctttt gctaacttca gtgcctttta taaatcattt   1260
ttaaatttcc tgaacttgct ttttgaggat atacagggat attaagtaga cgcaggattg   1320
tttttgtttg taaaaattct gaattgaaac tttgttttaa aaaaaggctt ctttctttca   1380
tatgacaaga gataggtcag gaatattgga atcaagattt aaatgttaaa attcgatttt   1440
gttacacagg gtgtgttcat ttgttttgta gcagacaaga tctagatccc agacagaaac   1500
aacacatgct attctaaaaa gccgcatttt aaaaggcacc ttggttctca aaagaaatca   1560
gaatatggat attcgtagtg atgatctgtt ttctctaaaa tcttaccata ttgtctgtat   1620
atggttgtaa attcaaatgg aaagtaaaac gttttggccc tgaaaaaaaa aaaaaaaaaa   1680
aaaaaaaaat nactgcggtc cgtcaaggga attc                               1714

<210> 758
<211> 408
<212> DNA
<213> Homo sapiens

<400> 758
ggaagcttgg ctgaaaccat ctgccttgtg acagggacac acaagatgct cagcgcattc     60
aatgcaacgt cagggaaagc catttggact ttaaacccaa actacttgtc caacggtacc    120
ttggctgccc cagttgtggt actgccagac ttggatgaag acggtgttcg agaccttgtg    180
gttctggcca ttggggaatt gcagccagat ctgtgctttc tgctggtgtc tggccggacc    240
ggaaatccag tgggtcgacc tgtgaagtac aacatcgttg ggagttggga atctgaattg    300
gtcctcaggt ttacatcacc acaaatgggg ctgtctacat cctgtttggg tttggaaata    360
tacaagctgt cgcactgcgg ggacattttt gttccagggc caaaatcg                 408

<210> 759
<211> 1914
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (384)
<223> n equals a,t,g, or c

<400> 759
agactgttct gtgtcctgtg gtgggtttaa cagcagcact cactctgcct gctagatgcc     60
agtagcaacc tccttcataa gctgtgatag ccagaaatat ccccagacat tgtcaaatgt    120
ctcctggggg taaaattgcc tctggttgag aaccactggt atattgtcta tgtctccagt    180
tagaagggca gttccatgag agtgaagacc ccacgtccaa gttcctcagg gccctgatga    240
cctcagcctg gcattcactc ttccatgcag ctgatcctcc ccaaagccct ggactgggcg    300
caggctacct gagaagcaca tcaaagcgtt tgttctacag gaccctcgtc tgtgggcttg    360
tgcagcttgg ggccagggat ggtngcctac tggcctttgc actgccagta cccacccagg    420
ctttgctttc agggtggtca gaaaatgatt actgggggaa cacatgacag aaaagcagga    480
agggggcctc ttggtgctgt gagctgacca gtgcacagtg ttggtccttc tcgacaggga    540
tgacttctac tttttggaag ggagagttca gactttatta gataccttaa ggctggccct    600
ggggaaaacc gtggctggct tcaccatcct cctaatagga agaggcagtg aggagaacag    660
tagtctgggg aaggtgggag ccccaactga ggggcctgca cccagcccct cagatccgcc    720
tcccctccca tgtcactcca gctcttttgg gatgatcaca tggtgagaat ctgctttgaa    780
gatatgaagg gcttcatgga ggcttccaag gcagactggt agtcctgcag cgggacctgg    840
gagcaggcag gggctgtgag ctggcctcgg cggatgagat cgcacagtgt gaggatcagc    900
tccttgaact ggtctggact gtgatccttc ttccactggg acaaccaaaa gcctcgaagt    960
ttgagatcct taaaaatgag caggctcaca gaggctacga cgggctgctt ggccatcccc   1020
ccataggtta ccatggttcc tccasgcgct aactgccgca gcagctctgt ggagcttttc   1080
ccaccaacac agttgagagc aagccgtggc tggggcatgt ccttaaagaa gtttttcatt   1140
tcgggccttc ttagctcctc ttctgtgatg acatgctcag cccccagact cttcagtctg   1200
tcactcagct tctggatatc aggtctgtct cggaccacat tgatggttct taggcccagg   1260
gctgcggcga tctggatgac cgcttgcccc actccgctgt tggatgcatt ctggatgaca   1320
gaatcccctg gctgcagttg ctcgaagtcc atcaacatcc tgtaggctgt gcagggattg   1380
acacccaggg tggcagcgct ctgaagaggg atgtcactcg gaacttggat cagtgcttcc   1440
tcgctgaaca cagcctcggt ccgccaggtt cctaaaccag catttgctgg aatcacccag   1500
tctcctggct tcagcccggt cacattgctg cccaccgcta ccacctgtgc aacaccttcg   1560
ttccctccaa cagcaggcag ttcaggaagg artccgtagt ttccttggat catatttatg   1620
tcagatggat tgataggggc cgccagcatc ttcacacgga catctgatcc tctcacagca   1680
gctagctcca ggttcttgag ttcgacgacc ttggctggat ccccgtggtg cccatagaca   1740
agcgcccgga cccgggcagg ctcggcggat gcggagtagg aggaggcggc aggtccgtga   1800
cagccagaag ctgggagcag cccccgccac tgccgggcgg gggttcgcac ccgccacagg   1860
gtactgcaga cccacatgct cgctccaacc aacacagagc ctgacgctcg tgcc         1914

<210> 760
<211> 2631
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2619)
<223> n equals a,t,g, or c

<400> 760
ggcagagcca cagtgataga atacgtgaag ccctcagacc tcaaaaagga catgaacgag     60
accttcaggg agaagttccc ccatgtcaaa ctgacgctga gcaaaatcag gagcttaaag    120
cgkgagatgc ggagcctgtc ggaggagtgc agcctggagc ccgtgacggt ggccatggcc    180
tacgtgtact ttgagaagct ggtcctgcag ggcaagctca gcaaacagaa ccgcaagctg    240
tgcgctggcg cctgcgtgct gctggctgcc aagatcagca gtgacctgcg caagagcggc    300
gtgaagcagc tcatcgataa gttagaagaa aggtttcgat tcaacaggcg cgacctgata    360
gggtttgagt tcacagtgct cgtggccttg gagctggccc tgtatcttcc cgagaaccaa    420
gtgttacctc attacaggcg cctcacccag cagttctagc agaggcccca cagaaggctc    480
agggcaccga ggtgcacttg ccggcctggg aggtgtccca ctgaagcccc gcgcctcctc    540
ctgccagcac ccccagcacc tgctagcagg aggcacctgg cctccgctgg tgcagctttc    600
ctttttgcct ctttgccatt tccttggaaa gagacgtcgc tttcatcccc aagtgcaccg    660
tccctccgag gggatttctg agaattctcc tgcattttta cataaactaa atgtgaggtt    720
tgttactggt atttttttca cgtgcctgag accagcctgg taccaggacc ttttgttcac    780
agcgtgcagc agcgagccgg ctgcagtgyg tctcccctgg cctcgccttc tgcaaaccac    840
cgcagccacc acagcgtcag ggtggagatc tgggtttcta gacctcactg aacacactga    900
aatggctgag tttaacttat ttaggcattc atcttggaga tgtggttttt cgggttcccc    960
agcagcatct cccgacacca actgtgccgc tggctccctg ccacctgaag ccgagctcct   1020
ccagagcttt ctccgcccac ctcactgcat cccaagtgga gcttttggtg tccagttagg   1080
ccagcgggag cagtctcctg atttattttg atctcattct tggactcttg gacctctctg   1140
ttcttcaagc atcgtgtcac tgtgaaatcc taacgcccct gtgtcctaca gaccgacggc   1200
acaacagaca gctgcccatc ccatgccatg ctctaccctc tgcctctcac caggagacac   1260
tctgggcctc caggacaatt gctgcttgcc ggctcttatt tttctaagca atattgtgat   1320
ggagaaaaat aacatattta ttgggatttg gttttttggg tctttttttt ttaagggaac   1380
aaaaaatggt taaatgaggt ctgctgaagt tgacttgaaa acacactkga ccctcaggca   1440
ggagggcact gaccacaccc cacacaacct caaagggtca gtgcgtcagt gccttttctt   1500
ctgaggcagg aaacaggtgc catcttggcc acctcggcca gggcagccca ccatgctaaa   1560
aggaccccaa atggtggtcg ttgtcccttc tgtgcaggcc agcagggccc catctctagt   1620
ttttccacgt ctgtctgaag ttcttgcaac aaattctgca tggtccagcg ctccagctag   1680
ctgcctcatc aaaaacactg aataaccaag gactgctgag tttttcttca tggggggtca   1740
gctggtctca aaactggcca ctgcctcagc caccaagctt tttcctacca ctaccttata   1800
aacctgcctg gccctggagg ggctctggga cgactttgtc tctagcccat taatacaata   1860
catcctatgc tttctgtgca gactggtgct tccgcagaaa ggagatgcca attctgctat   1920
cacagaactc caccagcaac tccacccgac cccagcagtg gtgcaggaca gctgccagca   1980
cccacctggc cctcctcctt ttccacagcc actcactggg gccaccaaaa cccagagatg   2040
gcaggtgtgt gggacagact ggaggatgag gacaaaccaa agcctttgtt ctttcttatt   2100
gtggagcgtc cccttccatc aagcagcctg ccctcaagcc aaggatcatc ccctggaacc   2160
cagtatgcac ccagagggga ctcarcttca aagctgctcc accatgctgg gtcccaggca   2220
gctttcctct gaaaagcaac ctctcctgcc acccagatcc catctcaaga gctcgcccat   2280
gttacgagca tgtaaaggac tgacttccta gtaactgttg cagtttacaa cctgccctcc   2340
agggacacgt ctccatggtt tttyctacac atgaatgcga gaaatggctg ataagcacag   2400
taatttaaga ttgcgtattc atgtagtgag atttagtcat taaccaaccc ggtctttgtg   2460
atgtgtgaag ccttcccttc agttatgtcc catttttatg atgccaaaag ctgccactgt   2520
gtggtattcg aggattattg caacaaagcc agtagttaaa ccaaaaaaaa aaaaaaaaaa   2580
ctcgaggggg ggcccggtac ccaattcgcc agagagtgnc aatggcatca a            2631

<210> 761
<211> 2263
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (589)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2141)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2146)
<223> n equals a,t,g, or c

<400> 761
aaccacttta aggaaactag aacagnattc aagaacaccc atcacagtgc ttaacaagat     60
ttaatgtaca tttattctta acatgtggaa catataaaga ttttatactg aataaatgat    120
attcattaag ccagaggaaa aggaggaatt tacatcaagt ttttttcttt tttttttttt    180
taaactacat tatcttgaaa tacaaatgtg gattctcatc actgaaaaat ctttgaagtt    240
gtgtttcttc cttttagttg tatttttttc attttctctt ttttgactgt actggtaacc    300
attttctaaa tcaatccata tataaccatt tccacacctt gattcatgaa gcaaattgtg    360
atcagctgct ctcctgaaat cgagcatgac tttatacata cagaaacttg tacattaccc    420
tctttttttt ttgtttttgt tttttgtatt ttttctttct ttttttggag atatggccct    480
aatgaaaaaa tatataaaat aaaaataaaa aattatttaa atctaccatc acttcgtagt    540
taccacatca tgaaaaagaa actaaaactt tgtactaaaa aaaaaaaana aaaagaaaag    600
aaaaaaatga gggtatgttt aatgtacaac ttctatatac atcacagccc ataggcagta    660
aaaaaaatat ttaaaaaatg atgaaaggaa ttgtgaagaa ctgtcacgtg gaaggtcaaa    720
cgccgacagc aggcatgacg ggagtggtga ggagcagttt ccggatcgtt gtcaggtatg    780
tattctcaat cttaaaaaac attgtttttg ctcccagcct aatggaacca tattcctgtg    840
gagaaaccag tatcatttca tagttttgac tactgaccga catacctcct tgagccccta    900
tacctgtatc tgtagaaatt tctattgcac agaactttgg gtgatgggat gcagtttttt    960
tcattctctg aggagtaaaa cgcataggaa atggataatt tttcaccttt ttgactcagt   1020
gtggtgaaat tttcgcatct tagcatcttt tgccacaact tttttcttta aagtcaattt   1080
gcttccccca aaaatgcaat acaacatggg aaagaacatt aaaaagatct gtgaagaaca   1140
aaaagtgacc tttgaatgca ctagacagca actttggtta aaaaaaagag aaaaaaaaaa   1200
ccccaaagga tgtacttata cacacagaca gcaaatatta atttcataac tgttcaaatt   1260
aattatttct ttaattccca attggtaaat agtgaatggg gcagaggagc aaagattttc   1320
ttttccttct tcctacgctg gataaacaag aacagaaaac agccagttat atgtgaccct   1380
ctaatcttca ctcacacatg cttgccttct cacttatgtc ataactgccc aatctgaaac   1440
agtacatcac agatgacaga tgcaaccaga gagttcagga cagctgatat cgagatatcc   1500
agcaaccggc cctcgtgcaa aaggaattcc gagcggtttt cgtccactct ggccatggct   1560
agcaaagcct tggccgccct gcacatcatg tctacgctag gtggttccag gggcgggggc   1620
tgcatgtgca tgaggttgtg ctggctctgc tggtactggg ccatcgtgac cccatcctct   1680
aggaagctta tcaagtttcc aatgcttcct ttctgcacag ctatggccct tgctgctagt   1740
gcgtcccctt gggcaaggtt cgataaaagc gccatggaca tttctcgaca gactgggttt   1800
ttgcgatccc caacgtacct aactaatgta gcatagaatt tctcctgacg actaaatgga   1860
ggagtggcca agatcaggtc cacattattg tcctggatac tgagtttaca gagggtctcc   1920
agcacaagtc tctgaggcga caggaccgag ttgggtccca cagttggaaa gggatcttgt   1980
gcctctgcag acgggcacac catccagtgc agcaagccat ccaaaattgg caagcagatg   2040
ctttccgtgt aagcagacaa gtctagctgc ccggaaatgt tggccaacgt gaccaacgtg   2100
ttatccctca agacctcgag gcagtcccac caccactcat ntttgntgca ggccaccccc   2160
ttgtcctcat cctcctcttt ctcataggtc tgcggtgctc gctttctctc tggatgctcg   2220
tggtgaagaa gaatcagctt ccccaggatc agcaccaggc ctg                     2263

<210> 762
<211> 791
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (668)
<223> n equals a,t,g, or c

<400> 762
ggcacgagtg gaactctcaa aggatccaat ccttcctgcc agacatcagg tctcttgtca     60
caatggatgc actccacttc cagtcatgaa ggccataagc agcacagatc acaaacttta    120
cctataattc gaggcaaaaa tgcactttct aaccccaaac tcttacagat gttagacaat    180
accatgacca gcaactccaa tgaaatagac atcgtgcatc atgtagacac tgaggccaat    240
atagctacgg aggtttgcct cactattctg gacctgttat ccctcttcac acagactcat    300
cagagacaac tccaacaatg tgactgtcaa aattcattga tgaaaagggt ctttgatacc    360
tacatgctct ttttccaagt caatcagtca gccacagcgc tgaagcatgt gtttgcctcc    420
ttgagactgt ttgtatgcaa gtttccttca gcgttctttc aagggcctgc tgacctctgt    480
ggatcattct gttacgagtc ctaaaatgct gtaaccacag gtcacggtca actcagacag    540
aagcctcagc ccttctgtac tttttcatga ggaagaattt tgaatttaac aagcagaagt    600
caattgtccg gtcccactta caagtaagtg ctgccaattt tcattaatgc tgttgttaaa    660
accactgnat ctgtttcagc agtgcttaaa gcctactgtc ctcaggcaag ccgtcactaa    720
ctccttccaa tagcgtcctc cttaaagacg cccacagcat tcagttcctg tttaataagt    780
aaggggcaca g                                                         791

<210> 763
<211> 1062
<212> DNA
<213> Homo sapiens

<400> 763
tgcagaagag ttcgaaagtg aggtagaatt cctttaagtg cagraagaag ccttcaagtt     60
gtccaatcag caagagtaag atgaccccat ctgcaaactg ggtgtccaga ttctgcacag    120
acaggcccag gcggtccagc ttctggttga caaagttcac gatggcctct ttcactgcgt    180
tcactttctc cggagccagc ttaaataatt catcaaagac gtcctttgga ggctcgtcct    240
tgtctgtgct gtattcagtg agctgttcca ccaacttctc tgacttcaga ccacttttgg    300
tgctctcgat agtgatgacc tccacctgra cgttggttgg gagggagagg tcgggctgga    360
agcgcttggc cagggccaca aggaggtgca gggtagacaa caggtccttg ttgaagatgc    420
tctccacgct ccacttggcc tgccactcct ccagctgcag actccggttc acggcctcca    480
gcaccactgt gagcttgtgc ttctggcttg tggctgtcag ggcgatgtcc tctgcttcca    540
gcttgagcgc cgccagcytc tggaataggt ggtgtaggat gagcccgtcg aacatgtcct    600
cytccaggct gcggaccaca atgtgctcgg ggagaagagt ggcattgatc cactccatca    660
acaccttctg cagttcttca aatttggggt ccttccggga agtgggtggc aggtatttct    720
tctttcctcc ttttgagagc tcctcctccg ctgggggctc cacccccttg gggagctgca    780
gcaggtcgta caagaactcc ggctccatcg cctcccaagc ccaaccgctt tccacgcagg    840
aaaacaaagg cctactgagt gcaaagggtg gtccctggat tccgaatgga agcaagttcc    900
gggttcttct ggggtcttcg gggaccaggc cgggaggcag gagccccgct gctcacttcc    960
tccaggcccg ctcagccggc aggagcttcc tcctctctgg actctcggct gcacgcggac   1020
cgcgtgggtc gacccggaat tccggacccg gtacctgcac gg                      1062

<210> 764
<211> 689
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (635)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (662)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (670)
<223> n equals a,t,g, or c

<400> 764
ggcacgagct cggacattga ggtggagaac cggcccctgc ctggccacac acagcttcga     60
ctgcctggct gccccacccc cgtgtctttt ggcctcctat tttctgttgc cttccccgtg    120
gatggagagc ctgcatctac acgggcgaca gttcgtcacc ccttgatggg gcagcctctt    180
cccctcatca cagactatgc tgttcagcca catgtgggca cgggggcagt gaaggtgact    240
ccagctcaca gtcctgccga tgctgagatg ggggcccgac atggcttgag ccccttgaat    300
gtcattgcgg argatgggaa tgacctctct ctgcggggac tggctgcagg gtcttcaccg    360
gtttgtggcc cgggaaaaga taatgtctgt gctgagtgaa yggggcctgt tccggggcct    420
ccagaaccac cccatggtac tgcccatctg cagccgttct ggggatgtga tagaatacct    480
gctgaagaac cagtggtttg tccgctgcca ggaaatgggg gcccgagctg ccaaggctgt    540
ggagtcgggg gccctggagc tcagtccctc cttccaccag aagaactggc agcactgggt    600
tttcccatat tggggactgg tgtgtctccc ggcanctgtg gttggggcca tcagattcca    660
gnctaacctn gttgttagag gaccatgtg                                      689

<210> 765
<211> 605
<212> DNA
<213> Homo sapiens

<400> 765
tcaattacta tttgactgac tgactgaatg aatgaatgaa tgaggaagaa aactgtgggt     60
aatcaaactg gcataaaatc cagtgcactc cctaggaaat ccgggaggta ttctggcttc    120
cctaagaaac aacggaagag aaggagcttg gatgaggaaa ctgttcagca agaggaaggg    180
cttctcacac tttcatgtgc ttgtggatca cctgaggatc ctgtgaaaat acagatactg    240
attcagtggg tctgtgtaga gcctgagact gccattctaa catgttccca ggggatgctg    300
atgctgctgg ccctgggact gcactgcatg catgtgaagc cctataggtc tcagcagagg    360
cccatggaga gggaatgtkt ggctctggct gcccagggcc caactcggtt cacacggatc    420
gtsctgctcc ctggccagcc tttggccaca gcaccaccag ctgctgttgc tgagagagct    480
tcttctctgt gaacatgttg gctttcatca gccamcctgg ggaagcggaa agtaagctgc    540
cactawcttt gtttccccac ctcargcctc amawtttccc atggaaaaag ggtgaatgta    600
tataa                                                                605

<210> 766
<211> 951
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (848)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (856)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (907)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (926)
<223> n equals a,t,g, or c

<400> 766
gaattcggca cgagctcgtg cgccagaaat tatagaagat ttggccttct actctagtac     60
agtagtatct ctattgatga cctgtgtaga aaaagcagga acagatgaga aaatgcttat    120
gaaggttttt cgctgtttgg gaagttggtt taacttggga gttttggaca gtaacttcat    180
ggctaacaat aaattactag cactcctttt tgaggttttg caacaggata agacctcgtc    240
taacctacat gaagctgctt cggactgtgt atgctcagct ctctatgcca ttgagaatgt    300
ggagactaac ttgccattag ccatgcaact ttttcaggga gtgctgacat tggagactgc    360
ctatcayatg gccgtggcac gtgaagattt agacaaagtt ctgaattact gccgtatttt    420
cactgaacta tgtgaaactt ttcttgaaaa aattgtttgt actccaggcc aaggtcttgg    480
ggaccttcga actctggagc tgctgcttat ctgtgcaggc catcctcaat atgaggtagt    540
gtttatgcta ttcaaaggcc attattctcc aagttgtgtg ctgcatatta tctatatttc    600
attacctcgt gcccaaattt ttattgttga gaaattacag tcttgttttt aattaatgtg    660
atttcatctg ttttggaatt tttaaaaaaa attatatttg ggtttctgca ttgtgtccat    720
ttctgttttc ttggcctccc aaagtgctga gattacaggc gtgagtcact gtgcccggsc    780
acctgcgtgt ttttgtatga aaaatkgaaa tgcaagcaaa aggactgggg tcaacctcca    840
cgtgtggntc tgggcnagcc atgaaaattc tccctaactc agtttcccca cccgtaaaat    900
ccatgangtc actactccta cttatnggtc aaaaatgcca aaaaccccca a             951

<210> 767
<211> 2385
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2362)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2364)
<223> n equals a,t,g, or c

<400> 767
atattatcct gtacatgcaa atcactgagg agcagattaa agtatggaca gccaaccccc     60
aacaatttgt agaagatgaa gatgatgata cattctccta tactgttaga atagcagctc    120
aagacttgtt gctggctgtg gcacagattt ccagaatgaa agtgcagcag ccctggctct    180
gcmgcsactc gacatttaca agaagctgag caaaccaaaa acagtggcac tgagcactgg    240
tggaagatcc atgaggcatg catgcttgcc ctaggctcag tgaaggccat catcactgac    300
agtgtgaaaa atggcaggat tcattttgac atgcatgggt tcctgaccaa tgtcatcctt    360
gcagacctca acctctcagt gtctcctttc ctcttgggcc gggcactttg ggctgccagt    420
cggttcactg ttgctatgtc ccctgaactg atccagcagt tcctacaggc aacagttagt    480
ggtcttcacg agacacagcc cccatcagtt cgaatttctg cagtgagagc catctggggt    540
tattgtgacc aactgaaagt ctcagagagt acccacgtgc tccagccctt cctccccagc    600
atccttgatg gcttaattca cctagcagcc cagttcagct cagaggtcct caacctggtg    660
atggagaccc tgtgcatcgt ttgtacagta gaccccgaat tcacagcaag catggaaagc    720
aaaatctgcc ccttcaccat cgccattttc ctaaagtaca gtaatgatcc cgtcgtcgcc    780
tcactggctc aggacatctt caaggagctg tcccagattg aagcctgtca gggcccaatg    840
caaatgaggc tgattcccac tctggtcagc ataatgcagg ccccagcaga caagattcct    900
gcagggcttt gtgcgacagc cattgatatc ctgacaacag tagtacgaaa tacaaagcct    960
cccctttccc agcttctcat ctgccaagct ttccctgctg tggcacagtg tacccttcac   1020
acagatgaca atgccaccat gcagaatggc ggagagtgct tgcgggccta tgtgtcagtg   1080
accctggaac aagtagccca gtggcatgat gagcagggcc acaatggact gtggtatgtg   1140
atgcaagtgg tgagccagct cctggacccc cgcacctcag agttcactgc ggcctttgtg   1200
ggccgccttg tttccaccct catctccaag gcagggcggg aactcgggga gaatctagac   1260
cagattcttc gtgccatcct cagtaagatg cagcaggcag agacgctcag tgtcatgcag   1320
tccctgatca tggtgttcgc tcatctggtg cacactcagc tagaacctct cttggagttc   1380
ctgtgtagcc tcccaggacc tactggcaaa cctgctctag agtttgtgat ggctgagtgg   1440
acaagccgac agcacctgtt ctatggacag tatgaaggca aagtcagctc tgtggcactc   1500
tgtaagctgc tccagcatgg catcaatgca gatgacaaac ggctacagga tatccgtgtg   1560
aagggagagg agatctacag catggatgag ggcatccgca cccgctctaa gtcagccaaa   1620
aacccagaac gctggacaaa cattcctttg ctggtcaaga tcctaaagct gatcatcaac   1680
gagctctcca acgtcatgga ggctaatgcc gctcgccagg ccactcctgc agagtggagt   1740
caagatgact ccaatgatat gtgggaggac caggaggagg aagaggagga ggaggaggat   1800
ggtttagctg gccaactttt atctgacatt cttgctacaa gtaaatatga ggaggattac   1860
tacgaggatg atgaggaaga tgaccctgat gccctgaagg atcctctcta tcagattgat   1920
ctgcaggcat atctcacaga tttcctctgc cagtttgctc agcagccctg ctacataatg   1980
ttttcaggcc accttaatga caatgagagg cgagttctac agaccatcgg catctaaaaa   2040
ggggagcctt tctacatttg ctccttctgg gccagccgca aaccattttg cagccctcac   2100
tggccttgag atgcactttc ttctcaacct aaagtggcat cttgaccctt ggcccttggc   2160
ytcggcagtg acactgatga caattcagac caggytcacc ggtgccgtca cttaggaatg   2220
ctggaacaaa ggacatttct caaagttccc ctgaagacat gccatctcta gaaccttttt   2280
tctccccgac tctaccccca cctctgttcc tagagccctc tgctggcgag tccagaaaca   2340
ttattgscca gaaggattat gngnttatgg attattttgc cccgc                   2385

<210> 768
<211> 1161
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1058)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1059)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1145)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1156)
<223> n equals a,t,g, or c

<400> 768
tcgacccacg cgtccgggct tatattcttc tttatagtct tctgaacttg gacaacaatt     60
tacttttata gttgtagaaa actgttaagc tctgttggaa cgcagttttg agaggaatca    120
atttgtgcag ctcagttcgg tactcatgtt tgtttcccag cggtcacctt tgtcccggtg    180
tccaaggtga gcgggcaggc agaggtggac gacatcctcg cggcagtccg cccgaccaca    240
cgcctcgtga ccatcatgct ggccaacaat gagactggca ttgtcatgcc tgtccctgaa    300
atcagtcagc gcattaaagc cctgaaccag gaacgggtgg cagctgggct acctcccatc    360
ctcgtgcaca cggatgctgc acaggccttg gggaagcagc gcgtggatgt ggaggacctg    420
ggcgtggact tccttacaat cgtggggcac aagttttatg gtcccaggat tggcgcactt    480
tatatacgag gacttggtga atttacccct ctctacccta tgctatttgg aggtggacaa    540
gaacggaatt tcaggccagg gacagagaac accccaatga ttgctggcct tgggaaggcc    600
gcggagctgg tgacccagaa ctgcgaggct tatgaggccc acatgaggga cgtccgcgac    660
tacctggaag agaggctgga agctgaattc ggtcagaaga gaatccatct gaatagccag    720
tttccaggca cccagcggct tcccaatacc tgtaactttt ccatccgggg accccggctt    780
caaggccacg tggtgcttgc gcagtgccga gtgctgatgg ccagtgtggg ggccgcgtgc    840
cactcggacc acggggacca gccgtcccca gtgctgctga gctacggtgt ccccttcgac    900
gtggccagga acgcgctccg gctcagcgtg ggccgcagca ccaccagggc cgaggtggac    960
ctcgtcgtgc aggacctgaa gcaggccgtg gcgcagctgg aggaccaggc ctagcactgg   1020
ggccgcttcc caccccgctt ctgggaagcc cgtggcanng gcacagggtt gtcccttcaa   1080
gtttccttct tgaagggctt gtgccaagga atgactgtct taatggcccc cctctggcat   1140
tttgntcctt ggaatngccc a                                             1161

<210> 769
<211> 670
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (670)
<223> n equals a,t,g, or c

<400> 769
gccactctga gctcaccctt ctgtctgccc gggccctacc ccttccccta ctctcaccct     60
tataatcctt ttcagcacta ggtcttcccg tcacctccac ctctctccat gacccggctc    120
tgcttaccca gacccgaagc acgtgaggat ccgatcccag ttcctccaag gggcctgggt    180
gctggggagg ggtcaggtag tccagtgcgt ccacctgtat ccacctgggg ccctagctgg    240
gcccagctcc tggacagtgt cctatggctg ggggcactag gactgacaat ccaggcagtc    300
ttttccacca ctggcccagc cctgctgctg cttctggtca gcttcctcac ctttgacctg    360
ctccataggc ccgcaggtca cactctgcca cagcgcaaac ttctcaccag gggccagagt    420
cagggggccg gtgaaggtcc tggacagcag gaggctctac tcctgcaaat gggtacagtc    480
tcaggacaac ttagcctcca ggacgcactg ctgctgctgc tcatggggct gggcccgctc    540
ctgagagcct gtggcatgcc cttgaccctg cttggcctgg ctttctgcct ccatccttgg    600
gcctgagagc ccctccccac aactcagtgt ccttcaaata tacaatgacc acccttctaa    660
aaaaaaaaan                                                           670

<210> 770
<211> 1351
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1293)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1301)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1306)
<223> n equals a,t,g, or c

<400> 770
cacgagtgtg aggggagagg gagcagcctg cagggccagg cgctgaggat cacgcatcct     60
gtgactctcc cctgtccccc gccaccctct gaaccactgg ccaccatggc tacttcaaag    120
ttgcccgtgg tgcctgggga ggaggaaaac accatcctta tggccaagga aaggctggag    180
gccctgcgca cagcctttga gtcgggtgac ctcccccagg ccgcctctca cctccaggag    240
ctgctggcct ccacggaaag catccgcctg gaggtgggcg tcacgggcga gtcgggcgcg    300
ggcaagtcct ccctcatcaa tgccctgcgt ggcctggagg ccgaggaccc tggcgcggct    360
ctcacgggcg tcatggagac cacgatgcaa ccgtcgccct atccacaccc acagttccct    420
gacgtgaccc tctgggacct gccaggagcc ggctctccag gctgcccggc tgacaagtac    480
ctaaagcagg tagacttcag ccgctatgac ttcttcctgc tggtctcccc ccgccgctgc    540
ggggccgtcg agacccgcct ggccgctgag atcctgtgcc agggcaagaa gttctacttt    600
gtgcgcacca aggtggacga ggacctggcg gccacgcgca cccagcggcc gtcgggcttc    660
agagaggccg ctgtcctgca ggagatccga gaccactgtg ccgagcggct gcgggaggcc    720
ggcgtggctg accctcgcat cttcctggtg tccaacctct cgccggcccg ctacgacttt    780
cccacgctgg tgtccacctg ggagcacgac ctgccctccc accggcgcca cgctggcctg    840
ctgtcgctcc ccgacatctc gctggaggcc ttgcagaaga agaaggccat gcttcaagag    900
caagtcctca agaccgccct ggtgttgggc gtcatccagg ccctgccggt cccagggctg    960
gcggccgcct acgatgatgc gttgctcatc cactcactgc gtggctacca ccgcagcttt   1020
ggtctggacg acgactcgct ggccaagctg gccgagcagg tgggcaaaca ggcaggtgac   1080
ctgcgctcgg tcatccgctc cccactggcc aacgaggtct cgcctgagac tgtcctgcgg   1140
ctctattccc agtcgtccga cggcgccatg cgggtggccc gcgcctttga gaggggcatc   1200
cctgtgtttg ggacgctggt ggctggcggc atcagctttt ggcgctgtct acaccatgct   1260
ccaaggctgs ctcaacgaag aakggcttga rgnacgccca ncgtgntccc gcatcaaggs   1320
cctggargat gacgagcccc aaccggaagt c                                  1351

<210> 771
<211> 2376
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (265)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (474)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1846)
<223> n equals a,t,g, or c

<400> 771
gcaaaaggct gaaggactca gctgtgctgg accagtcggc caagtactac cacctgaccc     60
acgatgagct catcagcctg ctcctgcagc gggagcggga gctgagccag cgggacgagc    120
atgtgcagga gctggagagc tacatcgacc ggctgctggt gcggatcatg gagacctcac    180
ccacgctgct gcagatcccc ccgggccccc ccaaatagcc ttcctcaccc tacccccagg    240
agggttggca tggacctatt gctgnctgcc ctctctcctc ctgaactctc tcatctgcag    300
tggggcatcg tctgtcttgc cttgtcactc cttgctcctc tccctcctgc ctcaactggg    360
gctgctggaa gggggccctc tggattccct ttggaggcat caggttctgt gcacaacttg    420
tgtgtctttg ggagccctgg gtctttccca cctgcctgkt ttcatatccc tcanctttgg    480
gggccccagg gaattggaac tcttccccaa gacagagcag gggtgaactg tagcttgatg    540
cagtaatctg ggacaagact ggttgctagc acatacttta ttatccccca aggatggtca    600
gccatttctt cccacagcca aagccccatc cccttcattt ccctccagtc cctggagggg    660
cttctagtat tactgggaca atgaccacgc tgcctgtttg tctgtgagtt acgggcaacc    720
agcctcttca gcctcacacc cattcccctg agagcaagaa gcctgtgtgg tctgggccag    780
tctctgccat gtcctgagtc tgcttcagtc tggagctgtt tgtggggcga gtgccatgtg    840
gacagtggtg gatgatgtgt gtgcttcagg ctgctccctg acccctctga cctttccacg    900
agtgtcacat gggaatgtgt ggggcgcagg ggcgggtgcg gagagagcac ctttttgctt    960
ttcgagctct tgaccacctc caatgtgtag gtccctccag gctggggctt gggactgctt   1020
atgatttggg gatcaagcct ccatgtctrt tcttgttgcc tgtccagatg ccaaaactct   1080
gtgttgctgc agggtttgaa cttttggaaa ccaattaaaa tgtgcctttg gtgggcgggg   1140
tcaagagccc ctggatgtcg acctctcccg ctgtgtggcg tccccctccc acctgttgaa   1200
tacataggga tggctctctc agggccctgg gaatgggaat ggacagcrct gctgtgggct   1260
gttcccctcc cctaaagtta atctcttggt ctggccaagt tgctgctccc tcaaccttcc   1320
tgctgtcttc ccctccctca accccaatag gaggatccca ggataaacac tgctgggcag   1380
gcgggcaggc aggcctgggg ctgccctgct cactctcatt gtctggcctc aggacttagc   1440
catactagac cagtcagctt gcctggaaga gggaggtccc actatgcctt tgggagacac   1500
ctatacttag gaaaaagcct ttgttgtcct cccatccatc cattaagctg ctatctcagc   1560
ctgtcccttc tgccccaggg gcttgcctgg cttggctgca gtgcactttg aaatgaagta   1620
tctgtccttt ggcccagccc ctggtttgct tgtagaaaac atggtaggct tccccaaggc   1680
atctgcaggg aactttggca gcttggggca ccctgaatta gcaaaaatgg ggggtgatga   1740
ggtgctgaag aaggatactt aacagcttag tgaggaggca agagctcctc tgggaccacc   1800
acttcttcag gagagggcct gtgggcttgc ttttggaagg cctcangcag acacgtgccc   1860
tctgggtgat gtctgtctgc tgccaggatg gagcagagga gcgccacaca tggaggaaag   1920
cccctgtaac gttacctacc ttaaactcca ctcatcaaat ctgagaaaag tatccactgg   1980
tccccagggt ttcagtcatg cttttggggg tcattgggta ttagagaagt aagtatcttt   2040
tctgagagag ggggagtcac cccccctact ggggattcct ctgggcttta ttcactccca   2100
gccctggccc tgacctttgt gggcctccct aatgcccagg gcatggatgg cttcagagga   2160
gtttttgaat cgaagcccag ggtccttgtt gatgtttctt ctcckagcca cacttggagg   2220
aaagttgcag gtgggttggg cagggagcag gcatggttct gctttgctgt ttgtcttcct   2280
agttaaggct ctttataaag agcttsttct tcatgtttta agcactttat gaagaataaa   2340
acattcatgt actgcaaaaa aaaaaaaaaa aaaaaa                             2376

<210> 772
<211> 977
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (970)
<223> n equals a,t,g, or c

<400> 772
gcatctactt accgaggttt tttaccaatg gctgtggcgc ccagctgtct tcctgctagc     60
caggagccca tctcgctggc cagctgcgcc atggctgatc tggttccaga cttgcagccc    120
attcttttct ggatgtctaa ctccatcgag ctcctgtact ttatccagca gaaatgccca    180
ctctacatgc agagcatgga ggagcagctg gacatcacag gctcgaagga atcgctgttc    240
tcctgcacgc tgacggccag cgaggaggcc atggcggtgc tggaggaggt ggtgctgtac    300
gccttccagc agtgcgtcta ctatgtctcc aagtccctgt acatctgcct cccggcactc    360
ctggartgcc cgccattcca gacggagcgc cgtgagagct ggtcctcggc ccccgaactg    420
cccgaggagc tgcgccgcgt ggtgtctgtg taccaggcag ccctggacct cctgcggcag    480
ctgcaggtgc accccgaggt ggcctcgcag atgctcgcct amctcttctt cttctccggg    540
acactgcttc tcaaccarct cctcgacagg ggcccctccc tgagctgctt ccactggccc    600
agaggtgtcc aggcctgcgc ccgcctgcag cagctcctgg agtggatgcg gagcgccggc    660
ttcggggcgg ctggagagca cttcttccag aagctctcct gcaccctcaa cctgctggcc    720
acacccaggg cccmsctcat ccagatgagc tggacagccc tgcgggctgc gttccccgca    780
ctgagcccag cacagctgca ccggctgctg actcactacc agctggsctc ggccatgggc    840
cccatgarca cctgggaacc aggggccmag gacagccccr aggccttcar gtcaraggat    900
gttctggagt cctacgaaaa ccccccaccc atcgtcctgc ccagcgacgg cttccaggtg    960
gacttggaan ccaactg                                                   977

<210> 773
<211> 459
<212> DNA
<213> Homo sapiens

<400> 773
gacccgccaa caagagggcc acagtggcct gtggcaggaa tgcaaccacg gcatctgctc     60
cagcatcccc tgccagacca cgctggcggt gactgtggcg tgcatggtgc tggcggtggg    120
tgtcggcgtg gtgggcatgg tgatgggact gcggattcgg tgcgacgagg gcgagtcgct    180
gcggggccag accacgagcg ccttcctctt cctcggcgga ctgctgctgc tgaccgcctt    240
gataggctac accgtgaaga atgcgtggaa gaacaacgtc ttcttctctt ggtcctattt    300
ttctgggtgg ctggccttac ccttctcaat tctcgcgggc ttctgctttc tgctggcaga    360
catgatcatg cagagcaccg acgccatcag tggattcccc gtgtgtctgt gactgcagcc    420
tgcctggggc agaataaagg aacggctttt tttagcaaa                           459

<210> 774
<211> 1110
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (280)
<223> n equals a,t,g, or c

<400> 774
gaagtgcatg agcaccagcg cgtcggcgct gctggcctgc gtgcgcgagg tgaaggtggc     60
gcccagtgag ctggcgcgca gccgctgtgc gctcttcagc gggcccctgg tgcaggcagt    120
gagcgccctg gtaggcttcg ccaccgagcc gcagttcctg ggtcgcgcgg cagctgtgag    180
cgccgagggc aaggcggtgc agaccgccat cctgggcggc gccatgagcg tggtgtcggc    240
ctgcgtgctc ctgacccagt gcctcaggga tctggcgcan accccgacgg ggcgccaaga    300
tgtcggacca cagggagagg ctgaggaact cggcctgcgc cgtgtctgaa ggctgcaccc    360
tgctatctca ggctttaagg gagaggtctt cgcccaggac tttaccgcca gtgaattcca    420
attctgtgaa ttagcacccc acccccatac cccttcttcc acccccagac taaaggaaga    480
tacttactct ctgcccctct ccatttatac caaagaaatc ataggtgaaa cccctaccct    540
ccccaacgtt aaatgctcga gaggaatctt ccacaaggca gggccatgca cgcaacctgc    600
acacgcactt ggagggccca ggtgtctctc caccagcccc catgcagtag ggactggaag    660
atatgtcatc tgctggttgt gttatcactc ccacccccta ccccagcccg tsttccggaa    720
tttctcaact aaatttcatt attgggcagg aaggaggtca tgggttcatt tcatttttgt    780
tttttgtgtt tttaattaaa agaaaggtta cctcagtttt cactccttag acatggatgt    840
agctaccttt ttttgtatgt cttttttttt ttaagcaatc gtgttgaatt aggagtatac    900
ttggtgtgga aagagtatga atttgccatg tgatttgcaa atggggggaa gctactgtga    960
gcgtgtgttt ttttaattta cactatagag tgattttttt ttcccccaac gtcaagtttt   1020
taccttgcat gtactggagt atttatttca tctattaaaa tgttatgttt ctcagaaaaa   1080
aaaaaaaaaa aaaaaaaaaa aaaaactcga                                    1110

<210> 775
<211> 870
<212> DNA
<213> Homo sapiens

<400> 775
tttttttgag agaacytgaa catttaatat ggtcagcacc ttgtaaggtg aaggtgtgtt     60
ttttacacaa attataaata atgaaaaata tgcatttaga aaaagaagca gcagtcccct    120
tggcgggccg gctcgaggac tctttggttg agtggcaggt gaggccctgg gtccagggtc    180
tgtcagagcc cccctaggtc atctgccagg aaggccagca ggtagcggct gacatgtctg    240
tcgatgatga caggcgagaa accgaggacg cgccgggtcc ctggcaggcc cttggggtct    300
ggcggatagc agtacaggag cagggccagt cccacagcaa ggcccaggcc agccaggaag    360
ctcatgggtc ccctgttact cagctcgccg ctctggctgc ccgagtctag ctctgtgcaa    420
tctgagttct gcagagcgtg gcggctgggc aggcggctgt gcaggggctg ggcatggata    480
tacagggctc ggtagaactc ctggcagtcc cgctcamcgc tccgctgcag gtggctcagg    540
aggtcacara gccgcacacg caaggatgcc ttggggttcc ggaacttttc cgcctccttg    600
ttggtaagga tctgtgggta gtaacggttc agctggagga tgatcctgtc cacctgctgc    660
tcactcaagc gcccatggcc tgtcaggaaa ggcgtgtcct gcaccaggcg gtcacaatag    720
gtctgatctg tcatggcgac ggacacagcg ccgcccgcag tccccagcgg tctgccccgc    780
cgcgcgtccg cccctcggtc agccgcccgg tccaccagct ccagcgatam gcccccgggg    840
ccgtgctcgc ccgccccttt tggctaggcc                                     870

<210> 776
<211> 3167
<212> DNA
<213> Homo sapiens

<400> 776
tttttttttt ttttttttga cagatcttga caatgtcctt ttaattgtac tcttttcaaa     60
aaatctcctt tctcagttaa aaaagacaag gcatgatgaa gacctgctct agcccatact    120
gggsggtgat ctcggtcctg ggggaggcca ggccggactc ttccaaggcc tcctccctgg    180
gcagtcccag caatggggcc agtggcaggg caggttctcc ctgccagaac ccgatcctag    240
cccttcagaa ggactggacc tctgtgtccc ttcagtggga agccaccttg gacacacgca    300
gtcattcagg tggacataag gccactcttc tcgcccttga ccttgaggaa ctcagccatg    360
ctggagaaat acttctggtt ggcctcagcc accttcttct ctgccgcctg tgggttcaca    420
atctccaggc cctggagtgg ggtgaaggcc acgctggagg ccgtgcccga ggagcggtcg    480
cggatggtgg acttcccgcc atatacgacg ctctgcttct gcagggtcgc tgcagcgtct    540
tggagatcct ggccttggtg gcctcgttta cctgtgtctg ccgcacacgc ccactgcccg    600
acttgcccag gtggcccagg ctgaatccca ggtcctcctg gtaggcgtcc tcctcgatct    660
ctccgaagct catacggttg gcctgcttcc ggatctccgt cagccccagc cgctccttca    720
tcttgcggta ctgcggccgc ctcgcttctt ccgctgtcca tccaggggcg caggcagcgg    780
cttcacctgc ttcacaggcg gcggctcctg ccacttgtcg aatttgcgct cgatctcatc    840
cttcagttcg tagcccacct tcccttctgt gctctcgtgg aaactgtcca cacgggctgc    900
cagtgtgcac ttggcggcca ccagccgggc cgctttccgc cgcagatccg gtggcaggga    960
ctgcacgatg tcactgtggt agatgtagcc ggtgtggggc agcactgagg tagacgagaa   1020
gcccgacagc gtcttgcgct gggccccgag cagcatgatg ttgcaggcgg gcatcttgga   1080
gaggttggtc aggccgccgg ccacacccat gatcttggcg gccgtggatg ccccgataat   1140
gatggacagg ttgggtgcga tgaaggacat ccgggactcc acatactcgt agatgcggtg   1200
cttggaggcg ttcagctcca gcgccatgtc gcaggcctcc tccagccgct ccagctcctc   1260
ctccgacagc tgctgcccct gggtggtgga ggcggtgacg ctgacgacca tgatggtggc   1320
attggtgagg atctgctgca ggttctcatt gttcttgcac ttgtccaggc tgttgcccag   1380
ctccttgacc gtgcggatgt aatccagtgc attggggacc aaggactcca gttcagggaa   1440
tctctttgag tacttatccc ggatgaactt atggatgatg ttcagctcgt tttcgatctc   1500
cacggtcagg ttgttggcat ccacgatgac gcggtattca ggcgcggcct ccactggtcc   1560
catcacttct gaagctttgg cttgcttgct gatatactcc tcaatcttca tcataatctc   1620
agcaaacatc ttactatccc atagcttggc gatggtcttg actgaatccc cggaaagatc   1680
cagctgtgtc tcctcctgca catcctcgat cgctggctcc tcttcttcct ccccatagct   1740
tcctccttcc tcctcttctg ctgcctcttc gagatcagct aagagctcat ctgccagaga   1800
catcccgagg cctctcctct ccgcgcacca ctgtttctag cgttagtcgc tcaccgatga   1860
cgtctcactc tcgcgccgtt atagaggcaa agctactctc tgattggtcc ccgctcgcga   1920
tgttcctggc cgcatttgaa acaacaactt tattagcacc tggcactagg cggagagarg   1980
cggtaagccg cgaggaggaa agggactcac gtcccgctgt ggaccgatcc tgctaagcag   2040
agaatcgctg tggccggacg acggggcgtc gagacaagaa gaaagacgtt ggcaactcag   2100
aggactggtt gcggcgttag acaagaaagc aaggccttta agcagggatt cggggtggac   2160
gtgggggtgg gccgaagcga accggaaaca ggaaactaca actcccacaa ggcctagggc   2220
cacgtcccgc cgtcctcggc tgctgagcct gatgggacaa gtagttttgc gaacggctta   2280
acctacagat tgaagaggtc ggaagctctg aggcccgggg cttccggagg tcgcggagat   2340
ggaattggag cagagagaag ggaccatggc agccgtgggc tttgaggagt tctcagcgcc   2400
gccagctcag agttggcgtt gcctccccta tttggtggcc acatcctgga gagcgagctg   2460
gagacggaag tggagtttgt gtcaggtggt ctgggcggct cagggctccg ggagcgagat   2520
gaagaggaag aggcagcccg gggtcggcgg cggcgccagc gggaattaaa tcgcagaaag   2580
taccaggcac taggtcggcg ctgccgggag atcgagcagg tgaacgagcg ggtcctgaac   2640
aggctccatc aggtgcagag gataactcgg aggctgcagc aggaacggag gttcctcatg   2700
agagtgctgg actcctacgg ggatgactac cgggccagcc agttcaccat tgtgctggag   2760
gatgagggca gccagggcac ggatgccccc accccaggca atgcggagaa tgagcctcca   2820
gagaaagaga cactgtcccc gcccagaagg actcctgcac ccccagaacc cggcagccca   2880
gcccccggtg aggggcccag tgggcggaag aggcggcgag tgccacggga tggacgccga   2940
gcaggaaatg cgctgactcc agagctggcc ccggtgcaga ttaaggttga ggaagacttt   3000
ggctttgaag cagatgaggc cctggattcc agttgggttt ctcggggtcc agacaaactg   3060
ctgccctacc cgaccctggc cagcccagcc tctgactgac gcatgcccaa taaactgacc   3120
ccacactcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                 3167

<210> 777
<211> 742
<212> DNA
<213> Homo sapiens

<400> 777
gttttactgt ttacaatgtg gtttaatgag aattggaact agccctacta ttagcagaca     60
gcatcagggc ggaggccccc agcccagacc ccatggtctt ccccatcccg aagtgggatg    120
gatttcctca tctgcataca cagcacttcg tcgatataaa tggtgttctc tttgacctgg    180
atctcctcct gcagggcaag ctgtctgcga tgcagccctt tcagctctgc ctgagcttgg    240
gctaaagttt ccttcaatct tgcgacattg tgggtgatct cttgaacctc cttcattagc    300
ctatattgtg cgacatcacg acacagctcc acgttcggcc ggtgtgtcct ggtctccaag    360
cgcgtatgag ccaccttggc tggcccttct tggtcaagga tggccttttc aagagctgta    420
atatttttct cctgggaagc aatctcttcc atgaccttgg ccagatgatc agccagcttg    480
tccctggcat cctttgtatc cttcagccca ttcttgaatg ccgtgtccac cacatcacac    540
tgcttgcrca gatcattggc tgtctgggac aggattcgat ccaccagggc tttcagcatc    600
agggagttgt tccgctgctt gtcagccttc tccacattgg tgctggagaa gtccaaccag    660
tcttccagac tcacggagtt tggctcaatc ctcacggcgt tctcagaata tctgatgttt    720
ggtgagttgt tgttgagcga gc                                             742

<210> 778
<211> 1296
<212> DNA
<213> Homo sapiens

<400> 778
ctccaatcca ccacacacsa gccttacccc tctgctggca agaggggacc tgattcatcc     60
tcacgctaaa cactcattct acccaactga ttgagacaga acagaagata aactgaaact    120
tctctgcctt cccgctgcaa gagtgaatga gcgatccctc tcaactgact caaaatgttt    180
gcctcaccca ggagatggag ctctcgaagg ccttctctgg ccagcggaca ctcctatctg    240
ccatcctcag catgctatca ctcagcttct ccacaacatc cctgctcagc aactactggt    300
ttgtgggcac acagaaggtg cccaagcccc tgtgcgagaa aggtctggca gccaagtgct    360
ttgacatgcc agtgtccctg gatggagata ccaacacatc cacccaggag gtggtacaat    420
acaactggga gactggggat gaccggttct ccttccggag cttccggagt ggcatgtggc    480
tatcctgtga ggaaactgtg gaagaaccag gggagaggtg ccgaagtttc attgaactta    540
caccaccagc caagagagaa aatcctatgg ttatccctgg gaacgcagat cacctacatc    600
ggacttcaat tcatcagctt cctcctgcta ctaacagact tgctactcac tgggaaccct    660
gcctgtgggc tcaaactgag cgcctttgct gctgtttcct ctgtcctgtc aggtctcctg    720
gggatggtgg cccacatgat gtattcacaa gtcttccaag cgactgtcaa cttgggtcca    780
gaagactgga gaccacatgt ttggaattat ggctgggcct tctacatggc ctggctctcc    840
ttcacctgct gcatggcgtc ggctgtcacc accttcaaca cgtacaccag gatggtgctg    900
gagttcaagt gcaagcatag taagagcttc aaggaaaacc cgaactgcct accacatcac    960
catcagtgtt tccctcggcg gctgtcaagt gcagccccca ccgtgggtcc tttgaccagc   1020
taccaccagt atcataatca gcccatccac tctgtctctg agggagtcga cttctactcc   1080
gagctgcgga acaagggatt tcaaagaggg gccagccagg agctgaaaga agcagttagg   1140
tcatctgtag aggaagagca gtgttaggag ttaagcgggt ttggggagta ggcttgagcc   1200
ctaccttaca cgtctgctga ttatcaacat gtgcttaagc caaaaaaaaa aaaaaaaaaa   1260
aaaaaaaaaa actcgagggg gggcccggta cccaat                             1296

<210> 779
<211> 3751
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2279)
<223> n equals a,t,g, or c

<400> 779
gcatgaacga aatgtggatc cttcacctgt gggtgagtct aagcaccgcc caggtcagtc     60
ttcagctcct gctcctccac ctcgtcttaa cccctccgcc tcctcgccaa acttttttaa    120
gtacctaaaa cataattcca gtggagaaca aagtgggaat gctgtgccaa agagcatctc    180
ctaccgtaat gccctgcgga aaaaacttca ttcttcttcc tctgtgccaa attttctaaa    240
atttctggct cctgtagatg aaaataacac ctctgatttt atgaacacaa aaagggactt    300
tgaatccaaa gcaaaccatc ttggtgattc tggtgggact cctgtgaaga cccggaggca    360
ttcctggagg cagcagatat tcctccgagt agccaccccg cagaaggcgt gcgattcttc    420
cagcagatat gaagattatt cagagctggg agagcttccc ccacgatctc ctttagaacc    480
agtttgtgaa gatgggccct ttggcccccc accagaggaa aagaaaagga catctcgtga    540
gctccgagag ctgtggcaaa aggctattct tcaacagata ctgctgctta gaatggagaa    600
ggaaaatcag aagctccaag cctctgaaaa tgatttgctg aacaagcgcc tgaagctcga    660
ttatgaagaa attactccct gtcttaaaga agtaactaca gtgtgggaaa agatgcttag    720
cactccagga agatcaaaaa ttaagtttga catggaaaaa atgcactcgg ctgttgggca    780
aggtgtgcca cgtcatcacc gaggtgaaat ctggaaattt ctagctgagc aattccacct    840
taaacaccag tttcccagca aacagcagcc aaaggatgtg ccatacaaag aactcttaaa    900
gcagctgact tcccagcagc atgcgattct tattgacctt gggcgaacct ttcctacaca    960
cccatacttc tctgcccagc ttggagcagg acagctatcg ctttacaaca ttttgaaggc   1020
ctactcactt ctagaccagg aagtgggata ttgccaaggt ctcagctttg tagcaggcat   1080
tttgcttctt catatgagtg aggaagaggc gtttaaaatg ctcaagtttc tgatgtttga   1140
catggggctg cggaaacagt atcggccaga catgattatt ttacagatcc agatgtacca   1200
gctctcgagg ttgcttcatg attaccacag agacctctac aatcacctgg aggagcacga   1260
gatcggcccc agcctctacg ctgccccctg gttcctcacc atgtttgcct cacagttccc   1320
gctgggattc gtagccagag tctttgatat gatttttctt cagggaacag aggtcatatt   1380
taaagtggct ttaagtctgt tgggaagcca taagcccttg attctgcagc atgaaaacct   1440
agaaaccata gttgacttta taaaaagcac gctacccaac cttggcttgg tacagatgga   1500
aaagaccatc aatcaggtat ttgaaatgga catcgctaaa cagttacaag cttatgaagt   1560
tgagtaccac gtccttcaag aagaacttat cgattcctct cctctcagtg acaaccaaag   1620
aatggataaa ttagagaaaa ccaacagcag cttacgcaaa cagaaccttg acctccttga   1680
acagttgcag gtggcaaatg gtaggatcca aagccttgag gccaccattg agaagctcct   1740
gagcagtgag agcaagctga agcaggccat gcttacctta gaactggagc ggtcggccct   1800
gctgcagacg gtggaggagc tgcggcggcg gagcgcagag cccagcgacc gggagcctga   1860
gtgcacgcag cccgagccac gggcgactga cagctctgca ggagagattg caacaccatc   1920
ccacactgtc caggccttaa ctgagaggga cagaagacgc tggaaggaga gaaggaagcg   1980
ggaagtgtgc ttctcaggga ggaaaccggc ttgccagcaa gtagattctt acgaactcca   2040
acttgcaatt cagggggcat gtcccagtgt tttttttgtt gtttttagat actaaatcgt   2100
cccttctcca gtcctgatta ctgtacacag tagctttaga tggcgtggac gtgaataaat   2160
gcaacttatg ttttcttgtt ggttcctttt tgagtgtcac tgtgtttgta aagagcattc   2220
acaatacggt ggaatttcaa aagctggaag agctcgagat catgcctcar gcaaaggcng   2280
tgggtccatc gttcttccga gagggtttgt gtggcgacta caccctcagc gtccctggca   2340
aggtgcagta tgtctcgccc attcttgtta tggaaaccta agatgatcat tgggaagatc   2400
agtgatcttg ggtcattgat ccctggctca gaggatagcg gtttccatca taaaccaaga   2460
tgatgagttc agcctttatc cctcgtggtt ccactagatg taacttaaag gagttaacat   2520
ttgaggactt tgttctacat cagattttac tatttgaatg tttaagatca ctttattgaa   2580
tttgaagatc atcaaattaa ataaaatgat ttatttaatt tggatatcct gatcactgtc   2640
aagtgaaatg gatctctctc tttggtattt aaggaagttt gtctttaaaa aaaaaataga   2700
gtgttttcat acatttttgc ttatcccata agtacagttg atcaaagtca tagtaggtaa   2760
atgctttatg ggacagctga caccttttag accctaccag gtattgctag catgtgagct   2820
gcagttgtgg ggtctgagat atttctttgt ggtagtttca tacccatact atagagtcat   2880
gtatttattt ttscctgttg tgtgatgtaa tgcaatcatg ttcctttgag tctccatccc   2940
ttggaaatct gacttcttgc agaaggagta ggcacatcaa gatattcagg ggtgccccaa   3000
gagtctggga ctttcaaaaa aaaaagatca ggctgaaact gcagtcagat ttatgacagc   3060
tgacagtttt tcagaggtcg cacacagtga ctctcctctc tcaggatgac gaggacctgt   3120
gccttcaaca agcaaaatgc tgctcacggt tgtcctgctt gcagccagtc actgtgtaaa   3180
gcctctctga tgtgcactta agagtgggtt gctttctcac aaagatgggg ttctgtgcag   3240
tcacaggtca cttccttgac aacacaatca tttctgatct ttatcactgt aaccacgtct   3300
tctattccat aggagtttct tttgattctc tcagttgcgg gggcatctct taatcctggg   3360
gtaaaaggag agattgccat acttagactc actgtgagtc tccccggcca tttcacgagg   3420
agaccacagt gctgccacca gtgcctaaac aggtggctgg cattcgagac ttcctcctgt   3480
tccctgggtc agaggatagc ggtttccatc ataaaccaag atgatgagtt cagcctttat   3540
ccctcgtggt tccgctagat gtaacttata ggagttaaca tttgaggact ttgttctgca   3600
tcagatctta ctatttgaat gtttactgtt ggattttggg catcttatta ctgttactca   3660
aaaacattga ctctgcatca agaaagaaac aagaaagcaa taaaacaaga aataattcat   3720
gctcacaaaa aaaaaaaaaa aaaaaaaaaa a                                  3751

<210> 780
<211> 498
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (495)
<223> n equals a,t,g, or c

<400> 780
gaaatttaga aactgtatgt atagcttcat gtttttcata aaataggaat gaggacaaat     60
gttgctcttc atcctaccag ctgtttgttc tttggtaggg gatcatgagt ggaaaaacaa    120
aggcaagaag ggctgccatg ttttttagac gttgctctga agacgccagc ggtagcgcca    180
gtggcaatgc tttgttatca gaggacgaaa atcctgatgc gaatggggta actcgatcat    240
ggaagattat tctaagtaca atgcttacac tgacttttct tcttgtagga ctcctaaatc    300
atcagtggct taaagaaaca gatgttcctc agaaatccag acaattatat gccataattg    360
cagaatatgg ttcaaggctt tataaatatc aggccagact tcgtatgcct aaagagcaac    420
tggaactttt aaagaaggaa agccagaatc tggaaaacaa ttttcgtcaa awtctatttt    480
tgatcgaaca aatanatg                                                  498

<210> 781
<211> 589
<212> DNA
<213> Homo sapiens

<400> 781
ggcacgagct ggctcagggc tacctccttc cgcctaggac ccccccttcg gggcaagatg     60
gcctgtcgga gccagagggc atctctctga agcgggtcgc tgtggtggaa gatttctttg    120
acatcatcta ctcgatgcat gtggagagct cagcggagcc aggcaaagcc cccaagcacg    180
ctgggcagaa gaaaacctac cgagcgatcg cagagaccta tgccttcctc ccgagagagg    240
ccgtgacccg gttcctgatg agctgtacgg agtgtcagaa gaggatgcac tttaactcca    300
atggcctgga acccaaagaa aacgagcctc catctccact ggtctctggg attattgatt    360
acaacatgcc cctcacctcc acctacctga agcagatgaa gcttcgagtg atgaattccc    420
aggagcagcc atcctcactg tctccggcac ctggcttcgt aaacactgtt atcaccgtgc    480
tcatctgtgc ccatgaagaa tgaagcacaa aaccgcacaa acagccggaa gcacagcccc    540
ctggttttgt ttcatacaga atggcactaa atccaggtca ccactaaaa                589

<210> 782
<211> 1493
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (37)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1352)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1451)
<223> n equals a,t,g, or c

<400> 782
tttttctctt ctctaacgat gntgaatcct ctgaganagc tctttaagct gatggcctct     60
ctgtttctgt cggtgttcac acttggcctt ccctttgccc tctttcagta ttatgcctac    120
acccaattct gtctgccagg ctcagcccgc cccattcctg agcctttggt acagttagct    180
gtagacaagg gctaccggat tgcagaggga aatgaaccgc cttggtgctt ctgggatgtt    240
ccactamtat acagctataw cyaggatgtc tactggaatg ttggcttttt gaaatactat    300
gagctcaagc aggtgcccaa ttttctactg gctgcaccag tggctatact ggttgcctgg    360
gaacttggac atacgtgacc actcaccctt ggctctgctt acacttgggc tgcaaaggag    420
caagaacaat aagaccctag agaagcccga tcttggattc ctcagtcctc aggtgtttgt    480
gtacgtggtc cacgctgcag tgctgctgct gtttggaggt ctgtgcatgc atgttcaggt    540
tctcaccagg tttttgggct cctccactcc tattatgtac tggtttccag ctcacttgct    600
tcaggatcaa gagccgctgt tgagatcctt aaagactgtg ccttggaagc ctcttgcaga    660
ggactcccca ccaggacaaa aggtccccag aaatcctatc atgggacttt tgtatcactg    720
gaaaacctgt tctccagtca cacgatacat tctaggctac ttcctgactt actggctcct    780
gggactactc ctacattgca acttcctgcc ttggacatga cctggactct ccagggacag    840
gttggaagcc aacttaaccc aggggtctga aagtaaaaat acacattgga actgcctctg    900
ctgccctggg atcattactg tgtccattat aatctttctc tttctctttg aaagctggtc    960
aggaatggga gaagtgtcag acactagaga gccccttctg gtcctggcta gggcaaattt   1020
tagacaacta ttttctctgt aagtgaagat tgtcgtattc caagtctaaa atacacctgg   1080
atctgtctag tcaatcaaca tagcagagac agtcttaaac ctaccattga cctgtgtgta   1140
aatttaaatg tcaatttatt gaagtgtaaa tttcatcaaa ggcattagct gacaggctgg   1200
taacagtcca cacaagatgg tataggcctg aacagtgtag tggcagtaat aaagtgggac   1260
cattttttcc aaatgcgcat gttctgatgt ttttatgatg tgaggattta ttgaaaactc   1320
aagttcgata ctctcagtac atgaaaaaaa anaagaagaa aaaaaaaaag tttttgccgg   1380
gtcctttggt tcttcctggg tctgggctcg cctagggacc tcgggatggc cgcctatcga   1440
gggctcgcgg nggcggtccg gtgtttgccc agggtccaag gtctgtccgc ttg          1493

<210> 783
<211> 563
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (437)
<223> n equals a,t,g, or c

<400> 783
tgaatagcaa gccaagaact tcagaattta ccttctaatg aacaagaacc agtgaagatt     60
tatgatgtgg taacatgacc aaagtatatt tacaagatta tgctagtcat gcttgcaaat    120
agtttcaagt ggagagaggt ataagagaaa ttagggaaat atggtagaaa tctgactatt    180
cagcaagaat gctgtggaaa tgaaagatgc agaaaccaat tggccaagtt atatcaaata    240
ctctgagcac ttcataaata cttgccagtc atatccagga aaacacatat ttatcttcca    300
gataatgtgg ttggggtatc tggtartttt aaactttggt tatgtctgtc tgttcccyag    360
gcyccgaaat atycactacc tctttaatac tgscctcttc cttatcgcct ggsgccttct    420
cattgcaaga tctcagntgg ctcggaatgt ctggttcttc attgtaagct tctgttataa    480
attcctctcc tactttagag catccagcac gctcaaagtt taagagcatt tagccatcgc    540
tttttatctg gaacctctca gat                                            563

<210> 784
<211> 1303
<212> DNA
<213> Homo sapiens

<400> 784
aattcggcac atggggagaa atggtggtgc agcaagagag caggaacctg aacattgcca     60
tcataaggcc ctccattgtg ggagcaactt ggcaggagcc tttcccaggt tgggttgata    120
atataaatgg acctaatgga atcattattg cgactgggaa agggtttctt cgggccataa    180
aagctactcc aatggctgtg gcagacgtaa ttccagttga tacagtcgtc aatctcatgc    240
tagctgtagg atggtatact gcagttcaca gacctaagtc aacattagtc taccacatta    300
catctggtaa catgaatccc tgcaattggc acaaaatggg agtccaagtc ttggcaacct    360
ttgaaaaaat cccatttgag agacctttca ggaggccaaa tgctaatttt accagcaaca    420
gcttcacatc acagtactgg aatgcggtca gccaccgggc ccctgccatt atctatgact    480
gctatctgcg gctcactggg aaggaagccc agggatgaca aagctcatga atcggctttt    540
aagaactgtt tccatgttgg agtatttcat caaccggagt tgggaatgga gcacgtacaa    600
tacagaaatg ctgatgtctg agctgagtcc tgaagaccag agagtattca actttgacgt    660
gcgccagttg aactggttgg aatacattga aaattatgtt ttgggagtta aaaaatactt    720
attgaaagag gatatggctg ggatcccaaa agcaaagcaa cgcttaaaaa ggctccgaaa    780
tattcactac ctctttaata ctgccctctt ccttatcgcc tggcgccttc tcattgcaag    840
atctcagatg gctcggaatg tctggttctt cattgtaagc ttctgttata aattcctctc    900
ctactttaga gcatccagca cgctcaaagt ttaagagcat ttagccatcg ctttttatct    960
ggaacctctc agatacctct aaaacagcaa actgtgattc tcaagattag aaagtaacaa   1020
ggaatatgcc caaactgtca aatgtcacct gttatgtatt cgtccctatt ccttaactat   1080
gtatttttat ttcagtgaga gaaggaaagt tgtaaactag cccatagtca cctatatttt   1140
agggaaaaaa atccaaattg tttcctaaca ttctatttta tgcccttgcg tattaaacgt   1200
gaaagtactc ccacttttct atatttagtt tgtcttgtct cttctgtgga tgtttcattt   1260
taaacttcag ttaaatatgg aaagaatgca tgggcagagg ctg                     1303

<210> 785
<211> 2242
<212> DNA
<213> Homo sapiens

<400> 785
tcgagttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt     60
ttttttaggt gtcattttta ctttatttaa ggaaaaaagg gtggggggac aacagtaatt    120
ttcataatac acagtagaca agttagcact gcaaaaaaaa gggctgtgta cttgccacca    180
gtctgctttg cagcttttat aattagtaaa tttaatgcag tttgtcattt gtattactat    240
ttagcaaatt aataattggc aaaattaggg taagtgtgct acaactaaga cgaaaaccta    300
aataacccat aaaaagtcac ttaaaataaa ccataaatat gtggtgcgca ttagtgtaac    360
aaaaccattt ttgtaaacat tttctccaac gtaacatgtg catgagaaaa gagtaaaaaa    420
cactgcactc aatacagaaa gggttactct gattttaata cagaaaggtt attacttgtg    480
aaagctctga ctaaacctag agacattttt gktttgtttg gaagagcact cctctaacag    540
ttcaatgttc cttatgtaat ggtgtcattg caatactgtt ttcttgtgta attttgccat    600
attggcactt ctgtggagaa gttactaccc tgtaaaaggg gggaaaataa ttcctttcct    660
aaaagaatct aaacatttcg acgactccca atctttaacg gagaaacttc actgggtccc    720
tgcatcaagc tatagcaact caatctggtt gacaaggggg tgaggctaag acgggaagga    780
aaaaagccaa gtaaagcaca gaccaggaag cccccgccga gaaggacaaa gggtgttcca    840
atttcagtaa cttaagccca acaatggatt caattcagtt caccacaaac accaccagag    900
tgcccaccgg gtgcctggag ctgcacaagc aagccaagca caactcggtg tgagctcaga    960
cccctttacc acctatggga aagccagcaa gttctaagca cttggtaatt cccaatgaaa   1020
caccatttgc attttttttt gtgtaacatt tgacttacag acatggagct tcaagtcttt   1080
ggataatgtt aagaccatta tgccacatcc tttgttctct gccttctccc acttagcatc   1140
agacattgag catttcttca aagacatctg cccacctttt actgttctcc acctgtgcct   1200
ttccttcttc tcttgatatg tacacgagtg tgttcactgt ggcatgtttc atcttatgaa   1260
aagcctaaac atggatataa attacaagca ggaatttaat tctaactaaa gtcctgtggc   1320
gatggaatcc agcctacctc aaatcccttt aaaggtagga ttaatttttc aaccttctct   1380
aggttaacta caaaccagta ggcggctttg gccttcagca ctgctccaaa ctcatacaaa   1440
tgaaacatcc atttccatct tcttttactt ccccaaaaag taagcttctc agcttgtctt   1500
tacaggtata cacaaaacca ccagctgctg tgtctgcatt catgagtgga tgtacttgtc   1560
ttaccagatg tttgtagctc aaaggagggc ctttttcaaa aagatggaac caggaacagg   1620
aaactgacaa gaggtcagag tgggtgccaa gtgggatggg aagcaaacag gtacaaatgg   1680
ctgctgtgtt taggtgggtg ggagcagagg gaaaatcccc cattttcaca atatacagga   1740
aaattaacca caaaggaaaa agatcaagcc taaaaaacag caagtttctt ttgatgactg   1800
aggttaaagc agccataatg cagttatttc cactcagaac tcgacaagag gaaagtaaga   1860
tggcaggact gtgacatgga gtcctgatcc tttcctgaga cggtaatatc cttacgggag   1920
cttgagtgat gaccatgaag ccatgaaaca aattctttct caagacattt attacaaatg   1980
tcatgaatat attcataaag taaaattggt ttaaaaaaac agagaacaag agagcaagtg   2040
agaaaacgag aaaagccagg acttcgatat tacacctaaa acasaggatg cccactttat   2100
gaataagcag aattaactac attcttaaaa yagttttagt gcattgcatt tttagaaaag   2160
ggaaactccc ccacccccaa gaaaaggttc ctgcaacact gaacagtttg tgtgactatt   2220
ctaatgtaac cacctgtctg ct                                            2242

<210> 786
<211> 1077
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (189)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (694)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1046)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1061)
<223> n equals a,t,g, or c

<400> 786
tcacccagtg aagacactgt aagtctggag gtaggggaca gcaatcagag gccctttggt     60
cactgcacag ttcctttaac tgcaacccta ggctggcctg acccagctgc tgcaggntgg    120
ggaggggcca tgggaggggg tcagagccca cagcaggact gttgcataat ccttggggcc    180
tggcttggna atccaccctg gttctgaagt ttgtgctttg tgtctggttc cttccttttc    240
tgccttctct cctgctttct agctctgggc tttcccagct ccgaagtcaa tactgagatc    300
ccagatgtgt ccagagacat cctgaagagg ctcgggggtg gaggagcctt agtgtgtcca    360
caaagggact cctgaaactg actgagagcc agtggatttg ccagcagtct gagcttctac    420
cgagtcttcc cccacctcaa tccctgttgc tatggagact accaatggaa cggagacctg    480
gtatgagagc ctgcatgccg tgctgaaggc tctaaatgcc actcttcaca gcaatttgct    540
ctgccggcca gggccagggc tggggccaga caaccagact gaagaraggc gggccagcct    600
acctggccgt gatgacaact cctacatgta cattctcttt gtcatgtttc tatttgctgt    660
aactgtgggc agcctcatcc tgggatacac ccgntcccgc aaagtggaca agcgtagtga    720
cccctatcat gtgtatatca agaaccgtgt gtctatgatc taacacgaga gggctgggac    780
ggtggaagac caagacacct ggggattgcg tctggggcct ccagaactct gctgtggact    840
gcatcaggtc tcagtgtccc tatctgtaag atcaacaaga aacacggtta agggaggtcg    900
tcactggggt gggagaagag gggctggtag accgaagcct tgtgcataag gattttttcc    960
caggaaaaga tagactttat aaacagtggg agcccatgaa caaacatata aaagtagcaa   1020
cagataatga ccaataactg gttcantggc tggagtatta ngggcctggg gattgga      1077

<210> 787
<211> 569
<212> DNA
<213> Homo sapiens

<400> 787
aattcccggg tcgacccacg cgtccggctg aggcgggtgg catggcggag aaggatgaca     60
ccggagtttg acgaagaggt ggtttttgag aattctccac tttaccaata cttacaggat    120
ctgggacaca cagactttga aatatgttct tctttgtcac caaaaacaga aaaatgcaca    180
acagagggac aacaaaagcc tcctacaaga gtcctaccaa aacaaggtat cctgttaaaa    240
gtggctgaaa ccatcaaaag ttggattttt ttttctcagt gcaataagaa agatgactta    300
cttcacaagt tggatattgg attccgactc gactcattac ataccatcct gcaacaggaa    360
gtcctgttac aagaggatgt ggagctgatt gagctacttg atcccagtat cctgtctgca    420
gggcaatctc aacaacagga aaaatggaca ccttccaaca cttgctccct ggcaacccct    480
aatatttggg atctctcaat gctawttgcc ttcattagct tgctcttatg cttccacttg    540
gtggattgtg tctcctggct ggtatgggg                                      569

<210> 788
<211> 858
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (634)
<223> n equals a,t,g, or c

<400> 788
cactatcgaa gtagcctgca gtaccggtcc ggaattcccg ggtcgaccca cgcgtccggc     60
gggtggcatg gcggagaagg atgacaccgg agtttgacga agaggtggtt tttgagaatt    120
ctccacttta ccaatactta caggatctgg gacacacaga ctttgaaata tgttcttctt    180
tgtcaccaaa aacagaaaaa tgcacaacag agggrcaaca aaagcctcct acaagagtcc    240
taccaaaata cctgggatat agtaatcact caatgaatat aaactgcact tactggcatg    300
ctcaaggrat gggctattaa gcaaggtatc ctgttaaaag tggctgaaac catcaaaagt    360
tggattttkt tttctcagtg caataagaaa gatgacttac ttcacaagtt ggatattgga    420
ttccgactcg actcattaca taccatcctg caacaggaag tcctgttaca agaggatgtg    480
gagctgattg agctacttga tcccagtatc ctgtctgcag ggcaatctca acaacaggaa    540
aatggacacc ttycaacact ttgctccctg gcaaccccta atatttggga tctctcaatg    600
ctatttgcct tcattagctt gctcgttatg cttnccactt ggkggattgk gtcttcctgg    660
ctggwatggg gagtgattct atttgtgtat ctggtcataa gagctttgag attatggagg    720
acagccaaac tacaagtgac cctaaaaaaa tacagcgttc atttggaaga tatggccaca    780
aacagccgag cttttactaa cctcgtgaga aaagctttac caccatgcag gaacagactt    840
ttggtgatga ggaggaag                                                  858

<210> 789
<211> 1485
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (158)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (749)
<223> n equals a,t,g, or c

<400> 789
agctggcatc aggggccggc ctggaggtca gcgtgcaggg cccgttcctg agtgtgtccg     60
tcctgctgcc tgagaagttc ctcacccaca cccacggcct cctcgggaca ctcaacaacg    120
accccaccga cgacttcacc ctgcacagcg ggcgcgtncc tgcccccagg caccagtccc    180
caggagctgt tcctgtttgg ggccaactgg accgtgcaca atgcgtcctc cctgctcacc    240
tacgattcct ggttcctggt ccacaacttc ctgtaccaac ccaagcacga ccccaccttc    300
gagcccctct tccccagtga gaccaccctc aaccccagcc tggcacaaga ggcagccaaa    360
ctatgtgggg acgatcattt ctgcaacttt gatgtggcag ccactgggag cctgagcacg    420
ggcactgcca ctcgggtggc ccaccagctg caccagcgtc gcatgcagag cctgcagcca    480
gtggtgtcct gtggctggct ggccccacct cccaacggac aaaaggaggg caacaggtac    540
ctggcgggtt ccaccatcta cttccactgt gacaacggct acagcctggc cggggcagag    600
accagcacct gccaggctga cggcacctgg tcctcaccca ccccgaagtg ccagccagga    660
cgcagctacg cggtgctgtt gggcatcatc tttgggggcc tcgcggtggt ggcggcggtt    720
gcgctcgtct atgtgctgct gcgccgcang aagggcaaca cgcacgtytg gggtgcacag    780
ccctgatggg agcagcttgg ctgtgagcac caggccaaga ctcctgagaa caggcagccc    840
agtcctgcga ctyccgcatc cccaggacca gacacctggg acctggatac ttgatacctg    900
ggcatttaac cccctactct gtcatctcag accccaggca ggaggcccag tgttccaaca    960
cccaagcccc gtgctagcag cgctccgtgc tcttccccaa atactcacgg ctctaattcc   1020
ccaaacctga aacttcatac cctgggattc taatacctat gtcctgagcc ctgacactcc   1080
cacacctgag cctcagattc caatagctca ctccctagag cctgacgccg gggcccctga   1140
cccctgagcc tcagattcca atacctcact ccccagagcc tgatgccggg gcccctgacc   1200
cctgatctac ggaggcctgc tcccggaccg tgcgggcacc agtgcagtgc tgccttggtt   1260
cctggacccc tgggcccatc ctgggacccc agatggggta aggagaggcc ccagaacccc   1320
aaagcagaca gcgagacccc cagcggcaga ggcctccctc ggcactccag gcttataatt   1380
tcgaactctt ctggaaggtc actcaggaac accctccctg cctgtgcaaa gagaaaacaa   1440
gcgccttgtt tccttmaaaa aaaaaaaaaa aaaaaaagat ttcgg                   1485

<210> 790
<211> 977
<212> DNA
<213> Homo sapiens

<400> 790
gcagattggg ccttgcgatg gatagcagat agaaaatcta cttttgggga aagagtggtg     60
gcctttgctg ctgtrgaagg agttttcytc tcrggatctt tkgckgctat attctggcta    120
aagaagagag gtcytatgcc aggactcact ttttccaatg aactcatcag cagagatgaa    180
ggacttcact gtgactttgc ttgcctgatg ttccaatact tagtaaataa gccttcagaa    240
gaaagggtca gggagatcat tgttgatgct gtcaaaattg agcaggagtt tttaacagaa    300
gccttgccag ttggcctcat tggmatgaat tgcattttga tgaaacagta cattgagttt    360
gtagctgaca gattactkgt ggracttgga ttctcaaagg tttttcaggc agaaaatcct    420
tttgatttta tggaaaacat ttctttagaa ggaaaaacaa atttctttga gaaacgagtt    480
tcagagtatc agcgttttgc agttatggca gaaaccacag ataacgtctt caccttggat    540
gcagattttt aaaaaacctc tcgttttaaa actctataaa cttgtcattg gtaaatagta    600
gtctattttc ctctgcttaa aaaaaatttt aagtatatcc tttaaaggac tgggggtttg    660
ctcaaaagga aatccaaaac ctattctaaa caatttgcat ttrtataatt ttcctgttta    720
acaacaagrg tgtgaccyaa akgcttttgt cttgtcactg aaataaaaga tggcattatg    780
tggttaagag catggggcga ggggtcagac atgagtctaa ggttctgccc ttactccagt    840
gtgtgaccct tggcaagtca gttaatcttg gtaaacctcg gtgtacttat ctttaaaatg    900
ggagtaatag taggtcctaa attcatagag tggatattag gattaggatg caaaaataaa    960
tgcttaacca acactaa                                                   977

<210> 791
<211> 1088
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (894)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1075)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1080)
<223> n equals a,t,g, or c

<400> 791
gtggacttat ctgcccagcc atgtggaaga aggaaggctc tcatgtagat gtctacgtgt     60
acatagcgcc tcaaagtgag gattatacac tacacatcaa ttcccctctg acgtcttagt    120
ggaaagtttc cattgagccc taatgctccc tagaagtatg tcacatcctg cccgcggagg    180
ggcccaccca gggccccatt ctggttaccc tcttcatgct cgaggttgtg ccctccaggt    240
gcatctcagc tcggagaggg gccctcaggg tcgcakcttg ctctgtccat catccagcat    300
ctgcctcctc actttgtgaa taacagggca catwgatatc ttcactggtg agatttgctg    360
gtggtaaaag catattatct ggctctcctt cctctcgctt cctctctcgc acctgagcgt    420
acgcacctgc ccgggcccgg ctccctcctc ctctcccctc cctctttccc cgcccggccg    480
cgggagcctc gtggctgcgt caccgccgcc cccccagaca agatggacac cgcggaggaa    540
gacatatgta gagtgtgtcg gtcagaagga acacctgaga aaccgcttta tcatccttgt    600
gtatgtactg gcagtattaa gtttatccat caagaatgct tagttcaatg gctgaaacac    660
agtcgaaaag aatactgtga attatgcaag cacagatttg cttttacacc aatttattct    720
ccagatatgc cttcacggct tccaattcaa gacatatttg ctggactggt tacaagtatt    780
ggcactgcaa tacgatattg gtttcattat acacttgtgg cctttgcatg gttgggagtt    840
gttcctctta cagcatgccg catctacaag tgcttgttta ctggctcccg tganctcact    900
gctgacggct gccattagat atgctgtcaa ccggaaaatt tgttggcaga ttgtttgcag    960
ggttggtttt tgtgggtgac gttgcacact gtgtgcaatt ccatccagcc ttgggtgtgg   1020
gttgaagaga gcagatagtc caatgggggg agcaccaaat ttgggttggg agcangctgn   1080
cccaccgg                                                            1088

<210> 792
<211> 670
<212> DNA
<213> Homo sapiens

<400> 792
gtaaagggtg catttggaat aattcaaaat aatctttctt atttgtccgt aaactctaac     60
ttatcttctt tcttcaactt ctaaacagag cagtctgaat gccagaatgg ataaccgttt    120
tgctacagca tttgtaattg cttgtgtgct tagcctcatt tccaccatct acatggcagc    180
ctccattggc acagacttct ggtatgaata tcgaagtcca gttcaagaaa attccagtga    240
tttgaataaa agcatctggg rtgaattcat tagtgatgag gcagatgraa agacttataa    300
tgrtgcactt tttcgrtaca atggcacagt gggattgtgg agacggtgtw tcaccatacc    360
caaaaacakg cattggtata gcccaccrga aaggrcmggt wtttctctta ttttaacttc    420
ygtcttcttc acctggttaa taatagacaa aacgacgtaa tgattgccca attacatgta    480
agcaggtttg ttggttctct ctctccttaa agaaataaat cgtgtatctt ctctttctac    540
tgccttctct ccccaacttc tttgcattac catggtactc atcaatattg gttggatgag    600
gaacttttct tatcttggga aagccttaat ggcttttttt ttttcttatt tactcactca    660
ttaaaataaa                                                           670

<210> 793
<211> 421
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (372)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (387)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (388)
<223> n equals a,t,g, or c

<400> 793
ggcacgagaa ggcctggaaa gagcccttcc tggttaaagt gccacttttn taggaaaaca     60
tttctgtgag catggcactg gatgcaaaca tttttaggcc cttttctttg ttgtggcttg    120
atctcactgc ctccttgggc tgctgtaaat ggcagtattt gctgcctgcc ctcctcccag    180
tgcagccctg acgctataag gaacagtgat gggcagagct ggggaaagac gcacagtaca    240
ctcttgtttc tgacttgcaa caaggaagca gtcaggcatt ttgtgtcttt gtggctctgg    300
atctgtgctt ttgcactaat ttttaaatat aggttttcat ttctcctact acagcagaat    360
ttgagcaata gnttctgggt aggaaannct aagactgtgt gtgtgtgtgt gtgtgtgtgt    420
g                                                                    421

<210> 794
<211> 440
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (284)
<223> n equals a,t,g, or c

<400> 794
gatatttatg ttgtttgtag aggatttcct atccccagga cctggccyag gctgagagaa     60
gctgtgtgga gtgsaagatg gacattgagg aagaagggca ggtgtggtct cacccagaat    120
ggttcctgct gcttccgcgg tgcccaggct tttctcacgg cctmtgmtgg gttctcccct    180
gggtgctgtg gatgcatcct gcctgctgga aattctgtgc tctctgtttc catccctttg    240
tcgtggtaat gaccgtatac ctctcccctg taccctcctc tgcntgctct ccgtgcaggc    300
ccctctccct ctggttgtcc catcagcatt tccccacagc tcgttgttcc tccttcctct    360
tttctggtga cctttctact gattgcattg tacctctttc cctgatatta aagatgtttt    420
taacgactac aaaaaaaaaa                                                440

<210> 795
<211> 2665
<212> DNA
<213> Homo sapiens

<400> 795
ggcacgaggc ccttgtcccc cacgacggcc acgtccccct atggaggggg ccacgccctt     60
gccggtcaaa cttcacccaa gcaggagaat gggaccttgg ctctacttcc aggggccccc    120
gacccttccc agcctctgtk ttgaggttgc cgggggtagg ggtggggcca cacaaatytc    180
caggagccac cactcaacay aatggccctg cctcccaccg ctttatttct ttcggtttcg    240
gatgcaaaac aaaaaatttt aaaagaaaat gtgacttcaa aggaaaagaa caaatttcca    300
aagacttggg ggagtgaagg cagagcctgg tgcagatgga cgaggtctgc agacggaggg    360
cagaggtggt ggaaggggcc aggggctgca ggcctccccc tggaactggg actggtctcg    420
gtctgctgac gtcagggtca gctcccccgc ggagctgact tcagcagccc acagctgtgg    480
ggcttcagca gccacaccag cccagcccag cccagctctc gatacgtttg gtctttcatg    540
ctgaaaaata aataataaag cctgtcccgt gtctactgcc tcccccaact gcacagacgc    600
cagcctctag gcctgactgc cagggaggtg gaaacactgg ccaccagccc ggcagcccct    660
acaggccccc cagatgggct gcctcagtcg tcctctgaga gctgcagatc ctccagctcg    720
tcctccggcc cctgggccag ctgctgcagc tccccagggg ccagccccgc ctctgcgtct    780
gggtctccat cccaagacca ttcaccctcc gagttgctgc tgtcctcctc gccctcctcc    840
tcgtcctctt catcgtcttc caccccatgc cgagtgctca ggggcctcag tatccctctc    900
tccgagaatc cctcggtgtc gtcctcttca gagctgttca ggtcaaagag gtctttaaat    960
tgcttcctgt cctcatcctt cctgtcagcc atcttccttc gtttgatctc agggaagttc   1020
aggtcttcca gccgctcttt gccactgatc tccagctgga tctcccggtc acgcagcttg   1080
cgccagtggc tgtagtacaa ggtcargggt gtcccctctt cccgggtcag cttctcccag   1140
gcttccactg cctgctgctc agagacgccg aaggaaaccc tctggcggcg gctgcagatg   1200
tatgccgagt tctcctgaac cttcccaagc agctgctgca cctgccggca gtagttggcc   1260
accttgcact cccggaggaa cgacttcagc tgcaggacca caggcagcac cagctccggg   1320
aagccgatgc agtgtgcctg gctgtgcagg tactccaggg tgaggtcgta cagctgctcc   1380
accaggccgt cccggtacgc cttctcctgc aggttgacat tggacagctt caggatcacg   1440
gagaagttga tgggcttgga gctcatgcgc cctggcttcc tgttgaagtc gacctgctgg   1500
aacatctcca ggatgaaagg cagcaccggg atgaaggccc ccgagctccc cgagagcagc   1560
gtcagggcac ggatgcagtg cattcgcagc gggtagaagc gggcagtggg gatgagcttg   1620
atacagccaa tgatgacttg ggcaaggggg tagaccaagg gctggaggst tcgctggggc   1680
ccgcagtgct caggacccgg caccacagga agaggcagtg cacatactgc cagttgtaca   1740
cagactggta tgtttccttc ttgcgggtgg tcatggcgtt gcgcaggtgt atggcgagct   1800
ggcggatgta gaggaaggcg tgctggtagg ccacacccgg ctccagggcc agcagctccg   1860
tcaaggtcca ctgcatgaaa ctgatgaagg ggagggcacc aggcgaggtg aacttgcagt   1920
tcctcacata cgtgatgtac atttgcttga ggacggggcc aaggaaagtg tccttcttgt   1980
gccggcagac tctgctgagg accaggaaag ccagcacccg cagagactcc tccccagtgc   2040
tccatacgac caccattctc ttgagcagca tgcggcactg cttggggaag gtcaggaagc   2100
agggcaccag cacgctgatg tgccgcagca cggccgccaa caccgtcgtc tccgacagac   2160
aggacaccag ctgtatggcc gagcccaggt aagccttgat gtccacacga agcttccccc   2220
agagcgggct gctggacggc tgcagcatcc tgctgctatc ctttgccacc tttccaaaca   2280
gcagcttctg gagacagcca atgaggtctc tgatgcagaa ggtaaccaga gcattgaatg   2340
cagcactgtc cgtgacctgg aatttgttgg cctcagcact ttcctggtcc cctcgggtgg   2400
tggccacagc tgctcggaac gcctgtacca cttcatggaa cagctttgga gtgaggcgtt   2460
gctttgctgc ctgcttccat ctctcaacca tggcgacggt cacaggaaca gaattcttct   2520
tccccttcag ccctctgggg actctgtccc catcttctcc ttcctccgct ccatcctcct   2580
cctcactggc ttcctccagc acatctggca gggagtggaa cggcccctct tcctcctcag   2640
agctgtccga gtcgctgaag tttac                                         2665

<210> 796
<211> 644
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (569)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (600)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (627)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (632)
<223> n equals a,t,g, or c

<400> 796
ggcacgaggg caccatctgc ggaatcggcc ggatctgtat ggccccttct ggatctgtgc     60
cacgttggcc tttgtcctgg ccgtcactgg caacctgacg ctggtgctgg cccagaggag    120
ggacccctcc atccactaca gcccccagtt ccacaaggtg accgtggcag gcatcagcat    180
ctactgctat gcgtggctgg tgcccctggc cctgtggggc ttcctgcggt ggcgcaaggg    240
tgtccaggag cgcatggggc cctacacctt cctggagact gtgtgcatct acggctactc    300
cctctttgtc ttcatcccca tggtggtcct gtggctcatc cctgtgcctt ggctggcagt    360
ggctctttgg ggcgctggcc ctgggmctgt cagccgccgg gctggtattc accctctggc    420
ccgtggtccg tgaggacacc aggctggtgg ccacagtgct gctgtccgtg gtcgtgctgc    480
tccacgccct cctggccatg gggctgtaag ttgtattctt ccagtcgctg cctccggaga    540
acgtggctct ccaacccaaa atcacattnt ggcctcaaaa aatcggggtg ttccctaacn    600
tgcggaattc cttggcccct tctaagnaag gnccggggtt ccaa                     644

<210> 797
<211> 1633
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1599)
<223> n equals a,t,g, or c

<400> 797
aattcggcag agcatagtct ttcaaatttg gacatttaaa aaagaaactt ttactgtagt     60
catgaagtag tatcaaagtt taccacaagt ttgtattgag agaagaacaa acaatatatg    120
ctaatatgaa aaacagctct acttagaaag ctactgcttg ggttttctta ttaggcatag    180
ttctccagac tgagttggtt ttactcatct acatgatttt tccttgcctt atggaacaga    240
aattcaggcc cactcgaatt cagttatttt agggctcttt aaaatccagt atttgtgatt    300
taaatgatgc ggagggactt tcattacctg tgtctttgct tatttctctc tggccctcag    360
aacaccccac cctgaccttt aggggaaatt gacagaggca gagggtttca cctgcctcaa    420
ttgtcaccag ccctgttaca ttcttccttc caagccttag cctcacaggg accttctcat    480
tattgaacaa wtgccttcaa agcagtagaa tagcccaatt gttatggaga ttaaagatac    540
cgattgcaaa actcctgtaa ataaaatctt cactgacaaa cccagtttct tttcataggc    600
ttttcttctg taatctcttt ctggcagaac atctcatgtt ttgatgttag agattcagtt    660
accaaccaca gtaaataaag caaaataata atagaaaaat agtatagaac tcaccctaaa    720
aacaaacatt ggccaaccat gtttattttt tgtctctctt tgcactcctg agaattgata    780
ggggaagaat gtaccacctc taattcaggt gatttctgat tagcaagcta tggaaagtct    840
tcaggttgag ttttagccag ttcacgctcc cctaaatggc atggaataga ctattttctg    900
ttttaagaaa aaatagaaca atggcactaa atgcttgact gaatgtttga ctaaatgttg    960
actgaatcat ggataggaaa gattgggcag aaaagacagc cactgcctcc agacacagga   1020
tgccacaatc ctgggcacca tcattattcc atacaacctt agggtcattt ttagggttta   1080
gaactttctc aatagggttt caagattttg aaaagtgtct tccaattctg atctccgtag   1140
atcctgttat gggaattaac ctttttggaa ggggattctt gttcttaaag atgaaattcc   1200
ctactttctt tcctggaggg aatcagtatg ggcagaggga agaggagatg gcgattctga   1260
cctgtgtgtc tcatgtcacc taacacctat ggggtggcat gaaacttgag ctttaaaaca   1320
caccaggggc caggcacagt ggctcatgct ggtaatccca gcactttggg agaccgaggt   1380
gggtggatca cctgaggtca ggagttcgag accagcctgc caacatggca aaaccccgtc   1440
tctactaaaa atacaaaaat cagctgggtg tggtggcggg cacctgtaat cccagctact   1500
tgggaggctg aggcaggaga atcgcttgaa cctgggaggc agaggttgca gtgagccgag   1560
atcaggccat tgtactctag cctgggtgac aagagtgana ctccatctga aaaaaaaaaa   1620
aaaaaaactc gag                                                      1633

<210> 798
<211> 1140
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (179)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (182)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (978)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1078)
<223> n equals a,t,g, or c

<400> 798
gacgcagact catgcacgca cacaggagga ctgaagacct gaaggggctg gcttttggag     60
tgttgaggtc aacgtggagg taccaggcca ccatgctcag tctcaagctg ccccaacttc    120
ttcaagtcca ccaggtcccc cgggtgttct gggaagatgg catcatgtct ggctaccgnc    180
gncccaccaa gctcggcttt tggactgtgt cctcaagctc cttcagatga scaacgagac    240
ggtcaamatc tggactcact tctgcccacc tggtacttcc tgtggcggct cctggcgctg    300
gcggcggccc ggcttccgtg cggagccgta ccactggccg ctgctggtct tcctgctgcc    360
cgcctgcctc taccccttcg cgtcgtgctg cgcgcacacc ttcagctcca tgtcgccccg    420
catgcgccac atctgctact tcctcgacta cggcgcgctc agcctctaca gtctggtttc    480
ctggagctgg aaagccctgg gctcagtaag gtcctccgca caggagcctt cgcctatcca    540
ttcctgttcg acaacctccc actcttttat cggctcgggc tgtgctgggg caggggccac    600
ggctgtgggc aggaggccct gagcaccagc catggctacc atctcttctg cgcgctgctc    660
actggcttcc tcttcgcctc ccacctgcct gaaagctggc accaggacgc tttgattaca    720
tcggccacag ccaccagtta ttccacatct gtgcagtgct gggcacccac ttccagctgg    780
aggcagtgct ggctgatatg ggatcacgca gagcctggct ggccacacag gaacctgccc    840
tgggcctggc aggcacagtg gccacactgg tcttggctgc agctgggaac tactcattat    900
tgctgctttc acagccaacc tgcttcgggc ccccagtaca tgccctctgc tgcaaggtgg    960
cccactggag gggggtancc aggccaaaca acagtgaggc cccatccctg aaccctgtcc   1020
tggagggggc araggcmagg ccccagtgct gacggaggag cccagatttg ggcctaantc   1080
aggtggggga cgcatcttag cctggtaacc aacagggggc tttaggagag agggcacagg   1140

<210> 799
<211> 1452
<212> DNA
<213> Homo sapiens

<400> 799
gcccacgcgt ccgggcgtag aaagtgcttc ctggagcgca gacgaggtca tgaatcatgt     60
gacggtggct tgaggaggaa cctgtcttta aagctgtccc tgaagtgaca gcggagagaa    120
ccaggcagcc cagaaacccc aggcgtggag attgatcctg cgagagaagg gggttcatca    180
tggcggatga cctaaagcga ttcttgtata aaaagttacc aagtgttgaa gggctccatg    240
ccattgttgt gtcagataga gatggagtac ctgttattaa agtggcaaat gacaatgctc    300
cagagcatgc tttgcgacct ggtttcttat ccacttttgc ccttgcaaca gaccaaggaa    360
gcaaacttgg actttccaaa aataaaagta tcatctgtta ctataacacc taccaggtgg    420
ttcaatttaa tcgtttacct ttggtggtga gtttcatagc cagcagcagt gccaatacag    480
gactaattgt cagcctagaa aaggaacttg ctccattgtt tgaagaactg agacaagttg    540
tggaagtttc ttaatctgac agtggtttca gtgtgtacct tatcttcatt ataacaacac    600
aatatcaatc cagcaatctt tagactacaa taatactttt atccatgtgc tcaagaaagg    660
gccccttttt ccaacttata ctaaagagct agcatataga tgtaatttat agatagatca    720
gttgctatat tttctggtgt agggtctttc ttatttagtg agatctaggg ataccacaga    780
aatggttcag tctatcacag ctcccatgga gttagtctgg tcaccagata tggatgagag    840
attctattca gtggatcaga atcaaactgg tacattgatc cacttgagcc gttaagtgct    900
gccaattgta caatatgccc aggcttgcag aataaagcca actttttatt gtgaataata    960
ataaggacat atttttcttc agattatgtt ttatttcttt gcattgagtg aggaacataa   1020
aatggcttgg taaaagtaat aaaatcagta caatcactaa ctttcctttg tacatattat   1080
tttgcagtat agatgaatat tactaatcag tttgattatt ctcagagggt gctgctcttt   1140
aatgaaaatg aaaattatag ctaatgtttt ttcctcaaac tctgctttct gtaaccaatc   1200
agtgttttaa tgtttgtgtg ttcttcataa aatttaaata caattcgtta ttctgtttcc   1260
aatgttagta tgtatgtaaa catgatagta cagccatttt tttcatatgt gagtaaaaat   1320
aaaatagtat ttttaaaaat atagtttgag cactgtatag gtcctttttt tgttcagact   1380
ttttccaaaa atctaaacat aattaatata ctctttcagc cacatgaata aataatgagt   1440
gtttcttgta aa                                                       1452

<210> 800
<211> 882
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (820)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (829)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (843)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (856)
<223> n equals a,t,g, or c

<400> 800
gcttggtttt ctctcattat gccttttgca acggttatct tttttgtcat gatcctggat     60
ttctacgtgg attccatttg ttcagtcaaa atggaagttt ccaaatgtgc tcgttatgga    120
tcctttccca tttttattag tgctctcctt tttggaaatt tttggacaca tccaataaca    180
gaccagcttc gggctatgaa caaagcagca caccaggaga gcactgaaca cgtcctgtct    240
ggaggagtgg tagtgagtgc tatattcttc attttgtctg ccaatatctt atcatctccc    300
tctaagagag gacaaaaagg tacccttatt ggatattctc ctgaaggaac acctctttat    360
aacttcatgg gtgatgcttt tcagcatagc tctcaatcga tccctaggtt tattaaggaa    420
tcactaaaac aaattcttga ggagagtgac tctaggcaga tcttttactt cttgtgcttg    480
aatctgcttt ttacctttgt ggaattattc tatggcgtgc tgaccaatag tctgggcctg    540
atctcggatg gattccacat gctttttgac tgctctgctt tagtcatggg actttttgct    600
gccctgatga gtaggtggaa agccactcgg attttctcct atgggtacgg ccgaatagaa    660
attctgtctg gatttattaa tggacttttt ctaatagtaa tagcgttttt tgtgtttatg    720
ggagtcagtg gctagattga ttgatcctcc agaattakac actcacatgt taacaccagt    780
ctcagttggg aggggctgat agttaaacct tattgggtan ctgtggccnt tagccatgcc    840
ccntaggcca tgcccnggga gcttctcaag ggaaggtgtt ca                       882

<210> 801
<211> 817
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (802)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (803)
<223> n equals a,t,g, or c

<400> 801
ggcacaggcc aggtcgtgcc agcatccgcc ggacgccgga agtggttctc cgcccctgcc     60
actgggccat ggagactgtg gcacagtaga ctgtagtgtg aggctcgcgg gggcagtggc    120
catggaggcc gtgctgaacg agctggtgtc tgtggaggac ctgctgaagt ttgaaaagaa    180
atttcagtct gagaaggcag caggctcggt gtccaagagc acgcagtttg agtacgcctg    240
gtgcctggtg cggagcaagt acaatgatga catccgtaaa ggcatcgtgc tgctcgagga    300
gctgctgccc aaagggagca aggaggaaca gcgggattac gtcttctacc tggccgtggg    360
gaactaccgg ctcaaggaat acgagaaggc cttaaagtac gtccgcgggt tgctgcagac    420
agagccccag aacaaccagg ccaaggaact ggagcggctc attgacaagg ccatgaagaa    480
agatggactc gtgggcatgg ccatcgtggg aggcatggcc ctgggtgtgg cgggactggc    540
cggactcatc ggacttgctg tgtccaagtc caaatcctga aggagacgcg ggagcccacg    600
gagaacgctc caggagggcc tgtccatcct cgctgtcctt tccctgttct ccccctgccc    660
cccgtctcta tcctctgtgg ccttcagcta atttctgctc ccctgagatt cgtccttcag    720
ccccatcatg tgctttggga tgagtgtaaa taaaacgggg ctgtggcttg ggaaaaaaaa    780
aaaaaaaaaa aaaaaaaaaa annaaaaaag ggggggg                             817

<210> 802
<211> 890
<212> DNA
<213> Homo sapiens

<400> 802
tctagaacta gtggatcccc cgggctgcag gaattcggca cgagcggcgg cggtggcctt     60
tggggccgaa gtgggcgtgc ggctcgcgct gttcgcggcc ttcctggtga cggagctgct    120
ccccccgttc cagagactca tccagccgga ggagatgtgg ctctaccgga acccctacgt    180
ggaggcggag tatttcccca ccaagccgat gtttgttatt gcatttctct ctccactgtc    240
tctgatcttc ctggccaaat ttctcaagaa ggcagacaca agagacagca gacaagcctg    300
cctggctgcc agccttgccc tggctctgaa tggcgtcttt accaacacaa taaaactgat    360
cgtagggagc atttcccacc aacggccaca gcagtcggtc agtgtcctct tgagcacctt    420
cctgaagctg cagtgtcatt tgctgtttgc cctaaaaagc cacgcccaga tttcttctac    480
cgctgcttcc ctgatgggct agcccattct gacttgatgt gtacagggga taaggacgtg    540
gtgaatgagg gccgaaagag cttccccagt ggacattctt cctgtatgaa tatcatatgg    600
actctaccct atgcttgttt tcacatcatt gaatttaacc tagaaagcta gtagggatgg    660
gaaaatctga ctactcttgt ttctacaatt tggaaaatcc ccccttcttt agtaactcca    720
cagtttaaca agtctgagcc ttgactattt gggtaaatat tacagaacag aaaggtagtt    780
taccttcatg agatttgcac atttaattgt tatattattt gcctagatcc tgcaatcttg    840
tactagcaat aaaaatacct ttaacgaaga aaaaaaaaaa aaaaaaaaaa               890

<210> 803
<211> 1071
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1033)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1053)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1057)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1070)
<223> n equals a,t,g, or c

<400> 803
gatgaatttc agcatatttc ttcaagaaat gtctcttttt aaacagcaga gccctggcaa     60
gttttgtctc ctggtctgca gtgtgtgcac attttttacg atcttgggaa gttacattcc    120
tggggttata ctcagctatc tactgttact gtgtgcattt ttgtgtccat tgtttaaatg    180
taatgatatt ggacaaaaaa tttacagcaa aattaagtca gttctgctga aactggattt    240
tggaattgga gaatatatta atcagaagaa acgtgagaga tctgaagcag ayaaagaaaa    300
aagtcacaaa gatgacagtg aattagactt ttcarctctt tgtcctaaga ttagcctcac    360
ggttgctgcc aaagagttat ctgtgtctga cacagacgtc tcagaggtat cctggactga    420
taatgggacc ttcaaccttt cagaaggata cactccacag acagacactt ctgatgatct    480
tgaccgaccc agtgaggaag ttttctctag agatctttca gattttccat ctctagaaaa    540
tggcatggga acaaatgatg aagatgaatt aagccttggt ttgcccactg agctcaagag    600
aaagaaggaa cagttggaca gtggtcacag accaagcaaa gagacgcaat cagcagctgg    660
tctcaccctt cctctgaaca gtgaccaaac ctttcacctg atgagcaacc tggctgggga    720
tgttatcaca gctgcagtga ctgcagctat caaagaccag ttagagggtg tgcagcaagc    780
actttctcag gctgccccca tcccagaaga ggacacagac actgaagaag gtgatgactt    840
tgaactactt gaccagtcag agctggatca aattgagagt gaattgggac ttacacaaga    900
ccaggaagca gaagcacagc aaaataagaa gtcttcaggt ttcctttcaa atctgctggg    960
aggccattaa tctaggaatc agcttgcaac agagcacaaa aaacaccaaa aaaatttcaa   1020
acmmgaaaaa aanaaaaaaa aaaagggggg ggncccnttt ttaaaggggn t            1071

<210> 804
<211> 778
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (754)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (763)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (766)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (770)
<223> n equals a,t,g, or c

<400> 804
gcggccgcgg taacctggct gctcggggag ccggtgctgt ggctgggctg ccgcgccgac     60
gagctgctga gctggaagag gccgctgcgg agcctgctcg gcttcgtcgc tgccaacctg    120
ctgttctggt tccttgcatt gactccatgg agagtatatc acctgatttc cgtcatgata    180
cttgggcgtg ttattatgca aataataaag gatatggttt tgtctagaac aagaggtgca    240
cagttgtgga gaagcctcag tgaaagctgg gaagttatca attccaaacc agatgaaaga    300
cccaggctca gccactgtat tgcagaatca tggatgaatt tcagcatatt tcttcaagaa    360
atgtctcttt ttaaacagca gagccctggc aagttttgtc tcctggtctg tagtgtgtgc    420
acatttttta cgatcttggg aagttacatt cctggggtta tactcagcta tctactgtta    480
ctgtgtgcat ttttgtgtcc attgtttaaa tgtaatgata ttggacaaaa aatttacagc    540
aaaattaagt cagttctgct gaaactggat tttggaattg gagaatatat taatcagaag    600
aaacgtgaga gatctgaagc agataaagaa aaaagtcmca aagatgacag tgaattaact    660
ttccactctt tgtcctaara tacctcacgg ttgtgccaaa rttactgttc tgaccaactc    720
cccaagttac ctgacgatat ggactccacc ttcnaaggaa ccnccncaan aactccta      778

<210> 805
<211> 594
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (552)
<223> n equals a,t,g, or c

<400> 805
ctgcaggacc atgatggatc ctcggccctc atgctggcct gtcaccatgg caacgtggac     60
ctggtgcggc tgctcctggc acacccagcc tgckacagca gcctgactga caaggctggc    120
cgcacagctt tgtccatcgc tctgaagtca cccacccata tggaaattgc tgggcttctg    180
agagcccacg cggacagggc aggtccctgg ggctgtaggg gctgcagaag aactggccgt    240
ggggaacaaa agccttcttc tctggactcc tccctcgccc ttgaagaggg cagaggtcac    300
aggccagaga gccacccttc tagagaagaa actatgtcaa atatgcacat acattcctgt    360
tgtataattc tgctcattag gatgctttgt agtttttgcc ttaggccaag cctgaaaact    420
acacgggctt cagagcaggg ttcaagtgca agtgaagggt acgtcgtgtc atccaaacat    480
ccaaaacatc ttcagccttg aattcctcat gactctaacc tctgtaacat tgtgtagcaa    540
gcaagcaagc angagcacat tagcacatag aaaagcaata ctttttacat ggaa          594

<210> 806
<211> 1686
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1652)
<223> n equals a,t,g, or c

<400> 806
gagggtctct gcggccgtag cggccggggc tgcggtagcc actttagatt tgggcaagga     60
ctttagattc gggctctgtt ctgtttccgc cgtcctgctt cctgccgagg ctggcccagg    120
cagccgcgct tcgaaggacg ccgccgggag ctgcggagca tgcgtggagt ggcagtgcta    180
acggctggtg tctcgcactg ttggcctgtg aaggtacgtg aagctgaaag cctggaatgg    240
ctggaaaggg gtcatcaggc aggcggcccc tgctgctggg gctgctggtg gccgtagcca    300
ctgtccacct ggtcatctgt ccctacacca aagtggagga gagcttcaac ctgcaggcca    360
cacatgacct gctctaccac tggcaagacc tggagcagta cgaccatctt gagttccccg    420
gagtcgtccc caggacgttc ctcgggccag tggtgatcgc agtgttctcc agccccgcgg    480
tttacgtgct ttcgctgtta gaaatgtcca agttttactc tcagctaata gttagaggag    540
tgcttggact cggcgtgatt tttggactct ggacgttaca aaaggaagtg agacggcact    600
tcggggccat ggtggccacc atgttctgct gggtgacggc catgcagttc cacctgatgt    660
tctactgcac gcggacactg cccaatgtgc tggccctgcc tgtagtcctg ctggccctcg    720
cggcctggct gcggcacgag tgggcccgct tcatctggct gtcagccttc gccatcatcg    780
tgttcagggt ggagctgtgc ctgttcctgg gcctcctgct gctgctggcc ttgggcaacc    840
gaaaggtttc tgtagtcaga gcccttcgcc acgccgtccc ggcagggatc ctctgtttag    900
gactgacggt tgctgtggac tcttattttt ggcggcagct cacttggccg gaaggaaagg    960
tgctttggta caacactgtc ctgaacaaaa gctccaactg ggggacctcc ccgctgctgt   1020
ggtacttcta ctcagccctg ccccgcggcc tgggctgcag cctgctcttc atccccctgg   1080
gcttggtaga cagaaggacg cacgcgccga cggtgctggc actgggcttc atggcactct   1140
actccctcct gccacacaag gagctacgct tcatcatcta tgccttcccc atgctcaaca   1200
tcacggctgc cagaggctgc tcctacctgc tgaataacta taaaaagtct tggctgtaca   1260
aagcggggtc tctgcttgtg atcggacacc tcgtggtgaa tgccgcctac tcagccacgg   1320
ccctgtatgt gtcccatttc aactacccag gtggcgtcgc aatgcagagg ctgcaccagc   1380
tggtgccccc ccagacagac gtccttctgc acattgacgt ggcagccgcc cagacaggtg   1440
tgtctcggtt tctccaagtc aacagcgcct ggaggtacga caagagggag gatgtgcagc   1500
cggggacagg catgctggca tacacacaca tcctcatgga ggcggcccct gggctcctgg   1560
ccctctacag ggacacacac cgggtcctgg ccagcgtcgt ggggaccaca ggtgtgartc   1620
tgaacctgrc ccaamtkgcc cccttcaacg tncacctgca gacaaagctg gtgcttttgg   1680
gaaagg                                                              1686

<210> 807
<211> 554
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (361)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (416)
<223> n equals a,t,g, or c

<400> 807
cttggtgaga gaagaagccc agaaaatgag tagtctttta ccaactatgt ggcttggagc     60
tcaaaatggc tgtttgtatg tccattcatc tgtagcccag tggaggaaat gtctccattc    120
cattaaactt aaagattcga ttctcagtat tgtacacgtg aagggaatcg tgttagtagc    180
cctggctgac ggcacccttg caatctttca cagaggagtg gatgggcagt gggatttgtc    240
aaactatcac ctcttagacc ttggacggcc tcatcattcc atccgttgca tgactgtggt    300
acatgacaaa gtctggtgtg gctataggar caaaatctat gtggtgcagc caaaggccat    360
ngaaaataga gaaatctttt gatgcacatc ccaggaagga gagccaagtg cgacanttgc    420
gtgggtgggg gatggcgtgt gggtctccat tcgcttggga ttctacggtc cgtctctatc    480
atggcacaca cttattcaac atctacagga tttgggacat tgagccttat gtaagcaaaa    540
tgtttaggta ctgg                                                      554

<210> 808
<211> 1510
<212> DNA
<213> Homo sapiens

<400> 808
gagccgggac cgtgccattg tactccagcc tgggtgacag agcgagattc cgtctcaaaa     60
aaaaaaaaaa aaagcccacc tgaaagcctg tctctttcca ctttgttggc ccttccagtg    120
ggattatcga gcatgttgtt ttttcatagt gcctttttcc ttatttcaag ggttgcttct    180
gagtggtgtt tttttttttt ttaatttgtt ttgttttaaa ataagttaaa grcagtccag    240
agcttttcag ccaatttgtc tcctactctg tgtaaatatt tttccctccg ggcaggggag    300
ccagggtaga gcaaaggaga caagcaggag tggaaggtga ggcgttctcc tgcttgtact    360
aagccaggag gctttaagct ccagctttaa gggttgtgag ccccttgggg gttcagggaa    420
ctgcttgccc agggtgcagt gtgagtgtga tgggccaccg gggcaagagg gaaggtgacc    480
gcccagctct cccacatccc actggatctg gcttacaggg gggtcggaag cctgtcctca    540
ccgtctcggg ggttgtggcc cccgccccct ccctatatgc acccctggaa ccagcaagtc    600
ccagacaagg agagcggagg aggaagtcat gggaacgcag cctccagttg tagcaggttt    660
cactattcct atgctggggt acacagtgag agtactcact tttcacttgt cttgctctta    720
gattgggcca tggctttcat cctgtgtccc ctgacctgtc caggtgagtg tgagggcagc    780
actgggaagc tggagtgctg cttgtgcctc ccttcccagt gggctgtgtt gactgctgct    840
ccccacccct accgatggtc ccaggaagca gggagagttg gggaaggcaa gattggaaag    900
acaggaagac caaggcctcg gcagaactct ctgtcttctc tccacttctg gtcccctgtg    960
gtgatgtgcc tgtaatcttt ttctccaccc aaaccccttc ccacgacaaa aacaagactg   1020
cctccctctc ttccgggagc tggtgacagc cttgggcctt tcagtcccaa agcggccgat   1080
gggagtctcc ctccgactcc agatatgaac agggcccagg cctggagcgt ttgctgtgcc   1140
aggaggcggc agctcttctg ggcagagcct gtccccgcct tccctcactc ttcctcatcc   1200
tgcttctctt ttcctcgcag atgataaaag gaatctggca ttctacacct ggaccatttg   1260
attgttttat tttggaattg gtgtatatca tgaagccttg ctgaactaag ttttgtgtgt   1320
atatatttaa aaaaaaaatc agtgtttaaa taaagaccta tgtacttaat cctttaactc   1380
tgcggatagc atttggtagg tagtgattaa ctgtgaataa taaatacaca atgaattctt   1440
maaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaccccg gggggggccc cgggccccaa   1500
ttccccccaa                                                          1510

<210> 809
<211> 2044
<212> DNA
<213> Homo sapiens

<400> 809
gtcatgcagt gcgccggaga actgtgctct ttgaggccga cgctaggggc ccggaaggga     60
aactgcgagg cgaaggtgac cggggaccga gcatttcaga tctgctcggt agacctggtg    120
caccaccacc atgttggctg caaggctggt gtgtctccgg acactacctt ctagggtttt    180
ccacccagct ttcaccaagg cctcccctgt tgtgaagaat tccatcacga agaatcaatg    240
gctgttaaca cctagcaggg aatatgccac caaaacaaga attgggatcc ggcgtgggag    300
aactggccaa gaactcaaag aggcagcatt ggaaccatcg atggaaaaaa tatttaaaat    360
tgatcagatg ggaagatggt ttgttgctgg aggggctgct gttggtcttg gagcattgtg    420
ctactatggc ttgggactgt ctaatgagat tggagctatt gaaaaggctg taatttggcc    480
tcagtatgtc aaggatagaa ttcattccac ctatatgtac ttagcaggga gtattggttt    540
aacagctttg tctgccatag caatcagcag aacgcctgtt ctcatgaact tcatgatgag    600
aggctcttgg gtgacaattg gtgtgacctt tgcagccatg gttggagctg gaatgctggt    660
acgatcaata ccatatgacc agagcccagg cccaaagcat cttgcttggt tgctacattc    720
tggtgtgatg ggtgcagtgg tggctcctct gacaatatta gggggtcctc ttctcatcag    780
agctgcatgg tacacagctg gcattgtggg aggcctctcc actgtggcca tgtgtgcgcc    840
cagtgaaaag tttctgaaca tgggtgcacc cctgggagtg ggcctgggtc tcgtctttgt    900
gtcctcattg ggatctatgt ttcttccacc taccaccgtg gctggtgcca ctctttactc    960
agtggcaatg tacggtggat tagttctttt cagcatgttc cttctgtatg atacccagaa   1020
agtaatcaag cgtgcagaag tatcaccaat gtatggagtt caaaaatatg atcccattaa   1080
ctcgatgctg agtatctaca tggatacatt aaatatattt atgcgagttg caactatgct   1140
ggcaactgga ggcaacagaa agaaatgaag tgactcagct tctggcttct ctgctacatc   1200
aaatatcttg tttaatgggg cagatatgca ttaaatagtt tgtacaagca gctttcgttg   1260
aagtttagaa gataagaaac atgtcatcat atttaaatgt tccggtaatg tgatgcctca   1320
ggtctgcctt tttttctgga gaataaatgc agtaatcctc tcccaaataa gcacacacat   1380
tttcaattct catgtttgag tgattttaaa atgttttggt gaatgtgaaa actaaagttt   1440
gtgtcatgag aatgtaagtc ttttttctac tttaaaattt agtaggttca ctgagtaact   1500
aaaatttagc aaacctgtgt ttgcatattt ttttggagtg cagaatattg taattaatgt   1560
cataagtgat ttggagcttt ggtaaaggga ccagagagaa ggagtcacct gcagtctttt   1620
gtttttttaa atacttagaa cttagcactt gtgttattga ttagtgagga gccagtaaga   1680
aacatctggg tatttggaaa caagtggtca ttgttacatt catctgctga acttaacaaa   1740
actgttcatc ctgaaacagg cacaggtgat gcattctcct gctgttgctt ctcagtgctc   1800
tctttccaat atagatgtgg tcatgtttga cttgtacaga atgttaatca tacagagaat   1860
ccttgatgga attatatatg tgtgttttac ttttgaatgt tacaaaagga aataacttta   1920
aaactattct caagagaaaa tattcaaagc atgaaatatg ttgctttttc cagaatacaa   1980
acagtatact catgaaaaaa aaaaaaaagg gcggccgctc tagaggatcc ctcgaggggc   2040
ccaa                                                                2044

<210> 810
<211> 482
<212> DNA
<213> Homo sapiens

<400> 810
agcacaacta tgttggtgga gaagtctctg agtgtcattt tgcttgttgt agctctggct     60
atgctgatta ttgatctgag aatgaaatct ttcttagcta ttccaaactt agttattttt    120
gcagttttgt tatttttttc ctcattggaa actcccaaaa atccgattgc ttttgcgtgt    180
ttttttattt gcctgataac tgatcctttc cttgacattt attttagtgg actttcagta    240
actgaaagat ggaaaccctt tttgtaccgt ggaagaattt gcagaagact tycagtcgtt    300
tttgctggaa tgattgagct tacatttttt attctttccg cattcaaact tagagacact    360
cacctctggt attttgtaat acctggcttt tccatttttg gaattttctg gatgatttgt    420
catattattt tcttttaact ctttggggat ccataccaaa ttaaatgact gccataaagt    480
aa                                                                   482

<210> 811
<211> 845
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (514)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (758)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (800)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (822)
<223> n equals a,t,g, or c

<400> 811
gaacaactgt ggtgaaactg agcaagacac agagaaaatg aaaaaaatcc tggaagtggt     60
taaccaaatc caggatgaag aacgaatggt acaatctcaa aagagttcta gtcccctttc    120
tagcaccagg agcaagaggt ctactctgtt gcctccagag gcatctgagg gaagtagtag    180
ctttttggga aaactcatgg gcttcattgc taccccattc atcaagcttt ttcaattaat    240
ttattacctt atggtagcaa tcctgaagaa cattgtctat ttcctgtggt gtgttaccaa    300
gcaggtgatt aatggcatag aaagttgcct ttaccgcctg ggctcagcca ccatctcata    360
cttcatggcc attggggaag agttggtgag cattccctgg aaggkgctca aggtcgtggc    420
cmaagtcatc agggctctyc tccggatcct ttgttgtctg ctgaargcca tttgccgagt    480
tytgagcatc cctgtccgwg tccttgtgga tgtngccact ttccctgtgt acaccatggk    540
cgctattcca attgtttgca aggacattgc actgggcctt ggtggcactg tctcactgct    600
ctttgacact gcttttggta ccctgggtgg cctatttcag gtggttttta gtgtctgcaa    660
gcggattggc tacaaggtta cttttgacaa ttctggggga gttataaact caaaaaacta    720
atagtatcca gtcacagtga atttgaaagc tggaatantt tgtctttgac aatgggtttc    780
tgttcactgt cattgagcan gagatttggc cttggtgggg angtctgctt gtttttggca    840
aaaaa                                                                845

<210> 812
<211> 1188
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (539)
<223> n equals a,t,g, or c

<400> 812
cggacgcgtg ggcggacgcg tgggcggaat ctacaccttc ccggccagcg gtacaactgc     60
agaactgcag gagactatct ttctagacaa ggcagttgag gaggagggag cgcttgaggg    120
ggactggcct ggcgtgcact ccgcacctcg gggacattat tgcgcgtgga acggctgctt    180
ttggaaggca caacttcctg aatggaccat gactcccacc aaagatccct gtctctgatt    240
caccaaacag cttcaaccct gaaaccagga cgagaagttg acaacatctg agtggacagc    300
taattgacct aagacttcag accaggcctg tatgatctcc tgtctaaaca ttcttagagt    360
attatattta ctttggggac tattggcctt gtctgctttg actcagatta taggatatat    420
aacctggtta atgtttcygt acacatgatg gccacctatg tatatacact tgacttttca    480
gggtctctgc tggggatgga aaaatagttc attagccaaa ctctcctaaa gtgtggcana    540
tggaggcagt ctctcagatt gctggatttg tcaccatctt agggccatct caagatcatt    600
acatgctact tgttgcacca gagattgatt tttctgacac tccaaatgtt accatatact    660
tacatcagtt ccctccaaat gtcactttcc aaattcaaat tcagcttcta aagccaggcc    720
atattttcat tctgtgctta gtaataagcc ctaagtctca cccttcccca ccgcccccag    780
gtctatctat cagtaagcca attagggaca aattctctaa cttatctaga acacaractt    840
aattcctcat cttttccagg tccctgcaca ttcctggcct cccaccgkta ctgtcataac    900
tggcaactga atgtccaaag gagaaaaagc aaagcagatt gtgccagcac gtctcatttg    960
ttatatatca tgcttatgca ggcctttgta aggcctgcag taaaaccaat ccatggctca   1020
ctcatgtttt aaacaactta cctattcaaa ctattatgaa tgaatagtta agagatacat   1080
tttggtatgt ggcattgggc cacacccacc aactcaagga tgggcacata gtgtaaatag   1140
ctggcaaaat agctggcaaa ttgaagggcg cttttttttt tttttttt                1188

<210> 813
<211> 1150
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1123)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1126)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1128)
<223> n equals a,t,g, or c

<400> 813
tcgacccacg cgtccgccag ggacaagtgg tgaagcatac aagagaagtg ctttgattcc     60
tcctgttggg tttacaggct gtgcatttgg atcagctgct atttggcaat atgaatcact    120
gaaatccagg gtccagagtt attttgatgg tataaaagct gattggttgg atagcataag    180
accacaraaa gaaggagact tcagaaagga gattaacaag tggtggaata acctaagtga    240
tggccagcgg actgtgacag gtattatagc tgcaaatgtc cttgtattct gtttatggag    300
agtaccttct ctgcagcgga caatgatcag atatttcaca tcgaatccag cctcaaaggt    360
cctttgttct ccaatgttgc tgtcaacatt cagtcayttc tccttatttc acatggcagc    420
aaatatgtat gttttgtgga gcttctcttc cagcatagtg aacattctgg gtcaagagca    480
gttcatggca gtgtacctat ctgcaggtgt tatttccaat tttgtcagtt acgtgggtaa    540
agttgccaca ggaagatatg gaccatcact tggtgcatct ggtgccatca tgacagtcct    600
cgcagctgtc tgcactaaga tcccagaagg gaggcttgcc attattttcc ttccgatgtt    660
cacgttcaca gcagggaatg ccctgaaagc cattatcgcc atggatacag caggaatgat    720
cctgggatgg aaattttttg atcatgcggc acatcttggg ggagctcttt ttggaatatg    780
gtatgttact tacggtcatg aactgatttg gaagaacagg gagccgctag tgaaaatctg    840
gcatgaaata aggactaatg gccccaaaaa aggaggtggc tctaagtaaa actgggattg    900
gacagtagtg gtgcatctgg tccttgccgc ctgagagccc caggagacat cggctagagt    960
gaccatggct atgctcccgt ctggaagatg ccagcatctg gcctcccact gttttcagct   1020
gtgtccccca gtccgtgtct ttttagaatg tgaatgatga taaagttgtg aaataaaggt   1080
ttctatctag tttgtaaaaa aaaaaaaaaa aagggcggcc gcnctngngg acccaagctt   1140
acgtacgcgt                                                          1150

<210> 814
<211> 595
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<400> 814
gccaggcacg gtgtcagcag gcaacatggc cgagagcggn ggcctccggg cggcgccgtg     60
tccgcgaccg cgtaccctga cacccccgcg gaattccctc cgcacctcca ggcgggtgcg    120
atgcggcgcc gcttttgggg cgtattcaac tgtctgtgcg ccggcgcgtt cggggccctg    180
gccgccgcct ccgccaagct ggccttcggc agcgaggtga gcatgggttt atgcgtctta    240
ggcattattg tgatggcgag caccaattct ctgatgtgga ccttctttag ccggggcctc    300
agtttctcca tgtcttcagc cattgcatct gtcacagtga ctttttcaaa tatcctcagc    360
tcggccttcc tggggctatg tgctgtatgg agagtgccag gagtcttgtg gtggggarga    420
gtgttcctta wtctctgcgg gacttcacct aatccacagg aagctcccac ccacttggaa    480
gccccttcca cacaagcagc agtagcaacc acttggctaa gacggaccag ctggaaagat    540
catgatggtt gggcccagct ttgggatgtc aagtgggaat tgtgttccta agggg         595

<210> 815
<211> 2110
<212> DNA
<213> Homo sapiens

<400> 815
ggtctgccac aattctttct gcagctcctg aggaagtgat gggagtagac agattcacag     60
tgaacaagag atttgggaga ccaagtgggc ataaaactac gtcttggcct ctatttggaa    120
atctgaatga tggaattatt atgtttgtwa aaagtaccaa aaagccaagg gttaattcat    180
ttaggttctc tctgttttcc agcaaatgga actctgattt aaacagctgg ggatgaaatt    240
cctcaagatg attattcctg aaagtgtgga tgcgctggat gcgcagggaa catcaggaaa    300
aggccacggg gctctgaaca gccccggtcc agacagcagc ctgtacatcc atcccaggac    360
acagcccagc ccctccccac accatacaag gtatcagaaa agtctaggac ctatcatttc    420
atcagagaca tgatcagaaa agaaactgct tctgccccat ttcttgtttt ggagattact    480
ccatctgtcc atcaaaagaa acctgtaaat atgaaagaac aaaggttatt tcctggagaa    540
aagacaattt attcaacacc aacragggac tcatcatatg ggcacaactc tggtgtcctt    600
ctatggagaa aacctcaagt aaagttttat tctgcctttg aaaatgcttc caaaagtaga    660
ccctgtcccc acacaggtca agactacaga gaaggctttg tagaaatgtg tcacctatgt    720
acacctgcta cttacacatt tcctcttttg gaaaaatgag atacttagaa taacaagaaa    780
attaagacat actggcctgg tgccagcaga tggcttttct atagacaaac taggttagtg    840
tggaagatat aggttaaaat aaactatgct gttttattta tcttcccaac ctgattggca    900
gctagacttt tttagggtct catttaatgg ccctgttttt ttcattatta tatttaatga    960
tagggcagga tttcgtatgc aagctcttgt ttctcaggct gcctgcagaa gaagtcgcta   1020
taaattatct gttgtctaca tggtacaagg cccattgact catctgatgc ttgttttgtt   1080
aatttcttta atatttttat cacggggcag tgggagggct tgggctttta gccacagctg   1140
ttttaagact tctgatctcc tgccctgcag gaataggtgg gaagtcattg aatttttaca   1200
ctatagtaat ttgcattccc acataagttt gagtgttacg aaaacattcc tttaaaggga   1260
tctgtgctac acaaaatatg ccaggacctc acagacaaag ccattgctag aaatgtcatt   1320
ccaatgatca gatctggaaa caggctgcca taaccacttt tccttcttgt agactcagct   1380
cacctgtata tttaaactgt tcttggcatc ttgaaacacc tatttctact caggtactca   1440
ttgtcctgtt actgattcac ctttctgatc cttttcaacc agttttcccc caagggggga   1500
aattttactt aacctctagt atttgaacaa ctcaatattt gaattgttgc cccatttgct   1560
tttacctgta ctgtattctt ggtcatctca aatggcgtct aaacccagct actttgcatt   1620
ccagaagttt ccattccctc caattccacc taatttttca tctgtcctag ttactggctc   1680
tttcttcatg tcttatttct cttgctttgg gagcttaaaa gattttacaa gacctaattt   1740
tgggttcctt ccttggagcc atagttaccc tgccaagaag agtagaaaat gggttcaact   1800
cctgtttcgc tccaccaaca cctctgtgag tctcatcatc agctgagcga tgatgcctta   1860
caggttgcat agcactggaa ctttcctaga gtaacggctc tgctgccagg gtttctctgg   1920
gctcattctt ccactgactt aattatgatc tatgcctaac agagccccag tacaactatt   1980
ttgcagaatg gctgttaccc tagaattact atagcacata ttgagatata gttgtactcc   2040
ctagtagata ggaactgacc ccaacaataa actttgataa taaagaaaaa aaaaaaaaaa   2100
aaaaaaaaaa                                                          2110

<210> 816
<211> 515
<212> DNA
<213> Homo sapiens

<400> 816
gggcacgagc aaagggcagg gcgtgtctac cacccaccag cccactgggg tcccccttcc     60
tcgccgaggc ctccggagca tgggtctgct ggcccttcct ttctttgcca tcttagtcat    120
ggacagaggc tggcccaggg gcacctggct tcctgtgacc tccgggagac tccatgctgg    180
gcaaggcaga gtgacccttc ccctggcagg cgggggcatg aggctgccac ggggaacaca    240
ggtttccttg camctkgccc tttaccctgt cagctttgct gttttcatgt gctctgacgc    300
cctcccatta ggtgcatcca agctgcaatg cccacttcct cctggcaggg gggacccgca    360
ggcaccttct gctcagaggt gcacttgtct ggtggccctg ctccttcctg gtactgttga    420
cctttctgtg tgtttgtttt aaatctcttg catggtaaat agctgcattt tgttactgat    480
aagagtgagt ttaaatccac tgtcatatct tttga                               515

<210> 817
<211> 898
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (882)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (890)
<223> n equals a,t,g, or c

<400> 817
tcgccgcaca agggctccta cctgtacagc ctgaaggccc accacgtcaa gcaccacttt     60
gcacatcaga agtcaggatt tggtatcagc actaaattgt gggattactg tttccacacc    120
ctcactccag agaaacccca cctgaagacg cagtgacaac tcccaccccc tccgtcctgc    180
cctcagcccg gccctggccc cttcccgacc cccacccgcc attcagaccc cattaagaag    240
gttggcttgg ccaggcagga tgggctgtgt ccggccctgc agcctagtgg aaggtgctga    300
gggggccctg aggcaggacc gccctcctga cccctggtag gagggtcaca tccacttggt    360
ggccaggtgg cccttggtga cccacttctt cctggagcgt ccctgctaga gctcagccca    420
caggactgct tcaggccgtg gccacaggta gcagccgcaa ggggaaatga agaaaactga    480
gccctcgtgg ccacctgtgt cacccttgtg ccttagcctc atgggctgcc taggagctgc    540
ctgcacggca cagytcgctt tcacagtcag aagtgggtct gtgggatctg tggtccctgt    600
cctccctgct gtcccttctg gggaggcttt ggtggctctr aggtggacaa agagctctcg    660
caagaagaga cagcgtgatg cctcccacag tccaccccag accctggggc aagcccctct    720
tggccctgca gcttgcctgc gtcgttgggc ccagggtggc tggcaaggag tcccagctgc    780
ttgctttagg acctcgcagt ttttcttgcc gtccctcccc tgcctccaga atcacagccc    840
ttctccccaa ggaggctgag gaggcttctc caccagtggc antcccaacn cgtccctg      898

<210> 818
<211> 770
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (366)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (699)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (708)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (737)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (767)
<223> n equals a,t,g, or c

<400> 818
atgctcaagt ggatgtacat cccagcaagt aacaacaaca ccccaatcca tggcttttat     60
atctattatc gacccacaga cagtgacaat gatagtgact acaagaagga tatggtggaa    120
ggggacaagt actggcactc catcagccac ctgcagccag agacctccta cgacattaag    180
atgcagtgct tcaatgaagg aggggagagc gagttcagca acgtgatgat ctgtgagacc    240
aaagctcgga agtcttctgg ccagcctggt cgactgccac ccccaactct ggccccacca    300
cagccgcccc ttcctgaaac catagagcgg ccggtgggca ctggggccat ggtggctcgc    360
tccagngacc tgccctatct gattgtcggg gtcgtcctgg gctccatcgt tctcatcatc    420
gtcaccttca tccccttctg cttgtggagg gcctggtcta agcaaaaaca tacaacagac    480
ctgggttttc ctcgaagtgc ccttccaccc tcctgcccgt atactatggt gccattggga    540
ggactcccag gccaccaggc cagtggacag ccctacctca gtggcatcag tggacgggcc    600
tgtgctaatg ggatccacat gaataggggc tgcccctcgg ctgcagtggg ctamccgggc    660
atgaagcccc akcagcactg cccaggcgag cttcagcang tagcgcantc ttgggtgtgg    720
gcggcagtat gggacancca gaaggattgc tgggctgctt ggggggntct               770

<210> 819
<211> 737
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (49)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (513)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<400> 819
nacaggcacc agcattcact aacaatggcg gtgttttcgg cgacgtttnt acgcttatcg     60
gttcactgac ggcagttgcg ctgtaccgtt atcgctttcg tggtaagccg ttcgttagcg    120
gaatgctgtt tgtggtgatg atgtcaccag atatcgtgat ggcgatttcg ctgctggtgc    180
tgtttatgct gctgggtatt cagcttggct tctggtcgct gctgttctcg catatcacct    240
tctgcctgcc atttgtggtg gtgacggtgt attcgcgcct gaaaggtttt gacgtgcgaa    300
tgctggaagc ggcgaaagat ctcggtgcca gcgaatttac cattctgcga aaaatcattc    360
tgccactggc aatgccagcg gtggcgrcgg gctgggtgtt aagctttacc ctgtcgatgg    420
acgatgtggt agtttcttcg ttcgtcaccg gaccaagtta tgaaattctg ccgttaaaaa    480
tttattcgat ggtcaaagtc ggcgtatcgg ggnagttaac gcgctggcaa ccatattact    540
ggtgctgtcg ctggtgatgg ttattgccag ccagcttatt gctcgtgata aaacgtttag    600
atgtctaaat aaaacaatga aggacaacac aacatgcctc acaatccnat ccgcgtggtc    660
gtcggcccgg gctaactaan tttccacatc ccagggaagt tttcaattca actggcacga    720
attttttcca cggatgg                                                   737

<210> 820
<211> 1034
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (116)
<223> n equals a,t,g, or c

<400> 820
gcggacgcgt grgacaaagc ggagaacgct ggtgggcctg ttgtggagta cgctttggac     60
tgagaagcat cgaggctata ggacgcagct gttgccatga cggcccaggg ggctgngttg    120
gctaaccgag gccggcgctt caagtgggcc attgagctaa gcgggcctgg aggaggcagc    180
aggggtcgaa gtgaccgggg cagtggccag ggagactcgc tctacccagt cggttacttg    240
gacaagcaag tgcctgatac cagcgtgcaa gagacagacc ggatcctggt ggagaagcgc    300
tgctgggaca tcgccttggg tcccctcaaa cagattccca tgaatctctt catcatgtac    360
atggcaggca atactatctc catcttccct actatgatgg tgtgtatgat ggcctggcga    420
cccattcagg cacttatggc catttcagcc actttcaaga tgttagaaag ttcaagccag    480
aagtttcttc agggtttggt ctatctcatt gggaacctga tgggtttggc attggctgtt    540
tacaagtgcc agtccatggg actgttacct acacatgcat cggattggtt agccttcatt    600
gagccccctg agagaatgga gttcagtggt ggaggactgc ttttgtgaac atgagaaagc    660
agcgcctggt ccctatgtat ttgggtctta tttacatcct tctttaagcc cagtggctcc    720
tcagcatact cttaaactaa tcacttatgt taaaaagaac caaaagactc ttttctccat    780
ggtggggtga caggtcctag aaggacaatg tgcatattac gacaaacaca aagaaactat    840
accataaccc aaggctgaaa ataatgtaga aaactttatt tttgtttcca gtacagagca    900
aaacaacaac aaaaaaacat aactatgtaa acaagagaat aactgctgct aaatcaagaa    960
ctgttgcagc atctcctttc aataaattaa atggttgaga acaatgcata aaaaaaaaaa   1020
aaaaaaaaaa aaaa                                                     1034

<210> 821
<211> 629
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (540)
<223> n equals a,t,g, or c

<400> 821
gcgaattatt ggttggggga aacccacgag gggacgcggc cgaggagggt cgctgtccac     60
ccgggggcgt gggagtgagg taccagattc agcccatttg gccccgacgc ctctgttctc    120
ggaatccggg tgctgcggat tgaggtcccg gttcctaacg gactgcaaga tggaggaagg    180
cgggaaccta ggaggcctga ttaagatggt ccatctactg gtcttgtcag gtgcctgggg    240
catgcaaatg tgggtgacct tcgtctcagg cttcctgctt ttccgaagcc ttccccgaca    300
taccttcgga ctagtgcaga gcaaactctt ccccttctac ttccacatct ccatgggctg    360
tgccttcatc aacctctgca tcttggcttc acagcatgct tgggctcagc tcacattctg    420
ggaggccagc cagctttacc tgctgttcct gagccttacg ctggccactg tcaacgcccg    480
ctggctggaa ccccgcacca cagctgccat gtgggccctg caaaccgtgg agaaggagcn    540
aggcctgggt ggggaggtac cargcagcca ccagggtccc gatccctacc gscagctgcg    600
agagaaggac cccaagtaca gtgctctcc                                      629

<210> 822
<211> 682
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (600)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (660)
<223> n equals a,t,g, or c

<400> 822
attttgctca tcaacctcat tatagaacat atgatttgtg atacagatcc tgaacttgga     60
ggagcagtcc agcttatggg cctgcttcga actttagttg acccagagaa catgctagcc    120
actgccaata aaacagaaaa gactgaattt ctgggtttct tctacaagca ctgtatgcat    180
gttctcactg ctcctttact agcaaataca acagaagaca aacctagtaa agatgatttt    240
cagactgccc aactattggc acttgtattg gaattgttaa cattttgtgt ggagcaccat    300
acctaccaca taaagaacta cattattaat aaggatatcc tccggagagt gctagttctt    360
atggcctcga agcatgcttt ctkggcatta tgtgcccttc gttttaaaag aaagattatt    420
ggattaaaag atgagtttta caaccgctac ataatgaaaa gttttttgtt tgaaccagta    480
gtgaaagcat ttctcaacaa tggatcccgc tacaatctga tgaactctgc cataatagag    540
atggttgaat ttattagagt ggaagatata aaatcattaa ctgctcatgt aattgaaaan    600
tactggaaag cactggaaga tgtagattat gtcagacatt taaaggatta aaactgagan    660
ttgaccacca aagagaaggc aa                                             682

<210> 823
<211> 988
<212> DNA
<213> Homo sapiens

<400> 823
tgtctgcagg tccaaaggca ccgtcctgag ttggaaaaag atgaatcaga cccagtccct     60
ccctggagtt gctcagaggt ctggaggaga aaggcataga gagaacagcc ccagcccagg    120
tgggaaggag gcagaaactc ggcagcctgt ggtgattctc ttgggctggg gtggctgcaa    180
ggacaagaac cttgccaagt acagtgccat ctaccacaaa aggggctgca tcgtaatccg    240
atacacagcc ccgtggcaca tggtcttctt ctccgagtca ctgggtatcc cttcacttcg    300
tgttttggcc cagaagctgc tcgagctgct ctttgattat gagattgaga aggagcccct    360
gctcttccat gtcttcagca acggtggcgt catgctgtac cgctacgtgc tggagctcct    420
gcagacccgt cgcttctgcc gcctgcgtgt ggtgggcacc atctttgaca gcgctcctgg    480
tgacagcaac ctggtagggg ctctgcgggc cctggcagcc atcctggagc gccgggccgc    540
catgctgcgc ctgttgctgc tggtggcctt tgccctggtg gtcgtcctgt tccacgtcct    600
gcttgctccc atcacagccc tcttccacac ccacttctat gacaggctac aggacgcggg    660
ctctcgctgg cccgagctct acctctactc gagggctgac gaagtagtcc tggccagaga    720
catagaacgc atggtggagg cacgcctggc acgccgggtc ctggcgcgtt ctgtggattt    780
cgtgtcatct gcacacgtca gccacctccg tgactaccct acttactaca caagcctctg    840
tgtcgacttc atgcgcaact gcgtccgctg ctgaggccat tgctccatct cacctctgct    900
ccagaaataa atgcctgaca cctccccaca aaaaaaaaaa aaaaaaaact cgaggggggg    960
cccggtaccc aattcgccct ataaaggt                                       988

<210> 824
<211> 476
<212> DNA
<213> Homo sapiens

<400> 824
acagaagggg aggcgccttg gacgcggagc cgtgggacga gggcggcgat ggcgtcccat     60
gtagagtgcc gtcctctggg agtgtttgag tgtgaactct gtaccttgac agctccgtac    120
agctatgtgg gacagaagcc ccccaacacc cagtcgatgg tcctcctgga ggaaagctat    180
gtcatgaagg atcccttsac ctccgacaag gacagattcc tggtcctcgg ctcgtgctgc    240
agtttgtgca gcaggctggt gtgtgtgggc ccggaatgca gtttattcta ctccagagat    300
tctgcctycc ttgtgtccgg gagaacatca atgcttttcc tcaggaaatt cggcaagact    360
tggagaaaag gaaagctcca tcaaagagga cccccagcca gcccggttct yggacgtgar    420
tgcaactggg gctaggtcat cgggcggacc ctkcacagar ctyctgggcc agcctg        476

<210> 825
<211> 2520
<212> DNA
<213> Homo sapiens

<400> 825
ggggcggggc ggagccttga ttcccagtgc cataacttct gggggaaacc tccgtctccc     60
gtccctatgg tgaccacagc agcagagggg gatccttcca tgccccaggc aggctggcat    120
cagggccaca caggggccag gagcaggggt ctcggagtcc acarctcccg gccccagtgg    180
tgggctcagg gctcctgggc gccatgggtc tcaccacagc ctcgccaggg aacaggacca    240
tagggagtcc ttctccccat ctctagccac ccacaggcca gcagagcaca cagccccacc    300
ctcgcacagg cacctgtggt ctcccagtaa ccaagcccca gcccaggggc cactgcagac    360
agcagctggg atctgcagag ggatctcagc agcgagcagg cagctggcga ggagaggtgc    420
gtgtgaggga ggggtggccc tctcctcagt aggaggaagt aagagggtat ctaggccaat    480
ttattcagct ggaaatcaat ctgtccaggg ctggaccagg cgcctccccc tcgatacagc    540
tcctggctga agaggtcatc agagcagcag ctgtccccag gccagtgtca cgtcactgcg    600
tacagttcct cccgatcgtt cttgcagatc tgatagtggc aggggaattt ctgcgagcag    660
gcccagggct cggcgggctg gtcaggtggc ggcagcagca aggctgcgct cccggccagc    720
aggatgtgcc agatgctgtg ggtgtagtag tagttgtcgc tagtcatcat ggaggtgtag    780
atggcgatgc ccacagaggc catagagacg ccgggcagga ggtagaaggc ccagcgctgc    840
cacgaggtgg ggtagcactg gcgccggtgc ccgcagcggt aagcccacat ggaggccatg    900
atcacgaagg caaagaggca gggccccagc atgttccaca tgcccctgcg gtccagctgc    960
aaggacatgg cgatgaccag tgtacccaga agaaacagca cgtatttcag gactgtcttg   1020
agccgtgcca tgcacaggat ggtgacccag atggccgccc cggagcccaa gaagtcgcag   1080
tactgcagcg tgtcgtagct gaggatgcac agcaccgcct ccccgggctg gtcgcaggcg   1140
tggtagaacg tggagaagaa catggtgtag gcgtagacgg aggcctccac caggaagaat   1200
cgccgcactg agacggcgat gggggccagg aacatgaggt tgctgagcgt gagcagcagt   1260
gtggccgccc tctgctgggc caccgtctgg gctgtgctgt tgtccgtgca gctccaccca   1320
cgccagcctg ccttgcagct gcagctggca tacaggtagc tgtgtctgcg gagcaggagg   1380
cactggccat agggtccaca atcgttcaaa cagggcacca ggtacaaggt ggtctccacg   1440
tggaccacag cctgctcaca gtcctcagca ttctcagggc acatgagctg cagggagagg   1500
taccagttgt ctgtctctgg gtaggggatg atgaggttgg ccctgcgaga ccaggcgctc   1560
agagacaaag ggtagccctg gaagaaggct gtggtgcagt tgagcgaagt attgaagcca   1620
aggaagggcg aggcagcatt cacgcaggcc actacgacgg tctcgttccg catctctgtc   1680
ttgttggccc gcagggagat ggtgagggaa cccccgctgt ccatgccggt gttcaggcgc   1740
agccgcatca cggagggcgt gtccgaacac accctcaccg agaccctgtc caggggctgg   1800
aagtgcaccg acaccacgtc catgtcctcc cgcgtgactg ggtagtttgt gaggcagaag   1860
gggctgcggt ccaccctgcc actcctgccc aggtcctggt ggtcggggct cggggacagc   1920
agaccagagg aggcattgaa gctctggttt tggstgctct gcagaagggg ctggayggtc   1980
acgctccgtg gcctgcaagc tgtgagggca gctacagcac tgaaagccac tgtcccgagg   2040
ggccccacca ggctctcagc tgtyacttgc agccaccggt cccagggcgg tgagggcagc   2100
agcaggcggc agggccaggg ggcaccggtg caggtgagca ccttctggaa gttgctaggc   2160
agggtgaccg ggcccacggt kagacgcacg gggcagccca ggctcccatt ggacacgcag   2220
tcccgcagct ccagcagaag ctcccgcgtg taatcgggga caaagacctt gaggtagctg   2280
ggatgggaga ggagggtctg aggaaggggc acgtccggct ccatgatgga aatctcgacc   2340
acccgcgtga ccagcagttc aggctggaag acgtaggcac aggtgggagc caagcccttc   2400
aactcgatct tctgggatga ggggggcagg tggkcggcca cgaaccagtc cccgggggcc   2460
gggtggraaa cgttgacgga ggcattgctt ctcggtgcgg tgctcagcgg caccccgacc   2520

<210> 826
<211> 942
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (33)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (942)
<223> n equals a,t,g, or c

<400> 826
aatggtgggt cccccgggct gncaggattc ggncacgagg atggggagaa ggactcccta     60
tggtcctgtt ccctggcgag gctgtggtga gacccatggc gcccaggagc cctgagccca    120
ccactggggc cgggagctgt ggactccgag acccctgctc ctggcccctg tgtggccctg    180
atgccagcct gcctggggca tggaggatcc ccctctgctg ctgtggtcac catagggacg    240
ggagacggag gtttccccca gagctgatgg gcactgggga tgcaggctcc cgccccgccc    300
ctcccttttt cctggctctg gagccttggg tccctgagaa gagcttcctt ggactggggt    360
gctctgctgc tctgggggtt tggcccagaa ggaaccccta cccagccctg tccacccacc    420
ccagcgttcc tgggcccccc tctgggagct tcctcttggt cccaggagct gcggtggtgt    480
ctgccccctg cactgggctc tgtgccctgt gggtgttcag gagactggac tgtctctgct    540
cctcatgcaa accttgtggg ggaagcaatg accaggagca gcacctggcc cctccctgag    600
gcctgtgagt gtctcggatc cgccctggag aagtgagtgg ctgagacccg ggtggggccc    660
tcctaccctt ggctctgggg gcttcccttc tgggtcttgt ccgggatatg gccttcctga    720
aggtcttacc tcccccagcc gccctgcact tgaccaccaa agcaatctct aagcttataa    780
aggagaaaca trtatatatg gggttttttg gagtaaagga aaattctaag atattaagac    840
atatttttat gtagatctga tctatctgtg tttggtgaat ttaatattct acattgattt    900
ttcaaactaa aaaaaaaaaa aaaacctggg ggggggcccc gn                       942

<210> 827
<211> 1850
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (25)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (519)
<223> n equals a,t,g, or c

<400> 827
agaggcttgg aaagctnngt gtctngggaa aaaaaggcct ttgagcatat gggtccagcc     60
actcagaagt gcaggggcca tgcttggtgt tccaataagt gaatggaagc agtggtggta    120
gctacactgg gcagagttgg cagggtgctg gttcactctg cccagccctg aatgtgtgcc    180
ttaaaggccc cctacaaggg ccscatacga cagagctttt aactggtgcc ttccctgtac    240
ccgcagcagc cacaagtggg cccagactat tgcagcctcc cataaacatg tgagcatgtt    300
ctgagtgtgc catgatgtga gtggacctgg ctggaatctt cggagagcga ctgaggtgtt    360
caaatcgaat ctcccaggag gcttccttcc agccccctat tctggtaact accaggaggc    420
ttccttccag ccccctattc tggtaactac caaaatccct cgggtgcaag tktaggggta    480
gagatggaag gatgagaggt gaaattgacc ttttgaaang caaagctctg gctcacaggc    540
cccaaactac cagcccgtat ctagcatatc cccaccctcc acccacttac ctcctccaac    600
aaaggagtca actcagttga aaaaactggt cctttggsct atccatgggt caaagtccac    660
ctctcctggg ggsctggara ggmctgagcc tacggaaagg ggataccttc ccactcagca    720
ctgcttcaca caggccccct gcctggggct ctccaaggag ccttcttcas ccacttccag    780
ctccacttct gcaaggttaa gtcaagtgag aacgatraga aatagggaga tggtgtctcc    840
ttaagtcctt gatctgcctg tctgtggaat gggaggttgg attagctgcg ctgaggtccc    900
atccacagct ggtgctcagc tgcttgaagg ggagactccc tcctctgtaa cttctttctg    960
ggggatyggg gtgggcagta cctatcccca gtcccctcct agcttgactt tagtggtttc   1020
caatgtagaa gttaacaaag tatgccccat tcctgtgaca aaagcacaac cattctgaag   1080
ttactggagc atgggctcag ctcatcctcc ctctggcccc ttctcccatg gggacatctc   1140
ggcccagcac ccctatccca tttccagagt tcttccttcc ccatytgggc cttcataaaa   1200
tgcaggggaa gccagactgg tctcaggagc gctaaagccc ttccgtgggg ggtcgtcttt   1260
ctgggactag ccctgctgtt taggacctgg gaccacaatg gggtacctgc cgagggggtc   1320
cccaagagat ccaggctgtc atgtgattta tggtggcatg tgttgtgtat ttgttggcta   1380
cttgtgtctt gaaatctaga attatttcac gcagaattgt cactgtttgt caggaagaga   1440
aaatgggcta gtggaagccc agtcttgagt tcttgtcttg ttaccattta aaattgacat   1500
ttaattttca aatcactgtt ggtgcctaat cacttaagtt attaatttat tctgttgtat   1560
tctttttttt aaattgtaac atatttatcc ggtgggtggg acaggagtgt gttcaagtgg   1620
gtcatgtttt tgctgtggtg acacatggta caggcttgga gcttgcaggt ccctttctac   1680
tgtggtgttg gagcaggaca ataaagtcca ctagaaatgc accccaraac cagctgccgt   1740
gtccatcttg tcttgagggg cttggtggtg gaacccgttc tcactccagt ctgttccaat   1800
ttttgcttta tttggaaata attgggtatt tttcttggct gtgaataaga              1850

<210> 828
<211> 761
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (209)
<223> n equals a,t,g, or c

<400> 828
ccntgcgctc ttggaaaggc tccctaggca atggccgagt ctctgctcca cccggctctc     60
aggagcgctg ctctctccat ctgatcgccc tccatcctcc ccattccctc cggttccggg    120
mtctcccttc gctccaagcc tcaggccacc ggcttggatg gacgctccga ggctacccgt    180
gcgtccaggg gtcttgcttc cgaattggnc ctgctctttg tctacgcaga tgattgcctt    240
gctcagtgtg ggcaaagatt gcaaatctta ctgctgtgat ggaamcacgc cctactgttg    300
ctcctamtac gcttatattg ggaatatcct ctcgggcact gcaattgcgg gcattgtttt    360
tggaataata tttatcatgg gggtcattgc tgggattgcc atatgcatct gcatgtgcat    420
gaagaacaca gggcgaccgc gtgggcatcc tcaggacgac tcacatcaac accgtctcct    480
cctatcctgg amcaccaccc tacggtcacr accacgagat ggaatactgt gcagacttgc    540
ctcctccata ctcccccacc ccacagggtc cagcacagcg ttctccaccc cctccttatc    600
ctggaaacgc aaggaaataa tctatctccc agaacagaac atgtgccaat gggcgatctt    660
gcctggaata aaatgcctct actcagaaac aggcaggaaa gaattgctcc aaggaatact    720
ttttggggtc agataatgtg tcaggtggaa tatccctgct a                        761

<210> 829
<211> 1266
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1258)
<223> n equals a,t,g, or c

<400> 829
ttgcagcctg cgtgctgggc ggcattagtt tgctcggtgg ttccggtgcg atcattggtg     60
cggtactcgg cgcatggttc ctgacgcaga tcgatagcgt actggtgctg ttgcgcattc    120
cggcatggtg gaatgatttt atcgcgggtc tggttctgct ggcggtgctg gtgtttgatg    180
gacgcctgcg ttgtgcgctg gaacgtaatc tacggcggca aaaatatgcc cgctttatga    240
cgccaccgcc atccgttaaa cccgcttcgt caggtaaaaa acgggaggcc gcataatgcg    300
tattcgctac ggttgggaac tggctcttgc cgcactgctc gttattgaga ttgtcgcatt    360
tggtgcaatt aacccgcgaa tgttagatct caatatgttg ctgttcagca ccagtgactt    420
tatctgcatt ggcattgtcg ccctaccgct aacgatggtg attgtcagtg gcgggatcga    480
tatttcgttt ggttcgacca tcggcctctg cgccattgca ttgggcgtac tgtttcaaag    540
tggtgtgccg atgccgctgg cgatactcct gaccttactg ctcggcgcat tgtgcgggct    600
gatcaacgcc ggattaatta tctataccaa agttaacccg ctggtgatta cgcttggcac    660
gctgtatctg tttgccggaa gcgctctgct gctttccggt atggccggag cgacggggta    720
cgaaggtatt ggtggattcc cgatggcgtt tacagatttc gctaacctgg atgtgctggg    780
actccccgtt ccgctgatta tcttcctgat aatgtctcct cgttttctgg ctctggctgc    840
ataaaaccca tgccggacgt aatgtgtttt tgattgggca aagccccgcg cgtggcgctt    900
tatagcgcga ttccagttaa ccgtacctta tgtgcgctct atgccatgac ggggctggcg    960
tctgcggtcg ccgctgtgct gctggtatcg tattttggtt cagcacgttc cgatctcggt   1020
gcgtcgtttc tgatgcccgc catcaccgcc gtggtgcttg gcggggccaa tatttatggt   1080
ggttccggtt ccattatcgg caccgccatt gcggttttat tagtgggata tttgcaacaa   1140
ggtttgcaaa tggcaggagt gccaaatcag gtgtccagcg ccctttccgg tgcgctactt   1200
atcgtcgttg tcgtaggtcg ttccgttagc ctgcatcgcc agcaaattaa agagtggntg   1260
gcgcgt                                                              1266

<210> 830
<211> 701
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (571)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (600)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (636)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (653)
<223> n equals a,t,g, or c

<400> 830
actccgtctc aaaaaataat aataataaaa aagtatagtg tgcctggatg cagttttgtt     60
tttatttatc ctgcttgggg atcataaagc tttatcagtt ttggaaagtt ctcagcctat    120
atttatttaa ctgttccttc tgccccatct tcctcccttc ttctaagact ccagttacgt    180
atgtattagg cctgttcacc acttcccaca agtatcttat gttctttgct gtattttcca    240
tactctttgt ctctgttttt cagcttagag tttttattct gtcctgtatt acagttcaaa    300
gaatgttcct tctgctaaat ctaattgtag ttaacccata tgctaagtac ttaatttcag    360
ttattgtatt tttaagtttt aaatttccat ttcattcttt cttatagatt ccagttcttt    420
gatgaaagtc tctattccac ccatcaagtc tgtgtctgat aacaccaata tctgggtcat    480
tagtggctcc gtkttgttgt gtctgtkttc ccctcctgag ctcaagggat ccacctgcct    540
cgacctccca cagtgctggg attagtggga ngagccacag cacctaagta tgtcttgggn    600
aatttaaatg agaccgagag gcagacatta tcttgnaaat cccatatcca gantcctttc    660
tgcaaaaatg gaaaacaggg aggggtaaag gcatggtact c                        701

<210> 831
<211> 894
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (849)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (853)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (860)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (863)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (893)
<223> n equals a,t,g, or c

<400> 831
ggaagaagaa gaagagcatg atcggcatgt ccaccaaggc agtgctctgg cgctgcttca     60
gcaccgtggt catctttctg ttcctgctgg acgagcagac gagcctgctg gtgctggtcc    120
cggcgggtgt tggagccgcc attgagctgt ggaaagtgaa gaaggcattg aagatgacta    180
ttttttggag aggcctgatg cccgaatttc agtttggcac ttacagcgaa tctgagagga    240
aaaccgagga gtacgatact caggccatga agtacttgtc atacctgctg taccctctct    300
gtgtcggggg tgctgtctat tcactcctga atatcaaata taagagctgg tactcctggt    360
taatcaacag cttcgtcaac ggggtctatg cctttggttt cctcttcatg ctgccccagc    420
tctttgtgaa ctacaagttg aagtcagtgg cacatctgcc ctggaaggcc ttcacctaca    480
aggctttcaa caccttcatt gatgacgtct ttgccttcat catcaccatg cccacgtctc    540
accggctggc ctgcttccgg gacgacgtgg tgtttctggt ctacctgtac cagcggtggc    600
tttatcctgt ggataaacgc agagtgaacg agtttgggga gtcctacgag gagaaggcca    660
cgcgggcgcc ccacacggac tgaaggccgc ccgggctgcc gccagccaag tgcaattgaa    720
ttgtcaatga gtatttttgg aagcatttgg aggaattcct agacattgsg ttttctgtgt    780
tgccaaatcc cttcggacat ttytcagaca tctyccaagt tcccatcacg tcagatttgg    840
agctggtanc gcntacgaan ccnacaacgt gtgaacatct gtcttggtca aana          894

<210> 832
<211> 2516
<212> DNA
<213> Homo sapiens

<400> 832
attttcataa tcatacycag aagcaaactc tcaagcagca agcatatgca gctagtttac     60
cccattatmc mcttaaaaat tttatattta ccttagagct ttaaatctct gtaggtagtt    120
tgtccaatta tgtcacacca cagaagtaag gttccttcmc aaagatccca agctagcaga    180
tctcccagtc acgacgttgt aaaacgcggc cagtgcctag cttataatac gactcactat    240
agggagagag ctatgacgtc gcatgcacgc gtaagcttgg gcccctcgag ggatcctcta    300
gagcggccgc cctttttttt ttttttttta gatttactta tcttacttta ttcataaata    360
agaattttcc taagtgcagt gaggggtagg agacatggaa acctttctca tacttatagg    420
tgatattaaa ctgaaatata taactgcctt ttgggaacag tattttttct gttttctatg    480
aattacccat aagcatagca aaaccaagat aaatttaaat ttaatattgt taaagagcac    540
tgttcaagat aaactttcat gtatatcaca gtatagcatt atacaatgat tttacgtaaa    600
aatatttaga agcacagtga tgattttaag aagccataaa acattttaat gaaatataag    660
aaagtcatga atatttatgt ggatatgtat gttgcaaatt taaggtaaat caacatagga    720
taaacacaga agattacata caaaccctac atattttatt tctggtgaaa catataaaca    780
ctttcctact atagtacaaa atcaattagt tcctctacca gcactaaaga cttgtcatct    840
aaatatattc attttagggg agaaaaaaat gcttcacatt tttctaaaat aaagactgca    900
ataaattagt gctttaaaaa atatatatat ataggatata gatcctaaga aaataaaact    960
aaagtataaa aaatgaatag catttctttt cctgccatca tatcctttct tatctcattc   1020
ctacatagaa tgaatgataa gctaaattat ttagacatgt atggtgactg aaagcaatgt   1080
cttcaaggaa acagcttctt gtttagcctc ttactctacc atacttagag taaaaatcaa   1140
aggatatttt agaaatatct tgtaactatt gttgtagcaa taatctgtct tgttagaaca   1200
acacaataaa aatgacctag agaattccat gaacaatgat acttggatta caagagagct   1260
aaaaatcaga ggctattcct gtgtgcaaac tatttttacc agtctaaata ctatatggtt   1320
taccactgaa cacccaagtt tgactgaagt gaacatttgc tactatcagt aaaaaactcc   1380
ctctcttaca ggaatggcag aaatatagac atttagtcat caaaaatggc acaatgtaca   1440
tcacacaaat gattatatta tggttcataa ggaaaacagc cacaattttg atcagagaaa   1500
tgttaataca tatgaagcct taaaacagca acatggcggg gaaggagagg gaggcgggaa   1560
cctaatgcat ttgaattaaa ggaaacaggc aatatttggt cgatgtaaac aatgctattt   1620
aacgagtgct ttatctactt tactgaaata cggaaatact tatgtacacg atttaaatgt   1680
gcacaagact tgggcttttt tcttctagac tatgtacatc attcagcaca caattcaaaa   1740
agttctggtg tattcaacac actcccagta agattatgtt acactgaaac atataatatt   1800
aaactttcaa gagactgctt ttgatgctaa ggagtaatct atttttacaa gaatgctcaa   1860
tggtggtgat ttctagaata tctttttcaa tatcaccaaa aataagataa aatttatttt   1920
aaaattatga tttagaggta gagctgaaat tatttattta aattatagga aagaaagaca   1980
taaaatcatt gtgagagaat aatggtgaaa aacattcttg cctaagagtc tccatcttct   2040
ttggctatag ttgttgtttc aagttgaaac agcatcacta gtattgctgc cttcgaacat   2100
tttgtttctg gaaaaaagcc tttccaaatt catatgtact gatcataatg gcacaagcag   2160
gagcaatttt aattaagcga ggaattaggc ctgaaaataa tccggaaaat ccatttttag   2220
caacaatgtt cttcattata atccaggttg acatatgcaa aggcatagaa attttatgac   2280
tttcatatgt ccaaagttgt gtctgctttt gtgtttttac tacatcaaat ggtaaagttg   2340
caacagcagc aaaagaacca gacaatgccc ctgaagtaaa gttgatcata aatgttggct   2400
catataaacc agatttctca cataacccgg acgcgtgggc ggacgcgtgg gtcgacccgg   2460
gaattccgga ccggtacctg caggcgtacc ttctatagtg ycacaaaaag ctttta       2516

<210> 833
<211> 1624
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (883)
<223> n equals a,t,g, or c

<400> 833
gggcacccac cagcggcgcc gacctcagcg cgcacctatg ggctcgctac caggacatgc     60
ggagactggt gcacgacctc ctgccccccg aggtctgcag tctcctgaac ccagcagcca    120
tctacgccaa caacgagatc agcctgcgtg acgttgaggt ctacggcttt gactacgact    180
acaccctggc ccagtatgca gacgcactgc accccgagat cttcagtacc gcccgtgaca    240
tcctgatcga gcactacaag tacccagaag ggattcggaa gtatgactac aaccccagct    300
ttgccatccg tggcctccac tatgacattc agaagagcct tctgatgaag attgacgcct    360
tccactacgt gcagctgggg acagcctaca ggggcctcca gcctgtgcca gacgaggagg    420
tgattgagct gtatgggggt acccagcaca tcccactata ccagatgagt ggcttctatg    480
gcaagggtcc ctccattaag cagttcatgg acatcttctc gctaccggag atggctctgc    540
tgtcctgtgt ggtggactac tttctgggcc acagcctgga gtttgaccaa gcacatctct    600
acaaggacgt gacggacgcc atccgagacg tgcatgtgaa gggcctcatg taccagtgga    660
tcgagcagga catggagaag tacatcctga gaggggatga gacgtttgct gtcctgagcc    720
gcctggtggc ccatgggaaa cagctgttcc tcatcaccaa cagtcctttc agcttcgtag    780
acaaggggat gcggcacatg gtgggtcccg attggcgcca gctcttcgat gtggtcattg    840
tccaggcaga caagcccagc ttcttcactg accggcgcaa gcntttcaga aaactcgatg    900
agaagggctc acttcagtgg gaccggatca cccgcttgga aaagggcaag atctatcggc    960
agggaaacct gtttgacttc ttacgcttga cggaatggcg tggcccccgc gtgctctact   1020
tcggggacca cctctatagt gatctggcgg atctcatgct gcggcacggc tggcgcacag   1080
gcgccatcat ccccgagctg gagcgtgaga tccgcatcat caacacggag cagtacatgc   1140
actcgctgac gtggcagcag gcgctcacgg ggctgctgga gcgcatgcag acctatcagg   1200
acgcggagtc gaggcaggtg ctggctgcct ggatgaaaga gcggcaggag ctgaggtgca   1260
tcaccaaggc cctgttcaat gcgcagttcg gcagcatctt ccgcaccttc cacaacccca   1320
cctacttctc aaggcgcctc gtgcgcttct ctgacctcta catggcctcc ctcagctgcc   1380
tgctcaacta ccgcgtggac ttcaccttct acccacgccg tacgccgctg cagcacgagg   1440
cacccctctg gatggaccag ctctgcaccg gctgcatgaa gacccccttc cttggtgaca   1500
tggcccacat ccgctgaggg cacctttatt gtctgggaca ggccctcagc ccctcctgcc   1560
ccatccaccc agacaagcaa taaaagtggt ctcctccctg wraaaaaaaa aaaaaaaaaa   1620
aaaa                                                                1624

<210> 834
<211> 1203
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (44)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1098)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1191)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1194)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1195)
<223> n equals a,t,g, or c

<400> 834
nnncggggat gggaanttat gctcctctgg gttaagacca ggsncagctg gaaaaagtgg     60
aattggcaca ggcaacatct ttyttttyag atgtttgagg tcacccagag gagataacag    120
tctgtcaaca tagagccctc aaagttwaaa agcagtagcc aggcaagact tgtgtctttt    180
cagggctctt ccaggctcta agagtgtgaa attcagacag ktttttaaaa atcaaaataa    240
aaggagagta gttcttacag gcagaaactc ttagagctca caaattggaa acaactgcaa    300
acttcagagt aaattcatag cttccaaata caaatgttca cattgtccct ccgctatttt    360
tacacaaatg cattcaggtg aagacagcaa cacacattgg gaaaggacat ctgcttccta    420
ttttagtccc agaatcactt ttgcttctag tcccaactgt tccctctccc caatcccaac    480
cttatccatg taacagtatg aatttcctgg cccagagacc taaacaagaa gtcacgaata    540
tacctacttt tggttgcact tgccatttca atgcttagga aaacagagtg gtcagcaatg    600
accacactgg agatgagaga aaccattttc ggggagagat ttaagctgga ctctgcccct    660
gctcttggta agtggtgtct ccagttgctg cagtgcctgg aaccaaactc tgcctttcct    720
caattgcctg atatgctttc ttcttgaact tccgggtgcc gtagatggcc aaggtgataa    780
caacagccag aatggtggtg acccccactg tgaccccagc tgcagcccct cctgacagac    840
caccaccatc cccatggatg acattcatgg ccctccgcag ctctatcggt tctcccagcc    900
tccactggtg ggtctgggag tctttaatcc aggatctcgc attctcagaa ttggtcacta    960
tgacagtatt ggtggcagcc tgactcatga ggggtggccg gtgaaaggtg ggagcctggc   1020
agggggcagg gaccctyctg kgaagagccc ggatttgacg caataggaca cttggcatca   1080
tcgctgatga gggctggntg ctggctgaaa gcccccgggg cactttttca gagacggtgc   1140
cctaaatctc tggatatagc aggatctacc agggggttcc caactggcag nttnnggaac   1200
ccg                                                                 1203

<210> 835
<211> 662
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (638)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (653)
<223> n equals a,t,g, or c

<400> 835
gggagtgggt gcgcgggagg cgagtgagcc gggcgccggg ccctgggggc tcggcgggac     60
ggggasycag ggctgccagg cgcccagctg tgcccagatg gatgggacag agacccggca    120
gcggargctg gacagctgtg gcaagccagg ggagctgggg cttcctcacc ccctcagcac    180
aggaggactc cctgtagcct cagaagatgg agctctcagg gcccctgaga gccaaagcgt    240
gacccccaag ccactggaga ctgagcctag cagggagacc gcctggtcca taggccttca    300
ggtgaccgtg cccttcatgt ttgcaggcct gggactgtcc tgggccggca tgcttctgga    360
ctatttccag cactggcctg tgtttgtgga ggtgaaagac cttttgacat tggtgccgcc    420
cctggtgggc ctgaagggga acctggagat gacactggca tccagactct ccacagctgc    480
caacactgga caaattgatg acccccagga gcagcacaga gtcatcagca gcaacctggc    540
cctcatccag gtgcaggcca ctgtcgtggg gctcttggct gctgtngctg cgctgctgtt    600
gggcgtagtg tctcgaagag gaagtggatg tcgccaangt ggagttctgt gtnccagcag    660
tt                                                                   662

<210> 836
<211> 2694
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (258)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (925)
<223> n equals a,t,g, or c

<400> 836
ggcgccgcgc cgagcgaatc tcggagtcgg tgggtgcaga tggcggcggc agttgtggtg     60
gcggaggggg acagcgactc ccggcccgga caggagttgt tagtggcctg gaacaccgtg    120
agcaccggcc tggtgccgcc ggctgcgctg gggctggtgt cttcccggac cagcggtgca    180
gtcccgccaa aggaagagga gctccgggcg gcggtggagg ttctgarggg ccacgggcta    240
cactcggtcc tggargantg gttcstggag ktgctgcaga acgatctgca rgccaacatc    300
tyccctgart tctggaatgc catctcccaa tgcgagaact ctgcggatga gccccagtgc    360
cttttgctac tccttgacgc ttttggcctg ctggagagcc gcctggatcc ctacctgcgt    420
acctagagct gctggagaaa tggactcgcc tgggcttgct gatgggcact ggtgctcagg    480
ggctgcgaga agaagtccac actatgttgc gcggagtctt gttctttagc acccccagaa    540
ccttccaaga gatgatccag cgtctgtatg ggtgcttctt gagagtctat atgcagagta    600
agaggaaggg ggaagggggc acagacccgg aactggaagg ggagctggac agccggtatg    660
cccgtcgccg gtactaccgg ctcctgcaga gcccgctgtg tgcagggtgc agcagtgaca    720
agcaacagtg ctggtgtcgc caggctctgg agcagttcca tcagctcagc caggtcttac    780
acaggctcag tctgctggag cgggtcagtg ccgaggctgt gaccaccacc ctgcaccagg    840
tgacccggga gaggatggag gaccgttgcc ggggcgagta cgagcgctcc ttcctgcgtg    900
agtwccacaa gtggatcgag cgggnggttg gctggctcgg caaggtgttc ctgcaggacg    960
gccccgccag gcccgcatct cccgaggccg gcaacaccct gcgccgctgg cgctgcacgt   1020
gcaaaggttc ttctaccgca tctacgccag cctgcgcatc gaggagctct tcagcatcgt   1080
ccgagacttc ccagactccc ggccagccat cgaggacctc aagtactgcc tggagaggac   1140
ggacyagagg cagcagctgc tcgtgtccct caaggctgcc ctggagactc ggctcctgca   1200
tccaggcgtc aacacgtgtg acatcatcac cctctatatc tctgccatca aggcgctgcg   1260
cgtgctggac ccttccatgg tcatcctgga ggtggcctgt gagcctatcc gccgctacct   1320
gaggacgcgg gaggacacag tgcggcagat tgtggctggg ctgacggggg actcggacgg   1380
gacaggggac ctggctgttg agctgtccaa gaccgacccg gcgagcctgg agacaggcca   1440
ggacagtgag gatgactcag gcgagccaga ggactgggtc ccggaccctg tggatgccga   1500
tccagggaag tcgagctcca agcggcgttc atcggacatc atcagcctgc tggtcagcat   1560
ctacggcagc aaggacctct tcatcaatga gtaccgctcg ctgctggccg accgcctgct   1620
gcaccagttc agcttcagcc ccgagcggga gatccgcaac gtggagctgc tgaagctgcg   1680
ctttggcgag gccccaatgc acttctgtga agtcatgctg aaggacatgg cggactcccg   1740
ccgcatcaat gccaacatcc gggaggagga tgagaagcgg ccagcagagg agcagccacc   1800
gttcggggtc tacgctgtca tcctgtccag tgagttctgg ccgcccttca aggacgagaa   1860
gctggaggtc cccgaggata tcagggcagc cctggaggct tactgcaaga agtatgagca   1920
gctcaaggcc atgcggaccc tcagttggaa gcacaccctg ggcctggtga ccatggacgt   1980
ggagctggcc gaccgcacgc tgtctgtggc ggtcacccca gtacaggcgg tgatcttgct   2040
gtattttcag gaccaagcca gctggaccct ggaggaactg agcaaggcgg tgaagatgcc   2100
cgtggcgctg ctgcggcggc ggatgtccgt gtggctgcag cagggtgtgc tgcgtgagga   2160
gccccccggc accttctctg tcattgagga ggagcggcct caggaccggg acaacatggt   2220
gctcattgac agtgacgacg agagcgactc cggcatggcc tcccaggccg accagaagga   2280
ggaggagctg ctgctcttct ggacgtacat ccaggccatg ctgaccaacc tggagagcct   2340
ctcactggat cgtatctaca acatgctccg catgtttgtg gtgactgggc ctgcactggc   2400
cgagattgac ctgcaggagc tgcagggcta cctgcagaag aaggtgcggg accagcagct   2460
cgtctactcg gccggcgtct accgcctgcc caagaactgc agctgacaca tcgcccgccc   2520
gcccgcccgc ccgccaggcg ctgccctgca ggtgctctcg tcctcccgtg ccagcccccg   2580
cccgcccgtg tcccagaatg cactgctgag gagcatgccc acccccaccc ccgcagtgtg   2640
cagattaaag caagtcagat catcaaaaaa aaaaaaaaaa aaaagggcgg ccgc         2694

<210> 837
<211> 1989
<212> DNA
<213> Homo sapiens

<400> 837
gcggcacgag agagagagag agaactagtc tcgagttttt tttttttttt ttttgggcgg     60
gggggaggtt tatgaagtty tgctctttga accacagctt tattatggtc ctttacactg    120
gagacagaca cagagacact gttcagaaga tgaactaaac tcagcagtgg tctggtatca    180
agagctttct gatgttttac agcctgaatt tggagggata acgatctgct gtgcctttgc    240
agtcactgct tagcccaaag taatagtact tttgataata actcactctg tgcgatattc    300
ctgaataagt ccatctcaaa agtttgggat tttcctcctc ttaactttct taatatttgg    360
acatgcagtt gtcgccaaac ttgggtattc atggaatttc tagtaaatga aatacctata    420
ctttgatact gaagactgcc aaatacatag gaattttctt tcttaaaaaa cagtaatgaa    480
gactatatct cctttcccag cactgaatgt tttactagca ctgggtgctc accatgcaac    540
tgaagaaaat gtggaaactc aaaaggtcag gacagacttc caagcacttg caactgatgt    600
tactgtcttc aattttaata attacacata tttgtatatt tcagagaagt ttttaatatt    660
tctctgtcca ctttttataa gctttaaaat gattttctct gccttgagat ttgcatcaag    720
aaaaagcacc tctcttcacc tgaaagcttt gaagactaga gacacgcttt acacgtttta    780
acaagtatat tgagtccacg tttggtagca tcagttgttg agttaaaaag aaaattattg    840
catttgatct ggatggattt taaaagaata taatgttcaa tattaaaagg ataattcaca    900
tttgccacca taatgktctt ttttatgtaa aaagaagaac ttggagacat taacatgaaa    960
aagtctttta tcattagctc atgtatttga ggaagagcag ctgtcttttt atatgttttt   1020
tgacaaatca tattgtattc ttttgtacaa aaaagaacta cttgtattct agaagaaata   1080
tgaaatgctt aatttataag cgggctggag attttttcca atattgtttt ctttgaaaat   1140
gaaaggggat catctatttt agttttgggg tctgggaact ttttgaaaat ttaatttgtg   1200
gaccaatgtt ttgtgaaagc taaagagggc aggggttaaa atagggcttg aatttctcat   1260
tctgtataga ccagcaaact tccctgtgca aggcaagttt acatcacaaa tccaagaatg   1320
tttgcatcct aaatgctagt ttgcttcagc ccctagttaa cctcaggact tggtttgcat   1380
ataaaaggta gacagctgat atgttttcat gaataaatat tgtcagccag aaaaggttgg   1440
tgtcaggtaa tgcatatttt tttaagcttt gttttatatt tatttttcat ttagttttta   1500
ttgggaatgg ttttcaaaga actctcagtt ctgcctaggt gtttttgggg gagccctgtt   1560
ttccatagtg taattccatt taagaggttg tctaaaagtc tttttaatta atagaaagat   1620
tttaatatcc aagagtagtc aaattaagga tataaacgat ataaactttc cacaccttcc   1680
tgtcgtgaca gataaaagca cagaaaggac aacccttgaa atcatgtaac gttggtcatt   1740
tcaatatttt gtacctgttt taaattctgt tagtgtattt acttcattgt aaatattttt   1800
gagggtacct ttgtattttg cttttgacct tggttctgtg atttggatgt caacaacttc   1860
cctaaaaagc accagtgtgt taggttctaa tgtcatgacc caatttgtgt tattcatctt   1920
taatcctgtt ttcagtctct atgtgtacag cagtattttt aataaagaat kacagagata   1980
aaaaaaaaa                                                           1989

<210> 838
<211> 762
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (113)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (115)
<223> n equals a,t,g, or c

<400> 838
tgggaccttt ctccaggtta attagccatc tgtcctactc cagagttgac ctttggactc     60
cacagaagca cttacatgtg ggcccctcac cttaactatg ggggcaggag tnnangtccc    120
atgactgagg ctctggagct ggagacagtg aagttgatcc tgaataaatc agaggcaggc    180
tacagtccca aaccctgcta ggacctctag tcaagcagac aagttctttc ctcactccat    240
gctgcagggg cacaggccca gggtctggca acaaacagga gcagctgtgg tcactggggc    300
ctggagcctg ctggacatga catcatgcgg gcatgcccct actgtgtccc tctgtgctag    360
tagactgtgc aggtgcctgt gtactcggag caggagtacc agctttatct ccacgrtgat    420
gcttggacta aggcagaaac tgaccacctc tttgacctca gccgccgytt tgacctgcgt    480
tttgttgtta tccatgaccg gtatgaccac cagcagttca agagcgttct gtggaagacc    540
tgaggagcgg taytaccaca tctgtgytaa gyttgccaac gtgcgggytg tgcaaggcam    600
agaccttaag ataccaagta tttgatgytg ggcacgracg asggcggaag gaacagcttg    660
agcgtctcta caacccggac cccagagcag gtggcagagg aggagtacct gctacaggag    720
ctgcgcaaga ttgaggcccg gaagaaggag cgggagaaac gc                       762

<210> 839
<211> 1058
<212> DNA
<213> Homo sapiens

<400> 839
tgttccgggg gcgmgtggct gcagcggggc ccgcgtggtg cctcctgagg cggcccccgg     60
atgaagagat ctgggaaccc gggagccgag gtaacgaaca gctcggtggc agggcctgac    120
tgctgcggag gcctcggcaa tattgatttt agacaggcag acttctgcgt tatgacccgg    180
ctgctgggct acgtggaccc cctggatccc agctttgtgg ctgccgtcat caccatcacc    240
ttcaatccgc tctactggaa tgtggttgca cgatgggaac acaagacccg caagctgagc    300
agggccttcg gatcccccta cctggcctgc tactctctaa gcrtcaccat cctgctcctg    360
aacttcctgc gctcgcactg cttcacgcag gccatgctga gccagcccag gatggagagc    420
ctggacaccc ccgcggccta cagcctgggc ctcgcgctcc tgggactggg cgtcgtgctc    480
gtgctctcca gcttctttgc actggggttc gctggaactt tcctaggtga ttacttcggg    540
atcctcaagg aggcgagagt gaccgtgttc cccttcaaca tcctggacaa ccccatgtac    600
tggggaagca cagccaacta cctgggctgg gccatcatgc acgccagccc cacgggcctg    660
ctcctgacgg tgctggtggc cctcacctac atartggctc tcctatacga agagcccttc    720
accgctgaga tctaccggca gaaagcctcc gggtcccaca agaggagctg attgagctgc    780
aacagctttg ctgaaggcct ggccagcctc ctggcctgcc ccaagtggca ggccctgcgc    840
agggcgagaa tggtgcctgc tgctcagggc tckcccccgg cgtgggctgc cccagtgcct    900
tggaacctgc tgccttgggg accctggacg tgccgacata tggccattga gctccaaccc    960
acacattccc attcaccaat aaaggcaccc tgaccccaaa aaaaaaaaaa aaaaaaaaaa   1020
aaaaaaaaaa aaaaaaaaaa ctcgaggggg ggcccggt                           1058

<210> 840
<211> 1427
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (378)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1256)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1282)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1298)
<223> n equals a,t,g, or c

<400> 840
ggcagagcag caggcagcgc tctctgccct ctgctacatc cggagtcagc tggagaaccc     60
agagtccccc cagacctcca gccggcctcc actggccccc ctgagcgtag agaacatcct    120
gacccatgag cagcgctgcg cagcgttggt gagcgccggc tttgacctcc tgttggacga    180
gcgctcgcca tactgggcct gtaagsggac tgtggctgga gtcatcctgg agagggagat    240
cccgcgtgcc aggggccacg tgaaggagat ctacaagctg gtggctctgg gcaccggcag    300
cagctgctgt gctggctggc tggagttctc gggccagcag ctccacgact gccatggcct    360
ggtcatcgcc cgcagccntg ctgaggttct tgttccggca gctcctgctg gccacacagg    420
ggggccccaa gggcaaggag cagtccgtgc tggcccccca gccagggccc ggacccccat    480
tcaccctcaa gccccgcgtc ttcctgcacc tctacatcag caacaccccc aagggcgcgg    540
cccgtgacat ctacctgccc cccacctcgg aaggtggcct cccgcacagc ccacccatgc    600
gcctgcaggc ccatgtgctc gggcagctga agcctgtgtg ctacgtggcg ccctcgctct    660
gtgacaccca cgtgggctgc ctgtcagcca gcgacaagct ggcacgctgg gccgtgctgg    720
ggctgggtgg tgccctgctg gcccacctgg tgtccccact ctacagcacc agcctcatcc    780
tggtgccgcc ctggggcctc cctcccgtct ctgcaaggcc tcctttctcc gggcctttca    840
ccasgcggcc agggctgtgg ggaagcccta cctcctggcc ttgaagacct acgaggctgc    900
caaggctggg ccctaccagg aggctcgcag gcagctgtct ctcctcctgg accagcaggg    960
cctgggggct tggccctcga agccactggt gggcaaattc agaaactgaa gccagcctcg   1020
gcgggaccga ggtcccggag ccaagctgta cccctgctgg gggagtgccc tatctgagga   1080
gcgttgtggg gagaacatgg gttgtgcggg gtgaaactgg ggctggaggg aaggaggagc   1140
ctgctgtggt tgggaggcgg ctgctgcacg tttgggcttg aataaagaag tatttctggt   1200
aaaaaaaaaa aaaaaaaaac tcgagggggg gcccsgtacc caattcgccc tatagngagt   1260
cgtattacaa ttcactggcc gncgttttac aacgtcgnga ctgggaaaac cctggcgtta   1320
cccaacttaa tcgccttgca gcacatcccc ctttcgccag ctggcgtaat agcgaagagg   1380
cccgcaccga tcgcccttcc caacagttgc gcagcctgaa tggcgaa                 1427

<210> 841
<211> 1680
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (306)
<223> n equals a,t,g, or c

<400> 841
gccccggaaa cgtttctttc ctacgcagcc gctcctgccg ccgtggtcgc tggagctttg     60
cctctctagg ccggcagcgc ctctcctcca tggtcctgtc tgtcagcgct gttttgggag    120
cccgccggtg aggccgggcc acgctcagac acttcgatcg tcgagtctgt cactgggcat    180
ggcgggtcag ttccgcagct acgtgtggga cccgctgctg atcctgtcgc agatcgtcct    240
catgcagacc gtgtattacg gctcgctggg cctgtggctg gcgctggtgg acgggctagt    300
gcgaanagcc cctcgctgga ccagatgttc gacgccgaga tcctgggctt ttccacccct    360
ccaggccggc tctccatgat gtccttcatc ctcaacgccc tcacctgtgc cctgggcttg    420
ctgtacttca tccggcgagg aaagcagtgt ctggatttca ctgtcactgt ccatttcttt    480
cacctcctgg gctgctggtt ctacagctcc cgtttcccct cggcgctgac ctggtggctg    540
gtccaagccg tgtgcattgc actcatggct gtcatcgggg agtacctgtg catgcggacg    600
gagctcaagg agatacccct caactcagcc cctaaatcca atgtctagaa tcaggccctt    660
tggacatcct gctgacactt gggcccctta acaccttggg ctgctcagac cctccagatg    720
aggtccagcc cagatctgag aggaaccctg gaaatgtgaa gtctctgttg gtgtgggaga    780
gatagtgagg gcctgtcaaa gaaggcaggt agcagtcagc atgacagctg caagaatgac    840
ctctgtctgt tgaagccttg gtatctgaga ggtcaggaag gggacctctt tgagggtaat    900
aacakaattg gaaccatgcc actcttgagc cacaatacct gtcaccagcc tgttgtttta    960
agagagaaaa aaaatcaagg atatctgatt ggagcaaacc acttctttag tcatctgtct   1020
taccyccctg ggacagctgt tacctttgca gtgttgccga atcacagcag ttacctttgc   1080
artgttgccg aatcacagca gttctgttgg agaaacgctt ggtttccgga tccagagcca   1140
cagaaagaaa tgtaggtgtg aagtattagg ctgctgtcag ggagaggatg gcagatggag   1200
gcatcaagca caaggaaaat gcacaacctg tgccctgtta tacacacgtt catgtgcacc   1260
caagaaccta tgactttctt ccagttcctt ctaccaggtc cccatcctgc tgccagctct   1320
caacatagca ggccatagga cccagagaag aatcccagyg ttgctcaaag tctaaccatc   1380
ataaagacac tgcctgtctt ctaggaatga ccaggcaccc agctcccact ggactccaat   1440
tttttttcct gccttattta gaattctttg gcgggaaggg tatgatgggt tcccagagac   1500
aagaagccca accttctggc ctgggctgtg ctgatagtgc tgagggagat aggaatttgc   1560
tgctaagatt tttctttggg gtggagtttc ctctgtgagg ggcttgcagc tatccttcct   1620
gtgtatacaa atacagtatt ttccatgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1680

<210> 842
<211> 842
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (767)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (781)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (810)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (833)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (834)
<223> n equals a,t,g, or c

<400> 842
gcagctccct gcaaaaacag aaccaataaa agaacgagca gttcaaccag cacccaccag     60
gaagcccact gtaattcgaa ttccagccaa accaggaaaa tgtttacatg aggatccaca    120
aagtccacct cctctccctg ctgaaaaacc tattggaaac actttcagta cagtatctgg    180
aaagctcagt aatgttgaga gaactagaaa cttggaatcc aaccacccag gtcaaacagg    240
aggttttgtg cgagtacccc caaggttgcc accgagacct gtgaatggaa aaaccattcc    300
aactcaacag cctccaacca aggtgccccc tgagagacca cctcccccaa agctttctgc    360
aaccagaaga tctaatraga aactgccttt taatcgatcc tcttctgaca tggatcttca    420
gaaaaaacaa agtaacttgg caactggact ctcaaaagcc aagagtcaag tttttaaaaa    480
tcaagatccg gtgctacccc ctcgtcccaa accaggacac cctctctaca gtaaatacat    540
gctgtctgtg cctcatggaa ttgccaatga agatattgtc tctcaaaacc ccggagaact    600
ctcttgtaag cgtggggatg tacttgtgat gctgaagcag acggaaaata attacttgga    660
gtgccaaaag ggagaagaca ctggcagagt tcacctgtct caaatgaaga ttatcactcc    720
acttgatgaa catcttagaa gcagaccaaa cgatccaagc cacgctncag aagcctgttg    780
nacagtggtg ctcctcatgc tgtcgttctn catgattttc ccagcagagc aannggatga    840
tt                                                                   842

<210> 843
<211> 3333
<212> DNA
<213> Homo sapiens

<400> 843
gggctgcagg aattcattga cgacgacaac gttaacgtcg acccttttaa ttggacttcc     60
tactattcct gtcatgctga tattaggcaa gatgattcgc tgggaggact atgtgcttag    120
actgtggcgc aaatactcga ataaactaca aattttaaat agtatatttc cagggatagg    180
ttgtcctgtt cctcgaattc cagctgaggc caatccttta gcagatcatg tctctgctac    240
tcgaatcttg tgtggagccc ttgtctttcc tactattgct acaatagttg gtaaattgat    300
gttcagtagt gttaactcta atttacaaag gacaatcttg ggtggaattg cgtttgttgc    360
cataaaagga gcatttaaag tttacttcaa acagcagcaa tatttacgac aggcacaccg    420
caaaattctg aattatccag aacaagaaga agcataaaac tgacttctgg ttgttctgca    480
gttctctcat ccttatgaat ctgttgtgtt gttttgattc catcattaat gcacttgtgg    540
agacttgtga taagctgctg ctcctatatt ttttaagaaa tataataaag cacttagggc    600
aggggaaatc atctcggtaa tcatggaacc taaggatgtg atttgttttc attgtttgta    660
tgtactactt ttatggcagt catatgaacc attatcttag catggtaaac ctgggttttg    720
ttcatatttt ctccagacag aaatgcaaag atcaaactgt gcaaatatta aaaaaatgca    780
catgctgttt tattcaaatg cctcttttgt acatgttcat gtttagtgtt ttctcagaat    840
cagcaactca aggtactatg aggatttttc tcactgacat aatttgatta catactaaat    900
aagaggatat gttaatatga ggaaatgtaa attaaattag ttataaataa ataaccaaaa    960
atgtatgtaa acattcaaat gattatctga acaaatgaga ttttgtggtg ttttctttaa   1020
cccatgtgat gtcctccaaa atgtgtaggg taaaaattca cagggcttcc agatcacttt   1080
ttcaatatta aattttattt acataatgtt gacatctcat acttcatgaa gtaattttga   1140
ctcatgcagt cgtgtgtgtg tgtgtgtgtg tgtgtgtgta tttgtgtgtt tcagtgtttc   1200
atcaggtcct tccatctctg ggagtttttt caacccatat ttctagaaat tacagctgcc   1260
agtttatagt agtttgagca gaggatgatt tgcaaaaata aaaataaagt tattttactc   1320
tcctcttgca ttgattcagt tattgagata ttcgttgatc acctcctatt tcccaggcac   1380
tgtgcagagt gctgtaggac atagtggtga acaagacaga cttggtccaa gctcttacag   1440
agttgacagt ctagtttcag cacatagaaa accagcagtg aataaaccaa ggtgaggcct   1500
tgagctcttt gtttttatat taatgaggag aaaagtatga aaacaagaag tcttaagtaa   1560
atattgaggt cattgttttt ggcttaagtt tattatagaa aatcaacact aatgttttta   1620
gattttaatt gtcctattsa tgaggctagc accttaatca ctgtttagtt ttgtattcat   1680
ttttaaaagc aattattgaa gccattttca atagattggc cattttaatg ttcagcaacc   1740
tgaatggtta tttttgttaa ttaaaattaa atttttaaga gatattttca aaaccctatt   1800
tattttcttg ttcacagtaa tgcatgtcaa taataaatgt ttccccttac tgataagcgg   1860
ccactttagg agtgtagcaa atatagattg agctatgtta gtttgcaata atatatgtta   1920
actttagtaa ttaaagactg gtttctatag tatgaatgtc ttaattttga gttatatgat   1980
gtttatttga atgactgttg aacattcaaa tttgtattat ttggagatga agatttgact   2040
aacagtgagc cttattaaga acactactac agttctgaag gggaaatata acatctatgg   2100
ttatatattt taaaaactta gattataggc tgtaattata aaatatattg gcttttgttt   2160
tcaatgtgaa agatacatta aatggacaca tatcttgcaa aattttgttg tatagaacag   2220
tttttaggca gcctttacta aagttatgca aacacacagt tccccattta ctacattaat   2280
gcccttgaca gggagtagct gcttggtttt ataggtatta gggctcatga aggccgggga   2340
acaactctaa tccttttggg gcaggaggga gggttttttt agggttgcgg ggagggaact   2400
gcaagtgcct gaggaccaga gtggcctcta gccccgaatt gaacactttt aaacctaaag   2460
agccttatta ttattagctc gagaaatacc acatgccagt cttcccagga aggtgacctg   2520
cctgaccatg aagcaacaaa agagcatagg cagacttaaa gttggataga cctgggttca   2580
aatcatagtt cagctttcaa taactgtatg tatgattttg gctaaaggat ttgactttct   2640
ctcaactgca gttttcttaa tctttgaaat gcaaataatg tttatctcag aagactattt   2700
ctaggattaa ctgagagatt aaaggaacag cagcacttag gctcaaaatc gcccctacaa   2760
agcagtagtt gtttcttaat tgctaagtaa tctgtttgca ctctaggaaa agtaaatgga   2820
gaggtaaaag aaaggcattg gggacaaatg aaagagatga tgtagatttt tcggatgggt   2880
gggtatattt tattttccag tttattttca tatttcttta ctgtgttatt tctggaaact   2940
ttaatgtttt aaacctcttt tataaaattc aatgacgact actagaattc tattcttttc   3000
aaaagttaac ttatctccaa agtggctgaa aatattgttt accattacat gattatgaaa   3060
tgactgtgaa gaatataaaa ttaaacttag tgacttaatt agtcactgcc ttgctaactt   3120
tgctgtaatt tttttaaacg tcttgttttt aatatagcaa actatctcaa tactggctgg   3180
attaggttaa ataaagaatt tttatgttct ctaggtgtac tttgttaaat ctcaaaacat   3240
tctgtacata cataattttt tttaatcaca gttatcgaga tactagtttt tgtaagtaaa   3300
agtaatctga atttaaaaaa aaaaaaaaaa aaa                                3333

<210> 844
<211> 869
<212> DNA
<213> Homo sapiens

<400> 844
gtggggtagt tgaataaaat tgggcagcta aatttttcag ttccatgtgc ctcccaaata     60
aaaaacagaa aataagtagt ttttgtgaat tgacttgcag acaaagtaga aactgtgctg    120
catgatgtta ttttgtaaac agatgacatt ttctgaccag gcacatgcca tccaattttc    180
tgtcaatcac actgttgtat aaagcagcag aactgaaggg gaaaaatgat tgttgtatac    240
actgaattgc tttgcatggt ctcatttgag ataattgatg taagaatcct gactttttta    300
tatttggaaa catcaaataa aaatggaaaa aatgatcatg gctttaaaaa aaaaacaaaa    360
acacacacac atgaactcag atttgcaaac caggtttctg aaactttggg taaggtgtat    420
gcttttaact ttgaaatgta taaacaccca gcggaaacgt atacctttca gtgcatagtg    480
cattgtgtgc ttaccctggg ttgtttaaac ttgtgttcaa atattccccc tccaagtgaa    540
agcctgtcgg gaattccaca gtaacacctt tactgttctc ccattgatga tcatatacgt    600
tacctcttcc tagcggtaca tttgtatgat ccttactact ggaattaccg ggttaaaagg    660
aaatgcttac cactaagatg tcagtattct cctcatggat attttcartc tcaatgttgc    720
cagtctaata gtatagtatg tggttgcttt actgctgttc tccccacccc cgtggagttg    780
tgtcattatt ttaatgaatg tgagctcttg acttactcta gaattctaat acagatactt    840
tctgcactaa aaaaaaaaaa aaaaaaaaa                                      869

<210> 845
<211> 1889
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (57)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1295)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1370)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1844)
<223> n equals a,t,g, or c

<400> 845
aactaagtgg atcccccggg cacatnatgt tgatactgtt cgccatagcg ttgctgntgt     60
gtctgggcga actgacgtgc cagttcatcc tgctgcatcg catcgatttc atcatcgttg    120
tactgatcgc cagaatcgta ctgattgcgc tgggcttcac gggctttttc ttccgccgca    180
cgctgtgagg gcagcttaat accgtaagac gccagttcac gacgagttgg cacgcggata    240
cgtttcggtc gtggcaactg cggaccaatc ccctctttga cctgaggacg cggtccaccg    300
ctatttgcca gactgaagac tggcgcggca acggttgcgg cagccccgtc gccagtgtcg    360
cttttttcac gccagatgcc agcggggaaa cagcggcagc ggcttctact ggaggtactg    420
ctgcaacaga aggtgctttc agcgaagatt tgatcggttc tggttcttta accggttctg    480
gaatcggttg ataccaggcc gcaagttgtt cacgttcacg ggctcgcttc tcttcaactt    540
cttcaaagta gtaaagcggc ggacgcgcgg gttttgtctc ttctacaacg ggttcagctc    600
cacaacaggc tgctgttcaa cgggttgcgs ctgttggtac aacgggytct karcggctgg    660
ctgctgataa gtttgctcag tctggtatgt agactgtgra gcaaaagtgg attgctgctc    720
ttcggcttgc caggcgttac ctgccaccgg ttgttctggc gcaggggcat aatacggctg    780
ttgcgcaggt tgttcagctg caggtgcata atacggctgc tgcggctgta ctggttgttg    840
cagcggctca ttatattgca ctgcagctgc gcatattgtg actgctgtgg gtaaccttcc    900
ggtgcaggag caataaccgg ctctcccgtt tgtggacccg gtacaggctg ccaggctact    960
gtaggttgcg caggtggaac atcaacagag gcaacaggcg gcgtctgagt cacaggttca   1020
accggcgcag ccagctttgt gtcgccgtgg tagcagcagc tgctacagcg acaggttcgg   1080
taattggcgc accgtttaat aatggatcgt attcgtcata ttctggctgc gttgcacgrt   1140
tgcccgaaaa tagacgtcgt ccgggtcggc agccacaccg cgtgcagtgt aggtaatctc   1200
ttcgtcatca tcccatccgc tttaccggag aacaacgcag cgtctgtttg ccgccccatc   1260
ggattaatga atttttccgc caaccgtttt aacgnaccta agccgccgcg aagaatacgg   1320
gcacggcgtg attcatgctg tttgcccgtg attttcatct tcatactctn cgtcgtcttc   1380
atactcatct tcatcgaccc aggtatcatc gcgacgggta cgattactgg cgaaggtgag   1440
aatgtttaaa atccagccgc cgagtttttc agcaatgtca cccatgacca accggtgaac   1500
aacgtcaggc ccgctgccca aacgcagagc agcgcaatag ttcccccgct actgtgtagc   1560
agtggttgta rcstagtgct tagtaarctg ccmatgacgc caccggaggc aaaataccag   1620
ataycgtcag cgttgattgc cgccagacca caggaggtaa ggatgagcgc caaaacgcca   1680
atgatgcgta gcgaaacggc aaaataatca atgkmytcgt cgctggactg atgacgccag   1740
gcaaaccaac aaccgccgac aataatgacg ggaatggtgt aagccattca cgccaaaaat   1800
aaagaacagc gtatctgcca accacgcacc gggcatccca cctnaattat ggataggttc   1860
atgccaggcc gtttgcgacc agctggggt                                     1889

<210> 846
<211> 396
<212> DNA
<213> Homo sapiens

<400> 846
attaaatcaa atgatattga catattatga gggagaagaa gtcaatgctg gaaggattgg     60
gctaacgcta gtagtagctg gaatggtggg ctctattctt tgtggcttat ggctggatta    120
tactaaaaca tacaacttct tcatgactgg ttacctccct ttgggttttg aatttgctgt    180
tgaaatcact taccctgaat ctgaaggtac ttcatctggt cttcttaatg cttctgcaca    240
gatatttgga attytgttca cattggctca aggaaagctc acatcakact atggtcctaa    300
ggcagggaac atttwtctct gtgtctggat gtttatasgc atcatattaa cagcattaat    360
caagtctgat ctgcgagaca caacataaat atagga                              396

<210> 847
<211> 2044
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1980)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2035)
<223> n equals a,t,g, or c

<400> 847
ggaccgctaa gtccctgaca cctgacaaga aagtaaagcc aaaagtcagc tgaagataat     60
ggccatggag atgtctgtgg agagccgtaa aagccaatca tggctgagga tgcctgcaga    120
atctctgccc atgagaactc tgaggcctcc tttcctttgg ctgtggtaag ccctctggga    180
aaagagcagc tacccaccac cagccgcttg atggcattgg aacgaatggg aattgtaagc    240
gactatgaga aaatccgtac ctttgccgta gcaatagtag gtgttggtgg agtaggtagt    300
gtgactgctg aaatgctgac aasatgtggc attggtaagt tgctactctt tgattatgac    360
aaggtggaac tagccaatat gaatagactt ttcttccaac ctcatcaagc aggattaagt    420
aaagttcaag cagcagaaca tactctgagg aacattaatc ctgatgttct ttttgaagta    480
cacaactata atataaccac agtggaaaac tttcaacatt tcatggatag aataagtaat    540
ggtgggttag aagaaggaaa acctgttgat ctagttctta gctgtgtgga caattttgaa    600
gctcgaatga caataaatac agcttgtaat gaacttggac aaacatggat ggaatctggg    660
gtcagtgaaa atgcagtttc agggcatata cagcttataa ttcctggaga atctgcttgt    720
tttgcgtgtg ctccaccact tgtagttgct gcaaatattg atgaaaagac tctgaaacga    780
gaaggtgttt gtgcagccag tcttcctacc actatgggtg tggttgctgg gatcttagta    840
caaaacgtgt taaagtttct gttaaatttt ggtactgtta gtttttacct tggatacaat    900
gcaatgcagg atttttttcc tactatgtcc atgaagccaa atcctcagtg tgatgacaga    960
aattgcagga agcagcagga ggaatataag aaaaaggtag cagcactgcc taaacaagag   1020
gttatacaag aagaggaaga gataatccat gaagataatg aatggggtat tgagctggta   1080
tctgaggttt cagaagagga actgaaaaat ttttcaggtc cagttccaga cttacctgaa   1140
ggaattacag tggcatacac aattccaaaa aagcaagaag attctgtcac tgagttaaca   1200
gtggaagatt ctggtgaaag cttggaagac ctcatggcca aaatgaagaa tatgtagata   1260
atggactggg atatattgta tttctcatgt taaagcctct tcccttgaaa ttaaaaaaaa   1320
attttaactg ataaaactta gggcaacatt aattaatgta tattcttacc tgaattgtta   1380
tactttttga aaatcctgtg acttgcctgt ttctccccgc tccaacgaaa tcattaactc   1440
tcctaaaatg tgtttcattc tagtaagaaa acctcaaagg atattgtagg atataaatct   1500
tacttgaaaa catagctgtt gaaatgtttt ggccttttgg agtgggggaa ggacaaatct   1560
gatcctgtaa tctttttctt tccagtaatc ccttgtgtct gttgcatgag gacatggaca   1620
ataaagtagt atatgatcct cagatacagg gagaaggaca aggcatacag cttattgatt   1680
agagctggca agcatctgct cattatgttt ggaattgctt tctataagaa aattgcccac   1740
tactactaac ttgatcaaca atgaattcaa aatagttaac ctatgaaata acatcctctc   1800
aaatgtttgc tgatgaagta caagttgaaa tgtagttatt ggaaaagtct gtaacctgtg   1860
gatcatatat attcaaagtg agacaaaggc aaataaaaag cagctatttt catgaataga   1920
caaagttgrt ttcagggarg tattaaatta ttattctgca cccgaacmag ggamcrggan   1980
attwtttgca tctgtgggac atatatctgg gagttactat tactttactg gaagngccaa   2040
gggc                                                                2044

<210> 848
<211> 2124
<212> DNA
<213> Homo sapiens

<400> 848
ccgctctaga actagtggat cccccgggct gcaggaattc ggcacgaggt ggaagcagca     60
ccatcgggga gacaagcaat cgtagtcgag atcgggatcg gtatagacgg agaaatagtc    120
ggagccgaag tccaggtcgg cagtgtcgtc accgtagccg tagctgggat cgtcgacatg    180
gtagtgagtc gcgaagtcgg gaccatcgtc gtgaggatcg tgtgcattac aggagtcctc    240
cacttgccac tggttatagr tatggacaca gtaagagtcc tcatttcaga gagaagagcc    300
cagtcaggga gccagttgat aatctgagtc ctgaggagcg tgatgcccgc acagttttct    360
gtatgcagtt agctgcccga attcggcctc gagatctgga ggactttttc tctgctgtag    420
gcaaggttcg cgatgtacgt atcatytcag atcggaactc acgtcgttct aagggcattg    480
cctacgtgga attctgtgaa atccagtctg tgccactggc cattgggctg actgggcagc    540
ggttgctggg agtgcctatc attgtacagg cttcacaggc agagaaaaac cgactggcag    600
ccatggccaa caacctgcaa aagggcaatg gtggaccaat gcgcctctat gtgggttccc    660
tgcacttcaa tatcactgaa gacatgctcc ggggcatctt tgagcccttt ggtaaaattg    720
ataatattgt cctgatgaag gactcagata caggccgctc taaaggttat ggtttcatca    780
cgttctctga ttctgagtgt gcccggcggg ccctggaaca gttgaatggg tttgagcttg    840
ctggtcgacc tatgagggtt ggccatgtga ctgagcgact ggatggtggc acagacatca    900
cttttcctga tggggaccag gagctggatc tgggatcagc aggtggacgt tttcagctca    960
tggcaaaact ggcagaaggc gctggaatcc aactgccaag cactgctgct gctgctgctg   1020
ccgccgccgc cgcccaggct gctgccttgc aactgaatgg agcagttccc ttgggggccc   1080
tgaatccagc agctctgact gctctgagtc cagccctgaa ccttgcctcc cagtgtttcc   1140
agctctccag cctctttacc ccccagacca tgtaaatcag tggcacagta tactgcctcc   1200
ttgtgcctct ggatcctgcc acttcacatc tactcttcca tggccccatt tctccatttt   1260
gtggaccaag ccatcctgag ggcatggaca ttgtctctga ggaaattggg gccaccctta   1320
agataccaag aaaagctcct gcccatggtc ccactggaaa tggactctgc tgagcaaagc   1380
caccagttga agagaacaga atccacacct gcattgaata cctgtttctc catgtgtatc   1440
gtctctgaga ttaccttctt gccctttcca acaccttagt gattcctcaa tttctccccc   1500
attgggaagg ccatagggca ttaactgaag gaactgacct ctctcctttt cctgtacctt   1560
taacctttag tctgtcaagg aaaaccctta ggacctctga atcaagagga ctgagtttgt   1620
gggtgaacct tgaaggtgct ctttctgcta caagggccct gggagatagc atggacgtgc   1680
attgagaagc cagcctcaga ccttagcttg aagcagcttg aggccagacc tactgtagcc   1740
tcagcatctt gctaggaggc atggaagtga tctatcctgc caggaggcct cagagtgatc   1800
tgtcctgcca ggaggtgtga gagtgatctg tcctgtgagg catttagggg ctttcaggaa   1860
tttagtaaaa ggtggagtat gcctttccag tatcttccat cttcctttgt atacttgtcc   1920
ttcctcccat ttcctccctt tggcccgagg taggaggatg gagggaggct gctactctac   1980
cacttcctgt gtgcctctac tgtggcctca accctggcaa ttatagctac tcccatccct   2040
tacctgggca tgtgtgagcc cttctcactg gattttatac ccttgtgtct gtgtacctcg   2100
gccgcgacca cgctaagccg aatt                                          2124

<210> 849
<211> 1463
<212> DNA
<213> Homo sapiens

<400> 849
tttcgagctc tgcaccgagg agctgccctg gacttgagtc ccttgcatcg gagtccccat     60
ccctcccgcc aagccatatt ctgttggatg agcttcagtg cctaccagac agcctttatc    120
tgccttgggc tcctggtgca gcagatcatc ttcttcctgg gaaccacggc cctggccttc    180
ctggtgctca tgcctgtgct ccatggcagg aacctcctgc tcttccgttc cctggagtcc    240
tcgtggccct tctggctgac tttggccctg gctgtgatcc tgcagaacat ggcagcccat    300
tgggtcttcc tggagactca tgatggacac ccacagctga ccaaccggcg agtgctctat    360
gcagccacct ttcttctctt ccccctcaat gtgctggtgg gtgccatggt ggccacctgg    420
cgagtgctcc tctctgccct ctacaacgcc atccaccttg gccagatgga cctcagcctg    480
ctgccaccga gagccgcact ctcgaccccg gctactacac gtaccgaaac ttcttgaaga    540
ttgaagtcag ccagtcgcat ccagccatga cagccttctg ctccctgctc ctgcaagcgc    600
agagcctcct acccaggacc atggcagccc cccaggacag cctcagacca ggggaggaag    660
acgaagggat gcagctgcta cagacaaagg actccatggc caagggagct aggcccgggg    720
ccagccgcgg cagggctcgc tggggtctgg cctacacgct gctgcacaac ccaaccctgc    780
aggtcttccg caagacggcc ctgttgggtg ccaatggtgc ccagccctga gggcagggaa    840
ggtcaaccca cctgcccatc tgtgctgagg catgttcctg cctaccatcc tcctccctcc    900
ccggctctcc tcccagcatc acaccagcca tgcagccagc aggtcctccg gatcacygtg    960
gttkggtgga ggtctgtctg cactgggagc ctcaggaggg ctctgctcca cccacttggc   1020
tatgggagag ccagcagggg ttctggagaa aaaaactggt gggttagggc cttggtccag   1080
gagccagttg agccagggca gccacatcca ggcgtctccc taccctggct ctgccatcag   1140
ccttgaaggg cctcgatgaa gccttctctg gaaccactcc agcccagctc cacctcagcc   1200
ttggccttca cgctgtggaa gcagccaagg cacttcctca ccccctcagc gccacggacc   1260
tctctgggga gtggccggaa agctcccggg cctctggcct gcagggcagc ccaagtcatg   1320
actcagacca ggtcccacac tgagctgccc acactcgaga gccagatatt tttgtagttt   1380
ttatgccttt ggctattatg aaagaggtta gtgtgttccc tgcaataaac ttgttcctga   1440
gaaaaaaaaa aaaaaaaaaa aaa                                           1463

<210> 850
<211> 536
<212> DNA
<213> Homo sapiens

<400> 850
acccctgcag gtaccggtcc ggaattcccg ggtcgaccca cgcgtccgcc catttttccg     60
gttgataatg caatagataa tgkraaagaa attcaagttg cattgyytat cttaatggca    120
gcttatgcaa tggcggaagc gtttatgtca acaggagttg gagcttctct tatcctaatt    180
gcattaaaag taggaattac tgctaaaact gttgcagtta taggagctat tgtcacatca    240
atattatcaa tagcaactgg gacaagttgg ggaacatttg cagcctgtgc acctattttt    300
ttatggctaa atcatatagt tggcggaaat attttattga caacagcagc tattgcagga    360
ggagcatgtt ttggagataa tataggactt atttcagata ctacaatagt aagttctggt    420
atccaaaaag ttgaagttgt aagaagaatt agacaccaag gtgtatggtc agcattagtt    480
ttattatcag gaataatagt atttgctatt gttggattta catggattta cccttc        536

<210> 851
<211> 1837
<212> DNA
<213> Homo sapiens

<400> 851
ctggataacc taccagggat tcctttccca gtggacgctc acgacttatt tagatgtaca     60
gcggtgcctg gaatatttgg gctatctagg ctattcaata ttgactgagc aagagtctca    120
agcttcagct gttacagtga caagagataa aaagatagac ctgcagaaaa aacaaactca    180
aagaaatgtg ttcagatgta atgtaattgg agtgaaaaac tgtgggaaaa gtggagttct    240
tcaggctctt cttggaagaa acttaatgag gcagaagaaa attcgtgaag atcataaatc    300
ctactatgcg attaacactg tttatgtata tggacaagag aaatacttgt tgttgcatga    360
tatctcagaa tcggaatttc taactgaagc tgaratcatt tgtgatgttg tatgcctggt    420
atatgatgtc agcaatccca aatcctttga atactgtgcc aggattttta agcaacactt    480
tatggacagc agaatacctt gcttaatcgt agctgcaaag tcagacctgc atgaagttaa    540
acaagaatac agtatttcac ctactgattt ctgcaggaaa cacaaaatgc ctccaccaca    600
agccttcact tgcaatactg ctgatgcccc cagtaaggat atctttgtta aattgacaac    660
aatggccatg tatccgcacg tgacacaagc tgacctcaag agctccacgt tttggcttcg    720
agcaagtttt ggtgctactg tttttgcagt tttgggcttt gctatgtaca aagcattatt    780
gaaacagcga tgatataaaa agaaatactg tccctaccaa aaacaaatac ttttatgtac    840
attctgaatg ctttaagttc tgctagaatt attgagatat ttatacatgc agagttactt    900
tattaatatt tgtaattcat gcataagagt attttaatga tagttataac tgcagtattg    960
gctagcatat ggaaagaaaa cagctaacag ccaaactaaa atggctaaat tccagaggcc   1020
aaaagggaat attttgtaaa tatatgtaca tattcaggca agatatggtc tcccaagctg   1080
agttctagaa atgatgtttc tagacatttc taagtggtat tgttagtgct cacttggctc   1140
actcttctag gtttaagtta gcccagagat tgtatttact catggatcac tttatttatt   1200
tcacatttac tcagaatgat cctttgggtt ctataaggac ataaggtaca atttgccatt   1260
gtctctccat ttttaaaaac atacaagtca gtgtcagctt accaacatga cattttttca   1320
gtcagttgtg gtaggccagc cttgaagcca tcgcacagtc tagaaacttg tgtagctgag   1380
tgtgcagctc acctttaagg gtgaagttag gtaaaagcaa ttagcagagg cgttatctat   1440
gtgattatgt tgcttccttg tcagtatgtt gaattttata gccctttcaa tgaaataaaa   1500
aaaaaatttg tatattacca atgtttttag tttaaataaa gagtcaccct tactactgtt   1560
gaatttcatc ccaagtgtaa atcattctat aatggctgtg tctgttatag tatattacag   1620
taactgcatg tgtcaccaag tgttctatat caggctagga taacctagag gcagtaattt   1680
tttaaatgat aaaataaatc taatgaatat aaactctcat gataaaccta ttttttccat   1740
catcagcctt ttcaagtatt taaataaata actgctgtgt actgtgatct tgagttcttt   1800
tgtcatctaa agtaaatatt tctgtacaga taaaaaa                            1837

<210> 852
<211> 1517
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (144)
<223> n equals a,t,g, or c

<400> 852
gttgagtctt tgggtgtgct tttaatggtc tctctgcctc ttccttaggt gtcaggctgc     60
tctacctgtt tctagacgct cttcctttcc cccttccaaa cctcttttct tccttgctgc    120
tttcctatct tctgtggcta gganatcagg taatcaagcc tgtgttttct gtaatgagta    180
agtgggttgc cagcgaggtc tctgtggatg ctcctgtgag tcaagtgcat gagctttagt    240
gcatggactt tggggtcttg gttcccacag cttatatgtt ttgggggctg ctttcttgct    300
ctttacccac attctgtgtc atgagtgtgc cgggtaggtg gcctcctgcc cgatggaggc    360
tgagcatctt ggcagtgtcc atcatgcctt gcgtgtgcct ggcctctttg ctgcagatac    420
tatggacccg cagctcatcc cctgctcacc acctggcctc tccttttctc tgtgtgcaga    480
tctggcagtg tggtggggtt ctggaaacac acccatgttc ccatgttggc catgttttcc    540
ccaagcaagc tccctactcc cgcaacaagg ctctggccaa cagtgttcgt gcagctgaag    600
tatggatgga tgaatttaaa gagctctact accatcgcaa cccccgtgcc cgcttggaac    660
cttttgggga tgtgacagag aggaagcagc tccgggacaa gctccagtgt aaagacttca    720
agtggttctt ggagactgtg tatccagaac tgcatgtgcc tgaggacagg cctggcttct    780
tcgggatgct ccagaacaaa ggactaacag actactgctt tgactataac cctcccgatg    840
aaaaccagat tgtgggacac caggtcattc tgtacctctg tcatgggatg ggccagaatc    900
agtttttcga gtacacgtcc cagaaagaaa tacgctataa cacccaccag cctgagggct    960
gcattgctgt ggaagcagga atggataccc ttatcatgca tctctgcgaa gaaactgccc   1020
cagagaatca gaagttcatc ttgcaggagg atggatcttt atttcacgaa cagtccaaga   1080
aatgtgtcca ggctgcgagg aaggagtcga gtgacagttt cgttccactc ttacgagact   1140
gcaccaactc ggatcatcag aaatggttct tcaaagagcg catgttatga agcctcgtgt   1200
atcaaggagc ccatcgaagg agactgtgga gccaggactc tgcccaacaa agacttagct   1260
aagcagtgac cagaacccac caaaaactag gctgcattgc tttgaagagg caatcatttt   1320
gccatttgtg aaagttgtgt tggatttagt aaaaatgtga ataagctttg tacttatttt   1380
gagaactttt taaatgttcc aaaataccct attttcaaag ggtaatcgta agatgttaac   1440
ccttggtatt tagaaaatta aaaccttata atatttttct awmaaaaaaa aaaaaaaaaa   1500
aagggcggcc gctctag                                                  1517

<210> 853
<211> 1430
<212> DNA
<213> Homo sapiens

<400> 853
cagtctcagt tggagggctg atartaaacc ttattggtat ctgtgccttt agccatgccc     60
atagccatgc ccatggagct tctcaaggaa gctgycactc atctgatcac agccattcac    120
aycatatgca tggacacagt gaccatgggc atggtcacag ccacggatct gcgggtggag    180
gcatgaatgc taacatgagg ggtgtatttc tacatgtttt ggcagataca cttggcagca    240
ttggtgtgat cgtatccaca gttcttatag agcagtttgg atggttcatc gctgacccac    300
tctgttctct ttttattgct atattaatat ttctcagtgt tgttccactg attaaagatg    360
cctgccaggt tctactcctg agattgccac cagaatatga aaaagaacta catattgctt    420
tagaaaagat acagaaaatt gaaggattaa tatcataccg agaccctcat ttttggcgtc    480
attctgctag tattgtggca ggaacaattc atatacaggt gacatctgat gtgctagaac    540
aaagaatagt acagcaggtt acaggaatac ttaaagatgc tggagtaaac aatttaacaa    600
ttcaagtgga aaaggaggca tactttcaac atatgtctgg cctaagtact ggatttcatg    660
atgttctggc tatgacaaaa caaatggaat ccatgaaata ctgcaaagat ggtacttaca    720
tcatgtgaga taactcaaga attacccctg gagaataaac aatgaagatt aaatgactca    780
gtatttgtaa tattgccaga aggataaaaa ttacacatta actgtacaga aacagagttc    840
cctactactg gatcaaggaa tctttcttga aggaaattta aatacagaat gaaacattaa    900
tggtaaaagt ggagtaatta tttaaattat gtgtataaaa ggaatcaaat tttgagtaaa    960
catgatgtat tacatcatct tcaaaaatag atatgatgga ttctagtgaa gaccaaaatt   1020
acttctgttt actttctatc aggaagcatc tccattgtaa atatgtattt acatgtttat   1080
tacaaagacc caaatgaaaa atttttagtc cattttttgc atagcctaaa gataaaatag   1140
gaataaaagt tctatattta tggattttct gtatataaaa ctggtttcta attataactt   1200
aagtccatta agtaaaatct gtattgccac tttaaatgta aactaaatta tttgggagaa   1260
acttcaacca ctgatatgag ataagcaatg agaataggga agtgtataac atcacagttt   1320
ttgatgtatt acaaaaatca accactctat aaaataaatt ttttttactt ttggtaatat   1380
ttgcaaatga ataattaatt tattagggta aagaacttat actaagttgt              1430

<210> 854
<211> 1723
<212> DNA
<213> Homo sapiens

<400> 854
aaggtcaaca atagggtccc caaggccatc aatgccatca agcccttcta ccaagtccga     60
tggrcatcat cagtacaagg atatccctaa cccattaatt gctggaataa gtaatgtact    120
aaatacccca agcagtgcag cttttcctac tgcatctgcc ggaagtagtt ctgtaaagag    180
tcagcctggt ttgctgggaa tgcctttaaa tcagatcttg aaccagcaca atgctgcctc    240
ctttccagca agtagtttac tctcagcagc agccaaagca cagctagcaa atcaaaacaa    300
acttgctggt aacaacagta gcagcagtag caattctgga gctgttgccg gcagtggcaa    360
cactgaagga catagcactt taaacaccat gttccctcct actgccaaca tgcttctccc    420
aacaggtgaa gggcaaagtg gtcgagcagc actaagagat aagctgatgt ctcagcaaaa    480
agacgcattg cggaaaagaa aacaaccacc tacgacagtg ttgagtttgc tcagacagtc    540
tcaaatggat agttctgcag ttcctaaacc tggacctgac ttgctaagga agcagggtca    600
gggttcattt cccatcagtt caatgkctca gttactacag tctatgagtt gtcaaagctc    660
tcacttgagt agcaatagta ccccgggttg tggggcctca aatactgctt tgcttgctct    720
gctaaccagc tgcattttac agatcccagt atgaactcta gtgttcttca gaacatacct    780
ttaaragggg aagccgtgca ctgccacaat gcaaacacta actttgttca cagtaacagt    840
ccagtcccca accaccatct tgcaggttta ataaatcaga ttcaggctag cgggaactgt    900
gggatgctca gtcagtcggg catggcttta ggaaattcct tacatcccaa tccayytcag    960
tcaagaattt caacgtcctc cactccagtg ataccaaaca gcattgttag cagctataat   1020
caaacaagtt ctgaagcagg tatggtttta ttagaaaaaa gtacccaaag gtactaaact   1080
tttctacttt tttaaaaaat ttgtaccaaa atatttatta tgataagaaa tgatcctttc   1140
cccattgtga aattctcttc atttctttag tatttataat tttatttaca gaatgctagg   1200
gatttgtcta ttgggaagat taacagctaa gaggatttca tgtgtttcca ttatttgttg   1260
tcaatctgtg tcattttgaa tattgttcga ctttcacttg gttttataac cattggactc   1320
caaactgcaa aataagccat acgaggcagg gtttcctggt ttgtgagaca tgtccttggt   1380
ctatgccaat ataaaagcca tctccctagc ttttgtttgt attcaggtaa atgaagttta   1440
tcttggaaaa atccaaaaag gcaaaaataa atggattttt tttcttgctg ctgaacagaa   1500
gtaggtgaat ggataggaaa aggtaactag aagttgtacg aagtagaagg ctgtcttcta   1560
atgtgttttc ttatcctagt ttgctatcct tattatttgt ttgagaaaac tcaaaaatgg   1620
atattggcta ctccctttta aaaaaaaagc taataattta agctttctaa taaaaaaaag   1680
gcttgaaaac ctgaaaaaaa aaaaaaaaaa aaaaaaatta ctg                     1723

<210> 855
<211> 1655
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1378)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1444)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1521)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1606)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1648)
<223> n equals a,t,g, or c

<400> 855
agtctggagc cggcgcgtag gagcgggcgg ccgggctgtg ccctctccta ctcctcaccg     60
cgcgmgcggg gaaccagtar ccgcggctgc ttcggttgcc gcggtcggtg gtcgttatgg    120
attctccatg ggacgagttg gctctggcct tctcccgcac gtccatgttt cccttttttg    180
acatcgcgca ctatctagtg tcagtgatgg cggtgaaacg tcagccggga gcagctgcat    240
tggcatggaa gaatcctatt tcaagctggt ttactgctat gctccactgt tttggtggag    300
gaattttatc ctgtctactg cttgcagagc ctccattgaa gtttcttgca aaccacacta    360
acatattact ggcatcttca atctggtata ttacattttt ttgcccgcat gacctagttt    420
cccagggcta ttcatatcta cctgttcaac tactggcttc gggaatgaag gaagtgacca    480
gaacttggaa aatagtaggt ggagtcacac atgctaatag ctattacaaa aatggctgga    540
tagtcatgat agctattgga tgggcccgag gtgcaggtgg taccattata acgaattttg    600
agaggttggt aaaaggagat tggaaaccag aaggtgatga atggctgaag atgtcatacc    660
ctgccaaggt aaccctgctg gggtcagtta tcttcacatt ccagsacacc cagsatctgg    720
caatatcaaa gcataatctt atgttccttt ataccatctt tattgtggcc acaaagataa    780
ccatgatgac tacacagact tctactatga catttgctcc ttttgaggat acattgagtt    840
ggatgctatt tggctggcag cagccgtttt catcatgtga gaagaaaagt gaagcaaagt    900
caccttccaa tggcgttggg tcattggcct caaagccggt agatgttgcc tcagataatg    960
ttaaaaagaa acatactaag aagaatgaat aaatttacgt gatgagctct acaaggccaa   1020
aaattttttt tcttatctac ctgttatatt gtgctaattt tctatgtatg tgatgtgaaa   1080
tgaagactat atatatggaa tggaggtgac agaaagaaag aaattctttg tttgagggag   1140
acttcccctt tctggattgt atttgtagag tgttacgagt gtatcatgtg attatgcttt   1200
accggtataa gagattctgt tgtgattatt tgaatagttt tatattaata aaagaagacm   1260
aaatttttta aatgttagaa aaagcagatc tgtcattgca aagtaacaaa aattttaagc   1320
ttttaaaaat gtaagatttt tcgtattttt aaaatttgaa tctattttga gctttagntc   1380
agcagaatta aatttttact tgacattatc attaaaattg ctaggtatgg agaacaattc   1440
ctgntttatt ttgaacactg agaaagaggt aaacttttcc taaaacactt tatattataa   1500
accgaaaaat aaattgctag nttatatttt aagatattaa catcatattt tttaataata   1560
cctacatcaa atgggaaaat atctgaaatt tttttttcat tagcanggat ttttctacta   1620
gaaagtagtt taactacttt cattttanaa ccaga                              1655

<210> 856
<211> 1329
<212> DNA
<213> Homo sapiens

<400> 856
tttactccag gtagatttcc acaatatgca aagtggtggt ggggtcaaga cagatgacac     60
cagcacttta aactctttgt gtgggtatgc gtgggtgtat gtttgggaag aaaaacaaag    120
gtgcagacta tcttcctttt tttcttcttc agcctccatc cctggcctcc tcccctcaca    180
cacactggac ttggtacaaa atgtcggtgt ggtcctagat gaagcattgg ggtgggggag    240
ggagagggag ctttgtgtta agtgcctact ggaaatgcac tgtggggttt tttcctgtat    300
gggaaaccat ttatgccaag cttttcccca tttcccatat ttatctcatc tggttagctg    360
cctctgcttc cagctttgtg taattctctt tgccagctgc acaaagctga ttttttccaa    420
agtctaaaga ctgagctcac ctggctagat tgttgtgtgt tttgttgaat tttttcataa    480
tgtaatgccg tatttattgt ttttaaaatg aaaggaatac taataagtct taaaagttcc    540
ttcatgcata agattttttt ccagttactg ggcttaactg gtgtacatta attagatgtc    600
catactgtat tttgtttgca ttaagtaatt ttctttttga cttagtatcc ggcacacaaa    660
gtgggttagt actacagtat ttgcgttact ttaagtacta agtatgcagg tttcctggta    720
ccattgagtt gctgctatta aagctcacac acgaaatggc taaaagttac aagtgtgcaa    780
attatgactg cgtgagcctt agaaaataaa atgtataaag ggcaacacat gasctgtcaa    840
acagtgttag gagtgtgttt atatgtacag agttgtgcat agcaatcgtt ttatttaagt    900
tgatatgtag tctactcaca tttycattat ttagcaattt tgtacaaaaa tagcmattaa    960
tttgtaaaca ctgccagaat actttctagc tgctttgtaa ttttttaaga gtgttatttt   1020
gtttttgttt ttctgttctt tgttgtggct cttgttttca tttttgttgt acgtgtagat   1080
ctgtaaataa aattgcagta tttaaagctt aagctttcag gaaaaagaaa ataagaattc   1140
agtgtgtgca tgacaactcg tgtgtatgag aaggagggat atgaaggaag atggcttgca   1200
gagtaagtcg ggtggcaatt gtcagggtgt gatcttacca cttcaaatgg gtgtaatttg   1260
aataaatttt gtatggtaaa ggatcaataa aatgattttt tttaagaaaa aaaaaaaaaa   1320
aaaaaaaag                                                           1329

<210> 857
<211> 1592
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1218)
<223> n equals a,t,g, or c

<400> 857
tcgagttttt tttttttttt tttagtttaa aaaatattta ttatagaaat gtacatttaa     60
ttagttttaa ggaatgtacc tgaccacagt gttaatatat atttcttcaa atttgcaaac    120
tttacacctt taagatatct acaaagatga tagtttattt acaagtttta caagaaatga    180
tcacttcaca atactgttga cacagttacg attgaatctt cttctcactt tttatttcac    240
tctgtactta tagaaagaac agagagtatg ggtgaagttc catcccagtg ccagggaaag    300
cccgtagagc agaatcagag gtgcaaatgg atacagaaga attactgtat ttttcaaaaa    360
tggcaatgca ctgtatccca ggaaagttac atagatataa tagccaactg caaccaacca    420
taaggtattt ccaactaaat atccaataaa tgtgtctgtc aggataacat ggttgatgaa    480
aaaaagctgg ataaaatgca aaatgaccag gagtggataa aaagcattga gatgcacatc    540
aaaagcatag ccccattcca catcatagtc tctgctctgt cgtttcacta aatacttgtt    600
agagatgaac cacattaaag ttgctatcag aagaccaacg cctacacaat ctatgagtac    660
aacccaaagg agaagcttta ttgtctcaaa gaatcccatg tccagcacaa agccaaatcc    720
tatagtggac acacagagcc agatacttaa caggaccaag aaagcagggt catctctggc    780
ccactggtcc ttcgtctgtt ttcgataatg aaaatttctg taaactctct gtggggatgt    840
gaacaggtag agcatctgcc aggcagcaaa ttcaaagtcc atttgccgaa agcggaaaag    900
ccttctcaga tatttgtagc gtttcgctcc ggctgtgtgt cttgccgcat ccctggaatt    960
caagactccg ttcccctgca ctaaggaatt cactgaagta ctcggtaaca tcttcctaga   1020
tggaagaaaa acatttcttt tacacgtatt ctgaagaaac wtttggctac cgacactcct   1080
cttctgagtt atttggcagg gaggtcactt tccatgttct tcccaaccct agagaaaggc   1140
caggagtcaa aagcaaatgc agttagttct gaggcgggtc ttggggcttg ggaaccgcag   1200
actgcaacct caggcaangc aacagcccac ccttctgaat cacctaataa cacttatcca   1260
ggggcagcta ccattacaga gacagggatg atgtgactgc cccatgactc cgaggatagt   1320
gatagagcca agattggaaa tctgactcga aattccgtgc tcttaaccac caagctttta   1380
agaaaatgcc taagaaagca gtttcagccg gttagaacag tgttactgaa gaggtcaaat   1440
aaatggccta ttcacacaga tcagcgcact gccagcaagc ttctcggtca ctagaatgag   1500
attaaaaaac caagaaaaac tccgatccct agtgttttac atccggaata gttcagcaga   1560
gggagcggta gcgtcggagt ccagtccaac cg                                 1592

<210> 858
<211> 681
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (518)
<223> n equals a,t,g, or c

<400> 858
ggctttacgg ctgcgagaag acgacagarg gggagacatg gccggcgaag gagatcagca     60
ggacgctgcg cacaacatgg gcaaccacct gccgctcctg cctgcagaga gtgaggaaga    120
agatgaaatg gaagttgaag accaggatag taaagaagcc aaaaaaccaa acatcataaa    180
ttttgacacc agtctgccga catcacatac atacctaggt gctgatatgg aagaatttca    240
tggcaggact ttgcacgatg acgacagctg tcaggtgatt ccagttcttc cacaagtgat    300
gatgatcctg attcccggac agacattacc tcttcagctt tttcaccctc aagaagtcag    360
tatggtgcgg aatttaattc agaaagatag aacctttgct gttcttgcat acagcaatgt    420
acaggaaagg gaagcacagt ttggaacaac agcagagata tatgcctatc gagaagaaca    480
ggattttgga attgagatag tgaaagtgaa agcaattngg aagacaaagg ttcaaagtcc    540
tttgagctaa gaacacagtc agatggratc cagcaagyta aagtgcmaat tyttcccgat    600
gtgtgttgcc ttcaaccmtg tctgcmgttc mattagaatc cctcaataag tgccagatat    660
ttccttcaaa acctgtctca a                                              681

<210> 859
<211> 1659
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1544)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1626)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1649)
<223> n equals a,t,g, or c

<400> 859
gggaagtggt ggtaagggaa tgactgtatt tccactagca tattatgcct gcatttcttg     60
ctttagattg tgaaagtcac catggatatc catttgaatg aaatggctgg agacatcttg    120
gtttttctga ctggccagtt tgaaatagaa aaaagttgtg agttactttt tcagatggca    180
gagtctgttg attatgatta tgatgttcaa gataccaccc tccgatggct tgttaatatt    240
gccgtgttat ggatcaatga caacagatca acagaggarg atatttttgc caccaccacc    300
tggaattara aaatgtgtca tatccaccaa tatttctgca acgtctttga caatagatgg    360
aatcagatat gtggtagatg gtggcttcgt gaagcagtta aatcacaacc ccagattagg    420
gttggacatc ctggaggtgg ttccaatttc aaagagcgag gcattacagc gaagtggccg    480
agctggcagg acttcttcag gaaaatgctt tcggatctat agtaaagatt ttkggaacca    540
gtgtatgcct gaccatgtga tccctgaaat taagagaact agtttgacat ctgtagttct    600
gaccttaaag tgccttgcca tacrcgatgt cataaggttt cccyatttgg atccacctaa    660
tgagagactt attttagaag ctcttaaaca actttaccag tgtgatgcta ttgacaggag    720
tggccatgtc accagattgg gtttgtctat ggtggagttt cctttgcctc cacatctgac    780
atgtgcagta ataaaagctg cttccctgga ttgtgaagat ctactacttc caatagcagc    840
aatgttgtct gtggaaaacg tcttcattag acctgttgat ccagagtacc agaaggaagc    900
agaacagaga catcgagaat tggcagctaa agctggagga tttaatgact ttgcaacttt    960
agctgtcatc tttgaacaat gcaaatcaag tggagctcca gcttcatggt gccaaaaaca   1020
ctggattcat tggaggtgct tattttctgc atttcgtgtg gaagctcaac ttcgagaact   1080
aatcaggaag cttaaacagc aaagtgattc ccaaaagaga cctttgaagg ccctaaacat   1140
gaagtactac gaagatgtct ttgtgcgggc tatttcaaaa atgtagctcg aagatctgtt   1200
gggagaacgt tttgcacaat ggatggtcgt ggaagcccag ttcacattca tccttcctca   1260
gcacttcatg aacaggaaac caaacttgaa tggatcattt ttcatgaggt attggttacc   1320
accaaagtct acgcaagaat tgtatgccca atccgttatg aatgggtaag agacttgtta   1380
cccaagttgc atgaatttaa tgcacatgat ttgagcagtg tggcccgacg tgaagtgaga   1440
gaagatgcaa gaaggagatg gacaaataag gaaaatgtaa agcagctaaa ggatggaata   1500
tcgaaagacg tcttaaagaa aatgccaaag aagaaatgat gacnaatcca tatctgatgc   1560
mcggggytcg tttccttgag agaaagccwc agaggacccg gaaccagtga ccacaccgga   1620
aagggnaacc aggctaaggg gggggaannc cccccaatt                          1659

<210> 860
<211> 1949
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1905)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1907)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1924)
<223> n equals a,t,g, or c

<400> 860
cggtccggaa ttcccgggtc gacccacgcg tccgcccacg cgtccgccct tctcccgaga     60
gttgcgagaa actttccctt gtccccgacg ctgcacgggc tcgggtaccg tggcagccgc    120
aggtttctga accccgggcc acgctccccg cgcctcggct tcgcgctcgt gtagatcgtt    180
ccctctctgg ttgcacgctg gggatcccgg acctcgattc tgcgggcgar atgcccctgg    240
gacacatcat gaggctggac ctggagaaaa ttgccctgga gtacatcgtg ccctgtctgc    300
acgaggtggg cttctgctac ctggacaact tcctgggcga ggtggtgggc gactgcgtcc    360
tggagcgcgt caagcagctg cactgcaccg gggccctgcg ggacggccag ctggcggggc    420
cgcgcgccgg cgtctccaag cgacacctgc ggggcgacca gatcacgtgg atcgggggca    480
acgaggaggg ctgcgaggcc atcagcttcc tcctgtccct catcgacagg ctggtcctct    540
actgcgggag ccggctgggc aaatactacg tcaaggagag gtctaaggca atggtggctt    600
gctatccggg aaatggaaca ggttatgttc gccacgtgga caaccccaac ggtgatggtc    660
gctgcatcac ctgcatctac tatctgaaca agaattggga tgccaagcta catggtggga    720
tcctgcggat atttccagag gggaaatcat tcatagcaga tgtggagccc atttttgaca    780
gactcctgtt cttctggtca gatcgtaggr acccacacga agtgcagccy tcttacgcaa    840
ccagatatgc tatgactgtc tggtactttg atgctgaaga aagggcagaa gccaaaaaga    900
aattcaggaa tttaactagg aaaactgaat ctgccctcac tgaagactga ccgtgctctg    960
aaatctgctg gccttgttca ttttagtaac ggttcctgaa ttctcttaaa ttctttgaga   1020
tccaaagatg gcctcttcag tgacaacaat ctccctgcta cttcttgcat ccttcacatc   1080
cctgtcttgt gtgtggtact tcatgttttc ttgccaagac tgtgttgatc ttcagatact   1140
ctctttgcca gatgaagtta tttgctaact ccagaaattc ctgcagacat cctactcggc   1200
cagcggttta cctgatagat tcggtaatac tatcaagaga agagcctagg agcacagcga   1260
gggaatgaac cttacttgca ctttatgtat acttcctgat ttgaaaggag gaggtttgaa   1320
aagaaaaaaa tggaggtggt agatgccaca gagaggcatc acggaagcct taacagcagg   1380
aaacagagaa atttgtgtca tctgaacaat ttccagatgt tcttaatcca gggctgttgg   1440
ggtttctgga gaattatcac aacctaatga cattaatacc tctagaaagg gctgctgtca   1500
tagtgaacaa tttataagtg tcccatgggg cagacactcc ttttttccca gtcctgcaac   1560
ctggattttc tgcctcagct ccattttgct gaaaataatg actttctgaa taaagatggc   1620
aacacaattt tttctccatt ttcagttctt acctgggaac ctaattcccc agaagctaaa   1680
aaactagaca ttagttgttt tggttgcttt gttggaatgg aatttaaatt taaatgaaag   1740
gaaaaatata tccctggtag ttttgtgtta accactgata actgtggaaa gagctaggtc   1800
tactgatata caataaacat gtgtgcatct tgaacaattt gagaggggag gtggagttgg   1860
aaatgtgggt gttcctgttt tttttttttt tttttttttt ttagntntcc tttttaatga   1920
gctnaccctt taacacaaaa aaagcaggg                                     1949

<210> 861
<211> 1750
<212> DNA
<213> Homo sapiens

<400> 861
gattcggcat gaggcacgca gccaacatgg ctccagtgga gcacgttgtg gcggatgctg     60
gggctttcct gcggcatgcg gctctgcagg acatcgggaa gaacatttac accatccggg    120
aggtggtcac tgagattcgg gacaaggcca cacgcaggcg gctcgctgtc ctgccctacg    180
agctgcggtt caaggagccc ttaccggaat acgtgcggct ggtgactgag ttttcaaaga    240
aaacaggaga ctaccccagc ctctctgcca cggacatcca agtgcttgca ctcacatacc    300
agttggaagc agagtttgtt ggggtgtctc acctaaaaca agaaccacag aaggttaagg    360
tgagctcatc gattcagcac ccagaaacac ctctgcacat ttctggtttc catctgccct    420
acaagcctaa acccccacaa gaaacagaaa aaggacactc agcttgtgag cctgagaacc    480
tggaatttag ttccttcatg ttctggagaa accctttgcc caacatcgat catgaactgc    540
aggagctgct gattgacaga ggtgaggacg ttccaagtga ggaggaggag gaggaagaaa    600
acgggtttga agacagaaaa gatgacagcg atgacgacgg gggtggctgg ataaccccca    660
gtaacatcaa gcagatccag caggagctgg agcagtgtga cgtccccgag gacgtgcrgg    720
ttggctgcct gaccacagac ttcgccatgc agaatgttct gctgcagatg gggctgcacg    780
tgctggcggt gaacggcatg ctgattcgtg aggcccggag ctacatcttg cgctgccatg    840
gctgtttcaa gacaacgtct gacatgagcc gagtgttctg ctcacactgt gggaacaaga    900
ccctgaagaa agtgtccgtg accgtcagcg acgacggcac cctgcacatg cacttctccc    960
gcaaccccaa ggtgctgaac ccccgcggcc tccggtactc gcttcccact cccaaagggg   1020
gcaaatacgc catcaacccc catctcaccg aggatcagcg cttccctcag ctgcgactct   1080
cccaaaaggc caggcagaaa accaacgtgt tcgcccctga ctacatcgcc ggggtgtcac   1140
cctttgtcga gaatgacatc tccagccgct cagctaccct gcaggtccgg gacagcacct   1200
tgggagctgg gcggagacgc ttaaatccca acgcttccag aaagaagttt gtgaagaaaa   1260
ggtgaagagc gagttcccgc aggcaaattg gatgggcgtc tggccgccgt ggagttccgg   1320
tgacccattt ccccagccgt gtcgtctcca ggaccacccg atggaaataa caggcgggct   1380
tcacggtgcg gctctgtccg cccatgcccc gctgggtctg cagggaactg gactgtccca   1440
tggcctgtga gcaccggagc gcctggctgc ctgccaagga agtgcaattg cataaaaaca   1500
gaaagaacaa cgccctggag ccaatcttca agaaaggaat ttccaaagga taatattttt   1560
ctaataaatg cggctgcaac ctcctgtgca tttaattaaa taggccaaat ttttgctgct   1620
taggtcatct caaggctgat acttgagctg tgtgcccaga gatcatgcat ttagatttat   1680
atttttgcca gaaaatacaa ggttataata aaactaagaa ctaccaaaaa aaaaaaaaaa   1740
aaaaaaaaaa                                                          1750

<210> 862
<211> 1205
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (294)
<223> n equals a,t,g, or c

<400> 862
gaaggactgc acagaggcct tccttgtgag ccgcctctga actagctgca ctaggacagg     60
tgccaaatgt gcatcgtgtg ggttttgccg tctgtttggc aggcggctgc ttttccctgc    120
tgcttggtgg cttctctgcc ctcgctcttg agtgcacctt cggttcctcc cacagttggg    180
caaatgagcc aaactacctt catggggtac tgaccgatct ctccttgact taggctcaag    240
ctgggccatg ccagagtgga gccagtgaac actcagctcc agaagggccc aggncactga    300
gtccgtggta attctgcaag gctgggtcag agccagggtg tggtgccact agggttgtct    360
ccgtagccta tttctatagc tggccactgg ggttggcagt gaacagtaat cacacttgtt    420
ttgtgaattg aacaggaaga tcccagtgtc tgagtgaact aacagtcctg ctttcagcca    480
ccatttgcac aagacaccca gcactgaaag tcccgctgcc aggagcaagg gatcctttgg    540
aagcacccgc cctttgtgcc ttgttggggg aaaccggtga cgcagaagtg agtgtggata    600
caccagagtt tgcattggaa ggaatgagtg tcacgtgggg agggaagggg ccagtggacc    660
ttttgtaagc tttccactca ataaaatgaa cctgtatggc aaatacttga aatggaactc    720
actccttcca ctttccccct ttcttctgtc ccaggaaata gatcatcttt tgaaaagact    780
cttgtctagg aaaagttgtg tccttttcct aatttaacgt gttctttctt aatgaagttt    840
taatttattt ttgttgagat tttgctagat ggcttttgca tcccctgtag atggtgagtg    900
ttggcggtga tgtccrtctc ggcgttcgga ggccccacgg tcccgaggct gggccggggc    960
cccccagggt ggctgtgctg ctgcctgtag gagggtgcgg gttgtgctgt catcctcggg   1020
tttgcacgcc cttttttagg agcctgtgga catctgtggt tttgtacttt ggggcttcag   1080
gggaggtgtt taactttcta gtgattgatg attgtcaggt tttgaaatac caaagctttt   1140
ttgttctgtt tttaaataaa tatctttcaa actttcaaaa aaaaaaaaaa aaaaaaaaaa   1200
aaaag                                                               1205

<210> 863
<211> 471
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (65)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (393)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (442)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (471)
<223> n equals a,t,g, or c

<400> 863
ctgtaacctt ttcacgcgct atctgctaaa aatgttgccg atgtgaagta aacatggatg     60
tagtnacctg acgtgccagg cgaggagtga gtgtgaaagc gragaagsag gaaactgccg    120
cgaccatgaa agackttgcc ctcaaggsaa aagtctctac agcgaccgtc tcccgagcat    180
taatgaatcc cgataaagtc tcccaggcca cccgtaatcg ggttgaaaaa gcggcccggg    240
aagtgggtta tttaccgcag cctatggggc gcaacgtcaa gcgtaatgaa tcccgcacca    300
ttctggtgat tgtcccggat atctgcgatc ccttctttag cgaaattatt cgcggtatcg    360
aagttacggc ggcaaatcac ggatatctgg tgntgattgg cgactgtgcg catcaaaatc    420
agcaggaaaa aacctttatc gntttgatca tcaccaagca aattgattgg n             471

<210> 864
<211> 2297
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2115)
<223> n equals a,t,g, or c

<400> 864
gcggccgcgg gagcttcccg ggcctggccg tggaaccagg cagcaacctg gacatggaag     60
atgaggagga ggaagagctg accatggaga tgtttgggaa cagctccatc aagtttgagc    120
tggacatcga gcccaaggtg ttcaagccgc cgagtagcac agaggccctg aatgacagcc    180
aggagttccc cttccccgag acgcccacca aagtgtggcc gcagacgagt acatcgtgga    240
gtactcacta gagtatggct tccttcgcct gtcgcaggcc acccgccagc gcctgagcat    300
ccccgtcatg gtggtcaccc tggaccccac gcgggaccag tgcttcgggg accgcttcag    360
ccgcctgctg ctggatgagt tcctgggcta ygatgacatc ctcatgtcca gcgtgaaggg    420
cctggccgag aacgaggaga acaagggctt cctgcggaat gtggtgtcgg gcgagcacta    480
ccgctttgtg agcatgtgga tggcgcggac gtcctacctg gccgccttcg ccatcatggt    540
catcttcacg ctgagcgtgt ccatgctgct gcggtactca caccaccaga tcttcgtctt    600
catcgtggac ctgctgcaga tgctggagat gaacatggcc atcgccttcc ccgcagcgcc    660
cctgctgacc gtcatcctgg ccctcgtcgg gatggaggcc atcatgtcgg agttcttcaa    720
cgacaccacc accgccttct acatcatcct catcgtgtgg ctcgcggacc agtatgacgc    780
catctgctgc cacaccagca ccagcaagcg gcattggctg cgggaacccc aggggctggg    840
cctggcaggg tgggacctgc agccccgatg ccctcacccc gccccgcagg ttcttctatc    900
tctaccactt cgccttctat gcctatcact accgcttcaa tgggcagtat agcagcctgg    960
ccctggtcac ctcctggctc ttcatccagc attccatgat ctacttcttc caccactacg   1020
agctgcctgc catcctgcag caggtccgca tccaggagat gctgcttcag gcgccgccac   1080
tgggccccgg gacccccacg gcgctgcccg atgacatgaa caacaactcg ggcgccccgg   1140
ctacagcccc tgactctgcc ggccagcccc ccgccctggg ccccgtctcg ccyggggcca   1200
gcgggagtcc cgggcctgtg gcagcggcgc ccagctccct ggtggccgcg gcagcctcag   1260
tggcagcagc tgccggtggt gacctgggtt ggatggcaga gaccgctgcc atcatcacag   1320
acgcctcctt cctgtccggc ctgagcgcct ccctcctgga gcggcgtcca gccagcccgc   1380
tgggccctgc tgggggcctc ccccacgccc cccaggacag tgtccccccg agtgactccg   1440
cagcttctga cacaactccc ctgggggctg cggtaggcgg gcctagcccg gcctccatgg   1500
ccccaacgga ggcgccctcg gaggtggggt cctgagccgc acagctgagc cgcctctgac   1560
ccctgctggc tgggcctgac cttcccgagc ccgtgggggt gggggaggcc agccacctcc   1620
ttcctctggg actgcccagc ctgtgtcggg ggctttcagg gtttcgtggg gtttgcccgg   1680
aaggcggctt tcctccccct ggtgtgaggt cgcgcccgag gcttgtaccc gctagtgagg   1740
tgtttgagct ggtcagcaag gagagggggt ggggttccgc ggaaggttct ggaggggtct   1800
tggtaggtct gcagtgaacc gtcctgagga tggagtgggg tcccatggtg caggtctctg   1860
agcaaggcgg aggtgtggag gagaggccgg cttggggtgg ggcctcgcgc cctagtgccg   1920
gccggcctca gcccggctct gcctggtgct ccctgcagtg ccttctccat ggccccgccc   1980
tccccgcgtg tgcgccaggc ctggggtccc cgggagagca gagcttgcgc ctcgggcata   2040
gggacgtggg gtgcaggcgc caacatcagt ggcagcagcc agggccgtgg tccagtccca   2100
ctcggggatg gagtnggccg gcggccaaac cagtcactcg gggaggaatg cggaggagcg   2160
ctcattccat tctatttaat tgcagtgtac aaaattgtgt ttgtatatag aataaactgt   2220
ctgttgacag cgaaaaaaaa aaaaaaaaaa aaaaaaaaag ggcggccgct cgcgatctac   2280
ggacgcgtgg gtcgacc                                                  2297

<210> 865
<211> 2892
<212> DNA
<213> Homo sapiens

<400> 865
cttccttgaa ttctttgcgt ggggcctgtt gacaactcca atgttgactg ttctacatga     60
aacattttct caacacacat tcctcatgaa tggtctcatt caaggtgtaa agggcctgct    120
ctcttttttg agtgccccac tcattggtgc cctgtctgat gtgtggggga ggaagccctt    180
tctcctcggc actgtattct ttacctgctt cccaatccca ctgatgagga tcagcccatg    240
gtggtatttt gcgatgattt ctgtgtctgg agtcttctcg gtcacgtttt ctgttatatt    300
tgcctatgta gctgatgtca ctcaggagca cgagcgaagt acagcttatg gatgggtctc    360
agccaccttt gsggctagtc ttgtcagcag cccggccatt ggagcatatc tttctgccag    420
ttacggagac agcctcgttg tgctggtggc cacagtggtg gctcttctgg acatctgctt    480
catcttagtg gctgttccag aatctctgcc tgagaaaatg agaccggttt cctggggagc    540
tcagatttct tggaaacaag cagacccttt tgcgtcgttg aagaaagttg gaaaagattc    600
tactgtctta ctaatctgca tcaccgtgtt tctttcatac cttcctgaag ctggacagta    660
ttcaagtttt tttctctatc tcaggcaggt cataggtttt ggatctgtta aaattgcagc    720
attcatagct atggtaggaa ttctgtctat tgtggctcag acggcctttc ttagcatctt    780
gatgagatca ttaggaaata agaatactgt cctccttggc ttgggcttcc agatgctcca    840
gttagcctgg tacggttttg gatcacaggc ctggatgatg tgggcagcag ggaccgtggc    900
tgccatgtcc agcatcacgt ttccggcaat cagtgccctc gtctctcgga atgcagagtc    960
agatcagcaa ggagttgccc aggggatcat aactggaata agaggactat gcaatggcct   1020
ggggccagca ctgtatggct tcatattcta catgttccat gtggaactga ctgagttggg   1080
cccgaaattg aattctaaca acgttcccct gcagggagct gtcatcccag gcccgccgtt   1140
tttatttggg gcatgtatag tccttatgtc ttttctggtt gccttattca ttcctgaata   1200
cagtaaagcc agtggagttc aaaaacacag taacagcagc agcggcagcc tgaccaacac   1260
cccagaacgg ggcagtgatg aggacattga gccactactg caagacagca gcatctggga   1320
gctctcttca tttgaggagc ctgggaatca gtgcactgag ctgtaaactc ggcagaaagt   1380
gggattctgc atacgccatc tctgagagcc atggagggag ccacacccct ggtgacttca   1440
tggtgctgga tgggagacgc tagcggcatc cttcagggcc aagtttgata aataccaccg   1500
ccatcattct gctcatcctc ctcctgtttt tttttttctc ttacattctt tttttttttc   1560
ctgtttatac attagaacaa gataagattt gaaatacttc cttgcaaata atgtgcaact   1620
cccaaggtga aactcaaata gaaaaagtca tctctctggt agaaaggatg gctttcctgt   1680
aatgactata gagtaagagt ggcagcaatc tttccatgcc cttttcagca gaaggcacag   1740
aacagtagcg ggactgccat ctctggcaag atttcaggta aagaatctct tcttaatttc   1800
taccttcctg tttctctgaa tcagcccata ggtgttgatg agtggccact cttaaagagt   1860
cactcagtat cagggatcta ctgtctttgt tcaaaggtca aataaaaacc tagtctcctt   1920
ttattctact ttctattctt agctagaatg aaactcagca tatatacact tctggacata   1980
ataatattga atagtaatta cctttactag atgaaagaaa ttttcattac aaacttaaat   2040
catgtaaaac tcaacaactc agattcctgg acctggtgtc ctggttgggt ccaaggtgat   2100
tttacagaag aaaaaaacaa ctcaagcatt ctggtggcaa catagagatt gtaggctgct   2160
tctaagaaag ttattaacaa tttggaaatt cctaagtagg atgagagtta gtaactggat   2220
acgagtgaag tttatatcca agttcagact caaaggcatt attatgattt gcttcttccc   2280
atgtcttcca tgtcctgctt ctcaaagttt ttctcatcca tcacactcct gccttaactg   2340
ctctgagtat gcatttgttt tcaattcatc tttatttcaa tctgtttaac ttttgaatcg   2400
catgggaata cgcacattaa gttcctttct aaaataaggt tttatgaagc tgagtttcac   2460
gataagtgtc ttgctatttt ttgagatgtt ttatggacaa agaaaacttt acagatttat   2520
atgtattttg ctgcaccagt aaatggacca ttaactaggg cccaccttta acagagcacc   2580
cctttgaaag ttttataggt atgaaatata tgtagatatt tgtaaagggt tttaattttt   2640
tttttgatgg ggtgctgtgt aaatcttgta tttataaatg taatgaaggt attgacagaa   2700
aaaaatatat acaactttta taaaggattg tgtactgact gaatacattt aaaagaaaat   2760
atattttgaa acctgttctg ctatgaacag agataacata tctttttact atgctattgg   2820
tttttaggtt aagcttccta atgcataata aatttacagt ggttamtttt aaaaaaaaaa   2880
aaaaaactcg ag                                                       2892

<210> 866
<211> 756
<212> DNA
<213> Homo sapiens

<400> 866
gcgtgcacca gccagacctc atgaactcag gaaggtgctt gtccaggagt tcctggttgc     60
tgtgcccttc acaggcaaag actgcattyc ttcctcagct gycagtgagg tgctgssagg    120
attccctgta gaactktcag gccagtttat gaactggttg gmaccygtgt cctcytcctg    180
gcccaggmag gagaaccatg agcaggcaga aggagacttt gcaaagtgcc ttccccagca    240
tgtgtgccct ctgcccttca gagcctgcag atakkagggg tggcaaggac actgttctca    300
atgagcagaa cctccaagac acccaaagct gcctgtttgc cacctggccc tatgcctgcc    360
ccgttttctc cctcaaggcc ttcacccatg ctagggcagt cacctggaat gtcctttcca    420
ttacccctgc tgtaatgccc agcacagaac ttgatggcag gcctttgcat ggtagcctga    480
agcgatctca cccttctaac tgggtttgcc acaggcacac tggctcatgc ttacctgtgc    540
tgcctgtggt tatagttatg cgaattgtgg ttttacatcc ctaaaacaga agggcacggt    600
gtccagggga tagcacccag cccaacttca gtgtagacct gagctgggag ggaacctgtt    660
agtctcccca cctcttccct gaagagacag gcacccctcc cagccgtggt caacggaggg    720
agtggcactt ctgccttgag tccccagggg aaaaaa                              756

<210> 867
<211> 933
<212> DNA
<213> Homo sapiens

<400> 867
gtgctttccg gcgctctgcc ttccggtgcg tcgtttacgc cagtttgaac caaagacgcc     60
caaggttgag gccgagttcc agagcatggg gtctcggttg tcccagcctt ttgagtccta    120
tatcactgcg cctcccggta ccgccgccgc gcccgccaaa cctgcgmccc cagctacacc    180
cggagcgccg acctccccag cagaacaccg cctgttgaag acctgctgga gctgtcgcgt    240
gctttctggg ttggggctga tgggggcggg cgggtacgtg tactgggtgg cacggaagcc    300
catgaagatg ggataccccc cgagtccatg gaccattacg cagatggtca tcggcctcag    360
cattgccacc tggggtatcg ttgtcatggc agaccccaaa gggaaggcct accgcgttgt    420
ttgaaagtac caccagtgaa tctgtcttct gtctctgtcc ctttccccgt gacacacaga    480
gcaggcatgg aatttaatgg gtgttctgga cagacacttg tacatggaca gacatcacta    540
ctgtggatac tacaagactg aaaagaaaat cgtatgttgt cattctctgg ctatggagtg    600
tttgtggcct tcacagattt cacaggaacc aataaatccc tcagagaagt aaaaaaaaaa    660
aaaaaaaggt ckttattaam ggcgcagcta tcccttagta aggtatttac ttgactgcgt    720
cgttaaagcg tactggaact gggtcgactt atcttagaac cctttcactg gtatacaagc    780
ccagatcttc taattgccca agcaagggcc ttccggtaaa cgggtgtttg gtcgaaaaac    840
cccggttttt ctttggtggc caacatgctt gcatgtcgcc aattgcggtc tgatctgggg    900
tagctacacc tttaccttaa aaaaagcggt tat                                 933

<210> 868
<211> 553
<212> DNA
<213> Homo sapiens

<400> 868
gctagggcta ctgctcgtct tcctgggcat cctttgggtg aagatgggca agccctcagc     60
gccgcagagk sggaggacra catgaagtta ttgccagtgg actgtgagag aaaaacagat    120
gagttctgtc aggccaagca gaaggcagcc ttgctggagc tgctgcatga actctacaat    180
ttcctggcca tccaagctgg taattttgag tgtggaaatc cagagaatct aaaaagcaaa    240
tgcattcctg ttatggaagc ccaagaatat atagccaatg tgaccagcag ctcctccgcc    300
aagtttgaag ccgcactgac ctggatactg agcagtaaca aggacgtggg catctggttg    360
aaaggagaag accagtctga attggtgacg actgtggaca aggtggtctg cctggaatct    420
gcccaccccc gcatgggtgt tggctgccgc ctgagccggg ccttgctcac tgctgtcacc    480
aacgtgctca tcttcttctg gtgcttggct tttttgtggg ggctcctaat tctcctaaaa    540
tatcggtggc gaa                                                       553

<210> 869
<211> 1356
<212> DNA
<213> Homo sapiens

<400> 869
tcgacccacg cgtccggttt tttatgcayt wgagtcttgg atcaagtayg atgtacaaga     60
acgycagaaa tacttagcac agytactwaa yagtgtrmga ttaccattgy tgagtgttaa    120
gtttctcact agactatatg aagcaaatca tcttattcgt gatgatcgca cttgtaaaca    180
tcttttgaat gaagccctaa agtaccactt tatgcctgaa catagactct ctcatcagac    240
agtcttgatg acacgacctc gctgtgctcc caaagtactt tgtgcagtag gagggaaatc    300
tggactcttt gcctgtttgg atagtgtgga gatgtacttt cctcagaatg actcttggat    360
tggtttggca cccctaaaca ttcctcgcta tgaatttgga atatgcgttt tagaccaaaa    420
agtatatgtt ataggtggta ttgcaactaa tgtgcgtcct ggcgtcacta tcagaaaaca    480
tgaaaattca gtggaatgct ggaatcctga tacaaatact tggacttctc tagagagaat    540
gaatgaaagc cgaagtactc ttggagtagt agtacttgca ggagaacttt atgccttagg    600
tggttatgat ggacaatctt atttacaatc tgtagagaag tacattccca aaataagaaa    660
atggcaacct gtggcaccaa tgacgacaac aagaagttgt tttgctgcag cggtattgga    720
tggaatgata tatgccattg gtgggtatgg tcctgcccac atgaacagtg tggagcgtta    780
tgatccaagt aaggactcct gggagatggt tgcatccatg gcagataaaa ggattcactt    840
tggcgtgggt gtcatgctag gctttatttt tgtggtgggt ggacataatg gagtctcaca    900
tttgtccagc attgaaagat acgatcctca tcaaaatcag tggactgtgt gtagaccaat    960
gaaagaacct agaacaggag ttggtgctgc tgtaatcgat aactaccttt atgtcgtcgg   1020
tggtcactca gggtcttcct atctgaatac agtgcagaaa tatgatccta tctcagatac   1080
gtggctggat tcagctggca tgatatactg tcgctgcaac tttgggttaa ctgcactttg   1140
acaaatgtga actctcggaa atagtatggt ggtgaaactt gtactgcatg aacatccgga   1200
tggcccagtt ttctgaaacc cacaagctgc attgctttct ttttaacttg aagtagcatg   1260
aaggctcaaa agttttgttg ggtactttta attgagaagt agttttggtt gctcttgatt   1320
acacagtaaa tcaataatca aaaaaaaaaa aaaaaa                             1356

<210> 870
<211> 703
<212> DNA
<213> Homo sapiens

<400> 870
gcaaacattg gacatctctg acatattttt tctcgttttc agcttttcgg atgatccctt     60
atcccttgga aaaggggcac ctattttatc cttacccaat ctgtacagaa acagcagacc    120
gagagctgct tccatctttc catgaagtct cagtttaccc aaagaaggag cttcccttct    180
ttattctctt tactgctgga ttatgttcct tcacagccat gctggccctc ctgacacatc    240
agttcccgga acttatgggg gtcttcgcaa aagctatgat tgacattttc tgctcggcag    300
agttcaggga ctggaattgc aagagtattt tcatgcgtgt tgaagatgaa ctggaaatcc    360
ctccggcacc tcaatctcaa catttccaaa actgaactca tcacccctct tcccccacca    420
ccaaaactgc tcctcctcct gtattcctra cctccgccat ccaccccgtt gctcaagcsg    480
gaaactcggc agcccttcca aactcttccc tctctcactc cccacatccc atcgtctcgg    540
ccttcacaat ctgtcagttc taacctccta agcaactagg ccttcagtaa atgtgattca    600
cctcttcttt ccctcctttt cccaaaagca tccctcttag tctaggtcct ttgttggttt    660
cttggcttga acttctggcc ataagtctta acttggggct ccc                      703

<210> 871
<211> 1239
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (456)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (457)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1128)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1166)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1186)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1206)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1218)
<223> n equals a,t,g, or c

<400> 871
gttggtgctg ccatccacta aggagacctt caggttcaag ctaactccaa atcctacgaa     60
gcccttctct tctgctctgt ggctggcagc ccagctcttg taacaaaggc atggaaattg    120
acagcagcta tagccacaat ctgaggaatg gcagacaaga aacagcagag taggcctcaa    180
ggagtcactg aagaacccag ggctcctctt tttagctcag agccatttag ctgaaattga    240
tgagtggatg gtctttaagt cattctccct tgattggtca gtggcctgtc acagataact    300
ggcttgggag ctgcctccat gctcctgagg gtcttcttgg tggttgtcac acagtgtggc    360
tgctgagtgg ggacaggctc cttgtgaatg gtgtgctctg tctaacctct ctcattcccg    420
ccctcccgac tcaccgacgt gcatgctgcc cacatnnccc ctgcccaaga caccccctgc    480
acccccatct gctcccctcg tgggcagcag gtgcctatgc cttgtctacc tttctgctcc    540
tcatccctac agtgagggag actctgatgt ggactcggag ctggaggacc gtgttgacgg    600
ggtcaagtcc tggttgtcaa aaaacaaggg accttccaag gcagcttctg atgatggcag    660
cttaaagagt tccagcccca ccagctactg gaagtccctt gcccctgatc ggtcagatga    720
tgagcacgac cctctcgaca acacctccag accgcgatac tcccacagtt atctgagtga    780
cagcgacaca gaggccaagc tgacggagac taacgcatag cccaggggag tggttggcak    840
ccctctcacc ccagggcctg tggctgcctg ggcacctctc ccaggaagtg gtggggcacc    900
ggtctccccc acccgactgc tgatctgcat gggaaacacc ctgaccttct tctgtcaggg    960
gcactttyca ggctatgggt gkctgatgtc tccacgtgga agaggtgggg gaaagaggag   1020
kttctgaaga gaactttttg stcctytgkc tcaaaawgsc agactcttgg cttctacccc   1080
tgtgtcaccg tgggccagtg gcaaggtggc ctggcactgc atggaagnca agcacgttga   1140
ccttccttct cagcttccct gctcanggac ggtgggacag ggttgnctac tgggacactc   1200
ttaagntgct tgggtccntt ggggaaggat tgggggaag                          1239

<210> 872
<211> 1429
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<400> 872
tgnccaggta actttacact tacaatgaat tcatggattt tgttagcagc attggctttc     60
tcaaaaggac aaactcaata tcgttataaa atataattcg tgatcacaaa ttatacaaaa    120
atcagtagaa acagtttttt atgttcagat taaaaaaaaa aacttgggat aattttarat    180
ttacaraaaa gttgcaaaga tacatggaga gcttctgtga ccactcaccc agttccccca    240
gtgttaacct tttatttaac catgaagcat ttgtcagaag ctaagtaacc agcaatggca    300
attactatta acggaacttt gactttattt ttcagattgt actagttttt taattaatgt    360
catttttctt ttccaggatc caatctagga taccacactg aattagtcgt catgcctaat    420
tagcctctgg tctgtgatag ttccacagtc tttctttttc ataaccttga cagttttgag    480
gagtactggt caggtgtttt gtagaatatt cctcaatttg ggtttgtctg atgttttcct    540
catggttaga gtggggttat agatttttag gaagaatacc agaggtgaag gtccttctca    600
ctgcatcatg tcaggagtta catgctatca gcttgatggt gtattaactt tggacacttg    660
gttaaggtag tgtgtgttgg ttttttgctg ctgaaaatta ctgttatttt ccctttccat    720
acttctgttc tttggaaaac agtcactaag tccagtcatg ggaggtggtg ggtgggaaag    780
attacattca accccctgga agtgggaata tccatatgta gtatttggaa tttttctata    840
tggaaaattt gtttctccct cccaccctaa tttgtttaca tcagtatgga ctcatgtata    900
ttttgtattt tgggtaacac agtatttatt ttgttgctta agttgtccag cttggctatt    960
aggagttctg ccaggttggc tactatgtcc ctttgatgtg cccatccttt tgatttttga   1020
gcacttctta ctttctggca ctacaagatg ctccaggttc atcttggata ttccctgccc   1080
caaccctaga atccctagaa tcaacccctg ctccaaagag ccctggttcc ttttgttgga   1140
gaatcatact tagaaaccaa gatctgggca ttagatgtgc ttgttgctac tgggatgtca   1200
ctgtttgtag cagagttgag aaatatgtat gtatattaat ccatgcatat gtacacatct   1260
ataattattt atgtgtgtac aaagctaaac atgagtttgt actgccgtct tcaactcaaa   1320
atttgtccca aaattttgtg gcatatgttt agattttaaa gttgatattt tccctattga   1380
cagaataaac tcattaaaag agcaaaaaaa aaaaaaaaaa aaaaaaatt               1429

<210> 873
<211> 805
<212> DNA
<213> Homo sapiens

<400> 873
tttttttttt tttttttttt ttttctttta acgttataat tttatttcaa agaaaacaga     60
aacagaacaa aaacaacctt tgcatttgag ggaggagatt attttacagt tttggaaaag    120
aataagaaca attgtatcag gaaacaaatg attatgacag aaactcgcat ccgacagctg    180
cagtgaatcc acgaggacac agaccatgct ggtggccaca gcagggccac aggtgaatcc    240
acaaggaaac acagaccatg ctggcagcca cggcagggcc acagggcacg gtctccatgt    300
gttaatgttt aatgtcagca ttttcatatg gacagaaatc acgaagaaat cctgcaaaaa    360
tggcatcaat atgaacaaac ccttgttata aaaagcaaaa tattgatagg aacaatatct    420
tccagcgtgt gcgtttcaca tttaggcttt actgtatgaa actaagtcaa aattagaagc    480
actggctatc tccaccgaca tatattttaa ctgaatataa acttcaaggc ttttcttaac    540
cataggctta agaggatttc ttttatgcag aatgtgacca gagcaacaaa tacacctaaa    600
ctgtttgaag atgggaaatt tatacatgaa atgagctagc aggcttcctt tggtatgggg    660
acactgttat tctaaaatta aaaaaaaaaa attgaatgga agtggactgc ttcaagatgg    720
taacacttgt agctgcaatt tttagcccag tagagaatga aatggaaagg cagctacatg    780
ctgactgcac aagcaggtgc acccc                                          805

<210> 874
<211> 2229
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (262)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1358)
<223> n equals a,t,g, or c

<400> 874
agctcactaa gggaacaaag ctggtgctcc accgcggtgg cggccgctct agaactagtg     60
gatcccccgg gctgcaggaa ttcggcacga gaggaagcgg cgcacggtgg cctcgggtgc    120
cacctgctgc aggtcggcca tcttgaagtc gtaggtggct gtgtagccca cgttggccag    180
tgtggtctca cacatgtaga aagtcccgta agagccgtgg aagagctcct ccacgaactc    240
cagcaggccg atggcgatct tngcccgcca aggcgagcac agcaccgact gcacctacgg    300
gcgcgactgc agggccccgt gtgacaggct catgaggcag tgcaagggcg acctcatcca    360
gcccaacctg gccaaggtgt gcgcactgct acggggctac ctgctgcctg gcgcgcccgc    420
cgacctccgc gaggagctgg gcacacagct gcgcacctgt accacgctga gcgggctggc    480
cagccaggtg gaggcccatc actcgctggt gctcagccac ctcaagactc tgctctggaa    540
gaagatctcc aacaccaagt actcttgatg gggcagtgag gggcctggcc acccttcctg    600
gagctggcca ggtgccaggg tccarccctc cctcaaggaa tcctgtcaga agatgtgaaa    660
tgcaactgtg ttgcaaaatc actcccctac cgtcagggct ctggattcca gcaccacaga    720
catgagaccc cagctcggag caaaggcgga catggacatc ccggcaggag agtcctccaa    780
gggggtttgt tactctgaag aacgtaatgt caataaacag cttttatgta atgcccaggg    840
ctgagcaccc tgagccccca tcgatgctgt gtgtgggacc cttcgccccg ctgtggatcc    900
acccagccca ggcactcagg ctggggttga gcccctgaat ccttcctggc gargyrgccc    960
tcargtgtta gtccaaggtg aggtctattg cagagtgcct gcccttcaac ccacacacac   1020
ctctgaagcc gccagggcag ttccccaaac acagcggctt ctgaaacagt caatgaccag   1080
taccccccaa acctgggctg tgcacaacag accaagaaaa aggtgttcca gtaagaaaac   1140
agatatatgc ggtattttaa aaactgattt tacaaaatcc agccatgaga tgtacaactc   1200
attccctagg aaacagccca ggaatggcca tcttctccag ccccgtacgc tctccccagt   1260
agcccagggc acccagcaac catcccctag gagaacaggc aaggaccctc gtgggaagat   1320
cccaccacag caacaccttt cttcagggcg ggctctgntc cgcaatgtgt gagtcaagac   1380
aatccattcc attcaagacc aatttactct caaattttgc caacacagaa atattatcct   1440
taaagaaatg tgcatttaaa tcttttaatt cacttcatcc tgtattttaa aataaatgtt   1500
ttccatatag attttcccct tgggggggaa aagaattcag ggtcttaggt tccaggcagt   1560
tcaaaaacag ccacgcggtt cttttttctc caccagaata ccacaatagc agaacttaag   1620
aatcgggata tgaaaaggga ggcgtggtcc tggcagtggc ccctggccgg caggaataca   1680
cagcaacacc caggcagggg cagcggctgc ccccatgcca gcctgcccat ccctttattc   1740
cagccagcct cctggcacag ggctgggccc acatcctggc ctctgcatct ggatcagggc   1800
tggtgctggt cagcctggtc actctggcca gtgctcacac tggaagtcca tcacaggcga   1860
agtcacctcc ttcccgtgtt aaataacaag aatgccaaca ccccacgcac gtgtcatctc   1920
cagtgagcag acgtccaggc ttcccgaagc ttcctggctg gaaaccgcgc agggccggca   1980
gcgccctctc caccaaggga cacagcagcg gcgcctcctc cgcggcccgg gcccccatcc   2040
cgcggctcgc gctgccagga cgccccaggt cggagcctgc ccccaccccg cacccggagg   2100
ccagcagccc agtcccctag gccgcgcagc gccagcgaga gcgaggctgc agggcgaggc   2160
ccggtgaggc gctcgagaac tggccgggag gagaagtcag gcggacgcgt gggcggacgc   2220
gtgggtcga                                                           2229

<210> 875
<211> 633
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (593)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (606)
<223> n equals a,t,g, or c

<400> 875
ttcctttttt tttttctcca gatcccacgt ttcgctcttg ttgcccacag ctacttactt     60
cattccccat gggtcacgtc attcatccac attaaccaat ttcctcactc caagctcttt    120
tctagagata atctccagtc cctgtgcaga aactgtcatt gcactttctg ctgaaatggc    180
agtttcttct cagcaaggtg agattatgga atccagaatc ttttttcagg ggtcacatgc    240
ccatttcccc acttgcatga atgtcgacac tgcagccaca gttttggccg taaatgtgaa    300
tttggcaagt aaccactgtt cccagggaaa tgtcccaatc agaagaagat tatctgggac    360
actgatactg acagggagat gggacattct gagggacccg gaggcagggt gccacctcct    420
caacttccct gagggctgcc taggaatctg tttcctcttc attctggaat tattcttcct    480
ctttatgggc tgaccaaaaa catgggaacc ttcacaaagt ccactgttaa cagcttttwt    540
ttttgtggar gtkgarggac atggaggacg tttttaaggc caaagtttat ttngagttgg    600
ggacantttt gtggtttttt ttttttgagg aag                                 633

<210> 876
<211> 1177
<212> DNA
<213> Homo sapiens

<400> 876
ggcagagctg acgttccccc cagcttagac cctgagtcgt tttcccccgt ttcccggctg     60
aattaggttc ttcttctcca caggtgtgtg cagtggcctc agggatccgg aaagtctagg    120
actgaacttc tcctaacatc cagtaatggg gacctggaac ctgggcgtac tagagtgccg    180
cgcgtagggc tccaggtcgc tggcttctgc gctttcttcc tctccaaagt tgagtatctc    240
ctatctgtgt cctcatacat actgccgcct gaggtgccat ggcccccaag ccgggggccg    300
agtggagcac agccctgtcc catctggtgc tgggagtggt gtctctgcac gcagccgtga    360
gcacagccga ggcaagtcga ggggctgctg ctggcttcct gctccaggtc ttggctgcca    420
ccaccacgct ggccccaggg ctgagcacac atgaagactg ccttgctgga gcctgggtgg    480
ccaccgtcat cggccttccc cttctggcct tcgatttcca ctgggtgaat ggggaccgct    540
cctctgccaa cctgctcctg ggaggaggca tggtgctggc agtggctggc ggccacctcg    600
gccctgaggc cktctgtggc tggtcaggca atgctgttgg tggtcgcagt gaccatcctc    660
attgtagctg tcttcacggc caacacttat gggatgtggg ggggggcgat gctgggtgtg    720
gcaggcctcc tgagccggct ggaggaggac aggctgctgc tgctaccgaa ggaggatgtc    780
tgtcgctggg ccttggctgt aggcagctgg gcttactgcc gggccctgca tacacagcgc    840
ctccagtggg agtgacagtt ggatacagcc aggcagggtt tctgccctgc cgaacacttt    900
ccctcccacc tgcctgctcc tggcgccttc tccctagggg tagactcttc tgcctactga    960
agtgggtttg ctgcacattg actggtcagg ggcagagtct gggtgctgtc ctttggccac   1020
gtgtggggac ttgtctagac cagaatgaaa gggacagggt cccagacacg tttgggggtc   1080
ctgattctgg gctggacacg gttgtggatc cagagaagag gcctagtctc caataaatct   1140
taggaatttt gcaggaawaa aaaaaaaaaa aagtttt                            1177

<210> 877
<211> 755
<212> DNA
<213> Homo sapiens

<400> 877
ggtaacaaca aaatttgttc ggacatcaac aaataaagta aagtgtcctg tatttgttgt     60
taggcatagc atggaaaacc tttttgaaaa gaataaaatc cgagcatcca tatcttataa    120
gtggactcca gaaggaagac gcttggtcac tggagcttct agtggggagt ttaccctgtg    180
gaatggactc actttcaatt ttgaaacaat attacaggct cacgacagcc cagtgagggc    240
catgacgtgg tcacataatg acatgtggat gttgacagca gaccacggag gatatgtgaa    300
atattggcag tcgaacatga acaacgtcaa gatgttccag gcacataagg aggcgattag    360
agaggccagg tttatacaca atataccatt ttctgtagtc cctattgtca tggttaaatt    420
attctctaag tgtattctgg gtgcagagat gcatgggctc tgtcagtttc tgggaaactt    480
tctgcaccct ataaacacaa tatttttctt tgttttcaca cattcaccat tttgctggca    540
cctttctgaa gtagtgttgt cccggtatca gcctttgcaa tatgttagag atgtactgtc    600
tgccgcattt tgcactggtt ttctcttttc atttatgatt aataatgtgt atacgttatt    660
cctttttatt atctactgtg taagacaaga atatttcatt ccaaataaag aattcagtct    720
ttaattatgc aactgaataa aatctaaagc ctaaa                               755

<210> 878
<211> 556
<212> DNA
<213> Homo sapiens

<400> 878
gtttagcaca aagaaaagcc atcttggtgc aaagaggctt taaattacta tggactggca     60
gtcaatcaaa atccaggaat tgatgtctga tgatcagaga gaagcaggtc ggattccacg    120
aacaatagaa tgtgagcttg ttcatgatct tgtggatagc tgtgtcccgg gagacacagt    180
gactattact ggaattgtca aagtctcaaa tgcggaagaa ggttctcgaa ataagaatga    240
caagtgtatg ttccttttgt atattgaagc aaattctatt agtaatagca aaggacagaa    300
aacaaagagt tctgaggatg ggtgtaagca tggaatgttg atggagttct cacttaaaga    360
cctttatgcc atccaagaga ttcaagctga agaaaacctg tttaaactca ttgtcaactc    420
gctttgccct gtcatttttg gtcatgaact tgttaaagca ggtttggcat tagcactctt    480
tggaggaagc cagaaatacg cagatgacaa aaacagaatt ccaattcggg gagaccccca    540
catccttgtt ggtttt                                                    556

<210> 879
<211> 608
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (561)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (596)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (602)
<223> n equals a,t,g, or c

<400> 879
aaaaatggga tgaaccttgg tataaccaaa aaacagaaca tcaaagaaat agcagtaaga     60
ttctgagatt tatttcagac ttccttgctt ttttggttct ctacaatttc atcattccaa    120
tttcattata tgtgacagtc gaaatgcaga aatttcttgg atcatttttt attggctggg    180
atcttgatct gtatcatgaa gaatcagatc agaaagctca agtcaatact tccgatctga    240
atgaagarct tggacaggta gagtacgtgt ttacagataa aactggtaca ctgacagaaa    300
atgagatgca gtttcgggaa tgttcaatta atggcatgaa ataccaagaa attaatggta    360
gacttgtacc cgaagaccaa caccagactc ttcagaagga aacttatctt atcttagtag    420
tttatcccat cttaacaact tatcccatct tacaaccagt tcctctttca gaaccagtcc    480
tgaaaatgaa actgaactaa ttaaagaaca tgatctcttc tttaaagcag tcagtctctg    540
tcacactgta cagattagca ngttccaaac tgactgcact ggtgaggtcc cggcanccaa    600
cnggcacc                                                             608

<210> 880
<211> 528
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (511)
<223> n equals a,t,g, or c

<400> 880
agattttttt atatgtttat tttatctctg tcttttctga cagtctttat atttgcattc     60
gttatcaccc acgtcattct tcgttcacag caaacaggat tcctaaatgc ccttaaggac    120
agtcctgcaa gcgtcctgga ggctgtggtg tgcttcttct ctgtctggtc catcgttggc    180
ctctcaggat tccacaccta cttgatcagc tccaaccaga caacaaatga ggacattaaa    240
ggatcctggt caaataaaag aggtaaagaa aattacaatc cctacagcta cggaaatatc    300
ttaccaactg ctgtgttgcc cgtgtgggcc catctcacca agcctgatcg acagaagagg    360
gtacatccag cccgacacgc cgcagccagc agcaccctcc aakggcatca ccatgtacgg    420
ggccacgcat cacagatgac atgggtgcag cacgcccctg tgcagagcga gcccagcttc    480
accagcgamg agctgcacct gcccggggaa ncctgggcct ggggcaag                 528

<210> 881
<211> 723
<212> DNA
<213> Homo sapiens

<400> 881
ttttttttcc awgtacwtga aaaatccatt ctcttggtgt cactacmagt ctgcttagtt     60
ttaagtgaaa ttccttttat gtctacttgg tttttacttg tgtcaacatt tagtatgcta    120
cctcttctat wgaaggatga actcctaatg ccctctgttg tgacaacaat ggcatttttt    180
atagcttgtg taacttcctt ttcaatattt gaaaagactt ctgaagaaga actgcagttg    240
aaatcctttt ccatttctgt gaggaaatat cttccatgtt ttacatttct ttccagaatt    300
atacaatatt tgtttcttat ctcagtcatc actatggtgc ttctgacgtt gatgactgtc    360
acactggatc ctcctcagaa actaccggac ttgttttctg tattggtgtg ttttgtatct    420
tgcttgaact tcctgttctt cttggtatac tttaacatta ttattatgtg ggattccaaa    480
agtggaagaa atcagaagaa aatcagctag ctgtattcct aaacaaattg tttcctaaac    540
aaatgtgaaa atgtgaacag tgctgaaagg ttttgtgaac tttttgctat gtataaatga    600
aattaccatt ttgagaacca tggaaccaca ggaaaggaaa tggtgaaaag tcattgttgt    660
ctacacaaaa taaatgtata tggagaccaa araaaaaaaa aaaaaaaaaa aaaaaaaaaa    720
aaa                                                                  723

<210> 882
<211> 1092
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (882)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (927)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1071)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1078)
<223> n equals a,t,g, or c

<400> 882
gggaactggc atttgacacg agctcagctg atgttcgttg ttctgtcttt aagtgtctgc     60
caatgatttt ggacaacaaa ctgagccacc ccatttttag agcagctcct tccagctctc    120
agatacagtc tccacgacaa ttcggagaaa gtgagggtag cttttgtkga catgctgttg    180
aagatcaaag ctgtgagggc tgctaagttt tggaaaatat gtcccatgga gcacattctg    240
gttcgtctgg aaactgattc tcgacctgtg tctcggcgcc tggtgagcct catctttaat    300
tctttcctgc ctgtgaatca gccggaggag gtctggtgcg agcgctgtgt caccctggtg    360
cagatgaacc acgccgctgc caggaggttc tatcagtacg cccacgaaca caccgcctgc    420
accaacatag caaagctgat tcacgttatt cgtcattgct taaatgcctg tatccagagg    480
gcagtgagag agcctccaga ggacgaggag gaagaggacg gaagggagaa ggagaatgtg    540
actgttctgg acaaaacact gtcagtaaac gatgttgcat gcatggcagg tttactagaa    600
atcattgtga ttctctggaa aagtattgac agaagtatgg aaaataataa agaggccaaa    660
ctttacacga ttaacaagtt tgcctctgtg cttccagagt atctgaaagt atttaaggat    720
gatcgctgca agatcccttt attcatgcta atgtccttta tgccggcctc tgctgtcccc    780
ccattcagct gtggtgtgat ttccacgctg agaagccggg aggagggcgc tgtggacaag    840
agctactgca ctttgktgga ttgcctctgc tyctgggggc angtggggca cattctggag    900
cttgktgaca actggcttgc cacagancat gcccargcca agarcaacac agcttctaag    960
kaaggtgcag atccatgaca cacgcccagt caaacctgaa ttggcattgg tctacattga   1020
gtatctgctg actcatccaa agaaccggag kgttgttttt gtcttgagaa nttacctntt   1080
tgaaccctga ac                                                       1092

<210> 883
<211> 2991
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (50)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (88)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (110)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (254)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (258)
<223> n equals a,t,g, or c

<400> 883
accttaaggt ngcccaaaag gctttttggc caggcccttc taggaagggn attcctttcc     60
ttaatatccc cagtccccaa cttaggcntt atggatccag gatttccaan cttaattggc    120
actaggtatc ctaaatactc aggggaatcc tttttggctc cactatattt actttaacag    180
gatttccctt tcccacwtac atacaccwtc atggctarga amccmccaag tttttcttct    240
atcccccact aaanttanca ggtttcacca acttgaawtt ataggggact atggggaaaa    300
ccrgagaagt atatggaaga aggaagaagt gtgaataggt cctacagaat tttacaatca    360
ctttgccaag acaactataa atactatgaa taattacttg aaatcaggtt gtgtagaatc    420
tatagttctc ttaaaaacaa gttttgattc tcaatattgc atttttatac caaataaaag    480
gatttagatc taacgtattt tagtagcata cttactacct gcagactaaa ttcatttctc    540
aagtactcta aaaaacttca aatagaacaa actttatgag atgctataac ttatcacaaa    600
agaaatatta gcatttataa aattaagata ataaaatgta aaagctaaaa accaaaattt    660
gccattcata tttaaatata acatagaaaa agttatgtgg ataatatgaa aataaaattg    720
tttaggtgaa caattcactt gaagacactc actgtttctc cttctgagta actaaccatt    780
atagcttttt attgatgaaa catcattatc tcacatctga aattctttgg ctggaatgtt    840
ttagtaacat aagacactcc tgtatataac aactctgaca gaacagagga gttgcaaaat    900
aaaaaaagta ggagtcatat tttaaagcat ttgataaatt tttaaataaa ttttttaaaa    960
tgtaaagcca atctatcacc aaaaatggca taaatgtaaa cacaagctaa ttttataatc   1020
cactgctatt ttaaataaaa taatttgggg ttcattattt tgccttttta gttttgtatt   1080
tagcatagaa gtaccttcta ttgccactaa agacatcaca ttagttttaa aaatggaaaa   1140
gaaaaaacaa aatgcaacaa aacttatgag tttaatttgt gaattttaga actaagaatt   1200
acaattttct gttactattg taaaatggga ttatctgacc acatagttaa cattttaatt   1260
acatcaaaaa aaatttaaat tttttttttg tatttttaaa aataaagcaa atttatgtac   1320
ttgtaaatac tttttaaaga ccaacaaatg cacttcttaa tctactgcct ttatacaaag   1380
attaaaagga aaaaaaagct ttatggctcc agcacccaag attgagaaca aaaaatacct   1440
caaataaata tttataactt gcaaaaaaaa gctaaagatg tttgaaagat taaatgaaga   1500
aacattctga aactagaacc catttcttta gcttttctct cccagacttt ccattctata   1560
tactacagtt gtagagatgt cctcatttga ctcaggtgac acttttttcc atactgtctc   1620
ttttaaagca agttcttgtt ggagactttc atagtccaat ggtccaaagg aatgcctttg   1680
atcaccacct tctcttcgag gatcaagttt ttttgcaaag tgtctcaaat tatcatagtt   1740
atggaaatta cacagagaaa caagatcgtg acaaaagtga attcccttaa cactgttgcc   1800
catcttatcc agaggaggag accagcacat catacccata acattgggga caactaaaag   1860
aatgccccca gcaactccag attttgcagg aagaccaaca tggaaagcaa actgccctga   1920
gaagtcatac atgccacagg aatgcatcaa actcaatgta tttcgaactg cttcagggct   1980
cagtactctt tcaccagtaa ttgggcagaa accaccatta gccagtgtcg cagccatcac   2040
actggctgat tcacaagtca cttcaatgga gcacagctgg aagtagaagt ctaatatacc   2100
aaccatgtct gtgccttctg gaaaacactt cttttctttt aagtaatatc ctattgcaaa   2160
atttcgatct ccactttctc tttcagactg aaacgttgca ttactgaatc caacatattc   2220
attaccagcc atcttattca aaaactgcat gacatagtca aatttttcag cattatttac   2280
tccttgcttt attagtgaag tcacaacaat tgctccagca tttaccatag gattatgtgg   2340
tttatcatct tcattcaaaa atagtttgtt gaatcttagt ccactcggct cttttccaac   2400
atatcgatgc acatattcag ttccaagatc attaacagca atggcatatt tcaaaggttt   2460
tacacaggac tgaagacaga agggaacttt ggtatctcca gtagaatgcc tctgtccatc   2520
tactgtacaa acagacacac cccacaaatc gggactgaat ttggccagtt gaggaatata   2580
atctgcaacc tttcctccag actgcttttt agcactttca tataactcat caatgtgtga   2640
ggtaaaagac ataaagtcag gaatcacaaa ctttcttcta aatgcttgtg tcaacaaaac   2700
aatgttgctc tgaacacatt ttttaaaaag atctttgtct agcatgacac catctgatgt   2760
tgtttgaaga gttaatctta acatatccat acactctttc aacctgggat cagacgttcg   2820
caatcctgta gatttgagtg ctgtaataaa tttatgaaca ggtattttct cttgtccttc   2880
agcaattgta tagaacagca aatcttccaa gctaggtaac agaccctgtt ttattttatt   2940
ttcacctgag gccaccagct ctttgccctc gctgttgcca aacgcgtccg c            2991

<210> 884
<211> 2155
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2125)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2152)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2154)
<223> n equals a,t,g, or c

<400> 884
ggcacgagcc ttccggcgcg gggagggcgc tgaagatcgg ggccgctcgg ccgcaccgcc     60
tccagcgccg cgggatgtag cgcgggggac cgcggccccc agcagagccc gcctgcccgg    120
cttgtctacc atcagaggga gatctctgcc ccctggggct gagagacccc aacctttccc    180
caagctgaag ctgcagggta ttgaggtacc agccagatgt cttcccacaa aggatctgtg    240
gtggcacagg ggaatggggc tcctgccagt aacagggaag ctgacacggt ggaactggct    300
gaactgggac ccctgctaga agagaagggc aaacgggtaa tcgccaaccc acccaaagct    360
gaagaagagc aaacatgccc agtgccccag gaagaagagg aggaggtgcg ggtactgaca    420
cttcccctgc aagcccacca cgccatggag aagatggaag agtttgtgta caaggtctgg    480
gagggacgtt ggagggtcat cccatatgat gtgctccctg actggctaaa ggacaacgac    540
tatctgctac atggtcatag acctcccatg ccctcctttc gggcttgctt caagagcatc    600
ttccgcattc atacagaaac tggcaacatc tggacccatc tgcttggttt cgtgctgttt    660
ctctttttgg gaatcttgac catgctcaga ccaaatatgt acttcatggc ccctctacag    720
gagaaggtgg tttttgggat gttctttttg ggtgcagtgc tctgcctcag cttctcctgg    780
ctctttcaca ccgtctattg tcattcagag aaagtctctc ggactttttc caaactggac    840
tattcaggga ttgctcttct aattatgggg agctttgtcc cctggctcta ttattccttc    900
tactgctccc cacagccacg gctcatctac ctctccatcg tctgtgtcct gggcatttct    960
gccatcattg tggcgcagtg ggaccggttt gccactccta agcaccggca gacaagagca   1020
ggcgtgttcc tgggacttgg cttgagtggc gtcgtgccca ccatgcactt tactatcgct   1080
gagggctttg tcaaggccac cacagtgggc cagatgggct ggttcttcct catggctgtg   1140
atgtacatca ctggagctgg cctttatgct gctcgaattc ctgagcgctt ctttcctgga   1200
aaatttgaca tatggttcca gtctcatcag attttccatg tcctggtggt ggcagcagcc   1260
tttgtccact tctatggagt ctccaacctt caggaattcc gttacggcct agaaggcggc   1320
tgtactgatg acacccttct ctgagccttc ccacctgcgg ggtggaggag gaacttccca   1380
agtgctttta aaaataactt ctttgctgaa gtgagaggaa gagtctgagt tgtctgtttc   1440
tagaagaaac ctcttagaga attcagtacc aaccaagctt cagcccactt tcacacccac   1500
tgggcaataa actttccatt tccattctcc tagctgggga tggggcatgg tcaaacttag   1560
ccatcccctc ctcagcaagg catctaccgg cccctcacag agacagtact ttgaaactca   1620
tgttgagatt ttaccctctc ctccaaccat tttgggaaaa ttatggactg ggactcttca   1680
gaaattctgt cttttcttct ggaagaaaat gtccctccct tacccccatc cttaactttg   1740
tatcctggct tataacaggc catccatttt tgtagcacac ttttcaaaaa caattatata   1800
ccctggtccc atctttctag ggcctggatc tgcttataga gcaggaagaa taaagccacc   1860
aacttttacc tagcccggct aatcatggaa gtgtgtccag gcttcaagta acttgagttt   1920
taattttttt tttttcttgg cagagtaatg taaaatttaa atggggaaag atatttaata   1980
tttaatacta agctttaaaa agaaacctgc tatcattgct atgtatcttg atgcaaagac   2040
tatgatgtta ataaaagaaa gtacagaaga sacttggcat tcaaaraaaa aaaaaaaaaa   2100
aaaaaaaaaa aaaaaaaaaa aaaanaaaga aaaaaaaaaa aaaaagggga anana        2155

<210> 885
<211> 821
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (56)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (725)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (775)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (797)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (798)
<223> n equals a,t,g, or c

<400> 885
naagatgtnn ttaaccctca ctaaagggaa caaaagctgg agctccaccg cggtgncggc     60
cgctctagaa ctagtggatc ccccgggctg caggaattcg gcaccacttt gtatgtatag    120
tagccttttg ccctcatcac aacttagtgt gaggtatgtg ttcctgtcct aattctacag    180
agaaggaaat tggaattcag tgagttcatg ttcttacagc tagtgactgg tcgatccasa    240
attagagcac mggtccgtct gactccaaaa cctatatgtg cttttcacta taccacaata    300
acaacgaata tttgttctgt acaattcaca actctttggt ctaccttatt attattatta    360
ttattactac cactacttac atcttcacta gtcagtargt acagccwaga ttatcacgac    420
ccccatttca ctggtaggga aactgagact cggaagcttg cccaagatca cacagctggt    480
aagtggagga gaaccaggac ttcagacaga cttcctgact ccagatcttt tttttctttc    540
catgacatca cattgctgcc ttaattcatt tgcacaatgc atgattgtat ggccagtgtt    600
cactgacacc tttcctacag aagtatcaat gagcccaggc attacgtaga gccatgtgga    660
gaagaaaata attcatacct ttcagaggag cttccatttt agtgggggtt gatacaaagc    720
acccngaaag taaatgcctt gagaatagtt cacaagttaa gaatttaaaa tatanggccg    780
ttgtttccat aatgaanncc cataaatttg ggccataaaa c                        821

<210> 886
<211> 882
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (867)
<223> n equals a,t,g, or c

<400> 886
gcttccttgt aggaaatgac cttcactctg ggtttaactg gagtggcatc acctcccagg     60
gagacagtta cttcctggag gargtggtgt ttcctccacc cataggtgcc ctgccccatc    120
ctcatggtgg cagcaaatca gcatgtgctg gggagaccct ggggtagcag ccactgacct    180
cacacctgga ggaagctgtg tgaccgattc atgagcttat gcctgaagac agagcaagca    240
ctccccgcac cacgacgatg acgttcactt gtwttgwgtt tttcgatctc ttcaacgcct    300
tgacctgccg ctctcagacc aagctgatat ttgagatcgg ctttctcagg aaccacatgt    360
tcctctactc cgtcctgggg tccatcctgg ggcagctggc ggtcatttac atccccccgc    420
tgcagagggt cttccagacg gagaacctgg gagcgcttga tttgctgttt ttaactggat    480
tggcctcatc cgtcttcatt ttgtcagagc tcctcaaact atgtgaaaaa tactgttgca    540
gccccaagag agtccagatg caccctgaag atgtgtagtg gaccgcactc cgcggcacct    600
tccctaatca tctcgatctg gttgtgactg tggcccctgc cgtgtctcct cgtcagggga    660
gacttttagg aggccgcagc cttccatcac cggatcagtt tttcctctta ggaaagctgc    720
aggaacctcg tgggctccag ggacccaggc ccacatccat ccagcgttcc cgctggctgt    780
gggacagaca gggaggggcc tgtacagaaa caccacactg tttattaaat cacaatgatt    840
tttattaaaa aaaaaaaaaa aaaaaanaaa aagggcggcc gc                       882

<210> 887
<211> 1101
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (930)
<223> n equals a,t,g, or c

<400> 887
tcgacccacg cgtccgccca cgcgtccgca accccctctt taaaatgcaa aatggccctt     60
ccctaaaata acacacaacc acaaccgcag ctggctctgc acgaaggcca tgctgcagct    120
cttttcttcg gaagtcgatt ttcctccgtg gaatttggct gggcttgtgg tagcgtttga    180
gactctgcaa gagcacgtcc acgccaacca gtctctggtc accgactggc tcgcaaattc    240
cccatttaag gaaaccagca ggcctctgtt atgaaactcg gggaaggaat gtgaattatg    300
ctccatgcgg aggctcctgc tcctgcacgt tttccagcct tttccatggg ccacggtgga    360
gcatttgggg aaggcctgtg tggattcccc cccaagtcca gactgatgcc cctgatacct    420
tctcaggagg tggcggaggg tctgggctct gtccaggctc ctaggggtgg ggacgtgcag    480
gtaaagcaag gcgtctgccg cagacgcggg agccttccct gggctggctg ccagcacctt    540
ggagtcccag gctgccagga aaagttcacc cacacccggg ctttgctggc gaagggtgag    600
tcatatgatg gccgggctcg ggccctcagc agacaccaag tgtgttccca gagcagccgc    660
tcagcgcctg taacctggaa caggccagcy tttcggggsc tcagttttct catctgccta    720
atgggaatag caattcccac cttccctgtg ttggttgggt tctcactaga tgcacaggag    780
acagcagctt kagagggact gtttggarar ctgttccatg tgacacccct cttaccctgt    840
ccccacgggg ccggaggagc aggggcttgg tgatagcagc tgggcgcagt cagcctctgc    900
agggaagagg gcatgtttgg ttcgaggctn ytatgccctc attcttgttg atcttgtcac    960
agcccctctg gaaggtggag atggtactcg ctcaggaacg ataccactca aggaagcatg   1020
gccccctgga tggggtggcc cttggtgcac ctgaggctcc tgaggctgca gagcaccatg   1080
gtgggggagg aggcggctgt g                                             1101

<210> 888
<211> 1313
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1249)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1268)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1283)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1291)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1295)
<223> n equals a,t,g, or c

<400> 888
caacacccca tctctctctc tctaaaaaaa gagaactggc cgtgagctat tgtgcccagc     60
tgggatcttg acaaagacac tatttctctc ctttcacctg tgctgtgtat ttttccctcg    120
cctagttccc agacctcact gctatatgtc ttctccctgg caggcaggat gacgcaaaac    180
acggtgattg tgaatggagt tgctatggcc tctaggccat cccagcccac ccacgtcaac    240
gtccacatcc accaggagtc agctttgaca caactgctga aagctggagg ttctctgaag    300
aagtttcttt ttcaccctgg ggacactgtg ccttccacag ccaggattgg ttatgagcag    360
ctggctctag gggtgactca gatattgctg ggggttgtga gttgtgttct tggagtgtgt    420
ctcagcttgg ggccctggac tgtgctgmgt gcctcaggct gtgccttctg ggcggggtct    480
gtggtgatcg cagcaggagc tggggccatt gtccatgaga agcacccggg caaacttgct    540
ggctatatat ccagcctgct caccctgrca ggctttgcta cagctatggc tgctgttgtc    600
ctctgcgtga atagcttcat ctggcaaact gaaccctttt tatacatcga cactgtgtgt    660
gatcgctcag accctgtctt ccctaccact gggtacagat ggatgcggcg aagtcaagag    720
aaccaatggc agaaggagga gtgtagagct tacatgcaga tgctgaggaa gttgttcaca    780
gcaatccgtg ccctgttcct ggctgtctgt gtcttgaagg tcattgtgtc cttggtttcc    840
ttgggagtag gtcttcgaaa cttgtgtggc cagagctccc agcccctgaa tgaggaagga    900
tcagagaaga ggctactggg ggagaattca gtgccccctt cgccctctag ggagcagacc    960
tccactgcca ttgtcctgtg agcygccaaa gaccccacgg ggtgcccgca tgtccctgtc   1020
tagggcagcc cagggccccc actcctggct cctcacactt gcctccccta tggccgctct   1080
ccagaccctc ctcctttctt ctccccacat ccgcacctgc tgttcccact ctggggttct   1140
caagtccatg aacagatatt gttgcatttt ccacaatgct gattaaacat aataaacaat   1200
ccagaaaagc araaaaaaaa aaaaaaargg cggccgctct aaaaggatnc ctcgaagggg   1260
cccaagcntt aagcgttgca tgngaagtca naagnctttt ccctaatagt gaa          1313

<210> 889
<211> 557
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (549)
<223> n equals a,t,g, or c

<400> 889
ttcggcacga aggagactgt aaacaaagat atttgtgaaa agggaacaat tcagcaaatg     60
ataggaatct ttaaaaatat aataagcaag cctaatgaaa aggaagaagc cattgttttg    120
gaaatccagt ctgatatatt acttatccta tctggcsttt gtgagaatca cattcaaagg    180
aaggaaattt tcggaactga aggagtagat atygttcttc atgtgatgaa aacagacccc    240
aggaagttac agagtggctt aggctataat gtacttcttt ttagtacatt ggacagcatt    300
tggtgctgta ttttgggatg ttatccctca gaggattatt ttcttgaaaa ggaaggcatt    360
tttctccttt tggatttgtt agcattgaac caaaaaaatt ctgtaatcta atacttggga    420
ataatggttg aattttgtga ataatcccaa aactgcagct catgtcaatg cttggcaagg    480
gaagaaggat cagacagctg ctagtctttt aatttaaatt gtggaggaaa ggaggaaaaa    540
gaactaggng taaaacg                                                   557

<210> 890
<211> 1765
<212> DNA
<213> Homo sapiens

<400> 890
gagaaaacaa ttctgaccgg agaatgctgt tacctgaacc ccttacttcg aaggatcata     60
agattcacag gggtgtttgc atttggactt tttgctactg acatttttgt aaacgccgga    120
caagtggtca ctgggcactt aacgccatac ttcctgactg tgtgcaagcc aaactacacc    180
agtgcagact gcyaagcgca ccaccagttt ataaacaatg ggaacatttg tactggggac    240
cgggaagtra tagaaaaggc tcggagatcc tttccctcca aacacgstgc tctgagcatt    300
tactccgcct tatatgccac gatgtatatt acaagcacaa tcaagacgar gagcagtcga    360
ctggccaagc cggtgctgtg cctcggaact ctytgcacag ccttcctgac aggcctcaac    420
cgggtctctg agtatcggaa ccactgctcg gacgtgattg ctggtttcat cctgggcact    480
gcagtggccc tgtttctggg aatgtgtgtg gttcataact ttaaaggaac gcaaggatct    540
ccttccaaac ccaagcctga ggatccccgt ggagtacccc taatggcttt cccaaggata    600
gaaagccctc tggaaacctt aagtgcacag aatcactctg cgtccatgac cgaagttacc    660
tgagacgact gatgtgtcac aagctgtttt ttaaaatcat cttccaattc tatacttcaa    720
aacacacagt tgctcaatgt caaactgtga tgacaaatat tacgtttatc tagttagaag    780
ctaatgtttt gtacattttt tgtatgagga agtgatgtag cttgccctga tttttttttt    840
tttttttttg gtcagcttta atatatttat gccagaattt taaaaccaac aaaattttct    900
tgttcaagcg tgcattgaag aaccacattt attcaatggt tgaygttgtt ttgtgatatt    960
tgtacacaaa ttttcttttc tcagttttat aaacacagaa tataacaatt cactttaaac   1020
ttttattacc acagttgctg cctcctccag aatttttgaa ttttaataaa aggcaaactt   1080
ttgagctgca ggaaggacaa tgttggttaa taataaatct caaagtcaat tgtagaaaaa   1140
aaattgtctt caaaaagaat gttgcactct gatctcttaa caaattgtta cgttcaaagt   1200
ttaaagtgat atattaacar agtcacctag ttatacaaac aattgtcaga gaattctgga   1260
tttggagggt attggggtta tatgattctt tcttagataa tggcctctac taaataactc   1320
aagatctttc tggaatgtct tctggcaggc aggtgccact gtcagctttt ctccaaaaag   1380
cagccaacat cagcctcccc tgtcaactca acagttttgt atctcatatt atatggactt   1440
tatatgaaaa tgaatatttt acagtttgca cagtattatt ttacagaaaa ggaatcagag   1500
aatctacaac atagggcccc agaacaacag tttcactttg tggcttttaa ttattctaga   1560
attttaactg catctcattt ttctagcatg gtgagaacta atatgtaact cctttgattg   1620
aaggagctct tttgtccgta cctatcagaa tgttttcttg acacttccat gttggctctt   1680
ctcagctttt tttgtacata tttttttttt ctaaagagaa gaaaaagtta tcacaaaatg   1740
taaaaaaaaa aaaaaaaaaa aaaaa                                         1765

<210> 891
<211> 1167
<212> DNA
<213> Homo sapiens

<400> 891
ctatgtaact gcaagatgct gctcgccaac acagcaacac caggcatttc aattaaataa     60
ttttattggg ggaaaaaaac cactttgagc accaaagcaa gaaaagtgta ttattcaatc    120
agtttcccag atcacatgcc aagaacacaa tgctcactgt ggtgcctggc agacggtcca    180
caaccagcgg gtgcgttcag cttgaatgga ccggggtccc acagtgtttg tgccacaagt    240
caatggcctt gctcacgatc gcgtctgagc tgtcctgggg aatattttcc agaaactttg    300
ttatcttctc tgcactgttc agtgccataa cttttatttt aaaggttaat aaaatttcga    360
cagctacaaa aactaggatc ttacaggatc cactcacaac tttatcccaa accctctgta    420
aactggattc aggcaaacat cccgcaaagc acctcttgaa ccagagatca taaggaagtt    480
tgggcgccgc ggaacacatc ctcagatgag tcagcagtct gccatcttcc agattcaagt    540
attgttcaaa cgcttttggc aactggggca aggaatcccg gtacttggta tttaattggt    600
tcacaaagcg tcgggtgatc cagtaacagt cgacactatc ttccaccatt tcctccatgg    660
ctttagctat ggcaagaaac acttcatcat ctggctccag tggaaaagag ggacttcgag    720
gtaacttccc agactccagc tgatacatgc ggagatagac ttcagcctga ggtgtggcat    780
cactaacaaa gcgaacgact ttcagggcat gaaggacatc caagtactgc tccttacgat    840
acatcatcac cttggcatgg gactcgtggt gtggaggcaa gattcctaga agcaccttcc    900
ataccaatgc acggtacatg gacgggagag ggaacctctg actaaaagta caaagtttct    960
cagtatccag acggtcatct tttaggagaa tttctaatga tttcttttct tcaactccac   1020
gaaaccccac tttctcataa tatactgaac gaaagtttct ctgagagtcc tcagtcatat   1080
ttcattctgg gacacccgcg cgcgcccaga cggcccggga gacaaaactc agcgccgctg   1140
acgctgacgc tgccgctgtc gctgccg                                       1167

<210> 892
<211> 1225
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (59)
<223> n equals a,t,g, or c

<400> 892
gtgcactcta acgatctctt tgccatcttg ttttaatctg acagttctca gacatagana     60
aaaaaggtaa ctcatgcatg tactaccttt tttctctatg tctgagaact gtcagattaa    120
aacaagatgg caaagagatc gttagagtgc acaacaaaat cactatccca ttagacacat    180
catcaaaagc ttatttttat tcttgcactg gaaggaatcg taagtcaact gtttcttgac    240
catggcagtg ttctggctcc aaatggtagt gattccaaat aatggttctg ttaacacttt    300
ggcagaaaat gccagctcag atattttgag atactaagga ttatctttgg acatgtactg    360
cagcttcttg tctctgtttt ggattactgg aatacccatg ggccctctca agagtgctgg    420
acttctagga cattaagatg attgtcagta cattaaactt ttcaatccca ttatgcaatc    480
ttgtttgtaa atgtaaactt ctaaaaatat ggttaataac attcaacctg tttattacaa    540
cttaaaagga acttcagtga atttgttttt attttttaac aagatttgtg aactgaatat    600
catgaaccat gttttgatac ccctttttca cgttgtgcca acggaatagg gtgtttgata    660
tttcttcata tgttaaggag atgcttcaaa atgtcaattg ctttaaactt aaattacctc    720
tcaagagacc aaggtacatt tacctcattg tgtatataat gtttaatatt tgtcagagca    780
ttctccaggt ttgcagtttt atttctataa agtatgggta ttatgttgct cagttactca    840
aatggtactg tattgtttat atttgtaccc caaataacat cgtctgtact ttctgttttc    900
tgtattgtat ttgtgcagga ttctttaggc tttatcagtg taatctctgc cttttaagat    960
atgtacagaa aatgtccata taaatttcca ttgaagtcga atgatactga gaagcctgta   1020
aagaggagaa aaaaacataa gctgtgtttc cccataagtt tttttaaatt gtatattgta   1080
tttgtagtaa tattccaaaa gaatgtaaat aggaaataga agagtgatgc ttatgttaag   1140
tcctaacact acagtagaag aatggaagca gtgcaaataa attacatttt tcccaaaaaa   1200
aaaaaaaaaa aaaaaaaggg cggcc                                         1225

<210> 893
<211> 1493
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1488)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1492)
<223> n equals a,t,g, or c

<400> 893
atctctgnct cgtatccgcc ttgcctccac aagtgctggg attacaggtg tgagccacca     60
cacccggcct atattgtttt gaaagcatac tctatatata gttaygggca gaggcacagg    120
catcctcagc agctgattca ggagatgatg gtaaagctag ctaactatga attaaacatt    180
cacatatcca gtctacctgg tccagtaata atacaagcaa atcttgtatt tcaggaacaa    240
atcaaggttc tcttaatttt ttggcttata tacaatgaag taaaaacttg ataaacatgg    300
tttcaaattg aggaggagag tcttggatgt atgttttaat atgtatacct tataattctg    360
cctctagcca aatgctatgt ttgcaaaatg tggcatctgt tagtttttat tgtctgtgtc    420
ttctttgttt actatacctt gggtaatttt gtgttaccaa aaaaaaaaaa aaaaaggaag    480
tgtaatgtca gacacacaag aaaagcaaat cagtgttgta agcttaaagt acaatttcaa    540
aggtcattac caacagcagg gtttttttta tactttaaaa acattatgct acatatcatt    600
gccattttca tattttgggg ttttgctact cttatacaat ggaatcaatg gaaatgtcat    660
ccagccactg aattgccatt attatatcta aaaagtttct aagatgacag ttatcactat    720
tttgttttat ctccatgctg acatttgaaa gaaggtacta gtatccctct agccagattg    780
cttagttttt cgttggtaat caaacaacag ttgtactaaa ggaaagtaaa gctaggacct    840
aaatcagaat catagttgcc tgcatatatg gtaacaaggt cgtgtgcatt tgctttcaca    900
gtgatgagtg agaggatgag aagaaattat ttgacatttt tctgtggttg aatagaagac    960
acctttcttt tgtctttagg tttaggagga gatactaaga tactggatgt ttatcctatc   1020
ttagtttggt tggagtaata agagagaaga agagggtgga ctttggcttt tcagtgtttt   1080
ttcccctaaa gagtgatatt gctgacgttt ctatcaattt tacacataat atgtggctat   1140
gaaaccatat atctcactta agtaacaaag taatcacttt gtctatcact aagtaataga   1200
caaaaatcat tgtctattat ttaaagccaa caaaacagtg taacagtttt aagttcaata   1260
atgttaagta ttgtatagaa atatattgga ggcaaagttc agttgatgac aattgtgtat   1320
atgttactga tgctgtaaat tatttttaat aaagaaaatt gtattatcaa aaaaaaaaaa   1380
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1440
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaagg ggggcccntt tna          1493

<210> 894
<211> 2791
<212> DNA
<213> Homo sapiens

<400> 894
gtcacctgac acctcaccgg tccggaattc ccgggtcgac ccacgcgtcc gcccacgcgt     60
ccgtaatccg tggttttctg gagcatttca cagcctagga acatacaagg ggggcatctc    120
cctggaatgt aaattgacta agaggaattc aataatggtc aaatgaatgc agaattttag    180
agtcttgctt agtattctca ccacatttcg tttartctac tcatactctt tttctcttac    240
tgctgacact agatggaaaa actcttaatt aaaagtattt cacaaaatgt gctcgttttc    300
agtcattccg tttccactcc agcctgttgt gttgtttttt tgaaataata atttaaagta    360
attttccttt tgcaggatgg catagtcaat ccaacaataa gaaaagattt gaaaactgga    420
ccgaaattct actgctgtcc aattgaaggc tgccccagag gccctgagag accgttttct    480
cagttttctc tcgtaaaaca gcactttatg aaaatgcatg ctgagaagaa gcacaaatgt    540
agtaagtgca gcaattcgta cggtacagaa tgggacctga aaagacatgc agaggactgt    600
ggcaagacct tccggtgcac atgcggctgt ccctacgcca gtagaacagc actgcagtct    660
cacatctacc gaactgggca cgagatacct gcagaacaca gggacccacc tagtaagaaa    720
aggaaaatgg aaaactgtgc acaaaaccag aagttatcca acaagaccat tgaatcattg    780
aacaaccaac caatccctag accagacact caagaactag aagcttcaga aataaagcta    840
gaaccatctt ttgaagactc ttgtggctct aacactgaca agcagactct tacaacacca    900
ccgagatatc ctcagaagtt gcttttacca aagcccaaag tggctttggt taaactaccc    960
gtgatgcagt tttctgtcat gcctgtcttt gtgcctacag ccgactcctc agcccagcct   1020
gtggtgttag gtgttgatca gggctctgcc acaggggctg tgcacttaat gcccttgtca   1080
gtaggaaccc tgatcctcgg cctagattca gaggcttgct ctcttaagga gagcctacct   1140
cttttcaaaa ttgctaatcc tattgctggt gagccaataa gtactggtgt tcaagtgaac   1200
tttggtaaaa gtccatctaa tcctttacaa gaactaggga acacgtgtca aaagawtagc   1260
atttcttcaa tcaacgtgca gacagatctg tcttatgcct cacaaaactt tataccttct   1320
gcacagtggg ccactgctga ttcctctgtg tcgtcttgtt ctcaaactga tttgtcgttt   1380
gattctcaag tgtctcttcc cattagtgtt cacactcaga catttttgcc cagctctaag   1440
gtaacttcat ctatagctgc tcagactgat gcatttatgg acacctgttt ccagtcaggt   1500
ggggtctcca gagaaactca aaccagtggg atagaaagtc caacggatga ccatgtacag   1560
atggaccaag ctggaatgtg cggagacatt tttgagagtg ttcattcatc atataatgtt   1620
gctacaggta acattataag caacagttta gtagcagaga cagtaactca tagtttgtta   1680
cctcagaatg agcctaagac tttaaatcaa gatattgaga aatctgcacc aattataaat   1740
ttcagtgcac agaatagtat gcttccttca cagaacatga cagataatca gacccaaacc   1800
atagatttat taagtgattt ggaaaacatc ttgtcaagta atctgcctgc ccagacattg   1860
gatcatcgta gtcttttgtc tgacacaaat cctggacctg acacccagct cccatctggc   1920
ccagcccaga accccggaat cgattttgat atcgaagagt tcttttcggc ctcaaatatc   1980
cagactcaaa ctgaagagag tgaacttagc accatgacca ccgagccagt cttggagtca   2040
ctggacatag agactcaaac ggacttctta ctcgcagata cctctgctca gtcctatggg   2100
tgtaggggaa attctaactt cttaggcctt gagatgtttg acacacagac acagacagac   2160
ttaaactttt tcttagacag tagccctcat ctgcctctgg gaagtattct gaaacactcc   2220
agcttttccg tgagtactga ttcatctgac acagagaccc aaactgaagg agtctccact   2280
gctaaaaata tacctgctct agaaagcaaa gttcagttga acagtacaga aacacagacc   2340
atgagttctg ggtttgaaac cctggggagc ttgttcttca ccagcaacga aactcagaca   2400
gcaatggatg actttcttct ggctgatctg gcctggaaca cgatggagtc tcagttcagc   2460
tctgtagaaa cccagacttc tgcggaacca cacacagtct ccaacttcta aaactaacgg   2520
tggagtccat gtgtgaaatg gcatctacca tttcctctgg attaaaacta cggactgggg   2580
acaacagtat taattcgatt gaatgtggct gatgatgcag ttgcttagct tctttgtgtt   2640
tctttgcctt ttgtacttgt aaacagaaat ttgcgtataa atgtgagtgt attataaagt   2700
ttgagatgtt gatctaaatt gtttttgtgt tgcctacatt tgccttttca cagctagtct   2760
tttcatgtta aaaaaaaaaa aaaaaaaaaa a                                  2791

<210> 895
<211> 1595
<212> DNA
<213> Homo sapiens

<400> 895
tattcgccaa gctcgaaacc aacctcacta aagggaacaa aagctggagc tccaccgcgg     60
tggcggccgc tctagaacta gtggatcccc cgggctgcag gaattcggca cgaggataaa    120
tgtaatgtat tgtgatcaga tcaaggtagt tagcatattc acctcaaacg tgtatcattt    180
ctttgtgttg ggagcattta atatcctagc tatttgaaac tatatattat tgtcagctat    240
agtcatccta cagtgctata gaacactaga acttattcct cccatatagc tgtaattttg    300
tatcttctaa caaatctctc catattcccc cccctcacct ccgctgaaac catttctgca    360
ccacaggtgc yttgaatccc cggccacact gagcacttca tagargaagg tgggcacgcc    420
ggcataggaa acagccttac ctatcctttg cccagagata gttctagttt tgtccttgtt    480
ggggcaggtg ttagggatga agtgagattg ccatcaagaa ggtagatcat gagcctkccc    540
acctcccact gttcttaccc tttccttggt gtctgtkcag cagagccagc tgctttacta    600
acattcttty tccccaaaga tgaaatktgg caactktggk gagatttcgg acaagtsgca    660
gtacatccgg ctgatggtaa ctgttccccs cccaaccccc aacataaaca ctcacaaaca    720
cacatacact tctgggcagg gatttgggga aactggcctt catctctcca gttctttgct    780
ccctgctttt tgtggtttgg gagggtaggt gtcagtgtga tcagcactgg attcaatagg    840
catctttgag gtatgaggca gagttcaaaa tcaaggggaa gccctttttt yattttcctc    900
aggaagcctt cccaggagtc ttgtcctagt aagttaccct ttctgggtct tggtctcttt    960
aagtggacaa taaatggtgg gctcgatctc ctcaggactg tacatctaat tcatatgtga   1020
ctgaaagttc tgtttgcttt ttgccaggac agtgtggcac tgaagggggg ccgtggcagt   1080
gcttccatgg tccagaagtg caagctgtgt gcaagagaaa attccatcga gattttaagc   1140
agcaccatca agccttacaa tgctgaagac aatgagaact tcaagacaat agtggagttt   1200
gagtgccggg gccttgaacc agttgatttc cagccgcagg ctgggtttgc tgctgaaggt   1260
gtggagtcag ggacagcctt cagtgacatt aatctgcagg agaaggactg gactgactat   1320
gatgaaaagg cccaggagtc tgtgggaatc tatgaggtca cccaccagtt tgtgaagtgc   1380
tgatccctct tccttcccag ttgcccttaa gaactgagaa aggacaaagt actctaagca   1440
gcagagccca cagaggctcg ttcctttgac ccttgtctcc tggtggctat acgaaacctt   1500
cacaatctgc atgctggact ttattacagc ttcccaagcc ccatcaataa agcccctgtt   1560
cacgctgmaa aaaaaaaaaa aaaaaaaaaa aaaaa                              1595

<210> 896
<211> 2790
<212> DNA
<213> Homo sapiens

<400> 896
gccgcgtgag gacgaggcta tttgaaaaca cgctccggga gctagagcct gaggtcggcg     60
gcgcacgctg ttgccccgtg ggcttctgct ccctcgcttg tcttctcggg cttctcgccc    120
cggccgcggc cggktcctca gtagtcgaga atgactaaaa aaagaaaacg ccaacatgat    180
tttcaaaaag taaaattgaa agttggtaaa aagaagccca agttacaaaa tgctactcct    240
acaaacttta aaacaaagac tatacatctg cctgagcaac tcaaagagga tggaacactt    300
ccaacaaaca atagaaaact taacataaag gatttgctgt cacagatgca tcactacaat    360
gctggggtta aacaaagtgc tcttcttgga cttaaagacc ttttgtctca atacccattt    420
ataattgatg cacacctttc aaacatatta agtgaagtga ctgctgtgtt tacagataaa    480
gatgctaatg tacgattakc agcagttcaa cttcttcaat tcctggcccc caaaatacga    540
gctgaacaaa tttctccatt ttttcctttg gccttggcag atggatccag taggttgaga    600
gaaagtgaag gacttcagga acagaaagaa aatccccatg ccactagcaa ctccattttt    660
atcaactgga aggaacatgc caacgaccag caacacatcc aggtttatga aaatgggggt    720
tcacagccaa atgtcagttc acagttcagg ctacggtatc tggttggagg actgagtggt    780
gtggatgaag gcctgtcatc tactgaaaac ctgaaaggat ttattgagat aataattcca    840
ttgctaattg aatgctgggt tgaagctgta cctccacaac tagctactcc tgttgggaat    900
ggtatagaac gagaacctct acaggttatg cagcaagttc ttaatattat ttcccttctg    960
tggaaactct ctaaacaaca ggatgaaacc cataaattgg agtcatggct tcgaaagaac   1020
taccttattg attttaaaca ccattttatg agtcgttttc catatgtctt aaaagaaata   1080
accaagcaca aaaggaaaga gccaaataaa agcatcaagc attgcacagt tctctccaat   1140
aacatagatc atctcttact gaatttaaca ctgtctgata tcatggtctc cctggcaaat   1200
gcgtcaactt tgcagaagga ttgcagttgg atagaaatga taaggaaatt tgtaacagag   1260
acccttgaag atggctctag gctaaatagt aagcaactga acagattgct gggagtatcc   1320
tggaggttaa tgcaaataca gccaaacaga gaggacacag agactcttat taaggcagtt   1380
tatacattat atcagcagag gggccttatc cttccagttc ggactttgtt attgaagttt   1440
ttcagtaaaa tctatcagac agaagaactg agatcttgta gattcagata tcgtagtaaa   1500
gtgttatccc gttggctggc tggcttacca ttgcaacttg ctcatcttgg ctcccgaaat   1560
cctgagctct ctacacagct tatcgatatc attcataccg ctgcagcacg agcaaataaa   1620
gaattactaa aaagtttaca agctactgcc ctccgaattt atgatccaca agaaggtgct   1680
gtggtggttc tccctgcaga ctctcagcag cgtttggttc agcttgtata tttcctaccc   1740
agtctgccgg ctgatttgct ttctcggtta agtcgttgct gtattatggg aagactcagt   1800
tcaagtttgg ctgccatgct tatcgggata ctgcacatga gatcatcatt ttctgggtgg   1860
aagtattcag ctaaagactg gttgatgagt gatgtagact atttcagctt cttattttcc   1920
acacttacag ggttttcgaa agaggagttg acttggcttc agagccttcg aggagttcct   1980
catgtcatcc agacacagct ttcccctgtg cttctctacc ttacagattt ggatcaattt   2040
ttacaccact gggatgtaac agaggcagtt tttcacagtt tattggttat tcctgcccga   2100
agtcagaact ttgacatctt gcaaagtgcc atcagtaagc atttggttgg gttgactgta   2160
attcctgaca gcacggctgg ctgtgttttt ggtgttatct gtaagctcct ggatcatact   2220
tgtgtagtta gtgagactct actgccattt ctggcttctt gttgctacag tcttctttat   2280
tttctgctca ctatagagaa aggggaagca gaacatctaa gaaagaggga caagctgtgg   2340
ggggtctgtg tctccatcct ggctctcttg cctcgagtcc tcaggttgat gctgcagagc   2400
ctgcgggtga acagagttgg gcctgaggag ctgcctgttg tgggccagct gcttcgactg   2460
ctgcttcagc atgcacccct caggactcat atgttgacca atgcgatctt ggtgcagcag   2520
atcatcaaga atatcacgac attgaagagt ggaagtgttc aggaacagtg gctcacagac   2580
ttacattact gcttyaacgt gtatatcact gggcatcccc aagggcccag tgcactggct   2640
acagtgtatt gaagaggcca tagtacctcc tgtttgaagt tgtttattca catctatctt   2700
atttgaagaa aaagactgat gtaatagatc tttgtcatta aagctgaact tttaaagaaa   2760
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa                                    2790

<210> 897
<211> 998
<212> DNA
<213> Homo sapiens

<400> 897
cgttacacat gacaccagtg cctttgtttc attgggctgg gctctctgga aggtgtgctg     60
ctgcctgagc tgctggaaaa gcactgacag gtgtttgcta gaaaagcact cctggagctt    120
gccaccagct tggacttcta gggactttcc tctcagccag gaaggatttt gatattcatc    180
agaaatacct ccagaagatt caaggagctg tagaggtgaa gtaagcctgt gaaggaccag    240
catgggaatc ctatactctg agcccatctg ccaagcagcc tatcagaatg actttggaca    300
agtgtggcgg tgggtgaaag aagacagcag ctatgccaac gttcaagatg gctttaatgg    360
agacacgccc ctgatctgtg cttgcaggcg agggcatgtg agaatcgttt ccttcctttt    420
aagaagaaat gctaatgtca acctcaaaaa ccagaaagag agaacctgct tgcattatgc    480
tgtgaagaaa aaatttacct tcattgatta tctactaatt atcctcttaa tgcctgtyct    540
gcttattggg tatttcctca tggtatcaaa gacaaagcag aatgaggctc ttgtacgaat    600
gctacttgat gctggtgtcg aagttaatgc tacagattgt tatggctgta ccgcattaca    660
ttatgcctgt gaaatgaaaa accagtctct tatccctctg ctcttggaag cccgtgcaga    720
ccccacaata aagaataagc atggtgagag ctcactggat attgcacgga gattaaaatt    780
ttcccagatt gaattaatgc taaggaaagc attgtaatcc ttgtgaccac accgatggag    840
atacagaaaa agttaacgac tggattctat cttcatttta gacttttggt ctgtgggcca    900
tttaacctgg atgccaccat tttatgggga taatgatgct taccatggtt aatgttttgg    960
aagagctttt tatttatagc attgtttact cagtcaag                            998

<210> 898
<211> 946
<212> DNA
<213> Homo sapiens

<400> 898
gcccacgcgt ccgctccatt tctaaatacc agacttcaaa agataaggtt caaaagtgtt     60
ataagaagat attccttttt ttgtcctaga gaacttattt tcctgtgaaa atgcctacca    120
caaagaagac attgatgttc ttatcaagct ttttcaccag ccttgggtcc ttcattgtaa    180
tttgctctat tcttgggaca caagcatgga tcaccagtac aattgctgtt agagactctg    240
cttcaaatgg gagcattttc atcacttacg gactttttcg tggggagagt agtgaagaat    300
tgagtcacgg acttgcagaa ccaaagaaaa agtttgcagc atccttcgtt tttgtgacca    360
tgatactgtt tgtggcgaac acgcagtcca accaactctc cgaagagttg ttccaaatgc    420
tttacccggc aaccaccagt aaaggaacga cccacagtta cggatactcg ttctggctca    480
tactgctcgt cattcttcta aatatagtca ctgtaaccat catcattttc taccagaagg    540
ccagatacca gcggaagcag gagcagagaa agccaatgga atatgctcca agggacggaa    600
ttttattctg aattctcttt catctcattt tggcgttgca tctattgtac atcagccctg    660
agtagtaact ggttagcttc tctggacaat tcagcatggt aacgtgactg tcatctgtga    720
cagcatttgt gtttcatgac actgtgttct tcattgatgc tgtactcctg aaaatttttc    780
ccacaaggtt ggggaaatga atgggaaatg tcgctggtct gtgtggtatt caaagcagta    840
gtatcatgat gagcgtaacg acccttctga cctggtctca cgatctgaaa taataaaagg    900
ctgtgtcatg tttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                   946

<210> 899
<211> 1236
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<400> 899
gattgtttnc gatcatatac ngcgattggg taccgggccc ccctcgagtt tttttttttt     60
tttttttgca acaagtgtag aatttcccct gatcaaaatc tgaatattgg ttaatgcatg    120
ttttctcatt ctccgtgtat gaacccactc ctaacctctc tcattgcctt tttaagctta    180
agagagagaa ataaaagaaa atggatatag accatgtatt tttatttatg aaaagagagg    240
catattctaa tagtcataag gcaatgtgtt taagagctgc acctgaactg gtattctcaa    300
aactgaaaat agttatcaac tctattcaac ttgtaagatg tatctatgtg cttcccaagt    360
cactggttgt cacccaaatg gaccacggtg actccatcat gccttaagga ggcattatat    420
actgtgtgta gtatgcacat gtatttttaa agaaatgaca ttaagagaga aaagaacagc    480
ctttcaaaca tcagttcctc aaataagggg tgacagtgct atatggctcc cttttaatct    540
cctcacctac tcagttatca aatacctcca aaattagaca aataagggcc agagacaaag    600
ctccatggtg aattgcatct ttcagatgtg ctttcaattc actggttttt aatttcccat    660
tcctgattta ctgaggagta aaggtgagaa tcatccaact gatgacaaag taaaacagga    720
aaacaggata aacagctagg gctctgcggt ttggaggctg gctatcagca aggaaagctg    780
tggaggcaac tatagaccag gcaaacatca caatcaccac aaaaagccga accatgaagt    840
ttacaggtcc tggatcagcc aaaagtacca gccggcaaat cagcattgct actgtcaagg    900
gaagtataca gtaacccagc acacagaggc tctgaaaaaa agatatgttc cctccaagaa    960
gttttgagtt gagggtgatg gtaactgcac caaaccagac aatgacaaac acctctgcaa   1020
attggggccc tccatctttt tcactatctg cagagtctct ttgcagcatt aatgcgagtg   1080
tcacacaaag gatcaaaggg ccccacaaat cccaatctct caaaagagta ttacttttcc   1140
ttgggtacaa aacatgcatg aattttttcc caacagcttt tagatcacgc atcaggggcc   1200
tgggcgatgc tgtccccggg tctcctggag actcct                             1236

<210> 900
<211> 1044
<212> DNA
<213> Homo sapiens

<400> 900
caaagcatta ggattatacc gtgtgagcca tcatgcctct gttaaagttt ttaatgtcct     60
gattaatatg tgattcagat tagtaagact aaaatctatg atcatatccc atcattttga    120
agcttttaaa aatagataat aatgatttgt tacatgcagc ttccatctag atgcataacg    180
ttatttctgg aaatgcgggc cacctacaat gtaaagcagg ctaaacaagg cagcttgtga    240
tttcatttta atcagaaaca caccaaatag gcatcatggc agcagatctg gctgctagtg    300
ttttaaatac agatggattg ttaacatctt tattattcat aattgtctgt caatgttctc    360
tggatgatca agaaactctt tgtgcctcac cctaatcact gaagtaatga aaggagatac    420
ccgcagcaag gactgcaact gtaaatgctg caatcacacc tatgttttgc tgaattttca    480
ataacattgt agttttaatt ggttgttttg gttgttcatc atctgtgttg tccaatgaag    540
cttgactatt catagaagaa ctcatacaag ctgtgtttgt ttcctctgca atttccaaat    600
cttctatttg aattgtgtga tccaacatct ccataaaatg gtccctgatt tcttcagctg    660
actcatcgtc aaatttataa tcacacaaca ttacagtgga tccaggaagg ggaacaaaga    720
ctcgataagg gaggacgtgg aactcttttt cagaaycttt tttttctgga atttcattca    780
aaagcagatc ctcaaatagc atttcacaac gatcagcaac tgtgttcaat atatccctct    840
ttactgcctg cacagcatct ttaactttgg gtttactgct gtggatataa gctctgcatt    900
tcacagcacc cttaaggttt acagaaccgc tacatatctg gactgtggct gtggatctgt    960
ggtctgaatt caggagcaac tgcgttagca ctctgacatc aaaagaatga ctagttgctt   1020
gagtatttcc tctagaagat tttt                                          1044

<210> 901
<211> 2726
<212> DNA
<213> Homo sapiens

<400> 901
gaggcgctag aggcgggggc gccgggaggc gcgggcttgc tcctggggtc tcggccttgg     60
ccggctggac ctgaccctag ggcggcttgc gcagctgtcg ggacgtgact gcgttcagcc    120
gcgtcgggcg tgcttcccag acttgcccaa gttcgggtgc cctagctgcc cctttgcagc    180
cgctggccta cccggcccgc gggtgagaag gttgcgacgg gaggtgggtg gaactcgcca    240
gcgccgggac cgcggattgg ctgcctcggc tttctctttt ccccgtgggc tccggcgtga    300
ggcgctgaag cggccggcag ccggcgaccg gccctcaccg tccgccgggt tgcgctctgc    360
ttttgcggtg aggcgttgac cacgcccata tgaattggag ctctccgcca gtaggagttt    420
ccggaaggag tttgaatttt tgtgattttt atgcttgktt ggtcggtgga atatgttggg    480
atttatgttt gcctctgaac aagtgtcttg ctcacatcgt aaatgacttt ctctccgaaa    540
cgctaaatat tctttcccgc aggagctcat atccttattt tccatgacag atcttaacga    600
caatatatgc aaaagatata taaagatgat aactaatata gttatactga gcctgatcat    660
ttgcatttcg ttagctttct ggattatatc aatgactgca agcacctatt atggtaactt    720
acgacctatt tctccgtggc gttggctgtt ttctgttgtt gttcctgttc tgatcgtctc    780
taatggcctt aaaaagaaaa gtctagatca cagtggggct ctaggagggc tagtcgttgg    840
atttatccta accattgcaa atttcagctt ttttacctct ttgctgatgt ttttcttgtc    900
ttcttcgaaa ctcactaaat ggaagggaga agtgaagaag cgtctagatt cagaatataa    960
ggaaggtggg caaaggaatt gggttcaggt gttctgtaat ggagctgtac ccacagaact   1020
ggccctgctg tacatgatag aaaatggccc cggggaaatc cagtcgattt ttccaagcag   1080
tactccgctt cctggatgtg tttgtctctc ttggctgcac tggcctgctc tgctggagac   1140
acatgggctt cagaagttgg cccagttctg agtaaaagtt ctccaagact gataacaacc   1200
tgggagaaag ttccagttgg taccaatgga ggagttacag tggtgggcct tgtctccagt   1260
ctccttggtg gtacctttgt gggcattgca tacttcctca cacagctgat ttttgtgaat   1320
gatttagaca tttctgcccc gcagtggcca attattgcat ttggtggttt arctggatta   1380
ctargatcaa ttgtggactc atacttaggg gctacaatgc agtatactgg gttggatgaa   1440
agcactggca tggtggtcaa cagcccaaca aataakgcaa ggcacatagc agggaaaccc   1500
attcttgata acaacgcagt gaatctgttt tcttctgttc ttattgccct cttgctccca   1560
actgctgctt ggggtttttg gcccaggggg tgaactttat ttcatttcca caggttgaaa   1620
ctggtgagtc cagctaaatt tgcaattcca actttcatcc taagaataat aactgtaatg   1680
gcaaagcgga aatgccagtt cctcctgtat tccattgaga tgggatttca cattttcctc   1740
tcatcaactc ccctgtaata gctagcgtct ttctagygaa agagaagaat tcctagaact   1800
tatgcatttt tttcctgctg aatggaagtc ttgagcaatg aagctatatt gtccctacat   1860
attactatat attgaactga aagttcttac ataatcaatg tcaagttttg tcttattttg   1920
ttttgtttgt ttaaaccagt gtaggaaata aaagtgatga tatttaaaat agttctcagt   1980
tgaagcagag aaatgccact gtgctagttg cccaaatgtt gtatctattt taaatagttt   2040
aagctgatgt gtatgggagc ctaaacaagt gtagtatcct gaacttctcc cattaattgc   2100
tattcacaat tgggaaaagt gtggagattg gttcctagtg agttttgtgg cctactccac   2160
atttgttctt ccttcctcag ggttagtgat gaaaaaaagt aaatatcttt ttcatatgtc   2220
cattagaatg tatgaaaaaa atcattttaa ctaaaagcaa aagaatttta tcttatatct   2280
aaaaaatata taacttacta tatgtttcag ttgctctctg aacaaaaatt atcttcaatt   2340
taatatgtgg aatgtgtttt ctagctttct ttgaattatg tatggcaacc tggtttagca   2400
ctggcatcct gaacagttaa gagtcactgg gaaattattg tatttcttta taaatttact   2460
gtcatatcaa ttgctggaaa atgctatgat ttttctatta ttaccttcta agttgtattc   2520
tctcttacac tgtagcctca actaaggcaa ttctgctatg tttgttcttc actatgattt   2580
actgtgtgcc aaaggagttt tgacagggta cagagtattt tactaaaagt atttttaaat   2640
gtttctcatg tgatttctgt accttcttcc tcctgcccct tttgcttttt taaagaaact   2700
ggggaaggat ttatgaatac accacc                                        2726

<210> 902
<211> 1011
<212> DNA
<213> Homo sapiens

<400> 902
cggaagttst ggactgcagt tgagtggaaa tgggcaacgg cgggcggagc ggcctgcagc     60
aggggaaggg gaacgtggat ggggtggcag cgactcctac tgctgcctcg gcctcctgcc    120
agtacaggtg catcgaatgc aaccaggagg ccaaagagtt gtaccgagac tataaccacg    180
gtgtgctgaa gataaccatc tgtaaatcct gccagaaacc tgtagacaaa tatatcgagt    240
atgatcctgt tatcatcttg attaatgcta tattgtgcaa agctcaggcc tacagacata    300
ttcttttcaa tactcaaata aatatccatg gaaaactctg catattttgt ttgctttgtg    360
aagcatacct gaggtggtgg cagcttcaag attccaacca gaatactgcc cctgatgact    420
tgatcagata tgctaaggaa tgggatttct atagaatgtt tgcgattgct gctttagaac    480
aaactgccta ttttattggc atttttacct tcctgtgggt agaacggccc atgacggcaa    540
aaaaaaagcc caacttcatt ttgctgctga aagcattatt attatctagc tacggaaaac    600
tcttgctgat tccagctgtc atttgggaac atgactacac atctgtgtgc ctcaaactca    660
ttaaagtatt tgttcttaca tcaaattttc aggcaattag agtgacccta aacatcaacc    720
gtaagmtctc cttcttggcc gtgttgagtg gcttactgct ggaaagatca tggtctactt    780
cttccagagt atggaatggg atgttggaag tgattatgcc atctttaaat ctcaggactt    840
ytgaagagtt ttattcttct tcactatctg tggcatgacc agctgtatct gaaagagaaa    900
agacatgaaa tataaaccaa cctcctcatt tctgttgagt aaaatgaagc aagattggga    960
aacactttct gaaaaagaam gstgataccc acccccacaa tggcacccag g            1011

<210> 903
<211> 2590
<212> DNA
<213> Homo sapiens

<400> 903
tttttttttt tttttttwtt tggcattaga aaccttttat tgwgacaagg taaacagtgg     60
gctgaaaata ttacaggctg aaggaaggct gaggaaacca gtatgaaggc agctcaaatg    120
atgaactaaa tatattccaa aggtactatt tatacttaag gcagttttaa aagtgaggtc    180
ttaaccaaaa agcctttaca tggcattcaa aacaaaaaca aaaacaaaaa aaacacgggg    240
ggggggggtc acttaaatct cttggattga ctaaaagagc taaattatgt acccaaaatc    300
tgtacagcag gggcctgttt tcagcaggaa agcctatgta caagtaagaa cctcttactc    360
ttgtaacatt gtcctgtttt gttttgtctt ataagaatat ataactccta tcctcacaga    420
gttagtccat aaggcctcag tgacctcaca gaaatatgga gttaacctct actacagaac    480
tatttacact gcactgtaaa tacacatatg tgtgtccacc ctcacagcta agctgtcaat    540
gccttgagtg aaggggttac agctcattcg ttttgcatct acagtgacaa tgaataggca    600
ctcaatacat actttttttt gcatgaatga taaatgaaat gattttacat taccaccact    660
atttacatta acattcctac cattagccgt ctccaaaata aaaacacaaa attgctgcca    720
catgttcagc agttttcaca atacagtgtg tctggacttt ttaatgtaaa caaacatgct    780
tgatttacca attttcagag caaggacaca aacttagcat tcttctagga atggaaaact    840
tgccaggaag ttacttcatt ctttttctct ttttcaaaag tgcatctcgt agtgccaact    900
gtttttctcg gaaggaacgc ttattttttg accggacatt ctggctatac cgcatcatca    960
taaagttctt ctgttttttc ttctctttat ttgtcgaact ggaaaatgga tttgttttgg   1020
ttttcttcct cacaaattct tttcggtctg tctttccagc cattgcagtt gctagtcttg   1080
tctctttgtc agactttggc tttttatgaa ggcgttcaat gtcccgaaga gaaagtaatt   1140
cacccctggg ctcttcatca ctgtctattt caatgtattt cctcttctgg satttcccgg   1200
gggcagcatc aagttctttt ctcatttggg ccatgcggat tttctggaag tcttcctgag   1260
ttaaaactcg gctagtgctg atggctgcag ctttggcctt ccgctcctcc atgggcatgc   1320
tgttcagctt cttggagatt tcttgctgtt cttcatcgga agagtgttgc acatcaatcc   1380
attcaccatc agcatcctcc tcctcactga gactggtact ttcccatcca tcttcatcat   1440
tttcakcatt ctcttctttc tcaacttcca gaacttctgc tcctggaatg taatctttag   1500
catctaattc tccatattct tgtactcttg cttctatgga ggcctctgta ggcttacccc   1560
ggaatttctt ctgcagcatc tgaggattca gtgttcggaa gaggtgaatc aaagttctag   1620
cagacatcat tacattctta tccttgtgtg ttttatactg agccaggtct tggagaagtt   1680
ctwcagtcat ggccagagga catcgagctg ttatctcctt tatagcattg attcctactg   1740
tcatgacttc tccagagttc ttgtcggtaa caaaattgtt tgccacagtc ataagcaatg   1800
attgaataat ctctgggggt actaggtgat gagatgcttg tgcagcaaac agaaggatct   1860
tggttacttc tctttggtgg ggctgcagaa acctttgcaa aaagggatag aaatkgaaga   1920
ggaaaagctc atgaattccc accaatctgg agataaggtt catgagcatc atcttcactt   1980
cwaacctctc cttacagcac tcaagctgct ttagtagttt ttcygcaaaa tcttggggat   2040
catgaatcaa gtgaatggct gaaaagttaa acacctctgg ttttttcttc tttttttgtt   2100
tcttgagcac tttcattgcc ttttccaact ttttcttgtt tttggaactt ttcttccctg   2160
tagcatattg tactagcagg tctcttgctg ttggtccatc atcctcagat tcggagtcac   2220
tgtcctgttt ttcatcttca tctttcccaa gaaagaatgt caaagcggca actaatatct   2280
tggtgacctt agagaaacat gcagttgtga taacattgac agtttttgca tcattccaga   2340
tgttccttct gtagagttca atcattacat ctaaagacat cttggctgcg gttgcattgc   2400
tatctcttaa catggtgtac atgaaatttt gcaatactac attcacttta ttgttcttgt   2460
gttttgcatt tatattcttg atatcagtca caatatgtgt gtataaagtc tttcgcagaa   2520
gtttatcatg gcaacgaraa arttcaaaga agagttctag caggcttgat ggattgatga   2580
gaatcttatt                                                          2590

<210> 904
<211> 1865
<212> DNA
<213> Homo sapiens

<400> 904
aggcgacccg ggcttctgtg aacatggcgg taggctggga ccataacaca agcatgacta     60
tatgaaggaa gaggaaggtt ttcctgaaga tgaggcgact gaatcggaaa aaaactttaa    120
gtttggtaaa agagttggat gcctttccga agttcctgag agctatgtag agacttcagc    180
cagtggaggt acagtttctc taatagcatt tacaactatg gctttattaa ccataatgga    240
attctcagta tatcaagata catggatgaa gtatgaatac gaagtagaca aggatttttc    300
tagcaaatta agaattaata tagatattac tgttgccatg aagtgtcaat atgttggagc    360
ggatgtattg gatttagcag aaacaatggt tgcatctgca gatggtttag tttatgaacc    420
aacagtattt gatctttcac cacagcagaa agagtggcag aggatgctgc agctgattca    480
gagtaggcta caagaagagc attcacttca agatgtgata tttaaaagtg cttttaaaag    540
tacatcaaca gctcttccac caagagaaga tgattcatca cagtctccaa atgcatgcag    600
aattcatggc catctatatg tcaataaagt agcagggaat tttcacataa cagtgggcaa    660
ggcaattcca catcctcgtg gtcatgcaca tttggcagca cttgtcaacc atgaatctta    720
caatttttct catagaatag atcatttgtc ttttggagag cttgttccag caattattaa    780
tcctttagat ggaactgaaa aaattgctat agatcacaac cagatgttcc aatattttat    840
tacagttgtg ccaacaaaac tacatacata taaaatatca gcagacaccc atcagttttc    900
tgtgacagaa agggaacgta tcattaacca tgctgcaggc agccatggag tctctgggat    960
atttatgaaa tatgatctca gttctcttat ggtgacagtt actgaggagc acatgccatt   1020
ctggcagttt tttgtaagac tctgtggtat tgttggagga atcttttcaa caacaggtta   1080
acaaccattt cctttttgtc taatttctga aagtgttgct tatacttaag ttgcttcttc   1140
tcaaaggggc aagaagtata cagattttca tgtttcggtg tttaaatagc ttttgctyya   1200
attacaaaac tccaaaatta tattgactaa ccagtaaaca taactaattt cattgtattc   1260
aatgatgtaa ggtagattat ataatggtga gttggaaaga tcctgggtgt taacatcaga   1320
ttgaagtaga attgaatgta agttctgtca tttacttggt ggtagcttgg aatagatcac   1380
ctaccttttc tgaggttttc taatcagtaa aaatagcaat aataatacct aatttgcaag   1440
tgtgctatag gattaaatat gaaaatgcct agaaggcatt taagacattt ttaactgtac   1500
agtatgtaaa atcatatgtt atagtacttt gaattatgca atacatgaaa ctagatttgt   1560
aatcagtaac atgtttatga tttttgtcct gagatcctgg aattcgctaa gattatttgt   1620
cgaattgtaa tgatgaaaat tgggagttaa gtacaataga gaaaaaggaa acaattctat   1680
tttcatcttc agtccttatt cagtattaga tggagctggg tagtttatta tacttagaat   1740
catattttta aatgaatgaa tagctttyct ttcgaaattc tttgttagtg cttcatttca   1800
atctatttaa atttgtgttg ttgacatcat ttatttycca aattgtattg gtgtgggaaa   1860
ccttg                                                               1865

<210> 905
<211> 1734
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1703)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1715)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1718)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1732)
<223> n equals a,t,g, or c

<400> 905
gcgactgtca tggcggcggc cgcccccaat gccggaggct cggcccctga gacagcgggt     60
tccgccgaag ctccgctgca gtacagcctg ctcctgcagt acctggtggg tgacaagcgt    120
cagccccggc tcctggagcc tgggagcctg ggcgggatcc caagtccagc caagagtgag    180
gagcagaaga tgatcgagaa ggcgatggaa agctgcgctt tcaaggctgc gctggcctgc    240
gtgggaggat ttgtcttagg aggtgcattt ggggtgttta ccgctggcat cgataccaac    300
gtgggctttg accctaagga tccttaccgt acaccgactg caaaagaagt gctgaaagac    360
atggggcaga gaggaatgtc ctatgccaaa aatttcgcca ttgtgggagc catgttttct    420
tgtactgagt gtttgataga atcttaccgg ggaacatcag actggaagaa cagtgtcatc    480
agtggctgca tcacgggagg agctattggt ttcagagctg gcttaaaggc tggggccatt    540
ggttgtggag gttttgctgc tttctctgct gcgattgatt attacctccg gtgagagtaa    600
ttgcctgcag ggaaggatga tgccagcccc ggatccgggc tgctctctgg aggacagttt    660
ctgtaccaca ccagggcctt gcttcagggc ctgaagacat tcattttccc tcatgtcgtt    720
ggtattctga gggagctgcc tggcttctct gcctccagcc tttggggtag ccacactttg    780
ctgctcctgg actccagcca gccttcacag aggacgtccc gtgccagatt ctctcacagc    840
agatcgggag acaggatgtt gacatatagg aattcagctc cacaaagctt caggcctgac    900
cacagctggc cctctaggtt gtttggtgtt gtgggcacag aggtgacagt gtctctgcag    960
gcactcagga agctgttcta ccttggaact ccatgcaact atccgtctcg aataccaggg   1020
cagggcaagg cggactgatg ccgtccaacc aattatctca cttgttttgt gttctgtcat   1080
ccttgttttt tttttaaaaa tacactcccc tcccccaccg ccacacacct tacagttcaa   1140
aaggttggtt tatttgtatt ttattttcaa attccctatt ccaaaaatag tgccgggtgg   1200
cccaaagata acatctgaag ggaaagaatg agaaagctcc cagggaagyg ggggatgggg   1260
cgctgaggca gggttgttag aggactgtgt catcctcacc aagctcatta catctgccag   1320
ggcctgcctc aagaagccca gcccagcctt ttcctgggat gcagtgaaat cccatccatg   1380
aactcgatgg gcccctcctg tgccggccga gaggcacaca ctgccttcac gacgtgactg   1440
ctggacctgg ccgagcttga ggccacatgt gaagggtcct gctgtggtca tcttggtgac   1500
tcggtcacag cagctactgg ccaagatcag acgtcgctga ggggctgttc accaccatcc   1560
tcgttctcca gggtcaagga agtgttttaa catgtcgtgt tttcgacttg accttgtggt   1620
atttttcttg gcctagttgt gtgccatgga tattaaaaaa aaaaaaaaaa atccgtctac   1680
aaaaaaaaaa aaaaaaaaaa ccnggggggg ggccnggnac caaattcccc cnaa         1734

<210> 906
<211> 1383
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (170)
<223> n equals a,t,g, or c

<400> 906
cacagccccg acccaagcgc gtaatggccg ctggctatct tgggggagcc agctgttgga     60
ctatgcccca ctgccaggaa acaggcgccg gaaggttctc tgacaagatc tcgctttcct    120
agggcggtga aggcgttcaa aggtcgggaa ggggcgctgg gagaagcggn gcagcgctga    180
gccatgctcg cgaactgtgg gtctgtctgt gaagagaccc agtttcgtgg gaccacggtg    240
gcgcctgcgc tgrgagagtt cttcactacc acaaccaagg agggatatga taggcggcca    300
gtggatataa ctcctttaga acaaaggaaa ttaacttttg atacccatgc attggttcag    360
gacttggaaa ctcatggatt tgacaaaaca caagcagaaa caattgtatc agcgttaact    420
gctttatcaa atgtcagcct ggatactatc tataaagaga tggtcactca agctcaacag    480
gaaataacag tacaacagct aatggctcat ttggatgcta tcaggaaaga catggtcatc    540
ctagagaaaa gtgaatttgc aaatctgaga gcagagaatg agaaaatgaa aattgaatta    600
gaccaagtta agcaacaact aatgcatgaa accagtcgaa tcagagcaga taataaactg    660
gatatcaact tagaaaggag cagagtaaca gatatgttta cagatcaaga aaagcaactt    720
atggaaacaa ctacagaatt tacaaaaaag gatactcaaa ccaaaagtat tatttcagag    780
accagtaata aaattgacgc tgaaattgct tccttaaaaa cactgatgga atctaacaaa    840
cttgagacaa ttcgttatct tgcagcttcr gtgtttactt gcctggcaat agcattggga    900
ttttatagat tctggaagta gtattaatgc tcatcctgct gtggctgttg gcttcttaga    960
acaccaaacc gggagagatt tactttgaac attgtcagtt gcagcaaaaa tttactacac   1020
aagattattc gaagtgtata cggactaaaa gaggaagtgt tttagaatga gaagagatac   1080
tgtgtcttta ttgtgtgtgt gtgagtgcag gtgtgtgtct ttattatatt gaaaagctgt   1140
cactcagacc tggtttgaga tagaagagca ttttgtcctt ttgatagtta atagaaattg   1200
aaccagagtt ttcttatgtt tgcttgaaca gttgtgtaaa tcatacagga ttttgtgggt   1260
attggttgaa tatttgtaaa ccattcccta gcctacatat ttattactga attaactttc   1320
ctgataacca ttgcataatt acatttttct ataaaatgaa agattattac aamaaaaaaa   1380
aaa                                                                 1383

<210> 907
<211> 3878
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2078)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2079)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3847)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3869)
<223> n equals a,t,g, or c

<400> 907
tgacacgggc cccacaggca tcaagtatga cctggaccgg caccagtaca actacgtgga     60
cgctgtgtgc tatgagaacc gactgcactg gtttgccaag tacttcccct acctggtgct    120
tctgcacacg ctcatcttcc tggcctgcag caacttctgg ttcaaattcc cgcgcaccag    180
ctcgaagctg gagcactttg tgtctatcct gctgaagtgc ttcgactcgc cctggaccac    240
gagggccctg tcggagacag tggtggagga gagcgacccc aagccggcct tcagcaagat    300
gaatgggtcc atggacaaaa agtcatcgac cgtcagtgag gacgtggagg ccaccgtgcc    360
catgctgcag cggaccaagt cacggatcga gcagggtatc gtggaccgct cagagacggg    420
cgtgctggac aagaaggagg gggagcaagc caaggcgctg tttgagaagg tgaagaagtt    480
ccggacccat gtggaggagg gggacattgt gtaccgcctc tacatgcggc agaccatcat    540
caaggtgatc aagttcatcc tcatcatctg ctacaccgtc tactacgtgc acaacatcaa    600
gttcgacgtg gactgcaccg tggacattga gagcctgacg ggctaccgca cctaccgctg    660
tgcccacccc ctggccacac tcttcaagat cctggcgtcc ttctacatca gcctagtcat    720
cttctacggc ctcatctgca tgtatacact gtggtggatg ctacggcgct ccctcaagaa    780
gtactcgttt gagtcgatcc gtgaggagag cagctacagc gacatccccg acgtcaagaa    840
cgacttcgcc ttcatgctgc acctcattga ccaatacgac ccgctctact ccaagcgctt    900
cgccgtcttc ctgtcggagg tgagtgagaa caagctgcgg cagctgaacc tcaacaacga    960
gtggacgctg gacaagctcc ggcagcggct caccaagaac gcgcaggaca agctggagct   1020
gcacctgttc atgctcagtg gcatccctga cactgtgttt gacctggtgg agctggaggt   1080
cctcaagctg gagctgatcc ccgacgtgac catcccgccc agcattgccc agctcacggg   1140
cctcaaggag ctgtggctct accacacagc ggccaagatt gaagcgcccg cgctggcctt   1200
cctgcgcgag aacctgcggg cgctgcacat caagttcacc gacatcaagg agatcccgct   1260
gtggatctat agcctgaaga cactggagga gctgcacctg acgggcaacc tgagcgcgga   1320
gaacaaccgc tacatcgtca tcgacgggct gcgggagctc aaacgcctca aggtgctgcg   1380
gctcaagagc aacctaagca agctgccaca ggtggtcaca gatgtgggcg tgcacctgca   1440
gaagctgtcc atcaacaatg agggcaccaa gctcatcgtc ctcaacagcc tcaagaagat   1500
ggcgaacctg actgagctgg agctgatccg ctgtgacctg gagcgcatcc cccactccat   1560
cttcagcctc cacaacctgc aggagattga cctcaaggac aacaacctca agaccatcga   1620
ggagatcatc agcttccagc acctgcaccg cctcacctgc cttaagctgt ggtacaacca   1680
catcgcctac atccccatcc agatcggcaa cctcaccaac ctggagcgcc tctacctgaa   1740
ccgcaacaag atcgagaaga tccccaccca gctcttctac tgccgcaagc tgcgctacct   1800
ggacctcagc cacaacaacc tgaccttcct ccctgccgac atcggcctcc tgcagaacct   1860
ccagaaccta gccatcacgg ccaaccggat cgagacgctc cctccggagc tcttccagtg   1920
ccggaagctg cgggccctgc acctgggcaa caacgtgctg cagtcactgc cctccagggt   1980
gggcgagctg accaacctga cgcagatcga gctgcggggc aaccggctgg agtgcctgcc   2040
tgtggagctg ggcgagtgcc cactgctcaa gcgcagcnnc ttggtggtgg aggaggacct   2100
gttcaacaca ctgccacccg aggtgaagga gcggctgtgg agggctgaca aggagcaggc   2160
ctgagcgagg ccggcccagc acagcaagca gcaggaccgc tgcccagtcc tcaggcccgg   2220
agggcaggcc tagcttctcc cagaactccc ggacagccag gacagcctcg tggctgggca   2280
ggagcctggg gccgcttgtg agtcaggcca gagcgagagg acagtatctg tggggctggc   2340
cccttttctc cctctgagac tcacgtcccc cagggcaagt gcttgtggag gagagcaagt   2400
ctcaagagcg cagtatttgg ataatcaggg tctcctccct ggaggccagc tctgccccag   2460
gggctgagct gccaccagag gtcctgggac cctcacttta gttcttggta tttatttttc   2520
tccatctccc acctccttca tccagataac ttatacattc ccaagaaagt tcagcccaga   2580
tggaaggtgt tcagggaaag gtgggctgcc ttttcccctt gtccttattt agcgatgccg   2640
ccgggcattt aacacccacc tggacttcag cagagtggtc cggggcgaac cagccatggg   2700
acggtcaccc agcagtgccg ggctgggctc tgcggtgcgg tccacgggag agcaggcctc   2760
cagctggaaa ggccaggcct ggagcttgcc tcttcagtat ttgtggcagt tttagttttt   2820
tgtttttttt tttttaatca aaaaacaatt tttttaaaaa aaaaagcttt gaaaatggat   2880
ggtttgggta ttaaaaagaa aaaaaaaact taaaaaaaaa aagacactaa cggccagtga   2940
gttggagtct cagggcaggg tggcagtttc ccttgagcaa agcagccaga cgttgaactg   3000
tgtttccttt ccctgggcgc agggtgcagg gtgtcttccg gatctggtgt gaccttggtc   3060
caggagttct atttgttcct ggggagggag gtttttttgt ttgttttttg ggtttttttg   3120
gtgtcttgtt ttctttctcc tccatgtgtc ttggcaggca ctcatttctg tggctgtcgg   3180
ccagagggaa tgttctggag ctgccaagga gggaggagac tcgggttggc taatccccgg   3240
atgaacggtg ctccattcgc acctcccctc ctcgtgcctg ccctgcctct ccacgcacag   3300
tgttaaggag ccaagaggag ccacttcgcc cagactttgt ttccccaccg cctgcggcat   3360
gggtgtgtcc agtgccaccg ctggcctccg ctgcttccat cagccytgtc gccacctggt   3420
ccttcatgaa gagcagacac ttagaggctg gtcgggaatg gggaggtcgc ccctgggagg   3480
gcaggcgttg gttccaagcc ggttcccgtc cctggcgcct ggagtgcaca cagcccagtc   3540
ggcacctggt ggctggaagc caccctgctt tagatcactc gggtccccac cttagaaggg   3600
tccccgcctt agatcaatca cgtggacact aaggcacgtt ttagagtctc ttgtcttaat   3660
gattatgtcc atccgtctgt ccgtccattt gtgttttctg cgtcgtgtca ttggatataa   3720
tcctcagaaa taatgcacac tagcctctga caaccatgaa gcaaaaatcc gttacatgtg   3780
ggtctgaact tgtagactcg gtcacagtat caaataaaat ctataacaga aaaaaaaaaa   3840
aaagggngcc gtctaaagat caacttctnc cttgatca                           3878

<210> 908
<211> 4039
<212> DNA
<213> Homo sapiens

<400> 908
aattcggaac gagggtgaag cacaaggatt aagttggaaa agctgtaaat tgcatgtgca     60
tatttgtcta ttttttctat aagttttatt gcaagaggta aagaagaaaa ctatatatat    120
atatcttatt tagataatct cagtaccttt tctggcattt ttgccctgta taggttgact    180
tggcaattcg gcctttttag aggcattaac tactcctcgt aagtgttgca tttacatggc    240
tgtttagaaa actgctgccc aaatttattt tatatttttg tacagattct gcagtttatg    300
atattgtttt ctaaaaacaa atgctgttta tacatatgag atagctattt tgataggatt    360
tgctcacata gttcctgcaa acttcagatg tacaagttgc acttgtactt ttatagagtt    420
gtaatgtttt atatgtgtat ggtgcaagag aaaattggat caaatcaatc tgcagttgat    480
gtccccaaat gcaaacacag gcacacacat gcacacaccc ataaacacac acacagtgct    540
ttaagaaagg gccaggtgat atcacaccca aatttcacaa gcactgaccc cctggcacca    600
acacccgcca gtactgtgac ttccaaagcc agagccacat gtgctcatca aacttgcatt    660
aagcagttgg cgggagatgg ctgtggagct gggggtttaa gtgatggttc tcttttgctc    720
cctcttytga gggtaaagct actgtctttc ttaagagtgt atttatgcca agtttgcgct    780
tttaattgtt tttattttgt tttttaatga aaacccagat ctttcctttt tggcataatt    840
tttatgatga cctgaaattt tacatccgaa caaaatttta catccgaaaa gcaaccaact    900
tcttcatgga actcagccct gttgcaatgc ttagggccct taaagaagaa aatctcccca    960
kaaggcatcc atcatgttgc ttaattgtct tctgcagctt cctttcccta gagctttccc   1020
tgtgttgcta agagctgaaa atggcatctt cgtgatcacc acagtgagct tggctcgcct   1080
cggccggccc gggatgcact cttacaacat gtgtgactct tgaacctgga gttcatcaca   1140
ttacgtcaca gcttcccatc tggttgcttt cctgagtcag ctacttcaca cttgtcaagg   1200
ctgttttacc ccaaaactca gacaggactt tctatgcatg ttttccctcc tccccccaat   1260
tcccccccca tcaccttatc tcccaggaca cacttgagaa gtagcttttt attcctagtg   1320
gtgtacattt aattttaaaa aggttgcaat gtatcatgct tgttgccgaa actgtttatg   1380
gccttcttgt ttcagttttt tcttttcttc caatggtact ttagctgttg agtgcaggtt   1440
acaacctata ttgttatgca gatggcttct ttaggaataa cttttatatt tatttaaaaa   1500
tttttaaatt atgggatgtt ttgttgttgt tgttgtcttt gttgttggtc atttgtcaat   1560
attcagtcac caattctgct cacttcttgc catggataaa attgggtctt tctggctaat   1620
taaaaaagac aactttataa aatggcactt taagcaagcc atagttagtt ttatttttgt   1680
aatgcacatg gcaaagcaaa gacgtttgtg atgaaggaac tgctcatcta agcaaaagat   1740
ttgagtatga tatgataaag gctttctaca ttctaattta ctttttcccc ccacttgaat   1800
gtgttttaaa ggctaattat cagctcagta gagcagtgag aaactgatca aattgcactt   1860
gttctcctac aagcaacctc cacgcagaca cctcgtactg ctacaggtgt gtcatttcct   1920
ttaataggac cagggaccat gtaactgagg tgagggttgt agtaratgct tccagtgtca   1980
gtatgcctgt taattttaag agcttccctt tcttgcagag aacaagtctg cccagattcc   2040
atgctttcta taactggagg acctggcaaa cctgccgcat gctgcacaca tctacctacg   2100
tacacatata caatagtatt gatgattctg aacaataaca gggtaaaaca gttggtttgc   2160
cattgttaaa aactgattta cagtaactta caacaactgt acttttgttg gattagcaaa   2220
tcatgtgttt aaacaaatcc catatgttgg gcaacagttc aaataagcac ggagaagtgt   2280
tgcccaaact tggttctctg actcttatgt atttgtaagg ctgggcttca aaatcaaaac   2340
aaaaacccca aaaacagcag gcaaatgctt tttaactctg acaccgttgc cataaatccc   2400
tgatactcaa agtctaacaa gaaagacatg gaaaattagc agcccatttt cagaaagatc   2460
aaaatgatct agggttctaa ttgcttttgc atcctattct tacaaagtga tgtcccaaca   2520
gggaacagta ggagctggag tgggatctcc aagtcccagt ttgagtgtgg gatgtgcttc   2580
cagcagtgcc ttccctttat gaaagacatc acatggcatc cagggccagg caggcagctt   2640
gaggtgcctt tacgagaaaa ccgagctggg gctgggagag gacagttatt gacactgatg   2700
tgcaatgaag tgacaagatg agagcagaat cgtaagagct ttgaatttga agtgagtttt   2760
ttccccccat aagttattta ttcctttttt ctgtgtaaat atatttattt tactgtggag   2820
cgctaacatc tggatcgtaa catgtgcaga atgtatggta ggaatgtatt ctcttgtagg   2880
aatgtaaatc tgtattaaaa gggggtccaa gccaggcccc caggtcttct cattgtatgc   2940
acagtccgca ttcattttta ctcttctcta atatgggtct atttgaaata tgcaaaaggt   3000
atgaggaatg ttttaatacc tccaaatttt taagaaaagc atcaaagggt tgatattttt   3060
taaagttttt ttagtagcac tttctctgga tgacagaagg ggcaaccaca tgggcaccct   3120
tgttcatacc aaagggtgag cagtggccag agcctcctct gcacctctcg agtgtcttta   3180
ccaattgagc tttttatcgc catagcccct tggagtgccc cagctgccct gaggtcaatc   3240
aaggaaaatt tcttaatgaa ataagctcca aagagccaaa gtatcaactt acagatcgtt   3300
tttaaagctt aaatttatga accacctttg tggtaaacaa tgaattatga ataccgcagg   3360
gcagccttct taaatgacaa atgtaaaaaa aaaaaaaaaa aaactctact tcgtgcagca   3420
attgctactc tatacgaatt gtcttaattt gaaaaccttg ctgttacaaa ttggaccttt   3480
atacattttc tgaaaacaat gaaaagagta tatttaacct tttctggctg taaatggtta   3540
ccttcctgta actgccccgc acctggaggc atggagttgt gtgcatcctg cttatgtaca   3600
attgttttca gtgtttctaa gaatgagtct gaatggttct tgaaaattag ccaggatcaa   3660
atgctattgc agacaaagcc aataaaaagt tggacttctt ttggggataa caagttttgg   3720
aagagaaatg caggccatat gtgcgcatga ccgagatttt gaaaaaagat gtacatagtg   3780
acatgtttgg tgcatggttt ttgaggaggg cttttgtcaa aaaggaggta taacctttcc   3840
cccacagacc tgagagctgt gccttttcta tgcaatatta cagacgttac atcggaaccc   3900
agatggctgt attcacatgt aggtttgggc tgtaatctaa acaattggac agattaaatg   3960
tacatggaaa tgagcagtct tacttttgta gttttatatt atacaataaa cagttaaaag   4020
atgaaaaaaa aaaaaaaaa                                                4039

<210> 909
<211> 2924
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2892)
<223> n equals a,t,g, or c

<400> 909
gaggccaaga ttcgcacgag tttttttttt ttttttaaaa aatcacatag aactttatta     60
aataaaccag tagaaaggct cctatttaca tccaggttgt cagtttaagc tcaagtaata    120
tgcaaggcac aattcttcct ttctccagct ttagaaaaat caaccacatg gcccagccct    180
gaaggactga agggagcttg tgcgggatcc cgtcatcctg gactctccac acagcgtcca    240
cgcatggatg gccatgggca tgagtctctg gatctccctg agggtagccc agcctcggcc    300
tggagcacag gggcctgtga tctgagaatc tcagatccag aatcaggagc tgggaagaga    360
ggacttttcc aagggtctcc tcccccaggc cctggggagt cccttctgga tgggcaggcc    420
ctgggctggy ggccgccctc catcattggc ccaggccggg ctctagggcc kgctgggaag    480
ctgtctgggg ccctgcgcct gatgagctgc catgaaagtg gccgcctctc acactggcag    540
gcggtggctc agatctgctg aggttctgga gtggcacagg aacaggagga gcaaatgaca    600
ctgggtcttt gtgctgaggc aggacacagc ggctttccga aacacacaca cagaaaatat    660
gactcctgct gccatctcaa ggacattttc ctaaggacag tcctggtgtc ctgatggagt    720
gaaagggatc acacgtggga tgtcccagca gggcctaagc caagtccatc agatgtctca    780
acggcttatg aaacaaaaac agaggactga agtctgttca cagtggccca tggttgggca    840
gcagccctgg cctccaggtg ctggttcctg aggcttccct tgcggcagtg gcgcagatac    900
agggacactc atgtcccatt gctcctcaga agtcctagca gcagccagac taggggcaaa    960
gtaagttttc acagggggaa aaaccccacc aaaaaccccc taaagtaact ggacaatcct   1020
ttccctgaga ccactacagt aacatcaccc acagacaact tctaaagagc acttctaact   1080
gctcaaagtc ttgagaaggg aaagatttta gcaaggctag gaaaataaaa atgcaacagc   1140
acattgtcca gaaaccctag acaaccatgc aaaaaggaat gagccaaaaa gtcttagctt   1200
tgtaagactt gaaaggaaaa aaacacacat ttaaaactcc tacataaaat gagctaatgg   1260
gcagagccga aactacagct ctgtgtgaag agacggcagt gaagctggcc tggggccggg   1320
gcactcatct ggaggggctt gttccagtgt gaatgcagca gggatgttcc atcttggggg   1380
tgcacgaggc tcggctgaga cccatcctcc gggaaccttc acgcggccta gtgggaggca   1440
taggctgggc tccacagccc tgagggaggg ctggctttgc gagcaggagg caatgcattg   1500
ggagatgtgg gtgatgaggc agcgaaatag tgggggctgt gtccagggct ggctcgaggc   1560
gtgagggctg caggcacagc aagatcccgg ggcgtgcaga cagtgtggta ggctatgatc   1620
atgaccgctg tcccagccaa cagggcgaag agcgtgaaga acatgacctg gtaggaatcc   1680
aggaagtgct ggaagaggct ggctccataa ggaccgggcc cacggcgatc caycacaaaa   1740
gccactgtca ctgggatggc aatggcttgg ttggtcacgg ggctggagaa ggtcagggta   1800
gtggacagag gcccttggct gccagccgcg gggtccaaga cgccgaccgt gtatgtgatg   1860
aagctgggcc acccaaaaga cttctccttt gcgaatgcca gcacggccgg ggacccggat   1920
ttcacctcca agttctccag aacctccggg gcaccaaaga ccctgatctc ggaactggtg   1980
tagtggttgc tcaaaaggat ttcagcctgg tcggcgaaga gacctgggct gaagggcacc   2040
tcggccccca cctgctctgt ggagaagtgg ctgctggaga gggaggcact gaccaccaga   2100
gctgtcttct tcatgctcag gtgcttccgc tgcttgtccg tcagcctgtg cattgtgatt   2160
gagcagaagt actggccgag agcagtgtca aactgtggct ccacggtgaa cacatcttga   2220
gatgggaaat caaagacggc cggcttgaac tgggactggc agctgatgag ggtctctggg   2280
tgcaaggcct ggatgacttc cctctgggtg ggggtgcact cgcctctcag gttagagctt   2340
ctgtctccca cggcaacaat cactttggag gctgtagcct cctggaagct ggtctggatg   2400
gggtggaggt gacgggccat gatcctctga gggacgctga ccaccacctc cttgtaggtc   2460
ctcaggtgcc cagcgacctc atagtaaacc gtcacggatc ccacggcccg ggccacagcc   2520
acacccgtct tggggtcgat gtggaggatg ctgttggccg aggagctcca ggttcctgag   2580
aggccttcca ggctggtcag aacagtggcc agacagagca cgtcccccac caccatggcc   2640
ccagacagct ctggggagat ggcctgtagg acaggcaggg gcatgaagtc cgagaggccc   2700
gggtgctctg cgtcccacac acggagcagt gtcaggccca cgctgactgt gcggacaaca   2760
caggtgttgt tggtggggcc cttcccgatc tgcacaaagt cgtctctgtt agtggcaaag   2820
ttgaggaccg aactgtgagc atggaagaca tctccagagt tgtcgyggaa gtggacagtg   2880
aaggtcaccg gncattccca aaggcaccgg ccaccaaggg cctc                    2924

<210> 910
<211> 1156
<212> DNA
<213> Homo sapiens

<400> 910
ttattgaagg gggtgcatcg gtcgatgaaa gcgccatcac cggggaatcg gcaccggtga     60
tccgtgaatc cggcggcgat tttgcctccg tcaccggcgg cacgcgtatt ctttctgact    120
ggctggtgat tgagtgtagc gttaaccccg gcgagacatt tctggatcgg atgatcgcga    180
tggtggaagg cgcacagcga cgcaaaacgc cgaacgaaat tgccctgacc attctgctga    240
ttgccctgac tatcgtcttt ttactggcaa ccgccacgct gtggccgttt tccgcgtggg    300
gcggtaatgc agtcagcgta acggtactgg tggcgctgct ggtctgtctg atcccaacca    360
ctattggcgg cctgttgtca gcgatcggcg tcgccgggat gagccggatg ctaggcgcga    420
atgtgattgc caccagcgga cgtgcagttg aagcggcagg tgacgttgac gttctgctac    480
tggataaaac cggcaccatc acactcggta accgtcaggc gtcggagttt atccccgcgc    540
agggcgtgga tgaaaaaacg ctggctgacg ccgcacaact ggcttcgctg gctgatgaaa    600
cgccggaagg ccgcagtatt gtgatcctcg ccaagcagcg ttttaacctg cgcgarcgcg    660
atgtgcagtc gctccatgcc acctttgtac cgtttactgc gcaaagccgg atgagcggga    720
tcaacatcga caaccgcatg atccgtaaag gttctgtcga tgccattcgt cgccatgttg    780
aggctaacgg tggtcacttc cctaccgatg ttgatcaaaa agtcgatcag gttgcgcgtc    840
agggagccac gccgctggtg gtggtggaag gttctcgtgt gctgggcgtt attgcgctga    900
aagatatcgt caaaggcggt attaaagagc gcttcgccca gctgcgcaaa atgggcatta    960
aaacggtgat gattcaccgg cgataaccgt ctgactgccg ccgcgattgc tgcggaagcg   1020
ggtgtcgatg attttcctcg ccgaagcgac accggaggcc aagctggcat tgatccgtca   1080
gtatcaggcg gaaggtcgtt tggtagcgat gaccggcggc ggcggatttg gcggctgtat   1140
cgtcgcgctg aycccg                                                   1156

<210> 911
<211> 1697
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (969)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1004)
<223> n equals a,t,g, or c

<400> 911
ttaggtgaca ctatagaagg tacgcctgca ggtaccgngt ccggaattcc cgggtcgccc     60
acgcgtcckg gctgtcagag tcagggtaac acacaccaag agtggagtgc ggccagcaag    120
tttgagacct gcccgccctc ctcgcagctc tgctctgtgt cctcaggaag tcacagagtc    180
tactgaggca aggagagggt gattctttcc ccaaatccct tcttccctgg ttcccaaacc    240
aaagacagcc tgcagccctt tctgcatggg gtgctctgtt gacaggcttc ccagatccct    300
gagtctctct ttccttcctc ctcgatcttt agttgtccac ggtcaattca gtgcttccat    360
tgggggacag tcccctccgg gatgacctga ttcacctcca gcccagggaa tggaatctag    420
aggaatacgt ggggtgggtc tggacaagga gcggcaggaa tcaccaccca tctccagctg    480
tggagccctg tggaggggaa ggggaagctt ggggttcaga gggractctt ccaggagagg    540
ggtgcccagy ggaggtaaag atgatagagg gttgtggggg gtctctagtt gaatgttttg    600
gcccatgact ttggaacatg gctggcagct tccagcagaa gtcamgctcc ccatccccca    660
ggggacatrg gacctttttc ctgcttcctg gtcactttca aagaactatt tgcgcaatct    720
gtgggtctgt ggattcacgg ggctttctgt gtgggtgctg cagttgcttt tgtctgcagc    780
agcaggacac atctttcctc ttactcagcc ctttatggcc catggggaac tccgtggctc    840
agggagagct gaactccagg ggtgtgacct gggacrggtg ggcctgaggt gcccagctca    900
gggcagccag gtggctcatg ggctgtagtg agccagctcc ctgggggaaa aggctgtggg    960
ccgttaganc atcctccagg acaggtgacc tctatgaggt cacntacggc tgtggcctgc   1020
aggctccttc cagcccagag tggcccagta gagcaaggca gacagtgacc tccacccccg   1080
cagccctctt aaaaggccag tactcttggg ggtgggggga gggtttagaa agcatttgcc   1140
catctgcctt tctttccccc agcccccacc cgctttgaat gtagagaccc gtgggcactt   1200
ttccttttgt ggtggggggt gcggaggagg tacccccacc cctggcacag ccgcctggaa   1260
tgcaggactg tcactgctgt tcgggtgatg acctcgttgc caagctcctc ctgtcccctt   1320
gttctggggg caggcgctgt gcttctgtga ggtggtttag cttttgcttt cgaagtggcc   1380
agctgcggcc accaggtctc agcacaagag cgcttccttt gcacagaatg agcttcgagc   1440
tttgttcaga ctaaatgaat gtatctggga ggggtcgggg gcacgagttg attccaagca   1500
catgcctttg ctgagtgtgt gtgtgctggg agagtcagag tggatgtaga gcgcggtttt   1560
atttttgtac tgacattggt aagagactgt atagcatcta tttatttaga tgatttatct   1620
ggtaaatgag gcaaaaaaat tattaaaaat acattaaaga tgatttaaaa aaaaaaaaaa   1680
aaaaaaaaaa aaaaaaa                                                  1697

<210> 912
<211> 2390
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1203)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1856)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2361)
<223> n equals a,t,g, or c

<400> 912
ggcacgaggg acgtcacccc ggagaaggtg cccacccaca tcgtggacta ctcagaagcc     60
gagcagacgg acgaggagct gcgggaggag atccacaagg caaacgtggt gtgtgtggtg    120
tatgacgtct ctgaggaggc caccattgag aagattcgaa ctaagtggat cccactggtg    180
aatgggggga ccacgcaggg gcccagggtg cccatcatcc tagtgggcaa caagtcagac    240
ctgcggtcgg ggagctccat ggaggccgtg ctccccatca tgagccagtt tcccgagatt    300
gagacctgcg tggagtgttc ggccaagaac ctgaggaaca tctcagagct gttctactac    360
gcccagaagg ccgtcctgca tcccacagcc cccctctatg accctgaggc caagcagttg    420
aggcccgcgt gcgcccaggc gctgacgcgc atcttcaggc tctcagatca ggacctggac    480
caggcgctca gtgacgaaga gctcaacgct ttccagaaat cctgctttrg gcaccccctg    540
gccccgcagg ccctggagga cgtgaagacg gtggtgtgca ggaacgtggc gggcggcgtg    600
cgggaggacc rgctgaccct ggatggtgag gccgggtgcc cgcctgtgcc tggggagtgt    660
ggggaggggg ctgtgcctgg tgctccccct gctttgtctc ggtgcaggtt tcctcttcct    720
gaacacgctc ttcatccagc gcggccggca cgagaccacc tggaccatcc tgcggcgctt    780
cggctacagc gatgccctgg agctgactgc ggactatctc tcccctctga tccacgtgcc    840
ccccggctgc agcacggagc tcaaccacct tggctaccag tttgtgcaga gagtgtttga    900
gaagcacgac caggaccgcg acggcgccct ctcgcccgtg gagctgcaaa gccttttcag    960
tgtgttccca gcagcgccct ggggccccga gctcccacgc acagtccgca cagaggccgg   1020
ccggttgccc ctgcacggat acctctgcca gtggaccctg gtgacctacc tggacgtccg   1080
gagctgcctt ggacacctag gctacctggg ctaccccacc ctctgtgagc aggaccaggc   1140
ccatgccatc acagtcactc gtgagaagag gctggaccag gagaagggac agacgcagcg   1200
gancgtcctc ctgtgcaagg tggtaggggc ccgtggagtg ggcaagtctg ccttcctgca   1260
ggcctttctc ggccgcggcc tggggcacca ggacacgagg gagcagcctc ccggctacgc   1320
catcgacacg gtgcaggtca atggrcagga gaagtacttg atcctctgtg aggtgggcac   1380
agatggtctg ctggccacat cgctggacgc cacctgtgac gttgcctgct tgatgtttga   1440
tggcagtgac ccaaagtcct ttgcacattg tgccagcgtc tacaagcacc attacatgga   1500
cgggcagacc ccctgcctct ttgtctcctc caaggccgac ctgcccgaag gtgtcgcggt   1560
gtctggccca tcaccggccg agttttgccg caagcaccgg ctacccgctc ccgtgccgtt   1620
ctcctgtgct ggcccagccg agcccagcac caccatcttc acccagctcg ccaccatggc   1680
cgccttccca catttggtcc acgcagagct gcatccctct tccttctggc tccgggggct   1740
gctgggggtt gtcggggccg ccgtggccgc agtcctcagc ttctcactct acagggtcct   1800
ggtgaagagc cagtgaggcc cctggtaccc aagccccctc ccctgacctg ggtgtngctm   1860
gctgctgggg ctctgcaggg gcagcacagc tggggtgcag gscaggctgc cactccggga   1920
acgcctttgc gccgggactt tttgtttctg aaggcagtcg atctgcarcg gggccttatg   1980
ctgccatgca mtgccctggc tyctgccgga cccccagggt gggccgtggc aggtggctga   2040
gcaggagctc ccaagtgccg gccaccgctg tcagggattg cccacccctg ggcatcatgt   2100
gtgtggggcc ggggagcaca ggtgtgggag ctggtgaccc cagacccaga attctcaggg   2160
ctctaccccc ctttcctggt cctaggtggc cagtgggtat gaggagggct ggaaggcaga   2220
gctttgggcc aaaagcaggc gttggggggt cccccctcaa gtttggagcc gtttccgtgg   2280
ttgtagcaga ggaccggagg ttgggttcct gattaaactt cactgtgtgt tttctatctc   2340
ggatcccagt ctctgaagac nacttgcttt gattcaacct aaaaaaaaaa              2390

<210> 913
<211> 1410
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (240)
<223> n equals a,t,g, or c

<400> 913
gcccacgcgt ccgcccacgc gttttntaaa accctgtctc tactaaaaat acaaaattag     60
ctggatgtgg tggtgcacgc ctgtaatcca gctactcggg aggctgagtg aggcaagaga    120
atcgcttgaa cctgggaggc acaggttgta gtgagtcgag atcacgccac tgcactccag    180
gctgggtgac agagtgagat attgtctcaa aaagaaaaaa aaaaaagaaa aaaagagaan    240
gggagtaact gcaaaatggc agagctgtct gatcccaaat gacacttgtt ctctctgctg    300
ctgggcacct tcacgctttc ctatgggtgt cacccacctc ccaccctgag gtattccacc    360
tcctacctgg atgcgagcag cagtttccct gcggaaatcc tccttcaggg cagcttcacg    420
gcggytyact akcccctcca gcagcgccag ggtgtcctmg tggctcaggc caccaccacc    480
tccctggcca ggagcccctt gccgcagctc cagacgttcc agccgcatgg cctccttctg    540
ccagttggag gaaaattcag cagcaagagc ttccagacgc cgctccagag agtgtacccg    600
ggacataaca cgctgctcag cctggaaatg tggcgatgag tctctggctt cccagccctc    660
atccggcctc ctgctgtcct tcgctgccca ccaggaaacc aaagcagggt ggaatgtctg    720
cagcccatag gggtagaaat accaagcacc atacgtcagg cacgtcagca agagcagcgg    780
cagcaggaac cagaggaacg tcttmaggga cgagaagcgc ctggttaaaa cgaagacgtc    840
aaggagggag gcagctgtgg tcaggcggta ccaggtggtg ccagcccacc agtagagaag    900
tctgaagagc cggcctggcg aagtggccac catccagagt aaggagcccg cccgtgagac    960
ggcgcttcgg agccgcgagc tggaactctg ctggtccaca tccgagtagc ccacgtagtc   1020
gtcctcagag gagtagcccg aggaagagcc caggaagtcc tcggtggcct tgcgccccac   1080
aagcccgctg gccctgctgc tctctgagcc acccgtgcct ctcctcctcc gcacccgcag   1140
gtcctcaccc cagttggcgt caccatgcag ttcctccagg gagctcctgg gtgggaacca   1200
ggactcgtgg accagcgact cactgtagta ggaggtgtgt gcatcagagg acgggcccag   1260
ctgtggcgct ggggacaggc gcttcatgtt gctggatttc ctcttcaagg tcctgagagg   1320
actgtcttta aacagggtgc tctgactccc agccaccgag ctccctccgc tgctgctgct   1380
gccgtcatcg tcaccctggg agtagcgcgc                                    1410

<210> 914
<211> 1613
<212> DNA
<213> Homo sapiens

<400> 914
ggcgggccag ccaagatggc ggcctcatgc ttggtcctgc tggcgctgtg tctgctgctg     60
ccgctgctgc tgctgggagg atggaagcgc tggcgccggg ggcgggcggc ccggcatgta    120
gtagcggtgg tgctgggcga cgtgggccgc agcccccgta tgcagtacca cgcgctgtcg    180
ttggccatgc acggcttctc ggtgaccctc ctggggttct gcaactccaa accccatgat    240
gagctcttgc agaacaacag aattcagatt gtggggttga cagaacttca gagtcttgca    300
gttgggcccc gagttttcca gtacggagtc aaagttgtac ttcaggctat gtacttgctg    360
tggaagttga tgtggaggga gccaggtgcc tatatctttc tccagaaccc cccaggtctg    420
cctagcattg ctgtctgctg gttcgtgggc tgcctttgtg gaagcaagct cgtcattgac    480
tggcacaact atggctactc catcatgggt ctggtgcatg gccccaacca tcccctcgtt    540
ctgctggcca agtggtacga gaagttcttt gggcgcctgt cccacctgaa cctgtgtgtt    600
accaatgcta tgcgagaaga cctggcggat aactggcaca tcagggctgt gaccgtctac    660
gacaagcccg catctttctt taaagagaca cctctggacc tgcagcaccg gctcttcatg    720
aagctgggca gcatgcactc tccgttcagg gcccgctcag aacctgagga cccagtcacg    780
gagcggtcgg ccttcacgga gcgggatgct gggagcgggc tggtgacgcg tctccgtgag    840
cggccagccc tgctggtcag cagcacgagc tggacagagg acgaagactt ctccatcctg    900
ctggcagctt tagaaaagtt tgaacaactg actcttgatg gacacaacct tccttctctc    960
gtctgtgtga taacaggcaa agggcctctg agggagtatt atagccgcct catccaccag   1020
aagcacttcc agcacatcca ggtctgcacc ccctggctgg aggccgagga ctaccccctg   1080
cttctagggt cggcggacct gggtgtctgt ctgcacacgt cctccagtgg cctggacctg   1140
cccatgaagg tggtggacat gtttgggtgc tgtttgcctg tgtgtgctgt gaacttcaag   1200
tgtttacatg agctggtgaa acatgaagaa aatggcctgg tctttgagga ctcagaggaa   1260
ctggcagctc agctgcagat gcttttctca aactttcctg atcctgcggg caagctaaac   1320
cagttccgga agaacctgcg ggagtcgcag cagctccgat gggatgagag ctgggtgcag   1380
actgtgctcc ctttggttat ggacacataa ctcctgggcc agaggctaaa accccrggac   1440
ccctgctgtc cttcccgcag cttcttctyg gagtctcagg gcaaaccctt tcgagcagcr   1500
cctcccagtg gccagaagct gaaatgacrg cagtggtrct gcctggtaaa agaattggtt   1560
ctgtgacccg ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagggcggcc gct          1613

<210> 915
<211> 1191
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1136)
<223> n equals a,t,g, or c

<400> 915
cacgcgtccg gccagagtga gtgtttacac cggcggcagt scggccgggt tccttccgcg     60
ggacgggtga gggcgctggg gccctgggca gcgcgggctc gatgtgtgtc agccaagtag    120
ctggtcccac tggagcggga gaaagagaga gcgcgaaaga gagaggatgt ctctctcaga    180
ctggcacctg gcggtgaagc tggctgacca gccacttact ccaaagtcta ttcttcggtt    240
gccagagaca gaactgggag aatactcgct agggggctat agtatttcat ttctgaagca    300
gcttattgct ggcaaactcc aggagtctgt tccagaccct gagctgattg atctgatcta    360
ctgtggtcgg aagctaaaag atgaccagac acttgacttc tatggcattc aacctgggtc    420
cactgtccat gttctgcgaa agtcctggcc tgaacctgat cagaaaccgg aacctgtgga    480
caaagtggct gccatgagag agttccgggt gttgcacact gccctgcaca gcagctcctc    540
ttacagggag gcggtcttta agatgctcag caataaggag tctctggatc agatcattgt    600
ggccacccca ggcctcagca gtgaccctat tgctcttggg gttctccagg acaaggacct    660
cttctctgtc ttcgctgatc ccaatatgct tgatacgttg gtgcctgctc acccagccct    720
cgtcaatgcc attgtcctgg ttctgcactc cgtagcaggc agtgccccaa tgcctgggac    780
tgactcctct tcccggagca tgccctccag ctcataccgg gatatgccag gtggcttcct    840
gtttgaaggg ctctcagatg atgaggatga ctttcaccca aacaccaggt ccacaccctc    900
tagcagtact cccagctccc gcccagcctc cctggggtac agtggagctg ctgggccccg    960
gcccatcacc cagagtgagc tggccaccgc cttggccctg gccagcactc cggagagcag   1020
ctctcacaca ccgactcctg gcacccaggg tcattcctca gggacctcac caatgtcctc   1080
tggtgtccag tcagggacgc ccatcaccaa tgatctcttc agccaagccc tacagnatgc   1140
ccttmaggcc tctgggmagc ccaagcttaa agccrtggca gccagttgca g            1191

<210> 916
<211> 1287
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (826)
<223> n equals a,t,g, or c

<400> 916
ccactgtacc ccaggccttt aataggcagg agccccactg cttccagcct ctggtgccaa     60
cacagttgcc aaacccattg agcttggggc tgccccgtgg aggcctcctg ggtatggacc    120
aggggcttgt tgagagctga gccatgcaca caggtgcaga caccccccaa ctcccatgca    180
cacggctagt ccaggcgcct ccacgctgca ccgtraggac tgcagggcat gtccccgtga    240
rggctatggg cctctktagg tgggcttcca aggtcctggg tgcagccggg tgcatggmag    300
cccttytggc gggggtgagc gcacgascaa agtcactgga agccgggttt ccggaagctc    360
gcagcttggc ctgcaccaca cgccctcccc ttttggcttc acgccatcag gcctcaagtg    420
ggcatggggg cagggacggg cccaggaact gttgttttct caggattctt tcagctggga    480
acatggcagg tgagcagagc ttggtgcctc tgccgtggcc cctgctgggg cagcccgtgt    540
tgccggagcc tctaagccaa agagcccgtt ggccgtggtt ggtgggggtg gacgtggggg    600
tgtcccacct ggaccagact ggcgtgggtg agctccacac cctgcctggc aatggtatga    660
gagtcggacc tggacagggc cagctgctgg gggagcggca ctggggactg gaggctggaa    720
gcgggtggtg tgtgtcccct gtttactttt agctgagctg gggttgggtg tacgggttct    780
gttcctctga gccctgcggc ccacctgatg tttamgtgtg tgtgtnargg ggggcggggg    840
tggcaggtgt ccccccctgg tccccgcccc aaragcctgc tgtctgtatg gaggaggtgc    900
takmccggtc caccggctgc tgcccacccc tgcatgcccc agttgcccac cccgcctgcc    960
cctggacatg aagtggtcac gcttcatcca cggctccttc ccacccctcg gcagtggctg   1020
tgcaatgttt taagttcaca agttcctgct cctccccaca ctgagctcct ttgttcctcc   1080
ccctccagcc tttgcctggg aactggtcct tgtttgccgg gcttctcgga gggttcactg   1140
tacattcgtt ctcaggtggt cttgtggctg tctttcggaa aatggttatt ttatatgatt   1200
tgtcatggaa tttgttctaa taaatcattc ttctatcaca tggcagcmcs ctggaaaaaa   1260
aaaaaaaaaa aaaaaaaaaa aaaaaaa                                       1287

<210> 917
<211> 772
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (685)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (770)
<223> n equals a,t,g, or c

<400> 917
ctacactata gccctcagaa ggacgacttt tttctctttt agcaagatgg cagttatagc     60
cagaggacag ctcaggttgg tgctttgctg ggatttagtt aatatgatga tgtatacata    120
ttttatattc agctctttac agtgaatgta aaacaaatgt aatttaaggg attagtaata    180
tatacttgta cagtcattat tgagtcttag ccatttatac tctgtcagag aaaatctgcc    240
tttgctgttc gtgtgtacct agaatgaaaa caattactta gaatgaaacc attttcttct    300
ccttttcaat aggttttatt tcgtctcaat ttcctggtag tggtgttatg tatagtaatg    360
gatcgacctt atcaattcta ttactttgtc cccttggtca ctgtatggtt catggtcata    420
tatgttactt tagcactatg gccacaaata atccaaaaaa aagcaaacgg aaattgtttc    480
tggcattttg gcttactgtt gaaactaggc tttttgctgt tattcatatg ttttttggca    540
tattctcagg gtgcatttga gaagatcttt tctctttggc cattgtccaa gtgttttgaa    600
ctgaaaggga atgtatatga atggtggttc agatggaggt tagaccgnta tgtaagtttt    660
ccacggaatg ctgtttgctt ttatntatct ggcttttgca gaaaccgcaa atactttctg    720
aaggaaaagg gtgaacctct ttttttcaaa caaaaatttc aaaattttcn gg            772

<210> 918
<211> 902
<212> DNA
<213> Homo sapiens

<400> 918
ggacggggat cctgatgctc tcaccccacc ctccgctgcc tctgcttctg ccaaggtggc     60
cgacactggg ccccctaccg accgtggcgt ccaggtgact gagcacgggg ccacagctgc    120
tcttgtccag tggccggatc agcggcctat cccgggcatc cgcatgtacc agatccagta    180
ccaacagctc ggctgatgac atcctcgtct acaggatgat cccggcggag agccgctcgt    240
tcctgctgac ggacctggcg tcaggccgga cctacgatct gtgcgtgctc gccgtgtatg    300
aggacakcgc cacggggctc acggccacgc gksctstgkg ctgcgcccgc ttctccaccg    360
aacctgcgct gcggccatgc ggggcgccgc acgctccctt cctgggcggc acgatgatca    420
tcgcgctggg cggcgtcatc gtagcctcgg tactggtctt catcttcgtg ctgctaatgc    480
gctacaaggt gcacggcggc cagccccccg gcaaggccaa gattcccgcg cctgttagca    540
gcgtttgctc ccagaccaac ggcgccctgg gccccacgcc cacgcccgcc ccgcccgccc    600
cggagcccgc ggcgctcagg gcccacaccg tggtccagct ggactgcgag ccctgggggc    660
ccggccacga acctgtggga ccctagccag gcgccccccc ctctaagggt cctctggccc    720
cacggacagc aggacccgga caccctgtgg gacctggcct caaactcacc aaatcgctca    780
tggtttttaa aactctgatg gggagggtgt cggggacacc ggggcaaaac aagaaagtcc    840
tatttttcca armttgggcg aaacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa    900
aa                                                                   902

<210> 919
<211> 1894
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1821)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1845)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1865)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1883)
<223> n equals a,t,g, or c

<400> 919
gcttggagaa gggcatgtgt ggggtgtgtg tgggatgtgg gttgtgtgta tatctggcat     60
gtgtcccagt cacttgcaga agggtgactt cttgccagcc gcatcgagat gccatgcatt    120
gggttcctag gttggactca tacccgaggg tggcagtggg aagattcggg tctcgtttct    180
ctctgtcagg actaccgtgg tttgttctgc agcctcctgg agacaaggcg tcccttcccg    240
ggwgctgtcg gtctrgatct ragggagctc tytgtgtggg ctctgctgcg ctgggagcct    300
gtcacggtag gagctctccc ggtaccagtg tccacagacc gcccaacaca gaggctttga    360
ggcttctcta gatcggaacc tctttggtga cattcccgac cagccctgca agagaaacga    420
caktgtgtgt gtgagcagag gtggcygcac acctgctgga catctttgcc aggctgtgcc    480
ttctcatgtt tcatagacag tggtctgtgc tggcagaggc tgctgcccct ggttggggct    540
atcaggagag tgggggatgg tggccacatg tccyccaggt ggtctcccgg tgcatagctg    600
gtggctctgg gcaagccatc ccttgcttct cggggctgac gccaccgttg tgtccgagcc    660
cgccctcccc tgcttcctca gcgggacccc ttcatctgtt ggccttacct gtcctcagaa    720
aggaagargt gaccccaccc agccacctct cccttttatg gaactcgaga gggtggccct    780
actgtgcacc ccttccttgt gagtagctct caactgtcct ggagagcaga ggctatttgg    840
ggtcggagga gccctcgata cctgcgaata catctgcttt ccaggctgct gtttattctg    900
agacgactgt gctgtagctt cccttgcagc tgcaataacc cgcaggtctt cactgaggtg    960
gaggctttgg ggtagaattc tccatttatt ttactactta atacaaaaca tttatttttg   1020
accagtcctg tggcttccat tagcaatatg tttcctttcc caaatatgca aatagtggct   1080
ttgtttgctc aattttgtga gtgctttgga atttaaatga ttgtataact caagaagatt   1140
acttttctat gttgctcaag ctgtgcctgc caacttgtaa cttaataaat acaggaaatc   1200
ctcagagaag gtgatatttt caggaaaaag acaaatgccc tcatagtagt gggaagtgtg   1260
aaggtgaccg tgaacatcct tcctcatcgg gtctgtcccc gtcatttcct cccggagtcg   1320
tcgcaggtgg agatggacaa cgtggtgttg gacttagacc tccttcagtg tggctctgct   1380
gggccagagg catcctgctg tcccgggtgg ctgcctcgct gtctgcaccc cctctccctg   1440
gggcagcttt gcttcctgcc cctgtgctcg gggcctgggt ggttactggc gtgtagatgg   1500
aattgctttt ttaatatggg aagatacatt tatttttttc catgtgggtg ggtgtctctt   1560
tttggatttt cttctgtttt tacgtttctc ttcttagaag ggtgggagag aatcaagctc   1620
ctgtggccac ctgtgtccca gcagcaagtg aagtggagct gctcagggtg ccctctcctg   1680
cggaccaagt ctcygaatgt tcaaagatga rgggcctggc ttccgtgctc tggcttttgt   1740
aacttatctg gaagggaaaa gcacatgcct tcaacgggca aggtatggtc ccttttcttc   1800
tcggggggtt gaacttgcaa nttctggggt gaaactggtc ccttntggca ttggtttacc   1860
cgggngaagg ttctggaagt ttnaaaaatg gtaa                               1894

<210> 920
<211> 2092
<212> DNA
<213> Homo sapiens

<400> 920
gagggtttga agccgcgccg cgagggagcg aggtcgcagt gacagcggcg ggcgatcgga     60
cccaggctgc cccgccgtac ccgcctgcgt cccgcgctcc cgccccagca tgacagcccc    120
ggcgggtccg cgcggctcag agaccgagcg gcttctgacc cccaaccccg ggtatgggac    180
ccaggcgggg ccttcaccgg cccctccgac acccccagaa gaggaagacc ttcgccgtcg    240
tctcaaatac tttttcatga gtccctgcga caagtttcga gccaagggcc gcaagcctgc    300
aagctgatgc tgcaatggtc aagatcctgg tggtcacggt gcagctcatc ctgtttgggc    360
tcagtaatca gctggctgtg acattccggg aagagaacac catcgccttc cgacacctct    420
tcctgctggg ctactcggac ggagcggatg acaccttcgc agcctacacg cgggagcagc    480
tgtaccaggc catcttccat gctgtggacc agtacctggc gttgcctgac gtgtcactgg    540
gccggtatgc gtatgtccgt ggtgggggtg acccttggac caatggctca gggcttgctc    600
tctgccagcg gtactaccac cgaggccacg tggacccggc caacgacaca tttgacattg    660
atccgatggt ggttactgac tgcatccagg tggatccccc cgagcggccc cctccgcccc    720
ccagcgacga tctcaccctc ttggaaagca gctccagtta caagaacctc acgctcaaat    780
tccacaagct ggtcaatgtc accatccact tccggctgaa gaccattaac ctccagagcc    840
tcatcaataa tgagatcccg gactgctata ccttcagcgt cctgatcacg tttgacaaca    900
aagcacacag tgggcggatc cccatcagcc tggagaccca ggcccacatc caggagtgta    960
agcaccccag tgtcttccag cacggagaca acagcttccg gctcctgttt gacgtggtgg   1020
tcatcctcac ctgctccctg tccttcctcc tctgcgcccg ctcactcctt cgmggcttcc   1080
tgctgcagaa cgagtttgtg gggttcatgt ggcggcagcg gggacgggtc atcagcctgt   1140
gggagcggct ggaatttgtc aatggctggt acatcctgct cgtcaccagc gatgtgctca   1200
ccatctcggg caccatcatg aagatcggca tcgaggccaa gaacttggcg agctacgacg   1260
tctgcagcat cctcctgggc acctcgacgc tgctggtgtg ggtgggcgtg atccgctacc   1320
tgaccttctt ccacaactac aatatcctca tcgccacact gcgggtggcc ctgcccagcg   1380
tcatgcgctt ctgctgctgc gtggctgtca tctacctggg ctactgcttc tgtggctgga   1440
tcgtgctggg gccctatcat gtgaagttcc gctcactctc catggtgtct gagtgcctgt   1500
tctcgctcat caatggggac gacatgtttg tgacgttcgc cgccatgcag gcgcagcagg   1560
gccgcagcag cctggtgtgg ctcttctccc agctctacct ttactccttc atcagcctct   1620
tcatctacat ggtgctcagc ctcttcatcg cgctcatcac cggcgcctac gacaccatca   1680
agcatcccgg cggcgcaggc gcagaggaga gcgagctgca ggcctacatc gcacagtgcc   1740
aggacagccc cacctccggc aagttccgcc gcgggagcgg ctcggcctgc agccttctct   1800
gctgctgcgg aagggacccc tcggaggagc attcgctgct ggtgaattga ttcgacctga   1860
ctgccgttgg accgtaggcc ctggactgca gagacccccg cccccgaccc cgcttattta   1920
tttgtagggt ttgcttttaa ggatcggctc cctgtcgcgc ccgaggaggg cctggacctt   1980
tcgtgtcgga cccttggggg cggggagact gggtggggag ggtgttgaat aaaagggaaa   2040
ataaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaccty ggggggggcc cc           2092

<210> 921
<211> 2744
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2699)
<223> n equals a,t,g, or c

<400> 921
acacactgat agcttatagt gatttaggat actacattat caataaactg caccatgtgg     60
acgagtcggt ggggagcaag acgagaaggg ccttcctgta cctcgccgcc tttcctttca    120
tggacgcaat ggcatggacc catgctggca ttctcttaaa acacaaatac agtttcctgg    180
tgggatgtgc ctcaatctca gatgtcatag ctcaggttgt ttttgtagcc attttgcttc    240
acagtcacct ggaatgccgg gagcccctgc tcatcccgat cctctccttg tacatgggcg    300
cacttgtgcg ctgcaccacc ctgtgcctgg gctactacaa gaacattcac gacatcatcc    360
ctgacagaag tggcccggag ctggggggag atgcaacaat aagaaagatg ctgagcttct    420
ggtggccttt ggctctaatt ctggccacac agagaatcag tcggcctatt gtcaacctct    480
ttgtttcccg ggaccttggt ggcagttctg cagccacaga ggcagtggcg attttgacag    540
ccacataccc tgtggtcaca tgccatacgg ctggttgacg gaaatccgtg ctgtgtatcc    600
tgctttcgac aagaataacc ccagcaacaa actggtgagc acgagcaaca cagtcacggc    660
agcccacatc aagaagttca ccttcgtctg catggctctg tcactcacgc tctgtttcgt    720
gatgttttgg acacccaacg tgtctgagaa aatcttgata gacatcatcg gagtggactt    780
tgcctttgca gaactctgtg ttgttccttt gcggatcttc tccttcttcc cagttccagt    840
cacagtgagg gcgcatctca ccgggtggct gatgacactg aagaaaacct tcgtccttgc    900
ccccagctct gtgctgcgga tcatcgtcct catcgccagc ctcgtggtcc taccctacct    960
gggggtgcac ggtgcgaccc tgggcgtggg ctccctcctg gcgggctttg tgggagaatc   1020
caccatggtc gccatcgctg cgtgctatgt ctaccggaag cagaaaaaga agatggagaa   1080
tgagtcggcc acggaggggg aagactctgc catgacagac atgcctccga cagaggaggt   1140
gacagacatc gtggaaatga gagaggagaa tgaataaggc acgggacgcc atgggcactg   1200
cagggacagt cagtcaggat gacacttcgg catcatctct tccctctccc atcgtatttt   1260
gttccctttt ttttgttttg ttttggtaat gaaagaggcc ttgatttaaa ggtttcgtgt   1320
caattctcta gcatactggg tatgctcaca ctgacggggg gacctagtga atggtcttta   1380
ctgttgctat gtaaaaacaa acgaaacaac tgacttcata cccctgcctc acgaaaaccc   1440
aaaagacaca gctgcctcac ggttgacgtt gtgtcctcct cccctggaca atctcctctt   1500
ggaaccaaag gactgcagct gtgccatcgc gcctcggtca ccctgcacag caggccacag   1560
actctcctgt cccccttcat cgctcttaag aatcaacagg ttaaaactcg gcttcctttg   1620
atttgcttcc cagtcacatg gccgtacaaa gagatggagc cccggtggcc tcttaaattt   1680
cccttccgcc acggagttcg aaaccatcta ctccacacat gcaggaggcg ggtggcacgc   1740
tgcagcccgg agtccccgtt cacactgagg aacggagacc tgtgaccaca gcaggctgac   1800
agatggacag aatctcccgt agaaaggttt ggtttgaaat gccccggggg cagcaaactg   1860
acatggttga atgatagcat ttcactctgc gttctcctag atctgagcaa gctgtcagtt   1920
ctcaccccca ccgtgtatat acatgagcta acttttttaa attgtcacaa aagcgcatct   1980
ccagattcca gaccctgccg catgactttt cctgaaggct tgcttttccc tcgcctttcc   2040
tgaaggtcgc attagagcga gtcacatgga gcatcctaac tttgcatttt agtttttaca   2100
gtgaactgaa gctttaagtc tcatccagca ttctaatgcc aggttgctgt agggtaactt   2160
ttgaagtaga tatattacct ggttctgcta tccttagtca taactctgcg gtacaggtaa   2220
ttgagaatgt actacggtac ttccctccca caccatacga taaagcaaga cattttataa   2280
cgataccaga gtcactatgt ggtcctccct gaaataacgc attcgaaatc catgcagtgc   2340
agtatatttt tctaagtttt ggaaagcagg ttttttcctt taaaaaaatt atagacacgg   2400
ttcactaaat tgatttagtc agaattccta gactgaaaga acctaaacaa aaaaatattt   2460
taaagatata aatatatgct gtatatgtta tgtaatttat tttaggctat aatacatttc   2520
ctattttcgc attttcaata aaatgtctct aatacaatac ggtgattgct tgtgtgctca   2580
acatacctgc agttgaaacg tattgtatca atgaacattg taccttattg gcagcagttt   2640
tataaagtcc gtcatttgca tttgaatgta aggctcagta aatgacagaa ctatttttnc   2700
attatgggta actgggggaa taaatggggt cactgggagt aggg                    2744

<210> 922
<211> 2946
<212> DNA
<213> Homo sapiens

<400> 922
cgcggacggg tgagaggccg cggcggcagg tccacctggg cttgcgaagg cacagattcc     60
ccgtccacag ctcacgacca gatgcaccag caggagtcca catcgaggac gtcctccggg    120
cactcccacg accagtgacc aggagttaaa ctttgggatg tgcccgtgat gttggaccac    180
aaggacttag aggccgaaat ccaccccttg aaaaatgaag aaagaaaatc gcaggaaaat    240
ctgggaaatc catcaaaaaa tgaggataay gtgaaaagcg cgcctccaca gtcccggctc    300
tcccggtgcc gagcggcggc gttttttctt tcattgtttc tctgcctttt tgtggtgttc    360
gtcgtctcat tcgtcatccc gtgtccagac cggccggcgt cacagcgaat gtggaggata    420
gactacagtg ccgctgttat ctatgacttt ctggctgtgg atgatataaa cggggacagg    480
atccaagatg ttctttttct ttataaaaac accaacagca gcaacaattt cagccgatcc    540
tgtgtggacg aaggcttttc ctctccctgc acctttgcag ctgctgtgtc gggggccaac    600
gssagcacgc tctgggagwg acctgtggcc caagacgtgg ccctcgtgga gtgtgctgtg    660
ccccagccaa gaggcagtga ggcaccttct gcctgcatcc tggtgggcag acccagttct    720
ttcattgcag tcaacttgtt cacaggggaa accctgtgga accacagcag cagcttcagc    780
gggaatgcgt ccatcctgag ccctctgctg caggtgcctg atgtggacgg cgatggggcc    840
ccagacctgc tggttctcac ccaggagcgg gaggaggtta gtggccacct ctactccggc    900
agcaccgggc accarattgg cctcagaggc agccttggtg tggacgggga aagtggcttc    960
ctccttcacg tcaccaggac aggtgcccac tacatcctct ttccctgcgc aagctccctc   1020
tgcggctgct ctgtgaaggg tctctacgag aaggtgaccg ggagcggcgg cccgttcaag   1080
agtgacccgc actgggagag catgctcaat gccaccaccc gcaggatgct ttcccacagc   1140
tctggagcag tgcgctacct gatgcatgtc ccagggaacg ccggtgcaga tgtgcttctt   1200
gtgggctcag aggccttcgt gctgctggac gggcaggagc tgacgcctcg ctggacaccc   1260
aaggcagccc atgtcctgag aaaacccatc ttcggccgct acaaaccaga caccttggct   1320
gtagccgttg aaaacggaac tggcaccgac agacagatcc tgtttctgga ccttggcact   1380
ggagccgtcc tgtgtagcct agccctcccg agcctccctg ggggtccact gtccgccagc   1440
ctgccgaccg cagaccaccg ctcagccttc ttcttctggg gcctccacga gctggggagc   1500
accagcgaga cggagaccgg ggaggcccgg cacagcctgt acatgttcca ccccaccctg   1560
ccgcgcgtgc tgctggagct ggccaatgtc tctacccaca ttgtcgcctt tgacgccgtc   1620
ctgtttgagc caagccgcca cgccgcctac atccttctga caggcccggc agactcagag   1680
gcacccggcc tggtctctgt gatcaagcac aaggtgcggg accttgtccc aagcagcagg   1740
gtggtccgcc tgggtgaggg tgggccagac agtgaccaag ccatcaggga ccggttctcc   1800
cggctgcggt accagagtga ggcgtagagg cacgccagcc agagcctgtg gagagactcc   1860
gcctgctgac actaaacgtc ctgggaagtg ggcccttccc tgggtctctg cactgactcc   1920
cccactcctg accctggtga tggtcgccac tgggcagcag cagccttacc agtcctccat   1980
gatcacaccc agggacctgc atgggtgagg ggacaccctg ggcctctctc ccgcccagca   2040
tcctccctga gtccccacac agggcctcac tctgcacccc accagggtcc cgctcacacc   2100
aggcagcctt catagtggtc tccctggcca ccttgggcag agctgggtca tgcagcaccc   2160
catccttacc cggtgccctc tccttgccag cttctcccca ggccagagcg gccatcgcgt   2220
agaaagaacc agggtgtccc cgggacaggc cgtcccccac cccatcctgt agaagtccat   2280
tccccttttc cctcctgtgc tctgtccccc aaggagtcat ggaactcagg gtactgggcc   2340
tcaacgggaa cctgagacag ctccagcttc gcagcccttc ccggagctac agggggatcc   2400
tctagcatgg ggggtgtgac ttggttcctt tgaccaggtc ctgtgaggaa gcctggagca   2460
agggtctccc ccagcaggat gggtggggcc tgctctggag ctgagcccgt ggccgctcac   2520
aggtgtcctt agtggtgttg cagctgtcta ctggctgcat gtgctgtgaa tatcccaagg   2580
aactggctgt ggaatgcgtg tttgggtcag tctgtgccct ctcagtagac actggagctg   2640
ctctgtccct gaagaggccc cgtgccccag gcatggcaag cgcctgcctc tccccttccg   2700
gtgctcacac gcccacgccg tgccacccga tgcaggactc acctctgtgc cttgctgctc   2760
ctgaggccca agggcagcca tggtgctctg tactgctcgg gccgcccagg tcacagagcc   2820
tgagcttcgt agccaaagca gcctgatgac ccacccacca aggaagaaag cagaataaac   2880
atttttgcac tgcctgaaaa accccggtgg tcaggcgtga gcctaaaaaa aaaaaaaaaa   2940
aaaaaa                                                              2946

<210> 923
<211> 2059
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (115)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (750)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (756)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (759)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1576)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1578)
<223> n equals a,t,g, or c

<400> 923
ggccttttca ctggctgaga gggtaaaacc tgtttcccag cctggtggca tcctgtggaa     60
agttggtcag ctgcaacctg gggtgtgaag gactggacct ggaagccctc ttgcntcgga    120
ggtgttgaaa ccaaaacgaa cgttatgtat aaaaccccag ctccatcgtg cgtgtcaggc    180
atctgctcag actgtcactg gcaagctcgt ttccrcgtca ycacaatgga gttgcttctg    240
ccaccctttg gcatcccttt aaagtgcccc ctacttctac tccccatgta agaggctttg    300
tgccttgcta aggagcaaag ggtagaaaca tgttgatttt aaagaagttt ttttaagaca    360
attgttgaca atagtaaaag agatcaggag gatcaagaat ctaaaacaag cctgaaggat    420
gtccaactgt gtatttagaa tttccgacat tcttctctac tggatctaca cattggaccc    480
catctgatcc tttgctgctt ttttggcttg gtcaggtcct ggcctcattt tggcgttacc    540
tgtgtcagag ttcaaggtgg atgtgcttag agctggtcag ccccttccag acctggacac    600
gtctgtggct ccttttcttt cttscttttt tttttttttt ttaaaaaaaa aaaaggttca    660
gcagaaatca gcgtggctag ttcacaaaga atttccagta tcagggaaaa actgtgcgtg    720
tgtgtgtgtg tgtgtgcgca cgtgtgtgtn gttgcngtng tgtgatacct ataaaacagt    780
ttctccttct ctgaagggaa aggaaagtgc taggcagcct gtgattagca acattctttg    840
tgcttttttg ttgttcctct gctctgtcac agttctacgt tgtttgcctt agaaatgtaa    900
tttttaaaaa ccattttaaa aatgaacggt gatttggctg gctggaaaaa atcacactgt    960
caggggacta tatttgaagt cagtctagac ggggctggac taggaaccca cctggaccca   1020
ggagacccca caggacccag gaggtccctg ccggaagcag aggttcaggt gagagtggct   1080
cacctctgag ctggtgaagt gaggacttgc ctgtgacatg acccagggat ctgctgctgg   1140
cttctggaga cagggccttg ggctgacttc tcaggttgat tgaggcctcc tgactagcgg   1200
tgttcccagg mtagaggtga ttggctgcaa caaagatgct tctattagtc tattagcagt   1260
gccttcggga ccctgggatt ttgctctctc tagaaaggtg ttttttattt ttttattttt   1320
tatctccccc ttttttcctg gctttgctcc agggtttgtg tatttgcctg tttattgtcc   1380
tgctcttttt ttttttggat gaaaactcca gcctttcctg actcacctcc atcttcggtt   1440
cttcagtttt ctgagaagag ttgggatatg tgggaagggg catgggagct cggcagcctc   1500
cgcctgccag gaaggcagtt tcgcctctgc aggaaagagc agagcccgtg ggaagccctg   1560
ggtgagggtg gcgcancngg cccagcacgc atggtattgc cagccacggg gggcctgcgt   1620
gtagtctctg ctccctgcat ttcaccttct ttgttgactt tccttctctg ttttccccca   1680
tctgtttgcc agaggggtgg gactggcaac agaacagccg tggctgcttt atctctcctc   1740
tccacggtgt actcaggcct gagtggtgac tcacgggagc ctggccacct cgcagctgtt   1800
cgccccctca acctttgaac tggaactgct ggctcacaca gggttttcga caactgcagc   1860
tgaatctcat ggaaaagctg gattcctctg ccttacgcag aaacacccgg gctccatctg   1920
ccaggtgctt gccactggtc ctggcagaaa tggcggctgc tgaaagtgac cttccaaatc   1980
cttggtggca cttcagcgcc acaggctctc caataaaaac cctttacaca caaaaaaaaa   2040
aaaaaaaaaa aaaaaaaaa                                                2059

<210> 924
<211> 1867
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1847)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1852)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1856)
<223> n equals a,t,g, or c

<400> 924
ggctttgctc cggtctggac ttcgtccctc ccagatctct gagctagcaa gcactgcagc     60
ccgagccaat tgcgaaagac caacaaagcc cagcccagcg gaaggaacgg tttcggagtt    120
gtttttcttt gatacgggag ttcctccttg ctctcgcccc tactctttct ggtgttagat    180
cgagcwaccc tctaaaagca gtttagagtg gtaaaaaaaa aaaaaaacac accaaacgct    240
cgcagccaca aaagggatga aatttcttct ggacatcctc ctgcttctcc cgttactgat    300
cgtctgctcc ctagagtcct tcgtgaagct ttttattcct aagaggagaa aatcagtcac    360
cggcgaaatc gtgctgatta caggagctgg gcatggaatt gggagactga ctgcctatga    420
atttgctaaa cttaaaagca agctggttct ctgggatata aataagcatg gactggagga    480
aacagctgcc aaatgcaagg gactgggtgc caaggttcat acctttgtgg tagactgcag    540
caaccgagaa gatatttaca gctctgcaaa gaaggtgaag gcagaaattg gagatgttag    600
tattttagta aataatgctg gtgtagtcta tacatcagat ttgtttgcta cacaagatcc    660
tcagattgaa aagacttttg aagttaatgt acttgcacat ttctggacta caaaggcatt    720
tcttcctgca atgacgaaga ataaccatgg ccatattgtc actgtggctt cggcagctgg    780
acatgtctcg gtccccttct tactggctta ctgttcaagc aagtttgctg ctgttggatt    840
tcataaaact ttgacagatg aactggctgc cttacaaata actggagtca aaacaacatg    900
tctgtgtcct aatttcgtaa acactggctt catcaaaaat ccaagtacaa gtttgggacc    960
cactctggaa cctgaggaag tggtaaacag gctgatgcat gggattctga ctgagcagaa   1020
gatgattttt attccatctt ctatagcttt tttaacaaca ttggaaagga tccttcctga   1080
gcgtttcctg gcagttttaa aacgaaaaat cagtgttaag tttgatgcag ttattggata   1140
taaaatgaaa gcgcaataag cacctagttt tctgaaaact gatttaccag gtttaggttg   1200
atgtcatcta atagtgccag aattttaatg tttgaacttc tgttttttct aattatcccc   1260
atttcttcaa tatcattttt gaggctttgg cagtcttcat ttactaccac ttgttcttta   1320
gccaaaagct gattacatat gatataaaca gagaaatacc tttagaggtg actttaagga   1380
aaatgaagaa aaagaaccaa aatgacttta ttaaaataat ttccaagatt atttgtggct   1440
cacctgaagg ctttgcaaaa tttgtaccat aaccgtttat ttaacatata tttttatttt   1500
tgattgcact taaattttgt ataatttgtg tttctttttc tgttctacat aaaatcagaa   1560
acttcaagct ctctaaataa aatgaaggac tatatctagt ggtatttcac aatgaatatc   1620
atgaactctc aatgggtagg tttcatccta cccattgcca ctctgtttcc tgagagatac   1680
ctcacattcc aatgccaaac atttctgcac agggaagcta gaggtggata cacgtgttgc   1740
aagtataaaa gcatcactgg gatttaagga gaattgagag aatgtaccca caaatggcag   1800
caataataaa tggatcacac ttaaaaaaaa aaaaaggggg ggccgcnctg gngggnccaa   1860
gctttcg                                                             1867

<210> 925
<211> 1176
<212> DNA
<213> Homo sapiens

<400> 925
aattcggcac gcgtccgtac agtcatggct gccgccgtcg ctgctgccgg tgcaggggaa     60
ccccagtccc cggacgaatt gctcccgaaa ggcgacgcgg agaagcctga ggaggagctg    120
gaggaggacg acgatgagga gctagatgag accctgtcgg agagactatg gggcctgacg    180
gagatgtttc cggagagggt ccggtccgcg gccggagcca cttttgatct ttccctcttt    240
gtggctcaga aaatgtacag gttttccagg gcagccttgt ggattgggac cacttccttt    300
atgatcctgg ttcttcccgt tgtctttgag acggagaagt tgcaaatgga gcaacagcag    360
caactgcagc agcggcagat acttctagga cctaacacag ggctctcagg aggaatgcca    420
ggggctctac cctcacttcc tggaaagatc tagattgtta ttgctgtttg agctgtctca    480
gtgggataag tttgaaattc aagtgtttga actgctgata atttggattt tttttttttt    540
ttaactttgg cacattgatc tatctaaacc tggtggggag aattatcccc acattgtctc    600
atggaaagac tcaacttgca actgtgccct ccacactatc cttacttctg tctccactct    660
gataccagag tgcagccatg cagayggtta ttccagctct ggtcacccga ctcctttcac    720
caaattgctc ctaactggaa gatctcactt tccccttgtg gggtaggaac cgatgccagt    780
gggagggatg tgcccctgac cattaacgac tgtttttttt tttttttttt aaagaatgga    840
gttgttgggg crggacatgc acacaatgtg aaacagacaa aatgcattac acctgtagtg    900
taaagtggcc actatgaatc cctatgtatg agaggaggga ggcaggctgc agcttcagcc    960
acagaatggg gactatggaa gacagcagga gctcatttcc tctgcacatt ttggctgtta   1020
gacctgtgtg tgtgtttaaa aaaagagaag tcagtgctca ctttttgtat ttaaatatta   1080
aaaatgattc caactgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1140
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa                             1176

<210> 926
<211> 853
<212> DNA
<213> Homo sapiens

<400> 926
tctccggata actgtgctcc tgacatcctt ccttatggtt ttgggaactg gtctaagatg     60
catacctata tcagacttaa tccttaaaag aagattaatt catggaggac agatgttaaa    120
tggattggca ggtccaactg taatgaatgc agcaccattt ctctctacga cgtggttttc    180
tgcagatgaa agggccacag ccacagctat tgcatcaatg ctcagttatc ttgggggagc    240
atgtgcattt ttagttggac cacttgttgt tccagctccc aatgggacat cacctcttct    300
tgctgcagag agcagcaggg cgcatattaa agatcgcata gaggctgtgt tatatgcaga    360
atttggagtt gtctgcttaa tattttctgc aacactagct tatttcccac cccgacctcc    420
tcttcctccc agtgttgctg cagctagcca gcggctgagt tatcggagaa gcgtttgtag    480
attattaagc aattttcgat ttttgatgat tgctttagca tatgccatac cacttggtgt    540
atttgctggc tggtctggag ttctggactt aattttaaca ccagcgcatg tcagccaagt    600
agatgctggc tggattggat tttggtccat agttggaggc tgtgttgttg gaatagctat    660
ggcaaggttt gcagatttta tcaggggtat gctgaaacta attcttctcc tcctgttttc    720
gggagctaca ctgtcatcca cgtggttcac cctgacctgt ttgaacagca tcacacacct    780
acctttaacc acagtgacat tgtatgcctc ctgtattctc ctgggagtgt tcttgaatag    840
cagcgtgcct ata                                                       853

<210> 927
<211> 1162
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1080)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1114)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1158)
<223> n equals a,t,g, or c

<400> 927
gcgcagctcc gccggcgcct ggtcccagcg cccgcggcgc cgcgtccccg gcccaaccat     60
ggcgtcctcc gcggccggct gcgtggtgat cgttggcagt ggagtcattg ggcgaagctg    120
ggccatgctg tttgccagtg gaggcttcca ggtgaaactc tatgacattg agcaacagca    180
gataaggaac gccctggaaa acatcagaaa ggagatgaag ttgctggagc aggcaggttc    240
tctgaaaggc tccctgagtg tggaagagca gctgtcactc atcagtggtt gtcccaatat    300
ccaagaagca gtagagggyg ccatgcacat tcaggaatgt gttccagaag atctagaact    360
gaagaagaag atttttgctc agttagattc catcattgat gatcgagtga tcttaagcag    420
ttccacttct tgtctcatgc cttccaagtt gtttgctggc ttggtccatg tgaagcaatg    480
catcgtggct catcctgtga atccgccata ctacatcccg ctggttgagc tggtccccca    540
cccggagacg gcccctacga cagtggacag aacccacgcc ctgatgaaga agattggaca    600
gtgccccatg cgagtccaga aggaggtggc cggcttcgtt ctgaaccgcc tgcaatatgc    660
aatcatcagc gaggcctggc ggctagtgga ggaaggaatc gtgtctccta gtgacctgga    720
ccttgtcatg tcagaagggt tgggcatgcg gtatgcattc attggacccc tggaaaccat    780
gcatctcaat gcagaaggta tgttaagcta ctgcgacaga tacagcgaag gcataaaaca    840
tgtcctacag acttttggac ccattccaga gttttccagg gccactgctg agaaggttaa    900
ccaggacatg tgcatgaagg tccctgatga cccggagcac ttagctgcca ggaggcagtg    960
gagggacgag tgcctcatga gactcgccaa gttgaaragt caagtgcagm yaasctggar   1020
atttccacct tttcttttca gcttgattgc atttgactat attttacagc cagtgattgn   1080
agtttcatgg taatatgtgg caaaatattt ttgnaattat tttctaatcc ctttcttaag   1140
tactctgggg ccctgcantt at                                            1162

<210> 928
<211> 670
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<400> 928
ggggnncccc ccnttttttt tttttttttt tttttttttt tttttwtktg gaagaataca     60
gaaatatgtt taatacttag tatcaaacta aaaagtaata taaaattaca aaacttcttt    120
tttttcatgc acaggctttt tctggtaagg accgctggga ttgaacagaa gcttccggta    180
aataagggcc ccgtcggcaa gacagcatac tgctgtcaca agtgcaaaca cccctccacc    240
aactgtcaat gttgtggttt ctggtatcag tgccaacaca gatacgatga gcatgaatac    300
tgttgttacc agtgagttga taatatcaag caaaggccaa aataaccact tcattaatcg    360
atcaagtctg agtacatata aaagtatgaa aaataagata acggtgactt caaatccagt    420
gataacaata tatggttcag gggcttgtgc gatgataaaa aaggtcatag atgtcacagt    480
tagtgccagc cgcagcatct tcacgtggcc tttcacactg aagcagaagg ggcgatgttt    540
tattttcggc tgcacgttat ccatcgcgtc tgcagaccca gcagcagcac tttccctcaa    600
ctcttctcag ctggctgcct gagtaggttc tgcgaagcga tagcaacmgc caaccgcgga    660
gcaccgccct                                                           670

<210> 929
<211> 1033
<212> DNA
<213> Homo sapiens

<400> 929
tcgacccacg cgtccggcgg ctggtgagcg cccgctggag gctggagctt ccgggccctg     60
gaaaggggtc cccgcgcgcc ccgggtcgga ggcagacccc tgggtttggg ggacatgggc    120
atttggggcg cctgaaccca agacctctgg atgagctgcc ccgttcagac catggatcct    180
gaggtgacct tgctgctgca gtgccctggc gggggcctgc cccaggagca gatacaggcc    240
gagctgagcc ccgcccatga ccgtcgccca ctgccaggtg gggacgaggc catcactgcc    300
atctgggaga cccggctaaa ggcccaaccc tggctcttcg acgcccccaa gttccgcctg    360
cactcagcca ccctggcgcc tattggctct cgggggccac agctgctcct gcgcctgggc    420
cttacttcct accgagactt cctgggcacc aactggtcca gctcagctgc ctggctgcga    480
cagcagggtg ccaccgactg gggtgacacg caggcctatc tggcggaccc actgggggtg    540
ggcgctgcac tagccacagc cgatgacttc cttgtcttcc tgcgccgctc ccggcaggtg    600
gctgaggccc ctgggctggt ggacgtacct ggtgggcacc ctgagcctca ggtgaacctg    660
ccgctgctca ccctgagcca gcccctgctg ttgggcatcg cccgaaatga gaccagtgct    720
ggccgagcca gtgccgagtt ctatgtccag tgcagcctga cttctgagca ggtgaggaag    780
cactacctga gtgggggacc cgaggcccac gagtctacag gaatcttctt tgtggagaca    840
cagaacgtgc ggagattgcc cgagacggag atgtgggctg aactctgccc ctcggccaaa    900
ggcgccatca tcctctacaa ccgggttcag ggaagtccca ctggagcggc cctagggtcc    960
ccagccctac tcccgccgct ctgaaaataa taaacgactt tattcttgga aaaaaaaaaa   1020
aaaaaactcg aga                                                      1033

<210> 930
<211> 594
<212> DNA
<213> Homo sapiens

<400> 930
tggacaaatt tttctgcctg ggcgctggat ccactggcaa ataccattaa ttggcggaat     60
ctgctgtgct gctttttatg cctggttgac gggaatgcaa cctcctgcat tgcgtaccat    120
ggtggcgctt gctacgtggg gaatgcttaa gttaagtggg cgacagtgga gtggctggga    180
tgtatggata tgttgtctgg cggcaatttt gctgatggat cctgttgcca ttctctcgca    240
aagtttatgg ctctctgccg ctgcggtcgc ggcattgata ttttggtatc agtggtttcc    300
ctgtcctgag tggcaactgc cgccggtatt gcgtgcartt gtttccctca tccatctgca    360
actgggaatc acacttctgc ttatgcccgt gcaaatcgtc atatttyatg gcattagtct    420
gacctcgttt attgcaaatc tattagcaat tcccttggtg acatttatca cggttccgtt    480
gatcctcgcc gcgatggttg tgcatttaag cgggccgtta atcctggagc aagggttatg    540
gtttcttgcc gaccggtctt tggctttact tttctggggg ttaaagagtt tgcc          594

<210> 931
<211> 703
<212> DNA
<213> Homo sapiens

<400> 931
gtgtttccgg aagacgwggc ggctctcgcc tgggctgttt cccggcttca tttctcccga     60
ctcagcttcc caccctgggc tttccgaggt gctktcgccg ctgtccccac cactgcagcc    120
atgatctcct taacggacac gcagaaaatt ggaatgggat taacaggatt tggagtgttt    180
ttcctgttct ttggaatgat tctctttttt gacaaagcac tactggctat tggaaatgtt    240
ttatttgtag ccggcttggc ttttgtaatt ggtttagaaa gaacattcag attcttcttc    300
caaaaacata aaatgaaagc tacaggtttt tttctgggtg gtgtatttgt agtccttatt    360
ggttggcctt tgataggcat gatcttcgaa atttatggat tttttctctt gttcaggggc    420
ttctttcctg tcgttgttgg ctttattaga agagtgccag tccttggatc cctcctaaat    480
ttacctggaa ttagatcatt tgtagataaa gttggagaaa gcaacaatat ggtataacaa    540
caagtgaatt tgaagactca tttaaaatat tgtgttattt ataaagtcat ttgaagaata    600
ttcagcacaa aattaaatta catgaaatag cttgtaatgt tctttacagg agtttaaaac    660
gtataaaact cacttgtata ataaacagtt tttgagggat ttt                      703

<210> 932
<211> 2664
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (487)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2649)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2656)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2659)
<223> n equals a,t,g, or c

<400> 932
gcaaagactt ctggtactct gtggtcaacg gggtcatctt taactgcttg gccgtgcttg     60
ccctgtcatc ccacctgaga accatgctca ccgaccctgg ggcagtaccc aaaggaaacg    120
ctacgaaaga atacatggag agcttgcagc tgaagccygg ggaagtcatc tacaagtgcc    180
ccaagtgctg ctgtattaaa cccgagcgcg cccaccactg cagtatttgc aaaagatgta    240
ttcggaaaat ggatcatcac tgcccgtggg tgaacaattg tgtaggagaa aagaatcaaa    300
gattttttgt gctcttcact atgtatatag ctctgtcttc agtccatgct ctgatccttt    360
gtggatttca gttcatctcc tgtgtccgag ggcagtggac tgaatgcagt gatttttcac    420
ctccgataac tgtaatcctg ttgatcttcc tgtgccttga gggtcttctg tttttcactt    480
tcactgncag ttatgtttgg cacccaaatc cactccatat gcaacgacga gacggagatc    540
gagcgattga aaagtgagaa gcccacatgg gagcggaggc tgcgatggga agggatgaag    600
tccgtctttg gggggccccc ctcamtcctc tggatgaatc cctttgtggg cttccgattt    660
aggcgactgc ccacgagacc cagaaaaggt ggcccggagt tctcagtgtg aggcgtggct    720
catcagactg aaacttgctc acagacttcc agttatttat ttggggtctg aaggatatca    780
acagctcatc tgtgaccaac agggcaactg gaacctacac aaaccaattg cttgcagcaa    840
gcagagtttt atatatttat agtcacagat ggcagaggaa gaggctctca gtccccacct    900
gtacaacaac ggaaaggtgt gtggccacac gaagaagcca aacgccgtgg cctcctgcag    960
agctggggct tctgtggara atacttcggg ttattacatg ggttattcaa atcctgggtc   1020
ctgagctgct gtttccaatc atgaagaaaa acagtgaatc cagtgaacag ggattctcca   1080
agcagtcatt tcagggggct cctgctgacc ccgccactca gcagtgcact ccccggatca   1140
cagcagggcg tttacataga aagacgtttt ggtctcgatt agctccgatg ctttgcactg   1200
aagttgcaaa agatctgtgc actgaacagt gaaggtggct tccggcacac tccccgctgc   1260
cccggaagag acatcctttg accctctcag caagtctgtg tgtgtgcgtg tctgtgcgtg   1320
tgcgcgcgtg tgtgcatgtg tgtcaaaatt gccagtgttg tttaggcaat gtaacattta   1380
ccggctgtgt acagcaaaca agctattttt tagaaaccga cgtttcaggg aagaggggag   1440
agagccgcgg ggtcctgccc gtggttacta tgaatgtatt gctgttggag gacatctcga   1500
tccaaagaac agccgttcct gtgcggccct tcgttgccct cctgctttca ttttttaaag   1560
aaatcttgag tgcttgaggg ccttggaact gatttttttt ttttgttcca gccaaattag   1620
cagtgtataa atggcaccta ggtaagagca gagctgcggc tcggtgactt gatacttggg   1680
gcagcccgat gctgtgtgtg gggcagggga ggcatcctta ctggagaggc agggcccagc   1740
cattgggcac ctctgggaag gggaggggac catgaggcag ccagcccctg gcaggggcga   1800
ctgtgccacc gcaggcagcg ctccagtcgg gaatggccag gatggcgccc tcttgttgga   1860
gtttttggtt agcttttacg ttttcttctc cacccacggc acaggtgata aaataggatc   1920
cttggtgcgg agcttaaaat tatgccagaa agccaacagc tcccctcgtg gggccttgcc   1980
ttaaacttgc ctggtttgta cattttttgc cggacgcatc aagaagcaat ctgtgacaaa   2040
gtctgagggt cttcctttat gcttgccctc cacactaaga gaagttggcg tctccctcct   2100
gggaattgtt ttgcctttct gttcatctgt gaactgtttt ttgtttttaa ttactctgta   2160
ccccatccga atcagggctt ctaccactgc tgatgcaaaa ccacaaaggg acctacctga   2220
gccaccgtcc tagccaagcg agcaaacctg cagggggttt ggaagtggac ttggtcaccg   2280
cagaagcgtg tgcgccgttg ggggaagagc tgcgtcacag ccagagggac aaagtgtggg   2340
tgatcctgga gacgccagtt tccgagattg ttctgcatat tcatttgcac attgttgtct   2400
gggttggaca tgcgtgtggg cttcagtgtg aggcttttaa tatgtatatc ctgttatcaa   2460
taaaacaatt atccaagtgg ttgaatcctg tgagacttgg caagtgtgtg caaatcaagt   2520
atacttgact tttcaacctc ttctttcaat gtaactttta tatgaaataa agtaatcaat   2580
taacagttct caaaaaaaaa aaaaaaaaaa aaaaaaaacc ccgggggggg ggccccggga   2640
acccaattnc cccccnaang gggg                                          2664

<210> 933
<211> 2547
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (35)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (106)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (191)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1363)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2547)
<223> n equals a,t,g, or c

<400> 933
aacgacggcc cagtgaaatt gtaaatacga cctcnactat agggccgaaa ttggggtaac     60
cgggcccccc cccctccgac aggcccagca cgaacggctc cgttgnacca gtggggtaaa    120
atccaatgga tgaatttgtg acgttgttca tgttyatgcc aaagtctgat tccgttacac    180
agcaccgatt nccatgcaat tattcgtgcc ttgttccaga atccgcactt taatattggg    240
atacagctca ttaaatttac cgattgccag cggtaaaaaa taaaatactg cggtcggaat    300
acacgctaac gtcaccatac cacgatgata agcattcata tcacgaatat taaaaagcgt    360
ttcatcgaat ttctttatta attcccgcgc ctccgggagc aacctttttc ctgcttttgt    420
taacgtaacc ttgcgagttg tacgctcaaa tagttgaaca tgtaaatctt cctccatctt    480
ttttattctt cgcgttaatg caggttgcgt aatattgagt aatttagcgg cattgttaaa    540
cgaactggac tctgccagta tgacaaatgc cttcatactt gataattcat gcttcattat    600
tactccggaa aatggaagcg acgattttgg gtggctggcc gttaaaaatt ttaactgcat    660
ttagccaact taaattaatg aaaaaatgtt attaatcgtt gagctaaagt cattagagat    720
gctttgccct taatgtaacc atatcgcaat aagttatgtt tttaaattga gggcattatt    780
atgaaaaaaa taccctgcgt gatgatgcga ggtggaacct cgaggggcgc gttcctgtta    840
gcggaacatt tacccgaaga tcaaacgcag cgcgataaaa tattgatggc aattatgggt    900
tccggtaacg atctggaaat tgacggtatt ggcggcggta atccactgac cagtaaagtc    960
gccattatta gccgttccag cgatccgcgt gctgatgtcg attatctgtt tgcgcaggta   1020
atcgttcatg agcaacgtgt cgataccacg cctaactgcg gcaatatgct gtctggtgtt   1080
ggggcattcg ccattgaaaa tggtttgatt gcagcgactt cgccagttac tcgcgtacgt   1140
atccgcaacg tcaatacggg tacgttcatc gaagctgatg tgcaaacgcc aaatggtgtt   1200
gtcgagtacg agggtagcgc cagaattgac ggcgtaccgg gtactgccgc accggttgcg   1260
ctcactttcc tgaatgccgc tggaaccaaa accggaaaag ttttcccgac tgataatcag   1320
attgattatt ttgacgatgt cccggtgacc tgtatcgata tgncgatgcc agtcgtcatt   1380
attccggctg aatatctggg aaaaacaggt tatgaattac cggcggaact ggatgccgac   1440
aaagcattat tagcccgcat tgaatctatc cgtctacaag cgggtaaagc aatgggctta   1500
ggtgatgtca gtaatatggt tatccctaaa cctgtgctta tttctccagc gcagaaaggc   1560
ggggcaatta atgtgcgtta ttttatgccg cattcttgcc atcgcgcgct ggcgataacc   1620
ggtgctattg ctatttccag tagttgtgca ttggaaggca ccgtcacccg acaaatcgtc   1680
ccttctgtag gatacggcaa tatcaatatt gaacacccca gtggtgcgct cgacgttcat   1740
ttaagtaatg aaggtcagga tgccacgacg ttacgcgcat ctgttattcg gacgaccaga   1800
aaaatatttt ccggtgaagt ttatcttccc tgaaaaaatt cgttgtcagg ataaggacaa   1860
tcaataaagg acttctgtat gagtcataca gaaagaacag gattttaaat gaataagaaa   1920
tcgttatgga agctaattct gatattagcg atcccatgta ttattggttt tatgccagct   1980
ccggcaggat taagcgaact ggcgtgggtg ctttttggta tttacctggc ggccattgtg   2040
gggctggtta tcaagccttt cccggaacct gtcgtactgt taattgccgt tgctgcctca   2100
atggtggtgg tcggtaactt atccgacggt gcgtttaaaa ccaccgccgt attaagcggt   2160
tactcttcag gtaccacctg gctggtgttc tcggcgttta ccttaagcgc cgcatttgtg   2220
accaccggtt taggtaaacg tattgcctat ctgctgattg gtaaaatcgg taacaccacg   2280
ctgggtctgg gttacgttac ggtattcctc gatctggtac tggctccggc aacaccgtct   2340
aacaccgcgc gtgcgggcgg cattgtgtta ccgatcatca acagcgtggc ggtggctttg   2400
gggtccgaac cggaaaaaag tccgcgtcgt gtcggacatt acctgatgat gtccatttac   2460
atggtcacca aaaccaccag ctatatgttc tttaccgcaa tggcggggaa cawtctggcg   2520
cggcgggaar tgattatcgc caacgcn                                       2547

<210> 934
<211> 1098
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (907)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1074)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1084)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1093)
<223> n equals a,t,g, or c

<400> 934
gcagacggcg tgcggctagc agcccgcatc gtggacacac cctgcaatga gatgaacacc     60
gacaccttcc tcgaggagat taacaaagtt ggaaaggagc tggggatcat cccaaccatc    120
atccgggatg aggaactgaa gacgagagga tttggaggaa tctatggggt tggcaaagcc    180
gccctgcatc ccccagccct ggccgtcctc agccacaccc cagatggagc cacgcagacc    240
atcgcctggg tgggcaaagg catcgtctat gacactggag gcctcagcat caaagggaag    300
actaccatgc cggggatgaa gcgagactgc gggggtgctg cggccgtcct gggggccttc    360
agagccgcaa tcaagcaggg tttcaaagac aacctccacg ctgtgttctg cttggctgag    420
aactcggtgg ggcccaatgc gacaaggcca gatgacatcc acctgctgta ctcagggaag    480
acggtggaaa tcaacaacac ggatgccgag ggcaggctgg tgctggcaga tggcgtgtcc    540
tatgcttgca aggacctggg ggccgacatc atcctggaca tggccaccct gaccggggct    600
cagggcattg ccacagggaa gtaccacgcc gcggtgctca ccaacagcgc tgagtgggag    660
gccgcctgtg tgaaggcggg caggaagtgt ggggacctgg tgcacccgct ggtctactgc    720
cccgagctgc acttcagcga gttcacctca gctgtggcgg acatgaagaa ctcagtggcg    780
gaccgagaca acagccccag ctcctgtgct ggcctcttca tcgcctcaca catcggcttc    840
gactggcccg gagtctgggt ccacctggac attgctgcac cggtgcatgc tggtgagcga    900
gccacangct tcggtgtggc ccttctgctg gcgctcttcg gcccgtgcct yttgaggacc    960
cttctgcttg aacctgggtg tccccaactg ggctgtgaag gtggatgtcs aggaggggga   1020
cstggggaag ggacttccaa gaagacgcaa agctttgggg gtgaagccct tctnggcctt   1080
gggncccttg acnaaaac                                                 1098

<210> 935
<211> 1137
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1091)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1097)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1118)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1121)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1128)
<223> n equals a,t,g, or c

<400> 935
tcgacccacg cgtccgattt ggcgcctgcg cgctgagtgc gtgccgctcc gccgaccgaa     60
gaggctggac atgacaccag tggcatatca cggccatggg gtctcagcat tccgctgctg    120
ctcgcccctc ctcctgcagg cgaaacaaga agatgacagg gacggtttgc tggctgaacg    180
agagcaggaa gaagccattg ctcagttccc atatgtggaa ttcaccggga gagatwgcat    240
cacctgtctc acgtgccagg ggacaggcta cattccaaca gagcaagtaa atgagttggt    300
ggctttgatc ccacacagtg atcagagatt gcgccctcag cgaactaagc aatatgtcct    360
cctgtccatc ctgctttgtc tcctggcatc tggtttggtg gttttcttcc tgtttccgca    420
ttcagtcctt gtggatgatg acggcatcaa agtggtgaaa gtcacattta ataagcaaga    480
ctcccttgta attctcacca tcatggccac cctgaaaatc aggaactcca acttctacac    540
ggtggcagtg accagcctgt ccagccagat tcagtacatg aacacagtgg tgaattttac    600
cgggaaggcc gagatgggag gaccgttttc ctatgtgtac ttcttctgca cggtacctga    660
gatcctggtg cacaacatag tgatcttcat gcgaacttca gtgaagattt catacattgg    720
cctcatgacc cagagctcct tggagacaca tcactatgtg gattgtggag gaaattccac    780
agctatttaa caactgctat tggttcttcc acacagcgcc tgtagaagag agcacagcat    840
atgttcccaa ggcctgagtt ctggacctac ccccacgtgg tgtaagcaga ggaggaattg    900
gttcacttaa ctcccagcaa acatcctcct gccacktagg aggaaacacc tccctatggt    960
accawttatg kttctcagaa ccagcagaat caagtgccta gctggcccag caaatagttg   1020
gcactcaata aagattgcag aatttaatac agatcttttc rstgtcttag gcattataaa   1080
tggaaatcat nacgggntct agggtatcaa accatggnag ngaggganct aggaatg      1137

<210> 936
<211> 1997
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1326)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1485)
<223> n equals a,t,g, or c

<400> 936
gttctacatc cgcctctgcg ccggctgcca cccgcgctcc ctccgccgcc gccgccttgc     60
tgctgctcaa agctgctgcc gccccttggg ctaaaaggtt ttcaaatgga acattttgat    120
gcatcactta gtacctattt caaggcattg ctaggccctc gagatactag agtaaaagga    180
tggtttcttc tggacaatta tatacccaca tttatctgct ctgtcatata tttactaatt    240
gtatggctgg gaccaaaata catgaggaat aaacagccat tctcttgccg ggggatttta    300
gtggtgtata accttggact cacactgctg tctctgtata tgttctgtga gttagtaaca    360
ggagtatggg aaggcaaata caacttcttc tgtcagggca cacgcaccgc aggagaatca    420
gatatgaaga ttatccgtgt cctctggtgg tactacttct ccaaactcat agaatttatg    480
gacactttct tcttcatcct gcgcaagaac aaccaccaga tcacggtcct gcacgtctac    540
caccatgcct cgatgctgaa catctggtgg tttgtgatga actgggtccc ctgcggccac    600
tcttattttg gwgccacact taatagcttc atccacgtcc tcatgtactc ttactatggt    660
ttgtcgtcag tcccttccat gcgtccatac ctctggtgga agaagtacat cactcagggg    720
cagctgcttc agtttgtgct gacaatcatc cagaccagct gcggggtcat ctggccgtgc    780
acattccctc ttggttggtt gtatttccag attggataca tgatttccct gattgctctc    840
ttcacaaact tctacattca ggtaaatctc acccttctct gggacttgga atctggggcc    900
tttacsarca aaggccctca tctawttact taatgggcat skggagccct tgctgggtga    960
caggctctgg cctctaatgg agtcactatg acaagagcag cccctgcctc tggggggctc   1020
mcagctcact ggaagacact agaatcctgt tcwagagcct gggtgaggaa gtcttgggat   1080
tccctgggaa atkgaaaact gtgcagcagg accctatgtt gcttccctct gacctgcagc   1140
agagacgtga gaggtgattt caatcagaaa tctctcagtt cactaccctg aacgtcatgg   1200
ccaaatgaaa tttcagaaga gatttttatc acagtcctca gatatggaga tcygcttttt   1260
tgtcccagct ttcttataca ttcagtcttc aggtgtgagg attcggttca ttcctaagca   1320
tatgangtgg tgatgtaggt ctttgctcac agaaagatcc atttagggca gataatttcc   1380
agtggagcct gaccacgttg cagccactgc tgattctcct gccatgcgtc accccccaga   1440
tgacatgtgt cctgcctttg ttgccagtgc ctggtagcca taagnctgct gatctgggca   1500
aaacacggag gtcaggagca agggcagagg ctgcaagtcc cgaggctcag acatttgtcc   1560
tttcttcttc tgtgcccaca agcacctgtg tgtggcatgt tgagtttcag tggaagtcat   1620
atacttctgg gcttcatagt ttatggctgc actgtgggac atacaccagc tacaaggaag   1680
gtgaaaggat aggacccgat gaagctgaaa tcacatttat tctaactact tatagcagca   1740
tagcactttg ttcatgaagg ctgagatagt cgcygaggca gtgaggaact tttgaagacg   1800
aacaagggat gtgggtgtca agagagctgc tgccaggtgg gaaagaccaa tttggccaca   1860
taacccctgt catctgccat ccagatacta aaaggcaaag caaagtgtaa attgaatttt   1920
ctatgtgaca ttttaaatag tatttctgyt gcagcctgtg attcagttaa cttacctcag   1980
ctaagcctca aaaaaaa                                                  1997

<210> 937
<211> 864
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (854)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (861)
<223> n equals a,t,g, or c

<400> 937
ttacgcctgc aggtaccggt ccggaattcc cggggcatct cagagcgccg ggaggatcgc     60
aagctggatg agcttctagg caaggaccac acgcaggtgg tgagccttaa ggacaagcta    120
gaatttgccc cgaaagctgt gctgaacaga aaccgcccag agaagaatta atggaggaca    180
cagggcccta tggtcctact gtgggtggtg acttgtcctg ctaccatgtt gacagagccc    240
cagaacccac atctaattgg ctttgttgct tattctggcc cttcccacac cacacagcca    300
cacaaatact ggctgctcct tgatggccag gcagacccag cagcagccga ggggccagtg    360
aagaggaagg ccgcatctgt tgtgtggtgg ccacaagcac tcaggcatct gagtttactg    420
gtgcactgct gggaggagag ttatgagatg aacattggct gtcaatctct gtgggcaggc    480
ggtttggcct ctagtgggaa tggctgggat ttgggcgttg cctttaggag ggatacctgc    540
atgtctagtt ccagtctgca ctggaaagaa ttcaaatatg cacctggctc ccttcactat    600
tttgccctat cctttgtgct cattcttact gaaatctgtc ttgtcagctc aggaatggga    660
ttcccccagg aaggaaagca cttttctgtt ctgggaagcc cagactgttc actttggggc    720
agggacgaac atgtgcctcg tgaatttgct tgaaaacagt caccatcttc tacccccatc    780
actgtatagt gaaaaacctg attaaagtgg tatctgagaa ccataaaaaa aaaaaaaaaa    840
aaaaaaaaaa aaangggggg nccc                                           864

<210> 938
<211> 1703
<212> DNA
<213> Homo sapiens

<400> 938
ggcaaaaagc taccacctgc cagtctgaag caccgagatg acatggccgc ttaccaacaa     60
gaagagcaga tgcagcttcc ccgagctgat gccattcgtt cacgtctcat cgatactttc    120
tctctcattg agcatttgca aggcttgagc caagctgtgc cgcggcacac tatcagggag    180
ttacttgatc cttcccgcca gaagaaactt gtattgggag atcaacacca gstagtgcgk    240
ttctctataa agcctcagcg tatagaacag atttcacatg cccagaggct gttgagcagg    300
cttcatgtgc gctgcagtca gaggccacct ctttctttgt gggccggatg ggtccttgag    360
tgtcctctct tcaaaaactt catcatcttc ctggtctttt tgaatacgat catattgatg    420
gttgaaatag aattgctgga atccacaaat accaaactat ggccattgaa gctgaccttg    480
gaggtggcag cttggtttat cttgcttatt ttcatcctgg agatccttct taagtggcta    540
tccaactttt ctgttttctg gaagagtgcc tggaatgtct ttgactttgt tgttaccatg    600
ttgtccctgc ttcccgaggt tgtggtattg gtaggggtaa caggccaatc ggtgtggctt    660
cagcttctga ggatctgccg ggtgctgagg tctctcaaac tccttgcaca attccgtcaa    720
attcaaatta ttattttggt cctggtcagg gccctcaaga gcatgacctt cctcttgatg    780
ttgctgctca tcttcttcta catttttgct gtgactggtg tctacgtctt ctcagagtac    840
acccgttcac ctcgtcagga cctggagtac catgtgttct tctcggacct cccgaattcc    900
ctggtaacag tgttcattct cttcaccttg gatcattggt atgcactgct tcaggacgtc    960
tggaaggtgc ctgaagtcag tcgcatcttc agcagcatct atttcatcct ttggttgttg   1020
cttggctcca ttatctttcg aagtatcata gtagccatga tggttactaa ctttcagaat   1080
atcaggaaag agctgaatga ggagatggcg cgtcgggarg ttcagctcaa agctgacatg   1140
ttcaagcggc agatcatcca gaggagaaaa aacatgtcac atgaagcact gacgtcaagc   1200
catagcaaaa tagaggacag gtcgtttgga ctgggagact cttgtgcacg aaaatctgcc   1260
cgggctaatg gaaatggatc aggatgaccg tgtttggccc agagactcac tcttccgata   1320
ttttgagttg ctagaaaagc ttcagtataa cctagaggaa cgtaagaagt tacaagagtt   1380
tgcagtgcag gcactgatga acttggaaga caagtaaagc aatggatggc ttcacttcca   1440
cccttcctgc aacctctact gcctgattag agtcctaatt ttaccctctc cctccctgat   1500
gcataggtaa aggcccctct gtggagtaag gagatcttca gagctgttag tgtaactaat   1560
tgagaagtat tgtttccatt gcgtgttcca ctcatgttgc ttctcttgtg aaccattaac   1620
tttaattgga tattattttt acctgttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1680
aaaaaaaaaa aaaaaaaact cga                                           1703

<210> 939
<211> 1751
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1032)
<223> n equals a,t,g, or c

<400> 939
gtcacaagtg ctaaaatctg aagaaaggaa gagcagttca taaatgctta tcttcacatt     60
gttcattggg ctgccctaac ctcccctgct cccagagaat gccagatggc tttacaattg    120
aggtggttca aacacagaag gccctttttc cttttattaa ttgctcagct atgtgtacat    180
tggcccccac acctgccacc tgaccagcgc ggcttctgcc tccctcagca ctgccagccg    240
ggggttttct tagactcatc ccckgggcca ccttccgctc ctctccctcc ctctgcatta    300
acatccaggc caccctcatt actccttggc aacctagctt gggttggcct ccccagccag    360
ccttccagac tattctttct ctcccttgca gcctgtcttg cacaccactg tggccaggtc    420
agtctttctg agaataccat ttcctcacat catggccctg tttacaaagc agtttcccat    480
ttgcctatca catcagatca aatcagaact cttcggctct ggattgaagc cgacgccact    540
gttcctggca agcctcattg ccctccgatc ccggcgttgg cctccgtccc tgtcaggtct    600
tgtacgatgc tgctctctgc catcctgccg tctccagctc tgcctgcatg ttggtcctgc    660
attgctctcc acctcacaga ctcttattcc acggctctgg ccagtccaaa gcatacatgg    720
cccagttagt tcccttttac ttgaaatatt ccctgaggag cccccaggta tttttcctta    780
ctcactggag acttgtagtc agggccacac tgatgtcatt tgggaattat ttgcaaagtc    840
acagatctgg acttctctct ccagctaaat catgagttcc tcagctaaat cacgggccca    900
cagttctgca gcagctggta aacactttta gtcacggaag gaagcctttt tcggktctca    960
gctctgccaa ggaacttatt tcacgtacac aaaaccacaa accgtgagag gattgctgcc   1020
tgtatcctgt tncccctcat cttttttttt ctttgaaaag atggtaaagc tgattataag   1080
aatttaaata acgtggccct agaactacac tctgactctg atccgcgtgt cctgcccaca   1140
gcaccaggcc acgaagacag accatgtcgc tatcctcaca tttgcttgta acttaggagg   1200
cttgccagta aaatcgatac taacagtgga cgtacttctc tttgaataag tttattctat   1260
ttccttctcc cattttcttt atttgttgaa aagaatgatg ctgattgaga agccaaatat   1320
tgttaaccat tttccccgtc tggcacggtt cttttgcaca gcactggatt aggccagggg   1380
actggcctaa ccctgcaaat atcaggaaag gactcttcta gggaaagtcg tactaatttg   1440
aattgatcac tagaaataca tggtctccac ctaaaagatg ctttgtcact taaaaggctg   1500
agtagtcatc ataatgtaaa gaaacctcta ttgtcatgca accatttgca cccagacatt   1560
gtgcctggtt ggcacttaac attttatcac ttgattctca caccaccctt gcaatgtgat   1620
gaaaccaagg ctcctaggtg ctaagtgaca ttcccctagt cacgcagcct agtgctagtc   1680
acgcagccta gtggtagagc gaggattcaa acccagtttt tgttttcctt tgagctggag   1740
ctgcaagaaa a                                                        1751

<210> 940
<211> 1790
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1761)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1772)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1775)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1779)
<223> n equals a,t,g, or c

<400> 940
gcgnccgcgg catggtcttc ggaggggtgg tgccctacgt cccgcagtat cgggacattc     60
gcaggacgca gaacgccgac ggyttctcca cctacgtgtg cctggtgctg ctggtggcca    120
acattttgcg gatactcttc tggtttggaa ggcgctttga gtccccgctg ctgtggcaga    180
gcgccatcat gatcctgacc atgctgctga tgctgaagct gtgcaccgag gtccgtgtgg    240
ccaacgagct caacgccagg cgccgctcct ttacagactt cgacccccac cacttctggc    300
agtggagcag cttctcggac tacgtgcagt gcgtcctggc cttcacgggc gtggcgggct    360
acatcaccta cctgtccatt gactccgccc tgtttgtgga gaccctgggc ttcctggctg    420
tgctgaccga agccatgctg ggtgtgcccc agctttaccg caaccaccgc caccagtcca    480
cggagggcat gagcatcaag atggtgctca tgtggaccag tggtgacgcc ttcaagacgg    540
cctacttcct gctgaagggt gcccctctgc agttctccgt gtgcggcctg ctgcaggtgc    600
tggtggacct ggccatcctg gggcaggcct acgccttcgc ccgccacccc cagaagccgg    660
cgccccacgc cgtgcacccc actggcacca aggccctctg acagtgggga ggacgaggat    720
gtgggaccgc cagccgcggg cactggtggg ccctgacctc cccgcgggga gggtgggtgc    780
cgtggcccct gcaggtgtgg cagagatggg gcaygggcat tggggtctcc atcagcctct    840
gtggggtgtc tcagggtggg cagtgggggt ggggctggga cgctgtttgt gctcagcggg    900
gacagccagg gttgatctgg ccccgagggt tttggatgtt tttaggatga cataaaaagc    960
aagtgttttc cccatttcct cttatgaaac accgtctgag cccaaggtac acattgggcg   1020
gcctgcagga acctgctcca ggtggacaca cgggccagca gccgcgaacc ttgaagctgg   1080
ggtgaccgca gagaccctgt aaggcctgtg agcggascct cgaccccgtg acaccctggc   1140
cagacaccct gcttggactg gggtggcctc tgctacccag gggtctggca cgggggaggg   1200
ctggggcttt ctctgcctgg tacacacgga aaggcggctg tgcggacgca gggtcaccgt   1260
gctccgggtt ttctgacagt cggtgtttcc tgggcctttg gagtggctgc gaggcctgaa   1320
cgccttgtgg atccgctgtg tccagcccgg ctgagcatcg ccagggctag ctcatgctgc   1380
tcttgtcagc ctctggttct cctcgagtcc ttggggacgt ggcagatgcc agcgaccatc   1440
agacaacgtg gaggccctca tgggcaatgg ctgagggggc cgggctgagg ctgtgcacat   1500
gcagtctgca cgccactctt gggctctgct ggcggagatc cccttccttc tgggtgcaga   1560
ctgcacctcc ggatgcagtt ttgatgtcca tcttccagga gagagacggt ctcgggtcca   1620
gggagtggag ggggctgccc ctgccgtgca gktcctggcc gatggcgcct taccctsctg   1680
ccctgggctt ttggcctgaa gcaaattcct rartgggggg tactggggcc tgccgcatcc   1740
tgtcctgtcc actgcccggg ngggttttct gnaanaaang tggggggtcc              1790

<210> 941
<211> 1398
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1270)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1279)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1362)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1375)
<223> n equals a,t,g, or c

<400> 941
gggtcgagca tgtagcggct gctggcggcg gggctcccgg ggcgggccgg gcgggccgcg     60
ggagccgcac gcggcgatat ggaagaggag ggcaagaagg gcaagaagta tttaggtcag    120
ttaacgtcca taccaggata cctgaatccc tccagtagga ctgaaatcct gcatttcata    180
gacaatgcaa agagagccca ccagcttccg ggacacttga ctcaggagca cgatgctgtg    240
ctcagcctgt ctgcgtacaa cgtcaagctg gcctggaggg acggggagga tatcatcctc    300
agggtgccca tccatgacat cgccgccgtc tcctatgttc gggatgacgc tgcacacctg    360
gtggtcctga agacagccca ggacccaggg atctccccca gccagagtct gtgtgcggaa    420
agttccagag gcctcagtgc aggctccctg tcggagagtg cagttgggcc cgtggaggca    480
tgctgcctgg tcatcctggc tgcagagagc aaggtcgctg cggaggagct ttgctgtctg    540
ctaggccagg tcttccaggt tgtttacacg gagtccacca tcgactttct ggacagagcg    600
atatttgatg gggcctctac cccgacccac cacctgtccc tgcacagcga tgactcttct    660
acaaaagtgg acattaagga gacctacgag gtggaagcca gcactttctg cttccctgaa    720
tctgtggatg tgggtggtgc atcaccccac agcaagacca tcagtgagag cgagctgagc    780
gccagsgcca ctgagctgct gcaggactac atgctgacgc tgcgcaccaa gctgtcatca    840
caggagatcc agcagtttgc agcactgctg cacgagtacc gcaatggggc ctctatccac    900
gagttctgca tcaacctgcg gcagytctac ggggacagcc gcaagttcct gctgcttggt    960
ctgaggccct tcatccctga gaaggacagc cagcacttcg agaacttcct ggagaccatt   1020
ggcgtgaagg atggccgcgg catcatcact gacagctttg gcaggcaccg gcgggccctg   1080
agcaccacat ccagttccac caccaatggg aacagggcca cgggcagctc tgatgaccgg   1140
tcggcaccct cagaggggga tgagtgggac cgcatgatct cggacatcag cagcgacatt   1200
gaggcgctgg gctgcatcac cccacagcaa gaccatcagt gagagcgagc tgagcgccag   1260
cgccactgan ctgctgcang actacatgct gacgctgcgc accaagctgt catcacagga   1320
gatccagcag tttgcagcac tgctgcacga ataccgcaac angtcctcta ctgtnaaagg   1380
acaaggactg ccgaagga                                                 1398

<210> 942
<211> 1337
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1337)
<223> n equals a,t,g, or c

<400> 942
cttccggttc tccgggcagc tgccactgct gtagcttctg ccacctgcca cgaccgggcc     60
tctccctggc gtttggtcac ctctgcttca ttctccaccg cgcctatggt ccctcttgga    120
gccagcgtgg cgggcctggc ggctcccggg tggtgagaga gcggtccggg aacgatgaag    180
gcctcgcagt gctgctgctg tctcagccac ctcttggctt ccgtcctcct cctgctgttg    240
ctgcctgaac taagcgggcc cctggcagtc ctgctgcagg cagccgaggc cgcgccaggt    300
cttgggcctc ctgaccctag accacggaca ttaccgccgc tgccaccggg ccctacccct    360
gcccagcagc cgggccgtgg tctggctgaa gctgcggggc cgcggggctc cgagggaggc    420
aatggcagca accctgtggc cgggcttgag acggacgatc acggagggaa ggccggggaa    480
ggctcggtgg gtggcggcct tgctgtgagc cccaaccctg gcgacaagcc catgacccag    540
cgggccctga ccgtgttgat ggtggtgagc ggcgcggtgc tggtgtactt cgtggtcagg    600
acggtcagga tgagaagaag aaaccgaaag actaggagat atggagtttt ggacactaac    660
atagaaaata tggaattgac acctttagaa caggatgatg aggatgatga caacacgttg    720
tttgatgcca atcatcctcg aagataagaa tgtgcctttt gatgaaagaa ctttatcttt    780
ctacaatgaa gagtggaatt tctatgttta aggaataaga agccactata tcaatgttgg    840
gggggtattt aagttacata tattttaaca acctttaatt tgctgttgca ataaataccg    900
tatcctttta ttatatcttt atatgtatag aagtactctr ttaatgggct cagagatgtt    960
ggggataaag tatactgtaa taatttatct gtttgaaaat tactataaaa cggtgttttc   1020
tgatcggttt ttgtttcctg cttaccatat gattgtaaat tgttttatgt attaatcagt   1080
taatgctaat tatttttgct gatgtcatat gttaaagagc tataaattcc aacaaccaac   1140
tggtgtgtaa aaataattta aaatttcctt tactgaaagg tatttcccat ttttgtgggg   1200
aaaagaagcc aaatttatta ctttgtgttg gggtttttaa aatattaaga aatgtctaag   1260
ttattgtttg caaaacaata aatatgattt taaattctct taaaaaaaaa aaaaaaaacc   1320
ccgggggggg gcccggn                                                  1337

<210> 943
<211> 1020
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1016)
<223> n equals a,t,g, or c

<400> 943
ttttttctcc gcccctaaga ggtkgactcc gggctggagc tgtcctgggg gagcttgttt     60
gcggcasggc tgctgctgcc actgctgtgc tgggggcccg gtcgccaggc aaaaagccct    120
cccacgtttg aggggagtca tgagccgttt cctgaatgtg ttaagaagtt ggctggttat    180
ggtgtccatc atagccatgg ggaacacgct gcagagcttc cgagaccaca cttttctcta    240
tgaaaagctc tacactggca agccaaacct tgtgaatggc ctccaagctc ggacctttgg    300
gatctggacg ctgctctcat cagtgattcg ctgcctctgt gccattgaca ttcacaacaa    360
gacgctctat cacatcacac tctggacctt cctccttgcc ctggggcatt tcctctctga    420
gttgtttgtc tatggaactg cagctcccac gattggcgtc ctggcacccc tgatggtggc    480
aagtttctcc atcctgggta tgctggtcgg gctccggtat ctagaagtag aaccagtatc    540
cagacagaag aagagaaact gaggccagca ttatcacctc caggactttc tcgttttcca    600
ccttggccat cttcttcctt cgtcgtctct cctctttaat ttcttttcta ttccatcatc    660
tgccctttta ttcactttta gcctcttttt ttaattttta aaatttaaag atatgcatac    720
tgaaaagtat ataacatgta cgtacaattt aaagaataat tttaaagtga atactacgta    780
actccatcca agtcaagaaa ttgccagctt ctcggaagcc cactgtgtct ccttccccta    840
cctgcaacct cttccaggct cccttttcca gccttcccct ttttcccttt tattttcatg    900
ccttgatttg acttgtgtgg tgggaacatg tgaactatga aacttaaacc tgctgcccac    960
ccagagcagc tktgaccaag gstgcttmag gggttgccac graggtgggc tccctntctt   1020

<210> 944
<211> 1672
<212> DNA
<213> Homo sapiens

<400> 944
gaattcggca cgagtgaacc tgtggggcaa gggggtcttc cctgggcccc aagagtgcag     60
agatgcctgg gtccgcagcc tggcagggca gctgcagctt tccccaggga gcttccgccc    120
tgccaactct gagagggtgg ggctcctact tgttgctggc tcccactggt tctgtggagc    180
atgcagcacc agctgcacct cctcatatgc tggggcaagg gctctaagtc caacacatca    240
tgcctgggcc cagtgctaag ctgctccaac atgtggagtc tggctctgct ggtagtggct    300
ggctctatgg gggtagcata cagctctgtg gtgatgtacg ttttgctctg ggtgccgctc    360
ccamttcctt cccacttcct tccttcaggg gcccctgaag cacagcccac aacttgggcc    420
cagtccccac actccgtgtg caagtgtggc accamcttgg gcccagctaa acctcagggc    480
ccctctttgc ctamtcctcc atgcctgatc atgttgctgt cctgccgcag gcagctaggt    540
ctggccccat cawggtggct gccggggktg ggttcccatg gtggcgaact ccggggatgc    600
tcccaggggt gggctccagg gattgcccac ctcaatatct gcacctgatg acccttggtc    660
tgtccctgtt ccccactgca gctgacatca tggtastgat cacttcamac aggctgccgc    720
tgtcctcaca tacaatttat aatttaaatt agaaagaaac ataaataaac gacataagat    780
tttgaatata atctatgtaa gtaatttcaa aatatgtttt attatcttct ccatgctaga    840
gaacatttta ttagtttata ttttaactaa ttttaaaaac gtaaacataa aattacatgt    900
gttgtcaagc taactcaatc gatgtttgag ataaaaatta acctaagacc aaagtatatt    960
attttgattt ccttagagga aaagttatgc agtaattact tgaagagtaa ttctctctac   1020
mattagcatt gcagatgcat ccattatacc actaaagtac acttaataaa taatacttaa   1080
garryyacca gacaccatak ggaaaaataa aaataaaaag tcattttgaa aaaagtttag   1140
aaagtaaatc attcctagaa tgcttggaaa agtatgtgcc tgtgtgccag tatttctgat   1200
cctaagagtt atgaatatct tatgaatagt tatgaatatc actgatagtg aacctgagtg   1260
taaatgcttg ggcttgggkt gcagatggac tacagataca aatctaaagt agtgtwccta   1320
gtagcactgt aactcagtta agtacttact ttttcatgcc ctcagtattt ttatctgcaa   1380
aataggaata aaatagctaa tcatgttatc ataagggtta agttatgaga tataataact   1440
atgaagtact taatgggtaa aggaaaaaat aagcttagca gttgttgttg ttgttgttgt   1500
tgacgacctt atttcaccat atacacttgt tagtaactca aaggggttct ccaaagtgaa   1560
atatttaaaa aacgaatgag ataaattatt attttgttat tagaaaatat atttagcaat   1620
ttgtctcact ggatcataaa actaattgtg gtatgagaac atttataaaa ca           1672

<210> 945
<211> 2290
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (525)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2196)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2254)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2256)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2274)
<223> n equals a,t,g, or c

<400> 945
ggaggaatgg gaagcccgct aagagaacag aagtcaaaaa cagttgggtt ctagatggga     60
ggaggtgtgc gtgcacatgt atgtttgtgt ttcaggtctt ggaatctcag caggtcagtc    120
acattgcagt gtgtcgcttc acctgnctcc ctcttttaaa gattttcctt ccctctttcc    180
aactccctgg gtcctggatc ctccaacagt gtcagggtta gatgcctttt atgggccact    240
tgcattagtg tcctgataga ggcttaatca ctgctcagaa actgccttct gcccactgga    300
aagggaggca ggggaaatac atgattctaa ttaatggtcc aggcagagag gacactcaga    360
atttcaggac tgaagagtat acatgtgtgt gatggtaaat gggcaaaaat catcccttgg    420
cttctcatgc ataatgcatg ggcacacaga ctcaaaccct ctctcacaca catacacata    480
tacattgtta ttccacacac aaggcataat cccagtgtcc agtgncacat gcatacacgc    540
acacattccc ttcctaggcc actgtattgc tttcctaggg catcttctta taagacacca    600
gtcgtataag ggagcccacc ccactcatct gagcttatca accaattaca ttaggaaaga    660
ctgtatttcc tagtaaggtc acattcagta gtactgaggg ttgggacttc aacacagctt    720
tttgggggat cataattcaa cccatgacag ccactgagat tattatatct ccagagaata    780
aatgtgtgga gttaaaagga agatacatgt ggtacaaggg gtggtaaggc aagggtaaaa    840
ggggagggag gggattgaac tagacacaca cagacacatg agcaggactt tggggagtgt    900
gttttatatc tgtcagatgc ctagaacagc acctgaaata tgggactcaa tcattttagt    960
ccccttcttt ctataagtgt gtgtgtgygg atatgtgtgc tagatgttct tgctgtgtta   1020
ggaggtgata aacatttgtc catgttatat aggtggaaag ggtcagacta ctaaattgtg   1080
aagacatcat ctgtctgcat ttattgagaa tgtgaatatg aaacaagctg caagtattct   1140
ataaatgttc actgttatta gatattgtat gtctttgtgt ccttttattc atgaattctt   1200
gcacattatg aagaaagagt ccatgtggtc agtgtcttac ccggtgtagg gtaaatgcac   1260
ctgatagcaa taacttaagc acacctttat aatgacccta tatggcagat gctcctgaat   1320
gtgtgtttcg agctagaaaa tccgggagtg gccaatcgga gattcgtttc ttatctataa   1380
tagacatctg agcccctggc ccatcccatg aaacccaggc tgtagagagg attgaggcct   1440
taagttttgg gttaaatgac agttgccagg tgtcgctcat tagggaaagg ggttaagtga   1500
aaatgctgta taaactgcat gatgtttgca ggcagttgtg gttttcctgc ccagcctgcc   1560
accaccgggc catgcggata tgttgtccag cccaacacca caggaccatt tctgtatgta   1620
agacaattct atccagcccg ccacctctgg actccctccc ctgtatgtaa gccctcaata   1680
aaaccccacg tctcttttgc tggctctggg tctctttggc gtcttgaacc ttatgccttc   1740
cctattgaag ttaatagggg ttcagcacaa cactgggtcc caggcatgca gccttgtctt   1800
tttatgtttg tcctcatggg catcatgtgg gccacaggga tcttacccaa aatcatgcct   1860
agcaggaaga gatgcctctc tattgatatt ccagctgccc cacaagcagg tatgtgccta   1920
ctcattctct gacatgtgtc ctaggtttct tgactgtaam attccgctta ataaataatg   1980
tattgagcac ctgctatatc cagagctctg ctgggcactc tggaagatta gagtttgaag   2040
aacacacaat cgttgtcctc cagaagttca tggtccagta gggagagaag gtcacaaaca   2100
gccakaatct acaagatgag aggggctatw aaagagagct gagaagagtt tcagagccac   2160
tgagaagata ctcattttag tcttggtaac gggaancttt ctggagttgg tggcatttaa   2220
gatgaaccac aaatggagca ggaatttaat gaanangaaa ggaccaggac gtcnaataga   2280
ggacacagca                                                          2290

<210> 946
<211> 1651
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1607)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1630)
<223> n equals a,t,g, or c

<400> 946
aatttctctt cctctttctg gaataatttg ctactatatg aattggactt atgtcttcta     60
cttttttggt actattggaa tattttggtt tcttttgtgg atctggttag ttagtgacac    120
accacaaaaa cacaagagaa tttcccatta tgaaaaggaa tacattcttt catcattaag    180
aaatcagctt tcttcacaga aktcagtgcc gtgggtaccc attttaaaat ccctgccact    240
ttgggctatc gtagttgcac acttttctta caactggact ttttatactt tattgacatt    300
attgcctact tatatgaagg agatcctaag gttcaatgtt caagagaatg ggtttttatc    360
ttcattgcct tatttaggct cttggttatg tatgatcctg tctggtcaag ctgctgacaa    420
tttaagggca aaatggaatt tttcaacttt atgtgttcgc agaattttta gccttatagg    480
aatgattgga cctgcagtat tcctggtagc tgctggcttc attggctgtg attattcttt    540
ggccgttgct ttcctaacta tatcaacaac actgggaggc ttttgctctt ctggatttag    600
catcaaccat ctggatattg ctccttcgta tgctggtatc ctcctgggca tcacaaatac    660
atttgccact attccaggaa tggttgggcc cgtcattgct aaaagtctga cccctgataa    720
cactgttgga gaatggcaaa ccgtgttcta tattgctgct gctattaatg tttttggtgc    780
cattttcttt acactattcg ccaaaggtga agtacaaaac tgggctctca atgatcacca    840
tggacacaga cactgaagga accaataaat aatcctgcct ctattaatgt atttttattt    900
atcatgtaac ctcaaagtgc cttctgtatt gtgtaagcat tctatgtctt tttttaattg    960
tacttgtatt agatttttaa ggcctataat catgaaatat cactagttgc cagaataata   1020
aaatgaactg tgtttaatta tgaataatat gtaagctagg acttctactt taggttcaca   1080
tacctgcctg ctagtcgggc aacatgaagt aggacagttc tgttgatttt ttagggccat   1140
actaaaggga atgagctgaa acagacctcc tgataccttt gcttaattaa actagatgat   1200
aattctcagg tactgataaa cacctgttgt tgttcacttt sctcataaaa attgtcagct   1260
ctctctgaca cttagacctc aaactttagc atctctgtgg agctgccatc cactgtataa   1320
tttcgcctgg caactggact gaggggagtg tgcccaggca gctgccaagc actccctccc   1380
tggcttcagg gtcagagtgc ccagcgttta tcagaggcag catccaagcc cagagccagt   1440
gtcgactctt cggctggtgc ctttcctctg aggggctatc aatgtgtaga taaagccctg   1500
agtaggcaag agcagtgaga tccactgcta tggtcttgat acatcctcaa actttccctt   1560
cccagcacag aggaatattg gctggcatgc aacctgcaaa ngaaaantgc gaggggccgg   1620
gcacggtggn tcatgcctgt taatcccagc a                                  1651

<210> 947
<211> 556
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (540)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (549)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<400> 947
acgtctttgt ctggctgatg ttgttcagct atttctctgt tccggcggca ttacaacgcc     60
gcgtgctggt gtatggcgtg ctcggggcga ttgttctgcg taccatcatg atcttcactg    120
gcagctggct aatttcgcag ttcgactgga tcctgtatat cttcggtgcc ttcctgctgt    180
ttaccggcgt gaagatggcg ctcgcccatg aagatgaatc aggcattggc gacaagccgc    240
tggtgcgctg gctacscggt catttgcgca tramcgacac catcgacaac garcatttct    300
ttgtgcgtaa gaatggattg ctgtacgcca caccgctgat gctggtactg attctggtgg    360
aattgagcga cgtgattttc gccgtggata gcattccggc tatcttcgcc gtgaccactg    420
gacccgttca ttgtgctgac ctcaaacctg tttgcgatcc tcggcctgcg tgcgatgtat    480
ttcctgctgg cgggcgtaaa gagcgtttct cgatgctcaa atagggctgg cggtgattcn    540
gggggttanc nggaac                                                    556

<210> 948
<211> 465
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (420)
<223> n equals a,t,g, or c

<400> 948
gcagagaccg aggctgcacc ggcagaggct gcggggcgga cgcgcgggcc ggcgcagcca     60
tggtgaagat tarcttccag cccgccgtgg ctggcatcaa gggcgacaag gctgacaagg    120
cgtcggcgtc ggcccctgcg ccggcctcgg ccaccgagat cctgctgacg ccggctaggg    180
aggagcagcc cccacaacat cgatccaaga gggggagctc agtgggcggc gtgtgctacc    240
tgtcgatggg catggtcgtg ctgctcatgg gcctcgtgtt cgcctctgtc tacatctgca    300
caattagaaa agtcctcaga agctttttct tkgaagggta cacttttctt actgtccyta    360
ttcctagacc tggggcttga gctgaggatg ggacgatgtg cccagggagg gacccaccan    420
agcacaagag aaggtggcta cctgggggtg tccaaggaac tttgt                    465

<210> 949
<211> 2370
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (678)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1752)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2313)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2315)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2369)
<223> n equals a,t,g, or c

<400> 949
agctgtcgcg rgcggcgccc ggccttgctc aacgcccagc agtccccacc gtcgctgccg     60
ccgccaccgc cctcggccgc tgccgaggcc tcctgcagcc atcatgtccg ccagcgccgt    120
ctacgtgctg gacctgaagg gcaaggtgct catctgccgg aactaccgtg gcgacgtgga    180
catgtcagag gtggagcact tcatgcccat cctgatggag aaggaggagg aggggatgct    240
gtcgcccatc ctggcccacg ggggggtccg tttcatgtgg atcaaacaca acaacctgta    300
tctggttgcc acatccaaga agaacgcgtg cgtgtcgctg gtcttttctt tcctctataa    360
ggtggtgcag gtgttttccg agtacttcaa ggagctggag gaggagagca tccgggacaa    420
ctttgttatc atctacgagc tgctggacga gctcatggac ttcggctacc cccagaccac    480
cgacagcaag atcctgcagg agtacatcac tcaggaaggc cacaagctgg aaacaggggc    540
cccgcggcca ccagccaccg tcaccaacgc ggtgtcctgg cggtccgaag gcatcaagta    600
tcggaagaat gaggtgttct tggacgtcat cgagtctgtc aacctcttgg tcagcgccaa    660
cggcaatgtc ctgcgcanga gatcgtgggc tccatcaaga tgcgagtctt cctctcgggc    720
atgcccgagc tgcgcctggg cctcaacgac aaggtcctct ttgacaacac gggccgcggc    780
aaaagcaaat ccgtggagct ggaggatgtg aagttccacc agtgtgtgcg gctatcacgc    840
ttcgagaatg accgcaccat ctccttcatc ccacccgacg gcgagttcga gctcatgtcc    900
taccgtctca acacccacgt caagcctttg atatggatcg agtcggtgat cgagaagcac    960
tcccacagcc gcatcgagta catgatcaag gccaaaagcc agttcaagcg gcggtcaaca   1020
gccaacaacg tggagatcca cattcccgtg cccaatgatg ccgactcacc caagttcaag   1080
acgacggtgg ggagcgttaa gtgggtcccc gagaacagcg agatygtgtg gtccatcaag   1140
tccttcccgg gcggcaagga gtacctgatg cgggcccact tcggcctgcc tagtgtggag   1200
gccgaagaca aggagggcaa gcccccgatc agtgtcaagt tcgagatccc ttacttcact   1260
acctccggca tccaggtgcg ctacctgaag atcattgaga agagtgggta ccaggccctg   1320
ccctgggtgc gttatatcac gcagaatgga gattaccagc tccggaccca gtgaggggct   1380
gtcgcagcca acaccccggc ctcggggctc ctggtggcag caccagggga cacacctgcc   1440
aaacccacca gatggagggg ccctccctgg tctctggcca ccctcccagc ctctgcccag   1500
ggacccctgc cttccccagg ccatctgctc tgccgtcgac actcgtctca gaagcccctt   1560
tcccagaaga ggctggtctt caagaagtct cgtttctttg cccctgaagt cagtttcagg   1620
ggaaggatgt gaaatttttc cgtgtagagg ttacagcctt ttatgctgtt gagctcccag   1680
gtaccaaaaa gcttggccaa cgcttgccag ccagccagct gcaggtggca tctgccacga   1740
aggaagcgcc ancctcgcca ggccagcagg ggcgtcgttt tgttgccatt ttgttgaacg   1800
ttatgggttt atgggtgttc ctggaacttg tctttgtgca ttcgttgctg tttgtgttac   1860
cctcactgtc cccatgtccc acccacgtcc tacggcactc aggaagcact tggtgaggac   1920
gagccctcac ccttcttgtc ttccttccca gcagcgcccg cagcgggcca tttacacgtc   1980
gaggctggca cctggcgcgc tcgggggcca ctgtagcgtc tgcctgctcc ctggactcgc   2040
aggcctcgcc tgtggcgcct tcccagggcc agcctgggtc acgagatgct gtcactcagc   2100
cagatcagta ttgacccacc aggggaggtg gggtttggtg agagacgcca gcctcagact   2160
ttttcccact gagggtccag agagcggggc cacgtgtcac ccacgtctgc gcttggtcac   2220
ccgtcctccc caccctgtgt gtgtttatgt catagttaca ttaaattcca ttcattgaat   2280
aaaaaaaaaa aaaaaaaaac tcgggactag ttntntcctc gggccgattt ggaagggttt   2340
tttttttttt tttgaaaaat ttaaaaaant                                    2370

<210> 950
<211> 2301
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2263)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2281)
<223> n equals a,t,g, or c

<400> 950
gcgacgctcg gcccgaagat ggcggccgaa tggggcggag gagtgggtta ctcgggctca     60
ggcccgggcc ggagccggtg gcgctggagc gggtctgtgt gggtccgaag cgttttactc    120
ctgttgggcg ggctccgggc cagcgccaca tctactcccg tctccttggg cagttcccct    180
ccctgccggc accacgtccc ctctgacact gaggtcataa ataaagttca tcttaaggca    240
aatcatgtgg tcaagagaga tgttgatgag catttaagaa tcaagactgt ctatgataaa    300
atgktgaasa gttgctccct gagaaaaaga atcttgtaaa gaacaagctt ctcccacawg    360
cgatttctta tttagagaag acttttcagg tccgtcgacc tgcgggcact atcttactta    420
gcagacaatg tgcaacaaac caatacctcc ggaaggaaaa cgatcctcac aggtactgca    480
ccggggagtg tgccgcacac acaaagtgcg gccccgttat tgttcctgag gaacatctcc    540
agcaatgccg ggtctaccgt gggggtaagt ggcctcatgg agcagtgggt gtgccagacc    600
aagaaggcat ctcagatgca gactttgttc tttacgttgg tgctctggcc accgagagat    660
gcagccatga aaacatcatc tcttatgcag cctattgtca gcaggaagca aacatggaca    720
ggccaatagc aggatatgct aacctgtgtc caaatatgat ctctacccag cctcaggagt    780
ttgttgggat gctgtccaca gtgaaacatg aggttattca tgccctgggt ttctctgctg    840
ggctgtttgc attctaccat gataaagatg gaaatcctct cacttcaaga tttgcagatg    900
gcctyccacc ttttaattat agtctgggat tatatcaatg gagtgataaa gtagttcgaa    960
aagtgragag attatgggat gttcgagata ataagatagt tcgtcacact gtgtatctcc   1020
tggtaacgcc tcgtgttgtt gaggaagcac gaaaacattt tgattgtcca gttctagagg   1080
gaatggaact tgaaaatcaa ggtggtgtgg gcactgagct caaccattgg gaaaaaaggt   1140
tattagagaa tgaagcgatg actggttctc acactcagaa tcgagtactc tctcgaatca   1200
ctctggcatt aatggaggac actggctggt ataaagcaaa ttacagcatg gctgagaagt   1260
tagactgggg ccgaggaatg ggctgtgact ttgtcaggaa gagctgtaaa ttctggattg   1320
atcagcagag acaaaagaga cagatgctga gcccttactg tgacacgctc agaagtaacc   1380
cactgcagct aacttgcaga caggaccaga gagcagttgc cgtgtgtaat ttgcagaagt   1440
tccctaagcc tttaccacag gaataccagt actttgatga actcagtgga atacctgcag   1500
aagatttgcc ttattatggt ggctccgtgg aaattgctga ctactgscct ttcagtcagg   1560
aattcagttg gcatttaagt ggtgaatatc agcgcagctc agattgtaga atattggaaa   1620
atcaaccaga aatttttaag aactatggcg ctgaaaagta tggacctcat tccgtttgtc   1680
taattcagaa atcagcattc gttatggaga agtgtgagag gaagctgagt tacccagact   1740
ggggaagcgg atgctatcag gtttcttgtt ctcctcaagg tctgaaagtt tgggtccaag   1800
atacttcata tttgtgtagt cgggctgggc aggtcctccc tgtcagtatc cagatgaatg   1860
gctggattca cgatggaaac ctgctctgcc catcatgttg ggacttctgt gagctctgtc   1920
ctccagaaac agatcctcca gccactaacc tgacccgagc tctgccactt gatctttgtt   1980
cctgttcctc gagcctggtg gtcaccctct ggcttctgct aggcaatctg tttcctctgc   2040
tggctggatt tcttctgtgt atatggcact aggaatggaa aagtggatct tcaagatatt   2100
cttttatgtt atgttcttgt gaacaaagca caaagtttga gtgagtgcca acctatgcag   2160
atggtagaag tggcattcct ggctttggct tggaagaatt gacgaccatc agaccttgaa   2220
gcagaacttc acagcagcct gtcctcatca gcaacccaac cancttcatc agcaacccaa   2280
ncaccttcat cagcaaccca a                                             2301

<210> 951
<211> 2205
<212> DNA
<213> Homo sapiens

<400> 951
gttccagaca tgtttgcaga ctctaatgaa aatgagactg tctttgctcc tgtcatccag     60
gctggcatgg aagcactaaa ggcagcagac tgtcctggga agctgttcat cttccattct    120
tccttgccaa ctgctgaagc accagggaag ctcaaaaaca gagatgacaa aaaactggtt    180
aatacagaca aagagaagat acttttccag ccccaaacaa atgtctatga ctcattggcc    240
aaggactgcg tggctcacgg ctgctctgtg acactcttcc tctttcctag tcagtatgtg    300
gacgtggcct cgctggggct ggttcctcag ctcactggag gaacccttta caaatacaac    360
aatttccaga tgcacttgga tagacaacaa tttttgaacg acctcagaaa tgatattgaa    420
aagaaaatag gctttgatgc tattatgagg gttcgtacca gcacaggttt cagagccact    480
gatttctttg gtggaatctt gatgaacaac accaccgatg tagaaatggc tgccatcgat    540
tgtgacaagg cagtgaccgt ggagttcaag cacgatgaca aactcagtga agacagtgga    600
gccttaatcc agtgtgctgt gctttacacg acaatcagtg gtcaaagaag acttcggatt    660
cacaatcttg gcttaaactg cagctctcag ctagctgatc tttataagag ctgtgagaca    720
gatgctctta tcaacttctt tgccaagtca gcttttaaag cagttctcca ccagcctttg    780
aaggtcatcc gggaaattct agttaatcag actgcccata tgttggcatg ttaccggaag    840
aattgtgcaa gtccttctgc agcaagccag cttattctac cagattccat gaaagtattg    900
ccagtgtaca tgaattgctt gttgaaaaac tgtgtactac tcagcagacc agagatctca    960
actgatgaac gagcatacca gagacagctg gtcatgacca tgggtgtggc tgactctcag   1020
cttttcttct acccacaact tctgcccata cacacgttag atgtcaagag tacaatgtta   1080
cctgctgccg ttcgttgctc tgagtcccgt ctttcagaag aaggaatatt cttactggct   1140
aatggtctac acatgttcct gtggttggga gtaagcagcc caccagaact gatccaagga   1200
atatttaatg tgccatcttt tgcacatatc aacacagata tgacattgct gcctgaagtg   1260
ggaaacccat actctcaaca actcagaatg ataatgggta ttatccaaca aaagaggcca   1320
tattcaatga agctcacaat tgtaaagcag cgagaacaac cagaaatggt tttccgacag   1380
ttcctggtag aagacaaagg actttacgga ggctcttctt atgtggattt cctttgttgt   1440
gttcacaagg agatctgtca gctgcttaat taattgaaac ttctctgtca ttgatgttgc   1500
atttccaagg agataatctc cttcttggtg cctaattttc tagatgataa taggctagtt   1560
ttgatttctt gctcattttc agaataactt tccaggaaga gatggcattt agaacttcag   1620
ctttggtgct caggtataaa gccaattaag gtacaattgt accataaagg gaacaatctg   1680
tttctgattg cacagtttct aatttttaaa actgatgtgg tttgcatttc ataaaaggca   1740
aagtttacag aaccataaac attctcaatt ttctttatgc tagacatata aattattttt   1800
caaactgtat agatttgggg taaaaagttg tctcagttcc tctcccaatt gcaatgagaa   1860
aaaaaagctt aatttttaca ttatacttaa ttttctaaaa ccatgtaact ccattgaaca   1920
catttttcaa cttaaggtct gcatagcaga cttttaataa ccttgggatt tatctggtag   1980
aacaatatgt gttctacatt tttttcataa ttatatattg tgtatgttaa aactattttc   2040
cagttgtttt gtctgtaaaa ctgtctttat caatatgctt aatggttctt tgtacaattt   2100
tgaaagtttc tacctgtata taatggatgt taaccagtat caataaatca cttcgtataa   2160
tcttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                   2205

<210> 952
<211> 1703
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1689)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1703)
<223> n equals a,t,g, or c

<400> 952
cacgtgctag gtgcccatct ggtgctgcgg cacggctacc acctnaccac ctttctgcga     60
cacttctggc ccaccaccct gacggacccc actttggccg caatcacatt taccaaggga    120
cattggagct ccccacacca ctcattgctg cccaccagct atacaactac gtggctgatc    180
acgccagctc ttaccacatg aagccattgc gaatggcccg gccagggggc ccagaacaca    240
acgagtatgc cctggtgtcg gcatggcaca gttctggctc ctacctggac tctgagggac    300
ttcgacacca ggatgacttt gatgtgtctc tgcttgtctg tcactgtgct gcaccctttg    360
aggagcaagg agaggctgag cggcacgttc tgcggctaca gttcttcgtg gtgctcacca    420
gccagcgaga gctcttcccc aggctcactg ctgacatgcg ccgsttccgg aagccaccca    480
gactgccccc tgagccagag gctcctggga gttcagctgg cagccctggg gaggcctcag    540
ggcttattct agcgcctgga ccggctcctc tgttcccacc actggctgca gaggtgggca    600
tggcacgagc acggctggct cagctggtgc ggctggctgg agggcactgc cgtcgggaca    660
ccctttggaa gcgcctcttc ttgctggagc caccggggcc tgatcgactg cggctagggg    720
ggcgcctggc cctggcagag ctggaggaac tcctagaagc agtccatgcc aaatccattg    780
gggacatcga cccccagctg gactgcttcc tatccatgac ggtctcctgg taccagagcc    840
tgatcaaagt tctcctaagc cgcttccccc agagctgtcg ccatttccaa agcccagact    900
tgggaactca gtacctggtt gtgctgaatc agaagttcac tgactgcttt gtgctagtgt    960
ttctggactc ccacttagga aagacgtctc tgacagtggt tttccgagag cccttcccag   1020
tacagcccca ggacagcgag agcccccctg cccaactggt ctccacctac caccacctgg   1080
agtctgtcat caacacagcc tgtttcaccc tctggacccg cctcctctga gggagtggac   1140
tggaccactg aatgtcactg ttccttgaat catgggccta ccagattgcc tgccagaggc   1200
aggactgacc agcccttctg ggccccaggg caagccagac actgagtgac accaaaggct   1260
ttgtaactat gtcttgaggg tctgctgccc cagcctggca gcaggaaccg ccctccccaa   1320
acacccacag ccactgaccc atccaggact ccagagagtc aggtcaaccc cgaggacccc   1380
ttgggccctt ctggggtact cctttcggcc cccctggtag agtctcggga gttcacacag   1440
ggtggcaaac accccctaga gctcctctgc ctgaatcctg ccccctagcc tttgaccact   1500
gtcagccacc tgtgtccctt gagccttcgg gtcttcactt cccacttgga catcactgct   1560
ggacattccc atcgagatga cacctgggtt ccaatcccag ctctgccttt gaagcacwtr   1620
cggccaccgt caagtccctt tgctctcgga ccctgggttt ctsatcsttt aatkaaatra   1680
attcagggng gtttccagac ctn                                           1703

<210> 953
<211> 2938
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (491)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1987)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1994)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2892)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2932)
<223> n equals a,t,g, or c

<400> 953
ggcacgagcc agccttctgg ccctaagggc ctagagccac cagaagaaga gaagaatccc     60
tacaaagaag tgtacacgga catgtgggtg gaacctgagg cagctgccta cgcaccacct    120
ccaccagcca aaaagccccg gaagagcaca gcggagaagc ccaaggtcaa ggagattatt    180
gatgagcgca caagagagcg gctggtgtac gaggtgcggc agaagtgccg gaacattgag    240
gacatctgca tctcctgtgg gagcctcaat gttaccctgg aacaccccct cttcgttgga    300
ggaatgtgcc aaaactgcaa gaactgcttt ctggagtgtg cgtaccagta cgacgacgac    360
ggctaccagt cctactgcac catctgctgt gggggccgtg aggtgctcat gtgcggaaac    420
aacaactgct gcaggtgctt ttgcgtggag tgtgtggacc tcttggtggg gccgggggct    480
gsccargcag ncattaagga agacccctgg aactgctaca tgtgcgggca caagggtacc    540
tacgggctgc tgcggcggcg agaggactgg ccctcccggy tccagatgtt cttcgctaat    600
aaccacgacc aggaatttga ccctccaaag gtttacccac ctgtcccagc tgagaagagg    660
aagcccatcc gggtgctgtc tctctttgat ggaatcgcta cagggctcct ggtgctgaag    720
gacttgggca ttcaggtgga ccgctacatt gcctcggarg tgtgtgagga ctccatcacg    780
gtgggcatgg tgcggcacca ggggaagatc atgtacgtcg gggacgtccg cagcgtcaca    840
cagaagcata tccaggagtg gggcccattc gatctggtga ttgggggcag tccctgcaat    900
gacctctcca tcgtcaaccc tgctcgcaag ggcctctacg agggcactgg ccggctcttc    960
tttgagttct accgcctcct gcatgatgcg cggcccaagg agggagatga tcgccccttc   1020
ttctggctct ttgagaatgt ggtggccatg ggcgttagtg acaagaggga catctcgcga   1080
tttctcgagt ccaaccctgt gatgattgat gccaaagaag tgtcagctgc acacagggcc   1140
cgctacttct ggggtaacct tcccggtatg aacaggccgt tggcatccac tgtgaatgat   1200
aagctggagc tgcaggagtg tctggagcat ggcaggatag ccaagttcag caaagtgagg   1260
accattacta cgaggtcaaa ctccataaag cagggcaaag accagcattt tcctgtcttc   1320
atgaatgaga aagaggacat cttatggtgc actgaaatgg aaagggtatt tggtttccca   1380
gtccactata ctgacgtctc caacatgagc cgcttggcga ggcagagact gctgggccgg   1440
tcatggagcg tgccagtcat ccgccacctc ttcgctccgc tgaaggagta ttttgcgtgt   1500
gtgtaaggga catgggggca aactgaggta gcgacacaaa gttaaacaaa caaacaaaaa   1560
acacaaaaca taataaaaca ccaagaacat gaggatggag agaagtatca gcacccagaa   1620
gagaaaaagg aatttaaaac aaaaaccaca gaggcggaaa taccggaggg ctttgccttg   1680
cgaaaagggt tggacatcat ctcctgattt ttcaatgtta ttcttcagtc ctatttaaaa   1740
acaaaaccaa gctcccttcc cttcctcccc cttccctttt ttttcggtca gaccttttat   1800
tttctactct tttcagaggg gttttctgtt tgtttgggtt ttgtttcttg ctgtgactga   1860
aacaagaagg ttattgcagc aaaaatcagt aacaaaaaat agtaacaata ccttgcagag   1920
gaaaggtggg agagaggaaa aaaggaaatt ctatagaaat ctatatattg ggttgttttt   1980
ttttktnttt tttntttttt tttttttggg tttttttttt ttactatata tctttttttt   2040
gttgtctcta gcctgatcag ataggagcac aagcagggga cggaaagaga gagacactca   2100
ggcggcacat ttccctccca gccactgagc tgtcgtgcca gcaccattcc tggtcacgca   2160
aaacagaacc cagttagcag cagggagacg agaacaccac acaagacatt tttctacagt   2220
atttcaggtg cctaccacac aggaaacctt gaagaaaatc agtttctaga agccgctgtt   2280
acctcttgtt tacagtttat atatatatga tagatatgag atatatatat aaaaggtact   2340
gttaactact gtacaacccg acttcataat ggtgctttca aacagcgaga tgagtaaaaa   2400
catcagcttc cacgttgcct tctgcgcaaa gggtttcacc aaggatggag aaagggagac   2460
agcttgcaga tggcgcgttc tcacggtggg ctcttcccct tggtttgtaa cgaagtgaag   2520
gaggagaact tgggagccag gttctccctg ccaaaaaggg ggctagatga ggtggtcggg   2580
cccgtggaca gctgagagtg ggattcatcc agactcatgc aataaccctt tgattgtttt   2640
ctaaaaggag actccctcgg caagatggca gagggtacgg agtcttcagg cccagtttct   2700
cactttagcc aattcgaggg ctccttgtgg tgggatcaga actaatccag agtgtgggaa   2760
agtgacagtc aaaaccccac ctggagcaaa taaaaaaaca tacaaaacgt actggtgctt   2820
tcctgtctaa gtcgcctttt gtgtgttctt ttatgaggcc cccaccatcc acccctctgt   2880
gcacaaggcg gnttccggcc cctggaatgt gatgtttttg gtcatctcca angctgca     2938

<210> 954
<211> 1751
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1716)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1723)
<223> n equals a,t,g, or c

<400> 954
aattcggcac gagaccttta gggtgcgcgg gtgcagtata tctcgcgctc tctccccttt     60
ccccctcccc tttccccacc ccgggcgctc aggttggtct ggaccggaag cgaagatggc    120
gacttctggc gcggcctcgg cggagctggt gatcggctgg tgcatattcg gcctcttact    180
actggctatt ttggcattct gctggatata tgttcgtaaa taccaaagtc ggcgggaaag    240
tgaagttgtc tccaccataa cagcaatttt ttctctagca attgcactta tcacatcagc    300
acttctacca gtggatatat ttttggtttc ttacatgaaa aatcaaaatg gtacatttaa    360
ggactgggct aatgctaatg tcagcagaca gattgaggac actgtattat acggttacta    420
tactttatat tctgttatat tgttctgtgt gttcttctgg atcccttttg tctacttcta    480
ttatgaagaa aaggatgatg atgatactag taaatgtact caaattaaaa cggcactcaa    540
gtatactttg ggatttgttg tgatttgtgc actgcttctt ttagttggtg cctttgttcc    600
attgaatgtt cccaataaca aaaattctac agagtgggaa aaagtgaagt ccctatttga    660
agaacttgga agtagtcatg gtttagctgc attgtcattt tctatcagtt ctctgacctt    720
gattggaatg ttggcagcta taacttacac agcctatggc atgtctgcgt tacctttaaa    780
tctgataaaa ggcactagaa gcgctgctta tgaacgtttg gaaaacactg aagacattga    840
agaagtagaa caacacattc aaacgattaa atcaaaaagc aaagatggtc gacctttgcc    900
agcaagggat aaacgcgcct taaaacaatt tgaagaaagg ttacgaacac ttaagaagag    960
agagaggcat ttagaattca ttgaaaacag ctggtggaca aaattttgtg gcgctctgcg   1020
tcccctgaag atcgtctggg gaatattttt catcttagtt gcattgctgt ttgtaatttc   1080
tctcttcttg tcaaatttag ataaagctct tcattcagct ggaatagatt ctggtttcat   1140
aatttttgga gctaacctga gtaatccact gaatatgctt ttgcctttac tacaaacagt   1200
tttccctctt gattatattc ttataacaat tattattatg tactttattt ttacttcaat   1260
ggcaggaatt cgaaatattg gcatatggtt cttttggatt agattatata aaatcagaag   1320
aggtagaacc aggccccaag cactcctttt tctctgcatg atacttctgc ttattgtcct   1380
tcacactagc tacatgattt atagtcttgc tccccaatat gttatgtatg gaagccaaaa   1440
ttacttaata gagactaata taacttctga taatcataaa ggcaattcaa ccctttctgt   1500
gccaaagaga tgtgatgcag atgctcctga agatcagtgt actgttaccc ggacatacct   1560
attccttcac aagttctggt tcttcagtgc tgcttactat tttggtaact gggcctttct   1620
tggggtattt ttgattggat taattgtatc ctgttgtaaa gggaagaaat cggttattga   1680
aggagtagat gaagattcag acataagagt tgtccntgag aancttggtg tgcttgaaca   1740
gacgggcccc t                                                        1751

<210> 955
<211> 729
<212> DNA
<213> Homo sapiens

<400> 955
agattatctg ctgtatcggc tcattttctc agtgagcaag cagtttcaaa gcttgccagg     60
gttttgggat acagttgggt tcaaacacag atatattaaa ggaagaatca tggataatat    120
cttgagttcc ttgtttctct ccgtgcagtt tcaagtgaac ctcaaaccct ggcaagcttt    180
gaaactgctt gctcactgag aaaatgagcc gatacagcag ataatctaca gctgcaawca    240
gcacccagat gcagagatgg ataagtatgg ggaggaaaaa cagccccagg tttttccttt    300
ctttaggagt cggccagaaa gtcgggatga tgacatactt cctcctttcc tccttattca    360
gcgggagcac acagggcctc tgttgatgtc tctccctttc atcaaactga acaaattgtc    420
tggtgatgta gatgttttca tacttccaac cacaagggcc caaaaatcgc ttcatgaaga    480
ggccagtgcc aagcaggacg agcgaaagcc ctgcaaaggc aagtagcttc tgacccaggg    540
aggacaacac ctctgtggtt tgttgccatc tggtacaaga cgctcaggac ttcccctttg    600
ctgtcattta gctgtgcctc caggacatgg ctgggactga aaagagagac tgccagggtc    660
tggttccaag aaacaaggtc atcaaataca cttagtggag tggcaaggcc ataaatccac    720
tgaattgcc                                                            729

<210> 956
<211> 1439
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> n equals a,t,g, or c

<400> 956
tcgacccacg cgtccggaac gtgctccgcg ggctcagtcc gcccgccgct gcgtccgcgg     60
agtgcaagtg agcttctcgg ctgccccgcg ggccggggtg cgganccgac atgcgcccgc    120
ttctcggcct ccttctggtc ttcgccggct gcaccttcgc cttgtacttg ctgtcgacgc    180
gactgccccg cgggcggaga ctgggctcca ccgaggaggc tggaggcagg tcgctgtggt    240
tcccctccga cctggcagag ctgcgggagc tctctgaggt ccttcgagag taccggaagg    300
agcaccaggc ctacgtgttc ctgctcttct gcggcgccta cctctacaaa cagggctttg    360
ccatccccgg ctccagcttc ctgaatgttt tagctggtgc cttgtttggg ccatggctgg    420
ggcttctgct gtgctgtgtg ttgacctcgg tgggtgccac atgctgctac ctgctctcca    480
gtatttttgg caaacagttg gtggtgtcct actttcctga taaagtggcc ctgctgcaga    540
gaaaggtgga ggagaacaga aacagcttgt tttttttctt attgtttttg agacttttcc    600
ccatgacacc aaactggttc ttgaacctct cggccccaat tctgaacatt cccatcgtgc    660
agttcttctt ctcagttctt atcggtttga tcccatataa tttcatctgt gtgcagacag    720
ggtccatcct gtcaacccta acctctctgg atgctctttt ctcctgggac actgtcttta    780
agctgttggc cattgccatg gtggcattaa ttcctggaac cctcattaaa aaatttagtc    840
agaaacatct gcaattgaat gaaacaagta ctgctaatca tatacacagt agaaaagaca    900
catgatctgg attttctgtt tgccacatcc ctggactcag ttgcttattt gtgtaatgga    960
tgtggtcctc taaagcccct cattgttttt gattgccttc tataggtgat gtggacactg   1020
tgcatcaatg tgcagtgtct tttcagaaag gacactctgc tcttgaaggt gtattacatc   1080
aggttttcaa accagccctg gtgtagcaga cactgcaaca gatgcctcct agaaaatgct   1140
gtttgtggcc gggcgcggtg gctcacgcct gtaatcccag cactttggga ggccgaggcc   1200
ggtgattcac aagktcagga gttcaagacc agcctggcca agatggtgaa atcctgtctc   1260
taataaaaat acaaaaatta gccaggcgtg gtggcaggca cctgtaatcc cagctactcg   1320
ggaggctgag gcaggagaat tgcttgaacc aaggtggcag aggttgcagt aagccaagat   1380
cacaccactg cactccagcc tgggtgatag agtgagacac tgtcttgaca aaaaaaaaa    1439

<210> 957
<211> 1616
<212> DNA
<213> Homo sapiens

<400> 957
ctctcattgg ctctgctgca sccctgacca acgctccaat aggccgggat ccagccatac     60
ttcaatggat cccaggggta tcttgaaggc atttcccaag cggcagaaaa ttcatgctga    120
tgcatcatca aaagtacttg caaagattcc taggagggaa gagggagaag aagcagaagg    180
aggcctgcag tatccctggg attgggaakc ggatggctga saaaatcata gagatcctgg    240
agagcgggca tttgcggaag ctggaccata tcagtgagag cgtgcctgtm ttggagctct    300
tctccaacat ctggggagct gggaccaaga ctgcccagat gtggtaccaa cagggcttcc    360
gaagtctgga agacatccgc agccaggcct ccctgacaac ccagcaggcc atcggcctga    420
agcattacag tgacttcctg gaacgtatgc ccagggagga ggctacagag attgagcaga    480
cagtccagaa agcagcccag gcctttaact cygggctgct gtgtgtggca tgtggttcat    540
accgacgggg aaaggcgacc tgtggtgatg tcgacgtgct catcactcac ccagatggcy    600
ggtcccaccg ggktatcttc agccgcctcc ttgacagtct tcggcaggaa gggttcctca    660
cagatgactt ggtgagccaa gaggagaatg gtcagcaaca gaagtacttg ggggtgtgcc    720
ggctcccagg gccagggcgg cggcaccggc gcctggacat catcgtggtg ccctatagcg    780
agtttgcctg tgccctgctc tacttcaccg gctctgcaca cttcaaccgc tccatgcgag    840
ccctggccaa aaccaagggc atgagtctgt cagaacatgc cctcagcact gctgtggtcc    900
ggaacaccca tggctgcaag gtggggcctg gccgagtgct gcccactccc actgagaagg    960
atgtcttcag gctcttaggc ctcccctacc gagaacctgc tgagcgggac tggtgaccca   1020
tggctggggg tgctgaggag agccgagttg gactggctac ccctcctggc cacccagtac   1080
tccctccagc ctcagctggc tgaacctcgc cgctccaacc accagcttcc tcagcgagca   1140
gggcccaggg ctctgggcmt gaagcaagag ccagcccggc tcccagtgtc tgcccggctc   1200
ccagtgtctg cccagccctc tcccagacag gagcaggctg ccaccccttc tacctcacca   1260
ctgcccctcg aagaattttg caaatggccc cttgccccat tttaagcagg agcaggtggc   1320
tggtttgaag ccccaggtat cccccttccc tgctatggga aaggccaagc tgctgggtgg   1380
ggacagaagc tgcaggggag agggaagcag ccgtgctgtc aacatcatcc ggcaccctct   1440
ggggtaggag aacagccatt ccacatgtgt tccctctatc cgtcctgctt ccyggkcagc   1500
tggtggtgct gggaatgggg tgccccagcc ttggtgagga cagtgttggg caggcccagg   1560
ggcccagtaa agtgcatttg acattgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa       1616

<210> 958
<211> 1721
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1569)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1707)
<223> n equals a,t,g, or c

<400> 958
gctttttccc cgccatgatc aagtctgcgg cacaccctca ttctcagtgt tcttcccatc     60
tgggtggaga gacgcctcct ggctgtggca caaggctccc agcgctacgc ggtcatgaga    120
gcggcggaaa tgcaccagtt gaaggacagc agccgtgggg aggcgagcaa cccggacttt    180
gggaaaacca tcagagasct gcctctctcc atctggctcc tgctgaagaa ccccacgttc    240
atcctgctct gcctggccgg ggccaccgag gccactctca tcaccggcat gtccacgttc    300
agccccaagt tcttggagtc ccagttcagc ctgagtgcct cagaagctgc caccttgttt    360
gggtacctgg tggtgccagc gggtggtggc ggcaccttcc tgggcggctt ctttgtgaac    420
aagctcaggc tccggggctc cgcggtcatc aagttctgcc tgttctgcac cgttgtcagc    480
ytgctgggca tcctcgtctt ctcactgcac tgccccagtg tgcccatgcg ggcstcacag    540
ccagctacgg cgggasstcc tgcccgaagc cacctgaacc taacggctcc ctgcaacgct    600
gcctgcactg ccagccagaa cactacagcc ctgtgtgcgg ctcggacggc ctcatgtact    660
tctcactgtg ccacgcaggt gccctgcagc cacggagacg aatgtggacg gccagaaggt    720
gtaccgagac tgtagctgta tccctcagaa tctttcctct ggttttggcc atgccactgc    780
agggaaatgc acttcaactt gtcagagaaa gcccctcctt ctggttttca tattcgttgt    840
aattttcttt acattcctca gcagcattcc tgcactaacg gcaactctac gatgtgtccg    900
tgaccctcag agatcctttg ccctgggaat ccagtggatt gtagttagaa tactaggggg    960
catcccgggg cccatcgcct tcggctgggt gatcgacaag gcctgtctgc tgtggcagga   1020
ccagtgtggc cagcagggct cctgcttggt gtaccagaat cggccatgag ccgctacata   1080
ctcatcatgg ggctcctgta caaggtgctg ggcgtcctct tctttgccat agcctgcttc   1140
ttatacaagc ccctgtcgga gtcttcagat ggcctggaaa cttgtctgcc cagccagtcc   1200
tcagcccctg acagtgccac agatagccag ctccagagca gcgtctgacc accgcccgcg   1260
cccacccggc cacggcgggc actcagcatt tcctgatgac agaacagtgc cgttgggtga   1320
tgcaatcaca cgggaacttc tatttgacct gcaaccttct acttaacctg tggtttaaag   1380
tcggctgtga cctcctgtcc ccagagctgt acggccctgc agtgggtggg aggaacttgc   1440
ataaatatat atttatggac acacagtttg catcagaacg tgtttataga atgtgtttta   1500
tacccgatcg tgtgtggtgt gcgtgaggac aaactccgca ggggctgtga atcccactgg   1560
gagggcggng ggcctgcagc ccgaggaagg cttgtgtgtc ctcagttaaa actgtgcata   1620
tcgaaatata ttttgttatt taagcctgaa aaaaaaaaaa aaaaaaaaaa aaaaaactcg   1680
agggggggtc ccgtacccaa tctcctnatc atgcatcgta t                       1721

<210> 959
<211> 3992
<212> DNA
<213> Homo sapiens

<400> 959
ccggccccgg cccctggcga gatgccgtgt ggggaggatt ggctcagcca cccgctggga     60
atcgtgcagg gattcttcgc ccaaaatgga gttaatcctg actgggagaa gaaagtaatt    120
gagtatttta aggaaaagct gaaggaaaat aatgctccta agtgggtacc atcactgaac    180
gaagttcccc ttcattattt gaaacctaat agttttgtga aatttcgttg catgattcag    240
gatatgtttg accctgagtt ttacatggga gtttatgaaa cggttaacca aaacacaaaa    300
gcacatgttc ttcattttgg aaaatataga gatgtagcag agtgtgggcc tcaacaagaa    360
cttgatttaa actctccacg aaataccact ttggaaagac agactttcta ttgtgttccg    420
gtgcctgggg aatctacgtg ggtaaaagaa gcctatgtta atgcaaacca agctcgagtc    480
agtccctcaa catcctacac tcctagtcgc cacaagagga gttatgaaga tgatgacgat    540
atggacctac agcccaataa gcagaaagac caacatgcag gtgccagaca agcagggagt    600
gttggtggtc ttcaatggtg tggagagcca aaacgtttag aaactgaagc ttctactggg    660
caacagctga actctctgaa cttgtcttct ccttttgatt tgaattttcc attgccagga    720
gagaagggcc ctgcatgcct tgtgaaggtt tatgaagatt gggattgttt caaagtaaat    780
gacattcttg agctatatgg catactgtct gtggatcctg tgctgagtat actgaataat    840
gatgaaaggg atgcctctgc actgctggat ccgatggagt gcacagacac agcagaggag    900
cagagagtac acagtcctcc tgcttcatta gtgccgagaa ttcatgtgat cttagcccag    960
aagttgcaac acatcaaccc attattgcct gcctgcctta acaaagagga gagcaaaacc   1020
tgtaagtttg tttcaagttt catgtccgaa ttgtctccag tcagagcaga acttcttggg   1080
ttccttactc atgcccttct gggggatagt ttggctgctg aataccttat attacatctc   1140
atctccacag tatatacaag aagagatgtc cttccactag gaaaatttac agttaacttg   1200
agtggttgcc cacggaatag taccttcaca gaacacttgt atcgaattat tcaacatctt   1260
gttccagcat cttttcgtct gcagatgact atagagaaca tgaaccattt gaaattcatt   1320
ccccacaaag actacacagc caatcgcttg gtcagtgggc tcctccagct gcccagcaat   1380
acttcccttg taatcgatga gactctcctg gaacaggggc agctggatac cccaggtgtt   1440
cataatgtga cagccctgag caacctcata acgtggcaga aggtggatta tgacttcagc   1500
taccatcaga tggaattccc ctgcaatatt aacgttttca ttacttcgga ggggaggtca   1560
ctcctcccgg cagactgcca gattcactta cagccccagc taattccacc aaacatggag   1620
gagtacatga acagccttct ctcagcggtg ctgccttccg tgctgaacaa attccgcatt   1680
tatctaactc ttttgagatt cttggaatat agcatatctg atgaaataac caaggcagtt   1740
gaagatgact ttgtggaaat gcggaagaac gaccctcaga gcatcactgc tgatgatctt   1800
caccagctgc tcgtggtggc tcggtgtctg tctctcagtg ctggtcagac aacgctgtca   1860
agagaacgat ggctgagagc aaagcagcta gagtctttaa gaagaacgag gcttcagcag   1920
caaaaatgtg tgaatggaaa tgaactttaa agatgtaata cctatgaaga gtaatgggca   1980
aactgtagcc acataattgt aaaattcaga tattcattta taccacattg ttttataggt   2040
aatttctatc acaaaccagt gacatttcct gaaatcaagc ctggtaacac ctgatgttta   2100
tatgatattc agtaaggact tttaccttac tgatttcatg gagcttttga agtttgtttt   2160
ataataatta tataaattag taatgatgta aaaaaagtat ttgatattaa aagtttaata   2220
ttgawaatgt tgctgattgt accatttcct tagcttcagc tgagtcatag gccagactgt   2280
tgaaatgctg aaatgaagaa ggttgttgca gtttcaaagt cagaggaatc gtgcttcgga   2340
tttcttatgt tttctagttc tctgtttttc cagttcacag tgggttgggg tgcattcagt   2400
agtccatctt tggggaacgg aggcgtactt gccattgatt cacatgacta catgaaattc   2460
tgtactgtca tttcccagat gtttggccac agaaactttt tcccacttaa catttgttaa   2520
cagcctgcaa aactaaactt gtacatggca gtggttccca gacttttgta ttttatggac   2580
cggtagtaat atttccaaaa atctggggta ctataaggtt gccaatttac cttgccaagt   2640
aatccgaata aatcactgta ttatcaccat ttttttcata aaaggaaagg acaatctatc   2700
tctgaataag aggagtcctt taaacggaat gaatgtggct tttgggggca aaagaaacca   2760
agacactaca ttgtctttat tttctcctat cccagtgcat ttgagaacca tgcataaggg   2820
aatgctgtgc tacaaagctg tgcccaaata tgaaaacaaa ataggaaact taaaaagcaa   2880
tacccccttt agaaagtttt tattttctta aatgtcattg agttgctttg attctattgg   2940
atttttggca ttttttatgg gatcatcagt tggttccaag tatgttagat cagctaacat   3000
ctgctactcc agtaacagcc tcgtacaact gcaggtaggt tttctccaga ccaattagtt   3060
ttaatagagc aaactaacaa cagactgtag tagcatggtt atggcaacca gaatcttcag   3120
aaaggttagg acattacttt ttaagctgtc agtggtatca artaacttac ctagttggag   3180
gcagataaag gatcccttac gttttttcct ataaggccta aattgaaatt gttaaccaag   3240
gaaacagggt cagccttgaa aaatcaagga attcattgta cctaataact gaagtaaaaa   3300
taactagttg ttcaactttt cctaaactca aatctatttt tataaacaaa tgtaaataat   3360
gtttatatta gagttgaact ggttttcatt tttataactg gtagactaga ccttccttaa   3420
acttttagaa ataaaatgaa ggcttcactg gatttgtgag gataaaatac attttcttta   3480
attgtcctag agcaaagtac attagtcacc atgtgttttt tgtgccaatg taamttgtaa   3540
tttaccaaag aaaaatacat acattgcttg gtcttgcaga aaagttccct tgaaagaacc   3600
tttccaataa ataaaacgtc ccaaattagc agtaccttgg gctgtttttc atgagtaaga   3660
agattcacca tcccatgtga tctgtgtgga aaaagaccat gtcctcttgg tggaagacat   3720
gagagagctg aactgaagtg gaggaggtgg tgcaagaggg accttcctgc tcaaggcccg   3780
cccaggcagc ggaatggagt gcagtgcttg gctgcagaaa ccctttgtcc ctcacctata   3840
tatacacgga cagtcaagtt tgttgctcta acgtaaggca cagcgttaat cctgtatggc   3900
caggaaactg agtagactcc tgtgtaaccc tgtttggaac tttgccttct taaaatgatt   3960
tttcaaagat ctctttcgaa ctaaaaaaaa aa                                 3992

<210> 960
<211> 1986
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1049)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1774)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1933)
<223> n equals a,t,g, or c

<400> 960
ggccgtggag cgcactgacg agctggtccg ggagtacctg ctcttccgcg ggttcacgca     60
cacactgcgg cagctggacg ccgagatcaa ggcggacaag gagaaggggt tccgggtgga    120
taagattgtg gaccagctgc agcagttaat gcaggtgtat gacttggctg cccttcggga    180
ttattggagc tacttggagc gtcggctctt cagccgcttg gaggatatat acagacccac    240
aatccacrag ctgaaaacca gcctgtttcg attttatctt gtctacacaa tccagacaaa    300
cagaaatgac aaggctcagg agttctttgc aaagcaggcc acggaactcc agaaccaggc    360
tgagtggaag gattggtttg tcctgccctt cctgccatcc ccggacacca accccacctt    420
tgctacctac ttttctcgac agtgggctga caccttcatt gtgtccctgc acaacttcct    480
gagcgtcctg tttcagtgca tgccagtccc tgtgatcctg aactttgatg cggagtgtca    540
gaggactaac caggttcaag aagaaaatga agttctgcgt cagaagcttt ttgcattgca    600
agctgaaatc caccgactga agaaagagga gcaacagcca gaagaggaag aggccttggt    660
ccaacacaaa ttgcctcctt atgtctccaa catggaccgc ctgggggact cggaacttgc    720
catggtgtgc agccaaagga atgcctccct ctcccagtca cytcgtgtgg gcttcctgtc    780
ctcgctgctg cctcagagta agaagagccc ctcaaggttg tcgcctgctc agggccctcc    840
tcaacctcag agctcggcca agaaagagtc cttcggtggt cagggcacca agggaaagga    900
cccgacgtcc ggagccaagg atgggaagag cctcctcagc gggctggcca ctggggagtc    960
cggttggtca cagcaccggc agcggcgcct gcaggaccat ggcaaggaga ggaaggagct   1020
tttctccaca accacttccc agtgtgcana gaagaaacca gaagccagtg gcccagaggc   1080
tgagccctgc ccagagctcc acacggagcc agtggagcca ctgactcggg catcctcggc   1140
aggccctgag ggtggaggag tccgccccga gcagcccttt attgtgctgg gacaggagga   1200
gtacggggaa caccactcat ccatcatgca ctgcagagtg gattgctctg ggaggagagt   1260
cgccagctta gacgtagatg gggtcatcaa agtgtggtcc ttcaacccca tcatgcagac   1320
caaagcatcc tccatttcca aatcaccgct gctgtctttg gaatgggcca ccaaacggga   1380
cagactgctc ttgctgggca gtggtgtggg aacagtgcgt ctctatgaca cggaagccaa   1440
gaagaatctc tgtgaaatca atatcaacga caacatgccc agaatcctgt ctcttgcgtg   1500
cagccccaac gggccttctt tcgtctgttc ggcagcagct ccgagcctca cttcccaggt   1560
ggacttctca gcaccagaca tcggcagcaa gggcatgaac caggttcctg gcaggctgct   1620
gctgtgggac acgaaaacca tgaagcagca gctccagttc tccctggatc cagaacccat   1680
tgctatcaac tgtacagcct tcaatcacaa cgggaacctg ctggtcacag gggcagctga   1740
tggcgtcatc cggctgtttg acatcagcag catnagtgcg cgatgagytg ragggcccac   1800
tacggggagg tctactctgt ggagttcagc tatgatgaga acaccgtgta acagcatcgg   1860
cgaggacggg aagttcatcc agtggaacat ccacaagagt ggccctcaag gtatccgagt   1920
acagcctccc ctncagatgg ccacgggccc ctttgtgctg tctgggataa cagcggctaa   1980
caagca                                                              1986

<210> 961
<211> 583
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (452)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (529)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (537)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<400> 961
tcaattctga ggttatccct caattacctc atcgccaggg ggtggcggat acagtggagc     60
atcgtgcccg aagtgtctga gcccgtggaa cctccaaagg aagacctgac tgtgtctgag    120
aagttccagc tggtgctgga cgtcgcccag aaagcccaga accttttcgg gaagatggct    180
gacatcctgg agaagatcaa gaacttgttc atgtgggtcc agccggagat cacacagaag    240
ctgtatgtgg cgctctgggc tgccttcctg gcctcctgct tcttccccta ccgcctggtg    300
gggcttgccg tgggactcta tgctggtatc aagttcttcc tcattgattt catctttaaa    360
cgctgcccga ggctgcgcgc caagtacgac acgccctata tcatctggag gagtctcccc    420
accgacccgc agctcaagga gcgctccagc gncgcagtct tcacggcagg ctgcagacgg    480
acctcgtcac gggagcttac gtacccagcg gcaccggccg gcctgggtna aagaggnagg    540
gacgccggtt cgttttccac agcaccaaga agggcanttt cca                      583

<210> 962
<211> 1203
<212> DNA
<213> Homo sapiens

<400> 962
gcctggcttt gcctttgccc tgctgtgtga tcttagctcc ctgcccaggc ccacagccat     60
ggccatggcc cagaaactca gccacctcct gccgagtctg cggcaggtca tccaggagcc    120
tcagctatct ctgcagccag agcctgtctt cacggtggat cgagctgagg tgccgccgct    180
cttctggaag ccgtacatct atgcgggcta ccggccgctg catcagacct ggcgcttcta    240
tttccgcacg ctgttccagc agcacaacga ggccgtgaat gtctggaccc acctgctggc    300
ggccctggta ctgctgctgc ggctggccct ctttgtggag accgtggact tctggggaga    360
cccacacgcc ctgcccctct tcatcattgt ccttgcctct ttcacctacc tctccttcag    420
tgccttggct cacctcctgc aggccaagtc tgagttctgg cattacagct tcttcttcct    480
ggactatgtg ggggtggccg tgtaccagtt tggcagtgcc ttggcacact tctactatgc    540
tatcgagccc gcctggcatg cccaggtgca ggctggtttt ctgcccatgg ctgcctttct    600
cgcctggctt ttytgcattg gytcctgcta taacaagtac atycagaaac caggcctgct    660
gggccgacat gccaggaggt gccctycgtc ctggcctacg cactggacat tagtcctgtg    720
gtgcatcgta tcttcgtgtc ctccgacccc accacggatg atccagctct tctctaccac    780
aagtgccagg tggtcttctt tctgctggct gctgccttct tctctacctt catgcccgag    840
cgctggttcc ctggcagctg ccatgtcttc gggcagggcc accaactttt ccacatcttc    900
ttggtgctgt gcasgctggs tcagctggag gctgtggcac tggactatga gcccgacggc    960
ccatytatga gcctctgcac acgcactggc ctcacaactt ttctggcctc ttcctgctca   1020
cggtgggcag cagcatcctc actgcattcc tcctgagcca gctggtacag cgcaaacttg   1080
atcagaagac caagtgaagg gggatggcat ctggtaggga gggaggtata gttgggggac   1140
aggggtctgg gtttggctcc aggtgggaac aaggcctggt aaagttgttt gtgtctggcc   1200
aaa                                                                 1203

<210> 963
<211> 1383
<212> DNA
<213> Homo sapiens

<400> 963
gaataaatac atcatgcaac cccacggccc accttgtgaa ctcctcgtgc ccagggctga     60
tgtgcgtctt ccagggctac tcatccaaag gcctaatcca acgttctgtc ttcaatctgc    120
aaatctatgg ggtcctgggg ctcttctgga cccttaactg ggtactggcc ctgggccaat    180
gcgtcctcgc tggagccttt gcctccttct actgggcctt ccacaagccc caggacatcc    240
ctaccttccc cttaatctct gccttcatcc gcacactccg ttaccacact gggtcattgg    300
catttggagc cctcatcctg acccttgtgc agatagcccg ggtcatcttg gagtatattg    360
accacaagct cagaggagtg cagaaccctg tagcccgctg catcatgtgc tgtttcaagt    420
gctgcctctg gtgtctggaa aaatttatca agttcctaaa ccgcaatgca tacatcatga    480
tcgccatcta cgggaagaat ttctgtgtct cagccaaaaa tgcgttcatg ctactcatgc    540
gaaacattgt cagggtggtc gtcctggaca aagtcacaga cctgctgctg ttctttggga    600
agctgctggt ggtcggaggc gtgggggtcc tgtccttctt ttttttctcc ggtcgcatcc    660
cggggctggg taaagacttt aagagccccc acctcaacta ttactggctg cccatcatga    720
cctccatcct gggggcctat gtcatcgcca gcggcttctt cagcgttttc ggcatgtgtg    780
tggacacgct cttcctctgc ttcctggaag acctggagcg gaacaacggc tccctggacc    840
ggccctacta catgtccaag agccttctaa agattctggg caagaagaac gaggcgcccc    900
cggacaacaa gaagaggaag aagtgacagc tccggccctg atccaggact gcaccccacc    960
cccaccgtcc agccatccaa cctcacttcg ccttacaggt ctccattttg tggtaaaaaa   1020
aggttttagg ccaggcgccg tggctcacgc ctgtaatcca acactttgag aggctgaggc   1080
gggcggatca cctgagtcag gagttcgaga ccagcctggc caacatggtg aaacctccgt   1140
ctctattaaa aatacaaaaa ttagccgaga gtggtggcat gcacctgtca tcccagctac   1200
tcgggaggct gaggcaggag aatcgcttga acccgggagg cagaggttgc agtgagccga   1260
gatcgcgcca ctgcactcca acctgggtga cagactctgt ctccaaaaca aaacaaacaa   1320
acaaaaagat tttattaaag atattttgtt aactcaaaaa aaaaaaaaaa aaaaaaactc   1380
gag                                                                 1383

<210> 964
<211> 611
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (585)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (602)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<400> 964
ggcagcggct agatatggcg tcctctttgc ttgcgggcga gcgattggtg cgtgctttgg     60
gccccggcgg ggagctggag ccagagcggc taccccgaaa gctgcgggcc gagcttgagg    120
ccgcgctggg gaagaagcac aagggcggtg atagctccag tggcccccaa cgcttggttt    180
ctttccgtct catccgggat ctgcaccagc atctgagaga aagggattcc aaactatacc    240
tccatgagct cctagaaggc agtgaaatct atctcccaga ggttgtgaag cctccacgga    300
acccagaact agttgcccgg ctggagaaga ttaagataca gctggccaat gaggaatata    360
aacggatcac ccgcaacgtc acttgtcagg atacaagaca tggtgggact ctcagcgacc    420
tgggaaagca agtgagatca ttgaaggctc tggtcatcac catyttcawt ttcattgttc    480
acggtggttg ctgccttcgt ctgcayttac cttggaagcc attatcttac agaaatggct    540
cgggtgtact gaatgacgcg ctctgggggg gctggccact tatgnatggg cggcaaggaa    600
nnactggaan c                                                         611

<210> 965
<211> 2683
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (43)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (65)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (85)
<223> n equals a,t,g, or c

<400> 965
atgatgttcc atttactngg ttcaccaaaa accaccgact aangttcctt taacccatgg     60
cgggnaacat tctggcgctg gaaangatca acgaacattc tgcacctgca aattagctgg    120
ggtggatggg cgctggcagc cggattgccg ggcatcatta tgctgctggt caccccgctg    180
gtgatttaca ccatgtatcc accagaaatt aagaaggtgg ataacaaaac catcgctaaa    240
gcgggccttg ccgaactagg accgatgaaa atccgcgaaa aaatgctgct cggtgtcttt    300
gtgctggcgc tgctgggctg gattttcagt aagtctctgg gggttgatga atccaccgtg    360
gcaatcgttg ttatggcaac catgctgctg ctgggtatcg ttacctggga agacgtggtt    420
aaaaataaag gcggctggaa taccttaatc tggtacggcg gtattatcgg cttaagctcc    480
ttattatcga aagttaaatt cttcgaatgg ttagctgaag tctttaaaaa taacctggca    540
tttgatggtc acggtaacgt tgactttctt cgttattatt ttcctcagca ttatcgtgcg    600
ttatttcttc gcttccggta gtgcctatat cgttgctatg ttaccggtat ttgccatgct    660
ggcgaacgtc tccggcgcac cgttaatgtt aaccgcgctg gcactgttgt tctccaactc    720
ctatggcggc atggttactc actatggcgg cgcggcaggt ccggtcatct ttggcgtggg    780
ttataacgat attaaatcct ggtggttggt cggtgcggta ctgacgatat taaccttcct    840
ggtgcatatc accctcggcg tgtggtggtg gaatatgctg atcggctgga acatgctgta    900
aatattctcg tcatacttca agttgcatgt gctgcgtctg cgttcgctca ccccagtcac    960
ttacttatgt aagctcctgg ggattcactc gcttgtcgcc ttcctgcaac tcgaattatt   1020
tagagtatat ccatttatta tctttctgcg cacttcacgg tgcgcagata tctggagcat   1080
ttgatgatca agttatctga aaaaggcgtg tttctcgcca gtaataacga aataattgcc   1140
gaagaacatt tcaccggcga aattaaaaaa gaagaagcca aaaaaggcac tattgcctgg   1200
tctattctct cttcgcataa tacgtccgga aatatggata aacttaaaat taagtttgat   1260
tcattagcct ctcacgatat tacctttgtt ggtattgtac agaccgctaa agcgtccggt   1320
atggaacgtt tcccgctgcc gtatgtgctg accaactgcc ataactcact ctgcgccgtc   1380
ggcggcacta ttaacggtga tgaccatgtt tttggtttat cggcggccca gcgttatggc   1440
ggtatttttg tgcctccgca tattgcggtc atccatcaat atatgcgtga gatgatggca   1500
ggcggcggca aaatgatcct cgggtcagac agccacaccc gttacggtgc attagggaca   1560
atggcagtcg gtgagggcgg cggtgagttg gtaaaacagc tgcttaatga cacctgggat   1620
atcgactatc cgggcgtggt tgcggtgcat ctgaccggaa aacctgcgcc gtatgtgggg   1680
ccacaggatg tggcgctggc tatcattggc gcggtgttca aaaacggtta cgtcaaaaac   1740
aaagtcatgg agttcgttgg accgggcgtt agcgcgctct ctaccgattt ccgtaacagc   1800
gttgacgtga tgaccactga aacgacctgt ttaagttctg tctggcaaac cgatgaagaa   1860
gtccataact ggctggcgct gcacggtcgc ggccaggatt actgccagct taaccctcaa   1920
ccgatggcgt actacgatgg ctgcatcagc gttgatttaa gcgccatcaa accaatgatt   1980
gcgctgccgt tccacccgag caacgtgtat gaaatcgaca cactgaacca gaacctgacc   2040
gacattctgc gtgagattga aattgagtcc gaacgcgtgg cgcacggtaa agccaaactc   2100
tcgctgctgg ataaagtgga aaatggtcgc ctgaaagtgc agcaggggat tatcgcgggc   2160
tgttctggcg gtaactacga aaacgtcatc gcggcggcga atgcactgcg cggtcaatcc   2220
tgtggcaatg acaccttctc gctggcagtt tacccgtcat cacagccggt gtttatggat   2280
ctcgccaaaa aaggtgtggt agcagatttg attggcgcag gcgcaatcat cagaaccgcg   2340
ttctgcggcc catgctttgg cgcgggcgat acgccaatca acaacggttt gagtattcgc   2400
cacaccacgc gtaacttccc gaaccgcgaa ggctctaagc cagctaatgg gcagatgtca   2460
gcggtggcgt tgatggacgc tcgttctatc gctgcgactg cggcaaacgg tggctattta   2520
acctctgcca gcgaacttga ttgctgggac aacgtgccgg agtacgcctt cgatgtaacg   2580
ccgtataaaa accgtgttta tcagggcttt gtgaaagggg caactcagca accgctgatt   2640
tacggggggg cccggtaccc aattcgccct atagtgagtc gta                     2683

<210> 966
<211> 803
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (360)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (367)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (774)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (784)
<223> n equals a,t,g, or c

<400> 966
aattcggcac agtttagttc gaatatcact gtgaaatata tagagaagag gctctggggg     60
ctcatgaact tggcccatgg actgttgagg cttttttttt aatctttaga gatgatataa    120
atgtagtgct ttggaattcy ttatawttar aagttttatt cttaccccat caccatgtcc    180
caagataatt tttattatca tctttcagct ttaacatatc acagacaaaa gttatttttc    240
caaatagawt tttaagtatg gtataagagg tttttagaaa tggaatgatt ggttttggcg    300
gaactgcctg gcctgacctg tcactcgggt gaagtgtcag agagctgtgt cgaatgctgn    360
cggaganctg tccctctcct gcagagagaa ggagctgctt atcctggggg ataatgtggg    420
ttgagaaaga agtgttttat gagcagaatc agcacagagg gagggaggag gaggtgttta    480
ggggctgcag agagccgcca gaagatgtgg gaacagtatg ccagcacgga ggtgggtcar    540
atccccatgg tgggactctg ctgagggttg cctccagccg agacttccaa gggctgggat    600
tcagtgtgtg tttatgttct ctggtgtgcc tgataggtgg gggcccacat gacagctggc    660
ctctctgtgt ttcccttctg gccgtctctg atttggggcc caagggccat aggggggcca    720
gggcactcca gatgggacga aaatcaagtc caagaaaaaa aaaaaaaaaa aacntggggg    780
gtanttttgg gggggcccgg ggg                                            803

<210> 967
<211> 684
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (635)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (646)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (678)
<223> n equals a,t,g, or c

<400> 967
ggtgaggctc accatgaaag ctcaggactg caggcgtgga gctgtgcatg gctctaggac     60
gcgcctttgc cccctgggcg agggtgtcct ttctcacgag gtgcccatcc gtcacccccg    120
tggcccatat caccccttcc tctctgaggg agtcttcggt gcgtgggggc ggcttgctgt    180
ccagcctgtg tgggggccgt cccgtcccac actcccctgg gcattcttgg actcaaggcc    240
ggggctctgc gtggcttgct gggaggtggg ctgcagcaca gaggcctgtg actgcgttcc    300
agcggccagt tcactacgca tatctctggg gcctgggacc agccacgtgc cgagctgtca    360
gcgacgtgag gtgtcccttc tcgktgagat atttaacttt ggttttgctc tagttctttc    420
tttttgaaga gagtgactgg agtggtaaag atggaaatgc tggaaatgat actggcgctc    480
acgctgccat ccgaccamcc tcggctcccg agtccacgcc tgcctgggsc tgkgctgkca    540
gaccgcgtcg gtcgtaacct ctgtgggtcc ctgcatcaga acgtccaaca acaagtcacc    600
aagttcacca gaaagggttc aaaatagcaa accanactga gtgttntnat ggtggaattg    660
acatctggaa acctgaanaa aaga                                           684

<210> 968
<211> 1603
<212> DNA
<213> Homo sapiens

<400> 968
tcgacccacg cgtccgctct gccaggaatc tggtctttct gtagacccaa gtcagaaaga     60
accatttgtg gagttaaatc gaatattaga rgcattaaar gtcagagttc tgagacctgc    120
tctggaatgg gcagtttcaa accgagagat gcttatagcc caaaacagct ccttggaatt    180
taaactacac agactgtatt ttattagctt rttaatgggt ggaacacaaa tcagcgagar    240
gcattacaat atgctaaaaa ttttcagcca tttgccctaa atcatcaaaa agacattcag    300
gttttgatgg gaagccttgt gtacctgaga caagggattg agaactcacc atatgttcac    360
ctacttgatg caaaccagtg ggctgatatc tgtgacatct ttacacggga tgcttgtgcc    420
ctcctggggc tctccgtgga gtcccctctc agtgtcagtt tctcagcagg ttgtgtggcg    480
ctgccagctt taattaacat caaagccgtg attgaacaga ggcagtgtac tggagtttgg    540
aaccagaaag atgaattacc tattgaagtg gaccttggta aaaagtgctg gtatcactct    600
atatttgcct gccccattct tcgtcagcaa acaacagata acaatccacc catgaaattg    660
gtctgtggtc atattatatc aagagatgcc ctgaataaaa tgtttaatgg tagcaaatta    720
aaatgtccct actgtccaat ggaacaaagt ccaggagatg ccaaacagat atttttctga    780
agagataact ttagtttgca atttgtaagt gaaactgaat cgtgggtgca tttcagaaga    840
gaacgttcca tataatgcag ctaaccaagg actcctgtgt ttctataagc taatgctcca    900
gaaactttgc caacctgtta gtgtacacac actgagggga gtgctcccgg tgaatattat    960
catagggctt tattatattc ttggtcttca tttctgatca agtaaataca ccagcagttg   1020
tcattcaatg caggtttttg tacttaatta tatggtgatt tttttacttt ttaagagcag   1080
aaacggaaat tgacctcccc gccatgtgtt taatattcct cctgctttta cttttgtcat   1140
tttcttgata atcgtaagcc ttgagagtgt ttgtgaaaaa gttttatttc ctgttatgta   1200
tacataatta aatgaaaatt cttcagaaaa agtttgataa attgaattgt ggttatgaaa   1260
ctaatttgca tttttatttg cttaagaaag aaagctgtga tagattccag atatgctttt   1320
tgatgttttc ctctgctcca gctccaagaa gtcagcacac ctgcatttta gctctgcatg   1380
cagccccagc aggctgcgtg tttaagaatt tcattgttta actggctggt gtgagaagtc   1440
ttccgttagc atagagtgga aggagtacta ttgtttggtt gggtttttgt ttgtttgttt   1500
tttgtttttg cttttattgc caagaggtgc ttgttttaaa agtatgttta ataaaatgaa   1560
attctaaagt taaaaagtgt tcttaaagtt gatatttaac tct                     1603

<210> 969
<211> 684
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (650)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (663)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (668)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<400> 969
gacggatcac cctccgctcc aacatggcta gtcctcaacg cgtgactcaa gcctgttgtg     60
ccagcaggcg cactcagcag cgaccctcat aggtggcgaa ggtccgcgag agggttccgc    120
cagctagaca gtggagtgcc gcacagcgcg ccttccagcc tcgcagccgc caccctagcg    180
gttccgaccc ggcgccacag gcctgcttgg tcgatcttcg agccaaagat gcggcgaggc    240
tggaagatgg ctctgtctgg ggggctgcgg tgctgccgcc gggtactgtc ctgggtgcca    300
gtgctcgtta ttgtcctcgt cgtgctctgg tcctactatg cctacgtctt tgaactctgc    360
ctggtgactg ttttgagccc agcagaaaaa gttatttacc tcatactcta ccatgccatc    420
tttgtgttct ttacctggac ctactggaag tctatcttta cactcccaca gcagccaaac    480
cagaagttcc acttgtccta cacagacaag gagcgctatg aaaatgaaga aagacctgag    540
gtccagaagc agatgcttgk tgatatggcc aaaaagctac cggtttacac aagaactgga    600
agtggagctg acgawtctgt gaccsgtgtc atctgatcaa gccagaccgn tggcaccaat    660
tgntctgnct ggggctatgn ggtg                                           684

<210> 970
<211> 775
<212> DNA
<213> Homo sapiens

<400> 970
atgcgccgaa agatgacatc atcgtcatgc tgctgtgcat gtcgctgacc gtgttgtttg     60
atatggttat tgccatcagc gtggggatcg tgctggcatc gctgctgttt atgcgtcgta    120
tcgcacgtat gactcgcctg gcaccggtag tcgtagatgt tccagacgat gtcctggttc    180
tgcgcgttat tggcccgctg ttttttgctg ctgctgaagg cttattcacg gacctggagt    240
cacgtcttga aggcaaacgg attgtgattc tgaagtggga tgccgttccg gtacttgatg    300
ctggtggtct tgatgcgttc cagcgttttg tgaagcgtct gcccgaggga tgtgaactgc    360
gcgtgtgcaa gtggaattcc agccactgcg cactatggct cgcgctggca ttcaaccgat    420
cccgggacgc ctggcgttct tcccgaatcg tcgcgcggcg awggcggatt tataagtacg    480
agattgacca gtcagcgcaa actgactggt cagcaaactg cattatttgt tagctatgac    540
ggcgattatc gctacggcgg caacgtttgt catagtggcg aacccaccag taacggtcgc    600
acacctgttc atgcccgcca acacgggcac ccgccagcca gagaatggca ccgacgaaaa    660
tacttagcac tgcaccatgt gcgaaatact ggggcataat taaactgtgg taactggttg    720
aagattgaat acccacgccg accaccatta caccagaccc aaccccatga acacg         775

<210> 971
<211> 1399
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (38)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (747)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1378)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1392)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1398)
<223> n equals a,t,g, or c

<400> 971
cggtagtccc cgnaaccaac aagtgcggca ttttcgcnag atcggcaacc accggctcac     60
cggcgatatc tttacccagc accacggtta atggcgacgg attatcgcgg aatttggcgt    120
tatccaaaac ttcgcgcaga taaacggttt gtcgtttttt attcggtaac tccagaccta    180
catagggttt gccaggaata acttcaacga cacgcaccgc caccgtcgaa agtgaacggg    240
caaggtcccg tgacaagtta gaaatgcgcg ccgcttttac gcccggtgcc aggttcaatt    300
caaagcgagt gataaccggc cccggagagt aattgacgac atcggcttta atacggaaat    360
cagccagacg cgcttccacc aggcgagcca tttgttcaag cgcaaaggta tctaccggct    420
ccacttcgct cggcggcggt gtcagcaaat ccagagaagg cagcggcgtc gtcggtttat    480
gcaacggacg gctgtcgcca ttacgcatca acagcggatg aagcagggta tcctgcggtt    540
gtggcgcaac tggctgttgt ggctgctgat actgctgctg cggcgcaacc ggttgttgcg    600
gctgctgata ttgctgctgt ggcgcaaccg gttgttgcgg ctgctgatat tgtggctgcg    660
gcgcaaccgg ctgttgtggc tgctgatact gcggctgcgg cggaactggt tgttgcggct    720
gctgatattg ctgctgcggt gcaacgnttg ttgcggctgc tgtacaggtt caacaattgg    780
cgtaaacaac ggttcgtgtg gaccatcatc cagcaacgct ttcattggcg aaaattcaaa    840
atcatccagc gagaacggat tcgccccagc cggttgttcg ccggaataac gttgttgttg    900
agtttgcgca aactgacgag ccagttcagc ctctgccgca gcatctgcat cttctgcgtt    960
tacgggcaca tcatgttgat actgttcgcc atagcgttgc tgctgtgtct gggcgaactg   1020
acgtgccagt tcatcctgct gcatcgcatc gatttcatca tcgttgtact gatcgccaga   1080
atcgtactga ttgcgctggg cttcacgggc tttttcttcc gccgcacgct gtgagggcag   1140
cttaataccg taagacgcca gttcacgacg agttggcacg cggatacgtt tcggtcgtgg   1200
caactgcgga ccaatcccct ctttgacctg aggacgcggt ccaccgctat ttgccagact   1260
gaagactggc gcggcaacgg ttgcggcagc ccccgtcgcc agtgtcgctt ttttcacgcc   1320
agatgccagc gagtcactca gcgcactggt taaggcgggg gcccggtamc caattcgncc   1380
tatagtaatc gngttacna                                                1399

<210> 972
<211> 437
<212> DNA
<213> Homo sapiens

<400> 972
acaagggaac tgggaccgtt gggctgaaac agtcttgagc ctggggttga ctgggttaga     60
gaagaaccgg gatgcaagga gctgcctgtg acacctggcc tgccctttct cagctgcctc    120
ccctgccctt tctcagctgc ctcccctgcc ctcagaagga aaggagaggg ctcacttatc    180
acttgtgcca tagcacctgg tctcaaaatc ctaaaagctt tcctcgccct cactgccttg    240
ctccacaagg tccactttcc tgggtcttgt gctgtgcctt tccttgtctg cctcctgctg    300
cttctgtaac tgcagacccc aggcccaatg gcaagccctc ggctcagctg cttctccatt    360
ggaataaact cttgtttctc tatgtcgatg ttcttctctg gtcttcctcc ctgcctatca    420
agagctgagt gataact                                                   437

<210> 973
<211> 1934
<212> DNA
<213> Homo sapiens

<400> 973
gcctgagttg aaagatcatc ccatcacaca gttttcatta ttggccatgg catccttgac     60
aaaaatactg gtcattggat tgaaaccatc cttgaaagta tggatgactt ttccctatgg    120
ccggatggat ccttccagtg tgccactgct ggcctggcac tttgtagcag tacaaaatta    180
cgtgaatccc atgcttgcct tctgcagagg agatgttgtt cattttctat tggtaaagag    240
agatgaatct ggagcaatac atgttactaa gcaaaagcat cttcacctat actatgacct    300
catcaacttt acctggataa attcacgcac agttgtgctc ttagacagcg tagagaagtt    360
gcatgtgatt gatcggcaaa cacaagagga attggagaca gtggagatct cagaagttca    420
gctggtctac aatagcagcc atttcaaatc actagccact ggaggaaatg ttagccaggc    480
actggctttg gttggagaga aggcttgtta tcaatccatc agtagctatg gtggtcagat    540
cttttatttg gggacaaaat ctgtttatgt gatgatgctg aggagctgga gagagagagt    600
ggatcatctc ctgaaacaag attgtcttac agaagcgttg gctcttgcgt ggtctttcca    660
tgaaggaaaa gcaaaagcag tagtgggatt atcaggggat gccagtaagc gaaaggctat    720
tggtgcagac cggatggtag aaatcctatt ccattatgca gatcgagctc tgaaaaagtg    780
cccagaccaa ggaaaaatcc aagtgatgga gcagcatttt caggatatgg tgcctgtcat    840
agttgattac tgccttctgc tgcagcgaaa ggatctttta tttagtcaga tgtatgataa    900
attaagtgag aattcagtgg ccaaaggagt atttttggag tgccttgagc catatatttt    960
aagtgataaa ttggtgggaa tcacacccca agtaatgaaa gacttgattg ttcatttcca   1020
agataaaaaa ttaatggaaa atgtggaagc gctcattgta catatggata tcaccagcct   1080
agatattcag caggtagttc tcatgtgttg ggaaaatcgt ttatatgatg ctatgatcta   1140
tgtctacaac agaggcatga atgaatttat tagtccaatg gagaaacttt tcagagtcat   1200
tgctcctcct ctgaatgcag gaaaaacact aacagatgaa caagttgtta tgggcaataa   1260
gctccttgta tatattagct gttgtctagc aggtcgtgcc tatccccttg gtgacatccc   1320
tgaagatctg gttcccttgg ttaaaaacca ggtttttgaa tttctaattc gcctgcattc   1380
agcagaggct tctcctgagg aagaaatcta tccttacatt cggactttgc tacattttga   1440
cacaagagaa tttctcaatg tattggcact gacttttgaa gattttaaaa atgacaagca   1500
agctgtggaa tatcaacagc gaattgtgga tattttgttg aaagttatgg tggagaattc   1560
agactttacc ccctcacaag taggatgtct ctttaccttc cttgctcggc agcttgcaaa   1620
gcctgacaac accttgtttg taaacagaac actttttgat caggtccttg aattcctttg   1680
tagtcctgac gatgactccc gacactctga aagacagcag gtccttttag aattgctgca   1740
ggctggaggc atagttcaat ttgaagagag tcgactcatc cggatggcag aaaaagctga   1800
gttctatcaa atttgtgaat ttatgtatga aagagaacac caatatgacc aaaattrttg   1860
rttgccactt acgtgacccc tgcgagagga rgagtcttta attacattca catatcttac   1920
ccaattcccg ggac                                                     1934

<210> 974
<211> 1285
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (576)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1281)
<223> n equals a,t,g, or c

<400> 974
cggataagcg gcggcaccgg cgtcacgatg accgtgcaga gactcgtggc cgcggcgtgc     60
tggtggccct ggtctcactc atcctcaaca acgtggcggc cttcacctcc aactgggtgt    120
gccagacgct ggaggatggg cgcaggcgca gcgtggggct gtggaggtcc tgctggctgg    180
tggacaggac ccggggaggg ccgagccctg gggccagagc cggccaggtg gacgcacatg    240
actgtgaggc gctgggctgg ggctccgagg cagccggctt ccaggagtcc cgaggcaccg    300
tcaaactgca gttcgacatg atgcgcgcct gcaacctggt ggccacrgcc gcgctcaccg    360
caggccagct caccttcctc ctggggctgg tgggcctgcc cctgctgtca cccgacgccc    420
cgtgctggga ggaggccatg gccgctgcat tccaactggc gagttttgtc ctggtcatcg    480
ggctcgtgac tttctacaga attggcccat acaccaacct gtcctggtcc tgctacctga    540
acattggcgc ctgccttctg gccacgctgg cggcancatg ctgcatctgg aacattctcc    600
acaagaggga ggactgcatg gccccccggg tgattgtcat cagccgctcc ctgacagcgc    660
gctttcgccg tgggctggac aatgactacg tggagtcacc atgctgagtc gcccttctca    720
gcgctccatc aacgcacacc tgctatcgtg gaacagccta gaaaccaagg gactccacca    780
ccaagtcact tcccctgctc gtgcagaggc acggggatga gtctgggtga cctctgcgcc    840
atgcgtgcga gacacgtgtg cgtttactgt tatgtcggtc atatgtctgt acgtgtcgtg    900
ggccaacctc gttctgcctc cagctttcct ggttagcgca acgcggctcc acgaccacac    960
gcacttcagg gtggaagctg gaagctgaga cacaggttag gtggcgcgag gctgccctgc   1020
gctccgcttt gctttgggat taatttattc tgcatctgct gagaggggca ccccagccat   1080
atcttacact ttggtaaagc agaaaaccag gaaaattttc ttaaaatatc cacaatattc   1140
cttgagtgag tcagaatcta tagccggtta gtgatggttt cagacagaat cgtgttcgtg   1200
tctgttttgc tcgattcctt tcctaagtta aataaatgca agcctctgaa aaaaaaaaaa   1260
aaaaawaatt cggggggggg ncccc                                         1285

<210> 975
<211> 1445
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (542)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (892)
<223> n equals a,t,g, or c

<400> 975
tcgaggagct cagagtctag tgtgggagat aaatacctaa aagctagtta tggccaagtg     60
tgagaagctt gaggtcagcc caggggccct ggttgcacag gggagggagg gatggactgt    120
ctctgcttca ggataattgg ggaagccttc atgggggagg tgacaatagg caggagcagg    180
aagtcacttc aagtcacaag taagagtatg agcaaggagg agggggtata gctcagaggt    240
agagcattgg gctgcagatt aagaatatga gcaaggmcac atggmcmcaa aatagaaata    300
gcatactcat tgctcattgt gtggggagct ggggagtgat tttattctgc cagcacctct    360
ctttcctgtt catccccctt gccaggtgtt gaatttctca gtagcagaat ccctgtctac    420
ttttacaata tgttctccct ctcttttcct cttttttcca tagtgctttc tatagcacct    480
tgctggaatt tatggatgaa tgaatagttc ttgctgttct aaggttactc tagggatctg    540
gnaaataata aagaccatta ttaagattat taacagcttt cagatgacat ctatcttagt    600
gatcaaggtg caaataaagc tagctgacca agagatgtgg ttgctatgtt gaccaggtga    660
ccaagatggt gactgagatg ccaagtggct aacatgatga tcaacccaaa ttgtctggta    720
aatgcaccac tttctgaaat gcacatttca gggtaggtga aggaaataca tgtacctgac    780
atggcccagt ctgacacgtg tcacctcttc tgtcttctyc ccaggctgct ctgcgtagat    840
tggctggggt ctgccctgaa ggcctccagg actctgactt tyagcagttg gnccagcctc    900
ggctggtgga ctccttctta ctctgcagca acatggagga gagttttgtg tagtgagtgt    960
gggmgaagaa atacatttgg ctgttctcac accccctctg actatgcacc agtgaacaca   1020
tctgagtaca taccagctct cctcatcttc ttatttatac ttaacttatt tttgtgtgaa   1080
ataaatggag gacgaaatct tagagcaaca tcatcaaaca gtctttggtc cttgagaatc   1140
ttctttgtgt tttatttttt gatttctgta gcttttcagt tgcagatgtt gaaattcgta   1200
atgacaaata tgacaaattg tcatgggtga ttccacttca tcttattttt tctactctca   1260
ctatacaatc ttgcctcatt ttttaaaact ttggaaccag aggatttcaa ctgcctagca   1320
agtttttttt ttaagttgga tttgctcttc ccaaaaatct aaaatgaatt taataattgg   1380
gtagaatata ttggaaagaa gtttcttttt ctttaataaa tggaatcata taaaatgaaa   1440
aaaaa                                                               1445

<210> 976
<211> 1694
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (328)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1553)
<223> n equals a,t,g, or c

<400> 976
tgccggagaa agtccgcgaa gtgttgcaac agtttgacga tcaawgcgcc accagcgtac     60
ccgtcagata aaatccgtct gattgtccag gcgattattg gcgtctggct ggtgactgcg    120
ctggcgttgc atctggcgga agttggcttg attggtttgt cagtcattat tctggcaaca    180
tcattgaccg gtgtcaccga tgagcatgct atcggtaaag ccttcaccga atctytgcca    240
ttcaccgcac tgttgasggt gtttttytcg gtagtcgcgg tgattatcga ccaacaactg    300
ttttcgccaa ttattcagtt tgtgttgnag gcatcggaac atgctcagct gtcgctgttc    360
tatattttca acggtctgct gtcatccatt tcggataacg tcttcgtggg gacgatttat    420
atcaacgaag cgaaagsggc aatggaaagt ggcgctatca cgttgaagca atacgagctg    480
ctggcggtcg ccattaatac cggtaccaat ctgccctccg tcgctacgcc gaacggtcag    540
gctgcgttcc tgttcctgct gacctctgca ctcgcgccat tgattcgcct ctcttatggc    600
cgcatggtgt ggatggccct gcctwacacc ctcgtcctga cactcgtcgg cttgctctgc    660
gtcgagttta cgcttgcccc tgtaaccgaa tggtttatgc aaatgggctg gatagcaacg    720
ctttgataac aacttaccgg gcatataaat gcccggtttg ccttttcgcc cgataattgt    780
ccaattgcgt cctatttttg ctgcctcctg gtggcgcagc gaatgaattg gtttaaactg    840
cgcactctat gcatattgca gggaaatgat tatgttgcga tttttgaacc aatgttcaca    900
aggccggggc gcgtggctgt tgatggcgtt tactgctctg gcactggaac tgacggcgct    960
gtggttccag catgtgatgt tactgaaacc ttgcgtgctc tgtatttatg aacgctgcgc   1020
gttattcggc gttctgggtg ctgcgctgat tggcgcgatc gccccgaaaa ctccgctgcg   1080
ttatgtagcg atggttatct ggttgtatag tgcgttccgc ggtgtgcagt taacttacga   1140
gcacaccatg cttcagctct atccttcgcc gtttgccacc tgtgatttta tggttcgttt   1200
cccggaatgg ctgccgctgg ataagtgggt gccgcaagtg tttgtcgcct ctggcgattg   1260
cgccgakcgt cagtgggatt ttttaggtct ggaaatgccg cagtggctgc tcggtatttt   1320
tatcgcttac ctgattgtcg cagtgctggt ggtgatttcc cagccgttta aagcgmmaaa   1380
mcstgatctg ttcggtcgct aatccattcg gcgctcctgc gggagcgctt ttttcctgcc   1440
gctatattta tttgaccctc agtaaatcag aacttcgcgt tgtataacgt ggtgaaagca   1500
tggctcgctt catctgccat tgttgctgga tcccctgccc ggcaaaatag agngttcctc   1560
tgccctcttt agcattcagt gtatccatta ccgtcatcaa ttgctcactc ccggggcgcg   1620
gtgcgttgtc atcgaataaa ttgagctgcg cgactccctg actgaagaaa tcccccagca   1680
tcacgcccgc tctt                                                     1694

<210> 977
<211> 782
<212> DNA
<213> Homo sapiens

<400> 977
gagatcaacc tcttcaacca ctgggtgtca gggctggccc aggaggcccg ggggtcctgt     60
aactggcagg cccacctacc cctgggagct gcagcctgcc ccctgsgcag gctctccggg    120
ctgggctggc tctgatacag gtccccgtat ggctggtgct acagggaccc aggctgatgt    180
gggctggcat gtggggcagc accaagggcc tgggcctggc cttgctcagt gcctgggagc    240
agctgggcct gtctgtggcc atctggacag atctgttttt gtcatgtctg cacggcctga    300
tgttggtggc cttgctcttg gtggtagtga cctggagggt gtgtcagaag tcccactgct    360
tccgactggg caggcagctc agtaaggcct tgcaagtgaa ctgcgtggta aggaagctcc    420
tggtacagct gagacgtctg tattggtggg tggagactat gactgccctc acctcctggc    480
acctggccta tctcatcact tggaccacct gcctggcctc ccacctgctg caggctgcct    540
ttgagcacac gacccagctg ccgaggccca ggaggttgaa ccccaggagg tctcagggtc    600
ttccttgctg ccctcactgt ctgcgtcctc ggactcagag tctggaacag ttttgccaga    660
gcaagaaact cccagagaat aaatgtatcc ccatctgcaa aaaaaaaaaa aaaaaaaaaa    720
aaaaaaaaaa aaaaaaamaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaactcg    780
ag                                                                   782

<210> 978
<211> 1671
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (918)
<223> n equals a,t,g, or c

<400> 978
gtacctggat atccacgcct tcatcaggtt gcagacggat agtcagttta ttctgcggca     60
gatcctgcca cgattcttta aacagattca gttcaggtgt tttgaaatag accacgactt    120
cagaacattt ggtcggcaga cgtttaccag tacgcaggta gaatggcaca ccggcccagc    180
gccagttatc aatgtcgacg cggatcgcca cgaaagtttc tgtattgctg ctcttgttcg    240
cgccctcttc ttccagatat cccggcactt ttttgccctg ggcgaacgca gtatattgcc    300
cgcgtacggt tttttcgcgt acgttggagc ggtcgatgcg gcgcagagac ttcagtactt    360
tcactttttc atcgcggatg ctgtctgcgc tcaggtcaga cggcggagac atcgcaatca    420
tgcaaagaat ttgcagcagg tggttctgga tcatgtcgcg catctgaccg gctttatcaa    480
aatagcccca gcgcccttcg atccccactt cttctgccac ggtaatctca acatgatcaa    540
tggtgcgatt gtcccagtta ttcacaaaca gggagttagc aaaacgcagc gccaacaggt    600
tcagcaccgt ttctttacca agatagtggt cgatacggta aacctggcac tcctcgaagt    660
attcgccaac ctgatcattg atttcctgcg argtcgccag cgacgtcccc agcggtttct    720
ccatgamtam gcgtgccggt ttagcattca gttttgcctc gccaagccct ttgcaaattg    780
cgccaaaagt gctgggcggc atggcaaagt agttaatggt gatacgattt ttttgatcca    840
gcatcgcgcc gagacggctg aatgcagcag tgtcattgac atcgagatta caaaaatcca    900
gacgtgcact cagggtgncc cataaacctt catcaatggt ttctttcatg aaagtttcga    960
gcgcctcgcg gacaactttg gtatatgccg ctttatccca gcagcacgcc ctacgccgat   1020
aatmcggstg tccgggttga gctgaccggc tttttccagw tgatacaggg aaggcagyaa   1080
tcacccaccg taaacaggcc gcttgaggga aataagacga tgccgcttta cccagtttaa   1140
cctgcacttt attctcaacg acttgcctgt attggctccc ttttaatcac tttgcgtcgg   1200
gaagttatgc tggaaaattt gaatctctct ctattctctc ttattaacgc gacgccagac   1260
tcggctccgt ggatgatctc gttggcgatt tttattgcta aagatttgat taccgtggtg   1320
ccgttgctgg ccgtggtact ttggttgtgg gggcttacag cacaacggca actggtgata   1380
aaaatcgcta tcgcgctggc ggtcagcctg tttgtgtcct ggacgatggg acatcttttt   1440
ccgcacgacc gaccctttgt cgaaaatatc ggctataact tcctgcatca tgcggcggat   1500
gactcattcc caagcgatca cggtacggtg attttcacct ttgcactggc atttttatgc   1560
tggcatcgcc tgtggtccgg ctcactttta atggtgctgg ccgtcgtcat tgcctggtcg   1620
cgcgtttatc ttggcgtcca gtacccaatt cgccctatag tagcgactca a            1671

<210> 979
<211> 3113
<212> DNA
<213> Homo sapiens

<400> 979
gttattaatg accgctgagc aggcagcacc atgtcagtgt gacaactgaa tcgggtgaac     60
gatgcaccac taaccaccat ggaaacaagg aaaaataaag ccagctcaca ggatctctct    120
tcactggatt gagagcctca gcctgccgac tgagaaaaag agttccagga aaaagaagga    180
atcccggctg cagcctcctg ccttccttta tattttaaaa tagagagata agattgcgtg    240
catgtgtgca tatctatagt atatattttg tacactttgt tacacagaca cacaaatgca    300
cctatttata ccgggcaaga acacaaccat gtgattatct caaccaagga actgaggaat    360
ccagcacgca aggacatcgg aggtgggcta gcactgaaac tgcttttcaa gcatcatgct    420
gctattcctg caaatactga agaagcatgg gatttaaata ttttacttct aaataaatga    480
attactcaat ctcctatgac catctataca tactccacct tcaaaaagta catcaatatt    540
atatcattaa ggaaatagta accttctctt ctccaatatg catgacattt ttggacaatg    600
caattgtggc actggcactt atttcagtga agaaaaactt tgtggttcta tggcattcat    660
catttgacaa atgcaagcat cttccttatc aatcagctcc tattgaactt actagcactg    720
actgtggaat ccttaagggc ccattacatt tctgaagaag aaagctaaga tgaaggacat    780
gccactccga attcatgtgc tacttggcct agctatcact acactagtac aagctgtaga    840
taaaaaagtg gattgtccac ggttatgtac gtgtgaaatc aggccttggt ttacacccag    900
atccatttat atggaagcat ctacagtgga ttgtaatgat ttaggtcttt taactttccc    960
agccagattg ccagctaaca cacagattct tctcctacag actaacaata ttgcaaaaat   1020
tgaatactcc acagactttc cagtaaacct tactggcctg gatttatctc aaaacaattt   1080
atcttcagtc accaatatta atgtaaaaaa gatgcctcag ctcctttctg tgtacctaga   1140
ggaaaacaaa cttactgaac tgcctgaaaa atgtctgtcc gaactgagca acttacaaga   1200
actctatatt aatcacaact tgctttctac aatttcacct ggagccttta ttggcctaca   1260
taatcttctt cgacttcatc tcaattcaaa tagattgcag atgatcaaca gtaagtggtt   1320
tgatgctctt ccaaatctag agattctgat gattggggaa aatccaatta tcagaatcaa   1380
agacatgaac tttaagcctc ttatcaatct tcgcagcctg gttatagctg gtataaacct   1440
cacagaaata ccagataacg ccttggttgg actggaaaac ttagaaagca tctcttttta   1500
cgataacagg cttattaaag taccccatgt tgctcttcaa aaagttgtaa atctcaaatt   1560
tttggatcta aataaaaatc ctattaatag aatacgaagg ggtgatttta gcaatatgct   1620
acacttaaaa gagttgggga taaataatat gcctgagctg atttccatcg atagtcttgc   1680
tgtggataac ctgccagatt taagaaaaat agaagctact aacaacccta gattgtctta   1740
cattcacccc aatgcatttt tcagactccc caagctggaa tcactcatgc tgaacagcaa   1800
tgctctcagt gccctgtacc atggtaccat tgagtctctg ccaaacctca aggaaatcag   1860
catacacagt aaccccatca ggtgtgactg tgtcatccgt tggatgaaca tgaacaaaac   1920
caacattcga ttcatggagc cagattcact gttttgcgtg gacccacctg aattccaagg   1980
tcagaatgtt cggcaagtgc atttcaggga catgatggaa atttgtctcc ctcttatagc   2040
tcctgagagc tttccttcta atctaaatgt agaagctggg agctatgttt cctttcactg   2100
tagagctact gcagaaccac agcctgaaat ctactggata acaccttctg gtcaaaaact   2160
cttgcctaat accctgacag acaagttcta tgtccattct gagggaacac tagatataaa   2220
tggcgtaact cccaaagaag ggggtttata tacttgtata gcaactaacc tagttggcgc   2280
tgacttgaag tctgttatga tcaaagtgga tggatctttt ccacaagata acaatggctc   2340
tttgaatatt aaaataagag atattcaggc caattcagtt ttggtgtcct ggaaagcaag   2400
ttctaaaatt ctcaaatcta gtgttaaatg gacagccttt gtcaagactg aaaattctca   2460
tgctgcgcaa agtgctcgaa taccatctga tgtcaaggta tataatctta ctcatctgaa   2520
tccatcaact gagtataaaa tttgtattga tattcccacc atctatcaga aaaacagaaa   2580
aaaatgtgta aatgtcacca ccaaaggttt gcaccctgat caaaaagagt atgaaaagaa   2640
taataccaca acacttatgg cctgtcttgg aggccttctg gggattattg gtgtgatatg   2700
tcttatcagc tgcctctctc cagaaatgaa ctgtgatggt ggacacagct atgtgaggaa   2760
ttacttacag aaaccaacct ttgcattagg tgagctttat cctcctctga taaatctctg   2820
ggaagcagga aaagaaaaaa gtacatcact gaaagtaaaa gcaactgtta taggtttacc   2880
aacaaatatg tcctaaaaac caccaaggaa acctactcca aaaatgaaca aaaaaaaaaa   2940
aagcgaaaga ctgcagttgt gctaaaaaca aaacaaaaca aacaaacaaa caaaaaagta   3000
aaaaaagatt actttcgaga gagaagttta agcttcacca atggctggct cctggaccaa   3060
tgggaaatat gttacaactt tcaggcattt tttaagtgaa cttttttttt ttt          3113

<210> 980
<211> 1720
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<400> 980
caggcggcgg cggccggggc tcgagccgna ggcaggagca gccgccatgg ccgagagcat     60
cataattcgt gtccagtccc crgatggagt gaagcgratc acagcaacaa agagagaaac    120
agcagcaaca tttttgaaaa aggttgcaaa ggagtttggc ttccaaaata atggcttctc    180
ggtttacatc aatagaaaca agaccggaga gataacagcc tmctccaaca aatccctcaa    240
cttgctaaaa atcaagcatg gcgatttgtt gttcctgttt ccctcgagcc ttgctgggcc    300
ctcatctgaa atggagacgt cagttccacc gggcttcaaa gtctttggcg ctcccaacgt    360
ggtggaggat gagattgatc agtacctcag caaacaggac gggaagattt acagaagccg    420
agacccacag ctatgccgcc acggcccttt ggggaaatgc gtgcactgcg tccctctaga    480
gggggaagtt tgttgccctg gagaacatca gctgcaagat taagtcaggg tgcgaggggc    540
actcccgtgg ccgaatgact ctgtactaag tgccagccga gcgccatcac gctgaacaga    600
cagaagtaca ggcatgtgga caatatcatg tttgagaatc acaccgtcgc tgaccgcttt    660
cttgacttct ggagaaagac agggaaccag cattttgggt acttatacgg acggtacacg    720
gagcacaaag acattcccct tggcatcagg gctgaagtgg ctgcgattta tgagccacct    780
cagattggta cacagaacag cttggagctt cttgaggatc caaaagctga agtggtcgat    840
gaaattgctg ccaaacttgg cctgcggaag gttggctgga tatttacaga cctcgtctca    900
gaagataccc gaaagggtac cgtccgctac agtcgaaata aggacaccta tttcctaagt    960
tcagaagagt gcatcactgc aggagacttc cagaacaagc atcccaacat gtgccggctc   1020
tctccagacg gacattttgg atccaagttt gttactgcag tggctacagg tggtcctgac   1080
aaccaagtcc actttgaagg gtaccaggtg tccaatcagt gtatggcact ggtccgtgat   1140
gagtgtttgc tgccatgcaa ggacgccccg gagctgctac gccaaggagt ctagcagtga   1200
gcrgtacgtg cctgatgtgt tttataagga cgtagacaag tttggcaacg agatcaccca   1260
gctggcccgg cccctgcctg tggagtatct catcatagac atcacaacaa ctttccccaa   1320
ggatccagtt tacacttttt ctatttcgca aaatccattt cctattgaaa accgggatgt   1380
attgggtgag acacaggact tccatagctt ggccacctat ttgtctcaga atayctcatc   1440
tgtgttcttg gataccatct cagatttcca cctcttgctg ttcctggtca ccaatgaagt   1500
tatgcctctg caggacagca tcagcttgct gctggaggcc gtgcggacca gaaatgagga   1560
gctcgcccag acatggaaga ggtctgagca gtgggccacc atcgagcagc tktgcarttc   1620
acagggtaca tgtgcaggtt tgtcacctgg gattacagac gtgtatacac aagacacaaa   1680
gatcagctca ggatgggtca taggcctaat ggtaaaaggt                         1720

<210> 981
<211> 809
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (788)
<223> n equals a,t,g, or c

<400> 981
ctgcggggcc gcggccagtg cctcagcggt gggaacctgc ggggccgcgg ccggtgcctc     60
ggcggtcggt gttttgtcgc agagtttact ctgcctcccc tctcctgcgc gtgcgtgtgt    120
tcacacaggt tttattttga atttgcatga gtgcagatgt catgcccctt ggcactcaga    180
tcttcgcctg tgatctctga gagggacagt gctctcatgg ccacagcagt cactcgggac    240
tgcgctgcac ccagtgctgg cttctgctct gtggtccacg ttccatttct gccgtggtcc    300
cagcagcgtc gctgtgggtc tggcctgggt tgcgtgtgtt tcgtatgtgg gccgtgctcc    360
ctgcttggtt cccttttcct ggaacgtgtc actgcctccc tgtctcgctc cgtggacatt    420
tctgggaggt caggccgtgg ccacctggcc ccctgttcag gtctgaggct cccacctgct    480
taggttcggg aagctcagga gtgaggccat gccctcctca ggacatccca tccaagccag    540
ccatgtccgg tgatgggccg ctgcccggaa agtccttttc cttcttgtaa ctgagaagaa    600
cttgccttga gccacgtcaa gtcccgtccg tcgcagccac tgcccacaag cgtgagtctg    660
ctgtgagcca gcggctccat ggcagggcat cccagcgcca ttcctgcctt cacacacact    720
tgctgccgtt tccctgtgct gggggctgtg cargtctgcc tcggtgtgga mttttctctt    780
aaggaaanaa ccccaggtcg gccgagcac                                      809

<210> 982
<211> 2373
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1848)
<223> n equals a,t,g, or c

<400> 982
tataccgacg gcatctcctt cgaccctgcc ctcatccatg acaatgcctc atccacccac     60
cccgaagagn cctgctctca tgattggggc ctgctggact gaggagaaga acaaagagaa    120
ggaaaagggg agacaacagt acagacacca cccaaggaga ccctttgtcg atccaccact    180
acttccatgg ctacctggct ggtttcagcg tgcgctcagg tcgcctggag agccgcgagg    240
tcatcgagtg cctctatgca tgtcgggagg ggctggacta tagggatttc gagagcctgg    300
gcaaaggcat gaaggtccac gtgaacccct cacagtccct gctcaccctg gagggggatg    360
atgtggagac cttcaaccat gccctgcagc atgtggctta catgaacact ctgcgctttg    420
ccacgcccgg cgtcaggccc ctgcgcctca ccactgctgt caagtgcttc agcgaagagt    480
cctgcgtctc catccctgaa gtggagggct acgtggtcgt ccttcagcct gacgsccccc    540
agatcctgct gagtggcact gytcattttg cccgcccagc tgtggacttt gagggaacca    600
acggcgtccc tttgttccct gatcttcaaa tcacctgctc catttctcac caggtggagg    660
ccaaaaagga tgagagttgg cagggcacag tgacagacac acgcatgtcg gatgagattg    720
tgcacaacct ggatggctgt gaaatttctc tggtggggga tgacctggat cccgagcggg    780
aaagcctgct cctggacaca acctctctgc agcagcgggg gctggagctc accaacacat    840
ctgcctacct cactattgct ggggtggaga gcatcactgt gtatgaagag atcctgaggc    900
aggctcgtta tcggctgcga cacggagctg ccctctacac caggaagttc cggctttcct    960
gctcggaaat gaatggccgt tactccagca atgaattcat cgtggaggtc aatgtcctgc   1020
acagcatgaa ccgggttgcc caccccagcc acgtgctcag ctcccagcag ttcctgcacc   1080
gtggtcacca gcccccgcct gagatggctg gacacagcyt agccagctcc cacagaaact   1140
ccatgatacc cagcgccgca accctcatca ttgtggtgtg cgtgggcttc ctggtgctca   1200
tggtcgtcct gggcctggtg cgcatccatt cccttcaccg ccgcgtctca ggggccggcg   1260
ggcctccagg ggcctccagt gaccccaagg acccagacct cttctgggat gactcagctc   1320
tcaccatcat tgtgaacccc atggagtcct accagaatcg gcagtcctgt gtgacggggg   1380
ctgttggggg ccagcaggag gatgaggaca gcagtractc ggaggtggcc gattccccca   1440
gcagcgacga gagacgcatc atcgagaccc ccccacaccg ctactaaggc ctacacctct   1500
ccccacgcag agggggaatt ctgccctggt gaaacagaca ctccagacat gggagaagga   1560
ctttctggga acacagagac caagagggag agaggcttca gaaccagtcc tcctttcatt   1620
tcaaaacccc agcgggccct ctggagtccg ccctgcccct cccccggccc cccatccctc   1680
acttctgggc tgtcatgctc ctggtgtgcc ccttgcactg gggctggctg ggttggaaag   1740
tgggctggac ttcagctgcc tttctacccc caatggcagc tgccccctta gcactcactg   1800
tgttggggag agggtgacga ttgcaatggc tggggctggg gctggggntg ggggtgggat   1860
tgaaggaaac cctctcctct ccccttccct tctctctcct gtccatggga agcttttccc   1920
cctctgcagg gctccctcag ctggaccatc gtccctgctt ctcttatgat cgccccacct   1980
catttccatt tcagtctggg gaccccattt ctccctcctt tccaacttcc ttcctttctt   2040
gtcctgtttc ccttcctgcc cttgcagtcc tgaggtcctg cagccccggc ccctcctccg   2100
tgacctggtg tggccaggct gcggggacgg gaggggacgt gggggccccg ggtgtacata   2160
tataatgtat attttttcaa tgttgtcgtg agtgcagccc atgttcctgc gtgcagctca   2220
cggccttgtg tgtatgtgtg tgtgtgtgtg tgtgaggcat cgtcatgtcc tggggcaggg   2280
gcggggggtt gggtgtggtg agggagggga catatcctag ggttttcaaa taaaacaatc   2340
agaaaaaaaa aaaaaaatgc cccccggggg ggg                                2373

<210> 983
<211> 1732
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1568)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1631)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1673)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1701)
<223> n equals a,t,g, or c

<400> 983
cttttatggc gttctttgtt tttgaaacgc tcaccgcgca acgtttacac ccaatgcaat     60
atttgctggt ggggctttca ttggtgatgt tttatttgct cttgctggcg ctttctgaac    120
ataccggttt taccgtggca tggataatcg ccagtctgat tggggcgata atgaacggta    180
tttatttgca agcggtattg aaaggttggt gcaacagcat gttgtttacc ctcgcgctgt    240
tgttgctgga tggtgtgatg tggggactgc tcaactctgc cgatagcgcg ctgttgttgg    300
gaaccagtgt gctggtggtg gcgctggccg gcatgatgtt tgtracccgt aatatcgact    360
ggtatgcgtt ttcactgccg aaaatgaaag ccagtaaaga agttacamcg gacgatgagt    420
tacgtatctg gaaataaggt tgaaaaataa aaacggcgct aaaaagcgcc gttttttttg    480
acggtggtaa agccgattaa tcttccagat caccgcagaa gcgataacct tcaccgtgaa    540
tggtggcgat gatttccggc gtatccggcg tagattcgaa atgtttacga atacggcgga    600
tcgtcacgtc tacagtacgg tcgtgcggtt tcagctcacg gccggtcatt ttcttcagca    660
gttcagcacg ggactgaatt ttgcctgggt tttcacagaa gtgaagcatg gcgcggaact    720
cgctgcgcgg cagcttgtac tgctcgccat cagggccgat caacgaacgg ctgttgatgt    780
ccagttccca accattgaac ttgtagcttt caacgctacg acgttcttcg ctgacagtac    840
ccagattcat ggtacgggac agtaggttgc gtgcacgaat cgtcagttca cgcgggttga    900
acggtttggt gatgtagtca tctgcaccga tttcgaggcc gagaatttta tcgacttcgt    960
tgtcacggcc agtcaggaac atcaacgcaa cattcgcctg ctcgcgcakt kcacgcgcta   1020
acagaagacc gttcttaccc ggcagattga tatccatgat caccaggttg atgtcatatt   1080
cagagaggat ctgatgcatt tccgcgccat ctgtcgcttc gaaaacatca tagccttccg   1140
cttcgaaaat acttttcaac gtgttgcgtg ttaccaactc gtcttcaacg ataagaatgt   1200
gcggggtctg catgtttgct acctaaattg ccaactaaat cgaaacagga agtacaaaag   1260
tccctgacct gcctgatgca tgctgcaaat taacatgatc ggcgtaacat gactaaagta   1320
cgtaattgcg ttcttgatgc actttccatc aacgtcaaca acatcattag cttggtcgtg   1380
ggtactttcc ctcaggaccc gacagtgtca aaaacggctg tcatcctaac cattttaaca   1440
gcaacataac aggctaagag gggccggaca cccaataaaa ctacgcttcg ttgacatata   1500
tcaagttcaa ttgtagcacg ttaacagttt ggatgaatca tcgtattcta atggctagct   1560
tcgtcacnta tttaataatc caactagttg catcatacaa ctaataaacg tggtgaatcc   1620
aatgtcgaga nttaattttt ataaaattaa cccaaggtaa accgaaaggg aanggtaggc   1680
cattttttaa ccaactccaa ncggttaggt taccggttcc ggggaaaata gg           1732

<210> 984
<211> 1608
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1604)
<223> n equals a,t,g, or c

<400> 984
gaattcggca cgaggatttg gaggggacaa acatccaaac catttaagtc acagcacttt     60
actccgcagt gtgaataaca caggcattct cctacataat cacagtacag ttatcatact    120
ctggaaattg aatatcatct aatatacttt ccatacccag attttcttag atttcccaat    180
gatatttctt actgtcctcc ctttagcctt cctctttctc cattcaggat tctaccatta    240
catttcattt tcatgtctct tcagtctctc tttagctttg tttttctttc ttgatgttgc    300
cacttttagg aggccaggcc agttgttttg tgaaagatct gttctctttg atatgtttca    360
ttttggattt gtttcattgt ttttgcatga atggattcag gctaaacatt tttgggcagg    420
actgtttatt gtattaccta gtgatgtgtt cttttcagtc catcatctgg aggcacctga    480
tggcagtttt cccaatattg cgaaattaag tttgattatt ttgttaaggt agtgtccacc    540
agatctctcc attttaaaga catccttttc tctaattact cagtggactg tagagtgatg    600
ctttgaaact gaataactaa cactccctaa ctcagtgatt tagcacccgt tgattttttt    660
tttttgcctg aatcaaatat tattatagta gttttaaatg gkgattttcc atttctattc    720
ttttgttagc tgccattctt ctataatttt gtctttatat tttactgggt gttaagattg    780
ctattccagc tttcctttgt cttttacacc ttttcccatt cttttatttt tttccatccc    840
tttttgtcct gttttccaat agatggatag aattttcttt ctctggttta aaggttatac    900
atttgtgtgt gtgtgtgtat tcttagccat ttgcccttaa aacatagaga tggttattcc    960
tgttgattaa aaaaaactca gtaatgttac tatcttctct ttaataagat aggtacttta   1020
tttcattctg tgttcttggg tgaggtctcc cctcacccag tcaagttgat gttaatctag   1080
aatttttagt tttttaaatt atcgatatac tttctgtctt ttcctttttt tttcactctc   1140
tctgtatttg tgctttcccc ctttactctc tttcccttca ttccttcttt ctcactttct   1200
tcttctattt ttcactcttg ggtagattat cttttagaaa acagcaagat attatataat   1260
ttactttata ttctctttcc aaatgattaa agtaataatt aaaaattttt gatatgtgtg   1320
tatgcaagga taggaatcct cttgtaagtg gaagaactct accacatgca tgagtcatta   1380
gtgtgttaaa cactgggaag tggctttagg tccagctggg tgctctgaag aaggtaggtt   1440
tcttcagttc tttatgttaa ctgtctcctt accttaaaaa aggagtgaag aatactgact   1500
gcagaggttt tgtgaggatt ccggtaacac agaagcatag aactggaaaa gaatattaat   1560
atttgccaaa aaaaaaaaaa aaaaactcga gggggggccc naanccaa                1608

<210> 985
<211> 1118
<212> DNA
<213> Homo sapiens

<400> 985
ggcacgagct acctttctgc ctgctttgct ggctgcaaca gcacgaatct cacgggctgt     60
gcgtgcctca ccaccgtccc tgctgagaac gcaaccgtgg ttcctggaaa atgccccagt    120
cctgggtgcc aagaggcctt cctcactttc ctctgtgtga tgtgtatctg cagcctgatc    180
ggtgccatgg caagacaccc tcagtcatca tcctcatcag gacagtcagc cctgaactca    240
agtcttacgc tttgggagtt ctttttctcc tccttcgttt gttgggcttc atccctccac    300
ccctcatctt cggggctggc atcgactcca cctgcctgtt ctggagcacg ttctgtgggg    360
agcaaggcgc ctgcgtcctc tacgacaatg tggtctaccg atacctgtat gtcagcatcg    420
ccatcgcgct caaatccttc gccttcatcc tgtacaccac cacgtggcag tgcctgagga    480
aaaactataa acgctacatc aaaaaccacg agggcgggct gagcaccagt gagttctttg    540
cctctactct gaccctagac aacctgggga gggaccctgt gcccgcaaac cagacacata    600
ggacaaagtt tatctataac ctggaagacc atgagtggtg tgaaaacatg gagtccgttt    660
tatagtgact aaaggagggc tgaactctgt attagtaatc caagggtcat ttttttctta    720
aaaaaagaaa aaaaggttcc aaaaaaaacc aaaactcagt acacacacac aggcacagat    780
gcacacacac gcagacagac acaccgactt tgtccttttt ctcagcatca gagccagaca    840
ggattcagaa taaggagaga atgacatcgt gcggcagggt cctggaggcc actygcgcgg    900
ctgggccaca gagtctactt tgaaggcacc tcatggtttt caggatgctg acagctgcaa    960
gcaacaggca ctgccaaatt cagggaacag tggtggccag cttggaggat ggacatttct   1020
ggatacacat acacatacaa aacagaaaac attttttaaa agaagtttcc taaaataaaa   1080
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                           1118

<210> 986
<211> 1813
<212> DNA
<213> Homo sapiens

<400> 986
agtaggatcc agtctgtggg gctcatttga gggagaatga gcacggggct tttggaggct     60
gcagcctagg gccaagggat ggaggctcac ctgagtgcag gttaggcagt gaagtgtctc    120
cccggaaacc aagctagagt gccccacctg ctcggccctg ccttctcgga tcggatccag    180
cacatccagg cttctcctcc tcccgaggaa ccagtggtga cagctgaggc catgtgagta    240
ggatcctgaa tgaggcttta tctctggctg ttcgtcccat cgtccaccgt ggcaccagct    300
ccctcagcca gccgggatgg gaccagcgac tgagagagcc agaggcagag aggtgagggt    360
gaccatatcc tggactgtga gaggaatggg actctgggcc tgtagctgcc aagcaggtgg    420
caggtgctcc aggctgtgat ctgcaccctc tgacccctga cattgacctc ctaccctgac    480
ccctgcctga ccaagccatg tctgaacagg aggctcaagc cccagggggc cgggggctgc    540
ccccggacat gctggcagag caggtggagc tgtggtggtc ccagcagccg cggcgctcgg    600
cgctctgctt cgtcgtggcc gtgggcctcg tggcaggctg tggcgcgggc ggcgtggcac    660
tgctgtcaac caccagcagc cgctcargtg aatggcggct agcaacgggc actgtgctct    720
gtttgctggc tctsctggtt ctggtgaaac agctgatgag ctcggctgtg caggacatga    780
actgcatccg ccaggcccac catgtggccc tgctgcgcag tggtggaggg gccgacgccc    840
tcgtggtgct gctcagtggc ctcgtgctgc tggtcaccgg cctgaccctg gccgggctgg    900
ccgccgcccc tgcccctgct cggccgctgg ccgccatgct gtctgtgggc attgctctgg    960
ctgccttggg ctcgcttttg ctgctgggcc tgctgctgta tcaagtgggt gtgagcggac   1020
actgcccctc catctgtatg gccactccct ccacccacag tggccatggc ggccatggca   1080
gcatcttcag catctcagga cagttgtctg ctggccggcg tcacgagacc acatccagca   1140
ttgccagcct catctgacgg agccagagcc gtccttcttc tcacagcggc ctcagcgtcc   1200
ccagagccga gccagggtgt gagtgcatgt gaacgttgag tacacatgag tgcgtgtatg   1260
cccccaggct gggtcagctc ttctgtggat tgcatggcgt gtgattaaaa gcccatgtgt   1320
tcccacacat ccacatcatg ggaaggttaa tgtgtgcctc cttggaactg ggtgttggtg   1380
tccatggaac ttcctctctg tatctcaggt cagtaggcgc agaaacgcct catgatgaag   1440
attcttgagc cccatttcca agacccctca catccaatcc tgtcctgtaa catccatcaa   1500
ggatttccat aggggtgact ggtgcccacc caagactgca ccagtgcctg ctcattgagg   1560
agagtaactg ctggccaggc agaaagaata tgggctctgc aatgagacag acctggaggg   1620
gactctcccg ttgagcacta gcagctggag gagttgggag ttcatggcta tcatggttgt   1680
gttaatcgat tgtggggatg aaatgtcatt gtgtatggaa ggcggggctc atggctgatt   1740
ggcaataaaa tggcggctgc cgttgtcatt gtctccaaaa aaaaaaaaaa aaaaaaaaaa   1800
aaagtcgtat cga                                                      1813

<210> 987
<211> 637
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (529)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (605)
<223> n equals a,t,g, or c

<400> 987
gataatccca atcgtcccct ggcagaatgc cagttttgcc ataagaagtt tacaaggaat     60
gactacctca aagtgcacat ggacaatatc catggtgtag ctgacagcta ataggggctg    120
taaaggaatt aaactattca gaagggctcc taatatgaat cccagatttt tatcacctga    180
tcagcataac agaagtagcc aaaagtgact tactggtctc atagttctta tttgcctaca    240
tttagagtct gtagatgcat atgcaaccaa aaaaaagtct tacttttaac aagaaatggt    300
ataaatggaa aaaaatacaa ctccatagcc ttgcaaaatg caacttgtgc tctgtcttat    360
aaaaatggag aaaggagtca tggctctctt tcttggccat ccctctgtaa tgaagtttat    420
aatatactty cctaataggc ctttttattt tattgktatt ctttgkgtgt ctgtgtgtct    480
gtgtgtctgt atgtgtctgt gtgtgtgcac tcacttgcaa atgccagtng ttgcagctgg    540
ttttaccaat ttaaatagaa ataaatcaag atatccaact atttctttgc agatgagggt    600
aagantaagt ttatcaaagt ctcaagtttt gataggg                             637

<210> 988
<211> 1205
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1202)
<223> n equals a,t,g, or c

<400> 988
aggaagcaat cctcttacct ccgcttccca agcagctggg gccacagatg gagttttgct     60
ctagcctggg ggagaaagtg aactccctct caaaaaaaag accactctca gtatctctga    120
tttctgaaga tgtacaaaaa aatatagctt catatatctg gaatgagcac tgagccataa    180
aaggttttca gcaagttgta acttattttg gcctaaaaat gaggtttttt tggtaaagaa    240
aaaatatttg ttcttatgta ttgaagaagt gtacttttat ataatgattt tttaaatgcc    300
caaaggacta gtttgaaagc ttcttttaaa aagaattcct ctaatatgac tttatgtgag    360
aagggataat acatgatcaa ataaactcag ttttttatgg ttactgtaaa aagactgtgt    420
aaggcagctc agcaccatgc ttctcgtaaa agcagcttca attatccact ggggttatct    480
tttgacaact tgccattatc tgatgttaca caattcaata gcaagcaagt ttgagacaat    540
cgcagtttaa aagcatgaac catttaacaa aaagtggaat aattaaagat aaagcacttc    600
ttcccaaagg gaattatcac ctagtgaaaa attatgcatt tcatctactc agttaccgac    660
tgcaagtctc tcctcgctct agctctcaag ctttgggtga atattcctgt gaaatatatc    720
ttcaacttga aagttcatac tccaatcaaa aactcctttt actgagtttg cagtactgta    780
tttgcactgt ttgtattcct ctgggccctt attgctactt ttgctttcct ttgttacaca    840
gattttgtgt tgcacttttt ctccagaggg gtgttgtaga gccttggttg tatgaataat    900
accagtggta gtgtccacgg gtctaatgta agcccatttg gcatcactcc tctcctctct    960
cttgagagga tttcttgtgc acagagtatg aagcagttgt ggagcgctgt gcctttgtca   1020
agataccatc ttgtttgatg atttctttct ttgctgtttt ttcttcaaaa tgttagtaag   1080
ctctgtcatg cttctagcaa attgtaagac taattatttg tttccacctc ataacctgtt   1140
gcaataaata ttacttctca tacaaaaaaa aaaaaaaagg ggggcccttt taaagggacc   1200
antta                                                               1205

<210> 989
<211> 1855
<212> DNA
<213> Homo sapiens

<400> 989
ggagactgcc tggttctctc tgatgttcaa ggtggtgggg ttctgagaca cttgggggaa     60
ttgtggggat attctagcca ccagttctct tcttcctttg ctaaattcag gctgcaggct    120
ccttccatcc agataactcc atcctgtcga gtaggctctt tctgaccctc agaaatacat    180
tgtccttttt cctctttgcc catttttctt ccctctcttc ctccccatga gaagtctgct    240
tgtagtatta gaatgttatt gttgactctc tcccaagtgc cttgatcttt gtaatatctc    300
ctgttgtttc tatgatatag gagctagggg aagggggttg tttgccttct tcaggacctg    360
actggacaga tggacctggc tcaagcaact actctggatg cactttgctg tgtgggatga    420
actaaaagtg tctgaatttt gctgataact ttataaaact cactatggca tgcttccctc    480
ctggtgggcc ctaggatgga tgacactcaa gatactacag atgtgggtgc aggcatgcac    540
acacacgatg gaatatggcc attcctacac aggtggggta gagagtgggt cagcagcctg    600
gcacctcaca gaggtgggac ctaagaggac tcatgattat gcagagaatt ggattgggtc    660
tctgtcatag attgagtaat ctcttccctt acctcaattc catctccacc catctctaca    720
tctgggcaca gcaacccaga gatggccaaa agcattcaag cctgggggaa gatgtttgac    780
tattgctgct cttcaccaga acctcacacc tctcctggga ctggaaccct tcagtgggtg    840
tgtggccagt tttggaggct ggaatgatgg gccagggtgt aggattcatt ctccatgtaa    900
agtttccttt catcctgcct agccatcccc aaggtttatt tccagaagaa aggaatatct    960
ctacttggat caattctggt catttcaaga ggatggaggc ctcaagtgtg ggaacttccc   1020
ctactccctg gatgtgtgta cctagcacac ttccttctcc cacccctttt tccagttgga   1080
tttgtttttc tgttctcttc tgtcctgtct tatactgcaa ctgtgtctcc taggggacag   1140
atggccttct ttgtcatctt cactctccac ccccagagag gagtcagagc cataactcaa   1200
tcactcagcc cctccaaaga tagttgatgt gtgataatct cataatgttg agaaccctga   1260
tgagatacat tgtcttcctc tccctacaat gcctctgggg ccaaggcacc cattcttctt   1320
gctatcctcc atcccccttg aggcttccac tttttttttt tttagacata aagctgggca   1380
tcagcaactg gcctgtggtg atgcaaagct gctttgctct gtatctggct ggactgatct   1440
gtctcacaag aagccatgag gccataggga gaagctccct ctccccttca tcttctgctc   1500
caaaggtggt agcaagagga gtacccagtt aggggttgga gcccccatat aacatcttcc   1560
tgtcagaaga ctgatggatc tttttcattc caaccatctc cctttccccc gatgaatgca   1620
ataaaactct gtgacaccag caaccattgc tctttagaaa tgggttttct gatcatatgg   1680
ctgatgtgtt atgggcagta tggatgtctt catttgttgc ttctgttttt catctttttt   1740
gttttattaa taaaaattta tgtatttgct cctgttacta taataataca gggaataaat   1800
tattcaatcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaac tcgag        1855

<210> 990
<211> 1035
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1033)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1034)
<223> n equals a,t,g, or c

<400> 990
cggagatcca gtgaaagagt gttcatctca gaatgttact atgtcatgta gtgaaggctt     60
caaaaaccta ttttaccgaa cttacatgct ttttaagaat gcttctggta agagacgatt    120
tttgctctgt ttgttacttt ttacagtaat cacttatttt tttgtggtaa ttggcattsc    180
cccaattttt atcctttatg aattggattc accactctgc tggaatgaag tttttatagg    240
ttatggatca gctttgggta gtgcctcttt tttgactagt ttcctaggaa tatggctttt    300
ttcttattgt atggaagata ttcatatggc cttcattggg atttttacca cgatgacagg    360
aatggctatg accgcgtttg ccagtacaac actgatgatg tttttagcca gggtgccgtt    420
ccttttcact attgtgccat tctctgttct acggtccatg ttgtcaaaag tggttcgttc    480
gactgaacaa ggtaccctgt ttgcttgtat tgctttctta gaaacacttg gaggagtcac    540
tgcagtttct acttttaatg gaatttactc agccactgtt gcttggtacc ctggcttcac    600
tttcctgctg tctgctggtc tgttactact tccagccatc agtstatgtg ttgtcaagtg    660
taccagctgg aatgagggaa gctatgaact tcttatacaa gaagaatcca gtgaagatgc    720
ttcagacagg tgactgtgat ttaaacaaac aaaaaaaatc tatgaatgca catatcatat    780
accatgactt ctgaagacta taaatgaatt ccacaatcag tgcttcactg agaaccaatt    840
ttacctatct tttcttctaa actgaacagt cagagagaca gctcctggct ttagcttctt    900
gtggtaccac gcactttgag cactttgtgc gtatcatgca atatacttgc aataccacag    960
aaccaatttt caaatacgcc tcacttttta gacttagaag aggaaccttt aaacttaagg   1020
ggggtaggaa ggnnc                                                    1035

<210> 991
<211> 2104
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<400> 991
cgtgcgnnta tatgacttct tcctggcctg ccacccactg atgccgattt actttgcagc     60
cgtgattgtg ttgtatcgcg agcaggaagt cctggactgt gactgtgaca tggcctcggt    120
ccaccacctg ttgtcccaga tccctcagga cttgccctat gagacactga tcagcagagc    180
aggagacctt tttgttcagt ttcccccatc cgaacttgct cgggaggccg ctgcccaaca    240
gcaagctgag aggacggcag cctctacttt caaagacttt gagctggcat cagcccagca    300
gaggcctgat atggtgctgc ggcagcggtt tcggggactt ctgcggcctg aagatcgaac    360
aaaagatgtc ctgaccaagc caaggaccaa ccgctttgtg aaattggcag tgatggggct    420
gacagtggca cttggagcgg ctgcactggc tgtggtgaaa agtgccctgg aatgggcccc    480
taagtttcag ctgcagctgt ttccctgaaa gccagagaag accttcctct tacatcacat    540
taaggtctca cccttccatg gaaggattgg gaggggtgga atttccttta ttaaaagggt    600
ttctgtccag agttttttat tcctgccacc ctgccctgcc cgtttgtgtt tgcctttact    660
tcagaggcca rtagcagagc ctacctgaca cagaggggac ctgggggcct ggcacagaat    720
cttatgcctc tcccagtggg cttttggatg ggctctctgc cacctccctg gtgttggagg    780
aagtgggttt ctgaagcttg cagctgcttt tgcaacctgc tgggcctggg ctgccctagt    840
taccgggaac ctcctagtca ccccatagaa ggtgaactgg aacatgggat gccctcttac    900
tgctcctgct tgcctgcatc agatggacac agaaggaggg ggctgctgct gaaggagtca    960
ggcttgggat ggagagcaag aggccaaagg actcgtctgg gagcatgatc ggcccctctt   1020
actagcagct ccatcagctg atcagaaatc agagacagaa gggaactagg ttactcgtta   1080
aatcctacct attttcagcc tagaaatcac atgggcgttt ccagtcaagt gggaaggaag   1140
ctcattttta gggcctagac ctagactagt tttgcctgcc tttttttcct ccctgctttc   1200
ttctacaagc cacacaacat tgcttataaa aggtactttt attactattt ttagaatata   1260
tacaccccat atgtaaatta ccctcacttt taaagtaata atagttcctt cacggaaaaa   1320
aaaatagttc tcatcagaag gatgagcttc taagatcctg aattttactt tctacttgat   1380
taacattttc gctttagcca gagttgctat ttgcaaacag ctttccactt ccaaagtgcc   1440
actttctgac cggtttttct tcctgttttc ctcaaatcat cctactccca aataggcacc   1500
cactcactac cttggcgtcg ttttttgggt ctgacttgtc tcgtcaactg ctggtctctc   1560
ccacctggtt ggaaatgtcg ttggaaactt gcaaagactc tccagacctt agggaacaag   1620
aggcatcact cagtccttct gggacagctt ccctgtaagc aaagccaggt ttgttttaga   1680
ttcactctgg cctgaaaaaa aaagtgcctt ttgctgcttt aaaraattgg ggtatatggt   1740
atgaagcagc catgtacttg tattttcctg gtctttcctg ggcactcttc tctcttggca   1800
gatgttttct taaagtgaac acaccagaag cactctaccc caccatatcc agtcctcttt   1860
gcatgcctgt tgtgtgcagg gtggagggtg tcccacgtgc cagagcagct gggagccctg   1920
tccgctgagt tacactaagc actktatttt attyatttat attatttttt tttttctggg   1980
cattagagca gactccatct cataataata atacataata agctattatt ttctacctga   2040
tgtcatcagg tgttaatcca cctctatatc tgttggccag tgaaatactt tgggctggga   2100
cgtt                                                                2104

<210> 992
<211> 646
<212> DNA
<213> Homo sapiens

<400> 992
gtcgactttt tttttttttt ttttgatatt tattatgttt attcataatt tgattgcttg     60
tttgtgcagt gcttagtgga cagcacatct cagggagcct cccagagcct ggggtggaat    120
acggtcatgg accatacagg aagcttcacc agactgggag gctgagggcc ttccccgagc    180
ctttctgctg atagggaagg cagagaaact gagagcatca ccatttcttc agttagtgct    240
ttctcctttc tgtaattcct gttagtcatc atcatcatca tcctctggaa caaaaatgtc    300
atgttcctca agtagagcag caaagttctt gctaatgagt gtcccgacat agagaaaggg    360
gatcacaatg gagaacacac ggagaaggcc gaaggacatt ttcaccggtt tgggcaaaat    420
ggcgccgctg cgggtaacga tgactgacct cgacggtacc aggctccggc ctgagccgct    480
ccatgcggcg gagacatcgc catctttcct caagctaggc ccgctccgga gagccccgga    540
cctgacgggt gccaatacta gccagcgagc cgctccggac gccatgcccc cagctccgcc    600
cctcacccgg gcacccgcac cccaccgccc agccctcgtg ccgccc                   646

<210> 993
<211> 593
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (579)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (580)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (586)
<223> n equals a,t,g, or c

<400> 993
caatggcaat ccaccatcgt gcaggccaac ctgcacaaca gagtgatttg attaacgtcg     60
cccaactgac ggcgcaatat tatgtactga aaccagaagc agggaatgcg gagcacgcgg    120
tgaaattcgg tacttccggt caccgtggca gtgcagcgcg ccacagcttt aacgagccgc    180
acattctggc gatcgctcag gcaattgctg aagaacgtgc gaaaaacggc atcactggcc    240
cttgctatgt gggtaaagat actcacgccc tgtccgaacc tgcattcatt tccgttctgg    300
aagtgctggc agcgaacggc gttgatgtca ttgtgcagga aaacaatggc ttcaccccga    360
cgcctgccgt ttccaatgcc atcctggttc acaataaaaa aggtggcccg ctggcagacg    420
gtatcgtgat tacaccgtcc cataacccgc cggaagatgg tggaatcaaa tacaatccgc    480
caaatggtgg cccggctgat accaacgtca cttaaaagtn ggtgggaaag aacaggggcc    540
aaacgcactg gttgggccca atgggcctgg aaaagggcnn tgaaanccgt aat           593

<210> 994
<211> 2176
<212> DNA
<213> Homo sapiens

<400> 994
aattcggcac gagccggctt ttcgagtcag tgctgccgcc gctgcccgcg gctttgcaga     60
gcaggatgaa tgtgatagac cacgtgcggg acatggcggc cgcggggctg cactccaacg    120
tgcggctcct cagcagcttg ttacttacaa tgagtaataa caaccctgag ttattctccc    180
cacctcagaa gtaccagctt ttggtgtatc atgcagattc tctctttcat gataaggaat    240
atcggaatgc tgtgagtaag tataccatgg ctttacagca gaagaaagcg ctaagtaaaa    300
cttcaaaagt gagaccttca actggaaatt ctgcatctac tccacaaagt cagtgtcttc    360
catctgaaat tgaagtgaaa tacaaaatgg ctgaatgtta tacaatgcta aaacaagata    420
aagatgccat tgctatactt gatgggatcc cttcaagaca aagaactccc aaaataaaca    480
tgatgctggc aaacctgtac aagaaggctg gtcaggagcg cccttcagtc accagctata    540
aggaggtgct gaggcagtgc ccattagccc ttgatgccat tctaggcttg ttgtcccttt    600
ctgtaaaagg ggcagaggtg gcatccatga caatgaatgt gatccaaacc gtgcctaact    660
tggactggct ctctgtgtgg atcaaagcgt atgcttttgt gcacactggt gacaactcaa    720
gagcaatcag taccatctgt tcactagaga aaaaatcctt attgcgagat aacgtggacc    780
tattgggaag cttggcagat ctgtacttca gagctggaga caataaaaac tctgtcctca    840
agtttgaaca ggcacagatg ttggatcctt atctgataaa aggaatggat gtatatggct    900
acctactggc acgagaaggg cggctagagg atgttgagaa ccttggatgc cgccttttca    960
atatctctga tcagcatgca gaaccgtggg tggtttctgg ctgtcacagc ttctatagca   1020
aacgctactc ccgggccctc tatttaggag ccaaggccat tcagctgaac agtaatagtg   1080
ttcaagctct gctacttaag ggagcagcac ttaggaacat gggcagagtc caagaagcaa   1140
taatccactt tcgggaggcc atacggctcg caccttgtcg cttagattgt tatgaaggtc   1200
ttatcgaatg ttacttagcc tccaacagta ttcgagaagc aatggtaatg gctaacaacg   1260
tttacaaaac tctgggagca aatgcacaga cccttaccct tttagccacc gtttgtcttg   1320
aagacccagt gacacaggag aaagccaaaa cattattaga taaagccctg acccaaaggc   1380
cagattacat taaggctgtg gtgaaaaaag cagaactact tagcagagaa cagaaatatg   1440
aagatggaat tgctttgctg aggaacgcac tggctaatca gagtgactgt gtcctgcatc   1500
ggatcctagg agatttcctt gtagctgtca atgagtatca ggaggcaatg gaccagtata   1560
gtatagcact aaggtaggca ctagcctccc ttgggggaag gccactgagg agggtagagg   1620
aggcagtgag ctgtgtcaca ggagttatgg aaacacacac acactttgtg tccatggttg   1680
aaagcagaat aataatagta atggtagaag agttatttgt gaattcatga cttctaaaaa   1740
ttttttctta aaatatatta acaacattag agaactgttt cactcataac catcccacac   1800
cactataaca tctgtgttca tttgtatagc tcatcttctg tccttgccca cacacacata   1860
tttttatagg gctgtaccta gtatatattt tatattcttc tttttcaaat caaagtattg   1920
taagtacttt cccatgtttc tatctactgt agtcattaag aacttgaggt ctgaagtttt   1980
gaatactacc ttcaccacct gtgatcttgg gcaagttact aacacatttc cttgtctata   2040
tctagctacc ttattagata ttaaatgatc gaatgagggt taaatgatta tttcatgtaa   2100
agctcttagc cctgtgcctg gtacatagta aatgctaaat aaatagtggt attcttactg   2160
tttaaaaaaa aaaaaa                                                   2176

<210> 995
<211> 1539
<212> DNA
<213> Homo sapiens

<400> 995
cgcagcttga tggcgtcggg ctggagagcc gcagtcccgg ctgcagcacc tgggagaagg     60
cagaccgtgt gagggggcct gtggccccag cgtgctgtgg cctcsgggag tgggaagtgg    120
aggcaggagc cttccttaca cttcgccatg agtttcctsa tcgactccag catcatgatt    180
acctcccaga tactattttt tggatttggg tggcttttct tcatgcgcca attgtttaaa    240
gactatgaga tacgtcagta tgttgtacag gtgatcttct ccgtgacgtt tgcattttct    300
tgcaccatgt ttgagctcat catctttgaa atcttaggag tattgaatag cagctcccgt    360
tattttcact ggaaaatgaa cctgtgtgta attctgctga tcctggtttt catggtgcct    420
ttttacattg gctattttat tgtgagcaat atccgactac tgcataaaca acgactgctt    480
ttttcctgtc tcttatggct gacctttatg tatttcttct ggaaactagg agatcccttt    540
cccattctca gcccaaaaca tgggatctta tccatagaac agctcatcag ccgggktggt    600
gtgattggag tgactctcat ggctcttctt tctggatttg gtgctgtcaa ctgcccatac    660
acttacatgt cttacttcct caggaatgtg actgacacgg atattctagc cctggaacgg    720
cgactgctgc aaaccatgga tatgatcata agcaaaaaga aaaggatggc aatggcacgg    780
agaacaatgt tccagaaggg ggaagtgcat aacaaaccat caggtttctg gggaatgata    840
aaaagtgtta ccacttcagc atcaggaagt gaaaatctta ctcttattca acaggaagtg    900
gatgctttgg aagaattaag caggcagctt tttctggaaa cagctgatct atatgctacc    960
aaggagagaa tagaatactc caaaaccttc aaggggaaat attttaattt tcttggttac   1020
tttttctcta tttactgtgt ttggaaaatt ttcatggcta ccatcaatat tgtttttgat   1080
cgagttggga aaacggatcc tgtcacaaga ggcattgaga tcactgtgaa ttatctggga   1140
atccaatttg atgtgaagtt ttggtcccaa cacatttcct tcattcttgt tggaataatc   1200
atcgtcacat ccatcagagg attgctgatc actcttacca aggtgatact atgaccatga   1260
gtagcatcag ccagaacatg agagggagaa ctaactcaag acaatactca gcagagagca   1320
tcccgtgtgg atatgargct ggtgtagagg cggagaggag ccaagaaact aaaggtgaaa   1380
aatacactgg aactctgggg caagagatgt ctatggtagc tgagccaaac acgtaggatt   1440
tccgttttaa ggttcacatg gaaaaggtta tagctttgcc ttgagattga ctcattaaaa   1500
tcagagactg taaaaaaaaa aaaaaaaaaa agggcggcc                          1539

<210> 996
<211> 1833
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<400> 996
ggcacgagcc acataaaaga tgtgttacat cagaattttn agagttataa gcctgaagta     60
caggagctga tttgtgtggc tgatcgtttg ggatccctga tgcaatatga aacacctggt    120
ttcctgccaa acaagagaat acacagagct atgggtttgg ccgcattgga ggtcatgcaa    180
gccgtgcagc gtacatggac caactcgaaa gttcgaatga atgggaagac acggttgatg    240
cagtggagag acatgtttga cattgcagtt aaatggagaa ggattgctga cccagaccag    300
cccgtgctgt ggttagatca aatgccagca cgaagtctta gcagaggttt taacaaccac    360
attaatttaa tcaggggtca ggtgatcaac atgagatacc tagaatattt tgagaaaata    420
cttcatttta ttaaagacag aattcttgtt tatcatggag ctaataatcc taaaggattg    480
ctggaagttc gggaagccct ggaaaaggta cacaaagtag aagaccttct tccgattatg    540
aagcagttta atactaaaac gaaggatggg ttcaccgtga acacaaaagt tcccagcctt    600
aaagaccaag ggaaggaata tgatggattc acaatcacga ttacaggaga caaagttggc    660
aatatattat tttctgtgga aactcaaacc acggaagaaa ggacacaatt atatcatgct    720
gaaatagatg cactttataa agatttgaca gcaaaaggaa aagtattgat tctttcatca    780
gaatttgggg aggctgatgc tgtctgcaac ttaatcttat ccttagttta ttacttttat    840
aatttaatgc cactctctcg aggatccagt gtaattgctt actcggtcat cgtgggagca    900
ctgatggcaa gtggaaaaga agtagcagga aaaattccca aagggaagtt agtcgacttt    960
gaagctatga cagcccctgg ttcagaggcc tttagcaaag tcgccaaaag ctggatgaac   1020
ttgaaaagta tttcaccttc ttataagact cttccatcag twtcagaaac gtttccaacg   1080
ttaagatcga tgattgaggt gctaaacaca gactcttctc cacgttgtct taagaaactc   1140
tagttctgct gctgtattta tacaagtaaa gggccggacc tcttgcttct taagttattt   1200
tttaaaacat ggaattataa agaaattagg tcctctatta cttttggata ccaattttta   1260
taggaattga atacttgaaa tcattttctt tacttttctg aaccataatg aaaatcatga   1320
aagaggcttt cggggggaaa aagctacttg acttggaggg aaagcgtatg tattagccgg   1380
cagcctgttg gttcccactt ataaagtcat ataactcctt ccttacagta aaaaaaattt   1440
tcctcaacaa ctaaaatata atactgaaga tgaacaaaaa caaaaccaaa taggagtgtt   1500
tgtattcctt tagagatctg gatatttttc aaagacttgc tttttacgca cattgtgata   1560
gagcatcttt tgttgactca cgtaacctcc atgtgtgggt cctttgtttt attagaacca   1620
tggaagaagg ttcctgggcc atcagtatgt gttgcagagc tcacagccag gaacacttat   1680
tttgaacaat gcagacagta cttgccagag tcccaaatgc tgaattattg aaccatgttt   1740
ttttttcctt tgttgaaaaa aataaaccag ggtgatttct ataaatcacc agtttttggc   1800
attgaaaaaa aaaaaaaaaa aaaaaaaaaa aaa                                1833

<210> 997
<211> 2881
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1667)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2865)
<223> n equals a,t,g, or c

<400> 997
agggtaacat tcaacaatct atccatctcc ggagaacttg aagctgttca gaatatggta     60
tctactgttg aatgtgctct taaacatgtc tcagattggt tggatgaaac aaataaaggc    120
acaaaaacag agggtgagac agaagtgaag aaagatgagg ccggagaaaa ctattccaag    180
gatcaaggtg gtcggacatt gtgtggtgta atgaggattg gcctggttgc aaaaggcttg    240
ctgattaaag atgatatgga cttggagctg gttttaatgt gcaaagacaa acccacagag    300
accctgttaa atacagtcaa agataatctt cctattcrga ttcagaaact cacagaagag    360
aaatatcaag tggaacaatg tgtaaatgag gcatctatta taattcggaa tacaaaagag    420
cccacgctaa ctttgaaggt gatacttacc tcacctctaa ttagggacga attggagaag    480
aaggatggag aaaatgtttc gatgaaagat cctccggact tattggacag gcagaaatgc    540
ctgaacgcct tggcgtctct tcgacatgcc aaatggtttc aggcaagggc aaatggatta    600
aaatcatgtg taattgtcct ccgcattctg cgtgatttgt gcaacagagt ccccacatgg    660
gcaccattga aaggatggcc actagaactt atatgtgaaa agtctatagg tacttgtaat    720
agacctttgg gcgctgggga ggccttgaga cgagtaatgg agtgtttggc atctggaata    780
ctacttcctg ggggtcctgg tcttcatgat ccttgtgagc gagacccaac agatgctctg    840
agctatatga ccatccagca aaaagaagat attacccaca gtgcacagca tgcactcaga    900
ctatcagcct ttggtcagat ttacaaagtg ctggagatgg acccccttcc atctagtaag    960
ccttttcaga agtattcctg gtcagttact gataaagaag gtgctgggtc ttcagctcta   1020
aagaggccat ttgaagatgg attaggggat gataaagacc ccaacaagaa gatgaaacga   1080
aacttaagga aaattctgga tagtaaagca atagacctta tgaatgcact aatgaggcta   1140
aatcagatca ggcctgggct tcagtataag ctcctatctc agtctggccc cgttcatgcc   1200
ccagtcttca caatgtctgt agatgtggat ggcacaacat atgaagcctc aggaccatcc   1260
aagaaaacag caaaacttca cgtagcggtg aaggtattgc aggcaatggg atatccaaca   1320
ggctttgatg cagatattga atgtatgagt tccgatgaaa aatcagataa tgaaagtaaa   1380
aatgaaacag tgtcttcaaa ctcaagcaat aatactggaa attctacaac tgaaacctcc   1440
agtaccttag aggtaagaac tcagggccct atcctcacag caagtggcaa aaaccctgta   1500
atggagctca atgaaaaaag aagaggtctc aagtatgaac tcatctcaga gactggtgga   1560
agccatgaca agcgctttgt aatggaggta gaagtagatg gacagaaatt cagaggcgca   1620
ggtccaaata agaaagtggc aaaggcgagt gcagctttag ctgcctntgg gagaaactgt   1680
tttctggacc caatgcggca aataataaga aaaagaagat tatccctcag gcaaagggcg   1740
ttgtgaatac agctgtgtct gcagcagtcc aagctgttcg gggcagagga agaggaactc   1800
taacaagggg agcttttgtt ggggcgacag ctgctcctgg ctacatagct ccaggctatg   1860
gaacaccata tggttacagc acagctgccc ctgcctatgg tttacccaag agaatggttc   1920
tgttacccgt tatgaaattt ccaacatatc ctgttcccca ctactcattc ttttagcaaa   1980
tgacagaagc taattcctat tgaacaacaa tacagtacaa cacagaatgt tagagaaaaa   2040
gcctttttat cctgctttct ttgaacacat acttgatcaa aattatttgt aaagaacatc   2100
tttcctactt tttgatttta acaaatgcaa atttagttct ctaaaacttg aaaaaaaaaa   2160
aagaaaccag ttctgtgaaa acggtacctc atttctggaa aataacttat accagccctt   2220
ctgttctagg gaaataaaag tctagcagtt caaagtttaa gttttaagag acgtatcaga   2280
ttatgtaaaa ttaaatttgt gaaggatgta tagagtctca aacactgatc acaaataaac   2340
tgctttgttg taacacagag tactgcctgg ttcctgatgc agtcactgat tcttagttga   2400
ttgatatgta tttgccccag ggcactttaa tttgggctgt agttattttt tttaatacaa   2460
tagagacttt tcatttaact ttaactttgt aaatattgaa gtgtgtaata aagccaataa   2520
aatatgggtt tgaatattgt tttagcttat tatttttgat atgttttggt atcaaattac   2580
aaggaattga aaactaataa cttagcccta gaagcccatt cacttgtaag caaagtgcta   2640
aaacaaagca aaggtgattg ttagtttgag ccagtctact cactttgtaa gccctttgta   2700
ctcctgttgt acaagggcca tccccatgat aaaggttcca ttctgttatt tgagcattgc   2760
ttattaaaat gatggcacta cccagagatg gggaaggaga atgtgattat cctagtttat   2820
gaatttccaa gtttttaaaa ataataaatt aatcaatcaa tcmcnaaaaa aaaaaaaaaa   2880
a                                                                   2881

<210> 998
<211> 2060
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1804)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1991)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2024)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2053)
<223> n equals a,t,g, or c

<400> 998
gcccaccacg gcctctctcg gcgaggaaac tctggcctcc gcttcctcct cctccgactc     60
ggacaccggc ggagcctccc cgcccccgcg gaagaaaccc cgccagcaac aatagcaaca    120
gcctgaatgt caataacggg gttcccggcg gggcggccgc cgcatcctca gccaccgtcg    180
cagctgcctc cgccaccacc gccgcctcct cttccttggc caccccagaa ctgggcagca    240
gcctcaagaa gaagaagcgg ctctcccagt cagatgagga tgtcattagg ctaataggac    300
agcacttgaa tggcttaggg ctcaaccaga ctgttgatct cctcatgcaa gagtcaggat    360
gtcgtttaga acatccttct gctaccaaat tccgaaatca tgtcatggaa ggagactggg    420
ataaggcaga aaatgacctg aatgaactaa agcctttagt gcattctcct catgctattg    480
tggtaagagg cgcacttgaa atctctcaaa cgttgttggg aataattgtg aggatgaagt    540
ttttgctgct gcagcagaag tacctagaat acctggagga tggcaaggtc ctggaggcac    600
ttcaagttct acgctgtgaa ttgacgccgc tgaaatacaa tacagagcgc attcatgttc    660
ttagtgggta tctgatgtgt agccatgcag aagacctacg tgcaaaagca gaatgggaag    720
gcaaagggac agcttcccga tctaaactat tggataaact tcagacctat ttaccaccat    780
cagtgatgct tcccccacgg cgtttacaga ctctcctgcg gcaggcggtg gaactacaaa    840
gggatcggtg cctatatcac aataccaaac ttgataataa tctagattct gtgtctctgc    900
ttatagacca tgtttgtagt aggaggcagt tcccatgtta tacgcagcag atacttacgg    960
agcattgtaa tgaagtgtgg ttctgtaaat tctctaatga tggcactaaa ctagcaacag   1020
gatcaaaaga tacaacagtt atcatatggc aagttgatcc ggatacacac ctgctaaaac   1080
tgcttaaaac attagaagga catgcttatg gcgtttctta tattgcatgg agtccagatg   1140
acaactatct tgttgcttgt ggcccagatg actgctctga gctttggctt tggaatgtac   1200
aaacaggaga actaaggaca aaaatgagcc agtctcatga agacagtttg acaagtgtgg   1260
cttggaatcc agatgggaag cgctttgtga ctggaggtca gcgtgggcag ttctatcagt   1320
gtgacttaga tggtaatctc cttgactcct gggaaggggt aagagtgcaa tgcctttggt   1380
gcttgagtga tggaaagact gttctggcat cagatacaca ccagcgaatt cggggctata   1440
acttcgagga ccttacagat aggaacatag tacaagaaga tcatcctatt atgtctttta   1500
ctatttcaaa aaatggccga ttagctttgt taaatgtagc aactcaggga gttcatttat   1560
gggacttgca agacagagtt ttagtaagaa agtatcaagg tgttacacaa gggttttata   1620
caattcattg catgttttgg aggccataat gaagacttca tcgctagtgg cagtgaagat   1680
cacaaggttt acatctggca caaacgtagt gaactgccaa ttgcggagct gacagggcac   1740
acacgtacag taaactgtgt gagctggaac ccacagattc catccatgat ggccagcgcc   1800
tcanatgatg gcactgttag aatatgggga ccagcacctt ttatagacca ccagaatatt   1860
gaagtgagaa agatgactaa ttgctctcag ttaagtgatt ctctgtggag gagggttatc   1920
ggagtagcat gtatggtttg aaaaagtata ttccctacac ttttatcttt gtggtacaga   1980
ctgtagaagg nttgccacat cttactggcg gaggaatgca gtancatgga tagttgatgg   2040
tgaatttgga canacgactt                                               2060

<210> 999
<211> 4339
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (405)
<223> n equals a,t,g, or c

<400> 999
ggcgactacc cgaggaggct gacctccagc ccgggcgccc ggttcagcgc cgccccggcc     60
ggcgccggtg cctgccaggc actcagggag gcgggggcgc agtggaggag gcggcgccat    120
cgcgaagmga gcgcctcgcc cgcactcagc cttgccaccc cgcccgcagt ccaggctgga    180
ctgggcggca tttgccgagg ctcctcggcc aggccccgtc cgcccgagcc gcgctgagac    240
ccgggcagcg gccgcgtgga gaggaggtgg cagcggcccg ggaggccgra gccaagccag    300
cgacccacca tggagacccg ctacaacctg aagagtccgg ctgttaaacg tttaatgaaa    360
gaagcggcag aattgaaaga tccaacagat cattaccatg cgcanscttt agaggataac    420
ctttttgaat ggcacttcac ggttagaggg cccccagact ccgattttga tggaggagtt    480
tatcacgggc ggatagtact gccaccagag tatcccatga aaccaccaag cattattctc    540
ctaacggcta atggtcgatt tgaagtgggc aagaaaatct gtttgagcat ctcaggccat    600
catcctgaaa cttggcagcc ttcgtggagt ataaggacag cattattagc catcattggg    660
tttatgccaa caaaaggaga gggagccata ggttctctag attacactcc tgaggaaaga    720
agagcacttg ccaaaaaatc acaagatttc tgttgtgaag gatgtggctc tgccatgaag    780
gatgtcctgt tgcctttaaa atctggaagc gattcaagcc aagctgacca agaagccaaa    840
gaactggcta ggcaaataag ctttaaggca gaagtcaatt catctggaaa gactatctct    900
gagtcagact taaaccactc tttttcacta actgatttac aagatgatat acctacaaca    960
ttccagggtg ctacggccag tacatcgtac ggactccaga attcctcagc agcatccttt   1020
catcaaccta cccaacctgt agctaagaat acctccatga gccctcgaca gcgccgggcc   1080
cagcagcaga gtcagagaag gttgtctact tcaccagatg taatccaggg ccaccagcca   1140
agagacaacc acactgatca tggtgggtca gctgtactga ttgtcatcct gactttggca   1200
ttggcagctc ttatattccg acgaatatat ctggcaaacg aatacatatt tgactttgag   1260
ttataatatg gttttgtgac ttatgagctg tgactcaact gcttcattaa acattctgca   1320
ttgggtataa tctaagaatt gtttacaaaa agattatttt gtatttaccc ttcattcctt   1380
tttttgatcc ttgtaagttt agtataaata tatctagaca ttcagactgt gtctagcagt   1440
tacgtcctgc ttaaagggac tagaagtcaa agttccttgt ctcactattt gatctgcttt   1500
gcagggaaat aacttgtttt ttctcatgtt tcatcttctt tttatgtaaa tttgtaatac   1560
tttcctatat tgccctttga aatttttgga taaaagatga tgttttaagt tccaatgagt   1620
attactagtt actcaatacc acttattgag tactctgttt ctacgtatgt agaatgtata   1680
gggatagaag agttgaaaag ggaaagcaaa actcctcaag tagcttcctt aaaatgtcat   1740
tcataggaga tgtactggaa ttgctcattc tgtgacttta tttgtgtcct aaacattctt   1800
cagtgaaaat aattttattt cagtcaaaca tttatgagga aatgagatca catctttgtc   1860
actggatgct acttgaagag ggagtacttt gtaaccactt tgatatgctg ttatcaccac   1920
cccctgccct ctgctgccat aatcacacaa atttaaaaag aaagaaaaca gtcttccata   1980
gatttttaag gaagaaaggg cccaagccag gagatcgctt ggttttcttc cagaagttaa   2040
atggggggat ctgaagattt gaatgtttgg tctgctttga aatgtatgtc ttttgggatg   2100
tattatatgc ctagctttat aatcagtata aattttaatt attccaggaa tatgcataat   2160
attgaaatat ttcatgtcct attttaatag aaaacctcag ggcccaagta acagtgatag   2220
aagttagaaa aacctttact tagaattgtc cacctagtca gagcccaaga aagaattttc   2280
agtggaaaaa tcaatatata acttagtgct agctagcgcc acagactcta gtagataata   2340
ttatcatcat aatggctggt gaaaccatat aatcacagaa aaacattgcc ttcagcatgt   2400
tcagttcgca gcactgaggg cactcttgag ggtgttgtta atgaagattt aatttttaaa   2460
tacaggtggt tccaagcttt caaataggtt atgctccaaa agtgttattt gtaagttaat   2520
ttttttacaa gtcaaacaat gttggaagtg gtatttaggt tctagatcgg tccacgaaag   2580
ttagcccata tgtatatctt gaatagtata ggggagggta ttcataaagt ccttatgtgg   2640
ttttaactaa gtgaaattat ggacaagaga aataattgta aaatcgtctt aaaggcaaat   2700
ttaattttta ctcctgttta tgggacattc gttctattaa ctgtcagaca caatttctgt   2760
tttcatctga gagccagttt tcctttattt ctacatctaa aataagaaca tattgtacac   2820
tattatataa tacagaattg tcttaaactt taataaattc gcattttaaa ggtgtttaca   2880
gattattttt tatatctgta gctgaatttg ttaaagtcta aaaagctcaa ggactttatg   2940
aagatctcat tatatgagga aaatcatagg ttaccatttt ataactctat tgccataaga   3000
aaatacactc taaaatcttg atttgaaaca tattagaaac cttgattcag tgctcagtgg   3060
tctcctagta agaagtcacc gacggtagcg tcatatgaga agaaagaaat ccccaccacc   3120
tcaacctctg ctgagattgt gtgctaggaa cagccttccc tccgtttccc ctcagtcaaa   3180
cttgagccag cctctggatc gatgtgatct tattgcatgt ttccatgggg tgtacctata   3240
ctttaagcca atcctgctgc attcactgct aagttaaata aaaagccaag aagattttgc   3300
actgtgcaga tcctttgcta tctgacttgc atctcttccc ccacctgtca gctagccacc   3360
tgcttgtttg tgttgggata ttttttagca cctgaagcac catctgaaag gggcaccatt   3420
ttcttcttcc ctttgatctc acatatgctc cctaaaaatc cttaagttgt caatctgatc   3480
cccagtgtga ggttaatgag caaaattggt ctttggggcc ctttttgtcc aagccccact   3540
gaaaggcctc ttcagaaaac tattatcttt aaagccctac tttaactcct taattccagc   3600
atacagctaa aactggatgt atattctggc aagtaaaggc tgaggactcc tctttaatcc   3660
tcagatctag ataactcatg acattttatt tgaccaacat agcacatgat gagatatcaa   3720
ggtaattaaa atagcatgct tgaaaaaaaa atacgtaatc tgtttcacct gtaactgttt   3780
aagccaataa acttttcaaa atttatgtaa tgtggggctt ttatgtagca ctttacgttt   3840
tcatgctgct tattgtttta ttctactgaa aaaaatgaat ttcaagattc tcaacttttt   3900
taatttcaaa aattgtttat tgttttgact ataggaatac aaaatttcct attttgggag   3960
aataagaact ctttttgtca tttttggcta tgaataaact ttctggtctt ttgagaccac   4020
ccatttttat agatcagaat cagaaaacag gtaaacctca ctcacacatt tggactcatt   4080
tgaacaaaaa tctaggccaa aatactgaaa agcctatgtg tttttttaat tggaagtata   4140
tgtaaggtta atgcatttag tgaacgtgac taacaaagac taatgtgcac attaacagat   4200
gtacttttta aggttttatg ggaggctgtg cattgctcaa aagctgttgg gaacgccttc   4260
tgaacagttg ccttcagaac tagtttgagc tgctcaataa aaccagtgac tttactcata   4320
aaaaaaaara aaaaaaaaa                                                4339

<210> 1000
<211> 1652
<212> DNA
<213> Homo sapiens

<400> 1000
gggcagcttc tggggacagc cacaaggagg gtaccagggg tcccccgccg ctgcctacag     60
acatgcgcca gatcagccag gactttagcg agctaagcac ccagctgacg ggtgtggccc    120
gggacctgca ggaggagatg ctgccaggaa gctctgagga ttggctggaa cccccagggg    180
cagttgggcg accagccaca gagcccccca gggagggcac aaccgagggg gatgaggagg    240
atgccacgga ggcatggcgc ctgcaccaga agcatgtctt tgtgctgagt gaggcaggga    300
agcctgtgta ctcccgctat gggtctgagg aggcactttc cagcactatg ggtgttatgg    360
tggccctggt gtccttcctg gaggcagaca agaacgccat ccgctccatc catgcagatg    420
gctacaaggt agtattcgtg cgccggagcc cgctggtgct agtggcggtg gctcgtacgc    480
ggcagtcggc acaagagctg gcgcaggagc tgctctacat ctactaccag atcctaagcc    540
ttcttaccgg tgcgcagctg agccacatct tccagcagaa gcagaactat gatttgcggc    600
gcctactctc gggctcagag cgcatcaccg acaacctgct gcagctcatg gcacgagacc    660
ccagcttcct gatgggggcg gcacggtgcc tgcccctggc ggcggccgtg cgcgacactg    720
tgagcgccag cctgcagcag gcgcgtgcgc gcagcctggt cttctccatc ctgctggccc    780
gcaaccagct cgtggcactc gtgcgccgaa aggaccaatt tctgcacccc atcgacctgc    840
acctgctctt caacctcatt agttcctcct cgtcctttcg cgagggcgag gcctggacgc    900
ccgtgtgcct gcccaaattc aacgcagccg gcttcttcca cgcacacatc tcttacctag    960
agcctgacac tgacctctgc ctgctgcttg tctccactga ccgtgaggac ttctttgcag   1020
tctctgactg ccgccgccgc ttccaggagc gccttcgcaa gcgcggagcc cacctggccc   1080
tgcgagaggc actgcgcaca ccctactaca gcgttgccca agtgggcatc cctgacctgc   1140
gtcacttcct ctataagtca aagagctcgg gactcttcac cagccctgag attgaggccc   1200
catacaccag tgaagaggag caggagcggc tgctgggcct ctaccagtac ttgcacagtc   1260
gtgcccacaa tgcctctcgc ccactcaaga ccatttacta cacgggcccc aacgagaacc   1320
tcctggcctg ggtgacaggc gcctttgagc tctacatgtg ttacagcccc ctggggacca   1380
aggcgtcagc cgtcagtgcc atccataagc tgatgcgctg gatccgcaaa gaggaagacc   1440
gcctcttcat tctcacgccc ctcacctatt gatgggaatg tgtgcgggct cagccttcct   1500
ggacacacta ggtgtgggaa gccataggag cctccagatg ggggctggcc tctcttgccc   1560
agccagcggg cagggactgt gggttggtga atgcattaaa gtgctttggg gaagacaaaa   1620
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa                                 1652

<210> 1001
<211> 2045
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (975)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1255)
<223> n equals a,t,g, or c

<400> 1001
ggaatctctg gcaggtctgt gtgttctgtc acttgctcgc ccgagcagtg gctttgctgg     60
tcatcccggt cgtcctgtta cttactgttc ttctacgtcc acttgattct agtcttccgc    120
tctgggcccc acgaccaaat catgtccagt gccttccagg ccagcttaga gggaggacta    180
gctcggatca cycagggtca gccactggag gtggcctttg ggtcccagrt cactctgagg    240
aacgtctttg ggaaacctgt gccctgctgg cttcattccc accaggacac ctaccccatg    300
atatatgaga acggcgaggc agctcccacc agcaacaggt gacctgttac cccttcaaag    360
acgtcaataa ctggtggatt gtaaaggatc ccaggaggca ccagctggtg gtgagcagcc    420
ctccgagacc tgtgaggcac ggggacatgg tgcagctggt ccacggcatg accacccgct    480
ccctgaacac gcatgatgtt gcagcccccc tgagccccca ttcacaggag gtctcctgct    540
acattgacta taacatctcc atgcccgccc agaacctctg gagactggaa attgtgaaca    600
gaggatctga cacagacgtc tggaagacca tcctctcaga ggtccgcttt gtgcacgtga    660
acacttccgc tgtcttaaag ctgagcgggg ctcacctccc tgactggggg tatcggcaac    720
tggagatcgt cggggagaag ctgtcccggg gctaccacgg gagcacggtg tggaacgtgg    780
aggagcaccg atacggcgcg agcaggagca gagggagcgg gaacgggagc tgcactcacc    840
tgcgcaggtg gacgtcagca ggaacctcag cttcatggcg agattctcgg agctgcagtg    900
gaggatgctg gcgctgagaa gtgatgactc ggaacacaag tacagctcca gcccactgga    960
gtgggtcacc ctggnacacc aatattgcct actggctgca ccccaggacc agcgctcaga   1020
tccacctact tggaaacata gtgatctggg tttcgggcag cctcgctctg gccatctacg   1080
ccctgctgtc cttgtggtac ctgctccgac ggcgaagaaa tgtccatgac ctccctcagg   1140
atgcctggct gcgctgggtg ctggctgggg cgctgtgtgc cggtggctgg gcagtgaact   1200
acctcccgtt cttcctgatg gagaagacac tcttcctcta ccactacctg cccgnactgc   1260
accttccaaa tccttctgct ccctgtggtc ctgcagcaca tcagcgacca cctgtgcagg   1320
tcccagctcc agaggagatc ttcagcgccc tggtggtggc ctggtactcc tccgcgtgcc   1380
acgtgtccaa cacgctgcgc ccactcacct acggggacaa gtcactctcg ccacatgaac   1440
tcaaggccct tcgctggaaa gacagctggg acatcttgat ccgaaaacac tagaacaaga   1500
gtgtggcaaa gaacacccgt gctggggtcg ggacgaggtt gaagggtctt ggtcaataca   1560
cagggagtat ttcagaggcc agcgtaggag tcatcgacaa cgaaaagccg agaacccagg   1620
gccagcagtg gagcctcagc agaccagggc ctggtccttg ctaattgctg cagggtggag   1680
tttgatctgg cagacccgat cctccttcat gaacacccag caacctgagc aagtcccggc   1740
cctgccctca gcgagcccgg caggcgtccc gggacagctc agtgttggag ggccacctga   1800
accacgagcc agggctgggg cttgcatgtc attgtctatg acagcgtcaa gactggccct   1860
tggcaccgtg ctgtgtggaa accctcccct ctgagactcc actgagacgt ggctgagtga   1920
aatcttcctc gtcagtggtc aaggtgtgtc atccatacag ctccatgcct ttgtcttttt   1980
taaatgtaat taaaaaagga accaactggc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2040
aaaaa                                                               2045

<210> 1002
<211> 1239
<212> DNA
<213> Homo sapiens

<400> 1002
ctactttttt cttaccactt aatagaagaa cctgtcccta gaggcgactt cattgctatg     60
gatgtggagt ctctgaactc ttaataggat gcagcctcac atacataatg tcacccattt    120
tatgttgatg aaaacattac aagttttcat cattgggtat gtgttgatgt tcacagacag    180
tacttgggcc cattaggttt tcgcgtctgg tcttagagca tgtgtattca tctcagcgtg    240
aatacctcag ccagtcttat gaataggagg ctatgtatgg gcagggaata gattagatta    300
gaacactcgc acaagatgac cacatataga agcagaaagc cccaaattcc ctgggaactg    360
ttttttctct agtagctgaa tataaggaaa tatgtctaat ggacaccagt taatactttt    420
taaaactact ctttaaaaaa aaaatacgtt ccccttggtt aactgatttt ttaatccagg    480
gtggacattt tttcaacctt tattaaaaag acaaataaac tattttgtag aagatcagac    540
tcctacttaa ctggaagaga aatgtctatt aaatgtctct cctctttctc tgggtcaaga    600
ccatgtaatt ttatgcttca gagatgaaga tactgtttgt ttacaaagag tttagttttt    660
aagacatcca aaactctatg ctagagcaaa aatcaaatag caaaggacac tagccagaaa    720
atacagtgtg tgtgtgtgca cctgtgtgcc tgctgaacaa cttgacagtg taacagataa    780
ggtaactgaa gatggtggat atttgaattg tattagctta atgtctacat atctttggcc    840
aaaactctat tgtcatatta gaaacatgtt atctttttca tgtttattag taatttattt    900
ttgattcttt gttttctttt tcgtccaact aaaacaactg taatgtactt gatacattta    960
tatcaagttc taaagtattt agacaaatcc aaatactttg tttttagttt tttcctcctt   1020
tccatcctgt taaccacagt gaaacgctgc agtattttga tttggtcagt gctacggagg   1080
aagaccatga aagctgaatt ggtctgtgcc acccagagta aacctcttct cttcttctgg   1140
aaagatggcg tgatgttttt caaggattct aataaatatc ccgcagtcat ctcctgaaaa   1200
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agggcggcc                          1239

<210> 1003
<211> 2012
<212> DNA
<213> Homo sapiens

<400> 1003
ggcacgaggc gcccttcctc ttctgtgcgc tcgggctcct ggtcccggct ccccggttac     60
cggggcgcga gtatgaccac aatggcggcc gccaccctgc tgcgcgcgac gccccacttc    120
agcggtctcg ccgccggccg gaccttcctg ctgcagggtc tgttgcggct gctgaaagcc    180
ccggcattgc ctctcttgtg ccgcggcctg gccgtggagg ccaagaagac ttacgtgcgc    240
gacaagccac atgtgaatgt gggtaccatc ggccatgtgg accacgggaa gaccacgctg    300
actgcagcca tcacgaagat tctagctgag ggaggtgggg ctaagttcaa gaagtacgag    360
gagattgaca atgccccgga ggagcgagct cggggtatca ccatcaatgc ggctcatgtg    420
gagtatagca ctgccgcccg ccactacgcc cacacagact gcccgggtca tgcagattat    480
gttaagaata tgatcacagg cactgcaccc ctcgacggct gcatcctggt ggtagcagcc    540
aatgacggcc ccatgcccca gacccgagag cacttattac tggccagaca gattggggtg    600
gagcatgtgg tggtgtatgt gaacaaggct gacgctgtcc aggactctga gatggtggaa    660
ctggtggaac tggagatccg ggagctgctc accgagtttg gctataaagg ggaggagacc    720
ccagtcatcg taggctctgc tctctgtgcc cttgagggtc gggaccctga gttaggcctg    780
aagtctgtgc agaagctact ggatgctgtg gacacttaca tcccagtgcc cgcccgggac    840
ctggagaagc ctttcctgct gcctgtggag gcggtgtact ccgtccctgg ccgtggcacc    900
gtggtgacag gtacactaga gcgtggcatt ttaaagaagg gagacgagtg tgagctccta    960
ggacatagca agaacatccg cactgtggtg acaggcattg agatgttcca caagagcctg   1020
gagagggccg aggccggaga taacctcggg gccctggtcc gaggcttgaa gcgggaggac   1080
ttgcggcggg gcctggtcat ggtcaagcca ggttccatca agccccacca gaaggtggag   1140
gcccaggttt acatcctcag caaggaggaa ggtggccgcc acaagccctt tgtgtcccac   1200
ttcatgcctg tcatgttctc cctgacttgg gacatggcct gtcggattat cctgccccca   1260
gagaaggagc ttgccatgcc cggggaggac ctgaagttca acctaatctt gcggcagcca   1320
atgatcttag agaaaggcca gcgtttcacc ctgcgagatg gcaaccggac tattggcacc   1380
ggtctagtca ccaacacgct ggccatgact gaggaggaga agaatatcaa atggggttga   1440
gtgtgcagat ctctgctcag cttcccttgc gtttaaggcc tgccctagcc agggctccct   1500
cctgcttcca gtaccctctc atggcatagg ctgcaaccca gcagagggca gctagatgga   1560
catttcccct gctcggaagg gttggcctgc ctggctgggg aggtcagtaa actttgaata   1620
gtaagccagc ctgtgtcctg tgtcctttgt gcaaattgga gaggataggg gaggacaaaa   1680
agggtgttga accccagaca gatggggagc ttgtgagatc ccagagcagt tttaacggak   1740
aaatcaagtc cagtgagctt agtgattgcc tagacacagt aggatgccgt tattcagcct   1800
cctgggagat agtgggaaag aatgttctat cgctctggag ccagcatggc ttcagctcag   1860
gtgccaaacc catcttgttt cctcggaata ctaagtgaat gtctagcatc cattcacatt   1920
ctgtgggaac agggactgga caggcatacc tcagatgctg taggtttgct tccagactac   1980
cacaataaag caggtcacaa atttaaaaaa aa                                 2012

<210> 1004
<211> 1800
<212> DNA
<213> Homo sapiens

<400> 1004
cgggactggg ctgcggcggt tagtcctctc ccggccgccg tcgcctccga catattgccc     60
gcagagctgc ggcggcgaag ggagagcacc ggggggagga gatgggagga cgaagaggtc    120
ccaacaggac atcttactgt cgaaatccgc tctgtgagcc gggatcctcg gggggctcta    180
gtggaagcca cacttccagt gcatcggtga ccagtgttcg ttcccgcacc aggagcagtt    240
ctggaacagg cctctccagc cctcctctgg ccacccaaac tgttgtgcct ctacagcact    300
gcaagatccc cgagctgcca gtccaggcca gcattctgtt tgagttgcag ctcttcttct    360
gccagctcat agcactcttc gtccactaca tcaacatcta caagacagtg tggtggtatc    420
caccttccca cccaccctcc cacacctccc tgaacttcca tctgatcgay ttcaacttgc    480
tgatggtgac caccatcgtt ctgggccgcc gcttcattgg gtccatcgtg aaggaggcct    540
ctcagagggg gaaggtctcc ctctttcgct ccatcctgct gttcctcact cgcttcaccg    600
ttctcacggc aacaggctgg agtctgtgcc gatccctcat ccacctcttc aggacctact    660
ccttcctgaa cctcctgttc ctctgctatc cgtttgggat gtacattccg ttcctgcagc    720
tgaattgcga cctccgcaag acaagcctct tcaaccacat ggcctccatg gggccccggg    780
aggcggtcag tggcctggca aagagccggg actacctcct gacactgcgg gagacgtgga    840
agcagcacac aagacagctg tatggcccgg acgccatgcc cacccatgcc tgctgcctgt    900
crcccagcct catccgcagt gaggtggagt tcctcaagat ggacttcaac tggcgcatga    960
aggaagtgct cgtcagctcc atgctgagcg cctactatgt ggcctttgtg cctgtctggt   1020
tcgtgaagaa cacacattac tatgacaagc gctggtcctg tgaactcttc ctgctggtgt   1080
ccatcagcac ctccgtgatc ctcatgcagc acctgctgcc tgccagctac tgtgacctgc   1140
tgcacaaggc cgccgcccat ctgggctgtt ggcagaaggt ggacccagcg ctgtgctcca   1200
acgtgctgca gcacccgtgg actgaagaat gcatgtggcc gcagggcgtg ctggtgaagc   1260
acagcaagaa cgtctacaaa gccgtaggcc amwacaamgt ggctatcccc tctgacgtct   1320
cccacttccg cttccatttc tttttcagca aacccctgcg gatcctcaac atcctcctgc   1380
tgctggaggg cgctgtcatt gtctatcagc tgtactccct aatgtcctct gaaaagtggc   1440
accagaccat ctcgctggcc ctcatcctct tcagcaacta ctatgccttc ttcaagctgc   1500
tccgggaccg cttggtattg ggcaaggcct actcatactc tgctagcccc cagagagacc   1560
tggaccaccg tttctcctga gccctggggt cacctcaggg acagcgtcca ggcttcagcc   1620
aagggctccc tggcaagggg ctgttgggta gaagtggtgg tgggggggac aaaagacaaa   1680
aaaatccacc agagctttgt atttttgtta cgtactgttt ctttgataat tgatgtgata   1740
aggaaaaaag tcctattttt atactcccaa maaaaaaaaa aaaaaaagcg gccgaaagct   1800

<210> 1005
<211> 695
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (638)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (659)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (673)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (687)
<223> n equals a,t,g, or c

<400> 1005
gtcagacagg tggagccgcc ggggcaggag tctcaaagag ccaggctcca ggagaggaag     60
ggctctgcga gaggagagag gagagcgctg gagaggagag gctggagagt ccttagccag    120
gatggaggct gttgtgaact tgtaccaaga ggtgatgaag cacgcagatc cccggatcca    180
gggctaccct ctgatggggt cccccttgct aatgacctcc attctcctga cctacgtgta    240
cttcgttctc tcacttgggc ctcgcatcat ggctaatcgg aagcccttcc agctccgtgg    300
cttcatgatt gtctacaact tctcactggt ggcactctcc ctctacattg tctatgagtt    360
cctgatgtcg ggctggctga gcacctatac ctggcgctgt gaccctgtgg actattccaa    420
cagccctgag gcacttagga tggttcgggt ggcctggctc ttcctcttct ccaagttcat    480
tgagctgatg gacacagtga tctttattct ccgaaagaaa gacgggcagg tgaccttcct    540
acatgtcttc atcactctgt gcttcctgga rctggtggtg gggggtaaag attgccccgg    600
gaggaatggg ctctttccat gccakgataa ctctccgngc atgtcataat ggacctggnc    660
tacggattat tgnctttggc ctttggnaca acctt                               695

<210> 1006
<211> 922
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (849)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (893)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (909)
<223> n equals a,t,g, or c

<400> 1006
gtancngaca gtcacggtcg gattcccggg tcgacccacg cgtccggtcc gcagtgacta     60
cactcatggc aggtcccctg tggcggaccg cagcatttgt gcagagacac aggacaggcc    120
tcttggtggg ttcctgtgca ggcctgtttg gagttccagt ctcgtaccac ctcttcccgg    180
atcccgtggt ccaatggctc taccagtact ggcctcaggg ccasccagct ccgctccctc    240
cacagctgca gagcctcttc caagaggtgc tacaggacat aggtgttcct tcaggccatt    300
gctacaagcc cttcaccacc ttcaccttcc agcctgtgag tgcaggcttc ccaagactcc    360
ctgctggggc tgtggtgggc atccctgcca gtttcttggg agacctagtg atcaacacta    420
accatcccgt ggtcatacat gggcatacag tggamtkgcg gagccagcar gcgcccggct    480
gagagcttcc ctgaccttgt cccgtgaagc ccagaagttc gccttggcca gggaagtggt    540
gtacctggaa agcagtacca ctgccgtgca cgccctgctg gccccagctt gcctggcagg    600
gacctgggca ctgggcgtgg gtgccaagta caccctgggg ctccatgcag gccccatgaa    660
tttacgggct gccttcagct tggtggcagc agtggcaggc tttgtggcct acgccttctc    720
ccaggattct ctcactcatg ccgtggagtc ctggctggac cgccgcacgg cytccctctc    780
tgcagcctat gcctgtggtg gagtggagtt ctatgagaag cttctgtcgg gcaacctggc    840
cctgcgcant ctctttgggc aaaagaaggg ggagaagctg tatacaccca acngggaaca    900
tcgtccccna gacacttgtt cc                                             922

<210> 1007
<211> 1571
<212> DNA
<213> Homo sapiens

<400> 1007
ggaacctcat caacgctgac ttctgcgtgg cctctgtctg cgtggccttt ggggcagttc     60
tgggtaaagt cagccccatt cagctgctca tcatgacttt cttccaagtg accctcttcg    120
ctgtgaatga gttcattctc cttaacctgc taaaggtgaa ggatgcagga ggctccatga    180
ccatccacac atttggcgcc tactttgggc tcacagtgac ccggatcctc taccgacgca    240
acctagagca gagcaaggag agacagaatt ctgtgtacca gtcggacctc tttgccatga    300
ttggcaccct cttcctgtgg atgtactggc ccagcttcaa ctcagccata tcctaccatg    360
gggacagcca gcaccgagcc gccatcaaca cctactgctc cttggcagcc tgcgtgctta    420
cctcggtggc aatatccagt gccctgcaca agaagggcaa gctggacatg gtgcacatcc    480
agaatgccac gctcgcagga ggggtggccg tgggtaccgc tgctgagatg atgctcatgc    540
cttacggtgc cctcatcatc ggcttcgtct gcggcatcat ctccaccctg ggttttgtat    600
acctgacccc attcctggag tcccggctgc acatccagga cacatgtggc attaacaatc    660
tgcatggcat tcctggcatc ataggcggca tcgtgggtgc tgtgacagcg gcctccgcca    720
gccttgaagt ctatggaaaa gaagggcttg tccattcctt tgactttcaa ggtttcaacg    780
gggactggac cgcaagaaca cagggaaagt tccagattta tggtctcttg gtgaccctgg    840
ccatggccct gatgggtggc atcattgtgg ggctcatttt gagattacca ttctggggac    900
aaccttcaga tgagaactgc tttgaggatg cggtytactg ggagatgcct gaagggaaca    960
gcactgtyta catccctgag gaccccacct tcaagccctc aggaccctca gtaccctcag   1020
tacccatggt gtccccacta cccatggctt cctcggtacc cttggtaccc taggctccca   1080
gggcaggtga ggagcaggct ccacagactg tcctggggcc cagaggagct ggtgctgacc   1140
tagctaggga tgcaagagtg agcaagcagc acccccacct gctggcttgg cctcaaggtg   1200
cctccacccc tgccctcccc ttcatcccag ggggtctgmc tgagaatgga gaaggagaag   1260
ctacaaagtg ggcatccaag ccgggttctg gctgcagaag ttctgcctct gcctggggtc   1320
ttggccacat tggagaaaaa caggctcaaa gtggggctgg gacctggtgg gtgaacctga   1380
gctctcccag gagacaactt agctgccagt caccacctat gaggctcttc taccccgtgc   1440
ctgcacctcg gccagcatct cctatgctcc ctggtccccc agacctctct gtgttgtgtg   1500
cgtggcagcc tccaggaata aacattcttg ttgtcctttg taaaaaaaaa aaaaaaaaaa   1560
aaaaaaaaaa a                                                        1571

<210> 1008
<211> 2222
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2212)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2214)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2215)
<223> n equals a,t,g, or c

<400> 1008
gncccgaggc tgcgtggtgg agggcaaccc cgtgctggca ggatcctgcg actcaacgtg     60
cagccatctg gtggtgccca tcctgctcct ggtcagcctg ggctcggccc tggcctgtct    120
cacccacaca ccctccttca tgctcatcct aagaggagtg aagaaagaag acaagacttt    180
ggctgtgggc atccagttca tgttcctgag gattttggcc tggatgccca gccccgtgat    240
ccacggcagc gccatcgaca ccacctgtgt gcactgggcc ctgagctgtg ggcgtcgagc    300
tgtctgtcgc tactacaata atgacctgct ccgaaaccgg ttcatcggcc tccagttctt    360
cttcaaaaca ggttctgtga tctgcttcgc cttagttttg gctgtcctga ggcagcagga    420
caaagaggca aggaccaaag agagcagatc cagccctgcc gtagagcagc aattgctagt    480
gtcggggcca gggaagaagc cagaggattc ccgagtgtga gctgtcttgg ggccccacct    540
ggccaagagt agcagccaca gcagtacctc ctctgagtcc tttgcccaag attgggtgtc    600
aagagccctg tgttccattc tggctcctcc actaaattgc tgtgtgactt caggcaagac    660
attgatcctc tctcagcctt tgcttgctag tctgaaccaa agagttgttt gggcatttgc    720
tgtgttggcc atttctggag caagagggtc ttcttcctcc ttcccccagc cagccagctg    780
tcctggggcc aggctttcct gggtggaaag aagtatacct ttccctgggg ccctaggata    840
gcaaagtgag ccatagtggg ccaggctgcc ctccatgctg ggccccagcc caggtctgca    900
ctcgcctgga tcaccttctt tgagccttag ccatctcctg tcaggtagga atgaacttgc    960
cagccttcag gctcgttcag ctatgaccat ctgtgcggtc agggtacact cagctctcct   1020
ccccaactcc agcagccttt aagaagtgtc cctttggcgc cccctggagg cagagcactg   1080
agctggaccc tgggtagact cccacaggga ggacggagct ggcctcagga gtgggacacc   1140
cagacttggc agggccttca agaggcctgt gtgggggccc caggaatcct tagctgaagc   1200
ggggagactc actctccatc tcaggaaatt ctagcccttg ccctcaggga gccacggttg   1260
agggtgaggc ccaacacctg ccttagggcc ctgggtgggc aagtctgggc cctggggtag   1320
ggagggagac tcaggcccac acttgggtat tttctaattt cagacaaaca cacactcagc   1380
gcgcactcac tgattcctac acattgccaa gatttcacac atgtgaccag gggccaccaa   1440
agtccctgtg acctttgtga ctaggatcct aatttctcta ttttctcctg ggtgcctggg   1500
tctgtgtcac ctggggcagt gtggataatg tttagttctg tgacactgtt ttttgggggt   1560
ggcacctggt tctccgatgc ctgggctggt gtcaggccca ggactgtagt gctgggagca   1620
gtaaagctca gctctgtgta atgagtgatg ctatggcttg ctcgtgtctt atgatccaat   1680
ccttttctac atcagccctt gttttgtttt atggctagtc ttatctggcc tggttatttc   1740
cttgcgggga ggagagggtt tgctaatctg ctcccagccc aacctattac caccccacct   1800
cgctgggacc tactgctcgg gaggcagcag acagggagcc accagcagtg gcttcctggc   1860
cctgtgctgg gggtgggggg aagctggggg cacatgtggc ccttgccttc tgagcagctc   1920
ccagtgccag ggctttgaga ctttcccaca tgataaaaga aaagggaggt acagaagttc   1980
caattccctt tttattttgc tggttggtat ctgtaaatgt ttaataaata tctgagcatg   2040
tatctatcaa cgccaagaat ttcaaagtct ccttcaacaa tatgaggctt ttaggatgtt   2100
tatattcctt catccctctt gtttcccagg ttttgcaggg aaaaaaagtc tggaattata   2160
gatacagctt attattaaat ttgttcttgc ataaaaaaaa aaaaaaaraa cncnnggggg   2220
gg                                                                  2222

<210> 1009
<211> 2050
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2048)
<223> n equals a,t,g, or c

<400> 1009
gagggcagag gaggagagtc gcgggcggcc gcttgggcgc acttnccggg tcaccttgtc     60
ccggaggaga aatggcttcc ctgaggcaag tgtaacctac attcccagcc caccagcctg    120
acgcccagcc agggagagag taccatggat ggcatcattg aacagaagag catgctggtg    180
cacagtaaaa tcagtgatgc tggcaagagg aatggtttaa ttaacaccag aaacttgatg    240
gccgagagca gagatggtct ggtgtctgtt tacccagcgc cccagtacca gagccaccgg    300
gtgggggcca gcacagtgcc ggccagcctg gacagcagca ggagtgagcc gatgcagcag    360
ctgctggacc ccaacaccct gcagcagtca gtggagtccc gctaccggcc caacatcatc    420
ctctattcag agggcgtgct gcgctcctgg ggggacggtg tggccgccga ctgctgcgag    480
accaccttca tcgaggaccg gtcgcccacc aaagacagcc tcgagtaccc ggatgggaag    540
ttcattgacc tctcagctga tgacataaaa atccacaccc tgtcctacga tgtggaggag    600
gaggaggagt tccaggagct ggagagcgac tactcaagcg acacagagag tgaggacaat    660
ttcctcatga tgcccccgcg ggaccacctg ggcctcagtg tcttctccat gctctgctgc    720
ttctggcctc tgggmatcgc agccttctac ttgtcccatg agaccaacaa agccgtggcc    780
aagggggact tgcaccaggc cagcaccagc tcccggcggg ccctattcct ggcagtgctg    840
tccatcacca ttgggactgg cgtctatgtg ggcgtggccg tggccctcat cgcctacctc    900
tccaagaaca accacctgtg agcttcctgc gaatggaggg ggagcacccg gggccaggtc    960
tgtgtggacg tggaggaagc aggcataccg catgatgctg tacagtacaa atgattgcca   1020
aatgatgcca cgargccctg ggatttccta cccatggatt tattttgttt ttatccttta   1080
atttcatgtt cacagcactg tgtagagcac cagacagacg ggcactgcta atccttccaa   1140
aggaaagctc caaagatccc agcccgcaag gctgtctctg gatggattct ggtggatgaa   1200
tggcaacgcg gctctctgca gcctgccagt gcccagagtg ccaccgcatt agcaatatac   1260
aaacagtcca aaaaagtgtt tattttttat ggaatacggt gcaataggca gaggacaagg   1320
gacacatcac tcttctgtct gtggccctgc tggagtcctt tgtgcccccc ggagtccaca   1380
cgccttccct gcaagacgag aatggggctg ggaagaaaga ggcaacacca cggctggcag   1440
gagccccgct gcactgctct gcagacccat tggcctgacc ctgagaagca gagccagcaa   1500
agcccgggac ctgcccctct ttctttccct tcacaccacc ccagcctcag gatgtcaagc   1560
cacctccgga acgtgtctac actccacagc taccccgcag caatacgcac tcttgggacc   1620
tcgctgatct aggatgggga ggcaggccac cgcccctccc aagactcctc aagaaagagc   1680
cccgcggttg ctccggaaac tcgaggcact gcagctatgg gcactgcctc agcctaaaga   1740
cacaggggcg cctcccaatc accgcgctgg cggatgctca ccccgtcata agcagaaact   1800
agtgatcctg gaaatgagat gggccttact ctgtcgacta aatgaatagc tattttcttg   1860
tcatttttta aagtgcaact cttgcttcat gctgcttaag ttaccagatg aatgctgaga   1920
aataagtaat cacagacatt ttaataccat ttcattgctg ttttacgagt gttcattact   1980
taacaaaaaa ttatctttta aaaaaaaaaa aaaaaaccyc gggggggscc cggtacccaa   2040
ttcgcccnaa                                                          2050

<210> 1010
<211> 3217
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (45)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (68)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3200)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3204)
<223> n equals a,t,g, or c

<400> 1010
acccaattgc ttattttgga aaattagggg ttcaagggan tggtnggccc cagacaaccc     60
acccaggncc caaaagtgct ttcgaaagct tccccagacg gctggtaact gtggtagagg    120
aaaaggaact ggtgcggcgg cggcggcagc agcggggagc tgccagaccc tagtgcctgg    180
ggtctctgag actagtgcca gcccgggwag cccgtctgtc cgcagcatgt cagggccaga    240
atcctcccct cccattggtg ggccctgtga agctgctcct tcatcctcac tgcccactcc    300
accccagcag cccttcattg ctcgccgtca cattgagctg ggggtgactg gtggtggcag    360
ccccgagaat ggagacggag cactgctcgc catcacccca cctgctgtga aacgtcggag    420
ggggaggccc cccaagmaga acaggtctcc agcagatgct ggragaggwg tkgatkaggc    480
accctcatcc accttgaagg gaaaaaccaa tggggctgam ccagtccctg ggcctgagac    540
cctaattgtt gcagatcctg tcctggaacc acagcttatt cctgggcccc agcctcttgg    600
accccagcca gttcacagac ccaatcccct cctgtcacct gtggagaaaa gaaggcgagg    660
acgaccccct aaagcacgag atttgcccat ccctgggacc atttcctctg caggggatgg    720
caactccgaa agtcggacac agccaccccc acacccatca cccctaaccc cactcccacc    780
actgctagtt tgtcccactg ctactgttgc caacactgtc accactgtca ccatttcaac    840
gtccccaccc aaacggaaga ggggccgacc tcccaagaat cctccatcac ctcggcccag    900
ccagctcccc gtcttggacc gtgacagcac ttctgttctc gagagctgtg gattggggag    960
gcgacggcaa ccccagggcc aaggggagag tgagggtagt tcctctgatg aggatggaag   1020
ccgccccctc acccgcctgg cccgccttcg gcttgaagca gaaggaatgc gaggacggaa   1080
gagtggaggg tccatggtgg tggctgtaat tcaggatgac ctggacttag cagatagcgg   1140
gccaggcggg ttggaattga caccacctgt ggtctcacta accccaaaac tgcgctcgac   1200
ccggctgcgt ccagggtctc tagtcccccc actagagact gagaagttgc ctcgcaaacg   1260
agcaggggcc ccagttggtg ggagtcctgg gctggcaaag cggggccgcc tacagccccc   1320
aagtcccctg gggcctgagg gttcagtaga ggagtctgag gctgaagctc aggwgargag   1380
gaggaagggg atgggacccc acgccgacgt cctggccccc gccggcttgt tgggaccacc   1440
aaccaagggg accagcgcat cctgcgcagc agcgcccctc cctccctggc tggccctgct   1500
gttagtcaca gaggccgcaa caagacgtga gtgggctgcc cctccaccta ggctttccac   1560
cgtggccact ccctccatga ccaggcctga ctctgttaac cactacttga agtcttgagg   1620
gggaaagcct ccagggagac ataggggcct tctcccttct tcccaccaaa gtagggggta   1680
ggcaactggt tgtcatggaa atggggatca tcacagtccc cttccccttc accccacgtg   1740
gctgggcagt gttaagggtg gcaagatagt ctctgtcccc acccccttgt acttgattcc   1800
ccagctgtct ttcacacagc cccccaccct taggggaagg gggaggggct tctctacaat   1860
gaggtttttt tctttttttt tttttttaag aagaaaaaat aataaactta gtttctgtat   1920
gagcatccgc gtaaggaggc ttctgatttt ctggtctggt ggagggttgg gtgggaactt   1980
gggcatcgtt tttctcctcc ctcttgttct tgcaaagatc ctagcacctg atctctagcc   2040
caggactata tgttccaggc agaaatctac ccaagaagag ggaagattgg tgaatttgat   2100
gtggtagggt gcctttcccc agtcagtttg aagtcacaga tatccttttc ctctcatttc   2160
ttttccctcg gttcctagac gttcctcgga gctctttgat gcctcagacc tttccctttt   2220
atccctcttg ctcaggtgct tcctttcaca actttttcca gagggcaggc gtcctagctc   2280
cagttgctcc atcccttggg ccctcccctg ctcttcatct agccaaactg gtttgagtca   2340
gccacacccc ttcccagctc cctgggctct tcacgtggtg gctggccact caaccccacc   2400
cctgggcttg gcttggagcc ctgagtcagc tccatcacca cccaagccaa accaaagctg   2460
aggcaggagc cgaaactcag agtccttcaa ggcctatagc caggtgatgg aggacgagga   2520
gaaggcagtg gagatcttgg gcaacacgga agctgctcat cctccatccc ccatccgctg   2580
ctgctggctc cgcctccgct gcttggcagc tactagcatt atctgtggct gctcttgcct   2640
gggagtcatg gctctggtgt ttgccatcaa ggcggaagag cggcataaag caggccggtc   2700
cgaggaggca gtgcgctggg gggcccgggc ccggaaactc atcctggcca gctttgctgt   2760
ctggcttgct gtcctcattc tgggtcccct gctgctgtgg ttgctctcct acgccatcgc   2820
tcaggctgag tgaccctgga tggcctctgc tgagagccag ccgagacctc ctggatcctg   2880
caatgcggca ttgctaaggt cctgtgacag cagtggttgg aaggatcctg gttggaagga   2940
tggggactct ctcaaggggc tttggaagag ctcttctagc cctttataaa aggagggcag   3000
cagctgagac tgatgagagg agggcagcct gctctgttct ttcagggccc cccaccccca   3060
tctcccctac cctagcccac cctagggcct ctacccagcg ggaggggttg aagaccaggc   3120
ctggttttat tagaattcat tttgtaataa aagccttttt tagtggtgaa aaaaaaaaaa   3180
aaaaaaaaaa aaaaaaaaan cccngggggg gggcccg                            3217

<210> 1011
<211> 560
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (556)
<223> n equals a,t,g, or c

<400> 1011
gtcttggagc tggctttggg aaaggagaaa cttgcagtca gaagcccagt gtcctatgta     60
tgcaggaagc tgtgctctag caatagacag tgttggtaat ggttgtgctg tacggcgttt    120
ggggtggccc catgttccat gctcagctga ccggatgcca actcagatga aaagaattca    180
tggctctggg caccccgtga gcagtgcttg ccatggctgg gagtttgtcg ggattgaacc    240
aaacctagtg cttcaaagct cctgggacac ctccagtgtc cagcacacat tctcatacat    300
actgccccta atttctaaag tccctaaagc actacattct gtaaccttgt ttcttttact    360
ccattcccag attagttatg caaaattcaa ctgcgttcta cttttagaag tgtttagggt    420
ctttattttc tgttgaccct tcatctggaa agattctctt cccttgttag gtacaatcam    480
tggccccccc cctttttttt tgagaggggt ctgctawgtt gccaggckgg tctaaagcck    540
gggytcaagc aacctnccgg                                                560

<210> 1012
<211> 2786
<212> DNA
<213> Homo sapiens

<400> 1012
ggtggtcggc ggcggcggcg gcggcggcgg cggcacagag ccggtggtgg agccgccgag     60
gagggtcacg cagcacaatg ccagctctgc ccctggacca actccagatc acccacaagg    120
acccgaagac aggaaagctg aggacttcac cagcgctgca ccccgagcag aaggcagacc    180
ggtattttgt gttatacaaa ccgcccccta aagacaacat tcccgcccta gtggaggagt    240
acctggaacg cgccaccttc gtagccaatg acctcgactg gctcctggcc ttgcctcacg    300
ataaattctg gtgccaggtg atctttgacg agactctaca gaagtgcctg gactcctacc    360
tgcgctatgt cccccgcaaa ttcgacgagg gggtggcctc agcccctgag gttgttgaca    420
tgcagaagcg cctccatcga agtgtttttc tcaccttcct ccgcatgtcc actcacaagg    480
aatccaaaga tcacttcatt tccccttctg cgtttggaga aatcctctac aataacttcc    540
tctttgacat tccaaagatc ctggacctct gcgtgctctt tggaaaaggc aactcaccac    600
tgctccagaa gatgatagga aacatcttta cacagcagcc aagttactac agtgacctgg    660
atgaaaccct gcctaccatc cttcaggtct tcagcaatat cctccagcac tgtggtttgc    720
aaggggacgg ggccaatacc acaccccaga agcttgagga gaggggccga ttgaccccca    780
gtgacatgcc tctcctggaa ttaaaggaca ttgttctcta cctttgtgat acctgcacca    840
cactttgggc ctttctggat atcttccctt tggcttgcca gaccttccag aagcacgact    900
tttgttacag actagcttcc ttctacgaag cagcaattcc cgaaatggag tctgcaatta    960
agaagaggag gcttgaagat agcaagcttc ttggtgacct gtggcagagg ctctcccatt   1020
ccaggaagaa gctaatggag attttccaca tcatcctgaa ccagatctgc ctccttccca   1080
tcctagaaag cagctgtgac aacattcagg gcttcatcga agagttcctt cagatcttca   1140
gctccttgct gcaggagaag aggttcctcc gggactatga tgcactcttc cccgtggccg   1200
aagacatcag cttgctgcag caggcctcat cagtcttgga cgagacgcgg actgcctaca   1260
tcctccaggc agtcgagagt gcatgggaag gggtggacag acggaaagcc acagatgcta   1320
aagacccatc ggtgattgag gagcctaatg gggagcctaa cggggtcacg gtgacagcag   1380
aggcagtcag tcaagcatca tcacatccgg agaactcgga ggaagaggag tgcatgggag   1440
cagccgcggc tgtgggccct gccatgtgtg gggtggaact ggactctctc atctcccaag   1500
tgaaggacct gctgccagac cttggtgagg gcttcatcct ggcctgcctg gagtactacc   1560
actacgaccc agagcaggtg atcaacaata tcctggagga gcggctggcc cccaccctca   1620
gccagctgga ccgcaaccta gacagagaaa tgaaaccaga ccctacaccc ctgctgacgt   1680
ctcgccacaa cgtcttccag aatgacgagt ttgatgtgtt cagcagggac tcagtagacc   1740
tgagccgggt gcacaagggc aagagcacca ggaaggagga aaacacgcgg agtttgctga   1800
acgacaagcg tgcagtggcg gcacagcggc agcgctacga gcagtacagc gtggtggtgg   1860
aggaggtgcc actgcagcca ggcgagagcc tgccctacca cagtgtctac tacgaggatg   1920
agtacgatga cacatacgat ggcaaccagg tgggcgccaa tgatgcagac tctgatgacg   1980
agctcatcag ccgcaggcca ttcaccatcc ctcaggtgct gagaaccaaa gtgcctagag   2040
aagggcagga ggaggatgac gacgatgagg aagacgatgc tgacgaggag gctcccaagc   2100
ccgaccattt tgttcaggac cctgcagtgc tgagagagaa ggcagaagcc aggcgcatgg   2160
cctttctcgc caagaaaggg taccggcatg acagctcaac agcagtggcc ggcagccccc   2220
gaggccatgg gcagagccgc gagacaaccc aggaacgcag gaagaaggaa gccaacaagg   2280
cgacaagagc caaccacaac cggagaacca tggccgaccg caagaggagc aaaggcatga   2340
tcccatcctg agacctggtg cagggccagt ggggaggcag cggcaccaga ctcaccaggc   2400
cgcgctccca tcgcctgggg cctcctcact aggggcccca agttcaactc aacccctcaa   2460
cagcctcagc tttgcagccc ctgagaaggc cgcctctcat ctaccagcca gccatgagcg   2520
ccttcctgca gaacacacag tgccttatgc cacagccgaa gaatccgtgg ggccggcaag   2580
caggcacctt cccccagctg cgctagcggg aaagagatgg ggatggagtc ccaaggcaag   2640
cgccccaaac ctcgggccac aagacaccac ttccccttta ccctggacag caggaaacct   2700
gtatattcaa aaacacaaaa agtcctgcta ataaaatttt tgaccctttc aaaaaaaaaa   2760
aaaaaaaaaa aaaaaaaaaa aaaaaa                                        2786

<210> 1013
<211> 2038
<212> DNA
<213> Homo sapiens

<400> 1013
ttttaaagtg caaaaagctc tctgctgccc tagagagagg atctttggac aggccgttca     60
atgcaaagta aaagggggca gctgatgggg ctcaacaaag ggcggtggag cgggagacac    120
catgctcccc tccctccctc cctccacaca cacgcgcaga atacactcag ccacacacac    180
agaggcacgt gcacaccccc ttccatggct gcaggcagag ggctggtgac tggcttctaa    240
gcaggacccc ctgactgccc tgaaagttca gtgagccact ggggctagac acaggcctgg    300
gctcaggggg ctccgctaaa ccagaggcct ggaggagcct ggctgggagg caggttgggg    360
cttggcccag tcctctgccg cctccagctt gggggagata ggctgctccc tctgaggacg    420
tgcatcctgg gaaagccttc ttcaggcaga atgaagacac atggaaaagg gcagtcagtg    480
ggaggcaaaa gagagagggg gaacaaggag atggtgcctg tctcagaatc cacttgggta    540
gcaacgaaat gggtgtgtcc ctggggtaga cagttccagc tcctctgaag agcttcaacc    600
ccaataagtg caataaggac ctcatagaga ctagcaagta agtcgggtag gctggggtgg    660
gaaacctaat tatgtgaaca agcacgagtg ctgggcagaa ccaagctcaa gggagaggaa    720
aggagggaga gcacagttaa ggacgtgagg tttgggagat ctcaacagca ccagtgtgat    780
cggcacgggt ctgggactcc tgggctgctg gcccctcctg cgcaagccgg gagagtgtga    840
tggaggagag acgcgcactg gacaccacaa gaacctggcc atggagacag ggccgttttc    900
ttccctggga gtttgctcag aaccaggcac tgctggggac catggatggg gaggaggggc    960
acagggccca gtgcagatga aggttgcaca aacaccccaa actgagagcc cggcctcctg   1020
gcaggcgagt aagcgagcag gcgcctcgac agcacagcct gtgctttccc ctcagatcaa   1080
tctgctactc ccttttcctt aggagggaga ggagcaggca gataagcctg gtgtccacca   1140
ccctctctgc cccacctgta gaggaagggc tcaagggaca ggagagcaga gagggagtgt   1200
gacgctggcc tcagagcccg tgcagggtcg aggagaggct ctcctcggtg gggagtcagg   1260
ggaagatcgg tttcctgttg aatctgggct gggtgtgtct tagctgatct tctgtatcag   1320
cttctcgtca gacaggcagt agaggctgtt gatggacaag tctgagatga agtgctcgca   1380
ggcttttcga gtgatctgct tgcatcctcg aaggtcgatc aaggtgacgt tggcaatgcg   1440
ccgtaggtag atcagggtct ggtctgtcaa tttattgcaa cctgccatat tgagctctgt   1500
gagagagtag cgagtggaag acccgacagc agtgagtaga ttggaggact gatctgtaag   1560
gtggctgcag tgactgaggt cgagtcgaga caggaggggc atgtggcgaa ttatgaggcg   1620
aagcgtggca tctgtgatgt caaggcctgc cagccggaag tcggtcatgt tccggagctt   1680
gctgcgattg tcctgacctg gtttatcagc cggtggagta agcaagtccc gaatttgagg   1740
gtccttgatt cctactgccc accgaagatc aagggtcctg agaagggggc agctggaggt   1800
gctgagggca gagactgcag accaggagca gcctgctagg aggaggtctt tcagtcctgg   1860
cagcctattg acgagccatg tcagttgctt tttagagatg ttggtccaac tgaggtcaag   1920
gctgactggc tgcctcttga tgatgccact gagggcctgg ggcacaatgg ccttacacct   1980
acwcaagtca atttttgtcc aaagtctctt gtcgcagcac cwktkctcgt gccgaatt     2038

<210> 1014
<211> 449
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (120)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (121)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (430)
<223> n equals a,t,g, or c

<400> 1014
ggcacgagcg cgggcggcgg gacggacgag gccggggccc cgggtggcac ccgcaggcgg     60
gcaggcgggc gccatggagc tgctctcggc gctgagcctg ggcgaactgg cgctcagctn    120
ntcgcgggtg ccgctcttcc ccgtcttsga cctcagttac ttcatcgtct ccatcctcta    180
cctcaagtat gagccaggag cagtcgaact gtcccggcgc caccccatcg cgtcctggct    240
gtgcgccatg ctgcattgct tcgggagcta catcctggct gatctgctcc ttggggagcc    300
actgatcgat tacttcagca acaactccag catcctgctk gcctcagctg tctggtactt    360
gattttcttc tgccccctgg acctcttcta caagtgtgtc tgcttccctg cctgtgaaac    420
tcatcttccn tggccatgaa agaagtggt                                      449

<210> 1015
<211> 695
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (677)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (687)
<223> n equals a,t,g, or c

<400> 1015
ntgtgatccc cgggttaaga attcscacat ggcggcggtg gtagctgcta cggcgctgaa     60
gggccggggg gcgagaaatg cccgcgtcct ccgggggatt ctcgcaggag ccacagctaa    120
caaggcttct cataacagga cccgggccct gcaaagccac agctccccag agggcaagga    180
ggaacctgaa cccctatccc cggagctgga atacattccc agaaagaggg gcaagaaccc    240
catgaaagct gtgggactgg cctgggccat cggcttccct tgtggtatcc tcctcttcat    300
cctcaccaag cgggaagtgg acaaggaccg tgtgaagcag atgaaggctc ggcagaacat    360
gcggttgtcc aacacgggcg agtatgagag ccagaggttc agggcttcct cccagagtgc    420
cccgtcccct gatgttgggt ctggggtgca gacctgagga gcgctgcgac cctcctaggc    480
tattgactgt taagtcctca ggtttggccc agattccagt tcgtgcctct gaggtccacc    540
agagggcgca tgaagcccag gctgttgcca aaccctaccc tgccccacac caaggagcca    600
gccaaaggca aataaagtta ttgagtgttt agtagaaagg aaaaaaaaaa aaaaytccaa    660
gggggggccc cggtaancca atttggnccc tataa                               695

<210> 1016
<211> 581
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (347)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (550)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (565)
<223> n equals a,t,g, or c

<400> 1016
ccatctactc tcctttttct cagtcctgat gtggacctag ggcaatgttw ctcaaacttt     60
gctgcatgtt gggatcactt aggaaatctt taaaaaatac tgatgcccgt ctcctacctt    120
ctgatttaat tagggtttga attggacttt gggattttgt ttttttaagt ccctagatgg    180
tttttaatgg gcaacaagct tgtgaaccat gaacttaggg gactagagaa gtcaagactg    240
gagagactgt ccataataac agaaagatga tattttggtg gcaccggtgc tgtttgtccc    300
actcttggta caactgtagg gtatgtgcgg attcttggcc tccggcntcc cctatcctca    360
gcgggcccag cctcytctgc tctccagtct tgcaaggccc tcggtgcttt cctcttcctc    420
ctcggtgcag gctgtggctt gccgtggctg cagccttagg ttcamcattt tctgcagtga    480
kctggggctc tctttgtgcc tgstgtgttc tgggtaatac agttgtggtt aaaggaagct    540
cattttttcn ggtccaacct ctgtnttccc acaatccttc g                        581

<210> 1017
<211> 2153
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2134)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2135)
<223> n equals a,t,g, or c

<400> 1017
caggcctcag ggcctctggt ggctctggcc cagacagtat ttgcagttct tgtgctatgg     60
gtgggagtct tcttcctcaa gtttcggcag ctgtgctgtg nctggatggg ctgctcctcc    120
cagggctcaa gggctgtggt ccgctcaggg tctcatttcc ccaggccaag ttcaaggcag    180
cagccctttg tgaggcgctc ttggccctgg gctggaggga gaactttaag cttttttgct    240
cacagggacg tggtatgggc cctgggtgca ggtgcccaca ttctgctaat gagagctttg    300
tctgatcagt cctgggtcca tcagtttgtc catgtgtccg gctgccagcc cgtcccttgg    360
gatccttccc ctggggtgta gccttgttca ttagtatata ctcattcctt catgctttcc    420
tcagcagaac acttccactt ctgaggtgag cttttgcccc gtgcccttcc tccacaggtg    480
ttgccttttt ataaagacct gatagcagaa taaattggtg tttccctgtt gacccagcac    540
catttctgtg ggcctagaat atggccctca acccttagag tggggcagtg agggcttgag    600
gagtgaccct tcctttctca tggttttagt cattttggct gccagccctt aatggcacag    660
atctgctgct tctaacagat ggccaggagg tgacaccgat ttcagccatt gccaaggtta    720
gcaccctctc ctttgagcct agggccacac tgttcattgt cactttaggc aagtgcctgt    780
ttggctttaa aggtaagcct gccagctgtg agaagccttg gtaactgatg gactcatttc    840
ctggtcctta aagatgcagc ctcttaaggg ctccttgatg gatgccatct ctcctagccc    900
ccagccctgg tgccactggt gggcaggttc ccattctttg gggctgggag ggacagcttg    960
cctgtttctg gtcacaaatt acagtcttct ctcctgtacc attctgtggc ttcagcatgg   1020
gggcagtagc cyttcattag tgtagatagt cattccctgg tagggtggag ggtaagacat   1080
agggtctgga actgtttggg accttttggg gatgtcctgt gcctcccaga ttcctmgatt   1140
ctgggaggag aggctgccgc attctgctgc tcctcacagc gagcaaagct gcacccactt   1200
acattcagta ttttcctggc actacaaaga gtgggaaggc ctgggatttg ctgctgctcc   1260
cttagagcag ggcccctctt ttcagcactt tggacacctg gagacccagc cctgttattt   1320
aatggtagtg ggcaagtgtg tgtgcatact gtctgccact gctttctccc tgccccatgc   1380
cagagagccc tgtccctgcc aggcccagcc ttcttagccc caacttggga acaaagtgca   1440
acatgggatc atgggttggg gtgctcaggt gagccctctc tatagtgctt ccctgggcca   1500
agctgacacc agcccctgag ggtggggtgg gacgggtggt gcttaaaaga ggaaggggac   1560
cagtgtagca acttgccagg gaccccaccc ctccctctct gggcctgtgc agtgagcatg   1620
gggattccca tcaaggggcc tggcacctgt gctagttacg tagccgctgc tcacgcgctc   1680
actcctgacc acatgcacgt tccctagatg cagactgctt tgaactttaa agctgtacaa   1740
tttggttatg tttgtgctga cttaaaatat attttaatga ggaaaaaata atggagaacc   1800
ctgggaagga cctggttctt ttgcttctcg gggaactgta agccctcgcg ttctgggaat   1860
cgctctctgc tgctctttcc tggaagctaa gcctgtctcc accgcccgag gcctgcgccg   1920
gtgctcccgc cgcagttgcg tttgctttgg accttgcgtg cgggggaggg ggtgctcggt   1980
ccgagcccgc tcctttctgt acacctagcg ctgcccgccc cgcttgtgtc tgaggtcgtg   2040
tatgtcaaaa ataaagccgc tagaaacgga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2100
aaactcgagg gggggcccgt acccaattaa cccnntatga tctataaagc gtc          2153

<210> 1018
<211> 855
<212> DNA
<213> Homo sapiens

<400> 1018
cttccccaac aaggagacga tgaatattca tttcaggggc aaaacaaaat cctttccaga     60
agagaaggat ggtgcttcat cctgtttagg aaagtctttg ggttcggagg attccagaaa    120
catgaaggag aagttggagg acatggagag tgtcctcaag gacctgacag aggagaagag    180
aaaagatgtg ctaaactccc tcgctaagtg cctcggcaag gaggatattc ggcaggatct    240
agagcaaaga gtatctgagg tcctgatttc cggggagcta cacatggagg acccagacaa    300
gcctctccta agcagccttt ttaatgctgc tggggtcttg gtagaagcgc gtgcaaaagc    360
cattctggac ttcctggatg ccctgctaga gctgtctgaa gagcagcagt ttgtggctga    420
ggccctggag aaggggaccc ttcctctgtt gaaggaccag gtgaaatctg tcatggagca    480
gaactgggat gagctggcca gcagtcctcc tgacatggac tatgaccctg aggcacgaat    540
tctctgtgcg ctgtatgttg ttgtctctat cctgctggag ctggctgagg ggcctacctc    600
tgtctcttcc taactacaaa agccctttct ccccacaagc ctctgggttt tccctttacc    660
agtctgtcct cactgccatc gccactacca tcctgtcacc agtgggacct ctttaaaaca    720
agcagccaac cattctttga tgtatcccat tcgctccatg ttaacatcca aaaccagcct    780
ggatttcata catggacttc tgattaaaag tggcaggttg tgcatgttaa aaaaaaaaaa    840
aaaaaaaaaa aaaaa                                                     855

<210> 1019
<211> 1207
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1195)
<223> n equals a,t,g, or c

<400> 1019
tcgacccacg cgtccggttg aattccttga cctgcaaaca catatttatt agcctgactc     60
aaacaatgaa gctattaaaa cttcggagga acattgtaaa actctctttg tatcggcatt    120
tcaccaacac gcttattttg gcagtggcag catccattgt gtttatcatc tggacaacca    180
tgaagttcag aatagtgaca tgtcagtcgg actggcggga gctgtgggta gacgatgcca    240
tctggcgctt gctgttctcc atgatcctct ttgtcatcat ggttctctgg cgaccatctg    300
caaacaacca gaggtttgcc ttttcaccat tgtctgagga agaggaggag gatgaacaaa    360
aggagcctat gctgaaagaa agctttgaag gaatgaaaat gagaagtacc aaacaagaac    420
ccaatggaaa tagtaaagtt aacaaagcac aggaagatga tttgaagtgg gtagaagaga    480
atgttccttc ttctgtgaca gatgtagcac ttccagccct tctggattca gatgaggaac    540
gaatgatcac acactttgaa aggtccaaaa tggagtaagg aatgggaaga tttgcagtta    600
aagatggcta ccatcaggga agagatcagc atctgtgtca gtcttctgta cggctccatg    660
ggattaaagg aagcaatgac atcctgatct gttccttgat ctttgggcat tggagttggc    720
gagaggtgtc agaacaaaga gaacatctta ctgaaaacaa gttcataaga tgagaaaaat    780
ctacgagctt cttatttaca acactgctgc cccctttcct cccagactct gacatggatg    840
ttcatgcaac ttaagtgtgt tgttcctgaa ctttctgtaa tgtttcattt tttaaatctg    900
acaaactaaa aagtttaacg tcttctaaaa gattgtcatc aacaccataa tatgtaatct    960
ccaggagcaa ctgcctgtaa tttttattta tttagggagt tacataggtg atgggggaaa   1020
ttgttaacta cctttcattt tcctgggaag tcaaggttac atcttgcaga ggttgttttg   1080
agaaaaaagg gcccttctga gttaaggagc catagttcta tcaatgatca aaagaaaaaa   1140
aaaaaaastc gaycggcacg agggggggcc cggtacccaa ttcgccctat gggantcgaa   1200
tgagacc                                                             1207

<210> 1020
<211> 894
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (751)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (887)
<223> n equals a,t,g, or c

<400> 1020
gaaattttac agtatctctg cctgaagatg aattaattca ggttacagtc acggcagtcg     60
caatcacttt tgacaaaaat caggctttac aaaccacaaa aacccctgtt gaaaagtcat    120
tgcaaagagc ctcaacagat aatgaagaac ttttacaatt tccactggaa ctgtgttcag    180
attcacttcc ttctcatcct tttccaccag ctaaagccat gacagttgaa aaagcaagtc    240
cagtgggtga tggaaatttc cggaatcgtt ctgctccacc ttgtgcaaat tccacagttg    300
gggttgttaa gatgacacct ctttctttta ttcctggagc aaaaataact aagtatcttg    360
ggataattaa catgtttttt attcgagaga ctacttctct tcgggaggaa ggaggagtca    420
gtggttttct ccatgctttt attgctgaag tgtttgcaat ggtgagagct catgttgctg    480
cattaggagg gaatgctgtt gtctcctaca taatgaagca gtgtgtcttc atggagaatc    540
caaataaaaa ccaggcacag tgtcttataa atgtaagtgg tgaygcagtg gtttttgttc    600
gtgaatctga cttagaagtg gtgtcatctc agcaacctac taccaactgc cagtcatcat    660
gtactgaagg cgaagttaca acctgaggaa aattaggaaa aaagagctca actaaatgaa    720
attcatcaat ctctggtatt ttggcattaa ntatcttctt agacttaaaa ttgacttgag    780
ataaataagg aagaattgag tagattggat ttgcctggag cttttggagg catgagaatt    840
ttctaacttg acatttggtt gcctggtcta aacaggccct ggggggnctt gacc          894

<210> 1021
<211> 625
<212> DNA
<213> Homo sapiens

<400> 1021
aggtccggga ctgggcgctg cggcctcgtc cgcgcgccgg ggcgggggcc tagctcgaca     60
gcttcccggc ggctgcgcga tggacagccc cgaggtgacc ttcactctcg cctatctggt    120
gttcgccgtg tgcttcgtgt tcacgcccaa cgagttccac gcggcggggc tcacggtgca    180
gaacctgctg tcgggctggc tgggcagcga ggacgccgcc ttcgtgccct tccacttgcg    240
ccgcacggcc gccacgctgt tgtgccactc gctgctgccg ctcggctact atgtgggcat    300
gtgccttgcg gcttcagaaa agcggctcca cgccctcagc caggcccctg aggcctggcg    360
gctcttcctg ctgctggccg tgaccctccc ctccatcgcc tgcatcctga tctactactg    420
gtcccgtgac cggtgggcct gccacccact ggcgcgcacc ctggccctct acgccctccc    480
acagtctggc tggcaggctg ttgcctcctc tgtcaacact gagttccggc ggattgacaa    540
tttgccaccg gtgcaccagg tgcccgtgtg aatgtgaaca gacactgggt gatgaaagtt    600
aaccaactta ccgagtggca agtgg                                          625

<210> 1022
<211> 1902
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (28)
<223> n equals a,t,g, or c

<400> 1022
tagcgcctgg gtcgctgggg tgtctctngt actctgggga ctgggtgcct cgctgggctt     60
cccgctgacc atttctgccg ccagcatcga gatagcacgg gttgcgattt caccgttagc    120
gtgacgctgc gggccccatc cctggctgat aaacgccggt ttggtactac cgatttcacg    180
agccaatttg atgattttgt ctgccggaac accagtgatt tgcgaggccc attccggcgt    240
tttagccacg ccatctggcc cttcacccag aatataagct ttatagtggc catttttcgg    300
cgcactggct ggcagggttt tctcatcgta gccaacgcaa tatttatcga ggaatgcctg    360
atccaccagg ttttcagtga tcatgacgta cgccagaccg ttaaccagtg cggcatctgt    420
tcccggacga atagggatcc actcatcttc gcgcccggca ccggtgtcgg tatagcgcgg    480
atcgatgatg atcatgcggg cattagattt ctggcgtgcc tgttcaagat agtaagtcac    540
cccaccgcca ctcattcgcg tttcgccagg gttattacca aacagcacta ccagcttact    600
gttttcgata tccgacgggg ctgttgccat ctgcccagcc gccgtagtat agttcaaacc    660
ttccgcaatt tgcgcggagg agtagtcgcc gtaatggttc agatagccgc cgcagcagtt    720
catcagccgc gcgaccaggg tatttcccgg cggccaggag cgggtcatgg tgccgcccag    780
cgtaccggtg ccatagttca gatagataga ctcgttgccg tactctttga tcaggcgctg    840
catattggtc gcgatgatgt cgtaggcttc ttcccagcta atgcgctcga atttgccttc    900
accgcgcgcc ccgactcgtt tcatcggata tttcaggcgg tccggattgt agacacggcg    960
acgcatggaa cgcccacgca ggcaggcgcg aacctggtgc aggccgtcgt aattgtcatc   1020
gccggtattg tccgtttcga catatttgat ttcaccgtcc acgacgtgca tacgtagcgg   1080
gcagcgacta ccacagttaa ctgtacaggc gctccagata accttttcgt ctgattttgt   1140
tggaatggcg ctatcgacag cgtgcgcaat ccgactaaaa ggtaatgtta atgcgctgct   1200
ggccattgcc aggccgccga tcgctgtcgt ttttaccaaa ccacggcgac tcacctcagc   1260
agccaatacc gcatcaggga ttttcgtttt cataatggct cactcaagct tgctcacgat   1320
tgattccagt aacaaaccgt attgtgtaat tatttctata gcagttcgct atataggctt   1380
gtatacatcg aataatttga aaatcaaaga gataggtaga ttttcactcg aaagtagtat   1440
tacgtgtaag tgaggagtaa ttattgttcg gtatcaaagg gagacaaaaa aagcgcccgc   1500
aggcgctttt tagattcaga aaaattgggt attagccaat atattccagt ccgttcatat   1560
acggacgcag aacttctggt acttcaatac gaccatcagc ctgctgatag ttttccatta   1620
ctgcaaccag cgtacgacca acagccagac cagaaccgtt cagggtatga accagacggg   1680
ttttcttgtc cgacttgctg cggcaacgtg cctgcatacg acgtgcctgg aaatcccaaa   1740
cgttggagca ggaagagatc tcacggtagg tgttctgtgc cgggatccat acttccaggt   1800
cgtaagtttt gcaagcgcca aagcccatgt cgccagtgca aaggatgatt ttacggtacg   1860
gcaggcccag caactgcagg actttttctg catgaccagt ca                      1902

<210> 1023
<211> 1617
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (92)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1539)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1563)
<223> n equals a,t,g, or c

<400> 1023
gcccaaggag ctcagcttcg cccgcatcaa ggccgtkgag tgcgtggaga gcaccgggcg     60
ccacatctac ttcacgctgg tgaccgaagg gngcggcgag atcgacttcc gctgccccct    120
ggaagatccc ggctggaacg cccagatcac cctaggcctg gtcaagttca agaaccagca    180
ggccatccag acagtgcggg cccggcagag cctcgggacc gggaccctcg tgtcctaaac    240
caccgggcgc accatctttc cttcatgcta cccaccacct cagtgctgag gtcaaggcag    300
cttcgttgtt ccctctggct tgtgggggca cggctgtgct ccatgtggca aggtggaagg    360
catggacgtg tggaggaggc gctggagctg aaggaatgga cgagccctgg gaggagggca    420
gaaggctacg cagggctgag gatgaagatg cagcccctgg atggtcccag actctcagga    480
catgcccagc tcaggggctt cgagccacag gcctggcctc atatggcatg agggggagct    540
ggcataggag ccccctccct gctgtggtcc tgccctctgt cctgcagact gctcttagcc    600
ccctggcttt gtgccaggcc tggargargg cagtccccca tggggtgccg agccaacgcc    660
tcargaatca rgaggcmagc ytggtaccaa aaggrgtacc cagggcctgg wacccaggcc    720
caytccagaa tggcctctgg actcaccttg agaaggctac gcagggctga ggatgaagat    780
gcagcccctg gatggtccca gactctcagg acatgcccag ctcaggggct tcgagccaca    840
ggcctggcct catatggcat gagggggagc tggcatagga gccccctccc tgctgtggtc    900
ctgccctctg tcctgcagac tgctcttagc cccctggctt tgtgccaggc ctggaggagg    960
gcagtccccc atggggtgcc gagccaacgc ctcaggaatc aggaggccag cctggtacca   1020
aaaggagtac ccagggcctg gtacccaggc ccactccaga atggcctctg gactcacctt   1080
gagaaggggg agctgctggg cctaaagccc actcctgggg gtctcctgct gcttaggtcc   1140
ttttgggacc cccacccatc caggcccttt ctttgcacac ttcttccccc acctctaygc   1200
atcttccccc cactgcggtg ttcggcctga aggtggtggg ggtgaggggg ggtttggcca   1260
ttagcatttc atgtctttcc ccaaatgaag atgccctgca aagggcagta accacacagt   1320
ttgctgagtg aaattctttg cccacaaaga cccagggctt ggagcatctc tytctttatc   1380
cttaatctcc caatttgcaa cccattctga agtctccagc ctggataggc agagacacta   1440
aaaccccagt agacagggcc ttggtggtcc taggaaggag ggcccataga ttctggaccg   1500
agggatgtca agctggtcag ttcagtccct atgaatgtnt cttctacagg aggctaccct   1560
gcncctgcta ccctggggag aagcctcagc tttctggggc agagtttgtc tccctgt      1617

<210> 1024
<211> 1496
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (525)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (616)
<223> n equals a,t,g, or c

<400> 1024
gccggaggtc tccgggtggt atcgcccttt cctctttgcc agcccgctgg cgagccgagc     60
crgggcaaga tgaggtcgtc ctgtgtcctg ctcaccgccc tggtggcgct ggccgcctat    120
tacgtctaca tcccgctgcc tggctccgtg tccgacccct ggaagctgat gctgctggac    180
gccactttcc ggggtgcaca gcaagtgagt aacctgatcc actacctggg actgagccat    240
cacctgctgg cactgaattt tatcattgtt tcttttggca aaaaaagcgc gtggtcttct    300
gcccaagtga aggtgaccga cacagacttt gatggtgtgg aagtcagagt gtttgaaggc    360
cctccgaagc ccgaagagcc actgaaacgc agcgtcgttt atatccacgg aggaggctgg    420
gccttggcaa gtgcaaaaat caggtaktat gatgagctgt gtacagcaat ggctgaggaa    480
ttgaatgctg tcattgtttc cattgaatac aggctagttc caaangttta ttttcctgag    540
caaattcatg atgttgtacg ggccacaaag tatttcctga agccagaagt cttacagaag    600
tatatggttg atccangcag aatttgcatt tctggtgaca gtgctggtgg aaatctggct    660
gctgcccttg gacaacagtt tactcaagat gccarcctaa aaaataagct caaactacaa    720
gctttaattt atccagttct tcaagcttta gattttaaca caccatctta tcagcaaaat    780
gtgaacaccc caatcctgcc ccgctatgtc atggtgaagt attgggtgga ctacttcaaa    840
ggcaactatg actttgtgca ggcaatgatc gttaacaatc acacttcact tgatgtggaa    900
gaggctgctg ctgtcagggc ccgtctaaac tggacatccc tcttgcctgc atccttcaca    960
aagaactaca agcctgttgt acagaccaca ggcaatgcag gattgtccag gagcttcctc   1020
agttgctgga tgcccgctcc gccccactca ttgcagacca ggcagtgctg cagctcctcc   1080
caaagaccta cattctgacg tgtgagcatg atgtcctcag agacgatggc atcatgtatg   1140
ccaagcgttt ggagagtgcc ggtgtggagg tgaccctgga tcactttgag gatggctttc   1200
acggatgtat gattttcact agctggccca ccamcttctc agtgggaatc cggactagga   1260
atagttacat caagtggcta gatcaaaacc tgtaaaggag caaaacttcc agmagcctcg   1320
agcccctctt gacctcctac acctgctttg gaaagacatg cactttttag tcgactaatt   1380
cttcctccca ttcccctcta cttgcgagtt atggaatttc tattccataa ctgaagtctt   1440
tatgataacc taatttttaa aaatgaattt gactaactta agtgcaaaac atgtaa       1496

<210> 1025
<211> 474
<212> DNA
<213> Homo sapiens

<400> 1025
aattccgcac gacgcggcca cagcccacag caggaaggcc tgcggaattc scgcatcgtc     60
agccagaagg acgacgtcac gtctgtatta tgtgcctacg cgccatcatg aactaccagt    120
ctggcttcag ccttgtcatg aaccacccag cctgtgtcaa tgagattgct ctgagcctca    180
acaacaagaa ccccagaacc aaggctctgg tgctggagct gctggcggcc gtgtgcttgg    240
tgcggggagg acatgacatc atccttgcag cctttgacaa cttcaaggag gtgtgtgggg    300
agcagcaccg ctttgaaaag ctgatggaat atttccggaa tgaggacagc aacatcgact    360
tcatggtggc ctgcatgcag ttcatcaaca ttgtggtaca ttcggtggak aacatgaact    420
tycgtgtctt ctgcattatg arttcaccca yttgggcytg gacctgtact tgga          474

<210> 1026
<211> 776
<212> DNA
<213> Homo sapiens

<400> 1026
gcccacgcgt ccgcccacgc gtccgcggac gcgtgggggg tgacattgag ctcaccagcg     60
ccaccgtccc cggcgaagtt ctgcgctggt cggcggagta gcaagtggcc atggggagcc    120
tcagcggtct gcgcctggca gcaggaagct gttttaggtt atgtgaaaga gatgtttcct    180
catctctaag gcttaccaga agctctgatt tgaagagaat aaatggattt tgcacaaaac    240
cacaggaaag tcccggagct ccatcccgca cttacaacag agtgccttta cacaaaccta    300
cggattggca gaaaaagatc ctcatatggt caggtcgctt caaaaaggaa gatgaaatcc    360
cagagactgt ctcgttggag atgcttgatg ctgcaaagaa caagatgcga gtgaagatca    420
gctatctaat gattgccctg acggtggtag gatgcatctt catggttatt gagggcaaga    480
aggctgccca aagacacgag actttaacaa gcttgaactt agaaaagaaa gctcgtctga    540
aagaggaagc agctatgaag gccaaaacag agtagcagag gtatccgtgt tggctggatt    600
ttgaaaatcc aggaattatg ttataacgtg cctgtattaa aaaggatgtg gtatgaggat    660
ccatttcata aagtatgatt tgcccaaacc tgtaccattt ccgtatttct gctgtagaag    720
tagaaataaa ttttcttaaa taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa        776

<210> 1027
<211> 724
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (629)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (705)
<223> n equals a,t,g, or c

<400> 1027
gtggttgcgg cggaggacgc aaccgagcgg gcctgcggcm tcaccatgga cccagaatgc     60
gcccagctgc tcccggctct ctgtgctgtt ctggtagatc ccaggcagcc ggtggcagat    120
gacacctgtt tggagaagct cctggactgg tttaaaacgg tcactgaagg agagtccagt    180
gtcgtgctgc tgcaggagca cccctgcctg gtggagctgc tgtcccatgt gctgaaagtc    240
caggacctga gttctggggt cctctccttc tcactgcgcc tggcaggaac cttcgcagcc    300
caggaaaact gcttccagta tcttcagcag ggggagttac taccagggct ctttggggag    360
ccaggacccc tcggccgagc aacctgggcc gtccccaccg tgcgcagcgg ctggatccag    420
ggcctgcgct ccctggcaca gcaccccagc gccctgckyt tcctggccga ccatggtgcg    480
gtcgacacca tcttctccct gcagggggac tccagcctgt ttgtggcctc ggcggccagt    540
cagctcctgg tgcacgtcct ggctttgtcc atgcgargtg garccgaggg gcagccctgc    600
ctgccggggg gttgactggc ccgcgtgtnc ccaaaaaatc atggatcacg tttgaaaaat    660
ccttgtgctc cgcgggcacc cccaaggtca ctccagccct gaacntcctg aacacaactt    720
ccgg                                                                 724

<210> 1028
<211> 2231
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2228)
<223> n equals a,t,g, or c

<400> 1028
ggcacagccg tgctccgggt aagatggcag cggacggaca gtgctcgctc cccgcttcat     60
ggcggccggt gaccctcacc cacgtcgaat atcctgcagg tgatctctcy ggccacctcc    120
ttgcctacct gagcctcagc cctgtatttg tcatcgtcgg tttcgtgacc ctcatcatat    180
ttaagcggga gctgcacacg atctccttcc ttgggggcct ggcactgaac gagggggtca    240
actggctgat caaaaacgtc atccaggagc cacggccctg tggaggcccc cacacagcag    300
tgggcaccaa gtacgggatg ccctccagcc attcccagtt tatgtggttc ttctccgtct    360
attccttcct tttcctgtat ttaagaatgc accaaacaaa caacgccagg ttcctggact    420
tgctgtggag gcacgtgctc tccctgggac tcctcgctgk ggccttccta gtctyctaca    480
gcagggtcta cctgctgtac cacacctgga gccaggtgct ctatggaggc atcgctggag    540
gcctcatggc catcgcctgg ttcatcttca cccaggaggt cctcaccccg ctgttcccca    600
ggatagcagc ctggcctgtc tccgagttct tcctaatccg agacacaagc ctcattccca    660
acgtactctg gtttgagtac acggtaaccc gggcagaagc caggmacaga caacgcaagc    720
tggggacgaa actgcagtga ccagtgggtg tggctgggtc cagcctccag atctggcccg    780
cacgatgcct tgcaggatgg acaggatgac agacagggac gaagcagaga cctctacaga    840
cccaagtcac caagtggagc cttttttttt cttattttaa ttttaatgaa caaggtggac    900
caaagggctg aaccagcccc tcaaccagga ccctgggggg cctgctgcct gggggccgtg    960
gccagagacc ctcgctgtgc tgctgccagc ccctggctgg ggcagaaagt gccctcggca   1020
tgggcacctg ggtgtggggt ggaggaggag ggctcgcgcc tctggtctcg gggccaggaa   1080
ttccaggtgg cgtgagaagt acacactatt tattttttgg ttttktcaga ggcaggcagg   1140
attttggagc tggaagaatc tgctctccgg tggctgccct gtgaacagag ggctcccggt   1200
cagcttccca ggcccttcgc cctatgccca gaggcagact gcctctccct gggccggggt   1260
ggcctgggtg ccaggaggag gggagcatac cccacaccct ccctgccacc gttgccgttc   1320
cagaacctcg gtcagtgttt ccctgtctgg gggcagggcc cagagcgagc acgcgtctgg   1380
cggctgctgt cgttgtgttc taccccgtac tgacccaaca ccacaagggc tttctctggt   1440
cccctgtccc taagacaata atcgctttct gacaaaggag cctgcacatt tgggtgagca   1500
gacccaagct gtttacagct ctttcttgtc ctgccatcca gtagcagtta gtcttcatcc   1560
ccacgtgaac aaaatgggaa ggagccgtga ggagaggagt gaggcaacag gcacccgaag   1620
tccctcgtcc ttccctctgt gtgctctgaa tatgtccttg tccttcctga cccatctctg   1680
accagctggg aacctgcttg gggtccccct caaacctgtg tctggggtgt gggctcacag   1740
atccctatca gcctggttcg tgggagggct cttcctaaag ggacccccat ctctaagtca   1800
ctctgaaagg gagttgtgga gaggagacgc ctccagactc tcagaagttt tgaggactga   1860
actgggtcac tcgggatctg tgttcgaatc ctccccaccc ctttctttgt ggagtttcct   1920
aacctgctgc tgaagcacaa tgttttggtg ctttcttttc tcatttgtta aaggcagtgt   1980
ccaaaagcca ttccagatgc caagaccagg ggcttatttc tagggaaggt aggtcggttt   2040
ccatgtttcc ctcccgttat ttttattttt tactttttgc ctgagacaag ccgagtatga   2100
ggtggtttga tttaagaaaa atcaatgaaa ttgtttacta ctgttttaaa ataaaaccgt   2160
aaactctgaa aaaaaaaaaa aaaaaaaaaa aaaaaactcg agggggggcc cggtacccaa   2220
tcgcatcnca t                                                        2231

<210> 1029
<211> 2033
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1539)
<223> n equals a,t,g, or c

<400> 1029
ggcacgaggt gagctggtgg tggggggaga gcccagtgct gggcagaagg gcgctgcttc     60
tctttgatga ctctttcctg catgctgcgt tccatgaagg ttcagcagag gatggcccac    120
gggtggtttt catggtggat ttgtggcatc caaacgtcgc agcggccgaa cgcaggctct    180
tgatttcatc tttgctccgg gacgatgaga gtatttccca tgctggagtc ggcgagaagg    240
gccgaggcgg ggcctgggca gactgtggtc cggtccagtc cctaccggtg ttgtttccat    300
gctcagaaac ctgcctcagc ggaaagctct tatttgggat tttatatcat gtcgggtccc    360
tctttccctt ggttattgta aatggaaact tttcggcttg tatttcctta gatttttttt    420
ttttccttcc aatcatttgc ttcagagact cctttctggc ctaacagcgc attcctttga    480
ttggtccttg agtgaccaga gacttagtgc ccttgtaagt ctgtcttctg ttgctacttg    540
tttttttcag tgctctgaaa tagagtaact aaatggttat ttgtctgaat ataataatgt    600
aaaacttctt gtggtcatct taaaaaaaaa aaaaaaaaac taaaaactgc aaaccagaga    660
gctagagaac ttggcctctg atgctggcac acwggggacc cttcagccac ctgacggcag    720
ggggacagtc tgcagccccc acacctgact ggcttcagta gccaggtgga ggggctgcca    780
gacacagtca gggtggcaca cagtgtccag gcccagggat actgtcacca tcgctcacct    840
cattctaaac cttgtcaggt ccctgatggc aaaagcattg ggccagtagg actggaggct    900
actctttaaa catggctttc ctgcaaagct gaagctggtg tcccccagca ccaagctgcg    960
gctcacacag atcagccacg gaacgtgtga tccgcttacc tcactgccta cagaagccct   1020
actgccaaac tgggcctgga aaattcccag ttttaggtgt tttgagtcca cagtgatgaa   1080
cgttaaggcc accaggttgg ctgataggag ctgtaggggg ataggaccgc gctcacccag   1140
cgacatttgg ggaaagcctt tctctggcaa aactggaata atagatctga ccaaagtttc   1200
tgttttgctt tggagttctg ttgcctatgt tttttttttt tttttttttt gtctgtacat   1260
aaatgttcaa acactagact tggagatagt ggaagagttg gccctgtgtc tttgtcatgg   1320
cacaaaggtg tgcactgcgt gacaatgacc caagccagtg tgtgctagtg aggagacaga   1380
gaagacctac atgcccagag gacccgtggc cgttgtgctg gttttctggt ctcctgtgaa   1440
gaacatgtgg atctcttccc gaagaaaagg tcccaggaga ccagtttgag gcactcactc   1500
tagaaatagc ctgtgttagc tgatgtgtga aagcgtasnc ggccagccac actagagatg   1560
ccttttctga ataatgtatt atgagcagtg tcagatttat aaagccgagg agtggtttgg   1620
aatatacagc tggtcgcagg tgcaggtcca gtgtttagat ccaaatggaa aacagcagct   1680
tctaagaggt acaactgttg gaagaaaaca cagttgaaat gcaccaggca ggtactagca   1740
agtgtgcaaa gagcacgtct acatttgagt aaaatgtcta cacagatatt tgtcagtgat   1800
gagaatgcag gaaaaggcag acatttcaaa catacctgaa gtctttttac tcattatctt   1860
gttaaagaat cactgaggtg catgatttct acacatcgtg actgctctgc tctgcgttta   1920
caaaaccaac agcccgcgca ggtacctagc tacctgcatt catgtgacat gtctggggaa   1980
cagaagataa ataaaggatc ttgctgaaaa ccaaaaaaaa aaaaaaamaa aaa          2033

<210> 1030
<211> 819
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (733)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (754)
<223> n equals a,t,g, or c

<400> 1030
ggcgcccgag tgcggtactg gcggcgggcg gcgggcagcc atggcggagg ccgcgtcgcc     60
gcacttgtcg ctgccctcgg ggctgctgga gctctgcgcg ctgctgggcg ccccccggga    120
cagtctccga agtctcgagc aggttgctta taaaaaggga gtcaaacatc tttctgctct    180
tcttgatcca gaggtcctgt ccattttcgt gcctcctttt atcagtaaag aggacagtca    240
aacggccggt gccaactgcg gcactctcgg taaaacccgg atgcgctcct tgagaaagaa    300
gagagagaag cccagaccag agcagtggaa gggsctcccg gggcccccca ragcgccara    360
gcctgaggat gtcgccgtcc cgggcggcgt ggacctcctc accctgccgc agctgtgctt    420
cccagggggt gtgtgcgtgg ccactgaacc taaggaggat tgcgtccact tcctggtgct    480
gaccgatgtc tgcgggaata ggacctatgg cgtggtggcc cagtactacc ggcccctgca    540
tgatgagtac tgtttctaca atrgcaaaac gcaccgggag tgtcctggct gcttcgtgcc    600
cttcgcggtg tgcgtggtct ccargtttcc ctattacaac tccctcaagg actgcctttc    660
ctgtttattg gctcttctga agccctgtaa agattttgaa gtggacagtc atataaaaga    720
tttcgctgcg aantgtcttt aatacccagc ccgncacctg gaccgctcca tttggtattt    780
aacatgaagt cgctccagat tgtgttacct gcccgagca                           819

<210> 1031
<211> 565
<212> DNA
<213> Homo sapiens

<400> 1031
gccaagggca aactcttcct gcaccgcgtg ggccgtgtgg ctcgggctgg ccgaagtggc     60
acagcctact ccttggtggc ccctgatgaa atcccctacc tgctggatct gcacctgttc    120
ctgggccgct ccctcacctc gcccgacccc tcaaggagcc ctcaggtgtg gccggtgtgg    180
atggcatgct gggtcgggtg ccacagagtg tggtgggcat cagcagacgt tcccgtgcac    240
cactgtgtgc ctggccctgt gctgggcact gggggcactc cctgcaggag ccatcatctg    300
tgaaaaggag cactgtatgg ccacagaagg gcagcagctg cgtcagccta agacagagac    360
atttgaacag ggccttgaag ggtgtgcagg agttcgccag caaagccagg caggccaaga    420
cttgagttgg caactcagct gctgctgctt ccatgtgttc tgggttcaga ggtcatggct    480
gcaccggtca gagccctgag tgcctcaggg tttggcaatg gaatttttaa tgtaataaat    540
ctttattgag cactgaaaaa aaaaa                                          565

<210> 1032
<211> 562
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (299)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (317)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (508)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (554)
<223> n equals a,t,g, or c

<400> 1032
gcggccgcca ctggagacac tccctcccgc ctcccgggtc tcctggcggc ggcggagtga     60
ggctgacagc ggggaacctg ggagacccct ccgccctccc cgcggtggca gcggccgatc    120
cccggctccg gcgcgaggga cggccgcgat gcctcggcct gaggttaccc ggcccggccc    180
ttcctcgctt ccctcgacta ttccactgcg tctccgcgcc ccgggtcatc ctgcgagtcc    240
ctctgacggg agggaagatg gctgcacgga gctggcagga cgagctggcc cagcaggcng    300
aggagggctc ggcgkcntgc gggaaatgct ctcggtcggc ctaggctttc tgcgcaccga    360
gctgggcctc gacctggggc tggagccgaa acggtacccc ggctgggtga tcctggtggg    420
cactggcgcg ctcgggctgc tgctgctgtt tctgctgggc tacggctggg cgcggcttgc    480
gcggcgcccg caaaaagcga ggagcccncc ccgcaagcgg gaggaggcgg cggccgtgcc    540
ggccgcggtc cccnacgacc tg                                             562

<210> 1033
<211> 2645
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (508)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (971)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2034)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2641)
<223> n equals a,t,g, or c

<400> 1033
gcaacgagct ccaatccctg ccctcggaac tgtgtggcct ctcttcctgc gggacctcaa     60
tgtccggagg aaccagctca gtacgctgcc cgaagagctg ggggacctcc ctctggtccg    120
cctggatttc tcctgtaacc gcgtctcccg aatcccagtc tccttctgcc gcctgaggca    180
cctgcaggtc attctgctgg acagcaaccc tctgcagagt ccacctgccc aggtctgcct    240
gaaggggaaa cttcacatct tcaagtattt gtccacagag gccgggcagc gtgggtcggc    300
cctgggggac ctggcccctt ctcggccccc gagtttcagt ccctgccctg cagaggatct    360
atttccggga catcggtacg atggtgggct ggactcaggc ttccacagcg ttgatagtgg    420
cagcaagagg tggtctggaa atgagtcaac agatgaattt tcagagctgt cattccggat    480
ctcagagctg gcccgggagc cccggggncc cagagaacgc aaggaggatg gctcagcgga    540
cggagaccct gtgcagattg acttcatcga cagccatgtc cccggggagg atgaagagcg    600
aggcactgtg gaggagcagc gaccacccga attaagccct ggggcagggg acagggagag    660
ggcaccaagc agcaggcggg aggagccggc aggggaggag cggcggcgcc cggacacctt    720
gcagctgtgg caggagcggg aacggcggca gcagcagcag agcggggcgt ggggggcccc    780
gaggaaggat agcctcttga agccagggct cagggctgtt gtgggagggg ccgccgccgt    840
gtccactcaa gccatgcaca acggctcgcc taagtccagt gcctcccaag caggggctgc    900
agcggggcag ggagccccgc ccctgcccct gcctcccaag agccccttcc catagctgga    960
ccagcgacag nacctgctcc acggccactt ggctccattc agagaccaaa cagcttcctc   1020
ttccgttcct cctctcagag tggctcaggc ccttcctcac cagactctgt cctgagacct   1080
cggcggtacc cccaggttcc agatgagaag gacttaatga ctcagctgcg ccaggtcctt   1140
gagtcccggc tgcagcggcc cctgcctgag gacctggccg aggctctggc cagtggggtc   1200
atcctgtgcc agctggccaa ccagctacgg scgcgctccg tgcccttcat ccatgtgccc   1260
tcccctgctg tgccaaaact cagtgccctc aaggctcgga agaatgtgga gagttttcta   1320
gaagcctgtc gaaaaatggg ggtgcctgag gctgacctgt gctcgccctc ggatctcctc   1380
cagggcactg cccgggggct gcggaccgcg ctggaggccg tgaagcgggt ggggggcaag   1440
gccctaccgc ccctctggcc cccctctggt ctgggcggct tcgtcgtctt ctacgtggtc   1500
ctcatgctgc tgctctatgt cacctacact cggctcctgg gttcctaggc cccaaaatcg   1560
gccctccctc acccctttcc cttcctctct atttataagg tccctgctcc acccgacccc   1620
acctgcggtg ccttcagccc caaccaaaga cactagtgca cccccttcac agacactgac   1680
ctcagaggcc ccactctggt gcccccagac cctgggcccc cagcctctgg cctccctcca   1740
gtagccccac gagtccccac ctctcagtgc tgacggtgcc ttcatgtccc cgccggccct   1800
gcccctgccc tctgtacccc gtgaggggtg gcaggagctg gagtctcccc cttcctcctg   1860
tgccctcccc ttcccccccc aacagctgct atgggggggc taaattatct ctattttgta   1920
gagaggatct atatttgtag gggttcgggg cccaggccgg gtccctatct ctgtgtataa   1980
actgtacaga ccgtggccgc cctgcctgtg tgtgtgtgtg tgcgcgcgcg cgsncgtctg   2040
ctccgcgtgt tggtggctgt ggccatggct ctgtgcccac cagcatctcc ctcctgagat   2100
gccggcctct catgctcccg gagcgtccgc caaccccccg tgtcacctmc cttstgttat   2160
cgctgacagc tttcttgcgt ctcatttgtc gccgagcccc gagcgcaggt gatgctcggg   2220
tctgcccccg accccctgcc acargccgga agccgcaggg ggcamcgtgg ggaarctaac   2280
ccggcccctt cccccargag tcactgtgcc agccccacca catcctggaa gaggaggggg   2340
ccccggraag gggcctcccc tacatcgctg ctgtcgtcca cgccctgctg gaccggcctt   2400
aggggtgaag gtgggggcac agggcccacc ccgcccggga ccccgggagc agaagacgcg   2460
cctgggctcc gcgctctcag agaagcacgt ggtgagggtg gcctgggcct gggcaccctt   2520
ggcctgccgg cctggctgcc tctggggtcg agggtctggg tggaaggacc gcgggtgtcg   2580
caggtgtcgt gtcagccgca ataaacagaa gccagaaraa aaaaaaaaaa aaaaaaaggg   2640
nggcc                                                               2645

<210> 1034
<211> 596
<212> DNA
<213> Homo sapiens

<400> 1034
tgataatata gcttataatt agcttatcaa ttaaatatgc atggctgtat ctaaagggct     60
tgaaaactgt ttttaaggtt tttcttttct atcttgattt tatatttagg aaamcccagg    120
taaactcaca aatagrggaa cattttttta agcaggaaaa tatgtaacaa tttttgggcc    180
aaatgcttaa gaagtgagaa ttttgaaatg gaaacaaaag ttggaatctg tcttagaagt    240
aatctactcc accccttctc tcccagcagt ttgagtgctc tatttaaagc tagaattttg    300
agcatgagaa cgccactgtg gacaacagag agattttctc tctctctcac ctcttctctt    360
tctctccttc tatctccccc tccaccacca tctctctcat cttcttccct ttgtccccac    420
cccattgctt ttttctttct gcttttcctg ttccctatcc ttacgcagga ttgttttact    480
gttagccagg ttaagtttaa gcttcttgag gactttagta ctgaaagaca atggctcact    540
tgtaagacct agttgaagag tacagattta gatttgttca gtgtgctgtg atctgt        596

<210> 1035
<211> 503
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (481)
<223> n equals a,t,g, or c

<400> 1035
ggcacgagag cgcctggagc cacacaggga tccggagcct gggggaaaag cggcgcggga     60
gccggcaccc accgctggag gggcggcgac ggcggccgta gcgacctcgg gaggcaagcg    120
gagccgccat ggccgagttc ccgtcgaaag ttagcacgcg gaccagcagt cctgcgcagg    180
gcgccgaagc ctcggtgtcg gcgctgcgcc cggacctggg cttcgtgcgc tcccgcctcg    240
gggcgctcat gctgctgcag ctggtgctgg ggctgctggt gtgggcgctg attgcggaca    300
ccccgtacca cctgtatccg gcctatggct gggtgatgtt cgtcgctgtc ttcctctggc    360
tggtgacaat cgtcctcttc aacctctacc tgtttcagct gcacatgaag ttgtacatgg    420
ttccctggcc actggtgtta atgatcttta acatcagcgg caccgttctc tacatcaccg    480
ncttcatcgg ctgctctgcg gca                                            503

<210> 1036
<211> 2520
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> n equals a,t,g, or c

<400> 1036
cgcatcccgc accaaagttt tccccgggga gcgcgtagag catgtaactt ttaacttcac     60
gttggagaat cagatccacc gaggcgggca gtacttcant gacaagttca ttgggctgcg    120
gctcaagtca gtgtcctttg aggattccct gtttgaagag tgttattttg aggatgtcac    180
atccagcaac acgtttttcc gcaactgcac attcatcaac actgtgttct ataacactga    240
cctgttcgag tacaagtttg tgaacagccg tctgataaac agtacattcc tgcacaacaa    300
ggagggctgc ccgctagacg tgacagggac gggcgaaggt gcctacatgg tatactttgt    360
gagcttcctg gggacactgg cagtgcttcc tgggaatatc gtgtctgccc tgctcatgga    420
caagatcggc aggctcagaa tgcttgctgg ctccagcgtg atgtcctgtg tctcctgctt    480
cttcctgtct tttgggaaca gtgagtcggc catgatcgct ctgctctgcc tttttggcgg    540
ggtcagcatt gcatcctgga atgcgctgga cgtgttgact gttgaactct acccctcaga    600
caagaggacc acagcttttg gcttcctgaa tgccctgtgt aagctggcag ctgtgctggg    660
gatcagcatc ttcacatcct tcgtgggaat caccaaggct gcacccatcc tctttgcctc    720
agctgccctt gcccttggca gctctctggc cctgaagctg cctgagaccc gggggcaggt    780
gctgcagtga aggggtctct agggctttgg gattggcagg cacactgtga gaccaacaac    840
tccttccttc ccctccctgc cctgccatcc tgacctccag agccctcact ccccactccc    900
cgtgtttggt gtcttagctg tgtgtgcgtg tgcgtgtgca tgtgtgtaaa ccccgtgggc    960
agggactaca gggaaggctc cttcatccca gttttgagat gaagctgtac tccccatttc   1020
ccactgccct tgactttgca caagagaagg ctgagcccca tccttctccc cctgttagag   1080
aggggccctt gcttccctgt tccaggggtt ccagaatagg cttcctgcct tccccatcat   1140
tccctctgcc taggccctgg tgaaaccaca ggtatgcaat tatgctaggg gctggggctc   1200
tggtgtagac catggaccaa aagaacttct tagagtctga agagtgggcc tcgggtgccc   1260
tctcacatct cctgttggat gctgggggag aagcaataaa cctcagccct ctggcctcca   1320
ctttcctctc aatttgggct gcaaatatga agcctgaatt ttatgaaatt agctttctga   1380
ttcttattta ttaatagatt aagttctgag gcagctccgc agactgtgtg tgaatgtgta   1440
tgtatactta catatgtgtg tgcatgtgcc atggggcggg gggtatcact atactgtcct   1500
caaatataag ccaagggtaa tttcagcgga tgcacacaca accctgcctc ccacagttcc   1560
tcccctaatc tggtttctgt gttgagcctg ggatggagga gccctaggcc agcctgggat   1620
aagagtccca cagtctaggg agatctgagg gcatccgaca aggcccatct ccttccctcc   1680
tcaagaagca gaggcctcct ctggagtgag aggctccacc cactacagca caggcgggaa   1740
tagcacagct gccctcccat gctccctacc tgtcccctca cagggagggg agcaggggag   1800
ggaaagaaac caggcatctg gtcaaaccag cagatcaaaa agcacaaaga gctggggcag   1860
aggcaggaag caggggccct cctggcagct cctctgagtg gggagaggtt gggcagtgag   1920
tgagggaccc ctaatgcagg gactagaagc ctcagtttcc ccattttacc cttccacaca   1980
atagcctctg taggttaggc tgccccatcc caccctactc tgtgtggctg ctttctttgg   2040
tgccctcccc tcaccccact gtagctgtga cgtgttgtag tttttagatg tttgtaaaat   2100
gtttaaaaaa atgttaaaag gaaaaaagtg aaaataacaa aaaagaaaat caaaattcac   2160
cttcgtcatg ctgcgtccag tgccccaacc ctgtggtcac tctccccatt ttgtaacact   2220
gtaccaggtg gtgactgttt aactctttgg tgtctgtgct caaaagactg ccttctccag   2280
tgcccagtgt atgagtgtgt gccctgtgcc cttgtccctc actccccaca tgctggacgt   2340
agccctcttc ctcgcacccc tgggagggac ccatccatct cccttgctct cctggggaac   2400
cctaaaccca actctgttga tgtgaaaaat gcagtgaaaa atattgacga aaaataaaac   2460
ggaaacaaat cctcaaaata caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaagg   2520

<210> 1037
<211> 1461
<212> DNA
<213> Homo sapiens

<400> 1037
ggcgcactga tcccgcctgg ggccggctga gtggcactta agcgggccat gccatgcaac     60
cttgggcgct gccaaccgtg ggcgagctct gggtgtgcgg gcggcctggc gcggcgctcc    120
gctgtgtcag cgtgttatga tgccgtcccg taccaacctg gctactggaa tccccagtag    180
taaagtgaaa tattcaaggc tctccagcac agacgatggc tacattgacc ttcagtttaa    240
gaaaacccct cctaagatcc cttataaggc catcgcactt gccactgtgc tgtttttgat    300
tggcgccttt ctcattatta taggctccct cctgctgtca ggctacatca gcaaaggggg    360
ggcagaccgg gccgttccag tgctgatcat tggcattctg gtgttcctac ccggatttta    420
ccacctgcgc atcgcttact atgcatccaa aggctaccgt ggttactcct atgatgacat    480
tccagacttt gatgactagc acccacccca tagctgagga ggagtcacag tggaactgtc    540
ccagctttaa gatatctagc agaaactata gctgaggact aaggaattct gcagcttgca    600
gatgtttaag aaaataatgg ccagattttt tgggtccttc ccaaagatgt taagtgaacc    660
tacagttagc taattaggac aagctctatt tttcatccct gggccctgac aagtttttcc    720
acaggaatat gtatcatgga agaatagagg ttattctgta atggaaaagt gttgcctgcc    780
accaccctct gtagagctga gcatttcttt taaatagtct tcattgccaa tttgttcttg    840
tagcaaatgg aacaatgtgg tatggctaat ttcttattat taagtarttt attttaaaaa    900
tatctgagta tattatcctg tacacttatc cctaccttca tgttccagtg gaagacctta    960
gtaaaatcaa agatcagtga gttcatctgt aatatttttt ttacttgctt tcttactgac   1020
agcaaccagg aattttttta tcctgcagag caagttttca aaatgtaaat acttcctctg   1080
tttaacagtc cttggaccat tctgatccag ttcaccagta ggttggacag catataattt   1140
gcatcatttt gtcccttgta aatcaagatg ttctgcagat tattccttta acggccggac   1200
ttttggctgt ttcctaatga aacatgtagt ggttattatt tagagtttat agccgtattg   1260
ctagcacctt gtagtatgtc atcattctgc tcatgattcc aaggatcagc ctggatgcct   1320
agaggactag atcaccttag tttgattcta ttttttagct tgcaaaaagt gacttatatt   1380
ccaaagaaat taaaatgttg aaatccaaat cctagaaata aaatgagtta acttcaaama   1440
aaaaaaaaaa aaaaaactcg a                                             1461

<210> 1038
<211> 1771
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1745)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1757)
<223> n equals a,t,g, or c

<400> 1038
gcagcactcg gttccgtgca actttcaagt gagttgcgaa ctccgccctg taggccggtg     60
ctggtggccc ggcgcgctgg aaccgcggcg acccgctcca gcgcgggacc agcagcaagg    120
gccgagcgcc aggttctccg cggcagaaag ggcgggtggg agctgtaact gccccggccg    180
cggggcgcgc ccgctcccaa gtcggcttcc tccccgccgg ggccgctttg cctcgggtct    240
ccccattctc caggtcccct gaactgcaca gtcggaggcc gtgggcggcg ggctctgcct    300
ccgccgaggg acagccggat cgcccctctg cttcccgcaa ctgccctgat caccccccgt    360
cccagccctt gagtgaacgt ccttctgagc ggcttcctgg ggtcctcccc acgtcccaaa    420
ggccggcaag atggtgtcct ggatgatctg tcgcctggtg gtgctggtgt ttgggatgct    480
gtgtccagct tatgcttcct ataaggctgt gaagaccaag aacattcgtg aatatgtgcg    540
gtggatgatg tactggattg tttttgcact cttcatggca gcagagatcg ttacagacat    600
ttttatctcc tggttccctt tctactatga gatcaagatg gccttcgtgc tgtggctgct    660
ctcaccctac accaagggcg ccagctgctt taccgcaagt ttgtccaccc gtccctgtcc    720
cgccatgaga aggagatcga cgcgtacatc gtgcaggcca aggagcgcag ctacgagacc    780
gtgctcagct tcgggaagcg gggcctcaac attgccgcct ccgctgctgt gcaggctgcc    840
accaagagtc agggggcgct ggccggcagg ctgcggagct tctccatgca ggacctgcgc    900
tccatctctg acgcacctgc ccctgcctac catgaccccc tctacctgga ggaccaggtg    960
tcccaccgga ggccacccat tgggtaccgg gccgggggcc tgcaggacag cgacaccgag   1020
gatgagtgtt ggtcagatac tgaggcagtc ccccgggcgc cagcccggcc ccgagagaag   1080
cccctaatcc gcagccagag cctgcgtgtg gtcaagagga agccaccggt gcgggagggc   1140
acctcgcgct ccctgaaggt tcggacgarg aaaaagactg tgccctcaga cgtggacagc   1200
tagggtctgc tgcatctgcc cccttcttac ctcgtgccct gcagggctcc agggctattt   1260
ggagggacct tgggctgcac atctggcctg cctgcaccag ctgcctgggc cccaccctcc   1320
tgactcctgc tgatggttaa gggccgggag cagatgctgc caaggccaca tgcagggatg   1380
cacccacaat gtaccaaagc aggctgggcc cagggttcta tttattgcct tgctctgccc   1440
tctcccttcc ccggttgtgg gacaagagcc ctccctgaac ccctgcaacc ctccctgaac   1500
ccctgcaaat gaaaccaaac gtccacctgg gtgtgttcat tccttcctgt ccttcaaagt   1560
acttgatagc ctttcataag gcctggcaca tgtgtcctgg ttgtgtgtgt gtgtgttggt   1620
gagtgaggtc aggtttgcga gtgttttgat aaataaatac ataaaggggc aaaaaaaaaa   1680
aaaaaaaaaa aaaaamaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1740
aaaanaaaaa aaaaaanaaa aaaaaaaagg g                                  1771

<210> 1039
<211> 1519
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (715)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (747)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1397)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1409)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1423)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1431)
<223> n equals a,t,g, or c

<400> 1039
tcgacccacg cgtccgctca gagaatgtcc agagctaagt ctgagcaaag ggccagcttt     60
tgcttttggg gctggggtac aggcagattc ctgttggaga gcatttattt tacttttcaa    120
gtgtgggctt tctggaaggt aatgggaaac tgcaaggtgt cttgcaagca ggtgtttggc    180
ttatggtgat gtggttccca gggtggcttt tgggcagggg cagggcgggg tcctccagga    240
gctgtctgtc ggtgctgagc tcagtctgct tccctaccac tcagcccamt gcttggatgg    300
ttccctctgt camtctcatc ttacamtgtc caggttttag cactgaaatc atatgtgtgg    360
gaagcctctc agtcccaggc caaccagaac agttggtcgc cccgtgtcta acatacctgt    420
ctaactgtct ccagggcatg gctcatcagc gtggctgtgg caccctctcc ctgccttctc    480
ttgtctcctt cactgtcaag tctgggaaag ggctcctggt gggtgtccga tgaggcacag    540
ctgggtgaca aagatggctc cagctctggt tggggcgtgc acctcatggt gacacctccc    600
tctgtgggac ctccgagggt caaggaagga ggcaccttcc atcctaggtt taggattcat    660
tgcacttaca caggattccc cgtggcagat cacctgtgtt ccagargctg tgtanttcaa    720
ggtgtgtgtg aggcagttgc atggtanggg ggcacctata actgggggta agtctgtaat    780
ggtgcaatag atgatgttag aacagtgggg gtccccctcc ctctcaggcc tcaaaagcac    840
aaccaccaga rctggtgggt ggcactgggc catggggaga cctgaccagc aaggctccct    900
ctttcctctg tccaggccac ccagcctgar atacagtgct ggtcactcta aggaatgctg    960
tggcccccaa gggacacccc ttgggtggct cctcccwggc ttctcactgc kggctggcar   1020
gcargctggt gggcgggcaa rcgtaatatt acccctaaga taaatgaaga agagtttcag   1080
cccttattgg attatagttt ttattgaact ttataaattc caattagcag acccctgggc   1140
aataagcgac acacagcccg tggctcgctt tatagcgtga ttatgaccct gtttatcctc   1200
ccctgaacga gaagtattaa tggaggaaac aaaggaaagg gactcaaaaa tacataaaaa   1260
cagatattgg tgacacagag ataaacagac aggagtcagg gagagaaaac aatctccggg   1320
caggcaaggg ggaacagaga atcagagatt ctaagaaccc atgtgctcag accaccgtga   1380
gcttggatgt ccttctnggc tcctcccang gcacaaaccc ctnagctcct naagctgctg   1440
gggctgaaga gacctccctc ccaagcctac tcaggatctt gctggggtgg atgtgattat   1500
aatgaaatca ggtgccacc                                                1519

<210> 1040
<211> 1448
<212> DNA
<213> Homo sapiens

<400> 1040
gtctatccat tttttggagt ctgaattcag tagaggaatt tcagacaatt atactctagc     60
ccttataact tatgcattgt catcagtggg gagtcctaaa gcgaaggaag ctttgaatat    120
gctgacttgg agagcagaac aagaaggtgg catgcaattc tgggtgtcat cagagtccaa    180
actttctgac tcctggcagc cacgctccct ggatattgaa gttgcagcct atgcactgct    240
ctcacacttc ttacaatttc agacttctga gggaatccca attatgaggt ggctaagcag    300
gcaaagaaat agcttgggtg gttttgcatc tactcaggat accactgtgg ctttaaaggc    360
tctgtctgaa tttgcagccc taatgaatac agaaaggaca aatatccaag tgaccgtgac    420
ggggcctagc tcaccaagtc ctgtaaagtt tctgattgac acacacaacc gcttactcct    480
tcagacagca gagcttgctg tggtacagcc aatggcagtt aatatttccg caaatggttt    540
tggatttgct atttgtcagc tcaatgttgt atataatgtg aaggcttctg ggtcttctag    600
aagacgaaga tctatccaaa atcaagaagc ctttgattta gatgttgctg taaaagaaaa    660
taaagatgat ctcaatcatg tggatttgaa tgtgtgtaca agcttttcgg gcccgggtag    720
gagtggcatg gctcttatgg aagttaacct attaagtggc tttatggtgc cttcagaagc    780
aatttctctg agcgagacag tgaagaaagt ggaatatgat catggaaaac tcaacctcta    840
tttagattct gtaaatgaaa cccagttttg tgttaatatt cctgctgtga gaaactttaa    900
agtttcaaat acccaagatg cttcagtgtc catagtggat tactatgagc caaggagaca    960
ggcggtgaga agttacaact ctgaagtgaa gctgtcctcc tgtgaccttt gcagtgatgt   1020
ccagggctgc cgtccttgtg aggatggagc ttcaggctcc catcatcact cttcagtcat   1080
ttttattttc tgtttcaagc ttctgtactt tatggaactt tggctgtgat ttatttttaa   1140
aggactctgt gtaacactaa catttccagt agtcacatgt gattgttttg ttttcgtaga   1200
agaatactgc ttctattttg aaaaaagagt tttttttctt tctatggggt tgcagggatg   1260
gtgtacaaca ggtcctagca tgtatagctg catagatttc ttcacctgat ctttgtgtgg   1320
aagatcagaa tgaatgcagt tgtgtgtcta tattttcccc tctcaaaatc ttttagaatt   1380
tttttggagg tgtttgtttt ctccagaata aaggtattac tttagaaaaa aaaaaaaaaa   1440
aaatcgaa                                                            1448

<210> 1041
<211> 1882
<212> DNA
<213> Homo sapiens

<400> 1041
acccacgcgt ccgctagccc tgcccggccc cggaggactt gcaacactcc gaggccagga     60
acgctccgtc tggaacggcg caggtcccag cagctggggt tccccctcag cccgtgagca    120
gccatgtcca accccagcgc cccaccacca tatgaagacc gcaaccccct gtacccaggc    180
cctcygcccc ctgggggcta tgggcagcca tctgtcctgc caggagggta tcctgcctac    240
cctggctacc cgcagcctgg ctacggtcac cctgctggct acccacagcc catgcccccc    300
acccacccga tgcccatgaa ctacggccca ggccatggct atgatgggga ggagagagcg    360
gtgagtgata gcttcgggcc tggagagtgg gatgaccgga aagtgcgaca cacttttatc    420
cgaaaggttt actccatcat ctccgtgcag ctgctcatca ctgtggccat cattgctatc    480
ttcacctttg tggaacctgt cagcgccttt gtgaggagaa atgtggctgt ctactacgtg    540
tcctatgctg tcttcgttgt cacctacctg atccttgcct gctgccaggg acccagacgc    600
cgtttcccat ggaacatcat tctgctgacc ctttttactt ttgccatggg cttcatgacg    660
ggcaccattt ccagtatgta ccaaaccaaa gccgtcatca ttgcaatgat catcactgcg    720
gtggtatcca tttcagtcac catcttctgc tttcagacca aggtggactt cacctcgtgc    780
acaggcctct tctgtgtcct gggaattgtg ctcctggtga ctgggattgt cactagcatt    840
gtgctctact tccaatacgt ttactggctc cacatgctct atgctgctct gggggccatt    900
tgtttcaccc tgttcctggc ttacgacaca cagctggtcc tggggaaccg gaagcacacc    960
atcagcccsg aggactacat cactggsgcc ctgcagattt acacagacat catctacatc   1020
ttttagctca ggaaggtaga agagatctgt gcccatgggt ctccttgctt caatcccttc   1080
ttgtttcagt gacatatgta ttgtttatct gggttaggga tgggggacag ataatagaac   1140
gagcaaagta acctatacag gccagcatgg aacagcatct cccctgggct tgctcctggc   1200
ttgtgacgct ataagacaga gcaggccaca tgtggccatc tgctccccat tcttgaaagc   1260
tgctggggcc tccttgcagg cttctggatc tctggtcaga gtgaactctt gcttcctgta   1320
ttcaggcagc tcagagcaga aagtaagggg cagagtcata cgtgtggcca ggaagtagcc   1380
agggtgaaga gagactcggt gcgggcaggg agaatgcctg ggggtccctc acctggctag   1440
ggagataccg aagcctactg tggtactgaa gacttctggg ttctttcctt ctgctaaccc   1500
agggagggtc ctaagaggaa ggtgacttct ctctgtttgt cttaagttgc actgggggat   1560
ttctgacttg aggcccatct ctccagccag ccactgcctt ctttgtaata ttaagtgcct   1620
tgagctggaa tggggaaggg ggacaagggt cagtctgtcg ggtgggggca gaaatcaaat   1680
cagcccaagg atatagttag gattaattac ttaatagaga aatcctaact atatcacaca   1740
aagggataca actataaatg taataaartt tatgtctaga agttaaaacc ctgtatggcc   1800
ccttccctag ttcttttttg gggttagtta tcagtctcct ttgtctgtct ctttcccctc   1860
ctaatcttga agttcaatga aa                                            1882

<210> 1042
<211> 500
<212> DNA
<213> Homo sapiens

<400> 1042
gaattcggca cgagcagcgc gcacttacca ccatgcagat ccaggtcgcg gggctgctgc     60
agtttgccgt gcccctcttc tccactgcag aggaagacct gcttgcaatc cagctcctgc    120
tgaactcctc agagtccagc cttcaccagc tgaccgccat ggtggactgc cgagggctgc    180
acaaggatta tctggacgct cttgctggca tctgctacga cggcctccag ggcttgctgt    240
accttggcct cttctccttc ctggccgccc tcgccttctc caccatgatc tgtgcagggc    300
caagggcctg gaagcacttc accaccagaa acagagacta cgatgacatt gatgatgatg    360
acccctttaa cccccaagcc tggcgcatgg cggctcacag tcccccgagg ggacagcttc    420
acagcttctg cagctacagc agtggcctgg gaagtcagac cagcctgcag cccccggccc    480
agaccatctc caacgcccct                                                500

<210> 1043
<211> 1061
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (992)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (998)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1021)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1051)
<223> n equals a,t,g, or c

<400> 1043
gccaggctgg atggagccca gagctgtggg tctcctaccc tcccatcccc tcattccagc     60
ttgatcttcc ttaagagact catacgcccc aaccccttgg tctgagtatc ttagattgtt    120
ctcgtggttc ctccrtcctt caccactgaa ggctgctgtt cattctctct ccgtctctgt    180
cccttattgc tctcacgtct gtctctgtca tcttttcact ccttgtccct cttactccgt    240
tctttggccc ccaatgaaag ctgagtcaga gacagacgct tcccctcagt tcccagtgcc    300
tcccttgggg gcccctcctt ggctgtatcc gtcagtggct ccaggctgcc gcgcgcaggc    360
ttagctcatt cctctgacct gccaggaagc agagagaccc acagagcagg agggaggcag    420
aaagtggaga cggacctgag cccgaggaag aggcaggcag aggctgaggc tgattccacc    480
ccagcctgcc tggacaaccc tccttagccg cagccccttc cagttcccta ggggttctgc    540
ccctccccct ctctggggca ccagcccccc agggtcctgc atcccaccat gtcgatggct    600
gtggaaacct ttggcttctt catggcaact gtggggctgc tgatgctggg ggtgactctg    660
ccaaacagct actggcgagt gtccactgtg cacggkaacg tcatcaccac caacaccatc    720
ttcgagaacc tctggtttag ctgtgccacc gactccctgg gcgtctacaa ctgctgggag    780
ttcccgtcca tgctggccct ctctgggtat attcaggcct gccgggcact catgatcacc    840
gccatcctcc tgggcttcct cggcctcttg ctaggcatag cgggcctgcg ctgcaccaac    900
attgggggcc tggagctctc caggaaagcc aagctggcgg ccaacgcagg gcccttccaa    960
attcttggcc ggtatctgcg ggatggtggc anctcctngt aagcttcaaa tcaccggatt   1020
nttcgaacct ttaaccggaa caataagagt nggccgctta a                       1061

<210> 1044
<211> 1329
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1297)
<223> n equals a,t,g, or c

<400> 1044
tcgacccacg acgtccggcc tcgggtgggc cggggttgct gcgccgtcct ccactactgg     60
ctactggcgc tgyagccatg cagcccccgc ccccgggccc gctgggcgac tgcctgcggg    120
actgggagga tctacagcag gacttccaga acatccagga gacccatcgg ctctaccgcc    180
tgaagctgga ggagctgacc aaacttcaga acaattgcac cagctccatc acgcggcaga    240
agaagcggct ccaggagctg gccctcgccc tgaagaaatg caaaccctcc ctcccagcag    300
aggccgaggg ggccgcacag gagctggaga accagatgaa agagcgccaa ggcctcttct    360
ttgacatgga ggcctatttg cctaagaaga atggattgta cctgagcctg gttctgggga    420
acgtcaacgt cacgctcctg agcaagcagg ctaagtttgc ctacaaggac gagtatgaga    480
agttcaagct ctacctcacc atcatcctca tcctcatctc cttcacttgc cgcttcctgc    540
tcaactccag ggtgacagat gctgccttca acttcctgct ggtctggtac tactgcaccc    600
tgaccatccg ggagagcatc ctcatcaaca acggctcccg gatcaaaggc tggtgggtgt    660
tccatcacta cgtgtccacc ttcctgtcgg gagtcatgct gacgtggccc gacggtctca    720
tgtaccagaa attccggaac caattcctct ccttttccat gtaccagagc ttcgtgcagt    780
ttctccagta ctactaccag agcggctgcc tctaccgcct gcgggcgctg ggcgagcggc    840
acaccatgga cctcactgtg gagggcttcc agtcctggat gtggcggggc ctcaccttcc    900
tgctgccttt tcttttcttt ggacacttct ggcagctttt taacgcgctg acgttgttca    960
acctggccca ggaccctcag tgcaaggagt ggcaggtgct tatgtgcggc tttcccttcc   1020
tcctcctttt cctcggcaat ttcttcacca ccctgagggt tgtgcaccac aagtttcaca   1080
gtcagcggca cgggagcaag aaggattgag gctgggcctt cccctgccgg cccagagggg   1140
cttctgtcct gtgtgttgtg ggaggggatg ggaggcgccc ctcgagtgtg cgtgtatcag   1200
ggggtctctt ctattctccc ttgggtttta tgggcgctgt gggccctgaa ggaagacctg   1260
ggcccagtgc cctcaataaa gagaggccca gaggtgnaaa aaaaaaaaaa aaaaagggcg   1320
gccgctcta                                                           1329

<210> 1045
<211> 1542
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1471)
<223> n equals a,t,g, or c

<400> 1045
cgctggcagt caacgctggt tcgctactga cgccaattgg caacccgcaa aatattctta     60
tctggggacg ttctggtctt tcgtttgccg gatttattgc ccaaatggca ccgctggctg    120
gcgcaatgat gctgacgctc ctgctcctgt gctggtgttg tttccctgga aaggcgatgc    180
aataccatac gggggtgcaa acaccggagt ggaaaccgcg gctggtgtgg agttgtctgg    240
ggctgtatat cgtctttctg acggcgctgg agttcaaaca agagctgtgg ggactggtga    300
ttgtggcggc aggctttgcg ctgctggcac gtcgcgtggt gctcagtgtg gactggacgc    360
tgctgctggt gtttatggcg atgtttatcg acgtccattt actgacccag cttccagcgt    420
tgcaaggcgt gttgggtaac gtgagtcatc tatctgaacc cgggttatgg ttaacggcaa    480
tcggtttatc gcaggtgatc agtaacgtgc cgagtaccat attgttgctg aactatgtgc    540
cgccgtcttt attactggta tgggcggtaa acgtaggtgg ctttgggtta ttacccggat    600
cgctggcaaa tttgattgcg ctacgtatgg cgaacgatcg ccgcatctgg tggcgtttcc    660
atctctattc aataccgatg ctgttgtggg cggcgttggt gggatatgtt ttgttagtta    720
tactcccggc caactagggt ctggcaaata aaaaaggcgg attatgagtc cgccttttgc    780
tttaagtttt gaagattaat tcagacgaac cggcatcccg gagcggtttt taatcgcttc    840
atcaagaaca acctggtcaa catctggctg accggtcact gtctgcacgc tcttcgtcag    900
ggtaattggc acaatttcct gaccttcaaa ctgggcttcg gtggtagaca gcgggttatg    960
gacttcaata taacggctgc cgtctggctc ggtggtcgct tttaccggct catcaataaa   1020
ctgtacgcgg gtaccgaccg gtactttctc gaacaggaat ttgatgtctt cgttacgcag   1080
acgcacacaa ccatgactta cacgcaggcc gataccgaag ttggcgttgg tgccatggat   1140
agcatacagg cgaccgatat agagtgcata cagccccatc gggttatccg gacctgccgg   1200
aacgacagcc ggaagcggtt ygcccgcagc gcggtactct gcgtgcattt tggcggtcgg   1260
cgtccaggtc gggcctgctt ttttacgctc aactttggtg gtccagttga taggcgtatc   1320
tttgcctaac tgaccaatgc cgatcggcag cacgataacg gtgttggtcc ctttcggata   1380
gtaataaaga cgcatctcag cactgttaat gacgatgcct tcatgaacgg tatccggcag   1440
gatcagctgc tgcggaatgt tcagtacagt naccgctttc ggcaggaagg tatccacacc   1500
cgggttcgct tccatcatat tggaaagccc catctggtac tc                      1542

<210> 1046
<211> 618
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (529)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (613)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (615)
<223> n equals a,t,g, or c

<400> 1046
agttggggac taccagcttt tgtggtgatt ctcctcatag ttattttgaa aggaatctat     60
catcagagca tgtcacagat ctatggactc attcatggtg acctgtgttt tattccaaac    120
gtctatgctg ctttgttcac tgcagctctt gttcctttga cgtgcctcgt ggtggtgttc    180
gtggtgttca tccatgccta ccaggtgaag ccacagtgga aagcatatga tgatgtcttc    240
agaggaagga caaatgctgc agaaattcca ctgattttat atctctttgc tctgatttcc    300
gtgacatggc tttggggagg actacacatg gcctacagac acttctggat gttggttctc    360
tttgtcattt tcaacagtct gcagggactt tatgttttca tggtttattt cattttacac    420
aaccaaatgt gttgccctat gaaggccagt tacactgtgg aaatgaatgg gcatcctgga    480
cccagcacag cctttttcac gcccgggagt ggaatgcctc ctgctggang ggaaatcagc    540
aagtccaccc agaatctcaa tcggtggtat ggaggaaggt gccacctgac tgggagagag    600
catccttcca aananggg                                                  618

<210> 1047
<211> 1782
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1697)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1702)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1729)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1741)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1774)
<223> n equals a,t,g, or c

<400> 1047
ccacgcgtcc gcgacgggag cgcgtggagt tncgttgggg gaaaagagtc cttttatgac     60
acattccata ctgtggctga catgatgtat ttctgccaga tgctggcagt tgtggaaact    120
atcaatgcag caattggagt cactacgtca ccggtgctgc cttctctgat ccagcttctt    180
ggaagaaatt ttattttgtt tatcatcttt ggcaccatgg aagaaatgca gaacaaagct    240
gtggttttct ttgtgtttta tttgtggagt gcaattgaaa ttttcaggta ctctttctac    300
atgctgacgt gcattgacat ggattggaag gtgctcacat ggcttcgtta cactctgtgg    360
attcccttat atccactggg atgtttggcg gaagctgtct cagtgattca gtccattcca    420
atattcaatg agaccggacg attcagtttc acattgccat atccagtgaa aatcaaagtt    480
agattttcct tttttcttca gatttatctt ataatgatat ttttaggttt atacataaat    540
tttcgtcacc tttataaaca gcgcagacgg cgctatggac aaaaaaaraa aaagatccac    600
taaaaagaaa gatttagatg gcttcttgcc agtttgagcc taatctgatt cttacagttt    660
taccttcttg aaccaatgta aaagtttttt taatgttaaa tgattaaatt ctcagtgagg    720
ctatcttcct tttccccagt aacattcctg aatttactgt tatcttattg tagtacttgc    780
atgacatgga ttcctgatat ctgatgagag gttcattctt gtgtattcag ttaatgacac    840
caaaaggctc agcccacccc aaccctatct catgttcagt ctgtctaata catgccagag    900
attttttttt caaaaagtgc tttatcccta caatgtactg acagttctta cagttgagat    960
ttgttctttt cagctattgc ttgtgaaaaa aagcaagact atgtcactct atagaaggct   1020
gttaaagtga ctcaggcagg aattaattat tctgtaccta aggggttact tgtttaatgg   1080
gatggcattg actttttgaa aatcaagtgg actgagtcat tgataaaaca tttctaagag   1140
tggggctaga gaacatactt tacatctgac atcctttggc ctaacaacat ctattattat   1200
agtgctcagc agtgtgggca ttgaagaggc gcagaatgct ttgaaagaaa ctaatcagaa   1260
tcttggaaca tcatgatcat gccattctta agtaaatcaa ctattttcaa cactgaagaa   1320
aaatgaaaca ttatttagaa aacaatgaga ttacaagttc caaactcagc caggaatgtg   1380
ggctcacacc tgtaatccca gcactttggg acacctaggt gggagcatcg cttgaagcca   1440
ggagttcaag accagcttgg gcaacgtagt gagaccccta tctctacaaa aaataaaaaa   1500
attagctggg tgtgatggca cacacctgtt gtcccagcta ctcaagaagc tgagatggga   1560
ggatcctgag ctcaggaggt caaggctgca gtgagccgag awtgtgccac tgcactgsag   1620
ctggggtgac agtgcaagac cctgtcttaa accaaaccaa accacacaca cacaaacaca   1680
catacacaca cacacanacg anggtccaaa tggtagcagg gatccaaang ggacacagta   1740
ngtagggtca aactgggcag ttacagtgta cagnctttga ca                      1782

<210> 1048
<211> 672
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (59)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (641)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (661)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (663)
<223> n equals a,t,g, or c

<400> 1048
cttggctcct cttctcacta tcagcagaga gctgttactg aacagtgaaa ggggaaggnt     60
tctttgtcaa tcccatcata actctgtcct tttggtcckc ctgcagatgc tccagtggct    120
ttraccgcta tcgccaggag tggatggact atggctgtgc acaggaggca gagggcagga    180
tgtgcgagga cttccaggat gaggaccacg actcagcctc ccctgacact tccttcagcc    240
cctatgatgg agacctcacc actacctcct cctccctctt catcgacagc ctcaccacag    300
aagatgacac caagttgaat ccctatgcag gaggagacgg ccttcagaac aacctgtccc    360
ccaagacaaa gggcactcct gtgcacctgg gcaccatcgt gggcatcgtg ctggcagtcc    420
tcctcgtggc ggccatcatc ctggctggaa tttacatcaa tggccacccc acatccaatg    480
ctgcgctctt cttcatcgag cgtagacctc accactggcc agccatgaar tttccgcagc    540
acctgamcat tccacctatg cggargtgga gcctcgggcc atgaaaagga aggctccatg    600
gaagctgaca atgctgaaaa acaccaatct ccctttgaaa nactttgaag gcacagaaaa    660
nanagttaaa gc                                                        672

<210> 1049
<211> 806
<212> DNA
<213> Homo sapiens

<400> 1049
ccatgtcttt gcaataggat aatataaaga atagtattaa aagtcagagg ctttactaat     60
ctacctatat gtattccatg gctaacaaac cctggcccct ttacatatga gctctggagg    120
ttcgcctggc tgcctcaggc ttgcagaagg ctgccccaat cacagagcct gggtaaggtg    180
gaacaggagg cagccccact cggcttttct gattgcatcc cacctgtttc tgagtgtgtt    240
ggtttggttt aattcttttc aagggttgga gttggaaagt gaaaacccta gacacttgct    300
gtggaatgtt tgcctggttg tattggtgtg tccctcttct tcactggcat gtcgctttca    360
agtgtaccaa aggacatttt gttctgttga aagccacagg accaaaagga aaatattgca    420
actatttgca aacatacttc cctacctata caagcagcca tatactaaaa agcactaaac    480
aagcacaaat gaacactaaa tagccttata ccaaaaagca ttcttgtaac tgtcagggca    540
tggtatgaat tccttcctct ttaagcagca acttaccaca ggcttggtgg ctttaagtaa    600
tatagcatta agcaaatggt cagttatttt ttaatgttga aaacttccaa gtgtgaataa    660
tacggacata gtttactacc ttttgctttt aatatacctg gttatctatt tccatttgaa    720
ataaaatgaa aggagacctc aaactgatgc tgagaagtag acaaaatcag ctctcagact    780
taactctccc caattaaaat agtttt                                         806

<210> 1050
<211> 523
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (519)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (522)
<223> n equals a,t,g, or c

<400> 1050
cacgaactcc caggaggcag cgcagcccct ggcatggggg cagcccaccc actgccgctc     60
ggtatgtctc cacaggctga cggggtacgg gatccaccac tgctttgcca ggagcatgat    120
gggccacgag gtgaaggtgc cgctcctgga gaacttctat gctgactact ataccacggc    180
cagcatcgcg ctggtgtcct gcctggccat gtgcgtggtg gtccgattcc tcgggcgcaa    240
gggaaggctg ctgctcttca tgatcctcac cgccctggcc tcgctcctgc agctcggcct    300
cctcaacctg attggaaagt acagccagca cccagactca gggatgartg acagcgtcaa    360
ggacaaattt tccatcgcgt tttccatcgt ggggcatgtt tgcctcccat gcggtgggga    420
cctcagcgtt ttcttctgtg cggaaatcac cccaacggtt attaaagttt tgccggcttg    480
ggctggttct tgccaccccg ggcttccggc attcttaann gna                      523

<210> 1051
<211> 762
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (300)
<223> n equals a,t,g, or c

<400> 1051
ggcagagggg aatcatggca gcatccaggc cattgtcccg cttctgggag tggggaaaga     60
acatcgtctg cgtggggagg aactacgcgg accacgtcag ggagatgcgc agcgcggtgt    120
tgagcgagcc cgtgctgttc ctgaagccgt ccacggccta cgcgcccgag ggctcgccca    180
tcctcatgcc cgcgtacact cgcaacctgc accacgagct ggagctgggc gtggtgatgg    240
gcaagcgctg ccgcgcagtc cccgaggctg cggccatgga ctacgtgggc ggctatgccn    300
tgtgcctgga tatgaccgcc cgggacgtgc aggacgagtg caagaagaag gggctgccct    360
ggactctggc gaagagcttc acggcgtcct gcccggtcag cgcgttcgtg cccaaggaga    420
agatccctga ccctcacaag ctgaagctct ggctcaaggt caacggcgaa ctsagacagg    480
agggtgagac atcctccatg attttttyca tcccctacat catcagctat gtttctaaga    540
tcataacctt ggaagaagga gatattatct tgactgggac gccaaaggga gttggaccgg    600
ttaaagaaaa cgatgagatc gaggctggca tacacgggct ggtcagtatg acatttaaag    660
tggaaaagcc agaatattga gttatttctt aacaagtttc gagagagaag ggagcaagac    720
aagagcaagc aacggctatt aaatgtcaca atcctttaat ta                       762

<210> 1052
<211> 1201
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (727)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1016)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1149)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1180)
<223> n equals a,t,g, or c

<400> 1052
ggagttcgga gcctaggagc cccccgcggc tgcggcgcag gtgccctcgg cctgagtcgg     60
gatggagctg cctgctgtga acctgaaggt gattctccta ggtcactggc tgctgacaac    120
ctggggctgc attgtattct caggctccta tgcctgggcc aacttcacca tcctggcctt    180
gggcgtgtgg gctgtggctc agcgggactc catcgacgcc ataagcatgt ttctgggtgg    240
cttgctggcc accatcttcc tggacatcgt gcacatcagc atcttctacc cgcgggtcag    300
cctcacggac acgggccgct ttggcgtggg catggccatc ctcagcttgc tgctcaagcc    360
gctctcctgc tgcttcgtct accacatgta ccgggagcgc gggggtttcc ttgggtcttc    420
tcaggaccgt agtgcctacc aracgattga ytcagcagag gcgcccgcag atccctttgc    480
agtcccagag ggcaggagtc aagatgcccg agggtactga agccagccac gctgcgcccg    540
gccctgcccc gggccttcct cgtgcctggg aggtcgttct agggatgctc ctgacctycg    600
tctcttggac ctaagatgga atgtgtcccc agctcargga ttgcctgaac caagaggcca    660
ggagccccca tgggccgccc agtaccatgc acactcctgt cccgaactcc ctgaggcytc    720
ccctccnttc agggcaccca tggttcccag gctggaamca gggtctctct ttamctycta    780
mcccatggtg gsaccacara ggccctcagc cgaktcctgs ctgagtgttg caakctcagg    840
cctttaagga ctgctgatgc cccctcaggc ctcccccaag tttgctgggc tttggtggaa    900
gccctgagag cttcaggtcc tgctcagccc gaggagcagt ctggcatggg agtgaggccc    960
cgtccttctc actgcctggt cacatggtgc ctagggatgc agggctggag gcagangtgt   1020
cagcaacact gtgaaccaac acaacttcag cctccctttt agagcacagc attaaagttt   1080
gggaatctgt aaaaaaaaaa aaaaaggggc gaagttattc cttaggaggt aattagttgg   1140
atggcgtgnt taaagtgtat ggaaaaaagg taccaattan gctgagaatc ctttcatgga   1200
a                                                                   1201

<210> 1053
<211> 773
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (76)
<223> n equals a,t,g, or c

<400> 1053
ttgcggtcag gcgattatta acgccgacga tgaagtgggc cgccgctggc tggcaaaact     60
gccggacgcg gttgcngtat caatggaaga tcatattaat ccgaactgtc acggacgctg    120
gttgaaagcg accgaagtga actatcacga cagcggtgcg acgattcgct ttagctcaag    180
ttggggcgat ggcgaaattg aaagccatct gatgggcgct tttaacgtca gcaacctgct    240
gctcgcgctg gcgacactgt tggcactcgg ctatccactg gctgatctgc tgaaaaccgc    300
cgcgcgtctg caaccggttt gcggacgtat ggaagtgttc actgcgccag gcaaaccgac    360
ggtggtggtg gattacgcgc atacgccgga tgcactggaa aaaccttaca ggcggcgcgt    420
ctgcactgtg cgggcaagct gtggtgtgtc tttggctgtg gtggcgatcg cgataaaggt    480
aagcgtccac tgatgggcgc aattgccgaa gagtttgctg acgtggcggt ggtgacggac    540
gataacccgc gtaccgaaga accgcgtgcc atcatcaacg atattctggc gggaatgtta    600
gatgccggac atgccaaagt gatggaaggc cgtgctgaag cggtgacttg cgccgttatg    660
caggctaaag agaatgatgt ggtactggtc gcgggcaaag gccatgaaga ttaccagatt    720
gttggcaatc agcgtctgga ctactccgat cgcgtcacgg tggcgcgtct gct           773

<210> 1054
<211> 948
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (856)
<223> n equals a,t,g, or c

<400> 1054
ggcagagggc catttcctgc aaagagccaa acccccattc ctctgtgccc ctcctctccc     60
accaagtgct ttataaaaat agctcttgtt accggaaata actgttcatt tttcactcct    120
ccctcctagg tcacactttt cagaaaaaga atctgcatcc tggaaaccag aagaaaaata    180
tgagacgggg aatcatcgtg tgatgtgtgt gctgcctttg gctgagtgtg tggagtcctg    240
ctcaggtgtt aggtacagtg tgtttgatcg tggtggcttg aggggaaccc gctgttcaga    300
gctgtgactg cggctgcact cagagaagct gcccttggct gctcgtagcg ccgggccttc    360
tctcctcgtc atcatccaga gcagccagtg tccgggaggc agaagatgcc ccactccagc    420
ctgcatccat ccatcccgtg tcccaggggt cacggggccc agaaggcagc cttggttctg    480
ctgagtgcct gcctggtgac cctttggggg ctaggagagc caccagagca cactctccgg    540
tacctggtcc tccacctagc ctccctgcag ctgggactgc tgttaaacgg ggtctgcagc    600
ctggctgagg agctgcgcca catccactcc aggtaccggg gcagctactg gaggactgtg    660
cgggcctgcc tgggctgccc cctccgccgt ggggccctgt tgctgctgtc catctatttc    720
tactactccc tcccaaatgc ggtcggcccg cccttcactt ggatgcttgc cctcctgggc    780
ctctcgcarg cactgaacat cctcctgggc ctcaagggcc tggccccagc tgagatctct    840
gcagtgtgtg aaaaanggaa tttcaacgtg gcccatgggc tggcatggtc atattacatc    900
ggatatctgc ggctgatcct gccaaaastc caaggccgga ttcgaact                 948

<210> 1055
<211> 785
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> n equals a,t,g, or c

<400> 1055
gccctcagtt ctctggccaa gaggagcaat tttcgtgcca tcagcaaaaa gctgaatttg     60
atyccacgtg tggnacggcg agtatgatct gaaagtgccc cgagacatgg cttacgtctt    120
crgtggtgct tatgtgcccc tgagctgccg aatcattgag caggtgctag agcggcgaag    180
ctggcagggc cttgatgagg tggtacggct gctcaactgc agtgactttg cattcacaga    240
tatgactaag gaagacaagg cttccagtga gtccctgcgc ctcatcttgg tggtgttctt    300
gggtggttgt acattctctg agatctcagc cctccggttc ctgggcagag agaaaggcta    360
caggttcatt ttcctgacga cagcagtcac aaacagcgct cgccttatgg aggccatgag    420
tgaggtgaaa gcctgatgtt tttcccggcc agtgttgaca tcttccctga acacattcct    480
cagtgagatg caggcatctg gcacccagct gctataacca agtgtccacc aactacctgc    540
taagagccgg gagcatggaa cgtgttggga tttagagaac attatctgag aaaagagttc    600
acttcctgct cccaggatat ttctcttttc tgtttatgaa gtacaaccca tgctgctaag    660
atgcgagcag gaagaggcat cctttgctaa atcctgtttg aatgtcattg taaataaagc    720
ctctgctctc agatgtaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagggggg    780
ggggc                                                                785

<210> 1056
<211> 853
<212> DNA
<213> Homo sapiens

<400> 1056
gcaagcaaac ctagagatca ctggccccaa ggtggcatct cctgggccac aaggaaaaaa     60
acgtgactac cagcgtctgg gatkgcccag cccggacgaa tgcctcaaac tccgctgggt    120
agagctgact gccatcgtga gtacctggct tgcagtttct tcaaaaaaca ttgacatcac    180
agaacacata gattttgcca cccctataca gcagccagca atggagcctc tttgcaatgg    240
caatctcccc acgagtatgc ataccctgga ccacttgcat ggggtttcca accgagccag    300
cctgcactac acaggggaga gtcagttaac agaggtatta caaaatctcg gcaaagacca    360
atatccacaa cagtcgcttg aacagattgg cacccgaatt gccaaagttt tggaaaagaa    420
ccagacgtcc tgggtcctct ccagcatggc agccctctac tggagggtga aaggccaagg    480
aaagaaggca atcgactgcc tccgccaggc tctgcactat gcgccacacc agatgaagga    540
tgtgcccctg attagcctgg ccaacatctt gcacaatgcc aagctctgga atgacgccgt    600
catagtagcc accatggcag tagagatcgc accacacttt gctgtgaacc acttcactct    660
gggcaatgtc tacgtggcaa tggaagaatt tgaaaaagca ctggtgtggt atgaatccac    720
attgaagctt cagcccgagt ttgtcccagc caagaaccga atccagacca tccagtgtca    780
cttaatgctg aagaagggac ggcgctctcc ttagtgcact tcttccttct ctctttctct    840
ttactcatgc tct                                                       853

<210> 1057
<211> 663
<212> DNA
<213> Homo sapiens

<400> 1057
gggaaactga ggcacagagg ggttaacttc tcccaggggg attgagctag tgagtagtgt     60
aacctgatat tggacccagg cagtctggct ccagggccaa tgcttgggtc cctgttcttc    120
tgcctctcag tatgcgaatg gccagtctgt ttctttaatt ggagtgagtg gcacttggca    180
cacccacaca gccaccttaa acattgtggg aaatcaagtc caagtatctc aagtaacagt    240
acaacawtcc atatcrggaa aaacagctta gggcttgact tcattatggt tttggctgcc    300
attttatgca ttctgagtag aagaaacatt cctcctagcg cccccacctt gtctttaaca    360
ttccgcagtg gaagttcctc aaagctctcc gttttgaaag catcctctat gattaccagc    420
cactaaattg catctgccac cgagggccca atgggctttg aacctgttat tcttgggaaa    480
ttcaagctgc gagggagaga gagaacgttg tacacgtgtg cagctgtgct ttggagtasa    540
agaagtaatc gtatgtgtct gtgtgttttt tatgggggta ggggaagggt atattaatta    600
acccaactga gaaggagatg actgtgttcc aggaaggagc caatgaaatg agtttgcttt    660
aaa                                                                  663

<210> 1058
<211> 2062
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1379)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2047)
<223> n equals a,t,g, or c

<400> 1058
gctcgggggc ctgggctgcc cctgacaccc cttctgggcg atggtgcanc ccaagggcgc     60
ctccatcccc cgccgctgcc gctaacccgg gtcccctacc cccacttctc tcagttcctg    120
gcatgaggag agaagaccct gctctggtgg agctgacaag accaaggaga tccagtctgt    180
ctacatccgt gagggcatgg ggcagctggt ggctgctaac gatgggtgac gctggtgaag    240
tggcccaggg aagtgcacat gtctctccct gctcttccag ggtgattttt ttgatgtttg    300
gctcttggtc cttgtttcca ctggctttcc atccccatgg ggcagaaaca gtggctcctg    360
ggagcagaaa aggaattgag gtgggcaggc agaagagcct ggattgctca ctgttttggg    420
aaacttacat gttgagatct acagagatcc aggaaaccaa agccctgctg agcagagcca    480
ttttgtggct atttctggar gcccaggart gtggctgcaa gagaaaaggg gctggaggaa    540
gatccggagg gcaggggtgt tccctctgct gatgatggat gcccctaaca cctgtgccta    600
acacccctac tgaaccccac agctccagcc ttagtttttg gagtcaagtg ttaaaggttt    660
ctggccagag gaattggggt cttgccatcc ctgcaatagc ccttttatgg gctctgggag    720
acagctttag ggaataaatg gggattttcc cctttttcta cccactcctt tgcttcctcc    780
aagacttacc caactccttc cccctcagag aaccaaatag cctgaggaag caggagagtt    840
cctggttatg gcagtttctt ggtgatttgg ggcttcaaga cagtaggtga gagatgctgt    900
caggacgtat cttcttcata ccaaagtcac tggtcctttc tcagcctctc tcgtgctttt    960
ctcctaatga ccatattttt gccaaaaatt gggatatgtt atctgacaga ccagaatatt   1020
tgaagtttgg gctgtcctga aagtctggac tttggtggta ccctcctccc ccagcccatc   1080
tgttgcacat tatactccgt gtgttcttca actttcggcg cccttattcc cctgccttcc   1140
tggcttgatt gaaggaaagc ttgaaaaggc gcagagccct atacctcatt tcctccatga   1200
taaaaggatc caagtgaggc cctgtcacag cctgtgggta ggggatgcgg cgggatcctc   1260
attgccatgg tactcaaagg tagaagagcc tggagtttgt tgcttctctt tgctattctt   1320
tcatatcctc ttgggcctgg tgattaatta gcaattctca ttcctctcag ccaaaggcnt   1380
gcactgggct ttatttgtct ttttttattt tttaagcact gcctgccaga gatgggcctg   1440
gggctgatga ggaccttagc gctgctcgtt ctccttttct gttcatgcac acattcctcc   1500
atggggtggg gaaggcaggc atggggtgtg gccctcggag aagttaggag tcccccagct   1560
caagatacag tggcaaagac ctagtggtcc cctaccccca cttctctcag ttcctggcat   1620
gaggagagaa gaccctgctc tggtggagct gacaaccttt gaggctggga ggagagcagc   1680
ctctgggcat cgttcccagt gtccctcaca ctaaaacggc gtagatggca accccccacc   1740
cccaccccgc tgctcaactc ttgtgtttgt tgttctgttt gccccattta tctgttgctg   1800
tttttgtgtt gtcttcccct gctccgcatt ttgtaaaatg gcccctgggg gagtgttttt   1860
gctggatctg ctccctctcg ctctctcact ccactacttt ttggaacaaa gtgatggcag   1920
aatgcggtgg tggtgggggt cttttgtact gttggattaa taaaatgatt ttaaaatccc   1980
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagggcggc cgctctaaaa   2040
aatcccncaa ggggcccaag ct                                            2062

<210> 1059
<211> 809
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (466)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (645)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (676)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (686)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (772)
<223> n equals a,t,g, or c

<400> 1059
gctgccggtg tcgtctttgc ttcagccgca gtcgccactg gctgcctgag gtgctcttac     60
agcctgttcc aagtgtggct taatccgtct ccaccaccag atctttctcc gtggattcct    120
ctgctaagac cgctgccatg ccagtgacgg taacccgcac caccatcaca accaccacga    180
cgtcatcttc gggcctgggg tcccccatga tcgtggggtc ccctcgggcc ctgacacagc    240
ccctgggtct ccttcgcctg ctgcagctgg tgtctacctg cgtggccttc tcgctggtgg    300
ctagcgtggg cgcctggacg gggtccatgg gcaactggtc catgttcacc tggtgcttct    360
gcttctccgt gaccctgatc atcctcatcg tggagctgtg cgggctccag gcccgcttcc    420
ccctgtcttg gcgcaacttc cccatcacct tcgcctgcta tgcggncctc ttctgcctct    480
cggcctycat catctacccc accacctatg tccagktcct gtcccacggc cgttcgcggg    540
accacgccat cgccgcacct tcttctcctg catcgcgtgt gtggcttacg ccaccgaagt    600
ggcctggacc cgggcccggc ccggcgagat cactggctat atggncaccg tacccgggct    660
gctgaaggtg ctgganacct tsgtgnctgc atcatcttcg cggtcattaa gcgamcccaa    720
cctgtacarc amcagcggcc tgatgtcgtg gcggggacgc attgttatct ancgggcatc    780
ggcaatcctg gttggaacct ggggggaag                                      809

<210> 1060
<211> 1960
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1940)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1941)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1947)
<223> n equals a,t,g, or c

<400> 1060
ctccgggctc tgggtggcgg cggctgtgag cggcggcact gcggcgcagc ggcggctggc     60
cctgtcggcc gcgggatgag gaagcggacc gagcccgtcg ccttggagca tgagcgctgc    120
gccgccgcgg gctcgtcctc ctccggctcg gccgccgcgg cgctggacgc cgactgccgc    180
ctgaagcaga acctacgcct gacgggcccg gcggcggctg agccgcgctg cgcagccgac    240
gcgggaatga agcgggcgct gggcaggcga aagggcgtgt ggttgcgcct gaggaagata    300
cttttctgtg ttttggggtt gtacattgcc attccatttc tcatcaaact atgtcctgga    360
atacaggcca aactgatttt cttgaatttc gtaagagttc cctatttcat tgatttgaaa    420
aaaccacagg atcaaggttt gaatcacacg tgtaactact acctgcagcc agaggaagac    480
gtgaccattg gagtctggca caccgtccct gcagtctggt ggaagaacgc ccaaggcaaa    540
gaccagatgt ggtatgagga tgccttggct tccagccacc ctatcattct gtacctgcat    600
gggaacgcag gtaccagagg aggcgaccac cgcgtggagc tttacaaggt gctgagttcc    660
cttggttacc atgtggtcac ctttgactac agaggttggg gtgactcagt gggaacgcca    720
tctgagcggg gcatgaccta tgacgcactc cacgtttttg actggatcaa agcaagaagt    780
ggtgacaacc ccgtgtacat ctggggccac tctctgggca ctggcgtggc gacaaatctg    840
gtgcggcgcc tctgtgagcg agagacgcct ccagatgccc ttatattgga atctccattc    900
actaatatcc gygaagaagc taagagccat ccattttcag tgatatatcg atacttccct    960
gggtttgact ggttcttcct tgatcctatt acaagtagtg gaattaaatt tgcaaatgat   1020
gaaaacgtga agcacatctc ctgtcccctg ctcatcctgc acgctgagga cgacccggtg   1080
gtgcccttcc agcttggcag aaagctctat agcatcgccg caccagctcg aagcttccga   1140
gayttcaaag ttcagtttgt gccctttcat tcagaccttg gctacaggca caaatacatt   1200
tacaagagcc ctgagctgcc acggatactg agggaattcc tggggaagtc ggagcctgag   1260
caccagcact gagcctggcc gtgggaagga agcatgaaga cctctgccct cctcccgttt   1320
tcctccagtc agcagcccgg tatcctgaag ccccrggggg ccggcacctg caatgctcag   1380
gagcccagct cgcacctgga gagcacctca gatcccaggy ggggaggccc ctgcaggcct   1440
gcagtgcccg gaggcctgag catggctgtg tggaaagcgt gggtggcagg catgtggctc   1500
tccttgccgc ccctcaacct gagatcttgt tgggagactt aatggcagca ggcagccatc   1560
actgcctgst tgatgctgca ctgagctgga cagggggagt ccgggcaggg gactcttggg   1620
gctcgggacc atgctgagct ttttggcacc acccacagag aacgtggggt ccaggttctt   1680
tctgcacctt cccagcacat gcagaatgac tccagtggtt ccatcgtccc ctcctgccct   1740
gtgtacctgc ttgcctttct cagctgcccc acctcccctg ggctggccca ctcacccaca   1800
gtggaagtgc ccgggatctg cacttcctcc cctttcacct acctgtacac ctaacctggc   1860
cttagactga gctttattta agaataaaat cgtggtggtg gtcaaaaaaa aaaaaaaaag   1920
ggggccgctt aagggtccan nttaagnaag gggaattgga                         1960

<210> 1061
<211> 1127
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1104)
<223> n equals a,t,g, or c

<400> 1061
aatccccctc tggcgcacat ttggttccgt gctggggctg atggcatttt tctacttctt     60
cgcccgtttg acgctgtttt gcgcggcgtg gattgccacc gccgaatata aagacgaccc    120
gcgaatgccg gggaaaacgc agccttaaaa targccggat gcggcgtaaa cgccttatcc    180
ggcatacgat tttattcggc ctggctcccc gtaggccgga taagatgcgc cagcatcgca    240
tccggctata atgcgcacat aacctcttga aactcgtccc cagagcctct tcagccatct    300
atttgggagc aaacaatttc attccaactc ataaccccag catataaatc cagttggtaa    360
cttttattta acctgaaacc agttttatcc actatttata aaattatgtg aagcatttca    420
tagaagaaaa atcactggcc taaacattat cccctttttg cctgattttt gaccatttcc    480
gcgatttgtt acacattgaa atatcacttt tgctgtgcgt aatatggcta ttcgttagcc    540
aaaaaataag aaaagattat gcaagcaaca gccacaacac tcgaccacga gcaagaatac    600
acgccgatca actcgcgtaa taaagtcctt gtcgcctctc tcattggcac agccattgag    660
ttcttcgact tttacattta cgccactgcg gccgttattg tgtttccgca tatcttcttc    720
ccgcagggcg atcctacggc agcaacgcta cagtcgctcg ccaccttcgc catcgccttc    780
gtcgcgcgcc ccattggctc tgccgttttt ggtcattttg gcgatcgcgt tgggcgtaaa    840
gcgacgctgg tcgcctcgtt gctaacgatg gggatttcga ccgtggtgat tggtctgctg    900
ccgggctatg ccacgattgg tattttcgcc ccgctgctgc tggcgctggc tcgatttggt    960
cagggtctgg gcttaggcgg sccggtaccc aattcgccct atagtgagtc gtattacaat   1020
tcactggccg tcgttttaca acgtcgtgac tgggaaaacc ctggcgttac ccaacttaat   1080
cgccttgcag acatcccctt tcgncaagct ggcgtaatag cgaagag                 1127

<210> 1062
<211> 610
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (37)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (227)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (585)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (597)
<223> n equals a,t,g, or c

<400> 1062
cgganaatcn tcctcactaa agttgaacaa aagctgnagc tccaccgcgg tggcggccgc     60
tctagaacta gtggatcccc cgggctgcag gaattcggca cgagcggcgt tggtccggtg    120
cgtcctgttc tacagctatg gccgggccag ctgcagcttt ccgccgcttg ggcgccttgt    180
ccggagctgc ggccttaggc ttcgcttcct acggggcgca cggcgcncaa ttcccagatg    240
cctacgggaa ggagctgttt gacaaggcca acaaacacca cttcttacac agcctggccc    300
tgttaggggt gccccattgc agaaagccac tctgggctgg gttattgcta gcttccggaa    360
cgaccttatt ctgcaccagc ttttactacc aggctctgag tggagacccc agcatccaga    420
ctttggcccc tgcgggaggg accctgctac tcttgggctg gcttgccttg gctctttgag    480
ctcccttttg cttaattact gggttttctg ggcagttttt tttttaaaga gttggagtaa    540
gaagaggatt aaaaaggaaa ggcaaataaa aaaaaaaaaa aaaanctcgg ggggggnccc    600
ggaaccaaat                                                           610

<210> 1063
<211> 1548
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (90)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1540)
<223> n equals a,t,g, or c

<400> 1063
aggtggccac ggccctggga ctcaaatccc tcaccaagca cctgcccccc ttggtcggca     60
gatttgtgcc ctttgcagca gtggcagctn caactgcatt caacatcccc ctggatgagg    120
cagagagagc tgcaggtggg catcccggtg gctgatgagg caggtcagag gcttggctac    180
tcggtgactg cagccaagca gggaatcttc caggtggtga tttcaagaat ctgcatggcg    240
attcctgcca tggccatccc accactgatc atggacactc tggagaagaa agacttcctg    300
aagcgccgcc cctggctggg ggcacccctg caggtgggac tggtgggctt ctgcctggta    360
tttgcaaccc ccctgtgctg tgccctattc ccccagaaga gctccataca cataagcaac    420
ctggaaccag agctgagagc tcagatccat gagcaaaacc ccagcgttga agtggtctac    480
tacaacaagg ggctttgagg agggtcagcc tctgtcccct ccctcacttc cttgggctgc    540
tgctttagtg gagtcatgtc acccctacca cttggctatc tgcctagcac tgggcagggg    600
ccttggtggg cagatggcaa ttgagggtag caacctatta gggtggggga gggacctcca    660
taaggctttt cctcccttct ctggtttcaa agatcagagc acataacccc tcctgtgctt    720
gagtgtccat gcatatacat acatgataca catgtgtatg tgtacattgg gtcctgaaag    780
ctagaagcag gcatgctagc ctagtatgtt ctgacatctg gcttcccttc tcagcctcat    840
gtccacctgc ctgccagcca ggctacaggt gtgacttcct tctctaaact gttacaccag    900
ccaagttatt tttgatggca cctcatccct tctagaaata ggaggagccc caggatctca    960
ggacagagac ttatagacac tagtaggaca aagcgggctg aatccttcag gtttctgata   1020
cctagctccc caagctgact gggctggcag aggagaacat gttgagacaa gggaggcagg   1080
ggacttatgc atccctcagt gccatccctt gtatcctggr atagctccat ttcccctcct   1140
cctctctacc agacaaagga gtgcctgtkt cctgtackgs cctcgctgtc tcccccacca   1200
ccctacttga cagcgtgggc atcttcaggc acagccttgg gagttcctgg tgtgctctga   1260
catcatgacc tcaaatctaa atcctccaat cccaactccc tttcccaaac aaaaagccac   1320
agaggcagag caagcattcc cctttaagag cttccactgc accccctccc aagggacaca   1380
gcggtaggaa tggtgcttaa actccacagg tatcagagag ggtgtaacta ggacatcctc   1440
aagggcagct aggccccgaa tgtacaatgt taagacaggg aattttgtgt tccattgact   1500
tttttttttt tttaaagggg tttcactatt ttgcccaggn tggagtgc                1548

<210> 1064
<211> 990
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (898)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (906)
<223> n equals a,t,g, or c

<400> 1064
tcatgaaggt gggttcacca tgccccagac gccagaaagt cagccgttga tcaatgaagg     60
ctgagaccat gatgcttggg cttaggatct tgaggcctgt cacatgggca gcatgtgcac    120
aggggacaga gtattcctct agcacacgca gctggggtac cagcccagcc tctyccacag    180
cctcttctag ctgtagcatc tccacagcaa gcacgaagac atggagggat ccatcttcac    240
tgccactggc cacgagatgg tggccctcac gggtgggcaa ggtgtgcagg ctgttgatac    300
cacagctgtg ggcctggaga gtcagggagg gggtgccaag ccggtaggga agcccaggat    360
ccactggagg ctccaggaca gtggagtcat ggtctagcat ggtggtgaga tcccagaaag    420
ccaggctgcc atcagtagct gcgctgcaca ggaggagcct ccgcctctgg ttgggtgcct    480
cgtgtgtaaa ggagtggacc ttgaggacac atcgcttatg gtggaaggtt tcagcaagga    540
gctgcagaat ccgcccagaa tcctgcaaaa gaaagagcct tacggcccca tcactacagg    600
ctgcagccac aagggggcca aggccgggct ggtcaagttc acacacagca agggacatgt    660
acctggtctc tgggtctacc ttaaccatcc gatgccgatt gcgttgccgg tcccaatact    720
catctagccg gtgggacgaa aggtgcatga catggcaggc gaggcggctt ggggtgctgg    780
ggtccggagt aaccatgatg ctgaagcagt gcatctcagc ccgccccccc gcagacacca    840
catgggcagt caggcctggc tgaggatcct gagggccacc tggggtgcca atgccccnca    900
cagccncagc acgtaccgag gagatatggt tacaaacagc tgtgagtgcg tgggctgagc    960
ctgtggttgt agggagtgct aggacacagc                                     990

<210> 1065
<211> 2227
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (543)
<223> n equals a,t,g, or c

<400> 1065
gcagcagcct gtctattggg acagcttggt cagcaagggg tgacctttga cctccagccc     60
atggaatgra tggctgcagc cacacatgcc ttgtctgccc ctgcagaggt tcggttgact    120
ccaccaggta gttgtggatt ctatgatggc ctccttatcc ttctgttgca gctcctcact    180
gagcagggga aggctagcct aatcagggat atgtccagtt cagaaatgtg gaccgttttg    240
tggcaccgct tctccatggt cctgaggctc cccgaggagg catctgcaca ggaaggggag    300
ctttcgctat ccagtccacc aagccctgag ccagactgga cactgatttc tccccagggt    360
atctttctat cacatggaag tatcctcatg tccatcctga agcatctgct ttgccccagc    420
ttctgaatca actgcgccag gcgcctcatg ggtctgagtt tctccctgtc gtggtgctct    480
ctgtctgcca gctcctttgc ttccctttgc gctggacatg gatgctgacc tccttataga    540
tgncttggcc gacctcaggg actcagaagt tgcagcccat ctgctgcagg tctgctgcta    600
ccatcttccg ttgatgcaag tggagctgcc catcagcctt ctcacacgcc tggccctyat    660
ggatcccacc tctytcaacc agtttgkgaa cacagtgtct gcctccccta gaaccatcgt    720
ctcgtttctc tcagttgccc tcctgagtga ccagccactg ttgacctccg accttctctc    780
tctgctggcc catactgcca gggtcctgtc tcccagccac ttgtccttta tccaagagct    840
tctggctggc tctgatgaat cctatcggcc cctgcgcagc tcctgggcca cccagagart    900
tctgtgcggg cacacactta taggctcctg ggacacttgc tccaacacag catggccctg    960
cgtggggcac tgcagagcca gtctggactg ctcagccttc tgctgcttgg gcttggagac   1020
aaggatcctg ttgtgcggtg cagtgccagc tttgctgtgg gcaatgcagc ctaccaggct   1080
ggtcctctgg gacctgccct ggcagctgca gtgcccagta tgacccagct gcttggagat   1140
cctcaggctg gtatccggcg caatgttgca tcagctctgg gcaacttggg acctgaaggt   1200
ttgggagagg agctgttaca gtgcgaagta ccccagcggc tcctagaaat ggcatgtgga   1260
gacccccagc caaatgtgaa ggaggctgcc ctcattgccc tccggagcct gcaacaggag   1320
cctggcatcc atcaggtact ggtgtccctg ggtgccagtg agaaactatc cttgctctct   1380
ctggggaatc agtcactgcc acacagcagt cctaggcctg cctctgccaa acactgcagg   1440
aaactcattc acctcctgag gccagcccat agcatgtgat tccagattcc tgcggtccag   1500
cctccaactt tggttgccag ctctttctta ttctactaca caagccgcca actcaactga   1560
gagctaaaga gactagaaaa gagataagct gccaactcaa ctgagaacaa gaaactagaa   1620
gagatttata tataaagctt cttccttctc ccagatgcag gatgttttca accagtaaat   1680
tttattgctg ttggtgccag agaagagtcc tttcttctct acatccaggg gccttttctc   1740
caataatgtg cctttaactc tagggacctg cctcacggac cttagggaaa aacctcaacc   1800
tgaaagatct cttcctttct ggagctcctt taatcttccc agcaggtttt tgccttagac   1860
gtgctggccc caggacagtg atgaagacag agcctgtctc agctctaggc tgtggggatc   1920
aatgccatca gtccctgtta ttgagggatt atcccttagc caacattcct atctgtgggt   1980
gggcgtggag agtgtatctt tttttggggt gtgtgtgtat atgtgtgtgt gtatgtgtgt   2040
gtgtgtttaa tagttctgtt tgtaaactct tttaataaaa gttgtgcctc accatacttg   2100
aagctcccag gacaagggtt gagaggctca acccctcttt cagcttctat gtggtgttgg   2160
aggtgctggt atcgtgttca cacaaraaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2220
aactcga                                                             2227

<210> 1066
<211> 555
<212> DNA
<213> Homo sapiens

<400> 1066
ggccctttga tgggcatatg cagaattcag ggagaggcaa grasccttgg gagccacttc     60
ggcagaarca garcttggac gttggtgawg ggagcccagt gaccccagcc agcctttctg    120
gctgagcgac tgcactggca tgaaaccaag atggggttcg gctcctgagg tttcctcctt    180
cctgcccctg attgcttttc ccacctcact gtctttcccc tactcccacc agtctgctgt    240
atggggctcc tgcccttgcc cacttcttac ctttccattt gtctccttcc cttcatcgac    300
ccgaagcatc ttcctcatcc tccttggara ratggtttgc tggttcacgt gtatctctca    360
ctccaaaact atggccaaaa tcctgtgtaa ttatttactt agtaaarata tttgttcctg    420
ctctctcagt ttttatagca gtgatgtgaa tcatttctat ttcctcactt taaaggaaaa    480
tgcttttatt attttaaaga aaattaatta aaacttcatt ttctttaaag gaaattaaaa    540
tatctatttt cttat                                                     555

<210> 1067
<211> 785
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (25)
<223> n equals a,t,g, or c

<400> 1067
ancttnaggg ggcgnatcaa anggnaatct tccaataaag ywtgagctgt tggaatccca     60
actcagagta gcctctttgc aagacatgtc ttgccaacta ctggtgaatg ctgaaggaac    120
agactgttta gaagccaaag aaaaagtcca tgttattgga aatcggctca aacttctctt    180
gaaggaggtc agtcgtcata tcaaggaact ggagaagtta ttagacgtgt caagtagtca    240
gcaggatttg tcttcctggt cttctgctga tgaactggac acctcagggt ctgtgagtcc    300
cacatcagga aggagcaccc caaacagaca gaaaacgcca cgaggcaagt gtagtctctc    360
acagcctgga ccctctgtca gcagtccaca tagcaggtcc acaaaaggtg gctccgattc    420
ctccctttct gagccagggc caggtcggtc cggccgcggc ttcmtgttca gagtcctccg    480
agcagctctt ccccttcagc ttctcctgct cctcctcatc gggcttgcct gccttgtacc    540
aatgtcagag gaagactaca gctgtgccct ctycaacaac tttgcccggt cattccaccc    600
catgctcaga tacacgaatg gccctcctcc actctgaact aagcagatgc catctgcaga    660
agtgctggta gcataaggag gatcgggtca taagsaatyc caaactacca acaagaggac    720
cttgatcttg gcgaaagccc tcggtgtggc aagctttagc ccttcttcag atcacatgtg    780
tgcaa                                                                785

<210> 1068
<211> 1011
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (996)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1006)
<223> n equals a,t,g, or c

<400> 1068
ggtggcaggc aggcaggctg gccccgggga cttctctctg gccctgctcc ctccgagcgc     60
tccgccgttg cccgcctggc ccctacggag tccttagcca ggatggaggc tgttgtgaac    120
ttgtaccaag aggtgatgaa gcacgcagat ccccggatcc agggctaccc tctgatgggg    180
tcccccttgc taatgacctc cattctcctg acctacgtgt acttcgttct ctcacttggg    240
cctcgcatca tggctaatcg gaagcccttc cagctccgtg gcttcatgat tgtctacaac    300
ttctcactgg tggcactctc cctctacatt gtctatgagt tcctgatgtc gggctggctg    360
agcacctata cctggcgctg tgaccctgtg gactattcca acagccctga ggcacttagg    420
atggttcggg tggcctggct cttcctcttc tccaagttca ttgagctgat ggacacagtg    480
atctttattc tccgaaagaa agacgggcag gtgaccttcc tacatgtctt ccatcactct    540
gtgcttccct ggagctggtg gtggggggta aagattgccc cgggaggaat gggctctttc    600
catgccatga taaactcttc cgtgcatgtc ataatgtacc tgtactacgg attatctgcc    660
tttggccctg tggcacaacc ctacctttgg tggaaaaagc acatgacagc cattcagctg    720
atccagtttg tcctggtctc actgcacatc tcccagtact actttatgtc cagctgtaac    780
taccagtacc cagtcattat tcacctcatc tgggatgtat ggcaccatct tcttcatgct    840
gttctccaac ttctggtatc actcttatac caagggcaag cggctgcccc gtgcactyca    900
caaaatggag ctccaggtat tgccaaggtc aaggccaact gagaagcatg gcctagatag    960
gcgcccacct aagtgcctca ggactgcacc ttaggnaagt gtcaantcag t            1011

<210> 1069
<211> 1330
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1265)
<223> n equals a,t,g, or c

<400> 1069
aattcggcmc agcagatgag gaagtggcag gcaggcaggc tggccccggg gacttctctc     60
tggccctgct ccctccgagc gctccgccgt tgcccgcctg gcccctacgg agtccttagc    120
caggatggag gctgttgtga acttgtacca agaggtgatg aagcacgcag atccccggat    180
ccagggctac cctctgatgg ggtccccctt gctaatgacc tccattctcc tgacctacgt    240
gtacttcgtt ctctcacttg ggcctcgcat catggctaat cggaagccct tccagctccg    300
tggcttcatg attgtctaca acttctcact ggtggcactc tcmctctrtg cttccctgga    360
gctggtggtg gggggtaaag attgccccgg gaggaatggg ctctttccat gccatgataa    420
actcttccgt gcatgtcata atgtacctgt actacggatt atctgccttt ggccctgtgg    480
cacaacccta cctttggtgg aaaaagcaca tgacagccat tcagctgatc cagtttgtcc    540
tggtctcact gcacatctcc cagtactact ttatgtccag ctgtaactac cagtacccag    600
tcattattca cctcatctgg atgtatggca ccatcttctt catgctgttc tccaacttct    660
ggtatcactc ttataccaag ggcaagcggc tgccccgtgc acttcagcaa aatggagctc    720
caggtattgc caaggtcaag gccaactgag aagcatggcc tagataggcg cccacctaag    780
tgcctcagga ctgcacctta gggcagtgtc cgtcagtgcc ctctccacct acacctgtga    840
ccaaggctta tgtggtcagg actgagcagg ggactggccc tcccctcccc acagctgctc    900
tacagggacc acggctttgg ttcctcaccc acttcccccg ggcagctcca gggatgtggc    960
ctcattgctg tctgccactc cagagctggg ggctaaaagg gctgtacagt tatttccccc   1020
tccctgcctt aaaacttggg agaggagcac tcagggctgg ccccacaaag ggtctcgtgg   1080
cctttttcct cacacagaag aggtcagcaa taatgtcact gtggacccag tctcactcct   1140
ccaccccaca cactgaagca gtagcttctg ggccaaaggt cagggtgggc gggggcctgg   1200
gaatacagcc tgtggaggct gcttactcaa cttgtgtctt aattaaaagt gacagaggaa   1260
accanaaaaa aaaaaaaaaa aaactcgagg ggggcccgta cccaaatcgc cggtatgatc   1320
gtaaacaatc                                                          1330

<210> 1070
<211> 724
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (623)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (688)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (697)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (719)
<223> n equals a,t,g, or c

<400> 1070
agcattgggc tcatgttcta cctggctaac gtctgtggct gtgccgtctc cctcctgggg     60
ctggtggagt ctgtgcttga tgtcttcggg gccgatgcca cagggcccag tgggctccgg    120
gtcctgcccc agggctacgg ctggaacctg ctgtatggct ccctgctgct gggccttgtg    180
ggtggggtct gcaccctggg agccggcctc tatgcccggg cctcattcct cacattcctg    240
ctggtctctg gctccctggc ctctgtgctc atcarttttg tggctgtggg gccgarggac    300
atccgcttga ctcctargcc tggccccaat ggctcctccc tgccgccccg gtttggccac    360
ttcaccggct tcaacagcag taccctgaag gacaacttgg gcgctggcta tgctgaggac    420
tacaccacgg gagccgtgat gaattttgcc agcgtctttg ctgtcctctt taacggctgt    480
acaggcatca tggctggggc caacatgtca ggggagctga aggaccccag ccgggcgatc    540
cctctgggca cgatcgtcgc cgtcgcctac amcttcttsg tctatgtcct gcttttcttt    600
tctcagttca cttgtgacag ganctgctgc aagaagatat ggggtcttcg gggcaataag    660
cttttggccc caactggtgt ttaatcgnaa ctatccnaaa gggtttaagg gtccatnanc    720
tcgc                                                                 724

<210> 1071
<211> 376
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (371)
<223> n equals a,t,g, or c

<400> 1071
gagccacatg cccccgagct ggatccagtg gtggagcacc tcgaactggc ggcaaccgct     60
gcagcgcctg ctgtggggtc tggaggggat actctacctg ctgctggcac tgatgttgtg    120
ccatgcactc ttcaccactg gctcccacct gctgagctcc ttgtggcctg tcgtggccgc    180
ggtgtggcgc cacctgctac cggctctcct gctgctggtg ctcagtgctc tgcctgccct    240
cctcttcacg gyctccttcc tgctgctctt ctccacactg ctgagccttg tgggcctcct    300
cacctmcatg actcacccag gcgacactca ggatttggat caatagaagg gcaaccccat    360
cccactgctg ngtctg                                                    376

<210> 1072
<211> 555
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (484)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (511)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (523)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<400> 1072
gcccacgcgt ccgcggggac tgaagatggc gccgcgaggt aaacggttgt cctccacccc     60
gctggaaatc ctgttctttc tgaacgggtg gtataatgct acctatttcc tgctggaact    120
tttcatattt ctgtataaag gtgtcctgct accatatcca acagctaacc tagtactgga    180
tgtggtgatg ctcctccttt atcttggaat tgaagtaatt cgcctgtttt ttggtacaaa    240
gggaaacctc tgccagcgaa agatgccrct cagtattagc gtggccttga ccttcccatc    300
tgccatgatg gcctcctatt acctgctgct gcagacctac gtactccgcc tggaagccat    360
catgaatggc atcttgctct tcttctgtgg sttttcttca gcacagacat ttgggcaagc    420
aactcagcat aaggccagtg ggtaccatct tctaaaccag gaccatcagc ccaagagact    480
cttntacact tcaagtatag ggaggggcaa nggtattccc atnctggccc tttttaagaa    540
cagtcccctg ntgaa                                                     555

<210> 1073
<211> 519
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (463)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (467)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (472)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (491)
<223> n equals a,t,g, or c

<400> 1073
gcagagcatg agattattct tttacatgat tacataatat tttattgtga gagcataact     60
ttattgaatt tatttataaa cactagtggc gagcatccat ytttcagctt ttcasaatta    120
aaaacaacac tgtgatgagc catccttata yatggattct ttctggaata agaaataaat    180
ggactgaaaa attagaatgt acaattctag aggtcccacg ttgtcaaatt atgttsaraa    240
atgtgcaccr cgaaaaagtc taaaagttca gccaagattc acatgggtca tttctgggca    300
aaaggaccag gcatgrtttt gktgktcttc ctattcttct gtcctcctca gcttttctat    360
tctaagtgtg tccttcggta tgctgatgca agttggcaat tttacattgc caagaatata    420
tggtttaatc cacgcaagtg tcgctctgac gatgctctct ttncagntcc tnctgnacca    480
cacttgctct natcatctgc tacaggggga agggacctg                           519

<210> 1074
<211> 1058
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (645)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (647)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1036)
<223> n equals a,t,g, or c

<400> 1074
tctcctgtac gccctagact aggggccgcc atctccatgg ccacggccgt gagccggccc     60
tgcgccggca ggtcgcggga catactgtgg cgcgttttgg gctggaggat asttgcaagt    120
attgtttggt cagtgctatt tctacccatc tgcaccacag tatttataat tttcagcakg    180
attgatttgt ttcatcctat acagtggctg tctgattctt tcagtgacct gtatagttcc    240
tatgtaatct tttacttcct gctgctgtca gtggtaataa taataataag tattttcaat    300
gtggagttct atgcagttgt gccttctatt ccttgctcca gactagctct gatagggaag    360
atcattcatc ctcagcaact catgcactca tttattcatg ctgcaatggg aatggtgatg    420
gcctggtgtg ctgcagtgat aacccagggc cagtacagct ttcttgtggt tccctgcact    480
ggtactaaca gctttggtag ccctgctgcg caaacctgct taaatgaata tcatcttttt    540
ttcctactgc tggagcattt atgggctata gctatagcct cctgtatttt ggtacaacat    600
gaactatctc catttcccat catacagcaa tacaagttct tgcgntntag gagatctctg    660
ctcttattag ttaaacacag ttgtgtggaa tcactgttcc tggttagaaa tttctgcatt    720
ttatattatt ttcttggcta tattcccaaa gcttggatta gcactgctat gaaccttcac    780
atagatsagc aggttcatag gccacttgac acagtgagtg gcctccttaa atctctcgtt    840
accctaccat gccctggctg gtgtggtgtc tttctcctga cgacttggta tgtctcatgg    900
atactcttca aaatctatgc cacagaggct catgtgtttt cctggttcaa accaccattt    960
ggcaagaaag gggtcagatg agtgccttcc caaaaagtgg ttaaaataag caatcctccc   1020
ccccaatcat aaagtnttta ggcccttgca gggaacct                           1058

<210> 1075
<211> 1505
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (372)
<223> n equals a,t,g, or c

<400> 1075
gatcctggca ganagtttgt tccggatggg ccccacctgc acctctacca tgagaaccac     60
tggataaagt taatgaattg gcagcacagc accatgtacc tattctttgc agtctmagga    120
attgttgaca tgctcaccta tctggtcagc cacgttccct tgggggtgga cagactggtt    180
atggctgtgg cagtattcat ggaaggtttc ctcttctact accacgtcca caaccggcct    240
ccgctggacc agcacatcca ctcactcctg ctgtatgctc tgttcggagg gtgtgttagt    300
atctccctag aggtgatctt ccgggaccac attgtgctgg aacttttccg aaccagtctc    360
atcattcttc angggaacct ggttctggca gattgggttt gtgctgttcc caccttttgg    420
aacacccgaa tgggaccaga aggatgatgc caacctcatg ttcatcacca tgtgcttctg    480
ctggcactac ctggctgccc tcagcattgt ggccgtcaac tattctcttg tttactgcct    540
tttgactcgg atgaagagac acggaagggg agaaatcatt ggaattcaga agctgaattc    600
agatgacact taccagaccg ccctcttgag tggctcagat gaggaatgag ccgagatgcg    660
gagggcgcag atgtcccact gcacagctgg aatgaatgga gttcatcccc tccacctgaa    720
tgcctgctgt ggtctgatct taagggtcta tatatttgca cctcctcatt caacacaggg    780
ctggaggttc tacaacagga aatcaggcct acagcatcct gtgtatcttg cagttgggat    840
ttttaaacat actataaagt ctgtgttggt atagtaccct tcataaggaa aaatgaagta    900
atgcctataa gtagcaggcc tttgtgcctc agtgtsaaga gaaatcaaga gatgctaaaa    960
gctttacaat ggaagtggcc tcatggatga atccggggta tgagcccagg agaacgtgct   1020
gcttttggta acttatccct ttttctctta agaaagcagg tactttctta ttagaaatat   1080
gttagaatgt gtaagcaaac gacagtgcct ttagaattac aattctaact tacatatttt   1140
ttgaaagtaa aataattcac aagctttggt attttaaaat tattgttaaa catatcataa   1200
ctaatcatac cagggtactg caataccact gtttataagt gacaaaatta ggccaaaggt   1260
gatttttttt taaatcasga agctggttac tggctctact gagagttgga gccctgatgt   1320
tctgattctt caaagtcmcc ctaaaagaag atctgacagg aaagctgtat aatgagatag   1380
aaaaacgtca ggtatggaag gctttcagtt ttaatatggc tgaaagcaaa ggataacgaa   1440
ttcagaatta gtaatgtaaa atcttgatac cctaatcttg cttctggatc tgttcttttt   1500
ttaaa                                                               1505

<210> 1076
<211> 951
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (206)
<223> n equals a,t,g, or c

<400> 1076
gtgggcatta gaagattccg tgcttgtggt gaaggcgagg cagccaaagc ctttctttgc     60
tgccggaaat acatttgaga tgacttgcaa agtatcttcc aagaatatta agtcgccacg    120
ctactctgtt ctcatcatgg ctgagaagcc tgtcggcgac ctctccagtc ccaatgaaac    180
gaagtacatc atctctctgg accaangatt tctgtggtga arctkgagaa ttggacagat    240
gcatyacggg tggatggcgt tgttttagaa aaagtgcagg aggatgagtt ccgctatcga    300
atgtaccaga ctcaggtctc agacgcaggg ctgtaccgct gcatggtgac agcctggtct    360
cctgtcaggg gcagcctttg gcgagaagca gcaaccagtc tctccaatcc tattgagata    420
gacttccaaa cctcaggtcc tatatttaat gcttctgtgc attcagacac accatcagta    480
attcggggag atctgatcaa attgttctgt atcatcactg tcgagggagc agcactggat    540
ccagatgaca tggcctttga tgtgtcctgg tttgcggtgc actcttttgg cctggacaag    600
gctcctgtgc tcctgtcttc cctggatcgg aarggcatcg tgaccacctc ccggagggac    660
tggaagagcg acctcagcct ggagcgcgtg agtgtgctgg aattcttgct gcaagtgcat    720
ggctccgagg accaggactt tggcaactac tactgttccg tgactccatg ggtgaagtca    780
csaacaggtt cctggcagaa ggaggcagag atccactcca agcccgtttt tataactgtg    840
aagatggatg tgctgaacgc cttcaagtat cccttgctga tcggcgtcgg tctgtccacg    900
gtcatcgggc tcctgtcctg tctcatcggg tactgcagct cccactggtg t             951

<210> 1077
<211> 1214
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (794)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1214)
<223> n equals a,t,g, or c

<400> 1077
ggcacgarga gacagcagcc catcccctca gcccacaccc ctgcgccctg tgggcaccga     60
caccacagaa gccaatgttt ggagatttgc acaacctccc gttcccccac atggagaagg    120
gaagtaagtt gaggcagccg tgggatggtg gtaggttccc tcttagtctt gctgctgttg    180
ctggaattcc aaagtgacct tagaaaccac gtgggggaag gcagtgctca ctacttagaa    240
gggttgcttc tragccgcct ggtcccccaa gagcacaaca ggcctcctcc ctctgaccac    300
agggtcatgc ctcctccctc tgaccacagg gtcatgcctc ctccctctga ccacagggtc    360
atgccagcct ccatttgcgc tgcgggagaa aagcccatct ctagcacacc ttgaccccag    420
gaaccgggtt cccgtatgga actgggaaga aaccgcccct gtgccagctc ccgcgggccc    480
tcctcgttcc ctcccagcct ccatggccgc cctctagagc ctccctgctg tacggagctc    540
tgggctccac ctatttgcaa tgttactctg aagtttctgg tgctattttt gtgttgtaat    600
gtgaayacag gcttccttga tttttttttt ttaatggggg tattgggtgg gacagacggg    660
gtcagggagg ccccaccatg gcttgtcgag ggcacgggca cctgcatggc ggcgctctcc    720
ctgcctcccc tgccgggctg caagcctgag gtctgtgctg ccggacgggg atgctcaggg    780
ctggggctgc aganccgctg ccctggccag ggcaccctca tgcaccgacc caacccaggc    840
ctgggacgca cgtgtcctct cacagcgtcg tgcctgtgaa ggtgggtcaa agggtgagag    900
ggcttccttc tcacccttct ctccataagt atcttgaaga tccatggttt gttttgctct    960
attgtttagt ttttacttgg gtgcaatgtg tacgtcaaaa gtttttattt tgatatttga   1020
aagagaccaa atcaggccca gaccgcctct ctggaaggtg ttgtaggcca ttcaaaacgc   1080
ctccggagtg tcgcaaacca agtgcggagg ggccctgagg ttgtactgta aacatcatag   1140
tgacttgtct tttcaaatat attcccacta ttttcgcaga aaaaaaaaaa aaaaaaaaaa   1200
acttcgaggg gggn                                                     1214

<210> 1078
<211> 652
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (502)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (522)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (525)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (560)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (599)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (630)
<223> n equals a,t,g, or c

<400> 1078
agacaggtga gcgacgaact tctgagacag cagttgtgtc cctgtggctt tggtgcgcct     60
gtgtgcactt tctccctcca cctggagcat gggctaacac cggaggaaag gaaaagacag    120
agtcagacag ggagcctggg gaggggccat ggtgccaatg cacttactgg ggagactgga    180
gaagccgctt ctcctcctgt gctgcgcctc cttcctactg gggctggctt tgctgggcat    240
aaagacggac atcacccccg ttgcttattt ctttctcaca ttgggtggct tcttcttgtt    300
tgcctatctc ctggtccggt ttctggaatg ggggcttcgg tcccagctcc aatcaatgca    360
gactkagagc ccagggycct caggcaatgc acgggacaat gaagcctttg aagtgccagt    420
ctatgaagag gccgtggtgg gactagaatc ccagtgccgc cccaagagtt ggaccaacca    480
cccccctaca gcaactggtg gngatacccc cagcaccctg anganggaac aacctagccc    540
attccagaag gggtccaggn agaagccaaa actgggaaca gaggccgaat gggccttana    600
agggggtccc atgggcccca ggaagggaan cccctgggaa gaacttccaa at            652

<210> 1079
<211> 1273
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (928)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1079)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1182)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1227)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1269)
<223> n equals a,t,g, or c

<400> 1079
tgagcaaccc tctttggcca ccagctccaa tcagactagc atgcaggatg aacaaccaag     60
tgattcattc caaggacagg cagcccagtc tggtgtttgg aatgacgaca gattgttagg    120
gcctagtcaa aattttgaag ctgagtcaat tcaagataat gcgcatatgg cagagggcac    180
aggtttctat ccctcagaac ccatgctctg tagtgaatcg gtggaagggc aagtgccaca    240
ttcattagag accttgtatc aatcagctga ctgttctgat gccaatgatg ccttgatagt    300
gttgatacat cttctcatgt tggagtcagg ttacatacct cagggcaccg aagccaaagc    360
actgtccatg ccggagaagt ggaagttgag cggggtgtat aagctgcagt acatgcatcc    420
tctctgcgag ggcagctccg ctactctcac ctgtgtgcct ttgggaaacc tgattgttgt    480
aaatgctaca ctaaaaatca acaatgagat tagaagtgtg aaaagattgc agctgctacc    540
agaatctttt atttgcaaag agaaactagg ggaaaatgta gccaacatat acaaagatct    600
tcagaaactc tctcgcctct ttaaagacca gctggtgtat cctcttytgg cttttacccg    660
acaagcactg aacctaccag atgtatttgg gttggtcgtc ctcccattgg aactgaaact    720
acggatcttc cgacttctgg atgttcgttc cgtcttgtct ttgtctgcgg tttgtcgtga    780
cctctttact gcttcaaatg acccactcct gtggaggttt ttatatctgc gtgattttcg    840
agacaatact gtcagagttc aagacacaga ttggaaagaa ctgtacagga agaggcacat    900
acaaagaaaa gaatccccga aagggcgngt ttgtgatgct cctgccatcg tcaactcaca    960
ccattccatt ctatcccaac cccttgcacc ctaggccatt tcctagstcc cgccttcctc   1020
caggaattat cgggggtgaa tatgaccaaa gaccaacact tccctatgtt ggagacccna   1080
tcagttcayt cattcctggt cctggggaga cgsccagcag kttcctccay tgagaccacg   1140
ctttgatcag ttggccactt tcaggaccta accccatctt gncagggcga aggccgggcc   1200
caatgacaga attcccttta gacccancaa gggtcgggcc aacttatggg cccggttgca   1260
attcaaggng aat                                                      1273

<210> 1080
<211> 2025
<212> DNA
<213> Homo sapiens

<400> 1080
gcccgagagg cccggttcct ttaggccgcc tgcccgcctc cagctctcgg ggtcggctcc     60
aggaggcgcc ctcaggagag gggcgggcgc tctattccag agaccgagtg gcagggcggc    120
cactgtggcg gggctctttc cccgtttcgc ctcagctacc cctcagctcc ggtagtcgcc    180
agtccggggt cgtcgccgtt tggggcggga gctgctcggc cccgccgccg tccccgtcgc    240
cgcttccggg tccaggcccc tcgggccgcc tgccgccgtc atgaggctgc gggtgcggct    300
tctgaagcgg acctggccgc tggaggtgcc cgagacggag ccgacgctgg ggcatttgcg    360
ctcgcacctg aggcagtccc tgctgtgcac ctgggggtac agttctaata cccgatttac    420
aattacattg aactacaagg atcccctcac tggagatgaa gagaccttgg cttcatatgg    480
gattgtttct ggggacttga tatgtttgat tcttcaagat gacattccag cgcctaatat    540
accttcatcc acagattcag agcattcttc actccagaat aatgagcaac cctctttggc    600
caccagctcc aatcagacta gcatrcagga tgaacaacca agtgattcat tccaaggaca    660
ggcagcccag tctggtgttt ggaatgacga cagtatgtta gggcctagtc aaaattttga    720
agctgagtca attcaagata atgcgcatat ggcagagggc acaggtttct atccctcaga    780
acccatgctc tgtagtgaat cggtggaagg gcaagtgcca cattcattag agaccttgta    840
tcaatcagct gactgttctg atgccaatga tgccttgata gtgttgatac atcttctcat    900
gttggagtca ggttacatac ctcagggcac cgaagccaaa gcactgtcca tgccggagaa    960
gtggaagttg agcggggtgt ataagctgca gtacatgcat cctctctgcg agggcagctc   1020
cgctactctc acctgtgtgc ctttgggaaa cctgattgtt gtaaatgcac tgaacctacc   1080
agatgtattt gggttggtcg tcctcccatt ggaactgaaa ctacggatct tccgacttct   1140
ggatgttcgt tccgtcttgt ctttgtctgc ggtttgtcgt gacctcttta ctgcttcaaa   1200
tgacccactc ctgtggaggt ttttatatct gcgtgatttt cgagacaata ctgtcagagt   1260
tcaagacaca gattggaaag aactgtacag gaagaggcac atacaaagaa aagaatcccc   1320
gaaagggcgg tttgtgatgc tcctgccatc gtcaactcac accattccat tctatcccaa   1380
ccccttgcac cctaggccat ttcctagctc ccgccttcct ccaggaatta tcgggggtga   1440
atatgaccaa agaccaacac ttccctatgt tggagaccca atcagttcac tcattcctgg   1500
tcctggggag acgcccagcc agtttcctcc actgagacca cgctttgatc cagttggccc   1560
acttccagga cctaacccca tcttgccagg gcgaggcggc cccaatgaca gatttccctt   1620
tagacccagc aggggtcggc caactgatgg ccggctgtca ttcatgtgat tgatttgtaa   1680
tttcatttct ggagctccat ttgtttttgt ttctaaacta cagatgtcaa ctccttgggg   1740
tgctgatctc gagtgttatt ttctgattgt ggtgttgaga gttgcactcc cagaaacctt   1800
ttaagagata catttatagc cctaggggtg gtatgaccca aaggttcctc tgtgacaagg   1860
ttggccttgg gaatagttgg ctgccaatct ccctgctctt ggttctcctc tagattgaag   1920
tttgttttct gatgctgttc ttaccagatt aaaaaaaagt gtaaattaaa aaaaaaaaaa   1980
aaaaaactyg aggggggccc sggacccaat tsccctatag ggggc                   2025

<210> 1081
<211> 1587
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (130)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (132)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (195)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1581)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1583)
<223> n equals a,t,g, or c

<400> 1081
attaatgcag ctggcacgac aggtttcccg attggaaagc gggcagtgag cgcaacgcaa     60
ttaatgtgag ttagntcact cattaggcac cccaggcttt acactttatg cttccggctc    120
gtaatgttgn gnggaattgt gagcggataa caatttcaca caggaaacag ctatgaccat    180
gattacgcca agctngaaat taaccctcac taaagggaaa caaaagctgg agctcccacc    240
gcggtggcgg ccgctctaga actagtggat ccccccgggc tgcaggaatt cggcacgagg    300
gcgctgattg cggacacccc gtaccacctg tatccggcct atggctgggt gatgttcgtc    360
gctgtcttcc tctggctggt gacaatcgtc ctcttcaacc tctacctgtt tcagctgcac    420
atgaagttgt acatggttcc ctggccactg gtgttaatga tctttaacat cagcgccacc    480
gttctctaca tcaccgcctt catcgcctgc tctgcggcag ttgacctgac atccctgagg    540
ggcacccggc cttataacca gcgcgcggct gcctcgttct ttgcgtgttt ggtgatgatc    600
gcctatggag tgagtgcctt cttcagctac caggcctggc gaggagtagg cagcaatgcg    660
gccaccagtc agatggctgg cggctatgcc taaaccacct gtgccacggc cccctctggg    720
gctgaagccg ccgctgggtc acagagcagg gtcaccctgc aagcctgaag ctggggagcc    780
ctgcgtggag tcagcccaac agggactgca tttgctcctc tctgcccgtc agayataagc    840
tctcacagcg ctaaggaagc aggcccaggc tggcaggcat ctcggcttgc aggaggccaa    900
ctgctgagac ctcttctcca tcccccttat tcagtggaag atgacggggg atctgaggct    960
gtgtctctgc cttgtcttta gaggacttca gcgtccaaga ctggggccca cccttctcac   1020
cagcactaaa tgcactaaca aggactccag acctgcagcc ccagacccgc cgtagtataa   1080
gcctaacaag caacacgtag caccttagtc tttgttccag gagagctgag caagctggtg   1140
aaaccactgc tccttccttt aaacaccgtt tcaaccaacc tctccctgga gccaacctgt   1200
aaaaagtggg ttgattgctg acagcatggt cttccctccc tgcatttcag acataccagt   1260
tactgaaagc aaatcagttt taagtgattt ctcagtgctg aaaagcctgt ccaggtttcc   1320
ttccctttcc caagcctctc tctgtaatac tccctttggg cgaagctaac atcggtgcct   1380
ccccgacctt gctgactagg cacatgggac gcaaaggagg gagggaagca aggccttgcc   1440
tggcgagttg tcatgtggtt ggtggtgact gttttatttt ttttaataaa aataaagatg   1500
agagaaatta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aactcgaggg   1560
ggggcccgta cccaatcgcc ngngatg                                       1587

<210> 1082
<211> 1393
<212> DNA
<213> Homo sapiens

<400> 1082
aattcggcac agcgggagtt cctgcacgct gcagagaccc cggtgcccag cgtcggggag     60
tacctcaaga aggagattgg ccagcacgtg gccggctgga cagaggatga ggaccaggaa    120
gctgaagctg gccgtcctga actccttctt caacctggaa tgctgtgtga gcggcaccca    180
cagcatggac ctggtggccc tggcaccctt tggggagtat accgtgctgc cggggctgga    240
ctgcaccttt tctaagggct atcaaggact cacaaactgc atgatggccg ccctgccgga    300
ggacactgta gtttttgaga agcctgtgaa gaccatccac tggaacgggt ccttccagga    360
ggcagccttt cccggggaga cctttccagt gtcggtagag tgtgaggatg gagaccggtt    420
cccggcgcac catgtcatcg tcaccgtgcc cttaggtttt cttagggaac atttggacac    480
cttctttgac cctcccctgc cggctgagaa ggcagaagca atcaggaaga taggctttgg    540
gaccaacaac aaaatcttcc tggagtttga ggagcccttc tgggagccag actgccagct    600
gatccagctg gtgtgggagg acacgtcgcc cctggaggat gctgcccctg agctacagga    660
cgcctggttc cggaagctca ttggctttgt ggtcctgcct gcctttgcgt ctgtccacgt    720
tctctgtggg ttcattgccg gacttgagtc tgagttcatg gagactctgt cggatgaaga    780
agtacttctg tgtctcaccc aagtgctccg gagagtgaca ggaaacccac ggctccccgc    840
gcccaagagc gtcctgcggt ctcgctggca cagcgccccg tacactaggg ggtcctacag    900
ctacgtggcc gtgggcagta ctgggggcga cctggacctg ctggctcagc ccctccctgc    960
agacggcgcc ggcgcccagc tccagatcct gtttgcgggg gaagccacac atcgcacgtt   1020
ttactccacg acgcacgggg ctctgctgtc gggatggarg gaggccgacc gcctcctcag   1080
tctgtgggcc ccgcaggtgc agcagcccag gccgaggctc tagctgggcc cagcctactc   1140
tgttccaccc gtgtcggggg taggctggga ccgtcatttc ttctgacaga tttcagtctg   1200
gcttgaaatt tggggatgtt aatgagggtc ctctggtttt tggtaaccag ggccaccttc   1260
tcagttcttg tgtctgttat tggagtctgg ccagggttga cttgagctga gacaccagat   1320
gctcacggag atgctggaca cataaagcaa gttacagcca caaaaaaaaa aaaaaaaaaa   1380
aaaaaaatta ctg                                                      1393

<210> 1083
<211> 595
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (551)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (575)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (587)
<223> n equals a,t,g, or c

<400> 1083
ctgacctgca tgctgttttt ccttgtttcg gtcatctaca agaagttcca acttggctgt     60
gctataggcc acaatgaaac agcaatggag agtgaagctc tcgtgggact ccccagccaa    120
ggactcaaca gcagctgtga ggcccagatg ttcacagttg actcacagat gtcctacaca    180
gtgcccatta tggcttttgc ttttgtctgc caccctgagg tgctgcccat ctatacggag    240
ctctgccggc cctccaagcg caggatgcag gccgtggcca acgtgtccat tggggccatg    300
ttctgcatgt atgggctcac agcaaccttt ggatacctca ccttctacag cagtgtgaag    360
gcggagatgc tgcacatgta cagccagaag gacccgctca tcctctgtgt gcgcctggcc    420
gtgctgctcg cggtgaccct cactgtgcca gtcgtgctgt tccctatccg scgggccctg    480
cagcagctgc ttttcccagg caaggccttc agctggccac gacatgtggc catagctctg    540
atcctgcttg ntttggtcaa tgtccttgca tctgngngcc aaccatncgg gatat         595

<210> 1084
<211> 1410
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (648)
<223> n equals a,t,g, or c

<400> 1084
gggacagccg ggatgaactg ctggccagca tgatggcggg cgtgaagtgc cgcctggaca     60
gtagcctgcc ccccgtgcga cgcctgggca tgatcgtggc agaggtcgtt agtgcccgga    120
tccaccccga ggggcctccc ctgaaattcc agtacgaaga ggatgaactg agcctcgagc    180
tgctggcctt ggcctccccc cagcctgcgg gtgacggcgc ctcggaggcg ggcacgtccc    240
tcgttccagc cacggcagag ccccctgcag agacccccgc agagatcgtg gatggcggcg    300
tcccccaagc acagctggcg ggctctgact cggacctgga cagcgatgat gagtttgtcc    360
cctacgacat gtcgggggac agararctga agagcagcaa ggctcctgcc tacgtccggg    420
actgcgtgga agccctgacc acgtctgagg acatagagcg ctgggaggca gccctgcggg    480
ccgcttgagg gcctggtcta caggagcccc acagccactc gggaggtgag cgtggagctg    540
gccaaggtgc ttctgcatct ggaggagaag acctgtgtgg tgggatttgc agggctgcgc    600
agagagccct ggtggccgtc acggtcacag acccggcccc ggtggccnac ttatctgacc    660
tcacagttct atgccctcaa ctacagcctc cggcagcgca tggacatcct ggatgtgctg    720
actctggctg cccaggagct gtctaggcct gggtgcctcg ggaggactcc ccaacctggc    780
tccccaagtc ccaacacccc gtgcctgcca gaggcagccg tctctcagcc tggcagtgcc    840
gtggcgtctg actggcgggt ggtggtggag gagcggatca gaagcaagac ccagcggctc    900
tccaagggtg gcccgaggca gggcccggca ggcagcccca gcagattcaa ctccgtggcc    960
ggccacttct tcttccccct ccttcagcgc tttgacaggc ctctggtgac cttcgacctc   1020
ttgggagaag accagctggt tctcggaagg ctggcgcaca ccttaggggc cctgatgtgc   1080
ctggctgtta acaccacggt ggctgtggcc atgggcaagg ccctgctgga attcgtgtgg   1140
gcccttcgct tccacatcga tgcctacgtg cgccaggggc tgttgtcggc cgtctcctcc   1200
gtcctgctca gcctgcctgc tgcgcgcctg ctggaggacc tgatggacga gctgctggaa   1260
gcccggtcct ggctggcgga cgtggctgag aaagacccgg acgaggactg magacgctkg   1320
cactgaggcc ctgctgytyt gagagactca agaacaggtt cttccacccg tctcctagtc   1380
ctggaggctc caggacaccc cgccacagca                                    1410

<210> 1085
<211> 538
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (213)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (439)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (505)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (509)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (520)
<223> n equals a,t,g, or c

<400> 1085
gcttctgggt ggcctaccgc aatgaggacc gctgggcgtg gctcctgcag gacacactgg     60
gcatttccta ctgcctgttc gtcctgcacc gtgtgcggct gcccactctc aagaactgct    120
cctccttcct gctggccctg ctggcctttg atgtcttctt tgtcttcgtc acccccttct    180
tcaccaaaac cgggtgagag catcatggcg cangttgcct tgggccctgc agagtcttca    240
agccatgaga ggctgcccat ggtactcaaa gtgccccggc taagagtctc cgscttgacc    300
ctgtgcagcc agcccttctc catccttggc ttcggtgaca ttgtggtccc cggcttcctg    360
gttgcttact gttgccgctt tgatgtgcaa gtctgctccc gtcagatcta cttcgtggcc    420
tgaccgkggc ctatgctgng ggcctgtggt cacattcatg gcatggcctc atgcagatgg    480
ccaacctgcc ttggttacct agggncaana cctgttacan cctgctgggt gctgcgca      538

<210> 1086
<211> 1014
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (955)
<223> n equals a,t,g, or c

<400> 1086
gaacgccctc tcgaaattac ccctcactaa agggaacaaa agctggagct ccaccgcggt     60
ggcggccgct ctagaactag tggatccccc gggctgcagg catgggatgc ggcgattttc    120
cacttgatga cccacgcgtt ctttaaagcg ctgctgttcc tggcatccgg ttccgtcatt    180
ctggcctgcc atcacgaaca gaacatcttc aagatgggcg gtctgcgtaa atctattccg    240
ctggtttatc tctgcttcct ggtgggcggc gcagcactgt cggcactacc gctggtcact    300
gcgggcttct tcagtaagga tgagatcctc gcgggtgcga tggcgaatgg tcatatcaat    360
ctgatggtgg caggtctggy cggtgcgttt atgacctcgc tctacacctt ccgtatgatt    420
ttcatcgtct tccacggaaa agamcaaatt cacgctcacg ccgtgaaagg ggtwactcac    480
agcctgccgc tgattgtgct gctgatcctt tccaccttcg ttggcgcact gattgtaccg    540
ccgctgcarg gcgtgcttcc gcaaacgacg gaactggcgc acggcagcat gttkaccctg    600
gaaattacct ctggcgtggt cgcggtggtc ggcattctgc tggcagcctg gctgtggctg    660
ggtaaacgta ctctggtgac ctccatcgcc aacagtgcgc cgggccgtct gctgggcacc    720
tggtggtaca acgcctgggg atttgactgg ctgtatgaca aagtgttcgt caagccgttc    780
ctgggtattg cctggttgct gaaacgcgat ccgctgaact caatgatgaw catcccggct    840
gtcctttccc gctttgcagg taaaggtctg ctgttaagtg agaacggcta tctgcgctgg    900
tatgtggcat ccatgagcat cggtgcggtc gtggtgctgg cactgttgat ggtantgcgt    960
tgagttaagg attgtgggat tgcccctggg catataagaa cgtggggggg cccg         1014

<210> 1087
<211> 821
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (39)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (53)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (59)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (68)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (111)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (121)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (810)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (813)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (818)
<223> n equals a,t,g, or c

<400> 1087
atgcttccgg gctcgtatgt tgtgtgaaat tgtnancgna taccattttc acncagaanc     60
agctatgncc atgattccgc caagctcgaa attacccctc actaaaggga ncaaaagctg    120
nagctccacc gcggtggcgs ccgctctaga actagtggat cccccgggcc gcaaattctt    180
ggcgttgctg gcatggatac cagcgccgtc ttcgtcacta cctgtctgat cgctgcattc    240
ggcagtatta tgatgggact gtttgctaac ctgccagttg cactggcacc cgctatgggc    300
ctgaatgcgt tcttcgcttt tgtcgttgta caggcgatgg gcttgccgtg gcaggtcggg    360
atgggcgcaa tcttctgggg cgcgataggt ctgctgttac tgacgatttt ccgcgttcgc    420
tactggatga tagccaacat tccggtgagt ctgcgtgtgg gtattaccag cggtatcggt    480
ctgttcattg gcatgatggg gctgaaaaac gcaggtgtga ttgtcgctaa cccggaaacg    540
ctggtgagca tcggtaatct gacttctcac agcgtacttc tgggtatcct cggcttcttc    600
atcattgcta ttctggcctc gcgcaacatt cacgcagcgg tgctggtttc tatcgtggtg    660
acgacgctgc tgggctggat gctgggtgat gtgcactaca atggcatcgt ttctgcgccg    720
ccgagcgtaa tgacagttgt gggtcatgta gatttagccg ggtcgtttaa cctcgggctg    780
gcagaagggc ccggaagcat tccagtaggn acnccgtnaa g                        821

<210> 1088
<211> 1053
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1047)
<223> n equals a,t,g, or c

<400> 1088
atcctgaggc tgcccgcctc cttcctcagc ccctccctgg tcaggcgctc ctggtgggtg     60
gsgggggtag tccaggcttg tcttgcaact gtatgttctc ttcagacccc tccctggcga    120
tgccagattc actgggctgg cagattctgc ccccaaacct gtccaaccag ttgtttgaga    180
ggagggggta gctgggaggg gcagcaggag atgccaggaa cagcttcccc tagcacagca    240
cagactacag acaggggagc ctctggggct gcagacactg cagacggacg gacagacaga    300
tggacaacag ctggaggctt ggcccggcca tagggctctc tgcgggacag tcccagctgc    360
tagtgtcgct gttgctgcta ctgacccgtg tccagcctgg gacagacgtg gctgccccag    420
agcacatcag ctatgtgccc cagctctcaa acgacacctt ggcggggagg ctcaccctgt    480
ccaccttcac gctggagcag cctctaggcc agttcagcag ccacaacatc tctgacttgg    540
ataccatctg gctggtggtg gccctcagca acgccaccca gagcttcacg gccccacgga    600
caaaccagga catccctgct cctgccaact tctcccagag gggctactat ctcacactga    660
gggccaaccg ggtgctgtac cagaccagag gccagctcca tgtcctccgc gtcggcaatg    720
atacccactg ccaaccaaca aaaattggct gcaaccatcc cctaccagga cccggcccct    780
acagggtgaa gttcctggtg atgaatgacg aaggacccgt ggctgaaacc aagtggtcca    840
gcgacactcg cctgcagcaa gcccaggcay ttcgggctgt ccccggcccc cagagcccgg    900
gcacgtggtt catcatcgcc atcctgtcta tcctcctggc cgtctyctwm aggtctctgg    960
ctgtgctcat atacactgga ctgcttcttc caaagttctt ttggggcttt ggcatggaca   1020
gaagacagca acagaagcat gtagatntat ggt                                1053

<210> 1089
<211> 1529
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1514)
<223> n equals a,t,g, or c

<400> 1089
atgtctggaa catcatgcct actttggagg ggtgggtggt tctgtggcag cagaaagctg     60
cagaggcact taccccaacc caggnggcac aaggggaaac ggagcctact gaacaggcac    120
ctgaygcctt ggagcaagca gcagacactt ctagacggaa cgcagaaact ccagaggcca    180
ccacacagca ggaaacggac actgatctcc cagaggcccc tccacccccc ctagaacctg    240
ctgtcatcgc acgccctggc tgtgtaaacc tgtccctcca tgggattgtg gaggatcgga    300
ggccaaagga aaggatctct tttgaggtga tggtgctggc cgagctgttt ctggagatgc    360
tccagaggga ttttggctat agagtttata agatgctact gagccttcct gaaaaggtcg    420
tgtccccacc tgaacctgag aaggaggagg cggccaagga agaagccacc aaggaggaag    480
aagccatcaa agaggaggtg gtcaaggagc ccaaggatga ggcacagaat gagggcccgg    540
ctacagagtc agaggccccg ctgaaggagg atgggctttt gcccaaacca ctctcttctg    600
ggggagagga agaagaaaaa ccccggggcg aggcttctga ggacctgtgt gagatggccc    660
tggacccaga actgttgctt ctgagggatg atggagagga ggagtttgca ggagcaaagc    720
tggaggattc ggaggtccgg tccgttgcct caaaccagtc agagatggag ttctcttcac    780
ttcaggacat gcccaaggag ctggatccct ctgctgtgct ccccttagac tgtctgcttg    840
cttttgtgtt ctttgatgcc aactggtgtg gctacttgca ccggcgagac ttagagagga    900
tcctccttac ccttgggatc cggctcagtg cagagcaggc caagcagctg gtcagcaggg    960
tggtgaccca gaacatctgc cagtaccgga gccttcagta cagccgccag gagggcctgg   1020
atggtggcct tcccgaggag gtgctcttcg gaaacctgga cctgctgccc cctcctggga   1080
aaagcacgaa gccaggtgct gcccccacag aacacaaagc cttggtgtcc cacaatggca   1140
gcctgattaa cgtggggagc ctgctgcagc gcgcggagca gcaggacagc ggccggctct   1200
acctagagaa caagatccac acactggagc tgaagctgga ggagagccat aaccgtttct   1260
cagccactga agtaaccaat aagacgctgg cggcagagat gcaggagctg cgagtccggc   1320
tggcggaggc cgaggagacc gcccggacgg cggagcgaca gaagagccag ctccagcggc   1380
tgctgcagga gctccgcagg cgtctgaccc ccctgcagct ggagatccag cgggtggtgg   1440
aaaakgtaag stgggtggas aggagrcaac acaatnacct gacgaatgca ttgtagcaac   1500
gtggccgcaa ttanctcgta caaacacag                                     1529

<210> 1090
<211> 394
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (394)
<223> n equals a,t,g, or c

<400> 1090
gaattcggca cgagatgtgg tctccagtgg ccatgctttg ctgcgccagg cctgtgacat     60
ctgtgccatt gccatgagcc tggtggctta tgtgatcaac agcctggtca acatctgcct    120
catcggcact cagaacctct tttccctggt gctggccctg tgggatgcag tgaccgggcc    180
tctgtggagg atgacagacg tagtggctgc cttcctagcc cacatttcca gcagtgctgt    240
ggccatggcc atcctccttt ggacaccctg ccaactagcc ctggagctgc tggcctcagc    300
tgcccgcctc ctggccagct ttgtgcttgt caatctcact ggcttggtgt tgctagcttg    360
tgtgctggca gtramggtac trtrwwgcat ccan                                394

<210> 1091
<211> 789
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (188)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (496)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (745)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (786)
<223> n equals a,t,g, or c

<400> 1091
tactgactag tcttctgcac ttgggccgcg gagtcttgct ttcattgctg gccttgatcg     60
aagccgtggt ccggttcaca tgtgggggct tgcaggcctt gtgtactctg ctgtatagct    120
gctgctctgg cctagagagc ctaaagctcc tggggcacct ggcctctcat ggggcactgc    180
ggacaggnag atactgcacc ggggcgtcct caatgtggtc tccagtggcc atgctttgct    240
gcgccaggcc tgtgacatct gtgccattgc catgagcctg gtggcttatg tgatcaacag    300
cctggtcaac atctgcctca tcggcactca gaacctcttt tccctggtgc tggccctgtg    360
ggatgcagtg accgggcctc tgtggaggat gacagacgta tggctgcctt cctagcccac    420
atttccagca gtgctgtggc catggccatc ctcctttgga caccctgcca actagccctg    480
gagctgctgg cctcanctgc ccgcctcctg gccagctttg tgcttgtcaa tctcactggc    540
ttggtgttgc tagcttgtgt gctggcagtg acggtgactg tgttgcatcc ggacttcacc    600
ctgaggctgg ctacccaggc actcagccag ctccatgccc ggccatccta ccaccgtctt    660
cgagaggatg tcatgcggct ctctcgccta gcactgggct cagaggcctg gcgccgagtc    720
tggagccgma tctgcagctg gcganttggc caaaccgggg aagggcactg gagctcccca    780
ggtgancta                                                            789

<210> 1092
<211> 2351
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (141)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (294)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (303)
<223> n equals a,t,g, or c

<400> 1092
attctacagc agaatatact tggaaaaact caagtttttc cacatacttg gaaaaactct     60
ctagcatttg tnggaattta gtgtaattaa gtgaaaccta cctagcaact gtagtaatta    120
aaagcgtggg gtgtgctttt ngttgagatc cgtgaatgtt tctgtaaaca caattttgat    180
tgtgttgcgc ttcttaaagg ttgtgatgac aacggtaatt ttaaccactt gaccgtatat    240
cgttttcatc cttgaagact gtcatatatt tccaagtgtc tttcctccct ggtnatttta    300
ggntaaagat cgaggtccgg aagccactag gagatttttt aattggtttt attggagcat    360
taacctggga gcgatcctgt cgttaggtgg cattgcctat attcagcaga acgtcagctt    420
tgtcactggt tatgcgatcc ccactgtctg cgtcggcctt gcttttgtgg ycttcctctg    480
tggccagagc gttttcatca ccaagcctcc tgatggcagt gccttcaccg acatgttcaa    540
gatactgacg tattcctgct gttcccagaa gcgaagtgga gagcgccaga gtaatggatg    600
cagacaacat atgttttaca gagtcttcat ttgaggattc cagaaatttc aaatattaca    660
accactcctc acacgctccc tgcagcctgg ctgaccatgt ttgatgctgt gctcatcctc    720
ctgctcatcc ctctgaagga caaactggtc gatcccattt tgagaagaca tggcctgctc    780
ccatcctccc tgaagaggat cgccgtgggc atgttctttg tcatgtgctc rgcctttgct    840
gcaggaattt tggagagtaa aaggctgaac cttgttaaag agaaaaccat taatcagacc    900
atcggcaacg tcgtctacca tgctgccgat ctgtcgctgt ggtggcaggt gccgcagtac    960
ttgctgattg ggatcagcga gatctttgca agtatcgcag gcctggaatt tgcatactca   1020
gctgccccca agtccatgca gagtgccata atgggcttgt tctttttctt ctctggcgtc   1080
gggtcgttcg tgggttctgg actgctggca ctggtgtcta tcaaagccat cggatggatg   1140
agcagtcaca cagactttgg taatattaac ggctgctatt tgaactatta ctttttcctt   1200
ctggctgcta ttcaaggagc taccctcctg cttttcctca ttatttctgt gaaatatgac   1260
catcatcgag accatcagcg atcaagagcc aatggcgtgc ccaccagcag gagggcctga   1320
ccttcctgag gccatgtgcg gtttctgagg ctgacatgtc agtaactgac tggggtgcac   1380
tgagaacagg caagacttta aattcccata aaatgtctga cttcactgaa acttgcatgt   1440
tgcctggatt gatttcttct ttccctctat ccaaaggagc ttggtaagtg ccttactgca   1500
gcgtgtctcc tggcacgctg ggccctccgg gaggagagct gcagatttcg agtatgtcgc   1560
ttgtcattca aggtctctgt gaatcctcta gctgggttcc cttttttaca gaaactcaca   1620
aatggagatt gcaaagtctt ggggaactcc acgtgttagt tggcatccca gtttcttaaa   1680
caaatagtat cacctgcttc ccatagccat atctcactgt aaaaaaaaaa attaataaac   1740
tgttacttat atttaagaaa gtgaggattt tttttttttt aaagataaaa gcatggtcag   1800
atgctgcaag gattttacat aaatgccata tttatggttt ccttcctgag aacaatcttg   1860
ctcttgccat gttctttgat ttaggctggt agtaaacaca tttcatctgc tgcttcaaaa   1920
agtacttact ttttaaacca tcaacattac ttttctttct taaggcaagg catgcataag   1980
agtcatttga gaccatgtgt cccatctcaa gccacagagc aactcacggg gtacttcaca   2040
ccttacctag tcagagtgct tatatatagc tttattttgg tacgattgag actaaagact   2100
gatcatggtt gtatgtaagg aaaacattct tttgaacaga aatagtgtaa ttaaaaataa   2160
ttgaaagtgt taaatgtgaa cttgagctgt ttgaccagtc acatttttgt attgttactg   2220
tacgtgtatc tggggcttct ccgtttgtta atactttttc tgtatttgtt gctgtatttt   2280
tggcataact ttattataaa aagcatctca aatgcgaaat mmaaaaaaaa aaaaaaaaaa   2340
ttggcggccg c                                                        2351

<210> 1093
<211> 1422
<212> DNA
<213> Homo sapiens

<400> 1093
ccgcctcctt gccgcccagc cggtccaggc ctctggcgaa catggcgctt gtcccctgcc     60
aggtgctgcg gatggcaatc ctgctgtctt actgctctat cctgtgtaac tacaaggcca    120
tcgaaatgcc ctcacaccag acctacggag ggagctggaa attcctgacg ttcattgatc    180
tggttatcca ggctgtcttt tttggcatct gtgtgctgac tgatctttcc agtcttctga    240
ctcgaggaag tgggaaccag gagcaagaga ggcagctcaa gaagctcatc tctctccggg    300
actggatgtt agctgtgttg gcctttcctg ttggggtttt tgttgtagca gtgttctgga    360
tcatttatgc ctatgacaga gagatgatat acccgaagct gctggataat tttatcccag    420
ggtggctgaa tcacggaatg cacacgacgg ttctgccctt tatattaatc gagatgagga    480
catcgcacca tcagtatccc agcaggagca gcggacttac cgccatatgt accttctctg    540
ttggctatat attatgggtg tgctgggtgc atcatgtaac tggcatgtgg gtgtaccctt    600
tcctggaaca cattggccca ggagccagaa tcatcttctt tgggtctaca accatcttaa    660
tgaacttcct gtacctgctg ggagaagttc tgaacaacta tatctgggat acacagaaaa    720
gtatggaaga agagaaagaa aagcctaaat tggaatgaga tccaagtcta aacgcaagag    780
ctagattgag ccgccattga agactccttc ccctcgggca ttggcagtgg gggagaaaag    840
gcttcaaagg aacttggtgg catcagcacc cccctccccc aatgaggaca ccttttatat    900
ataaatatgt ataaacatag aatacagttg tttccaaaag aactcaccct cactgtgtgt    960
taaagaattc ttcccaaagt cattactgat aataacattt tttccttttc tagttttaaa   1020
accagaattg gaccttggat ttttattttg gcaattgtaa ctccatctaa tcaagaaaga   1080
ataaaagttt attgcacttc tttttgagaa atatgttaaa gtcaaagggg catatataga   1140
gtaaggcttt tgtgtattta atcctaaagg tggctgtaat catgaaccta ggccaccatg   1200
gggacctgag agggaagggg acagatgttt ctcattgcat aatgtcacag ttgcctcaaa   1260
tgagcaccat ttgtaataat gatgtcaatt tcatgaaaag cctgagtgta ttgcatctct   1320
tgatttaatc atgtgaaact tttcctagat gcaaatgctg actaataaag acaaagccac   1380
cctgaaaaaa aaaaaaaaaa aaaaaaaaaa aagggcggcc gc                      1422

<210> 1094
<211> 1134
<212> DNA
<213> Homo sapiens

<400> 1094
gtggtgtctt tctccgctga gattttgtca cggacactat gtgaacccct tgtggcgtct     60
ctctggatga aactggggaa cacgggggcc atgagaaggt gtgtgaagct aacagtcgct    120
cttgagactg ctgaatgtga attcccccct cacctggatg tatatataga agacccacac    180
ttgcctccct cactaggact acttccagga gcccgggtcc acttcagcca gttggagaaa    240
agggtttcca gatctcacaa tgtttattgt tgyttccggt catccactta tgtgcaggtc    300
ctgagttttc cccctgagac caccatcagc gktcccctgc cccacatcta cctggctgaa    360
cttctgcagg gtggtcagtc cccattccag gccactgcct cttgcatatc gctctgtctt    420
cagccttcag ctcttctggg tgtgtgctta ttgtaccagc atctgccggc agtcttcagc    480
cagggttgac gagcccatga ccatgktcct ctggacactt tgkactarcc cctctgtcct    540
ccgtcctatt gtgctttctt ttgagctgga aaggaaaccg tcgaagatcg tcccattaga    600
acctcctcgg ctacagcgat tccagtgtgg agagctccct ttcctgactc acgtgaaccc    660
caggctccga ttgtcctgcc tttctatccg agagtcagag tactccagct ctctggggat    720
ccttgcttcc tcctgttaac tgaactgcaa ggatggcctg agagtccttc cttgctgaaa    780
acctgaaggc ctaggtcctg gctcctctcc ctacttgttc tgtgattgaa ccaaggactc    840
cagattcaca aactgctact ccactataat ttcccttctt tggtgttctg gtgccagcct    900
gccttggcaa aattgtggca acaggaaatc atggccctat taatatgtcc tctgattggg    960
acaaggcacc tgcattcaca ggcggccctg agcacctggg ttctgacttt gtcgcaggag   1020
ctgagggaac aaaagacttg ctcgctgtgg ggtgatggtg acaggcctat tgacctgcaa   1080
tgaagccctc tggtgtcatt tmaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa         1134

<210> 1095
<211> 1715
<212> DNA
<213> Homo sapiens

<400> 1095
ggcacagccc acacgccccc gccgcccgcg ccccgtccac ccgcgccccg ctcccgrgga     60
ctgggagaac aggatagcag caggagtcgg ggggccgccg aagatgggga acactacctc    120
gtgctgcgtg tcgtccagtc ccaagctccg gaggaatgcc cactcccggc tggagtccta    180
ccggccagac acggacctga gccgcgagga cacgggctgc aacctgcasa catcagcgac    240
cgggagaaca tagacgattt gaacatggaa ttcaatcctt cagatcatcc tcgggccagc    300
acaatattcc tcagtaaatc tcagacrgac gtgagagaaa aacgcaagag tctcttcatt    360
aaccatcatc ctccaggaca aatagcaagg aaatacagtt cctgctccac cattttccta    420
gatgatagca cagtcagtca accaaacctc aagtatacaa ttaaatgtgt cgctcttgca    480
atatattatc acatcaaaaa cagggaccca gatggaagga tgctcttaga tatttttgat    540
gaaaatcttc accctctttc gaaatccgaa gtgccaccag attatgacaa acacaaccca    600
gagcagaagc agatttaccg gttcgttcgg acactgttca gtgctgctca gctgacggct    660
gaatgtgcca tcgtcaccct ggtgtacctt gaaagacttt taacatacgc agagatagat    720
atctgtccgg ccaactggaa gcggattgtt ttaggggcga tcctgctggc ctccaaggtg    780
tgggatgacc aggctgtatg gaatgtggat tactgccaga tcctgaaaga catcacggtg    840
gaggacatga acgagctaga gcgacagttt cttgaattgc tgcagttcaa catcaatgtt    900
ccttccagtg tctatgccaa gtattatttt gatcttcgtt ctctggcaga agcgaacaac    960
ctgagctttc ccttggagcc cctgagcagg gagagggctc acaagcttga ggccatctct   1020
cgcctctgcg aggacaagta caaggaccta agaagatccg cgaggaagcg ctcagccagt   1080
gcagacaacc tgactctgcc ccggtggtcc ccagccatca tctcttaact acggaggccc   1140
gccggaggcc acaccatccc ttagtttctc ctttagtttg agaaaagaca gacttggggt   1200
gggtttgttt ttgttttttc tttccttttc tttttttacg catagctccg tcaagctgcc   1260
tggatgagcg cccatgcagc aaggcttgga ggaagcgtca gtgccctgga gatcccagct   1320
cgctctcccc actgtcagca acagcacttc cttcgtggag gaagtggact cgaatcctgg   1380
aggaggaaat aaagggaaag ggaagtcgtg gagaggcagg gaaaatggtt aagcagcccg   1440
gccctctgga gtccccatgg gggcggtagc tgaagttggc gagcgcagcg gtggatgcag   1500
agctggctgc acccagggct gggccagtgt gtcctgtaag acttcttgca ttccttctgc   1560
tgcttttttg ggatgggggt atttttgttc atttgttttt gccctgtttt gattttggtc   1620
ccacagagca ggggatgtag tttgtaccca ccatggcgca gacttccaaa taaatagtac   1680
tggtcatttc aaaaaaaaaa aaaaaaaaaa aaaaa                              1715

<210> 1096
<211> 981
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (446)
<223> n equals a,t,g, or c

<400> 1096
ggtcaacacc ttctcccaga gcgtcagcag cctgttcggc gaggacaacg tgcgcgccgc     60
tcagaagttc ttggccaggc tgactgagag atttgtgctg ggagtggata tgttcgtgga    120
gacactgtgg aaagtctgga ccgagctctt ggatgttctt ggacttgacg tctccaacct    180
gtcccagtat ttcagcccag cctcggtgtc cagcagcccg gcccgcgcgc tcctgctggt    240
cggcgtcgtc ctcctggcct actggttctt gtccctgacc ctgggcttca ctttcagcgt    300
cctgcacgtg gtgttcggcc gcttcttctg gatcgtgcgg gtcgtcctgt tttccatgtc    360
ctgcgtgtac atcctgcaca agtacgaggg cgagccggag aacgcggtgc tgccgctgtg    420
cttcgtggtg gccgtctact tcatgnaccg ggcccatggg cttctactgg cgaamagtcc    480
cagcggcccc agcaacccca gcaaccccag cgtggaggag aagctggagc acctggagaa    540
gcaggtcaga ctgctcaaca tccgtstcaa ccgggtgctc gagagcctgg accgctccaa    600
ggacaagtga aggtcagccg gccgggcggg tccacagtta ccagcacgct gtctcagaaa    660
acgaaaacgg aggaaaaaaa ccccaaaccc caaacaatct taataaacac gactgagcaa    720
gaaagtggcg ctgtgtargg ctatttccac ccacccggca gctcttagga cacattccca    780
gaagagcgga aagatcattg acgtggaact acacacgaag tgtaattagt gggggaaaaa    840
atatttttta aacaaaggat ataaccatat ttagttgtac agtaagagaa atttatctgt    900
gcatagagca taaagttaat tttttcaagc atttaaatac atcttttgta aggtttttta    960
ataaaggcag attgagtcaa g                                              981

<210> 1097
<211> 1474
<212> DNA
<213> Homo sapiens

<400> 1097
gacccacgcg tccgcgcaga accaggaaag taacggctac agacagtgag aaatagtttc     60
gctcgccggc tagaaaaact ctgtcggtac caaccccaga gcgttgagag cagcccacct    120
ccacgcttcc ttaacggaga ggtgcaggac tcagacttca ccagcccact cggtcccagc    180
cttgtacgca aagagacgtc aaggacgcgc tctcccgcgt ccaggcagcc ccagcttgct    240
ggcttgcctg cccgcctgcg tgcagcactc ggccggcgtg cagcatgacc ctgtggaacg    300
gcgtactgcc tttttacccc cagccccggc atgccgcagg cttcagcgtt ccactgctca    360
tcgttattct agtgtttttg gctctagcag caagcttcct gctcatcttr ccggggatcc    420
gtggccactc gcgctggttt tggttggtga gagttcttct cagtctgttc ataggcgcag    480
aaattgtggc tgtgcacttc agtgcagaat ggttcgtggg tacagtgaac accaacacat    540
cctacaaagc cttcagcgca gcgcgcgtta cagcccgtgt cggtctgctc gtgggcctgr    600
agggcattaa tattacactc acagggaccc cagtgcatca gctgaacgag accattgact    660
acaacgagca gttcacctgg cgtctgaaag agaattacgc cgcggagtac gcgaacgcac    720
tggagaaggg gctgccggac ccagtgctct acctggcgga gaagttcaca ccgagtagcc    780
cttgcggcct gtaccaccag taccacctgg cgggacacta cgcctcggcc acgctatggg    840
tggcgttctg cttctggctc ctctccaacg tgctgctctc cacgccggcc ccgctctacg    900
gaggcctggc actgctgacc accggagcct tcgcgctctt cggggtcttc gccttggcct    960
ccatctctag cgtgccgctc tgcccgctcc gcctaggctc ctccgcgctc accactcagt   1020
acggcgccgc cttctgggtc acgctggcaa ccggcgtcct gtgcctcttc ctcggagggg   1080
ccgtggtgag tctccagtat gttcggccca gcgctcttcg cacccttctg gaccaaagcg   1140
ccaaggactg cagccaggag agagggggct cacctcttat cctcggcgac ccactgcaca   1200
agcaggccgc tctcccagac ttaaaatgta tcaccactaa cctgtgaggg ggacccaatc   1260
tggactcctt ccccgccttg ggacatcgca ggccgggaag cagtgcccgc caggcctggg   1320
ccaggagagc tccaggaagg gcactgagcg ctgctggcgc gaggcctcgg acatccgcag   1380
gcaccaggga aagtctcctg gggcgatctg taaataaacc tttttttctt ttgtttttta   1440
aaaaaaaaaa aaaaaaaaaa aaaagggcgg ccgc                               1474

<210> 1098
<211> 1037
<212> DNA
<213> Homo sapiens

<400> 1098
ggccgctctc ccccctcccc gacacacact cacaggccgg gcattgatgg taatgtatgc     60
gaggaaacag cagagactca gtgatggctg tcacgaccgg aggggggact cgcagcctta    120
ccaggggggt gatgttttac aggcacttaa gtattcatcg aagagtcacc ccagtagcgg    180
tgatcacaga catgaaaaga tgcgagacgc cggagatcct tcaccaccaa ataaaatgtt    240
gcggagatct gatagtcctg aaaacaaata cagtgacagc acaggtcaca gtaaggccaa    300
aaatgtgcat actcacagag ttagagagag ggatggtggg accagttact ctccacaaga    360
aaattcacac aaccacagtg ctcttcatag ttcaaattca cattcttcta atccaagcaa    420
taacccaagc aaaacttcag atgcacctta tgatyctgca gatgactggt ctgagcatat    480
tagctcttct gggaaaaagt actactacaa ttcggcacga gacaagatgg cagtcaacag    540
cttcccaaaa gatagggatt acagaagaga ggtgatcaca gacatgaaaa gatgcgagac    600
gccggagatc cttcaccacc aaataaaatg ttgcggagat ctgatagtcc tgaaaacaaa    660
tacagtgaca gcacaggtca cagtaaggcc aaaaatgtgc atactcacag agttagagag    720
agggatggtg ggaccagtta ctctccacaa gaaaattcac acaaccacag tgctcttcat    780
agttcaaatt cacattcttc taatccaagc aataacccaa gcaaaacttc agatgcacct    840
tatgattctg cagatgactg gtctgagcat attagctctt ctgggaaaaa gtactactac    900
aattgtcgaa cagaagtttc acaatgggaa aaaccaaaag agtggcttga aagagaacag    960
agacaaaaag aagcaaacaa gagcagagac tcacagtagt tctacgccag tacagcaccc   1020
catcaaacca gtggttg                                                  1037

<210> 1099
<211> 775
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<400> 1099
aacggggntc ttctactgga aaagccccac actaatttaa tgtatgggaa ggcgtaatat     60
aaaaggcctc caccaactgc ctgaagcacg gttaaaattg ggaagaagta aagtgcagca    120
taaatacttt taaatcgatc agatttccct aacccacatg caatcttctt caccagaaga    180
ggtcggagca gcatcattaa taccaagcag aatgcgtaat agataaatac aatggtatat    240
agtgggtaga cggcttcatg agtacagtgt actgtggtaa cgtaatctgg acttgggttg    300
taaagcatcg tgtaccagtc agaaagcatc aatactcgac atgaacgaat ataaagaaca    360
ccaactggat cactcacaag taaggtgata atagctgcca tgctgcattc aaataatgca    420
gtgatgtgtt ggaaaagtgc gctggaactc tttttccccg agtaccattc aatgaagaac    480
caatgtaaaa ccagaggaag cattgccata aatccaagat agagccaatc ataaagttca    540
ggagattctg tgcaaggctg acaatatttc tgtgcattcg ttctctgtcc tcttgggcat    600
accccacatt ctccatatat ttcagttgag ccatttttaa ataatagggt cttcccacaa    660
taaagtccaa ggcatgctgg ttgaatatcg acagccatgg gccgcctgaa ggtttttttc    720
gagaagcact agatcagcgg atctggcagc tgcaccgaac atccgggcca cagct         775

<210> 1100
<211> 1120
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1111)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1118)
<223> n equals a,t,g, or c

<400> 1100
ccgccgagct cgctgtggcc cggatgttcg gtgcagctgc cagatccgct gatctagygc     60
ttctcgaaaa aaaccttcag gcggcccatg gcatgccttg gactttattg tgggaagacc    120
ctattattta aaaatggctc aactgaaata tatggagaat gtggggtatg cccaagagga    180
cagagaacga atgcacagaa atattgtcag ccttgcacag aatctcctga actttatgat    240
tggctctatc ttggatttat ggcaatgctt cctctggttt tacattggtt cttcattgaa    300
tggtactcgg ggaaaaagag ttccagcgca cttttccaac acatcactgc attatttgaa    360
tgcagcatgg cagctattat caccttactt gtgagtgatc cagttggtgt tctttatatt    420
cgttcatgtc gagtattgat gctttctgac tggtacacga tgctttacaa cccaagtcca    480
gattacgtta ccacagtaca ctgtactcat gaagccgcta cccactatat accattgkat    540
ttatctatta cgcattctgc ttggtattaa tgatgctgct ccgacctctt ctggtgaaga    600
agattgcatg tgggttaggg aaatctgatc gatttaaaag tatttatgct gcactttact    660
tcttcccaat tttaaccgtg cttcaggcag ttggtggagg ccttttatat tacgccttcc    720
catacattat atwagtgtta tctttggtta ctctggctgt gtacatgtct gcttctgaaa    780
tagagaactg ctatgatctt ctggtcagaa agaaaagact tattgttctc ttcagccact    840
ggttacttca tgcctatgga ataatctcca tttccagagt ggataaactt gagcaagatt    900
tgcccctttt ggctttggta cctacaccag ccctttttta cttgttcact gcaaaattta    960
ccgaaccttc aaggatactc tcagaaggag ccaatggaca ctgagtgtag acatgtgaaa   1020
tgccaaaaac ctgagaagtg ctcctaataa aaaagtaaat caaaaaaaaa aaaaaaaaac   1080
tcgagggggg gcccggtacc caattcgccc nagagtanta                         1120

<210> 1101
<211> 759
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (114)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (666)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (732)
<223> n equals a,t,g, or c

<400> 1101
gggtcgaccc acgcgtcckg tgacacgtag caacggggct ggttcagggt ctgaaacaga     60
gtttgggggt tgtttgggat tagtgaagct actgcctttg ccgccagcgc agcntcagag    120
tttgattatt tgcaatgtca ggctttgaaa acttaaacac ggatttctac cagacaagtt    180
acagcatcga tgatcagtca cagcagtcct atgattatgg aggaagtgga ggaccctata    240
gcaaacagta tgctggctat gactattcgc agcaaggcag atttgtccct ccagacatga    300
tgcagccaca acagccatac accgggcaga tttaccagcc aactcaggca tatactccag    360
cttcacctca gcctttctat ggaaacaact ttgaggatga gccaccttta ttagaagagt    420
taggtatcaa ttttgaccac atctggcaaa aaacactaac agtattacat ccgttaaaag    480
tagcagatgg cagcatcatg aatgaaactg atttggcagg tccaatggkt ttttgccttg    540
cttttggagc cacattgcta ctggctggca aaatccagtt tggctatgta tacgggatca    600
gtgcaattgg atgkctagga atgtttggtt attaaactta atgagtatga caggtgtttc    660
atttgnttgt gtggcaagtg tccttggrta ttgkcttctg sccatgatcc tactttccag    720
tttgcagtga tnttttcttt gcaaggatgg tagggattc                           759

<210> 1102
<211> 3674
<212> DNA
<213> Homo sapiens

<400> 1102
ggcagagcta cttcttgctg cctcacggtt gctgttgcag acccaggagt ctctgaaggc     60
ttccgcggct ttggggccgg ttgtgagatg ccaggcagag gccgctgccc ggactgcggc    120
tccacggagc tggtggaaga ctcgcactat tcgcagagcc agctggtgtg ctccgactgc    180
ggctgcgtgg tcaccgaggg ggtccttacc actaccttca gcgacgaggg caatctccga    240
gaggtaacat attcccgaag cacaggggaa aacgaacaag ttagtcgcag ccagcaacga    300
ggtctccggc gaktgagaga cctttgtcga gttctgcagt tgccaccaac atttgaggat    360
accgcggttg cctactacca acaggcatat cggcactctg gcatccgagc ggccaggctg    420
caaaagaagg aggtgttggt tgggtgctgc gtcttaatca cctgccgaca gcataactgg    480
cccctaacaa tgggggccat ctgcacgctg ttgtatgcag atttggatgt gttttctagc    540
acttacatgc agatagtgaa gctcctggga ctggatgtgc catctctgtg cttggcagaa    600
ctggtgaaga cctattgcag cagcttcaaa ctgttccaag cttcaccttc tgtgccagcc    660
aaatacgtgg aagacaaaga gaagatgctg tctcgaacaa tgcagttggt ggagctggca    720
aatgagacgt ggctggtgac cgggaggcat cccttgcccg tcatcactgc tgcgactttc    780
ctggcttggc agtcgctgca gcctgcagat cggctttcat gttcccttgc ccgattttgt    840
aaattggcaa atgtggacct gccctacccg gcgtcctccc gcctgcagga gctgctggct    900
gtgctgctgc ggatggctga gcagctggcc tggttacgag ttctgagact tgacaaacgg    960
tctgtggtga agcacatcgg tgaccttctc cagcaccgcc agtcactggt ccgctctgcc   1020
tttcgggatg ggacagcaga agtggagacc cgagagaagg agccaccggr gtggggacag   1080
gggyaaggag aagsggaggt gkgaamyaat tccttaggtt taccccaggg gaagcggccg   1140
gccagtcctg cccttctctt gccaccctgc atgttgaagt ccccgaagcg gatctgccct   1200
gtaccccctg tctccactgt cactggagat gagaacattt ctgatagtga aatagaacag   1260
tatttgcgta cccctcagga agttagggac tttcagagag cccaggctgc tagacaggct   1320
gccacgagtg tccctaaccc tccctgatgg atatccactg ggagcacttc atcctgttct   1380
gacagcttga taacattcct gttataacca aggatggaag tgtacaccag tccgtaggta   1440
ttgcttttct tgtttgaagg aaccaagagg ggctctgcca ttagttggac cctgggtcct   1500
ggagtaaagt caggagtgca gggatgacta taggtaggag agattcccat cccttggtgt   1560
gggagagcaa gttgcctatg tccatgttct gtgagatggc tttcctcata gatggatggg   1620
aaaatgtcag gctctttgct gctggtttga attggacaca ctgctgcggc tcctcctgca   1680
ggcctgaggg ggcttccctc tgcttgtgga gtggttggca ttcccagcag tatcaaccct   1740
cagaggagcg ggaactgggg aattctggcc ctacgtgcat tcacaggcaa tgatgggttt   1800
gtgtgtatgg tgtcatgaga tcctctacct cataacaaaa ggacagtggg tagactaagg   1860
cagtagctca aagggctttg caaaatttta atatattaaa acaagaggca tctgctagaa   1920
aacattctat tgtataaaac ccgagttctt aaaaacatgt tttctttggc actttcattc   1980
cctccctccc ctttccccag catattgcaa aaagctctcc agtgctaagg cattggcagg   2040
gtgtgtaaac agcagccagc atatgtggaa gaataataca aagctttttt ttttcttcta   2100
atatgtctgt gcagcaagca taaataacag gacccattcc aaggagtgtg tgtgggtttt   2160
ccccctcccc tgtgtcctct gtcaccttgg tgatgaggcc agagtgatgt gaagactggg   2220
agggaaccct aggtcagacc ttggtttcct gttgttcttc ccaagaccca gggttccctc   2280
ggtttccatt tggtcctgta gtgaaatgct ggtggttggt tttaggttgg ggaaaagacg   2340
ggtgctggtg tttaaaagga gtaaaggcat aggcccctca tgacctgcag ggaccccagc   2400
cactgcctct gggcttggct tgagctcctg ggagtcggga agctggtttg acattttgta   2460
ggtttctctc tactgtggag ctggagatca aatgattggg atggttcttc ctctggcctt   2520
acggaggcaa ggaagtgctc ttccttagtc ccgtggtgtt gtaaggctga gactagggag   2580
atgggtcttg taactgaaaa gtaactgctt ctccaaacac cacctgcagc tttctggggc   2640
accattgttt acaggactag ctttagggca tgactagatt ctgccccagt tccacctgcc   2700
ctctccctct actcccctca gttcacccac aggcacctgg cagtcagctg ttgaggtgca   2760
gggcctcagc tttgtcccgg tgtgccacct ctgaaccctg ctgtctggtt taagtaccac   2820
tcctgtggga atggtggcat tgttcctagt tgtgcccggt tcccactccc ctcccccagg   2880
actggttgat gtctagagct gcctttcacg tggccccacc ctcccctctt gcatagtgga   2940
tctgaaaagc agcaccttgt gacttaacat cacctgcttc atgtgctggg ctagctctcg   3000
tgccagccaa actcgggagg aaaagggacc taggatctag gcaggggctg ggctgaaatc   3060
agtagagggc agggaggaaa gaacacagtt cccacgctct catctctgct ttgctggtga   3120
ggctgatggc ccccagtgag gccgcatgga cagtaggcgg ggtgggagta cttggggagg   3180
gtgcacctgg gatgtgctgt gccctttcac acagacggag gccttccccg ttcctgggag   3240
ggcaccgaca gtcagactgc cccgggctgg acggaaatgt attatgcgtg tttctgggat   3300
tgtctgtcgc taccccagag ggatgccctc taggcaagtg gggaacatcc scctgtgggc   3360
ttcctccagc catcggctcc tctgcctcca acctgctgac tacggagaca ccttggaggg   3420
ccccgaggag cgggggaacg agccgcgtgg ccagcccgtc taccgcgtcg cccgccccac   3480
cttagacggt agtttcgctc ttccagagtc cggtcttcat gcagccgccg ctggctacct   3540
ccgcgcccat cagggtgacg tcgtcgtact tgcccccctt gggggcgccg tttaggctgg   3600
cggcgttgag cgggtacgag cggcgatggc tctccttctc cagcgcgccg ccgcccttga   3660
gactgtcgcg gctg                                                     3674

<210> 1103
<211> 1857
<212> DNA
<213> Homo sapiens

<400> 1103
ggggccgctg cgcggtatcg acgagtactc ggacgcggsa cggcggycgc gccctgcagg     60
acgcggackg gccctggcgg catcaacatg ctgctcaaca acggcttcag ggagtcggac    120
cagcttttca aacaatacag aaatcatagc ccactaatga gttttggagc cagctttgtc    180
agttttttga atgccatgat gacatttgag gaagaaaaaa tgcagttggc atgtgatgac    240
ttaaaaacca cagaaaaact gtgtgaaagt gaagaggctg gagtaattga aacaatcaag    300
aataaaatta agaagaacgt tgatgtccga aaatccgccc cctctatggt tgatcggctt    360
cagaggcaga taatcatagc tgactgccag gtttacctgg ctgtgctttc atttgtaaaa    420
caagaattgt cagcttatat caaaggtggg tggatcctta ggaaagcctg gaagatttac    480
aataaatgct atctggacat caatgccctt caggagctgt atcagaagaa gctaactgaa    540
gagtccttga cttctgatgc tgcaaatgat aatcacattg tggctgaagg ggtgtctgag    600
gagtctctga acagactgaa aggtgctgtt agctttggat atggcctttt tcacctttgc    660
atatccatgg tgcccccaaa cctgctcaaa atcatcaacc tgctgggttt tcctggagac    720
cgcctacagg ggctttcttc actgatgtat gcaagcgaaa gtaaggacat gaaggcccct    780
ttagctacat tagctctgct ctggtatcat actgtagtcc gcccgttttt tgccttggat    840
ggcagtgata acaaggcagg cctggatgaa gctaaggaaa ttctccttaa aaaagaagct    900
gcttatccaa attcttccct ctttatgttt ttcaagggac ggatacaacg actagagtgt    960
caaatcaaca gtgccttgac atctttccac actgctttgg aacttgcagt agaccagaga   1020
gaaattcaac atgtctgtct gtatgaaatt ggttggtgca gcatgataga gctcaatttc   1080
aaggatgcat ttgattcctt tgagaggcta aaaaatgagt ccaggtggtc ccagtgctat   1140
tatgcctact tgactgcagt ttgtcaggga gccactggtg atgtggatgg ggcacagatt   1200
gtctttaaag aagttcagaa actcttcaaa aggaaaaaca atcagattga acagttctcg   1260
gtgaaaaagg cagagcgatt tcggaagcaa accccaacca aagcgctctg tgtgttggcg   1320
tctattgaag tgttgtactt gtrraaagct cttccaaact gttccttccc caacctgcag   1380
aggatgagtc aagcttgcca tgaagtggat gactcatctg ttgttggatt aaagtatttg   1440
cttcttggtg ccatacacaa atgtctagga aactcagaag atgctgttca gtacttccag   1500
cgagctgtta aagatgaatt gtgtcgtcag aataatttat atgttcagcc gtatgcctgt   1560
tatgaacttg gctgtcttct attagacaaa ccagagactg taggaagagg cagagctcta   1620
cttcttcaag caaaggagga tttctctggc tacgactttg aaaacagatt gcatgtccgc   1680
atccatgctg ctctggcctc tctgagggaa ttggttcctc agtgacagac ccggaacacc   1740
cgctccgtcc ctccccaccc agggtccgca ctttaaaata aaagcagagg acaaaaaaaa   1800
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaggg cggccgc      1857

<210> 1104
<211> 1545
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1111)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1122)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1182)
<223> n equals a,t,g, or c

<400> 1104
cgctgctact gtggctgttg ccgcgtttac cagcattagc gcgccggata tgaaggtcaa     60
cgatcgtgtc gcggctgaac gccaacatgt gctggcgttt gccctcgcgg gcggcgtgct    120
gctgttgatg gctgtggtgg tggcgctgtc gtttggtcgt gatgcgcacg gctggacgtg    180
ggcgagcggg gcgttgctcg aggatttaat gccctggcgc tggccgcgaa ttatggcggc    240
gctgtttgcg ggcstcatgc tggcggtkgc gggctgtatt attcascrac tgaccggaaa    300
cccratggca agcccggaag tgctggggat tagctccggc gcggcgtttg gcgtggtgtt    360
gatgctgttt ctggtgccgg gtaatgcctt tggctggctg ttacctgcag gcagtctcgg    420
cgcgscggtg acgctgttga tcattatgat cgccgccggc cgcggtggat tttccccaca    480
ccgtatgtta ctggcgggga tggcgttaag caccgcgttc accatgcttt tgatgatgtt    540
gcaggcaagt ggtgacccgc gaatggcgca agtgctgacc tggatttccg gttcgaccta    600
caacgcgacc gatgcgcagg tctggcgcac cggaattgta tggtattttg ctgcgattac    660
cccgctgtsc cgcgctggct gaccatttta ccgctgggtg gtgataccgc ccgagccgta    720
ggaatggcgc tgacgccgac gcgaattgcg ctgctgctgt tagcggcttg cctgacggcg    780
accgcgacga tgactattgg accgttgagt tttgttggtt taatggcacc gcatattgcg    840
cggatgatgg gctttcgacg gacgatgcca cacatcgtaa tttcggcgct ggtgggtggt    900
ttactgctgg tgttcgctga ctggtgtggg cggatggtgc tgtttccatt ccagatcccg    960
gcggggctgc tgtcaacctt tatcggcgcg ccatatttta tctatttgtt gagaaagcag   1020
agccgttaat ttttccatat aacggccctg tacgcctgga cggataaagc gtttacgcga   1080
caacggatgc ccgatgcgac gctggcgcgt nttatcgggc cnacaaacgg ccccgaattg   1140
taggtcggat aaggcgttca cgccgcatcc gacaaaccat gntggatcac aacttcgcaa   1200
acacccgacg tgcagcatcg atggtgttat tgatatcttc catgctgtgc gccacggaca   1260
taaagcccgc ttcaaacgct gacggtgcca ggtaaacacc ttcgtccagc atcatatgga   1320
agaaacgytt aaagcgttcc acgtcacagg ccatcacatc ctgatagcac gtcacggact   1380
cggcgtcggt aaagaaaata ccgaacatgc cgccaacgtg gttaacgacc agcggaattc   1440
cggcttcttc tgccgcttcc agcagacctt ttgccagacg tgttgtcagc tcatccagcg   1500
tttcgtgaac gcccggctgc gcgacttcat tcagacaggc gaaac                   1545

<210> 1105
<211> 1710
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (125)
<223> n equals a,t,g, or c

<400> 1105
ggcacgagcn gatgcatctg gctgtgagct gtgactagtc atatactagt tgtgtcattt     60
tgaacaggtt acctaacctc tggctcctca gtttgttcat ctgtttaaaa attgtgggaa    120
taacngttcc tgctgggtca ttgcaagatg tcagggagac gtgtcaagtg cttagaatag    180
ggcttggcat aagtagagtc tcagtagggt aggtgttatt taatcccaga aataactgac    240
aactttggaa gatgagagtg aatgtctccg atcattaatt tatttaacaa atacttatct    300
agtactatgt gcccggcgct gtagacactg ccatgtttta tctcattcaa tattcacagt    360
gactgcccag tgaatggtat tgcctccatc ctctgagaag gtaaagagcc tatcccagac    420
cccacgagtg gaggcgtcag ggaggggttc ttggcaggag atgggtcttg tagaaaggct    480
tctgctttgc tttcactcac ggcctgtggc agtttgctca gacagctccc atcaggacac    540
cattggcagc ttttgcatga ccctgcctcc cagggtcttc ctgcgttttt ccttaagttg    600
ccttattctt tggttgtttc cctacttgtt tttgttagac tgtgggagga agaaatccat    660
ttcaaatctg ctgaaacctg ttaccaagca acagcagtga ttaaaagcaa cctgatgagt    720
gagtaaagaa ttagggtttc agacctgtag ttaatgatgg tctctgtctc cctgctgccc    780
tgcattccct tcccttccgt tcactgctgg gtgaaggagg gcttgctgca ttttggaagt    840
taagggaacc aataaggtga ctcttttgca gattggaata tggtgctcag ccagccatat    900
ggaagcactg tcctggcgtg atctgccctg ggctgttggc tctctgagtg ctgtcttggg    960
aggagcactg cccttcagaa cagaagagat ggcttccagt cccctctccc ccttctccca   1020
gtctctctga ggctgcttgt tgggtattgg gcgtgctgtg tactaactca ctcccgtctc   1080
ttgtctcatt atctgaaatg catccccttt tgcagaaagg gctcaaacgg agccttcagt   1140
tctgctcctc tgcatagccg tagctcagat cctagctcar gatgtcttgt ctgggaaggg   1200
caaaacatgg tccccagtgt agcattttca ctgggttgat tatctcagtg gtggatcatc   1260
tatcaccctt gtgtggtgac tttgtgaatt atctgcctga gtgccacttc ccttccaccc   1320
taatcactgc aggctcaggg agcaagaaat aaaatcatga aatgcattcc aaataaaatt   1380
accttttggc tgggtgcagt ggctcacacc tgtaatctga gcactttggg aggctgaggt   1440
gggtggatcg cttgaggtca ggagttcaag accagcctgg ccaacatggc aaaaccccat   1500
ctctacaaaa aatacaacag caaaaaaatc agccaggcta gctggtgtgc gcctataatc   1560
ccagctactt gggagggagg ctgaggcaca agaattgctt gaacccagga ggtggaagtt   1620
cagtgagccg agatcgcacc cctgcactcc agcctgagca acagagtgag actctgtctc   1680
aaaaataaaa aaaaaaaaaa aaaactcgag                                    1710

<210> 1106
<211> 374
<212> DNA
<213> Homo sapiens

<400> 1106
gatgtttgtc tacatcgtct tcttgttcgg gttttccaca gcggtggtga cgctgattga     60
agacgggaag aatgactccc tgccgtctga gtccacgtcg cacaggtggc gggggcctgc    120
ctgcaggccc cccgatagct cctacaacag cctgtactcc acctgcctgg agctgttcaa    180
gttcaccatc ggcatgggcg acctggagtt cactgagaac tatgacttca aggctgtctt    240
catcatcctg ctgctggcct atgtaattct cacctacatc ctcctgctca acatgctcat    300
cgccctcatg ggtgagactg tcaacaagat cgcacaggag agcaagaaca tctggaagct    360
gcaaagagcc atca                                                      374

<210> 1107
<211> 1404
<212> DNA
<213> Homo sapiens

<400> 1107
ctcttgcccg gctgcacagg agtttcttta aggagtttcc ccggtgtgcc tcggcagcct     60
tgcgctgctc taatggtccg gacttccgtg tgctccccac aggtgcagga agccgccgcc    120
cagccatgga cggggaggag cagcagccac cgcacgaggc caacgtggaa cctgttgtgc    180
cgtcagaggc ttcagagccg gtgcccaggg tgctttctgg agacccccag aacctgtccg    240
acgtggacgc cttcaacctg ctcctggaga tgaagctgaa gcggcggcgt cagcggccca    300
acctgccgcg cactgtgacc cagttggtgg ctgaggacgg gagcagggtg tacgtggtgg    360
ggacagccca cttcagcgac gacagcaaga gggacgttgt gaagaccatc cgggaggtgc    420
agcctgacgt ggtggtcgtg gagctctgcc aatatcgtgt gtccatgctg aagatggacg    480
agagcacgct gctgcgggag gcccaggagc tcagcctgga gaagctgcag caggccgtga    540
ggcagaacgg gctcatgtcg gggctgatgc agatgctgct gctgaaggtg tctgcacaca    600
tcaccgagca gctgggcatg gccccaggtg gcgagttcag ggaggccttc aaggaggcca    660
gcaaggtgcc tttctgcaag ttccacctgg gtgaccgacc catccccgtc accttcaaga    720
gggccatcgc agcgctctcc ttctggcaga aggtcaggct ggcttggggc ctgtgcttcc    780
tgtcagaccc catcagcaag gatgacgtgg aacgctgcaa gcagaaggac ctactggagc    840
agatgatggc cgagatgatt ggcgagttcc cagacctgca ccgcaccatc gtctcggagc    900
gcgacgtcta cctaacctac atgctgcgcc aggccgcgcg gcgcctcgag ctgcctcggg    960
cctctgacgc cgarcccarg aagtgcgtcc cctccgtggt cgtgggcgtc gtgggcatgg   1020
gccacgtgcc tggcatcgag aagaactgga gcaccgacct caacatccag gagatcatga   1080
ccgtgccccc gccgtccgtc tccggcagag tgtctcggtt ggccgtgaag gccgccttct   1140
tcggcctgct gggctacagc ctgtactgga tgggccgccg caccgcgagc ctggtcctgt   1200
cgctgcccgc cgcgcagtac tgcctgcaga gggtgaccga ggcccggcac aagtaggaga   1260
ctgctccccg cccgctcggg cccctgagga gccagtgccc ccgcggcayt tctgggtgcc   1320
aagtgcatcc taagcccgcc cgaggccctt gscamcmccc atgggggktc ttgggcccgg   1380
ctttggttgc cttcctgggc cagt                                          1404

<210> 1108
<211> 2776
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (162)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1271)
<223> n equals a,t,g, or c

<400> 1108
cgcgctcgcc cacccckcgg ccccgcagga tgaagaagga cgagtcgttc ctgggcaagc     60
tgggcgkcac cctggccagg aagcggaggg cgcgcgaggt gagtgacctg caggaagaag    120
gcaagaatgc catcaactca ccgatgtccc ccgccctggc gnatgttcac cctgaagaca    180
cccagctcga ggagaacgag gagcgcacga tgattgaccc cacttccaag gaagacccca    240
agttcaagga actggtcaag gtcctcctcg actggattaa tgacgtgctg gtggaggaga    300
ggatcattgt gaagcagctg gaggaagacc tgtatgacgg ccaggtgctg cagaagctct    360
tggaaaaact ggcagggtgc aagctgaatg tggctgakgt gacacagtcc gaaatagggc    420
agaaacagaa gctgcagacg gtgctggaag cagtacatga cctgctgcgg ccccgaggct    480
gggcgctccg gtggagcgtg gactcaattc acgggaagaa cctggtggcc atcctccacc    540
tgctggtctc tctggccatg cacttcaggg cccccatccg ccttcctgag catgtaacgg    600
tgcaggtggt ggtcgtgcgg aaacgggaag gcctgctgca ttccagccac atctcggagg    660
agctgaccac aactacagag atgatgatgg gccggttcga gcgggatgcc ttcgacacgc    720
tgttcgacca cgccccggat aagctcagcg tggtgaagaa gtctctcatc acttttgtga    780
acaagcacct gaacaagctg aatttggagg tgacggaact ggagacccag tttgcagatg    840
gcgtgtacct ggttctgctc atgggccttc tggaagacta ctttgttcct ctccaccact    900
tctacctgac tccggaaagc ttcgatcaga aggtccacaa tgtgtccttc gcctttgagc    960
tgatgctgga cggaggcctc aagaaaccca aggctcgtcc tgaagacgtg gttaacttgg   1020
acctcaaatc caccctgagg gttctttaca acctgttcac caagtacaag aacgtggagt   1080
gacgggggag ctgtggatgg tggcaggagt gtcccagcaa gaaaggcggc atccgtctgt   1140
gccctgtgcc tttccaggga gcmaggcgcc atgggcttct ggtcctgcag ctcacacttt   1200
gagggagccc caggatccca gccaggagaa gcctcaggcc ggagaactgg aggccggaga   1260
ggagcttgcg nctgtgtgtg cggctgccta cactatagaa ttactggaca ctgtggcctt   1320
aaacctgcac cgcatagaca aggatgtgca gaggtgtgac cgcaactact ggtacttcac   1380
gccccccaac ctcgagaggc tcagagacgt catgtgcagc tacgtgtggg agcacctgga   1440
cgtgggctat gtgcagggca tgtgcgatct gctggcgcct ctcctggtca ccctcgacaa   1500
tgatcagctg gcctacagct gcttcagcca cctcatgaag aggatgagcc agaacttccc   1560
caacggggtg ccatggacac ccactttgcc aacatgcgct ccctcatcca gatcctggac   1620
tcagagctgt ttgagctgat gcatcagaat ggagactaca cccacttcta cttctgttat   1680
cgctggttcc tgctggattt taagagagaa ctgctgtatg aggatgtgtt tgctgtgtgg   1740
gaggtgatct gggcagccag gcacatctca tcggagcact ttgtcctgtt catcgccctc   1800
gccctggtgg aggcctaccg agagatcatc cgtgacaaca acatggactt cactgacatc   1860
atcaagtttt tcaatgaacg tgctgagcat cacgatgccc aggagatcct gcggattgcc   1920
cgggacctcg tccacaaggt acttccctga aaaccacgtg taagaagtga tgcttttgcc   1980
agtggatgat ctggaatgcg accggagcac ttgctctgag gaatcccagg gtgactctgt   2040
cggggaagaa tccggtcaca gcctcccctc agagacaggc ctcagttcga gggcagccca   2100
ttatctgtcg cagaatctgc catgtccctg agactgcggg aggcagggga tgcatgggtg   2160
tccccatctg tccctggtga gaagcaaggc tagctctgcc ttccacatgc ttctcaggat   2220
gccaagaggc ctaggaaccc agaaaccccc ttggaggagc tgtgtatgcg ggggtgccag   2280
gaagggcata gctcctgccc ccaggcctag gcatgctgct tgctcggcca tccccacttc   2340
ctcctctacc ccaacacatg caggctaggc cttgccctgg aacgtggagg ccctgcccgg   2400
ggctggggcc tagtccagca gccaccaaag tctggcagac tttctgcatt tgagaaacat   2460
gacaaagggc cccgcagccc ttctgcaccc agcacagcct gcccagccca gccctgcccc   2520
cgggcactgc acagcctgtc tgggggccag accaccccat tgtccatcct tgttgtccgt   2580
gagtccttgg cctccaccaa gcacgtgtgg ccattgtgtg cctgccttag tgactccgtg   2640
gttttgtgag gagcagagtg tgtatgattt ttgcctcaga aactatactc ttctgtgtaa   2700
cagaccaata aacaacattt gtcaacaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2760
aaaaaaaaaa aaaaaa                                                   2776

<210> 1109
<211> 1634
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1611)
<223> n equals a,t,g, or c

<400> 1109
ttcaaaaanc tattttaggt gacactatag aaggtacgcc tgcaggtacc ggtccggaat     60
tcccgggtcg acccacgcgt ccgtyagaga gtaaaacttg tctcggcaca gagtcaagta    120
aagaaagcca acatacagtg gagcccctgg ggagcagtcc ctgctgtcat cagatggacg    180
tgcaaacaga ttccccaagc ctttcggtaa ctgcaggaaa ggaccacatg gaggagctgc    240
tctgcaggct gaagccacgt tagcgctcca cacccagtcc tccgagacag cagggagccc    300
gtctgggcca gactcttctg aggatgcttg tgaggatgac agtcgcttgc agctggctca    360
aacagaggcc tgccaggatg tggccagaat agagggcatt gctgaagacc ctaaggtgtt    420
tctttccagc aagtcaaaga cagagccgtt gatttcacca ggctgtgacc gtatacctcc    480
tgcattgatt tctgagggta aatattcaca ggctcagagg aaagaactcc gtttgccact    540
tcgggatgct tctgaggcgt tgcccacaga ccaacttgag aacaatgaat taaatgagct    600
gcagcagcct gatcttacag acagtgatgg aaaatcacca caggcgcagg ctgactcaga    660
cggttctgag aatgtgctct gtggaaataa tcaaatatct gacttargca tactgcttcc    720
agaggtgtgt atggccccag aggaaaaggg agataaagac gaccaactca acaaagaaac    780
agaagactat ttgaacagcc ttttagaagg atgtttaaaa ratactgaag attccctttc    840
ctatgaagat aaccaagacg acgactccga tctccttcaa gatctctctc ctgaagaagc    900
atcctatagt ctccaggaga atctgccttc tgatgagagc tgtctttctc ttgatgatct    960
tgccaaaagg atagagattg cagaggttgt tcctactgaa ggattggtct ccatattaaa   1020
gaagaggaat gatactgtag gagatcatcc tgcccaaatg caacacaaac catctaagcg   1080
aagagtgaga ttccaagaaa tagacgatag cttggatcaa gatgaagttg gaggtggctc   1140
ctgtattttg ctggtcttgc tgtgcatagc aacggttttc ctcagtgttg gaggaactgc   1200
attatactgc actttcggtg acatggagtc acctgtttgt actgactttg cagacaacat   1260
ggacttctat tacactaagt tacttcaggg agtggcagaa ctgaagcact ggatctacct   1320
ctcctagcag cattccagac acagacatgc tggcagtgag agtgaaaggc gggagacttt   1380
ctaaacagtt tttctttcag gaattctgta gcattccccc ttccctctgt taggaaccaa   1440
ggacatcaga aatagcaact ttaagtggca agccggagga actctgttag aataatccac   1500
acagtgaggc aaatatcaat ctaagcattg tggatgggaa ggaatggtct ttgggagaga   1560
gcatatccat ctcctyctca ctgcctccta atgtccatgg aggtacactg nagcagaatt   1620
taaacagggt agtt                                                     1634

<210> 1110
<211> 1270
<212> DNA
<213> Homo sapiens

<400> 1110
aggaggaaac gcaacctggg cggctcctag gacgcagaga cgccgtcccc gccttcattg     60
agcccaacgt gcgcttctgg atcaccgagc gccaatcctt tattcgacga tttcttcaat    120
ggacagaatt attagatcct acaaatgtgt tcatttcagt tgaaagtata gaaaactcga    180
ggcaactatt gtgcacaaat gaagatgttt ccagccctgc ctcggcggga ccaaaggcaa    240
cagtgcatcc cgacagcagc aacctgatcc ccaagctttt tcgacctgca gcgttcctgc    300
ctttcatggc gcccacggta tttttgtcaa tgacgccact gaaagggatc aagtccgtga    360
ttttacctca ggttttcctc tgtgcctaca tggcagcgtt caacagcatc aatggaaaca    420
gaagttacac ttgtaagcca ctagaaagat cattactaat ggcgggagcg ttgcttcttc    480
aactttctta ggagtaatcc ctcagtttgt ccagatgaag tatggcctga ctggcccttg    540
gattaaaaga ctcttacctg tgatcttcct cgtgcaagcc agtggaatga atgtctacat    600
gtcccgaagt cttgaatcca ttaaggggat tgcggtcatg gacaaggaag gcaatgtcct    660
gggtcattcc agaattgctg ggacaaaggc tgttagagaa acgctagcat ccagaatagt    720
gctgtttggg acctcagctc tgattcctga agtcttcacc tactttttta aaaggaccca    780
gtatttcagg aaaaacccag ggtcattgtg gattttgaaa ctgtcttgta ctgtcctggc    840
aatgggactg atggtgccat tttcttttag tatatttcca cagattggac agatacagta    900
ctgtagtctt gaagagaaaa ttcagtctcc aacagaagaa acagaaatct tttatcacag    960
aggggtgtag gcgtgagttt taggtgaatt tatgtggttc ctgcttgaaa accttcccct   1020
ctccaggttc ggtttagaga actttgccac aggtcttctg gggtttttaa ggctggctgg   1080
agaagacagt gggagggtgc cccgtctgac acccctgggg ttgctgaggg aacggttgga   1140
gtggggatcg gcctgcgaaa ggatactgtg aaatcactaa ttaactaata aacctgtctc   1200
aagttgagga tttgaaraaa aaaaaaaaaa aaaaaaaaaa aaagtcgtat cgatgtcgag   1260
cgatcatgat                                                          1270

<210> 1111
<211> 986
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (278)
<223> n equals a,t,g, or c

<400> 1111
attttttttt tttttttcca aagaaaagtc acaaatacat atgtacacat gcacgccaac     60
cccactggga cagacaccag gatgttggga tgtggggagt ggggagtggg ggttcccaag    120
cacagcaggg tggtgggtgg gaccctccaa ccccagcccg ccccaccctc tccacgtccc    180
caccgatgaa atgggaaggg gtggtggggg ggtgaggggg cagtgctcag ctcaggcccc    240
actcccctgc cttgcctccc tccctgcctg ctgtgcancc tgggagcatg agacagagaa    300
gcagaggagc ctgggaagct tctcgaagga tggagggcgc ccacctcctg gaccccttgg    360
gtctccttgg cttccccacg gctgttggcg ctggtggaca ggacaggtga agacacaggc    420
agcctggggg cgggggccac accgctgctg gcctccacag gacccagcca cccagcaggc    480
atgggggacg caagtcttgc gcagggaagg aggacgctgg ccctgtgagg gcacgtgttg    540
gcgaatgcac gaagacgtgg catctgttgt gctcctctcc agccagggca gtgagcaggt    600
cygggttcag ttctcctggg gtgataagtc cagagcagac atcctcctcc agtgtgaggg    660
tgacgcttgg ccaggatgca caggcccatc tgaagcccac tgaccgccgg gcgatggcca    720
tgacacagat gcttccagag agactgctgc ttcgagcagt gacagcagag gtggctgcaa    780
ggatgccgtg aagcccaggt ggggactgtc tcttggatcc acagrstggc tccgccagtg    840
gccccgagcc acctgcccag gcctacatgc cttggtctgg ccttggggct ggtcttgggt    900
ttgacatggt ggggtgcagc catgaatggg caaccggggt ctcaggcccc caggctgcct    960
gtgtcttcac ctgtccttgg cttccc                                         986

<210> 1112
<211> 439
<212> DNA
<213> Homo sapiens

<400> 1112
atccgcattc ccatttacgt gatgatcatc gcctcggtgg tcagcgctgt acagatgctg     60
atcaacgcct acgcctttgg cctgtatcaa tcattaggga tttttattcc gctgattgtc    120
actaactgta tcgttgtggg ccgcgctgaa gccttcgccg ccaaaaaagg tccggcgctt    180
tcggcactgg acggcttttc aattggtatg ggcgcaacct gcgccatgtt cgtgctgggt    240
tcactacgcg aaattatcgg caatggcaca ttgtttgacg gtgcagatgc gctgttaggt    300
agctgggcaa aagtattacg cgtggagatt ttccacaccg actccccttt cctgctggcg    360
atgctgccac cargtgcatt tattggcctg ggactgatgc tggcaggaaa atacctgatt    420
gatgaaagaa tgaaaagcg                                                 439

<210> 1113
<211> 1785
<212> DNA
<213> Homo sapiens

<400> 1113
ctgggcgggc ctgcgtcagg ttgcagtttc acttttagct ctgggcacct ccagctcctg     60
ctcgccggac ggctcccagg gagagcagac gcgccagacg cgccaccctc ggggcgccga    120
cggtcacgga gcatggggtc ggcctttgag cgggtagtcc ggagagtggt ccaggagctg    180
gaccatggtg gggagttcat ccctgtgacc agcctgcaga gctccactgg cttccagccc    240
tactgcctgg tggttaggaa gccctcaagc tcatggttct ggaaaccccg ttataagtgt    300
gtcaacctgt ctatcaagga catcctggag ccggatgccg cggaaccaga cgtgcagcgt    360
ggcaggagct tccacttcta cgatgccatg gatgggcaga tacagggcag cgtggagctg    420
gcagccccag gacaggcaaa gatcgcaggc ggggccgcgg tgtctgacag ctccagcacc    480
tcaatgaatg tgtactcgct gagtgtggac cctaacacct ggcagactct gctccatgag    540
aggcacctgc ggcagccaga acacaaagtc ctgcagcagc tgcgcagccg cggggacaac    600
gtgtacgtgg tgactgaggt gctgcagaca cagaaggagg tggaagtcac gcgcacccac    660
aagcgggagg gctcgggccg gttttccctg cccggagcca cgtgcttgca gggtgagggc    720
cagggccatc tgagccagaa gaagacggtc accatcccct caggcagcac cctcgcattc    780
cgggtggccc agctggttat tgactctgac ttggacgtcc ttctcttccc ggataagaag    840
cagaggacct tccagccacc cgcgacaggc cacaagcgtt ccacgagcga aggcgcctgg    900
ccacagctgc cctctggcct ctccatgatg aggtgcctcc acaacttcct gacagatggg    960
gtccctgcgg agggggcgtt cactgaagac ttccagggcc tacgggcaga ggtggagacc   1020
atctccaagg aactggagct tttggacaga gagctgtgcc agctgctgct ggagggcctg   1080
gagggggtgc tgcgggacca gctggccctg cgagccttgg aggaggcgct ggagcagggc   1140
cagagccttg ggccggtgga gcccctggac ggtccagcag gtgctgtcct ggagtgcctg   1200
gtgttgtcct ccggaatgct ggtgccggaa ctcgctatcc ctgttgtcta cctgctgggg   1260
gcactgacca tgctgagtga aacgcagcac aagctgctgg cggaggcgct ggagtcgcag   1320
accctgttgg ggccgctcga gctggtgggc agcctcttgg agcagagtgc cccgtggcag   1380
gagcgcagca ccatgtccct gccccccggg ctcctgggga acagctgggg cgaaggagca   1440
ccggcctggg tcttgctgga cgagtgtggc ctagagctgg gggaggacac tccccacgtg   1500
tgctgggagc cgcagcccag ggccgcatgt gtgcactcta cgcctccctg gcactgctat   1560
caggactgag ccaggagccc cactagcctg tgcccgggca tggcctggca gctctccagc   1620
agggcagagt gtttgcccac cagctgctag ccctaggaag gccaggagcc cagtagccat   1680
gtggccagtc taccatgggg cccaggagtt ggggaaacac aataaaggtg gcatacgaag   1740
gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                   1785

<210> 1114
<211> 1538
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (689)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1493)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1508)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1532)
<223> n equals a,t,g, or c

<400> 1114
atttcttatc agtgtaaccg tcagagaaaa cgtgctccag cccaaaaaaa cgttacaatt     60
gccgcccatt actgaaaacc acagtaaagc gaggttttat gcgtaccgtt ttgaacattc    120
tgaactttgt gcttggcgga tttgccacca ctctgggctg gctgttggcg actctggtca    180
gtattgtgct gatttttacc ttaccgctga cacgatcctg ctgggagatc actaaactgt    240
ctctggtgcc ttatggcaat gaagctattc atgtcgatga actgaacccg gctggcaaaa    300
atgtgctgct gaatactggc ggtacggtat tgaatatttt ctggctgatt ttctttggct    360
ggtggttatg cctgatgcac attgcaacgg gcatcgcaca atgtatttca atcattggca    420
ttcctgtcgg cattgcgaac tttaaaattg ccgctattgc actatggccg gttggtcgtc    480
gcgtggtatc ggtagaaaca gcgcaagcgc gcgtgaagcc aatgcacgtc gtcgttttga    540
ataatccact aatatggcct ttatgctaag tcctttgctc aaacgctata cctggaacag    600
cgcctggctg tattacgcgc gtatttttat tgcgctttgt ggaaccacag cgtttccgtg    660
gtggctgggt gatgtaaaac tgacgattnc ctaacgctgg ggatggtggc agcggcgctg    720
accgatctcg atgaccgact ggcgggacgt ttgcgtaacc tcatcattac gctgttctgc    780
ttttttatcg cctcggcctc agtagaattg ctgtttccct ggccctggct atttgcgatt    840
ggcttaacgc tctctaccag cggcttcatt ttgctcggcg gtctgggtca acgctatgca    900
acaattgcct tcggtgcatt gctgatcgcc atttacacta tgttgggaac atcactgtat    960
gagcactggt atcagcagcc gatgtatctg ctggccggtg ccgtctggta caacgtcctg   1020
acacttattg gtcatctgct gttcccggtc cgcccgctgc aggacaacct ggcgcgttgc   1080
tatgaacaac tggcgcgtta tcttgagctc aagtcgcgca tgtttgatcc tgatattgaa   1140
gatcaaagcc aggcaccgct gtacgatttg gctctcgcca acggtctgct gatggcgaca   1200
ttgaatcaga cgaaactctc gctgctgacc cgcttacgtg gcgatcgtgg tcaacgggga   1260
acgcgtcgca cgctggcatt attactttgt cgcacaggat attcacgagc gtgccagctc   1320
ttctcatatt cagtatcaaa cattgcgtga acattttcgc cacagcgacg tgctgttccg   1380
ttttcagcgg ctgatgtcga tgcagggcca ggcgtgccag caactgtcac ggtgtatttt   1440
gttgcgtcag ctttattcaa catgatccgc atttttgagc gcgcttttta cgnatattga   1500
tgctgcgntg gagcggatgc gcgattaacg gnggaacc                           1538

<210> 1115
<211> 704
<212> DNA
<213> Homo sapiens

<400> 1115
ccgctggacc ctgggcctgg cctggcccca ctgggggcta tgggctgggc tcaccctctc     60
ctctgcgggg gtggagggcc accagccttg gctgttacaa tcttacaccg gacagtattg    120
ggctccctcc ctctccccar ggccccacgt tctgcagcct taaggttgaa catgagtgca    180
cgtccatgtc agtgctgtgg gactcctgtg cgtgcctcgg actgcgtgtg tcggcgggac    240
gcaggcacac gtgggtgtgt gtgcatgtgt gtttgtgtga gggcagcgtg tcctccagtg    300
tgcatggtgt gtgggcttgg gccccatccc tggcccgagc atttcatcct gtgggggagg    360
ggtgctgacc tagtgggagg agccccactg tgatccatga gctgccctgc ccacgcctcc    420
cctccctgta gcaacacctc tgggtgtttg gagtttagct tttgtgggtt tgctctccct    480
atcccatctc ctgtactaca cagttcatgg cagggtgggg aggggtgggg ttggttcggg    540
tgggtgaggg tctttttcct ctgtgtgcga tgttgttatc tgacagttct ccgtccctac    600
tggcctttct cctcgtcttc atatttgtac ggtacaagca ataaagacac tcatttcaga    660
aaaaaaaaaa aaaaaaaaaa aattctcggc cgcaagggaa ttca                     704

<210> 1116
<211> 1625
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1619)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1624)
<223> n equals a,t,g, or c

<400> 1116
tgtctacacc tttggcacct gcattgcctt cctaatcatc attggcgacc agcaggacaa     60
gattatagct gtgatggcga aagagccgga gggggccagc ggcccttggt tacacagacc    120
gcaagttcac catcagcctc actgccttcc tcttcatcct gcccctctcc atccccaggg    180
agattggttt ccagaaatat gccagcttcc tgagcgtcgt gggtacctgg tacgtcacag    240
ccatcgttat catcaagtac atctggccag ataaagagat gaccccaggg aacatcctga    300
ccaggccggc ttcctggatg gctgtgttca atgccatgcc caccatctgc ttcggatttc    360
agtgccacgt cagcagtgtg cccgtcttca acagcatgca gcagcctgaa gtgaagacct    420
ggggtggagt ggtgacagct gccatggtca tagccctcgc tgtctacatg gggacaggca    480
tctgtggctt cctgaccttt ggagctgctg tggatcctga cgtgctcctg tcctatccct    540
cggaggacat ggccgtggcc gttgcccgag ccttcatcat cctgagcgtg ctcacctcct    600
accctatcct gcacttctgt gggcgggcgg tggtggaagg cctgtgctgc sctaccaggg    660
ggtgccagtg gaggaggacg tggggcggga gcggcggcgg cgagtgctgc agacgctggt    720
ctggttcctg ctcaccctgc tgtggcgctc ttcatccctg acatcggcaa ggtgatctca    780
gtcattggag gcctggccgc ctgcttcatc ttcgtcttcc cagggctgtg ctcattcaag    840
ccaaactctc tgagatggaa gaggtcaaac cagccagctg gtgggtgctg gtcagctacg    900
gagtcctctt ggtcaccctg ggagccttca tcttcggcca gaccacagcc aacgccatct    960
ttgtggatct cttggcataa ccactgcctc ccagggaaca caaggccttt gccattggtc   1020
gcaggaaccc atctcttaga gctatggggc cattcttagt ccacgatcat tccaactggt   1080
gggatgacat ccggacatcc tcttccaggg actggggcaa actcaggccc cacacctctg   1140
gacagctcaa atccagtccc cttcctgctc cccagtcctg gcagtgccgt ggatggcggc   1200
aggaagtctc acatcataga ggacccctcc tcctctccca gttctcaact tctccatgcc   1260
tggaatccac gggtgaagag agtcggtaga tctcataaga aagaatccag tctgacttcc   1320
ctctggagaa tgactatgga cagaaggcca ccatcctcca cagagcaccc tgtcctgagt   1380
aggggttgtg ctcattaccc caggccagtg gtagcttcct caggagcctg gccacttcca   1440
acggtagcac tgaagtcatg caaatgcata gtcaggtaga ttcagacctt gtccacacct   1500
tyytgggcaa cccccaccat gaacctgtca gcctctttcc catagctaat agacatttcc   1560
caggccttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaana   1620
aaana                                                               1625

<210> 1117
<211> 2612
<212> DNA
<213> Homo sapiens

<400> 1117
attgacaaga gctatctaga aaacttgcag tcggattcgt ctattgtcac catggctttc     60
ccaactctcc aagccatcct tgctcaggat atccaggaaa ataactttgc agagagctta    120
gtgatgacaa ccactgtcag ccacaatacg actatgccat tcaggatttc aatgactttt    180
aagaacaata gcccttcagg cggcgaaacg aatgygtctt ctggaacttc aggcttgcca    240
acaacacagg ggggtgggac agcagtgggt gctatgttga agaaggtgat ggggacaatg    300
tcacctgtat ctgtgaccac ctaacatcat tctccatcct catgtcccct gactccccag    360
atcctagttc tctcctggga atactcctgg atattatttc ttatgttggg gtgggctttt    420
ccatcttgag cttggcagcc tgtctagttg tggaagctgt ggtgtggaaa tcggtgacca    480
agaatcggac ttcttatatg cgccacacct gcatagtgaa tatcgctgcc tcccttctgg    540
tcgccaacac ctggttcatt gtggtcgctg ccatccagga caatcgctac atactctgca    600
agacagcctg tgtggctgcc amcttcttca tccacttctt ctacctcagc gtcttcttct    660
ggatgctgac actggggcct catgctgttc tatcgcctgg ttttcattct gcatgaaaca    720
agcaggtcca ctcagaaagc cattgccttc tgtcttggmt atggctgccc acttgccatc    780
tcggtcatca cgctgggagc cacccagccc cgggaagtct atacgaggaa gaatgtctgt    840
tggctcaact gggaggacac caaggccctg ctggctttcg ccatcccagc actgatcatt    900
gtggtggtga acataaccat cactattgtg gtcatcacca agatcctgag gccttccatt    960
ggagacaagc catgcaagca ggagaagagc agcctgtttc agatcagcaa gagcattggg   1020
gtcctcacac cactcttggg cctcacttgg ggttttggtc tcaccactgt gttcccaggg   1080
accaaccttg tgttccatat catatttgcc atcctcaatg tcttccaggg attattcatt   1140
ttactctttg gatgcctctg ggatctgaag gtacaggaag ctttgctgaa taagttttca   1200
ttgtcgagat ggtcttcaca gcactcaaag tcaacatccc tgggttcatc cacacctgtg   1260
ttttctatga gttctccaat atcaaggaga tttaacaatt tgtttggtaa aacaggaacg   1320
tataatgttt ccaccccaga agcaaccagc tcatccctgg aaaactcatc cagtgcttct   1380
tcgttgctca actaagaaca ggataatcca acctacgtga cctcccgggg acagtggctg   1440
tgcttttaaa aagagatgct tgcaaagcaa tggggaacgt gttctcgggg caggtttccg   1500
ggagcagatg ccaaaaagac tttttcatag agaagaggct ttcttttgta aagacagaat   1560
aaaaataatt gttatgtttc tgtttgttcc ctccccctcc cccttgtgtg ataccacatg   1620
tgtatagtat ttaagtgaaa ctcaagccct caaggcccaa cttctctgtc tatattgtaa   1680
tatagaattt cgaagagaca ttttcacttt ttacacattg ggcacaaaga taagctttga   1740
ttaaagtagt aagtaaaagg ctacctagga aatacttcag tgaattctaa gaaggaagga   1800
aggaaggaag gaaggaaaga agggagggaa acagggagaa agggaaaaag aagaaaaaga   1860
gaaagatgaa aataggaaca aataaagaca aacaacatta agggccatat tgtaagattt   1920
ccatgttaat gatctaatat aatcactcag tgcaacattg agaatttttt tttaatggct   1980
caaaaatgga aactgaaagc aagtcatggg gaatgaatac tttgggcagt atcttcctga   2040
tgtcttctta gctaagagga ggaaaaaaag gctgaaaaaa tagggaggaa attccttcat   2100
cagaacgact tcaagtggat aacaatattt ataagaaatg aatggaagga aatatgatcc   2160
tcctgagact aactttgtat gttaaggttt gaactaagtg aatgtatctg cagaggaagt   2220
attayaaaga tatgtcatta gatccaagtg ctgattaaat ttttatagtt tatcagaaaa   2280
gccttatatt ttagtttgtt ccacattttg aaagcaaaaa atatatattt gatataccct   2340
tcaattgcca aatttgatat gttgcactga agacagaccc tgtcatatat ttaatggctt   2400
caagcaggta cttctctgtg cattatagaa tagattttaa taatcttata gcattgtata   2460
ttattattgc tgttgtcact gttattatta ttgtggatac tggcccttgg tgtgttgcat   2520
agctccctat gtattctctg tttccatctt taagttccca gaccaatata cattaagagt   2580
tttgaaaaaa aaaaaaaaaa aaaaactcgt ag                                 2612

<210> 1118
<211> 641
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (625)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (641)
<223> n equals a,t,g, or c

<400> 1118
tttttttttt aagggcagta aatacatttg ttcaaagtta taaaacaacg gcattccgtt     60
ctaactggga ctatttacag tgggagatgg tacatactgt tgaggctgta gtgggaggaa    120
gaggtgggcc accgctggac actcttgggc cgaggggcaa gggtggacat agcattggca    180
tggcagcaag agacttggct gagggcaggg gtggaaggat gtctactgct gaagaccaaa    240
tcccttgcca ctctgtcggt tgctactaag tcaaacgcaa acagaaacag gaaaagacag    300
caggagcaca gaggccagca tctccctttc cttatgccat ggagccaggt gccaggcgtg    360
ggctggtcca tctccctcct cagcctctgc caaagggctg ctccagtgct cccctcagtg    420
gaactcctca gccaggcgct ctgaaaccaa ccacagtcca ctgaagttga ccaccctacc    480
gagacagacc aaggctcaca ggtgaaaacc cctttcaaca aaattccttc caggtaggaa    540
tcagaatatg atgcgtttyc catctgccgg gttctgctcc atgggacagt assgacactt    600
cagctttcct ccattaatga gcttnttgag tgcatctcgg n                        641

<210> 1119
<211> 2242
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1748)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2226)
<223> n equals a,t,g, or c

<400> 1119
ttgggcttgg gagccggcag gtgcgggccg agggcgggca cagcggccgg cggagctgag     60
gcgcgcggcg gggaaagctc ggccggcctc ccgggcccca gccttctcca gaacccctgc    120
tacccacgac taagccccga acaatctgcc cttgggcttg ttctcttcgc agttgtcggc    180
cctgggccgg gagctggagt cccagactca taggtcccgg cccagccccc gaagagccgc    240
ctcagccggg gggagttgct cggactcaaa cgtccagtcc tcgtgcgacc gcgctgggtc    300
ggaagtgagc aggctgaggc caccatggag cagtgtgcgt gcgtggagag agagctggac    360
aaggtcctgc agaagttcct gacctacggg cagcactgtg agcggagcct ggaggagctg    420
ctgcactacg tgggccagct gcgggctgag ctggccagcg caggtgggtg gccacccttg    480
caagtgccct gcgacacctc cctgaggaca tgggagaccc gaagctactg agtgacaggg    540
ttccggaaga cgatgatgag gatgttggta cctgcatctg taggcctcct tgaaaccggc    600
cctccaggga ccctctctca gccaccctct ctctggtgat gtcacagtgc tgccggaaga    660
tcaaagatac ggtgcagaaa ctggcttcgg accataagga cattcacagc agtgtatccc    720
gagtgggcaa agccattgac aggaacttcg actctgagat ctgtggtgtt gtgtcagatg    780
cggtgtggga cgcgcgggaa cagcagcagc agatcctgca gatggccatc gtggaacacc    840
tgtatcagca gggcatgctc agcgtggccg aggagctgtg ccaggaatca acgctgaatg    900
tggacttgga tttcaagcag cctttcctag agttgaatcg aatcctggaa gccctgcacg    960
aacaagacct gggtcctgcg ttggaatggg ccgtctccca caggcagcgc ctgctggaac   1020
tcaacagctc cctggagttc aagctgcacc gactgcactt catccgcctc ttggcaggag   1080
gccccgcgaa gcagctggag gccctcagct atgctcggca cttccagccc tttgctcggc   1140
tgcaccagcg ggagatccag gtgatgatgg gcagcctggt gtacctgcgg ctgggcttgg   1200
agaagtcacc ctactgccac ctgctggaca gcagccactg ggcagagatc tgtgagacct   1260
ttacccggga cgcctgttcc ctgctggggc tttctgtgga gtcccccctt agcgtcagct   1320
ttgcctctgg ctgtgtggcg ctgcctgtgt tgatgaacat caaggctgtg attgagcagc   1380
ggcagtgcac tggggtctgg aatcacaagg acgagttacc gattgagatt gaactaggca   1440
tgaagtgctg gtaccactcc gtgttcgctt gccccatcct ccgccagcag acgtcagatt   1500
ccaaccctcc catcaagctc atctgtggcc atgttatctc ccgagatgca ctcaataagc   1560
tcattaatgg aggaaagctg aagtgtccct actgtcccat ggagcagaac ccggcagatg   1620
ggaaacgcat catattctga ttcctacctg gaaggaattt tgttgaaagg ggttttcacc   1680
tgtgagcctt ggtctgtctc ggtagggtgg tcaacttcag tggactgtgg ttggtttcag   1740
agcgcctngc tgaggagttc cactgagggg agcactggag cagccctttg gcagaggctk   1800
aggagggagt tgctcggact caaacgtcca gtcctcgtgc gaccgcgctg ggtcggaagt   1860
gagcaggctg aggccaccat ggagcagtgt gcgtgcgtgg agagagagct ggacaaggtc   1920
ctgctgtctt ttcctgtttc tgtttgcgtt tgacttagta gcaaccgaca gagtggcaag   1980
ggatttggtc ttcagcagta gacatccttc cacccctgcc ctcagccaag tctcttgctg   2040
ccatgccaat gctatgtcca cccttgcccc tcggcccaag agtgtccagc ggtggcccac   2100
ctcttcctcc cactacagcc tcaacagtat gtaccatctc ccactgtaaa tagtcccagt   2160
tagaacggaa tgccgttgtt ttataacttt gaacaaatgt atttactgcc cttctcattt   2220
ctcctngggc aacctttagg ct                                            2242

<210> 1120
<211> 3159
<212> DNA
<213> Homo sapiens

<400> 1120
aagaaagcga tcctgaccac cattggtgtg ctggaggagc ccctggggaa tgcccgtctg     60
catggcgccc gcctcatggc agcactgctg cacacaaaca cacccagcat caaccaggag    120
ctctgccggc tcaacacgat ggacttactg ctggacttgt tctttaagta cacctggaat    180
aactttttgc acttccaagt ggaactatgc atagccgcta ttctctccca cgctgcccgt    240
gaggagagga cagaagccag cggatccgag agcagggtgg agcctccgca tgagaacggg    300
aaccggagcc tggagactcc ccagccggcc gccagcctcc ctgacaacac aatggtgacc    360
cacctgttcc agaagtgctg cctggtgcag aggatcctgg aggcctggga agccaacgac    420
cacacgcagg cagcgggtgg catgagacgt gggaacatgg gccacctcac acggatcgcc    480
aacgcggtgg tgcagaacct ggagcggggc cctgtgcaga cgcacatcag cgaggtcatc    540
cgagggctcc ctgcggactg ccgtggccgc tgggagagct tcgtggagga gacgctgacg    600
gagacgaacc gcaggaacac tgtggacctg gccttctctg actaccagat ccagcagatg    660
acagccaact tcgtggatca gtttggcttc aatgatgagg agtttgccga ccaggacgac    720
aacatcaatg ccccgtttga caggatcgca gagatcaact tcaacatcga cgctgacgag    780
gacagtccca gcgcagctct gtttgaggcc tgctgcagtg accgcatcca gccctttgat    840
gatgatgagg acgaggacat ctgggaggac agtgacactc gctgtgctgc ccgggtgatg    900
gccagaccca ggtttggagc cccccatgct tcagagagtt gctcaaagaa tggcccagag    960
cgtggaggcc aggatgggaa ggcgagcttg gaagcacaca gagatgcacc tggggcaggt   1020
gccccaccgg cccccgggaa gaaggaagcc ccccctgtgg agggtgactc agaaggcgcc   1080
atgtggacgg cagtgtttga tgagccagcg aactcaacgc ccacagcccc aggagtggtg   1140
arggacgtgg gttccagtgt gtgggcagct ggcacctcag ctccagagga gaaaggctgg   1200
gccaagttca ctgacttcca acctttctgc tgctccgagt cagggcccag gtgcagctct   1260
ccggtggaca cagaatgcag ccatgctgag ggcagccgga gccaaggccc tgagaaagcc   1320
ttcagcccgg cttctccatg tgcctggaac gtgtgtgtca ccaggaaggc ccccctgctg   1380
gcctctgaca gtagctcctc tgggggctcc cacagcgagg atggcgacca gaaggcagcg   1440
agtgccatgg atgcggtgag caggggtccc ggccgggagg cccccccgct gcccacagtg   1500
gccaggacag aggaggckgt cggcagggtc gggtgtgctg acagccggct gttaagccct   1560
gcctgccccg cgccaaagga agtgactgct gccccagccg tggctgtgcc ccccgaggct   1620
actgtggcca tcaccacagc actgagcaag gctggccccg ccatacccac cccagcagtc   1680
tcttctgcac tggccgtggc ggtcccccta gggcccatca tggcagtcac agcagcccca   1740
gccatggtgg ccaccctggg gacagtgaca aaggacggga agacagatgc cccgccagaa   1800
ggagctgcct taaatggccc agtgtgatgc tgctgccgcc cgccacggcc caccctggtc   1860
aggctgcctc cttaatcgag aaaactacct ggtgatgcaa tctttttttt ttttaattta   1920
atttaatttt aaaataaatg ctgcattggt aaagctggca gttgaaacca gttggacggc   1980
ccagcttgcg tctcttctgc ctgagtgggc ctctcaggtc actcgtgccc tgctggagga   2040
cagaggggca cctcagccgc ccccaagccc agagcacagc aataaggtcg gcctgcagga   2100
gccggggtgg gggtgggggt ggggggggca ggaccctgag atgccaccag gacctgatgg   2160
gccaggaagg gcgtggacat ggaggctgtt tttacagttt tttttttgtt gttgttttgt   2220
ttttaaagaa tacagaagga gccaagcttt tttgcacttt gtatccagct gcaagctcag   2280
ggcagagtca agggcctggg ttggaaaaac ctgactcaca ggaatgcata attgaccctt   2340
gcagctaccc aatagccctt ggagctggca ctgaaccagg ctgcaagatt tgactgcctt   2400
aaaaacacaa ggccctctag gcctggcagg gatgtccctg tgcccagcac tgggggctcg   2460
aagactggtt tctagcacta ccggtcacgg ccatgtcgtc ctagaagggt ccagaagatt   2520
attttacgtt gagtccattt ttaatgttct gatcacctga cagggcaccc caaaccccca   2580
actcccaata aaagccgtga cgttcggaca aaccgcgtac tgtgaacctt ccggccccaa   2640
agccccggcc cggccaggkg tgggagagtc tcctccagca cctcttttgt gggcccgcca   2700
ccccccagcg ttatccccgt gtaatgggtg gaggcggaac aggccacatc acggcatcag   2760
gtctctacag cttagcaaat actgacattt ttccgtttgg gggatggggg gaaccacttc   2820
gcctaacgct caaacacatc aaccccagga cttccttttg tgccagctcc ccctcccaga   2880
agcctgggcc ccaccttgtc ctcagtggct gagtgggagg ggcaggtgga gaccagaccc   2940
ccaccccgcc ccagcgagct tgtctttcca ccacggttgg gggtggaggg aacccgctca   3000
gctccccaga ggccgagtct ctgccccagc tacacattga gtgccttgtt ctcaccgcct   3060
accctgtgcc tggcattygt cctctccccc cacagacgtg gaacagggag ggcagggtcc   3120
tttctcccct tactctgacc tgtgggtttt ccctgtgcc                          3159

<210> 1121
<211> 962
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (895)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (910)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (919)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (952)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (954)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (960)
<223> n equals a,t,g, or c

<400> 1121
tggttacggg gtcgggcaaa gggcagaggt caccgtccag gttggacagc agcacctttg     60
agcgatggcg gcgtctgggg aaccccagag gcagtggcaa gaggaggtgg cggcggtggt    120
agtggtgggc tcctgcatga ccgacctggt cagtcttact tctcgtttgc caaaaactgg    180
agaaaccatc catggacata agttttttat tggctttgga gggaaaggtg ccaaccagtg    240
tgtccaagct gctcggcttg gagcaatgac gtccatggtg tgtaaggttg gcaaagattc    300
ttttggcaat gattatatag aaaacttaaa acagaatgat atttctacag aatttacata    360
tcagactaaa gatgctgcta caggaactgc ttctataatt gtcaataatg aaggccagaa    420
tatcattgtc atagtggctg gagcaaattt acttttgaat acggaggatc tgagggcagc    480
agccaatgtc attagcagag ccaaagtcat ggtctgccag ctcgaaataa ctccagcaac    540
ttctttggaa gccctaacaa tggcccgcag gagtggagtg aaaaccttgt tcaatccagc    600
ccctgccatt gctgacctgg atccccagtt ctacaccctc tcagatgtgt tctgctgcaa    660
tgaaagtgag gctgagattt taactggcct yacggtgggc arcgctkcag atgctgggga    720
ggctgcatta gtgctcttga aaaggggctg ccaggtggta atcattacct taggggctga    780
aggatgtgtg gtgctgtcac agacagaacc tgagccaaag cacattccca cagagaaagt    840
caaggctgtg gataccacgg gtgctggtga cagctttgtg ggaactctgg ccttntactg    900
gcttactatn caaatctgnc ttggaagaca tgctcacaga tccaattcat tnancagcan    960
tg                                                                   962

<210> 1122
<211> 1764
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (618)
<223> n equals a,t,g, or c

<400> 1122
gcgcactgta ccgcgagtct gagatactta cagagagcta caatggaaaa gtcctggatg     60
ctgtggract ttgttgaaag atggctaata gccttggctt catggtcttg ggctctctgc    120
cgtatttctc ttttaccttt aatagtgact tttcatctgt atggaggcat tatcttactt    180
ttgttaatat tcatatcaat agcaggtatt ctgtataaat tccaggatgt attgctttat    240
tttccagaac agccatcctc ttcacgtctt tatgttccca tgcccactgg cattccacat    300
gaaaacattt tcatcagaac caaagatgga atacgtctga atcttatttt gatacgatac    360
actggagaca attcacccta ttccccaact ataatttatt ttcatgggaa tgcaggcaac    420
ataggtcaca ggttgccaaa tgcattactt atgttggtta acctcaaagt taaccttttg    480
ctggttgatt atcgaggata tggaaaaagt gaaggagaag caagtgaaga aggactctac    540
ttagattctg aagctgtgtt agactacgtg atgactagac ctgaccttga taaaacaaaa    600
atttttcttt ttggccgntc cttgggtgga gcagtggcta ttcatttggc ttctgaaaat    660
tcacatagga tttcagccat tatggtggag aacacatttt taagcatacc acatatggcc    720
agcactttat tttcattctt tccgatgcgt taccttcctt tatggtgcta caaaaataaa    780
tttttgtcct acagaaaaat ctctcagtgt agaatgcctt cacttttcat ctctggactc    840
tcagatcaat taattccacc agtaatgatg aaacaacttt atgaactctc cccatctcgg    900
actaagagat tagccatttt tccagatggg actcacaatg acacatggca gtgccaaggc    960
tatttcactg cacttgaaca gttcatcaaa gaagtcgtaa agagccattc tcctgaagaa   1020
atggcaaaaa cttcatctaa tgtaacaatt atataatgtt tccctttttg attattgcat   1080
tgtattttaa tttgtgcaga atgataaaga atgttccttt tagaagtgtg ttatgtctgt   1140
acctgtctga agagtgacat taaactttga aaggacttca ctgctccttt acgatattcc   1200
aaatagtttt ttacattgga aaaactaatt cttgggattc tttcatacat tttcatcaaa   1260
actttcagtg tgattatgta ttcatatctt cagtttaata tgtcagtata atagatattg   1320
ttcaaaagtt tcttgttgct aaagtggtgt aatctgttac acagatgaat agctagatgt   1380
ggaaagagat atgtaaacaa gaaacctttg ggtattgttt cttaagtaaa tattgggaca   1440
atcatggtaa gcaaacttag ttctgtaact gcatttttca ccttaaaagt taaatgaaat   1500
gcatgatggt attttattcc ttgaattatg caatgcaaca ttttacatgt aaatagcact   1560
ggtcatatac tgatgtatat ggttatctgg gttatatcta tttttatgta aactctattt   1620
tgtttttggc aagaagtgaa attgagactt atgtgcaggt tgccattgaa ttttgctctg   1680
gtgaatgctg agatccagct ttttcttaca aataaatggg accctgtttt ccaataaaaa   1740
aaaaaaaaaa aaaaaaaaaa aaaa                                          1764

<210> 1123
<211> 801
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (660)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (744)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (762)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (773)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (791)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (801)
<223> n equals a,t,g, or c

<400> 1123
cgggggtcat cttcttcctg gccctgctgc tgtgcattgc gcttctktcg tcctactcca     60
tccacctcct gctgacctgt gctggtattg cagggactgg ttcttgaagg gaaacctcct    120
catcatcatc gtcagtgtgt taatcatcct gcccctcgcc ctcatgaaac acttgggcta    180
cctggggtac accagtggtc tctctctgac ctgcatgctg tttttccttg tttcggtcat    240
ctacaagaag ttccaacttg gctgtgctat aggccacaat gaaacagcaa tggagagtga    300
agctctcgtg ggactcccca gccaaggact caacagcagc tgtgaggccc agatgttcac    360
agttgactca cagatgtcct acacagtgcc cattatggct tttgcttttg tctgccaccc    420
tgaggtgctg cccatctata cggagctctg ccgttccacg acctctacac ctcaggccct    480
ccaagcgcag gatgcaggcc gtggccaacg tgtccattgg ggccatgttc tgcatgtatg    540
ggctcacagc aacctttgga tacctcacct tctacagcag tgtgaaggcg gagatgctgc    600
acatgtacag ccagaaggac ccgctcatcc tctgtgtgcg cctggccgtg ctgcttcgcn    660
ggtgacccct cactgtgcca gtcgtgctgg ttcctatccg ccgggccctg gaagcaactg    720
cttttcccag gcaagggcct ttancttggc cacgacattg tnggccatta gcntttgaat    780
ccttgctttg ntttgggtca n                                              801

<210> 1124
<211> 1059
<212> DNA
<213> Homo sapiens

<400> 1124
tcgatacgac tttttttttt tttttttttt ttttttttcc gcagtgaaaa catttatttt     60
acaacagtaa tctttatttt aggccaacat tcagacatac aagacggaga tcaccatgcg    120
gaaccagcct ggcccttaga tgtgtgtgct cgagccagga tcagccggag tctgacagcg    180
cctgcacccc aacacggtcg gattccagga cgccagtgac aaaaccagtg catggacaag    240
cagcttccat gcgtgtgcat ttgattttta aaaacaatac atatttcagt gttaacttcc    300
cccctcacct ggcttgaaac attttcccca ttttccaggg aaacaaactc taccaaaagg    360
tgccgcctgc aggaccccgg gcccagcccc ttctggaggt ggtgctgtgt ggactcctct    420
ggggcggacc cggggccagc acagggcccc ttcccaggcc gcccttcaga tgcagctttg    480
ccactgaccg tatctgctgc tcagaaaatc agctttcatg tttcaaggca gggaagggct    540
tccagtcccc tcctcgattt cacaccggga cacacacctg ggtcaggtga gcatgacaca    600
cagcccccag gatgggcacc ccaccctgca gagcagaggc caatgctggt gggggccgtg    660
gcagtgccct gggcacacac cctctgcaca cagtgggctc agcgcttcct tctgtgcacc    720
tgctgggaaa gcctcctgca ggtccctgcc cgactcccaa gaaaccagag gccatttcag    780
agccaccttt aattgtactt gtcacttcac caggggacag cagcatgaat gacactcctg    840
ctgcgtgata tatacatata cacatatgta cacacacgga cacaccacag cccacactca    900
cagcatgtra cgacgcaaac tgttgctggt aaggacagta aaaatgtagc ttttgccaat    960
tccacaggag aatgatttac aaccaaaata acagacacag gccagtcctg cgccacaggg   1020
gttcacagct ctgaatactg ggaaagggtg agatcagct                          1059

<210> 1125
<211> 1542
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1449)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1490)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1500)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1520)
<223> n equals a,t,g, or c

<400> 1125
tcgacccacg cgtccgccgc tgtgctctcg acccctcctc ctgtagagag tggtgctgcc     60
ctctcgggat gtacctgcag gtggagaccc gcaccagctc ccgcctccat ctgaagaggg    120
ctccaggcat ccggtcctgg tccctgctgg ttggaatctt gtcgattggc ctggctgctg    180
cctactacag cggagatagc ctgggctgga agctcttcta cgtcacaggc tgcctgtttg    240
tggctgtgca gaacttggag gactgggagg aagccatctt cgacaagagc acagggaagg    300
ttgttttgaa gacgttcagc ctctacaaga agctgctgac tcttttcaga gctggccacg    360
accaggtggt ggtcctgctc catgatgtcc gtgatgtgag cgtggaggag gagaaggtcc    420
ggtacttcgg gaaaggctac atggtggtgc tccggcttgc gacgggcttc tcccaccccc    480
tcacgcagag tgcagtcatg ggccaccgca gtgatgtgga agccatcgcc aagctcatca    540
ccagcttcct ggagctgcac tgccttgaga gccccacaga gctgtctcag agcagcgaca    600
gtgaggccgg tgaccctgca agccagagct gacagcccca ctgtgcctga gcccgtgcac    660
cgyccacagg acccrtggca cattcccggt gtgcctgagc ccgtgcaccg cccacaggac    720
ccgtggcaca ttcccggtgt gcctgagccc gtgcaccgcc cacaggaccc gtggcacatt    780
cccggtgtgc ctgagcccgt gcaccgccca caggacccgt ggccttggct tcagttggtg    840
cctccagccg agttggccta ttgcctgctc atgctgctgc ttgcacactg catgaaacag    900
caggccagac caggacatcc agactttctc catcgtgagg cctgggcctg cctttctgca    960
gccggaggtc tcgccagccc tggactcctg ctttgggcca cagcaagacc tcgggcgagt   1020
ggagaggcgg ggccaggccg ggcccttgtg ggtgctgatg ctgcatgttg tccccgacac   1080
agcgtcctct ccctggtgga catccccagc ggtcaggtgc ttccccaagg gcagtgaggg   1140
gtgaacatcc agggcctacc tggctgtgca cgctgcagcc acactgtgga agctgcccct   1200
ccccgaggac ccgcctccct tgctgatgcc aggatctcgg cgcatagacc actctgcccc   1260
agcggtcgtc acagaaaggt ctctctgttc ctcacactca gcttcagcat aagctgtgag   1320
gccagaaaaa aggtcagctc ttctagtatc gtgcagtgct taaaaaccgg gagctccagc   1380
cgggcgcagt ggttcatgcc agtaatccca gcacttttcg gagggccgag gttgggagga   1440
tttgctttna gggccagggg gtttcaagga ccaggcctgg gggaaaacan aggcaaggtn   1500
cctgtttttt tgttaaaaan aaaattaaac ccaaaacagg ga                      1542

<210> 1126
<211> 586
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (567)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (578)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (584)
<223> n equals a,t,g, or c

<400> 1126
gttattcgcc ggaattatgc tgggctttat gcgtgctaac cacccgacct tcggttacat     60
tccgcaggtg cattaagcat ggtgaaagag ttcggcttga tggtgtttat ggcaggcgtt    120
ggtctgagcg ccggtagcgg tattaataac ggcctgggcg cgattggcgg tcagatgttg    180
attgccggat tgattgtcag tctggtgccc gtggttatct gtttcttgtt cggtgcttat    240
gtattgcgaa tgaaccgcgc gctgttgttc ggcgcaatga tgggcgcacg twcctscgcg    300
ccggcaatgg agatcatcag tgatacagct cgcagtaaca tcccggcgct gggctatgcg    360
ggcacctatg caatcgccaa cgtcctgytg acgytggcag ggacaatcat cgtcatggta    420
tggccaggat taggrtaaaa ctgaagttgc cctgcaaaat gaaatttttt tgcacaaccg    480
cagaactttt ccgcagggca tcagtcttaa ttagtggcca tgcttttctt tgaatgtccc    540
cattttgtgg aagcccatca accccgncat ttcgggtnca aggnag                   586

<210> 1127
<211> 1674
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1628)
<223> n equals a,t,g, or c

<400> 1127
actatagact tttacccttt atgacctttc aaaggtacct atagattgta aaattcagtt     60
ttccatctgt tacatagtat atactaggtc cataaatcca gtaaatctgt tttcatgatg    120
acctcatcca tcccatgatg tccacctatt tggcttaata ggacaatatg cctggaggac    180
caaccgtctg tgcagactgt ggcagaattt aagtgatggg tatgactaga acggtagcct    240
acctggatag gctgaacccc tcagtgatag tcccattacc tccattacaa gagagtctca    300
agcccaccat gcacacaatt taaaacaagg tccaaacctc agaagagggc aggctgacaa    360
ggctaaaagc ctctaggtgg tcttgttcca ggaataagcc aactaaaact tctccaatga    420
aggccaagtt gtagaggtga taggtggaga agctgratwa tctgnaagat agagagtcca    480
tttttccaaa acacacattc agtgtctgtc ctcccattca ctcaacctaa ctttccccaa    540
gttatagaac ttgaaatcag taatccacaa agcaaagaag caggctatag gattaacaca    600
ggtggcataa ttaaaataaa agaggggagg gagattttaa arcaatctgc cagagaaaaa    660
tgacaaatga tttggctttg tagctccttc tggcttgagc agttaggagc ctgagggctg    720
aggcagcagg ggcagcagga cctaaagatg acaagcaggc agagctcatc tgggccaggt    780
cactttcaag agctggggct gcaacacaga acatcaccac tggccctgag agcacattta    840
gctgtttttt gcaggaacca agggattgag acagtggcag aaccctcact ggagaaaaag    900
gaagatgaca graagccaca ctgacaaaga aaaattgcaa atacacaggc cacaatcata    960
accctaccat caaccctcaa ttttccaggg taataaccaa aggtaggctt attaacttgg   1020
ccctcagacc accccatcac cacgcagaga acaagaaact tatcaaaatc ctcctcccat   1080
gctttcccag tcctgcaaag aaataaaaag gagcagctaa gcacctgaaa gcaaagcagt   1140
gagcagaaag agaagcaagg gaaagagcca tggccccagt actccctgag attaccccag   1200
ttagcatcca caaataagaa ctcacggtca taagatcgaa tgcttttgca cgatggcaag   1260
agggaagagg acatctaggg caagatattc tgtcacaggc aagttcacat gaagccagtg   1320
aaggaggcag aagataaccc acctgacctc cacttgacta acacgtacac ctccccagtc   1380
gccttgcccc agtaggctcc caaatcgagt ctttaaagca ccttttccca aaagagcatc   1440
agtaagttct cccattatca tcccactcaa ccagtcttcc atttacccat cactaagccc   1500
aagcctccat tttgtccctg gttggaaatg tcatattttt tgccccagat cctcgatccc   1560
cagccctaca ataaaagcac agaagagtcc ttaattcccc acccaaccct agcatcccta   1620
tttggttngc ttgcacccca ccctttccca gattctatac ctttcactcg tgcc         1674

<210> 1128
<211> 846
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (751)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (803)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (816)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (827)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (846)
<223> n equals a,t,g, or c

<400> 1128
gnttgntacg ccagytcgaa attaaccctc actaaaggga acaaaagctg gagctccacc     60
gcggtggcgg ccgctctaga actagtggat cccccgggct gcaggaattc ggcacgagcc    120
tgtgtaagcc ctgtgtgaag ttttgacttt aatctaccag atcactcctt caccctccat    180
aaagatgtct gaacctgaca cttcctcagg attttcggga agtgtggaga atggaacttt    240
tcttgagctg tttcccacat ccctgtccac gtcagtggac ccatcctcag gccacctgtc    300
aaacgtctac atctatgtgt ccatattcct cagcctttta gcgtttctgc ttctgctttt    360
aatcattgcc ctccagaggc tcaaaaatat catctcctcc agttcctcct acccagagta    420
tccaagcgac gctggaagtt ctttcaccaa tttggaagtc tgcagcattt cctctcagag    480
gtccactttt tcaaaccttt catcctgagg aaaatggaag agtccttgag tgtggcagca    540
gttttgacat ccccttacgg aagtgtcccg tgaggcattg cctcatgaaa gaaatgatcc    600
ttttggtgta gacctgcttc tccttctcct ttttctctga tttcttttct gtcatgatgc    660
ttttcatttg gggatggaga caccgatgtt ggtggaaatg tgtgcaaacc ccaaggtgca    720
gaatttyaca caaatggctt gatgaatcta nactgggctt cttcaagtaa gtcaagttca    780
ttctactttt gttggacccc tanactcatc tgaggnggcc tttccgngga tgctggacat    840
ggactn                                                               846

<210> 1129
<211> 1222
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1198)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1199)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1219)
<223> n equals a,t,g, or c

<400> 1129
gcctgggttc ccascggctt csccagaggt ggaagaaacc cgaracgttc cgaagtcaac     60
gcaagcaaag gggagtgcgg gtcggggagg aatattcttt tggaaacgta atattggcct    120
tggggctctc cagccctttg ggacttccaa tgggatctta gaagcagccg aagcagcgtg    180
agggcggcas ccagggccag ccacgatttg aacgctctgc cttgcagctc ttctggaccg    240
aggagcccaa agccctaccc tcaccattca ccaggtcctg tgggaagagc agcgtggagr    300
tgggctgagg ttagaaggtg cagagcgtgg aagaagattg tgagctgagt attggacatc    360
tgttcttgaa tagtccctgg gcctgccata ggaaaggaag ttctccaggg ttacagttct    420
tatccgcgtg aatacacatg gctctgttac gaaaaattaa tcaggtgctg ctgttccttc    480
tgatcgtgac cctctgtgtg attctgtata agaaagttca taaggggact gtgcccaaga    540
atgacgcaga tgatgaatcc gagactcctg aagaactgga agaagagatt cctgtggtga    600
tttgtgctgc agcagggagg atgggtgcca ctatggctgc catcaatagc atctacagca    660
acactgacgc caacatcttg ttctatgtag tgggactccg gaatactctg actcgaatac    720
gaaaatggat tgaacattcc aaactgagag aaataaactt taaaatcgtg gaattcaacc    780
cgatggtcct caaagggaag atcagaccag actcatcgag gcctgaattg ctccagcctc    840
tgaactttgt tcgattttat ctccctctac ttatccacca acacgaagaa agtcatctat    900
ttggacgatg atgtaattgt acaaggtgat atccaagaac tgtatgacac caccttggcc    960
ctgggccacg cggcggcttt ctcagatgac tgcgatttgc cctctgctca ggacataaac   1020
agactcgtgg gacttcagaa cacatatatg ggctatctgg actaccggaa gaaggccatc   1080
aaggaccttg gcatcagccc cagcacctgc tctttcaatc ctggtgtgat tgttgcaaca   1140
tgacagaatg gaagcaccar cgcatcacca agcaattgga gaaaggatgc aaaagaanng   1200
gaggaaaacc tttttgcang tt                                            1222

<210> 1130
<211> 1179
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<400> 1130
tgttttcang caanctggat caatcactgt tccaatttct ctgaactccc cagagtattt     60
aacatatgcc caagtacaaa gaaatatcag tgctaacccc atgacaaggt tacacaagac    120
agctatagag tttaggccaa tgaagccagt cagtcctgag attatataca tagsaaacat    180
gaccgcaaac agtgtggctg gggtacgagc agcatagaag atatttttgc catyattgtg    240
ctttataaaa tttgsatagg tttcttcaat ttcagcttca agctggtcct gataacgacg    300
gcagaaytca tytccaccca tcttttttac tgaacgaaat tgttttatcg ccacttcctt    360
gagatccaag tgttttcgct ccagatctga aggtgcaatg taaggcttgt cccctccaca    420
tacctgttcc atacttttac aataggtatc tcttgctcct gctactgcag caagattatt    480
agcttcagct gttgcctgaa gcatggactt tggatgtgga agttcttctc cttgatagat    540
tttgatgtaa gccttaaaat attctacaag atctctacaa gtgactttag atccacttat    600
ctctttttct accaaatttt caggggcaag cagcaatgga accagatttc gaagctctcg    660
tttaaagtct tcatcaatat ctttcaatct cccatcaaaa ctaggattag ttgcaacttt    720
aagaccagga tgtggcaaaa ggaagcaacc aagatttgag aaacaattgt gtatgtgctt    780
ccttacattc tgaagctctt catgttgatt ttgttttacc tgtaatctct tttcaagaaa    840
ttgctttcca ccttccaaac catatgaatg ktcataagga tagctccaat ctcgaatcaa    900
aaacattaat gtctgaaatg gtttctggta gatttcttcc atcgcaagtc ttccatactc    960
tgtaaataat tgcaaatgtt gaagatcatc ttcttgaata ttctgagaca gattatatac   1020
ctggacagag ctagtcatag tgctcagagc aaacaccgtg cacagtcttt gatagttgac   1080
tggctatcaa aggcaccctg ggtatccata agcagcacag caactttagt tccattaggt   1140
ctgtcaatca caaatacttc attccaaact tgtatgccc                          1179

<210> 1131
<211> 1192
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1138)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1155)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1160)
<223> n equals a,t,g, or c

<400> 1131
aaaaaagaaa gaactctttg ggtgagggtt ggatgtgaga aatagtgaga tggctgggcc     60
aatgggttca gkgctgtagc ctcttaaatc ccagtaaact tataggtgtg tcacaaaaga    120
gttgggggga tttcttaaaa tgcacagtgc ccccttcata tgcagattgg ttatttatac    180
tctgtttcat tcaattttat gttcattcat tcatttagca atgtgtatcc aagcattcaa    240
acctctccca atccttcaaa gcttactcaa attctaccta tttcagaaag cttccttgcc    300
catcacagca tagcacctat ctgtgccttt watttcagga accacattct tctttgtcat    360
gcatctgtat tatcattggc ctcaatttct ttctggacac agaatccatg tcctaagcat    420
ctttgtatcc ctaaagccac cagaatagca ccatgtaaat agtatagcag gttctcagta    480
aataagaact gcatgaatga ataagttgga gggatggctg agtggcccta gatcaagcac    540
tattttctat attttctgag ctgaacaaag aagggagtgt agcaagttca attctggttt    600
agccatggag gttggtgggg tgagggaagc aatgagaagg taaagacgat tgctgagggc    660
agctatttgt gatcctgctg cttaaagata acactaaagg ctggatgtgc tggctcacac    720
ctgtgatccc atcactttgt ggaggtgaag caggaggact gcttgacccc agtagttcga    780
gaccaggttg gacaacataa acagacccag tatctacaaa aaacaaaaaa acgtagccag    840
tcactcacac ctgtaatacc agcattttgg aaggcagagg tgggtgagtc acttgggcac    900
agtttgagac cagcttgggc aacatggtga aatcccatct ctacaaaaaa tacaaaaact    960
agccgggtgt cgtagtacgc acctgtagtc ccagctactt gggaggctga ggtgggaaga   1020
tggcttgagc ccaggaagtc gargccacaa tgagccatga ttgtgctact ccactccagc   1080
ctgggcaaca garcaaaact ctgtctaaaa aawtaataag gctgaaccgc agtggctnca   1140
tgcctgttga tcccnaccan ttttggggaa aggctgaagt tgggttggat tc           1192

<210> 1132
<211> 1054
<212> DNA
<213> Homo sapiens

<400> 1132
agtcgggcgg tcttgtgcat cttggctacc tgtgggtcga agatgtcgga catcgagact     60
ggttcggagc atcccggcga tcacgcgcta ttggttcgcc gccaccgtcg ccgtgccctt    120
ggtcggcaaa ctcggcctca tcagcccggc ctacctcttc ctctggcccg aagccttcct    180
ttatcgcttt cagatttgga ggccaatcac tgccaccttt tatttccctg tgggtccagg    240
aactggattt ctttatttgg tcaatttata tttcttatat cagtattcta cgcgacttga    300
aacaggagct tttgatggga ggccagcaga ctatttattc atgctcctct ttaactggat    360
ttgcatcgtg attactggct tagcaatgga tatgcagttg ctgatgattc ctctgatcat    420
gtcagtactt tatgtctggg cccagctgaa cagagacatg attgtatcat tttggtttgg    480
aacacgattt aaggcctgct atttaccctg ggttatcctt ggattcaact atatcatcgg    540
aggctcggta atcaatgagc ttattggaaa tctggttgga catctttatt ttttcctaat    600
gttcagatac ccaatggact tgggaggaag aaattttcta tccacacctc agtttttgta    660
ccgctggctg cccagtagga gaggaggagt atcaggattt ggtgtgcccc ctgctagcat    720
gaggcgagct gctgatcaga atggcggagg cgggagacac aactggggcc agggctttcg    780
acttggagac cagtgaaggg gcggcctcgg gcagccgctc ctctcaagcc acatttcctc    840
ccagtgctgg gtgcrcttaa caactgcgtt ctggctaaca ctgttggacc tgacccacac    900
tgaatgtagt ctttcagtac gagacaaagt ttcttaaatc ccgaagaaaa atataagtgt    960
tccacaagtt tcacgattct cattcaagtc cttactgctg tgaagaacaa ataccaactg   1020
tgcaaattgc aaaactgaaa aaaaaaaaaa aaaa                               1054

<210> 1133
<211> 676
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (51)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (55)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (616)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (642)
<223> n equals a,t,g, or c

<400> 1133
cngtacgact cactataggg agagagctat gacgtcgcat gcacgcgtaa nttgnggccc     60
ctcgagggat cctctagagc ggccgccctt tttttttttt ttttactaat aacaagtata    120
ttttattaaa aacttcattt atcatgaaaa ttagtgagat tacgaagatt aaactataac    180
tgaatttcat accctaatgg gtcaagtccc tggtctagga gcattagaga ggactctctg    240
agcttctgca gcaacttcct tagctcttcc ttagaaaata ccaggtacag tttgtggcgc    300
tcagaggata ccatatctgc taactgtagg cattcctgat actgaccagt actgtgcaat    360
atcgtatgaa gcagaaaaca caacattggc agacaaagct ttctcagtaa gaccatttga    420
tgtgttcttt catggtcttc tttggcatcc tctctaacat ccaccatcca ccctccatca    480
acaaacaaca agacgttata cattttctcc ttcacatcag cagttagggc atccaaatgc    540
cctttccaaa taccaaaatc catttcatat ttcttttctt tgtgttcatg cggacsctgg    600
gtcgacccgg gaattncgga ccggtacctg caggcgtcct tntatagggc acctaaatag    660
cttttgcaaa agccta                                                    676

<210> 1134
<211> 1218
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (11)
<223> n equals a,t,g, or c

<400> 1134
nnnttagctt ncgcaaagct atttaggtga cactatagaa ggtacgcctg caggtaccgg     60
tccggaattc ccgggtcgac ccacgcgtcc gccagaggcc tgggcccagt gaactccccc    120
tctctgatta cccccttcgg gaggcatttg agctcctggg attagagaac ctggtgcagg    180
tgtttacctg tgttctttta gagatgcaaa tccttctcta ctcacaagat tatcaacgcc    240
tgatgactgt ggcagaaggc atcaccacac ttttgttccc atttcaatgg caacatgttt    300
atgtgcccat tctacctgct tctctgctac attttcttga tgctcctgtc ccttatctga    360
tgggccttca gtcaaaagaa ggaactgacc gttctaaact agaacttcct caagaggcta    420
atttgtgttt tgtggacatt gacaaccatt ttattgagtt gcctgaagaa tttccacagt    480
tccccaataa agtggatttt atccaagaac tctctgaggt tcttgttcaa tttgggatcc    540
ctcctgaggg cagcctacat tgcagtgaga gtaccagcaa actgaagaat atggttctga    600
aagacttggt caatgacaaa aagaacggca atgtctgtac taataacatc agcatgtatg    660
agttactgaa gggcaatgaa accatagccc gcttgcaggc tctggccaag cgtactggtg    720
tggctgtgga aaaaatggac ctctctgctt ctctgggtga aaaagacaag gatttaaaac    780
tgcattgtga agaggcagaa ctaagggact accagctcaa tgtacagctc cgagaggtct    840
ttgctaaccg ttttacacag atgtttgcag attacgaagc atttgtcatt cagactgccc    900
aggacatgga atcctggctg accaaccggg aacagatgca gaactttgac aaagtaaaaa    960
gaaccatagt tttccttttg tggttattag tggctttatt attgatttta acatttttaa   1020
attttttatt cttctgtgcc tatgcttacc catatattat tgattttgtt aacctttttt   1080
aaatgcagac tttttgtctt ccagccccat taagaacttt tctttaccaa gtatttttac   1140
attagataaa ataattttac aagcaaataa accagctcat tgaactggtm attaaattgt   1200
gcgttaaatt gcctgtaa                                                 1218

<210> 1135
<211> 1710
<212> DNA
<213> Homo sapiens

<400> 1135
gggccctcaa aaggaaatgt ttgtggggcc accaaaagca aatgtctctt gaacctagtc     60
acctgggggg acaagtgtgg gaaagtgcac ctgtgttccc atgagaccca ctcaagagga    120
gcagaaatcc tgttttgcta tttccttaat tgctactagg gctgggattt tttcatgttt    180
attggcccct ctacattttt ttctttaaaa aaattcacaa agcatgttta tatttgttag    240
ctcttttgat tctccctatg atagtgtgaa gacagggaca aaacgctacc atttcacact    300
cccagatcta acaatagcta ccaagtaatt atgccatgcg tttcttctaa ccttcgcaat    360
atcactacga ggtagttctt actatcctca ttttacagat aaggaaactg aggctaagtg    420
acgctggyag acttgcccaa ggccacacag ctggtaacag ggactggtag tcacttgagt    480
cctacatcag cacccttgct actacagcag ctcctcccct ttctagaggc ctagatggaa    540
agatgctggt gtcagcgggg ggcacaaagg tccacccagt cccacacatg cagagaggca    600
tcatttgttg ctgataacaa agtccttggt ctgcagggat gccaggtgtg ggtggtgacc    660
aaaggagcag ggtccatccc atttccatct aggaagatgt gacctctgtg agtgaagaga    720
ggttctactt ggctccgtgt tccatcttgg ctccgtgttc catcccaaga tgtggcatca    780
tagacctgga ctgtaccatc aaaacctgag atggccaagc aattcttcca gcctggggcc    840
caagtcacty gcagcagctc tgggtcaggg ctaggtacgg atactgggca ctggactgag    900
ctcacaggat ggcagagatc ccgggggtca agaagacaaa gacgcccatc tgagcaaggc    960
tggcaatgct gccccagccc tggccccagc tcccaacttc agcacaccat ctctctccac   1020
cagacccagg gccagggctg cgattctcca acggtgccca cttctgccgg gtgtcaacaa   1080
gccccagccg gccygaagca cagcagaagg caaaggtgtc tgcatctagg acctgcaggc   1140
tactcagctc ctcactgtca ctgacatctg aggtgtacgt ggtcttccgg gactccagat   1200
caacgacctg cagactkcgg agcctcgccc catggaggac tccgggtgcc aatgtggaga   1260
agacggccac cctaggccag agactctcct ctttctcatg cacagcaatg gtgctgacag   1320
ctttaatgac atcactgtcc tctgcaacct gccacacctg cagataacaa cctggaaggc   1380
cactggtaac cagcaatctg gtatgtggca catgctttag atcaaagata gacctgtctg   1440
aaaatcctcc atggcgcact ttgaaatctc tttctgggaa taagcccttg ttttccttta   1500
cagaaagtct gagaggtaat ttcagatgaa gaatttcatt ctttttcagg ctttcatagc   1560
cagcaacaaa gactcctttg tcatcaatcc attcaaggac tcgagtggct cctgacaggt   1620
cgaatgcata gaaatcctgg tacaagcgca aggattccac cagccagtcg tccccaggat   1680
ccatggcaac gaccgcttcc ggcgtctcac                                    1710

<210> 1136
<211> 975
<212> DNA
<213> Homo sapiens

<400> 1136
tttatttttt tttttttttt ttttttgcac ctaagacaat gttatttaat tgtaaaatct     60
ccaccccctg agcatatgtt ttcaggtctg ggtgactaat tagactggga aacaagggca    120
ggaacgatgg ccctgtgctt gctctgcccg ctgcctctgt ggatgtgtgg gccgctggct    180
tcagtcctgc ttttttgatg gccgttgttt acgctatgta tttttgcagg aggcctgagg    240
tgggctgggt tctcctccta tggcagggct tcactctcct cctccgttgg ggcttcgctg    300
tcccttgaga atccttcttc atcttcttgt aatgaccttc ggtgacaaca gatctcaatg    360
aggcagagaa gtataatcaa aatcgttagt attccagtca caattaacgc caagatgagt    420
tttttggtat agccatatcc tggaagttct tttgtgaact caagcgactt ctctttctgt    480
tcactctggg cttctgtgct ctcattaatg tagttctcag tcttccattg gtccgtatcc    540
cattctatct tggatgcctt tacttcctgc tgcccactga gaagcttcat caggtggcct    600
gtcctggaga cgagcttggc acaggtcact tgcacatggg ccccagagca gtccatcttc    660
aaggtccgga taacatgagc aatgagcctt ctcacattgt tgttggggat aasggactgy    720
agctgctggg ttagctgaat ttcaaactga tcacctgggg acgagagcaa tgggtaattg    780
aagcttttgg gctcggggga caggtcagtg cccacgttgt tgtattccca ttttgtctca    840
gtttgtttaa cagttggcyc taagttgaat gcagtccyag yggaatctgc ctcakgarga    900
tgattgtagt ttgtgttttc agagatggtk ccttctggca tgttagtgtt ttccataaaa    960
tccggacgcg tgggt                                                     975

<210> 1137
<211> 612
<212> DNA
<213> Homo sapiens

<400> 1137
cgctctagaa ctagtggatc ccccgggctg caggaattcg gcacgagcac catccagaac     60
cgagcagatc tcgtgataaa tgaagtgatg tggtgggacc atggagtgta ttactgcacc    120
attgaggctc caggggacac atcaggagac cccgataagg aagtaaagct catcgtccta    180
cactggctga cagtgatctt catcatcctg ggagccctcc tcctcctgct gctgattgga    240
gtgtgctggt gccagtgctg tcctcagtat tgctgctgct atatccgctg tccctgctgt    300
cctgcccact gctgctgtcc tgaggaagcc ctggcccgcc accgctacat gaagcaggcc    360
caggccctag gtcctcagat gatgggaaaa cccctgtact ggggggcgga caggagctcc    420
caggyttcat cttatccaat gcacccgctg ctgcagcgag atttgtccct gccgtccagc    480
ctcccgcaga tgccaatgac ccagaccacc aatcasccty ccatcgccaa tggtgtcctg    540
gagtatttgg agaaagaact gcggaacctc aacctggccc agcctctgcc ccctgacctc    600
aaaggcagat tc                                                        612

<210> 1138
<211> 1619
<212> DNA
<213> Homo sapiens

<400> 1138
gtggatcccc cgggctgcag gaattcggca cgagctttcc ttacctgttt ttccagctca     60
cccactgcca gcagagaatg ctgtccagtt tcaacgagtg gttttggcag gacaggttct    120
ggttaccacc caatgtcacg tggacagagc tagaagaccg ggatggccgt gtctaccccc    180
acccccagga cttgttggca gccctgcccc tggcgctggt cctcctggcc atgcgccttg    240
cctttgagag attcattggc ctgcccctga gccggtggct gggtgtgagg gatcagacca    300
ggaggcaagt gaagcccaac gccacgctgg agaaacactt cctcacggaa gggcacaggc    360
ccaaggagcc ccagctgtct ctcctggccg cccagtgtgg cctcacgctg cagcagaccc    420
agcgatggtt ccggagacgc cggaaccagg atcgacccca gctgaccaag aagttctgtg    480
aggccagctg gaggtttctc ttctacctgt cctccttcgt gggcggcctc tcggtcctgt    540
accacgagtc atggctgtgg gcaccagtaa tgtgctggga caggtaccca aaccagactc    600
tgaagccatc cctgtactgg tggtacctct tggagctggg tttctacctc tcactgctaa    660
tcaggctgcc ctttgatgtc aagcgcaagg atttcaagga gcaggtgata caccacttcg    720
tggcggtcat cctgatgacc ttctcctaca gtgccaacct gctgcgcatt ggctctctgg    780
tgctgctgtt acaygattcc tctgactacc tgctggaggc ctgtaagatg gtcaactaca    840
tgcagtatca gcaagtgtgc gacgctctct tcctcatctt ctcctttgtc ttcttctaca    900
cccgactggt cctctttccc acccagatcc tctacaccac atactacgag tccatcagca    960
acaggggccc cttcttcggc tactacttct tcaacgggct tctgatgttg ctgcagctgc   1020
tgcacgtgtt ctggtcttgc ctcattctgc gcatgctcta tagcttcatg aagaagggcc   1080
agatggagaa ggacattcgt agtgatgtag aagaatcaga ctccagtgag gaggcggcgg   1140
cggcccagga acctctgcag ctaaagaacg ggacagctgg agggcccagg ccagccccca   1200
ctgatggccc tcggagccgg gtggccgggc gtctgaccaa caggcacaca acagccacat   1260
agccgggcgg ggctggctgt aaggggttgc ccccccgcca gtgccttgga tatttctggg   1320
gtgactggac tggcgcccct gggccacctt tctggagaca gggagggccc cacccggggt   1380
gggtgggaag gctgatgatc tgtctccagc cccttccttc tgcccacccr cccttcttcc   1440
ctctgggcaa ctggacagat ctggsagcca gcagctggat gctgtggctg gccagagaca   1500
cctccaggct gtrgcctggg ggctgggggg agccccaggc tgaaaagggt ccaattaaaa   1560
caaatggagc caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaactcgag    1619

<210> 1139
<211> 1772
<212> DNA
<213> Homo sapiens

<400> 1139
tgtgaatgct tgagtaatac tgttattcct ctgctgcttc ctccaagaaa tatttttaac     60
aacaggttaa atttttcaga ccaaccaaat ctgactcagt ggattagaac aatatctcag    120
caaataaaag cattacagtt tcttaggaaa gaagaaagta ctcctaataa tgcctctaca    180
aagaattcag aaaatgtgga tgaattacag ctccctgaag ggttcaggcc tgattttcgt    240
cctaagatcc cttattctga gagcataaaa gaaatgctaa cgacatttgg aactgctacc    300
tacaaggtgg gactaaaggt tcatcccaat gaagargatc ctcgtgttcc cataatgtgt    360
tggggtagct gcgcgtacac catccaaagc atagaaagaa ttttgagtga tgaagataaa    420
ccattgtttg gtcctttacc ttgcagactg gatgactgtc ttaggtcatt gacgagattt    480
gccgcagcac actggacagt ggcatcagtt tcagtggtgc aaggacattt ttgtaaactt    540
tttgcatcac tggtgcctaa tgacagccat gaggaacttc catgcatatt agatattgac    600
atgtttcatt tattggtggg cttggtgctt gcatttcctg cgttgcagtg tcaggatttt    660
tcagggatca gccttggcac tggagacctt cacattttcc atctggttac tatggcacac    720
atcatacaga tcttacttac ctcatgtaca gaagagaatg gcatggatca agaaaatccc    780
ccttgtgaag aagaatcagc agttcttgct ttgtataaaa cacttcacca gtatacggga    840
agtgccttga aagaaatacc atccggctgg catctgtgga ggagtgtcag agctggaatc    900
atgcctttcc tgaagtgttc tgctttattt tttcattact taaatggagt tccttcccca    960
cccgacattc aagttcctgg aacaagccat tttgaacatt tatgtagcta tctttcccta   1020
ccaaacaacc tcatttgcct ttttcaagaa aatagtgaga taatgaattc actgattgaa   1080
agttggtgcc gtaacagtga agttaaaaga tatctagaag gtgaaagaga tgctataaga   1140
tatccaagag aatctaacaa attaataaac cttccagagg attacagcag cctcattaat   1200
caagcatcca atttctcgtg cccgaaatca ggtggtgata agagcagagc cccaactctg   1260
tgccttgtgt gcggatctct gctgtgctcc cagagttact gctgccagac tgaactggaa   1320
ggggaggatg taggagcctg cacagctcac acctactcct gtggctctgg agtgggcatc   1380
ttcctgagag tacgggaatg tcaggtgcta tttttagctg gcaaaaccaa aggctgtttt   1440
tattctcctc cttaccttga tgactatggg gagaccgacc agggactcag acggggaaat   1500
cctttacatt tatgcaaaga gcgattcaag aagattcaga agctctggca ccaacacagt   1560
gtcacagagg aaattggaca tgcacaggaa gccaatcaga cactggttgg cattgactgg   1620
caacatttat aattattgca ccaccaaaaa acacaaactt ggattttttt aacccagttg   1680
gctttttaag aaagaaagaa gttctgctga atttggaaat aaattcttta tttaaacttt   1740
maaaaaaaaa aaaaaaaaac tcgacggcac ga                                 1772

<210> 1140
<211> 1846
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1628)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1738)
<223> n equals a,t,g, or c

<400> 1140
gaaaggtgta agaaactagg aaacaatgcc ttgctgttga attctgtgat gtctgccttc     60
cgggctgagt tcatcgccac aaggtctatg gatttcattg gcatgattaa agagtgtgat    120
gaatctggtt tccccaagca tcttcttttt cgatcactgg gattaaactt ggccttggct    180
gatcctcctg agagtgaccg acttcagatt ctcaacgaag cttggaaagt catcactaag    240
ctgaagaacc cacaggacta cattaattgt gccgaagtgt gggtggaata cacctgcaag    300
catttcacga aacgagaggt gaataccgtt ttggcagatg tcatcaagca catgactcca    360
gatcgtgcat ttgaagattc ctacccccag cttcagttaa taattaagaa agttattgcc    420
cacttccatg acttctcagt tcttttctca gtggraaaat ttctgccgtt tctggacatg    480
ttccaaaaag agagtgtgcg ggtggaggtt tgcaaatgca tcatggacgc ctttatcaag    540
catcaacaag agcccaccaa ggacccggtc atcttgaatg cccttttgca tgtttgcaag    600
accatgcatg actctgtgaa tgcactcact cttgaggatg agaaaagaat gctgtcatat    660
ttgattaatg gatttataaa aatggtttcc tttggccgtg attttgaaca acagctgagt    720
ttttatgttg agtccaggtc gatgttttgc aatctggagc ctgttcttgt gcagttgatt    780
catagtgtga accggttggc aatggagaca agaaaagtaa tgaaaggaaa tcattccaga    840
aagacagctg catttgtccg ggcctgtgtt gcctactgct tcatcaccat cccctccctg    900
gcgggcatct tcacacgtct caatctctac ctgcattctg gtcaggtggc cttggccaac    960
cagtgcctct cccaagctga tgcttttttc aaagccgcta taagccttgt tccggaagtt   1020
ccaaagatga ttaatattga ygggaagatg cggccatcgg aatcgttcct tctggaattc   1080
ctctgcaatt tcttttctac tttattaata gttccggatc atcctgaaca tggggtcctg   1140
tttcttgttc gagagcttct caacgtgatc caggactaca cctgggagga caacagcgat   1200
gagaaaatcc gcatctacac ctgcgtcctg catctcctct ccgccatgag ccaggagacg   1260
tacctttacc acatagacaa agtggactcc aacgacagcc tctacggggg agactccaag   1320
ttcctggcag aaaacaacaa gctgtgtgag acggtgatgg ctcagatcct agagcatctg   1380
aaaaccctgg ccaaggacga ggccctgaag cgccagagct cgttgggcct ttccttcttt   1440
aacagcatct tggcccatgg ggacctacgc aacaacaagc tcaaccagct ctccgtcaac   1500
ctgtggcacc tggcacagag gcacggctgt gcagacacca ggaccatggt gaaaacgcta   1560
gaatacatca agaagcaaag caaacaacca gacatgactc atctgacgga gctggcccty   1620
agactccntc tgsaaacaag gacctgaccc ccgggcccat ccccaggcty arggactctg   1680
gtgccaaatc cagaaagatc tgctctgctg ccctgaactc ttacggcaat ttaggttnct   1740
catttttctt ttctttttac atatgtacaa attgttttaa gctttggcct ctatccaggt   1800
tattctgaca atgaagaaat gggagttgtc agagcattaa aatgca                  1846

<210> 1141
<211> 710
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<400> 1141
gntcngtgat tttggacact gctcacactt cattktkatm amcagcccca acttctgcac     60
ctcagcaaag gatgcctttg tcattctggt ggagaatgct ttgcgagtgg ctaccatcaa    120
cacagtagga gattttatgt tattccttgg caaggtgctg atagtctgca gcacaggttt    180
agctgggatt atgctgctca actaccagca ggactacaca gtatgggtgc tgcctctgat    240
catcgtctgc ctctttgctt ycctagtcgc tcattgcttc ctgtctattt atgaaatggt    300
agtggatgta ttattcttgt gttttgccat tgatacaaaa tacaatgatg ggagccctgg    360
cagagaattc tatatggata aagtgctgat ggagtttgtg gaaaacagta ggaaagcaat    420
gaaagaagct ggtaagggag gcgtcgctga ttccagagag ctaaagccga tgctgaagaa    480
aaggtgactg gtctcatgag ccctgaagaa tgaactcaga ggaggttgtt tacatgaggt    540
tctcccactc accagctgtt gagagtctgc gattatgaag agcaggatct tattacttca    600
atgaaagcat gtaacaagtt tctcaaacca ccaacagcca agtggatttg gtacagtgcg    660
gctgtctaat aaataatcaa aagcaaaaaa aaaaaaaaaa aaaactcgag               710

<210> 1142
<211> 606
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (528)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (534)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (556)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (571)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (592)
<223> n equals a,t,g, or c

<400> 1142
ggtcaagggc accctggaag gtgatgtttg tggtgtggag cctcctggcc caggagacac     60
agtagtccag ggagacctgc aggagaccac cgtggtgaca ggcctgggac cagacacaca    120
ggacctggaa ggccagagcc ctccacagag cctgccttca acccccaaag cagcttggat    180
cagggaggag ggccgctgct ccagcagtga cgatgacacc gacgtggaca tggagggtct    240
gcggagacgg cggggcggac cggccacctc agcccatggt gcccctggct gtggagaacc    300
aggctggggg tgagggtgca ggcggggagc tgggcatctc cctcaacatg tgcctccttg    360
gggccctggt tctgcttggc ctgggggtcc tcctcttctc aggtggcctc tcagagtctg    420
agactgggcc catggaggaa gtggagcggc aggtcctccc agaccccgag gtgctggaag    480
ctgtggggga caggcaggat gggctaaggg aacagctgca ggccccantg cctnctgaca    540
agtgtcccag ccttgnaaaa catgggtctt ntgctggaca aagctggcca angagaacca    600
ggacat                                                               606

<210> 1143
<211> 451
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (323)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (420)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (432)
<223> n equals a,t,g, or c

<400> 1143
tcgacccacg cgtccgaagc ccagcagtat ctgatggata atccaacttt tgcagaagat     60
gaggagttac aaaatatgga caaagaagat gcattaattt gctttgaaga acacattcgg    120
gctttagaaa aggaggaaga agaagaaaaa cagaagagtt tgctgagaga aaggagacga    180
cagcgaaaaa atagggaatc tttccagata tttttagatg aattacatga acatggacaa    240
ctgcattcta tgtcatcttg gatggaattg tatccaacta ttagttctga tattagatca    300
ctaatatgct tggtcagcct ggntcaactg cacttgatct tttcaagttt tatgttgagg    360
gatcttaaag cacgttatcc atgacgagaa gaaggttaat aaaagacatt ctaaagggan    420
tttnttaaga anaaaaagaa ggggggggga a                                   451

<210> 1144
<211> 990
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (871)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (909)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (980)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (990)
<223> n equals a,t,g, or c

<400> 1144
gggtccggcg ggcatcggca agaccatggc ggccaaaaat atcctgtacg actgggcggc     60
gggcaagctg taccagggcc aggtggactt cgccttcttc atgccctgcg gcgagctgct    120
ggagaggccg ggcacgcgca gcctggctga cctgatcctg gaccagtgcc ccgaccgcgg    180
cgcgccggtg ccgcagatgc tggcccagcc gcagcggctg ctcttcatcc tggacggcgc    240
ggacgagctg ccggcgctgg ggggccccga ggccgcgccc tgcacagacc ccttcgaggc    300
ggcgagcggc gcgcgggtgc taggcgggct gctgagtaag gcgctgctgc ccacggccct    360
cctgctggtg accacgcgcg ccgccgcccc cgggaggctg cagggccgcc tgtgttcccc    420
gcagtgcgcc gaggtgcgcg gcttctccga caaggacaag aagaagtatt tctacaagtw    480
yttccgggat gagaggaggg ccgagcgcgc ctaccgcttc gtgaaggaga acgagacgct    540
gttcgcgctg tgcttcgtgc ccttcgtgtg ctggatcgtg tgcaccgtgc tgcgccagca    600
gctggagctc ggtcgggacc tgtcgcgcac gtccaagacc accacgtcag tgtacctgct    660
tttcatcacc agcgttctga gctcggctcc ggtagccgac gggccccggt tgcagggcga    720
cctgcgcaat ctgtgccgcc tggcccgcga gggcgtcctc ggacgcaagg cgcaatttgc    780
craaaaggaa ctggagcaac tggagcttcg tggctccaaa agtgcagacg cttgtttctc    840
agcaaaaagg agctgcccgg gcgtgctgga nacagaggtc acctaccagt tcatcgacca    900
agagctttnc aggagttcct cgcgggcact tgtcctacct tgctggaagg acgggcgggg    960
tggcccaagg aaccgccggn ttgggcggcn                                     990

<210> 1145
<211> 1057
<212> DNA
<213> Homo sapiens

<400> 1145
gccaccatcg gctactgcca gggcctgaac aggctggcgg ccattgccct gctggtccta     60
gaggaggagg agagcgcctt ctggtgcctg gtggccattg tggagaccat catgcccgct    120
gattactact gcaacacgct gacggcatcc caggtggacc arcgggtgct ccargacctg    180
ctctcggaga agctgcccag gctgatggcc catctggggc agcaccacgt ggatctctcc    240
ctcgtcacct tcaactggtt cctcgtggtc tttgcggaca gtctcattag caacatcctc    300
cttcgggtct gggatgcctt cctgtacgag gggacgaagg tggtgtttcg ctatgccttg    360
gccattttca agtacaacga gaaggagatc ttgaggctac agaatggcct ggaaatctac    420
cagtacctgc gcttyttcac caagaccatc tccaacagcc ggaagctgat gaacatcgcc    480
ttcaatgaca tgaacccctt ccgcatgaaa cagctgcggc agctgcgcat ggtccaccgg    540
gagcggctgg aggctgagct gcgggagctg gagcagctta aggcagagta cctggagagg    600
cgggcatccc ggcgcagagc tgtgtccgag ggctgtgcca gcgaggacga ggtggagggg    660
gaagcctgac ttggccacct cccctcccca cagccttcct cacccttggc tggcagaccc    720
actggaggtc aggcacggac cagtggccca gccctgggtg tcccatcacc atgtgacctt    780
ggacatgtcc cttcccctct ctggccctca gtttccccac tgggacattg tgtgctgcaa    840
agccattggt tgggctactt cttcataggc acttacttac ccagggatgc caccctttcg    900
tcacctcttc cacagagcac tttggcatgt aaacaagcaa gagcactgcc tctatagggt    960
aacctggaac attctctagg ttatatcaat ataaaacaat gtaaatggtg gaaaaaaaaa   1020
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                            1057

<210> 1146
<211> 733
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (726)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (729)
<223> n equals a,t,g, or c

<400> 1146
gacaacgtcc agccgttcct tcaagcactc ccgctctgct gccgtcacct cagagttcca     60
cttggtgcct agccgcagca tgaatgggca gccactgact tgtgtggtgt cccatcctgg    120
cctgctccag gaccaaagga tcacccacat cctccacgtg tccttccttg ctgaggcctc    180
tgtgaggggc cttgaagacc aaaatctgtg gcacattggc agagaaggag ctatgctcaa    240
gtgcctgagt gaagggcagc cccctccctc atacaactgg acacggctgg atgggcctct    300
gcccagtggg gtacgagtgg atggggacac tttgggcttt cccccactga ccactgagca    360
cagcggcatc tacgtctgcc atgtcagcaa tgagttctcc tcaagggatt ctcaggtcac    420
tgtggatgtt cttgaccccc aggaagactc tgggaagcag gtggacctag tgtcagcctc    480
ggtggtggtg gtgggtgtga tcgccgcact cttgktctgc cttctggtgg tggtggtggt    540
gctcatgtcc cgataccatc ggcgcaaggc ccarcagatg acccagaaat atgargagga    600
gctgaccctg accagggaga actycatccg gaggctgcat tcccatcaca cggaccccag    660
gagccarccg gaggaragtg tagggctkar agccgagggc caccctgata gtctyaaggr    720
ccaatngtnt ttg                                                       733

<210> 1147
<211> 572
<212> DNA
<213> Homo sapiens

<400> 1147
aggaaaaaca aaattaatca cttaaatgaa aatacttttg cacctctcca gaaactggat     60
gaattggatt taggaagtaa taagattgaa aatcttccac cgcttatatt caaggacctg    120
aaggagctgt cacaattgaa tctttcctat aatccaatcc agaaaattca agcaaaccaa    180
tttgattatc ttgtcaaact caagtctctc ctagaaggga ttgaaatttc aaatatccaa    240
taaaggatgt ttagacctct tatgaatctc tctcacatat attttaagaa attccagtac    300
tgtgggtatg caccacatgt tcgcagctgt aaaccaaaca ctgatggaat ttcatctcta    360
gagaatctct tggcaagcat tattcagaga gtatttgtct gggttgtatc tgcagttacc    420
tgctttggaa acatttttgt catttgcatg cgaccttata tcaggtctga gaacaagctg    480
tatgccatgt caatcatttc tctctgctgt gccgactgct taatgggaat atatttattc    540
gtgatcggag gctttgacct aaagtttcgt gg                                  572

<210> 1148
<211> 1166
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1147)
<223> n equals a,t,g, or c

<400> 1148
ctgcatgcat gggacaggat gctttcatgg agcccttcgg tgacacactt ggggtctttc     60
agtgcaaaat atacctcctt ctcttcggtg cttgctcggg gctgaaggtg acagtgccat    120
cacacactgt ccatggcgtc agaggtcagg ccctctacct acccgtccac tatggcttcc    180
acactccagc atcagacatc cagatcatat ggctatttga gagaccccac acaatgccca    240
aatacttact gggctctgtg aataagtctg tggttcctga cttggaatac caacacaagt    300
ttcaccatga tgccacccaa tggcatctct gcttatcaac ccatgcagtt ccctgatgaa    360
ggcaattaca tcgtgaaggt caacattcag ggaaatggaa tctatctgcc mgtcagaaga    420
tacawgtcac ggttgatgat cctgtcacaa agccagtggt gcagattcat cctccctctg    480
gggctgtgga gtatgtgggg aacatgaccc tgacatgcca tgtggaaggg ggcactcggc    540
tagcttacca atggctaaaa aatgggagac ctgtccacac cagctccacc tactcctttt    600
ctccccaaaa caataccctt catattgctc cagtaaccaa ggaagacatt gggaattaca    660
gctgcctggt gaggaaccct gtcagtgaaa tggaaagtga tatcattatg cccatcatat    720
attatggacc ttatggactt caagtgaatt ctgataaagg gytaaaakta ggggaagtgt    780
ttactgttga ccttggagag gccatcctat ttgattgttc tgctgattct catcccccca    840
acacctactc ctggattagg aggactgaca atactacata tatcattaag catgggcctc    900
gcttagaagt tgcatctgag aaagtagccc agaagacaat ggactatgtg tgctgtgctt    960
acaacaacat aaccggcagg caagatgaaa ctcatttcac agttatcatc acttccgtag   1020
gactggagaa gcttgcacag aaaggaaaat cattgtcacc tttagcaagt ataactggaa   1080
tatcactatt tttgattata tccatgtgtc ttctcttcct atggaaaaaa tatcaaccct   1140
acaaagntat aaaaaaaaaa aaaaag                                        1166

<210> 1149
<211> 739
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (678)
<223> n equals a,t,g, or c

<400> 1149
ggcacaggca aatacctgta tccccagtat ttccagtatt ggtaattttt cctgatgcgt     60
gcagatcctc caaagtttaa taggatatgg ccgaatattt cttcccttga ggtttctaac    120
ccaaaacaag ttgctcccaa attagctttg tcaacagttt cttctgttca agttgcaaac    180
cacaagagag cgaatgtctg cgacaacgag ctcctgcact gccagaacgg agggacgtgc    240
cacaacaacg tgcgctgcct gtgcccggcc gcatacacgg gcatcctctg cgagaagctg    300
cggtgcgagg aggctggcag ctgcggctcc gactctggcc agggcgcgcc cccgcacggc    360
tccccagcgc tgctgctgct gaccacgctg ctgggaaccg ccagccccct ggtgttctag    420
gtgtcacctc cagccacacc ggacgggcct gtgccgtggg gaagcagaca caacccaaac    480
atttgctact aacataggaa acacacacat acagacaccc ccactcagac agtgtacaaa    540
ctaagaaggc ctaactgaac taagccatat ttatcacccg tggacagcac atccgagtca    600
agactgttaa tttctgactc cagaggagtt cggcagctgt tgatattatc actgcaaatc    660
acattgccag ctgcaganat attgtggatt ggaaaggctg cgacagcccc caaacaggga    720
agacacaaaa cacacacat                                                 739

<210> 1150
<211> 909
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<400> 1150
gnaaattant tttcaagagg aaatttaaat aacgactcat agtaaaccaa atacaaaaca     60
aaagcttttt tttttttagt ttgtttcaca gtatctaaaa tggcagagat ttcaggaaag    120
tctaatcaca cttgaccatg agtgttgagt tgcttttcct tcctctgagg ccaagagtta    180
cttatatcca agaccgtgaa gaactctttt tgacctgttg gatatgatct tgtgactggg    240
tcgaggaaaa tgaactccca gggttgttgg agtagagctg tttccaccaa aagacagaac    300
tgtatgcagc taataagagc tccagcacag tgaagatgag catcaccact aggacacctg    360
ttaaactgac actggtcagg agacaatctt tgatttcata tattggataa tagtactccg    420
aataaggcaa tgaggataga taatccattt ctgagccaca atgttgagag gcagtcctca    480
gggctaccat gctgtcagca aggaggaaga ggcctgctcc tgcagtaaca gaactcactg    540
catttgaggt caarctgctc aggtcaaagg gcttagttga ttgttttcca gagataattg    600
agagggatcc agtaatgcca aacccaagaa cggtggtttc tgttggcagc ccgttctgca    660
ggtaatcytc gttttggtac atgtgtccag gtttctctct ttgagggata gtgatgccct    720
ttggtgtaaa gctgtgagaa acccccatgg tttgggattg taatagcatg atgctgatga    780
tgctgttctc gcagcctggt cctgtgtgct gtggctgggg atcagctcac ctctggggag    840
cgctcagctg gaacctccca ctggctgttc ctgccagaac ratcttggtg ctctgcccca    900
cgcgtccgc                                                            909

<210> 1151
<211> 915
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (172)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (724)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (825)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (845)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (848)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (855)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (886)
<223> n equals a,t,g, or c

<400> 1151
ggagcgcaac gcaattaatg tgagttagct cactcattag gcaccccagg ctttacactt     60
tatgcttccg gctcgtatgt tgtgtggaat tgtgagcgga taacaatttc ncacaggaaa    120
cagctatgac catgattacg ccaagctcga aattaaccct cactaaaggg ancaaaagct    180
ggagctccac cgcggtggcg gccgctctag aactagtgga tcccccgkkc tgcaggaatt    240
cggcacgaga ggacataaca gaagcaatag agactaccat tagtcttgaa acagcacgtg    300
cagaccatcc gaagcctgta actgtgaaac cagtaacaac ggaacctcag agtccagatc    360
tgaacgatgc cgtgtccagt ttgcgaagtc ctattcccct cctcctgtcg tgtgcctttg    420
ttcaggtggg gatgtatttc atgtagaagg tggaagaagg ctgctatgac tctttggatg    480
ggagtctggc aagaggaaat tggaagataa aataaataat aagtgaaata aaaaaaaaaa    540
aaaaaaaaaa aaaaaaaact cgaggggggg cccggtaccc aattcgccct atagtgagtc    600
gtattacaat tcactggccg tcgttttaca acgtcgtgac tgggaaaacc ctggcgttac    660
ccaacttaat cgccttgcag cacatccccc tttcgccagc tggcgtaata gcgaagaggc    720
ccgnaccgat cgccttccaa cagttgcgca acctgaatgg cgaatggcaa attgtaaagc    780
gttaatattt tggtaaaatt cgcggtaaat tttggtaaat caagntcatt ttttaaccaa    840
taggnccnaa tcggnaaaat cccttataaa tcaaaaggaa tttganccgg gaatagggtt    900
gaatggttgt tccaa                                                     915

<210> 1152
<211> 1380
<212> DNA
<213> Homo sapiens

<400> 1152
gggcaggtgt ccgaccatga gcgtccgggt cgcacgggta gcgtgggtca ggggcttggg     60
cgccagctac cgccgcggcg cctcgagctt cccggtgcct ccgccgggcg cccagggtgt    120
agcggagctg ctgcgagatg cgaccggggc ggaggaggag gcgccctggk cggcgacgga    180
gcggcgaatg ccgggccagt gctccgtgct gctcttcccg ggccagggca gccaggtggt    240
gggcatgggc cgcggtctgc tcaactaccc gcgcgtccgc gaactctacg ccgccgcccg    300
ccgcgtgctg ggctacgacc tgctggaact gagcctgcac gggccgcagg agaccctgga    360
ccgcaccgtg cactgtcagc ccgcgatctt cgtggcatcg ctggccgctg tcgagaaact    420
acatcacctg cagccctcgg tgattgagaa ctgtgttgct gctgctggat tcagtgtggg    480
agagtttgca gccctagtgt ttgccggagc catggaattt gctgaaggtt tgtatgcagt    540
gaaaatccga gctgaggcca tgcaggaagc ttcagaagct gtccccagtg ggatgctgtc    600
tgtcctcggc cagcctcagt ccaagttcaa cttcgcctgt ttggaagccc gggaacactg    660
caagtyttta ggcatagaga accccgtatg tgaagtgtcc aactacctct ttccagattg    720
cagggtgatt tcaggacacc aagaggctct acggtttctc cagaagaatt cctctaagtt    780
tcatttcaga cgcaccagga tgttgccggt tagtggcgca ttccacaccc gcctcatgga    840
gccagccgtg gagcccctga cgcaagcttt aaaggcagtc gacattaaga agcctctggt    900
ttctgtctac tccaacgtcc acgsgcatag atacaggcat cccgggcaca tccacaagct    960
gctggcccag cagctggtct ccccagtgaa gtgggagcag acgatgcatg ccatatacga   1020
aaggaaaaag ggcagggggt tcccccaaac tttcgaagta ggccctggca ggcagctggg   1080
agccatcctg aagagctgta acatgcaggc ctggaagtcc tacagcgccg tggatgtgct   1140
gcagaccctc gaacatgtgg acctggaccc tcaggagccc ccgagatgac tgcagggggc   1200
tcaaatgcra tgaccccctc tgtcctcctg aggagaggct gtaggctgtg cctgtcgccc   1260
cctaccttcc taatggctcc tcctctgagg agtgaaaggg atttgtttgc aacgtgcttt   1320
gaaggccaca taaaaagccc taaaaatgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1380

<210> 1153
<211> 1947
<212> DNA
<213> Homo sapiens

<400> 1153
cgctgcgact cagacctcag ctccaacata tgcattctga agaaagatgg ctgagatgga     60
cagaatgctt tattttggaa agaaacaatg ttctaggtca aactgagtct accaaatgca    120
gactttcaca atggttctag aagaaatctg gacaagtctt ttcatgtggt ttttctacgc    180
attgattcca tgtttgctca cagatgaagt ggccattctg cccgcccctc agaacctctc    240
tgtactctca accaacatga agcatctctt gatgtggagc ccagtgatcg cgcctggaga    300
aacagtgtac tattcygtcg aataccaggg ggagtacgag agcctgtaca cgagccacat    360
ctggatcccc agcagctggt gctcactcac tgaaggtcct gagtgtgatg tcactgatga    420
catcacggcc actgtgccat acaaccttcg tgtcagggcc acattgggct cacagacctc    480
agcctggagc atcctgaagc atccctttaa tagaaactca accatcctta cccgacctgg    540
gatggagatc accaaagatg gcttccacct ggttattgag ctggaggacc tggggcccca    600
gtttgagttc cttgtggcct actggaggag ggagcctggt gccgaggaac atgtcaaaat    660
ggtgaggagt gggggtattc cagtgcacct agaaaccatg gagccagggg ctgcatactg    720
tgtgaaggcc cagacattcg tgaaggccat tgggaggtac agcgccttca gccagacaga    780
atgtgtggag gtgcaaggag aggccattcc cctggtactg gccctgtttg cctttgttgg    840
cttcatgctg atccttgtgg tcgtgccact gttcgtctgg aaaatgggcc ggctgctcca    900
gtactcctgt tgccccgtgg tggtcctccc agacaccttg aaaataacca attcacccca    960
gaagttaatc agctgcagaa gggaggaggt ggatgcctgt gccacggctg tgatgtctcc   1020
tgaggaactc ctcagggcct ggatctcata ggtttgcgga agggcccagg tgaagccgag   1080
aacctggtct gcatgacatg gaaaccatga ggggacaagt tgtgtttctg ttttccgcca   1140
cggacaaggg atgagagaag taggaagagc ctgttgtcta caagtctaga agcaaccatc   1200
agaggcaggg tggtttgtct aacagaacac tgactgaggc ttaggggatg tgacctctag   1260
amtgggggct gccacttgct ggctgagcaa ccctgggaaa agtgacttca tcccttcggt   1320
cctaagtttt ctcatctgta atgggggaat tacctacaca cctgctaaac acacacacac   1380
agagtctctc tctatatata cacacgtaca cataaataca cccagcactt gcaaggctag   1440
agggaaactg gtgacactct acagtctgac tgattcagtg tttctggaga gcaggacata   1500
aatgtatgat gagaatgatc aaggactcta cacactgggt ggcttggaga gcccactttc   1560
ccagaataat ccttgagaga aaaggaatca tgggagcaat ggtgttgagt tcacttcaag   1620
cccaatgccg gtgcagaggg gaatggctta gcgagctcta cagtaggtga cctggaggaa   1680
ggtcacagcc acactgaaaa tgggatgtgc atgaacacgg aggatccatg aactactgta   1740
aagtgttgac agtgtgtgca cactgcagac agcaggtgaa atgtatgtgt gcaatgcgac   1800
gagaatgcag aagtcagtaa catgtgcatg tttgttgtgc tccttttttc tgttggtaaa   1860
gtacagaatt yagcaaataa aaagggccac cctggccaaa agcggtcaaa aaaaaaaaaa   1920
aaaaaaaaaa aaaaaaaaag ggcggcc                                       1947

<210> 1154
<211> 2787
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2787)
<223> n equals a,t,g, or c

<400> 1154
aacattgact gcstcmggtc tcaagcacca gtcttcaccg cggaaagcat gttgtggctg     60
ttccaatcgc tcctgtttgt cttctgcttt ggcccaggga atgtagtttc acaaagcagc    120
ttaaccccat tgatggtgaa cgggattctg ggggagtcag taactcttcc cctggagttt    180
cctgcaggag agaaggtcaa cttcatcact tggcttttca atgaaacatc tcttgccttc    240
atagtacccc atgaaaccaa aagtccagaa atccacgtga ctaatccgaa acagggaaag    300
cgactgaact tcacccagtc ctactccctg caactcagca acctgaagat ggaagacaca    360
ggctcttaca gagcccagat atccacaaag acctctgcaa agctgtccag ttacactttg    420
aggatattaa gacaactgag gaacatacaa gttaccaatc acagtcagct atttcagaat    480
atgacctgtg agctccatct gacttgctct gtggaggatg cagatgacaa tgtctcattc    540
agatgggagg ccttgggaaa cacactttca agtcagccaa acctcactgt ctcctgggac    600
cccaggattt ccagtgaaca ggactacacc tgcatagcag agaatgctgt cagtaattta    660
tccttctctg tctctgccca gaagctttgc gaagatgtta aaattcaata tacagatacc    720
aaaatgattc tgtttatggt ttctgggata tgcatagtct tcggtttcat catactgctg    780
ttacttgttt tgaggaarag aagagattcc ctatctttgt ctactcagcg aacacagggc    840
cccgagtccg caaggaacct agagtatgtt tcagtgtctc caacgaacaa cactgtgtat    900
gcttcagtca ctcattcaaa cagggaaaca gaaatctgga cacctagaga aaatgatact    960
atcacaattt actccacaat taatcattcc aaagagagta aacccacttt ttccagggca   1020
actgcccttg acaatgtcgt gtaagttgct gaaaggcctc agaggaattc gggaatgaca   1080
cgtcttctga tcccatgaga cagaacaaag aacaggaagc ttggttcctg ttgttcctgg   1140
caacagaatt tgaatatcta ggataggatg atcacctcca gtccttcgga cttaaacctg   1200
cctacctgag tcaaacacct aaggataaca tcatttccag catgtggttc aaataatatt   1260
ttccaatcca cttcaggcca aaacatgcta aagataacac accagcacat tgactctctc   1320
tttgataact aagcaaatgg aattatggtt gacagagagt ttatgatcca gaagacaacc   1380
acttctctcc ttttagaaag cagcaggatt gacttattga gaaataatgc agtgtgttgg   1440
ttacatgtgt agtctctgga gttggatggg cccatcctga tacaagttga gcatcccttg   1500
tctgaaatgc ttgggattag aaatgtttca gatttcaatt ttttttcaga ttttggaata   1560
tttgcattat atttagcggt tgagtatcca aatccaaaaa tccaaaattc aaaatgctcc   1620
aataagcatt tcccttgagt ttcattgatg tcgatgcagt gctcaaaatc tcagattttg   1680
gagcattttg gatattggat ttttggattt gggatgctca acttgtacaa tgtttattag   1740
acacatctcc tgggacatac tgcctaacct tttggagcct tagtctccca gactgaaaaa   1800
ggaagaggat ggtattacat cagctccatt gtttgagcca agaatctaag tcatccctga   1860
ctccagtgtc tttgtcacca ggccctttgg actctacctc agaaatattt cttggacctt   1920
ccacttctcc tccaactcct tgaccaccat cctgtatcca accatcacca cctctaacct   1980
gaatcctacc ttaagatcag aacagttgtc ctcacttttg ttcttgtccc tctccaaccc   2040
actctccaca agatggccag agtaatgttt ttaatataaa ttggatcctt cagtttcctg   2100
cttaaaaccc tgcaggtttc ccaatgcact cagaaagaaa tccagtttcc atggccctgg   2160
atggtctggc ccacctccag cctcagctag cattaccctt ctgacactct ctatgtagcc   2220
tccctgatct tctttcagct cctctattaa aggaaaagtt ctttatgtta attatttaca   2280
tcttcctgca ggcccttcct ctgcctgctg gggtcctcct attctttagg tttaatttta   2340
aatatgtcac ctcctaagag aaaccttccc agaccactct ttctaaaatg aatcttctag   2400
gctgggcatg gtggctcaca cctgtaatcc cagtactttg ggaggccaag gggggagatc   2460
acttgaggtc aggagttcaa gaccagcctg gccaacttgg tgaaaccccg tctttactaa   2520
aaatacaaaa aaattagcca ggcgtggtgg tgcaccccta aaatcccagc tacttgagag   2580
actgaggcag gagaatcact tgaacccagg aggtggaggt tccagtgagc caaaatcatg   2640
ccaatgtatt tccagtctgg gtgacagagt gagactctgt ctcaaaaaat aaataaataa   2700
aataaaatga aatagatctt aaaaaaaaaa aaaaaaaggg cggccgctct agaggakcca   2760
mgctkacgta cgcgtgcatg cgacgtn                                       2787

<210> 1155
<211> 1233
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (72)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (93)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (135)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (163)
<223> n equals a,t,g, or c

<400> 1155
atggaaaaac gccagcaacg cggccttttt acggttcctg gccttttgnt ggccttttgc     60
tcacatgttc tntcctgcgt tatcccctga ttntgtggat aaccgtatta ccgcctttga    120
gtgagctgat accgntcgcc gcagccgaac gaccgagcgc agngagtcag tgagcgagga    180
agcggaagag cgcccaatac gcaaaccgcc tctcccccgc gcgttggccg atttcattaa    240
tgcagctggc acgacaggtt tcccgactgg aaagcgggca gtgagcgcaa cgcaattaat    300
gtgagttagc tcactcatta ggcaccccag gctttacact ttatgcttcc ggctcgtatg    360
ttgtgtggaa ttgtgagcgg ataacaattt cacacaggaa acagctatga ccatgattac    420
gccaagctcg aaattaaccc tcactaaagg gaacaaaagc tggagctcca ccgcggtggc    480
ggccgctcta gaactagtgg atcccccggg ctgcaggaat tcggcacgag catggttgtt    540
gcaaaacttt cttctatttc ttctcctcct ggtattctca ttactctgtt tcaccttgtg    600
tagttgtccc acagtcttgg atatcatctt ctgttctttt cagtgtttct tttctttagt    660
tttcgaagtt tctgatgata aatcctcaag ctcagagatt ctttactcag ctgagtccag    720
tctactaata agccatcaga ggtattcttc agttatttaa cacatttttt accactacat    780
tatgttgaag tttcttacga tgtctgtctt tctgattaca ttacccatct acacttgaat    840
gctgtctact tcattcatta gacccttagc atattctcca gaggtttaaa aaaatttcca    900
aaatcataac tttgtctgct tctgaagctt gctctgttga cacaaattgt atttttttct    960
ttttttggat tttagtatgc cttgcaattt tttcccttta ttctcatgca tgaagcaccc   1020
cactaaargt gactgytgtt agtatagctt tartaatgcg gtgatgargt gacagggcag   1080
gtgatgctct cttagtctct ttargctact ataacaaaat actttagact gagccsaata   1140
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaac tcgagggggg   1200
gcccgaccca attcgcccta ctacgtgcgt cga                                1233

<210> 1156
<211> 754
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (729)
<223> n equals a,t,g, or c

<400> 1156
gtcgacccac gcgtccgccc acgcgtccgc ccacgcgtcc ggtttataaa cagaagttta     60
aacttgtaag cttaagcttc cgtttataaa cagaagttta aaattatagg tcctgtttaa    120
cattcagctc tgttaactca ctcatctttt tgtgttttta cactttgtca agatttcttt    180
acatattcat caatgtctga agaagttact tatgcagatc ttcaattcca gaactccagt    240
gagatggaaa aaatcccaga aattggcaaa tttggggaaa aagcacctcc agctccctct    300
catgtatggc gtccagcagc cttgtttctg actcttctgt gccttctgtt gctcattggr    360
ttgggagtct tggcaagcat gtttcatgta actttgaaga tagaaatgaa aaaaatgaac    420
aaactacaaa acatcagtga agagctccag agaaatattt ctctacaact gatgagtaac    480
atgaatatct ccaacaagat caggaacctc tccaccacac tgcaaacaat agccaccaaa    540
ttawgtcgtg agytatatag saaagaacma gagcacaaat gtaagccttg tccaaggaga    600
tggatttggc ataaggacag ctgttatttc ctaagtgatg atgtccaaac atggcaggag    660
agtaaaatgg cctgtgctgc tcagaatgcc agcctgttga agataaacaa caaaaatgca    720
ttggaattng taaaatccca gagtggcaat agga                                754

<210> 1157
<211> 1842
<212> DNA
<213> Homo sapiens

<400> 1157
aattcggcag agtttcaggg tcttgttccc aatcagtttc cagccaacac cagggtgtcc     60
tagtccgcag aggtgtgggg gacacactcc ataatctcta cttttctttt tgtgcagctg    120
agtcatggag ctttcagccc cagcacatgg ctcctcctta actgcgtctg ctcaacctcc    180
ctcagccctg tgaacagcat ccccgcacac agacgcagag caggactctc tctgctgcca    240
cttcaccttc ctgagagagg accagcggcc agagcctcag tgactgccac cctggaggac    300
agggcacaac aaccgtttct ggagagaatg ggaggattcc agaggggcaa atatggaact    360
atggctgaag gtagatcaga agataacttg tctgcaacac caccggcatt gaggattatc    420
ctagtgggca aaacaggctg cgggaaaagt gccacaggga acagcatcct tggccagccc    480
gtgtttgagt ccaagctgag ggcccagtca gtgaccagga cgtgccaggt gaaaacagga    540
acatggaacg ggaggaaagt cctggtggtt gacacgccct ccatctttga gtcacaggcy    600
gatacccaag agctgtacaa gaacatcggg gactgctacc tgctctctgc cccggggccc    660
cacgtcctgc ttctggtgat ccagctgggg cgtttcactg ctcaggacac agtggccatc    720
aggaaggtga aagaggtctt tgggacaggg gccatgagac atgtggtcat cctcttcacc    780
cacaaagagg acttaggggg ccaggccctg gatgactatg tagcaaacac ggacaactgc    840
agcctgaaag acctggtgcg ggagtgtgag agaaggtact gtgccttcaa caactggggc    900
tctgtggagg agcagaggca gcagcaggca gagctcctgg ctgtgattga gaggctgggg    960
agggagcgag agggctcctt ccacagcaat gacctcttct tggatgccca gctgctccaa   1020
agaactggag ctggggcctg ccaggaagac tacaggcagt accaggccaa agtggaatgg   1080
caggtggaga agcacaagca agagctgagg gagaacgaga gtaactgggc atacaaggcg   1140
ctyctcagag tcaaacactt gatgcttttg cattatgaga tttttgtttt tctattgttg   1200
tgcagcatac tttttttcat tatttttctg ttcatctttc attacattta aatctctgga   1260
ccctggagca cttctaatgt atcaccccat ggagtcattg ttctaataat caccaattca   1320
gactcagatc ctcgtggtct atggagcatg ctgcttgctg tctgtgcagc tcccatttcc   1380
ccttcttcct gatagacttg gagctgtgtg cctccactcc aaggctgcct gcctgctgta   1440
aacactattc cactctgtct gccaacaact gcttcaggaa tgggcctgag atcccatgca   1500
ggtccctgag aagtgagtaa aagtccgcag aggtggggat ggaagatctc tccttagata   1560
gaacctgtct tcctccctgg cattgtgggg tctgggcgtg acactgggac tctcagcagc   1620
tttgtgctgc caacctgaga ttgaaggcag tgcctcagag cagcacagag agttggggcc   1680
ccctgagccc tgagccacca gccctgcagc ctgccctatc tccgcatttc cagttgtatt   1740
agccaatara tttcctactt atttaagcta tttgagctcc gggtctcttc tacctgcatt   1800
ctaaaacatt caaagtaata aaaatttctc cacattaaaa aa                      1842

<210> 1158
<211> 460
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (226)
<223> n equals a,t,g, or c

<400> 1158
ggtcaagtgg cttcttctga gcgctgaggg aggggagcgt gcgtagggga tggtgccagc     60
gctgcgttat ttggttggtg cctgcggacg ggcccgcggg cttttcgccg gtggctcccc    120
tggggcgtgc gggttcgcgt ctgggaggcc aagaccgctg tgtggaggta gccgcagcgc    180
cagcaccagc tcatttgata tagtcatcgt tggtggcgga attgtngggc ttgcctctgc    240
cagagcactc atcctgcgac atccatcact ttctattggt gttctggaaa aggagaaaga    300
tttagctgtt caccagactg gacataacag tggtgtyata catagtggaa tttattataa    360
accygagtct ctgaaaagcc aaattatgtg tacaaggtgc agccctcctc tatgagtact    420
gtcagcaaaa gggaatttcc tacaagcagt gtggcaagct                          460

<210> 1159
<211> 1924
<212> DNA
<213> Homo sapiens

<400> 1159
ccgtgacatt aaaaaaacgt acgcctgcag gtcccggtcc ggaaattccc gggtcgaccc     60
acgcgtccgg cgatgagtgc ctctgcggcc accggggtct tcgtgctgtc cctctcggcc    120
aycccggtca cctatgtctt caaccacctg gcggcccagc atgattcctg gactattgta    180
ggggttgctg ccctcatcct gttcctggta gcactgctgg ctcgtgtcct cgtcaaaaga    240
aaaccacccc gggacccact gttctatgtg tatgcagttt ttggatttac cagcgtggtg    300
aacctcatca taggactgga gcaagatgga atcattgacg ggttcatgac acactacttg    360
agagagggtg aaccgtatct gaacaccgca tatgggcaca tgatctgcta ctgggatggc    420
tctgcttcat tatctgatgt acctggtgat ggtggcagcc atagcatggg aggaaactta    480
tagaaccatt ggcctatatt gggttggatc tattattatg agtgttgttg tttttgtgcc    540
aggaaacatt gtagggaagt atggaacacg aatttgccct gcttttttct taagcatacc    600
atatacttgt cttcctgtct gggctggttt cagaatctat aatcagccat cagaaaatta    660
taattacccc tcaaaggtta ttcaagaagc ccaagcgaaa gacctgctga gaagaccatt    720
tgatttaatg ttggttgtgt gtctcctcct ggcaactgga ttttgcctgt tcagaggttt    780
gattgctttg gattgcccat ctgagctctg ccgattatat acgcaatttc aagagcccta    840
tctaaaggat cctgctgctt atcctaaaat tcagatgctg gcatatatgt tctattctgt    900
tccttacttt gtgactgcac tgtatggctt agtggttcct ggatgttcct ggatgcctga    960
catcacattg atacatgctg gaggtctggc tcaggctcag ttttctcaca ttggtgcatc   1020
tcttcatgct agaactgctt atgtctacag agtccctgaa gaagcaaaaa tccttttttt   1080
agcattaaac atagcatatg gagttcttcc tcagctcttg gcctatcgtt gtatctacaa   1140
accagagttc ttcataaaaa caaaggcaga agaaaaagtg gaataaaaat attacttcat   1200
gttcctcctt tctaaattac taacttttgt tatactggta ctgatatttt gtcccatttc   1260
actctcttct catacgtgag tacttaagaa tatgtacatt cttgctctgc actgtatgtg   1320
tgagctatat ggtattgtgt aaattttttt tgaaggaaaa tggaaattct tgagaaacag   1380
tttgtttaaa gaaatatatt caaaatcatt tgtgaataaa cttgatcatc catctcaata   1440
ttgtttgaca tataaaataa ttataagtgt aaaaaattac aatttagtgc caacagtagt   1500
gagcatgaaa tgaaactatt caaaagagaa tatggcctgt gcatattaaa aaattcaaaa   1560
cagtgaatgc agactggagg agtaactttt gcaaataaga tgaatatgct tcattattaa   1620
actcaatata aaaggcaaat catcagaata tttttaaatg ttgtttgaaa aatgttttcc   1680
caaggaaagt ttattatttg ctgctgtttc aagaaaatta cttttactaa atttttttgt   1740
gtgaatttaa acagctaaat agggatcagt aactttatct ctatccttaa tgaacatttg   1800
ttttattggt ggctggaaat atttctattg tatttctgtg tatattttta ataaaattat   1860
ttttggcctc ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaact   1920
cgag                                                                1924

<210> 1160
<211> 736
<212> DNA
<213> Homo sapiens

<400> 1160
tccgggaatt cccgggtcga cccacgcgtc cgctcaggat gactgtggag aaggaggccc     60
ctgatgcgca cttcactgtg gacaaacaga acatctccct ctggccccga gagcctcctc    120
ccaagtccgg tccatctctg gtcccgggga aaacacccac agtccgtgct gcattaatct    180
gcctgacgct ggtcctggtc gcctccgtcc tgctgcaggc cgtcctttat ccccggttta    240
tgggcaccat atcagatgta aagaccaatg tccagttgct gaaaggtcgt gtggacaaca    300
tcagcaccct ggattctgaa attaaaaara atagtgacgg catggaggca gctggcgttc    360
agatccagat ggtgaatgwg agcctgggtt atgtgcgttc tcagttcctg aagttaaaaa    420
ccagtgtgga gaaggccaac gcasagatcc agatcttaac aagaagttgg gaagaagtca    480
gtaccttaaa tgcccaaatc ccagagttaa aaagtgattt ggagaaagcc agtgctttaa    540
atacaaagat ccgggcactc cagggcagct tggagaatat gagcaagttg ctcaaacgac    600
aaaatgatat tctacaggtg gtttctcaag gctggaagta cttcaagggg aacttctatt    660
acttttctct cattccaaag acctggtata gtgccgagca gttctgtgtg tccaggaatt    720
cacacctgac ctctgg                                                    736

<210> 1161
<211> 1375
<212> DNA
<213> Homo sapiens

<400> 1161
aaacaggaaa taaatacgaa tgaaactgag ctctaagcag catgtaacct ggcctgcatc     60
caggaaatag aggacttcgg atccttctaa ccctaccacc caactggccc cagtacattc    120
attytctcag gaaaaaaaac aaggtcccca cagcaaagaa aaggaatagg atcaagagat    180
acgtggctgc tggcagagca agcatgaatt cgatgacttc agcagttccg gtggccaatt    240
ctgtgttggt ggtggcaccc cacaatggtt atcctgtgac cccaggaatt atgtctcacg    300
tgcccctgta tccaaacagc cagccgcaag tccacctagt tcctgggaac ccacctagtt    360
tggtgtcgaa tgtgaatggg cagcctgtgc agaaagctct gaaagaaggc aaaaccttgg    420
gggccatcca gatcatcatt ggcctggctc acatcggcct cggctccatc atggcgacgg    480
ttctcgtagg ggaatacctg tctatttcat tctacggagg ctttcccttc tggggaggct    540
tgtggtttat catttcagga tctctctccg tggcagcaga aaatcagcca tattcttatt    600
gcctgctgtc tggcagtttg ggcttgaaca tcgtcagtgc aatctgctct gcagttggag    660
tcatactctt catcacagat ctaagtattc cccacccata tgcctacccc gactattatc    720
cttacgcctg gggtgtgaac cctggaatgg cgatttctgg cgtgctgctg gtcttctgcc    780
tcctggagtt tggcatcgca tgcgcatctt cccactttgg ctgccagttg gtctgctgtc    840
aatcaagcaa tgtgagtgtc atctatccaa acatctatgc agcaaaccca gtgatcaccc    900
cagaaccggt gacctcacca ccaagttatt ccagtgagat ccaagcaaat aagtaaggct    960
acagattctg gaagcatctt tcactgggac caaaagaagt cctcctccct ttctgggctt   1020
ccataaccca ggtcgttcct gttctgacag ctgaggaaac gtctctccca ctgtttgtac   1080
tctcaccttc attcttcaat tcagtctagg aaaccatgct gtttctctat caagaagaag   1140
acagagattt taaacagatg ttaaccaaga gggactccct agggcacatg catcagcaca   1200
tatgtgggca tccagcctct ggggccttgg cacacacaca ttcgtgtgct ctgctgcatg   1260
tgagcttgtg ggttagagga acaaatatct agacattcaa tcttcactct ttcaattgtg   1320
cattcattta ataaatagat actgagcatt caaaaaaaaa aaaaaaaaaa ctcga        1375

<210> 1162
<211> 1207
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (113)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (130)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (152)
<223> n equals a,t,g, or c

<400> 1162
tcattaggca ccccaggctt tacactttat gcttccggtt cgtatgttgt gtggaattgt     60
gagcggataa caatttcaca caggaaacag ctatgaccat gattacgcca agntcgaaat    120
taaccctcan taaagggaac aaaagctgga gntccaccgc ggtggcggcc gctctagaac    180
tagtggatcc cccgggctgc aggaattcgg cacgmgtggg ctgcagtagg tcccggcaac    240
cgcaggctcg cggcgggcgc tgggcgcggg atccgactct agtcgtaatg gaggcgggcg    300
gctttctgga ctcgctcatt tacggagcat gcgtggtctt cacccttggc atgttctccg    360
ccggcctctc ggacctcagg cacatgcgaa tgacccggag tgtggacaac gtccagttcc    420
tgccctttct caccacggaa gtcaacaacc tgggctggct gagttatggg gctttgaagg    480
gagacgggat cctcatcgtc gtcaacacag tgggtgctgc gcttcagacc ctgtatatct    540
tggcatatct gcattactgc cctcggaagc gtgttgtgct cctacagact gcaaccctgc    600
taggggtcct tctcctgggt tatggctact tttggctcct ggtacccaac cctgaggccc    660
ggcttcagca gttgggcctc ttctgcagtg tcttcaccat cagcatgtac ctctcaccac    720
tggctgactt ggctaaggtg attcaaacta aatcaaccca atgtctctcc tacccactca    780
ccattgctac ccttctcacc tctgcctcct ggtgcctcta tgggtttcga ctcagagatc    840
cctatatcat ggtgtccaac tttccaggaa tcgtcaccag ctttatccgc ttctggcttt    900
tctggaagta cccccaggag caagacagga actactggct cctgcaaacc tgaggctgct    960
catctgacca ctgggcacct tagtgcmaac ctgaaccaaa gagacctcct tgtttcagct   1020
gggcctgctg tccagcttcc caggtgcagt gggttgtggg aacaagagat gactttgagg   1080
ataaaaggac caaagaaaaa gctttactta gatgattgat tggggcctag gagatgaaat   1140
cactttttat tttttagaga tttttttttt taattttgga ggttggggtg caaytttaga   1200
atatgcc                                                             1207

<210> 1163
<211> 1727
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (353)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (758)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1726)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1727)
<223> n equals a,t,g, or c

<400> 1163
acggagtcag gatacncncc tctggtgggc agagaggata gtaagcccca cagtctgaga     60
ggtgactcca taaaacaaga agaggcccag aaaagctttg ttgacagctg gagacagaga    120
tcaaacactc aaggttccat tttgataaac ctgctcctga agcagccttt gatcccaggg    180
tcatccctaa gcctttgcca cctcctgagt agtagttctg agtctcctgc tggcaccccc    240
ctgcagccac cagggtttgg cagtaccttg gctggaatgt caggcctcag gaccacaggt    300
tcttatgatg ggtcattttc cctctcagcc ctgagagaag cacagaacct ggncattcac    360
tggactgaat ctggttgccc ggaatgagtg ctcacgtgat ggagacccag cagagggagg    420
cagaagggcc ttcccactct gccagcttcc tggagccgtg catttcctcc cccttgtaca    480
gttcttcatc ggcttacact gccaggccct gcaggacttg gcagctgcta agagaagcgg    540
agcacctggg gactcaccga cacattcctc ctgcgtgagc tctggggtag agaccaaccc    600
tgaggactca gtgtgcatcc tggaaggctt ctctgtgact gcacttagca ttcttcagca    660
cctggtgtgc cacagcggag cagtcgtctc cctattactg tcaggagtgg gggcagattc    720
tgctgctggg gaaggaaaca ggagcctggt tcacaggntt agtgatggag atatgacctc    780
agccctaagg ggggttgctg atgaccaagg acagcaccca ctgttgaaga tgcttcttca    840
cctgttggct ttctcttctg cagcaacagg tcaccttcaa gccagtgtcc tgacccagtg    900
ccttaaggtt ttggtgaaat tagccgaaaa cacttcctgt gatttcttgc ccaggttcca    960
gtgtgtgttc caagtgctgc caaagtgcct cagcccagag acacccctgc ctagcgtgct   1020
gctggctgtt gagctcctct ccctgctggc ggaccacgac cagctggcac ctcagctctg   1080
ttcccactca gaaggctgcc tcctgctgct gctgtacatg tacatcacat cacggcctga   1140
cagagtggcc ttggagacac aatggctcca gctggaacaa gaggtggtgt ggctcctggc   1200
taagcttggt gtgcaragcc ccttgccccc agtcactggc tccaactgcc agtgtaatgt   1260
ggaggtggtc agagcgctca cggtgatgtt gcacagacag tggctgacag tgcggagggc   1320
agggggaccc ccaaggaccg accagcagag gcggacagtg cgctgtctgc gggacacggt   1380
gctgctgctg cacggcctat cgcagaagga caagctcttc atgatgcact gcgtggaggt   1440
cctgcatcag tttgaccagg tgatgccggg ggtcagcatg ctcatccgag ggcttcctga   1500
tgtgacggac tgtgaagagg cagccctgga tgacctctgt gccgcggaaa ccgatgtgga   1560
agaccccgag gtggagtgtg gctgaggccc tgagtgtcca gccacatggt ggcaccagca   1620
ccactccttt ccttaccaca tcaactgatt aaagcagtga ccagcaggaa ctgcccagag   1680
aactggaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaann                 1727

<210> 1164
<211> 1223
<212> DNA
<213> Homo sapiens

<400> 1164
tctgattggt gacgggtgag gcggcccgaa atcgtaggac ttccgaaagc agcggtggcg     60
tttgcttcac tgcttggaag tgtgagtgcg cgaagatgcg aaaggtggtt ttgatcaccg    120
gggctagcag tggcattggc ctggccctct gcaagcggct gctggcggaa gatgatgagc    180
ttcatctgtg tttggcgtgc aggaacatga gcaaggcaga agctgtctgt gctgctctgc    240
tggcctctca ccccactgct gaggtcacca ttgtccaggt ggatgtcagc aacctgcagt    300
cggtcttccg ggcctccaag gaacttaagc aaaggtttca gagattagac tgtatatatc    360
taaatgctgg gatcatgcct aatccacaac taaatatcaa agcacttttc tttggcctct    420
tttcaagaaa agtgattcat atgttctcca cagctgaagg cctgctgacc cagggtgata    480
agatcactgc tgatggactt caggaggtgt ttgagaccaa tgtctttggc cattttatcc    540
tgattcggga actggagcct ctcctctgtc acagtgacaa tccatctcag ctcatctgga    600
catcatctcg cagtgcaagg aaatctaatt tcagcctcga ggacttccag cacagcaaag    660
gcaaggaacc ctacagctct tccaaatatg ccactgacct tttgagtgtg gctttgaaca    720
ggaacttcaa ccagcagggt ctctattcca atgtggcctg tccaggtaca gcattgacca    780
atttgacata tggaattctg cctccgttta tatggacgct gttgatgccg gcaatattgc    840
tacttcgctt ttttgcaaat gcattcactt tgacaccata taatggaaca gaagctctgg    900
tatggctttt ccaccaaaag sctgaatcty tcaatcctct gatcaaatat ctgagtgcca    960
ccactggctt tggaagaaat tacattatga cccagaagat ggacctagat gaagacactg   1020
ctgaaaaatt ttatcaaaag ttactggaac tggaaaagcm cwttagggtc amtattcaaa   1080
aaacagataa tcaggccagg ctcagtggct catgcctata attccagcac tttgggaggc   1140
caaggcagaa ggatcacttg agaccaggag ttcaagacca gcctgagaaa catagtgagc   1200
ccttgtctct acaaaaaaaa aaa                                           1223

<210> 1165
<211> 1249
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1138)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1196)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1202)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1225)
<223> n equals a,t,g, or c

<400> 1165
acgtcccgcg cgtcggcggc cgcggagcag cgcagggagc caggcgggct gccggcgggt     60
gtgaagaaaa aaatgacact ccaatgggct gcagtggcaa cctttcttta tgccgaaata    120
ggactcattt taatcttctg cctacctttt attcctcctc agagatggca gaagattttt    180
tcatttaatg tctggggtaa aattgcaact ttttggaaca aggctttcct taccattatc    240
atcctattga ttgttctatt tctagatgct gtgagagaag taaggaaata ttcctcagtt    300
cataccattg agaagagctc caccagcaga cctgatgcct atgaacacac acagatgaaa    360
ctttttaggt ctcaaagaaa tctttacatt tctggatttt ccctattttt ttggctagtt    420
ttgagacgtc tggttacgct tattactcaa ctggcaaaag aactgtcaaa caaaggtgta    480
cttaaaactc aagcagaaaa tactaacaag gctgccaaaa aatttatgga agaaaacgaa    540
aaactaaaaa ggattttgaa aagccatggt aaagatgaag aatgtgtttt ggaagcagaa    600
aataaaaaac tagtagaaga ccaggagaaa ctgaaaactg aattaaggaa gacttcagat    660
gccctttcta aggcacaaaa tgatgtgatg gaaatgaaga tgcagtcaga gagactttcg    720
aaagaatatg atcaactcct gaaagaacac tctgaacttc aggatcgttt agaaagaggc    780
aacaagaaaa gactgtgaac tttataaaag acacttgcaa tatactgtgt caaaatgata    840
attttgttat gttagcctct agaaaattta agttcagaaa aatgcactat gaccggttcg    900
taattttttt aatgccacac ataggttgta ttgtaatggc attatcaaaa tatttgatga    960
tgtttcagat atattgcaaa gtctgtattc cagctcttaa gaaaaatata agcatgttaa   1020
ataccatatt tacatattga taatgtcatt ggtatatggt ggctgtttac caataaaagg   1080
aaaaaattca ttaaccggtt gcttccaaaa ttaggaagwt ytamgttgca tgaaaccntt   1140
aataggcctt ggaaagcttt ggattaaggt tttccaggta attaataacc cctttnaatt   1200
cnggatggat ggtgtgtttg gaaanaggtg ttccatttcc ggccaattt               1249

<210> 1166
<211> 455
<212> DNA
<213> Homo sapiens

<400> 1166
gcagatccct atcatcttgg gaaacagtag cccagaggtt caggaagatg ttaacttaaa     60
tgttcggggt gccccagtct gttcagcatg gctraaatcc acactccgta ttcttccttg    120
aagaaactgt tatctttact caatggcttc gtggctgtgt ctggcatcat cctagttggc    180
ctgggcattg gtggtaaatg tggaggggcc tctctgacga atgtcctcgg gctgtcctcc    240
gcatacctcc ttcacgttgg caacctgtgc ctggtgatgg gatgcatcac ggtactgctt    300
ggctgtgccg ggtggtatgg agcgactaaa gagagcagag gcacgctctt gtttgttgga    360
gatgtggcct tggaacacac cttcgtgacc ctgaggaaga attacagagg ktacaacgag    420
ccagacgact attctacaca gtggaacttg gtcat                               455

<210> 1167
<211> 2796
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2419)
<223> n equals a,t,g, or c

<400> 1167
acagggctat tgggtacggg ccccccctac gagttttttt tttttttttt tttttttttt     60
tttttttttt tttttttttt tttttttcac tttgcaattt caatgtttat ttctgatacc    120
aaaacttgac agcacacaag gggaaaaaaa gcagtagaca aggaacagca aataaattta    180
tcttgcatgc cactttcagt caacaggatg tggctctcta gatagctgtg tttagaagga    240
atctgaggct tcagcctcac acaggggaaa gactactgcg attgatagca atatccaaca    300
tctcactcaa cccagaagaa accaatggca ccaaagttgg cagcgaagtt ggcactggct    360
gtaccaccag gaccaataat gggaccggca aaggtctgag ggaatctgga gcgggcattc    420
tggtggtatc tggcccagaa ggtaaatgga attctggacc agggatctcc aaaatctcct    480
tcctcatccc aggtcagcag ctcaaactca atgtcatccc agctccaggg cccagacaca    540
gcctcatctc caattcccat gcgggttctt gcttcagccc gggcttcggc ctcagctgca    600
gcagcatcca gagcatccaa ggcctcatct gcagcctcca tgaactgtgc agtccagtca    660
cgagggtctc ttttctgaac ctctgcaatg aatctcagca ctttcatctt gctagtctca    720
tggtaggaac ggaggcccca gaggaactca tactccgggg ggttgctgtt gggcactcgt    780
ctgtagtcca ggtatttctg ctttacaaac tcataggtga gaagtttcct tagatctcca    840
aggaggggat gtctcacccc aggacgcagt cccatcttgc gtagtgcctc ccagaggaca    900
gcctcactgg cacggttgcc attcatgaag atgacaccca gaatcaccaa gaggagaccg    960
agcttgggtg tgtctttggt cgttcccagt atgccagcca gggactcggg ggtactgatg   1020
agaatataca ggtgttcttc tttgtcaatt tctttcagtt gaatcccaaa tttcttctct   1080
aggacaaagc atgcacgttc aatgatttct ggataaacat cagtgtattc acggatgata   1140
tctctcagca tttctgagcg cttgatgggc acctttgtgt agtccttaag catcaagtac   1200
ttgaccaact tatttgctct ttcctgaaga agggccacat ctcggggctg tgcagcacct   1260
gggttctgtg aggcacgcga gttgggagaa gggcgcaggt taggcgaggg gcgcaggttc   1320
tgccagtcag gtggaattgg ccaatcagcg gggatccagt caggtggtag tggccagtca   1380
gtgggaagtg gccaatcagg tggcagtggc cagtcgggtg gtagcggcca gtcaggagga   1440
ccttgccagt ctggaggacc ctgccagccc ggtggggtct gccatccagg tggagtctgc   1500
catccaggtg gattctgcca ggccagtgga ttcggccaga caacagggcc gggccagaca   1560
atggggtttg gccagatcac tgggttctgc cagattactg ggtttggcca aatcactggg   1620
ttctgccaag cgactgggtt ctgccaggct ggtggggtct gcctagctgg agggctctga   1680
cgtgctggtg gggtctgcct ggctgtctgg ttttgccagc ctgaggggtt ctgccaagcc   1740
aatggcgtct gccagagcac attggggggt gcgccaggtg ggttctgagt ggtcactgga   1800
actggtgcag acctccaggt ccctgcagcc agtggggccc gcctctgatc cccactgctg   1860
ttctcttcaa cattcaagtt attaatcttg cgggtcctct tgccccgaat tattgtccgg   1920
gactccagat tctgagcctg ggaaccatct gctgatgtct gtgcagttgc accgtcaggt   1980
tcagagatac ctgggtcggt ctctatgtca gcctgggaag tggccatttt ggcctgattt   2040
acattctggg tctgggtatc agctgttggg gccttagtgg tatcattcca agccttgaaa   2100
ggggtcttag gcctgctgtt ggccaggtca ttggcattga gagactgaga gaaattgtag   2160
gtggcatttg ggcccacttt agtagtggca ttctgggcct tgaaggccat ctcagacttg   2220
ttagcagcta actcaccagt ggttgctgcc tgggaaaaat cataggcagc atttggaccc   2280
tttggggtag cattttggga cttaaaggct gccttgggct gcgtgttggg cacatccttg   2340
gcattatgag cctgagagaa atcatagaca ccatttgggc cttttgtggt ggcattctgg   2400
actttaaagg ctgacttang cctagcggca gctgctgaaa cctgaatgtc agccatctca   2460
ttggcagttg ggggctgtga actctgggga ctagcagctg cggtggcctg gttagtaggt   2520
ggagcctctg agatctggat ggcctccatc aaggtctgca taagcaaggc gctgtcttct   2580
acggaggcct cagcctggaa gccgaggagg cccgcaccac agtccatttt ctgagccatg   2640
gctcctgtcc ctctggcaag agcggagcct gggggcttgc ctcaggcccc aaccccaacc   2700
ccctcgctgc ctcccttctt cacgactcag aggatcggga ttgctgggct cggctctcag   2760
cagccgcact ctctccttgt ccaggagaaa atgccc                             2796

<210> 1168
<211> 680
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (267)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (357)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<400> 1168
agcagaccct gtccagccag gagcgcatgg aggaggactc cttgctggct gccttgcacc     60
ggcagttcct gatgtgggcc cagtcccctt tgtkaagagc actgaccctt cttccagcta    120
ctttgtcatc ttgaactctg ctgccttctt taaggtggga agccagcttg aggtgctggt    180
tcatgtgcag gattttcaaa gaaagcccaa gaagtatggt ggrgactacc tgcaggccag    240
aattcactcc ctcaagctgc agstggngyt gtgggcaggg tggtggrtta ccagaatggg    300
ttttacaagg ttttctttac tttgctakgg cmaggcaaag ttaaagtatc cgtatcnctg    360
gtccacccca gtgaagggat cagagttctt cagcgcttac aggaagataa accagacagg    420
gtctatttca agagtctctt ccgttcagga agaatttctg aaactactga gtgcaacgtg    480
tgtcttcctg ggaatctgcc cctgtgtaac tttacagacc tctacactgg ggagccctgg    540
ttctgcttca aaccaaagaa gctcccttgc agcagcagaa ttacccattt caaaggtgga    600
tacctgaaag gtctcctaac cgctgcagag agtgctttct tccagagtgg tgtcaatatc    660
aaaatgccag tcaactccan                                                680

<210> 1169
<211> 1566
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (577)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (723)
<223> n equals a,t,g, or c

<400> 1169
aantaantna ggaaaggtgt tgcagcacag gcagttttct tctccttctg ctcccctgtt     60
tctcataccc ccaaactcag atgctggagc tcaggcccgc cgtgtgtgca cccaggcagg    120
agcgggcgct gtccaggctg ggccgccccc ttggctctcc ctcctgttcc aggggagcca    180
taggagggaa agcaggtggc ccggggggga tatgggggcc ccagccctgt cccaaagctc    240
cctgctcggc tgcccctcgc ccgcctttat ataaattctc tgaatcacct ttgcatagaa    300
aataaaagtg tttgctttgt aagaaaagtc tggaaagtag cagaatcatc tcaaggtgtc    360
aaaggagcct tcagtcatcg tctggggggc aggacaggca gaggggttgg tccacttagg    420
tgttgcctgt gggacccggg ccttcctagg agggggccag ggactgcggc aaggtagggg    480
acagcgcgat gtttgagggc agagatgtga tttggggtgg aggagccacg ttctccggag    540
gcagcgactg gaagaagtac aacttacagc ccatggncag gagggcgtgg agcagcacga    600
ccacggacag cagcactgtg gccaccagcc tggtgtcctc acggaccacg ggccagaggg    660
tgawtaccag cccggyggyt gacaggccca gggccagcgc ccccaaagag ccactgtagc    720
canaggcaca gggaatgagc cacaggacca ccatggggat gaagacaaag agggagtagc    780
cgtagatgca cacagtctcc aggaaggtgt agggccccat gcgctcctgg acacccttgc    840
gccaccgcag gaagccccac agggccaggg gcaccagcca cgtatagcag tagatgctga    900
tgcctgccac ggtcaccttg tggaactggg ggctgtagtg gatggagggg tccctcctct    960
gggccagcac cagcgtcagg ttgccagtga cggccaggac aaaggccaac gtggcacaga   1020
tccagaaggg gccatacaga tccggccgat tccgsaratg gtgccgcaca aagttgtggc   1080
caggccgggg cagcagtgag cctttgatcc ggtccaggac ctgtgaggtg tccacgtcaa   1140
agaagctctg atagtagctg aaggtccaga atcccggctg ctgctgctgc tgctgctcct   1200
gcaggagcgc ggccttgtca ctctcctcct ccacctcatc ctcggctcca tagctgccac   1260
ctgarcccac ggccacagcc acgtgccctt gtggggtcag ctgatcgctt ctgctggtgg   1320
tggctgcatc tggggtgtca gccagaagat tagtggcctc ctcgaattca tggaaggtca   1380
gctcgtcggc cgatgccatg gtcgttcagg ggcgtctccg catccctcgc tggcgaccaa   1440
ctgcacccac ggaggcttga actcgtcgtc ccgtccccac aggtgcgtcc gccccccctc   1500
acctgmrgcc acctgggccg gcgtggctgg gctctactgc ctgccgtctc gcctacccgt   1560
cagact                                                              1566

<210> 1170
<211> 1485
<212> DNA
<213> Homo sapiens

<400> 1170
gatcaaaccg gacacaaggt gctgtgctcc atcatcgccg gtaccttgca ctatctctac     60
ctggccacct tcacctggat gctgctggag gccctgtacc tcttcctcac tgcacggaac    120
ctgacggtgg tcaactactc aagcatcaac agattcatga agaagctcat gttccctgtg    180
ggctacggag tcccagctgt gacagtggcc atttctgcag cctccaggcc tcacctttat    240
ggaacacctt cccgctgctg gctccaacca gaaaagggaw ttawatgggg cttccttgga    300
cctgyctgcg ccatcttctc tgtgaattta gttctctttc tggtgactct ctggattttg    360
aaaaacagac tctcctccct caatagtgaa gtgtccaccc tccggaacac aaggatgctg    420
gcatttaaag cgacagtcag ctgttcatcc tgggctgcac gtggtgtctg ggcatcttgc    480
aggtgggtcc ggctgcccgg gtcatggcct acctcttcac catcatcaac agcctgcagg    540
gtgtcttcat cttcctggtg tactgcctcc tcagccagca ggtccgggag caatatggga    600
aatggtccaa agggatcagg aaattgaaaa ctgagtctga gatgcacaca ctctccagca    660
gtgctaaggc tgacacctcc aaacccagca cggttaacta gaaaaatctt ctgaataaga    720
tyttccctct ttgcccgtgg aaaatctgaa caatctttga gccatctaga ggggaaagaa    780
aagactttgt tctgtgtgtt tcaagaaatt caccatgtca gcaatatgaa ggatgttatg    840
gaaggcgtgc ttggcattca attcctgcag aaaccggaaa tcttccaygc cctgcaatgt    900
gctcatcaaa ctctcagcat atggacggcc agctgtggcc catatcttgg ycactctgaa    960
gcacamtatt tatgaagcta tagaacgtta agacctcttt cacagcctct ccttcctaca   1020
aagactcctc caaatcttaa aatgaagcag gaaaacgagc ctaagaggac tttcataccg   1080
acaacatctg aaaggactag aatgttcaca ccacgatctg gatttcttaa ttttttgttt   1140
ttgtttttgt tgttctctag ttctacgggt ttgattattt agtcatgtga aaaatattga   1200
ttactcacac atagatcaag agagacrcgg ctcctgcctt catggagctt ttaggggaaa   1260
atgaagtggc tcttgcagct agagttgact cagaagccga aattcctaga aatcaggttt   1320
ctactgctag gcaattgaag tataaactat tttataaaca ctgtcttctt tcatcttcac   1380
accaacatgc agaaaagttt ctaatctcag atcagggatg tgcaacaaat tccatttcaa   1440
aggaatgacc tgcaaaactc ctaaatattc caagcaaatg ccctt                   1485

<210> 1171
<211> 1275
<212> DNA
<213> Homo sapiens

<400> 1171
ctcgagtttt tttttttttt tttttttttt tttttttagt tcaacctcat tttaatgaca     60
tatacaatgt gctcatttta gcattatatg tagtggccag aaactgtgcc aaatatcaaa    120
ataaattgtg gtatgtttat acaacagaat acagcaatga caatggatga actaatggta    180
cacacaattt gtggattaac cttataactg tcaggtaaat aatccacaca cacaagtgca    240
taatgtataa atccatttat ataaagttca aaaacaggca aaatgaatca aaggtgatga    300
aactcagaaa aactgctatg tttgggaggt aatggctgag aaaaggcagg aatgaggctg    360
tgaagtgttg ccaatattct acatcttcac tttggcagtg gttacacagg tgttcacgac    420
ataaatatct atcagactgt atacagtttt gtccactttt tgaatgcatg gtatacttca    480
gtaaaagttt actaaaaaat aaaaataaaa aagacattgt gcttcttgtt accaaaataa    540
aaccatggca gatattttgg taaatattct atttttccca tcttctactg ttgctgatga    600
cagggatggt attcaggtga acactttgtc acttagaata tcatttagct ttagcctgtg    660
cagccaatgc agcttcttca cgccacttag ctttctttgc caagttccaa cttgttaagg    720
attcatgtcg ttctacagcc cttttggctg acactatcac agcaaagcag gcgataattg    780
tgagtccaat cattatgtaa caagctttca ctcgagcttt gtttcttgcg gtgtctatca    840
tttctggcgg gatccgaggc gggatctcct ccatcgattt gaaacgccct gtccacagca    900
ggattttctt gtcgaactgc gaaggcctgc gctgcgtggg gactcggtga atctccccgt    960
gaccttgggg cccagaattg ctgggggccc cgccgctgga gtagcagggg agaccccggg   1020
gcggaagagc cggtgcgggc cgtcgcgtgg cctcgagagg cgccccgggg ccgcagcgga   1080
ctgttagccc gcggccaagg cgcagtaggc tcccgaccgc cctgagcatg ctgcccgctt   1140
gtcccgcgcc gcacccgcac tccggaccca gccacaggcg ttgtccccgc agctctcctc   1200
gtcccgcccc ggcctgccgc gcgctggaga gcctgggacg tgcagctgga acccctggcg   1260
ctcgcacact cagct                                                    1275

<210> 1172
<211> 777
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (699)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (754)
<223> n equals a,t,g, or c

<400> 1172
gggcatggct gacgacgcgg gtttggagac cccgctgtgt tccgagcagt tcggctccgg     60
ggaggcacgg ggctgccgcg ccgccgcgga cgggagcctg cagtgggagg tcgggggctg    120
gcgctggtgg gggctctcca gggccttcac ggtcaaacct gaaggacgag atgcgggcga    180
agtgggggct tccggggccc cctcaccgcc cctctccggg ctccaggccg tgttcctgcc    240
tcasggcttc cctgatagcg tcagcccgga ctacttgccc taccagctgt gggattccgt    300
gcaggcgttt gcttccagcc tctccggctc cctagccacc caggcagtct tgctgggcat    360
aggggtgggg aacgcaaaag ccactgtttc agctgccacg gccacctggc tcgtraaaga    420
ttcaactggc atgctgggcc gcatcgtctt tgcctggtgg aaagggagca aactggactg    480
caatgccaag cagtggaggc tttttgcgga catcctcaat gacgtagcca tgttccttga    540
gattatggct cctgtatacc caatctgttt caccatgacc gtstccacca gcaacctarc    600
caagtgcatc gtgagtgttg ctggtkgggc cactcggctg ccctgaccgt gcaccaggct    660
cggaggaaca acatggctga cgtgtcacaa ggacagcanc caggagacgc tggtgaacct    720
ggcggggctc ttggtcagcc tcctgatgct cctntggtgt caagttgccc tggctta       777

<210> 1173
<211> 1410
<212> DNA
<213> Homo sapiens

<400> 1173
aatagccatc caccacatgg ccaaataaac catgacagga ccaattgcca gtcagcaatg     60
agaagcagct aactgttgac atgccaaaag cttgcacggg cctcaaggtt gtcatgcggc    120
atgaaagaca ctcatctcag gccacacagg attccattta tccaacattc ctgagacaac    180
agaattctgg tgatggagca aaggtcagcg gtggccaggg gctgggtgtg gctatgaagg    240
ggtggctgcc ttgtgatgat tcaatatgct atgtttttcc tttgtggttt tctgtatcta    300
tgttttatct tatttttttt gagctctgtc acccaggctg gaatcagtgg cacgatcttg    360
gctcactgca acctccacct cctgggttca agcaattctc ctgcctcagc tgcccaagta    420
gctgcgacta caggcatgcg ccaccatgtc cggctaattt ttgtactttt ttttgagaca    480
gagtttcgtt cttgttgccc aggctggagt gcaatgccgc aatctcggct cactacaacc    540
cccacctcct gggttcaaga gattctcctg cctcagcctc ccgagtagct gggattacag    600
gcgcccactg ccacaccccg ctaatttttg tatttttagt aaagatggag ttgcaccatg    660
ttggccaggc tggtctcaaa ctcctgacct caggtgatcc acccgcctca gcctcccata    720
gtgctgggat tacaggcatg agccaccatg cccggcccaa tttttgtatt tttagtagag    780
acacggtttc accatattgg ccaggctggt ctcgaacttc tgacctcgga tccacccgcc    840
tcagcctccc aaagtgctgg gattacaggt gtgagccact gcgcctggcc ctgtcaagta    900
ttctttgagg actgggcacc aggtccttgt gaagcaggta gtgtgtgtya cctattggac    960
aaatgcccaa caaccccacr acacatgtta ttgttgttga agtgcttgat ttacagacag   1020
ggaaaccgag gctaaagaag gttaacggac ctcatgtcta agactgcaga atgggtgagt   1080
caggatttga acccacaccc acgttttcac tttgtctgtg caggaagggt atctgggctg   1140
tgagggggag gagggtgccc ttctcatacc aacaaatagc tccggtggcc ctggggggac   1200
tccttggcca tcagggtctc cgccagcgcc tygtacagct catccaaagg ttccgtgtgg   1260
acagcctcgt gctgggggca gacagagtga gagcttgttt gctttwgttc taatcygtaa   1320
mmatggccag atgattttca ccaagtttgc aggggagatt tgggatggaa tggtgtgata   1380
ccagccagct tgcatataaa atattcactt                                    1410

<210> 1174
<211> 1812
<212> DNA
<213> Homo sapiens

<400> 1174
ggcaggcacg aggtggccta gagatgctgc tgccgcggtt gcagttgtcg cgcacgcctc     60
tgcccgccag cccgctccac cgccgtagcg cccgagtgtc ggggggcgca cccgagtcgg    120
gccatgaggc cgggaaccgc gctacaggcc gtgctgctgg ccgtgctgct ggtggggctg    180
cgggccgcga cgggtcgcct gctgagtggg cagccagtct gccggggagg gacacagagg    240
ccttgttata aagtcattta cttccatgat acttctcgaa gactgaactt tgaggaagcc    300
aaagaagcct gcaggaggga tggaggccag ctagtcagca tcgagtctga agatgaacag    360
aaactgatag aaaagttcat tgaaaacctc ttgccatctg atggtgactt ctggattggg    420
ctcaggaggc gtgaggagaa acaaagcaat agcacagcct gccaggacct ttatgcttgg    480
actgatggca gcatatcaca atttaggaac tggtatgtgg atgagccgtc ctgcggcagc    540
gaggtctgcg tggtcatgta ccatcagcca tcggcacccg ctggcatcgg aggcccctac    600
atgttccagt ggaatgatga ccggtgcaac atgaagaaca atttcatttg caaatattct    660
gatgagaaac cagcagttcc ttctagagaa gctgaaggtg aggaaacaga gctgacaaca    720
cctgtacttc cagaagaaac acaggaagaa gatgccaaaa aaacatttaa agaaagtaga    780
gaagctgcct tgaatctggc ctacatccta atccccagca ttccccttct cctcctcctt    840
gtggtcacca cagttgtatg ttgggtttgg atctgtagaa aaagaaaacg ggagcagcca    900
gaccctagca caaagaagca acacaccatc tggccctctc ctcaccaggg aaacagcccg    960
gacctagagg tctacaatgt cataagaaaa caaagcgaag ctgacttagc tgagacccgg   1020
ccagacctga agaatatttc attccgagtg tgttcgggag aagccactcc cgatgacatg   1080
tcttgtgact atgacaacat ggctgtgaac ccatcagaaa gtgggtttgt gactctggtg   1140
agcgtggaga gtggatttgt gaccaatgac atttatgagt tctccccaga ccaaatgggg   1200
aggagtaagg agtctggatg ggtggaaaat gaaatatatg gttattagga catataaaaa   1260
actgaaactg acaacaatgg aaaagaaatg ataagcaaaa tcctcttatt ttctataagg   1320
aaaatacaca gaaggtctat gaacaagctt agatcaggtc ctgtggatga gcatgtggtc   1380
cccacgacct cctgttggac ccccacgttt tggctgtatc ctttatccca gccagtcatc   1440
cagctcgacc ttatgagaag gtaccttgcc caggtctggc acatagtaga gtctcaataa   1500
atgtcacttg gttggttgta tctaactttt aagggacaga gctttacctg gcagtgataa   1560
agatgggctg tggagcttgg aaaaccacct ctgttttcct tgctctatac agcagcacat   1620
attatcatac agacagaaaa tccagaatct tttcaaagcc cacatatggt agcacaggtt   1680
ggcctgtgca tcggcaattc tcatatctgt ttttttcaaa gaataaaatc aaataaagag   1740
caggaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1800
aaaaaaaaaa aa                                                       1812

<210> 1175
<211> 647
<212> DNA
<213> Homo sapiens

<400> 1175
gcggccgcct ggcacacact ggtcccctgg cacaggtaac aacagaggac cctcagggag     60
agaaggctcc cagcttcctc tacaccctga gaaccgaagc ctcggctcat ctccggccga    120
cgcttcacct tggccttgaa caccacctgg gcaaagtaga ggttcataag cgtcaaggtg    180
aagaactgca ggcagacggg gcagcagtag agaagccaga agggcaaggg ccccaggcgg    240
ttggcgcggg gagtatctcg gaagtagaag gagaagaggg tggtacgcaa ggcggcccag    300
agcagacaga gggccaggaa caccgtctga tagctgagac gcttgtgccc atacagaagc    360
accagccaga gctgggcata gacggagaag aagagcaggg catacagggt ggtgtaggca    420
gctgtcagcc ccagggtcac agcaggtggc agcgcaggca ccagcccggc agcaggcacc    480
aggccagaca ggttactctc catgtcaggg agggaggcct ggccggccgc ctgccaggcg    540
tgaagccccc acgggcctac ggtcctccct caccgggtcc ccggccctcc tcccgcgccc    600
gggcagccat cccagccagg gaggaggttc ccggacgcgt gggtcga                  647

<210> 1176
<211> 2007
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1973)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1994)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2005)
<223> n equals a,t,g, or c

<400> 1176
gatcacccct ttgtttgcca tttcctacag gtgaaacgcc atcattagga ttcactgtaa     60
cgttagtgct attaaactca ctagcatttt tattaatggc cgttatctac actaagctat    120
actgcaactt ggaaaaagag gacctctcag aaaactcaca atctagcatg attaagcatg    180
tcgcttggct aatcttcacc aattgcatct ttttctgccc tgtggcgttt ttttcatttg    240
caccattgat cactgcaatc tctatcagcc ccgaaataat gaagtctgtt actctgatat    300
tttttccatt gcctgcttgc ctgaatccag tcctgtatgt tttcttcaac ccaaagttta    360
aagaagactg gaagttactg aagcgacgtg ttaccaagaa aagtggatca gtttcagttt    420
ccatcagtag ccaaggtggt tgtctggaac aggatttcta ctacgactgt ggcatgtact    480
cacatttgca gggcaacctg actgtttgcg actgctgcga atcgtttctt ttaacaaagc    540
cagtatcatg caaacacttg ataaaatcac acagctgtcc tgcattggca gtggcttctt    600
gccaaagacc tgagggctac tggtccgact gtggcacaca gtgcggccca ctctgattat    660
gcagatgaag aagattcctt tgtctcagac agttctgacc aggtgcaggc ctgtggacga    720
gcctgcttct accagagtag aggattccct ttggtgcgct atgcttacaa tctaccaaga    780
gttaaagact gaactactgt gtgtgtaacc gtttcccccg tcaaccaaaa tcagtgttta    840
tagagtgaac cctattctca tctttcatct gggaagcact tctgtaatca ctgcctggtg    900
tcacttagaa gaaggagagg tggcagttta tttctcaaac cagtcatttt caaagaacag    960
gtgcctaaat tataaattgg tgaaaaatgc aatgtccaag caatgtatga tctgtttgaa   1020
acaaatatat gacttgaaaa ggatcttagg tgtagtagag caatataatg ttagtttttt   1080
ctgatccata agaagcaaat ttatacctat ttgtgtatta agcacaagat aaagaacagc   1140
tgttaatatt ttttaaaaat ctattttaaa atgtgatttt ctataactga agaaaatatc   1200
ttgctaattt tacctaatgt ttcatcctta atctcaggac aacttactgc agggccaaaa   1260
aagggactgt cccagctaga actgtgagag tatacatagg cattacttta ttatgttttc   1320
acttgccatc cttgacataa gagaactata aattttgttt aagcaattta taaatctaaa   1380
acctgaagat gtttttaaaa caatattaac agctgttagg ttaaaaaaat agctggacat   1440
ttgttttcag tcattataca ttgctttggt ccaatcagta attttttctt aagtgttttg   1500
tgattacact actagaaaaa aagtaaaagg ctaattgctg tgtgggttta gtcgatttgg   1560
ctaaactact aactaatgtg ggggtttaat agtatctgag ggatttggtg gcttcatgta   1620
atgttctcat taatgaatac ttcctaatat cgttggctct actaatattt tccaatttgc   1680
tgggatgtca cctagcaata gcttggatta tatagaaagt aaactgtggt caatacttgc   1740
atttaattag acgaaacggg gagtaattat gacacgaagt acttatgttt atttcttagt   1800
gagctggatt atcttgaacc tgtgctatta aatggaaatt tccatacatc ttccccatac   1860
tattttttat aaaagagcct attcaatagc tcagaggttg aactctggtt aaacaagata   1920
atatgttatt aataaaaata gaagaagaaa gaataaagct tagtcctgtg gsnttaattt   1980
ggcaaaattt tacngaagtc tttcngt                                       2007

<210> 1177
<211> 1118
<212> DNA
<213> Homo sapiens

<400> 1177
ggaaccgtgt taagacccag cacccctatt cccaggagct tctggcctga ccatctgcag     60
ccaaagcact aacagggaca gatatgggaa tgtccacctt tgatccgcat cctkcacaat    120
agtggtccca ccatggctgc cactttttta tactatttgg agaaaagacc ttgtataaat    180
tcgaggcccg artgactaac gtctctgtca cacggaaatg ggtacttggt ggcatagaga    240
aacacaatta gccacttttt cagctacact tctcactcag ctgcacccta cacttctcac    300
tcaggtgcac ccccttctgc tgtcctttcc ccaacgtact gggtcccgag cgtggtgggt    360
atttgccaca ctgggtgcca gctcagcagc cccccacctc tctttattct ctccaaagct    420
ggtctttctg actatcattg tggtaggggg aggacagatg ctaaaggtgg aagctgacct    480
ggagaaagag acacacgggg tgactgtggc aaaggacagc tggaaaagaa actctatcac    540
ttcttcattg gcaaccacaa ggcacctgag gccatggcac tcccaraggc tgtgcgcaga    600
gccaagcctc tcaacctctt ctggccctgc gtcctgcagc gaagtctctg ctgtaagaca    660
gtagactcct tcgatgaggt gctcaaaaat gctacccggg gtggtggtgt ctggcttgca    720
gtctggccca gttcagagaa agttgcagag atcaggggcc aaggatgtca tagccccagg    780
ttgtcctcag ggtcccaatc ctagggcagg gtgtgcatgg aagcaagaac tatggaaacc    840
tagctccagt ctgcaggctc tgagccccta gttcctcact ccagcggggc tccctcactg    900
cacagaaccc accccttctg tgtgggcact gctgaccaca sagatgaccc agacccaaag    960
agcctggcag aagctctgtg gttggagctg ggctccgtct ccaggtctgg ttcaggggga   1020
tcaggaaggc tcttttccac ctgtggcttc actggccctt tgagatttcc tatctcaccg   1080
ttacttcagt tacccttgca gggggccagg gagtcaac                           1118

<210> 1178
<211> 1317
<212> DNA
<213> Homo sapiens

<400> 1178
agggcagggt tcagaaagac tgaatgtaaa gctgggctct gagtctgcca ggcccttcgt     60
gtgttgctct gcacattaat taaagggtct acgaggtcag caaggacgcc caagaagact    120
cagtcatgaa aggtgaactg ctcctgtttt ccagtgtgat tgtcctgctc caggtggtat    180
gcagctgccc ggacaagtgt tactgtcagt catctacaaa ttttgtagac tgcagccagc    240
agggtctggc cgaaatccct tcccatttac ctcctcagac tcgaacgctg catttacaag    300
ataatcagat acaccatctt cctgcttttg catttaggtc agtgccatgg ctcatgacct    360
taaacttgtc caacaattcc ctttcaaatc tggcccctgg agctttccat gggcttcagc    420
acttgcaggt tttaaatcta acccagaatt cactcctttc cctggaaagc agacttttcc    480
attccctccc tcagctgagg gagcttgatt tgtcatcaaa caacataagc caccttccca    540
catccttggg agagacttgg gagaacctaa ctatacttgc ggttcaacaa aaccagcttc    600
agcagcttga tcgagcgctc ctggaatcca tgcccagtgt gaggctttta cttctcaagg    660
acaacctctg gaaatgcaat tgccacttgc tcggtcttaa actctggctg gagaaatttg    720
tctataaagg gggactaaca gacggcatca tctgtgaatc accagacacc tggaagggaa    780
aggacctcct taggatccct catgagctgt accagccctg ccctcttcct gctcctgatc    840
cagtgtcctc gcaggctcag tggcccggct ctgcccacgg tgtggtcctg aggcctcctg    900
agaaccacaa cgcgggggag cgagaactct tggagtgcga gctcaaaccc aagccaaggc    960
cggccaacct gcgtcatgcc attgccactg tcatcatcac tggcgttgtg tgtgggattg   1020
tgtgtctcat gatgttggca gctgccatct atggctgcac ctatgcggca atcacagccc   1080
agtaccatgg gggacccttg gctcaaacca atgatcctgg gaaggtggaa gaaaaagagc   1140
gatttgacag ctcaccagcc tgagagcttt tgtctcaaat aggattggtc attgcaggcc   1200
agaagatagt gtctgagtag ggctgatgtg tttcctgtta gtctgatttt gcttttgcca   1260
aaagacaaaa aaaaaaaaaa aaaaaaamac tcgagggggg cccgtaccca atcgccg      1317

<210> 1179
<211> 882
<212> DNA
<213> Homo sapiens

<400> 1179
tggagagtca aaggcatctc ccttcattag ctgctctgag catcaagaat tagaagtctt     60
tcagtggaat tgtacaagag tccctttgaa gataataatc ttggctcagt ttgtataaac    120
tgtcaaattt tcaaataata ggtagggggc tttcactagg aaaatcatgt gctcagaaga    180
ggaaatgact cgtagtcagg ttcaggagtt agtggagtat ttggactttg gtactgctgt    240
cttccaaggt agctctaagt tttgatgtgt gggcttctga gtttatattc tgaaaggaaa    300
tacacttctt ttgaacatcc ccactaggtt cttttccatt gtcaataagg agcatcagcc    360
agtgaatctg tttcaggttt ccattctgca gaactcctcc aaagcatgtg ctagtggcaa    420
gacagtggtt cttatgatgt tttcccttaa cttttccttg tatgttcttg ggtggttcct    480
aagggaaagg gaagcacatg atcatgggaa tgatagccca gaacaaaaag aaatcttgtc    540
ttaccacagt gttttatagg agagattggg agaaatcatc ctgttttctc tgtgacctga    600
tttcagaaga gactgatcca aaaattataa cggcagggaa cctagtgcat ttggcactga    660
gatttaaatg caaccagaat tgtcctcaag gcccagccat aaaagcattg tctctctyga    720
ccttctggta tcttgttaga gagcttttca ctgtgaggaa gtgtggaaaa atagctctgt    780
gtgtgtgtgt gtgtgtgtgt gtgtgtaatc tgttaggttg gggataggtt ttctgctagc    840
caatattaaa agagacctgc aataaaaaaa ttaccctgaa aa                       882

<210> 1180
<211> 1562
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<400> 1180
ccccccncgg gntttttttt tttttttttt tttttttytg ggaatgtcac tttatttgga     60
tttggttcgt ggggtggggg tctcagaaca aactagaagg ccttacatag gcagctgggc    120
ccagccagct gggctcctga cccaggactt cattctggcc tgtcccccca aagcatagcc    180
tccaccttct cacccttctc cagaggagtc tcctccaccc ccacaggagc tgtggacagg    240
ccctgcagcc ctagggaagg aggaagggtc ctgcaagtag acactaaggc acagcgcggc    300
ccaggggtca taagggctct tctggcggtg gcatctgctg gggcttccag ctgggcgggg    360
gctccacgca accgctgacc atccagaagt agtttgggtg cacctggccc tgcacggcct    420
cgctaaccat caattcccca tccactgcaa acacaccttt cccatccttg ggctccaagc    480
ggaaggcgac cacgggcaca tataccaagt aggggcattc atactccata tgcctgccct    540
tctccatggc caggaagagg cgcagcagca tggcacgaga cactcccgcc cgcacgtaga    600
acagatgcat gacgccagct gcacagcggc ccatgggtgc agcaaacatc tcactgccca    660
ggtgcgagtg cagcagtgcc aggactagca caaagtcctc gtcgggcacc actgtccagt    720
gagagggcac tggctcctcc agtggcacaa ggtgtgcatc taccgggccc tgctggacca    780
caacggggga ggcaggtgtc ttggaaccca ctcttcctac agggaggtag gccagtcggc    840
cgcggtaggt gcgcagggct gccagacgca ggaaggtgcc cagagtgaag cgcatctccc    900
ccagacgccg atacttctca ctctctaggt ccacatcagc aatgaagccc caggccaggc    960
tgagcacaga gaagaggcgc agccccgaag ccgtgtgcag agacagcagg ttcatgggtg   1020
acagcagccg gcggcacagc aatagcgtgc agttggtcag gaggtcttca ttggtgacct   1080
gctcatagcc agcataatgg ttcaaggaag ctgccagcgc gttgccagag cctgctggga   1140
ggctacacag gggcttctgg atggcggtct cccagtcagg ccgctccatg agcccgttca   1200
ccacctcgtg catcagcccg tctccagaca tgaccaccag agcgtcccag cggcccagct   1260
cctccgaccg caccagctcc cgcgcgtggt tccgccgctc agtgagcatc agcgtgaagg   1320
agatttcagc ctcagccaaa aggggctgca cgtgactccg gaagagctgc aaggccttgc   1380
ccttgccgcc gcgcgggttc agcagcacca gcacgcggca gggccgcggg agcacgcccc   1440
gggggccgcc cgctgagaaa acaaaaccaa agaggccacg tccgcaaccg accactaggg   1500
ggccacgggt aacaatgggg cactagtgtg ggaacttggt gcccgaaaca ccccggtaat   1560
tc                                                                  1562

<210> 1181
<211> 1591
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1565)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1576)
<223> n equals a,t,g, or c

<400> 1181
acccacgcgt ccggctgaac taatgactgc cgccataaga agacagagag aactgagtat     60
cctcccaaag gtgacactgg aagcaatgaa caccacagtg atgcaaggct tcaacagatc    120
tgagcggtgc cccaragaca ctcggatagt acagctggta ttcccagccc tctacacagt    180
ggttttcttg accggcatcc tgctgaatac tttggctctg tgggtgtttg ttcacatccc    240
cagctcctcc accttcatca tctacctcaa aaacactttg gtggccgact tgataatgac    300
actcatgctt cctttcaaaa tcctctctga ctcacacctg gcaccctggc agctcagagc    360
ttttgtgtgt cgtttttctt cggtgatatt ttatgagacc atgtatgtgg gcatcgtgct    420
gttagggctc atagcctttg acagattcct caagatcatc agacctttga gaaatatttt    480
tctaaaaaaa cctgtttttg caaaaacggt ctcaatcttc atctggttct ttttgttctt    540
catctccctg ccaaatatga tcttgagcaa caaggaagca acaccatcgt ctgtgaaaaa    600
gtgtgcttcc ttaaaggggc ctctggggct gaaatggcat caaatggtaa ataacatatg    660
ccagtttatt ttctggactg tttttatcct aatgcttgtg ttttatgtgg ttattgcaaa    720
aaagtatatg attcttatag aaagtccaaa agtaaggaca gaaaaaacaa caaaaagctg    780
gaaggcaaag tatttgttgt cgtggctgtc ttctttgtgt gttttgctcc atttcatttc    840
gccagagttc catatactca cagtcaaacc aacaataaga ctgactgtag actgcaaaat    900
caactgttta ttgctaaaga aacaactctc tttttggcag caactaacat ttgtatggat    960
cccttaatat acatattctt atgtaaaaaa ttcacagaaa agctaccatg tatgcaaggg   1020
agaaagacca cagcatcaag ccaagaaaat catagcagtc agacagacaa cataacctta   1080
ggctgacaac tgtacatagg ggtaacttct atttattgat gagacttccg tagataatgt   1140
ggaaatcaaa tttaaccaag aaaaaaagat tggggcaaat gctctcttac attttattat   1200
cctggtgtac agaaaagatt atataaaatt taaatccaca tagatctatt cataagctga   1260
atgaaccatt actaagagaa tgcaacagga tacaaatggc cactagaggt cattatttct   1320
ttctttcttt tttttttttt ttaatttcaa gagcatttca ctttaacatt ttggaaaaga   1380
ctaaggagaa acgtatatcc ctacaaacct cccctccaaa caccttctya cattcttttc   1440
cacaattcac ataacactac tgcttttgtg ccccttaaat gtagatwtgt gctgagagaa   1500
aaaaaaacgc ccaactcttg aagtccattg ctgaaactgc agcccagggg ttgaaaggga   1560
tgcanacttg aaaaantctg aaggaactga a                                  1591

<210> 1182
<211> 1997
<212> DNA
<213> Homo sapiens

<400> 1182
ctgggccgcg ccgaggcagc tggctgactc cagtttagcc gccgccggag aggacgkgcg     60
ccgagccggg gctgcggact tcggcctgcc cctcacctca ctcccgctgc ttgcacctcc    120
cggatggtgc tgactgctcc ctaagcggcg gcggcggcga gtcgtgagga cgcgccgcgg    180
aggctgttcg gggtcgaggc ttcccgtcgc cggcacttcc tcttgcggcg cccgtgcgcg    240
gccggcccgg caggcgggat ggcggccgcg gctccrggga acggccgcgc atcggcgccc    300
cggctgcttc tgctctttct ggttccgctg ctgtgggccc cggctgcggt ccgggccggc    360
ccagatgaag accttagcca ccggaacaaa gaaccgccgg cgccggccca gcagctgcag    420
ccgcagcctg tggctgtgca gggccccgag ccggcccggg tcgagaaaat atttacacca    480
gcagctccag ttcataccaa taaagaagat cctgctaccc aaactaattt gggatttatc    540
catgcatttg tcgctgccat atcagttatt attgtatctg aattgggtga taagacattt    600
tttatagcag ccatcatggc aatgcgctat aaccgcctga ccgtgctggc tggtgcaatg    660
cttgccttgg gactaatgac atgcttgtca gttttgtttg gctatgccac cacagtcatc    720
cccagggtct atacatacta tgtttcaact gtattatttg ccatttttgg cattagaatg    780
cttcgggaag gcttaaagat gagccctgat gagggtcaag aggaactgga agaagttcaa    840
gctgaattaa agaagaaaga tgaagaattt caacgaacca aacttttaaa tggaccggga    900
gatgttgaaa cgggtacaag cataacagta cctcagaaaa agtggttgca ttttatttca    960
cccatttttg ttcaagctct tacattaaca ttcttagcag aatggggtga tcgctctcaa   1020
ctaactacaa ttgtattggc agctagagag gacccctatg gtgtagccgt gggtggaact   1080
gtggggcact gcctgtgcac gggattggca gtaattggag gaagaatgat agcacagaaa   1140
atctctgtca gaactgtgac aatcatagga ggcatcgttt ttttggcgtt tgcattttct   1200
gcactattta taagccctga ttctggtttt taacaagctg tttgttcatc tatatttagt   1260
ttaaaatagg tagtattatc tttctgtaca tagtgtacat tacaactaaa agtgatggaa   1320
aaatactgta ttttgtagca ctgattttgt gagtttgacc cattattatg tctgagatat   1380
aatcattgat tctatttgta acaaggagtt ttaaaagaaa cctgacttct aagtgtgggt   1440
ttttcttctc tccaacataa ttatgttaat atggtcctca tttttctttt ggtgcagaac   1500
cgttgtgcag tggggtctac catgcaattt tctttcagca ctgacccctt tttaaggaat   1560
acaaattttc tccttcatca cttaggtgtt ttaagatgtt taccttaaag tttttcttgg   1620
ggaaagaatg aattaatttc tatttcttaa aacatttccc tgagccagta aacagtagtt   1680
taatcattgg tcttttcaaa actaggtgtt taaaaaaaga gacatatatg atattgctgt   1740
tatatcaata acatggcaca acaagaactg tctgccaggt cattcttcct cttttttttt   1800
taattgggta ggacacccaa tataaaaaca gtcaatattt gacaatgtgg aattaccaaa   1860
ttaaaagaga atactatgaa tgtattcata ttttttctat attgaataaa caatgtaaca   1920
tagataacaa tataaataaa agtggtatga ccagtgaaaa aaaaaaaaaa aaaaaaaaaa   1980
aaaaaaaaag ggcggcc                                                  1997

<210> 1183
<211> 884
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (717)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (816)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (837)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (872)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (874)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (877)
<223> n equals a,t,g, or c

<400> 1183
ctttttaaga agcccttgcg ccntgaattt ggttaaattc ggctggcgcc agatccaggc     60
tcctggaaga accatgtccg gcagctactg gtcatgccag gcacacactg ctgcccaaga    120
ggagctgctg tttgaattat ctgtgaatgt tgggaagagg aatgccagag ctgccggctg    180
aaaattaccc aaccaagaga aatctgcagg atggactttc tggtcctctt cttgttctac    240
ctggcttcgg tgctgatggg tcttgttctt atctgcgtct gctcgaaaac ccatagcttg    300
aaaggcctgg ccaggggagg agcacagata ttttcctgta taattccaga atgtcttcag    360
agagccgtgc atggattgct tcattacctt ttccatacga gaaaccacac cttcattgtc    420
ctgcacctgg tcttgcaagg gatggtttat actgagtaca cctgggaagt atttggctac    480
tgtcaggagc tggagttgtc cttgcattac cttcttctgc cctatctgct gctargtgta    540
aacctgtttt ttttcaccct gacttgtgga accaatcctg gcattataac aaaagcaaat    600
gaattattat ttcttcatgt ttatgaattt gatgaagtga tgttccaaag aacgtgaggt    660
gctctacttg tgattaagga aaccagctcg atccaagcac tgcagtgtgt gtaactngtg    720
tgtgcaccgt ttcgaccatc actgtgtttg ggtgaacact gccatcgggg gcctggaaaa    780
atcaggtact tcctcatcta agtcttgacc ttgaangcct cgggttgcaa ccgtcgncca    840
ttgtgagcac cacttttctg ggccacttgg gngngangtc caga                     884

<210> 1184
<211> 823
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<400> 1184
ntctcaancc canctcccca ntggaagcct tcaaatttta atwacccttc ctacsgtgat     60
gtttaaggcc aggagcattc atttctcaac cttgtatcaa tycaggatcc atcggactag    120
gtttcattag gcaagagagt agttcgttcc tcctctgtgc tgaggatgtt ttgagattta    180
gacctttttc tccttgaata ctccagtaga taaaacaagc ccatggctaa tccacttatc    240
agagcccata gaccttgtat agctgctgcc cattcaaaac caattttctc atacagaaat    300
ccacccagcg ttggtcccat aaaagcacca attgaccaca ttgcactaaa aagacctgat    360
acaagtccca atgtacttaa tccctcttca aacccatttt catgtgcaca actgagaatt    420
tccgggaaag ttggaattat actcattcca gcagagaggc cacttacaac taatatcagc    480
accagcagcc agagctgact tttaatatgc aagattggga caggccctaa gagcatgtag    540
cacccggctg tgattaagtt gccaaacacc agaagccatt tccttagagg tggcctttta    600
tcacttagga gaccaaatag tggtgaagag atggcatagg acagtgccat acccaggaat    660
actagtccca catatccagc tggtaaattg aacttctcca aaacaaagag agacagagta    720
ggatcgagga agccaaaaca cgagctgagt gagttgatga cgaaggctat aaggccaact    780
ttgggtaaag cgatcagttt ccagaatgag tgttcacctg gat                      823

<210> 1185
<211> 1701
<212> DNA
<213> Homo sapiens

<400> 1185
ggaatttttc agctgtctga attttaaccc tctggcggct ttacagtacc ttacgctata     60
ctagccactg aaaatgccgg ttcactttct tcgaatcggc tttcaatgtg tatttcacac    120
aaattaatca acttcccctt ccgaggatct ggcctgaaag gtcggataag atatgttaaa    180
cagtatttta gtcatactct gcttgatcgc tgtaagtgcg ttcttctcga tgtccgagat    240
ctcgcttgcc gcctcacgca aaatcaaact taaactgctg gctgatgaag gcaatataaa    300
tgcccaacgc gttctgaata tgcaggaaaa tcccggcatg ttctttaccg tggtccaaat    360
cggtctgaac gcagtggcga ttctcggcgg tatcgtcggt gatgcggcat tttctccagc    420
ttttcacagc ctgttctccc gctatatgtc ggcagagctc tctgagcaac tgagctttat    480
tctctctttc tcgttagtga ctggcatgtt tatcctgttt gcggatttaa ccccgaaacg    540
catcggtatg attgcgccag aagctgtggc tttgcgtatc atcaacccga tgcgcttctg    600
cctgtacgtt tgcaccccgc tggtgtggtt cttcaacggc ctggcgaaca taatcttccg    660
tattttcaaa ctgccaatgg tacgtaaaga tgacatcact tctgatgaca tctacgcggt    720
agtggaagcc ggtgcgctgg cgggcgtgtt acgtaaacag gaacacgagc tgattgaaaa    780
cgtctttgag ctggaatccc gtaccgttcc gtcttcaatg acaccgcgtg aaaacgtgat    840
ttggtttgat ctccacgaag atgagcaaag cctgaagaat aaggtggcgg aacatccgca    900
ctctaagttc ctcgtctgta atgaagatat tgaccacatc atcggttatg tcgattctaa    960
agacctgctg aaccgcgtgc tggctaacca aagcctggca ctgaacagcg gcgtacaaat   1020
tcgcaacacg ctgattgtgc cggatacgtt aaccctttca gaggcgttgg aaagttttaa   1080
aaccgcaggt gaagacttcg cggtgatcat gaacgagtac gcgctggtgg tggggatcat   1140
caccctcaat gacgtgatga ccacgctgat gggcgatctg gtcggtcagg ggctggaaga   1200
gcagattgtc gcccgtgatg agaactcatg gctgattgac ggcggcaccc caattgacga   1260
cgtcatgcgc gtgctggata ttgacgagtt cccgcagtcg ggcaactacg aaaccatcgg   1320
cggctttatg atgtttatgc tgcgtaagat cccgaaacgc accgattcgg tgaaattcgc   1380
cggctacaaa tttgaagtgg tggatatcga taactaccgc atcgaccagc tgctggtgac   1440
ccggatcgac agcaaggcca ccgccctttc gccaaaactg cctgacgcta aagataaaga   1500
agaaagcgtc gcgtaacccc cagaaacatc aacggctcct gaatcaggag ccgtcttatt   1560
actgcatagc actttttact gcatagcact ttggttaagc catctctgtt tgcagacgca   1620
taacctgacg gttaacttcg gacatcactg acaaatgcag cttatccttc acttttggga   1680
taagaatctt acccttatcg a                                             1701

<210> 1186
<211> 3798
<212> DNA
<213> Homo sapiens

<400> 1186
ccacgcgtcc ggggcttcat acaggaaatc tattgctgtg tcaagttcca gagaaaagct     60
tctgttcgtc caagttacta accaggctaa accacataga cgtgaaggaa ggggctagaa    120
ggaagggagt gccccactgt tgatggggta agaggatcct gtactgagaa gttgaccaga    180
gagggtctca ccatgcgcac agttccttct gtaccagtgt ggaggaaaag tactgagtga    240
agggcagaaa aagagaaaac agaaatgctc tgcccttgga gaactgctaa cctagggcta    300
ctgttgattt tgactatctt cttagtggcc gaagcggagg gtgctgctca accaaacaac    360
tcattaatgc tgcaaactag caaggagaat catgctttag cttcaagcag tttatgtatg    420
gatgaaaaac agattacaca gaactactcg aaagtactcg cagaagttaa cacttcatgg    480
cctgtaaaga tggctacaaa tgctgtgctt tgttgccctc ctatcgcatt aagaaatttg    540
atcataataa catgggaaat aatcctgaga ggccagcctt cctgcacaaa agcctacaag    600
aaagaaacaa atgagaccaa ggaaaccaac tgtactgatg agagaataac ctgggtctcc    660
agacctgatc agaattcgga ccttcagatt cgtaccgtgg ccatcactca tgacgggtat    720
tacagatgca taatggtaac acctgatggg aatttccatc gtggatatca cctccaagtg    780
ttagttacac ctgaagtgac cctgtttcaa aacaggaata gaactgcagt atgcaaggca    840
gttgcaggga agccagctgc gcatatctcc tggatcccag agggcgattg tgccactaag    900
caagaatact ggagcaatgg cacagtgact gttaagagta catgccactg ggaggtccac    960
aatgtgtcta ccgtgaactg ccacgtctcc catttgactg gcaacaagag tctgtacata   1020
gagctacttc ctgttccagg tgccaaaaaa tcagcaaaat tatatattcc atatatcatc   1080
cttactatta ttattttgac catcgtggga ttcatttggt tgttgaaagt caatggctgc   1140
agaaaatata aattgaataa aacagaatct actccagttg ttgaggagga tgaaatgcag   1200
ccctatgcca gctacacaga gaagaacaat cctctctatg atactacaaa caaggtgaag   1260
gcatctgagg cattacaaag tgaagttgac acagacctcc atactttata agttgttgga   1320
ctctagtacc aagaaacaac aacaaacgag atacattata attactgtct gattttctta   1380
cagttctaga atgaagactt atattgaaat taggttttcc aaggttctta gaagacattt   1440
taatggattc tcattcatac ccttgtataa ttggaatttt tgattcttag ctgctaccag   1500
ctagttctct gaagaactga tgttattaca aagaaaatac atgcccatga ccaaatattc   1560
aaattgtgca ggacagtaaa taatgaaaac caaatttcct caagaaataa ctgaagaagg   1620
agcaagtgtg aacagtttct tgtgtatcct ttcagaatat tttaatgtac atatgacatg   1680
tgtatatgcc tatggtatat gtgtcaattt atgtgtcccc ttacatatac atgcacatat   1740
ctttgtcaag gcaccagtgg gaacaataca ctgcattact gttctataca tatgaaaacc   1800
taataatata agtcttagag atcattttat atcatgacaa gtagagctac ctcattcttt   1860
ttaatggtta tataaaattc cattgtatag ttatatcatt atttaattaa aaacaaccct   1920
aatgatggat atttagattc ttttaagttt tgtttatttc ttttaagttt tgtttgtggt   1980
ataaacaata ccacatagaa tgtttcttgt gcatatatct ctttgttttt gagtatatct   2040
gtaggataac tttcttgagt ggaattgtca ggtcaaaggg tttgtgcatt ttactattga   2100
tatatatgtt aaattgtgtc aaatatatat gtcaaattcc ctccaacatt gtttaaatgt   2160
gcctttccct aaatttctat tttaataact gtactattcc tgcttctaca gttgccactt   2220
tctcttttta atcaaccaga ttaaatatga tgtgagatta taataagaat tatactattt   2280
aataaaaatg gatttatatt tttggtcatg tttgtaagag agtgaatgca cgtgtgagaa   2340
cattagcttc ttctgaactc attatatctc cacagaggtg ttgatacttg atgcctaaca   2400
gttttgcaga tgtgctacat tggaattgtg tatttttatg gtgtacattc tattgtgata   2460
tatttattga ataattaatg tctattgacc atataagtgg cgaaaaatgc accatagagg   2520
acatggggta tttatttaca aactatgagc tacataataa gcaagtggcc atgggatggc   2580
atgaccctcc cctccatatt tttgtggagc aaaatattgg caatgtttat gtaaatcatt   2640
gttaatatca tgaaattatt tttaattaaa aacataagtc tatttgctcc atagcagaaa   2700
aaacatgaga agttttttca tcatgataga aattgaaaca aaatatattc attcttcaat   2760
cataccatct gagattttta agacagctat tttgtcttat aagtatattt ttctccctct   2820
agacatttca gttactatgg attttgtcct caaagggacc tttagtctat tttggatgta   2880
aagctaatct aatgacactt ggcacatgat attttgatca agccattttg acttgaccaa   2940
aaagcagtgt ccattaggtt tctgcatata aatattacca agcaatgttc acaatagaca   3000
tcattacact gtccttgaaa tttattaatt cttcatccaa ccctggttga gctgaggctc   3060
atagttaggt tcaagactat ctgtttaaat attactgaaa aacaaagtaa gacagtacta   3120
tgcttacctc ttaacttgat aatgtcaaaa caggcatgtt aaatgacatc atagaaaaga   3180
cttcaagata atttatagaa gttaaattat attgtacaga aaataattgt atgaaaatct   3240
ctactatggg gctggaacat ggttgaacat tagaatgata taaaaaatta tatatattct   3300
ccaaatccac gctagacctg tcaaattaga gaatctagag attagacctg gcgtgtcagc   3360
aaggtcatcc aggaagcaga ggctgagacg gagttaggtg tgattactta catagtcgat   3420
tacattttac aaataacatt ttatatgtct catttactgt gctttctccc catcccattt   3480
tgtatctttt cctttgcttt gctagatttg tcaattttct ctctctttct gtctctctct   3540
ctttcaatat ctctaataat ttgaaagtaa ttcatcataa ctaaatatct attggggtta   3600
tgcttcactt acaaacttct gaaaacggct ttactgagat ataattgata tatttaagtg   3660
tacagtttgt taaattttgc acatatttaa aatgtggact ttggtaaatg ttgacatagt   3720
tttacatctg tgaaaccatc agcataatca agataataaa cttgtccatc accccccaaa   3780
aaaaaaaaaa aaaaaaaa                                                 3798

<210> 1187
<211> 1397
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1356)
<223> n equals a,t,g, or c

<400> 1187
acaatttctc accacccaca ccaaagtcct accactgcct gacaaaagca gagagagggg     60
tgtgtgtgta ctcgcatgtg ttggcgggac caaggcaggg aggtaggata aaagggggag    120
gaaggagaga gtagccaggg aatggtggtc ctcagggctg gggctgcccc gccacgtcct    180
tgtccttcgt gggagtgggt tggtacatgg gctgctgctg ctcctccatg tcctcattag    240
cctcctctgt ccctgagccc cgctccacct cggggtacac gaccacacac atcttctggc    300
tcaccagggt tagcagctca atgaagtcac tgaaacactt gggcttgtgt tgccagtaaa    360
cacccaggaa atagacaggc actcctgtca gcatgatggc caggccaatg ccacacacca    420
ccggctctga ccacaggctg aagaccagca ggaaggccca gaacagcaag tagatgatgg    480
ggaacagcag gttgatcttg atggggcggg ggatatcagg cttcttccag cgaaggacta    540
tctgtccagc aaccgtgacc ccatagaaga ggtagttgat gaagcccacg tagttgatga    600
gtgtgtacat gtcgctggtg accagcatca gcagggtgga gatgcatgtg aagagcaggg    660
ctgggattgg ggtgcagcgc ttcacgtgga tcatggccaa cacactggga aggtggccct    720
ctcgggctcc agcgaagaac agccgagagg aggtgaagag agacccatta actcctccaa    780
atgtggacag ggcaacagaa atgggcatga tccaggccat gactcctagg agcttctctc    840
caaaagtcac agcgacggcg ttgatgccag cagctcctgg ggggacattg cagtgacata    900
agcgacattg gcaaagacat acacaaatgt gaccagtggg atggagatga agatggctct    960
gggaaggttc ttgtagggat caacaagctc ctcagtcacg taattcagaa agttccagcc   1020
tccataggca aaggagccct gaaggaaagc cagtgcgacg aggccgatgt caggttcctg   1080
gaaattctca aatgcattct ttggctccag ccagaagtac tctcctttgc atatctgtac   1140
aatccccatg atgataatca gggccaaggc caggagcttc ccagctgtga agatgtcttg   1200
aacccgggtg gcccaccgca cactggaaca gttgacccat gtgaggagca ataagcagat   1260
tggcagccag gagccgaacc aggactctgg ggggggaaac aggttgggga agaacggctt   1320
cagcacgtag tttggaagaa gggttgaggg gcgatngaca gcctgggttt gggttggggg   1380
tagattcacc aagcaca                                                  1397

<210> 1188
<211> 1600
<212> DNA
<213> Homo sapiens

<400> 1188
ttctgcgtcg gggtcgaagc cggaccgaac tttttttcca ttttttttcg cgatgggaaa     60
aattacctaa tgttagcact ggtgatggtt ggcagtgcgc tggtgatcgc cttagggtta    120
ggtaagctgt ttggctggga tattggcctg acggccggta tgttagcagg ctctatgacg    180
tcgacaccgg ttctggtcgg tgctggcgat acactgcgtc attccggcat ggaaagcagg    240
cagctctcac tggcactgga taatctgagc ctcgggtatg ccttaaccta tttaatcggt    300
ctggtgagtt tgattgttgg tgcgcgttac ttgccgaaat tgcagcatca ggacttacag    360
accagcgccc agcaaatcgc ccgcgaacgt ggcctggaca ctgatgccaa ccgtaaggtt    420
tatttaccgg tgatccgcgc ctatcgcgtc ggcccggaac tggtggcctg gaccgacggc    480
aaaaatctgc gtgaactggg tatttatcga caaaccggct gctacattga acgtattcga    540
cgtaacggga ttctggcaaa tccagacggt gatgccgtgc tacaaatggg cgatgaaata    600
gcgttggtag gctatcccga cgcccatgcc cgactcgatc ccagcttccg taacggtaaa    660
gaagttttcg atcgtgacct tctcgacatg cgtatcgtca ctgaagaagt ggtcgttaaa    720
aaccataacg ctgtaggtaa acgtctcgca caactgaagt tgaccgatca cggttgcttc    780
cttaaccgcg tcattcgtag ccagattgag atgccgatag atgacaacgt cgtgcttaac    840
aaaggtgacg ttttacaagt cagcggcgat gcccgccgcg taaaaaccat cgccgatcgc    900
atcggcttta tctcgattca cagccaggtc actgacctgc tggcattctg cgccttcttt    960
gttattgggc tgatgatcgg gatgatcacc ttccagttca gcacattcag tttcggcatg   1020
gggaacgctg ccgggttgtt attcgccgga attatgctgg gctttatgcg tgctaaccac   1080
ccgaccttcg gttacattcc gcagggtgca ttaagcatgg tgaaagagtt cggcttgatg   1140
gtgtttatgg caggcgttgg tctgagcgcc ggtagcggta ttaataacgg cctgggcgcg   1200
attggcggtc agatgttgat tgccggattg attgtcagtc tggtgcccgt ggctggtgca   1260
tccactgaaa gtcgacgcgg atgcctcggt ggtcgataac gtgccggtac atgtggcgct   1320
gcgcccggaa aaaatcatgc tttgcgaaga gccgcccgcc aatggttgta acttcgcggt   1380
gggggaggtg atacacattg cctatctcgg cgatctttcg gtgtatcacg ttcgtctgaa   1440
aagtgggcag atgattagcg cccagctaca aaacgcccat cgtcatcgta aagggttacc   1500
gacctggggc gacgaagtgc gtttgtgctg ggaagtggac agctgtgtgg tgctgacggt   1560
ttaaggagca aagatgagta cacttgaacc tgctgcccag                         1600

<210> 1189
<211> 1377
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> n equals a,t,g, or c

<400> 1189
cttcctcttc acagacacgc tggacttgaa caaacccagc cttctataca accntggagc     60
cagggcaagg gagagacaga aggagcaagt gacccaggga gacaaacact tggagatact    120
tggggctgag tttgagcaag actccctaac ctgtgtctgg acaagtctga tgtcctgtgt    180
ggcccaagaa gaactgaccc cgtgtctgga gctcccaccg ttattgcatc cctgctgtgg    240
ctcacctgct gctgtctcca ggagcccctg agaagatttg cytcctctcc cctgctaagc    300
tccaggtcct gagattgaat taggggctgg agctcactgc actccagcag tcatgggacc    360
caggataggg ccagcgggtg aggtacccca ggtaccagac aaggaaacca aagccacaat    420
gggcacagaa aacacacctg gaggcaaagc cagcccagac cctcaggacg tgcggccaag    480
tgtgttccat aacatcaagc tgttcgttct gtgccacagc ctgctgcagc tggcgcagct    540
catgatctcc ggctacctaa agagctccat ctccacagtg gagaagcgct tcggcctctc    600
cagccagacg tcggggctgc tggcctcctt caacgaggtg gggaacacag ccttgattgt    660
gtttgtgagc tattttggca gccgggtgca ccgaccccga atgattggct atggggctat    720
ccttgtggcs ctggcgggcc tgctcatgac tctcccgcac ttcatctcgg agccataccg    780
ctacgacaac accagccctg aggatatgcc acaggacttc aaggcttccc tgtgcctgcc    840
cacaacctcg gccccagcct cggccccctc caatggcaac tgctcaagct acacagaaac    900
ccagcatctg agtgtggtgg ggatcatgtt cgtggcacag accctgctgg gcgtgggcgg    960
ggtgcccatt cagccctttg gcatctccta catcgatgac tttgcccaca acagcaactc   1020
gcccctctac ctcgggatcc tgtttgcagt gaccatgatg gggccaggcc tggcctttgg   1080
gctgggcagc ctcatgctgc gcctttatgt ggacattaac cagatgccag aaggtggtat   1140
cagcctgacc ataaaggacc cccgatgggt gggtgcctgg tggctgggtt tcctcatcgc   1200
tgccggtgca gtggccytgg ctgccatccc ctacttcttc ttccccaagg aaatgcccaa   1260
ggaaaaagtg agcttcattt cggcgaaagg tcttagcagt cacagaytca ctgccaggaa   1320
gggaaggayt ytcctytaag agaaccctgg gggatcacga aaagcaggat ggctttc      1377

<210> 1190
<211> 1322
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1132)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1182)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1201)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1281)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1301)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1320)
<223> n equals a,t,g, or c

<400> 1190
gtgcatgcgc tcgcatcatg gcggctgagt gggcttctcg tttctggctt tgggctacgc     60
tgctgattcc tgcggccgcg gtctacgaag accaagtggg caagtttgat tggagacagc    120
aatatgttgg gaaggtcaag tttgcctcct tggaattttc ccctggatcc aagaagttgg    180
ttgtagccac agagaagaat gtgattgcag cattaaattc ccgaactggg gagatcttgt    240
ggcgccatgt tgacaagggc acggcagaag gggctgtgga tgccatgctg ctgcacggac    300
aggatgtgat cactgtgtcc aatggaggcc gaatcatgcg ttcctgggag actaacatcg    360
ggggcctgaa ctgggagata accctggaca gtggcagttt ccaggcactt gggctggttg    420
gcctgcagga gtctgtaagg tacatcgcag tcctgaagaa gactacactt gccctccatc    480
acctctccag tgggcacctc aagtgggtgg aacatctccc agaaagtgac agcatccact    540
accagatggt gtattcttac ggctctgggg tggtgtgggc cctcggagtt gttcccttca    600
gccatgtgaa cattgtcaag tttaatgtgg aagatggaga gattgttcag caggttaggg    660
tttcaactcc gtggctgcag cacctgtctg gagcctgtgg tgtggtggat gargctgtcc    720
tggtgtgtcc tgacccgagc tcacgttccc tccaaacttt ggctctggag acggaatggg    780
agttgagaca gatcccactg cagtctctcg acttagaatt tggaagtgga ttccaacccc    840
gggtcctgcc tacccagccc aacccagtgg acgcttccgg gcccagttct tcctgcactt    900
gtccccaagc cactatgctc tgctgcagta ccattatgga acgctgagtt tgcttaaaaa    960
cttcccacag actgccctag tgagctttgc caccactggg gagaagacgg tggctgcagt   1020
catggcctgt cggaatgaag tgcagaaaac tagcagttct gaagatgggt caatggggga   1080
acttttcgga gaagtctaag ttcaaaggac tcttctggct tgcttcaatc anacctacac   1140
catttaacct aatacctcgt ggaagacagg tcggcgggct gnttggacac cacgataacc   1200
nttaagcctg gaacagaacc gggacttcgg cctgaaccgg ctggattttc cagggggttc   1260
ttgaaaaaag gatgacttca ngggcttacc gggcttttgg nccaaaccag aaggatcatn   1320
gg                                                                  1322

<210> 1191
<211> 1554
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (25)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (39)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1031)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1553)
<223> n equals a,t,g, or c

<400> 1191
ggccgaccat gaatggtcca tgggnttgta aacagtccng gcgctggagt cggtgttgcc     60
gtcgggcgag ttgtcggcac gaarcaaaat gcctatgttc aaccactggt gttaatgaac    120
aaagatactg tgcgtctctg gggaagacgc acctaggtgg cggccactcc catggccttg    180
tctaggactc agagaccact cggctctgag cttccaggcg cctcgtctgt gtgcatctca    240
cgcccgacgt ggcttctgaa acgtgcattc aacctcaaac ttttgcataa aatagaatga    300
atcgttttgc tctgatgaaa tgtaggcctt acttgtatat aagactgttc ctgccttcgg    360
tctgtcattt tcccacctgc ctcccctacc caccccccac ccaccacctg gggcttcctc    420
tgggggtccg agggtcttcc catcacatga agacatcagg ttgggtcctg ccccactgcc    480
cctccccctg ttcctgcccc aagccgtcaa tcagattgtg gagcagtaca cagtcagatg    540
aaaatactgt aaatgcactc attgggggtt ttttggtttt acttcatatc atgtgcaatg    600
ttgtggcttt aacattttat gcaactattt atgaagacct ctgttgtacc tgtaataaat    660
atatagaaaa agcacatact tcgtatggtg agctttatgg ttttgtgtgt gtgttggggt    720
tggcgggtgg gtgggtaggg tcgtagccct gtgccatcgg ttcaaagaga cttttcgtga    780
aatttgttgg ttttgaggac tgtaaaagtg atttcatact ctgaatataa aactggataa    840
tagggtaatg ttttaaaatt tattatgcta ttattcagaa tgccaaagta ttattttttt    900
tcccaaaatc agtctggaca tttactactt tttagacttt ttgacgttga actttctgta    960
taaaaattgg ctgggttttg agcttttggt aagaaataaa agccgattaa gcactggccg   1020
ccccgcgctg ngtacccaat gcccgagtca ctgtggcagc attcgcactg gtgtggggag   1080
tcctttcaac tcaaggaggc tgggtttctg ggcaccctcg aagttttctg gatgtctttt   1140
tatctttctc gtgtgaactg cactacaaaa gagaccagcc cgcttcccaa gccagccaga   1200
cacctgggtc ttgagccata aactggcgta gttaagcttt gcagcttcca gtgtatttta   1260
tttattcttt tgttgggttt ttgtttgttt cttcttgtaa aattgtacag aaacttttta   1320
aaagaaattg gattcgaaac tggatgtgta ttcgtaacct cataattttt atttgtgtat   1380
tgtttctttt attatttcag ttaaattttt acattatttt gcatgtatat ttctttgtac   1440
agagacctta catgtttaca cagtatgatg tgatgtaaat attttatttt gccatcagtt   1500
attttaaaaa attaaacata tttgcctgaa aaaaaaaaaa aaaggggggc gcnc         1554

<210> 1192
<211> 1268
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (27)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1224)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1225)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1226)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1227)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1230)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1257)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1265)
<223> n equals a,t,g, or c

<400> 1192
acaancccat agggaanttt ggnacgnctg nccgtaccgg tccggaattc ccgggtcgac     60
ccacggcggc ggcggccgga cccagactgg tagtgaggck ttggaccccg agccgctgca    120
atgccgctgg agctggagct gtgtcccggg cgctgggtgg gcgggcaaca cccgtgcttc    180
atcattgccg agatcggcca gaaccaccag ggcgacctgg acgtagccaa gcgcatgatc    240
cgcatggcca aggagtgtgg ggctgattgt gcyaagttcc agaagagtga gctagaattc    300
aagtttaatc ggaaagcctt ggagaggcca tacacctcga agcattcctg ggggaagacg    360
tacggggagc acaaacgaca tctggagttc agccatgacc agtacaggga gctgcagagg    420
tacgccgagg aggttgggat cttcttcact gcctctggca tggatgagat ggcagttgaa    480
ttcctgcatg aactgaatgt tccatttttc aaagttggat ctggagacac taataatttt    540
ccttatctgg aaaagacagc caaaaaaggt cgcccaatgg tgatctccag tgggatgcag    600
tcaatggaca ccatgaagca agtttatcag atcgtgaagc ccctcaaccc caacttctgc    660
ttcttgcagt gtaccagcgc atacccgctc cagcctgagg acgtcaacct gcgggtcatc    720
tcggaatatc agaagctctt tcctgacatt cccatagggt attctgggca tgaaacaggc    780
atagcgatat ctgtggccgc agtggctctg ggggccaagg tgttggaacg tcacataact    840
ttggacaaga cctggaaggg gagtgaccac tcggcctcgc tggagcctgg agaactggcc    900
gagctggtgc ggtcagtgcg tcttgtggag cgtgccctgg gctccccaac caagcagctg    960
ctgccctgtg agatggcctg caatgagaag ctgggcaagt ctgtggtggc caaagtgaaa   1020
attccggaag gcaccattct aacaatggac atgctcaccg tgaaggtggg tgagcccaaa   1080
ggctatcctc ctgaagacat ctttaatcta gtgggcaaga aggtcctggt cactgttgaa   1140
gaggatgaca ccatcatgga agaattggta gataatcatg gcaaaaaaat caagtcttaa   1200
aaataaagtg ccattctctg aatnnnnagn taaaaaaaaa aaaaaaaaaa aaagggnggc   1260
cgctntta                                                            1268

<210> 1193
<211> 809
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (778)
<223> n equals a,t,g, or c

<400> 1193
ggcaaggcga ggccccgggg gcgggccggg gtcaccacgc ctgccccagg gaaccgcaca     60
ggcacctgcg ctaagctgcg gctacccccg caagcaacct tccaagtcct tcgtggcaat    120
ggtgcttccg tggggaccgt gctcatgttc cgctgcccct ccaaccacca gatggtgggg    180
tctgggctcc tcacctgcac ctggaagggg agcatcgctg agtggtcttc agggtcccca    240
gtgtgcaaac tggtgccacc acacgagacc tttggcttca aggtggccgt gatcgcctcc    300
attgtgagct gtgccatcat cctgctcatg tccatggcct tcctcacctg ctgcctcctc    360
aagtgcgtga agaagagcra gcggcggcgc tccaacaggt cagcccagct gtggtcccag    420
ctgaaagatg aggacttgga gacggtgcag gccgcatacc ttggcctcaa gcacttcaac    480
aaacccgtga gcgggcccag ccaggcgcac gacaaccaca gcttcaccac agaccatggt    540
gagagcacca gcaagctggc cagtktgacc cgcagcgtgg acaaggaccc tgggatcccc    600
agagctctaa gcctcaktgg ctcctccagc tcaccccaag cccaggtgat ggtgcacatg    660
gcaaacccca gacagcccyt gcttgcttct gggytggcca cagggaatgc cacaacagcc    720
cgcagcwtwt gcctagggtg accasgatag ggytggtgcc atgytcacat tgggaggnca    780
gtttgacccc accagtcatt cagttacaa                                      809

<210> 1194
<211> 730
<212> DNA
<213> Homo sapiens

<400> 1194
gtgggaccat cttcctgtgg atcttctggc ctagcttcaa tgctgcactc acagcgctgg     60
gggctgggca gcatcggacg gccctcaaca catactactc cctggctgcc agcacccttg    120
gcacctttgc cttgtcagcc cttgtagggg aagatgggag gcttgacatg gtccacatcc    180
aaaatgcagc gctggctgga ggggttgtgg tggggacctc aagtgaaatg atgctgacac    240
cctttggggc tctggcagct ggcttcttgg ctgggactgt ctccacgctg gggtacaagt    300
tcttcacgcc catccttgaa tcaaaattca aagtccaaga cacatgtgga gtccacaacc    360
tccatgggat gccgggggtc ctgggggccc tcctgggggt ccttgtggct ggacttgcca    420
cccatgaagc ttacggagat ggcctggaga gtgtgtttcc actcatagcc gagggccagc    480
gcatgccacg tcacaggcca tgcaccagct cttcgggctg tttgtcacac tgatgtttgc    540
ctctgtgggc gggggccttg gaggcatcat attggtctta tgacctccta gacccctgtg    600
ccctgtggca tgggtggcam cctcctccat ggtggggggc agagaagcct cacagatcct    660
cccctaccac caccagggct cctgctgaag ctaccctttc tggactcccc ccccagactc    720
ccagcactac                                                           730

<210> 1195
<211> 894
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (830)
<223> n equals a,t,g, or c

<400> 1195
cgcaggagga aacagtaccg gctggaggcc ggtcttgcag gagcggggga ctgctggggg     60
cggggcttgg tggtgaccgc tggcggggcg gggcctgggg ctcagagggg tgggctttgg    120
agatcagagg gtcgacgctg cttcgttgcc tggactctgg tttccgccct ggagcaagcc    180
ggggcctggt cggcagctgg gccgccatgg agtccacgct gggcgcgggc atcgtgatag    240
ccgaggcgct acagaaccag ctagcctggc tggagaacgt gtggctctgg atcacctttc    300
tgggcgatcc caagatcctc tttctgttct acttccccgc ggcctactac gcctcccgcc    360
gtgtgggcat cgcggtgctc tggatcagcc tcatcaccga gtggctcaac ctcatcttca    420
agtggtttct ttttggagac aggccctttt ggtgggtcca tgagtctggt tactacagcc    480
aggctccagc ccaggttcac cagttcccct cttcttgtga gactggtcca ggcagccctt    540
ctggacactg catgatcaca ggagcagccc tctggcccat aatgacrgcc ctgtcttcgc    600
aggtggccac tcgggcccgc agccgctggg taagggtgat gcctagcctg gcttattgca    660
ccttcctttt ggcggttggc ttgtcgcgaa tcttcatctt agcacawttc cctcamcagg    720
tgctggctgg sctaataact ggcgctgtcc tgggctggct gatgactccc cgagtgccta    780
tggagcggga ctaagcttct atgggttgac tgcactggcc ctcatgctan gcaccagcct    840
catctattgg acctctttac actgggcctg gatctttctt ggtccatcag ccta          894

<210> 1196
<211> 1949
<212> DNA
<213> Homo sapiens

<400> 1196
ctcgagtttt tttttttttt tttttttaaa tggtagtcag atttcacgtg tatttttgct     60
aaaactgaaa gctgtcagga tccacattgg tgttaccagt ttgtactgaa gcctgataca    120
atacccaaca gtattgctct ggttttttca agcacacact ccaagcaagt ggtcagtctg    180
gcttaattca ttatggcttt ttttcagggt aagagattca cacgcaagag aataaggcta    240
caaatgctcc aaacatgggt ccagaactct ggctcttttg tgaggcctag agtcacagaa    300
aatgccatct gttaagaagc tgcttttgca taaaaaaata taaaaagtta caaaattcca    360
tcaaagacag atacacagta taaatcgtta ggtgaacaca gaaggctggt ctcatctcct    420
gcagtggccc atagacctgc cctgaggtct ggaagttcac tgtcctgagg gtccaggaac    480
tcctgcctgc tggctgggct ctaggaagaa ggagggtttg gctgggcccg cccagctccc    540
catgacactg tcactgtgat gccactgttg taccctctgt cttctggacc agtcagtcta    600
tgagctcttc tttgaaacag tcttagaccc agaatggtca tctcaccccc agaagacatg    660
gtttccaagg gtgggaggtg ttagttatgg gtgccgagcc ccacttcctg ggcgacaagg    720
caaaggtcaa tttctccctg cttcaagaat gaagagggaa ctggtgctcc ttgaaccaaa    780
gattcttgga agggtcattg tcaccaaagt ggctggtgtg ggcaggagca ccaagtgcag    840
acaaacccac cggggcctgg cggggcagcc ctgtcatggt ttctgtcttt gttcctgtta    900
gtgaaacaga agacccccga cccccgccac ctagcagcat ggaacacctg ctgcccagat    960
acagacaagg ctctgctttg tctccttgtg ctggtttttg gcagagacgt taaagggctg   1020
aaggcctgtg ggacagaaat ggggagaagg agtgggatac ccaagatgcc ctcatacgca   1080
gcgtggtcaa cagtgctgag ctgaggggca agcctggtag gctgggctca ggcagaacct   1140
gaggctgtag ggggcctgct gtgtccgcag ccccctctgc aactcagaag tccaggcctc   1200
cgctccaacg ccagcgaccc ctgtgaggcg caggggtgga ggcctgtgtg gctcaggttg   1260
ccaaggcacc cgccaggcct tcagtcagag tccgagtcgg aattctcttc ttctgtcttg   1320
tgggctgtgg tctcatctgc agagtcccct tgtttgagga atttggccac gtcgttaaag   1380
atcaggtaga aatcagttgc aaacacgatg gtagcaaaga agccaaacac cccagcggct   1440
ttggaagccc catccgagta cttggcgatg gccgtgatgg agatagcaaa gtagatgagg   1500
gccgcggtga cacagcgcag gaagtccatc atgggccagc acaagccctg ccacttgtca   1560
ttcagctgca tggcatcagc aaagaggaag tacaaggcca gcaggaactc cagcagaggc   1620
gctgtgagga aggcagatgc tgaggacgcc acatagcaga taaaagtgat gaatgagaga   1680
cccgactcgg ccagcaggag gcggcctttg agagagcaga ggaaagcccg cgccggcagc   1740
agggcgcgga gcccggggac cgcggggccg ggacgggagc cgccggcagg ctcggggtcc   1800
gggtcggggt cggggtctgg gggccacatg gcggcggcgg cggtagggcc ggggctcggc   1860
ctggctcccc tcttctcgcg cccggaggga agcggaaacc cgggctgtgc ggaaksaggg   1920
cargcgacac tggctcgcgc agggtcgca                                     1949

<210> 1197
<211> 396
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (314)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (342)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (368)
<223> n equals a,t,g, or c

<400> 1197
tcgacccacg cgtccggagc tccacaacat ctacggtttt tatcatcaaa tggctactgc     60
agaaggactg ataaaacgat ctaaagggaa ggagagaccc tttgttctta cacgttcttt    120
ctttgctgga tcacaaaagt atggtgccgt gtggacaggc gacaacacag cagaatggag    180
caacttgaaa atttctatcc caatgttact cactctcagc attactggga tctctttttg    240
cggactgtac ataggcgggt tcattgggga atccagagac agagctgcta gtgcgttggt    300
accaggctgg agcntaccag cccttcttcc gtggccatgc cncatggaac accaagcgac    360
gagagccngg ctctttgggg aggaacacac ccgaat                              396

<210> 1198
<211> 1674
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (412)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (421)
<223> n equals a,t,g, or c

<400> 1198
tgcccctgat ggcctcctgg agagcattgc gntggccaaa gccttcgcat ctcagaataa     60
ttaccgcatc gatgccaacc aggagctgct ggccatcggt ctcaccaaca tgttgggctc    120
cctcgtctcc tcctacccgg tcacaggcag ctttggacgg acagccgtga acgctcagtc    180
gggggtgtgc accccggcgg gggccctggt gacgggagtg ctggtgctgc tgtctctgga    240
ctacctgacc tcactgttct actacatccc caagtctgcc ctggctgccg tcatcatcat    300
ggccgtggcc ccgctgttcg acaccaagat cttcaggacg ctctggcgtg ttaagaggct    360
ggacctgctg cccctgtgcg tgaccttcct gctgtgcttc tgggaggtgc antacggcat    420
nctggccggg ggcctggtgt ctctgctcat gctcctgcac tctgcagcca ggcctkagac    480
caaggtgtca gaggggccgg ttctggtcct gcagccggcc agcggcctgt ccttccctgc    540
catggaggct ctgcgggagg agatcctaag ccgggccctg gaagtgtccc cgccacgctg    600
cctggtcctg gagtgcaccc atgtctgcag catcgactac actgtggtgc tgggactcgg    660
cgagctcctc caggacttcc agaagcaggg cgtcgccctg gcctttgtgg gcctgcaggt    720
ccccgttctc cgtgtcctgc tgtccgctga cctgaagggg ttccagtact tctctaccct    780
ggaagaagca gagaagcacc tgaggcagga gccagggacc cagccctaca acatcagaga    840
agactccatt ctggaccaaa aggttgccct gctcaaggca taatggggcc acccgtgggc    900
atccacagtt tgcagggtgt tccggaaggt tcttgtcact gtgattggat gctggatgcc    960
gcctgataga catgctggcc tggctgagaa acccctgagc aggtaaccca gggaagagaa   1020
ggaagccagg cctggaggtc cacggcaggg gagtggggct cactggcttc ctgtgggatg   1080
actggaaaat racctcgctg ctgttccctg gcatgaccct ctttggaaga gtggtttgga   1140
gagagccttc tagaatgaca gactgtgcga ggaagcaggg gcaggggttt ccagcccggg   1200
ctgtgcgagg catcctgggg ctggcagcac cttcccggct caccagtgcc acctgcgggg   1260
gagggacggg gcaggcagga gtctgggagg cgggtccgct cctcttgtct gcggcatctg   1320
tgctctccga gagaaaacca aggtgtgtca aatgacgtca agtctctatt taaaaataat   1380
tttgtgtttt ctaaatggaa aaagtgatag ctttggtgat tttgtaaaag tcataaatgc   1440
ttattgtaaa aaatacagga aaccacccct caccctgtcc acttgggtga tcattccaga   1500
cccctcccca aacatgcata tgtacctgtc cgtcagtgtg tggatgtatg tttacagttc   1560
tacataaatg ggatcatttt atacatggtg ctctggaacc cacatttttc atgcagtcat   1620
ttgcagtgaa ttatttattg tgataataaa tagcattaga atacaaaaaa aaaa         1674

<210> 1199
<211> 555
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (334)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (379)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (462)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (482)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (487)
<223> n equals a,t,g, or c

<400> 1199
ggcacgagtg aaaatgaagg aatgccttcg aatcaaggaa agatagacaa tgaagaacag     60
ccaccgcacg agggaaagcc agaagtagct tgtattctgg aagacaagaa gttagaaaac    120
gagggaaaca cagaaaacac gggcaagaga gttgaggaac cgttaaagga taaagaaaag    180
ccagagagtg cgggaaaggc aaaaggagaa ggaaagtcag agaggaaggg aaagtcagag    240
atgcagggag gatcaaagac agagggaaag ccagagagag ggggaagggc agagggtgaa    300
ggagagccag acaktgaaag agagccagag aktnagggag agccagaaak tgaaacaagg    360
gyttcaggaa agcgcccant tgaggttgtt ttaccccgga aagcccaaaa gaaaaaccaa    420
caggggtttg ttcattacct cagcattttt aggagcctta cngttttgat tttcagcatt    480
tngggcntgt taggggtttt tgcacttgtt aggttggggt taaaggagaa agcaacagat    540
tttgggcttt ttttg                                                     555

<210> 1200
<211> 2123
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2003)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2012)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2023)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2065)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2089)
<223> n equals a,t,g, or c

<400> 1200
ggagctgccc cggcgccccg cgcccccggc agccgtgctc ggctgctacc tcttcaactg     60
cacggcgcgc ggccgcaacg tctgcaagtt cgcgctgcac agcggctaca gcagctacag    120
cctcagccgc gcgccggacg gcgccgccct ggccaccgcg cgcgcctcgc cccggcagga    180
aaaggatgcg cctccactta gcaaggctgg gcaggatgtg gttctgcatc tgcccacaga    240
cggggtggtt ctagacggcc gcgagagcac agatgaccac gccatcgtcc agtatgagtg    300
ggcactgctg cagggggacc cgtcagtgga catgaaggtg cctcaatcag gaaccctgaa    360
gctgtcccac ctacaggagg gaacctacac cttccagctg accgtgacgg acactgccgg    420
gcagagaagc tctgacaacg tgtcagtgac agtgcttcgc gcagcctact ccacaggagg    480
atgtttgcac acttgctcac gctaccactt cttctgtgac gatggctgct gcattgacat    540
cacgctcgcc tgcgatggag tgcagcagtg tcctgatggg tctgatgaag acttctgcca    600
gaatctgggc ctggaccgca agatggtaac ccacacggca gctagtcctg ccctgccaag    660
aaccacaggg ccgagtgaag atgcaggggg tgactccttg gtggaaaagt ctcagaaagc    720
cactgcccca aacaagccac ctgcattatc aaacacagag aagaggaatc attccgcctt    780
ttggggacca gagagtcaaa tcattcctgt gatgccagat agtagttcct cagggaagaa    840
cagaaaagag gaaagttata tatttgagtc aaagggtgat ggaggaggag gggaacaccc    900
agccccagaa acaggtgcag tgctacccct ggcgctgggt ttggctatca ctgctctgct    960
gcttctcatg gttgcatgcc gactacgact ggtgaaacag aaactgaaaa aagctcgtcc   1020
cattacatct gaggaatcgg actacctcat aaatgggatg tatctatagt aatgtaattt   1080
caataccttg gggcagggac atgttttgtt tataatttat acatctatta agttctggat   1140
atttacagct tcttttgttt ttaattgggc cagaagattc tgcaaatccc aaatctttct   1200
ttattattta ttgtaaaaaa agkttcctta gaagtcataa aatattttga aatttagaga   1260
ggaattcatg attaaagatt cctaaaaata taattctgat ttatgtaagc tgtccctgaa   1320
aatagaaatg tgtacttagc tgagagaaaa ttcagcatct caggaggtgg tattaggatg   1380
actgtgttaa cccattacct tttagaagcc aactgttggc cccttaccat gctggactgc   1440
tataggccca gcttcccctt gttctgtggc ccttttcttc ctccttgaag ctcccagtat   1500
tctttttctt ttcccctcta aacctgtttc tgagagtgga tctcaagcaa gttcatgcct   1560
tcaatcagat gttacttagg gtgggtatac ctaaattata aaccttatgt acaagtcagt   1620
aagccttagg gaaggtgagt gtgggtcctt cctaatccct ctgacgtcat gtcatatagg   1680
tggctgcctc cttagactga cctttgggag aaaaaaaccc cagactttga attagtaaca   1740
gctctaagat ggtcatgcag tgagatagga aatcaagatg gaagcagaga atctggcatg   1800
ccaaaaacta acagaaactt agttgaaggc aaagagagca aggagaacgt ttaatacttc   1860
attacatcaa atcaacactg ctccatggtg agagcacagc aactcattta tatatatata   1920
tatagggctt tgttgatgaa aaacgacaat ttgaaggaga ggacgttgag tgggttcctg   1980
ggggtacagc tttttgttaa aantgttcac cntgggcttt tcntcccatg ggattgagtc   2040
cgatgttttt ttaatgctat taaantgttt aggattgtgg ccctccgcnt attgcccggg   2100
tttacgtttt ttcttggacc ctt                                           2123

<210> 1201
<211> 1997
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> n equals a,t,g, or c

<400> 1201
cggacgcgtg ggggagcaga cccttgacaa gaagctgatg tcagatctga ggaggaaacg     60
tactgcacat gagcgtgcca aggaacttta cagttcgggg gagttttcca gtggcagaaa    120
gtggggagat gatgctccca aggaagaagt anataccggg gctgtgaact tgattgagtc    180
aggagcttgt ggagcttttg ttcatgggtt ggaagatgag atgtatgagg ttcgtattgc    240
tgctgtggag gccctctgca tgttggccca gtcttcaccc tcttttgctg agaagtgcct    300
tgatttccta gttgacatgt tcaacgatga aattgaggaa gtacgtctgc agtctataca    360
taccatgaga aaaatctcta acaacatcac cctccgagaa gatcagcttg acactgtcct    420
ggctgtgcta gaggattcat ccagagatat tcgagaggct cttcatgaac tcttatgctg    480
tactaatgtt tcaaccaaag aagggattca tcttgcattg gtggagctgc tgaaaaattt    540
aaccaagtac cctactgata gggactccat atggaagtgc ttgaagtttc tgggaagtcg    600
gcatccaacc ctggtgcttc ccttggtgcc agagcttctg agcacccacc cattttttga    660
cacagctgaa ccagacatgg atgatccagc ttatattgca gttttggtac ttattttcaa    720
tgctgctaaa acctgtccaa caatgccagc attgttctca gatcacacct tcaggcacta    780
tgcctacctc cgagacagtc tttctcatct tgttcctgcc ttgaggttac caggtagaaa    840
actggtgtca tcagctgttt ctcccagcat catacctcaa gaggatcctt cccagcagtt    900
cctgcagcag agccttgaaa gagtgtatag tcttcagcac ttggaccctc agggagccca    960
ggagctgctg gaattcacca tcagggatct gcaaagactt ggagaacttc aatctgaatt   1020
ggcaggagta gctgatttct ctgccaccta tcttcgctgt caactacttc tcatcaaggc   1080
cttgcaggaa aagttgtgga atgtagctgc ccctttgtat ttgaagcaga gtgatttggc   1140
ctcagcagca gcgaaacaga ttatggaaga gacctacaaa atggaattca tgtacagtgg   1200
tgtggagaat aagcaggtgg tgattataca tcacatgagg ctgcaggcca aagctttgca   1260
acttatagta acagcacgaa ctacacgagg acttgacccc ttatttggga tgtgtgaaaa   1320
atttttacag gaagtagact tttttcagag gtatttcatc gctgatttgc cccacttgca   1380
ggacagcttt gtggacaaac tccttgacct tatgccccga ctcatgacat ccaaacctgc   1440
agaagtggtc aaaattctac agaccatgct gcgacagagt gcctttctgc atctcccgct   1500
tccagagcag atccacaaag cctcagccac catcatcgag ccagcgggcg agtcagacaa   1560
ccctttgcgg tttacctctg ggttggtggt tgccctggat gttgatgcaa ctccagtgct   1620
cgcattccaa aatgcccctg gatggagggt ggtgagatgt caccacaggt ggaaaccagc   1680
atcgagggca ccattccctt cagcaagcct gtaaaagttt atataatgcc caaacctgca   1740
cggcgctaag gcaaaaacag tcttcccaac cgtggcctag agggcccttc ttaggtgtca   1800
gaatgagcca agcctgaagc acttcacctg gaattgatgt gtaggcttaa ggagtatgtg   1860
acccttacag tctcatctgg tatcaaacac aggataaatt gtttcttcat taaaaaataa   1920
aaaaccttca agtctactta cccttctcct gtccacaata aagttgagaa aacaaaaaaa   1980
aaaaaaaaaa aaaaatt                                                  1997

<210> 1202
<211> 1257
<212> DNA
<213> Homo sapiens

<400> 1202
cttttaggtg acactataga aggacgcctg caggtaccgg tccggaattc ccgggtcgac     60
ccacgcgtcc ggcgagctgg ggccgcgcaa tgtcgcacgg agccgggctc gtccgcacca    120
cgtgcagcag cggcagcgcg ctcggacccg gggccggcgc ggcmcagccc agcgcgagcc    180
ccttggaggg gctgctggac ctcagctacc cccgcaccca cgcggccctg ctgaaagtgg    240
cgcaaatggt caccctgctg attgccttca tctgtgtgcg gagctccctg tggaccaact    300
acagcgccta cagctacttt gaagtggtca ccatttgcga cttgataatg atcctcgcct    360
tttacctggt ccacctcttc cgcttctacc gcgtgctcac ctgtatcagc tggcccctgt    420
cggaacttct gcactattta atcggtaccc tgctcctcct catcgcctcc attgtggcag    480
cttccaagag ttacaaccag agcggactgg tagccggagc gatctttggt ttcatggcca    540
ccttcctctg catggcaagc atatggctgt cctataagat ctcgtgtgta acccagtcca    600
cagatgcagc cgtctgatga ggccacaacc cctaggcccc tcaggagctt tgcagagagg    660
aggacgtgta ctccaggcga ggcctctgga cctgtgttcc tgtgccaaag tcctgtcagg    720
ctggtgggca ccaggaaagg cctgcaccct cttcctgctc tcccaggaag ccagctccct    780
gagctcctga gccagccgga aactcttcct ccagccttcc ggggagaaca tccctcccat    840
tctgggaaag gaaagcagcc tccagggaaa tgttttctgc cttcctgctt ctagaaccac    900
ctcaggtact gatgaacccc acttagcaca gctgaagggg tttgtgaata ctcccgccta    960
aatcccttct acttcactcc tcaggggagt gaagtgcctt aagaaacaaa gccctgtcct   1020
aatttatcta gcttgtcagt ccggtcttag agataccctc tttcctgaag tgaggcgtgc   1080
ctgtagaaac actatgtggt cagcctgtcc ccaaggagat cttgtgtctc ctctccatct   1140
ctgcctttgt taccagtgtg catgtgtttg tgtgtttttt aataaaatat tgactcggcc   1200
agttaaaaaa aaaaaaaaaa aaaaaaaggg ggccgtttta aaggatccaa gtttacg      1257

<210> 1203
<211> 1503
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (829)
<223> n equals a,t,g, or c

<400> 1203
tatggctgag ascttcaagg agctggaccc tgattccagc atggggaagg ccttggagat     60
gagctgtgcc atccagaatc agctggcccg catcctggcc gagtttgaga tgaccctgga    120
gagggacgtc ctgcagccac tcagcaggct gagtgaggag gagctgccag ccatcctcaa    180
acacaagaaa agcctccaga agctcgtgtc cgactggaac acactcaaga gcaggctcag    240
tcaggcaacc aagaattcag gcagcagtca aggcctagga ggcagcccgg gtagtcacag    300
ccatacgacc atggccaaca aggtggagac gctgaaggag gaggaggagg agctgaagag    360
gaaagtggag caatgcaggg acgagtactt ggctgacctg taccactttg ttaccaagga    420
ggactcctat gccaactact tcattcgtct cctggagatt caggccgatt accatcgcag    480
gtcactgagc tcgctggaca cagccctggc tgagctgagg gagaaccacg gccaagcaga    540
ccactcccct tcgatgacag ccacccactt ccccaggtgt atggggtgtc gctggcaacc    600
cacctgcaag agctgggccg ggagattgcc ctgcccatcg aggcctgcgt catgatgctg    660
ctttctgarg gcatgaagga agarggtctc ttccgtctgg ctgctggggc ctcggtgctg    720
aagcgtytma agcagacaat ggcctcggac ccccamagcc tggaggagtt ctgctccgam    780
ccgsamgctg tggcaggtgc cctcaagtcc tatctgcggg agctgccana gcctctgatg    840
accttcgacc tctatgatga ctggatgagg gcagccagcc tgaaggagcc aggggcccgg    900
ctgcaggccc tccaagaggt gtgcagccgc ctaccccccg agaacctcag caacctcagg    960
tacctgatga agttcctggc acggctggcc gaggagcagg aggtgaacaa gatgacaccc   1020
agcaacatcg ccatagtcct gggacccaac ttgctgtggc cacctgagaa agaaggggac   1080
caggcccagc tggatgcagc ctccgtgtct tccatccagg tggtgggcgt cgtcgaggcg   1140
ctgatccaga gcgcagacac cctcttccct ggagacatca acttcaacgt gtcaggcctc   1200
ttctcagctg ttaccctcca ggacacagtc agtgacaggc tggcctctga ggaacttccg   1260
tccactgccg tgcccacccc agccaccamc ccggctccgg ctccggctcc agctccagct   1320
mcggscccag ccttggcttc agcagctacc aaggaaaggm cagagtctga ggtgcctccc   1380
agaccagcct yccccaaggt caccaggagt cccccggaga cagctgcccc agtggaggac   1440
atggctcgga ggaccaagcg cccggcgcca gccggcccac catgccgccc cccaggtytc   1500
cgg                                                                 1503

<210> 1204
<211> 1706
<212> DNA
<213> Homo sapiens

<400> 1204
gggctgtccc ccgccctgcc cggcccgagc cccgcgggcc gccgccgcca ccgccgccat     60
gaagaagcag ttcaaccgca tgaagcagct ggctaaccag accgtgggca ggaaaattaa    120
agaaataatg ctgagaggaa ggtagacgtg tggtaatggc ggctgatgtt tcaaggaaca    180
gtttacaagc acatgataat ttcttagctg agaaaacaga agtccttagt gaagatctat    240
tacagattga gagacgcctg gacacggtgc ggtcaatatg ccaccattcc cataagcgct    300
tggtggcatg tttccagggc cagcatggca ccgatgccga gaggagacac aaaaaactgc    360
ctctgacagc tcttgctcaa aatatgcaag aagcatcgac tcagctggaa gactctctcc    420
tgggatgctg gagacgtgtg gagatgctga gaatcagctg gctctcgagc tctcccagca    480
cgaagtcttt gttgagaagg agatcgtgga ccctctgtac ggcatagctg aggtggagat    540
tcccaacatc cagaagcaga ggaagcagct tgcaagattg gtgttagact gggattcagt    600
cagagccagg tgggaaccaa gctyacaaat cctcaggawc caactttcag gggcttccat    660
caaaaataga tactctaaag gaagagatgg atgaagctgg aaataaagta gaacagtgca    720
aggwtcaact tgcagcagac atgtacaact ttatggccaa agaaggggag tatggcaaat    780
tctttgttac gttattagaa gcccaagcag attaccatag aaaagcatta gcagtcttag    840
aaaagaccct ccccgaaatg cgagcccatc aagataagtg ggcggaaaaa ccagcctttg    900
ggactcccct agaagaacac ctgaagagga gcgggcgcga gattgcgctg cccattgaag    960
cctgtgtcat gctgcttctg gagacaggca tgaaggagga gggccttttc cgaattgggg   1020
ctggggcctc caagttaaag aagctgaaag ctgctttgga ctgttctact tctcacctgg   1080
atgagttcta ttcagacccc catgctgtag caggtgcttt aaaatcctat ttacgggaat   1140
tgcctgaacc tttgatgact tttaatctgt atgaagaatg gacacaagtt gcaagtgtgc   1200
aggatcaaga caaaaaactt caagacttgt ggagaacatg tcagaagttg ccaccacaaa   1260
atwttgttaa ctttaggtat gtatgattga gctacaatga ctctggagtg aagataagtt   1320
taatgcccag cagagaagtc atttaattca ggcatacttg gcacattaaa aaacaacaac   1380
aacaacaaaa aaaaccacat cactttggag agtaacttgg ggctactggg aatgggattt   1440
catgtatatt atgatgaatt tgaagcatca gtatcatgcc tgacattaat acgtaagttg   1500
gcttatcatt ttcccactac agctattagc aataaatttc ttgtgaaaag tttgagtgac   1560
tgtatgttgg gtttggagtc caaatcatcc agtatgttaa aaggcaaaat taatcaataa   1620
ttgtacattc tgtaatgtct tttatatatg ctacttaatt taaagtataa atcatcttac   1680
taaataaaat ttcaaagaat ggagat                                        1706

<210> 1205
<211> 2537
<212> DNA
<213> Homo sapiens

<400> 1205
atgtattggg tattgagctg aaacaacaaa aagctgtgaa aatcaaaaca aaagattctg     60
gtcttttttg cgttccattg acagcgctat tagaacaaga tcagaggaaa gtaccaggaa    120
tgcgaatacc cttgatcttt caaaaactga tttctcgaat tgaagagaga ggtttggaaa    180
cagaaggcct cttacggatc cctggagctg ccattagaat caagaatctt tgccaagaac    240
tagaagcaaa gttttatgaa gggactttta attgggaaag tgtcaaacag catgatgccg    300
ccagcctgct gaagctcttc attcgggagt tgccccagcc actgctcagt gtggagtatc    360
tcaaagcstt tcaggctgtc cagaatcttc caaccaagaa gcagcaacta caggctttga    420
accttcttgt catcctccta cctgatgcaa acagggacac actgaaggcc cttcttgaat    480
ttctccaaag agtaatagat aataaagaaa aaaataaaat gacagtcatg aatgtagcaa    540
tggtcatggc cccgaatctc tttatgtgtc atgcattggg attgaagtcc agtgaacagc    600
gagaatttgt aatggcagct gggacagcaa ataccatgca cttattgatt aagtaccaaa    660
aacttctgtg gacaattccc aagtttattg taaaccaagt gaggaagcaa aacacggaaa    720
atcataaaaa ggataaaaga gccatgaaga aattgctgaa gaaaatggct tatgaccgag    780
aaaaatatga aaagcaagat aagagtacaa atgatgctga cgttcctcag ggagtgattc    840
gagtgcaagc tccccatctt tcgaaagttt ccatggcaat acagctaact gaagaactaa    900
aagccagtga tgtacttgcc aggtttctca gccaagaaag tggggttgcc cagactctca    960
agaaaggaga agtttttttg tatgaaattg gaggaaatat tggggaacgc tgccttgatg   1020
atgacactta catgaaggat ttatatcagc ttaacccaaa tgctgagtgg gttataaagt   1080
caaagccatt gtagaagact taacaagctg cagataacca tgtggacttc tgtcataatt   1140
cttgctgagt caagagtgta aataaaagaa atggcaggac tcatattatt cagttgtacc   1200
caagtattta aaaatgactc tcttaagcct taaaaagtca tagatttgtg ctgctgccag   1260
aattatatta attattatta atgttattat tagaaaaaaa atttctggag tgagagtaaa   1320
gaggcttaat tagtttgtgg gcagttttca tatgctctgt gaaatgtgtc cagatgtgac   1380
atagtttttt ttttttaata tgtggaaatg tcttctcttc ccattctttt ctcctaaaat   1440
catatatact gtaatatatg ctctctcacc tctattacct cctcacatct accctttccc   1500
agttaggttt gctttttgac caaaaagata acaaatacca ggtatggcaa gttgtgaaga   1560
cagcacatta aaacatacct aatttcacag tattcctgtc acgacagaat gttagtattc   1620
atctctttga atcatttgct caaataataa cattccacct tttcctgctg tatcacagga   1680
agtgatttgc attttttttc agttcatctg acttatgttc acagaaccgt atcagcgacc   1740
aagaaaatag gactgtcaga agctgccagt tattactgaa ccattaaata cttatatact   1800
aagaataaat aaaatatacc catgtgaaat aataattgga ttatggataa caagagagtg   1860
aaagccaaag cactttctgt ctactgtact cttctaaatg gaattttaaa agtcatagct   1920
ggctttacgt gttgtcatta ttagcattat aaatatgcat gatagtataa tccagtaatg   1980
gttgaagaat gtattttact taaagaggga tttttttttt taagtcctga ataagtctac   2040
tggaagaatt attcttctgg gtgaaaaagc ttttgtttgt gttcttattt taaataatcg   2100
gagtcaattt attaaaatgt tcttgaaagt actattccca gggattttaa tgcacaaacc   2160
atattgtgac aagagatgag cctctgtact gtaaataaga aatgaagtag agaaatgtta   2220
aatattttat gagtttagaa tatagtaaat aaaaggtgat gtaaatgaat gctgcacaaa   2280
cggtgttcat gatactttta gtagtacttt aggaaaaact acacattctc agaagctctt   2340
gatgtctcta atgaaggggg ggaatgctgt taatgagaac agtcataaat ttttagcata   2400
taattacaag aacagcctgt ggatatgatc acttaaatga ttttgtggtg attcgtgcca   2460
ttgctttttt atttaaaaga aaattttgta attaaatgcc tttttctaaa ttaaaaaawa   2520
aaaaaaaaaa actcgac                                                  2537

<210> 1206
<211> 945
<212> DNA
<213> Homo sapiens

<400> 1206
gggaaattgg aagacttggt ggcgaacgag ggtcaggacc tgcatcctgc ctcagagagt     60
tatcgacgta tccggaatgt gggatcagag gctggtgagg ttggccctgt tgcagcatct    120
gcgggccttc tatggtatta aggtgaaggg tgtccgtggg cagtgcgatc gcaggagaca    180
tgaaacagca gccacggaaa tagggggtaa aatatttgga gtacctttta atgcactgcc    240
ccattctgct gtaccagaat atggacacat tccaagcttt cttgtcgatg cttgcacatc    300
tttagaagac catattcata ccgaagggct ttttcggaaa tcaggatctg tgattcgcct    360
aaaagcacta aagaataaag tggatcatgg tgaaggttgc ctatcttctg cacctccttg    420
tgatattgcg ggacttctta agcagttttt tagggaactg ccagagccca ttctcccagc    480
tgatttgcat gaagcacttt tgaaagctca acagttaggc acagaggaaa agaataaagc    540
tatactgttg ctctcctgtc ttctggctga ccacacagtt catgtattaa gatacttctt    600
taactttctc aggaatgttt ctcttagatc cagtgagaat aagatggata gcagcaatct    660
tgcagtaata tttgcaccaa atcttcttca gacaagtgaa ggacatgaaa agatgtcttc    720
taacgcagaa aagaaggtac gattacaggc tgcagtagta cagactctta tcgattatgc    780
atcagatatt ggtaagatgt agttgcatta ttaacagaat ttgtttaaat gaggaaaatc    840
tctgtttctt tcaaaggaac tatgaaggca actgttagaa agttggtata ttactgacct    900
cacccccacc ctacagtacc ggcccctcct gcaaagaaaa aaaaa                    945

<210> 1207
<211> 724
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (646)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (709)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (720)
<223> n equals a,t,g, or c

<400> 1207
ggcagagtat tggttggggg aaacccacga ggggacgcgg cgaggagggt cgctgtccac     60
ccgggggcgt gggagtgagg taccagattc agcccatttg gccccgacgc ctctgttctc    120
ggaatccggg tgctgcggat tgaggtcccg gttcctaacg aatctctgct ggattggccg    180
taaccctgtc cccgagcggg ctcacagggt ctgaaggcca cgcatgaggc aaaggtaaag    240
ttctgagcca cccggtgcct ccttcccagg actgcaagat ggaggaaggc gggaacctag    300
gaggcctgat taagatggtc catctactgg tcttgtcagg tgcctggggc atgcaaatgt    360
gggtgacctt cgtctcaggt agggaccctc agcttggatg tcatgggtac ctggggtggg    420
gatggaaata agaggggaac cgggaagtgc cctaacaccc ctgtggtccc cataccctgc    480
aggcttcctg cttttccgaa gccttccccg acataccttc ggactagtgc agagcaaact    540
cttccccttc tacttccaca tctccatggg ctgtgcttca tcaacctctg catcttggct    600
tcacagcatg cttgggstca gctcacattc tgggaggcca gccagnttta cctgctgttc    660
ctgagcctta cgctggccac tgtcaagccg ctggtggaac ccggaccana gctgcatgtn    720
ggcc                                                                 724

<210> 1208
<211> 644
<212> DNA
<213> Homo sapiens

<400> 1208
ggccgaggag ggtcgctgtc cacccggggg cgtgggagtg aggtaccaga ttcagcccat     60
ttggccccga cgcctctgtt ctcggaatcc gggtgctgcg gattgaggtc ccggttccta    120
acggtgggat cggtgtcctc gggatgagat ttggcgtttc ctcggggctt tggtgggatc    180
ggtgtcctca ggatgagatt tagggtttcc tcggggcttt cgggatcttc acctaatatc    240
cggactgcaa gatggaggaa ggcgggaacc taggaggcct gattaagatg gtccatctac    300
tggtcttgtc aggtgcctgg ggcatgcaaa tgtgggtgac cttcgtctca ggcttcctgc    360
ttttccgaag ccttccccga cataccttcg gactagtgca gagcaaactc ttccccttct    420
acttccacat ctccatgggc tgtgccttca tcaacctctg catcttggct tcacagcatg    480
cttgggctca gctcacattc tgggaggcca gccagcttta cctgctgttc ctgagcctta    540
cgctggccac tktcaacgsc cgctggctgg aaccccgcam cacagctgcc atgtgggccc    600
tgcaaaccgt ggagaaggag cgaggcctgg gtggggaggt acca                     644

<210> 1209
<211> 843
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> n equals a,t,g, or c

<400> 1209
cccatcctga tccaagtgcc cttattcaag gtgttgctga tattttgncc ttcactgccc     60
actcatartg argcaaatta ycattttctg kgaacacagc tcagattttg gctggaatgg    120
ctatggctta tgcagtggca acttcttgtt gtagtcttwt tgcaaactct gattcttcag    180
caatatcaac gttttaacat gctcacctca gcaaaagtta agacagctgt aaatggactg    240
atctacaaaa aggccttact tttatcaaat gtttctcrac aaaagttttc cactggggaa    300
attattaact tgatgtcagc aactcatgga cttgacagca aacctcaatc tcctctggtc    360
tgcccctttt caaatcctaa tggccgtata tctcctttgg caagagctgg gtccagcagt    420
gttagcaggg gtggcagtcc ttgtgtttgt tataccaata aatgctttag ctgcaactaa    480
aataaaaaag ttaaaggtgt ccctggcaac cttgtgtgtc tatttcttac tggatgaagg    540
aaacatttta acagccacta aagtgttcac atcgatgtct ttgtttaata ttttaaggat    600
tcctctgttt gagttaccaa ccgtgatctc agctgtggtc cagacaaaga tatccctggg    660
ccgtttggaa gactttctca acactgagga gcttcttcct caaagtattg aaacgaacta    720
tacaggagat catgctattg ggtttacaga tgcttctttc tcctgggata aaacaggaat    780
gccagttcta aaagaggctc tgtggcttat gkttctcaac aagcctggat tcaaaattgc    840
cgg                                                                  843

<210> 1210
<211> 793
<212> DNA
<213> Homo sapiens

<400> 1210
gcccacgcgt ccggttctcc tgcttgccat caatggagtg acagagtgtt tcacatttgc     60
tgccatgagc aaagaggagg tcgacaggta caattttgtg atgctggccc tgtcctcctc    120
attcctggtg ttatcctatc tcttgacccg ttggtgtggc agcgtgggct tcatcttggc    180
caactgcttt aacatgggca ttcggatcac gcagagcctt tgcttcatcc accgctacta    240
ccgaaggagc ccccacaggc ccctggctgg cctgcaccta tcgccagtcc tgctcgggac    300
atttgccctc agtggtgggg ttactgctgt ttcggaggta ttcctctgct gtgagcaggg    360
ctggccagcc agactggcac acattgctgt gggggccttc tgtctgggag caactctcgg    420
gacagcattc ctcacagaga ccaagctgat ccatttcctc aggactcagt taggtgtgcc    480
cagacgcact gacaaaatga crtgacttca gggaagcctg gacacccgag gcacctggac    540
cagctatggg tagttctgtg ggtggaacac attctgtgta agagccccac tgagggctct    600
gcagcggagt gacagcaacc ccagagatga ggcaccagag agtgccactg catgagacac    660
ctgtgaccat tcgaagtctg aaatgcgggg ggggagtttc atttttaagt gaagaccaaa    720
agccctttaa aaataatagt tttttatcat tttatagtaa aaaaaaaaaa aaaaaaaaaa    780
aaagggcggc cgc                                                       793

<210> 1211
<211> 530
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (517)
<223> n equals a,t,g, or c

<400> 1211
gcctggcaga gagactctga aatgagggat tagaggtgtt caaggagcaa gagcttcagc     60
ctgaagacaa gggagcagtc cctgaagacg cttctactga gaggtctgcc atggcctctc    120
ttggcctcca acttgtgggc tacatcctag gccttctggg gcttttgggc acactggttg    180
ccatgctgct ccccagctgg aaaacaagtt cttatgtcgg tgccagcatt gtgacagcag    240
ttggcttctc caagggcctc tggatggaat gtgccacaca cagcacaggc atcacccagt    300
gtgacatcta tagcaccctt ctgggcctgc ccgctgacat ccaggctgcc caggccatga    360
tggtgacatc cagtgcaatc tcctccctgg cctgcattat ctctgtggtg ggcatgagat    420
gcacagtctt ctgccaggaa tcccgagcca aagacagagt ggcggtagca ggtggagtct    480
ttttcatcct tggaagcctc ctgggattca ttcctgntgc ctggaatctt               530

<210> 1212
<211> 1379
<212> DNA
<213> Homo sapiens

<400> 1212
ggctcgctcc tggggctcgg cgggctggac gccgagtgcg gccggcccct cttcgccacc     60
tactcgggcc tctggaggaa gtgctacttc ctgggcatcg accgggacat cgacaccctc    120
atcctgaaag gtattgcgca cgatgcacgg ccatcaagta ccacttttct cagcccatcc    180
gcttgcgaaa cattcctttt aatttaacca agaccataca gcaagatgag tggcacctgc    240
ttcatttaag aagaatcact gctggcttcc tcggcatggc cgtagccgtc cttctctgcg    300
gctgcattgt ggccacagtc agtttcttct gggaggagag cttgacccag cacgtggctg    360
gactcctgtt cctcatgaca gggatatttt gcaccatttc cctctgtact tatgccgcca    420
gtatctcgta tgatttgaac cggctcccaa agctaattta tagcctgcct gctgatgtgg    480
aacatggtta cagctggtcc atcttttgcg cctggtgcag tttaggcttt attgtggcag    540
ctggaggtct ctgcatcgct tatccgttta ttagccggac caagattgca cagctaaagt    600
ctggcagaga ctccacggta tgactgtcct cactgggcct gtccacagtg cgagcgacty    660
ctgaagggga acarcgcgga gttcaaggag tccaagcaca aagcggtctt ttacattcca    720
acctgttgcc tgccagccct ttctggatta ctgatagaaa atcatgcaaa acctcccaac    780
ctttctaagg acaagactac tgtggattca agtgctttaa tgactattta tgcgttgact    840
gtgagaatag ggagcagtgc catgggacat ttctaggtgt agagaaagaa gaaactgcaa    900
tggaaaaatt tgtatgattt ccatttattt cagaaagttt gtatgtaaca attacccgag    960
agtcatttct acttgcaaaa ggattcgtaa caaagcgagt ataattttct tgtcattgta   1020
tcatgcttgt taaattttaa tgcagcatct tcagaacttg tcctgatggt gtcttattgt   1080
gtcagcacca aatatttgtg cattatttgt ggacgttcct tgtcacagga agattcttct   1140
tctgttgcct tattgttttt ttttttttaa gtctcttctc tgtctttgta ctggaatcga   1200
aatcataaga taaacagatc aaacgtgctt aagagctaac tcgtgacact atgcagtatt   1260
gtttgaagac ctgttgttca acctctgtct ctttatgtta actggatttc tgcattaaat   1320
gactgccccc ttgttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaactcgta    1379

<210> 1213
<211> 1482
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1482)
<223> n equals a,t,g, or c

<400> 1213
cggggaggat gaggaagatg aagacgaggc ctggaactgt caagcggtgg ctggacggag     60
atgcctggga tcctgtggat ggagcctacg cagccgcctg actttgccct ggcctataga    120
ccgagcttcc cagaggacag agagccacag ataccctacc cggagcccac ctggccaccc    180
ccgctcagtg cccccagggt cccctaccac tcctcagtgc tctccgtcac ccggcctgtg    240
gtggtctctg ccacgcrtcc cacactgcct tctgcccacc agcctcctgt gatccctgcc    300
acacacccag ctttgtcccg tgaccaccag atccccgtga tcgcagccaa ctatccagat    360
ctgccttctg cctaccaacc cggtattctc tctgtctctc attcagsaca gcctcctgcc    420
caccagcccc ctatgatctc aaccaaatat ccggagctct tccctgccca ccagtccccc    480
atgtttccag acacccgggt cgctggcacc cagaccacca ctcatttgcc tggaatccca    540
cctaaccatg cccctctggt caccaccctc ggtgcccagc taccccctca agccccagat    600
gcccttgtcc tcagaaccca ggccacccag cttcccatta tcccaactgc ccagccctct    660
ctgaccacca cctccaggtc ccctgtgtct cctgcccatc aaatctctgt gcctgctgcc    720
acccagcccg cagccctccc caccctcctg ccctctcaga gccccactaa ccagacctca    780
cccatcagcc ctacacatcc ccattccaaa gccccccaaa tcccaaggga agatggcccc    840
agtcccaagt tggccctgtg gctgccctca ccagctccca cagcagcccc aacagccctg    900
ggggaggctg gtcttgccga gcacagccag agggatgacc ggtggctgct ggtggcactc    960
ctggtgccaa cgtgtgtctt tttggtggtc ctgcttgcac tgggcatcgt gtactgcacc   1020
cgctgtggcc cccatgcacc caacaagcgc atcactgact gctatcgctg ggtcatccat   1080
gctgggagca agagcccaac agaacccatg ccccccaggg gcagcctcac aggggtgcag   1140
acctgcagaa ccagcgtgtg atggggtgca gacccccctc atggagtatg gggcgctgga   1200
cacatggccg gggctgcacc agggacccat gggggctgcc cagctggaca gatggcttcc   1260
tgctccccag gcccagccag ggtcctctct caaccactag acttggctct caggaactct   1320
gcttcctggc ccagcgctcg tgaccaagga tacaccaaag cccttaagac ctcagggggc   1380
gggtgctggg gtcttctcca ataaatgggg tgtcaacctt aaaaaaaaaa aaaaaaaaaa   1440
actcgagggg gggcccgtac ccaattcgcc atatagtgcc cn                      1482

<210> 1214
<211> 4721
<212> DNA
<213> Homo sapiens

<400> 1214
ccacgcgtcc ggacagaggc tggagaaggc tggagaagga tgtatggcct gccctgggct     60
tgtctgttcc ctcctgagcc tgagcccctt accttcctga ccccatgaag cacacactgg    120
ctctgctggc tcccctgctg ggcctgggcc tggggctggc cctgagtcag ctggctgcag    180
gggccacaga ctgcaagttc cttggcccgg cagagcacct gacattcacc ccagcagcca    240
gggcccggtg gctggcccct cgagttcgtg cgccaggact cctggactcc ctctatggca    300
ccgtgcgccg cttcctctcg gtggtgcagc tcaatccttt cccttcagag ttggtaaagg    360
ccctactgaa tgagctggcc ttcgtgaagg tgaatgaggt ggtgcggtac gaggcgggct    420
acgtggtatg cgctgtgatc gcgggcctct acctgctgct ggtgcccact gccgggcttt    480
gcttctgctg ctgccgctgc caccggcgct gcgggggacg agtgaagaca gagcacaagg    540
cgctggcctg tgagcgcgcg gccctcatgg tcttcctgct gctgaccacc ctcttgctgc    600
tgattggtgt ggtctgtgcc tttgtcacca accagcgcac gcatgaacag atgggcccca    660
gcatcgaggc catgcctgag accctgctca gcctctgggg cctggtctct gatgtccccc    720
aagagctgca ggccgtggca cagcaattct ccctgcccca ggagcaagtc tcagaggagc    780
tggatggtgt tggtgtgagc attgggagcg cgatccacac tcagctcagg agctccgtgt    840
accccttgct ggcggccgtg ggcagtttgg gccaggtcct gcaggtctcc gtgcaccacc    900
tgcaaacctt gaatgctaca gtggtagagc tgcaggccgg gcagcaggac ctggagccag    960
ccatccggga acaccgggac cgcctccttg agctgctgca ggaggccagg tgccagggag   1020
attgtgcagg ggccctgagc tgggcccgca ccctggagct gggtgctgac ttcagccagg   1080
tgccctctgt ggaccatgtc ctgcaccagc taaaaggtgt ccccgaggcc aacttctcca   1140
gcatggtcca ggaggagaac agcaccttca acgcccttcc agccctggct gccatgcaga   1200
catccagcgt ggtgcaagag ctgaagaagg cagtggccca gcagccggaa ggggtgagga   1260
cactggctga agggttcccg ggcttggagg cagcttcccg ctgggcccag gcactgcagg   1320
aggtggagga gagcagccgc ccctacctgc aggaggtgca gagatacgag acctacaggt   1380
ggatcgtggg ctgcgtgctg tgctccgtgg tcctattcgt ggtgctctgc aacctgctgg   1440
gcctcaatct gggcatctgg ggcctgtctg ccagggacga ccccagccac ccagaagcca   1500
agggcgaggc tggagcccgc ttcctcatgg caggtgtggg cctcagcttc ctctttgctg   1560
cacccctcat cctcctggtg ttcgccacct tcctggtggg tggcaacgtg cagacgctgg   1620
tgtgccggag ctgggagaac ggcgagctct ttgagtttgc agacacccca gggaacctgc   1680
ccccgtccat gaacctgtcg caacttcttg gcctgaggaa gaacatcagc atccaccaag   1740
cctatcagca gtgcaaggaa ggggcagcgc tctggacagt cctgcagctc aacgactcct   1800
acgacctgga ggagcacctg gatatcaacc agtataccaa caagctacgg caggagttgc   1860
agagcctgaa agtagacaca cagagcctgg acctgctgag ctcagccgcc cgccgggacc   1920
tggaggccct gcagagcagt gggcttcagc gcatccacta ccccgacttc ctcgttcaga   1980
tccagaggcc cgtggtgaag accagcatgg agcagctggc ccaggagctg caaggactgg   2040
cccaggccca agacaattct gtgctggggc agcggctgca ggaggaggcc caaggactca   2100
gaaaccttca ccaggagaag gtcgtccccc agcagagcct tgtggcaaag ctcaacctca   2160
gcgtcagggc cctggagtcc tctgccccga atctccagct ggagacctca gatgtcctag   2220
ccaatgtcac ctacctgaaa ggagagctgc ctgcctgggc agccaggatc ctgaggaatg   2280
tgagtgagtg tttcctggcc cgggagatgg gctacttctc ccagtacgtg gcctgggtga   2340
gagaggaggt gactcagcgc attgccacct gccagcccct ctccggagcc ctggacaaca   2400
gccgtgtgat cctgtgtgac atgatggctg acccctggaa tgccttctgg ttctgcctgg   2460
catggtgcac cttcttcctg atccccagca tcatctttgc cgtcaagacc tccaaatact   2520
tccgtcctat ccggaaacgc ctcagctcca ccagctctga ggagactcag ctcttccaca   2580
tcccccgggt tacctccctg aagctgtagg gccttgtggg gtgaggtgac cctgaggctg   2640
cctgtcctcc cctttgattt agcctgggcc acaggacttc ggtagctctt gccccagagc   2700
ccaggctggc atccaggcct ggactgtccc cagttccggc ttacctggcc ccaccttgcc   2760
tgctcctttc cacccctttc tgctcacgac ccccatcatt cacgctcaga atcacatggg   2820
acttctgtgc agctgcagag ccagcaagtc cctccaggtg tcacccctta cccccatgct   2880
ggtggcatcc tcacaggaag agcctgttct ccacctgctg gagcctggac cctggggtgg   2940
gacagaggcc tcgtccaacc ccactcccct tcccgtgtgt cttccccctg ccaagcctcc   3000
ccctgccaag cctccccctg cccctctctg agcccctcgc cccccacacc gtcctcatct   3060
ggcctccccc ctggccccca cttccctctt atgcccttcc tggccctttg cttcctccct   3120
tagtcccctc ttcaccatat ctccactgct accttgctgg ccccagagac caccctgccc   3180
aaccaaacca ctcaggtaac gccactaatc aggcaggggc caccatggcc taggtctggg   3240
ctggctgcag gccctgcctc atggcctctg agccctccac tgccccaggg ccttgggccc   3300
tctgcagatc tcatccagga tttattggtg tccagtgggg tgagggaggc ctgtctgaag   3360
gccgagcctc cctgcctgca cccaagttag aaatgggggt accagcactt agcttctctc   3420
tgagtgctgg ctcccaagga agggacctgg gacctgggcc acagtggggg cttgccctta   3480
cctcttcaga aggaagcatc ttccacagcc cccacccaac tttcttagga gtgatctggt   3540
ggccagaaca ggattttgca cggccccttt tatcctgcgc atgtggccta gggtcatccc   3600
cagcccatcc ctgtgtcagc cctgagtgct ggacactgcg ttccagaaat gaggaagagg   3660
agagagaaga gatggacaga cctcagatcc attaaagtgt tctcacttcc ctgagacttg   3720
gttctgggtc cttaaaacca ggtttcctag gctgggaccc tgtacatagt tggtgtttaa   3780
tgagtgttta tggagaggag agttctaagg tcacctctgg ctgcaggcat ccagggatta   3840
ttccagcaat ctgcaggtag ggagtgggtc ccagcctggg agcctgctgt caggagcagg   3900
cagacctgga ctcacagcct ggctgtgatg cttgttcgct cagcttctcc atttatgaga   3960
tggggagaat agtcacagcc tcctcaaagg gttgtgaaaa tcaaatgtga taatttgtgg   4020
aaagccctta gcagtggcct ggcacaaaac aaatgctcag tggatggaag ctgcctatta   4080
ttattgtcgt tgttgttgtt tgccatgact gctctgggcc gggggtagag ctagcatccg   4140
ggcatgtacg agggaagagg gaggcaggcc tctattcaaa ggcagaaatt cctttaagat   4200
tgtggtctgc tgggtttcag ggagtgtctg tgttgtttgt ttttgtttgt ttgtttgttt   4260
tgagacaggg tctcgctctg tcacccaggc tggagtgtag tggtgcagtc ttggctcact   4320
gcaacctcca cctcctgggc tcaagcgatt ctcatgcctc agcctcccga gtagctggga   4380
ctacaggtgt gtgccactat gcctggctaa tttttgtatt ttttgtagag acggggtttt   4440
gccatgttgc ccaggctgga agtgtctatg tttaactgca tcttataaac cagcaacaag   4500
ttttctactg ggaattagaa tggtgcatac acaatgtatt attatcactg tcagatgagc   4560
atgcttgaat gtagcatgac tgcctctttt tgcttttcct agaggttttt ttttttgctt   4620
gttactcatc tgttgaccta cctgggggaa gtagcaccct tgcatttcaa aaataaaatt   4680
gatggcatta caaaaaaaaa aaaaaaaaaa aaaaaaaaaa a                       4721

<210> 1215
<211> 958
<212> DNA
<213> Homo sapiens

<400> 1215
cctatagaag gacttctgca ggtaccggcc cggaattccc gggtcgaccc acgcgtccgt     60
ggcttgtcgc gaatcttcat cttagcacat ttccctcacc aggtgctggc tggcctaata    120
actggcgctg tcctgggctg gctgatgact ccccgagtgc ctatggagcg ggagctaagc    180
ttctatgggt tgactgcact ggccctcatg ctaggcacca gcctcatcta ttggaccctc    240
tttacactgg gcctggatct ttcttggtcc atcagcctag ccttcaagtg gtgtgagcgg    300
cctgagtgga tacacgtgga tagccggccc tttgcctccc tgagccgtga ctcaggggct    360
gccctgggcc tgggcattgc cttgcactct ccctgctatg cccaggtgcg tcgggcacag    420
ctgggaaatg gccagaagat agcctgcctt gtgctggcca tggggctgct gggccccctg    480
gactggctgg gccacccccc tcagatcagc ctcttctaca ttttcaattt cctcaagtac    540
accctctggc catgcctagt cctggccctc gtgccctggg cagtgcacat gttcagtgcc    600
caggaagcac cgcccatcca ctcttcctga cttcttgtgt gcctcccttt cctttccctc    660
ccacaaagcc aacactctgt gaccaccaca ctccaggagg cagccccatc cccttccagc    720
ccctaagtag gccctcccct ccctaaatct gcttccgcac cacctggtct tagccccaaa    780
gatgggcctt ctctctccca gataagttgg tcctccctct gcctttcctc tcaagccccc    840
aaagagcaaa ggcaacagca agaccagcgg gttcttgcaa cactgtgagg ggcagccagg    900
gcggccccaa taaagccctt gaatactttr aaaaaaaaaa aaaaaaaaaa aaaaaaaa      958

<210> 1216
<211> 2337
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> n equals a,t,g, or c

<400> 1216
ccccgcctac ctcactaaag ggaacaaaag ctggagctcc accgcggtgg cggccgctct     60
agaacnagtg gatcccccgg gctgcctggg accgtctctt ctatcgtggt gtttttcacc    120
atgcgcattg gtacctcgat tatctctgcc gccagcctct catttctcgg cctcggtgcg    180
cascgccgac accagagtgg ggagcaatgc tcaatgaggc tcgagcggat atggttatcg    240
cgccgcatgt cgctgttttt ccggccctgg ctatttttct gaccgtactg gcgttcaatt    300
tgttgggcga tggtttacgc gatgcgctgg atccgaaaat taaaggatag ttacgtttga    360
atattgcttg aaagggtaat cacctcacag gaaattattg ccctaagcaa gtgttgtaac    420
tttctgctga ttttgtagaa tcgggtaatt tggttaaaaa gccgcagcaa gggacaattt    480
ttgcagcggc acagcgttca gatagttatt ttgttaaatg tattaacatg ctgagtttat    540
acgaaaagat aaagataagg ctgataattt tatttttatt ggcagcactg tcatttattg    600
gtcttttttt catcattaac tatcaactgg tatcggagcg cgcggtaaaa cgtgccgata    660
gccgctttga acttattcag aaaaacgttg gctatttctt taaagatatt gaacgttcgg    720
ccctgacatt aaaggactca ctgtatttat taaaaaatac agaggagatt caacgcgccg    780
tgattcttaa aatggaaatg atgccatttt tagactcggt gggactggta cttgatgata    840
ataaatatta tcttttttcg cggagggcga atgataaaat cgttgtttat catcaggaac    900
aagtaaatgg accgcttgtc gacgagtcag ggcgggttat ttttgccgat tttaacccat    960
cgaaacgacc gtggtcggtg gcttcagatg actctaacaa cagctggaat ccggcataca   1020
attgctttga tcgtccgggt aaaaaakgga tctcttttac gctacacatc aacggcaaag   1080
atcacgattt gttagcggtg gataaaattc atgtcgattt aaactggcga tatctgaacg   1140
agtatcttga tcaaatcagc gctaatgatg aagttctatt tttgaaacaa ggccatgaga   1200
tcattgccaa gaatcaactc gctcgtgaaa aactgattat ttataatagc gaaggtaatt   1260
ataatattat tgattctgtc gatactgaat atatcgaaaa aacatcagcg gtgccaaaca   1320
acgcattatt cgaaatctat ttttattatc ctggcggtaa tttattgaac gcatcagata   1380
aactttttta tctgccgttt gcgttcatta ttatcgtatt gctggtggtt tatttaatga   1440
ccactcgtgt gttccgtcgg caattttctg aaatgacaga gctggttaat acgctggcgt   1500
ttttgcctga ctcaacggat caaatcgagg ctctgaaaat tcgtgaaggc gatgcgaaag   1560
agattatcag catcaaaaat tcgatcgcgg aaatgaaaga tgccgaaatt gaacggtcaa   1620
ataaattgct ctcactgatc tcttacgatc aggaaagtgg ttttattaaa aatatggcga   1680
ttattgagtc taacmataat cagtatctgg ctgtggggat catcaaactg tgtggtctgg   1740
aagccgtgga agcggtgttt ggtgttgatg agcgcaataa aatcgtcagg aaattgtgtc   1800
agcgaattgc cgagaaatat gcgcaatgct gcgatatcgt gacattcaat gccgatctct   1860
atttacttct gtgtcgggaa aatgtacaga catttacccg taaaatagcg atggtaaacg   1920
attttgacag cagctttggc taccgcaatc tgcgcatcca taagtctgcc atttgtgaac   1980
ctttgcaggg ggaaaacgcc tggagttacg cagaaaaact gaaactggcg atttccagta   2040
tccgtgacca tatgttctca gagtttattt tctgtgatga cgcgaaactc aacgaaatag   2100
aagagaatat ctggattgcg cgtaatattc gccatgcaat ggaaattggc gaactattcc   2160
tcgtctatca accgatcgtt gatattaaca cccgcgccat tctgggcgcg gaggcgttgt   2220
gccgttgggt gtctgcggag cgggggatca tttcaccgct gaagttcatt accattgctg   2280
aagatatcgg gtttatcaat gagctgggtt atcagattat taaaacggca atgggtg      2337

<210> 1217
<211> 1977
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1156)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1247)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1323)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1940)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1970)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1976)
<223> n equals a,t,g, or c

<400> 1217
cgcctgctcc cagacccccg ggagtcgtag gaacccgttc ctggacgctg acgtcggctt     60
tcagggatcc ctcgccggac gccgcggagg gacagagcct gggaagccgt cgccccgccc    120
cgtccccgcc cccgcgcgca gcggcccggg gcgctgagac ccgcgtagag caaagcgcaa    180
ggtcccagcg ccccttggat cctcggtggc agggtccggg caagtgtcat tgcgagggtt    240
caggaagccc cggcctgtga tcgtgagcgg aaacccctcc tggagtttcc ccaaagccat    300
ggacagccct agtcttcgtg agcttcaaca gcctctgctg gagggcacag aatgtgagac    360
ccctgcccag aagcctggca ggcatgagct ggggtccccc ttaagagaga tagcctttgc    420
cgagtccctg aggggtttgc agttcctgtc accgcctctt ccctccgtga gcgctggcct    480
gggggaacca aggccccctg atgttgagga catgtcatcc agtgacagtg actcggactg    540
ggatggaggc agccgtcttt caccatttct accccacgac cacctcggct tggctgtctt    600
ctccatgctg tgttgtttct ggcccgttgg catcgctgcc ttctgtctag cccagaagac    660
caacaaggct tgggccaagg gggacatcca gggggcaggg gccgcctccc gccgtgcctt    720
cctgctgggg gtcctcgccg tcgggctggg cgtgtgcacg tatgcggctg ccctggtgac    780
cctggcygcc taccttgcct cccgagaccc gccctagttg cccctacagc cctcactgtg    840
aaccctgagg ccggcagccc agcaaatctg tgggcagaga gtggagaatc ttggtggatg    900
aggctgcggc ggcggcagga gcatctagaa acgggagcga gctggactgg aacccttccc    960
cttcctggcc accgctcttc gggcggcagc aacctgagat taaacaccag acacccttgc   1020
agccaaaaaa aaaaaaaaaa aaaaaaaaaa raaaaaaaaa aagggcggmc gscctttttt   1080
tttttttttt ttttttttgg tagggataar ggcagttgtg agaaattggg ctaggtaagc   1140
tggcaaatga ccaggncact gaaattgggc aaggttgtct actgaaagtg aagaggtttg   1200
ggatttgagt agagccctga ggagagtggt gaaaggtttg aaattgngtt tgaagaggct   1260
ggaaagagaa ccatctaatg ataagtaaaa ggattggaga gtaatttgta gcggtacaga   1320
ctntgcagtt gtgattacca ttttttttta actcagtgag tggtactcag ccacctgaat   1380
aaaggactaa tgagtatatt ttagtattga ttgaggattc tgtttttgct gggtaggtgc   1440
agtagaaaat atagcagtct aagggaattg aggatgcagt gagagaataa taaattgtga   1500
tggtgagtgc tgaataggga aagacaagaa gccagaaaaa gactgagctt cttaggaaaa   1560
cattaatgga tcacaaactt ggagggctgt atggtttttc atttaagaaa gtaattgtcg   1620
tgcaataaag ttattaagcc ttgtttaaga atatttttat tttgtacatc aagtggagtt   1680
ggaaatagyt ggtttcataa tgatatattt caaaagtatc ttgaagtcat ctggttcatt   1740
tcactaccca gggcacacat tcctcctgta acatcccaag tggttattaa gcaaaacaga   1800
tttattttat ttagaaaaaa ttagtatgac tgatttgcta ttgattttgt acttctataa   1860
taaatgtgat acatgctata ttcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1920
aaaaaaaaaa gggcggccgn tctagaggat ccctcgaggg gcccaagctn acgcgng      1977

<210> 1218
<211> 738
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (473)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (665)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (711)
<223> n equals a,t,g, or c

<400> 1218
tcgagttttt tttttttttt ttttatgtgg ataatattta tttgtatctt atctatagaa     60
caaatattta cagatacaaa cggaatcaca gcaaagttgc tataaaacca tccagacctc    120
tcgatggcca cttctgaaaa catccacggt gaagggcagg gccaggcctg gctgtggagt    180
gggccagctg agtacctccc tcctgtctgg cgggaggctc attctctctc gcagccactc    240
gccctctctg cctctcacat atgcggtcac agagtgaatc cgagcatctt attgctgcag    300
ggggcagggg cgtcggcatc agggaaagtt aatccacgaa gagcgagaac agcaccatta    360
ccacgatgcc cgcacagagc agaagcagct gctgcaggga gcgccacggg tcctcttctt    420
ccaagaggtc agggagcacg ttcaccaagg cgatgtagag aaagccgcca gangtgaagg    480
gcaggaccca ggctgccgtc tcctctactc ccttggggga ctgggtacag atggcgaaca    540
gcggcccakt rggcccccca gcgctgttga ragttgcagc ttkgctggct ccatcggtca    600
aagccggccc ggagcaggat ggcaaagtcg cccacctcat gggggatctc atgcaggagg    660
atggncatgg ttgttaggaa ccccgatttt tctttgcttc acaaggaaag nttggcagcc    720
aacaagccaa gccccgtt                                                  738

<210> 1219
<211> 1409
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1180)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1384)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1392)
<223> n equals a,t,g, or c

<400> 1219
acaggatcta ccccctctgc agcccttcaa gaagaggtat gattgctacc acttttcccc     60
acaaagtgac gaaaggaaac agcgacggaa gcgcaaccga accctggaat tggtgtctcg    120
actggtccat tcccggccca cccccattaa ccggctcgag ccactcccag gacgaagtca    180
aggcctcgga aggcgactac aactcccagc aggtcgagca gctccgcccg cgctgattct    240
ccattggcct tccgggggtg gggattagat gggaggtggc cgtggggctg cggccgggat    300
ttgtcccctc ttcggcttcc gtagaggaag tggcgcggac cttcatttgg ggtttcggtt    360
cccccccttc cccttccccg gggtctgggg gtgacattgc accgcgcccc tcgtggggtc    420
gcgttgccac cccacgcgga ctccccagct ggcgcgcccc tcccatttgc ctgtcctggt    480
caggccccca ccccccttcc cacctgacca gccatggggg ctgcggtgtt tttcggctgc    540
actttcgtcg cgttcggccc ggccttcgcg cttttcttga tcactgtggc tggggacccg    600
cttcgcgtta tcatcctggt cgcaggggca tttttctggc tggtctccct gctcctggcc    660
tctgtggtct ggttcatctt ggtccatgtg accgaccggt cagatgcccg gctccagtac    720
ggcctcctga tttttggtgc tgctgtctct gtccttctac aggaggtgtt ccgctttgcc    780
tactacaagc tgcttaagaa ggcagatgag gggttagcat cgctgagtga ggacggaaga    840
tcacccatct ccatccgcca gatggcctat gtttctggtc tctccttcgg tatcatcagt    900
ggtgtcttct ctgttatcaa tattttggct gatgcacttg ggccaggtgt ggttgggatc    960
catggagact caccctatta cttcctgact tcagcctttc tgacagcagc cattatcctg   1020
ctccatacct tttggggagt tgtgttcttt gatgcctgtg agaggagacg gtactgggct   1080
ttgggcctgg tggttgggag tcacctactg acatcgggac tgacattcct gaacccctgg   1140
tatgaggcca gcctgctgcc atctatgcag tcactgkttn catggggctc tgggccttca   1200
tcacagctgg agggccctyc gaagtattca gcgcagcytc ttgkgaagga ctgactacct   1260
ggactgatcg ctgacagatc acctgctgtc mctgccatga ctgagccagc ccagccggtc   1320
cattgccaaa tctctctttc gcggctaccc atactcaggt ttgttgcctt tggacgtagc   1380
ttanttacag anagctggtc agcagcagt                                     1409

<210> 1220
<211> 3094
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (34)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2498)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3089)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3092)
<223> n equals a,t,g, or c

<400> 1220
nncaancaac gtgctagact ccnctagggt tagntggtac gcccgcaggt accggtccgg     60
aattcccggg tcgacccacg cgtccgcaag gagtgtatct acattttgga agctgctcca    120
cgtcaaagaa tagagttgac ctttgatgaa cattattata tagaaccatc atttgagtgt    180
cggtttgatc acttggaagt tcgagatggg ccatttggtt tctctcctct tatagatcgt    240
tactgtggcg tgaaaagccc tccattaatt agatcaacag ggagattcat gtggattaag    300
tttagttctg atgaagagct tgaaggactg ggatttcgag caaaatattc atttattcca    360
gatccagact ttacttacct aggaggtatt ttaaatccca ttccagattg tcagttcgag    420
ctctcgggag ctgatggaat agtgcgctct agtcaggtag aacaagagga gaaaacaaaa    480
ccaggccaag ccgttgattg catctggacc attaaagcca ctccaaaagc taagatttat    540
ttgaggttcc tagattatca aatggagcac tcaaatgaat gcaagagaaa cttcgttgca    600
gtctatgatg gaagcagttc tattgaaaac ctgaaggcca agttttgcag cactgtggcc    660
aatgatgtaa tgcttaaaac aggaattgga gtgattcgaa tgtgggcaga tgaaggtagt    720
cggcttagca ggtttcgaat gctctttact tcctttgtgg agcctccctg cacaagcagc    780
actttctttt gccatagcaa catgtgcatc aataattctt tagtctgtaa tggtgtccaa    840
aattgtgcat acccttggga tgaaaatcat tgtaaagaaa agaaaaaagc aggagtattt    900
gaacaaatca ctaagactca tggaacaatt attggcatta cttcagggat tgtcttggtc    960
cttctcatta tttctatttt agtacaagtg aaacagcctc gaaaaaaggt catggcttgc   1020
aaaaccgctt ttaataaaac cgggttccaa gaagtgtttg atcctcctca ttatgaactg   1080
ttttcactaa gggacaaaga gatttctgca gacctggcag acttgtcgga agaattggac   1140
aactaccaga agatgcggcg ctcctccacc gcctcccgct gcatccacga ccaccactgt   1200
gggtcgcagg cctccagcgt caaacaaagc aggaccaacc tcagttccat ggaacttcct   1260
ttccgaaatg actttgcaca accacagcca atgaaaacat ttaatagcac cttcaagaaa   1320
agtagttaca ctttcaaaca gggacatgag tgccctgagc aggccctgga agaccgagta   1380
atggaggaga ttccctgtga aatttatgtc agggggcgag aagattctgc acaagcatcc   1440
atatccattg acttctaatc ttctgctaat ggtgatgtga attcttaggg tgtgtacgta   1500
cgcagcctcc agggcaccat actgtttcca gcagccaacc cttttctccc atcacaacta   1560
cgaagacctt gatttaccgt taacctattg tatggtgatg tttttattct ctcaggcagt   1620
ctatatatgt taaaccaatc aaggaactta ctctattcag tggaaacaat aatcatctct   1680
attgcttggt gtcatttata ggaagcactg ccagttaaag agcattagaa gaggtggttg   1740
gatggagcca ggctcaggct gcctcttcgt tttagcaaca agaagactgc tcttgactga   1800
taacagctct gtcaatattt tgatgccaca ataaacttga tttttcttta cattcctttt   1860
atttttcctt tctctaaatt taatttgttt tataagccta tcgttttacc atttcatttt   1920
cttacataag tacaagtggt taatgtacca catacttcag tataggcatt tgttcttgag   1980
tgtgtcaaaa tacagctagt tactgtgcca attaagaccc agttgtattt cacccatctg   2040
tttcttcttg gctaatctct gtacttctgc cttttaatta ctgggccctt attccttatt   2100
ttctgtgaga aataatagat gatatgattt attacctttc aattatattt ttctcagtta   2160
tactagaaaa tttcataatc ctgggatata tgtaccattg tcagctatga ctaaaaattt   2220
gaaaaagata aaaatttcta gcaagccttt gaagtttacc aagtatagtc acattcagtg   2280
acagcccatt cattccagta aagaatcatt tcattcactt tgggagaggc ctataattac   2340
atttatttgc aatgtttctc ttcgctagat tgttacatag ctcccattct gttggttttg   2400
cttacagcat atggtaacca aggttagatg ccagttaaaa ttccytagaa attggatgag   2460
ccytgagatt gcytcytaac ygggacatga catttttnct agctcytatc aagaataaca   2520
actycccact tttttttaaa ctgcactttt gacctttttt tatggtataa aaacaataat   2580
ttataaacat aaaagctcat tgtgtttttt agacttttga tattatttga tactgtacaa   2640
actttattaa atcaagatga aagacctaca ggacagattc ctttcagtgt tcacatcagt   2700
ggctttgtat gcaaatatgc tgtgttggac ctggacgcta taacttattg taaagacctt   2760
ggaaatgtgg acataagctc tttctttcct tttgttactg tatttagttt gtgataaatt   2820
tttcactgtg tgatatttat gctctaaatc actacacaaa tcccatatta aaatatacat   2880
tgtacctgac cctttaatca tgttatttat gccaccaagg ttgtggatct taaggtatgt   2940
atggaaagga actcatttat caaattgtaa gtaatacaga catgccattt aaaagaggta   3000
aattcttgtt ttctatattt tgttagtaaa ttctcaatga aataaaaaaa aaaaaaaaaa   3060
aaaaaaaaaa aaaaaacccc ggggggggnc cngg                               3094

<210> 1221
<211> 3196
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (668)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3170)
<223> n equals a,t,g, or c

<400> 1221
agaatgtttc attaaagtgt ttaattgaag taaatgaaac cataacacag atttcatggg     60
agaagataca tggcaaaagt tcacagactg ttgcagttca ccatccccaa tatggattct    120
ctgttcaagg agaatatcag ggaagagtct tgtttaaaaa ttactcactt aatgatgcaa    180
caattactct gcataacata ggattctctg attctggaaa atacatctgc aaagctgtta    240
cattcccgct tgggaaatgc ccagtcctct acaactgtaa ctgtgttagt tgaacccact    300
gtgagcctga taaaagggcc agattcttta attgatggag gaaatgaaac agtagcagcc    360
atttgcatcg cagccactgg aaaacccgtt gcacatattg actgggaagg tgatcttggt    420
gaaatggaat ccactacaac ttcttttcca aatgaaacgg caacgattat cagccagtac    480
aagctatttc caaccagatt tgctagagga aggcgaatta cttgtgttgt aaaacatcca    540
gccttggaaa aggacatccg atactctttc atattagaca tacagtatgc tcctgaagtt    600
tcggtaacag gatatgatgg aaattggttt gtaggaagaa aaggtgttaa tctcaaatgt    660
aatgctgnat gcaaatccac cacccttcaa atctgtgtgg agcaggttgg atggacaatg    720
gcctgatggt ttattggctt cagacaatac tcttcatttt gtccatccat tgactttcaa    780
ttattctggt gtttatatct gtaaagtgac caattccctt ggtcaaagaa gtgaccaaaa    840
agtcatctac atttcagatc ctcctactac taccaccctt cagcctacaa ttcagtggca    900
tccctcaact gctgacatcg aggatctagc aacagaacct aaaaaattgc ccttcccatt    960
gtcaactttg gcaacaatta aggatgacac aattgccacg atcattgcta gtgtagtggg   1020
tggggctctc ttcatagtac ttgtaagtgt tttggctgga atattctgct ataggagaag   1080
acggacgttt cgtggagact actttgccaa gaactacatt ccaccatcag atatgcaaaa   1140
agaatcacaa atagatgttc ttcaacaaga tgagcttgat tcttacccag acagtgtaaa   1200
aaaaraaaac aaaaatccag tgaacaatct aatacgtaaa gactatttag aagagcctga   1260
aaaaactcag tggaacaatg tagaaaatct caataggttt gaaagaccaa tggattatta   1320
tgaagatcta aaaatgggaa tgaagtttgt cagtgatgaa cattatgatg aaaacgaaga   1380
tgacttagtt tcacatgtag atggttccgt aatttccagg agggagtggt atgtttagca   1440
accactgaat gtgacttaac tatgtacaat gttcattcac actagttgat cattttcaga   1500
ttgttcatac tttttcttga ggaagaataa gctttttcaa gttgattttc aagcttactt   1560
tttatattct aatctgacaa atgaaaatgt aaaatctgag ttcagtgtat ctaagctgct   1620
ttacaatttt ttttcaatgc tgtactactg tctcaagatt taaattttaa tgcagagtac   1680
tttattggtg tgaggcacac aggtaagaag aaatgtcaac attaaatgta tgacttactt   1740
ggtacaaaaa ttttttaaaa agggaactac cttgacattg tgtattaaat gtttacctaa   1800
gactataatc tcaagtatga tgtttgttta acatatacct ctcaaaattt atcaccactc   1860
aatgacmctg catcaaaatt gactataaaa ctaattcaag aaatatttat atatattttt   1920
taatatacaa aaaatattta gcctgatgga atggctttcc ttttcaaaca ttattttcta   1980
agtttctata caaatgaaat ctttacctct gcatattaat gagccttgcc ataattactg   2040
tagagtggct tttcaaagat attttgttgc actaaaactg tggtagtaaa ctcagtgaac   2100
atgatgtgtg gaagagcata attagctggt caatattttt gtccaaaata cctgcaagag   2160
taataaaata catacctktc raacatgata attattagtt tttttttttc ctttctggaa   2220
catggatttt ggtacattag cagtagcctt attttaatgc tttatgtcct aaacatacta   2280
atagaaatga aaagacscar agagcattyc ggaatackga agtactagtt ttagaaatga   2340
gactttcagc caacaatcta tagaaagaat tttatggacc atcttgtttt agttatttaa   2400
tgttgatgtt gttcaaatgg gtaaatgtac agaaagaaaa ttttagagta aacttggaac   2460
tttggatata actagaaaaa actagattat agaattagtc ggtaacactt gctaatggac   2520
attggcattc atctcctttt tcctcctaag tgtatgtatg tgttttaaga tttctgtttt   2580
tacgrttaaa actggaaaca tgaggttttt tgtttttgtt tttttacata attacatata   2640
ttccttctga atcatttatc ytttgagaaa gaaatgttac ctaaacttca aatgtgcttt   2700
ttgtttgtga ggtaattaaa ttgcttctac agtggaggct tacaaaatta ttgtgacaac   2760
tattttgaag ctgaaaggat agtttttcta ttgctaagtc atttgaaaaa gtgaccattt   2820
tgccagtgaa atgaagtgga agttagtagg agaatcataa attaaatata ttattttgtt   2880
aataaaaagg caaagtagta ggtacttttt aaaccctccc aaccagccct ttctcaatat   2940
tcatcaaatc taaaacattt agggggcaaa attctaacat gttcatggta tcttgcaaat   3000
agtgaaagct ttattctgaa ggattataaa ctagttttct tcattttaac tagcactatt   3060
ttgtggaaat tagaaacctc ttttatttct cttcccaaaa gtaatactta ttataaggct   3120
gtagtatcag gttaaggata cagataaata aagttcactt atatcttctn aaaaaaaaaa   3180
aaaaaaaaaa aaaaaa                                                   3196

<210> 1222
<211> 1690
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (144)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1643)
<223> n equals a,t,g, or c

<400> 1222
cccccccggt ttcgtatgtt gtgtggaatt gtgagcggat aacaatttca cacaggaaac     60
agctatgacc atgattacgc caagntcgaa attaaccctc actaaaggga acaaaagctg    120
gagctccacc gcggtggcgg ccgntctaga actagtggat cccccgggct gcaggaattc    180
ggcrcgaagg ctaagggagt gtggcgggcg gctccgggag ccaacatgcc tcggtatgcg    240
cagctggtca tgggccccgc gggcagcggg aagagcacct actgtgccac catggtccag    300
cactgtgaag ccctcaaccg gtctgtccaa gttgtaaacc tggatccagc agcagaacac    360
ttcaactact ccgtgatggc tgacatccgg gaactgatcg aggtggatga tgtaatggag    420
gatgattctc tgcgattcgg tcccaacgga ggattggtat tttgcatgga gtactttgcc    480
aataattttg actggctgga gaactgtctt ggccatgtag aggacgacta tatccttttt    540
gattgtccag gtcagattga gttgtacact cacctgcctg tgatgaaaca gctggtccag    600
cagctcgagc agtgggagtt ccgagtctgt ggagtttttc ttgttgattc tcagttcatg    660
gtggagtcat tcaagtttat ttctggcatc ttggcagccc tgagtgccat gatctctcta    720
gaaattccgc aagtcaacat catgacaaaa atggatctgc tgagtaaaaa agcaaaaaag    780
gaaattgaga aatttttaga tccagacatg tattctttat tagaagattc tacaagtgac    840
ttaagaagca aaaaattcaa gaaactgact aaagctatat gtggactgat tgatgactac    900
agcatggttc gatttttacc ttacgatcag tcagatgaag aaagcatgaa cattgtattg    960
cagcatattg attttgccat tcaatatgga gaagacctag aatttaaaga accaaaggaa   1020
cgtgaagatg agtcttcctc tatgtttgac gaatattttc aagaatgcca ggatgaatga   1080
agagtttact aaaagtaacc atctaaagag cttgtggcca aaccagcaga acattcttct   1140
cttcaaagga tgcaatagta gaaagctact tattttaatg aaaaaaagta aaacttcgtt   1200
ctttatcagc ctcatgcctg aatcaaattt ttaattattc tgaaactgct gctgtttaaa   1260
gtggaatctt ttagtattat aacagcatca ctttagattt tgtaagtcaa aattgaaatg   1320
aatgcacata gatttatata taaattagca cctgagctaa ggttaaggct ggtctaaact   1380
tattttcact ttttgtatta tttttgagat gcaggaatta ctgtaacaaa atatgtatgt   1440
ccgaagggaa aaagctgcaa ggatatatat aagaccactg cttatctgta tcttcccatt   1500
ttcctatatt gaaaatgtat attatttata taacttaaaa agtaaaaata actatgtttt   1560
gaaaaaaaaa aaaaaaaaaa ctcgaggggg ggcccgtacc caattcgccc tatagtgatc   1620
stattmcaat tcactggccg tcnttttaca acgtccgtga ctgggaaaac ctggcgttcc   1680
ccacttaatc                                                          1690

<210> 1223
<211> 1630
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1557)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1601)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1610)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1624)
<223> n equals a,t,g, or c

<400> 1223
ttttgcaaaa agctatttag gtgacactat agaaggtacg cctgcaggta ccggtccgga     60
attcccgggt cgacccacgc gtccgcggac gcgtgggtgg ccgctcgccg cccgcccgcc    120
cgacggagac gcatcccagc tatctgactt catgtgaaag atggctaatg cagaagtgag    180
tgtcccagtg ggggatgtgg ttgtggtacc tactgaagga aatgaagggg agaatcctga    240
agacactaaa acccaagtga ttttgcagtt acagcctgtg caacaaggga tttatgaagc    300
tgggtcggag aacaacacgg cagttgtagc agtagaaact cacacgatac acaaaattga    360
agaagggatt gatacaggca ctatagaagc aaatgaggat atggaaattg cttaccccat    420
aacttgtggg gagagcaaag ccatcctcct ctggaagaag tttgtatgtc caggaataaa    480
cgtgaagtgt gtcaagttca atgatcagtt gatcagcccc aagcactttg ttcatctggc    540
tggcaagtcc actctgaagg actggaagag agctattcgt ctgggtggga tcatgctcag    600
gaaaatgatg gactccggac agattgattt ttaccaacat gacaaagttt gctccaatac    660
ctgcagaagc accaaatttg atcttctgat cagcagtgca agagctccag tgccaggaca    720
gcagacaagt gtkgtgcaga cacccacttc ggctgatggt agcatcacgc agattgccat    780
ctcagaagag agcatggaag aggcagggct ggaatggaac tcagctctca ccgctgctgt    840
caccatggcc acggaggagg gtgtaaagaa agactcagag gaaatttcag aggacacttt    900
gatgttctgg aaaggaatag ctgatgtagg gctgatggaa gaggttgtct gcaatataca    960
gaaggaaata gaggagctac tcaggggagt tcagcagcgg ctcatccagg ctcccttcca   1020
agtcacagat gctgctgttc tcaacaatgt agcacacaca tttggcctaa tggacacagt   1080
caagaaggtt ttagacaaca gaaggaacca agtagagcag ggagaagaac agtttctcta   1140
tactctgaca gacttggaac gccagttgga ggagcagaag aagcaaggcc aggatcacag   1200
gctgaaatct cagacagttc aaaatgtggt actgatgcct gtgagcactc ctaagcctcc   1260
aaaaaggccc cggctccagc ggccagcctc caccactgtc ttgagccctt ctcctcctgt   1320
ccagcagcct cagttcacag tcatctyacc cattcaccat caccccagtg ggktcagtca   1380
tttttccatk gggcaatatt tccartgggc caccctyagc caggggctcc agttcctgtg   1440
gactgtycca cacattgcct ttttgggcct tcaggttttt tccgttatgg ccacagtggg   1500
gttttccttt tggccaagga ggcaggtttt aaccaggaca cagttgaacc attccancct   1560
ttcattttag gtttgggggg ttgtttgagg tttttatttg ncatgagggn tgggggggtt   1620
aaantggggt                                                          1630

<210> 1224
<211> 1335
<212> DNA
<213> Homo sapiens

<400> 1224
agaaaaagaa gataaagaga aaaagaggga agaattgaaa aaaattgttg aagaagagag     60
actaaagaaa aaagaagaaa aagagaggct taaagtagaa agagaaaagg aaagagagaa    120
gttacgtgaa gaaaagcgaa agtatgtgga atacttaaaa cagtggagta aacctagaga    180
agatatggaa tgtgatgacc ttaaggaact tccagaacca acaccagtga aaactagact    240
acctcctgaa atctttggtg atgctctgat ggttttggag ttccttaatg catttgggga    300
actttttgat cttcaagatg agtttcctga tggagtaacc ctagaagtat tagaggaagc    360
tcttgtagga aatgacagtg aaggcccact gtgtgaattg ctttttttct tcctgactgc    420
aatcttccag gcaatagctg aagaagaaga ggaagtagcc aaagagcaac taactgatgc    480
tgacaccaaa gatttaacag aggctttgga tgaagatgca gaccccacaa aatctgcact    540
gtctgcagtt gcatctttgg cagctgcatg gccacagtta caccagggct gcagtttgaa    600
aagtttggat cttgatagct gcactctttc agaaatcctc agactgcaca tcttagcttc    660
aggtgctgat gtaacatcag caaatgcaaa gtatagatat caaaaacgag gaggatttga    720
tgctacagat gatgcttgta tggagcttcg tttgagcaat cccagtctag tgaagaaact    780
gtcaagcacc tcagtgtatg atttgacacc aggagaaaaa atgaagatac tccatgctct    840
ctgtggaaag ctactgaccc tagtttcaac tagggatttt attgaagatt atgttgatat    900
attacgacag gcaaagcagg agttccggga attaaaagca gaacaacatc gaaaagagag    960
ggaagaagca gctgccagaa ttcgtaaaag gaaggaagaa aaacttaagg agcaaagcta   1020
ctaaagaaag agataaactt ttgaaacaag aagaaatgaa gtcactggct tttgaaaagg   1080
ctaaattaaa aagagaaaaa gcagatgccc tagaagcgaa gaaaaaagaa aaagaagata   1140
aagagaaaaa gagggaagaa ttgaaaaaaa ttgttgaaga agagagacta aagaaaaaag   1200
aagaaaaaga gaggcttaaa gtagaaagag aaaaggaaag agagaagtta cgtgaagaaa   1260
agtcaaaata tatgtgtaat atttaattat tttataagtt ttataataaa gtattccatt   1320
tctttaaaaa aaaaa                                                    1335

<210> 1225
<211> 1474
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (949)
<223> n equals a,t,g, or c

<400> 1225
tctgntcgcc gtcgccccgc ccctggcctt tgcccggtcg ggcgggactt cctgtgtcgt     60
atttccaagg actccaaagc gaggccgggg actgaaggtg tgggtgtcga gccctctggc    120
agagggttaa cctgggtcaa atgcacggat tctcacctcg tacagttacg ctctcccgcg    180
gcacgtccgc gaggacttga agtcctgagc gctcaagttt gtccgtagtc gagagaaggc    240
catggaggtg ccgccaccgg caccgcggag ctttctctgt agagcattgt gcctatttcc    300
ccgagtcttt gctgccgaag ctgtgactgc cgattcggaa gtccttgagg agcgtcagaa    360
gcggcttccc tacgtcccag agccctatta cccggaatct ggatgggacc gcctccggga    420
gctgtttggc aaagatgaac agcagagaat ttcaaaggac cttgctaata tctgtaagac    480
ggcagctaca gcaggcatca ttggctgggt gtatggggga ataccagctt ttattcatgc    540
taaacaacaa tacattgagc agagccaggc agaaatttat cataaccggt ttgatgctgt    600
gcaatctgca catcgtgctg ccacacgagg cttcattcgt tatggctggc gctggggttg    660
gagaactgca gtgtttgtga ctatattcaa cacagtgaac actagtctga atgtataccg    720
aaataaagat gccttaagcc attttgtaat tgcaggarct gtcacgggaa gtctttttag    780
gataaacgta rgcctgcgtg gcctggtggc tggtggcata attggagcct tgctgggcac    840
tyctgtagga ggcctgctga tggcatttca gaagtactct ggtgagactg ktcaggaaag    900
aaaacagaag gatcgaaagg cactccatga gctaaaactg gaagagkgna aggcagacta    960
caagttaytg agcacctycc tkagaaaatt gaaagtagtt tmcaggaaga tgaacytgag   1020
aatgatgyta agaaaattga agcactgcta aaccttccta gaaacccttc agtaatagat   1080
aaacaagaca aggactgaaa gtgctctgaa cttgaaactc actggagagc tgaagggagc   1140
tgccatgtcc gatgaatgcc aacagacagg ccactctttg gtcagcctgc tgacaaattt   1200
aagtgctggt acctgtggtg gcagtggctt gctcttgtct ttttcttttc tttttaacta   1260
agaatggggc tgttgtactc tcactttact tatccttaaa tttaaataca tacttatgtt   1320
tgtattaatc tatcaatata tgcatacatg aatatatcca cccacctaga ttttaagcag   1380
taaataaaac atttcgcaaa agattaaaaa aaaaaaaaaa aaagggcggc cgctctagag   1440
gatccctcga ggggcccaag cttacgcgtg catg                               1474

<210> 1226
<211> 2729
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (695)
<223> n equals a,t,g, or c

<400> 1226
tttttttttt tttttttttt tttttttttt tttttttaag cttcagacgg gtaatacata     60
tttattgaaa attttcttca ccgacaatgg tgaaatcaag acctcaaatt acaaaacatg    120
gtggcaggtg atacttacaa aaataaagcg aaggtctatg ttttacagat ttgtgcatgt    180
ttccttcaaa tctcagtctg tactgtcatt aaaaagatca tggaatctat gttgttcctc    240
atgatggaat agtaaaaaaa ctgcattcca ctgacaaaaa aaatagcttt gcttccaaat    300
agcacaagtc tttaaagtga cttttcccaa caataaatat agaaaatagc ctttaacaag    360
cgtcttttag cttggtcagg gttgtatcat ttgtttggaa agtacatcct tcccctgcag    420
tcagaagacc ccagacagcc tttccagttc tcccgagtct ttggtgcgca cagctgccgg    480
cgggaagtct cactggcggc agagccacta agtccctctg acgggatcca caggaatctt    540
ctcgatgtac caggagcctc tgcccatcac aggagggcag gcccatgtag aacagactct    600
aacaaacctg cagctggaaa ctggatccct tttaaaccag ccgccaccac agctcggctc    660
acccaccagc gccgtccgtg aaggctctct ctggncctca cggtcagcca ggctgccggt    720
cacaccgaag gggtctttgg cgggtgaacc tgctgcatga gctgcgggcg cttcaccctg    780
ggcttcctcc gcttcggcct gctcttggcc ttgttgattt gtaccacaaa gaaggccagg    840
accaccatgg ctcccaggaa ggcaaagaca ggaatggtct ggcccacctc ctggttgtag    900
cggccaggca tgatccctcc aggaatgtcc caggcgccgc tctctccagg ggacaagggc    960
ctcacttgag ggcgattcga tcgaaagttg ggtaacacca ccttgtccag gtcaatggag   1020
agtagcttct gatgtttcca aaggttactg ggcgccgtct cgtttaaagg ctgtggcttg   1080
gcccaagaca agcgtggaca ggctggtaga ggccgaggtt ttgggtctcc caaatgggcc   1140
tccagaacct tggagtaccg atgaagatgg tttccttcca tcctctctgg agtgactgag   1200
cctgctccac tgggagggcg ctggcggttc ccagagtgac tgaggctagg cggtgtcacc   1260
ccatacgatg tgtactggag gagggcatcc agaagccaaa agcagtcctt ctgtcggtga   1320
ctgtcatcca agcaattgga gtccccatac agtacaatcc ggcctccacc ctcagctgga   1380
atctgataaa gtcccaaaat ggggacgttt tcaacaactg ctgtttcctg ctttaaaacc   1440
tccaatcctt ggtccttgaa agtctgtgtt atcacgacgc catcttctgg aaacttcgcg   1500
atgctgcacc ctgacgcata atacatgtca tggttggcca gggtgaactc cccttcatac   1560
aggccatcgc tgaaccccat gttccacaca gacagcagct cattcagagc tgggatgtta   1620
gctcctccgg tatccggcat ccaccactgc cttgtgtttt catcataaaa cttcactttt   1680
ytcataacag aagtgttgta ccagtcactg aagatgacga gcgagaggcc gttgtccacg   1740
tccctccgga gcttggcgat ctcttcaggg aagtactcct cctcactgtc caccatcagc   1800
aaagtgccat actgactggc atcaaaacac gtgaaggggg ccccgaggac ctctacaaag   1860
tagcccatgc ttctcagatg ctggtacata tccctgaaat tggtgtggat gtgatcacca   1920
ttccagtcta aagggtcatt cttcatcctt aaattatcmc tggggaaata gccaggtgga   1980
tagcggaggt tgtggtactg atcccagaga actctcttgc ttcgcggggg agtaggaatt   2040
atcttcacct taatggggag ctttactgtt gaagtctgtt ctgcaccatt ttttgactct   2100
gtctctgctg gggaagccac agtgatcatg acatggccct gagcaatgcc ttcccaggaa   2160
gccgctttct tggtcacaga aatggagatg gccaggtagc ccgaccaagg ccataagacc   2220
gaggagtagg agaaggcaac ttcaatgttg tctccgttct gtggcaaata gggctgccag   2280
tcaggcttat ctacaattct tcctgtgact cccatgccgt tgaggatggt gacattaaca   2340
actgtcggca ttcctccata gtagatgggc tgggagcagt agggccacat gtagggacac   2400
tcagtcagat ctatgtagct ggggctcaaa cttgcctgtg gcttgtagct gttgaggatc   2460
tgataggctc tragcagatc gagcttgccg tggccttgct caaacatgtt gaccccgggg   2520
agcctccggg ctgacgcgat cagggcmtgc ttcatactgg cgggattcac cagctcacgc   2580
ttctggactg tgctcactaa caaggtgaca gcacctgcaa ccactggaga agcaacactg   2640
gtccctgaga gggcccggca cccccctttc acgccagaac cccgcacgcc agcaccatag   2700
gtgacaatgt caggtttcat gcgaccgtc                                     2729

<210> 1227
<211> 876
<212> DNA
<213> Homo sapiens

<400> 1227
tttttttttt tttttttttt ttttttttag aagaaaagag aagttacttt attacaattt     60
gttatctcat cccgaggtca gggccccttg cttagtggga aaaaaaaccc tttaggactg    120
agtctcggaa cagcacctgt cctaaaccca acttctctgt gatgcccgga tttcttgatt    180
ttgatccagt agctgctcat tttcctgcct tttacattta ggagattcaa gctctgtcat    240
ttcctctagc tgcccctgaa gtccgtcctt cctgcagggc ccaactccac gtagagtgag    300
tgcagccaca cagcagtaac cagatagagc agcctcccct gcagacatga gcaaagaagg    360
gatccagaga gccaaggctg tatcatagat tcttgtgggg tcaaaggggc agtcagtatg    420
tcccggcccc tcatccagtg gtaccagagg atccagcagt cctgggtggc agtcagcaat    480
aaggcggcgg ccaccgttgg ccacagtgag tgacacagca agaaggaggc ccagggagca    540
ggcaacggac aagagcaggt tcaccagagc tagtgccagc aggacccagt gcagtggagg    600
gcgaagaagg ttcctggacg ccaggagggc cacaagtccc acggaaacgc tcagcagccc    660
cgagccgaca gagatgacat tggctacggt gtactccggc gtgacagcgc cgcggggatt    720
ggccacgtgc cgcaggacgg tgccatgcag cacggccccc agcagcaggt tcacgtggcc    780
caccaagatc agcgcgaggc ccacacgcat cagccgcctg ggcccccggg cggcgtcgaa    840
agcgcagaga ctgcagcgcc tcatcccgtc tgtgcc                              876

<210> 1228
<211> 979
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (967)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (978)
<223> n equals a,t,g, or c

<400> 1228
tggaaaattt cttagttttg ccggatatga agtgaaaagg tgagatgcat cacgcttcgc     60
gcggtgtctg ggcgttcaaa aagggcagta acagcagtgc ggaaatcccg gcggcgatag    120
agataaccac aaaaaatccg ctccagtgcc aggtatcgag tactttcgcc agcggccaac    180
cagcaagcga cgcccccaga taagcaaaca agccgacaaa ccccgtcgcc gcccctgccg    240
cctctttgtg ggaacactct gccgccgcca taccgattaa catctgtggg ccaaagacaa    300
aaaaaccaat ggtgaagaag caggttgcct gcatcacgta gctggcaaat ggcatcagcc    360
acagggagcc gactgaaagc aaaattccgg cggcgaaaat caaattcatc ggccctcggt    420
tgccgttaaa caatttgtcc gagccccaac cggctaccag cgcaccgata aatccgccca    480
gttcaaacat cgtcactgcc gtattcgccg tgaccagatc gacgcccagt gtctcggaca    540
tatacaaatt gccccagtcg ttgatcgccg cccggaccac atagaccagc acatagcaaa    600
acgaaagcag ccagatatac ggattcagca acacatattt ggtgaggatc tctttacgcg    660
tcaaccctgc cccttcttgt tgttgagcaa tttccagcgc gtcgtgtcgc cattcaccga    720
ccgccggtaa acctaacgcc tgcgggcgat cgcgtagccg ccagcagaga aaaatcccca    780
cgactatcgc catacaacca gcaatcatca tcccggcacg ccagccgtaa tgcagcgcag    840
ccgctgccat cacaatggga atgagtgcgc cgccgacgtt atgcgccgtg ttccataatg    900
cccaggggat ccactagttc tagagcggcc gccaccgcgg tggagckcca gcttttgtta    960
aatttantga ggagtatnt                                                 979

<210> 1229
<211> 857
<212> DNA
<213> Homo sapiens

<400> 1229
tcgagaacta caagttagaa aaggggaaga actgtgttgg ttcaaggccc ccagagaact     60
gttctgtatg agaccctcca tccctagcct actgacagct gacagagaag aaaagtgggt    120
accgccgccc caccactctt taggaggctg aacatcctgg gagctagggg acctgctact    180
aggaggaaac tctaggagga aagcaagcaa atgtctgggg agagacgcca ggatctgcat    240
gtgagtgtgt cagatggaca tgtggctaga atccttttgc ttaagtttgc aattcaaaga    300
aatacagggg ccggacgcag tggctcacgc ctgtaatccc agcactttgg gaggccaagg    360
cgggcggatc acctgaggtc aggagttcaa gaccaacatg gtgaaacccc gcctctacta    420
aaaacacaca aaaaattagc cgggcgtagt ggcgggcacc tgtagtccca gctattcggg    480
aggctgaggc aggagaacgg cgtgaacccg ggaggcggag cctgcagtga gctgagatcg    540
caccactgcc ctccagcctg ggcgactgag cgagactccg tttcaaaaaa aaaggaaaaa    600
agaaatacag aagatagagc ctgtttgtgc ctgcacacct gagagcaggc cacgggaaca    660
tgagattgat gtctttaatc ttgtcagaac ggatagacat tggggcaaag aaatgagtac    720
ggtagagaaa tgtggccacg tattctgcag accccacccc accccccatg ccgactatgt    780
tgcctcgtgc cgaattcctg cagcccgggg gatccactag ttctagagcg gccgccaccg    840
cggtggagcg ccagctt                                                   857

<210> 1230
<211> 1877
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1814)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1840)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1849)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1865)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1875)
<223> n equals a,t,g, or c

<400> 1230
tgcggcaata atgccgttca gattatcgcg cagtcntggt taaaatgacg atcgtggatg     60
atgacatttg cttcgagatt cagtgacaaa ctgagcggat cgagattact ggaccctact    120
gtcgcccagt gatcgtccat caatgccact ttgccgtgga gcgggcggcg gcggtactca    180
aaaacctgaa cgccgccttt aaccagatag ttatacagca agcgcgcacc gactctgaca    240
atcggcatat ccggttcgcc ctgaatgatc agtttgatcc gcaccccgcg ccgtgccgct    300
ttacgcaagg cgtgtaaaaa tcgatagccg gggaagaagt aggcgttggc gataatcact    360
tcccgccgcg cctgagtgag cattttcaaa taatggcgtt caatatcatc gcgatgttct    420
tcgttatcgc gccagaccag caatacctgc gcttctcccg gctggcggtt ctcttccgct    480
ttgtgatgac gtcgccacca gcgtcgtgcc gcgctctgtc caggcaggtt ttccagctca    540
aactggagaa tatcttcgac aatcggccct tcaaggcgta ccgcgtaatc ctgtttagcc    600
tctggaccgt agctggacat atgctcggcg gagtaattca gcccgccaat aaaggctata    660
cgcgcgtcga tcaccacaat tttgcgatgc atccggcgaa acacattggt gcgcatacca    720
aaaaggcgag ggcggggatc gtagtagcgg aacactacgc cagctgccgt cagttcattg    780
acaaactcat cgctgagatc cggcgaaccg tagccatcca gcaagacttc cgctttaacc    840
ccgcgttgcg ctgctgccag tagtgccgca tgcagttgtt tgccgacgtc atcctcaaac    900
cagataaacg tttcaagaat gatgcgttct tgtgcctcgc caatcgcctt aaacaccgcg    960
ggataatatt gctcgccgtt ttccagcaac tggatcttat tgccttcgcg ccagctacat   1020
ttcataaatg aatctccgca cttaaagggg catgatcaga aaggtgtcgc catgtccgca   1080
gcggcaacgc ggttggcgcg ctggcgctgg catttttgac gtagatcctg tccagtcgta   1140
gtagaggaaa ttgcaccgga aacgtgcgcg ccgggcgtcc gtgggcgcgg gtaaaaatct   1200
catccagtcc ggcctgcact tttaacggat gattagcttt ttgccgccag tcattgaaat   1260
cacccgccac caataccggt tcgccgtccg gtagctcatt cacccattcg gcgagcatcg   1320
caagctgcgc ctgacggtgc gcctcacgca ggcccagatg tacgcacatc acatgaatcg   1380
cttttccggt catcggcggc acaatgcggc agtagagcac gccgcgcttt tccgcaccat   1440
cgaccgaaac atcgcgattc tcataatgtt caatgggata acgcgacagt acggcgttgc   1500
cgtgatgccc ttccgggtat acggcattgc gaccgtaggc aaaatcgctc cacatagtgt   1560
cggcgagaaa ctcgtagtgc gaggtatcgg gccagttttc cacatgcagc ggatgaactt   1620
cgtgcgcgcc catcacttcc tgcaggcaaa caatatcggc gctgacggta cgcacggcgt   1680
cgcgaagttc cggcaaaatg aagcgtcggt taaacgcggt aaagcctttg tgaatattga   1740
tggtgagcac cttgaacgaa aattgttgtg tttgatckgg cataattttc ctgctttgcc   1800
tcttatctca ttgnaatagt gtagtcggcg tcacaaaaan ggtgcggcnt tacggaattt   1860
ttccnaaaag tcggnac                                                  1877

<210> 1231
<211> 1183
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (968)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1074)
<223> n equals a,t,g, or c

<400> 1231
gtgcgtgggt ccggctttcg gtgactagac ggtccgcagg gacatcccgt ccctggggcc     60
tccccagtct ccctccccct cgcgcctggg cagctctctc ccagggcttc ggctcgagcc    120
tgcgacctgc acggacaccc ccccctcagg atctaaaatg tccactgagg cacaaagagt    180
tgatgacagt ccaagcacta gtggaggaag ttccgatgga gatcaacgtg aaagtgttca    240
gcaagaacca gaaagagaac aagttcagcc caagaaaaag gagggaaaaa tatccagcaa    300
aaccgctgct aaattgtcaa ctagtgctaa aagaattcag aaggaacttg cagaaatcac    360
attggaccct cctcccaact gtagtgctgg acccaaagga gacaacattt atgaatggag    420
gtcaactata ttgggacccc caggatctgt ctatgaagga ggggtgttct ttcttgacat    480
taccttttca ccagactatc cgtttaaacc ccctaaggtt accttccgaa caagaatcta    540
tcactgtaat attaacagcc aaggtgtgat ctgtctggac atcttaaagg acaactggag    600
tccggcttta actatttcta aagttctcct ctccatctgc tcacttctta cagattgcaa    660
ccctgctgac cctctggtgg gcagcatcgc cacacagtac atgaccaaca gagcagagca    720
tgaccggatg gccagacagt ggaccaagcg gtacgccaca taggggcctg ctgcctgccg    780
ccccgcggga cctgtgcaag cacattcacc aagtgcatcg gtagccctgc ccacccctcc    840
agacctcggt tcttattttc ctatttttat taaatttgga accattttgt gatggtatgt    900
tgtccatctt cccatcccag ttcttcctgc cccccttcct ctctcccacg ctctctttta    960
tctctcantt ttatyccckt ggttgatttc tgttawcttg aaagatkkgg gattttyycc   1020
cacctcatca tagatgggaa cttktgtttw cagwrcaaac aatgttgggc tgtnaatagt   1080
aagagctttc ttacaaagct ktgtattrct gtgtggttkg gtctcggtgt cgctgtcatg   1140
tggattggat tcctctctct ttgtgtactc tgggaaaaaa tca                     1183

<210> 1232
<211> 1937
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1884)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1893)
<223> n equals a,t,g, or c

<400> 1232
aagaggagct gggcaggagg cagggcaagg agaaagctgt tcgggggtct tgtctggatt     60
ttggttgcct cctccaatgt tcctctacct ctactacaag gatgggtcat gtttgtgtcc    120
gtgacagcgt ttttcttttc gctcctcttt ctgggcatgt tcctctctgg catggtggct    180
caaattgatg ctaactggaa cttcctggat tttgcctacc attttacagt atttgtcttc    240
tattttggag cctttttatt ggaagcagca gccacatccc tgcatgattt gcattgcaat    300
acaaccataa ccgggcagcc actcctgagt gataaccagt ataacataaa cgtagcagcc    360
tcaatttttg cctttatgac gacagcttgt tatggttgca gtttgggtct ggctttacga    420
agatggcgac cgtaacactc cttagaaact ggcagtcgta tgttagtttc acttgtctac    480
tttatatgtc tgatcaattt ggataccatt ttgtccagat gcaaaaacat tccaaaagta    540
atgtgtttag tagagagaga ctctaagctc aagttctggt ttatttcatg gatggaatgt    600
taattttatt atgatattaa agaaatggcc ttttatttta catctctccc ctttttccct    660
ttcccccttt attttcctcc ttttctttct gaaagtttcc ttttatgtcc ataaaataca    720
aatatattgt tcataaaaaa ttagtatccc ttttgtttgg ttgctgagtc acctgaacct    780
taattttaat tggtaattac agcccctaaa aaaaacacat ttcaaatagg cttcccacta    840
aactctatat tttagtgtaa accaggaatt ggcacacttt ttttagaatg ggccagatgg    900
taaatattta tgcttcacgg tccatacagt ctctgtcaca actattcagt tctgctagta    960
tagcgtgaaa gcagctatac acaatacaga aatgaatgag tgtggttatg ttctaataaa   1020
acttatttat aaaaacaagg ggaggctggg tttagcctgt gggccatagt ttgtcaacca   1080
ctggtgtaaa accttagtta tatatgatct gcattttctt gaactgatca ttgaaaactt   1140
ataaacctaa cagaaaagcc acataatatt tagtgtcatt atgcaataat cacattgcct   1200
ttgtgttaat agtcaaatac ttacctttgg agaatactta cctttggagg aatgtataaa   1260
atttctcagg cagagtcctg gatataggaa aaagtaattt atgaagtaaa cttcagttgc   1320
ttaatcaaac taatgatagt ctaacaactg agcaagatcc tcatctgaga gtgcttaaaa   1380
tgggatcccc agagaccatt aaccaatact ggaactggta tctagctact gatgtcttac   1440
tttgagttta tttatgcttc agaatacagt tgtttgccct gtgcatgaat atacccatat   1500
ttgtgtgtgg atatgtgaag cttttccaaa tagagctctc agaagaatta agtttttact   1560
tctaattatt ttgcattact ttgagttaaa tttgaataga gtattaaata taaagttgta   1620
gattcttatg tgtttttgta ttagcccaga catctgtaat gtttttgcac tggtgacaga   1680
caaaatctgt tttaaaatca tatccagcac aaaaactatt tctggctgaa tagcacagaa   1740
aagtatttta acctacctgt agagatcctc gtcatggaaa ggtgccaaac tgttttgaat   1800
ggaaggacaa gtaagagtga ggccacagtt cccaccacac gaggggcttt tgtatkgttc   1860
tactttttca gcccttttac tttnctgggc tgnaggcttc ccctgggagt ggcctgtatt   1920
aagttggggc tatttag                                                  1937

<210> 1233
<211> 857
<212> DNA
<213> Homo sapiens

<400> 1233
atccggcccc ggtccccgtc cccttccctc ccccctgccc taagccacct ccacctctgt     60
cctggccgcc tcagggcgcc ctgaaaggac caggacatgc ggctgcgctt ttggctcctc    120
atttggctcc tgctgggatt tatcagccat cagcccaccc ctgttatcaa tactctggct    180
gaccatcgtc atcgtgagac tgactttggt ggaagtcctt ggataattat cattattgtg    240
tttctgggac gttacaaatt taccattctc ttctgcacaa tttacctttg tgtgcctttc    300
ctgaagacta tcttctggtc tcgaaatgga catgatagat ccagggatgt acagcagaga    360
gctaggaggt ccaaccgctg tagacaggaa ggaattaaaa ttggcctgga agacatctgt    420
actttatgga aacaggcgga aacaaaagtt caagctaaaa tccgtaagat gaaggtcaca    480
aagaaagtca accatcatta caaaatcaat ggaaagagga agaccgccaa agaacagaaa    540
atgtttcaac gtgcgcaaga gttgcggygg cgggcagagg actacyacar atgcaaaatc    600
accccttctg caagaaagcc tctttgcaac ygggtcagaa tggcggcagy ggagcatcgt    660
cattcttcag gattgcccta ctggccctac ctcacagctg aaactttaaa aaacaggatg    720
ggccaccagc cacctcctcc aactcaacaa cattctataa ttgataactc cctgagcctc    780
aagacacctt ccgagtgtgt gctctatccc cttgccaccc tcagcggrtg ataatcttca    840
agacacctcc cgagtgt                                                   857

<210> 1234
<211> 1788
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<400> 1234
ttttnttttt tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt     60
tttttaaagg tgctacacaa gagatattta ttaatgttct gttgtattta cagttttaac    120
atagcaaacc aagatgaatt accacttggg cagaaagcac atcattctac attataaccc    180
actggtttct gctaacacat tgtaaaagca agtagtacag tatgttaggg atcatctcaa    240
aagttccaag ctacttcttt ctttgctcct aagtacctaa tcctctcctt actcccagac    300
tttggcctaa tcaccaggag acaaaaggaa aataaggggg gtgggggtgg gggtgggggt    360
gaagaacgct aattatagaa agagtgtcaa gaattacatt ttagtaatta agcttcattt    420
gtatcctagt gctttctgtt ttatacagtg acaacacctt tagaatccct taggtacaat    480
aaggtaccgc agaattgtga atacaggcta taaaaaatta atgcttatta tttaccaatt    540
aaagacttat ttttgaccac accttaaatg tatttttgca ctatgatttt gcttccaggt    600
gttcatacag aattgaataa atttctagat taacttgaac agcaaatatg gattatgtgc    660
aaaaacacag tcataacaaa agtttaactt ttgagaaaac ccctttaaaa tggccagcat    720
tatacatatc ttacaatatt taattccaag ttcattttga gatggaggat gaataaagca    780
agactgcccc ctaccgacta cagggacatg gctcatgcta cttaaaatga ctacaaacaa    840
tatataaggc attattaata catcacagac ttgattgcaa gagctttttc aaacattaac    900
cactaatgat tcaatgatta cagaattctg cattaactat taaaatttta cacctaggaa    960
caaatagaga gaaatgatct tttcaacagt actttatttt tttaaagcag gtgattattc   1020
ctctgtgttc tgcatcttga ttcacttcct gcaggtgttc tcttgcttct tgagagagaa   1080
ttcataaatg cagggaaata ggtggaaaac ctgacaatca ggatccattt aattagagag   1140
agaccaaatc ctgaaatggc cccatacctt cctgcagctg aagtggtcag gcaaaaagac   1200
aggaaaaacc caatccagtt aaagaggaat gccatgaaaa aagttaacat gaaaatccca   1260
tcatttccta tcctcagctg gtcagcatca tcaaaatcat cccgacccac aaaatcctca   1320
tctctcccag gaaccaaagg gatagtagct tcagccttgg tcctctccgc ttcatcataa   1380
ctgggcagtg ttgtagctac attgtaagat gggggctttg gaaacccaga ctcatccttg   1440
tagtcaaaat atgctgcgct ctctgcagaa atgctgctgt aaggtggagg agcatcacct   1500
gcagcctgtt caggttctcc agactcttct tcattctgca actgctggta ccggctgccg   1560
caggccggct cgaccgccgc cagcgccgcc aacgccaacg ccatggcgca gccggcagca   1620
gggaagcaga gcgagcgagc gagctagctg aaggggcgcg gccgctgcgg cttgggagcg   1680
ctgggaggcc gagggggacg cgccttgggt gggtctcgat ggccgccgcc gctcccgggc   1740
gagacgctct tctcaggctg taagcaccgc cgccgccgcc gaggatcc                1788

<210> 1235
<211> 2387
<212> DNA
<213> Homo sapiens

<400> 1235
agttgtattc atgtgttctg agttctgcat taatccagat cttatgcttt ttaaagacat     60
ggctggtgtc ttctttgttc gtcaaggcaa tgtatggaat gatggaagga acacaggatt    120
tattgtcagg cattgctgag ttttaaacac agctctacct cttactagct ttgtgaattt    180
gggcacctta ttgaacttca atgagctcat ctagagtcat gcattctatg gctgtcacaa    240
agatgggtcc tttctgtttc ttctgtgtct gctacagaac ccaatatggc atgatacagg    300
taacagttgc tcaagttaga catttaaagg gaatgatatt tgtgatgata gcaatcttgc    360
tacttgttcc atccatcatt ttgtactcta tactgttagg caatagggaa gggctgaggc    420
tctacctctg ggagtcagca aacttcccga aaagggcaag agaataaaac acttggactc    480
tggaggccag acagcctctg gtgcacctac ttaattctag cattgtagta tgaaaacagc    540
cacagaaata cgtagaggac tgggaatgat tgtgtcctaa taaaactttt ttcaaaatag    600
gcaggagact aggtttggcc tatgggccaa agtttgccaa cccgtaatga tataatggtt    660
cttgcagaaa ttattttggc tttctgacag catgactcta agtgtggtct gtggacagta    720
cacagacttt ttattagcag tctgcaatga gacaaggagc ttcmccagaa gaaaccaact    780
acattattca gcagattgtt tacttcagct gacattttgt tgtgtttgtt ttcgaagcaa    840
gacttcgcca atgaaagaar taattgattt atattctggt acaagcacct tatctatcac    900
agaccagtag caaacagcac aaaagcactt tgagtggcac tgttctaatc attcaccagg    960
aaacacagac tgtattcttt atgatcacca aaaacaagaa tgaaagctca aaacccaatt   1020
ttsccttctc accattctcc ttcttctccc aggatgtgcc cctgattagc ctggccaaca   1080
tcttgcacaa tgccaagctc tggaatgacg ccgtcatagt agccaccatg gcagtagaga   1140
tcgcaccaca ctttgctgtg aaccacttca ctctgggcaa tgtctacgtg gcaatggaag   1200
aatttgaaaa agcactggtg tggtatgaat ccacattgaa gcttcagccc gagtttgtcc   1260
cagccaagaa ccgaatccag accatccagt gtcacttaat gctgaagaag ggacggcgct   1320
ctccttagtg cacttcttcc ttctctcttt ctctttactc atgctctaaa aaaaaagaat   1380
aagaaaagaa accaatcatt gtcagtatct actattaatg atgtgtgtga aaataactaa   1440
gacttataac aggactttta catatgtggg aattggtttg tttttgtttt tacgtttctc   1500
ctttccccca accaacctca gaagaggcac cttcagaaac acacatttct taaaaggaaa   1560
gtgcagcttc aagatattgt gtaaatactg agccaagaca tttctggagc tgtgctctgt   1620
ctccaaaaac ctcaatgcct ttagggcttt tctcagtggt ccagctagcc ttctctttgg   1680
aggaggatga agccgcattg cacattctct gcttcctgtc gtagcctctg ttgtcaatgg   1740
aaatgcggaa gcccatctgg tgcccgtcag tgagaagcaa cgttctgcgc tctctccgtt   1800
agacctccat gctgtcccca gtcttgtcca ttccatgctg ctgtgttaca aactctcaga   1860
ggtagtttgc aggggaggaa ggggaatatg attttaaaaa caaaatattt acaacaacaa   1920
aaattcttag gatcacctga cctttgtaat gttatttatg ttggggaggg aggggggctg   1980
agaaggggaa atcagcagtg tgcaacatct ttataatttg tactttaatt acaaatcaca   2040
aggaaaccaa taagttgaaa tcctatataa caggtttata tatatagaat atgtatattt   2100
gaagccctct acagactgag tctatgtttt actaattctt tgttcactgt gttacccatc   2160
ttggaataag ttgtgaatgt cagctccctc tctctgaggc ctccagactt agctcctcag   2220
gagggtaatg agccaaggtt gagtgtttcc atacaatgct tttacctttg atcccaggag   2280
aatcagaaac tccaacattt tggaatcttc aagggcacat actgagaaaa aaaataaaat   2340
tgtttatgag caaaaaaaaa aaaaaaaaaa gatctttaat taagcgg                 2387

<210> 1236
<211> 2166
<212> DNA
<213> Homo sapiens

<400> 1236
cctcgagttt tttttttttt tttttttttt tttttttttt tttttttttc tggctacaaa     60
ttttattccg ttacaaatag caccgagccc ttggggctgc ccctgtggag agggatcccc    120
ctcctggacc cccacctcct cccctgagct acccakgtag tgtctgggag ctggcacacg    180
gcccagggtc cctctggaag ctgggccagg ccaaggggtt aggcccaggc ccttcgtggg    240
gtgggcccag ggccagctgt ggcagatgtg caggtaggtg agcggcagcc tctcagatga    300
gcacactggc cacgggcacg cgggtggagc ggccccgctg gggcaccaca atccggtcgt    360
ctgtggaccc tgcttcgtgc agcaggccct gcacgtgcag ctgtgcccgc cggcggtcgg    420
cctcaatgaa gatggcggtg cccaggaarg ctgcgccgcc cagtgcccca acaaacgcgc    480
agagcatgag cgagaactgc agagcccgga actcggacaa gaaggagggg ggccagttcc    540
ggcgcaggcg gtcagagatc aggccaatga ggtaggggct cccagcatca cccagcaggt    600
gggacagcac gatctggaag gcctcggcgg tggagcgtcg ggtagggatc accacgtaca    660
gcagaatgtc ggccacgatg gcccagttca tggacaggag ggtctctcca atgaagatga    720
aaatataagt ggccacgatg ctaccacggg cgcaggcaag ggacaggaag aggaagggtg    780
cagagcccag gaggccagtg gcacagacca ggggatcagc ccgggggttg gagtggcgga    840
gccggcggct gatctccaca cccaggccca cacccaggac tccggtcagg caggtgatga    900
gtccaaagat gagactgtca gaggaagagc aggagtctcc gggaaggcag ggtggggtct    960
ccccaaggac cacgcgggaa cgcagcagga atgccggagc ccacagagcc agggagcccg   1020
tgacaaaggc cacagcagtg aagcccaggg aagacaggac gaaactagga tttcttgcca   1080
gagccctcag atctgcccac cacgaggtgg ggttcagggg tggcaaatct gagtggcgct   1140
ccacggctcc ccttggcggc tcccgcacta ccaggaacag cagcagaacg gccaccactc   1200
ctagacccgg tgtcaccctc agagcccagt gccagtctcc agccatatcc ttcactttgg   1260
agcctgcaat gtagcccaga ccactgccca ccggaatggc aaagtagaag atgctgagca   1320
tccggctccg ctggtcggcc acaaagaggt cggcaatgag agtgggcgcg atggtggaat   1380
aactggcctc cccgaccccc accaggcccc gggtcaggag gagcagccag aaatgctctc   1440
cggggatgaa ggatgacccc agtgtcacca gggaccagaa ggcaatgccc ccgcacatga   1500
gatacttccg attgtacctg tcacccaggt agccaaacac aggtgccaac accatgtaac   1560
tggagatgaa cacggtctgg atgagcccag agctactgtc cccgatgttg aagaactgct   1620
cgatgtcggg aaggacgcca gccacggtga agcggtccat gtagttcagg agattgatgt   1680
agcacagcac cgccactatg agagccgaac ggccgggaga caggccgktg atgcgctgca   1740
gcccctcctg gtycgggacc tcgggctcct cggacttcgg gttccccgtg gaccytggca   1800
accccggggt gccaggcact ggcccgtcgt ccgggtcatc cgcctgcgag gggaggaggc   1860
tggagaaagg aggatggacc gaacacaggc gagggaagtg cgcccggaga cggggagctt   1920
gccctgaagc acagagcacc actgagaagg gacccgggcc ctgtcacgcc tccccgtctc   1980
agtagacaca cagcgcggag gggacgtgcg gaatacacgt gatgtcgggg acaggagcgg   2040
gctgaagagg gcacgatccc acgcggaggc cacccctcac ccggggtagg agcccgctgc   2100
acttgctgtc gctcagcccg ggcgctgcac cacggcagcc gccatgttgc cggacgcgtg   2160
ggtcga                                                              2166

<210> 1237
<211> 2189
<212> DNA
<213> Homo sapiens

<400> 1237
cccccgggct gcaggaatgt ttctgggcaa aaccatgacc cggaacagat tgatttgatt     60
gatttactag tgcagttgtg gcgtggcaag atgacaatca tcatttccgt cattgtggct    120
attgccctgg ctattggata tttggcagta gcgaaggaga aatggacgtc aacagcaatt    180
atcactcagc ccgacgtggg gcaaattgct ggctataaca atgccatgaa tgttatctat    240
ggtcaggctg caccgaaagt atcggatttg caggagacgt taattggtcg cttcagttct    300
gccttctctg cattagcaga aacgctggat aatcaggaag aacgagaaaa acttaccatc    360
gaaccttctg ttaagaacca gcaattacca ttgactgttt cttatgttgg gcaaactgca    420
gagggcgcac aaatgaagtt ggcccaatac attcagcaag ttgacgataa agtgaatcaa    480
gagctagaaa aggatctcaa agacaacatt gctctgggac ggaaaaactt gcaggactct    540
ttaagaacgc aggaagtagt cgcgcaggag cagaaagatc tgcgtatccg tcagattcag    600
gaagcgttgc agtatgcgaa tcaggcgcag gtgacaaaac cgcagattca acagactggc    660
gaagatatca cacaagatac gttgttcctt ttggggagcg aagcgctgga gtcgatgatt    720
aagcatgagg cgacccgtcc gttggtgttc tcgccaaact actatcagac tcgtcaaaac    780
ctgctggata tcgaaagctt aaaagttgat gatcttgata ttcatgctta ccgttatgtg    840
atgaaaccga tgttacctat tcgtcgtgat agcccgaaaa aggcaattac cttgattctg    900
gcggtgctgc tgggtggcat ggttggcgcg gggattgtgc tggggcgtaa tgctctacgc    960
aattacaacg cgaagtaatc ttttcggttt taaagaaaaa gggcagggtg gtgacacctt   1020
gcccgttttt ttgccggatg cggcaacaat atcgcatccg cttaccccgc aactcactga   1080
tgccgtttac gcaggttctc aattaccgtc gttaaatcca gcccctgatc ctgcaacaac   1140
accagcaggt gatacatcaa atcagacgcc tcgttggtca gctcaaagcg gtcatgtacc   1200
gttgctgcca gcgcggtttc cacgccttct tcacccactt tctgcgcaat gcgtttggtg   1260
ccgctggcag cggccgcaac tagccggtta cgcatgggca gcatgatgag caacgtgatt   1320
gcggtctgtg accgcgaagc cgatattcat gcttatctgc aggacaaact ggcgcataac   1380
gagcgcttcg tggtgcgctc caagcaccca cgcaaggacg tagagtctgg gttgtatctg   1440
tacgaccatc tgaagaacca accggagttg ggtggctatc agatcagcat tccgcaaaag   1500
gcgtggtgga taaacgcggt aaacgtaaaa atcgaccagc ccgcaaggcg agcttgagcc   1560
tgccagtggg cgcatcacgc taaaacaggg gaatatcacg ctcaacgcgg tgctggccga   1620
ggagattaac ccgcccaagg gtgagacccc gttgaaatgg ttgttgctga ccagcgaacc   1680
ggtcgagtcg ctagcccaag ccttgcgcgt catcgacatt tatacccatc gctggcggat   1740
cgaggagttc cataaggcat ggaaaaccgg agcaggagcc gagaggcaac gcatggagga   1800
gccggataat ctggagcgga tggtctcgat cctctcgttt gttgcggtca ggctgttaca   1860
gctcagagaa agcttcacgc tgccgcaagc actcagggcg caagggctgc taaaggaagc   1920
ggaacacgta gaaagccagt ccgcagaaac ggtgctgacc ccggatgaat gtcagctact   1980
gggctatctg gacaagggaa aacgcaagcg caaagagaaa gcaggtagct tgcagtgggc   2040
ttacatggcg atagctagac tgggcggttt tatggacagc aagcgaaccg gaattgccag   2100
ctggggcgcc ctctgggaag gttgggaagc cctgcaaagt aaactggatg gctttcttgc   2160
cgccaaggat ctgatggcgc agggggccc                                     2189

<210> 1238
<211> 1164
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1151)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1163)
<223> n equals a,t,g, or c

<400> 1238
gggatgcagg acgctcccct gagctgcctg tcaccgacta rgtggagcag tgtttcttcc     60
gcagactcaa ctgagaagtc agcctctgsg gcaggcacca ggaatctgcc ttttcagttc    120
tgtctccggc aggctttgag gatgaaggct gcgggcattc tgaccctcat tggctgcctg    180
gtcacaggcg ccgagtccaa aatctacact cgttgcaaac tggcaaaaat attctcgagg    240
gctggcctgg acaattactg gggcttcagc cttggaaact ggatctgcat ggcgtattat    300
gagagcggct acaacaccac agcccagacg gtcctggatg acggcagcat cgactacggc    360
atcttccaga tcaacagctt cgcgtggtgc agacgcggaa agctgaagga gaacaaccac    420
tgccacgtcg cctgctcagc cttggtcact gatgacctca cagatgcgat tatctgtgcc    480
argaaaattg ttaaagagac acaaggaatg aactattggc aaggctggaa gaaacaytgt    540
gagggsagag acctgtccga stggaaaaaa grctgtgagg tttcctaaac tggaactgga    600
cccaggatgc tttgcagcaa cgccctaggr tttgcagtga atgtccaaat gcctgtgtca    660
tcttgtcccg tttcctccca atattccttc tcaaacttgg agagggaaaa ttaagctata    720
cttttaagaa aataaatatt tccatttaaa aaaaaaaatt taaaaaaact tttggggggg    780
gccggtaccc aattcgccct atagtgagtc gtattacaat tcactggccg tcgttttaca    840
acgtcgtgac tgggaaaacc ctggcgttac ccaacttaat cgccttgcag cacatccccc    900
tttcgccagc tggcgtaata gcgaagaggc ccgcaccgat cgcccttccc aacagttgcg    960
cagcctgaat ggcgaatggc aaattgtaag cgttaatatt ttgttaaaat tcgcgttaaa   1020
tttttgttaa atcagctcat tttttaacca ataggccgaa atcggcaaaa tcccttataa   1080
atcaaaagaa tagaccgaga tagggttgag tgttgttcca gtttggaaca agagtccact   1140
attaaagaac ntggactcca acnt                                          1164

<210> 1239
<211> 1724
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (314)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1076)
<223> n equals a,t,g, or c

<400> 1239
gcggccgccc tttttttttt tttttttttt tttttttttt tttttttttt ttttttgaga     60
tggaatcttg ctctgtcacc taggctggag ggcagtggca caatctcggc ttactgcaac    120
ttccgcctcc tgttttcaag ccattctcct rcctcagcct cctaagtagc tgggattaca    180
ggcgcgcacc accatgccca gccaattttt gtatttttag tagagacagg gtttctctat    240
gttggtcagg ctggtctcga attcctgacc tgctgattcg cccacctcag cctcccaaag    300
tgttaggatt acangcgtga gccaccgtgc cgggccaagg gcaatyctta aaagcacagc    360
tttttagact ccacaccaac cagaatgtga tccaacagat ttgagattag ggtctcagct    420
ccccgggtga ctgtacacag ccacatttag ggactgatga cctagagaac tgggctgtga    480
aatgattgag atatctgtgg ctaaagacac ctcaagacct ctctagggct catgagatct    540
tggtaggcct gttaccctca ctgccagtcc tctctgatcc aggaatgaaa agctttctaa    600
agccaacatt taggaaagac actgccaatt tcacaatatt ttaatatttt tctgagagct    660
gacttgggga gggattgctg aatwcaagtc cagatgaaaa gtaaaggctg caaaatwacc    720
acccatttcc ataccccact tccagytcca tataccctgc cacctgtctc aaggagggcc    780
cagtcttcct acttgtagct tggcagtcac agaccacaaa caggagccac tctatcccca    840
cagattactt ttatgaccca atcatgaccc aagcttcagg agctcctagg cccttggctg    900
gcttcctgca atgctcccag cctccaccaa aggaaaccag ccctgaggga caggctgact    960
catgtccact tggccaagcc agcctggccc aaaaagccca gaaagaaatc tactsccatc   1020
tcttgcactc actgacacat gctagcatgt acatagaaac agccgagcag tgaagntaac   1080
agagtcgcca tgttctcctc agggaatcca gaggaactgt tggtggtacc ccccttccca   1140
ccacttaccc tggcacagtt taacaaggcc catgacaatg atggcaatga gcgctacgac   1200
cttggcgtaa gtgaacgtgt cctgcacacg tgtgccccac ttgacatagg cacagttcac   1260
aaatgtcagc agacatatgc aagcagcagc caggagacgg caggccaggt atgggggatc   1320
acagctgggg aaggacggct ggatgatgta gttggcaaag gtgatggcga tgatggcctg   1380
accggtgggc tcaacaacta gcagtgagac ccacaggcgg atgaaggcaa tgaagccccc   1440
aaaggcctct agaatataag cgtagctggc tcccgacttg gtgatggtgg tccccagctc   1500
tgcataacaa agggcaccca caacagagaa gagcccacca atggcccaca caatcagtga   1560
catcccatag gaggcagtgt gtaccagcac acccttgggt gagacaaaga tccctgagcc   1620
gatcatgttg cccaccacca ggctgacccc attcagcagg gagatctcct tcttcagctg   1680
catagtttcg gaggaccttt gaggtggcga gctgacatct tctc                    1724

<210> 1240
<211> 1189
<212> DNA
<213> Homo sapiens

<400> 1240
gcggccgccc tttttttttt tttttttaca gtgagagaaa aatggaattc cgttttattt     60
tgtcctctct gaaacttcca tttacaccat ggcctcatct atcaagaaga ggaagaaaag    120
gctctgcctt ataccataaa aatcaagtac tcatgtactt gttagaggtg gcaggatatt    180
tgtttctcca gttttttggc tctaagaaat tacactttca gtaccagtgt agtgaggaac    240
cactggcaaa ctgttggaaa tgtcttctgg attagtcagt gtaccatttc ataaagtgct    300
tctggagtta aaatctgcca agctgtcaaa agtgtccaca cttttgcaac aaaggataaa    360
agatcccagt gggtatcacc gagtccttcc cagctgggtc tcattattgg cactgctgct    420
ttaacctcca agccgctggc cctcacccca ggcgaagcct cctggccgtt cctcaggtag    480
tggattgtaa tttggatcct catctggtgt atcaaaaata gctttcaaaa tagatggtgt    540
tttcagaatt cttattccac caggttgatt gggaaataca tcttccaaga aaaaatatat    600
gtgtccaact gcaataccca aaaggtccac aatgattgag ttccccaaca acaaggaaaa    660
tcccatgagc acccagggca gaaagggggc ctggaagttg agaaggccga agaagttcat    720
gcggacatag gggttccttc ggctccacac atagacgagc attattgtaa aggcctggcc    780
caagaaaact aagctcacaa acagaccaaa aagggtcatt aagaatccac caaaaaggaa    840
cataaataca aagtctgctg tccgacctcg gaaagagcct tcttctagca ttcgacagta    900
acgatataga aaaatcatgt taaataaaaa attgaatcca actggcccaa aaaataagaa    960
gttggtgatt aatctccata tttgaaagtg tttaaagatt aattcaggat tgaagtacaa   1020
ctgaaaaggt gtgatcaatt ccaactgcac ggcggcggtg gtgaggacgc aggcagtggt   1080
gtaggcgcgg ctgaccggtg ggatctgcag gtactccagc cgcaagctct ggtacgccat   1140
ctytgtgccg aattctgcag cccggggatc cactagttct agagcggcg               1189

<210> 1241
<211> 1129
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (213)
<223> n equals a,t,g, or c

<400> 1241
gcggccgccc tttttttttt tttttttttt tttttttttt tttttttttt tttttactgt     60
taggcagctg ccctagggat gactgctcct ttatttgttg ttaatgaatc ttgacctcct    120
tgtgtgaccc tggttgttac tccattctaa gattggcgtt tttttttgtt tttttttttg    180
taaatagaga caaggtctcg ctatgttgcc cancctgggc tcgagcagtg ctcctgcctc    240
accctcccaa agtgytggga ttwcaacagg tgtgaaccma cacacctggy tccccaaggt    300
tcagttttta tcctcctctt ggagaggtga gtgacttgag gtcatttctt cacaagctcc    360
ggtaggcacc cacagtattg tcaaagagtt ttgtgttagg gaagtgtcca gttttgtcca    420
agaggaaata gaagcgtcgg cctttgactt tcagaggtag catggcaggg acttcacccc    480
ggtgggccat gcaagatacc tgcttcaaag gaactgtgaa atgggccccc aagccaaagg    540
gggcatgagt ggtgagggtc acctgctgcc ctccagctcg aagcaccact gagcgcacag    600
accggagaga gaagagaaga ccagcaccga gtacgagggc tccgatggcg ccgcagccga    660
cggccagacc gtagcgccag arcgcggagc gcaggtcgaa ggggccacga tttgggacct    720
ccgcatccag aggctgcacc ggaaccgggg gccgggacac ggctgccaca gccatggaag    780
cccagaagac gccctggccc gcgcagaaca gcccgaggat ggtgaagaag cggccccgat    840
catgctcaaa gagcagcaca tcccgttgca gcgtcgtgcc ttgcaggggc cggcaggtga    900
gcaggggccg cagcacggct agcagccccg tgggccatcg cctccaaggc gccgccatgg    960
ccagccgact tccggggtgg gcttcctgcc gcagagccgc cttctccctc cctgggcgcc   1020
cccgctagag gcccgccccc cttgctcagg gctgggagga gacaaccaat ccagcacgca   1080
gaacacgaaa tacaacatca ctctttatat taaaaagtgc agaacacga               1129

<210> 1242
<211> 1339
<212> DNA
<213> Homo sapiens

<400> 1242
gcggccgccc tttttttttt tttttttttt tttttttttt ttcaatgaag gaaaagactt     60
tacttcccta gaggaaaagg acaggccatg gttttatagg acccaaattc ttctttcccc    120
taagctgctg gtgctggcgg tcactgatgg gagagggagg gctggcgcct ccctgtgcta    180
ggctgggagc cctttgggag agtgtggagc tcctggagac atcaactgac agggctctgg    240
ccaggagtcc ttgggaggcc ccgtcaccca agaacccctc accctagagc aggcctcccc    300
agccttggcc cccactcact tcatggggga cttccacgcc caagtcagct tccatcagga    360
agatcctggc gatcttctca catggcccat gcaggattct ggaaatcagc gggtactcgc    420
agtcttttaa ttttgtccgc tccccagact cgtgaacgat gtagagtgcg aactcactgg    480
ggccatcttc caccctaaat ttgttcagca gcagggtgag cacctgcagg gttgtcatgg    540
tgctgttgac cctcacattg gtcacggatc cataggctgg agtaaacacg gaggtcttat    600
gattgtagaa gtggccgttg atagagaacc ggtgtcgccg gatgcgctgg gcctcaccgg    660
gggcgcggca cttgggcctc ctctggctca tgcaactggc gtcgctcttg gtccgcatca    720
gctggggggc ctcctctgcc tcctccaggg gccccgagct gtctgtggaa ctctcagcct    780
tgtgcactgg ctgaatgctt ggcccctggg ctgtgatgtt cccgttctgg ggcgatggct    840
cctttctgaa aacagacaac tgcagggctg agatggctgc cggcagagaa agggagctca    900
ggccaaggag aagagaccag cagcccagag ggcagctagg ccgtctgggc atccatgagg    960
tggaggggag gtgcacctgc tcccggtcat cctgcatctg cagccggatg ggccgcctca   1020
gcccccaggc aatgttgagg agcccctcga tgatcagagt cccttcttcc tcacggtgtc   1080
tcagctggaa gctcttgccc tcatggtagc agttgtaggt tttcagcagg cctaagagct   1140
ccgacttctg aatggacttg ctgtcactga tgggcacgtg agaactcggc agacagtctt   1200
ccttcatctt ctcttcctct tgtctgcaga cctagaagtt acttgcgtcc agtcatcgcg   1260
cagtccagaa gccactgcat gtgtcgtgtc ctcgcttgca ccggagtgcg cccgcagcgc   1320
ctgctgaccc caggcttca                                                1339

<210> 1243
<211> 2021
<212> DNA
<213> Homo sapiens

<400> 1243
tacgagtttt tttttttttt tttttttttt tttttttttt tttttttttt ttttttttag     60
aatacctggt ttattgggaa aacttcataa tgaaaactac aattagcttt ttccacaact    120
tacaaaataa taatctgata tttaaaatga attggttttc attatgtaag tcgaaatggt    180
aaaaaatcat aatgacctat ccgatgcatc atatatatgc tattcagaga aactcaaatc    240
cccgaattct cctgtggcat gttttatatc agacatttaa aatctgttta ccaagaaaga    300
ccaggatttt aactatatgt aggtttctgc ttacagttgc aaactatcag aagcctgtct    360
atatgataga gcccagataa acctgagatt tagaaaagca agtcatttat tctcctgagg    420
ctgttttagt ggcacttttg tgacaagaat gaccctccta atgctttact acacaactta    480
accagatcta tcagtcatga taaattagac ccagtccatc tttcaatcca gtctactctg    540
gttctgaaca tataaacaca aaacactaca gatttattaa tatagcattt tcccacaccc    600
taaccctata aagaacttta aaagagaaaa tttcatctaa atatttcaca cttaaaggaa    660
agccttacca actatggcaa caggtttgga ccatgaaata gtactttcct agatgacata    720
tcgagtcaac atgaagcctt agctgaaatg aatgattcag gatattaatg agaaattctc    780
acaaatgata tgcatttagg aaatgatttt gctttcctta aatagttcga aggcttgaaa    840
ataaactttt tttttgcatt tcttttagaa tgtttggtca ttaacaactt ttaaccttat    900
cttcctcttc tccttagccc ttaacagacc gagtccattc tatttggaaa taacaagaac    960
ttgatcagat tattaaatct tggaaacctc atttttacct tataaagtgt taagtttcac   1020
gtgcatattc tcttacaaat gtagtataaa tgttatggat agatataagg aaatattggc   1080
atagtatagg taattagtga aaagacacaa cttcacaaaa cataataaaa gataaacatg   1140
aaactataac actacttaaa aaatattttc tcccaaatta ttttagcatt tttgactagt   1200
ttaataatat gaacactgcc aaaaaatggg ttcaaagtcg cctggagaaa cagtttcttc   1260
ttctggagtc catctcagca gcagcgattt tctcccacat tcattcccaa gttaggcaga   1320
tgtgtagaag tacctgggct tggcattgcc cagaaggtca tcttcgtagt tggggaggca   1380
gcagaagaag aaggcacagc cratcaggat aatcgtggct gcccacccaa agccgtaggc   1440
ccagttatag atgtaagtga cagcasggtt ggcatgaagg gtgaaggtct gggtgtactt   1500
cacggggtaa attaccaggg agatgatctg gaacacagca gccaaggcaa ggagacctcc   1560
aatcactctc aggaagacaa gcatctgggg tccacagagg gcgaagaagg agaggatgaa   1620
acagatcacc aggatgatga agccacagaa gagcatggca gccgctgctc taccccacgc   1680
gtactccatg aggctctgac agccctcctc gtaggacccg ctgccgccgc cctcttggga   1740
gcatttccac cacagcgagg acgtctggcc gtggtcgcta gactgcaacc agccgcggcc   1800
ggccagcgcg atgatgtcga aggcgatggc gctgagtagg agcaggggca ggatccagcg   1860
gcagcgctcg caggccaggc cgcagcggat catgttgacg ggcggcgcgg ggccgagcgg   1920
agcggagcgg agcgggtcgg aggagcgcgc gggacgggcg acagcagaga gtggcctgcg   1980
agcgcgggcg ccgccacaaa agcgaagmgg mcgcggggag c                       2021

<210> 1244
<211> 2601
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2534)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2539)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2581)
<223> n equals a,t,g, or c

<400> 1244
ggggactcag tggagcagcg gggagttgtg tccaccttgc cgacgtcgct agccgtgggg     60
ctgtcctggg aaggcggacg gcgagcgccc ggtgtccgca ctcggccgcc tgccgtgccc    120
gtctgcgccc gtgtcatcct cactcgggac gcagggaccg tttttaaatc acaggggcgt    180
gtgtcagcct gccctaggac ttcatgtcta tatatttccc cattcactgc cccgactatc    240
tgagatcggc caagatgact gaggtgatga tgaacaccca gcccatggag gagatcggcc    300
tcagcccccg caaggatggc ctttcctacc agatcttccc agacccgtca gattttgacc    360
gctgctgcaa actgaaggac cgtctgccct ccatagtggt ggaacccaca gaaggggagg    420
tggagagcgg ggagctccgg tggccccctg aggagttcct ggtccaggag gatgagcarg    480
ataactgcga agagacagcg aaagaaaata aagagcagta gagtccctgt ggactcccat    540
gggtcatacc agccagcatc tgttcctgaa ctgtgttttt cccatcatga cggaagaaga    600
gagtgagccg caattgttct gaaaatgtca aacgaggctt ctgttttgca cctgcagatc    660
accgagttgg ttttcttttc ttttcttgcc tttttttttt tttgaaattt gccgagcagt    720
ggagccctct gacaatttgc aaggccctct gagaaaggaa gctgcttaga gccagggggt    780
tagtgggtga ggggagcgag tgctgttttt gagatcatta tctgaactca ggcagcctag    840
tagaggcagt ggtgggattc caatgggtct tggtgggtgg gaggtggggc atgtgcaaag    900
caagcaagga acatttgggg taagaaaaca aacatgaggc aaaagaaaaa atacatgttt    960
ttaagaaaac attgagcaga gaactgcagc caggatgcgc tcagcagaca ttcactctgg   1020
ctgctgggac atcagaaaac aaagtcttca tctctctctc cagtttcacc caccccaccc   1080
tttgctttca tttcaggtgt gttggtctat atgacaggga ggagagtaaa ggagagcagg   1140
agcaattggc tgcctgcaaa gccagctgga ggtgaagtgc aggaaaggaa aggtcacccc   1200
attctactcc atggcctctc tgctcccagc tgtggtaggc tcacatagcc agtgtgatcg   1260
gtttttaaga ggcagtgctt ttcagctttt ctccctgata tatccatttt gcttcccagc   1320
actttttagg agtagtgaga gcacttcctg cccttgttgg aagccccagg gtggacactc   1380
agcacgaagg tctctccctt aactgctgcc cttccaagac ttgctcccga gatggagtgg   1440
gcgtggtctt ccaggctggc ccttccttct cctcaccgcc accttccctg ccccagcccc   1500
agcagccatg ggtacatggg tccccagctc acctatggat tcccgccagt ctgcccagct   1560
gcagtactca cgccccatgg gggatcttgg tctgtttttc ttgtgggagc ctagtggaga   1620
gcagacgtgg ctttttatgt gtcttgttgg ggaggtgact tgcatggtgg ggacaaggct   1680
gtcgtggcaa ccttgggatc gagtttgaga ctaaaggatg tcatgagatc cctggcttct   1740
ccccatgttg ttcccggaca agggcagaag ggaggcatgg caagggacct ctgctgtcct   1800
tactcaacag tggtcctcat ccctccccac ctcccactgc ttcctgcaag ggcaccagtt   1860
gtatgagaaa gttggccttt ggacttagga tttcttattg tagctaagag ccatctgaag   1920
cagcaggttg caggacaaat gcttcagtcc gccgagagca gtaccgtgtg gccaagaggt   1980
ggactcagag ccttccttga gctaaactcg gccaaccaag gcacgcagca tgtcccctca   2040
ggtctccagt cagtccaggt tgaccctcag ttctggacgt gtgtatatag ctgtatttaa   2100
tacctcaagg tcattgtggc tctggggatg ccggggcagg aggacgaggg tgcgctgtgg   2160
acacagcagt ccgcggaatt ccgttctggg aagccaatgg tcgccggcac cccttgcttc   2220
ctccctctgt tgtctgcctg tgtgacacac atcaatggca ataacttctt ccaactcctc   2280
gcagaagtgg gagaggccgg cagcctgcac cgagaggggc tttctctcty ttgctycccg   2340
cttygttctg ttttggctgs araragkggk tcatccatac tctcattccc tygsctcccc   2400
ttgtggacgg gggtcttgcc ttttcaattc ctgtgttttg gtgtcttccc ttatctgcta   2460
acctgaatca ctgtcctggt cttgctgtgt gatgggaaca tgcttgtaaa ctgcgtaaca   2520
aatctacttt gtgnagtgnt gttatggggt ggttataatt tgctgggcct agacactttg   2580
nagaccgttg cagctgagaa g                                             2601

<210> 1245
<211> 2878
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2039)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2666)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2674)
<223> n equals a,t,g, or c

<400> 1245
tttttttttt tttttttttt tttttttcca tttcccctca ttttattaaa tgttccactt     60
atgtacattt taaagacgaa ccatttacaa gcttgtgcag tttgcctcct tggctcacag    120
gaggggaaca ttgtggaaag cctcaggata aacagaagac ttggtttttt gctccttttc    180
tctgtacggt acagtacgtt ttggtttaca accatgagta catacaatta aaaaaatccc    240
tcatgcaaat tgtagaaaaa attttctttc cttgaagctg gcagtgaaaa ataaagattc    300
atgtcatttt ctttgtgcac acccctgtgc gcttcttcct gtcagattct tccctaagta    360
ttaagagaaa taggggaaag ccacagagca cgctggattt caacaagtgg tcttgtcttt    420
ttaaagttca acacttcttg aacaattagc tcctggctgt aggaccagta atcccttaaa    480
caggcatgct ctccatctaa caggatgaag ttcagtaaag cagggactgc ccctgggggc    540
ttacaggatg aagactcaaa ctgggaatgg cttccaccct aaaactgttt gatcgcttca    600
gtatctcttg cttgctaata acacctgtat gatcctttgt ccagagggat ggatggtgtt    660
gagaatgggg aaaggggcca aggatcacaa gtgcaaaaaa tattgtttat gtcatgtttt    720
ggagggaagg tggtgaggaa aagacaaatc tattcattct ggataattaa aggtggtttc    780
atgcattttt aaagccacaa ttttatatct agggttgctg tagaaaccaa catctctgga    840
gagggaagga aagaaaagga gaaggaagag agagttcagt gggacttttt ttccattttc    900
atttttatat aaaagtgtta agaccacaat gaaaaaagtt ttttatccat atatataata    960
aaccagtttg tgagctacat aatttgtctt tcccatcttc agaaatgttc tcacattaac   1020
aatgattaga tagcatcatg cccaaagaca ttggccacac aataaaacaa acaaaaaaac   1080
ccagtactat gatacaattg aggtaaaagg ggaaacaaaa aaatttaaca tttgcccaca   1140
aataattttt tttctttttc ttaattttgt cagaaaaata ccaaacacag tgatttaaat   1200
ttaaaaaaaa aaaaagtcac aaaaacctgt ttttagcaga agtgaatgac caatgggcca   1260
gctccttggc tcagacgtga ttactattgg ttttcctaat taatccacaa atccacaggg   1320
aagtgtaagt caacttcagg ggggagtggt ggtataaaat taaaaaatag aaaccaaata   1380
ccccacctgg tatgccccct tttccctaag cccctttacc ctccctcaca tgttcccacc   1440
cccactccac accccctcat gaccccaaca ctcaaatctc catcagatct aggtcagctt   1500
cttcaaagcc atagaaagac tcggtctcac tttcaccctc aaagagctgg tgaagacttt   1560
caggctcaat tgtctcttca ggagatgatc tgggtcgtgg agtggaagac tcagaatgtt   1620
ccccactcag cttcagttgc tcctctaggg aggcaattag ctcctcctgc atgtcagcat   1680
ttcttgtagg tgagttaatg ttgccatcgg ggccaggcag aacactagcc accaggaagg   1740
agcgctgaac tagctctgga cagtccccaa tgacacctag cacttcaccc agccagacaa   1800
gcaccagctg aagcaggaca tcagaatcac atgcagtatc tgccatttcc cgagcctgtt   1860
ccttccattt tttatgcagg aagttcttga cagttctttt gatgcataca tctaatggct   1920
gaattttgga gctacagcct gctgggacca ctgcaggcaa agtgctagag gcactaagca   1980
tagccagtac ctcttctgac aagtgagtgc gatgacagtc catcacaagc atgcctttnt   2040
gcgctggcaa gctgtgtgct tctgccacac tcgagttgac cacagctcca tgatctcgtc   2100
atcactgtag ccactctcct ttgcctctag caatatggag tctggcatgt tagcaggctg   2160
atccatctgc cctctgtaga aaaccagggt gggaaggaca gtgccatctg ccagaatggc   2220
taggactaca tcacaccaag gttcccctgt gcccactgtc tgcagggcat tctcctttcg   2280
atcatcactg ctcagcacct ctgtatccag gaacaaagag atctcatcaa tagccacaat   2340
catagacaag ggtaagtcct ggttgtgaat ctgccgttgt acaaaatcaa tgaagagtcc   2400
tgcattctct gctacatcct taggtagggt gtgggccaca gctcgccggg catggggagt   2460
caggtggtgc cgcagcatga aacgcacagc ccactcatag gagatcttaa accccccttc   2520
caaagaacgt cctattttgg tggccttctg gaacaaggtc tcctcattta caggtagctg   2580
ttgttcgcgc tgggttagca ccyactcagc cagtttctct tctgcctcaa agctcagata   2640
tttgccctct agattctccc cctggnaggc ctgnaaacgt cgaagccaac ggcgaatacg   2700
tcgctgggga tttcggaagt gttcarctgc ctgttctgta ktgcagcata gagcaaacag   2760
tactactcga arcttcttca cagacagctg cycctttttg ccaactccac cactaccacc   2820
accacctgat gctagctcag gttcttgggt gactgggctc ccttcatcct gatcatca     2878

<210> 1246
<211> 1776
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (929)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1476)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1700)
<223> n equals a,t,g, or c

<400> 1246
gngntcttct ccgtactgga gtttgcaccc tcaaatcatt cttttaagaa aattgagttc     60
cagcctccag aagccaagaa gttcttcagc acagtgcgga aggagatggc gctgctggct    120
acctcactgc ctgagggatc atggtcaaga cttttgaaga tagaatggac ctcttctcag    180
ctctcatcaa gggccccact cgaaccccct acgaggatgg cctctacttg tttgacatcc    240
agctccccaa catctaccca gccgtgcccc cccacttctg ctacctctcc caatgcagtg    300
gccgcctgaa ccccaacctg tatgacaatg ggaaggtgtg tgtcagcctc ctgggcacct    360
ggattggaaa ggggacagag aggtggacaa gcaagtccag ccttctccag gtgctcatct    420
ccatccaagg tctgatcctg gtaaatgaac catactacaa cgaagccggc ttcgacagtg    480
accgaggcct gcaggaaggc tatgaaaaca gtcgctgtta caatgagatg gcgctgatcc    540
gcgtggtgca gtccatgacc cagctggtgc ggcggccccc cgaggtcttt gagcaggaga    600
tcaggcaaca ctttagcact ggtggctggc ggctggtgaa ccgtatcgag tcctggctgg    660
aaacccatgc cctgctggag aaggcccagg cactgcccaa cggggtgccc aaggccagca    720
gctcgccaga gcccccagct gtagccgagc tgtcagactc cggccaacaa gaacctgagg    780
atggagggcc agccccagga gaggcctccc agggctcaga ctcagagggc ggtgcccagr    840
gcctggcctc agctagcagg gaccacacag accagacttc ggagaccgca ccaracgcat    900
cggtgccacc cagtgtgaaa ccaaagaanc ggagaaaaga agctaccgga gcttcttacc    960
tgagaagart ggctaccctg acatcggctt ccccctcttc ccactttcca agggtttcat   1020
caagagcatc cggggtgtcc tgacgcagtt ccgggctgcc ctgctagagg caggcatgcc   1080
ggagtgcaca gaggacaagt agctgccagg cacagaggaa agagcatcac cgtgggagag   1140
gccagccgcc gcctgctcac tcccccccgg aatcacccct cttcccatgc ccctctgtcc   1200
ccactgcaaa cccactgccc tcttctcccc aaggtgagtt tgatgctgaa gtgcaagaag   1260
tgtgttgaga tgctgccgtt tctattttga agcgagcttt caacaggcgg gtcccctgtg   1320
gcaaagaaaa tcggaaccct gttgccgatt ttccatttgt caccccagca gaatgtccgg   1380
cacttgctcc cttgctgccc cttctcaggt cagaggcggg tgttccaggg cctgccgcgg   1440
ggctctctgg gccggttccc tgcagacccg cagagnagca catgtgcctt gcatgaagtg   1500
tgggttgcgc caacaattcc cctggtccct ttcaacctgt ttagttcaac tcaagcctcc   1560
ctgtgtccca gaccctcctg ctgccaccac cacccaggtc ctccctagtc ctccagcgtc   1620
aacaytatcc cttgggagtt gtagctgctg tcatkgamty ccggttataa catgggcctg   1680
ttggaccagg ttataggccn tcaggcctgt tggaattggt tttttaagag aggttgggga   1740
ccaggttagg tttccggttg acggccagga gaggtg                             1776

<210> 1247
<211> 631
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (87)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (96)
<223> n equals a,t,g, or c

<400> 1247
catcngcgtt aacgcgcagg cactttttta attaaatacg gactccacta tagggagaga     60
agctatggac gtcgatgcas ggtaagnttg gccctnggag gatcctttag agcgccgccc    120
agttccagcg acataaaatg gacgccgaca accattacgc cgcgattttg catttgtgcg    180
cgtttaaggt tatccaaccc ttcaacatca aaccatttac gtacgcgact gtcgggccag    240
aaccatgcca tgccggtttc taccagcgcc atgccgagtg aacgaaagtt ttcggcaatc    300
atcttctcgc gttcttccgc agaatgctgc gggaaacaaa gttccaggtt tttacgggcg    360
atagattcac gacgtttcag gaatggtcgc gccattgcgc caatacgcgt gccgagaaag    420
cagagaacag gataaggaag ctgtacccaa agccagagta caccaagccc aaaccatgtg    480
agccagtagc gaggatgtag aaactcgcgg gaaaatttgc attgtggaaa catagttacc    540
ttctgtagat acgaattgtt gtatcgcaga agattccatg tcgacccggg aattccggac    600
cggtactgsr ggcgtacatt aaatagtgga g                                   631

<210> 1248
<211> 1307
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<400> 1248
cntncaagcc cgcaattttt tttttttttt ccacatcata taattttatt ggtaaataat     60
tctttagcaa ccagataaaa attaagagag actcatgttc tctccmtgtg tgcacaatgg    120
gggcctccag tacaggctct ggcacatgaa aaaatgctca ataaatgctc actttatgaa    180
aaagtgaatc agtcaatgta cagaccaatt ctctcataag tagaatagtt gacagaccac    240
ctaaattcta tggacctccc ttacacatga ataagaagag cttattatct atccctacaa    300
tgacagatac caatccaacc acctgttcat ggagaatgtt cagttcataa gtggatcttc    360
atcatctcac aaactgacct ttgaggacca agacaattaa catcattcca gccccatctt    420
ttgggtgatt tacgaaaatt tagcacaacg cagcgctcat tgggatcact gggctcacgt    480
ggatgccaga atgtggaact ttcattgtat ggtgtctgat caacccattg ccaatgtcgc    540
tgaccttctg gatctgagag ccccacaaaa taagcagatt cttcttgcag attctggaag    600
atgaaatcct gctcttcttg agtgtttatc accagcaggt gagcctccat tctagcacag    660
tccttctcac tgtcttgcca agatgctgat tcagtagaaa taaagtagca gttggaacta    720
aatgacttcc aattctttgg gcaacagctc caggctgtct cttccacggg catatttttt    780
ttcacacact ccaatgttgt atgaaccagc tcttttgtag tctttttttc aagaagctga    840
gaatattttt gaaagaaaat gacaaaagca ataaagaatg agattgccaa tagcaggaaa    900
aatatcaaca gtgaggcaca aagcagcttg gggaatccgg tattactttt gwgaggggca    960
gtcctctcct tggaagctgc agaagaggct gtgttgatgc ctgaggactt gaattcattt   1020
ttgaacctca cttcagcata agtgatttcc gaagtcataa tgggaagaga gcttctgctt   1080
tcttcagaaa atctgtttca aatctttctt aaaacatctt ataaacagga accaaacatg   1140
gtggtaaatt acctccttcc tttcactcaa ctagtggaga gcagaggcac cagataggca   1200
catatcctca agaggggtct catgagaact aagaaccaca ataaaaacta aaaaccgcag   1260
ttcacagaag ccctttcctc aggaccagta tagtgagcac tctgccg                 1307

<210> 1249
<211> 1945
<212> DNA
<213> Homo sapiens

<400> 1249
tttttttttt tttttttttt tttttttttt tttttttttt tttttttttg ggtgatcagg     60
tctctcttta ctgaaacaca gaacatgtgc caaggtgagt ccaaggacac ctctgggaac    120
aggtgaagcc cctccccaya catacactcc ggtggatgtg agcgagggtc ctgttgccac    180
atctggggty aggggcttgg acatgctgcc cttcatggga accttctggg tacctctcag    240
cacagtaacg cagctgcagt ctgtcggtgg gggcccaggc taggggcagc accctctttt    300
ggcatacggg acatgcctgg ctgcagctga tgtccgttag cctctcctga cacgcagtaa    360
ggagacctgg aagtgaggcg cgtgggcgtg gagttcccgg tggagctgct gcatcagcct    420
ttctgccact ctggggtcag tgaggtcttc cggggaagcc acactcagcc gcaggaggag    480
gaaacctcca ttttcacctg cactcacgtc tgtggtcggc ctcgtccggg cagtcgtggg    540
cgtggctgtt gggggcttca tcgtggtctt cgctgaggtt gtgatcttgg ctaaggtgct    600
gttcgtccct cggctgctgt tggttgtagt cggagggaca gaaggaagag ggtccctgct    660
ggtggggaag ggccccttgg ttgcgatgtc catggtcggt gtctctgaag gggtgaagtt    720
cttgagggcg gcttccgagg ggctgtagga ggaagcagag ctcccagcaa aggaagttgt    780
tttgcccact gctgacccag cctctatgga gaccggagct gctcctgaga ctttgacgta    840
acttggtgtc tcaacagaga gggctgaggt ttcttccagg ggattcctgc taactgtgac    900
cagagctcca ctgagggtcg tggcccyggg tgctgtcact tctctttctr tggygctgtt    960
agtggggagt ggggtcccaa ccgtggcatg aggtgcagct gactctgtgg tgccggctgt   1020
ggacagggtc tcggcagagg ctgtgacctc agtgatgtgt ggttttgctt cagtggagtc   1080
aggcagagct ggtggatcgg aggtggacga ggccttcacc ccttccgtgg ggatgagatc   1140
tatgtctgag gccccaggga tgctggaagt ygttgtttct atttctgtga tgctgcaatt   1200
aataacctcg atgtttgtga cagtcaccag ggcttcagcg aggagagtga crtcagatcc   1260
cggggaccat gasggggtga tgactggatg ggggccgtcg gaagaggcgc tgctctctga   1320
ggcccgtgac ggggtgatga ctggatgggg gccgtcggaa gaggcrctgc tctctgagga   1380
caggccctta gcttctgtgs aggtgtgagc caatgtcaat atgtccattg tgagtgtctt   1440
tgcctyttaa gagctgtcat cggtgyaaag ggtgtcaaag atggcttccc tsggatcact   1500
gcctgtgatg gtctgaactg tggtcattcy agctccctcg gggctgccac tggcggytga   1560
tgtctccacr gaggtggcga tcagcaccat gaagttggga gatgtttttg tgaaactcct   1620
ggtctctctt gcaggggaaa ttctcttggc tcccctggtc tctgcttctg gaatggggcc   1680
ggctggggtt gaggccctag aagaggtctc agcgctcagc gtttgagttt ccagagcggc   1740
gtggcccggt gctagagtca tagcgggcac ttctgtgtcg tccgttgtca tcgcagtgtc   1800
tgctctgcgg gtgctggggc ctgcagagct cccagagacc ccaacctccc agcagaagaa   1860
gaaaaggggc agagccagac cccagagaca gcccatccta gccggccacc gctgctccac   1920
agaactgctg gccggacgcg tgggc                                         1945

<210> 1250
<211> 1308
<212> DNA
<213> Homo sapiens

<400> 1250
ggcgagagaa tcatcatggg atcatgtaaa aactagtgct acaaatcgtt tctcaagaat     60
gcactgtcct actgtgcctg atgaaaaaaa tcattatgag aaaagttctg gttcttcaga    120
aggtcaaagc aaaacagaat ctgatttttc caacctagac tctgaaaaac acaaaaaagg    180
acctatggag actggattgt ttcctggtag caatgccact ttcaggatac tagaggttgg    240
ttgtggagct ggaaatagtg tgtttccaat tttgaacact ttggagaact ctccggagtc    300
ctttctgtat tgttgtgatt ttgcttctgg agctgtggag ctcgtaaagt cacactcgtc    360
ctacagagca acccagtgtt ttgcctttgt tcatgatgta tgtgatgatg gcttacctta    420
cccttttcca gatgggatcc tggatgtcat tctccttgtc tttgtgctct cttctattca    480
tcctgacagg acattgttta tctgaaaatt tttatgttcg aggagatggt accagagcat    540
atttctttac aaaaggggaa gtccacagta tgttctgcaa agccagttta gatgaaaagc    600
aaaatctggt tgatcgccgc ttacaagtta ataggaaaaa acaagtgaaa atgcaccgag    660
tgtggattca aggcaaattc cagaaaccat tgcaccagac tcagaatagc tccaatatgg    720
tatctacact cctttcacaa gactgaactt tgtaacatgt taaggtacaa agccagagga    780
ctgtgctatt caaggactac tgtaagtcta ttgtttctca aaagacaatg agaaaaaaag    840
aagagaattt gtatttcctg ccgttttgtc ataggtgagc tcctttgtgc attttaagca    900
catgtaagtg gttcagcaca gtatgccttt ttctgtgctt tgaaaacttg atatgctcaa    960
gcttgtttga atttattaca tctaaccatt ttgcttgttc cttgattttt ataagcattc   1020
aattaagtta gtattatgtc aagtaatttt gagaaaatgt aacttgacat tttttgcaag   1080
taaaaaaaat tgtttatttg tttaggctta gtaaaccagt tcccaaacac agtcagactc   1140
ttcccattgt catctgattg cagagagaaa gcacacctta tttccaggga aagctacaac   1200
aagcccaagg tcaawgtgta ttattttttg tcttgttgtw ggtctatttt ctcccaattt   1260
ttttttgaaa ttcagaggct catatctgaa atagaatttt tagttcct                1308

<210> 1251
<211> 1075
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<400> 1251
ccgggncccc cctcgngttt tttttttttt ttttttttta aatatgacag tcttggattt     60
atttgtaagt gtttaaaatg tccaatattc agaagttgtc aggtgttctt accacctccc    120
cactccctca accagtccct gcttccaggg tccaggagaa gcagtgttca ggcagagtag    180
tctcttgcca gagcagaaca aggagtcctg gtggccaagt ggcaagtatg caggctgggc    240
tggtccctgg tgggacttct cctgggcttt tcctcccatc atcttccttc acgtgtctct    300
cagccctggc agagtttgga gctgataccc tgggtcatgg ccacagtcca gttcactggg    360
tggatgtgtc cctggcttct gtccatgcca ggctgcagcc cagagggcgc tggctgctag    420
aatcttgatg agaaagatgc aggccaggag gagaaggatg gaagtgggtg ggaaggggat    480
ttctccttcc aagaggctcc tggagatgct gtgctccaca tgggcatcct cgaagctctc    540
agactccccg gggaaccaga gatctccagc atcccggtga tccagggggt ctgccagcac    600
ctccaccagg accttcctga gggtgtcagc ctcactgcca tggaggctct ggcactggta    660
gagacccgca tcatggggtt gtagattccg cagcgtaatg gtgagagtgc cacccagggt    720
atcgtctgtg atggctgtgc tcccattcca cctcctcagg aaggacagca gccacaagtt    780
gtgcgtgctg accacacgct ggcatgggcc cttctctccc agctggcggc accaggcctt    840
gcgcctcccc cagtgcttca tggagtcata ggggcaagac acctgcaggg actggcccgc    900
cacgccctgg aacactgtgg tgttgtgggc tccggacagc tctgtgacaa agagtaagat    960
gagcagccgg agaggctcca tgccaccctt ccccagccaa gggcagaagc agagtgcctt   1020
gtgcaagatc tcgtctttcc cttgaactgc agaaaagaga ggatcaggct cgtgc        1075

<210> 1252
<211> 1913
<212> DNA
<213> Homo sapiens

<400> 1252
gagggacgat tgggttaccg ggaccccccc tcgagttttt tttttttttt tttttttttt     60
ttttgggcaa aaaagctttt tattttcccc cacattccag ctcttcactt tttctaaaac    120
cttttccaac tcagagccaa ggcccaagaa gttgattcac acctgagaaa caagtcggga    180
actaggccag tgccctcaga gccgggttct agaccagtgg gactcccggc gcgggtggaa    240
gcacatagca gtgacacagc agagaaggcc acagaagaga agcaggaagg agcccaagac    300
cagcagcctg gagccacaca gagccagctc ctccgaggtg agcagcttgg tcagcacaag    360
gccttcatgg ctccagacac taacacattc ctcacccatt ctagggctca gggtggcatt    420
tccagccccc tcctctgagc aggatatggg tggctggctg gagggtagga ttcctggaac    480
agcactaaaa tataggcagg ttcctgcagt cctttctgtg gtcaccctgg ctgtgataag    540
gaccagttgt cctgcagaag atcctttcaa tcccatctga cttcccagga ctgtggcctg    600
gaatgtccgg gtcttgttcc tgtctggacc gtctccgaag ttcaaggtgg tcagcaagcc    660
cacgacgtga gaccctcgcc acttccctgt gactgtccca ttcctgggac acagggtcag    720
ctggccaaaa gatctcaaaa aagagaccca gtcctggggg atgtcagggc tgcgcaggcc    780
agtcctgtgg gtgaggagga agctgccaag gcccaggcca gagaggccaa ggagcagcag    840
gatcaaagtg gcacagacca gaggtgggtg gtgggccaga cacaggtgca ggttgtgccc    900
tgcctggcag ttgcccatgg ggagcagagg gggctgagcc tccggggaga gcctgctgga    960
agacagggag ggagaatggg acaagagcac cgcttttacg caaagagaaa agaaagctca   1020
gagaagacaa aggacttccc aaggccacac agtaagtggc agagccagaa caagaatcca   1080
aggttcccga ctccaaaagt tcaactccct gcactgctgg ataaatattt gctgcatttc   1140
atttctgaag taatctaagt ggaggcagag cagtgtactc cgtgctggaa gaaggaaact   1200
gaaagggaga cttctyagct ggagaaacag gaagcactgt tctggggcga ggatttggct   1260
gaggaatagt tccagccaga gcccagacaa gggaagactc tggagaagaa ctccactgtg   1320
cagctaaacg gctagatctg aatccctttc tgttattcac tgactctgtg agcttaagaa   1380
tccatgaaat gggagttctg agaacaccaa gtaataagga ttaaacgtgg cggatgaagc   1440
agtctgcgtg gtatttggcc atgcaggaat tcaacaaatg tccacttcct ttctctttct   1500
cgtacagatc ctcaaaaccg ggtaaggcga ggcaaaaaat actgtgaggg aaactgaggc   1560
tcgcggactt taacacagga ggggtagggc caagatctga accccgcctc ctgcttccaa   1620
gtggggtgct ccttcccacg caaggtgcga cggcctgatg gaaaagaact tctggaaggc   1680
gaagagataa acaggggtcg ggggaaaaga agggagccac ggaaatgtag gtgtcacaaa   1740
tgctcagccc tgcyccgcct cccgtccggc tggaaggggg ttaaagggag gggagggcag   1800
agtcwgaggg tccgccgccg ctggtgcacc tgagcacccc ctccccggaa agcccccgcc   1860
ccgaacgatt gcaacgccct cgtcccctcc cggtctcgcg cgtcggatcc gcc          1913

<210> 1253
<211> 1795
<212> DNA
<213> Homo sapiens

<400> 1253
acccacgcgt ccgccgggga scacgcgtct catccatggc ttccgcggac tcgcgccggs     60
tggcagatgg cggcggtgcc gggggcacct tccagcccta cctagacacc ttgcggcagg    120
agctgcagca gacggaccca acgctgttgt cagtagtggt ggcggttctt gcggtgctgc    180
tgacgctagt cttctggaag ttaatccgga gcagaaggag cagtcagaga gctgttcttc    240
ttgttggcct ttgtgattcc gggaaaacgt tgctctttgt caggttgtta acaggccttt    300
atagagacac tcagacgtcc attactgaca gctgtgctgt atacagagtc aacaataaca    360
ggggcaatag tctgaccttg attgaccttc ccggccatga gagtttgagg cttcagttct    420
tagagcggtt taagtcttca gccagggcta ttgtgtttgt tgtggatagt gcagcattcc    480
agcgagaggt gaaagatgtg gctgagtttc tgtatcaagt cctcattgac agtatgggtc    540
tgaagaatac accatcattc ttaatagcct gcaataagca agatattgca atggcaaaat    600
cagcaaagtt aattcaacag cagctggaga aagaactcaa caccttacga gttacccgtt    660
ctgctgcccc cagcacactg gacagttcca gcactgcccc tgctcagctg gggaagaaag    720
gcaaagagtt tgaattctca cagttgcccc tcaaagtgga gttcctggag tgcagtgcca    780
agggtggaag aggggacgtg ggctctgctg acatccagga cttggagaaa tggctggcta    840
aaattgcctg agaggcagct ctaaagcaca agacctggat gtgtgacaca cagttttgga    900
aaaaggtctg tggtagtctg gagttgatga ggaaggggta caagatgtgg ttagaaacat    960
ttctttgttc tggaaacaaa gtactgttga aaccagcttg gaattttttt tttttttttt   1020
tttaagttca gttctccctt atggctgcct ttcaaacaag taccttttat ctgatgcctg   1080
tatcttccct ttgttaaggt gtaacttgat gtagggtcaa ggtttttgtg acaacaggca   1140
gactccacac agagaggata tgatgagaat atggccatca cctgaaaagt tttcttatct   1200
tctgtgcttt tggtccctgg aaacaaatcc gcctatgtat gaagctagtt gatttccagt   1260
tgcactattt ccagttgcct ctgaagttca caggcaatac attgtctagt cctttgcgaa   1320
tttctctgat ttgtgggcac agttatgaag tttccccaca tgtgaagaca ggtacaaaat   1380
agcagagcca agcagacagt gggtctattc ttcattagct cagtgacttg tccacactcg   1440
tcttagcact tacgtttcaa aagcttgtca caaacccttg gagtcattcc cagataatag   1500
aactggaaat gataaatccc ctaatgccaa gggtctagtg tgttcttagt ggttatactg   1560
ggaagtgtgt ggagatttag gtgctgctct gctgctctgg atggctgaag gctcctgggc   1620
catcttcatg tgctgcttga agagctccta ttttgtactc ctggctagaa tgctgtggaa   1680
caaatacaaa gtgaaaaaag ttctctgtag atttctgaag tgcatattca ttgatgccaa   1740
gaaaaaaaaa aagttgcctt tttgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa        1795

<210> 1254
<211> 825
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (760)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (766)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (789)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (806)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (809)
<223> n equals a,t,g, or c

<400> 1254
atagcttcgc ttaagctatt taggtgacac tatagaaggt acgcctgcag gtaccggtcc     60
ggaattcccg ggtcgaccca cgcgtccgga cagccagcca ccacaatgaa agaaatcaaa    120
ccaggaataa cctatgctga acccacgcct caatcgtccc caagtgtttc ctgacacgca    180
tctttgctta cagtgcatca caactgaaga atggggttca acttgacgct tgcaaaatta    240
ccaaataacg agctgcacgg ccaagagagt cacaattcag gcaacaggag cgacgggcca    300
ggaaagaaca ccacccttca caatgaattt gacacaattg tcttgccggt gctttatctc    360
attatatttg tggcaagcat cttgctgaat ggtttagcag tgtggatctt cttccacatt    420
aggaataaaa ccagcttcat attctatctc aaaaacatag tggttgcaga cctcataatg    480
acgctgacat ttccatttcg aatagtccat gatgcaggat ttggaccttg gtacttcaag    540
tttattctct gcagatacac ttcagttttg ttttatgcaa acatgtatac ttccatcgtg    600
ttccttgggc tgataagcat tgatcgctat ctgaaggtgg tcaagccatt tggggactct    660
cggatgtaca gcataacctt cacgaaggkt ttatctgttt gtgtttgggt gatcatggct    720
ggtttgcttt gscaaacaty atyctgrcaa atggtcaagn caaccngagg acaaatattc    780
ctgaactgnt tcaaaactta aaaggnccnt ttgggggggc aaaaa                    825

<210> 1255
<211> 866
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (627)
<223> n equals a,t,g, or c

<400> 1255
tcaagtacag caattacgtg cggcccatct gcctgcctgg cacggactat gtgttgaagg     60
accattcccg ctgcactgtg acgggctggg gactttccaa ggctgacggc atgtggcctc    120
agttccggac cattcaggag aaggaagtca tcatcctgaa caacaaagag tgtgacaatt    180
tctaccacaa cttcaccaaa atccccactc tggttcagat catcaagtcc cagatgatgt    240
gtgcggagga cacccacagg gagaagttct gctatgagct aactggagag cccttggtct    300
gctccatgga gggcacgtgg tacctggtgg gattggtgag ctggggtgca ggctgccaga    360
agagcgaggc cccacccatc tacctacagg tctcctccta ccaacactgg atctgggact    420
gcctcaacgg gcaggccctg gccctgccag ccccatccag gaccctgctc ctggcactcc    480
cactgcccct cagcctcctt gctgccctct gactctgtgt gccctccctc acttgtgggc    540
cccccttgcc tccgtgccca ggttgctgtg ggtgcagctg tcacagccct gagagtcagg    600
gtggagatga ggtgctcaat taaacantac tgtttgaaaa agaaaaaaaa gtcttattag    660
cgcgcactta tctttatgag gtattagctg catgcgtcgt taagcgtatg gacatggtac    720
catatgctag atcgttgatg tatagaagcc cgtcttcaat gctatgatga ccttaggggt    780
agggtgttgg caataccgcg tttctttcag gctcatatgc tggtttccaa ttgtggcgag    840
ctgggtaatt cagtggctga acaacc                                         866

<210> 1256
<211> 1112
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (921)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (932)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1082)
<223> n equals a,t,g, or c

<400> 1256
aattcggcag agccatcttg ctctaagtga aagtgaaaga aaagtcggca gcagagggaa     60
cagggaagaa acctaaaggc tgcaggctgc caggtgtgct tggagagccc ccttcttccg    120
ccgggcctcg caagcagcgt aggactgtgg agaagggcgg tgggcaagga gggaactcga    180
gagcagcctc catgggcaca caggagggct ggtgcctgct gctctgcctg gctctatctg    240
gagcagcaga aaccaagccc cacccagcag aggggcagtg gcgggcagtg gacgtggtcc    300
tagactgctt cctggygaag gacggtgcgc accgtggagc tctcgccagc agtgaggaca    360
gggcaagggc ctcccttgtg ctgaagcagg tgccagtgct ggacgatggc tccctggagg    420
acttcaccga tttccaaggg ggcacactgg cccaagatga cccacctatt atctttgagg    480
cctcagtgga cctggtccag attccccagg ccgaggcctt gctccatgct gactgcagtg    540
ggaaggaggt gacctgtgag atctcccgct actttctcca gatgacagag accactgtta    600
agacagcagc ttggttcatg gccaacatgc aggtctctgg agggggacct agcatctcct    660
tggtgatgaa gactcccagg gtcrccaaga atgaggcgct ctggcacccg acgctgaact    720
tgccactgag cccccagggg actgtgcgaa ctgcagtgga gttccaggtg atgacacaga    780
cccaatccct gagcttcctg ctggggtcct cagcctcctt ggactgtggc ttctccatgg    840
caccgggctt ggacctcatc agtgtggagt ggcgactgca gcacaagggc aggggtcagt    900
tggtgtacag ctggaccgca nggcaggggc angctgtgcg gaaaggcgct acctggacct    960
gcacaactgg gcatggcagg atgctcctca cctgccggct catatacaga cagggactac   1020
ttgcaataca ctctttacga ctcacaatat cactcactcc actcctaata atactggaac   1080
anttctcccc ctctcaatgt gtatacctga tg                                 1112

<210> 1257
<211> 1895
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (61)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1702)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1836)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1841)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1846)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1856)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1876)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1882)
<223> n equals a,t,g, or c

<400> 1257
cacaggaagc agctatgacc atgattacgc caagctcgaa attanccctc actaaaggga     60
ncaaaagctg gagctccacc gcggtggcgg ccgctctaga actagtggat cccccgggct    120
gcaggaattc ggcacgggat caggattttt tttttattac ccagccgatg acaatgtata    180
tcgaagttag tttaagaaca aaggatgtgc acacttgttt taaagtagtt ttggttatga    240
taataagaat tataagaggg accaaatatc aaatgcaaga aaatggtcct gaatgccaat    300
acaatcagaa taagaaatgc ataaatagcg acttgcttga agctgaaatc aactcctttt    360
tggatgcctt tcttgtcttt tgaagaacac atgttgtagt atgtgtttct ctccatatcc    420
tgtgtgtttc attgtaatag tcttgctgat tgattttgtt ggctgcaagm aaagtgataa    480
aatgccagtg ggtgcctgtg ccagggaggt caggactgga ctttcccact tggctctgtt    540
ttgatgcatt tagcagattg attccaaccc tctttggaga ctctgaccta caaaagtgtc    600
tgttatcttt gagagctcca gggaaagcta tggacctttc tagatctttt cccacctttt    660
ggcccatcag atattgcctt gtccacagca gaacttgacg attcatcata gaagcctatg    720
gttttattta ttgacactgc tgtacaattt tccctgtagc gagtcatagt tggctgaaga    780
gagagtcgaa gattaagtac aaaactttct aaacatcctg ttttccctca agacagggca    840
ctgttcttaa taaactgaac attcttttgc actggccctg gggcaagggt gtcccaaaag    900
ctttgacagg ggtgccattt ggtcataaac agtgtggtaa tagggtggag tcagaaagaa    960
attctctcat cccttttaca actccaggca attctagaac caacccttgg gaacccaggg   1020
aaagaactct gaaatgatac gctggctgag gtttgccgtg gccacacctc agggttaagc   1080
attgaaggag ctaggcaaag agtgtgtgtg tttagctaca aactaagtca cagatcaaga   1140
ggcttttggt attcttccat ttttgcttag aattctatga tggtttttga aatatattgt   1200
ccttacttta tgttcttacc tgtaatctca taagtttctg gtaaatttag cttttgccag   1260
gttccggtgg gtcttaccca gagatggtca gagtaaatga acaaaagaag gaattgatta   1320
ggatgtgaaa cttcagatac gctcacaggc cttcaagccc tagaaagtag tatgccagtg   1380
aattttctag tcctctctac actttgtaca gatgaagaaa ccgagaccca gggaactcaa   1440
ccaaggtttc ttgccattcc tccagtcccc cagttaaaaa aaaaaaaaaa aaaaaactcg   1500
agggggggcc cggtacccaa ttcgccctat agtgagtcgt attacaattc actggccgtc   1560
gttttacaac gtcgtgactg ggaaaaccct ggcgttaccc aacttaatcg ccttgcagca   1620
catccccctt tcgccagctg gcgtaatagc gaagaggccc gcaccgatcg cccttcccaa   1680
cagttgcgca gcctgaatgg cngaatggca aattgtaagc gttaatattt tgttaaaatt   1740
cgcgttaaat ttttgttaaa tcagctcatt ttttaaccaa taggcccgaa atcggcaaaa   1800
tcccttataa atcaaaagaa tagaccgaga tagggntgag ngttgntcca gtttgnaaca   1860
agagtccact attaangaac gnggactcca acgcc                              1895

<210> 1258
<211> 1803
<212> DNA
<213> Homo sapiens

<400> 1258
gcacgggccg gaggtcccgg ggctgctggg tgcgggcggt gggctgcgcg ttgtccgctg     60
gactgggtcc cggtcacgcc ccgccaagcc ccgcccctca ggccggggcg cgaccgcgga    120
tccgcagttc ccgggccagc ctggggcggc cggccaggaa ccacccgtta aggtgtcttc    180
tctttaggga tggtgaggtt ggaaaaaggc tcctgtaacc ctcctccagg atgaaccacc    240
tgccagaaga catggagaac gctctcaccg ggagccagag ctccatgctt ctctgcgcaa    300
tatccattcc atcaacccca cacaactcat ggccaggatt gagtcctatg aaggaaggga    360
aaagaaaggc atatctgatg tcaggaggac tttctgtttg tttgtcacct ttgacctctt    420
attcgtaaca ttactgtgga taatagagtt aaatgtgaat ggaggcattg agaacacatt    480
agagaaggag gtgatgcagt atgactacta ttcttcatat tttgatatat ttcttctggc    540
agtttttcga tttaaagtgt taatacttgc atatgctgtg tgcagactgc gccattggtg    600
ggcaatagcg ttgacaacgg cagtgaccag tgccttttta ctagcaaaag tgatcctttc    660
gaagcttttc tctcaagggg cttttggcta tgtgctgccc atcatttcat tcatccttgc    720
ctggattgag acgtggttcc tggatttcaa agtgttacct caagaagcag aagaagaaaa    780
cagactcctg atagttcagg atgcttcaga gagggcagca cttatacctg gtggtctttc    840
tgatggtcag ttttattccc ctcctgaatc cgaagcagga tctgaagaag ctgaagaaaa    900
acaggacagt gagaaaccac ttttagaact atgagtacta cttttgttaa atgtgaaaaa    960
ccctcacaga aagtcatcga ggcaaaaaga ggcaggcagt ggagtctccc tgtcgacagt   1020
aaagttgaaa tggtgacgtc cactgctggc tttattgaac agctaataaa gatttattta   1080
ttgtaatacc tcacagacgt tgtaccatat ccatgcacat ttagttgcct gcctgtggct   1140
ggtaaggtaa tgtcatgatt catcctctct tcagtgagac tgagcctgat gtgttaacaa   1200
ataggtgaag aaagtcttgt gctgtattcc taatcaaaag acttaatata ttgaagtaac   1260
acttttttag taagcaagat acctttttat ttcaattcac agaatggaat ttttttgttt   1320
catgtctcag atttattttg tatttctttt ttaacactct acatttccct tgttttttaa   1380
ctcatgcaca tgtgctcttt gtacagtttt aaaaagtgta ataaaatctg acatgtcaat   1440
gtggctagtt ttatttttct tgttttgcat tatgtgtatg gcctgaagtg ttggacttgc   1500
aaaaggggaa gaaaggaatt gcgaatacat gtaaaatgtc accagacatt tgtattattt   1560
ttatcatgaa atcatgtttt tctctgattg ttctgaaatg ttctaaatac tcttattttg   1620
aatgcacaaa atgacttaaa ccattcatat catgtttcct ttgcgttcag ccaatttcaa   1680
ttaaaatgaa ctaaattawa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1740
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaggg ggggccsttt   1800
tag                                                                 1803

<210> 1259
<211> 3140
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1628)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1642)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1656)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2094)
<223> n equals a,t,g, or c

<400> 1259
tgntncgagt cacccaggtg nagaatgagg agaaactgaa ggagctagag cagatttgat     60
cccaaactct ttctkgtttt ccttcttgga cttatgctat ttttttgtgg agacttgctg    120
agcagaagtc aaattttcta ctactctact gggatgactg tgggaattgt ggcctctctg    180
ctaatcatca tttttatact atctaagttt atgcctaaga aaagtcccat ttacgtcatc    240
ctggtgggag gctggtcttt ttctctgtac ctcattcaac tagtttttaa aaatttacaa    300
gagatctgga ggtgttactg gcagtatctt ttaagttatg tcctcacagt tggattcatg    360
agttttgcag tatgttacaa gtatgggccc ttggagaatg aacgaagtat caacctgctg    420
acctggacct tgcagctgat gggcctgtgt ttcatgtatt ctggcatcca gataccacat    480
attgcccttg ccattatcat cattgctctt tgtactaaga acctggaaca ccctattcag    540
tggctgtaca tcacctgcag aaaggtgtgt aagggagcag aaaagcctgt tccccctcgt    600
ctcctgacag aagaagaata tcggatacaa ggagaggtag aaacccgaaa ggctttagag    660
gagctccgag aattttgtaa cagtccagac tgctctgctt ggaagactgt ttctcgaatc    720
cagtctccaa aaagatttgc tgactttgtg gaaggctctt cccacctcac gccaaatgaa    780
gtttctgtcc atgagcagga gtatggatta gggagcatta ttgcccagga tgaaatctat    840
gaggaagcat cctctgagga ggaggactca tattctcggt gtcctgctat cacacagaac    900
aactttctaa cctaggtagt ggtcagttat ctttacgtgg actggcttgg tgccttggtc    960
catgttgcat gtgttgtgca attgctttca accctttgaa acagagtgag atagataggg   1020
tagaaattct cctactgaaa taagaggcct aaaaaggcct ccctttggaa atgggaggtc   1080
tctatgggat ccctgaggaa ggagagtgga taaagtagtg aatgctgggt agttcacttc   1140
ccattggtta agctaacagc ccacttttat gtttccagag aaattggatg gccacagcta   1200
gcatggcatt ctagctcctt cttgaaagtt gattcaatca tggcatttct gtcactggct   1260
ggctctccaa agtaagaact gttgttaagt gcaggaatgc ttttagacta taggctgcaa   1320
cttccagaga gaaatccaca aatctgagcc tccttcactc cagcttttat ttcrgtgact   1380
ttagaataat tattgattta actgttttgg gaggaaaata gatttttatt gttttgtttt   1440
ttaaatgaat gtcttttaaa aamcwtamca aactcatgtt ccagaaccag caagtgctcc   1500
agagtgacac accccctagg cccctacata tttattaata tggattatcc attaaagccc   1560
caggagctgt tgttttaagc tttgatttag ttctcataca tatgatagaa agtcctattt   1620
gcctttanga acatgcctgt angctcttct gcaggntgag atgttctggg ctttttatta   1680
tattcaactt tcaattccat cttaaaaaac atttgtwttc ttctcttccc attcttcctt   1740
accctgcctt tgccctttca ggaagggtca gttcccttac ctgtgaacta tgtatgttca   1800
gagtagcatt attcctgcta gctaggagaa gtcatcttgt ttaggggatt tggatgcttt   1860
ttatacgttc tccattttcc tgtcattggg tcatgttatc tttgagttgc tatgaaatca   1920
ggaaactgtc tccttttcct ttcccttcct ttgtctacat gctctgtcca ttcctttcag   1980
ccttttctca ccacccatac tcccccaaat ctgggtaatt tttaagcctt gaaactatgt   2040
agtttcttga tacacaattt gtagttatgc agcagccaca atttgcattg ccanggaaat   2100
argctccagg ttatcttcat gcctctgggt gctcattcag ctgtcaagtt tccatgaact   2160
tacacttatt tatgattgcg tttctgacct gagatgtatg ctgcctgtta ttgcagtagc   2220
attagtttca gattcttttg ccattgcaaa gtacccctta taaaccagca atgtcatctg   2280
tgaggaagca aattctcaag tgtctgtcat ttacttggtt ctttttcttt gtggtcttca   2340
cccttatacc ctggaaaagt ctgtaattac cttagccagg aagatagatg gtcatggcaa   2400
gcgcacagca ccagacttac tggctcacca agatgatgga aaaaggcaga tgatttttta   2460
aaaagccgta atgactcctt tagaccagcc atttagcgtg gtaattttga aaggcctagc   2520
tccattgcag acttccaaag ggtcagctct gagactgccc tccaggtggg cagttgatta   2580
tttccaccag tgttttccag agccttaaac tgtcctaagt gacaactacc tcagttggca   2640
ggaaagagac atatagtaga aagtgaaaaa tgagcagtat ttgggcagat gctatgggtt   2700
acagttgaag ggtaaaagga actttacatt gggaaacctt tatacccttg tgaattatgt   2760
acatggtaaa atgttctctc tctacaaaga actattaaaa cttctgaaat atactatttt   2820
ttaccttatt tatagaaatt gagacctagc atatttaagc ataagtttat tttaaaaaat   2880
aattcaactc gtgcaagtgg tctcaggatt ctctggagat tttggtgcct cccctactta   2940
gggaggtgat agcttgccta waagggtgac ttttccygat catgtcttta tttcaatgag   3000
aaagcactgt gaaattgtga aagawtctcc tctttctctg tttaataaac ccccatgaaa   3060
tataaaaaaa aaaaaaaagg gcggccgctc tagaggatcc ctcgaggggc ccaagcttac   3120
gcgtgcatgc gacgtcatag                                               3140

<210> 1260
<211> 2369
<212> DNA
<213> Homo sapiens

<400> 1260
gatgaagtgg agcwgtgagt gtgagcctca acatagttcc agaactctcc atccggacta     60
gttattgagc atctgcctct catatcacca gtggccatct gaggtgtttc cctggctctg    120
aaggggtagg cacgatggcc aggtgcttca gcctggtgtt gcttctcact tccatctgga    180
ccacgaggct cctggtccaa ggctctttgc gtgcagaaga gctttccatc caggtgtcat    240
gcagaattat ggggatcacc cttgtgagca aaaaggcgaa ccagcagctg aatttcacag    300
aagctaagga ggcctgtagg ctgctgggac taagtttggc cggcaaggac caagttgaaa    360
cagccttgaa agctagcttt gmaacttgca gctatggctg ggttggagat ggattcgtgg    420
tcatctctag gattagccca aaccccaagt gtgggaaaaa tggggtgggt gtcctgattt    480
ggaaggttcc agtgagccga cagtttgcag cctattgtta caactcatct gatacttgga    540
ctaactcgtg cattccagaa attatcacca ccaaagatcc catattcaac actcaaactg    600
caacacaaac aacagaattt attgtcagtg acagtaccta ctcggtggca tccccttact    660
ctacaatacc tgcccctact actactcctc ctgctccagc ttccacttct attccacgga    720
gaaaaaaatt gatttgtgtc acagaagttt ttatggaaac tagcaccatg tctacagaaa    780
ctgaaccatt tgttgaaaat aaagcagcat tcaagaatga agctgctggg tttggaggtg    840
tccccacggc tctgctagtg cttgctctcc tcttctttgg tgctgcagct ggtcttggat    900
tttgctatgt caaaaggtat gtgaaggcct tcccttttac aaacaagaat cagcagaagg    960
aaatgatcga aaccaaagta gtaaaggagg agaaggccaa tgatagcaac cctaatgagg   1020
aatcaaagaa aactgataaa aacccagaag agtccaagag tccaagcaaa actaccgtgc   1080
gatgcctgga agctgaagtt tagatgagac agaaatgagg agacacacct gaggctggtt   1140
tctttcatgc tccttaccct gccccagctg gggaaatcaa aagggccaaa gaaccaaaga   1200
agaaagtcca cccttggttc ctaactggaa tcagctcagg actgccattg gactatggag   1260
tgcaccaaag agaatgccct tctccttatt gtaaccctgt ctggatccta tcctcctacc   1320
tccaaagctt cccacggcct ttctagcctg gctatgtcct aataatatcc cactgggaga   1380
aaggagtttt gcaaagtgca aggacctaaa acatctcatc agtatccagt ggtaaaaagg   1440
cctcctggct gtctgaggct aggtgggttg aaagccaagg agtcactgag accaaggctt   1500
tctctactga ttccgcagct cagacccttt cttcagctct gaaagagaaa cacgtatccc   1560
acctgacatg tccttctgag cccggtaaga gcaaaagaat ggcagaaaag tttagcccct   1620
gaaagccatg gagattctca taacttgaga cctaatctct gtaaagctaa aataaagaaa   1680
tagaacaagg ctgaggatac gacagtacac tgtcagcagg gactgtaaac acagacaggg   1740
tcaaagtgtt ttctctgaac acattgagtt ggaatcactg tttagaacac acacacttac   1800
tttttctggt ctctaccact gctgatattt tctctaggaa atatactttt acaagtaaca   1860
aaaataaaaa ctcttataaa tttctatttt tatctgagtt acagaaatga ttactaagga   1920
agattactca gtaatttgtt taaaaagtaa taaaattcaa caaacatttg ctgaatagct   1980
actatatgtc aagtgctgtg caaggtatta cactctgtaa ttgaatatta ttcctcaaaa   2040
aattgcacat agtagaacgc tatctgggaa gctatttttt tcagttttga tatttctagc   2100
ttatctactt ccaaactaat ttttattttt gctgagacta atcttattca ttttctctaa   2160
tatggcaacc attataacct taatttatta ttaacatacc taagaagtac attgttacct   2220
ctatatacca aagcacattt taaaagtgcc attaacaaat gtatcactag ccctcctttt   2280
tccaacaaga agggactgag agatgcagaa atatttgtga caaaaaatta aagcatttag   2340
aaaaaaaaaa aaaaaaaaaa aaaactcga                                     2369

<210> 1261
<211> 1772
<212> DNA
<213> Homo sapiens

<400> 1261
cacgaggaga gggcgggcca gggmcgcact ccggagactc gcggttgcta cgcgcaccat     60
ggctggagag gtacttctca gccctctagc tccaactgag aacccagcca gtcaggaagt    120
cgctacttcg ggaacaccaa ccaatcaggg ggccgtcacc tgctgaagga gtccttcggc    180
ggctgttgtg tcagtggcct gatcgcgatg gggacaaagg cgcaagtcga gaggaaactg    240
ttgtgcctct tcatattggc gatcctgttg tgctccctgg cattgggcag tgttacagtg    300
cactcttctg aacctgaagt cagaattcct gagaataatc ctgtgaagtt gtcctgtgcc    360
tactcgggct tttcttctcc ccgtgtggag tggaagtttg accaaggaga caccaccaga    420
ctcgtttgct ataataacaa gatcacagct tcctatgagg accgggtgac cttcttgcca    480
actggtatca ccttcaagtc cgtgacacgg gaagacactg ggacatacac ttgtatggtc    540
tctgaggaag gcggcaacag ctatggggag gtcaaggtca agctcatcgt gcttgtgcct    600
ccatccaagc ctacagttaa catcccctcc tctgccacca ttgggaaccg ggcagtgctg    660
acatgctcag aacaagatgg ttccccacct tctgaataca cctggttcaa agatgggata    720
gtgatgccta cgaatcccaa aagcacccgt gccttcagca actcttccta tgtcctgaat    780
cccacaacag gagagctggt ctttgatccc ctgtcagcct ctgatactgg agaatacagc    840
tgtgaggcac ggaatgggta tgggacaccc atgacttcaa atgctgtgcg catggaagct    900
gtggagcgga atgtgggggt catcgtggca gccgtccttg taaccctgat tctcctggga    960
atcttggttt ttggcatctg gtttgcctat agccgaggcc actttgacag aacaaagaaa   1020
gggacttcga gtaagaaggt gatttacagc cagcctagtg cccgaagtga aggagaattc   1080
aaacagacct cgtcattcct ggtgtgagcc tggtcggctc accgcctatc atctgcattt   1140
gccttactca ggtgctaccg gactctggcc cctgatgtct gtagtttcac aggatgcctt   1200
atttgtcttc tacaccccac agggccccct acttcttcgg atgtgttttt aataatgtca   1260
gctatgtgcc ccatcctcct tcatgccctc cctccctttc ctaccactgc tgagtggcct   1320
ggaacttgtt taaagtgttt attccccatt tctttgaggg atcaggaagg aatcctgggt   1380
atgccattga cttcccttct aagtagacag caaaaatggc gggggtcgca ggaatctgca   1440
ctcaactgcc cacctggctg gcagggatct ttgaataggt atcttgagct tggttctggg   1500
ctctttcctt gtgtactgac gaccagggcc agctgttcta gagcgggaat tagaggctag   1560
agcggctgaa atggttgttt ggtgatgaca ctggggtcct tccatctctg gggcccactc   1620
tcttctgtct tcccatggga agtgccactg ggatccctct gccctgtcct cctgaataca   1680
agctgactga cattgactgt gtctgtggaa aatgggagct cttgttgtgg agagcatagt   1740
aaattttcag agaacttgaa gccaaaagga tt                                 1772

<210> 1262
<211> 1726
<212> DNA
<213> Homo sapiens

<400> 1262
gtacagtttg tggcgctcag aggataccat atctggctaa ctgtaggcat tcctgaatac     60
tgaccagtac tgtgcaatat cgtatgaagc agaaaacaca acattggcag acaaagcttt    120
ctcagtaaga ccatttgatg tgttctttca tggtcttctt tggcatcctc tctaacatcc    180
accatccacc ctccatcaac aaacaacaag acgttataca ttttctcctt cacatcagca    240
gttagggcat ccaaatgccc tttccaaata ccaaaatcca tttcatattt cttttctttg    300
tgttcatgag ccactttctc agtaaaagtt ggttgaggta tcaaagcagg tttttgtgga    360
actgaattca tatgcttaaa ccactcatta aaggtttcat gggcttccaa ataagctytg    420
atgcacaaat gttcycggat agcattatca tcttcagcag gaagtggact ttccattcct    480
tgttcctcgc actgattawa gatttctgct atagaatcct gaggaatttt cacaaatact    540
tcttttgcag cttcgtgctt ttttgatgcc aagaattttc tcataattgc attgccttgt    600
ttcagtgctt ctgccctctg cgctgggtca aataccaacc agtcaattac atcaattttt    660
aaacgatcct cctcagtagt gccagtatct agggctgggg ccaggtcatg atgactaaat    720
tcaccattat ctttctttcg aatattctca actacagttt ttgttattgt tgcaacatcc    780
aaatctgctt ctttagccaa ctccaggcaa tggtggcgct gttcaaattc tgtaacactt    840
tccaaaaata atgcatactg ggcaacagct aggtcttgag gcaaatgaca ggtataaaat    900
gctataagat ttgtatgttt ctctcttatt aaaagctgta tgtatgtctt taaaacttca    960
atagaaactt cctccttggt ctgtagtccc agagtacgga aaaacaaaat aaggtgagtc   1020
ataaagcgaa gcaggtgtcc aggtagattg tttctgcttt tggaaagcca tttgctaaac   1080
tcatccatca aaccatcaat gtctcccagg ataagaaact tttgaactat atgataatgt   1140
tcttgattct cttccagaac tctctttttg tcagtagctt gaagttcctc aaaaaccttt   1200
tctaacgtcc agtttgctcc cagatattct ctagggagtt cttcagtttc atccagagtt   1260
gctactgatg tctggatctc ctgttctacc agactgtcca ccatcacccg gaagtaggcc   1320
caaactgtgt cttcccaggt gtcacagaca ggaagcagct gcttaagatt cccacttaaa   1380
gctgcataaa ttgctctctc gtatctatta aaaagctcat cttctgccat tctccagcaa   1440
cttattttcc aaatgcgtct atatggattc ccttcaacag gttctaattc tgttcctcca   1500
ttaacattag ggtcatggta cagtttccag ccttcaagtg ttgcagctct ccatgcttga   1560
ccacagcgtt tacagagtcg ttgtgcctct tctgtcattc cagcacggat tagagtaaag   1620
agatatttga gtaatctaac ttcatcttct ctatccagat catcaagggg cattttctgt   1680
cttatgggag catcagggtc caattcagtg acaagcggac gaacac                  1726

<210> 1263
<211> 1074
<212> DNA
<213> Homo sapiens

<400> 1263
gcggccgcct ggcacacact ggtccccttg gcctccaggt agatgctagt ggagggcgcc     60
cgcctggcga cgaggcagag gcaggcagca agagacagcg cgcagatgac gaacagggag    120
tcgctcacca ggacgcggac aagcagcagg gcccagggct gtgcccggcg ccgatgggag    180
agcacagcac acagcacgtt caccagcaga aagagcagcg aggcccccac aaaggcccct    240
cggacagcga gcaagcctcg gctcatctcc ggccgacgct tcaccttggc cttgaacacc    300
acctgggcaa agtagaggtt cataagcgtc aaggtgaaga actgcaggca gacggggcag    360
cagtagagaa gccagaaggg caagggcccc aggcggttgg cgcggggagt atctcggaag    420
tagaaggaga agagggtggt acgcaaggcg gcccagagca gacagagggc caggaacacc    480
gtctgatagc tgagacgctt gtgcccatac agaagcacca gccagagctg ggcatagacg    540
garaagaaga gcagggcata cagggtggtg taggcagctg tcagccccag ggtcacagca    600
ggtggcagcg caggcaccag cccggcagca ggcaccaggc cagacaggtt actctccatg    660
tcagggaggg aggcctgaat cccggagaca gacaaggagg gactgtcggc gggaccaggg    720
aaataaatac ggaggggtgg gaattgcagg gtgcagagag ggagatgggg cgctcaggag    780
gaaagaagtt gtggctgaca ggcccctcct cctcaacaga gagacccttg cccttgggga    840
acacaggcag cctgggcccc aggcccctca ctcaggggca tggaagggca gtctcttttc    900
tccaggacag accggatagg ggttgggggt gtctcctccc tgggcctacc ccagagccaa    960
ggatgggggg atgcagaggc ccaaggagag gactccctgg cctcggtcgt tcatgtcgtc   1020
ctgggtggag ggggagagcc ggctgatacc cgtcgggtca gggcagcggc cgct         1074

<210> 1264
<211> 1958
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1724)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1843)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1850)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1864)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1875)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1907)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1911)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1936)
<223> n equals a,t,g, or c

<400> 1264
tcaccaacca tgcaaatgtg aatgagggca tsgttcccay tkcgatgctg gttgccaacg     60
atcagatggc gctgggcgca atgcgcgcca ttaccgagtc cgggctgcgc gttggtgcgg    120
atatctcggt agtgggatac gacgataccg aagacagctc atgttatatc ccgccgttaa    180
ccaccatcaa acaggatttt cgcctgctgg ggcaaaccag cgtggaccgc ttgctgcaac    240
tctctcaggg ccaggcggtg aagggcaatc agctgttgcc cgtctcactg gtgaaaagaa    300
aaaccaccct ggcgcccaat acgcaaaccg cctctccccg cgcgttggcc gattcattaa    360
tgcagctggc acgacaggtt tcccgactgg aaagcgggca gtgagcgcaa cgcaattaat    420
gtgagttagc tcactcatta ggcaccccag gctttacact ttatgcttcc ggctcgtatg    480
ttgtgtggaa ttgtgagcgg ataacaattt cacacaggaa acagctatga ccatgattac    540
gccaagctct aatacgactc actataggga aagctggtac gcctgcaggt accggtccgg    600
aattcccggg tcgacccacg cgtccgaccg aaacggacac ggactgaatg ttacttttcc    660
tcctctccta agtggaaacg acttccaaac agttgaggaa ggcagtaatg tgaagttggt    720
ttgcaatgtg aaagccaacc cccaggctca aatgatgtgg tacaaaaaca gtagtctcct    780
cgatttagag aaaagccgtc accaaatcca acagacaagt gagtcttttc agctgtcaat    840
caccaaagtc gagaagcctg acaacggaac ctacagttgt attgcaaagt catctctgaa    900
aacggagagc ttggactttc acctgattgt taaagataaa actgtgggtg taccaataga    960
gcccattatt gctgcatgtg ttgtgatctt tctgacattg tgctttggac tgattgctag   1020
aagaaagaaa ataatgaagc tctgcatgaa ggataaagac cctcacagtg aaacagctct   1080
atgagaaagc tgagatgcca tcgaatacag agagagtttt gcatcaggac ctccacaatt   1140
tatgtagtcc catctgtatt tattgctatt attaaattca ctcctgtcac tcctgtttca   1200
ttaatcactt aacagtagtt gktaggacta atttgataca cttgtggaac atttttatgg   1260
aaagagctat taagaatgaa aagtaagatt ttgttaagtc ttctccttga agtatatgtt   1320
aattaattga gatttgttcc aaataggttg gtaatcattt actgtttagt gtgttttttt   1380
tctaggtagg agatacttgg gtctcacaaa ttggtgcaaa gccaaaaaaa aaaaaaaaag   1440
ggcggccgct ctagaggatc caagcttacg tacgcgtgca tgcgacgtca tagctcttct   1500
atagtgtcac ctaaattcaa ttcactggcc gtcgttttac aacgtcgtga ctgggaaaac   1560
cctggcgtta cccaacttaa tcgccttgca gcacatcccc ctttcgccag ctggcgtaat   1620
agcgaagagg cccgcaccga tcgcccttcc caacagttgc gcagcctgaa tggcgaatgg   1680
gacgcgccct gtagcggcgc attaagcgcg gcgggtgtgg tggntacgcg cagcgtgacc   1740
cgctacactt gccagcgccc tagcgcccgt cctttcgctt tcttcccttc ctttcttgcc   1800
acgttcgccc ggctttcccc gtcaagctct aaatcggggg ctncctttan ggttcccatt   1860
tagngcttta ccggnacctt gaccccaaaa aaacttggat taagggngaa nggttcacgt   1920
aaatggggcc cattgnccct gatagaacgg gttttttc                           1958

<210> 1265
<211> 1018
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1016)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1017)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1018)
<223> n equals a,t,g, or c

<400> 1265
gatgctccgg gccgcgctgc ccgcgctcct gctgccgttg ctgggcctcg ccgctgctgc     60
cgtcgcggac tgtccttcrt ctacttggat tcagttccaa gacagttgtt acatttttct    120
ccaagaagcc atcaaagtag aaagcataga ggatgtcaga aatcagtgta ctgaccatgg    180
agcggacatg ataagcatac ataatgaaga agaaaatgct tttatactgg atactttgaa    240
aaagcaatgg aaaggcccag atgatatcct actaggcatg ttttatgaca cagatgatgc    300
gagtttcaag tggtttgata attcaaatat gacatttgat aagtggacag accaagatga    360
tgatgaggat ttagttgaca cctgtgcttt tctgcacatc aagacaggtg aatggaaaaa    420
aggaaattgt gaagtttctt ctgtggaagg aacactatgc aaaacagcta tcccatacaa    480
aaggaaatat ttatcagata accacatttt aatatcagca ttggtgattg ctagcacggt    540
aattttgaca gttttgggag caatcatttg gttcctgtac aaaaaacatt ctgattctcg    600
tttcaccaca gttttttcaa ccgcacccca atcaccttat aatgaagact gtgttttggt    660
agttggagaa gaaaatgaat atcctgttca atttgactaa gtttttggta atcttgcact    720
aagacatcaa caaaatgccc tggcagagat aacttgggaa agattttaat ataaaacttg    780
acattggata ttagagcttt aatggtattc cttattccag taacattttt atgtactcat    840
ctgctgtgaa aagtctttag gttcattaaa aaaacaggtt ttagaaatga tcttagatct    900
aatatactga ttttaagcat cccgtcaaag gcagaatctg tcacttgaat gaaggaaagc    960
ttaaagccca agcagataaa aataaaagcc cagcctattt gtcttgaaaa aaaaannn     1018

<210> 1266
<211> 564
<212> DNA
<213> Homo sapiens

<400> 1266
gtcacccagc ggtggagtga cacggagttc agcggtgcaa tcacggctca ctgcagcctc     60
aacctcacag gctcaagcaa tcctcccatc tcagcctccc gagtagcttg gactacaggc    120
gtgcccttcc atgcccaggt gtcctgatgg caaatttcaa gggccacgcg cttccaggga    180
gtttcttcct gatyattggg ctgtgttgrt cagtgaagta cccgctgaag tactttagcc    240
acacgcggaa gaacagccca ctacattact atcagcgtct cgagatcgtc gaagccgcaa    300
ttaggacttt gttttccgtc aytgggatcc tggcagagca gtttgttccg gatgggcccc    360
amctgcacct ctaccatgag aaccactgga taaagttaat gaatkggcag cacagcacca    420
tgtactawtc tttgcagtct caggaattgt tgacatgctc actatctggt cagccacgtt    480
cccttggggg tggacaract ggttawgggc tgtggcatat tcatgggaag gttttttgtg    540
ggaacggatg ggagaggaag ggag                                           564

<210> 1267
<211> 535
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (407)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (522)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (535)
<223> n equals a,t,g, or c

<400> 1267
gctaccgcag tagccgcctc tgccgccgcg gagcttcccg aacctcttca gccgcccgga     60
gccgctcccg gagcccggcc gtagaggctg caatcgcagc cgggagcccg cagcccgcgc    120
cccgagcccg ccgccgccct tcgagggcgc cccaggccgc gccatggtga aggtgacgtt    180
caactccgct ctggcccaga aggaggccaa gaaggacgag cccaagagcg gcgaggaggc    240
gctcatcatc ccccccgacg ccgtcgcggt ggactgcaag gacccagatg atgtggtacc    300
agttggccaa agaagagcct ggtgttggtg catgtgcttt ggactagcat ttatgcttgc    360
aggtgttatt ctaggaggag catacttgta caaatatttt gcacttnaac cagatgacgt    420
gtactactgt ggaataaagt acatcaaaga tgatgtcatc ttaaatgagc cctctgcaga    480
tgccccagct gctctctacc agacaattga agaaaatatt anaatctttg aagan         535

<210> 1268
<211> 994
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (221)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (948)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (955)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (966)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (977)
<223> n equals a,t,g, or c

<400> 1268
gggacggttt gtgaccccct tagccgaccc tactcctcac tggccgggac aactggtctt     60
atcacggagg ctggggccag gcagcccttc ggttcgggtg ggcccatgga ccccagtcca    120
acgccgaggg aataggacca tccaaaagcg gaaccttcgc ctcagaaaaa gggtgcggga    180
cccctcctca ccgtgcggtc acgcgtggac cctgccagca nccaggccat ggagctctct    240
gatgtcaccc tcattgaggg tgtgggtaat gaggtgatgg tggtggcagg tgtggtggtg    300
ctgattctag ccttggtcct agcttggctc tctacctacg tagcagacag cggtagcaac    360
cagctcctgg gcgctattgt gtcagcaggc gacacatccg tcctccacct ggggcatgtg    420
gaccacctgg tggcaggcca aggcaacccc gagccaactg aactccccca tccatcagag    480
gacaagcagg tgcaggcagc agcagtccag aggcccccct gagatctgag gatagcacct    540
gcctccctcc cagccctggc ctcatcactg tgcggctcaa attcctcaat gataccgagg    600
agctggctgt ggctaggcca gaggataccg tgggtgccct gaagagcaaa tacttccctg    660
gacaagaaag ccagatgaaa ctgatctacc agggccgcct gctacaagac ccagcccgca    720
cactgcgttc tctgaacatt accgacaact gtgtgattca ctgccaccgc tcacccccag    780
ggtcagctgt tccaggcccc tcagcctcct tggscccctc ggccactgag ccaccmagct    840
tggtgtcaat gtggggcarc ctcatggtgc tgtmtttgtg gtgctgttgg gtgtrgtctg    900
gtacttycga aatcaattac cgccaattct tcaaagcaac tgccaatntc tcccnggtgg    960
gaaatnaccg tcttctnaag cttcctaagt aatt                                994

<210> 1269
<211> 2024
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1921)
<223> n equals a,t,g, or c

<400> 1269
accttgtcag gttgtttgtc cagaacttaa aaagccccaa tgttacccat tctccaagtc     60
ytcttcagtg cagggcatsc agtagggcag ccagcacttg gggctctggt ttcctggtgg    120
actggccats aacaggcggg caagtgcccc acagatgttg tcacggwcac gatcatgtcg    180
ctcccgcgcc agragggraa aaaggagccc cagcagcttg gggaagtgtt cctgggcagg    240
gtggccccca tgctctgcca gcacgcccat cccgaagatg gcattgcttc gcacctcggg    300
gtctgcctct tgggcggtgc tcaacagcac agggagcagc cgagacacaa actgggctga    360
ggcagcaccc aggccctgaa tagtctctgc caaggtcccc actgcaaagg acttctctgc    420
cactgtgcag ccctgttttg tcttgcacac caataatggc aggaaaccgg caaagaatgg    480
ggcaaaggag tctcccccag ccgcggctgc cagggcaggg atggcctctc cagcgtgctc    540
cagcaacatg gcgtcgtatt cagcctgatc atcatcttcc tcttcctcct cctcgtcagt    600
atcctgacag gctgtcttcc tctgcagcac agccttgagc acgccacaga gctcagcgag    660
gcgcccaggg ggcttcagtg tgagggtccc acagctgcgg agcacccctg tcagggcctc    720
cagcacggcc atcaccacct ggcgttcccg ctccctgttc actgcctgca tgtaggatgg    780
cacgactcgg gccagggcag cctgcaaagc agcagtgttg ggttccgagg ggcagctttg    840
acaggccttg tgcagtgcac agcaaaactg acccagagcc tcatgggctg ccttccgcac    900
attcaggtga gggcactcca gcagtttaaa tacttcttca aagacacttt ccatgtatgg    960
aaggaaggcc acactggtgt tcacagagat ctcccccacg gcagcacagg tgtcttcctt   1020
ctcatcgaag aaggcattct ccacgctgta ccctgagatc tytgagtcat cctcttcttc   1080
cacatcctca tccatgagct cctcctcttc ttccccatca ctctcatcgt caaacagaag   1140
gaaggagctg ctcccgtcat actgaggcac aatgccctcg gtggaacgca gtgacagcag   1200
catgagcgtg gtgatctgtt ccaagtgggg cgccaggccc tcacccatca gacccgataa   1260
ggctgcaaat aggctgtacg tgcagcgccg caagtcagcg tcgtctacct ggtcgcagag   1320
gcccagaccc agctggcagc attcctcagc cagcggcctc atgggctccc ccactgctcg   1380
tgccagcacc cccagtgtct ccaggctctg gatctgcaca ggctgaaggt cctcacggcc   1440
tgttaacagg aattcccgca ggtgctccat gatggcaggg aagtagggca gcagcgagac   1500
ctgggcagcc gtagcaatgg ctcccagggc gctcacagcc agctccttgg cccggggact   1560
gctggggttc ctcagaagct gcagcatgca ttccataagc tccggaaggt agggctgcac   1620
cttgggccct aggttctcca caaaattctc cagggcatag caggccttgg ctaggtggtg   1680
tgtgtgtcca agaggcaccg acttcaagta ggcgaggagc agtggcatta cctcccttga   1740
atagctgctg atatggggct gtaggttttc tgagaactgg cccagggcaa acagcgcagc   1800
attgcgtaca acttgcgagg ggtcctccag gcccttgcac acaatctgca gcagtggggg   1860
cagcagtctc tgcctgatgt ggtcgccagc tccgtcagac agcacggcca gcaccaggag   1920
ntcagctttg cgctggtatg ggctcctctc cgcaaagcct cttccaacat gggcatcagc   1980
tggggacaga gcttctcggg gggggttaaa aaacaaaaaa aaaa                    2024

<210> 1270
<211> 3155
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3151)
<223> n equals a,t,g, or c

<400> 1270
ggcacaggga aagaagctgt ctccatcttg tctgtatccg ctgctcttgt gacgttgtgg     60
agatggggag cgtcctgggg ctgtgctcca tggcgagctg gataccatgt ttgtgtggaa    120
gtgccccgtg tttgctatgc cgatgctgtc ctagtggaaa caactccact gtaactagat    180
tgatctatgc acttttcttg cttgttggag tatgtgtagc ttgtgtaatg ttgataccag    240
gaatggaaga acaactgaat aagattcctg gattttgtga gaatgagaaa ggtgttgtcc    300
cttgtaacat tttggttggc tataaagctg tatatcgttt gtgctttggt ttggctatgt    360
tctatcttct tctctcttta ctaatgatca aagtgaagag tagcagtgat cctagagctg    420
cagtgcacaa tggattttgg ttctttaaat ttgctgcagc aattgcaatt attattgggg    480
cattcttcat tccagaagga acttttacaa ctgtgtggtt ttatgtaggc atggcaggtg    540
ccttttgttt catcctcata caactagtct tacttattga ttttgcacat tcatggaatg    600
aatcgtgggt tgaaaaaatg gaagaaggga actcgagatg ttggtatgca gccttgttat    660
cagctacagc tctgaattat ctgctgtctt tagttgctat cgtcctgttc tttgtctact    720
acactcatcc agccagttgt tcagaaaaca aggcgttcat cagtgtcaac atgctcctct    780
gcgttggtgc ttctgtaatg tctatactgc caaaaatcca agaatcacaa ccaagatctg    840
gtttgttaca gtcttcagta attacagtct acacaatgta tttgacatgg tcagctatga    900
ccaatgaacc agaaacaaat tgcaacccaa gtctactaag cataattggc tacaatacaa    960
caagcactgt cccaaaggaa gggcagtcag tccagtggtg gcatgctcaa ggaattatag   1020
gactaattct ctttttgttg tgtgtatttt attccagcat ccgtacttca aacaatagtc   1080
aggttaataa actgactcta acaagtgatg aatctacatt aatagaagat ggtggagcta   1140
gaagtgatgg atcactggag gatggggacg atgttcaccg agctgtagat aatgaaaggg   1200
atggtgtcac ttacagttat tccttctttc acttcatgct tttcctggct tcactttata   1260
tcatgatgac ccttaccaac tggtacaggt atgaaccctc tcgtgagatg aaaagtcagt   1320
ggacagctgt ctgggtgaaa atctcttcca gttggattgg catcgtgctg tatgtttgga   1380
cactcgtggc accacttgtt cttacaaatc gtgattttga ctgagtgaga cttctagcat   1440
gaaagtccca ctttgattat tgcttatttg aaaacagtat tcccaacttt tgtaaagttg   1500
tgtatgtttt tgcttcccat gtaacttctc cagtgttctg gcatgaatta gattttactg   1560
cttgtcattt tgttattttc ttaccaagtg cattgatatg tgaagtagaa tgaattgcag   1620
aggaaagttt tatgaatatg gtgatgagtt agtaaaagtg gccaytattg ggcttattct   1680
ctgctctata gttgtgaaat gaagagtraa aacaaatttg tttgactatt ttaaaattat   1740
attagacctt aagctgtttt agcaagcatt aaagcaaatg tatggctgcc ttttgaaata   1800
tttgatgtgt tgcctggcag gatactgcaa agaacatggt ttattttaaa atttataaac   1860
aagtcactta aatgccagtt gtctgaaaaa tcttataagg ttttaccctt gatacggaat   1920
ttacacaggt agggagtgtt tagtggacaa tagtgtaggt tatggatgga ggtgtcggta   1980
ctaaattgaa taacgagtaa ataatcttac ttgggtagag atggcctttg ccaacaaagt   2040
gaactgtttt ggttgtttta aactcatgaa gtatgggttc agtggaaatg tttggaactc   2100
tgaaggattt agacaaggtt ttgaaaagga taatcatggg ttagaaggaa gtgtttgaaa   2160
gtcactttga aagttagttt tgggccagca cggtagctca cccttgtaat cccagcactt   2220
tgggaggctg aggtgggtag attacttgag cccaggaatt caagaccagc ctgggcaaca   2280
tggtgaaacc ctgtttctat aaaaaataat ctgggctttg tagcatatgc ctgtggtccc   2340
agctactgag gaggctgagg tgggaggatt gcttgagccc aggaggcaga ggttgcagtg   2400
agccaaggtc acgtcactgc actctagcct gggcaacaga gtaagacaaa aaaatatata   2460
tatattgaaa atcaaaggag gcaaaatttt gacagggaag gaagtaactg caaaacacta   2520
ggctttagta ggtacttata taaaatctag tccagttctc tcatttaaaa aaatgaagac   2580
actgaagtac agacttaaat agctcagata gctaattagg aaatttcaag ttggccaata   2640
atagcattct ctctgacatt taaaaataat ttctattcaa aatacatgca taattgattt   2700
tacacctcat tactggtgga taatttatgt gatgtggatt gctggtgtcc agcatgaccc   2760
ataaacaggt cagaagaatg atggaatgtt ttagaataaa ctcctgctta tagtatacta   2820
cacagttcaa aagatgttta aaatgctttt gtatttactg ccatgtaatt gaaatatata   2880
gattattgta acctttcaac ctgaaaatca agcagtatga gagtttagtt atttgtatgt   2940
gtcactagtg tctaatgaag cttttaaaat ctacaatttc ttctttaaaa atatttatta   3000
atgtgaatgg aatataacaa ttcagcttaa ttccccaacc ttattctgtg tgtagacatt   3060
gtattccaca attttgaatg gctgtgtttt acctctaaat aaatgaattc agagaaaaaa   3120
aaaaaaaaaa aaaaaaaaaa aaaagggggg ncccc                              3155

<210> 1271
<211> 589
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (429)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (565)
<223> n equals a,t,g, or c

<400> 1271
accaactcaa aaggtcacct atcagtgtgc catgtgccac ctcctggagc acacacatgt     60
gcacacacat acactcacac gtgtgtkcag gtgcacacct cccccagagg ctgcagccaa    120
gacgggcatc ccacatcaga gggatgaatg gcaggtctgt cccgccagct gtgtgctctc    180
tcccacccga agaaagcagc agagactcag acggcggagc tggaggagcc cacgcagtct    240
gttcccggca cccggtgcgt gtraagggac ttgarggcak cgagatggaa tcagcaagag    300
aaaacatcga ccttcaacct ggaagctccg accccaggag ccagcccatc aacctgaacc    360
attacgccac caagaagagc gtggcgkaga gcatgctgga cgtggccctg ttcatgtcca    420
acgccatgng gctgaaggcg gtgctggagc agggaccatc ctctcactac tacaccaccc    480
tggtcaccct catcagcctc tctctgctcc tgcagttggt tcatcggtgt ctgctcgtgg    540
tcattgcacg gctgaactgr atgangtaga aaagcatggc gamtcaacc                589

<210> 1272
<211> 2171
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (17)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (24)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (33)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2093)
<223> n equals a,t,g, or c

<400> 1272
ggatancaat tttcacncag naancagcta tgnccatgat tacgccaagc tttaatacga     60
ctcactatag ggaaagctgg tacgcctgca ggtaccggtc cggaattccc gggtcgaccc    120
acgcgtccgc cagcaccaca gtgccaggcc ttagtgagga atctaccacc ttctacagca    180
gcccaggctc aactgaaacc acagcgtttt ctcacagcaa cacaatgtcc attcatagtc    240
aacaatctac acccttccct gacagcccag gcttcactca cacagtgtta cctgccaccc    300
tcacaaccac agacattggt caggaatcaa cagccttcca cagcagctca gacgcaactg    360
gaacaacacc cttacctgcc cgctccacag cctcagacct tgttggagaa cctacaactt    420
tctacatcag cccatcccct acttacacaa cactctttcc tgcgagttcc agcacatcag    480
gcctcactga ggaatctacc accttccaca ccagtccaag cttcacttct acaattgtgt    540
ctactgaaag cctggaaacc ttagcaccag ggttgtgcca ggaaggacaa atttggaatg    600
gaaaacaatg cgtctgtccc caaggctacg ttggttacca gtgcttgtcc cctctggaat    660
ccttccctgt agaaaccccg gaaaaactca acgccacttt aggtatgaca gtgaaagtga    720
cttacagaaa tttcacagaa aagatgaatg acgcatcctc ccaggaatac cagaacttca    780
gtaccctctt caagaatcgg atggatgtcg ttttgaaggg cgacaatctt cctcagtata    840
gaggggtgaa cattcggaga ttgctcaacg gtagcatcgt ggtcaagaac gatgtcatcc    900
tggaggcaga ctacacttta gagtatgagg aactgtttga aaacctggca gagattgtaa    960
aggccaagat tatgaatgaa actagaacaa ctcttcttga tcctgattcc tgcagaaagg   1020
ccatactgtg ctatagtgaa gaggacactt tcgtggattc atcggtgact ccgggctttg   1080
acttccagga gcaatgcacc cagaaggctg ccgaaggata tacccagttc tactatgtgg   1140
atgtcttgga tgggaagctg gcctgtgtga acaagtgcac caaaggaacg aagtcgcaaa   1200
tgaactgtaa cctgggcaca tgtcagctgc aacgcagtgg cccccgctgc ctgtgcccaa   1260
atacgaacac acactggtac tggggagaga cctgtgaatt caacatcgcc aagagcctcg   1320
tgtatgggat cgtgggggct gtgatggcgg tgctgctgct cgcattgatc atcctaatca   1380
tcttattcag cctatcccag agaaaacggc acagggaaca gtatgatgtg cctcaagagt   1440
ggcgaaagga aggcacccct ggcatcttcc agaagacggc catctgggaa gaccagaatc   1500
tgagggagag cagattcggc cttgagaacg cctacaacaa cttccggccc accctggaga   1560
ctgttgactc tggcacagag ctccacatcc agaggccgga gatggtagca tccactgtgt   1620
gagccaacgg gggcctccca ccctcatcta gctctgttca ggagagctgc aaacacagag   1680
cccaccacaa gcctccgggg cgggtcaaga ggagaccgaa gtcaggccct gaagccggtc   1740
ctgctctgag ctgacagact tggccagtcc cctgcctgtg ctcctgctgg ggaaggctgg   1800
gggctgtaag cctctccatc cgggagcttc cagactccca gaagcctcgg cacccctgtc   1860
tcctcctggg tggctcccca ctctggaatt tccctaccaa taaaagcaaa tctgaaagct   1920
caaaaaaaaa aaaaaagggc ggccgctcta gaggatccaa gcttacgtac gcgtgcatgc   1980
gacgtcatag ctcttctata gtgtcaccta aattcaattc actggccgtc gttttacaac   2040
gtctgactgg gaaaaccctg gcgttaccca acttaatcgc cttgcagcac atnccccttt   2100
ygccagctgc gtaatagcra agaggsccgs accgatcgcc cttccaacag ttgcgcagcc   2160
tgaatggcga a                                                        2171

<210> 1273
<211> 1892
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1834)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1836)
<223> n equals a,t,g, or c

<400> 1273
ggagccgccg cgcgcgcgcc gcgcactgca gccccaggcc ccggcccccc acccacgtct     60
gcgttgctgc cccgcctggg ccrggcccca aaggcaagga caaagcagct gtcagggaac    120
ctccgccgga gtcgaattta cgtgcagctg ccggcaacca caggttccaa gatggtttgc    180
gggggcttcg cgtgttccaa gaactgcctg tgcgccctca acctgcttta caccttggtt    240
agtctgctgc taattggaat tgctgcgtgg ggcattggct tcgggctgat ttccagtctc    300
cgagtggtcg gcgtggtcat tgcagtgggc atcttcttgt tcctgattgc tttagtgggt    360
ctgattggag ctgtaaaaca tcatcaggtg ttgctattyt tttatatgat tattctgtta    420
cttgtattta ttgttcagtt ttctgtatct tgcgcttgtt tagccctgaa ccaggagcaa    480
cagggtcagc ttctggaggt tggttggaac aatacggcaa gtgctcgaaa tgacatccag    540
agaaatctaa actgctgtgg gttccgaagt gttaacccaa atgacacctg tctggctagc    600
tgtgttaaaa gtgaccactc gtgctcgcca tgtgctccaa tcataggaga atatgctgga    660
gaggttttga gatttgttgg tggcattggc ctgttcttca gttttacaga gatcctgggt    720
gtttggctga cctacagata caggaaccag aaagaccccc gcgcraatcc tagtgcattc    780
ctttgatgag aaaacaagga agatttcctt tcgtattatg atcttgttca ctttctgtaa    840
ttttctgtta agctccattt gccagtttaa ggaaggaaac actatctgga aaagtacctt    900
attgatagtg gaattatata tttttactct atgtttctct acatgttttt ttctttccgt    960
tgctgaaaaa tatttgaaac ttgtggtctc tgaagctcgg tggcacctgg aatttactgt   1020
attcattgtc gggcactgtc cactgtggcc tttcttagca tttttacctg cagaaaaact   1080
ttgtatggta ccactgtgtt ggttatatgg tgaatctgaa cgtacatctc actggtataa   1140
ttatatgtag cactgtgctg tgtagatagt tcctactgga aaaagagtgg aaatttatta   1200
aaatcagaaa gtatgagatc ctgttatgtt aagggaaatc caaattccca attttttttg   1260
gtctttttag gaaagatgtg ttgtggtaaa aagtgttagt ataaaaatga taatttactt   1320
gtagtctttt atgattacac caatgtattc tagaaatagt tatgtcttag gaaattgtgg   1380
tttaattttt gacttttaca ggtaagtgca aaggagaagt ggtttcatga aatgttctaa   1440
tgtataataa catttacctt cagcctccat cagaatggaa cgagttttga gtaatcagga   1500
agtatatcta tatgatcttg atattgtttt ataataattt gaagtctaaa agactgcatt   1560
tttaaacaag ttagtattaa tgcgttggcc cacgtagcaa aaagatattt gattatctta   1620
aaaattgtta aataccgttt tcatgaaagt tctcagtatt gtaacagcaa cttgtcaaac   1680
ctaagcatat ttgaatatga tctcccataa tttgaaattg aaatcgtatt gtgtggctct   1740
gtatattctg ttaaaaaatt aaaggacaga aacctttctt tgtgtatgca tgtttgaatt   1800
aaaagaaagt aatggaagaa ttgaaaaaaa aaananaaaa atgaccctcg agggggggcc   1860
cgtacccaat tcgccctata gtgagtcgta tg                                 1892

<210> 1274
<211> 1996
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1975)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1980)
<223> n equals a,t,g, or c

<400> 1274
ggtcgaccca cgcgtccggg tggctccaga gatggcagtg agcgagagga gggggctcgg     60
ccgcgggagc cccgcggagt gggggcagcg gctacttctg gtgctgctgt tgggtggctg    120
ctccgggcgc atccaccggc tggcgctgac gggggagaag cgagcggaca tccagctgaa    180
cagcttcggt ttctacacca atggctctct ggaggtggag ttgagcgtcc tgcggctggg    240
cctccgggag gcagaagaga agtccctgct ggtggggttc agtctcagcc gggttcggtc    300
tggcagagtt cgctcctatt caacccggga tttccaggac tgccctctcc agaaaaacag    360
tagcagtttc ctggtcctgt tcctcatcaa caccaaggat ctgcaggtcc aggtgcggaa    420
gtatggagag cagaagacgt tgtttatctt tcccgggctc ctcccggaag caccctccaa    480
accagggctc ccgaagccac aggccacagt cccccgcaag gtggatggcg gagggacctc    540
tgcagccagc aagcccaagt caacacccgc agtgattcag ggtcctagtg ggaaggacaa    600
ggacctggtg ttgggcctga gccacctcaa caactcctac aacttcagtt tccacgtggt    660
gatcggctct caggcggaag aaggccagta cagcctgaac ttccacaact gcaacaattc    720
agtgccagga aaggagcatc cattcgacat cacggtgatg atccgggaga agaaccccga    780
tggcttcctg tcggcagcgg agatgcccct tttcaagctc tacatggtca tgtccgcctg    840
cttcctggcc gctggcatct tctgggtgtc catcctctgc aggaacacgt acagcgtctt    900
caagatccac tggctcatgg cggccttggc cttcaccaag agcatctctc tcctcttcca    960
cagcatcaac tactacttca tcaacagcca gggccacccc atcgaaggcc ttgccgtcat   1020
gtactacatc gcacacctgc tgaagggcgc cctcctcttc atcaccatcg ccctgattgg   1080
ctcaggctgg gccttcatca agtacgtcct gtcggataag gagaagaagg tctttgggat   1140
cgtgatcccc atgcaggtcc tggccaacgt ggcctacatc atcatcgagt cccgcgagga   1200
aggcgccagc gactacgtgc tgtggaagga gattttgttc ctggtggacc tcatctgctg   1260
tggtgccatc ctgttccccg tagtctggtc catccggcat ctccaggatg cgtctggcac   1320
agacgggaag gtggcagtga acctggccaa gctgaagctg ttccggcatt actatgtcat   1380
ggtcatctgc tacgtctact tcacccgcat catcgccatc ctgctgcagg tggctgtgcc   1440
ctttcagtgg cagtggctgt accagctctt ggtggagggc tccaccctgg ccttcttcgt   1500
gctcacgggc tacaagttcc agcccacagg gaacaacccg tacctgcagc tgccccagga   1560
ggacgaggag gatgttcaga tggagcaagt aatgacggac tctgggttcc gggaaggcct   1620
ctccaaagtc aacaaaacag ccagcgggcg ggaactgtta tgatcacctc cacatctcag   1680
accaaagggt cgtcctcccc cagcatttct cactcctgcc cttcttccac agcgtatgtg   1740
gggaggtgga gggggtccat gtggaccagg cgcccagctc cccgggaccc cggttcccgg   1800
acaagcccat ttggaagaag agtcccttcc tccccccaaa tattgggcag ccctgtcctt   1860
accccgggac cacccctccc ttccagctat gtgtacaata atgaccaatc tgtttggcta   1920
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaggggg gccgntctan   1980
aggatccctc gagggg                                                   1996

<210> 1275
<211> 1780
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1779)
<223> n equals a,t,g, or c

<400> 1275
cccaaaggca tccaagagac cgaggagatg ctgaaggtgg gggccaccct cacaggggtt     60
ggcgaactgg tcctggacaa caactctgtc cgcctgcagc cgcccaaaca aggcatgcag    120
tactatctaa gcagccagga cttcgacagc ctgctgcaga ggcaggagtc gagcgtcagg    180
ctctggaarg tgctggcgct ggtttttggc tttgccacat gtgccaccct cttcttcatt    240
ctccggaagc agtatctgca gcggcaggag cgcctgcgcc tcaagcagat gcaggaggag    300
ttccaggagc atgargccca gctgctgagc cgagccaagc ctgaggacar ggagagtctg    360
aagagcgcct gtgtagtgtg tctgagcagc ttcaagtcct gcgtctttct ggagtgtggg    420
cacgtttgtt cctgcaccga gtgctaccgc gccttgccag agcccaagaa gtgccctatc    480
tgcagacagg cgatcacccg ggtgataccc ctgtacaaca gctaatagtt tggaagccgc    540
acagcttgac ctggaagcac ccctgccccc ttttcaggga tttttatctc gaggcctttg    600
gaggagcagt ggtgggggta gctgtcacct ccaggtatga ttgagggagg aattgggtag    660
aaactctcca gacccatgcc tccaatggca ggatgctgcc tttcccacct gagaggggac    720
cctgtccatg tgcagcctca tcagagcctc accctgggag gatgccgtgg cgtctcctcc    780
caggagccag atcagtgcga gtgtgactga aaatgcctca tcacttaagc accaaagcca    840
gtgatcagca gctcttctgt tcctgtgtct tctgtttttt tctggtgaat cgttgcttgc    900
tgtggacttg gtggaggact caggggagga aaggctgggc cccgagtaca acggatgcct    960
tgggtgctgc ctccgaagag actctgccgc agcttttctt ctttttcctc atgccccggk   1020
waacagtctt tcttcagaat tgtcaggctg ggcaggtcaa cttgtgttcc tttcccctca   1080
cctgcttgcc tccttaacgc ctgcacgtgt gtgtagagga caaaagaaag tgaagtcagc   1140
acatccgctt ctgcccagat ggtcggggcc ccgggcaaca gattgaagag agatcatgtg   1200
aagggcagtt ggtcaggcag gcctcctggt ttcgccactg gccctgattt gaactcctgc   1260
cacttgggag agctcggggt ggtccctggt tttccctcct ggagaatgag gcgcagaggc   1320
ctcgcctcct gaaggacgca gtgtggatgc cactggccta gtgtcctggc ctcacagctt   1380
ccttgcaagg ctgtcacaag gaaaagcagc cggctggcac cctgagcata tgccctcttg   1440
gggctccctc atccagcccg tcgcagcttt gacatcttgg tgtactcatg tcgcttctcc   1500
ttgtgttacc ccctcccagt attaccattt gcccctcacc tgcccttggt gagcctttta   1560
gtgcaagaca gatggggctg ttttccccca cctctgagta gttggaggtc acatacacag   1620
ctcttttttt attgcccttt tctgcctctg aatgttcatc tctcgtcctc ctttgtgcag   1680
gcgaggaagg ggtgcctcag gggccgacac tagtatgatg cagtgtccag tgtgaacagc   1740
agaaattaaa catgttgcaa ccaaaaaaaa aaaaaagana                         1780

<210> 1276
<211> 1377
<212> DNA
<213> Homo sapiens

<400> 1276
ggcacgagaa aaccttgagg tgattcatct tccaggctct ccttccatca agtctctcct     60
ccctagcgct ctgggtcctt aatggcagca gccgccgcta ccaagatcct tctgtgcctc    120
ccgcttctgc tcctgctgtc cggctggtcc cgggctgggc gagccgaccc tcactctctt    180
tgctatgaca tcaccgtcat ccctaagttc agacctggac cacggtggtg tgcggttcaa    240
ggccaggtgg atgaaaagac ttttcttcac tatgactgtg gcaacaagac agtcacacct    300
gtcagtcccc tggggaagaa actaaatgtc acaacggcct ggaaagcaca gaacccagta    360
ctgagagagg tggtggacat acttacagag caactgcgtg acattcagct ggagaattac    420
acacccaagg aacccctcac cctgcaggcc aggatgtctt gtgagcagaa agctgaagga    480
cacagcagtg gatcttggca gttcagtttc gatgggcaga tcttcctcct ctttgactca    540
gagaagagaa tgtggacaac ggttcatcct ggagccagaa agatgaaaga aaagtgggag    600
aatgacaagg ttgtggccat gtccttccat tacttctcaa tgggagactg tataggatgg    660
cttgaggact tcttgatggg catggacagc accctggagc caagtgcagg agcaccactc    720
gccatgtcct caggcacaac ccaactcagg gccacagcca ccaccctcat cctttgctgc    780
ctcctcatca tcctcccctg cttcatcctc cctggcatct gaggagagtc ctttagagtg    840
acaggttaaa gctgatacca aaaggctcct gtgagcacgg tcttgatcaa actcgccctt    900
ctgtctggcc agctgcccac gacctacggt gtatgtccag tggcctccag cagatcatga    960
tgacatcatg gacccaatag ctcattcact gccttgattc cttttgccaa caattttacc   1020
agcagttata cctaacatat tatgcaattt tctcttggtg ctacctgatg gaattcctgc   1080
acttaaagtt ctggctgact aaacaagata tatcattttc tttcttctct ttttgtttgg   1140
aaaatcaagt acttctttga atgatgatct ctttcttgca aatgatattg tcagtaaaat   1200
aatcacgtta gacttcagac ctctggggat tctttccgtg tcctgaaaga gaatttttaa   1260
attatttaat aagaaaaaat ttatattaat gattgtttcc tttagtaatt tattgttctg   1320
tactgatatt taaataaaga gttctatttc ccaaaaaaaa aaaaaaaaaa aaaaaaa      1377

<210> 1277
<211> 2158
<212> DNA
<213> Homo sapiens

<400> 1277
gcaaaaagga ccgcccattg aagatgccat tgcttcttcc gatgttcttg agactgcttc     60
taaatctgct aatccacccc acacgattca agcatcagaa gagcagagtt caaccccagc    120
accggtgaaa aagtctggca agctgaggca gcaaatagat gtgaaggcgg aactggagaa    180
gcggcaagga gggaagcagc tactcaactt agtggtcatt ggtcatgttg atgctgggaa    240
aagtactctg atgggccata tgctttatct tctgggtaat ataaacaaaa gaactatgca    300
taagtatgaa caggagtcta aaaaggctgg caaagcttcg tttgcatatg catgggtctt    360
ggatgaaact ggcgaagaaa gggaaagggg agtaaccatg gatgttggta tgacaaagtt    420
tgaaaccaca accaaagtta ttacattaat ggatgctcca ggccataagg acttcattcc    480
aaatatgatt acaggagcag cccaggcgga tgtagctgtt ttagttgtag atgccagcag    540
gggagagttt gaagctggat ttgagactgg aggacaaaca cgagagcatg gactcttggt    600
ccgttctctg ggagtgacgc agcttgcagt tgcagttaat aaaatggatc aggttaattg    660
gcaacaagaa aggtttcaag agattactgg aaaacttggg cactttctta agcaagcagg    720
ttttaaggag agtgatgtag gttttattcc tacaagtggt ctcagtggtg aaaatctaat    780
cacaagatct cagtcaagtg aactcacaaa atggtataaa ggactatgtt tattagaaca    840
aattgattcc tttaagcctc cccagcgatc tattgacaaa ccttttagat tatgtgtgtc    900
cgatgttttc aaagatcaag gatctggatt ttgcataact ggtaaaatag aagctggtta    960
tatccaaact ggtgaccgac tactggcaat gcctcctaat gaaacttgta ccgtgaaagg   1020
aatcactctg catgatgaac ctgtcgactg ggcggcagca ggcgatcatg ttagtcttac   1080
tttggttggg atggatatca tcaaaatcaa tgttggctgc atattttgtg gccccaaagt   1140
acccattaaa gcttgcactc gtttcagagc ccgaatcctc atctttaata ttgaaattcc   1200
tatcactaaa ggatttcctg tgctgttaca ctaccaaact gtcagtgaac ccgccgttat   1260
taaacgattg attagtgtct taaacaaaag cacgggtgaa gtcacaaaga aaaagcctaa   1320
gtttttgact aaaggccaga atgcattggt agagctacag acacaaagac caatagctct   1380
tgagctatat aaagacttta aagagctggg gaggttcatg ctacgttacg gtggttctac   1440
aatagctgct ggtgttgtca ctgagataaa agaatgatgg gtcagaattt ctaccacgtt   1500
tctggataca gtgaaatagc taacctctgt ttcaagaatg cagttattaa gtcaaaggaa   1560
caatgtgcaa ttgatatgtt tttagatgag agagaaaaat taaagctaaa attagctgca   1620
aagaagtatt aataatcacc tctgcaaaaa ttctaagttg ccaactggca aagaaagtct   1680
aatgttaaaa acaactttgc ctttgaaacg ttaataaatg gatttacttt gctaagattt   1740
atggcaagtg tcaaaaatag tatctgaaga tactgaatca tcatgaaatg aactctactt   1800
ctggccaaag cacaatgtat ttgcagtttt ctcttttgat tcaattatac tgcacatgtt   1860
ttaaggaaaa gtaacttaat tgggtttttc aggcagttga tatttgacct aagctttttt   1920
tttttttttt tttccagtta atgctaagaa aagatttggg gaaggttata ataaaagtat   1980
tttgtggtga ccataagaat gtccctcccc aaacaagtaa acttgtgaaa gtttaatttg   2040
gaattagtgg aagctgttcc tttgaaagcc aagatattat ttaagttgta aagccagcta   2100
ataaaatgcc ttagtttgag cataaaaaaa aaaaaaaaaa aaaaaaaaaa aactcgag     2158

<210> 1278
<211> 847
<212> DNA
<213> Homo sapiens

<400> 1278
cgctgggccg gtgggcgggg gccggcaggt gctccgcagc cgtctgtgcc acccagagcc     60
ggcgggccgc taggtccccg gagaccctgc tatggtgcgt gcgggcgccg tgggggctca    120
tctccccgcg tccggcttgg atatcttcgg ggacctgaag aagatgaaca agcgccagct    180
ctattaccag gttttaaact tcgccatgat cgtgtcttct gcactcatga tatggaaagg    240
cttgatcgtg ctcacaggca gtgagagccc catcgtggtg gtgctgagtg gcagtatgga    300
gccggccttt cacagaggag acctcctgtt cctcacaaat ttccgggaag acccaatcag    360
agctggtgaa atagttgttt ttaaagttga aggacgagac attccaatag ttcacagagt    420
aatcaaagtt catgaaaaag ataatggaga catcaaattt ctgactaaag gagataataa    480
tgaagttgat gatagaggct tgtacaaaga aggccagaac tggctggaaa agaaggacgt    540
ggtgggaaga gcaagagggt ttttaccata tgttggtatg gtcaccataa taatgaatga    600
ctatccaaaa ttcaagtatg ctcttttggc tgtaatgggt gcatatgtgt tactaaaacg    660
tgaatcctaa aatgagaagc agttcctggg accagattga aatgaattct gttgaaaaag    720
agaaaaacta atatatttga gatgttccat tttctgtata aaagggaaca gtgtggagat    780
gtttttgtct tgtccaaata aaagattcac cagtaaaaaa aaaaaaaaaa aaaaaaaaaa    840
aaaaaaa                                                              847

<210> 1279
<211> 2246
<212> DNA
<213> Homo sapiens

<400> 1279
gcggccgcag ctccttcacc agcttggtgg tgggcgtgtt cgtggtctac gtggtgcaca     60
cctgctgggt catgtacggc atcgtctaca cccgcccgtg ctccggcgac gccaactgca    120
tccagcccta cctggcgcgg cggcccaagc tgcagctgag cgtgtacacc acgacgaggt    180
cccacctggg tgctgagaac aacatcgacc tggtcttgaa tgtggaagac tttgatgtgg    240
agtccaaatt tgaaaggaca gttaatgttt ctgtaccaaa gaaaacgaga aacaatggga    300
cgctgtatgc ctacatcttc ctccatcacg ctggggtcct gccgtggcac gacgggaagc    360
aggtgcacct ggtcagtcct ctgaccacct acatggtccc caagccagaa gaaatcaacc    420
tgctcaccgg ggagtctgat acacagcaga tcgaggcgga gaagaagccg acgagtgccc    480
tggatgagcc agtgtcccac tggcgaccgc ggctggcgct gaacgtgatg gcggacaact    540
ttgtctttga cgggtcctcc ctgcctgccg atgtgcatcg gtacatgaag atgatccagc    600
tggggaaaac cgtgcattac ctgcccatcc tgttcatcga ccagctcagc aaccgcgtga    660
aggacctgat ggtcataaac cgctccacca ccgagctgcc cctcaccgtg tcctacgaca    720
aggtctcact ggggcggctg cgcttctgga tccacatgca ggacgccgtg tactccctgc    780
agcagttcgg gttttcagag aaagatgctg atgaggtgaa aggaattttt gtagatacca    840
acttatactt cctggcgctg accttctttg tcgcagcgtt ccatcttctc tttgatttcc    900
tggcctttaa aaatgacatc agtttctgga agaagaagaa gagcatgatc ggcatgtcca    960
ccaaggcagt gctctggcgc tgcttcagca ccgtggtcat ctttctgttc ctgctggacg   1020
agcagacgag cctgctggtg ctggtcccgg cgggtgttgg agccgccatt gagctgtgga   1080
aagtgaagaa ggcattgaag atgactattt tttggagagg cctgatgccc gaatttcagt   1140
ttggcactta cagcgaatct gagaggaaaa ccgaggagta cgatactcag gccatgaagt   1200
acttgtcata cctgctgtac cctctctgtg tcgggggtgc tgtctattca ctcctgaata   1260
tcaaatataa gagctggtac tcctggttaa tcaacagctt cgtcaacggg gtctatgcct   1320
ttggtttcct cttcatgctg ccccagctct ttgtgaacta caaggtaagw crgtgtgtgc   1380
tgcccgcggc cggcccccgt ctcctgtgct gcccacagct gacctgggcc tgtctctcct   1440
gtttcagttg aagtcagtgg cacatctgcc ctggaaggcc ttcacctaca aggctttcaa   1500
caccttcatt gatgacgtct ttgccttcat catcaccatg cccacgtctc accggctggc   1560
ctgcttccgg gacgacgtgg tgtttctggt ctacctgtac cagcggtggc tttatcctgt   1620
ggataaacgc agagtgaacg agtttgggga gtcctacgag gagaaggcca cgcgggcgcc   1680
ccacacggac tgaaggccgc ccgggctgcc gccagccaag tgcaacttga attgtcaatg   1740
agtatttttg gaagcatttg gaggaattcc tagacattgc gttttctgtg ttgccaaaat   1800
cccttcggac atttctcaga catctcccaa gttcccatca cgtcagattt ggagctggta   1860
gcgcttacga tgcccccacg tgtgaacatc tgtcttggtc acagagctgg gtgctgccgg   1920
tcaccttgag ctgtggtggc tcccggcaca cgagtgtccg gggttcggcc atgtcctcac   1980
gcgggcaggg gtgggagccc tcacaggcaa gggggctgtt ggatttccat ttcaggtggt   2040
tttctaagtg ctccttatgt gaatttcaaa cacgtatgga attcattccg catggactct   2100
gggatcaaag gctctttcct cttttgtttg agagttggtt gttttaaagc ttaatgtatg   2160
tttctatttt aaaataaatt tttctggctg tggcaaaaaa aaaaaaaaaa aaaaaaaaaa   2220
aaaaaaaaaa aaaaaaaaaa aaaaaa                                        2246

<210> 1280
<211> 947
<212> DNA
<213> Homo sapiens

<400> 1280
ctcgagtttt ttttttttta ttkttcaagc agaaaacaag ctgcttttat tacagtatga     60
tgtcatgact catttgtaac agatccagcc tcagggacag ccctgtaagg cagcaagtgg    120
ggctggctcc aaatgggtat gagtctcaga atctttggta aggcagaact gaactgggct    180
gagaggtggt cttaaggcct gggcaggctc tattctctct ggactggctg cagcctgcag    240
tctaggagag gcccagtaca gcctggagct cctgagcctt gtcaacaggc agtgagccca    300
gagctgcttg aaagctgtcg gtgtgctgtt tggccaggaa cgtcaggagc agcaacagtg    360
cggccttggt gtctggtggg atcttgttgt cagccagaat gaggctgcag atacgcagaa    420
gctcgggagc cacatctata acctggtcag ggctgctctg gtacaggaag ctgaagaggc    480
gcccaatggt gacccactcc tccaagtcct ccttcagtgg cagggcatgc agtagggcag    540
ccagcacctg gggctctggt ttcctggtgg gactggccat caacaggcgg gcaagtgccc    600
cacagatgtt gtcacggaca cgatcatgtc gctcccgcgc caggagggga aaaaggagcc    660
ccagcagctt ggggaagtgt tcctgggcag ggtggccccc atgctctgcc agcacgccca    720
tcccgaagat ggcattgctt cgcacctcgg ggtctgcctc ttgggcggtg ctcaacagca    780
cagggagcag ccgagacaca aactgggctg aggcagcacc caggccctga atagtctctg    840
ccagaatgag gctgcagata cgcagaagct cgggagccac atctataacc tggtcagggc    900
tgctctggta caggaagctt gaagagcgcc ctcgtgccga attctgc                  947

<210> 1281
<211> 1171
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1086)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1095)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1103)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1114)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1157)
<223> n equals a,t,g, or c

<400> 1281
gccagggctc ttcattgcct gcctcttcag cggctctctc agcactatat cctctgcttt     60
taattcattg gcaactgtta cgatggaaga cctgattcga ccttggttcc ctgagttctc    120
tgaagcccgg gccatcatgc tttccagagg ccttgccttt ggctatgggc tgctttgtct    180
aggaatggcc tatatttcct cccagatggg acctgtgctg caggcagcaa tcagcatctt    240
tggcatggtt gggggaccgc tgctgggact cttctgcctt ggaatgttct ttccatgtgc    300
taaccctcct ggtgctgttg tgggcctgtt ggctgggctc gtcatggcct tctggattgg    360
catcgggagc atcgtgacca gcatgggcty cagcatgcca ccctctccct ctaatgggtc    420
cagcttctcc ctgcccacca atctaaccgt tgccactgtg accacactga tgcccttgac    480
taccttctcc aagcccacag ggctgcagcg gttctattcc ttgtcttact tatggtacag    540
tgctcacaac tccaccacag tgattgtggt gggcctgatt gtcagtctac tcactgggag    600
aatgcgaggc cggtccctga accctgcaac catttaccca gtgttgccaa agctcctgtc    660
cctccttccg ttgtcctgtc agaagcggct ccactgcagg agctacggcc aggaccacct    720
cgacactggc ctgtttcctg agaagccgag gaatggtgtg ctgggggaca gcagagacaa    780
ggaggccatg gccctggatg gcacagccta tcaggggagc agctccacct gcatcctcca    840
ggagacctcc ctgtgatgtt gactcaggac cccgcctctg tcctcactgt gccaggccat    900
agccagaggc caccctgtag tacagggatg agtcttggtg tgttctgcag ggacaggcct    960
ggatgatcta gctcatacca aaggaccttg ttctgagagg ttcttgcctg caggagaarc   1020
tgtcacatct caagcatgtg aggaccgktt ttctcgtgct tgscaatctg ktttttaaag   1080
gatcangctc gtaanggaag cangatcatg ccanaaatag ggatggaaat gcattctttt   1140
gggaaaaaag attaatngct ttctgattca c                                  1171

<210> 1282
<211> 1307
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1293)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1297)
<223> n equals a,t,g, or c

<400> 1282
aacttccggt gcctgcagag ctcggagcgg cggaggcaga gaccgaggct gcaccggcag     60
aggctgcggg gcggacgcgc gggccggcgc agccatggtg aagattagct tccagcccgc    120
cgtggctggc atcaagggcg acaaggctga caaggcgtcg gcgtcggccc ctgcgccggc    180
ctcggccacc gagatcctgc tgacgccggc tagggaggag cagcccccac aacatcgatc    240
caagaggggg rgctcagtgg gcggcgtgtg ctacctgtcg atgggcatgg tcgtgctgct    300
catgggcctc gtgttcgcct ctgtctacat ctacagatac ttcttccttg cgcagctggc    360
ccgagataac ttcttccgct gtggtgtgct gtatgaggac tccctgtcct cccaggtccg    420
gactcagatg gagctggaag aggatgtgaa aatctacctc gacgagaact acgagcgcat    480
caacgtgcct gtgccccagt ttggcggcgg tgaccctgca gacatcatcc atgacttcca    540
gcggggtctg actgcgtacc atgatatctc cctggacaag tgctatgtca tcgaactcaa    600
caccaccatt gtgctgcccc ctcgcaactt ctgggagctc ctcatgaacg tgaagagggg    660
gacctacctg ccgcagacgt acatcatcca ggaggagatg gtggtcacgg agcatgtcag    720
tgacaaggag gccctggggt ccttcatcta ccacctgtgc aacgggaaag acacctaccg    780
gctccggcgc cgggcaacgc ggaggcggat caacaagcgt ggggccaaga actgcaatgc    840
catccgccac ttcgagaaca ccttcgtggt ggagacgctc atctgcgggg tggtgtgagg    900
ccctcctccc ccagaacccc ctgccgtgtt cctcttttct tctttccggc tgctctctgg    960
ccctcctcct tccccctgct tagcttgtac tttggacgcg tttctataga ggtgacatgt   1020
ctctccattc ctctccaacc ctgcccacct ccctgtacca gagctgtgat ctctcggtgg   1080
ggggcccatc tctgctgacc tgggtgtggc ggagggagag gcgatgctgc aaagtgtttt   1140
ctgtgtccca ctgtcttgaa gctgggcctg ccaaagcctg ggcccacagc tgcaccggca   1200
gcccaagggg aaggaccggt tgggggaacc gggcatgttg aggccctggg caaggggatk   1260
gggctktggg ggcgggscgg catggkcttt aanaatnttc tgcacca                 1307

<210> 1283
<211> 1247
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (27)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1215)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1230)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1232)
<223> n equals a,t,g, or c

<400> 1283
tanttgccgc cggtggttct gggtccnctt nggccagttt tcgcggaatc aaatggcttt     60
gcctttatgg atcaccgcgc cggttggtaa tgccagatgt catcacgggc ttggtcctgg    120
tggtaataat tcgtcgcgct tgctcatgcc attggctggc ctgcggaccg cggtatgctc    180
accatctggc tggcgcatgt cactttttgt acggcttatg tggcggtcgt tatttcttca    240
agattgcggg aactggatcg ctcgatagaa gaagcagcga tggatctcgg tgcgacgccg    300
ctgaaagtgt ttttcgtcat tacgctaccg atgatcatgc ccgcgatcat ttctggctgg    360
ttactggctt ttactttgtc gcttgatgat ctggtgatcg ccagctttgt ttccgggccg    420
ggagccacca cgttaccgat gctggtcttt tccagcgtgc ggatgggggt gaatccggaa    480
atcaacgccc tggcaatccg ctggcctgcg cggcagcaaa cgccagcctg gcgattctcg    540
aatctggcga ctggcagcaa caggtggcgg atattgaagt acagctgcgc gagcaacttg    600
cccccgcccg tgaatgccga aatggttgcc gatgtgcgcg tactgggggc cattggcgtg    660
gtcgaaacca ctcatccggt gaatatggcg gcgctgcaaa aattctttgt cgaacagggt    720
gtctggatcc ggccttttgg caaactgatt tacctgatgc cgccctatat tattctcccg    780
caacagttgc agcgtctgac cgcagcggtt aaccgcgcgk tacaggatga aacatttttt    840
tgccaataac gagaagtccg cgtgagggtt tctggctaca ctttctgcaa acaagaaagg    900
agggttcatg aaactcatca gtaacgatct gcscgatggc gataaattgc cgcatcgtca    960
tgtctttaac ggcatgggtt acgatggcga taatatttca ccgcatctgg cgtgggatga   1020
tgttcctgcg ggaacgaaaa gttttgttgt cacctgctac gacccggatg cgccaaccgg   1080
ctccggctgg tggcactggg tagttgttaa cttacccgct gatacccgcg tattaccgca   1140
agggtttggc tctggtctgg tagcaatgcc agacggcgtt ttgcagacgc gtaccgactt   1200
tggtaaaacc gggtncccaa ttcgtccctn anagtgtagt ggtatta                 1247

<210> 1284
<211> 1484
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1079)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1225)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1424)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1470)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1478)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1482)
<223> n equals a,t,g, or c

<400> 1284
tccgctttgg gttttagaan ccaaccctct aggcttatct tgttttgcag ttttcatgtt     60
ttgacaattg cccaccattt acaatactca atttttgatt atgaaatgaa tagtaaaatt    120
caaacatatc taataataat ttgccttagt ttgattaata aattatatca aaaaacttgg    180
ggatagaaag aggctttttt ttccccctgt agtattttta aaacttttta gatgagctgg    240
atgaaacctt agtacattgg agctggagtt gtattgagta cagccccaac tctgaagcct    300
tatattcatg tcttaagtac cattgattgt tctgtgaatt gttgttagtt tcatatttga    360
cattgtagta atccaccttg cattttagtc tttgcaaaaa ggatattgct aggtatattc    420
ttatttctga ttgagtattg aatttacatt tttcagaatt tcattctttg tcattataat    480
ccaaaaacaa tgtccacatc agacttggaa cttctcactt caaaaatgaa atacagattt    540
agcagtgttg tacataatga tgtccaagca tttttccacc tgtttactga gttttccaac    600
catttactat gtgttgagat tggtgggttt tctggctgtt tttctgaggt gaatgacttg    660
ttacagagcc tcagtaagaa atttcaacta aaatcacaaa aacataaagt ccaggaaacc    720
accagaagat ggatttttag tgtttttgaa atcttgtatt tccttttgat atcatttact    780
cattttaatt ttacgactgc caacttgtta cggtattaat tatatgtatg tgtttatatg    840
tatgcatata atatatgtat atgtatatga agaataaagt taagatttgg tcaaactata    900
ttttcccatt caagtacaaa aatgttttca aggctgcaaa aagtgtacag ttgttaaaca    960
agttgtaaat aaagacttgt ataaaaaaaa aaaaaaaaaa ctcgaggggg ggcccggtac   1020
ccaattcgcc ctatagtgag tcgtattaca attcactggc cgtcgtttta caacgtcgng   1080
actgggaaaa ccctggcgtt acccaactta atcgccttgc agcacatccc cctttcgcca   1140
gctggcgtaa tagcgaagag gcccgcaccg atcgcccttc ccaacagttg cgcagcctga   1200
atggcgaatg gcaaattgta agcgntaata ttttgttaaa attcgcgtta aatttttgtt   1260
aaatcagctc attttttaac caataggccg aaatcggcaa aatcccttat aaatcaaaag   1320
aatagaccga gatagggttg agtgttgttc cagtttggaa caagagtcca ctattaaaga   1380
accgtggact ccaacgtcaa agggcgaaaa accgtctatc aggnccgatg gcccactacg   1440
tgaaccatca ccctaatcaa gttttttggn gtcgaggngc cnta                    1484

<210> 1285
<211> 2928
<212> DNA
<213> Homo sapiens

<400> 1285
gtccggacgt aatcgtggtt tttgttctgc aataggcggc ttagagggag gggctttttc     60
gcctatacct actgtagctt ctccacgtat ggaccctaaa ggctactgct gctactacgg    120
ggctagacag ttactgtctc agctctagga tgtgcgttct tccactagaa gctcttctga    180
gggaggtaat taaaaaacag tggaatggaa aaacagtgct gtagtcatcc tgtaatatgc    240
tccttgtcaa caatgtatac attcctgcta ggtgccatat tcattgcttt aagctcaagt    300
cgcatcttac tagtgaagta ttctgccaat gaagaaaaca agtatgatta tcttccaact    360
actgtgaatg tgtgctcaga actggtgaag ctagttttct gtgtgcttgt gtcattctgt    420
gttataaaga aagatcatca aagtagaaat ttgaaatatg cttcctggaa ggaattctct    480
gatttcatga agtggtccat tcctgccttt ctttatttcc tggataactt gattgtcttc    540
tatgtcctgt cctatcttca accagccatg gctgttatct tctcaaattt tagcattata    600
acaacagctc ttctattcag gatagtgctg aagaggcgtc taaactggat ccagtgggct    660
tccctcctga ctttattttt gtctattgtg gccttgactg ccgggactaa aactttacag    720
cacaacttgg caggacgtgg atttcatcac gatgcctttt tcagcccttc caattcctgc    780
cttcttttca gaagtgagtg tcccagaaaa gacaattgta cagcaaagga atggactttt    840
cctgaagcta aatggaacac cacagccaga gttttcagtc acatccgtct tggcatgggc    900
catgttctta ttatagtcca gtgttttatt tcttcaatgg ctaatatcta taatgaaaag    960
atactgaagg aagggaacca gctcactgaa agcatcttca tacagaacag caaactctat   1020
ttctttggca ttctgtttaa tgggctgact ctgggccttc agaggagtaa ccgtgatcag   1080
attaagaact gtggattttt ttatggccac agtgcatttt cagtagccct tatttttgta   1140
actgcattcc agggcctttc agtggctttc attctgaagt tcctggataa catgttccat   1200
gtcttgatgg cccaggttac cactgtcatt atcacaacag tgtctgtcct ggtctttgac   1260
ttcaggccct ccctggaatt tttcttggaa gccccatcag tccttctctc tatatttatt   1320
tataatgcca gcaagcctca agttccggaa tacgcaccta ggcaagaaag gatccgagat   1380
ctaagtggca atctttggga gcgttccagt ggggatggag aagaactaga aagacttacc   1440
aaacccaaga gtgatgagtc agatgaagat actttctaac tggtacccac atagtttgca   1500
gctctcttga accttatttt cacattttca gtgtttgtaa tatttatctt ttcactttga   1560
taaaccagaa atgtttctaa atcctaatat tctttgcata tatctagcta ctccctaaat   1620
ggttccatcc aaggcttaga gtacccaaag gctaagaaat tctaaagaac tgatacagga   1680
gtaacaatat gaagaattca ttaatatctc agtacttgat aaatcagaaa gttatatgtg   1740
cagattattt tccttggcct tcaagcttcc aaaaaacttg taataatcat gttagctata   1800
gcttgtatat acacatagag atcaatttgc caaatattca caatcatgta gttctagttt   1860
acatgccaaa gtcttccctt tttaacatta taaaagctag gttgtctctt gaattttgag   1920
gccctagaga tagtcatttt gcaagtaaag agcaacggga ccctttctaa aaacgttggt   1980
tgaaggacct aaatacctgg ccataccata gatttgggat gatgtagtct gtgctaaata   2040
ttttgctgaa gaagcagttt ctcagacaca acatctcaga attttaattt ttagaaattc   2100
atgggaaatt ggatttttgt aataatcttt tgatgtttta aacattggtt ccctagtcac   2160
catagttacc acttgtattt taagtcattt aaacaagcca cggtggggct tttttctcct   2220
cagtttgagg agaaaaatct tgatgtcatt actcctgaat tattacattt tggagaataa   2280
gagggcattt tattttatta gttactaatt caagctgtga ctattgtata tctttccaag   2340
agttgaaatg ctggcttcag aatcatacca gattgtcagt gaagctgatg cctaggaact   2400
tttaaaggga tcctttcaaa aggatcactt agcaaacaca tgttgacttt taactgatgt   2460
atgaatatta atactctaaa aatagaaaga ccagtaatat ataagtcact ttacagtgct   2520
acttcacact taaaagtgca tggtattttt catggtattt tgcatgcagc cagttaactc   2580
tcgtagatag agaagtcagg tgatagatga tattaaaaat tagcaaacaa aagtgacttg   2640
ctcagggtca tgcagctggg tgatgataga agagtgggct ttaactggca ggcctgtatg   2700
tttacagact accatactgt aaatatgagc tttatggtgt cattctcaga aacttataca   2760
tttctgctct cctttctcct aagtttcatg cagatgaata taaggtaata tactattata   2820
taattcattt gtgatatcca caataatatg actggcaaga attggtggaa atttgtaatt   2880
aaaataatta ttaaacctaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                2928

<210> 1286
<211> 1424
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<400> 1286
cggggggatt ncgggngcga tacttcgtga cactatagaa ggtacgcctg caggtaccgg     60
tccggaattc ccgggtcgac ccacgcgtcc ggcgtgcgag agatcctgtc cgactgcgcc    120
ctgcccatcg cggtgctcgc cttctccctc atcagctccc atggcttccg ggaaatcgag    180
atgagcaagt tccgctacaa ccccagcgag agcccctttg cgatggcgca gatccagtcg    240
ctgtccctga gggccgtcag cggtgccatg ggcctcggct tcctgctgtc catgctcttc    300
ttcatcgagc agaacttggt ggccgccttg gtgaatgcac cggagaacag gctggtgaag    360
ggcactgcct accactggga cctcctgctc ctcgccatca tcaacacagg gctgtctctg    420
tttgggctgc cttggatcca tgccgcctac ccccactccc cgctgcacgt gcgagccctg    480
gccttagtgg aggagcgtgt ggagaacgga cacatctatg acacgattgt gaacgtgaag    540
gagacgcggc tgacctcgct gggcgccagc gtcctggtgg gcctgtccct gttgctgctg    600
ccggtcccgc ttcagtggat ccccaagccc gtgctctatg gcctcttcct ctacatcgcg    660
ctcacctccc tcgatggcaa ccagctcgtc cagcgcgtgg ccctgctgct caaggagcag    720
actgcgtacc ccccgacaca ctacatccgg agggtgcccc agaggaagat ccactacttc    780
acgggcctgc aggtgcttca gctgctgctg ctgtgtgcct tcggcatgag ctccctgccc    840
tacatgaaga tgatctttcc cctcatcatg atcgccatga tccccatccg ctatatcctg    900
ctgccccgaa tcattgaagc caagtacttg gatgtcatgg acgctgagca caggccttga    960
ctggcagacc ctgcccacgc cccattcgcc agccctccac gtcctcccag gctggctctg   1020
gagctgtgag gggaggtgta ggtgtgtggg tgactgctct gtgctgcgcc ttctcatggc   1080
tgactcaggc ctggggcatc tgggcattgt aggggtgcag tggtatgtgc ccacccctct   1140
cccattatcc tttagcttta ggccaagagc gttgctcagg gcagcttctg cccagggtgg   1200
gtgggactga gcaggatgga ttttcttttg ataaaagagt cgatgcctga aagagaaacc   1260
atttccttga ttgtgtaagg aacttgctgg acgcacatta gagaataaag ctcctgtttc   1320
taggcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1380
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gggg                    1424

<210> 1287
<211> 1545
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (60)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (227)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1332)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1541)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1544)
<223> n equals a,t,g, or c

<400> 1287
tcantgggtt aaaaaagaaa anccccccct ggggcccaat tacgcaaaac cggcttttcn     60
ccggcgcgtt ggccgattca ttaatcargt tgcacgacag gtttcccgac tgraaagcgg    120
cagtgagcgc aacgcaatta atgtgagtta gcttcactca ttaggcaccc caggctttac    180
actttatgct tccggctcgt atgttgtgtg raattgtgag cggatancaa tttcacacag    240
gaaacagcta tgaccatgat tacgccaagc tctaatacga ctcactatag ggaaagctgg    300
tacgcctgca ggtaccggtc cggaattccc gggtcgaccc acgcgtccgc atggctgaag    360
cgctgccgct gccgctactg ccgctgcagg gaaaatgctg agccctcccg ggccgggtgg    420
gcggcggcgg cgagggcggc gacggggacc cgcttcccga gcgcggcggc ggcggccatg    480
gcccggctgg ctgactactt catcgtggta ggctatgacc acgagaagcc aggatcagga    540
gaaggtctgg ggaaaataat ccagagattt ccacagaagg actgggatga tacacctttt    600
ccacagggaa ttgagttgtt ttgtcagcct ggcgggtggc agctgtccag agagaggaag    660
cagccaacgt tctttgtggt tgtcctgaca gacattgact cagatcgaca ttactgctca    720
tgcctaacct tctatgaggc agagatcaat cttcagggaa caaagaagga agagattgaa    780
ggtgaagcaa aagtgtctgg tttaattcag cctgcagaag tgtttgctcc caaaagcctg    840
gtgttggtat ccagattata ttatccagaa atttttaggg cttgcctggg tttgatctat    900
accgtgtatg tggacagcct gaatgtctcc ttggaaagtc taattgcaaa cctttgtgcc    960
tgccttgtcc cagcggctgg agggtctcag aagctgtttt ctttgggtgc aggagataga   1020
cagttgatcc agactccttt acatgatagt cttcctatca cgggcactag tgtggctctc   1080
ctgttccagc aattgggcac ggtggctcac gcctgtaatc tcagcacttt gggaggccga   1140
ggcggscagc tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaatccca   1200
tctctactaa aaatacaaaa aattagccgg gcatggtggc ccgtgtctgc agtcccagct   1260
actcgggagg ctgaggcagg agaatggcgt gaacccaaga ggcggagctt gcagtgagct   1320
gagatcgcac cnctacactc cagactgggc gacagagcga gactccatct caaaaacaat   1380
aataataata ataataatgt aaaacttaag aaagcatgtg acatttaaga ataaagaatt   1440
taagtagtat ttcaaaaaaa aaaaaaaagg gcggccgctc tagaggatcc aagcttacgt   1500
acgcgtgcat gcgacgtcat agctcttcta tagtgtcacc naant                   1545

<210> 1288
<211> 1769
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<400> 1288
aagggnnaac tntctaacng gtaattactc ngacactata gttaggtacg cctgcaggta     60
ccggtccgga attcccgggt cgacccacgc gtccgatcag acctacagca gacattgcag    120
gcctgaagaa aggtggtcac aagaggggtg gaacattcct gcaaatggtt tcaatatatg    180
cagatgtctc gatataggaa tgaaattacg tctttggaac aacttaaata agtcaaatat    240
acttggagct ttaaaaatta aaaggagaga gattcgagca ccttttctgc tgccatgaca    300
accatgcaag gaatggaaca ggccatgcca ggggctggcc ctggtgtgcc ccagctggga    360
aacatggctg tcatacattc acatctgtgg aaaggattgc aagagaagtt cttgaaggga    420
gaacccaaag tccttggggt tgtgcagatt ctgactgccc tgatgagcct tagcatggga    480
ataacaatga tgtgtatggc atctaatact tatggaagta accctatttc cgtgtatatc    540
gggtacacaa tttgggggtc agtaatgttt attatttcag gatccttgtc aattgcagca    600
ggaattagaa ctacaaaagg cctggtccga ggtagtctag gaatgaatat caccagctct    660
gtactggctg catcagggat cttaatcaac acatttagct tggcgtttta ttcattccat    720
cacccttact gtaactacta tggcaactca aataattgtc atgggactat gtccatctta    780
atgggtctgg atggcatggt gctcctctta agtgtgctgg aattctgcat tgctgtgtcc    840
ctctctgcct ttggatgtaa agtgctctgt tgtacccctg gtggggttgt gttaattctg    900
ccatcacatt ctcacatggc agaaacagca tctcccacac cacttaatga ggtttgaggc    960
caccaaaaga tcaacagaca aatgctccag aaatctatgc tgactgtgac acaagagcct   1020
cacatgagaa attaccagta tccaacttcg atactgatag acttgttgat attattatta   1080
tatgtaatcc aattatgaac tgtgtgtgta tagagagata ataaattcaa aattatgttc   1140
tcattttttt ccctggaact caataactca tttcactggc tctttatcga gagtactaga   1200
agttaaatta ataaataatg catttaatga ggcaacagca cttgaaagtt tttcattcat   1260
cataagaact ttatataaag gcattacatt ggcaaataag gtttggaagc agaagagcaa   1320
aaaaaagata ttgttaaaat gaggcctcca tgcaaaacac atacttccct cccatttatt   1380
taactttttt tttctcctac ctatggggac caaagtgctt tttccttcag gaagtggaga   1440
tgcatggcca tctccccctc cctttttcct tctcctgctt ttctttcccc atagaaagta   1500
ccttgaagta gcacagtccg tccttgcatg tgcacgagct atcatttgag taaaagtata   1560
catggagtaa aaatcatatt aagcatcaga ttcaacttat attttctatt tcatcttctt   1620
cctttccctt ctcccacctt ctactgggca taattatatc ttaatcatat atggaaatgt   1680
gcaacatatg gtatttgtta aatacgtttg tttttattgc agagcaaaaa taaatcaaat   1740
tagaagcaat aaaaaaaaaa aaaaaaaaa                                     1769

<210> 1289
<211> 1649
<212> DNA
<213> Homo sapiens

<400> 1289
gaagttctct tcacggagcc gcgcggctgc gggggcgcaa atagggtcag tgggccgctt     60
ggcggtgtcg ttgcggtacc aggtccgcgt gaggggttcg ggggttctgg gcaggcacaa    120
tggcgtctcg agcaggcccg cgagcggccg gcaccgacgg cagcgacttt cagcaccggg    180
agcgcgtcgc catgcactac cagatgagtg tgaccctcaa gtatgaaatc aagaagctga    240
tctacgtaca tctggtcata tggctgctgc tggttgctaa gatgagcgtg ggacacctga    300
ggctcttgtc acatgatcag gtggccatgc cctatcagtg ggaatacccg tatttgctga    360
gcattttgcc ctctctcttg ggccttctct cctttccccg caacaacatt agctacctgg    420
tgctctccat gatcagcatg ggactctttt ccatcgctcc actcatttat ggcagcatgg    480
agatgttccc tgctgcacag cagctctacc gccatggcaa ggcctaccgt ttcctctttg    540
gtttttctgc cgtttccatc atgtacctgg tgttggtgtt ggcagtgcaa gtgcatgcct    600
ggcagttgta ctacagcaag aagctcctag actcttggtt caccagcaca caggagaaga    660
agcataaatg aagcctcttt ggggtgaagc ctggacatcc catcgaatga aaggacacta    720
gtacagcggt tccaaaatcc cttctggtga ttttagcagc tgtgatgttg gtacctggtg    780
cagaccaggc caaagttctg gaaagctcct tttgccatct gctgaggtgg caaaactata    840
atttattcct ggttggctag aactgggtga ccracagcta tgaaacaaat ttcagctgtt    900
tgaagttgaa ctttgaggtt tttctttaag aatgagcttc gtccttgcct ctactcggtc    960
attctcccca tttccatcca ttacccctta gccattgaga ctaaaggaaa tagggaataa   1020
atcaaattac ttcatctcta ggtcacgggt caggaaacat ttgggcagct gctcccttgg   1080
caggctgtgg tctcctctgc aaagcatttt aattaaaaac ctcaataaag atggccctgc   1140
ccacactgtg ccttgtgttt ggggcttgat agagtgtgaa aggtgtgttg cttgaaaggt   1200
gtggccttag acactaggag atgatgggta gaagctcctt gagaaaccta gcagtggcca   1260
tagagaagta gactgggtat ggggaaccta agtcatagtt gtaacctaca gctgattggt   1320
aagaactatg ggccagacat ttaatctctc catctatgaa atagtccatt ctcatttatc   1380
taccttaggt tatgggctct tcttttagtt ggatattcac atttatcttt cagtgttaac   1440
tgggtatcag ttatgagtct actactgtat aatggcatcc aaaagaattt taaagtacct   1500
cggtttatag ggatttacaa ttcagtagaa acttgttatt catgtgaaac agtgaacata   1560
atatctaatg atgtggagca agtacattaa aaacaggaag gaagagatct gtgattaaac   1620
taaaggccct ttcacaccta aaaaaaaaa                                     1649

<210> 1290
<211> 906
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (826)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (885)
<223> n equals a,t,g, or c

<400> 1290
gctcgctctt ccaatactca cgccctagct acagaggtca aggaaggttt ccccaggagc     60
agttttggtt tcagacggcg ccgtctcccg cgaaagtcct gagaggagcc cagccttttc    120
cgcctgccgc ccccggatgg gatggttgag gccggggcca cgccccctct gcccccctgc    180
gagggcatcc tgggctttct cccaccgctt tccgagcccg cttgcacctc ggcgatcccc    240
gactcccttc tttatggcgt cgctcctgtg ctgtgggccg aagctggccg cctgcggcat    300
cgtcctcagc gcctggggag tgatcatgtt gataatgctc ggaatatttt tcaatgtcca    360
ttccgctgtg ttgattgagg acgttccctt cacggagaaa gattttgaga atggccccca    420
gaacatatac aacctttacg agcaagtcag ctacaactgt ttcatcgctg caggccttta    480
cctcctcctc ggaggcttct ctttctgcca agttcggctc aataagcgca aggaatacat    540
ggtgcgctag ggccccggcg cgtttccccg ctccagcccc tcctctattt aaagactccc    600
tgcaccgtgt cacccaggtc gcgtcccacc cttgccggcg ccctctgtgg gactgggttt    660
cccgggcgag agactgaatc ccttctccca tctctggcat ccggcccccg tggagagggc    720
tgaggctggg gggctgttcc gtctctccac ccttcgctgt gtcccgtatc tcaataaaga    780
gaatctgctc tcttcaaaaa aaaaaaaaaa aaaaattggg gggaantttt aggggggccg    840
gggcccatgg tttttccacc cggggggggt aacccgtaaa gtttncccat ttggccctta    900
aggggg                                                               906

<210> 1291
<211> 766
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (690)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (698)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (703)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (706)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (733)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (735)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (739)
<223> n equals a,t,g, or c

<400> 1291
tttcgaaatt aaccctcact aaagggaaca aaagctggag ctccaccgcg gtggcggccg     60
ctctagaact agtggatccc ccgggctkya ggaattcggc acgagggtaa ctgggggtgt    120
tatactgagc agcagcgttg tgatgggtat tggcattgcc caaatggaag ggatgaaacc    180
aattgtacca tgtgccagaa ggaagaattt ccatgttccc gaaatggtgt ctgttatcct    240
cgttctgatc gctgcaacta ccagaatcat tgcccaaatg gctcagatga aaaaaactgc    300
tttttttgcc aaccaggaaa tttccattgt aaaaacaatc gttgtgtgtt tgaaagttgg    360
gtgtgtgatt ctcaagatga ctgtggtgat ggcagcgatg aagaaaattg cccagtaatc    420
gtgcctacaa gagtcatcac tgctgccgtc atagggagcc tcatctgtgg cctgttactc    480
gtcatagcat tgggatgtac ttgtaagctt tattctctga gaatgtttga aagaagatca    540
tttgaaacac agttgtcaag artggaagca gaattggtaa gaagagaast tctycctygt    600
atggmcaatt gattgctcaa ggkttaattc accagttgaa gaattttctg gttggtcacc    660
taatcaagct tctggtttgg aaaatctgan gctaccgnwc canctnaast tggaattact    720
ttatagctct tgnangcana caagcacaat ttggaaaccg attttt                   766

<210> 1292
<211> 1627
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> n equals a,t,g, or c

<400> 1292
cggagcggtt tgtaatgtat tnctggattt tattttgctg tattagctcc tcaagagtta     60
ctgatctatg aaatggcaga gaatggaaaa aattgtgacc agagacgtgt agcaatgaac    120
aaggaacatc ataatggaaa tttcacagac ccctcttcag tgaatgaaaa gaagaggagg    180
gagcgggaag aaaggcagaa tattgtcctg tggagacagc cgctcattac cttgcagtat    240
ttttctctgg aaatccttgt aatcttgaag gaatggacct caaaattatg gcatcgtcaa    300
agcattgtgg tgtctttttt actgctgctt gctgtgctta tagctacgta ttatgttgaa    360
ggagtgcatc aacagtatgt gcaacgtata gagaaacagt ttcttttgta tgcctactgg    420
ataggcttag gaattttgtc ttctgttggg cttggaacag ggctgcacac ctttctgctt    480
tatctgggtc cacatatagc ctcagttaca ttagctgctt atgaatgcaa ttcagttaat    540
tttcccgaac caccctatcc tgatcagatt atttgtccag atgaagaggg cactgaagga    600
accatttctt tgtggagtat catctcaaaa gttaggattg aagcctgcat gtggggtatc    660
ggtacagcaa tcggagagct gcctccatat ttcatggyca gagcagctcg cctctcaggt    720
gctgaaccag atgatgaaga gtatcaggaa tttgaagaga tgctggaaca tgcagagtct    780
gcacaagact ttgcctcccg ggccaaactg gcagttcaaa aactagtaca gaaagttgga    840
ttttttggaa ttttggcctg tgcttcaatt ccaaatcctt tatttgatct ggctggaata    900
acgtgtggac actttctggt acctttttgg accttctttg gtgcaaccct aattggaaaa    960
gcaataataa aaatgcatat ccagaaaatt tttgttataa taacattcag caagcacata   1020
gtggagcaaa tggtggcttt cattggtgct gtccccggca taggtccatc tctgcagaag   1080
ccatttcagg agtacctgga ggctcaacgg cagaagcttc accacaaaag cgaaatgggc   1140
acaccacagg gagaaaactg gttgtcctgg atgtttgaaa agttggtcgt tgtcatggtg   1200
tgttacttca tcctatctat cattaactcc atggcacaaa gttatgccaa acgaatccag   1260
cagcggttga actcagagga gaaaactaaa taagtagaga aagttttaaa ctgcagaaat   1320
tggagtggat gggttctgcc ttaaattggg aggactccaa gccgggaagg aaaattccct   1380
tttccaacct gtatcaattt ttacaacttt tttcctgaaa gcagtttwst ccctgtggtg   1440
tgcccatttc gcttttgtgg tgaagcttct gccgttgagc ctccaggtac tcctgaaatg   1500
gcttctgcag agatggacct atgccgggga cagcaccaat gaaagccacc atttgctcca   1560
ctatgtgctt gctgaatgtt attataacaa aaattttctc ggacgcgtgg gcggacgcgt   1620
gggtcga                                                             1627

<210> 1293
<211> 1518
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (61)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1365)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1450)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1507)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1515)
<223> n equals a,t,g, or c

<400> 1293
agtacgccat aggcttccat tgcgcaatgg tgagtattcc ggtaacttgc catttgcagt     60
ncatcaagtg atcatatgcc aagtacgccc cctattgacg tcaatgcggt aaatggcccg    120
cctggcatta tgcccagtac atgccttatg ggactttcct acttgccagt acatctacgt    180
attagtcatc gctattacca tggtgatgcg gttttgccag tacatcaatg ggcgtggata    240
gcggtttgac tcacggggat ttccaagtct ccaccccatt gacgtcaatg ggagtttgtt    300
ttggcaccaa aatcaacggg actttccaaa atgtcgtaac aactccgccc cattgacgca    360
aatgggcggt aggcgtgtac ggtgggaggt ctatataagc agagctcgtt tagtgaaccg    420
tcagatcgcc tggagacgcc atccacgctg ttttgacctc catagaagac accgggaccg    480
atccagcctc cggactctag cctaggccgc gggacggata acaatttcac acaggaaaca    540
gctatgacca ctaggctttt gcaaaaagct atttaggtga cactatagaa ggtacgcctg    600
caggtaccgg tccggaattc ccgggtcgac ccacgcgtcc gcacacgccg gaggagccgg    660
gtggtgcaga gccggagccg gagccggagc cgcgccgcgc cgcaccatgg cgcccaccct    720
ggccactgcc catcggcgcc gctggtggat ggcctgcacg gccgtgctgg agaacctcct    780
cttctcggca gtcctcctgg gctggggctc gctgctcatc atgctcaagt cagagggctt    840
ttactcctac ctgtgtaccg agccagagaa tgtcaccaat ggcacagtgg gcggcacagc    900
agagccgggg cacgaggagg tgagctggat gaacggctgg ctcagctgcc aggcccagga    960
cgagatgcta aatttggcct tcactgtggg ctcctttctg ctcagtgcca tcaccctgcc   1020
cctgggtatc gtcatggaca agtatggccc gaggaagctc aggctgctgg gcagcgcctg   1080
cttcgcggtt tcctgcttgc tgattgcgta cggagcaagt aaaccaaacg ctctctccgt   1140
gctcatcttc atcgccctgg ctctgaatgg ctttggtggg atgtgtatga ccttcacctc   1200
attaacactg cccaacatgt tcggcgacct tcggtccacg tttattgctt gatgattggg   1260
tctacgccty ctcggcagta actttycagg aatcaagctc atctatgatg ctggtgtctc   1320
cttcatcgtc gtcctcgtgg tcttgggccg gcttgctccg ggctnggttt tccttcaayt   1380
gctctttaat tggscccttg aagccctttc cgggggccgg aagaacatkg aawtaayccg   1440
gtgaaaatyn aarttcaact tggcttgggc ttttaaccac caagattaca agggaaacaa   1500
tttttanaaa gcaangtg                                                 1518

<210> 1294
<211> 1605
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (806)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1502)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1550)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1560)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1578)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1596)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1597)
<223> n equals a,t,g, or c

<400> 1294
atagatatcc agttcaccgg aagtaatcgc cccgcgcacc acaggagtcg ttccgagttg     60
cactttattc accgtcggta cgccgtggct ttccagcacc tgcaaaatga tattgccgag    120
tagcgcacct tcggtatcga tttttgaacc gactttaacg ggggaagccg cctgtagcgg    180
caggctcacg gctgccaaca taaccagtga acctgcccag agctttaaga gtggcatgat    240
gctttcctca ttcttttact gttgttttca gcgaattaag agaaaagcat agttgataat    300
ggcggggtta gcttgagcgg aaggattcag ttgcagaatc agataaatac ttaagaggca    360
tattcggtcc ggcgtttcct gccggatgcg gcgcgagcgc cttatccggc ctacaaargg    420
cgcaaacgtc gcgcccttac taaagcatta cagcaacttc aaactcgcct ttcttaacgc    480
gtgcggaatc agtgccgata aagacattga acttgccagg ctcggcgtca tatttcatct    540
gttgattcca gaacttcagc gcctcaatat cgatcgggaa gctgacagtc tgagtttcgc    600
ccggtttcag ggtgattttc tcaaagcctt tcagctgttt cacagggcga ctcatggaag    660
ccgtcacatc ctgcaagtac atctgcacta ccgtggcacc ctcgcgctta ccggtgttcg    720
tcacctgcac gctggcagtc actttgccgt cacgcttcat ggtcggcgca gaaagtttca    780
catcagagac ggtgaaagtg gtgtanctca gcccatagcc gaacggatac aacgccccgt    840
tagcttcatc aaaataacgc gaagtgtatt tgttcggctt gtcggcatta tacgggcgac    900
cggtattcag atggctgtag twyaccggga tctgcccgac agaacgcggg aaggacattg    960
gcagcttgcc ggacgggttg taatcgccaa acaatacatc ggcaattgca ttaccgcctt   1020
cagtccccgc aaaccaggtt tccagaatcg catcagcctg ctgatcttct ttcaccagcg   1080
ccagcggacg cccgttcatc agcaccagca ccagcggttt accggtggct ttcagcgccg   1140
caatcaagtc acgttggctt tgcggaatag tgatatcggt ccggctggag gcttcgtgcg   1200
ccatcccctg tgcttcaccg actacagcca ccaccacatc agattgtttc gccgtctgca   1260
ccgcttcatc aatcatctct tgcggcgaac gcggatcgac tttgaccgct tcttcatact   1320
gattcaggaa atcgataatg cctttgtcac tggtaacgtt cgcccctttg gcatacagca   1380
ctttaccgtt ttcaccgacg gcatttttaa tcccggtcag tacggtcacg gattgatcgg   1440
caacaccggc tgcggaccag ctgcccatca cgtcacgttt actgtccgcc agtggccmaa   1500
cnaccgcaat ggtggccgat tttttcagcg gtaacgtttc gagacggggn tcttaccccn   1560
agaagggatt gaaatttncc catcccgtcc cccccnngtc agacg                   1605

<210> 1295
<211> 1081
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1076)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1078)
<223> n equals a,t,g, or c

<400> 1295
gctgagcacg ccctctgagc cgctcggtgg acaccaggca ctctagtagg cctggcctac     60
ccagaaacag caggagagag aagaaacagg ccagctgtga gaagccaagg acaccgagtc    120
agtcatggca cctaaggcgg caaagggggc caagccagag ccagcaccag ctccacctcc    180
acccggggcc aaacccgagg aagacaagaa ggacggtaag gagccatcgg acaaacctca    240
aaaggcggtg caggaccata aggagccatc ggacaaacct caaaaggcgg tgcagcccaa    300
gcacgaagtg ggcacgagga gggggtgtcg ccgctaccgg tgggaattaa aagacagcaa    360
taaagagttc tggctcttgg ggcacgctga gatcaagatt cggagtttgg gctgcctaat    420
agctgcaatg atactgttgt cctcactcac cgtgcacccc atcttgaggc ttatcatcac    480
catggagata tccttcttca gcttcttcat cttactgtac agctttgcca ttcatagata    540
catacccttc atcctgtggc ccatttctga cctcttcaac gacctgattg cttgtgcgtt    600
ccttgtggga gccgtggtct ttgctgtgag aagtcggcga tccatgaatc tccactactt    660
acttgctgtg atccttattg gtgcggctgg agtttttgct tttatcgatg tgtgtcttca    720
aagaaaccac ttcagaggca agaaggccaa aaagcatatg ctggttcctc ctccaggaaa    780
ggaaaaagga ccccagcagg gcaagggacc agaacccgcc aagccaccag aacctggcaa    840
gccaccaggg ccagcaaagg gaaagaaatg acttggagga ggctcctggt gtctgaaacg    900
gcagtgtatt ttacagcaat atgtttccac tctcttcctt gtcttctttc tggaatggtt    960
ttcttttcca ttttcattac cacctttgct tggaaaagaa tggattaatg gattctaaaa   1020
gcctaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aacagnancc   1080
c                                                                   1081

<210> 1296
<211> 1118
<212> DNA
<213> Homo sapiens

<400> 1296
gcagaaaggc agaaaggaga aaattcagga taactctcct gaggggtgag ccaagccctg     60
ccatgtagtg cacgcaggac atcaacaaac acagataaca ggaaatgatc cattccctgt    120
ggtcacttat tctaaaggcc ccaaccttca aagttcaagt agtgatatgg atgactccac    180
agaaagggag cagtcacgcc ttacttcttg ccttaagaaa agagaagaaa tgaaactgaa    240
ggagtgtgtt tccatcctcc cacggaagga aagcccctct gtccgatcct ccaaagacgg    300
aaagctgctg gctgcaacct tgctgctggc actgctgtct tgctgcctca cggtggtgtc    360
tttctaccag gtggccgccc tgcaagggga cctggccagc ctccgggcag agctgcaggg    420
ccaccacgcg gagaagctgc cagcaggagc aggagccccc aaggccggcc tggaggaagc    480
tccagctgtc accgcgggac tgaaaatctt tgaaccacca gctccaggag aaggcaactc    540
cagtcagaac agcagaaata agcgtgccgt tcagggtcca gaagaaacag tcactcaaga    600
ctgcttgcaa ctgattgcag acagtgaaac accaactata caaaaaggat cttacacatt    660
tgttccatgg cttctcagct ttaaaagggg aagtgcccta gaagaaaaag agaataaaat    720
attggtcaaa gaaactggtt acttttttat atatggtcag gttttatata ctgataagac    780
ctacgccatg ggacatctaa ttcagaggaa gaaggtccat gtctttgggg atgaattgag    840
tctggtgact ttgtttcgat gtattcaaaa tatgcctgaa acactaccca ataattcctg    900
ctattcagct ggcattgcaa aactggaaga aggagatgaa ctccaacttg caataccaag    960
agaaaatgca caaatatcac tggatggaga tgtcacattt tttggtgcat tgaaactgct   1020
gtgacctact tacaccatgt ctgtagctat tttcctcctt tctctgtacc tytaagaaga   1080
aagaatctac tgaaaatacc amaaaaaaaa aaaaaaaa                           1118

<210> 1297
<211> 748
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (622)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (725)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (734)
<223> n equals a,t,g, or c

<400> 1297
gcgagcacgt tagaaagcct gacatggcct gactcgggac agctcagagc agggcagaac     60
tggggacact ctgggccggc cttctgcctg catggacgct ctgaagccac cctgtctctg    120
gaggaaccac gagcgaggga agaaggacag ggactcgtgt ggcaggaaga actcagagcc    180
gggaagcccc cattcactag aagcactgag agatgcggcc ccctcgcagg gtctgaattt    240
cctgctgctg ttcacaaaga tgctttttat ctttaacttt ttgttttccc cacttccgac    300
cccggcgttg atctgcatcc tgacatttgg agctgccatc ttcttgtggc tgatcaccag    360
acctcaaccc gtcttacctc ttcttgacct gaacaatcag tctgtgggaa ttgagggagg    420
agcacggaag ggggtttccc agaagaacaa tgacctaaca agttgctgct tctcagatgc    480
caagactatg tatgaggttt tccaaagagg actcgctgtg tctgacaatg ggccctgctt    540
gggatataga aaaccaaacc agccctacag atggctatct tacaaacagg tgtctgatar    600
agcarartac ctgggttcct gnctcttgca taaaggttat aatcatcacc agaccagttt    660
gtcggcatct ttgctcaraa taggccarag tggatcatct ccgaattggc ttgtaacgac    720
tttgnactga cttntaactt gaccaaac                                       748

<210> 1298
<211> 2444
<212> DNA
<213> Homo sapiens

<400> 1298
ggcggaggcg gaggcggccc cgggctcggg cggctgggat ggagcagaag agcgcggaca     60
ccggagggca cgcagctgac ggagctgcgc tgcgttcgcc tcgtttgcct cgcgccctcc    120
actggagctg ttcgcgcctc ccggctccca ccgcagccca cccggcagag gagtcgctac    180
cagcgcccag tgcgctctgt cagtccgcaa actccttgcc gcccgccccg ggctgggcac    240
caaataccag gctaccatgg tctacaagac tctcttcgct ctttgcatct taactgcagg    300
atggagggta cagagtctgc ctacatcagc tcctttgtct gtttctcttc cgacaaacat    360
tgtaccaccg accaccatct ggactagctc tccacaaaac actgatgcag acactgcctc    420
cccatccaac ggcactcaca acaactcggt gctcccagtt acagcatcag ccccaacatc    480
tctgcttcct aagaacattt ccatagagtc cagagaagag gagatcacca gcccaggttc    540
gaattgggaa ggcacaaaca cagacccctc accttctggg ttctcgtcaa caagcggtgg    600
agtccactta acaaccacgt tggaggaaca cagctcgggc actcctgaag caggcgtggc    660
agctacactg tcgcagtccg ctgctgagcc tcccacactc atctcccctc aagctccagc    720
ctcatcaccc tcatccctat caacctcacc acctgaggtc ttttctgcct ccgttactac    780
caaccatagc tccactgtga ccagcaccca acccactgga gctccaactg caccagagtc    840
cccgacagag gagtccagct ctgaccacac acccacttca catgccacag ctgagccagt    900
accccaggag aaaacacccc caacaactgt gtcaggcaaa gtgatgtgtg agctcataga    960
catggagacc accaccacct ttcccagggt gatcatgcag gaagtagaac atgcattaag   1020
ttcaggcagc atcgccgcca ttaccgtgac agtcattgcc gtggtgctgc tggtgtttgg   1080
agttgcagcc tacctaaaaa tcaggcattc ctcctatgga agacttttgg acgaccatga   1140
ctacgggtcc tggggaaact acaacaaccc tctgtacgat gactcctaac aatggaatat   1200
ggcctgggat gaggattaac tgttctttat ttataagtgc ttatccagta gaattaataa   1260
gtacctgatg cgcattgaac gacaatctta agccctgttt tgttggtatg gttgtttttg   1320
ttttcctccc tctcctctgg ctgctacaac ttcccctttc tggtacaaga agaaccattc   1380
tttaaaggtg agtggaggct gatttgcagc tgaagtgggc cagccttgca ccagccaggc   1440
cagaccacca tggtgaaggc ttctttcccc actgcaggac ccactttgag aaggaccgag   1500
gargaggatt tgggttgttt tgttaggggt tactttcagg ggaacatttc atttgtgtta   1560
tttcttaaac ttctatttag gaaattacat taagtattaa tgaggggaaa ggaaatgagc   1620
tctacgagga tttcaccctg catgggagag agcagggttt tctcagattc ctttttaatc   1680
tctatttatc tggttgtttc tgacaggatg ctgcctgctt ggctctacaa gctggaaagc   1740
agcttcttag ctgcctaatt aatgaaagat gaaaatagga agtgccctgg agggggccag   1800
caggtcacgg ggcagaatct ctcaggttgc tgtgggatct cagtgtgccc ctacctgttc   1860
tcccctccag gccacctgtc tctgtaaagg atgtctgctc tgttcaaaag gcagctggga   1920
tcccagccca caagtgatca gcagagttgc atttccaaag aaaaaggcta tgagatgagc   1980
tgagttatag agagaaaggg agaggcatgt acggtgtggg gaagtggaag agaagctggc   2040
gggggagaag gaggctaacc tgcactgagt acttcattag gacaagtgag aatcagctat   2100
tgataatggc cagagatatc cacagcttgg aggagcccag agaccgtttg ctttataccc   2160
acacagcaac tggtccactg ctttactgtc tgttggataa tggctgtaaa atgtttaaaa   2220
acaaaacaaa acaaaaaaga ggcactagtc tatctgcaat tactcaacga ggcattttca   2280
taggaaacag actatgatta atccatttat tcttcccaca cacttacctt actaagtctt   2340
tgctttaata aatgagcaac cctgggtata gtcttaaaat tctgcacaat aaattttgag   2400
aaagaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagggg gggg                    2444

<210> 1299
<211> 569
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (445)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (538)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (544)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (553)
<223> n equals a,t,g, or c

<400> 1299
ggcggagggc ggtgggacgt gatgcgcggg tcagagccgg gccttgagaa ggaactggag     60
gcccctggca gcggtgtccc ctcgaggacc cctctgccgg gctcaccagg tgtccggctt    120
tgctggccca gcaagcctga taagcatgaa gctcttatct ttggtggctg tggtcgggtg    180
tttgctggtg cccccagctg aagccaacaa gagttctgaa gatatccggt gcaaatgcat    240
ctgtccacct tatagaaaca tcagtgggca catttacaac cagaatgtat cccagaagga    300
ctgcaactgc ctgcacgtgg tggagcccat gccagtgcct ggccatgacg tggargccta    360
ctgcctgctg tgcgagtgca ggtacgagga gcgcagcacc accaccatca aggtcatcat    420
tgtcatctac ctgtccgtgg tgggngccct gttgctctac atggccttcc tgatgctggt    480
ggaccctctg atccgaaagc cggatgcata cactgagcaa ctgcacaatg aggagganaa    540
tgangatgct cgntctatgg caagcagct                                      569

<210> 1300
<211> 2117
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2112)
<223> n equals a,t,g, or c

<400> 1300
cggctcggcs tgcacgccgc tgcccgtacc gccttcagtc aggtggtcgc tagcacgggt     60
gcgcacgcgc aggtctcagg agaggatacc cagcccacga cctacgccgc cgagctcagg    120
ggccaccctg acaccccttg cttctccgca gacctcccag atgttagtca ccagtaagat    180
ggctgccccc gaggctccgg caacctccgc acagtcccag acaggctccc cggcccagga    240
ggctgctact gagggcccta gtagcgcctg tgcwttctct caggctccgt gtgccaggga    300
ggtggacgcc aaccggccca gcacagcctt cctgggccag aatgatgtct tcgatttcac    360
tcagccggca ggtgtcagtg gcatggcctt cccgcgcccc aagagacctg ccccagccca    420
agaggctgcc acagagggcc ccagtgctgc ctctggtgtg ccccagacgg gacctggcag    480
ggaggtggca gccacccggc ccaagaccac caagtcgggg aaggcgctgg ccaagactcg    540
gtgggtggag cctcagaatg ttgtggcagc agctgctgcc aaggccaaga tggccacgag    600
catccctgag ccggagggtg cagctgctgc cactgctcag cacagtgctg agccctgggc    660
caggatggga ggcaagagga ccaagaagtc caagcacctg gatgatgagt atgagagcag    720
cgaggaggag agagagactc ccgcggtccc acccacctgg agagcatcac agccctcatt    780
gacggtgcgg gctcagttgg cccctcggcc cccgatggcc ccgaggtccc agataccctc    840
aaggcacgta ctgtgcctgc ccccccgcaa cgtgaccctt ctgcaggaga gggcaaataa    900
gttggtgaaa tacctgatga ttaaggacta caagaagatc cccatcaagc gcgcagacat    960
gctgaaggat gtcatcagag aatatgatga acatttccct gagatcattg aacgagcaac   1020
gtacaccctg gaaaagaagt ttgggatcca cctgaaggag atcgacaagg aagaacacct   1080
gtatattctt gtctgcacac gggactcctc agctcgcctc cttggaaaaa ccaaggacac   1140
tcccaggctg agtctcctct tggtgattct gggcgtcatc ttcatgaatg gcaaccgtgc   1200
cagcgaggct gtcctctggg aggcactacg caagatggga ctgcgccctg gggtgaggca   1260
cccattcctc ggcgatctga ggaagctcat cacagatgac tttgtgaagc agaagtacct   1320
ggaatacaag aagatcccca acagcaaccc acctgagtat gaattcctct ggggcctgcg   1380
agcccgccat gagaccagca agatgagggt cctgagattc atcgcccaga atcagaaccg   1440
agacccccgg gaatggaagg ctcatttctt ggaggctgtg gatgatgctt tcaagacaat   1500
ggatgtggat atggccgagg aacatgccag ggcccagatg agggcccaga tgaatatcgg   1560
ggatgaagcg ctgattggac ggtggagctg ggatgacata caagtcgagc tcctgacctg   1620
ggatgaggac ggagattttg gcgatgcctg ggccaggatc ccctttgctt tctgggccag   1680
ataccatcag tacattctga atagcaaccg tgccaacagg agggccacgt ggagagctgg   1740
cgtcagcagt ggcaccaatg gaggggccag caccagcgtc ctagatggcc ccagcaccag   1800
ctccaccatc cggaccagaa atgctgccag agctggcgcc agcttcttct cctggatcca   1860
gtaagagttt crgcaccgtt gacgaactgc agcgatctta ctggccaagc cagagcgcct   1920
cctctcagat tccttctcga cacagcaccc taggcggctt cttcctgtca gtcggaggtg   1980
gcatgcaaga tgaagctctc tttgctcttc ctgctttcat tttgtgcttt tccttgtgtt   2040
ttcatgtttt gggtatcagt gttacattaa agttgcaaaa ttaaaaaaaa aaaaaaaact   2100
tggggggggg gnccccg                                                  2117

<210> 1301
<211> 1780
<212> DNA
<213> Homo sapiens

<400> 1301
gcggcagagt cgagagcggc tgcmggrctg cggggcgcct tgactctccc tccaccctgc     60
ctcctcgggc tccactcgtc tgcccctgga ctcccgtctc ctcctgtcct ccggcttccc    120
agagctccct ccttatggca gcagcttccc gcgtctccgg cgcagttctc agcggacgac    180
cctctcgctc cggggctgag cccagtccct ggatgttgct gaaactctcg agatcatgcg    240
cgggtttggc tgctgcttcc ccgccgggtg ccactgccac cgccgccgcc tctgctgccg    300
ccgtccgcgg gatgctcagt agcccgctgc ccggcccccg cgatcctgtg ttcctcggaa    360
gccgtttgct gctgcagagt tgcacgaact agtcatggtg ctgtgggagt ccccgcggca    420
gtgcagcagc tggacacttt gcgagggctt ttgctggctg ctgctgctgc ccgtcatgct    480
actcatcgta gcccgcccgg tgaagctcgc tgctttccct acctccttaa gtgactgcca    540
aacgcccacc ggctggaatt gctctggtta tgatgacaga gaaaatgatc tcttcctctg    600
tgacaccaac acctgtaaat ttgatgggga atgtttaaga attggagaca ctgtgacttg    660
cgtctgtcag ttcaagtgca acaatgacta tgtgcctgtg tgtggctcca atggggagag    720
ctaccagaat gagtgttacc tgcgacaggc tgcatgcaaa cagcagagtg agatacttgt    780
ggtgtcagaa ggatcatgtg ccacagatgc aggatcagga tctggagatg gagtccatga    840
aggctctgga gaaactagtc aaaaggagac atccacctgt gatatttgcc agtttggtgc    900
agaatgtgac gaagatgccg aggatgtctg gtgtgtgtgt aatattgact gttctcaaac    960
caacttcaat cccctctgcg cttctgatgg gaaatcttat gataatgcat gccaaatcaa   1020
agaagcatcg tgtcagaaac aggagaaaat tgaagtcatg tctttgggtc gatgtcaaga   1080
taacacaact acaactacta agtctgaaga tgggcattat gcaagaacag attatgcaga   1140
gaatgctaac aaattagaag aaagtgccag agaacaccac ataccttgtc cggaacatta   1200
caatggcttc tgcatgcatg ggaagtgtga gcattctatc aatatgcagg agccatcttg   1260
caggtgtgat gctggttata ctggacaaca ctgtgaaaaa aaggactaca gtgttctata   1320
cgttgttccc ggtcctgtac gatttcagta tgtcttaatc gcagctgtga ttggaacaat   1380
tcagattgct gtcatctgtg tggtggtcct ctgcatcaca aggaaatgcc ccagaagcaa   1440
cagaattcac agacagaagc aaaatacagg gcactacagt tcagacaata caacaagagc   1500
gtccacgagg ttaatctaaa gggagcatgt ttcacagtgg ctggactacc gagagcttgg   1560
actacacaat acagtattat agacaaaaga ataagacaag agatctacac atgttgcctt   1620
gcatttgtgg taatctacac caatgaaaac atgtactaca gctatatttg attatgtatg   1680
gatatatttg aaatagtata cattgtcttg atgttttttc tgtaatgtaa ataaactatt   1740
tatatcacaa aaaaaaaaaa aaaaaaaaaa aaaaactcga                         1780

<210> 1302
<211> 2694
<212> DNA
<213> Homo sapiens

<400> 1302
gaaagctggt acgcctgcag gtaccggtcc ggaattcccg ggtcgaccca cgcgtccgat     60
ctacatccgc agatatgtgt tcaagcttgg tgtgctaggc tggggggccc cagccctcct    120
ggtgctgctt tccctctctg tcaagagctc ggtatacgga ccctgcacaa tccccgtctt    180
cgacagctgg gagaatggca caggcttcca gaacatgtcc atatgctggg tgcggagccc    240
cgtggtgcac agtgtcctgg tcatgggcta cggcggcctc acgtccctct tcaacctggt    300
ggtgctggcc tgggcgctgt ggaccctgcg caggctgcgg gagcgggcgg atgcaccaag    360
tgtcagggcc tgccatgaca ctgtcactgt gctgggcctc accgtgctgc tgggaaccac    420
ctgggccttg gccttctttt cttttggcgt cttcctgctg ccccagctgt tcctcttcac    480
catcttaaac tcgctctacg gtttcttcct tttcctgtgg ttctgctccc agcggtgccg    540
ctcagaagca gargccaagg cacagataga ggccttcagy tcctyccaaa caacacagta    600
gtccgggcct cctggcctgg aatcctcagc ctctctggcc gccagtagcc tgaggctacg    660
gctcctgcta gagagggtgg caggcctgct gctggacccc agaggccact gtgaccgcca    720
aggggccttt tccacttcca cggcctctcc aggcactgag gggaaggcat tgctctacct    780
ctccctgaca ttttgctccg gggcagatcc aaccttacct ggggcagcaa actttgtcct    840
ggtacctggg cccagctcgc cagggatgtg ggcagagcac cagcctgggc atcaggaagc    900
caagtttcaa ggactgtctt tgagtctgtc tgtatgacct tgggcctgcc acttctcaca    960
gaccctaggt atccacagct gtgacatggg ggcaagcggc tttgtttcag cctaacccag   1020
gagcttagta aaaattgcat aagaccaggg ggaagagtgt cagcgtgggg tgggaattcc   1080
cgcggcctcc acctgcttgc taggggcagg atctcattca ggctgccctg gaagcacctg   1140
cttggccctg ccaccttcct ccaggggagg gccagatggc atcctggctt ggggcgggtg   1200
ggacctaccc aggctctgag actttactgg cctatgcctg aggcctcttt tcctttaact   1260
ccctaaatta tgatgactcc aagtccaagc ccacccttyc caaagawtgg gaggttccgc   1320
cgttcccaga ggctcctcct gcggtgctcc caagacttcc atagaccatc tggaccagta   1380
gcccatcccg cagttttctt gggggcagag gaaaacgctt ctttctcctc cagctgaatc   1440
agctggatcc cagtgtcctg gctgtttggt gattgggcaa gattgaattt gcccaggtag   1500
gcgtgagagt gtgggtttta aattcgaagc tcaggccata gtttcagaga atcaccctta   1560
ccccagacct tcatgagaca gtgctcatga agccagtgcg tttcccagaa cgaacactag   1620
gcggcaccgt tggtccacac tcagaggccc ttggcgccaa gactgcatct agaatcgctc   1680
aaacacctgt ttgcagaccc catgcaccag ctggaggggc cgtaactgca ggactgcgcc   1740
tactgagtga cccatttcct ccaggaggaa aggcaagaca cgcttacacg gccatttgtc   1800
tcttttccca atgcggcggt gcactttcgc tcttgggggc tgcaccccag acatagctgg   1860
caccagagca gggtgctcag gtggtgggtg ctcagggccc tgccccaggc cactgggccg   1920
ttttgatgac ctcgaaggtc acaggcrgaa aataggagca ggatttcccc tggggaaaag   1980
ttctcctggg acatcttctg ctcttctgta catttctaga tgcaaataac tccttcacca   2040
ggcagtgagt ggcgtaggct ctggagccag gctgcctggg ctccaatgcc agctctgcca   2100
cttgctagct gtgagactgt ggacaaacca ctcagcctct gtgtgcctca gttttcctat   2160
ttgtaaaata gaggccatag tggtacctat tttgaagact aagtaaaaga attcaaataa   2220
agagacttgg cacagagtaa gtgctcagta aatggttact ggtattatca ttagtatttt   2280
tgctattatt gttaacagtg ttaactgagt ttcagaggcc agcctgtcta agccccaggc   2340
ccagctctgc tcaaccttgt aggcacaacc ccttcttagg cacatctcac catgcctcag   2400
tttctttccc cagacgggtc tctactccca cctcgctgac tttctgctgt tctaggaata   2460
gtccccacac agtgcagcct ccaggccatg ccacatgtcc cccgacctcc cagttcccca   2520
atcttccggt ctatagaaat tcctggtggt catttatcac atctacaaaa ttgccccagc   2580
ggtgcctaga gaaggcctct ttcccacgct aactccaggc agattctccc cacccctgcc   2640
accatctggg tgatgtgagc acccatcaag cttccatggg taagcccagg cttt         2694

<210> 1303
<211> 2232
<212> DNA
<213> Homo sapiens

<400> 1303
gctgcttcct gcctgggttt ggagttgtca ccactttccc ctctccgtct cctgcgggcg     60
caatggagga ggaggatgag gaagcgcggg cgctcctggc aggcggccct gacgaggccg    120
acagaggtgc cccggccgcc cctggagccc tgccggccct ctgcgacccc agtcgcctgg    180
cgcaccggct tttggtgctg ttactgatgt gcttccttgg ctttggcagc tatttttgct    240
atgataatcc tgctgccctt cagactcaag ttaaacgaga tatgcaagtg aataccacga    300
aattcatgct gctgtatgcc tggtattctt ggcccaatgt agttttgtgt ttctttggtg    360
gctttttgat araccgarta tttggaatac satggggcac aatcattttt agctgctttg    420
tttgcattgg acaggttgtt tttgccctgg gtggaatatt taatgctttt tggctgatgg    480
aatttggaag atttgtattt gggattggtg gcgagtcctt agcagttgcc cagaatacat    540
atgctgtgag ctggtttaaa ggcaaagaat taaacctggt gtttggactt caacttagca    600
tggctagaat tggaagtaca gtaaacatga acctcatggg atggctgtat tctaagattg    660
aagctttgtt aggttctgct ggtcacacaa ccctcgggat cacacttatg attgggggtr    720
taacgtgtat tctttcacta atctgtgcct tggctcttgc ctacttggat cagagagcag    780
agagaatcct tcataaagaa caaggaaaaa caggtgaagt tattaaatta actgatgtaa    840
aggacttctc cttacccctg tggcttatat ttatcatctg tgtctgctat tatgttgctg    900
tgttcccttt tattggactt gggaaagttt tctttacaga gaaatttgga ttttcttccc    960
aggcagcaag tgcaattaac agtgttgtat atgtcatatc agctcccatg tccccggtgt   1020
ttgggctcct ggtggataaa acagggaaga acatcatctg ggttctttgc gcagtagcag   1080
ccactcttgt gtcccacatg atgctggcct ttacgatgtg gaacccttgg attgctatgt   1140
gtcttctggg actctcctac tcattgcttg cctgtgcatt gtggccaatg gtggcatttg   1200
tagttcctga acatcagctg ggaactgcat atggcttcat gcagtccatt cagaatcttg   1260
ggttggccat catttccatc attgctggta tgatactgga ttctcggggg tatttgtttt   1320
tggaagtgtt cttcattgcc tgtgtttctt tgtcactttt atctgtggtc ttactctatt   1380
tggtgaatcg tgcccagggt gggaacctaa attattctgc aagacaaagg gaagaaataa   1440
aattttccca tactgaatga gaagttaaaa tgaatgtgtc atgagaatgg gcttaacaca   1500
tcgttggttt gaaaacttcc atttttaaaa atttagagtt tagtcattag aaaaaataat   1560
ggactggaaa gttatattta tatccaaata tacctatttc aaagtgtatt tgtgaggcct   1620
gttttagcct gtgtcttttg tattgtgtgt tgctaaagaa ttctactttt agtaggctaa   1680
tcaacaatga aagggttaga aaattgctgt ggaacatcca ggtgaacttc aggaaagaca   1740
gtgaaaaatg gaaaacgttg gagcttctgt tgagataatc ttcattaggt atatatctta   1800
gggatacagc cttttcttta tcttatagca ggaaaaaaaa acttttgagg gaaatagaag   1860
ggctgcgtta cacaaaataa acaatggcat tgtcataggc cttcctttta ctagtagggc   1920
ataatgctag ggaatatgtg aagatgtttt tatgaagtct ctttctgatc acgaacaata   1980
gcttgcgctc tactctgtag ttatgtggat tgccgagcaa tgaccctttt caatttctta   2040
tttctgtgtt actgaggacc ctaatcactt agggatgtaa ttttatagta taaactttct   2100
gtacagtttt tcttatagtc taataagtaa aaagtgtcct tcaaattatg ataattgcct   2160
atgtacatgg ataaattaaa acactgcaca cggaaaaaaa aaaaaaaaaa gggcggccgc   2220
tctagaggat cc                                                       2232

<210> 1304
<211> 2386
<212> DNA
<213> Homo sapiens

<400> 1304
gacactatag aaggtacgcc tgcaggtacc ggtccggaat tcccgggtcg acccacgcgt     60
ccgatcagtt atggctaaat cctgtccatc tgtgtgtcgc tgcgatgcgg gtttcattta    120
ctgtaatgat cgctttctga catccattcc aacaggaata ccagaggatg ctacaactct    180
ctaccttcag aacaaccaaa taaataatgc tgggattcct tcagatttga aaaacttgct    240
gaaagtagaa agaatatacc tataccacaa cagtttagat gaatttccta ccaacctccc    300
aaagtatgta aaagagttac atttgcaaga aaataacata aggactatca cttatgattc    360
actttcaaaa attccctatc tggaagaatt acatttagat gacaactctg tctctgcagt    420
tagcatagaa gagggagcat tccgagacag caactatctc cgactgcttt tcctgcccgt    480
aatcacctta gcacaattcc ctggggtttg cccaggacta tagaagaact acgcttggat    540
gataatcgca tatccactat ttcatcacca tctcttcaag gtctcactag tctaaaacgc    600
ctggttctag atggaaacct gttgaacaat catggtttag gtgacaaagt tttcttcaac    660
ctagttaatt tgacagagct gtccctggtg cggaattccc tgactgctgc accagtaaac    720
cttccaggca caaacctgag gaagctttat cttcaagata accacatcaa tcgggtgccc    780
ccaaatgctt tttcttatct aaggcagctc tatcgactgg atatgtccaa taataaccta    840
agtaatttac ctcagggtat ctttgatgat ttggacaata taacacaact gattcttcgc    900
aacaatccct ggtattgcgg gtgcaagatg aaatgggtac gtgactggtt acaatcacta    960
cctgtgaagg tcaacgtgcg tgggctcatg tgccaagccc cagaaaaggt tcgtgggatg   1020
gctattaagg atctcaatgc agaactgttt gattgtaagg acagtgggat tgtaagcacc   1080
attcagataa ccactgcaat acccaacaca gtgtatcctg cccaaggaca gtggccagct   1140
ccagtgacca aacagccaga tattaagaac cccaagctca ctaaggatca acaaaccaca   1200
gggagtccct caagaaaaac aattacaatt actgtgaagt ctgtcacctc tgataccatt   1260
catatctctt ggaaacttgc tctacctatg actgctttga gactcagctg gcttaaactg   1320
ggccatagcc cggcatttgg atctataaca gaaacaattg taacagggga acgcagtgag   1380
tacttggtca cagccctgga gcctgattca ccctataaag tatgcatggt tcccatggaa   1440
accagcaacc tctacctatt tgatgaaact cctgtttgta ttgagactga aactgcaccc   1500
cttcgaatgt acaaccctac aaccaccctc aatcgagagc aagagaaaga accttacaaa   1560
aaccccaatt tacctttggc tgccatcatt ggtggggctg tggccctggt taccattgcc   1620
cttcttgctt tagtgtgttg gtatgttcat aggaatggat cgctcttctc aaggaactgt   1680
gcatatagca aagggaggag aagaaaggat gactatgcag aagctggcac taagaaggac   1740
aactctatcc tggaaatcag ggaaacttct tttcagatgt taccaataag caatgaaccc   1800
atctcgaagg aggagtttgt aatacacacc atatttcctc ctaatggaat gaatctgtac   1860
aaaaacaatc acagtgaaag cagtagtaac cgaagctaca gagacagtgg tattccagac   1920
tcagatcact cacactcatg atgctgaagg actcacagca gacttgtgtt ttgggttttt   1980
taaacctaag ggaggtgatg gtaggaaccc tgttctactg caaaacactg gaaaaagaga   2040
ctgaaaaaaa gcaatgtact gtacatttgc catataattt atatttaaga actttttatt   2100
aaaagtttca aatttcaggt tactgctgcg attgatgtag tggagatgcc tgaacacaat   2160
tctatatttt agtatttttt agtaatttgt actgtatttt ccttgcaaat attggagtta   2220
taaaccattt actttgtgtt ctactgagta agatgacttg ttgactgtga aagtgaattt   2280
tcttgctgtg tcgaacaatc aggactgcat tcatatgaga tccttgtagt ataagcacag   2340
gccatttttc actttggtat taataaaatg taaaaaaaaa attggt                  2386

<210> 1305
<211> 2166
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<400> 1305
acccacgcgg ttnggacccg tggggccggc ttggctagsg cgcggyggcc gtggctaagg     60
ctgctacgaa gcgagcttgg gaggagcagc ggcctgcggg gcagaggagc atcccgtcta    120
ccaggtccca agcggcgtgg cccgcgggtc atggccaaag gagaaggcgc cgagagcggc    180
tccgcggcgg ggctgctacc caccagcatc ctccaaagca ctgaacgccc ggcccaggtg    240
aagaaagaac cgaaaaagaa gaaacaacag ttgtctgttt gcaacaagct ttgctatgca    300
cttgggggag ccccctacca ggtgacgggc tgtgccctgg gtttcttcct tcagatctac    360
ctattggatg tggctcaggt gggccctttc tctgcctcca tcatcctgtt tgtgggccga    420
gcctgggatg ccatcacaga ccccctggtg ggcctctgca tcagcaaatc cccctggacc    480
tgcctgggtc gccttatgcc ctggatcatc ttctccacgc ccctggccgt cattgcctac    540
ttcctcatct ggttcgtgcc cgacttccca cacggccaga cctattggta cctgcttttc    600
tattgcctct ttgaaacaat ggtcacgtgt ttccatgttc cctactcggc tctcaccatg    660
ttcatcagca ccgagcagac tgagcgggat tctgccaccg cctatcggat gactgtggaa    720
gtgctgggca cagtgctggg cacggcgatc cagggacaaa tcgtgggcca agcagacacg    780
ccttgtttcc aggacctcaa tagctctaca gtagcttcac aaagtgccaa ccatacacat    840
ggcaccacct cacacaggga aacgcaaaag gcatacctgc tggcagcggg ggtcattgtc    900
tgtatctata taatctgtgc tgtcatcctg atcctgggcg tgcgggagca gagagaaccc    960
tatgaagccc agcagtctga gccaatcgcc tacttccggg gcctacggct ggtcatgagc   1020
cacggcccat acatcaaact tattactggc ttcctcttca cctccttggc tttcatgctg   1080
gtggagggga actttgtctt gttttgcacc tacaccttgg gcttccgcaa tgaattccag   1140
aatctactcc tggccatcat gctctcggcc actttaacca ttcccatctg gcagtggttc   1200
ttgacccggt ttggcaagaa gacagctgta tatgttggga tctcatcagc agtgccattt   1260
ctcatcttgg tggccctcat ggagagtaac ctcatcatta catatgcggt agctgtggca   1320
gctggcatca gtgtggcagc tgccttctta ctaccctggt ccatgctgcc tgatgtcatt   1380
gacgacttcc atctgaagca gccccacttc catggaaccg agcccatctt cttctccttc   1440
tatgtcttct tcaccaagtt tgcctctgga gtgtcactgg gcatttctac cctcagtctg   1500
gactttgcag ggtaccagac ccgtggctgc tcgcagccgg aacgtgtcaa gtttacactg   1560
aacatgctcg tgaccatggc tcccatagtt ctcatcctgc tgggcctgct gctcttcaaa   1620
atgtacccca ttgatgagga gaggcggcgg cagaataaga aggccctgca ggcactgagg   1680
gacgaggcca gcagctctgg ctgctcagaa acagactcca cagagctggc tagcatcctc   1740
tagggcccgc cacgttgccc gaagccacca tgcagaaggc cacagaaggg atcaggacct   1800
gtctgccggc ttgctgagca gctggactgc aggtgctagg aagggaactg aagactcaag   1860
gaggtggccc aggacacttg ctgtgctcac tgtggggccg gctgctctgt ggcctcctgc   1920
ctcccctctg cctgcctgtg gggccaagcc ctggggctgc cactgtgaat atgccaagga   1980
ctgatcgggc ctagcccgga acactaatgt agaaaccttt tttttacaga gcctaattaa   2040
taacttaatg actgtgtaca tagcaatgtg tgtgtatgta tatgtctgtg agctattaat   2100
gttattaatt ttcataaaag ctggaaagca gctgcctgtt aaaaaaaaaa aaaaaaaaaa   2160
aaaaaa                                                              2166

<210> 1306
<211> 1267
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (132)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1067)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1102)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1128)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1206)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1242)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1243)
<223> n equals a,t,g, or c

<400> 1306
gcggccgcgg caggaggcgg cggcggcggg cgggagcagc ggcggcggcg gcacaggctc     60
ggggccagcc gggcgcgcat ccccgggcgc cctgcgcggt ggagagcttg gcggagctgc    120
gggtgccgca gnacaggagt ggacaaagca agatggcagg gatcttagcc tggttctgga    180
acgaraggtt ttggctcccg cacaatgtca cctgggcgga cctgaagaac acggaggagg    240
ccaccttccc gcargctgag gacctctatc tcgcttttcc cctggccttc tgtatcttca    300
tggtgcggct catcttcgag agatttgtag ccaaaccgtg cgccatagcc ctcaacattc    360
aggccaatgg accacaaatt gctccgccca atgccattct ggaaaaggtc ttcactgcaa    420
ttacaaagca tcctgatgaa aagagattgg aaggcctctc caagcaactg gactgggatg    480
ttcgaagcat tcagcgctgg tttcgacaaa gacgcaatca ggagaagcca agcacgctga    540
cgaggttctg tgagagcatg tggagatttt cattttacct ttatgtattt acctacggag    600
tcagattcct gaaaaagacc ccctggttgt ggaatacgag gcattgctgg tacaactacc    660
cctatcagcc actcacaact gaccttcact actattacat cctggagctg tcgttttatt    720
ggtctttgat gttttctcag ttcactgata tcaaaagaaa ggactttggc attatgttcc    780
tgcaccacct tgtatctawt ttcttgatta ccttttcata tgtcaacaat atggcccgag    840
taggaacgct ggtcctttgt cttcatgatt cagctgatgc tcttctggag gctgycaaaa    900
tggcaaatta tgccaagttt cagaaaatgt gtgatctcct gtttgytatg tttgccgtgg    960
ttttcatcac cacacgactg ggtatatttc ctctctggcc tttgctctgg tgcccagatg   1020
gaaagtgcag tgtaggctta tagctcactg cagccttgaa ctcctgngct caaagtgatc   1080
cttctgcgct caaggggatc tnctggcttc cggcttcttc aagtaacntg gggacctacc   1140
agggcattgt gcctgggcaa caaccccggg tttaaatttt ttaacttttt tgggaagaag   1200
accaangggt cccccaactt attggtttgg cccccaaggg gnngggttcc tttgggaaac   1260
cttccct                                                             1267

<210> 1307
<211> 1098
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1076)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1079)
<223> n equals a,t,g, or c

<400> 1307
ggnnatgaat acgccagcgc gcaattaacc ctcactaaag ggaacaaaag ctggagctcc     60
accgcggtgg cggccgctct agaactagtg gatcccccgg gctgcaggaa ttcggcacga    120
gggaacatcc acatcttctg tactcgtcca ttctgtgtcc ccggggcctg gagtaaagac    180
accttcaaat gcagagactc ttcagattca gctttcctgg aaactgatct tcaatgcact    240
aagagaagga gactctcaaa ccaaaaatga cctggaggca ccatgtcagg cttctgttta    300
cggtcagttt ggcattacag atcatcaatt tgggaaacag ctatcaaaga gagaaacata    360
acggcggtag agaggaagtc accaaggttg ccactcagaa gcaccgacag tcaccgctca    420
actggacctc cagtcatttc ggagaggtga ctgggagcgc cgagggctgg gggccggagg    480
agccgctccc ctactcccgg gctttcggag agggtgcgtc cgcgcggccg cgctgctgca    540
ggaacggcgg tacctgcgtg ctgggcagct tctgcgtgtg cccggcccac ttcaccggcc    600
gctactgcga gcatgaccag aggcgcagtg aatgcggcgc cctggagcac ggagcctgga    660
ccctccgcgc ctgccacctc tgcaggtgca tcttcggggc cctgcactgc ctccccctcc    720
agacgcctga ccgctgtgac ccgaaagact tcctggcctc ccacgctcac gggccgagcg    780
ccgggggcgc gcccagcctg ctactcttgc tgccctgcgc actcctgcac cgcctcctgc    840
gcccggatgc gcccgcgcac cctcggtccc tggtcccttc cgtcctccag cgggagcggc    900
gcccctgcgg aaggccggga cttgggcatc gcctttaatt ttctatgttg taaataatag    960
atgtgtttag tttaccgtaa gctgaagcac tgggtgaata tttttattgg gtaataaata   1020
ttttcatgaa agcgcctttg gctgccagat ccttgggaga gggacacgtg tgtccnagnc   1080
accactgtga ccggtagt                                                 1098

<210> 1308
<211> 1278
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (47)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (59)
<223> n equals a,t,g, or c

<400> 1308
tnngggntct aacggcggga accaatggaa tatctcttaa gctggtncgc ctgcaggtnc     60
cggtccggaa ttcccgggtc gacccacgcg tccgcataaa tactgctcta agaaagggac    120
aggaagtctc agaggctgga gagcagagca ccaagatcgt tctggcagga acagccagtg    180
ggaggttcca gctgagcgct ccccagaggt gagctgatcc ccagccacag cacacaggac    240
caggctgcga gaacagcatc atcagcatca tgctattaca atcccaaacc atgggggttt    300
ctcacagctt tacaccaaag ggcatcacta tccctcaaag agagaaacct ggacacatgt    360
accaaaacga agattacctg cagaacgggc tgccaacaga aaccaccgtt cttgggacwg    420
tccagatcct gtgttgcctg ttgatttcaa gtctgggggc catcttggtt tttgctccct    480
acccctccca cttcaatcca gcaatttcca ccactttgat gtctgggtac ccatttttag    540
gagctctgtg ttttggcatt actggatccc tctcaattat ctctggaaaa caatcaacta    600
agccctttga cctgagcagc ttgacctcaa atgcagtgag ttctgttact gcaggagcag    660
gcctcttcct ccttgctgac agcatggtag ccctgaggac tgcctctcaa cattgtggct    720
cagaaatgga ttatctatcc tcattgcctt attcggagta ctattatcca atatatgaaa    780
tcaaagattg tctcctgacc agtgtcagtt taacaagttc attttcctcg acccagtcac    840
aagatcatat ccaacaggtc aaaaagagtt cttcacggtc ttggatataa gtaactcttg    900
gcctcagagg aaggaaaagc aactcaacac tcatggtcaa gtgtgattag actttcctga    960
aatctctgcc attttagata ctgtgaaaca aactaaaaaa aaaaaagctt ttgttttgta   1020
tttgtttact atgagtcgtt atttaatttc tcttgaaaat aatttcctca aagcccaagt   1080
cartaaatgt tatcagccag tcttccaaaa tggtcataaa ctttataaac tgctttgggt   1140
aaactgagca gaaggtgata cacagaaggg aaaatgtgca ctcatgctag tgtgaatttg   1200
gtaagtygcg tgactctgca ggctgtttct gtattatttt cacactcata ttgcttaaat   1260
attacatatt agggattg                                                 1278

<210> 1309
<211> 1437
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> n equals a,t,g, or c

<400> 1309
gcacgagccg gggccggccg gtctgctcgg gagcgcgccc cgtggcccag ccctgtctcc     60
ttttagcata ggggcttcgg cgccagcggc cagcgctagt cggtctggta aggcaaagcg    120
gagcgnagat cctcaaacgg cctagtgctt cgcgcttccg gagaaaatca gcggtctaat    180
taattcctct ggtttgttga agcagttacc aagaatcttc aaccctttcc cacaaaagct    240
aattgagtac acgttcctgt tgagtacacg ttcctgttga tttacaaaag gtgcaggtat    300
gagcaggtct gaagactaac attttgtgaa gttgtaaaac agaaaacctg ttagaaatgt    360
ggtggtttca gcaaggcctc agtttccttc cttcagccct tgtaatttgg acatctgctg    420
ctttcatatt ttcatacatt actgcagtaa cactccacca tatagacccg gctttacctt    480
atatcagtga cactggtaca gtagctccag aaaaatgctt atttggggca atgctaaata    540
ttgcggcagt tttatgcatt gctaccattt atgttcgtta taagcaagtt catgctctga    600
gtcctgaaga gaacgttatc atcaaattaa acaaggctgg ccttgtactt ggaatactga    660
gttgtttagg actttctatt gtggcaaact tccagaaaac aacccttttt gctgcacatg    720
taagtggagc tgtgcttacc tttggtatgg gctcattata tatgtttgtt cagaccatcc    780
tttcctacca aatgcagccc aaaatccatg gcaaacaagt cttctggatc agactgttgt    840
tggttatctg gtgtggagta agtgcactta gcatgctgac ttgctcatca gttttgcaca    900
gtggcaattt tgggactgat ttagaacaga aactccattg gaaccccgag gacaaaggtt    960
atgtgcttca catgatcact actgcagcag aatggtctat gtcattttcc ttctttggtt   1020
ttttcctgac ttacattcgt gattttcaga aaatttcttt acgggtggaa gccaatttac   1080
atggattaac cctctatgac actgcacctt gccctattaa caatgaacga acacggctac   1140
tttccagaga tatttgatga aaggataaaa tatttctgta atgattatga ttctcaggga   1200
ttggggaaag gttcacagaa gttgcttatt cttctctgaa attttcaacc acttaatcaa   1260
ggctgacagt aacactgatg aatgctgata atcaggaaac atgaaagaag ccatttgata   1320
gattattcta aaggatatca tcaagaagac tattaaaaac acctatgcct atactttttt   1380
atctcagaaa ataaagtcra aagactatga aaaaaaaaaa aaaaaaaaaa ctcgtag      1437

<210> 1310
<211> 793
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (56)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (734)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (771)
<223> n equals a,t,g, or c

<400> 1310
gcgggcgggg gcgtggcggg gcggccgcnt cggttggcga ggtcactgca ggtcanaggt     60
cacgagatca aggatctgga accctgaggt gtgcacagcg ctgggatgcc aggttcggcc    120
tcgaagcgga ggatccctgt gtcccagccg ggcatggccg acccccacca gcttttcgat    180
gacacaagtt cagcccagag ccggggctat ggggcccagc gggcacctgg tggcctgagt    240
tatcctgcag cctctcccac gccccatgca gccttcctgg ctgacccggt gtccaacatg    300
gccatggcct atgggagcag cctggccgcg cagggcaagg agctggtgga taagaacatc    360
gaccgcttca tccccatcac caagctcaag tattactttg ctgtggacac catgtatgtg    420
ggcagaaagc tgggcctgct gttcttcccc tacctacacc aggactggga agtgcagtac    480
caacaggaca ccccggtggc cccccgcttt gacgtcaatg ccccggacct ctacattcca    540
gcaatggctt tcatcaccta cgttttggtg gctggtcttg cgctggggac ccaggatagg    600
ttctccccag acctcctggg gctgcaagcg agctyagccc tggcctggct gaccctggar    660
gtgctggcca tcctgstyar cctytatytt gggtcaaytg gtaaaaaccg gaacttcacc    720
accattcgaa cctngggggg gccttttttg gggcttacca aataatggtc ngggaatgaa    780
attgggcggg ggg                                                       793

<210> 1311
<211> 3138
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2081)
<223> n equals a,t,g, or c

<400> 1311
gccggttcng gaaatttccc cggggtcgac ccacgygtcc gccgaagttg gtctgaaggc     60
aagggcttgt tggttgtgga cagcactttg tcatgggacc tgtacggttg gggatgttgc    120
ttttcatttt ggctgtgtat ggcgcttggg ttgcgacgcc gaaggaggaa gacgatgaca    180
cagaacgctt gcccagcaaa tgtgaagtgt gtaagttgct gagcctggag ctgcaggaaa    240
agctgagtcg cactggccga tctcgagagg tgctggagct ggggcaggtg ctagacactg    300
gcaagagaaa gaggcacatc ccctacagtg tttcagagac aaggctggaa gaggccttgg    360
agaatttgtg tgaccggatc ctggactaca gtgttcatgc tgagcgcaag ggctcactga    420
gatatgccaa gggtcagagt cagaccatgg caacgctgaa aggtctggtg cagaaggggg    480
tgaaggtgga tctggggatc cctctggagc tgtgggacga gcccagcgtg gaagtcacat    540
tcctcaagaa gcagtgtgag acaatgctgg aggagtttga agatgtcgtg ggagactggt    600
acttccatca tcaggaacag ccgttacagc attttctctg tgaaggtcat gtgctccccc    660
ctgctgaaac tgcatgtcta caggaaactt ggactggaaa ggaaaagatc acggatgggc    720
aagagaagac agaaggggag gaggaacacg atcaggagga ggaagaagag gaagaggagg    780
aagagaggat caacacacca gggcactcca agcatgaccc tgaggatctc tgactcttgc    840
ctttgagccc ccaggagggg caggagtcat ggagaagaac cctctgaaat ctgagctctc    900
tgtgctccac ataagggcat gtgtgtatgt gtgagtgatc ccaccccgga gcttgtagct    960
gttctcacct gtctggtctc aggtaggatc ctagtggtgc agcatagcaa ggctatgggg   1020
acaaaaccag gaacaggagg cagaaggcct gcttcaaccg atgagtcctc tgcctgccac   1080
agagcccctt aactggcagg tgtgtgtgtg tggtgacaat gctgaaggct ttccccttta   1140
aatctctcta ctacttccca ccccacccag aggtcagtga agccattgga cctatgggtc   1200
taaggcgaaa ggcactttgt ccttcgggtc cgtttttaga tccctacaag gaagaagcca   1260
gcttggacat tctctacgac ctatacacac cgcctgcgtc aaggctacaa cccaagaaac   1320
tgaacaaaaa aggggacact atgaagatgg ggcaatgatg ttaagttagg tggggtagat   1380
attcggtcta cttcatacaa atatcaccga gggcccacca tgtaatttca caggtgccaa   1440
attttctaca ttgctagtaa attttttaaa acatcacctg ggcccctagt ttcaaacaac   1500
ttccctgcac acttcatacc tggccgatat agcagcgccc agagaatggg gccgttcgtc   1560
gcccgctgtt ggaagctaat ggtggtttgt aatttgcagt ccagggaggc tggcaggggt   1620
gccccggctg ataaccattt aggcgcgggg cagtgccagg ctctcggcgc gtgcggggga   1680
aggcaccgga attaagagac cgcgtccggc agcgcgtctc ggccaccatc ctccgggttt   1740
acgggagctc gcagaggaca aaatttctcg cgcttttccg gggggcggag ctaacctggc   1800
agggagggaa ggattaggag aagcggtgac actaggtcca aggcgggaag cgcctcggtt   1860
agattgaggg aaataaagag gatgtccttt gtgggatgat gggtgaggac ctaccacaag   1920
agaagcgtgg cgaaggccga aaaccgaggg aatggcgggg ttcgcgctaa gggaagcttg   1980
gacgagacca tctacggata gggggttagg gcgataccat cttgagggag ttagggggtg   2040
gcaaagaaca gccgtggaag gtgctacttg gaggaggcgg ngcgcacgtg ggaacccaaa   2100
gagactgggc cgtcgcctac atccgcactt cccttcccca gccgtcccga tcctgccatg   2160
agcgctgcgg tgcggaccga gccgctgcgc ggggagccgc ctctgctggt gcgcggcgac   2220
ccctactcgg tggtggtcct gcttcagggc tacgcggagc cggagggggt cgacgacgcg   2280
gtacgcgccg acggctccgt gacgcttgtg ctgcctcagg cctggggctc agccaccagc   2340
ctycaagagt ccccgcccca cagcggcggg gcgaagaccg ccctggaaga ggcggcccgt   2400
ggccccatcc tcgtggacac tgggggcccc tgggctcggg aggcgctcct gggggccctg   2460
gcggggcagg gcatggcccc tggagacgtg acgctggtgg tgggcaccca cggacactcg   2520
gatcacatcg ggaacctggg gctttttcct ggggcggctc tgctggtctc gcacgacttc   2580
tgcctgcccg gaggccgcta cctcccccac gggctaggtg aggagcggcc cctgcagctg   2640
ggccccgggc tcgaggtgtg ggccacgccg ggccatgggg gccagcggga cgtgagcgtg   2700
gtggtggcgg gcacggccct gggcaccgtg gtggtggcag gcgacgtgtt tgaacgcagc   2760
ggagacgaag actcatggca agcgctgagc gaagacccgg tggcccagga gcggagccgg   2820
aagagggtcc tagatactgc ggacgtagtc gtgcctggtc acggagcccc ctttaggggg   2880
tcagagaagc ccctcagcca cggaaytgat gtccagaaga ccagaggtca gtgtgatcgm   2940
ttccagcccc cttgcaagag gccggttttc cagcgaggac agtcatctct atcactggtt   3000
ctgcaaccaa actaggacca aagactggct cagccgtgtg ccacctctca gggtcccccg   3060
taaagtagga gaatgttctt gggagggtcg tccaaaataa aaataggcaa ctgcatagaa   3120
aaaaaaaaaa aaaaaaag                                                 3138

<210> 1312
<211> 1871
<212> DNA
<213> Homo sapiens

<400> 1312
taatcaaagc tcaggaggag agctgcattc cactgtttca cagatgctgt gagggtgaca     60
aagatgcagg gcacccactg gaaacacaga cggcactctg cgaaagagga aggggcgcca    120
ggagcttggg tgagcaaggt tggaggtgat tctgcccctc tccccaggct ttctgtatta    180
gaaaactgaa gcttcaagaa cagacttgcc taacaacagg aaacttgtat gtctcgaagt    240
ggcaattcac acataaggct ccatgactcc tgaactctca caaatattag ttggctcttt    300
tcatggtttt actgaagttg ctagaagttt acagaaaagg aagtgcagga acatttcaca    360
aatctacaat ctgtgagtat cacatcctgt atagctgtaa acactggaat aaggaagggc    420
tgatgacttt cagaagatga aggtaagtag aaaccgttga tgggactgag aaaccagagt    480
taaaacctct ttggagcttc tgaggactca gctggaacca acgggcacag ttggcaacac    540
catcatgaca tcacaacctg ttcccaatga gaccatcata gtgctcccat caaatgtcat    600
caacttctcc caagcagaga aacccgaacc caccaaccag gggcaggata gcctgaagaa    660
acatctacac gcagaaatca aagttattgg gactatccag atcttgtgtg gcatgatggt    720
attgagcttg gggatcattt tggcatctgc ttccttctct ccaaatttta cccaagtgac    780
ttctacactg ttgaactctg cttacccatt cataggaccc ttttttttta tcatctctgg    840
ctctctatca atcgccacag agaaaaggtt raccaagctt ttggtgcata gcagcctggt    900
tggaagcatt ctgagtgctc tgtctgccct ggtgggtttc attatcctgt ctgtcaaaca    960
ggccacctta aatcctgcct cactgcagtg tgagttggac aaaaataata taccaacaag   1020
aagttatgtt tcttactttt atcatgattc actttatacc acggactgct atacagccaa   1080
agccagtctg gctggawctc tctctctgat gctgatttgc actctgctgg aattctgcct   1140
agctgtgctc actgctgtgc tgcggtggaa acaggcttac tctgacttcc ctgggagtgt   1200
acttttcctg cctcacagtt acattggtaa ttctggcatg tcctcaaaaa tgactcatga   1260
ctgtggatat gaagaactat tgacttctta agaaaaaagg gagaaatatt aatcagaaag   1320
ttgattctta tgataatatg gaaaagttaa ccattataga aaagcaaagc ttgagtttcc   1380
taaatgtaag cttttaaagt aatgaacatt aaaaaaaacc attatttcac tgtcatttaa   1440
gatatgtgtt cattggggat ctcttgattt gcctgacatt gacttcagca aaagcacggg   1500
gctgtaaatt accatttact agattagcca aatagtctga atttccagaa aacaaggcag   1560
aatgatcatt cccagaaaca tttcccagaa aatgtttccc agaaaactag acagmatgat   1620
cattcaatgg atcacagtga agcaaaggac acaacttttt attgtacccc ttaattgtca   1680
acaggagtta actgatttgt tgtggtgctc agactttttt atacaggtgc tagtgtttta   1740
tcctatgtat tttaactcat tagtgcataa aggcaagccc catataatga agtctcaggg   1800
tatatgaaag tagctggctt caaaataaaa tttttgagtg caaaaaaaaa aaaaaataaa   1860
aaaaaaaaaa a                                                        1871

<210> 1313
<211> 1894
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1878)
<223> n equals a,t,g, or c

<400> 1313
ctctaatacg actcactata gggaaagctg gtacgcctgc aggtaccggt ccggaattcc     60
cgggtcgacc cacgcgtccg ggatgacact gggcccccca tggacaagtc tgatctgggc    120
cagaagcgga cttcgggggc tgtctgccac caggacccca ggacctgcga ggagccagcc    180
tccagcggtg cccacatctg gcccgatgac atcactaagt ggccgatctg cacagagcag    240
gccaggagca accacacagg cttcctgcac gtggactgcg agatcaaggg ccgcccctgc    300
tgcatcggca ccaagggcag ctgtgagatc accacccggg aatactgtga gttcatgcac    360
ggctatttcc atgaggaagc aacactctgc tcccaggtgc actgcttgga caaggtgtgt    420
gggctgctgc ccttcctcaa ccctgaggtc ccagatcagt tctacaggct ctggctgtct    480
ctcttcctac atgctggcgt ggtgcactgc ctcgtgtctg tggtctttca aatgaccatc    540
ctgagggacc tggagaagct ggccggctgg caccgtatcg ccatcatctt catcctcagt    600
ggcatcacag gcaacctcgc cagtgccatc tttctcccat accgggcaga ggtgggcccg    660
gccggctcac agttcggcct cctcgcctgc ctcttcgtgg agctcttcca gagctggccg    720
ctgctggaga ggccctggaa ggccttcctc aacctctcgg ccatcgtgct cttcctgttc    780
atctgtggcc tcctgccctg gatcgacaac atcgcccaca tcttcggctt cctcagtggc    840
ctgctgctgg ccttcgcctt cctgccctac atcaccttcg gcaccagcga caagtaccgc    900
aagcgggcac tcatcctggt gtcactgctg gcctttgccg gcctcttcgc cgccctcgtg    960
ctgtggctgt acatctaccc cattaactgg ccctggatcg agcacctcac ctgcttcccc   1020
ttcaccagcc gcttctgcga gaagtatgag ctggaccagg tgctgcactg accgctgggc   1080
cacacggctg cccctcagcc ctgctggaac agggtctgcc tgcgagggct gccctctgca   1140
gagcgctctc tgtgtgccag agagccagag acccaagaca gggcccgggc tctggacctg   1200
ggtgcccccc tgccaggcga ggctgactcc gcgtgagatg gttggttaag gcggggtttt   1260
tctggggcgt gaggcctgtg agatcctgac ccaagctcag gcacacccaa ggcacctgcc   1320
tctctgagtc ttgggtctca gttcctaata tcccgctcct tgctgagacc atctcctggg   1380
gcagggtcct tttcttccca ggtcctcagc gctgcctctg ctggtgcctt ctcccccact   1440
actactggag cgtgcccttg ctggggacgt ggctgtgccc tcagttgccc ccagggctgg   1500
gtgcccacca tgccccttcc tctttctcct cctacctctg ccctgtgagc ccatccataa   1560
ggctctcaga tgggacattg tgggaaaggc tttggccatg gtctgggggc agagaacaag   1620
gggggagaca caagtagacc tcaggtagaa cgacactggg cggagccacc ccagggcctg   1680
ctcccaggga gtgctcgagg cgcatcaggc ccgtttttta ccagtttata tcacggtctt   1740
catttttaaa agtaacgcta actttgtasg gacgatgtct catggattaa ataatattct   1800
ttatggcagt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaactc gagggggggc   1860
ccggwaccca aatcgacnaa tagtgagtca taaa                               1894

<210> 1314
<211> 736
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (4)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (6)
<223> n equals a,t,g, or c

<400> 1314
nttnnnatgm atcgccggct cgaaataacc ctactaaagg gaacaaaagc tggagctcca     60
ccgcggtggc ggccgctcta gaactagtgg atcccccggg ctgcaggaat tcggcacgag    120
caactcatgg agcccccccg ggcccatcga gtaccggact ggctgacccc ctagggttgg    180
cagtagcccc tgaccctcag tatggccaac actaccggag agcctgagga ggtgagcggc    240
gctctgtccc caccgtccgc atcagcttat gtgaagctgg tactgctggg actgattatg    300
tgcgtgagcc tggcgggtaa cgccatcttg tccctgctgg tgctcaagga gcgtgccctg    360
cacaaggctc cttactactt cctgctggac ctgtgcctgg ccgatggcat acgctctgcc    420
gtctgcttcc cctttgtgct ggcttctgtg cgccacggct cttcatggac cttcagtgca    480
ctcagctgca agattgtggc ctttatggcc gtgctctttt gcttccatgc ggccttcatg    540
ctgttctgca tcagcgtcac ccgctacatg gccatcgccc accaccgctt ctacgccaag    600
cgcatgacac tctggacatg cgcggctgtc atctgcatgg cctgaccctg tctgtggcca    660
tggccttccc acctgtcttt gacgtgggca cctycaagtt tattcgggag gaggacaagt    720
gcatctttga gcatcc                                                    736

<210> 1315
<211> 1553
<212> DNA
<213> Homo sapiens

<400> 1315
cgcctgcagg taccggtccg gaattcccgg gtcgacccac kcgtcmkggc gaccgagcag     60
aggcctttcc acctggtggt gttcggcgcg tctggcttca ccggccagtt cgtgaccgag    120
gaggtggccc gggagcaggt ggacccggag cggagctccc gcctgccctg ggccgtggcg    180
ggccgctccc gggagaagct gcagcgggtg ctggagaagg cggccctgaa gctgggaaga    240
ccaacactgt catctgaagt tggaatcatc atctgtgata ttgctaatcc agcctcgctt    300
gatgaaatgg ctaaacaggc aacagttgtc ctcaattgcg taggaccata tcggttttat    360
ggagaacctg taataaaagc atgtattgaa aatggagcca gttgtatcga catcagtgga    420
gaacctcagt ttctggaact aatgcaactg aagtatcatg agaaagctgc agacaaaggg    480
gtttatatca ttggaagcag cggctttgac tccattccag cagatctggg agtaatatat    540
accagaaata aaatgaatgg tactttgact gctgtggaaa gtttcctgac tatacattca    600
ggacctgagg ggttgagcat tcatgatggt acctggaagt cagcaattta tggttttgga    660
gatcagagta atttgagaaa actaagaaat gtatcaaatc tgaaacctgt cccgctcatt    720
ggtccaaaat tgaagagaag gtggccaatt tcttattgtc gggaactcaa aggttattcc    780
attcctttta tgggatctga tgtgtctgtt gtaaggagga ctcaacgtta cttgtatgaa    840
aatttagagg aatcaccagt tcagtatgct gcgtatgtaa ctgtgggagg catcacctct    900
gttattaagc tgatgtttgc aggacttttc tttttgttct ttgtgaggtt tggaattgga    960
aggcaacttc tcataaaatt cccatggttc ttctcctttg gctatttttc aaaacaaggc   1020
ccaacacaaa aacagattga tgctgcctca ttcacgctga cattctttgg tcaaggatac   1080
agccaaggca ctggtacaga taagaacaaa ccaaatatca aaatttgtac tcaggtgaaa   1140
ggaccagagg ctggctatgt ggctaccccc atagctatgg ttcaggcagc catgactctt   1200
ctaagtgatg cttctcatct gcctaaggcg ggcggggtct tcacacctgg agcagctttt   1260
tccaaaacaa agttgattga cagactcaac aaacacggta ttgagtttag tgttattagc   1320
agctctgaag tctaaacact ggaagaatta actgaagtca taacgtgcgt gaattaacag   1380
cttctctatt tgatatttga aattcttctg taagcctgtc tgagtgtatg tggaaacgat   1440
tgtcaaatct aaaatatcta tatattaaaa agtaggaaat tgtcctagct taccctaaat   1500
ttcaaaaaaa aaaaaaaaaa cccgcaaggg ggggcccggt ccccaatccc ccc          1553

<210> 1316
<211> 931
<212> DNA
<213> Homo sapiens

<400> 1316
ctactactac taaattcgcg gccggtcgac gctggtgcac aggaaggatg aggaagacca     60
ggctctgggg gctgctgtgg atgctctttg tctcagaact ccgagctgca actaaattaa    120
ctgaggaaaa gtatgaactg aaagaggggc agaccctgga tgtgaaatgt gactacacgc    180
tagagaagtt tgccagcagc cagaaagctt ggcagataat aagggacgga gagatgccca    240
agaccctggc atgcacagag aggccttcaa agaattccca tccagtccaa gtggggagga    300
tcatactaga agactaccat gatcatggtt tactgcgcgt ccgaatggtc aaccttcaag    360
tggaagattc tggactgtat cagtgtgtga tctaccagcc tcccaaggag cctcacatgc    420
tgttcgatcg catccgcttg gtggtgacca agggtttttc agggacccct ggctccaatg    480
agaattctac ccagaatgtg tataagattc ctcctaccac cactaaggcc ttgtgcccac    540
tctataccag ccccagaact gtgacccaag ctccacccaa gtcaactgcc gatgtctcca    600
ctcctgactc tgaaatcaac cttacaaatg tgacagatat catcagggtt ccggtgttca    660
acattgtcat tctcctggct ggtggattcc tgagtaagag cctggtcttc tctgtcctgt    720
ttgctgtcac gctgaggtca tttgtaccct aggcccacga acccacgaga atgtcctctg    780
acttccagcc acatccatct ggcagttgtg ccaagggagg agggaggagg taaaaggcag    840
ggagttaata acatgaatta aatctgtaat caccrgctaa aaaaaaaaaa aaaaaaaaaa    900
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa c                                   931

<210> 1317
<211> 2633
<212> DNA
<213> Homo sapiens

<400> 1317
gggcatccag agtacgggtc gagcccgggc catggagccc ccctggggag gcggcaccag     60
ggagcctggg cgcccggggc tccgccgcga ccccatcggg tagaccacag aagctccggg    120
acccttccgg cacctctgga cagcccagga tgctgttggc caccctcctc ctcctcctcc    180
ttggaggcgc tctggcccat ccagaccgga ttatttttcc aaatcatgct tgtgaggacc    240
ccccagcagt gctcttagaa gtgcagggca ccttacagag gcccctggtc cgggacagcc    300
gcacctcccc tgccaactgc acctggctca tcctgggcag caaggaacag actgtcacca    360
tcaggttcca gaagctacac ctggcctgtg gctcagagcg cttaacccta cgctcccctc    420
tccagccact gatctccctg tgtgaggcac ctcccagccc tctgcagctg cccgggggca    480
acgtcaccat cacttacagc tatgctgggg ccagagcacc catgggccag ggcttcctgc    540
tctcctacag ccaagattgg ctgatgtgcc tgcaggaaga gtttcagtgc ctgaaccacc    600
gctgtgtatc tgctgtccag cgctgtgatg gggttgatgc ctgtggcgat ggctctgatg    660
aagcaggttg cagctcagac cccttccctg gcctgacccc aagacccgtc ccctccctgc    720
cttgcaatgt caccttggag gacttctatg gggtcttctc ctctcctgga tatacacacc    780
tagcctcagt ctcccacccc cagtcctgcc attggctgct ggacccccat gatggccggc    840
ggctggccgt gcgcttcaca gccctggact tgggctttgg agatgcagtg catgtgtatg    900
acggccctgg gccccctgag agctcccgac tactgcgtag tctcacccac ttcagcaatg    960
gcaaggctgt cactgtggag acactgtctg gccaggctgt tgtgtcctac cacacagttg   1020
cttggagcaa tggtcgtggc ttcaatgcca cctaccatgt gcggggctat tgcttgcctt   1080
gggacagacc ctgtggctta ggctctggcc tgggagctgg cgaaggccta ggtgagcgct   1140
gctacagtga ggcacagcgc tgtgacggct catgggactg tgctgacggc acagatgagg   1200
aggactgccc aggctgccca cctggacact tcccctgtgg ggctgctggc acctctggtg   1260
ccacagcctg ctacctgcct gctgaccgct gcaactacca gactttctgt gctgatggag   1320
cagatgagag acgctgtcgg cattgccagc ctggcaattt ccgatgccgg gacgagaagt   1380
gcgtgtatga gacgtgggtg tgcgatgggc agccagactg tgcggacggc agtgatgagt   1440
gggactgctc ctatgttctg ccccgcaagg tcattacagc tgcagtcatt ggcagcctag   1500
tgtgcggcct gctcctggtc atcgccctgg gctgcacctg caagctctat gccattcgca   1560
cccaggagta cagcatcttt gcccccctct cccggatgga ggctgagatt gtgcagcagc   1620
aggcaccccc ttcctacggg cagctcattg cccagggtgc catcccacct gtagaagact   1680
ttcctacaga gaatcctaat gataactcag tgctgggcaa cctgcgttct ctgctacaga   1740
tcttacgcca ggatatgact ccaggaggtg gcccaggtgc ccgccgtcgt cagcggggcc   1800
gcttgatgcg acgcctggta cgccgtctcc gccgctgggg cttgctccct cgaaccaaca   1860
ccccggctcg ggcctctgag gccagatccc aggtcacacc ttctgctgct ccccttgagg   1920
ccctagatgg tggcacaggt ccagcccgtg agggcggggc agtgggtggg caagatgggg   1980
agcaggcacc cccactgccc atcaaggctc ccctcccatc tgctagcacg tctccagccc   2040
ccactactgt ccctgaagcc ccagggccac tgccctcact gcccctagag ccatcactat   2100
tgtctggagt ggtgcaggcc ctgcgaggcc gcctgttgcc cagcctgggg cccccaggac   2160
caacccggag cccccctgga ccccacacag cagtcctggc cctggaagat gaggacgatg   2220
tgctactggt gccactggct gagccggggg tgtgggtagc tgaggcagag gatgagccac   2280
tgcttacctg aggggacctg ggggctctac tgaggcctct cccctggggg ctctactcat   2340
agtggcacaa ccttttagag gtgggtcagc ctcccctcca ccacttcctt ccctgtccct   2400
ggatttcagg gacttggtgg gcctcccgtt gaccctatgt agctgctata aagttaagtg   2460
tccctcaggc agggagaggg ctcacagagt ctcctctgta cgtggccatg gccagacacc   2520
ccagtccctt caccaccacc tgctccccac gccaccacca tttgggtggc tgtttttaaa   2580
aagtaaagtt cttagaggat mawaaaaaaa aaaaaaaaaa aaaaaaaaaa agg          2633

<210> 1318
<211> 5459
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3960)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (3961)
<223> n equals a,t,g, or c

<400> 1318
accaattccc ttcctgggag ttgcggcttc cctcgctcgg ccccactccc gtttaccctt     60
tccccagctc ccgccttagc caggggcttc cccgcctgcc gctagggctc gggccgaagc    120
gccgctcagc gccagcctgc cgctccccgg gctccacttt cactttcggt cctgggggar    180
ctargccggm ggcagtggtg gtggcggcgg cgcaagggtg agggcggccc cagaacccca    240
ggtaggtaga gcaagaagat ggtgtttctg cccctcaaat ggtcccttgc aaccatgtca    300
tttctacttt cctcactgtt ggctctctta actgtgtcca ctccttcatg gtgtcagagc    360
actgaagcat ctccaaaacg tagtgatggg acaccatttc cttggaataa aatacgactt    420
cctgagtacg tcatcccagt tcattatgat ctcttgatcc atgcaaacct taccacgctg    480
accttctggg gaaccacgaa agtagaaatc acagccagtc agcccaccag caccatcatc    540
ctgcatagtc accacctgca gatatctagg gccaccctca ggaagggagc tggagagagg    600
ctatcggaag aacccctgca ggtcctggaa cacccccctc aggagcaaat tgcactgctg    660
gctcccgagc ccctccttgt cgggctcccg tacacagttg tcattcacta tgctggcaat    720
ctttcggaga ctttccacgg attttacaaa agcacctaca gaaccaagga aggggaactg    780
aggatactag catcaacaca atttgaaccc actgcagcta gaatggcctt tccctgcttt    840
gatgaacctg ccttcaaagc aagtttctca atcaaaatta gaagagagcc aaggcaccta    900
gccatctcca atatgccatt ggtgaaatct gtgactgttg ctgaaggact catagaagac    960
cattttgatg tcactgtgaa gatgagcacc tatctggtgg ccttcatcat ttcagatttt   1020
gagtctgtca gcaagataac caagagtgga gtcaaggttt ctgtttatgc tgtgccagac   1080
aagatgaatc aagcagatta tgcactggat gctgcggtga ctcttctaga attttatgag   1140
gattatttca gcataccgta tcccctaccc aaacaagatc ttgctgctat tcccgacttt   1200
cagtctggtg ctatggaaaa ctggggactg acaacatata gagaatctgc tctgttgttt   1260
gatgcagaaa agtcttctgc atcaagtaag cttggcatca caatgactgt ggcccatgaa   1320
ctggcccacc agtggtttgg gaacctggtc actatggaat ggtggaatga tctttggcta   1380
aatgaaggat ttgccaaatt tatggagttt gtgtctgtca gtgtgaccca tcctgaactg   1440
aaagttggag attatttctt tggcaaatgt tttgacgcaa tggaggtaga tgctttaaat   1500
tcctcacacc ctgtgtctac acctgtggaa aatcctgctc agatccggga gatgtttgat   1560
gatgtttctt atgataaggg agcttgtatt ctgaatatgc taagggagta tcttagcgct   1620
gacgcattta aaagtggtat tgtacagtat ctccagaagc atagctataa aaatacaaaa   1680
aacgaggacc tgtgggatag tatggcaagt atttgcccta cagatggtgt aaaagggatg   1740
gatggctttt gctctagaag tcaacattca tcttcatcct cacattggca tcaggaaggg   1800
gtggatgtga aaaccatgat gaacacttgg acactgcaga ggggttttcc cctaataacc   1860
atcacagtga gggggaggaa tgtacacatg aagcaagagc actacatgaa gggctctgac   1920
ggcgccccgg acactgggta cctgtggcat gttccattga cattcatcac cagcaaatcc   1980
gacatggtcc atcgattttt gctaaaaaca aaaacagatg tgctcatcct cccagaagag   2040
gtggaatgga tcaaatttaa tgtgggcatg aatggctatt acattgtgca ttacgaggat   2100
gatggatggg actctttgac tggcctttta aaaggaacac acacagcagt cagcagtaat   2160
gatcgggcaa gtctcattaa caatgcattt cagctcgtca gcattgggaa gctgtccatt   2220
gaaaaggcct tggatttatc cctgtacttg aaacatgaaa ctgaaattat gcccgtgttt   2280
caaggtttga atgagctgat tcctatgtat aagttaatgg agaaaagaga tatgaatgaa   2340
gtggaaactc aattcaaggc cttcctcatc aggctgctaa gggacctcat tgataagcag   2400
acatggacag acgagggctc agtctcagag cgaatgctgc ggagtgaact actactcctc   2460
gcctgtgtgc acaactatca gccgtgcgta cagagggcag aaggctattt cagaaagtgg   2520
aaggaatcca atggaaactt gagcctgcct gtcgacgtga ccttggcagt gtttgctgtg   2580
ggggcccaga gcacagaagg ctgggatttt ctttatagta aatatcagtt ttctttgtcc   2640
agtactgaga aaagccaaat tgaatttgcc ctctgcagaa cccaaaataa ggaaaagctt   2700
caatggctac tagatgaaag ctttaaggga gataaaataa aaactcagga gtttccacaa   2760
attcttacac tcattggcag gaacccagta ggatacccac tggcctggca atttctgagg   2820
aaaaactgga acaaacttgt acaaaagttt gaacttggct catcttccat agcccacatg   2880
gtaatgggta caacaaatca attctccaca agaacacggc ttgaagaggt aaaaggattc   2940
ttcagctctt tgaaagaaaa tggttctcag ctccgttgtg tccaacagac aattgaaacc   3000
attgaagaaa acatcggttg gatggataag aattttgata aaatcagagt gtggctgcaa   3060
agtgaaaagc ttgaacgtat gtaaaaattc ctcccttgcc aggttcctgt tatctctaat   3120
caccaacatt ttgttgagtg tattttcaaa ctagagatgg ctgttttggc tccaactgga   3180
gatacttttt tcccttcaac tcattttttg actatccctg tgaaaagaat agctgttagt   3240
ttttcatgaa tgggcttttt catgaatggg ctatcgctac catgtgtttt gttcatcaca   3300
ggtgttgccc tgcaacgtaa acccaagtgt tgggttccct gccacagaag aataaagtac   3360
cttattcttc tcattttata gtttatgctt aagcacccgt gtccaaaacc ctgtacccca   3420
tgtttatmat tcataaactg tttcatcagt ctcctcgaaa gactctgaat agtcgactac   3480
tgaacaatga acacctggat ctgagactaa gccggacgat gactgggtta aagctctccc   3540
ggctcacccc tccagacccg ctgcccatcc ctcttccttg ctccatgccc aggggctgac   3600
ttgtaaaggc caagtcatca agctttcttg ccctttggat gttggtcagt ggggagccgg   3660
agagctggag ctggggtcgg aggaggtagt aggtggaggt gttcttccct gattcccttg   3720
cgggatgcct cgggctggcc tcccctgagg gtcttagctc cgagagggga ccctcttttc   3780
cacacagcct tctccacctc tggattttgg taactgctcc ctcctcatcc cttcaggatt   3840
agtggcctca gtgggagtct ggcttttact agtcctggcg gacttgtggt ttctacataa   3900
tgtgctcgca cttttgcaaa aaatcttttt atagaaccct cctcagataa ttctgagtgn   3960
ntcatctatt tccctgactg gtacagtatc tcttctgaaa aagcagagtg cattcaagtc   4020
tgtaggaaaa cccttttctt agggaggtga ttttttttct ctctctgctt cttatttggc   4080
ctactttaca atttctaact aactagttat tggcatttac tgacagtaaa ttattgcagt   4140
caccaataaa tgatagtaca ttgtgaaaca aaatatttgc tcatattagc aaataggaca   4200
ttctttggct ttgaagtctt tcttttgtga agacttcaca cacggttgct tcagcacaca   4260
gttgctgctc aggttttatg tatagatgat aataatagaa agcacagttt actaacatgg   4320
taaaccaacg gagttcaagt caagtcagtt aataccctaa gaattagatt ttatttctta   4380
ttctgaaaac ttgctacaca gggacttatc taacccatag tgtgctctgt tgctgacttg   4440
attcaagttg cagcgtgttt tgcgctgact ctaaggtgcg gaaatcctca cacctggcaa   4500
aggagaattc aaactgaact ttttgaatat aaggcaaaaa cttcaagata agggaatatg   4560
attgatgatt ggtacgaaaa atgtcaaaat gtgttcccct aatacacgac aaaatagagt   4620
gacttctgga cataaatctg ccatttatta aaccattcac tacaacaaat aaataggtat   4680
aaaagtggaa ttggaatttt tatacttatt tgttgtagtg aatggtttaa taaaaataga   4740
aatcactggt aatttccacc ccaaactaaa ctatttccct tcttttaaaa aaatacacaa   4800
ccaagatttt aatgtaaaat attttgcttt aattgtattt tatgccttga ttaatgaaac   4860
atggaaatat tgattttcag ttttggtcac ctgaggaacc tatctttgtt tgcttttgga   4920
aaagcccatt ttctaaacag atacaatatt gccacaacaa tgtgcagaaa cctttttgat   4980
aataaaaaat tgttctttgc ctctaagtgg atatttgcaa ttattttctc tctcctaact   5040
agactgtaaa aagggctgct ttagatcctg tagcttactc cagttattag ttattaacaa   5100
acacccaagt ctcgaagata tttctaatta aaaaagaagg catattcaga gttcttttta   5160
aataaatgtt gtttactttt ataggcatct ttaaacttct ggattttggt atgccattta   5220
aaaatacttc cagatacaca tggaaattag taatactgca gccgtatcct tgcaaacaca   5280
tctgtcagtg tmaaaggttt caaggttttt cttaaaaaaa gaaaacaaaa aagcaarcac   5340
ctatastgcc caawtggggt ggttggtcac tggttagaag tccctcggga aagtgttgtg   5400
cctgtctcgt tgccgcctaa gaatagatag tgaccatttc cgtggatagg gccagcatt    5459

<210> 1319
<211> 1822
<212> DNA
<213> Homo sapiens

<400> 1319
ggctggcggc gggtccgggt ccgctgcctg gcgctgcggg cggcgggcca tggtggtttg     60
gattgagccg ggcccggccg gggcgccgag tcggaggggg tggcagtgag cggcggcaga    120
ggctacgggg ctcggtttgg ctgactgggg agtcggcagg cggcaggaac catgcgaggc    180
cagcggagcc tgctgctggg cccggcccgc ctctgcctcc gcctccttct gctgctgggt    240
tacaggcgcc gctgtccacc tctactccgg ggtctagtac agcgctggcg ctacggcaag    300
gtctgcctgc gctccctgct ctacaactcc tttgggggca gtgacaccgc tgttgatgct    360
gcctttragc ctgtctactg gctggtagac aacgtgatcc gctggtttgg agtggtgttc    420
gtggtcctgg tgatcgtgct gacaggctcc attgtagcta tcgcctacct gtgtgtcctg    480
cctctcatcc tccgaaccta ctcagtgcca cgactctgct ggcatttctt ctatagccac    540
tggaatctga tcctgattgt cttccactac taccaggcca tcaccactcc gcctgggtac    600
ccaccccagg gcaggaatga tatcgccacc gtctccatct gtaagaagtg catttacccc    660
aagccagccc gaacacacca ctgcagcatc tgcaacaggt gtgtgctgaa gatggatcac    720
cactgcccct ggctaaacaa ttgtgtgggc cactataacc atcggtactt cttctctttc    780
tgctttttca tgactctggg ctgtgtctac tgcagctatg gaagttggga ccttttccgg    840
gaggcttatg ctgccattga gaaaatgaaa cagctcgaca agaacaaact acaggcggtt    900
gccaaccaga cttatcacca gaccccacca cccaccttct cctttcgaga aaggatgact    960
cacaagagtc ttgtctacct ctggttcctg tgcagttctg tggcacttgc cctgggtgcc   1020
ctaactgtat ggcatgctgt tctcatcagt cgaggtgaga ctagcatcga aaggcacatc   1080
aacaagaagg agagacgtcg gctacaggcc aagggcagag tatttaggaa tccttacaac   1140
tacggctgct tggacaactg gaaggtattc ctgggtgtgg atacaggaag gcactggctt   1200
actcgggtgc tcttaccttc tagtcacttg ccccatggga atggaatgag ctgggagccc   1260
cctccctggg tgactgctca ctcagcctct gtgatggcag tgtgagctgg actgtgtcag   1320
ccacgactcg agcactcatt ctgctcccta tgttatttca agggcctcca agggcagctt   1380
ttctcagaat ccttgatcaa aaagagccag tgggcctgcc ttagggtacc atgcaggaca   1440
attcaaggac cagccttttt accactgcag aagaaagaca caatgtggag aaatcttagg   1500
actgacatcc ctttactcag gcaaacagaa gttccaaccc cagactaggg gtcaggcagc   1560
tagctaccta ccttgcccag tgctgacccg gacctcctcc aggatacagc actggagttg   1620
gccaccacct cttctacttg ctgtctgaaa aaacacctga ctagtacagc tgagatcttg   1680
gcttctcaac agggcaaaga taccaggcct gctgctgagg tcactgccac ttctcacatg   1740
ctgcttaagg gagcacaaat aaaggtattc gatttttaaa gawaaaaaaa aaaaaaaaaa   1800
tttggggggg ggggccccgt ta                                            1822

<210> 1320
<211> 3681
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (31)
<223> n equals a,t,g, or c

<400> 1320
gaacngncnc tcccctttag tttggacgcc ngcagccacc ggtccggaat tcccgggtcg     60
acccacgcgt ccgccctcct ctcctgtcct gcctccggcc ccgtgcctgc tcctgaggac    120
tctctggcca tctcccctta gaggtggacc cctgcgccca cggccatggg ggctgctccc    180
ctcatgccaa ctgtaccaag gtggcacctg ggcagcggac atgcacctgc caggatggct    240
acatgggcga cggggagctg tgccaggaaa ttaacagctg tctcatccac cacgggggct    300
gccacattca cgccgagtgc atctccactg gcccccagca ggtctcctgc agctgccgtg    360
agggttacag cggggatggc atccggacct gcgagctcct ggacccctgc tctaagaaca    420
atggaggatg cagcccatat gccacctgca aaagcacagg ggatggccag aggacatgta    480
cctgcgacac agcccacacc gtgggggacg gcctcacctg ccgtgcccga gtcggcctgg    540
agctcctgag ggataagcat gcctcattct tcagcctccg cctcctggaa tataaggagc    600
tcaagggcga tgggcctttc accatcttcg tgccgcacgc agatctaatg agcaacctgt    660
cgcaggatga gctggcccgg attcgtgcgc atcgccagct ggtgtttcgc taccacgtgg    720
ttggctgtcg gcggctgcgg agcgaggacc tgctggagca ggggtacgcc acggccctct    780
cagggcaccc actgcgcttc agcgagaggg agggcagcat atacctcaat gacttcgcgc    840
gcgtggtgag cagcgaccat gaggccgtga acggcatcct gcacttcatt gaccgtgtcc    900
tgctgccccc cgaggcgctg cactgggagc ctgatgatgc tcccatcccg aggagaaatg    960
tcaccgccgc cgcccagggc ttcggttaca agatcttcag cggcctcctg aaggtggccg   1020
gcctcctgcc cctgcttcga gaggcatccc ataggccctt cacaatgctg tggcccacag   1080
acgccgcctt tcgagctctg cctccggatc gccaggcctg gctgtaccat gaggaccacc   1140
gtgacaagct agcagccatt ctgcggggcc acatgattcg caatgtcgag gccttggcat   1200
ctgacctgcc caacctgggc ccacttcgaa ccatgcatgg gacccccatc tctttctcct   1260
gcagccgaac gcggcccggt gagctcatgg tgggtgagga tgatgctcgc attgtgcagc   1320
ggcacttgcc ctttgagggt ggcctggcct atggcatcga ccagctgctg gagccacctg   1380
gccttggtgc tcgctgtgac cactttgaga cccggcccct gcgactgaac acctgcagca   1440
tctgtgggct ggagccaccc tgtcctgagg ggtcacagga gcagggcagc cctgaggcct   1500
gctggcgctt ctacccgaag ttctggacgt cccctccgct gcactctttg ggattacgca   1560
gcgtctgggt ccaccccagc ctttggggta ggccccaagg cctgggcagg ggctgccacc   1620
gcaattgtgt caccaccacc tggaagccca gctgctgccc tggtcactat ggcagtgagt   1680
gccaagcttg ccctggcggc cccagcagcc cttgtagtga ccgtggcgtg tgcatggacg   1740
gcatgagtgg cagtgggcag tgtctgtgcc gttcaggttt tgctgggaca gcctgtgaac   1800
tctgtgctcc tggtgccttt gggccccatt gtcaagcctg ccgctgcact gtgcatggcc   1860
gctgtgatga gggccttggg ggctctggct cctgcttctg tgatgaaggc tggactgggc   1920
cacgctgtga ggtgcaactg gagctgcagc ctgtgtgtac cccaccctgt gcacccgagg   1980
ctgtgtgccg tgcaggcaac agctgtgagt gcagcctggg ctatgaaggg gatggccgyg   2040
tgtgtacagt ggcagacctg tgccaggacg ggcatggtgg ctgcagtgag cacgccaact   2100
gtagccaggt aggaacaatg gtcacttgta cctgcctgcc cgactacgag ggtgatggct   2160
ggagctgccg ggcccgcaac ccctgcacag atggccaccg cgggggctgc agcgagcacg   2220
ccaactgctt gagcaccggc ctgaacacac ggcgctgtga gtgccacgca ggctacgtag   2280
gcgatggact gcagtgtctg gaggagtcgg aaccacctgt ggaccgctgc ttgggccagc   2340
caccgccctg ccactcagat gccatgtgca ctgacctgca cttccaggag aaacgggctg   2400
gcgttttcca cctccaggcc accagcggcc cttatggtct gaacttttcg gaggctgagg   2460
cggcatgcga agcacaggga gccgtccttg cttcattccc tcagctctct gctgcccagc   2520
agctgggctt ccacctgtgc ctcatgggct ggctggccaa tggctccact gcccaccctg   2580
tggttttccc tgtggcggac tgtggcaatg gtcgggtggg catagtcagc ctgggtgccc   2640
gcaagaacct ctcagaacgc tgggatgcct actgcttccg tgtgcaagat gtggcctgcc   2700
gatgccgaaa tggcttcgtg ggtgacggga tcagcacgtg caatgggaag ctgctggatg   2760
tgctggctgc cactgccaac ttctccacct tctatgggat gctattgggc tatgccaatg   2820
ccacccagcg gggtctcgac ttcctggact tcctggatga tgagctcacg tataagacac   2880
tcttcgtccc tgtcaatgaa ggctttgtgg acaacatgac gctgagtggc ccagacttgg   2940
agctgcatgc ctccaacgcc accctcctaa gtgccaacgc cagccagggg aagttgcttc   3000
cggcccactc aggcctcagc ctcatcatca gtgacgcagg ccctgacaac agttcctggg   3060
cccctgtggc cccagggaca gttgtggtta gccgtatcat tgtgtgggac atcatggcct   3120
tcaatggcat catccatgct ctggccagcc ccctcctggc acccccacag ccccaggcag   3180
tgctggcgcc tgaagcccca cctgtggcgg caggcgtggg ggctgtgctt gccgctggag   3240
cactgcttgg cttggtggcc ggagctctct acctccgtgc ccgaggcaag cccatgggct   3300
ttggcttctc tgccttccag gcggaagatg atgctgatga cgacttctca ccgtggcaag   3360
aagggaccaa ccccaccctg gtctctgtcc ccaaccctgt ctttggcagc gacacctttt   3420
gtgaaccctt cgatgactca ctgctggagg aggacttccc tgacacccag aggatcctca   3480
cagtcaagtg acgaggctgg ggctgaaagc agaagcatgc acagggagga gaccactttt   3540
attgcttgtc tgggtggatg gggcaggagg ggctgagggc ctgtcccaga caataaaggt   3600
gccctcagcg gatgtgggcc atgtcaccaa raaaaaaaaa aaaaaactcg agggggggcc   3660
cgtaccsaat cccctatagt a                                             3681

<210> 1321
<211> 457
<212> DNA
<213> Homo sapiens

<400> 1321
cgggtcgacc cacgcgtccg gctgggcatc atcctcatcg gctacttcac cctagtgccc     60
gccatccagg agttctgtct ctttgctgtc gtggggctgg tgtctgactt cttccttcag    120
atgctgtttt tcaccactgt cctgtccatt gacattcgcc ggatggagct agcagacctg    180
aacaagcgac tgccccctga ggcctgcctg ccctcagcca agccagtggg gcagccaacg    240
cgctacgagc ggcagctggc tgtgaggccg tccacacccc acaccatcac gttgcagccg    300
tcttccttcc gaaacctgcg gctccccaag argctgcgtg ttgtctactt cctggcccgc    360
acccgcctgg cacagcgcct catcatggct ggcaccgttg tctggattgg catcctggta    420
tacacagacc cagcagggct gcgcaactac ctcgctg                             457

<210> 1322
<211> 4005
<212> DNA
<213> Homo sapiens

<400> 1322
tattatgaaa gattggcttg gtggttctga agtcaatcca ctatggacag cacttctgtt     60
tttattgtgt cactctgggt ccacttctgg aagccataat ttaggtgcac aacagaccag    120
tgcaagatca gcttctcttt cttcagctgc tacaacagga ctgactactc aacagcgcac    180
agcaattgag aatgcaactg ttgcgttctt tctacagtgc atttcatgcc atcctaataa    240
tcaaaagctg atggcacagg ttctttgtga actatttcag acatctcctc aaagagggaa    300
ccttccaaca tctgggaaca tttcagggtt tatacgaaga ttatttttac agttgatgct    360
ggaagatgag aaagtgacaa tgtttcttca gtctccatgt ccactgtaca aaggtagaat    420
taatgctact agccacgtca tccagcatcc aatgtatgga gcaggccaca aattccgtac    480
tcttcatttg ccagtctcaa caacattatc agatgttctt gacagagtgt cagatactcc    540
aagtatcaca gctaaattaa ttagtgaaca aaaagatgac aaagaaaaga aaaaccatga    600
agagaaagaa aaagttaaag cggaaaatgg atttcaagac aattacagtg ttgttgttgc    660
ctctgggctg aagtctcaat ctaaacgtgc tgtgtcagct acaccacctc gcccaccatc    720
caggaggggg aggacaatac ctgataaaat aggaagtact tcaggagcag aggctgccaa    780
caaaataatt actgtcccag tgtttcacct gtttcacaaa ctcttggcag gccagccatt    840
gccagctgaa atgacacttg cccagctttt aactctccta tatgaccgaa aacttcctca    900
gggttaccgc tcaatagatc tgactgttaa attgggatca agagttataa cagaccccag    960
tctatcaaaa acagattctt ataaaagact acaccctgaa aaagatcatg gagacttact   1020
tgctagctgt ccagaagatg aggctctcac tccaggtgat gaatgcatgg atgggatact   1080
ggatgaatct ttgcttgaaa cctgtccaat tcagtcacca ttacaagttt ttgcaggaat   1140
gggtggactg gctcttattg ctgaaagact acccatgcta tatccagaag taattcaaca   1200
ggtgagtgct ccagttgtaa catctaccac tcaggaaaag ccgaaggata gcgatcagtt   1260
tgaatgggtg accattgaac agtcagggga gttagtttat gaagcaccag aaactgttgc   1320
ggctgaacct ccacctatca agtcagcagt acagaccatg tctcccatac ctgcccattc   1380
tttggctgct tttggattat ttcttcgtct tccgggctat gcggaagtgc tactgaaaga   1440
gagaaaacat gcccagtgcc ttcttcgatt ggtattggga gtgacagatg atggagaagg   1500
aagtcatatt cttcaatctc catcagccaa tgtgcttcca acccttcctt tccacgtcct   1560
tcgtagcttg tttagcacta cacctttgac aactgatgat ggtgtacttc taaggcggat   1620
ggcattggaa attggagcct tacacctcat tcttgtctgt ctctctgctt tgagccacca   1680
ttccccacga gttccaaact ctagcgtgaa tcaaactgag ccacaggtgt caagctctca   1740
taaccctaca tcaacagaag aacaacagtt atattgggcc aaagggactg gctttggaac   1800
aggctctaca gcttctgggt gggatgtgga acaagcctta actaagcaaa ggctggaaga   1860
ggaacatgtt acctgccttc tgcaggttct tgccagttac ataaatcccg tcagtagtgc   1920
ggtaaatgga gaagctcagt catctcatga gactagaggg cagaacagta atgcccttcc   1980
ttctgtactt ctcgagcttc tcagtcagtc ctgcctcatc ccagccatgt catcttatct   2040
acsaamygwt tmagatctaa aagggaaaat gttaaaacag gagtaaaacc agatgcgtct   2100
gatcaagaac cagaaggact tactcttttg gtaccagaca tccaaaagac tgctgagata   2160
gtttatgcag ccaccaccag tttgcggcaa gcaaatcagg aaaaaaaact gggtgaatac   2220
tccaagaagg cggctatgaa acccaaacct ttgtcagtat taaagtcact tgaagaaaaa   2280
tatgtggctg ttatgaagaa attacagttt gatacgtttg aaatggtttc tgaagatgaa   2340
gatgggaaat tgggatttaa agtaaattac cactacatgt ctcaggtgaa aaatgctaat   2400
gatgcgaaca gtgctgccag agctcgccgc cttgcccagg aagctgtgac actttcaacc   2460
tcactgcctc tgtcttcatc ctctagtgtg tttgtacgct gtgatgagga gcgacttgat   2520
atcatgaagg wtctaataac tggtccagcg gacacccctt atgcaaatsg ctgctttgag   2580
tttgatgtgt attttcctca agattatccc agttcacccc ctcttgtgaa tctagagaca   2640
actggtggtc atagcgtgcg attcaatcca aacctttata atgatggcaa ggtttgttta   2700
agcatcttaa acacgtggca tggaagacca gaagagaagt ggaatcctca gacctcaagc   2760
tttttgcaag tgttggtgtc tgtccagtcc cttatattag tagctgagcc ttattttaat   2820
gaaccgggat atgaacggtc tagaggcact cccagtggca cacagagttc tcgagaatat   2880
gatggaaaca ttcgacaagc aacagttaag tgggcaatgc tagaacaaat cagaaaccct   2940
tcaccatgtt ttaaagaggt aatacacaaa catttttact tgaaaagagt tgagataatg   3000
gcccaatgtg aggagtggat tgcggatatc cagcagtaca gcagtgataa gcgggtaggc   3060
aggactatgt ctcaccatgc agcagctctc aagcgtcaca ctgctcagct ccgcgaagag   3120
ttgctgaaac ttccctgccc tgaaggcttg gatcctgaca ctgacgatgc cccagaggtg   3180
tgcagagcca caacaggtgc tgaggagact ctaatgcatg atcaggttaa acccagcagc   3240
agcaaagaac tccccagtga cttccagtta tgagctgcat tgatgtggac ttcatagaca   3300
caaaggcttc gaagcacaag ccaaatatgt caatatttgt atgtaagaaa ctaattatgt   3360
aataggtaat gaaactgaaa ctatactatg cccttaagga gatccagttt aattcaaggt   3420
gatcttttat ttacctgtac aggagtgtaa acttttttgt gcttttattt ttcaattgtg   3480
agaaccactg attggtatgt tcaacaaatt tgtgtataca aagaaatgga taaatcactg   3540
ctatataagg gaaactacct taggaaagaa tgtttactga atgtttattt tatttttttt   3600
tttttttact atagagtgag gggttgttaa caaagaatat atattggtca ttcttacaac   3660
tactatttaa agtcagcaac ttttcactga atttgataga ttttatgttt ggccatatct   3720
tcatgctcac atttgatttc tgaagacctc ctacatacac ttcaataaaa gttaaatgga   3780
catactccct cttttttgat ttactggtac atttttaaaa taataaatct gccataaaat   3840
gcattatatc tggagacttg cacttgtatg gatgaattta ttacattcaa catatttaat   3900
tttatgcctt ctaattctaa gatgcagaaa aaaataaatg aacatgattt tattctawra   3960
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ctcga                   4005

<210> 1323
<211> 765
<212> DNA
<213> Homo sapiens

<400> 1323
gggatcaggc ctccaggtgg gagccccasg agcagaggaa gaggtggaag agtcctcacc     60
actgcaagag ccaccaagcc aggcagcagg caccacccct ggtccagacc ctaaggccta    120
tcagcttcta tcagcccgca gtgcctgcct gctgggcctg ttggccgcca ccaacgcgct    180
gaccaatggc gtgctgcctg ccgtgcagag cttttcctgc ttaccctacg ggcgtctggc    240
ctaccacctg gctgtggtgc tgggcagtgc tgccaatccc ctggcctgct tcctggccat    300
gggtgtgctg tgcaggtcct tggcagggct gggcggcctc tctctgctgg gcgtgttctg    360
tgggggctac ctgatggcgc tggcagtcct gagcccctgc ccgcccctgg tgggcacctc    420
ggcgggggtg gtcctcgtgg tgctgtcgtg ggtgctgtgt cttggcgtgt tctcctacgt    480
gaaggtggca gccagctccc tgctgcatgg cgggggccgg ccggcattgc tggcagccgg    540
cgtggccatc caggtgggct ctctgctcgg cgctgttgct atgttccccc cgaccagcat    600
ctatcacgtg ttccacagca gaaaggactg tgcagacccc tgtgactyct gagcctkggc    660
aggtggggac cccgctyccc aacacctgty tttcctcaat gctgccggca tgcctgagtg    720
cctgcagccc aggaggcccg acaccggtac actcgtggac accta                    765

<210> 1324
<211> 1892
<212> DNA
<213> Homo sapiens

<400> 1324
ccctgcctgc cggcggtccc gctggctaga wgaagtcttc acttcccagg agagccaaag     60
cgtgtctggc cctaggtggg aaaagaactg gctgtgacct ttgccctgac ctggaagggc    120
ccagccttgg gctgaatggc agcacccacg cccgcccgtc cggtgctgac ccacctgctg    180
gtggctctct tcggcatggg ctcctgggct gcggtcaatg ggatctgggt ggagctacct    240
gtggtggtca aagagcttcc agagggttgg agcctcccct cttacgtctc tgtgcttgtg    300
gctctgggga acctgggtct gctggtggtg accctctgga ggaggctggc cccaggaaag    360
gacgagcagg tccccatccg ggtggtgcag gtgctgggca tggtgggcac agccctgctg    420
gcctctctgt ggcaccatgt ggccccagtg gcaggacagt tgcattctgt ggccttctta    480
gcactggcct ttgtgctggc actggcatgc tgtgcctcga atgtcacttt cctgcccttc    540
ttgagccacc tgccacctcg cttcttacgg tcattcttcc tgggtcaagg cctgagtgcc    600
ctgctgccct gcgtgctggc cctagtgcag ggtgtgggcc gcctcgagtg cccgccagcc    660
cccatcaacg gcacccctgg ccccccgctc gacttccttg agcgttttcc cgccagcacc    720
ttcttctggg cactgactgc ccttctggtc gcttcagctg ctgccttcca rggtcttctg    780
ctgctgttgc cgccaccacc atctgtaccc acaggggagt taggatcagg cctccaggtg    840
ggagccccag gagcagagga agaggtggaa gagtcctcac cactgcaaga gccaccaagc    900
caggcagcag gcaccacccc tggtccagac cctaaggcct atcagcttct atcagcccgc    960
agtgcctgcc tgctgggcct gttggccgcc accaacgcgc tgaccaatgg cgtgctgcct   1020
gccgtgcaga gcttttcctg cttaccctac gggcgtctgg cctaccacct ggctgtggtg   1080
ctgggcagtg ctgccaatcc cctggcctgc ttcctggcca tgggtgtgct gtgcaggtac   1140
acaaggaccc ccagcccctg tgcgggtgga actcagggct gggagccagg tcctggcgca   1200
gtcagccctg acattctgct cgctcactgc aggtccttgg cagggctggg cggcctctct   1260
ctgctgggcg tgttctgtgg gggctacctg atggcgctgg cagtcctgag cccctgcccg   1320
cccctggtgg gcacctcggc gggggtggtc ctcgtggtgc tgtcgtgggt gctgtgtctt   1380
ggcgtgttct cctacgtgaa ggtggcagcc agctccctgc tgcatggcgg gggccggccg   1440
gcattgctgg cagccggcgt ggccatccag gtgggctctc tgctcggcgc tgttgctatg   1500
ttccccccga ccagcatcta tcacgtgttc cacagcagaa aggactgtgc agacccctgt   1560
gactcctgag cctgggcagg tggggacccc gctccccaac acctgtcttt ccctcaatgc   1620
tgccaccatg cctgagtgcc tgcagcccag gaggcccgca caccggtaca ctcgtggaca   1680
cctacacact ccataggaga tcctggcttt ccagggtggg caagggcaag gagcaggctt   1740
ggagccaggg accagtgggg gctgtagggt aagcccctga gcctgggacc tacatgtggt   1800
ttgcgtaata aaacatttgt atttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1860
aaaaaaaaaa aaaaaaaaaa aaaagggcgg cc                                 1892

<210> 1325
<211> 1186
<212> DNA
<213> Homo sapiens

<400> 1325
gcggacgcgt gggcagcccg ggcggctgcc cttgggtgct cccttccctg cccgacaccc     60
agaccgacct tgaccgccca cctggcagga gcaggacagg acggccggac gcggccatgg    120
ccgagctccc ggggcccttt ctctgcgggg ccctgctagg cttcctgtgc ctgagtgggc    180
tggccgtgga ggtgaaggta cccacagagc cgctgagcac gcccctgggg aagacagccg    240
agctgacctg cacctacagc acgtcggtgg gagacagctt cgccctggag tggagctttg    300
tgcagcctgg gaaacccatc tctgagtccc atccaatcct gtacttcacc aatggccatc    360
tgtatccaac tggttctaag tcaaagcggg tcagcctgct tcagaacccc cccacagtgg    420
gggtggccac actgaaactg actgacgtcc acccctcaga tactggaacc tacctctgcc    480
aagtcaacaa cccaccagat ttctacacca atgggttggg gctaatcaac cttactgtgc    540
tggttccccc cagtaatccc ttatgcagtc agagtggaca aacctctgtg ggaggctcta    600
ctgcactgag atgcagctct tccgaggggg ctcctaagcc agtgtacaac tgggtgcgtc    660
ttggaacttt tcctacacct tctcctggca gcatggttca agatgaggtg tctggccagc    720
tcattctcac caacctctcc ctgacctcct cgggcaccta ccgctgtgtg gccaccaacc    780
agatgggcag tgcatcctgt gagctgaccc tctctgtgac cgaaccctcc caaggccgag    840
tggccggagc tctgattggg gtgctcctgg gcgtgctgtt gctgtcagtt gctgcgttct    900
gcctggtcag gttccagaaa gagaggggga agaagcccaa ggagacatat gggggtagtg    960
accttcggga ggatgccatc gctcctggga tctctgagca cacttgtatg agggctgatt   1020
ctagcaaggg gttcctggaa agaccctcgt ctgccagcac cgtgacgacc accaagtcca   1080
agctccctat ggtcgtgtga cttctcccga tccctgaggg cggtgagggg gaatatcaat   1140
aattaaagtc tgtgggtacc aaaaaaaaaa aaaaaaaagt cgacgc                  1186

<210> 1326
<211> 1467
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1434)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1440)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1460)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1464)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1467)
<223> n equals a,t,g, or c

<400> 1326
gctgagctat aagacaacag gactgaacag ggagccaact gtttctttga acagtaaatc     60
aggaacacca atggaccaaa atgaacacag tcactgggga ccacatgcaa agggccaatg    120
tgccagcaga tctgagctga gaatcatcct ggtgggcaaa acaggaactg gcaaaagtgc    180
tgcagggaac agcatcctca ggaagcaagc atttgaatcg aagctgggtt cccagacctt    240
gactaagact tgcagcaaaa gtcagggaag ctggggaaat agagagattg tcattattga    300
cacaccagat atgttttctt ggaaggacca ctgtgaagct ctgtacaaag aggtgcagag    360
gtgctacttg ctgtctgcac caggacccca tgtgctgctc ctggtgactc agctgggccg    420
ctatacctca caggaccagc aggctgcaca garggtgaag gagatctttg gaaaggatgc    480
catgggacac acaattgtcc tctttaccca caaggaagac ctcaatggtg gctccctgat    540
ggattacatg cacgactcag ataacaaagc cctaagcaag ctggtggcag matgtggtgg    600
gcgaatctgt gcctttaata accgtgctka agggagcaat caggatgacc aagtgaagga    660
actaatggac tgtattgagg atctgttgat ggagaaaaat ggtgatcact ataccaatgg    720
gttgtacagc ctaatacaga ggtctaaatg tggacctgtg ggatcagatg aaagagtaaa    780
ggaattcaaa cagagcctta taaagtacat ggaaactcaa agaagttaca cagccttggc    840
traagcaaac tgcctaaaag gagccttaat caaaacacaa ctgtgtgttt tattttgtat    900
tcagttgttt ctcagattga taattctgtg gctttgcata ctgcacagca tgtgcaattt    960
gttttgttgc ttactcttta gtatgtgcaa tttattctgc agtttgctgt ttattatacc   1020
caaaaagtta atgatatttt tgagaacagt tattagacta gaacgcaaga ctcctaggtt   1080
atagttacag atcccagtta ttatttactc actatcattt agtgggtgaa tcacagtaat   1140
ttccctgtaa aatgtggtac ctgaagtcat atttgagatt ctatgaaatg tttaaatctk   1200
aacatcactc caattattaa tgaaccaaat catacgataa gttactgttt gcattgaaat   1260
ataatatcaa agccttttga aatctgtaaa cataaaattc ctctcatttt caaatatcta   1320
aagccagttt tatgttccta aaatctcatt ttcttctttc tagtactact atttctactg   1380
aatataatga aaatggcaat aaaataatat tacataaact gtaaaaaaaa amanaaaaan   1440
aaaaaaaaaa ggggggcccn tttnaan                                       1467

<210> 1327
<211> 638
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (386)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (566)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (610)
<223> n equals a,t,g, or c

<400> 1327
tacgaccgac gagccggtgt cgtggtcgcg gtacctgttc caacacggct cgcgggcccg     60
tgccggctcc ggtccccggc gcggctgtcc gagcccctgc ggcgggcgga cgatggtgtg    120
gcggaacacg caggacgcgg cggcmgcggc ggcgggcatg aaggaggatg gaagggcagg    180
acgaggtgtc ggcgcgggag cagcacttcc acagccaagt gcgggagtcc acgatatgtt    240
tccttctttt tgccattctc tacgttgttt cctacttcat catcacaaga tacaagagaa    300
aatcagatga acaagaagat gaagatgcca tcgtcaacag gatttcgttg tttttgagca    360
cgttcactct cgcagtgtca gctggngctg ttttgctttt acccttctca atcatcagca    420
atgaaatcct gctttctttt cctcagaact actatattca gtggctaaat ggctccctga    480
ttcatggttt gtggaatctt gcttcctttt ttccaacctt tggttatttg tattgatgcc    540
ctttgccttt ttctttctgg aatcanaagg ctttgctggc ctgaaaaagg gaatccgacc    600
cgcattttan agactttggc atgcttcttc ttcttgcg                            638

<210> 1328
<211> 1052
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (19)
<223> n equals a,t,g, or c

<400> 1328
aaacncntca ctaaagggnt caaaagctgg agctccaccg cggtggcagg ccgctctaga     60
actagtggat cccccgggct gcaggaattc ggcacgaggg cttaggaccc ccagctccga    120
cgtaagtccc tctcgcgcgc cacctccatc cgctgcccct ctgccggctt aggaccccca    180
gctccgacat gtcgccctct ggtcgcctgt gtcttctcac catcgttggc ctgattctcc    240
ccaccagagg acagacgttg aaagatacca cgtccagttc ttcagcagac tcaactatca    300
tggacattca ggtcccgaca cgagccccag atgcagtcta cacagaactc cagcccacct    360
ctccaacccc aacctggcct gctgatgaaa caccacaacc ccagacccag acccagcaac    420
tggaaggaac ggatgggcct ctagtgacag atccagagac acacaagagc accaaagcag    480
ctcatcccac tgatgacacc acgacgctct ctgagagacc atccccaagc acagacgtcc    540
agacagaccc ccagaccctc aagccatctg gttttcatga ggatgacccc ttcttctatg    600
atgaacacac cctccggaaa cgggggctgt tggtcgcagc tgtgctgttc atcacaggca    660
tcatcatcct caccagtggc aagtgcaggc agctgtcccg gttatgccgg aatcattgca    720
ggtgagtcca tcagaaacag gagctgacaa ccygctgggc acccgaagac caagccccct    780
gccagctcac cgtgcccagc ctcctgcatc ccctcgaaga gcctggccag agagggaaga    840
cacagatgat gaagctggag ccagggctgc cggtccgagt ctcctacctc ccccaaccct    900
gcccgcccct gaaggctacc tggcgccttg ggggctgtcc ctcaagttat ctcctctgyt    960
aagacaaaaa gtaaagcact gtggtctttg maaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1020
aaaaaaaaaa aaaaaaaaaa aaaaaactcg ag                                 1052

<210> 1329
<211> 2197
<212> DNA
<213> Homo sapiens

<400> 1329
agcccgggtc cacagccgca ctcackcgyc cgctctccgc caccgccacc actgcggcca     60
ccgccaatga aacgcctccc gctcctagtg gttttttcca ctttgttgaa ttgttcctat    120
actcaaaatt gcaccaagac accttgtctc ccaaatgcaa aatgtgaaat acgcaatgga    180
attgaagcct gctattgcaa catgggattt tcaggaaatg gtgtcacaat ttgtgaagat    240
gataatgaat gtggaaattt aactcagtcc tgtggcgaaa atgctaattg cactaacaca    300
gaaggaagtt attattgtat gtgtgtacct ggcttcagat ccagcagtaa ccaagacagg    360
tttatcacta atgatggaac cgtctgtata gaaaatgtga atgcaaactg ccatttagat    420
aatgtctgta tagctgcaaa tattaataaa actttaacaa aaatcagatc cataaaagaa    480
cctgtggctt tgctacaaga agtctataga aattctgtga cagatctttc accaacagat    540
ataattacat atatagaaat attagctgaa tcatcttcat tactaggtta caagaacaac    600
actatctcag ccaaggacac cctttctaac tcaactctta ctgaatttgt aaaaaccgtg    660
aataattttg ttcaaaggga tacatttgta gtttgggaca agttatctgt gaatcatagg    720
agaacacatc ttacaaaact catgcacact gttgaacaag ctactttaag gatatcccag    780
agcttccaaa agaccacaga gtttgataca aattcaacgg atatagctct caaagttttc    840
ttttttgatt catataacat gaaacatatt catcctcata tgaatatgga tggagactac    900
ataaatatat ttccaaagag aaaagctgca tatgattcaa atggcaatgt tgcagttgca    960
tttttatatt ataagagtat tggtcctttg ctttcatcat ctgacaactt cttattgaaa   1020
cctcaaaatt atgataattc tgaagaggag gaaagagtca tatcttcagt aatttcagtc   1080
tcaatgagct caaacccacc cacattatat gaacttgaaa aaataacatt tacattaagt   1140
catcgaaagg tcacagatag gtataggagt ctatgtgcat tttggaatta ctcacctgat   1200
accatgaatg gcagctggtc ttcagagggc tgtgagctga catactcaaa tgagacccac   1260
acctcatgcc gctgtaatca cctgacacat tttgcaattt tgatgtcctc tggtccttcc   1320
attggtatta aagattataa tattcttaca aggatcactc aactaggaat aattatttca   1380
ctgatttgtc ttgccatatg catttttacc ttctggttct tcagtgaaat tcaaagcacc   1440
aggacaacaa ttcacaaaaa tctttgctgt agcctatttc ttgctgaact tgtttttctt   1500
gttgggatca atacaaatac taataagctc ttctgttcaa tcattgccgg actgctacac   1560
tacttctttt tagctgcttt tgcatggatg tgcattgaag gcatacatct ctatctcatt   1620
gttgtgggtg tcatctacaa caagggattt ttgcacaaga atttttatat ctttggctat   1680
ctaagcccag ccgtggtagt tggattttcg gcagcactag gatacagata ttatggcaca   1740
accaaagtat gttggcttag caccgaaaac aactttattt ggagttttat aggaccagca   1800
tgcctaatca ttcttgttaa tctcttggct tttggagtca tcatatacaa agtttttcgt   1860
cacactgcag ggttgaaacc agaagttagt tgctttgaga acataaggtc ttgtgcaaga   1920
ggagccctcg ctcttctgtt ccttctcggc accacctgga tctttggggt tctccatgtt   1980
gtgcacgcat cagtggttac agcttacctc ttcacagtca gcaatgcttt ccaggggatg   2040
ttcatttttt tattcctgtg tgttttatct agaaagattc aagaagaata ttacagattg   2100
ttcaaaaatg tcccctgttg ttttggatgt ttaagctgtt gaaatgaagt ctgccaaatc   2160
ttgctctaac aaataaaatg ttatctaaat gaaaaaa                            2197

<210> 1330
<211> 2333
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2018)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2044)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2292)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2306)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2331)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2332)
<223> n equals a,t,g, or c

<400> 1330
cacgcgtccg cattttcgta tccctgctga tttcaaacct tcccatggtt tagaagcata     60
acctgtaatg taatgcaagt cccctaactc cctggttgct aacattaact tccttaagta    120
ataatcaatg aaagaaattc tatgcatggt tttgaaataa tgtccttgaa agaggaatca    180
ccattaggaa aggtgagtca gggtcctttg tttaatgtga ctagtggctc atcatcacca    240
gtgacctggt tgggcctact ctccttccag aacctgcatt gcttcccaga cctccccact    300
gagatgcctc taagagccaa aggagtcaac acttgagcct agggtgggct acaacaaaag    360
attctaattt accttgcttc atctaggtcc aggccccaag tagcttgctg aaggaactta    420
aaaagtagct gttatttatt gtattrtata agctaaaaac atttattttt gttgaatcga    480
aacaattcca tgtagcaatc ttttttctgt tcacggtgtt tgtgatagaa ccttaaattc    540
cgcaagcatc agttttttga aaaaatggga attgaccgga tagttacagg caaagattat    600
aaatwgctac aacatcattt aacttttata aacatgcctt ctctctattg aagacatctg    660
atatttttgc tggaaagttg gatctatcct cagtaactct gccatggaat tcctgkttcc    720
tggttccaga aaaagaaaag attacatttc tgatcataaa gaatgtcttg catatgggga    780
aatttttcaa aatgaagggg ggtattattt atgtgggcat gggaaaactt ttgccatggc    840
tgtttgtctt agtgggcatc ttttgatgam attggatcag atatatgtag atgctgatat    900
atgggacaca tgtttaggtt ttggtgcagt tgcacaaaac tgtgttagtt tatatgttac    960
tgtgttgcct ttatttattc tctccaaagt gtctctttat atttgtttta caatctgtga   1020
aagagtatac cataatacag aagtattttc atagtcttta cctctggatt gtcctgtcag   1080
tatagccacg ttgatgagat tacaccagtg cctttgatca tctttaagta tttgagccct   1140
gataaatatt ttggtaacat aatccaaatt agagacttag agctctggtt agcaatcatg   1200
tttaaagaga agcttcttaa agctctgtat gctgggagat tcatgattat taccaacgtt   1260
ttgatttcat gaaggtgttc tcaaatttaa agcacatttt cagtaagaac aaaaatattt   1320
aatgttttta tcttagactt aacttgatac atttgcatat tactatggaa gttattcacc   1380
ttgtccctgt ttttctttaa gatattttaa aatcatagtt atactacagt ccttttttaa   1440
atgtatcctg atacattgta aaatatttta atttcattgt ggaaaataat gttggataag   1500
gagatatttt tcactgttaa cttttagccc atgcattttc ataatttatt tttttcactt   1560
gctgctttat atgacatatg tgacatttga ttatttaaca cttgatgtga tctgcataaa   1620
cccaagttgc acaaccctcc tgctgaagat aaaattgagg ttaaagataa agatttattt   1680
tcatatttgt acagtgatcg gcttcagtga tggtttttgt gggcatttat tgtgtgtgtg   1740
taagaaattt catatgtata tattaagtag gcctctgagt attgaataat tgttttatga   1800
ttttgattta tatggtttac attttcattg tgtgggccat atttcgttta tactgtttat   1860
ttctcttcaa accttaataa ttataccata aagtgtaatt tttatagcaa tgcaaatgtc   1920
taaggaacta caaatatttt ctacgttgta aattcaataa agcttgcttc ctttggcaaa   1980
aaaaaaaaaa aaaaaaaaaa ctcgaggggg ggcccggnac ccaattcgcc ctatagtgag   2040
tcgnattaca attcactggc cgtcgtttta caacgtcgtg actgggaaaa ccctggcgtt   2100
acccaactta atcgccttgc agcacatccc cctttcgcca gctggcgtaa tagcgaagag   2160
gcccgcaccg atcgcccttc ccaacagttg cgcagcctga atggcgaatg gcaaattgta   2220
agcgttaata ttttgttaaa attcgcgtta aatttttgct aaatcagctc attttttaaa   2280
accccccccc cnaaaaaaaa tttttnaaag gggggggggc cccccccccc nng          2333

<210> 1331
<211> 2317
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2315)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2316)
<223> n equals a,t,g, or c

<400> 1331
ttcctcgtag cgagcctagt ggcgggtgtt tgcattgaaa cgtgagcgcg acccgacctt     60
aaagagtggg gagcaaaggg aggacagagc cctttaaaac gaggcgggtg gtgcctgccc    120
ctttaagggc ggggcgtccg gacgactgta tctgagcccc agactgcccc gagtttctgt    180
cgcaggctgc gaggaaaggc ccctaggctg ggtctgggtg cttggcggcg gcggcttcct    240
ccccgctcgt cctccccggg cccagaggca cctcggcttc agtcatgctg agcagagtat    300
ggaagcacct gactacgaag tgctatccgt gcgagaacag ctattccacg agaggatccg    360
cgagtgtatt atatcaacac ttctgtttgc aacactgtac atcctctgcc acatcttcct    420
gacccgcttc aagaagcctg ctgagttcac cacaggctcg agctgtgcac ctttaccctg    480
gcaattgccc tgggtgctgt cctgctcctg cccttctcca tcatcagcaa tgaggtgctg    540
ctctccctgc ctcggaacta ctacatccag tggctcaacg gctccctcat ccatggcctc    600
tggaaccttg tttttctctt ctccaacctg tccctcatct tcctcatgcc ctttgcatat    660
ttcttcactg agtctgaggg ctttgctggc tccagaaagg gtgtcctggg ccgggtctat    720
gagacagtgg tgatgttgat gctcctcact ctgctggtgc taggtatggt gtgggtggca    780
tcagccattg tggacaagaa caaggccaac agagagtcac tctatgactt ttgggagtac    840
tatctcccct acctctactc atgcatctcc ttccttgggg ttctgctgct cctggtgtgt    900
actccactgg gtctcgcccg catgttctcc gtcactggga agctgctagt caagccccgg    960
ctgctggaag acctggagga gcagctgtac tgctcagcct ttgaggaggc agccctgacc   1020
cgcaggatct gtaatcctac ttcctgctgg ctgcctttag acatggagct gctacacaga   1080
caggtcctgg ctctgcagac acagagggtc ctgctggaga agaggcggaa ggcttcagcc   1140
tggcaacgga acctgggcta ccccctggct atgctgtgct tgctggtgct gacgggcctg   1200
tctgtgctca ttgtggccat ccacatcctg gagctgctca tcgatgaggc tgccatgccc   1260
cgaggcatgc agggtacctc cttaggccag gtctccttct ccaagctggg ctcctttggt   1320
gccgtcattc aggttgtact catcttttac ctaatggtgt cctcagttgt gggcttctat   1380
agctctccac tcttccggag cctgcggccc agatggcacg acactgccat gacgcagata   1440
attgggaact gtgtctgtct cctggtccta agctcagcac ttcctgtctt ctctcgaacc   1500
ctggggctca ctcgctttga cctgctgggt gactttggac gcttcaactg gctgggcaat   1560
ttctacattg tgttcctcta caacgcagcc tttgcaggcc tcaccacact ctgtctggtg   1620
aagaccttca ctgcagctgt gcgggcagag ctgatccggg cctttgggct ggacagactg   1680
ccgctgcccg tctccggttt cccccaggca tctaggaaga cccagcacca gtgacctcca   1740
gctgggggtg ggaaggaaaa aactggacac tgccatctgc tgcctaggcc tggagggaag   1800
cccaaggcta cttggacctc aggacctgga atctgagagg gtgggtggca gaggggagca   1860
gagccatctg cactattgca taatctgagc cagagtttgg gaccaggacc tcctgctttt   1920
ccatacttaa ctgtggcctc agcatggggt agggctgggt gactgggtct agcccctgat   1980
cccaaatctg tttacacatc aatctgcctc actgctgttc tgggccatcc ccatagccat   2040
gtttacatga tttgatgtgc aatagggtgg ggtaggggca gggaaaggac tgggccaggg   2100
caggctcggg agatagattg tctcccttgc ctctggccca gcagagccta agcactgtgc   2160
tatcctggag gggctttgga ccacctgaaa gaccaagggg atagggagga ggaggcttca   2220
gccatcagca ataaagttga tcccagggtt tgctttgttt ttttaaaaaa aaaaaaaaaa   2280
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaanna                            2317

<210> 1332
<211> 2167
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (13)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (52)
<223> n equals a,t,g, or c

<400> 1332
ancgagtcag tanngagaag cgaaagcgcc caatacgcaa accgcctctc cncgcgcgtt     60
ggccgattca ttaatcagct ggccgacagg tttcccgayt graaaggggc agtgagcgca    120
acgcaattaa tgtgagttag ctcacttcat taggcacccc aggctttaca ctttatgctt    180
ccggctcgta tgttgtgtgg aattgtgagc ggataacaat ttcacacagg aaacagctat    240
gaccatgatt acgccaagct cgaaattaac cctcactaaa gggaacaaaa gctggagctc    300
caccgcggtg gcggccgctc tagaactagt ggatcccccg ggctgcagga attcggcacg    360
agaagatgcg accggcagac ggcattcgct gggaacgacg gatagactgg gggctgcggc    420
ctagaggtcc gggcttggag ttcgcctcag acgcggtgga gccgccggag tctgagaagg    480
tcttcaggca ccatggagga caaacgcaac atccagatca tcgagtggga acacctggac    540
aagaagaagt tctacgtgtt tggtgtggca atgacaatga tgatccgtgt cagtgtctac    600
ccattcaccc tcatccgcac ccggttgcaa gttcagaagg ggaagagcct ctaccatggg    660
accttcgatg ccttcatcaa gatcctgcga gcagatggta tcactggcct ctaccgaggg    720
ttcctggtca ataccttcac cctcatctct ggccagtgtt atgtcaccac ttatgagctc    780
acccggaagt ttgtagctga ctacagccag agtaacacag tcaaatcact ggtggctggt    840
ggctcagcct cccttgtggc ccagagcatc acagtgccca ttgatgtagt ctcccagcac    900
ctgatgatgc aacgcamggg tgagaaaatg ggccgctttc aggtgcgggg gaacccagag    960
ggacaagggg tagttgcctt tggccaaacc aaggacatca tcaggcagat cctgcaggct   1020
gatggacttc gcggcttcta tcgaggctat gtggcttcac tgcttaccta tatcccaaac   1080
agtgctgtct ggtggccctt ctatcacttc tatgcagagc agctctccta cctgtgtcct   1140
aaggagtgcc ctcacattgt ctttcaagct gtctcggggc ccctggctgc agccactgcc   1200
tccatcctca ccaatcccat ggatgtcata cgaacccgtg tgcaggttga gggcaagaac   1260
tccatcatcc tgaccttcag acagctgatg gcagaagaag ggccttgggg cctcatgaag   1320
ggcctctcgg ccagaatcat ctcagccaca ccttccacca ttgtcattgt ggtgggctat   1380
gagagcctca agarastcgc tccagtttct atccaggaat gttcacatcc aaagggttgg   1440
acccacggat cattctgaat cttcctgccc ctcctcactg cttaaccctg agaaccacaa   1500
atataatgga agcagttccc cccaccctca ccccatctct ttaagctcat cctagcaaga   1560
cctctagaga ccctagagac tcgactttag tccttccccg ccatggcaca gtggggaagg   1620
tgtcaatggg gagtgtcacg gacaggaggt aggatcctgc cgctcgcgtc ttagtgtttc   1680
tccctcaaga ctttccttct gttttgttgt cttgtgcagt attttacagc ccctcttgtg   1740
tttttcttta tttctcgtac acacacgcag ttttaagggt gatgtgtgta taattaaaag   1800
gacccttggc ccatactttc ctaattcttt agggactggg attgggtttg actgaaatat   1860
gttttggtgg ggatgggacg gtggacttcc attctcccta aactggagtt ttggtcggta   1920
atcaaaacta aaagaaacct ctgggagact ggaaacctga ttggagcact gaggaacaag   1980
ggaatgaaaa ggcagactct ctgaacgttt gatgaaatgg actcttgtga aaattaacag   2040
tgaatattca ctgttgcact gtacgaagtc tctgaaatgt aattaaaagt ttttattgag   2100
cccccgaaaa aaaaaaaaaa aaaaaaaaaa aaaaactcga gggggggccc gtacccaatc   2160
gccctat                                                             2167

<210> 1333
<211> 589
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (535)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (536)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (581)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (588)
<223> n equals a,t,g, or c

<400> 1333
tgggctggaa cgcgccggaa tctgaggtgt gagtagagcc tgggggagag tggatccagg     60
tgaagggggc agaggactgg gagttttcrt cctcttgaat aagaactcga caacagagtg    120
ggaactttct gtcttgtgat ccattgcctg gtgagtcaca gctcacacca tggatttaac    180
ctgagagctt caacttctgc tttggccctg gagttcccat gccctggtgt cttctaccag    240
ttcttagtgt gttgcactgg agcacagagg acactcgatc gtgcggcgcg cagggcgggg    300
ggccgccgct gcctccccgc gggatggctg gcactgtgct cggagtcggt gcgggcgtgt    360
tcatcttagc cctgctctgg gtggcartgc tgctgctgtg tgtgctgytg tccaragsct    420
tccggggcgg cgargttctc tgttcatttt ttattcttcg gtgctgtgat catcacatca    480
ttctgttgct tttcccggga gtggtgattt ccagccccag aagtggaagt taagnngtgg    540
atgatttttc aatggccgta agtcctgtgg tttcttagtg ncaattcnt                589

<210> 1334
<211> 2541
<212> DNA
<213> Homo sapiens

<400> 1334
gggagtgaag gcctggttac ctctccagtg aagattagcc ccatagagct tactctatgg     60
ggaagaactt ttctgactcc ttcctgtcta gggagtgcgt gatcagaatg gtgtctggac    120
ggttctactt gtcctgcctg ctgctggggt ccctgggctc tatgtgcatc ctcttcacta    180
tctactggat gcagtactgg cgtggtggct ttgcctggaa tggcagcatc tacatgttca    240
actggcaccc agtgcttatg gttgctggca tggtggtatt ctatggaggt gcgtcactgg    300
tgtaccgcct gccccagtcg tgggtggggc ccaaactgcc ctggaaactc ctccatgcag    360
cgctgcacct gatggccttc gtcctcactg ttgtggggct ggttgctgtc tttacgtttc    420
acaaccatgg aaggactgcc aacctctact cccttcacag ctggctgggc atcaccactg    480
tcttcctctt cgcctgccag tggttcctgg gctttgctgt cttcctcctg ccctgggcgt    540
ccatgtggct gcgcagctcc taaaacctat ccacgtcttt tttggagccg ccatcctctc    600
tctgtccatc gcatccgtca tttcgggcat taatgagaag cttttcttca gtttgaaaaa    660
caccaccagg ccataccaca gcctgcccag tgaggcggtc tttgccaaca gcaccgggat    720
gctggtggtg gcctttgggc tgctggtgct ctacatcctt ctggcttcat cttggaagcg    780
cccagagccg gggatcctga ccgacagaca gcccctgctg catgatgggg agtgaagcag    840
caggaagggg ctcccaagag ctcctggtgg tgcagcctgt gctcccctca gaagctctgc    900
tcttcccagg gctcccggct ggtttcagca ggcgactttc ttccaatgct gggcccagac    960
ttcttgcctg ggtgctggcc tgccctctcc ggccgcttgc tgcctgtctg ctttccttgg   1020
tggctttgcc tgggtgctgg gcctgccctc tccggccgct tgctgcctgt ctgctttcct   1080
tggtggcttt gcctgggtgc tgggcctgcc ttctctggct gcttgctgcc tgtctgcttt   1140
ccttggtggc tttggcttct gcactccttg gcgtcagcct ctcaggtcct ccattcacac   1200
gaggtcctcc tcgctctggc cgctcttgct gctcctgtct gaagaaatca gactgatttc   1260
ctcttaagac tcctagggat gtggtgaaga gctgggactc aagtgcagtc cacggtgtga   1320
aacatgaggg aggtgaggtg tccgtccact tcccccataa aggtgtgcat ttcagttagg   1380
ctgccccgcc acagagcagg cttcatctgc tctgccatcc agccccatct ggatgtgagg   1440
tggggtggag acatcatggg gtgattgcag aaagggggag tggcggccca cgcagcttct   1500
gctgaggagc tgaccgctct gagctgttct gtttcgtatt gctgctctgt gtctgcatgt   1560
attgtgaccg tgcggctcca cctcttccag ctgctgctac agctgaggcc tggatcccgg   1620
cctttccctg tgacttacgt gtctgtcacc ggcaggcagc cctacaaatc ctggtgacct   1680
gctctcccaa gaacagagcc tgtccccaga tgtcccagta gcgatgagta acagaggtgg   1740
ctgtggactt cctctacttc tccttgctgg atcagggcct tcctgcctcc cgctgggcag   1800
gtctggcctt gctctcttgg cagggcccca gcccctctga ccactctgca gctcaccatg   1860
cagctgatgc caaagttgtg gtgtccagtg tgcagcagcc ctgggagcca ctgccacctt   1920
cagaggggtt ccttgctgag acccacattg cttcacctgg ccccaccatg gctgcttgcc   1980
tggcccaacc tagcgttctg tgccatgcta gagcttgagc tgttgctctt cttcagggga   2040
ggaaataggg tggagagcgg gaagggtctt gctcctaagt gttgctgctg tggctttttt   2100
gccttctcca aagacgcact gccaggtccc aagcttcaga ctgctgtgct tagtaagcaa   2160
gtgagaagcc tggggtttgg agcccaccta ctctctggca gcatcagcat cctactcctg   2220
gcaacatcag gccaacgtcc accccagcct cacattgcca gatgttggca gaagggctaa   2280
tattgaccgt cttgactggc tggagccttc aaagccactg ggatgtcctc caggcacctg   2340
ggtcccatga ccagctcccc gtctccatag gggtaggcat ttcactggtt tatgaagctc   2400
gagtttcatt aaatatgtta agaatcaaag ctgtctttgt tcaggctgct ataacaaaaa   2460
tataatagcc tgggtggctt aacaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2520
aaaaaaaaaa agagggggga g                                             2541

<210> 1335
<211> 1360
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1353)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1360)
<223> n equals a,t,g, or c

<400> 1335
tgctggtacg cctgcaggta ccggtccgga attcccgggt cgacccacgc gtccggataa     60
gagagcggtc tggacagcgc gtggccggcg ccgctgtggg gacagcatga gcggcggttg    120
gatggcgcag gttggagcgt ggcgaacagg ggctctgggc ctggcgctgc tgctgctgct    180
cggcctcgga ctaggcctgg aggccgccgc gagcccgctt tccaccccga cctctgccca    240
ggccgcaggc cccagctcag gctcgtgccc acccaccaag ttccagtgcc gcaccagtgg    300
cttatgcgtg cccctcacct ggcgctgcga cagggacttg gactgcagcg atggcagcga    360
tgaggaggag tgcaggattg agccatgtac ccagaaaggg caatgcccac cgccccctgg    420
cctcccctgc ccctgcaccg gcgtcagtga ctgctctggg ggaactgaca agaaactgcg    480
caactgcagc cgcctggcct gcctagcagg cgagctccgt tgcacgctga gcgatgactg    540
cattccactc acgtggcgct gcgacggcca cccagactgt cccgactcca gcgacgagct    600
cggctgtgga accaatgaga tcctcccgga aggggatgcc acaaccatgg ggccccctgt    660
gaccctggag agtgtcacct ctctcaggaa tgccacaacc atggggcccc ctgtgaccct    720
ggagagtgtc ccctctgtcg ggaatgccac atcctcctct gccggagacc agtctggaag    780
cccaactgcc tatggggtta ttgcagctgc tgcggtgctc agtgcaagcc tggtcaccgc    840
caccctcctc cttttgtcct ggctccgagc ccaggagcgc ctccgcccac tggggttact    900
ggtggccatg aaggagtccc tgctgctgtc agaacagaag acctcgctgc cctgaggaca    960
agcacttgcc accaccgtca ctcagccctg ggcgtagccg gacaggagga gagcagtgat   1020
gcggatgggt acccgggcac accagccctc agagacctga gctcttctgg ccacgtggaa   1080
cctcgaaccc gagytcctgc agaagtggcc ctggagattg agggtccctg gacactccct   1140
atggagatcc ggggagctag gatggggaac ctgccacagc cagaactgag gggctggccc   1200
caggcagctc ccagggggta gaacggccct gtgcttaaga cactcctgct gccccgtctg   1260
agggtggcga ttaaagttgc ttcacatcct caaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1320
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aanggggggn                         1360

<210> 1336
<211> 2458
<212> DNA
<213> Homo sapiens

<400> 1336
cggccacgaa ccgcgtagtt gcgcccaccc cgggacccgg gacccctgcs gagcgccacg     60
ccgacggctt ggcgctcgcc ctggagcctg ccctggcgtc ccccgcgggc gccgccaact    120
tcttggccat ggtagacaac ctgcaggggg actctggccg cggctactac ctggagatgc    180
tgatcgggac ccccccgcag aagctacaga ttctcgttga cactggaagc agtaactttg    240
ccgtggcagg aaccccgcac tcctacatag acacgtactt tgacacagag aggtctagca    300
cataccgctc caagggcttt gacgtcacag tgaagtacac acaaggaagc tggacgggct    360
tcgttgggga agacctcgtc accatcccca aaggcttcaa tacttctttt cttgtcaaca    420
ttgccactat ttttgaatca gagaatttct ttttgcctgg gattaaatgg aatggaatac    480
ttggcctagc ttatgccaca cttgccaagc catcaagttc tctggagacc ttcttcgact    540
ccctggtgac acaagcaaac atccccaacg ttttctccat gcagatgtgt ggagccggct    600
tgcccgttgc tggatctggg accaacggag gtagtcttgt cttgggtgga attgaaccaa    660
gtttgtataa aggagacatc tggtataccc ctattaagga agagtggtac taccagatag    720
aaattctgaa attggaaatt ggaggccaaa gccttaatct ggactgcaga gagtataacg    780
cagacaaggc catcgtggac agtggcacca cgctgctgcg cctgccccag aaggtgtttg    840
atgcggtggt ggaagctgtg gcccgcgcat ctctgattcc agaattctct gatggtttct    900
ggactgggtc ccagctggcg tgctggacga attcggaaac accttggtct tacttcccta    960
aaatctccat ctacctgaga gacgagaact ccagcaggtc attccgtatc acaatcctgc   1020
ctcagcttta cattcagccc atgatggggg ccggcctgaa ttatgaatgt taccgattcg   1080
gcatttcccc atccacaaat gcgctggtga tcggtgccac ggtgatggag ggcttctacg   1140
tcatcttcga cagagcccag aagagggtgg gcttcgcagc gagcccctgt gcagaaattg   1200
caggtgctgc agtgtctgaa atttccgggc ctttctcaac agaggatgta gccagcaact   1260
gtgtccccgc tcagtctttg agcgagccca ttttgtggat tgtgtcctat gcgctcatga   1320
gcgtctgtgg agccatcctc cttgtcttaa tcgtcctgct gctgctgccg ttccggtgtc   1380
agcgtcgccc ccgtgaccct gaggtcgtca atgatgagtc ctctctggtc agacatcgct   1440
ggaaatgaat agccaggcct gacctcaagc aaccatgaac tcagctatta agaaaatcac   1500
atttccaggg cagcagccgg gatcgatggt ggcgctttct cctgtgccca cccgtcttca   1560
atctctgttc tgctcccaga tgccttctag attcactgtc ttttgattct tgattttcaa   1620
gctttcaaat cctccctact tccaagaaaa ataattaaaa aaaaaacttc attctaaacc   1680
aaaacagagt ggattgggct gcaggctcta tggggttygt tatgccaaag tgtctacatg   1740
tgccaccaac ataaaacaaa accaagcctt ggctcgttct cttctctctt caatctctgg   1800
aaaaataagt acatatagtt gataacccct cttagcttac aggaagcttt ttgtattaat   1860
tgcctttgag gttattttcc gccagacctc aacctgggtc aaagtggtac aggaaggctt   1920
gcagtatgat ggcaggagaa tcagcctggg gcctggggat gtaaccaagc tgtacccttg   1980
agacctggaa ccagagccac aggccccttt tgtgggtttc tctgtgctct gaatgggagc   2040
cagaattcac taggaggtca tcaaccgatg gtcctcacaa gcctcttctg aagatggaag   2100
gccttttgcc cgttgaggta gaggggaagg aaatctcctc ttttgtaccc aatacttatg   2160
ttgtattgtt ggtgcgaaag taaaaacact acctcttttg agactttgcc cagggtcctg   2220
tgcctggatg ggggtgcagg cagccttgac cacggctgtt cccctcaccc aaaagaatta   2280
tcatcccaac agccaagacc caacaggtgc tgaactgtgc atcaaccagg aagagttcta   2340
tccccaagct ggccactatc acatatgctt actcttgctt aaaattaata aatcatgttt   2400
tgatgagaaa aaactaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa     2458

<210> 1337
<211> 1839
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1014)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1017)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1205)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1689)
<223> n equals a,t,g, or c

<400> 1337
aaccagcatt tgatcccgag aaaggaactt caacactttg ttttgcagct gcggcactgg     60
cgggaatact ggaatgagca gagtgcaaag cggagagtcc cagccacacc cagactacca    120
gccaggctca tcaagaggga atctggttac catgaaaatg gagtggtgaa ggcagagaay    180
ggaacctccc cacggactaa gaaactcaag tctccctarg gccaaagtgc taagaacagg    240
aatcctcttg gtgggggccg gcaggggcaa gagcccaggc cccctccctg cctcctcctt    300
cctgcctgtr atgctccgtc tcaaacagcc gaaacctgtc ttgcaatggg gggagggggc    360
gtttcrcttt ccttcttctt ggcttcctct tattcttcca caaaccattc tcaataaagc    420
caaaaatctt tctctttctc cccctcaggc cacctcctgt cctactcctg cctgtgctgg    480
cttttctgga acgccakgcg cccatggctg gcacctttct gcttgctctg kctcttgcct    540
tatggctgct gcttttcctt tttacttcct attttcacct tatcttgcaa ttttyctgtc    600
tgatttttac aatgggaggg gagctaagat tgcagtcctg tccttcggtc ccccagggcc    660
tgccggtcag aagcctgggg ctggtaggcc ttggtggtcc tcatgtggat gggcaagaag    720
agagcggcca tctcggatca taatctcctt ggtgctgatt aactgacgag atatatgatt    780
ccagttctgc atgtaccatc ttgaggcaca gcagccactg ctcgttgtaa atgccaaggc    840
atttggcttt gggacgtgac aactcaatcc agaaggatgg tgtgaactcg gttgggtccc    900
gtgactcgag ctcctaccag tggctggccg cggattggaa gccagcctgc tgtcgctctg    960
tgggggggac atgtcttccc actgcttaga gcgagagcag agcaaactgc gcanagncac   1020
ctccagaaag gtaatggtgg cagaacccac agtggagtcg acctaggcct ttctccagca   1080
gtcccagtyg ccattgcttt ttcagccatt cacaagcatt caaaaccaaa ccaaacagca   1140
gttcatatac ctgcctgaga taggctggtc ctcacctcca gagccagcca gccccgtcag   1200
gggcnaaact tactaccttg acttcatctc tagctgcaga aacactaagt ctcaagggct   1260
tcagccccat gctggtccct tggtgttcag ggagggtcac ttggaccgct gttcatctgg   1320
ccgcccttgt tgagtgttct ttggaattgt cgttttttga gcacaactac agcattttag   1380
actgcatgaa accatgactg actgagagtc actctctggg tagatgatag gcgcctttct   1440
ggccccttcc ctcacagatt ctttcccctc ccctccacct gaagagaagg cctccaagtc   1500
cttttggtgc cttgtgagga cttttagaag gggcgttcag ctttaaaaag ccggtcctaa   1560
ttacggccgg acgcagtagc ttacgcctgt tatcccagca ctttgggagg tcgaggtggg   1620
cagatcacct gaggttagga gttcaagacc agcctggcca acatggtgaa accccatctt   1680
taytaaaant acaaaaaatt aggtgtagtg gcaggcacct gtaatcccag ctactcggga   1740
ggctgaggca ggagaatcgc ttgaacctag aaggtggagg ttgcagtgag cggagattgt   1800
accatggcac tccagcctgg gacaacaaga gcgaaattt                          1839

<210> 1338
<211> 1380
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1051)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1208)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1370)
<223> n equals a,t,g, or c

<400> 1338
ggcggcgggc cggcgggcgg accgggccgg tgctggagaa gtttgcgctg cggttcgtga     60
gcgcagggtg cgggccccgc cggccgctgc gcgcccgctg ccatggcttt ccgcaggagg    120
acgaaaagtt acccgctctt cagccaggag ttcgtcatcc acaaccatgc ggacatcggc    180
ttctgcctgg tgctctgcgt cctcatcggg cttatgttcg aggtcacagc caagactgcc    240
tttctattta ttttacctca gtataacatt agcgtgccta cagcagacag tgagaccgtg    300
cactaccact atggccctaa ggacctggtc acaatcttgt tctacatctt catcaccatc    360
atcttgcatg ctgtggttca ggagtacatt ttagataaaa tcagcaaacg gcttcatctc    420
tccaaagtca aacacagcaa gttcaatgaa tctggacagc tggtcgtctt tcatttcacc    480
tcggtgattt ggtgcttcta cgtggtggtg acggaaggat acttaacaaa cccaagaagc    540
ctctgggaag actacccgca tgtgcacctc cccttccagg tgaagttttt ctacctatgc    600
cagctggcct actggctgca cgcacttcct gagctatact tccagaaggt acggaaggag    660
gaaattcccc gccagctcca gtatatttgc ctgtacctgg tgcatatagc tggagcatac    720
ctcttaaacc tgagccgcct gggcctgatc ttgctgctgc tgmagtactc aactgagttc    780
ctcttccaca cggstagact cttctacttt gcagatgaaa acaacgagaa actgttcagt    840
gcctgggctg ctgkttttgg ggttacccgs ctcttcatcc tcacccttgc cgtgctggcc    900
attggctttg gactggctcg catggaaaac caggcatttg atcccgagaa agggaacttc    960
aacactttgt tttgcaggct ctgcgtgctg ctgctggtgt gtgccgccca ggcctggctc   1020
atgtggcgct tcatccactc ccagctgcgg nactggcggg aatactggaa tgagcagagt   1080
gcaaagcgga gagtcccagc cacacccaga ctaccagcca ggctcatcaa gagggaatct   1140
ggttaccatg aaaatggagt ggtgaaggca gagaacggaa cctccccacg gactaagaaa   1200
ctcaagtntc cctaaggcca aagtgctaag aaacaggaat cctcttggtg ggggccgagc   1260
agggggcaag gwgcccaggc cccctccctg gcctcctcct tcctgcctgt gaatgcttcc   1320
gttttcaaac agccgaaacc tgttttgcaa tggggggagg gggcgttttn ggttttcctt   1380

<210> 1339
<211> 881
<212> DNA
<213> Homo sapiens

<400> 1339
ccacatacaa agaggaaaga tgaaactttt wttgttacat ttattgacac tggatattta     60
ttatctgtta tataccaggc aaaatggaca caccatcagg agataagacc tgtatcttac    120
gtgtaagatg aaacttatat ttattgattg aattattgaa tactttttga gtatttgcta    180
tataccaggc aaaaggcaca gaacaaatta tttgttcaca gttactttta actctttcag    240
caatgcctga gtcctcttta tagaaacttc attttgctaa gttagcaacc attcattttt    300
ttggttactc ttcatgtata gttttctcaa gtgtctcttc aaatactgca taatggtata    360
gaccatttaa tattccaaac ataatctgaa agactagagg aatcgccatt aatttcattt    420
gtgtttgaca aagcgtcatc caatggatta aaacccttcc ttttggtggc agtggaacgg    480
tatgatactt ggttgccagg cgtccatttt tagtaaaagc caaagaactg ggatagaaaa    540
caccacaaac tatgccaatc agtgagcttc tgaaaacaca gttttccttg cttatattat    600
ctgaatacaa agcatcaatt acaaaaagct tgtcagtaac aacagtagac aaaaatggaa    660
gtgtagccaa tgatgcatat gtcttcaaag catcatgttt aaccttgaag cagcgtctga    720
acaggaagtt tgagaatatt ccagagaaac cagctgttgt tccaaatgtc gccatttgat    780
atatattttg tgtccttggg cgcttcctca gttcccaccg gcaccacacc tgaatccctt    840
ggcttagtcc cagcctcata cccgaacacc accattttgg c                        881

<210> 1340
<211> 1022
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (931)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (956)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (968)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (990)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1015)
<223> n equals a,t,g, or c

<400> 1340
gcaccaaaat ggtggtgttc gggtatgagg ctgggactaa gccaagggat tcaggtgtgg     60
tgccggtggg aactgaggaa gcgcccaagg aaatgaaaca cgatttccaa aatgaactta    120
atctttcatg agaaactgag gatagagatg tcaataagca gccactgttt ccacctcccc    180
acctgaagag ctaggaggac aactacaaag agcctgactg ccttctcgga atgaggagag    240
aggaaaacag caacagtatc agttttcaag atggcagcat ctatgcatgg tcagcccagt    300
ccttctctag aagatgcaaa actcagaaga ccaatggtca tagaaatcat agaaaaaaat    360
tttgactatc ttagaaaaga aatgacacaa aatatatatc aaatggcgac atttggaaca    420
acagctggtt tctctggaat attctcaaac ttcctgttca gacgctgctt caaggttaaa    480
catgatgctt tgaagacata tgcatcattg gctacacttc catttttgtc tactgttgtt    540
actgacaagc tttttgtaat tgatgctttg tattcagata atataagcaa ggaaaactgt    600
gttttcagaa gctcactgat tggcatagtt tgtggtgttt tctatcccag ttctttggct    660
tttactaaaa atggacgcct ggcaaccaag taagttcttc cttttccttc ttttttcttt    720
wcttttcttt tctttttttt ttttttttag gttaataaac tctctttctt ctttagctgt    780
ctatgatata tttgaatcaa aatgtggtag tttggtattt cagatagcta acttttaact    840
tttttgctct ctacattata gatctagaaa ggcaattatc aatttaggag aagtcaacaa    900
acttctaata gcattcatat ccaggagagg ngattaactc ttttttcttt ttaggnatca    960
taccggtnca ctggcaccaa aaggaagggn tttaatccat tggatgacgc tttgncaaac   1020
ac                                                                  1022

<210> 1341
<211> 1038
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> n equals a,t,g, or c

<400> 1341
aggtaccctc tggaaacccg ggtcgacccn cgcgtccgcg acaactgcgc gccactccgc     60
ggcctaccgc gcagatcctc tacgtgtgtc ctcgcgagac aagctcaccg aaatggccgc    120
gtccagtcaa ggaaactttg agggaaattt tgagtcactg gaccttgcgg aatttgctaa    180
gaagcagcca tggtggcgta agctgttcgg gcaggaatct ggaccttcag cagaaaagta    240
tagcgtggca acccagctgt tcattggagg tgtcactgga tggtgcacag gtttcatatt    300
ccagaaggtt ggaaagttgg ctgcaacagc tgtgggaggt ggattttttc tccttcagct    360
tgcaaaccat actgggtaca tcaaagttga ctggcaacga gtggagaagg acatgaagaa    420
agccaaagag cagctgaaga tccgtaagag caatcagata cctactgagg tcaggagcaa    480
agctgaggag gtggtgtcat ttgtgaagaa gaatgttcta gtaactgggg gatttttcgg    540
aggctttctg cttggcatgg catcctaagg aagatgacct catgttcatt gttcctggtt    600
ttttccagcc agcagcctct acactccatc ataggacatc gagtccctcc tcctcttctc    660
ccatgccttc ttccctgcca tggcaaatct gagtggcttc tctaagcatc tgctggtaca    720
agtcaatgtg gcaccatgag cttcatggtg gcagaagaga caatagtcct tagctctcct    780
cccagtacac cccctacttg gccagtctgt aggccaacaa gaaggttcct ttacccccat    840
gcaagacact tatgagaaca cattacaaga tggctgaccg tggaggatga gtggatcctg    900
aaaggttgtc ccaaactgtt gatttggaaa agaaataagc acatagataa ccttattgtg    960
tgctgcatgg aaaggaactg aatacatttg cctttaagca tgaaaaaaaa aaaaaaaaaa   1020
aaaaaaaaaa aaaaaaaa                                                 1038

<210> 1342
<211> 1121
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (231)
<223> n equals a,t,g, or c

<400> 1342
gatacctccc cttctggctg gtgcgatggc tgctgttccg cctcatgttc gcctcaggcg     60
tggtcaagct gaccagccgc tgccctgcgt ggtgggggct cactgccctc acctaccact    120
acgagaccca gtgcctgccc acgcccgccg cctggttcgc acaccacctg ccggtctggc    180
tgcacaagct cagcgtggtg gccaccttcc taattgagat cgctgtgccg nccctgttct    240
tcgyccccat tcgacgcctg cgcttggctg ctttctactc gcaggtgctg ctgcaggtcc    300
tgattatcat caccggcaac tacaacttct tcaacctgat gacgctggtg cttaccactg    360
cgctgttgga cgaccagcac ctggctgctg agcctggcca cggcagccgc aagaagacgg    420
ccacctcctg gcccaaggsc ctgctggcca ccctgtcgct gctgctggaa ctagccgtct    480
acgggcttct ggcctatggc actgtgcact actttggcct ggaggttgac tggcagcagc    540
gcaccatcca ctccagaacc actttcacct tccaccagtt ttctcagtgg ctgaagacac    600
tgacgctgcc cactgtgtgg ctgggtgtgg cctccctggt ctgggagctg ctgagtgccc    660
tgtggaggtg gacccaggtg cggggctggc tacggaagct cagtgctgta gtccaactgt    720
cccttgtggg cactgcgacc gtggccttgt tcctgattag cctggtgccg tactcctacg    780
tggagcccgg gacccacggg cgcctctgga ccggggccca ccgcctgttt ggtgccgtgg    840
agcamctaca gctggccaac tcctacggcc tcttccgccg catgactggg cttggtggac    900
ggcctgaggt ggtgctggag ggcagttacg acggccacca ctggayggag atcgagttca    960
tgtacaagcc tgggaacctg agccggccgc ccccggttgt ggtgccccac cagccacgcc   1020
tggtactggc agatgtggtt tgcagccctg ggcccacaca cgcacagccc gtggttcaca   1080
agcctggtct tgcgcctgct gcagggcaag gtagccagtg a                       1121

<210> 1343
<211> 1013
<212> DNA
<213> Homo sapiens

<400> 1343
atctggttga actacttaag cttaatttgt taaactccgg taagtaccta gcccacatga     60
tttgactcag agattctctt ttgtccacag acagtcatct caggagcaga aagaaaagag    120
ctcccaaatg ctatatctat tcaggggctc tcaagaacaa tggaatatca tcctgattta    180
gaaaatttgg atgaagatgg atatactcaa ttacacttcg actctcaaag caataccagg    240
atagctgttg tttcagagaa aggatcgtgt gctgcatctc ctccttggcg cctcattgct    300
gtaattttgg gaatcctatg cttggtaata ctggtgatag ctgtggtcct gggtaccatg    360
ggggttcttt ccagcccttg tcctcctaat tggattatat atgagaagag ctgttatcta    420
ttcagcatgt cactaaattc ctgggatgga agtaaaagac aatgctggca actgggctct    480
aatctcctaa agatagacag ctcaaatgaa ttgggattta tagtaaaaca agtgtcttcc    540
caacctgata attcattttg gataggcctt tctcggcccc agactgaggt accatggctc    600
tgggaggatg gatcaacatt ctcttctaac ttatttcaga tcagaaccac agctacccaa    660
gaaaacccat ctccaaattg tgtatggatt cacgtgtcag tcatttatga ccaactgtgt    720
agtgtgccct catatagtat ttgtgagaag aagttttcaa tgtaagggga agggtggaga    780
aggagagaga aatatgtgag gtagtaagga ggacagaaaa cagaacagaa aagagtaaca    840
gctgaggtca agataaatgc agaaaatgtt tagagagctt ggccaactgt aatcttaacc    900
aagaaattga agggagaggc tgtgatttct gtatttgtcg acctacaggt aggctagtat    960
tatttttcta gttagtagat ccctagacat ggatcagggg cagccaagct tga          1013

<210> 1344
<211> 2132
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1424)
<223> n equals a,t,g, or c

<400> 1344
ggcacctaaa ctctcaggta aagaaaacca ctacaaggtg gtgtcatatt gtgcgggatt     60
cagatagtct ggctgaatca gaatttgaat cagcagcctt cagccagggc tctagatcgg    120
gtgtgagtgg tggctctcga agcctcaaca tgtcaagaag agactcagaa agcacccgcc    180
atgactcgga gactgaggac atgttatggg acgacctgct acatggccca gagtgccggt    240
catctgtcac cagtgacagt gagggggccc atgtgaatac ccttcactca gggaccaaac    300
gtgaccccaa agaggatgtt tttcagcaga atcatttatt ctggcttcag aattcaagtc    360
cttcctctga tcgagttagt gcaataatct gggaggggaa tgagtgcaaa aagatggata    420
tgtctgtgtt ggaaataagt ggcatcatca tgagcagggt caatgcctat cagcaaggag    480
taggttatca gatgctggga aatgttgtca ctattggatt agcatttttt ccattcttac    540
atcgactttt ccgtgagaag agccttgacc aactaaagtc catttcagct gaggagatct    600
tgactctctt ttgtggggca ccacctgtta cacctattat tgttttgtcg ataattaatt    660
tttttgaaag attgtgtctt acttggatgt tttttttcat gatgtgtgtg gcagagagaa    720
catataaaca gagattttta tttgcaaaac tcttcagcca tattacttct gccaggaaag    780
ctaggaaata tgaaatacct catttcagac ttaagaaggt ggagaatatt aaaatatggt    840
tatcactgcg ttcctatcta aagagacggg ggccacagcg ttcagttgat gtggttgtat    900
cctcggtttt cctactgaca ctttcgattg ctttcatttg ttgtgctcag gttctccaag    960
gacataaaac tttcctgaat gatgcttata actgggagtt tttgatctgg gaaacagctt   1020
tactactttt tttattgcgt ctggcctcac tggggtctga aaccaataag aaatacagca   1080
atgkttcaat attacttaca gaacagatta atttatatct taagatggaa aaaaagccaa   1140
ataagaaaga acagcttact ctagtaaaca atgtattaaa gctgtccacc aagttgttga   1200
aagagctgga cacaccattt agactctatg gactgacaat gaatccctta atctacaata   1260
tcacaagagt agttatcctt tctgctgtct caggtgktat aagtgatctt ctaggattta   1320
atataagamt gtggaaaatt aaatcataag ctgagttaaa tgcctggact ctcccctggc   1380
tggtatcaaa acttacctat caaggaaagt gatgactgca gaanccagtg agatacccac   1440
ctgcttgttc acatgcacag gtgctctcag ctctgccaaa gcgaatgaat ggtgtttccg   1500
gaggagcaag tccttttcca actgggtgtg catgctaaaa acctgtattt tcatgctttt   1560
caaacaacat gaatagtcag ctgactaaag actgtgtgtg ttgtggtaac acaaagacaa   1620
ttttgtaagt ttgcgcttca gtactgtgac agttatgttt actggacata gtcttttggg   1680
caactatgat agatgcccaa agcatgaagc aaatatcttt tattggaaat atgcaaattc   1740
aatacttttc cattatagtc tatagaactg gagatttcat ttctctatca aagagagatc   1800
aagcgaacta ttttaggtta aatccgaata aaagaacttt actggagact ttcagtttct   1860
aggttttctt tgttgttgaa ggaagaaaat taacttttaa actgtgagtt tctgttaaac   1920
tgtggagaaa tgttttgttc gtttacgatt ttgggttaat aactgtatag ttgttggcaa   1980
acgatgcatg catacaatat gccatgtaat tcagcatgaa aaatttaagt atatgcctac   2040
tcatccattt ccatcataca acatggtttc cacgttctat gtggaagcca tggaagcatt   2100
gtttccatat agatcatctg agttgtggtt cc                                 2132

<210> 1345
<211> 1602
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1579)
<223> n equals a,t,g, or c

<400> 1345
cttgggngaa agagaattca tttttaaaaa aaaaaaaaaa gtgaaggaag gagacagcag     60
attggaaata acactggagt ggatgggatg tcctcttccc tragggggcc ggggtaccag    120
acgggaggct gggagaggat gagaggctgc cccatggctg gaggcagcgt ccgtgtgtgc    180
agtcaccatc atcaaccccc attcggcccc ttccccagat gcgctggtga caggggcttc    240
ttggatgtca aatcatgttg taggagggtg cagactgcgg gcttctgtgg ggagcagtac    300
tactgtgtct gtcggcagtg gccatgggac cctcagcccg tcctgtacat ggagcagggt    360
gcacagtcac cctccatcct gtggcgagag gctggcccgg cccggccagg cgaggcagaa    420
ggtgtcggcc aagtggcccc gaccccatcc cgcaatctct cagctgcttt ttattacctt    480
tgtgccccat ttgggagttt gcttcctcca cctggacact ttgcccggga ggtcatcaga    540
gcccaacccc aggctctgct cggttggaga ggggatgact tcaccaccac ctgaccttcc    600
tagggtcctg gtctcactgt cagctggggg tccgttgtgt gtatttgtac agttttgctg    660
tatggggttt gtcacccaaa agctgatgct gagaaaggcc tccctggggc ccctcccgcg    720
ggcatctgag agacctggtg ttccagtgtt tctggaaatg ggtcccagtg ccgccggctg    780
tgaagctctc agatcaatca cgggaagggc ctggcggtgg tggccacctg gaaccaccct    840
gtcctgtctg tttacatttc actatcaggt tttctctggg cattacgatt tgttccccta    900
caacagtgac ctgtgcattc tgctgtggcc tgctgtgtct gcaggtggct ctcagcgagg    960
tacggggagg gcgtcaccct gcagaacggc agagtgacgc gtcctctcgc tgctgagcac   1020
cagctgttta cctgccctgc atcacttcct cggatacttt actcaataag catttcccct   1080
ggagtgtccg tgccctggtg ttttttatcg atacgttgat taaaacgcgt ggttccccgt   1140
gtgcctgaag cagacattgc tgtgaaatct tttatttttg ttttatgaca cagcatcaat   1200
ttcatgaata ctttgaaagg gccattagaa aaaataagag ccaatttggg tcatttgaga   1260
aacattttca gcacaattac agtgggggca cgggccgttc ggctccagct gggttttccc   1320
agatgcaaca atcgcggttc tggcttctcc actggtgggg atggggatcg cgccttcgga   1380
gctctcaggg cgcctgtctg tcgggggctg ggtgcgtcca cagccccggg ggatggcgcg   1440
tggcgtagcc caggaacggc atgtgggtgg gtctctgacc tgcttgtgca gggacttgag   1500
ggacctcatc ccgatggccg aggcaggggc tycccacggg ataaaaggat ccggcctggc   1560
cttggggtcc aagaggagng ccaagggagt ggacctggcc cc                      1602

<210> 1346
<211> 1483
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1141)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1414)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1429)
<223> n equals a,t,g, or c

<400> 1346
ggcacgaggt cgccgccgcg gccgcctgga attgtgggag ttgtgtctgc cactcggctg     60
ccggaggcga aggtccctga ctatggctcc ccagagcctg ccttcatcta ggatggctcc    120
tctgggcatg ctgcttgggc tgctgatggc cgcctgcttc accttctgcc tcagtcatca    180
gaacctgaag gagtttgccc tgaccaaccc agagaagagc agcaccaaag aaacrgagag    240
aaaagaaacc aaagccgagg aggagctgga tgccgaagtc ctggaggtgt tccacccgac    300
gcatgagtgg caggcccttc agccagggca ggctgtccct gcaggatccc acgtacggct    360
gaatcttcag actggggaaa gagaggcaaa actccaatat gaggacaagt tccgaaataa    420
tttgaaaggc aaaaggctgg atatcaacac caacacctac acatctcagg atctcaagag    480
tgcactggca aaattcaagg agggggcaga gatggagagt tcaaaggaag acaaggcaag    540
gcaggctgag gtaaagcggc tcttccgccc cattgaggaa ctgaagaaag actttgatga    600
gctgaatgtt gtcattgaga ctgacatgca gatcatggta cggctgatca acaagttcaa    660
tagttccagc tccagtttgg aagagaagat tgctgcgctc tttgatcttg aatattatgt    720
ccatcagcaa ccccaaggtc caggtggagg ccatcgaagg gggagccctg cagaagctgc    780
tggtcatcct ggccacggag cagccgctca ctgcaaagaa gaaggtcctg tttgcactgt    840
gctccctgct gcgccacttc ccctatgccc agcggcagtt cctgaagctc ggggggctgc    900
aggtcctgag gaccctggtg caggagaagg gcacggaggt gctcgccgtg cgcgtggtca    960
cactgctcta cgacctggtc acggagaaga tgttcgccga ggaggaggct gagctgaccc   1020
aggagatgtc cccagagaag ctgcagcagt atcgccaggt acacctcctg ccaggcctgt   1080
gggaacaggg ctggtgcgag atcacggccc acctcctggc gctgcccgag catgatgccc   1140
ntgagaaggt gytgcagaca ctgggcgtyc tcctgaccac ctgccgggac cgctaccgtc   1200
aggaccccca gctcggmagg acactggcca gcctgcargc tgagtaccag gtgctggcca   1260
gcctggagct gcaggatggt gaggacgagg gctacttcca ggagctgctg ggctctgtca   1320
acagcttgct gaaggagctg agatgaggcc ccacaccagg actggactgg gatgccgcta   1380
gtgaggctga ggggtgccag cgtgggtggg cttntcaggc aggaggacnt cttggcagtg   1440
ctggcttggc cattaaatgg aaacctgaag gccaaaaaaa aaa                     1483

<210> 1347
<211> 1474
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (942)
<223> n equals a,t,g, or c

<400> 1347
gcacgcagtt cttgggtctg tgctgctggc ctggggttgt ggttgaggcc gggtctccgc     60
tcctgtgccc gggaagatgg tgctaggtgg ttgcccgaat cacgccattt tttaacatct    120
ctttttgatc aaacaagaaa argcatttgg gaaatgcaaa gaggactgag aatactttgg    180
cttaaatttt gcccccagaa tcttgttgtt tgcctactga agagatgaaa ccatggcaga    240
agtagaatcc ttatagaaac aggaccagaa acacctccct tctccaacaa aaggttcatt    300
ttggtggctg tccgtttgac ctgctgtgct tcagtttaat tggcttggaa aggggtcagc    360
agggtgaaac cgaaccccag aaaacttgat gaagaaatgt cttttgcccg ttttgattac    420
gtgcatgcaa acagcgattt gcaaagaccg tatgatgatg atcatgatct tactggtgaa    480
ttacagacct gatgaattta tagaatgtga agacccagtg gatcatgttg gaaatgcaac    540
tgcatcccag gaacttggtt atggttgtct caagttcggc ggtcaggcct acagcgacgt    600
ggaacacact tcagtccagt gccatgcctt agatggaatt gagtgtgcca gtcctaggac    660
ctttctacga gaaaataaac cttgtataaa gtataccgga cactacttca taaccacttt    720
actctactcc ttcttcctgg gatgttttgg tgtggatcga ttctgtttgg gacacactgg    780
cactgcagta gggaagctgt tgacgcttgg aggacttggg atttggtggt ttgttgacct    840
tattttgcta attactggag ggctgatgcc aagtgatggc agcaactggt gcactgttta    900
ctaaaaagag ctgccatcat ggcccargga ggcgggtgaa anctccgtct tctgaattca    960
tctctacagg ctcaaaactc ctctttgata tcagacctga tgttattttc cttcttttgg   1020
agggcatttg tttggktaag aaggctyctt tggactttgg aatttcaacc cagattttac   1080
cttgcagacg gaatgacaag caaaaagtgt tgtggggaat caaatttgtt cctttcctca   1140
tgcacaaaac ataaaggata gtggcgagtt tacaagctgt ggatgggttt ccatagtctt   1200
cctttctgta cattgctata tcttcagtcc tttggagcaa gtggacctaa caagttgagc   1260
aaaatgaata tttggatcca tgttcctctt gtgaccctga gtcttcatgc aaggagatct   1320
gaagctgaac aatgaaaatc ttcagcagaa atagaaatgg ccgtggattg taatacacac   1380
tgaaattctg actttctgaa tttaaatgta gaataaattt taccaacttg gaaaaaaaaa   1440
aaaaaaaaaa aaaaaaaaaa aaaaaaaact cgag                               1474

<210> 1348
<211> 839
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (26)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (730)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (734)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (777)
<223> n equals a,t,g, or c

<400> 1348
ngaggtggnc aggggcccan cagccnttca ccaaggagaa ggccagacct tgggctgagg     60
cagcccagca aattggggca gggagggacg ggcctgcccc tgccctgtgc acctcctgaa    120
gggccacgtc tgggtgatgt ccagtgtctg ggctgattct agggtaagga caaatgaaga    180
gtcccctggc agcagggaaa gggcacccca aaatgcgaga tgggaytggc tggcacccac    240
aggacacagg gctgaggaga ggccctgcct tcaccaccca ggcctcagtt cacactctcc    300
ttgggacctg gggtcatgcg tgctgggcaa acccaccacr agcaccctgg catggagaag    360
gggtggcagg aggacgccaa tcaccatgtg accctaggcc tgctggccag gccagcaaca    420
gttcacctgc cctacctgca tctatcagac agccagggat ggcaccagtc attcacctat    480
acatccttat cctatgcttt cagccacgtg tcctctggaa ggaaatcccc acgggcccag    540
ggcactctgc tgtgtcagcg cccacttcct ccaaacagtg gagctggaca ccccgccaca    600
tgctggccct gcctggacca caaggaccac gtggccccac accagcacgg gtgcaccccc    660
gggggctggm acttggttct agctctcact ggaagggtga gtggmgctgc agtttccgtg    720
gaggctctgn cctncgagca tggcgacact taagcaagcg tggcgtgagg gaagcangcg    780
gaacctgggc tggcttcact catacactgg gcctgggccc ttaaccaacc ccggggctg     839

<210> 1349
<211> 4303
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (24)
<223> n equals a,t,g, or c

<400> 1349
ggcacgagca gcagcggcan ggcnggcgcg gagtcccctg cgcccagcgg cccggccggg     60
ctgcggcaga ggcggcggcg gcgccccgct ccgggtgagg ttgccggggc cgtgcgcgct    120
gatctgcgag tgaagaggga cragggaaaa gaaacaaagc cacagacgca acttgagact    180
cccgcatccc aaaagaagca ccagatcagc aaaaaaagaa gatgggcccc ccgagcctcg    240
tgctgtgctt gctgtccgca actgtgttct ccctgctggg tggaagctcg gccttcctgt    300
cgcaccaccg cctgaaaggc aggtttcaga gggaccgcag gaacatccgc cccaacatca    360
tcctggtgct gacggacgac caggatgtgg agctgggttc catgcaggtg atgaacaaga    420
cccggcgcat catggagcag ggcggggcgc acttcatcaa cgccttcgtg accacaccca    480
tgtgctgccc ctcacgctcc tccatcctca ccggcaagta cgtccacaac cacaacacct    540
acaccaacaa tgagaactgc tcctcgccct cctggcaggc acagcacgag agccgcacct    600
ttgccgtgta cctcaatagc actggctacc ggacagcttt cttcgggaag tatcttaatg    660
aatacaacgg ctcctacgtg ccacccggct ggaaggagtg ggtcggactc cttaaaaact    720
cccgctttta taactacacg ctgtgtcgga acggggtgaa agagaagcac ggctccgact    780
actccaagga ttacctcaca gacctcatca ccaatgacag cgtgagcttc ttccgcacgt    840
ccaagaagat gtacccgcac aggccagtcc tcatggtcat cagccatgca gccccccacg    900
gccctgagga ttcagcccca caatattcac gcctcttccc aaacgcatct cagcacatca    960
cgccgagcta caactacgcg cccaacccgg acaaacactg gatcatgcgc tacacggggc   1020
ccatgaagcc catccacatg gaattcacca acatgctcca gcggaagcgc ttgcagaccc   1080
tcatgtcggt ggacgactcc atggagacga tttacaacat gctggttgag acgggcgagc   1140
tggacaacac gtacatcgta tacaccgccg accacggtta ccacatcggc cagtttggcc   1200
tggtgaaagg gaaatccatg ccatatgagt ttgacatcag ggtcccgttc tacgtgaggg   1260
gccccaacgt ggaagccggc tgtctgaatc cccacatcgt cctcaacatt gacctggccc   1320
ccaccatcct ggacattgca ggcctggaca tacctgcgga tatggacggg aaatccatcc   1380
tcaagctgct ggacacggag cggccggtga atcggtttca cttgaaaaag aagatgaggg   1440
tctggcggga ctccttcttg gtggagagag gcaagctgct acacaagaga gacaatgaca   1500
aggtggacgc ccaggaggag aactttctgc ccaagtacca gcgtgtgaag gacctgtgtc   1560
agcgtgctga gtaccagacg gcgtgtgagc agctgggaca gaagtggcag tgtgtggagg   1620
acgccacggg gaagctgaag ctgcataagt gcaagggccc catgcggctg ggcggcagca   1680
gagccctctc caacctcgtg cccaagtact acgggcaggg cagcgaggcc tgcacctgtg   1740
acagcgggga ctacaagctc agcctggccg gacgccggaa aaaactcttc aagaagaagt   1800
acaaggccag ctatgtccgc artcgctcca tccgctcagt ggccatcgag gtggacggca   1860
gggtgtacca cgtaggcctg ggtgatgccg cccagccccg aaacctcacc aagcggcact   1920
ggccaggggc ccctgaggac caagatgaca aggatggtgg ggacttcagt ggcactggag   1980
gccttcccga ctactcagcc gccaacccca ttaaagtgac acatcggtgc tacatcctag   2040
agaacgacac agtccagtgt gacctggacc tgtacaagtc cctgcaggcc tggaaagacc   2100
acaagctgca catcgaccac gagattgaaa ccctgcagaa caaaattaag aacctgaggg   2160
aagtccgagg tcacctgaag aaaaagcggc cagaagaatg tgactgtcac aaaatcagct   2220
accacaccca gcacaaaggc cgcctcaagc acagaggctc cagtctgcat cctttcagga   2280
agggcctgca agagaaggac aaggtgtggc tgttgcggga gcagaagcgc aagaagaaac   2340
tccgcaagct gctcaagcgc ctgcagaaca acgacacgtg cagcatgcca ggcctcacgt   2400
gcttcaccca cgacaaccag cactggcaga cggcgccttt ctggacactg gggcctttct   2460
gtgcctgcac cagcgccaac aataacacgt actggtgcat gaggaccatc aatgagactc   2520
acaatttcct cttctgtgaa tttgcaactg gcttcctaga gtactttgat ctcaacacag   2580
acccctacca gctgatgaat gcagtgaaca cactggacag ggatgtcctc aaccagctac   2640
acgtacagct catggagctg aggagctgca agggttacaa gcagtgtaac ccccggactc   2700
gaaacatgga cctgggactt aaagatggag gaagctatga gcaatacagg cagtttcagc   2760
gtcgaaagtg gccagaaatg aagagacctt cttccaaatc actgggacaa ctgtgggaag   2820
gctgggaagg ttaagaaaca acagaggtgg acctccaaaa acatagaggc atcacctgac   2880
tgcacaggca atgaaaaacc atgtgggtga tttccagcag acctgtgcta ttggccagga   2940
ggcctgagaa agcaagcacg cactctcagt caacatgaca gattctggag gataaccagc   3000
aggagcagag ataacttcag gaagtccatt tttgcccctg cttttgcttt ggattatacc   3060
tcaccagctg cacaaaatgc attttttcgt atcaaaaagt caccactaac cctcccccag   3120
aagctcacaa aggaaaacgg agagagcgag cgagagagat ttccttggaa atttctccca   3180
agggcgaaag tcattggaat ttttaaatca taggggaaaa gcagtcctgt tctaaatcct   3240
cttattcttt tggtttgtca caaagaagga actaagaagc aggacagagg caacgtggag   3300
aggctgaaaa cagtgcagag acgtttgaca atgagtcagt agcacaaaag agatgacatt   3360
tacctagcac tataaaccct ggttgcctct gaagaaactg ccttcattgt atatatgtga   3420
ctatttacat gtaatcaaca tgggaacttt taggggaacc taataagaaa tcccaatttt   3480
caggagtggt ggtgtcaata aacgctctgt ggccagtgta aaagaaaatc cctcgcagtt   3540
gtggacattt ctgttcctgt ccagatacca tttctcctag tatttctttg ttatgtccca   3600
gaactgatgt ttttttttta aggtactgaa aagaaatgaa gttgatgtat gtcccaagtt   3660
ttgatgaaac tgtatttgta aaaaaaattt tgtagtttaa gtattgtcat acagtgttca   3720
aaaccccagc caatgaccag cagttggtat gaagaacctt tgacattttg taaaaggcca   3780
tttcttggga gttttttggt gtgtctgttt ttttaaagta ttcaagatac taccagtcaa   3840
catctttttg gaagaaaatg ccttgggttt agaagatttt cttaaaaggg gagtagatgg   3900
ttgtagattg actaaaaagt ctaccatact tcaagggact acaggtaagt ctcatagtat   3960
accagctttg gtacttcatt ttttaaaaaa gtattaatca attgcaaaga aattcgcctt   4020
ggccaaccct tctttgtgta tcaggtagtc taacctgata caagtagttg acagatttca   4080
actatcaatc accagtccaa cccatttctc atttaacaga tgacggagat aatccctaaa   4140
agcacccaca tttgtttcaa tgccccaaac aggccaaggc tccctagcaa ctccctagtg   4200
gcgtttttta acttctcaga aactgttacc attatttgaa ataggcttcc ttaacctcct   4260
ttacccttaa cccaacaggg atttaaaaaa aaaaaaaaaa aaa                     4303

<210> 1350
<211> 724
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (547)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (565)
<223> n equals a,t,g, or c

<400> 1350
gggccgggcc cctagtgcgg tgttgcggga cggggccgag gcccggtcgg ttggggcgtg     60
ggggcggaga ggatggagcc tccgaggcgt taggcgactc tgtcatctct gggcgtgcag    120
ccgtcgtttc ctggcgcggc ccgtgtgatg gtgccgggag gaaggaagcg cagtgacagc    180
gcctctctca ttcagtcttt gattatacat cagcatcacc agctccctca ccaccaatgc    240
gaccatggga gatgacatca aataggcagc ccccttcagt tcgaccaagc caacatcact    300
tctcagggga acgatgcaac acacctgcac gcaacagaag aagtcctcct gtcaggcgcc    360
agagaggaag aagggatcgt ctgtctcgac ataattccat tagtcaagat gaaaactatc    420
accatctccc ttacgcacag cagcaagcaa tagggagcct cgagccttcc accctccgaa    480
tgtatctccc cgtctgctac atcctgctgc tcatccaccc cagcagaatg cagtcatggt    540
tgacatnaca tgatcaggta caatnaacag aatgtcttgg aaatacagaa gctgaaattt    600
tgtggcagtt tgagattttt tttttgggct ttttgttgca aattctttta rtttttacct    660
aaaatgaagt tatttaagtt cctcattcct tttaagaatt gagatttaaa ttctacacag    720
cttc                                                                 724

<210> 1351
<211> 3963
<212> DNA
<213> Homo sapiens

<400> 1351
cttgtttctg ttttctttag attgtggtat ctgaacggga actatttggt tctgttggtg     60
tcattggtgg tcattcttcc tttgtcgctg tttagaaatt taggatattt gggatatacc    120
agtggccttt ccttgttgtg tatggtgttc tttctgattg tggtcatttg caagaaattt    180
caggttccgt gtcctgtgga agctgctttg ataattaacg aaacaataaa caccacctta    240
acacagccaa cagctcttgt acctgctttg tcacataacg tgactgaaaa tgactcttgc    300
agacctcact attttatttt caactcacag actgtctatg ctgtgccaat tctgatcttt    360
tcatttgtct gtcatcctgc tgttcttccc atctatgaag aactgaaaga ccgcagccgt    420
agaagaatga tgaatgtgtc caagatttca ttttttgcta tgtttctcat gtatctgctt    480
gccgccctct ttggatacct aacattttac gaacatgttg agtcagaatt gcttcatacc    540
tactcttcta tcttgggaac tgatattctt cttctcattg tccgtctggc tgtgttaatg    600
gctgtgaccc tgacagtacc agtagttatt ttcccaatcc ggagttctgt aactcacttg    660
ttgtgtgcat caaaagattt cagttggtgg cgtcatagtc tcattacagt gtctatcttg    720
gcatttacca atttacttgt catctttgtc ccaactatta gggatatctt tggttttatt    780
ggtgcatctg cagcttctat gttgattttt attcttcctt ctgccttcta tatcaagttg    840
gtgaagaaag aacctatgaa atctgtacaa aagattgggg ctttgttctt cctgttaagt    900
ggtgtactgg tgatgaccgg aagcatggcc ttgattgttt tggattgggt acacaatgca    960
cctggaggtg gccattaatt ggcaccactc aaactcaaac tcagtccatc tgatgccagt   1020
gttgagtaaa ctcaactact atgaaatttc acctaatgtt ttcagtttca cttccttttg   1080
aagtgcagat tcctcgctgg ttcttctgag tgcagaataa gtgaactttt ttgttttgtt   1140
ttgttttttt aagaaactta tctgtatgtt agaaatggat atgaacaaca aaaccacgag   1200
tctcgggtta agggaagtga caattttatt ccattccaga gaatggacaa actcttaact   1260
tttatcaagc cacatgcttg gctgtgtcat tgtttaactt ggatatttta tgattttact   1320
tgaatgtgcc taatggaacc atttgatgtg agaaacaatt ctttttaatt tacagcaaaa   1380
tattgaataa ccattgacaa aaacactatt attttttgta ccaaaaatac ttaaagacct   1440
cagaagcact cttttacttt taagaaattg cttttttgaa ctttattcag aagcagttat   1500
caataaattc cataaaataa tgtcattggt atttaaaaat gaatattaat ataatgaaat   1560
ggtttgcctt tttgtaggca taataagcca aatacttttt tacccaaaat aatttttaga   1620
gaaaatgatg taatgaaaaa ttgtaccatg aattaggagc atagtttttt ccatttaaac   1680
gtcaccatta cttaaaagat gattgattat tgctatacca aatcagatga actctgttca   1740
tcacttttct tctctgtccc caaacaattt ggttcattca gactgaaatg tttgtgtctt   1800
caacttatta gaatggaaga taatgcagat atttctgtgg gaaataaaat aactaatttt   1860
gaggtaccaa atagtgcaat tgggtaaaac agggtttatt cagttgcatc tgtctccagt   1920
gttgtattga cagctctggg tctttttttg ggccagccct tttttgacat tgcttccagc   1980
agtggaaaat gggcatttga tggcaatagg ccaaaattat tgtgtccaga gagtacactt   2040
tttcaaaatg ctcacctact ggaagtgtga attacttgac aatgtatggc ttagttgtgt   2100
tcatgttttg tctacagtag aggtctaatc cacaggttac acctatgttt gatatgatat   2160
aagttctctt tgcgtaggcc actgggtttc tcatgcagta agctttataa aaactcattt   2220
gcactggact gtcatctcat tcttgtacaa cgtagaatta cttgtttaca tccaacaaat   2280
ggttagctag ggaaaacagt gcaaactgag tgttagtagt cattttggtc caactgcatg   2340
tcaacccttc catttcaatc ccagttagaa atgaaaataa ttactttgaa acttggcttt   2400
aagagcacat ttatcgtacg tcacagtgta tggtgaatat attattaaat aatgtggtac   2460
ttcgctcatc aggcataatg tctaaaatct aatatacata attccattaa gtggttgaag   2520
gaagcaaata atggaattgt caattggtca tctggctgta aggtttgccc ttgaactaaa   2580
aatgttgttt ggggcaaggg ccagaaatgt ggagacatgg tttttgttac gcattcttgt   2640
attatatgtg actaaattta caaacaagat acatgtgtaa ttaaagaccc ttatggaact   2700
ggaagacgtc ttgtagtgct acattgggtg aaaccgttgg tccatttttg tctgtttcta   2760
tgaagataaa ataattgggg gccatctaga aatagaaagg cagtgggaag acagattcta   2820
cggcactgct ttcatttaat tgggctttag gcactccatt cgaatgcaga acctcacctc   2880
tagttgagac caagaattgg caaatttgca tgagctcctg gaaagagttg ctgactttgt   2940
atctaagacc tgccagggaa taccaagagt tgtttctaca gacttttttt ttttttttgt   3000
atgggagaag atactgtggc aaccaggaag gaatggaaaa aaaattcttt tctctacagc   3060
aaattaatgt gaggaagctc ctccaatcct ctggctattt aaggttcaaa atcaagtgcc   3120
tagggaaaat tccaatggat gattttctgg gagctatctt gtctaccttg aggttcctga   3180
acaatgaatt cccattaatg agcagtcttc agtattaaaa ccactgtctt gtcacctcat   3240
tttgcattac tgtcttccgt ggatgtttca gttacaactg taatgttatt tatagaacaa   3300
cattaatcca ttaaagctaa cctatttttc aatatttatg ataatctatg tacatatatt   3360
gtctgtccat atgtatttgt aaataggttg tatataatgt caggtttggg tcttgggttc   3420
aagtgtatat attcctgtaa gtttcttaac tgcattttga tgaattcaca ttatgtaact   3480
ataagaattg tcccaaaagt acctgtacag aaaattgaat attgaaaaat tgacaaattg   3540
tgtacaaaca ctaaaaaaaa cttgtttaaa ttgtatttgc aataaacaac atcaaatttt   3600
ttcatgaaat cttggtacaa attcagatct cttatttaaa atttaaataa ggaatacatt   3660
ttcaaaatgc agtaatcaaa atgtgatcta gtgtaatgaa ataaaatgtg atctagtgta   3720
atggaagacc tttgagaacc tgggtgtatt aactttgtgt atatagtgta aatatcccca   3780
ctgtactgtt agaggccaac aattctagta tggcttgttg gcaaagagtg ctacaccgtt   3840
tcaatgaaac aatgtatgtt tgttttaact gaactaaaat aaatacatgc ttaatcctga   3900
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaacaa aaaaaaaaaa aaaaaaaaaa   3960
aag                                                                 3963

<210> 1352
<211> 1436
<212> DNA
<213> Homo sapiens

<400> 1352
gccagctgct ggcagagttc ctgtcaaggg atcaagtctt ccaacagaat ggttatggtt     60
taactcagca gaatttgttg aacaactacg acatgctggg gatcatggca tggaatgcaa    120
cttgcaaaaa ctggctggca gcagaggctg ccctggaaaa gtactacctt tccatttttt    180
atgggattga gttcgttgtg ggagtccttg gaaataccat tgttgtttac ggctacatct    240
tctctctgaa gaactggaac agcagtaata tttatctctt taacctctct gtctctgact    300
tagcttttct gtgcaccctc cccatgctga taaggagtta tgccaatgga aactggatat    360
atggagacgt gctctgcata agcaaccgat atgtgcttca tgccaacctc tataccagca    420
ttctctttct cacttttatc agcatagatc gatacttgat aattaagtat cctttccgag    480
aacaccttct gcaaaagaaa gagtttgcta ttttaatctc cttggccatt tgggttttag    540
taaccttaga gttactaccc atacttcccc ttataaatcc tgttataact gacaatggca    600
ccacctgtaa tgattttgca agttctggag accccaacta caacctcatt tacagcatgt    660
gtctaacact gttggggttc cttattcctc tttttgtgat gtgtttcttt tattacaaga    720
ttgctctctt cctaaagcag aggaataggc aggttgctac tgctctgccc cttgaaaagc    780
ctctcaactt ggtcatcatg gcagtggtaa tcttctctgt gctttttaca ccctatcacg    840
tcatgcggaa tgtgaggatc gcttcacgcc tggggagttg gaagcagtat cagtgcactc    900
aggtcgtcat caactccttt tacattgtga cacggccttt ggcctttctg aacagtgtca    960
tcaaccctgt cttctatttt cttttgggag atcacttcag ggacatgctg atgaatcaac   1020
tgagacacaa cttcaaatcc cttacatcct ttagcagatg ggctcatgaa ctcctacttt   1080
cattcagaga aaagtgaggg gcttgtgaaa cagattgttc tacagatgaa tctgtaagcc   1140
agttacagtt tgccttaact catagacatc aatcagagag tgtcacagat ttaaccttga   1200
tctaaagaca agttgtaccc agagtatgtg aaaagaatgg gacgacaaga atgtactggt   1260
ttcttcctct aagaattgaa aggagttgaa ctgccttatg tttgggcatg taactccaaa   1320
atactaggta gtataaggct ttctcaatca gtgcaaaaat ggaagatata taaagcaaca   1380
agttgtctgc atttgatcac tggtcagatt gtaaaaaaaa aaaaaaaaaa ctcgag       1436

<210> 1353
<211> 4412
<212> DNA
<213> Homo sapiens

<400> 1353
ctcgaggtcg acggtatcga taagcttgat atcgtttttt tttgtttgta aaaatgaatt     60
tattaaaatg ctcataatta taaaagaata ttaaaatgca cagaaattaa cattaataat    120
tataaaagaa tattaaaatg cacagaaatt aacattaatt acaaacttta catcttatgc    180
cacaatgtgt gaaaagcatc atgaatagtt ctacttcagt taagctgctc atacattttt    240
accctctcaa acataatatg aacataaaat ggtacaagaa gtgtttcaac aagagtacat    300
tctgaccccc attgtgaatt aatgttttat gaaattcaag gcacacatgc aataaaaaag    360
ggaagacttt ggtgacagtt tataagatgg ccttgtttag ttttaaaata aaaatgatag    420
ctttcccttt ctaatgatat atagctaaat tatctgaggg atgtttaatg aaaaatcccc    480
tgagtatttg ctctaatgtt tcaatatgct aaaattcaca ggcattaaaa aaggatataa    540
agctcagttt ctctagtggt taacactgga caggctgaag gctagattct ccctcttcac    600
aggtccactg ccacacccat caatttcccc agggctgctg cctctgaagc cacttacaga    660
tgcagccacc attgtctgca gacacagctc catgcttttc tttatcactg caagtcagcc    720
gtggactcac taacaaacac tgtggatggc atggggaaat gaccctgcat ctccactaca    780
actttgctct tttgggcatc ttaacagtgt cagatattac atttggtgcc tttcaatatg    840
tagagggttt ttttttccct cctgtccaca gcagcacatt taatctatga agaggatttt    900
ctctgctggg gctatgaaaa caaatgcaca tttcttttaa gttctatcat acatacagga    960
gataaggtaa aaacatttcc ttttctatgc tgacatacat ggcgagtaac tgccaaattt   1020
aaacactagg agatagtcac acacttcaga gaagagaaga ggtactagag aggaagtgac   1080
acccgcttcc agaagcagta tctcaggagt gaagagagga acagtggcac tcccgtcttg   1140
gctgcgaatg agaaagagtt tccttcagtg ggaagaaatt catttctcca tcccagtgca   1200
gtcagacttc atggggcctg tcttgaactc tgattgcatc attaacacga tcaagagaga   1260
cagtgaaatg gggtcccgga tccactggga caattcaaaa gcctacaata ctgctttgat   1320
ggatcctaca taattactta caaatcattc atggcaggca tttgaaatca atcatgacct   1380
agagttacgc tactttattg taaaaagcct ctaaaatctg agttttcctt tgctgctggg   1440
attctgatag gttggctcct ctggtgttta acagcatccc agtgaagccc atgcagcatg   1500
accatgatgc aaatcacctc cctcttgtgc acccagcaat gacctgttac cagtaggggt   1560
gagagggcct ggctccctgt cttttccaga gcgcccagga ggcctgacac ttacaaggca   1620
ataaagtgaa gtagactgct aggctgagca aaagtgaggg ggcaagacgt gcatggcaag   1680
acaggagtgc agcaggaagt aatctccaga taatggtagg gtttgtgacc aaaccctttt   1740
cctttattac tcttaactgc ctgattggct ctagaggagg ctaaaaaatc aaatctaatc   1800
tgagtctctt tacttgatta tgaataagct gggtatactc ctgtctctag tacaatcaga   1860
cagttacatc aaattactgg gcccagagta acaggatgga ggatgcaagg aagccacatt   1920
ctttatggca gagactttgg tgtgttgatc actttggcat acagaaataa gccaattcct   1980
gcagactcct tgacaaaagg cactccccac ccaatgacca caatgagggc acttgctgtt   2040
tctgcccatg cacacagttg taccccaatg gctgtgtagt gagccattca caaaggcagc   2100
tggtgatgtg taatactgca ccttctgtat ctaatgaata aaagtcaact ggtagaaaat   2160
tgaggggctt atcttttcca gacaattatg ttgataaaaa tgtaatttta atcatgtgat   2220
atcactgttt tccaagaaac tacacatctt tagaaaagat taattatcca gatcaacatg   2280
agttaaaatg ctgtttgaat ctgtaacttt ccctgctttt gtcattttat tcccttgaga   2340
tctgcaaagc agtcaacatt gattaggcac ggaacctcct aggagtgctc ctggaagata   2400
aaaagtgtca ctgtggatta ggacaaatat gcttcaaaac cttgctatct tcactccaac   2460
ctactaagag tatttttttg agatggaaag acatgctcaa atgaagactg aaactatttc   2520
ctctgattaa ctgaggtttc ctttctggag gtattgaaaa tacrcctaaa tattgtgaat   2580
ccttgagtct agttagctat ttttaatcac atgmaagcta ttaaattaaa tctataatga   2640
tggtactgta aggaaaagat gaccctggaa cagatctagc caagtgaaga aatgaaacat   2700
ggcttaaaaa taaaggagat catgcgcctg agaatagaca gaaatgaaaa taatcaaaca   2760
gaaaaaaaag aatccattct actttagaag gggtggtttt taagcacact gagggacttt   2820
ttctgtaaaa ttccaattta tcagaaaaag gtaacattga ggttttccgg gtgataagtt   2880
ttatgccctt catgatctaa gttttacatt ttccagtttc tgcatcgcta gctgaaactg   2940
aaaaataata catgaggaaa tggcaatagt tgagactcat atttgccaaa gtgatttaac   3000
ttacacattc tcattagtga ttcctaatat attttgacaa agctaaattc cttaaagtgc   3060
ttctcagaac ataaagctct tattctgatt ttggccgtaa attgttatct actgcttcta   3120
tcrtccgctc agctatcacc cccatatttt tcgtcatatc tttgaggtga ttctcatgaa   3180
gaagcttttg ggttaggtat ttttctctct ggatcttgct ctttgtgcgt tttgatacat   3240
cgggaattgc atatgaaatg aaaaatttca cagagtagat gacgtgctcc atgacaatga   3300
taaaagccag cttggctgca atcacatgcc aatagtagat gttgtgttta tactcctggg   3360
ggtgtccagg tgggtatcgg aaatcacgat acctgcatgt ggtatggtta cccaggtcag   3420
agtacgggtt tcccttgctt ttgtttttga agtctgcgac tttgaagatg gagagagtgt   3480
tgttgatgta cccttccatg gtgtaggaag tgtggtcccc gtagggaggg acggagaagg   3540
accagtagta cactaggcgg gggatcatgt ccgacgtgaa agctatgatc atggcattgg   3600
tcaccacagc cagaattgct attccttgca tgatgggctg ccatgctcca atgtcttggg   3660
ctttctctgg taccaggcgt ctaaactggg tggtcagttt ccatgcgtcc actcttattt   3720
ccaatatatt gttcacgaga gccaacagag gggccagtgg aaaagaggcc acaaataagg   3780
tgacgaaccc aaactgaata atcatttcaa gatattcata aaataatccc agtttgccca   3840
taggctgcag atggtagtcc tgttcccatc gtggggttat cttttctgat ccagaaactc   3900
tgtgaaatcg cccaattaga ttcatgatcc agggcaataa tacttcttgt atgttattcc   3960
agattgcttt tcctcccatg attattgtca gctgagttgt cagttcaaga agacagccac   4020
ctgggtcaca ctcttcattt ctgtattttc ccaaccaata aactgggtct cctggatagc   4080
ctacaaattt gcccttaaag aatgctatgt agaagcatga agaktagtag ttgacaaact   4140
ggaataagaa catcttcatg gtgaggctgt tctcataatc agtctgggtc cttgggagtt   4200
cgaagttagt aatcataatt gccacttttt catatatggt gttcagaatc atgataatta   4260
taaagctgat gatggaggcc gtgatggacg tggctgtctg tggagtcagg tatttctgga   4320
ttgggtctgt tccattaatg ttcttgggaa gttttgcaga aaatacaatg aacaccgaga   4380
gcctatagac aatgatcgga cgcgtgggtc ga                                 4412

<210> 1354
<211> 1520
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1256)
<223> n equals a,t,g, or c

<400> 1354
gccggcccct gcgtgctggg ccaggagcgc ttcacctcag gccgccacta ctgggaggtg     60
gaggttgggg accgcaccag ctgggccctg ggggtgtgca gggagaacgt gaacaggaag    120
gagaagggcg agctgtccgc gggcaacggc ttctggatcc tggtcttcct ggggagctat    180
tacaattcct cggaacgggc cttggctcca ctccgggacc cacccaggcg cgtggggatc    240
tttctggact acgaggctgg acatctctct ttctacagtg ccaccgatgg gtcactgcta    300
ttcatctttc ccgagatccc cttctcgggg acgctgcggc ccctcttctc acccctgtcc    360
agcagcccga ccccgatgac tatctgccgg ccgaaaggtg ggtccgggga caccctggct    420
ccccagtgac tcgggccctc ctggaggagt cctgttgcct ctcctgcccc tccaggccac    480
tgagtgtttt ggccacttgg aggacctggg aggagggagt gtgtcctttg agcaagagga    540
ggaactcctg gtgcctttct gagcctgcgt gggagaaccc caattctagc actccaggaa    600
actgtgggag agtgtggggc aggctccgtc ctccctggga gacccctcca gccaccgggt    660
gccacttaat gccaacagcc cttaccaaag ctgggagccc cattgccccg gcagctctgg    720
cctgtggttc cagaagctga gaaaactcca ctggggcttg cagaatccag ggttcaccta    780
agctgcacag ttcctgcagc tttgccagcc ccctgaaagt cttgtgtacc ccacctctga    840
agatgctggg ggaggcagct gggatgggag ccagccccat gcctgtctgt gaccccacag    900
tgggtgagag cccgtcacag tcctgggtgt ggctgctctg gaagaattag gaggcagcca    960
taataagagt cttcagagag atgatgggag gggccagtga ggacaggaac agagagtaga   1020
tgtcctataa taaaggggct tctgggaggt gcctgggcac agatgtctgt tcagcaggtg   1080
tgtgggccta gaggagagag cagagcccag aaatgtcttt tgcaggccca cgttctgact   1140
tgaagctttc gtgggcatgt tgccattggg ttttgccctt gcaaaggctt cctaggtctc   1200
cagtggcccc tcaggaccca gggtcccagc tgctgcttgg ggatgtgcac tgctgncgcc   1260
ggccttgcag tctctctacc ctggggagga acagtggctt ctcagagcct ggggcataca   1320
gaagaaggca ggagttgatt tttgtgttgg gtttggggtt tctttgtcct caaggtactg   1380
ttctgtttct ctttacccct ctgctttatt tattgtaagc attcccacgt taaataaact   1440
ttggctgttg tctacaagtc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   1500
aataaaaaaa aaaaaaaaaa                                               1520

<210> 1355
<211> 2426
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (8)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (49)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2402)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2413)
<223> n equals a,t,g, or c

<400> 1355
nattgagngc aacnggtaag tcgacgcacg tagtagggga aagcctggnt acgcctgcag     60
gtaccgggtc cgsaattccc ggggtcgacc cacgcgtccg ctgagaataa tggcccggtt    120
ggcccgggac gagtggaatg attaatgatg ttttgcagca gttttctacg tctgaaattt    180
tttatgtctc tggaacccag aatttgctaa gagatggagg aacctcagaa aagctatgtg    240
aacacaatgg accttgagag agatgaacct ctcaaaagca ccggccctca gatttctgtt    300
agtgaatttt cttgccactg ctgctacgac atcctggtta accccaccac cttgaactgt    360
gggcacagct tctgccgtca ctgccttgct ttatggtggg catcttcaaa gaaaacagaa    420
tgtccagaat gcagagaaaa atgggaaggt ttccccaaag tcagtattct cctcagggat    480
gccattgaaa agttatttcc tgatgccatt agactgagat ttgaagacat tcagcagaat    540
aatgacatag tccaaagtct tgcagccttt cagaaatatg ggaatgatca gattccttta    600
gctcctaaca caggccgagc gaatcagcag akgggagggg gattcttttc cggtgtgctc    660
acagctttaa ctggagtggc agtggtcctg ctcgtctatc actggagcag cagggaatct    720
gaacacgacc tcctggtcca caaggctgtg gccaaatgga cggcggaaga agttgtcctc    780
tggctggagc agctgggccc ttgggcatct ctttacaggg aaaggttttt atctgaacga    840
gtaaatggaa ggttgctttt aactttgaca gaggaagaat tttccaagac gccctatacc    900
atagaaaaca gcagccacag gagagccatc ctcatggagc tagaacgtgt caaagcatta    960
ggcgtgaagc ccccccagaa tctctgggaa tataaggctg tgaacccagg caggtccctg   1020
ttcctgctat acgccctcaa gagctccccc aggctgagtc tgctctacct gtacctgttt   1080
gactacaccg acaccttcct acctttcatc cacaccatct gccctctgca agaagacagc   1140
tctggggagg acatcgtcac caagcttctg gatcttaagg agcctacgtg gaagcagtgg   1200
agagagttcc tggtcaaata ctccttcctt ccataccagc tgattgctga gtttgcttgg   1260
gactggttgg aggtccatta ctggacatca cggtttctca tcatcaatgc tatgttactc   1320
tcagttctgg aattattctc cttttggaga atctggtcga gaagtgaact gaagaccgtg   1380
cctcagagga tgtggagcca tttctggaaa gtatcaacgc aggggctttt tgtggccatg   1440
ttctggcccc tcatccctca gtttgtttgc aactgtttgt tttactgggc cctgtacttt   1500
aacccaatta ttaacattga tcttgtggtc aaggaactcc ggcggctgga aacccaggtg   1560
ttgtgactgg cactgcccag gctgagactc ttcaagtccc gctgacgtct gagctttgat   1620
gcttaagagg ggtgaggcag ggagcggact tcctattttc taccctcagt aaaacaaggt   1680
gctgctttgt atatcaaaag ctccaaccat gtcctctccc cctcagcctg tgggtggcac   1740
gagcaaggac tgacatccgc acagggagga ttgtctgttt ggctgacaca gcagcagccc   1800
ttcccaccca gccaccttcc tcacagggac taggaggctc agtccccaac ggctggcaag   1860
actcagggtc ctcagtggac atggtgtggg tgacatcaga agggtgccac atcagtcccc   1920
tccccaacct cagtgactga cagaggatcc ggatctcaga gcctgagacc aggtttattg   1980
gggcctggcc tgtcctctaa gtcaagttta ggaaaacaag gataagattc tgtcataggc   2040
atagagagtt gcacataaaa aataccgaag aaaacccaaa attcaatcaa caattctgtc   2100
ttattgaaga gttgctagga ttcagagtaa aactcaaagg attcagtttg agcctagaat   2160
gatggttaga cttgtagtca ctgggctttt gttttgcttt atggaaatca ttgaaggtct   2220
ggatcccttt ctctgaatgg agagattgag agggatgtcg ggcagttccc attagattta   2280
gtggccttca tgttattcag aattgttttg ggtgatacct cacccctgtt aatcccagca   2340
ctttggggtg gggtgargsc aggcggatcc cttgaagcca gggactttca agaccagctt   2400
tnggcccaac atnggttgaa acctcc                                        2426

<210> 1356
<211> 1901
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (16)
<223> n equals a,t,g, or c

<400> 1356
aatgattcgn tttctntagg gaccacccaa ttaaatcttg tatcaagtat ttgtggaaaa     60
ctggaaatgt ttctctggta tggttggtga atgatgattt ggaggaggta ttaaagttta    120
tccgatccag ctttggcctg gtgttccacg tagaaaagga tgtaggcctt cgccttcacc    180
acagtctcct cgtcagtcag tgttacagta ctgtcattga agtggaacca gcggccttcg    240
tgagttgcgt atgctgtgta atgtccagaa ccaaccccgg aaccatggtg caccaccaca    300
gcggcgaggt catacaggca gctctccggg ccactgttct caggctctag taagtagcat    360
ttcatgtcta ggcctctcag tggaaattct acgtatgtat caactttatt tcttaaatat    420
gctgtccaat gaaatctttt caaatgtaag catagcacct tgggtagttt ttgaatccaa    480
aacttttttg tggacttttg tttctttttg catttatggc acatatataa ctctgtctca    540
tcaagttctt ctaagtcggt aaaactgcga agacaatctc gtaacgaaca aactggtcca    600
ttttcttgat tcttagagcg cttacttctg aactgacttg gaatatctaa tgaaaggtct    660
aggaatggat caaactttct agattctgtc ccacatatga ggcagttaac ctcattttgg    720
agaatgcctc cgaatatagc cgtgacaaca gtagatgctc catttatgca acacttgtta    780
cttgcagaca gagtagaatt ctcctgcaga attgctgagc gggaaacacc gttgaaaccg    840
ccctgaagtt ccaagtgtag gtggtccaaa aggtagcgca tgaattcatg ggcgtcctgc    900
tgttgatagc ccctaaagtt tggcataatc ttccaaacaa cataaaataa ggactctggg    960
ctaaatgcag tctggctgcc ttgccataaa gcacagagtg tctttctaaa ctcttctacc   1020
aaagacacat tgttatcccc ttggctcctg gtgtggtatg tccgccttcc tgctgttttc   1080
ccattcctta actccacggc gggcagttct ttgaaataac agcaaaactg ctcaatgtta   1140
ctgagtgact gaaggatggc attcatgaaa catgtgttcc ccaaattccg aaggcctgtg   1200
gcacaaatgg cagtggtgct tccatttact tttaataact tgctgtttag tgttgagttt   1260
tccaaaagtt ttcttttctt atgcctgtca gctgtgaaag ctgagttttc caagttctgt   1320
aagtgttctc tgactttctg taccagtccc agcttggtgt cattaaccac aaaatcatca   1380
cagcgataac agtatgtact gtagctactg caatccatac atactgtgtg ctgaacttta   1440
tcttgctttt ctgatttctt atggttggtt aaaggtactt gtgcatcttc ataatgtttt   1500
tttgcatggc cattcacata cctctcaaaa tctaggagag gaatctgtct cttcaactgc   1560
agaatttaag tgcttctact tttcttcttt tttaaaaaaa agttatctgt acaaagtatt   1620
ttcaggttcc ccaaatcctt ccacagtgga cacttgaaca agtcaaacag acccaagggc   1680
ttttgttgga ccggcacacg ctgcagcacc aggacgacgg ggagccgttg gggaacttgg   1740
ctgagtccgg agcaatgcag acgctggagc tcaggtgtgg acactccatg gccacgagga   1800
gggcagctgg gaggactgcg gctccaggac ccggcgaggt gggggcggag gaactccgga   1860
ggctccgtct ggtgtcgctt ctagccgggc gctcggccga g                       1901

<210> 1357
<211> 913
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (865)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (891)
<223> n equals a,t,g, or c

<400> 1357
agagcctact ggctcagtct caaatcgaaa tatggaaagg gcagagtcac ggagtggaag     60
aggaggttct ggtggtggta gtagttctgg ttccagttcg agttccagtt ccagttcgag    120
ttccagttcc agttcaagtt ccagttccag tcctagttcc agttccggtg gtgaaagttc    180
agaaactagc tcagatttat ttgaaggcag taatgaagga agctcatcat caggctcatc    240
aggtgccagg cgagagggtc gacatagggc cccagtcaca tttgatgaaa gtggctcttt    300
gcccttcctt agcctggctc agtttttcct ctttaaatga ggatgatgat gaccaaccta    360
ggaggactca ccaaagaaca gatttgacaa cttgggcaat gagaagtttt ggtgaaaatg    420
atgcattaaa aacctgtagt gtttgcatta cagaatatca gaaggcaaca aacttcgtaa    480
actaccttgt tcccatgagt accatgtcca ctgcatcgat cgctggttat ctgagaattc    540
tacctgtcct atttgtcgca ragcagtctt agcttctggt aacagagaaa gtgttgtgta    600
attaagatct gaactctyag ctatgtagct gatatagtga tgggcaaaca ggaatcactt    660
gcttttatgt ccactttttg agtggtactt aaatgtaaag taacaacctg aattgagtca    720
ttgctttctg aaggaatcat tgtcctttct ccagtttttg ttccagaata aaaggaaata    780
ttttaaaagc cacgttatag gacctaaaaa ctgatttccg tacccagtta aattgggagc    840
atccactgtt actgatattt accanataca cttgccaatt ttccctttgg naaccttaaa    900
agacctgcct tag                                                       913

<210> 1358
<211> 1249
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1241)
<223> n equals a,t,g, or c

<400> 1358
gtcgacccac gcgtccgctg taacccgcac acgaatttca cggtgcccac ggtttgggga     60
agcaccgtgc aagtctcttg gttggccctc atccaacgcg gcgggggctg caccttcgca    120
gacaagatcc atctggctta tgagagaggg gcgtctggag ccgtcatctt taacttcccc    180
gggacccgca atgaggtcat ccccatgtct cacccgggtg cagtagacat tgttgcaatc    240
atgatcggca atctgaaagg cacaaaaatt ctgcaatcta ttcaaagagg catacaagtg    300
acaatggtca tagaagtagg gaaaaaacat ggcccttggg tgaatcacta ttcaattttt    360
ttcgtttctg tgtccttttt tattattacg gcggcaactg tgggctattt tatcttttat    420
tctgctcgaa ggctacggaa tgcaagagct caaagcagga agcanaggca attaaaggca    480
gatgctaaaa aagctattgg aaggcttcaa ctacgcacac tgaaacaagg agacaaggka    540
aattggccct gatggagata gttgtgctgt gtgcattgaa ttgtataaac caaatgattt    600
ggtacgcatc ttaacgtgca accatatttt ccataagaca tgtgttgacc cmtggctgtt    660
agaacacagg acttgcccca tgtgcaaatg tgacatactc aaagctttgg gaattgaggt    720
ggatgttgaa gatggatcag tgtctttaca agtccctgta tccaatgaaa tatctaatag    780
tgcctcctcc catgaagagg ataatcgcag cgagaccgca tcatctggat atgcttcagt    840
acagggaaca gatgaaccgc ctctggagga acacgtgcag tcaacaaatg aaagtctaca    900
gctggtaaac catgaagcaa attctgtggc agtggatgtt attcctcatg ttgacaaccc    960
aacctttgaa gaagacgaaa ctcctaatca agagactgct gttcgagaaa ttaaatctta   1020
aaatctgtgt aaatagaaaa cttgaaccat tagtaataac agaactgcca atcagggcct   1080
agtttctatt aataaattgg ataaatttaa taaaataaga gtgatactga aagtgctcag   1140
atgactaata ttatgctata gttaaatggc ttaaaatatt taacctgtta acttttttcc   1200
acaaactcat tataatattt ttcataggca atttcctctc ngtagtgat               1249

<210> 1359
<211> 2826
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2817)
<223> n equals a,t,g, or c

<400> 1359
cagtcttcca gggcggcggt gggtgtccgc ttctctctgc tcttcgactg caccgcactc     60
gcgcgtgacc ctgactcccc ctagtcagct cagcggtgct gccatggcgt ggcggcggcg    120
cgaagccrgc gtcggggctc gcggcgtgtt ggctctggcg ttgctcgccc tggccctgtg    180
cgtgcccggg gcccggggcc gggctctcga gtggttctcg gccgtggtaa acatcgagta    240
cgtggacccg cagaccaacc tgacggtgtg gagcgtctcg gagagtggcc gcttcggcga    300
cagctcgccc aaggagggcg cgcatggcct ggtgggcgtc ccgtgggcgc ccggcggaga    360
cctcgagggc tgcgcgcccg acacgcgctt cttcgtgccc gagcccggcg gccgaggggc    420
cgcgccctgg gtcgccctgg tggctcgtgg gggctgcacc ttcaaggaca aggtgctggt    480
ggcggcgcgg aggaacgcct cggccgtcgt cctctacaat gaggagcgct acgggaacat    540
caccttgccc atgtctcacg cgggaacagg aaatatagtg gtcattatga ttagctatcc    600
aaaaggaaga gaaattttgg agctggtgca aaaaggaatt ccagtaacga tgaccatagg    660
ggttggcacc cggcatgtac aggagttcat cagcggtcag tctgtggtgt ttgtggccat    720
tgccttcatc accatgatga ttatctcgtt agcctggyta atattttact atatacagcg    780
tttcctatat actggctctc agattggaag tcagagccat agaaaagaaa ctaagaaagt    840
tattggccag cttctacttc atactgtaaa gcatggagaa aagggaattg atgttgatgc    900
tgaaaattgt gcagtgtgta ttgaaaattt caaagtaaag gatattatta gaattctgcc    960
atgcaagcat atttttcata gaatatgcat tgacccatgg cttttggatc accgaacatg   1020
tccaatgtgt aaacttgatg tcatcaaagc cctaggatat tggggagagc ctggggatgt   1080
acaggagatg cctgctccag aatctcctcc tggaagggat ccagctgcaa atttgagtct   1140
agctttacca gatgatgacg gaagtgatga gagcagtcca ccatcagcct cccctgctga   1200
atctgagcca cagtgtgatc ccagctttaa aggagatgca ggagaaaata cggcattgct   1260
agaagccggc aggagtgact ctcggcatgg aggacccatc tcctagcaca cgtgcccact   1320
gaagtggcac caacagaagt ttggcttgaa ctaaaggaca ttttattttt tttactttag   1380
cacataattt gtatatttga aaataatgta tattatttta cctattagat tctgatttga   1440
tatacaaagg actaagatat tttcttcttg aagagacttt tcgattagtc ctcatatatt   1500
tatctactaa aatagagtgt ttaccatgaa cagtgtgttg cttcagacta ttacaaagac   1560
aactggggca ggtactctaa tataaaggac aggtggtgtt tctaaataat tggctgctat   1620
ggttctgtaa aaaccagtta attctatttt tcaaggtttt tggcaaagca catcaatgtt   1680
agactagttg aagtggaatt gtataattca attcgataat tgatctcatg ggctttccct   1740
ggaggaaagg ttttttttgt tgtttttttt ttaagaactt gaaacttgta aactgagatg   1800
tctgtagctt ttttgcccat ctgtagtgta tgtgaagatt tcaaaacctg agagcacttt   1860
ttctttgttt agaattatga gaaaggcact agatgacttt aggatttgca tttttccctt   1920
tattgcctca tttcttgtga cgccttgttg gggagggaaa tctgtttatt ttttcctaca   1980
aataaaaagc taagattcta tatcgcacat gagcattaag ttcttcattg ccttgttaag   2040
gaaaatgagt aggcagactc agaatctgtt atattgattt cagttacaat ttaatcttta   2100
caattaaaag ggcgaaagat gtagaatttt agtttttgtt gttgactcga aataaccagt   2160
tttcttgatt agagtttaag cagatttaat accatgacct tgcttaaccg tttcttcttt   2220
tttacttgct tgctgttctt ttgggtcaaa ggagcaggct aatgcaaagc ttttggagac   2280
tgctaagtgt taaaaagtga ttaaacacac actctgctat tttttcactt cttggaggta   2340
gaagtcgagt atgaggcagt tattttttag agtgtggaat tatagtcttt ccttgctcct   2400
agttattctg tatatctyta ctttgtaggt aaaaataaat gtttatttaa macaattttt   2460
aaaattataa wtttattttt atagccatat gtaggatata aagatttata tagattattt   2520
tctcaagcta cttaatgctt taattctagc tactcatcat gaaatagtaa acagttttac   2580
tgaaataaac tctacagaca gatgcagtat gaggagctat tgaagtagaa aatgtatttc   2640
gctttgcaca ctgagttggt tttagcagac aacctcaagt aggtttccat aacagccatt   2700
acctttgaaa tctaccttct gtagtttatt ataaatagga aaatacatcc tgattctgta   2760
gcaagtagat tgtttgctct ttgtctttaa gaaatactas gagggccggg cgcggtnggg   2820
gggccc                                                              2826

<210> 1360
<211> 1515
<212> DNA
<213> Homo sapiens

<400> 1360
gcccacgcgt ccggccggag ggacgatgag ctgcgcgggg cgggcgggcc ctgcccggct     60
cgccgcgcta gccctgctga cctgcagcct gtggccggca cgggcagaca acgcgagcca    120
ggagtactac acrgcgctca tcaacgtgac ggtgcaggag cccggccgcg gcgccccgct    180
cacgtttcgc atcgaccgcg ggcgctacgg gcttgactcc cccaaggccg aggtccgcgg    240
ccaggtgctg gcgccgctgc ccctccacgg agttgctgat catctgggct gtgatccaca    300
aacccggttc tttgtccctc ctaatatcaa acagtggatt gccttgctgc agaggggaaa    360
ctgcacgttt aaagagaaaa tatcacgggc cgctttccac aatgcagttg ctgtagtcat    420
ctacaataat aaatccaaag aggagccagt taccatgact catccaggca ctggagatat    480
tattgctgtc atgataacag aattgagggg taaggatatt ttgagttatc tggagaaaaa    540
catctctgta caaatgacaa tagctgttgg aactcgaatg ccaccgaaga acttcagccg    600
tggctctcta gtcttcgtgt caatatcctt tattgttttg atgattattt cttcagcatg    660
gctcatattc tacttcattc agaagatcag gtacacaaat gcacgcgaca ggaaccagcg    720
tcgtctcgga gatgcagcca agaaagccat cagtaaattg acaaccagga cagtaaagaa    780
gggtgacaag gaaactgacc cagactttga tcattgtgca gtctgcatag agagctataa    840
gcagaatgat gtcgtccgaa ttctcccctg caagcatgtt ttccacaaat cctgcgtgga    900
tccctggctt agtgaacatt gtacctgtcc tatgtgcaaa cttaatatat tgaaggccct    960
gggaattgtg ccgaatttgc catgtactga taacgtagca ttcgatatgg aaaggctcac   1020
cagaacccaa gctgttaacc gaagatcagc cctcggcgac ctcgccggcg acaactccct   1080
tggccttgag ccacttcgaa cttcggggat ctcacctctt cctcaggatg gggagctcac   1140
tccgagaaca ggagaaatca acattgcagt aacaaaagaa tggtttatta ttgccagttt   1200
tggcctcctc agtgccctca cactctgcta catgatcatc agagccacag ctagcttgaa   1260
tgctaatgag gtagaatggt tttgaagaag aaaaaacctg ctttctgact gattttgcct   1320
tgaaggaaaa aagaacctat ttttgtgcat catttaccaa tcatgccaca caagcattta   1380
tttttagtac attttatttt ttcataaaat tgctaatgcc aaagctttgt attaaaagaa   1440
ataaataata aaataaaaaa aaaaaaaaaa cycgaggggg ggcccgtacc caattcgccc   1500
tatagtgagc gattc                                                    1515

<210> 1361
<211> 2447
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (961)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (964)
<223> n equals a,t,g, or c

<400> 1361
gctgattctc tggctgtgtg gggcgcacgg tcccgggata ctggggacgg cggggtggga     60
gggcgccgtc tggggccgcg cgcgggcggg ggagatggcg gcgcgatgga gcagcgaaaa    120
cgtggttgta gagttccgtg actcccaggc aactgcgatg tctgtggact gtcttgggca    180
gcatgcagtg ctttctggcc gcakattctt atacatcgtc aatctagatg cccctttcag    240
aaggtcaccg aaagatctct cgccagagca aatgggacat tggagctgtg cagtggaatc    300
ctcatgacag ctttgcacac tattttgcgg cttcgagtaa ccaacgagta gacctttaca    360
agtggaaaga cggcagtggg gaagttggca caacctttac aaggccacac tcgtgtcatc    420
agcgacttgg acttgggcgg tgtttgagcc tgacctcctg gttaccagct ctgtggacac    480
ctacatctac atttgggata tcaaagacac aaggaaacct actgttgcac tgtctgctgt    540
tgcgggtgcc tcccaggtca aatggaataa aaaaaatgct aactgccttg ccaccagcca    600
tgacggcgat gtgcggatat gggataagag gaaacccagt acagcagtgg aatatctagc    660
cgcccacctc tccaaaatcc atggcctgga ctggcaccca gacagcgagc acattcttgc    720
tacctccagt caagacaatt ctgtgaagtt ctgggattac cgccagcctc ggaaatacct    780
caatattctt ccttgccagg tgcctgtytg gaaggccaga tacacacctt tcagcaatgg    840
attggtgact gtgatggttc cccagctgcg gagggaaaac agccttctcc tgtggaatgt    900
ctttgacttg aacaccccag tccacacctt cgtggggcat gatgatgtgg tcctggagtt    960
ncantggaag aaagcagaag gaagggtcca aggactatca actggtgacg tggtcccggg   1020
atcagacctt gagaatgtgg cgggtggatt cccagatgca gaggctttgt gcaaatgaca   1080
tattagatgg tgttgatgag ttcattgaga ktatttccct tctgccggaa cctgagaaga   1140
ccctgcacac tgaagataca gatcaccagc acactgcaag ccatggggag gaagaagccc   1200
taaaagaaga tccccctaga aatctcctgg aagagaggaa atcagatcaa ctggggctgc   1260
ctcagacctt gcagcaggaa ttctccctga tcaatgtgca aatccggaat gtcaatgtgg   1320
agatggatgc ggcagacagg agctgcacag tgtctgtgca ctgcagcaac catcgtgtca   1380
agatgctggt gaagttccct gcacagtacc caaacaacgc cgccccttcc ttccagttta   1440
ttaaccccac aaccatcaca tccaccatga aagctaagct gctgaaggtg ggggtctggg   1500
ttcccaaatt ctccttgctg ttctgcatca ttgtctagat ggattagtaa agaagaatga   1560
aaactccagt agatgagatt cggaagtcat ctgtttcgta cacacactag tattagcaac   1620
gtaacctctg aacttgccat ttactttgtg cagaaaacat cagagcagtg gttcttaacc   1680
ttttttgggt catagacttc ctttgaattc taatgaaaat tatggaccct tcctcagaaa   1740
aatctgcaca atgattgcat atgatttgag aaatattgcc tgtaaatatg tgaattgcat   1800
agaatctgcc cacagatctc attaatacta tgcattcatc tccggttagg agatttgcaa   1860
tccaatttca tttagcagcc caggttagga gccctgcagt ccaatttcat ttacctgaaa   1920
acaacaagca agatgtattc tgaagctaaa agatatttta taattagaaa aaaacatatg   1980
taaggtcata aaaaaaattt tatcccatag aaggagctgg tgttatccta gagacaggct   2040
ggctagctgc acagtaggtg tccaggtgga ggcaccacag cctggcatct gtgtttaatt   2100
ctgcagattc agagatttaa tgcatcagtt catccagagc aaatcaggtg gaatctccat   2160
gacaaagccc catgagcctc ttcataccsg ttcagtctga gcagtgtcac aagtgaaggg   2220
actgaagtat tctgacaaac tcaggccaag ctgaatgttg ctcatttttt gtccagtttr   2280
ggtcgtggac acttgattgt tccaccttgt tgggggtatc acatggaacc aggaaatttt   2340
caagtggctt aaggatctct gaaatgccag taactcagat cttgtggtat ttgacatgtt   2400
aaacttggaa tctgaatatg ccgttgccta gtttggacat acaaaaa                 2447

<210> 1362
<211> 978
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (496)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (975)
<223> n equals a,t,g, or c

<400> 1362
tgacaaaggg tggcttcagg atctgattga gaaagttgtc atcctgcgaa aagctgtgca     60
actcactcaa gccatggaca ctagtactgt aggagttctc ttggctgcga agatgagtca    120
gtatgccaat ttgttggcag ctcagggcag tattgctgca gccttggctt ttcttcctga    180
caacaccaac cagccaaata tcatgcagct tcgtgacaga ctttgtagag cacaaggaga    240
gcctgtagca ggacatgaat cacctaaaat tccgtacgag aaacagcagc tccccaaggg    300
caggcctgga ccagttgctg gccaccacca gatgccaaga gttcaaactc aacaatatta    360
tccccatgga gaaaatcctc cacctccggg tttcataatg catggaaatg ttaatccaaa    420
tgctgctggt cagcttccca catctccagg tcatatgcac acccaggtac caccttatcc    480
acaggccama gccttnatca accagcccag ccgtatccct tcggaamagg ggggtcagca    540
atgtatcgac ctcagcagcc tgttgctcct cctacttcaa asgcttaccc taacacccct    600
tacatatctt ctgcttcttc ctatactggg cagtctcagc tgtacgcagc acagcaccag    660
gcctcttcac ctacctccag ccctgctact tctttccctc ctcccccttc ctctggagca    720
tccttccagc atggcggacc aggagctcca ccatcatctt cagcttatgc actgsctyct    780
ggaacmacag gtacactgcc tgctgccagt gagctgcctg cgtcccaaag aacaggtctg    840
cgcttgaaag ggatttggtt tggccccctc ctttatttgt ttatgaacag atgggtggat    900
ggaggggtat tatttctaac tgtttgtaaa ctgggtaatg tgaggtgttg actgaggttt    960
gggtttggtt tttgngtt                                                  978

<210> 1363
<211> 1092
<212> DNA
<213> Homo sapiens

<400> 1363
cttttctgac gtgcctgagc atgtccacat tagaatctgt gacataccta cctgaaaaag     60
gtttatattg tcagagactg ccaagcagcc ggacacacgg gggcacagaa tcactgaagg    120
ggaaaaatac agaaaatatg ggtttctacg gcacattaaa aatgattttt tacaaaatga    180
aaagaaagtt ggaccatggt tctgaggtcc gctctttttc tttgggaaag aaaccatgca    240
aagtctcaga atatacaagt accactgggc ttgtaccatg ttcagcaaca ccaacaactt    300
ttggggacct cagagcagcc aatggccaag ggcaacaacg acgccgaatt acatctgtcc    360
agccacctac argcctccag gaatggctaa aaatgtttca gagctggagt ggaccagaga    420
aattgcttgc tttagatgaa ctcattgata gttgtgaacc aacacaagta aaacatatga    480
tgcaagtgat agaaccccag tttcaacgag acttcatttc attgctccct aaagagttgg    540
cactctatgt gctttcattc ctggaaccca aagacctgct acaagcagct cagacatgtc    600
gctactggag aattttggct gaagacaacc ttctctggag agagaaatgc aaagaagagg    660
ggattgatga accattgcac atcaagagaa gaaaagtaat aaaaccaggt ttcatacaca    720
gtccatggaa aagtgcatac atcagacagc acagaattga tactaactgg aggcgaggag    780
aactcaaatc tcctaaggtg ctgaaaggac atgatgatca tgtgatcaca tgcttacagt    840
tttgtggtaa ccgaatagtt agtggttctg atgacaacac tttaaaagtt tggtcagcag    900
tcacaggcma atgtctgaga acattagtgg gacatacagg tggagtatgg tcatcacaaa    960
tgagagacaa catcatcatt agtggatcta cagatcggac actcaaagtg tggaatgcag   1020
agactggaga atgtatacac accttatatg ggcatacttc cactgtgcgt tgtatgcatc   1080
ttcatgaaaa aa                                                       1092

<210> 1364
<211> 546
<212> DNA
<213> Homo sapiens

<400> 1364
ctgacaacaa gatggaattt gcacaaatca gtcgtgttaa gacatttcag gagaaccttt     60
cagcatttaa acgtgatccc caaatcaata ttttgctgct gcccctgcac acaggttcta    120
atggattaac tatcattgaa gcaactcatg ttctcttggt ggagcccata ttgaaccctg    180
cccatgagct tcaggccata gggagggtgc accgaattgg acagacaaaa cctactattg    240
tacacagatt cttaattaaa gcaacaatag aagaaagaat gcaggcaatg ctgaaaactg    300
ctgagagaag gttttttgag gaacaggcgt tattttgttt tcatgacatc accccattct    360
cccacccctg gtccctgaca actgccattc tacagttgag agatttggtg atttgtgagt    420
tgttttttat ttactttaaa aattttttga tttgtttttt atcatctttt tcaatttaga    480
gatgttttgc acaagtaaaa attatggggc ttattcagta atacatgtct gtaaggaata    540
aacatt                                                               546

<210> 1365
<211> 1804
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1785)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1804)
<223> n equals a,t,g, or c

<400> 1365
ggcgctcacc gcctcaggtc cagcctttcc tgccaaggtg gctggctgag cctaactgtg     60
tcagaaggaa tgtcaccgaa gacctggttc ctatcgagga catccctgac gtccatcctg    120
acctgcagaa gcagctgcgg gcacacggca tctcgtccta ctttccagtc caggcagctg    180
tgattcctgc cctcctggag agcgcagctg tgggtttctg gtgggcagag gtggctaccg    240
gcctagcgac ctctgtgttt ctgccccaac aggcagtggg aagacactgg ccttcgtcat    300
ccctgtggtg caggccctgc tttcgagagt ggtctgccac atccgtgccc tggttgtgct    360
gcccaccaag gagctggccc rgcaggtgag caaagttttc aacatctaca cagatgccac    420
acctctgaga gtctccctgg ttacgggaca gaagtctctg gccaaggagc aggagagcct    480
cgtccagaaa acagctgatg ggtaccgctg cttggctgac atcgtggtag ccacccccgg    540
ccgcctggtg gaccacatcg accagacccc aggattcagc ctccagcagc tccgcttcct    600
gattatcgac gaggctgacc ggatgattga cagcatgcat cagtcctggc tgccgcgggt    660
ggtggcgrcc gccttccaga gcgaggaccc cgcggacccc tgtgccctgc tccagcgaag    720
gcaggcccag gctgtgacag ccgccagcac ctgctgtccc cagatgcccc tgcagaagct    780
gctcttctca gctactctga cccagaaccc tgaaaagctg cagcagctgg gcctccacca    840
gccccggctt ttctccacag ggctagcaca caggggcctg gaagatacag atggggacgg    900
ggattcgggg aagtatgcct ttcctgttgg gctcacgcac cactacgtgc cctgcagcct    960
cagctctaag ccgctggtcg tcctgcacct ggtcctggag atgggcttct cgagggttct   1020
ctgcttcact aactcccgag agaactccca caggctcttc ctgctggtgc aagcttttgg   1080
gggtgtggac gtggctgagt tctcctcgcg ctacgggcct ggccagagga ggatgatcct   1140
gaagcagttt gaacagggga agatccagct gctcatcagc acggacgcca ccgcgcgagg   1200
catcgacgtg cagggtgtgg agctggtggt gaactacgac gccccccagt acctgagaac   1260
ctacgtgcac cgggttggga ggacagctcg cgctgggaaa actggacagg ccttcacact   1320
gctcctgaaa gtgcaggaga ggagattcct ccgaatgcta actgaagctg gggcacctga   1380
gttgcagcgg cacgagctct ccagcaagct gctgcagccg ctggttcctc ggtacgagga   1440
ggccctgtcc cagctggagg agtctgtcaa ggaagagcgc aagcagaggg cggcctaggc   1500
tggggctcag agggccggag ggactgaacg ctcaccaccc tgaccctcct tccagagcag   1560
tgctgatcac tggatcctgt atgtgaggaa aggaatcccc cagtggacac agccttcctc   1620
cccaagcacg tggtctctgc gccaggcagc ccgggcgtca gagctcaagc acctgccccg   1680
actggagact tcagggcttg tcactttcag agtgtggagg tcaggatggc tgcgggcaat   1740
gaagccttag taaaacggtg aaaagtactc ccagaaaaaa aaaantgaac tataataaaa   1800
ggan                                                                1804

<210> 1366
<211> 2539
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (155)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (511)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1257)
<223> n equals a,t,g, or c

<400> 1366
ncctgctgct gaatagggtg ggttcacggt aaccctgctc ggcaacggcg cgcaggatat     60
cagggcttaa acccaaagaa tcgaaagacm taactactcc gaaccgcccc gaccgttacc    120
ggtgtagttt tcagggagat tactgaaaag gaaantgaca aaaaccacaa tgtcatgagg    180
gagcggagtg tagcagtttt tgtgacgcag cgcataaatt atccctgtga ctggcgttgc    240
taaaattctt agccatactg gacaactccc ctatggagtc ataatcttaa tcaatcattt    300
gattaagaat ggactgtgcg atgaataatc ctgccatgac aatcaagggt gaacaggcga    360
aaaaacagct gattgctgcc gcactggcgc agtttggtga atatggaatg aacgccacca    420
ctcgcgagat agccgcccag gccgggcaga atatcgctgc catcacctac tacttcggtt    480
cgaaagaaga tttgtacctc gcctgcgccc nagtggattg ccgattttat tggcgagcag    540
ttccgtccgc atgccgagga agccgaacgc ttgttcgcgc aaccacagcc tgatcgggct    600
gccatccgtg aactgatcct tcgcgcctgc aggaacatga ttaagctgct cacccaggat    660
gacaccgtca acctcagcaa gtttatctcc cgtgagcagc tctctcccac ggcagcctac    720
cacctggtgc acgaacaggt gattagtccg ctacacagcc acctgacacg cctgattgcc    780
gcctggaccg gctgcgacgc caatgacacc cgcatgatcc ttcataccca tgcgttgatt    840
ggtgagattc tggcgttccg tcttggcaaa gaaacaattc tgttacgtac cggctggacc    900
gcgttcgatg aagaaaagac cgaactgatc aaccagacgg tgacctgtca tatcgacctg    960
attttgcaag gattatcgca aaggagtttg tagtgatgaa aaaacctgtc gtgatcggat   1020
tggcggtagt ggtacttgcc gccgtggttg ccggaggcta ctggtggtat caaagccgcc   1080
aggataacgg cctgacgctg tatggcaacg tggatattcg tacggtaaat cttagtttcc   1140
gtgttggggg gcgcgttgaa tcgctggcgg tggacgaagg tgatgctatc aaagcgggcc   1200
aggtgctggg cgaactggat cacaagccgt atgagattgc cctgatgcag gcgaaancgg   1260
gtgtttcggt ggcacaggcg cagtatgacc tgatgcttgc cgggtatcgc aatgaagaaa   1320
tcgctcaggc cgccgcagcg ktgaaacagg cgcaagccgc ctatgactat gcgcagaact   1380
tctataaccg ccagcaaggg ttgaaacakg acatacgttc aargattaac cccgwwtgaa   1440
ggttagcttg ttagttacat ttagtaacac atatctggct acttaatccc cattctgccc   1500
ccgcggttac gctttcttat ctattctttc aatcagcact tcacccaatt catccttaat   1560
tctaataact ggctattgcg ccttacctcg tgttttgtct ttttttcatt accaatgtgt   1620
gcatgtgagg aacaatatgg cactgcaaaa tgagaaaaat agtcgttatc ttttgcgcga   1680
ctggaaacca gaaaatccgg ccttctggga aaataaagga aaacatattg ctcgaagaaa   1740
tctctggata tcagtcagtt gtctacttct tgccttctgt gtctggatgc watttagcgc   1800
agttaccgyt aatctcaata aaatcggttt taattttact accgatcaac tctttttatt   1860
aaccgcatta ccctccgttt ctggcgcatt attgcgtgtt ccctactcct ttatggtgcc   1920
tatattcggt ggacgccgat ggacggtttt tagtactgca atcctgatta ttccttgcgt   1980
ctggctcgga attgccgtgc aaaatccgaa tactcctttt gggatattta tcgttatcgc   2040
tttgctatgc ggttttgcag gtgcaaactt tgcttcgagc atgggcaata tcagtttctt   2100
ctttccaaaa gccaaacaag ggagcgctct tgggattaat ggcggattag gaaacttagg   2160
tgtaagtgta atgcagctgg ttgcaccgct ggtcattttt gtacctgtat ttgcctttct   2220
cggcgtcaat ggcgtaccgc aggccgacgg ttcggtgatg tcgctggcga atgccgcatg   2280
gatttgggta ccgctactgg cgattgccac gatcgccgca tggtcaggga tgaatgatat   2340
cgccagttca cgcgcctcaa ttgccgacca gctccctgtc ttacaacgcc tgcatctctg   2400
gctgctgagc ctgctttacc ttgcccactt cggttcgttt atcggttttt ctgcgggttt   2460
tgccatgctg gcaaaaaccc agttcccgga tgtgaatatt ctgcgcctgg cgttctttgg   2520
cccatttatc ggtgccatc                                                2539

<210> 1367
<211> 1475
<212> DNA
<213> Homo sapiens

<400> 1367
gcaatcagac acccgggtgt gctgagctag cactcagtgg gggcggctac tgctcatgtg     60
attgtggagt agacagttgg aagaagtacc cagtccattt ggagagttaa aactgtgcct    120
aacagaggtg tcctctgact tttcttctgc aagctccatg ttttcacatc ttccctttga    180
ctgtgtcctg ctgctgctgc tgctactact tacaaggtcc tcagaagtgg aatacagagc    240
ggaggtcggt cagaatgcct atctgccctg cttctacacc ccagccgccc cagggaacct    300
cgtgcccgtc tgctggggca aaggagcctg tcctgtgttt gaatgtggca acgtggtgct    360
caggactgat gaaagggatg tgaattattg gacatccaga tactggctaa atggggattt    420
ccgcaaagga gatgtgtccc tgaccataga gaatgtgact ctagcagaca gtgggatcta    480
ctgctgccgg atccaaatcc caggcataat gaatgatgaa aaatttaacc tgaagttggt    540
catcaaacca gccaaggtca cccctgcacc gactctgcag agagacttca ctgcagcctt    600
tccaaggatg cttaccacca ggggacatgg cccagcagag acacagacac tggggagcct    660
ccctgatata aatctaacac aaatatccac attggccaat gagttacggg actctagatt    720
ggccaatgac ttacgggact ctggagcaac catcagaata ggcatctaca tcggagcakg    780
gatctgtgct gggctggctc tggctcttat cttcggcgct ttaattttca aatggtattc    840
tcatagcaaa gagaagatac agaatttaag cctcatctct ttggccaacc tccctccctc    900
aggattggca aatgcagtag cagagggaat tcgctcagaa gaaaacatct ataccattga    960
agagaacgta tatgaagtgg aggagcccaa tgagtattat tgctatgtca gcagcaggca   1020
gcaaccctca caacctttgg gttgtcgctt tgcaatgcca tagatccaac caccttattt   1080
ttgagcttgg tgttttgtct ttttcagaaa ctatgagctg tgtcacctga ctggttttgg   1140
aggttctgtc cactgctatg gagcagagtt ttcccatttt cagaagataa tgactcacat   1200
gggaattgaa ctgggacctg cactgaactt aaacaggcat gtcattgcct ctgyatttaa   1260
gccaacagag ttacccaacc cagagactgt taatcatgga tgttagagct caaacgggct   1320
tttatataca ctaggaattc ttgacgtggg gtctctggag ctccaggaaa ttcgggcaca   1380
tcatatgtcc atgaaacttc agataaacta gggaaaactg ggtgctgagg tgaaagcata   1440
acttttttgg cacagaaagt ctaaaggggc cactg                              1475

<210> 1368
<211> 1732
<212> DNA
<213> Homo sapiens

<400> 1368
agctatttag gtgacactat agaaggtacg cctgcaggta ccggtccgga attcccgggt     60
cgacccacgc gtccggttgt ccaaaaagct ttctgaggta tagttacttt tagaagagga    120
aataccgttt taattcattt gtgctcttga gattgtgtat gtgtggtagg tgtttttgtt    180
gtattattac aggttgatga aaagcccaga accttgatga cagattgtct ggttataaag    240
cattttttac gtaaaatcat catggtgcac cctaaggtca gatttcattt cagtgtaaag    300
gtaaatggaa tcctctccac agagatcttt ggggtggaga atgaacccac tttgaacctt    360
gggaatggaa ttgctctttt ggtcgactcc cagcattatg tgagtagacc aaattttggt    420
acaattgaat cacactgcag cagaattcac cctgtgctag gacatccagt aatgcttttc    480
atccctgaag acgtggctgg catggacttg ktgggagaac tgatactgac tycagcagct    540
gcactgtgcc ccarcccaaa ggtttcttcc aaccagctta acaggatttc ttcagtttcc    600
atatttctat atggaccttt gggtctgcct ctgatattgt caacttggga gcagccgatg    660
actactttct tcaaagatac ctcttcttta gttgactgga aaaaatacca tttgtgtatg    720
atacccaatt tggatctcaa tttggataga gatttggtgc ttccagatgt gagttatcag    780
gtggaatcca gtgaggagga tcagtctcag actatggatc ctcaaggaca aactctgctg    840
ctttttctct ttgtggattt ccacagtgca tttccagtcc agcaaatgga aatctgggga    900
gtctatactt tgctcacaac tcatctcaat gccatccttg tggagagcca cagtgtagtg    960
caaggttcca tccaattcac tgtggacaag gtcttggagc aacatcacca ggctgccaag   1020
gctcagcaga aactacaggc ctcactctca gtggctgtga actccatcat gagtattctg   1080
actggaagca ctaggagcag cttccgaaag atgtgtctcc agacccttca agcagctgac   1140
acacaagagt tcaggaccaa actgcacaaa gtatttcgtg agatcaccca acaccaattt   1200
cttcaccact gctcatgtga ggtgaagcag cgctaaccct agaaaaaaag gactcagccc   1260
agggcactga ggacgcacct gataacagca gcctggagct cctagcagat accagcgggc   1320
aagcagaaaa caagaggctc aagaggggca gcccccgcat agaggagatg cgagctctgc   1380
gctctgccag ggccccgagc ccgtcagagg ccgccccgcg ccgcccggaa gccaccgcgg   1440
cccccctcac tcctagagga agggagcacc gcgaggctca cggcagggcc ctggcgccgg   1500
gcagggcgag cctcggaagc cgcctggagg acgtgctgtg gctgcaggag gtctccaacc   1560
tgtcagagtg gctgagtccc agccctgggc cctgagccgg gtccccttcc gcaagcgccc   1620
accgatccgg aggctgcggg cagccgttat cccgtggttt aataaagctg ccgcgcgctc   1680
accaaaaaaa aaaaaaaaaa aaaaaccggc acgagggggg gcccgtaccc aa           1732

<210> 1369
<211> 1593
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (524)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (654)
<223> n equals a,t,g, or c

<400> 1369
gcgcgacggt gcggttggcg gacccggkct ggcttgtggg gaaacgaaac tgagggagga     60
ggcggcggct ctggcagcgg cggcgacagt gtcggcctga ccccccctcc gctccccggc    120
agctcgctct ctcccctcag cttaacgatg aagaggagaa ctgacccaga atgcactgcc    180
cccatcaaga aacagaaaaa aagagttgca gagcttgccc tgagcctcag ctccacgtcc    240
gatgatgaac ctccctcctc tgtcagtcat ggagcaaaag catctactac aagccttagt    300
gggtctgata gtgagaccga ggggaaacaa cacagctctg actcttttga cgatgcattc    360
aaagcagact ctcttgtgga aggaacttct tctcgctatt ccatgtataa tagcgtctcc    420
cagaagctta tggccaagat gggcttcagg gaaggtgaag gattgggtaa atacagccag    480
ggtcggaagg acatcgttga ggcttccagt cagaaaggtc gaanaggctt gggtctgaca    540
ctccggggct ttgaccagga gctgaacgtg gactggcgag atgagccaga rcccagtgct    600
tgtgarcarg tgtcatggkt tccagaatgk accactgaaa ttcctgacac tcangaaatg    660
agcgattgga tggtggtggg aaagagaaag atgattattg aagatgaaac agagttttgt    720
ggggaagagc tgcttcacag tgtgttgcag tgtaagagcg tgtttgatgt cttggatggg    780
gaagagatgc ggcgagctcg gactcgggcc aatccctatg agatgatccg aggagtcttc    840
tttctaaaca gggcagcaat gaagatggct aacatggatt ttgtatttga tcgcatgttc    900
acaaatccgc gggactctta tgggaagcca ctggtgaagg accgggaagc tgagcttctg    960
tactttgctg atgtctgcgc aggcccaggt ggcttctcag agtatgtgct gtggaggaag   1020
aagtggcatg caaagggctt tggaatgact ttgaagggcc ctaatgactt caagctggag   1080
gacttctact ctgcttccag tgaactcttc gaaccctact atggtgaggg tgggattgat   1140
ggagatggag atatcacccg cccagagaac atctctgctt ttcggaattt tgtcctggat   1200
aacacagatc gcaagggtgt ccattttctg atggctgatg ggggtttctc ggtggagggg   1260
caggagaacc tgcaggagat cctcagcaag cagctgcttc tgtgtcagtt cctcatggcg   1320
ctgtccattg tccggacagg aggccacttc atctgtaaaa cctttgacct gttcacaccg   1380
tttagtgtgg ggcttgtcta cctgctgtac tgctgctttg aacgartttg tctcttcaag   1440
cctattacca gccgtcctgc caactcagag aggtatgtgg tgtgcaaggg cctgaaggtg   1500
ggcatagatg atgtkcggga ttacctcttc gcagtgaata tttaaactca atcagctgcg   1560
ggaacacggg attccgacgt caactttggt ggt                                1593

<210> 1370
<211> 2508
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2498)
<223> n equals a,t,g, or c

<400> 1370
ggacctgtgt gctgcaagga gctaaggcct tcagtgtccc cttccttacc caggtttctc     60
acagaatgga ttcccagcgg gaacttgcag aggaactgcg gctttaccaa tccacccttc    120
ttcaggatgg tctaaaagat ctcctggatg agaaaaaatt catcgattgc accctaaaag    180
caggtgacaa aagtcttcct tgccacagat tgattttgtc agcttgtagt ccttacttcc    240
gtgagtactt tttatctgaa attgatgagg cgaaaaaaaa ggaggtagtg ctagacaatg    300
tggatcctgc tatacttgat ttaatcatca aatacctgta ctctgccagt attgatctca    360
atgacggaaa tgtgcaagat atttttgcat tggccagccg ctttcagatc ccctcagtgt    420
ttactgtctg cgtttcttat cttcagaaaa gacttgctcc tggtaactgt ctagccatcc    480
taagattagg acttcttctt gactgcccga gactcgccat ttctgcccgt gaatttgtgt    540
ctgatcgctt tgtacagatt tgtaaggaag aggactttat gcaactgtct ccacaggaac    600
tgatctcagt catttcaaat gacagcctaa atgtagaaaa agaagaagca gtatttgagg    660
cagtgatgaa atgggtgcga acagacaagg aaaacagggt taaaaacctt agtgaagtgt    720
ttgattgtat ccgttttcgc cttatgacag aaaaatattt taaggatcat gttgagaaag    780
atgatataat taaaagcaac ccagacctcc agaaaaaaat caaagttcta aaagatgctt    840
tcgcaggcaa actcccagaa cctagcaaaa atgccgcgaa gactggggct ggtgaggtga    900
atggtgatgt tggtgatgaa gatttacttc ctggttacct gaatgacatt cccaggcatg    960
gaatgtttgt aaaagacctc atcctcttgg ttaatgacac agcagcagtg gcttatgacc   1020
ccacggaaaa tgaatgctac cttactgcac tggctgagca gattcccaga aatcattcca   1080
gcattgttac ccagcaaaat cagatatatg tggtaggagg actatatgtg gatgaagaaa   1140
ataaggatca acctctacag tcatacttct tccagctcga tagcatagca tctgaatggg   1200
ttggacttcc acctctgcct tcagccaggt gtctcttcgg tctgggagag gtggatgata   1260
aaatctatgt agttgcaggc aaagaccttc aaacagaggc ttcgctggat tcagtattat   1320
gctatgatcc tgtggctgca aaatggaacg aagtaaaaaa actccctatc aaagtctatg   1380
gccataatgt gatttcacat aaagggatga tatattgtct aggaggaaag acagatgaca   1440
aaaaatgtac aaacagggtg tttatcttca accccaaaaa aggagattgg aaagatctgg   1500
ctccaatgaa aattcctcgt tccatgtttg gagtagcagt ccataaaggc aaaattgtga   1560
ttgcaggagg tgtcactgaa gatggtcttt cagcttcagt tgaagctttt gaccttacaa   1620
caaataaatg ggatgtaatg accgaatttc cccaagaaag aagctccatc agtttggtca   1680
gcctggctgg atctctgtat gcaattggtg gttttgctat gattcaactg gagtctaaag   1740
aatttgcacc cactgaagtc aatgacatat ggaagtatga agatgataaa aaagaatggg   1800
ctgggatgtt gaaggaaata cgttatgctt caggagctag ttgcctagca acacgtttaa   1860
atctcttcaa actgtctaaa ctgtgaacaa ggtgacaaaa cataatagat tgggaggtgg   1920
tttgtttggt gaatggggct ttaatttatt ctgtttttta aaagcttgta cagacactca   1980
tgtagaaatt attcaagaag ttattgtcta agagatgagc agtaggtaag aaaacctcag   2040
tcattgactc ttcaatgtaa tgatcagagt ttaaaaccat tttctaataa taaattaaat   2100
cttcagttga acaaattatt ttgtgaatct gtttcactca atggattgta aagaaggctc   2160
ctaaatttga gttgtttgct aatcatttca tttgcatcat tagggtatcc ttaaactgat   2220
tttctattac aattggaagt ggagaatatg tgcatctaca ctaaaaaaat gtttaagata   2280
tcaaaaacct ctcctcgtgc ttcaaaatga caggaatcct gtgcattata ctaagaatta   2340
catgccataa gatgacttca gaaatcctac ttcagaagtg taataaatgg atggggaaat   2400
cgtttgatgg ggaaaagtct cttgtaagta aaagtagtca aattcaaaca aaaaaaaaaa   2460
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaanaa aaaaaaaa                2508

<210> 1371
<211> 2665
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (689)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2662)
<223> n equals a,t,g, or c

<400> 1371
gggaggcaca ggagcaaggg gagcaacaga gctggccagt ctgtgtgtgg tggggctgat     60
gcctgcctgc tcacccctgt cccctgtttt gccaactgtc aggccacagt tgtaagggat    120
cttgtggctg tcaggatggc agaggagcag gagttcaccc agctctgcaa gttgcctgca    180
cagccctcac acccacactg cgtgaacaac acctaccgca gcgcacagca ctcccaggct    240
ctgctccgag ggctgctggc tctccgggac agcggaatcc tcttcgatgt tgtgctggtg    300
gtggagggca gacacatcga ggcccatcgc atcctgctgg ctgcgtcctg cgattacttc    360
agaggaatgt ttgctggggg attgaaggag atggaacagg aagaggtcct gatccacggt    420
gtgtcctaca atgctatgtg ccaaatccta catttcatat acacctccga gctggagctc    480
agcctgagca atgtacaaga gacactggtg gctgcctgcc agcttcagat cccagaaatt    540
atccatttct gctgtgattt cctcatgtcc tgggtggacg aagagaacat tctcgatgtc    600
taccggctgg cagagctgtt tgacttgagc cgcctgactg agcaactgga cacctatatc    660
ctcaaaaact ttgtggcctt ctctcggant gacaagtacc gccagcttcc attggagaag    720
gtctactccc tcctcagcag caatcgcctg grggtctcct gcgagaccga ggtatatgag    780
ggggcccttc tctaccatta tagcctggag caggtgcagg ctgaccagat ctcgctgcac    840
gagcccccaa agctccttga gacagtgcgg tttccctgat ggaagctgag gtcctgcagc    900
ggctgcatga caagctggac cccagccctt tgagggacac agtggccagc gccctcatgt    960
accaccggaa cgagagccta cagcccagcc tgcagagccc gcaaacggag ctgcggtcgg   1020
acttccagtg cgttgtgggc ttcgggggca ttcactccac gccgtccact gtcctcagcg   1080
accaggccaa gtatctaaac cccttactgg gagagtggaa gcacttcact gcctccctgg   1140
ccccccgcat gtccaaccag ggcatcgcgg tgctcaacaa cttcgtatac ttgattggag   1200
gggacaacaa tgtccaagga tttcgagcag agtcccgatg ctggaggtat gacccacggc   1260
acaaccgctg gttccagatc cagtccctgc agcaggagca cgccgacctg tccgtgtgtg   1320
ttgtaggcag gtacatctac gctgtggcgg gccgtgacta ccacaatgac ctgaatgctg   1380
tggagcgcta cgaccctgcc accaactcct gggcatacgt ggccccactc aagagggagg   1440
tgtatgccca cgcaggcgcg acgctggagg ggaagatgta tatcacctgc ggccgcagag   1500
gggaggatta cctgaaagag acacactgct acgatccagg cagcaacact tggcacacac   1560
tggctgatgg gcctgtgcgg cgcgcctggc acggcatggc aaccctcctc aacaagctgt   1620
atgtgatcgg gggcagcaac aacgatgccg gatacaggag ggacgtgcac caggtggcct   1680
gctacagctg cacgtctgga cagtggtcat ctgtctgccc actccctgct gggcacggtg   1740
agcctggcat tgctgtgctg gacaacagga tctatgtgtt aggtggccgc tcacacaacc   1800
gcggcagccg cacaggctac gtgcacattt acgatgtgga gaaggactgc tgggaggaag   1860
ggccccagct ggacaactcc atctcaggcc tggcggcctg tgtgctcacc ctgccccgct   1920
ccctgctcct tgagccgccc cgcgggaccc ctgaccgcag ccaggccgac ccggactttg   1980
cctctgaggt gatgagtgtg tctgactggg aggagtttga caactccagt gaggactagg   2040
ctccctgtgc ctggcatcag agggaaggga ggctggggct gcagggcagt gaaacccacg   2100
cagcctaggc cagagcactt tactccaggc agggcccctg cccctgttgg ccacagctta   2160
tgggccctgc cctctttctt cacaccagcc ccttggccag cctgccgcag gcatctcagg   2220
gccrtgcaga tcccaggctg tggattacgt cactgcagga actgcttctg aaaggctttg   2280
gmcttcctca gtgagccctg gaggggttgg ccttctctcc tccctgccta gatcagtcct   2340
tctccaaaag gacctgggag ctggcagcct gggcaggggg gctgaggcac gtggtagccc   2400
tctttctgtg aatggggtgg ggctgtgggg gcagctgggg ttggaggatg agagctcctg   2460
aggggcagag gagcagagat gcatcagctc gcctgggact ggctctgtga taaaaagacc   2520
cctccgctgg gttttcagac cccatgttgt tggtcaatga aataaagcat cttacagaag   2580
gtgttaactg ttaaaaaaaa aaaaaaaaaa taaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2640
aaaaaaaaaa aacccacgcg tnccg                                         2665

<210> 1372
<211> 2771
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (448)
<223> n equals a,t,g, or c

<400> 1372
cagggatgag gctgagaaat gtgtcgwgat cgccgggagg ccctgaacgc cggcaaccgc     60
gagaaggccc agcgcttcct gcagaaggcc gagaagctct acccactgcc ctcggcccgc    120
gcactattgg aaataattat gaaaaatgga agcacggctg gaaatagccc tcattgccga    180
aaaccatcag gtagtggcga tcaaagcaag cctaattgca caaaggacag cacatctggt    240
agtggtgaag gtggaaaagg ctataccaaa gaccaagtag atggagttct cagcmtaaac    300
aaatrtaaaa attactatga agtacttgga gttacgaaag atrstggtga tgaagatttg    360
aaaaaagctt atagaaagct tgctttgaag tttcatccag acaaaaacca tgcacctgga    420
gcaacagatg cttttaaaaa ggttgggnaa tgcttatgct gttttaagta atccagaaaa    480
gcgaaaacag tatgacctca cgggcaatga agaacaagca tgtaaccacc aaaacaatgg    540
cagatttaat ttccatagag gttgtgaagy tgatataact ccagaagact tgtttaatat    600
attttttggg ggtggrtttc cttcaggtag tgtacattct ttttcaaatg gaagagctgg    660
ttatagccaa caacatcagc atcgacatag tggacatgaa agagaagagg aaagaggaga    720
tggaggtttt tctgtgttta tccagctgat gcccataatt gtattgatcc tcgtgtcatt    780
attaagccag ttgatggtct ctaatcctcc ttattcctta tatcccagat ctggaactgg    840
gcaaactatt aaaatgcaaa cagaaaactt gggtgttgtt tattatgtca acaaggactt    900
caaaaatgaa tataaaggaa tgttattaca aaaggtagaa aagagtgtgg aggaagatta    960
tgtgactaat attcgaaata actgctggaa agaaagacaa caaaaaacag atatgcagta   1020
tgcagcaaaa gtataccgtg atgatcgact ccgaaggaag gcagatgcct tgagcatgga   1080
caactgtaaa gaattagagc ggcttaccag tctttataaa ggaggatgaa ctggaatttt   1140
tatttatacc ttttagcgta ctctttattt tttctgtaag taagtttggt ttcatcatga   1200
gggatgaagg aaaagatttg atactgaaaa ctaaactgaa tagttggttc ctgaaatctt   1260
ggactgttta tgacctactg gctcctttaa atagtaactg aaaactaaaa tggaatattt   1320
tagttaacgc ttctacaagt attttcattt taaaagctta catgattcct aactaaagtg   1380
tcatgagaaa ggattatcac acctgtagca atttccagtt ttagtgattc tccatttttt   1440
cccttgtcat gtaaatattt atggaatgat cattttgtgt acatacaggt tactgctttt   1500
ttatttaaat tcttttagtg tttagctcca tgagacactt cagtttaaat tgatggaata   1560
aatgttatat gacacattta cattttcctt atcaaggtgt caaatatgtg gactttaaac   1620
aatgaaactt tttcaaaaag aaaaamcaaa aactttaact ttgtgtaaaa tcttatagta   1680
ttatcagctt agagggaatt gatattttta atattgccgt tatattccaa aatatatatt   1740
gagataaatg aactggtgta gaatatcagt ttgctattta gttttatgaa ttactataca   1800
tatacatgca tagaaatgaa atgctatact gataaatttt aaagaaaata tgaggaaatg   1860
gctataaata ttaaactaaa agggtcttca acagtaaagt gcagttatgt catttaaaat   1920
tccaatactt taaaggccac caaattttga tgtatatgtc cttgaagggc tgctaaaatt   1980
tatgaagagg actcacattt tcccccatag aaatttgcag tttcttggtg atcatttaag   2040
caggatccaa agaagttcct ttacaaataa gtaataagaa aaatgagtac taaaatacag   2100
ctttgtgcct tttaacccta tgccaactcc taaacatata agtagattac agtatactta   2160
tctgatcaga gcatgatctg tttggccaca tgcaagtgtg agcagaaata gagcagcacg   2220
tagaatagta acttaaagca agtcatcctt taaaaattct gagctaaaat ctatttacca   2280
ttgagtaatt gaattaatcc cataggaata agctccttgt aagtaaatcc atgatatgaa   2340
ttagaaaaaa aaaacagctg gaaattgaag tttttgatgc ctgtatactg gatatgaaac   2400
tatttgattt ctagtcttct gtgtttagca gttgtaatat tttaatgatt ttgcttcata   2460
ctcggttaat ggaacataaa catatctttg atacttcttt gtgagtgaga gaatgctaga   2520
tagggtggct ttgttctttg tttaagtttt ttttcctgaa tgtagttaat ttatggcatc   2580
tgttgaataa aactgctaaa atgacctctt aaaaatgttc tgttgtatcc ccttttccag   2640
gtgaatcaat agaaatgcct gattgaatta gtaggttaaa ctaaacaaca tactgtcata   2700
ggaaaactgg agagcttaac caacttgctc ttagaaatgt taccttaaaa aaaaaaaaaa   2760
agggcggccg c                                                        2771

<210> 1373
<211> 1178
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1147)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1176)
<223> n equals a,t,g, or c

<400> 1373
agggatttta cacggtgtat cgtaatgttt ttgaaatgat tgccaaggaa gaactagaat     60
ctgtgttaga ggaagaggtt gatgatttcc caacttttgg agactcccag agtgactatg    120
atacggtagt ccatcctttc tacgcttatt ggcagagttt ctgcactcaa aagaattttg    180
catggaagga agaatatgat acacgacagg cttcaaaccg ctgggaaaaa cgagccatgg    240
aaaaagaaaa caaaaagatt cgggacaaag caaggaaaga gaagaatgag cttgtccgtc    300
agctggtagc tttcattcgt aaaagagata aaagagtgca ggcgcatcga aaacttgtgg    360
aagaacagaa tgcagagaag gcgaggaaag ccgaagagat gaggcggcag cagaagctaa    420
agcaggccaa actggtggag cagtacagag aacagagctg gatgactatg gccaatttgg    480
agaaagagct ccaggagatg gaggcacggt acgagaagga gtttggagat ggatcggatg    540
aaaatgaaat ggaagaacat gaactcaaag atgaggagga tggtaaagac agtkatgagg    600
ccgaggacgy tgagctctwt gatgaccttt actgcccagc atgtgacaaa tcgttcaaga    660
cagaaaaggc catgaagaat cacgagaagt caaagaagca tcgggaaatg gtggccttgc    720
taaaacaaca gctggaggag gaagaagaaa atttttcaag acctcaaatt gatgaaaatc    780
cattagatga caattctgag gaagaaatgg aagatgcacc aaaacaaaag ctttctaaaa    840
aacagaagaa aaagaaacag aaaccagcac aggatgtacc tggcaaagat tcatatctgc    900
ctgcagctca ctttcagatg gcttggggaa aaaagtgtgt gttgggagag agaagagatg    960
gagagagcga gcacaaatgt gccaaaatgt tgcttgaaaa cagacaggta cgcttaggat   1020
atgtttgcca ggcgtctttc ttttataatg cctgtttgtt gttgccattg tttgtgactg   1080
tagaagaata gttgctcatt gcttatcatt tggaatatgg aaaagtatca tccttaattt   1140
tacctgnaga gattacttaa taaagaatta aattgnga                           1178

<210> 1374
<211> 558
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (478)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (502)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (505)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (510)
<223> n equals a,t,g, or c

<400> 1374
ctggagaaaa acttacaaat gtaaacaatg tggtaaagcc ttcatttccg caggttacct     60
tcggacacat gaaatcagat ctcacgcgct ggagaaatcc caccaatgtc aggaatgtgg    120
gaaaaaactc agttgttcca gttcccttca cagacatgaa agaactcata gtggaggaaa    180
actctacgaa tgtcaaaaat gtgccaaagt ctttagatgt cccacgtccc ttcaagcaca    240
tgaaagagct cacactggag aaagacctta tgaatgtaat aaatgtggta aaaccttcaa    300
ttatcccagt tgttttcgaa gacataaaaa aaactcatag tggagaaaag ccatatgaat    360
gtacaaggtg tggtaaagcc tttgggtggt gcagttccct ccgaagacat gaaatgactc    420
acactggaga aaaacccttt ttttgtaaac agtgtggtaa agtctttact ttttcaantt    480
accttagact tcaggaaaga antcnttggn cgggcgtacc agttgctttt ggcaggaggc    540
aggggggtcc accccccc                                                  558

<210> 1375
<211> 1831
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1803)
<223> n equals a,t,g, or c

<400> 1375
gcgtccgcsg ggctgggcgg cggggacagc ggggacggca cggcgcgcgc acttctaagt     60
gccagatgat ggaggagcgt gccaacctga tgcacatgat gaaactcagc atcaaggtgt    120
tgctccagtc ggctctgagc ctgggccgca gcctggatgc gacmatgccc ccttgcagca    180
gttctttgta gtgatggagc actgcctcaa acatgggctg aaagttaaga agagttttat    240
tggccaaaat aaatcattct ttggtccttt ggagctggtg gagaaacttt gtccagaagc    300
atcagatata gcgactagtg tcagaaatct tccagaatta aagacagctg tgggaagagg    360
ccgagcgtgg ctttatcttg cactcatgca aaagaaactg gcagattatc tgaaagtgct    420
tatagacaat aaacatctct taagcgagtt ctatgagcct gaggctttaa tgatggagga    480
agaagggatg gtgattgttg gtctgctggt gggactcaat gttctcgatg ccaatctctg    540
cttgaaagga gaagacttgg attctcaggt tggagtaata gatttttccc tctaccttaa    600
ggatgtgcag gatcttgatg gtggcaagga gcatgaaaga attactgatg tccttgatca    660
aaaaaattat gtggaagaac ttaaccggca cttgagctgc acagttgggg atcttcaaac    720
caagatagat ggcttggaaa agactaactc aaagcttcaa gaagagcttt cagctgcaac    780
agaccgaatt tgctcacttc aagaagaaca gcagcagtta agagaacaaa atgaattaat    840
tcgagaaaga agtgaaaaga gtgtagagat aacaaaacag gataccaaag ttgagctgga    900
gacttacaag caaactcggc aaggtctgga tgaaatgtac agtgatgtgt ggaagcagct    960
aaaagaggag aagaaagtcc ggttggaact ggaaaaagaa ctggagttac aaattggaat   1020
gaaaaccgaa atggaaattg caatgaagtt actggaaaag gacacccacg agaagcagga   1080
cacactagtt gccctccgcc agcagctgga agaagtcaaa gcgattaatt tacagatgtt   1140
tcacaaagct cagaatgcag agagcagttt gcagcagaag aatgaagcca tcacatcctt   1200
tgaaggaaaa accaaccaag ttatgtccag catgaaacaa atggaagaaa ggttgcagca   1260
ctcggagcgg gcgaggcagg gggctgagga gcggagccac aagctgcagc aggagctggg   1320
cgggaggatc ggcgccctgc agctgcagct ctcccagctg cacgagcaat gctcaagcct   1380
ggagaaagaa ttgaaatcag aaaaagagca aagacaggct cttcagcgcg aattacagca   1440
cgagaaagac acttcctctc tactcaggat ggagctgcaa caagtggaag gactgaaaaa   1500
ggagttgcgg gagcttcagg acgagaaggc agagctgcag aagatctgcg aggagcagga   1560
acaagccctc caggaaatgg gcctgcacct cagccagtcc aagctgaaga tggaagatat   1620
aaaagaagtg aaccaggcac tgaagggcca cgcctggctg aaagatgacg aagcgacaca   1680
ctgtaggcag tgtgagaagg agttctccat ttcccggaga aagcaccact gccggaactg   1740
tggccacatc ttctgcaaca cctgctccag caacgagctr gccctgccct cctascccaa   1800
gcnggtgcga gtgtgcgaca ctggccacac c                                  1831

<210> 1376
<211> 1159
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1040)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1120)
<223> n equals a,t,g, or c

<400> 1376
gggcttttcc ggaaggagcg gctcggtgtt ggggctaggc cggtattcta ggcccaagcc     60
caggcccagg cctgtgttcc cggcccttgc tcaaagacag gccggtggcc gctgcgacac    120
tctaggtaca gcggagggcg cagcgggccg ttcgctgagg tgtccggacc cgccgccgag    180
cgggccgtgg agccacagta cgtggcggcg cctcttcctt gcccgaagcg gaactgctga    240
aggagcggca rcgcaggccg gacgaggtga accaggtcat ttaaccgcct tcaggtgatg    300
aatcatctgt ctaataatca gatttgaggt ccacagccct ttgtggtcct gctacarggt    360
gattttcart ggatgactga ctggcgtggc ccgaggggtg ccgcagtgac tgccttccct    420
tgataaggaa acgagctttc tgttctttct ggacacctcg ttacctgtaa aacattccgg    480
ktataacttc tttatccggc ttgcatctct gtgcaagagg aaagctttca catgaaagtg    540
tcccttggta acggcgaaat gggcgtctct gcccatttgc agccttgtaa ggcaggaacc    600
acacgctttt ttaccagcaa tactcacagt tcggtggtat tgcaaggctt tgatcagctt    660
agaatagaag gattgctttg tgatgtgacc ctggtaccag gtgatggaga tgaaatcttc    720
cctgttcaca gagctatgat ggcgtctgct agtgattatt tcaaarccat gttcacaggt    780
ggaatgaaag aacaagattt gatgtgcatt aagcttcatg gggtgaacaa ggttggtctg    840
aagaaaatca ttgattttat ttatactgca aaactttctc ttaatatgga caatcttcag    900
gacacacttg aagctgctag ctttttacaa atattacccg ttttggattt ctgtaaagta    960
tttcttatat caggagtctc tttggataac tgtgttgagg ttggacgaat tgctaacacc   1020
tacaatctta tagaagtggn taaatatgtt aataatttca tcctgaagaa ctttcctgct   1080
ttattgagta ctggggagtt tctaaaactc ccttttgaan gacttgcatt tgtgctttcc   1140
agtaatagct taagcactg                                                1159

<210> 1377
<211> 527
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (458)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (487)
<223> n equals a,t,g, or c

<400> 1377
gaattcggca gagctgagaa accctacgaa tgtaaggaat gtggcaaggc ctttcgtcat     60
gccacaagcc tcatatatca tgaccgaact catgctggtg aaaagtccta tgaatgtaaa    120
gaatgtgggg aaacttttag tcatgcttca catcttatta ttcatgagag aattcatacc    180
agtgataaac cctatgaatg taaaagatgt gggaaggcat ttcactgtgc ctcatatctt    240
gttagacatg aaagcgttca tgctgatgga aatccctata tgtgtgaaga gtgtgggaaa    300
gcttttaata gtagccatga acttagtata catcatagrg ttcatactgg tgagaaaccc    360
tttaaatgta acaaatgcag aaggtccttt aggcttagat ccatccttgg aagtacatca    420
gaggaattca tatttggtta gaggaattgt gggcattnta caggtaggta aaggaaaggc    480
acattgngtc catggatttt atccccactg gaacattttt ggattgg                  527

<210> 1378
<211> 2937
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> n equals a,t,g, or c

<400> 1378
tgccaaaagg ggattttctt ccaagccgat ttaagttggt taccccangg tttttcccag     60
tccacgacgt tgttaaacga cggcccatga attgtaatac gactcactat agggcgaatt    120
gggtaccggg ccccccctcg agtttttttt tttttttttt ggctgtggtt gtaggaacca    180
ccctacagcc tagaagactt tattaagatc ttattgctta tgcagttaaa gagacactga    240
ttgagctaca ggtttcctgt acctggtctc aggtcactct gtgcagagct tccccaggct    300
gttgggagct gggagactgc taggcagggg caggccccag agtgggaagc atggtacctc    360
ctaggagcct cagagtgggt agcgggcttc aagacagccc tcagggtgaa cagagaggtc    420
aggagtgtcg gcttaagcca gggcccaggg gctacattcc ctgagatgag tcaagcccag    480
ccctctctgg ggtttccaga acaaaggcta ggtgtgggga gcagcactgt ggagagggca    540
gggagcatgt ctctaggcat tgctggaact ggaggagact gtcagagtgg tttgggtaat    600
ggttgtataa tctgtggcaa ctgggccttc ttgcatgaaa gtggaagggt gaggatccct    660
tatggaagag tcatgcacca tggctgggct ggactagcca gctccagtgg ctctgctggg    720
tgactaaagt aggcaaggaa agccacttgt tgcccacacc ccactttcat caactctgtt    780
catgcaggac aaagcaggga gctgcccaac aaggatgggg ttatttctca ggcctaggta    840
ttgatgttac cttaattctt tagtctggaa gaacttggtt gggggtgggg gatggtaagc    900
atttccttaa ccaaacccac acttcacatc tcctaggggt accccttcat ccaccaacct    960
ccagagaata acctggctgc cctcacttct ccagcttttc tcacaaggca cttgttacag   1020
ggctgctgat gggagaggga ggaaggcctg ggagggggat ctggtggtgg cgcccaatct   1080
acagggtccg gaatcagggt ggaagttgtc agggactagc ggctgccata gtacaggcgc   1140
atggccaggc caatgagcaa tgtggccagg aagaaggcgg ctgtgagctg cagccgtagc   1200
aggactgctg agagcacggc gttgaccacc agcgagcagg acaccacaaa gaggcgtgtg   1260
atgctgctgc catgcttcat gacagcagac atgagcagtc catttagtgc ctggctcagc   1320
accacgagtg ctgcccatcc tgagaaacct tccaggaggc ctgggccaga gccgccgcca   1380
gcatgcagac ctagattcag aagcacacca aaagtgtaga ggaagaggtt ctgaagtgcc   1440
aggggcagcc gctgtcgctt catgagcagc tctgtgtaca ctgacgacaa gcctgagatg   1500
aggcagtaca gaatgaggag cagcaggcct agcggagtga tatgcagggg catggggctg   1560
gcagcagctg ctggaggggg actgggaagg gtgttcccgg gaacttgaag gccccctgct   1620
gcatagcagg ctcccgcagc catcagcagc agcagcgcta acccctgacg cacagagagg   1680
cggtgccgga ggcagaggca gtagagcaca gctgtgcttc caatcttgag attactcagc   1740
acctggtagg tgctggggtc catgtaacgc tgaagataga tcaccaggtt gttgttagcg   1800
ccatagagca gggctgatag tgcgaaggga gcagcctggc gccagggtgg gggcccctgg   1860
ggccatgctt gccagcctac cagaagggag aaggcgcata acagtagctt ggtcagctca   1920
gtcagcagca cggctgagga gggccggaag ggcactcggc cgtccacatg gcacagtgcc   1980
agcaatgggg catgggcacc gtacatggca gtggatagga gtagcatcag ggtccagcgg   2040
gcctgcctgg gacggcccag gcctggcata cccccatcct ctacactcat acccacacaa   2100
gaccctgggt ggctaagggg cagcagggat tgcaacacgt ttggggaaaa tcaagttatg   2160
gagccagctc ccaggaagga gaagccgtgg aacattgcca gagagaatac tgaggatyag   2220
aggcatctac caactccaca gtcagggctt gaagagtaag gggctggtgg tccttgaagc   2280
cacagtcttg gggcgagtcc catggagcta ggaaggggaa gaaggaatcc agggtgcagg   2340
ctgaggaact actgtccaca atctgcagga agggaggcaa ggatgaaggt ggcaggaaag   2400
ttggagatag caaatggatg acagctgggg aatccagata aagtgtctcc acctgaaggc   2460
tgagctgctc atcctgcctc ttccatggca cctagagcta gtcgggcccc ttgcgtagca   2520
actgcaaata gtcccttaat gtcttctcca cgttgggcac agcatatgcc tgagccgcat   2580
agatgccagt gcaggtgccc acagcaaagc ccaatactgc tgatgccctc agtttggcca   2640
ccacatagcc agccaggaat cccttgagga acggggagga caacagcgag ccatcctggc   2700
ccactccact gttgacttcg tcttctacac gccgctgcag gctttccagc tggttcttga   2760
gaaatgccag gtccttaagc ttaggcagag aatcctagga caagcgagag gctggctcca   2820
gcagtctgac taagccccac cccttgctca attccatcag aagctgggaa ttgggagggg   2880
atggggtgag ccagaaagac cttttcctat aaaagcttcc ttgtcatccg ccatctc      2937

<210> 1379
<211> 1975
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (119)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (753)
<223> n equals a,t,g, or c

<400> 1379
atagggagat agctatgacg tcgcatgcac gcgtaagctt gggcccctcg agggatcctn     60
tagagcggcc gccctttttt tttttttttt tttttttttt tttttttttt tttttttkng    120
accgtgaacc atttatttcc aaactataaa gaaacctgct ctctgagaaa agacactgcc    180
caggtgatga agctccagcc cctggaggtc caaaacccag tccaaactca gtccctttag    240
aaagctgctg tgccttggaa atgagtctcg gctgtcagag cctgggaagt ggtgggaaga    300
accagcccac tcccctctcc tgctgcgatt ccagcgcagc ttgggcccag ctctggccag    360
tcccaggctg gcctggtgct cgccccttgt gtgaccaggc tctgaaggga ggggcaaaag    420
tcatgagtcc ctggcttggc cccaccacct ggtgactccc gtccacagct cccagctacc    480
atgatgagcc ctggcggctt gagcacagtg agtgctggca gcaggctggg gagtggcctg    540
cttctaagcc atttgccctg gctggtcact gctgcccctg ggccacaaag tactcctcct    600
cctcattgtc accttcctcc cgctggctgc tccggagcag cagctccagg tcggggctgg    660
agcccagccc cttcaaggcc ttggggccac catcacytct ggaatgcagg gctttgaggg    720
caacgtggag ggatattccc gagaggcaga ggncgaagcc cagccagttc aggaggctga    780
tctgatcgcc cagcagatga gctgccaaca gcaaagtgca gacttcctta aaaatgccgg    840
caatggagag agtgaggctg gaggttctgg agaccaggag gaactcagag aagcccaaac    900
caaaggcgag aatcccgcca aggaagaggc tcccaagtac ccgcaggagc agccctgtgt    960
cctggaaacg gaagattttc tcagatgtgg acaaatggag accttcaaat acagcaaaga   1020
gagggaagag ccccaggaac atgagtggct gcaggtggaa catggtgtcg atgggattct   1080
ggaggccgag ttcagccttc tgcaggagca tctgggtgag ggtccagcga atgccaccga   1140
tgaacgaggc ccccagcacc aaggcgaagc cctccacgtt gaactgtgtg gacttgtagg   1200
tgaacatgaa gagacccccg gcgatgagga ggaccaccag gaccagtgcc gcgcgcagct   1260
cctccagctt gaagatcaga gagaagatca agatgaagag gacagctgag gatttggtca   1320
ttgtgtacag cgagacggtg acatacagga agctccagtt ggacaagccc acgtcaagcg   1380
ccgtcgccag agctgtggga gccactcttc tgaggtagtc ggcccagctc agcaccacac   1440
gggccctgtg gctggagcac tgaaccagcg ccctggacag ggcggagaag aggaagatca   1500
cggccaggtg cagcatcgtc atgaagaggg ggaaatggaa gctctttgtc agccacttgt   1560
tgtagaaggt gatgccgatg gagaagcagt agtagagaag caccagcccc agggtcaaca   1620
ccgccttcca caaaaaggcc acatcgaggg cccacctccc cattcgtggc ggctgcagca   1680
ccggagctcc tgagtcagcg ggggcaggca cccctcttga atacaatgtg caggaagagc   1740
cggtggagtt agaccacagc tttcaccaag aacgtctcca ggctggagga gctctctgca   1800
gctccatgat tcggaaccat cagcagagcc ccaggcagag tcctcaccta aggggctggt   1860
ggctggtgct gacccttccc atggttaatt ggatgcagcg ctcacaggtc ccaaggtctg   1920
ctcggccctg ggagctccag gccggaatct ccccaccgga agtgcgaggc cggct        1975

<210> 1380
<211> 2049
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (48)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (322)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1819)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1987)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2021)
<223> n equals a,t,g, or c

<400> 1380
cggtcacgtt gngcgtaacc accacacccg ccgcgcttaa tgcgccgnta cagggcgcgt     60
cccattcgcc attcaggctg cgcaactgtt gggaagggcg atcggtgcgg gcctyttcgc    120
tattacgcca gctggcgaaa gggggatgtg ctgcaaggcg attaagttgg gtaacgccag    180
ggttttccca gtcacgacgt tgtaaaacga cggccagtga attgaattta ggtgacacta    240
tagaagagct atgacgtcgc atgcacgcgt acgtaagctt ggatcctcta gagcggccgc    300
cctttttttt tttttttttt tncacatgag aagtgtcagt ttaatgaagc cagcttatca    360
gcagggcggc ggagcacacc tgccccctcg caggtgtgcc tggctcgggc taaagtgcct    420
gtgcagaacg aggctgcctg gcggggttag gagtcggcgc cctcgtcctc ctcctcgggc    480
aggatctcca ggctgctgtc gggctgcggg gctgtgtccg tggagggcgg cggggtgggc    540
ggggcccggg tgggcgacag aggcagcggg gaggcggtgg gcgaggggct gtggggctct    600
gcgggcgggg ccagccccag gatctcctgc acgttgtggg gcagctcggg gcaggcggtt    660
agctggcggt gcagggcctc ggcgcgggtc agcacgtcct ccacgctcag cttcatagtc    720
agctcgttga tgtgcttgag gatctcattg gagccgaagc cggacagcat gagggtgtcc    780
ctctccatgt ccaggatggc gcaggccacc agcaggtgca gattggggcc agggagccct    840
gtccacagca cctcccacag ccgaaggaca tccgggaagg ggaattccct cttgaaccag    900
atgagcagcc accggaaaca gaagcagaga gagccggagt cctgggaatc caggaagtcg    960
cagagcaggg ggtccagcac cctcaggagc agcagcagtc gcccgagttg ccgcttcatg   1020
gtctcctggc tctcttcaaa gttcccttgc acgagctcca tgaagccaca gaaacaccag   1080
aaagcatcca cctcgttctg aatgacgtag aggatcgggg agagaagatc actcatgccc   1140
tggacgtagc cgaggtcgaa gtgatacatg cagtaggtga ggaggatatc gttcagcagg   1200
cccagccccg ggttctcggg accctcgtag aacttgttgg tcctgtcagt gcggctcaca   1260
tccctttcga tgaggctgcg gtatccatgc agaagtgagt ttctccgctc ctgctcaggg   1320
ctcacagatt tccactgcag cttcatgcgg aaatactcat ccgttttctt gcgtatgtgg   1380
gccttgtgct cctcagctgt gccttcccag ctgaggtacc ctaggaggaa cttccaggcc   1440
tcgcgccgca ggctggggct cagacccccc gagaagatcc ggttcttcag ctcagggacc   1500
tgctgcaggc gaccttcagg gcccacgtgg cgtgcccact cctcctctgt aactggaggg   1560
cccgctccac ggttgccgag gccccagctc cacacaggaa atgacctcga atccaggctc   1620
gggctcatcg tcgggtggcg ggggaaggtc ggaggcggct ccctcaggct gtggctgcag   1680
ggcaccccgg aagaagttgg tcactcggga gaagctgctg aaggtggtgg agtagggatc   1740
ctggaggaag cgctggggac gaggccaaag ggaggtcacg gcccgcccct tstcgtccct   1800
ccctgcccac acccgccang cctcctgctg gggacactca cttgacaaca cattggagct   1860
gtcctggtca aagagctgca ggtggtggga aggagtttgg gagagagcag aggagtcgtg   1920
gggggaagac aaggtagagg cgggaktcct gcggggagct gggaggcggg aggtgacgca   1980
cagttgntgc acagttaggg gcccattttc ccagttgttt ntgtttggcc gacatcgttt   2040
ccattgcag                                                           2049

<210> 1381
<211> 2476
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (14)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (18)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (23)
<223> n equals a,t,g, or c

<400> 1381
ncgggggcac ctangaantg gcnaccgggc cccccctcga gttttttttt tttttttttt     60
ttgcaatttc atagttttta ttcagtggac ttaaagccaa gaaaccatcc caataattat    120
ttacaattta ataactgaat gattatcaga tcgtgttata ctgcaaaact gttcttacac    180
catgaatgct gatgctgtga actttggatg ttaaactggt aaaagctgga ggcttcaaat    240
ggcatatgca aatgtaacca aagcctgagg actatgaaga aagaggagtt tctaccactc    300
ggcatttata gtttttatat gcattgcaga agcatgggga attaagtgat ctctgaaaaa    360
aatgctttaa aaaactgagt atacatatag cctataaggt aaaaatccaa gttacaagtg    420
tattaaacac tggcaactat gttatcagag ggaatactga attatatata tacataaact    480
gtcattaaac tgtgattaca tgatacttcc taccacagct tattagactg tacaacagaa    540
gatattcctg tggctctcta aggctccagg tttaaaagaa tttagtattt tccccttggc    600
tcaaagtcta atcagtatca ttctataaca taaatcagaa actacgcttt ttgcttttaa    660
ggaaataaga aacataattg caaccattac agctccaaca tacactgcaa aaatgatatc    720
tacaagcagt tgccattgca tttgaaaaat gcattttctg aataagcttc acttagtacc    780
aaggatgcct ttcaagtcag cttctacatt ctgaatarag tacataatgg gatttaagta    840
aatctttaga agtcccggag tttgcctttt ctaacatttt catatcaggt gaaaacaatt    900
ttttcatatg ggtgattgta tttaccaaca tgagcaaatg tctacagaag aatgcgctgt    960
tctatatgtc tgtaaggaat ctgcacttaa ctggaaacta cagggtccat cagaaagtta   1020
aatttaaaaa agatcagcca tagccaagtt cttcgtagat tatgaaaaaa aaatggcact   1080
gataggtcta ggttctgaag aggggccacg gwtgaatgga aatgcttcta catgggacag   1140
gaatgtcgtg aatctggagt tctcgggtct cttggtggca gaagacgccg tctgtgcgtc   1200
tcacagtgct ttctgatgcc catttacaga aggcttggct gtttctgaat cccttgaagt   1260
atttggtaag tgaagtttat gaagccctag ggccttgaaa agttcttctc gaactgcaga   1320
ggtgaatttt cggaccagac acaatgttgt cacaatagca aaaagcaaat tgtaggataa   1380
tacaatatag aaatttccca gccaattaaa ccttccaaag tcgccaagta gatcaaatct   1440
agtgattccc agtgttctcg acatcacagg cagagcagag ctcaaaacca agatggacac   1500
acaatttcca atgatctttg tcatagttgt gtcatctttc ttgggagtaa agtttccaaa   1560
aaatcgaagg ctatagaagc cgacaacaga ggacaccata agatagaaaa tcaaaatgat   1620
ttcaagcgca gctcccacaa aaccaaacgt agaaagagag gcatttccta ttccaggccc   1680
ccttgttcct tttggcattg ctgtttcatc aaccaatagg caaagaatat tacaagccac   1740
caagaggacc gagatggatg tctcaataag aaggagaacc ataacagcgg gatacaccaa   1800
atttctttcc catgctgaag ccttttttcg cctctctaat tttgtcttaa gagtctttac   1860
attttcaagt tcttgttcca actccattat gttgtattcc accgatgaag acagcccatt   1920
tagtcgtctc tggagtgctt cttcctctaa ggtaatgata taaatttgtt catccaggtc   1980
ttcaagaatt gttggcttca ctagcaactg acccatcact gtgaacatac gagaaaggcc   2040
aactggtgta cacaagagaa gtaacaaaca tcccatcaat gatatacagg aatataaata   2100
gggtagatag aactcccaga gatcatataa agattccatg cttgcggcat cgttgtcaat   2160
gagtgctgaa gctacccaca ctatcccaag aatgagtaac gcaagaagaa gaagcatgac   2220
caaagtctct aaaatgcggg ctcggattcc ctttttcagg ccagcaaagc cttctgattc   2280
cagaaagaaa aaggcaaagg gcatcaatac aaataarcaa aggttggaaa aaagggaagc   2340
aagattccac aaaccatgaa tcagggagcc atttagccac tgaatatagt agttctgagg   2400
aaaagaaagc aggatttcat tgctgctcgt gccgaattcc tgcagcccgg gggatccact   2460
agttctagag cggccg                                                   2476

<210> 1382
<211> 1409
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (700)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (985)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (999)
<223> n equals a,t,g, or c

<400> 1382
tggagctcca ccgcggtggc ggccgctcta gaactagtgg atcccccggg ctgcaggaat     60
tcggcacgag cgggggtgta ggtgccaagc gccatggctt agacccgaga ttggagtccg    120
gccgcccccc gacagcagcc gcctcctgcc ccccgtgcgc cctaggcgcc accatgtcgg    180
gagacaaact tctgagcgaa ctcggttata agctgggccg cacaattgga gagggcagct    240
actccaaggt gaaggtggcc acatccaaga agtacaaggg taccgtggcc atcaaggtgg    300
tggaccggcg gcgagcgccc ccggacttcg tcaacaagtt cctgccgcga gagctgtcca    360
tcctgcgggg cgtgcgacac ccgcacatcg tgcacgtctt cgagttcatc gaggtgtgca    420
acgggaaact gtacatcgtg atggaagcgg ccgccaccga cctgctgcaa gccgtgcagc    480
gcaacgggcg catccccgga gttcaggcgc gcgacctctt tgcgcagatc gccggcgccg    540
tgcgctacct gcacgatcat cacctggtgc accgcgacct caagtgcgaa aacgtgctgc    600
tgagcccgga cgagcgccgc gtcaagctca ccgacttcgg cttcggccgc caggcccatg    660
gctacccaga cctgagcacc acctactgcg gctcagccgn ctacgcgtca cccgaggtgc    720
tcctgggcat cccctacgac cccaagaagt acgatgtgtg gagcatgggc gtcgtgctct    780
acgtcatggt caccgggtgc atgcccttcg acgactcgga catcgccggc ctgccccggc    840
gccagaaacg cggcgtgctc taccccgaag gcctcgagct gtccgagcgc tgcaaggccc    900
tgatcgccga gctgctgcag ttcagcccgt ccgcaggccc ttccgcgggc caggtagcgc    960
gcaactgctg gctgcgcgcc ggggnaytcc ggctagaanc csggtggttc cagccattcc   1020
tgcagccaag ggcactgggc cagggcggcg cacgcgcaag argcgcgctt cgagggaata   1080
tgcgaagctg ccgcgtgctg ctgcacatgc gctttttccc ttccgcttcc ctccctttct   1140
tcccacgggg gartccgcag ttgcccttgt tcggaatcca cgttccccgc gatcccggga   1200
gctggaggcg catgcgcatc cgcgattccc tgcgaccagg ccccgagagg gcgagaccag   1260
aggggacgga agcattgcgc ctgcgcggaa ctctcagcct ctgcgcggag ggcgtccctt   1320
cccaaccagc cgtgggtgcc aggttcccgg ttggaacctg caataaactc gctgttcctc   1380
gcaaaaaaaa aaaaaaaaaa aaaactcga                                     1409

<210> 1383
<211> 1764
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1587)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1594)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1736)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1747)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1750)
<223> n equals a,t,g, or c

<400> 1383
aaaaacaaaa acaacaacaa caacaaaaat tttttaaagg gggagtgaga tgggagagaa     60
gggggcctta tttctcggaa accagccctg ctgccctctt cccatggcca caggagcctc    120
cccagtgacg gagttgtgag attgggggtt tctggtgtcc tgacttccgt cccagggatc    180
accttgggtt tcccacgttg cagagactaa ctgaaaggac atgagggctt taccctggga    240
atgctctgct ggggcaggtg ggtgttagct gcgattctgt gttattttcc catcctcaga    300
ggtctgcggg gtttccgaga ggctcgccgg gatttctggc ggggggctga gagcctggag    360
gctgccctga cccacaacgc agaggttccc aggcgccggg cccaggaggc agaagaggca    420
ggagctgctt tgaggacggc tcgagctggg taccggggac gggcactgga ttatgccctg    480
cagatcaacg tgattgagga caagakgaag tttgacatca tggartttgt gctgcgtttg    540
gtggaggccc aggctaccca tttcagcagg ccatgaggag ctgagccggc tgtcccagta    600
tcgaaaggar ctgggcgccc agttgcacca gctggtcttg aattcagcac gagagaagag    660
ggacatggag cagagacacg tgctgctgaa acagaaggag ctgggtgggg aggagccaga    720
accaagctta agagaggggc ctggtggcct ggtgatggaa ggacatctct tcaaacgggc    780
cagcaacgca tttaagacct ggagcagacg ctggttcacc attcagagca accaactggt    840
ttaccagaag aagtacaagg accctgtgac tgtggtggtg gatgaccttc gtctctgcac    900
agtgaactct gccctgactc agaaaggcgg ttctgctttg aggtkgtgtc caccagcaag    960
tcctgcctcc tccaggctga ctcagagcgc ctcctgcagc tgtgggtcag tgctgtgcag   1020
agcagcattg cttctgcctt cagtcaggct cgccttgatg acagcccccg gggtccaggc   1080
cagggctcag gacacctggc cataggctct gctgccaccc tgggctctgg tggaatggcc   1140
aggggaaggg agcctggggg agtcgggcac gtggtggccc aggtccagag tgtggatggc   1200
aatgcccagt gctgcgactg ccgggagcca gccccggagt gggccagcat caaccttggt   1260
gtcaccctct gcattcagtg ttccggcatc cacaggagcc ttggtgttca cttctccaaa   1320
gtccggtctc tgacccttga ctcatgggag ccagaactag tgaagctcat gtgtgagctg   1380
ggaaatgtca tcatcaacca gatctatgag gcccgcgtgg aggccatggc agtgaagaaa   1440
ccagggccca gctgctcccg gtgagcttgg ggtttagcct cccaggggaa tgggggaccc   1500
ctggagcaga agagggaaga ctgcctgctt ctccccttcc acaggcagga gaaggaggcc   1560
tggattcacg ctaaatacgt ggagaanaaa gttnctgacc aagcttgcct gagaattcga   1620
gggccaaaaa agtggcccgg gggcgcccaa gggggcaagc ctcctggtgc ccccaaagcc   1680
tttcattaag gccccgggcc aagggaagct tggaaatcca agccaggtat tagggnttgg   1740
gttgggncan ttcatttgag caat                                          1764

<210> 1384
<211> 1181
<212> DNA
<213> Homo sapiens

<400> 1384
ggctagacag actctcttgc ttggatggta ctccaccact ttcttggcac atgagatgca     60
agattgctca gggtgcagct aatggcatca attttctaca tgaaaatcat catattcata    120
gagatattaa aagtgcaaat atcttactgg atgaagcttt tactgctaaa atatctgact    180
ttggccttgc acgggcttct gasaagtttg cccagacagt satgactagc agaattgtgg    240
gaacaacagc ttatatggca ccagaagctt tgcgtkgaga aataacaccc aaatctgata    300
tttacagctt tggtgtggtt ttactagaaa taataactgg acttccagct gtggatgaac    360
accgtgaacc tcagttattg ctagatatta aagaagaaat tgaagatgaa gaaaagacaa    420
ttgaagatta tattgataaa aagatgaatg atgctgattc cacttcagtt gaagctatgt    480
actctgttgc tagtcaatgt ctgcatgaaa agaaaaataa gagaccagac attaagaagg    540
ttcaacagct gctgcaagag atgacagctt cttaaaactt tattggaaaa gactcttgac    600
tttttatata cacctatctc aaccattttt ttaactgatt tttttcctaa atattcttct    660
ttacctttaa caaggcatag gctgttgcag gacagtggtt attaaagcat gggttgaact    720
tccaaaatat aaaaatagag ccaccatatc aacacttagc cctacccatt agtatcaccc    780
ccagttctta cagtaatccc tgagaaatct ccttcaagca tcaccaaaca cagtttgaaa    840
attacagggt tagcaaaaag agcctgggct gtatgtaggg tggaaacact ctgatctgaa    900
gcccagctga ctccactact aatttgctgt aaagctttgg acatacactt agctgctgtg    960
agccactaat aacattgggc taatatctgc tgtgcttctc tgacaggtag tcatgaaaat   1020
caaatgatgc aaaatatata caagcacttt gtaaattgta aaatgataca aaatttaaag   1080
tttatagagc cagttacaaa atcctattag tcatatattt atagattgtg ttcacagcaa   1140
tcatttaacc acaaataaaa tatcccttga tgatactgcc a                       1181

<210> 1385
<211> 1615
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1589)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1603)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1604)
<223> n equals a,t,g, or c

<400> 1385
gcccacgcgt ccgctcgccg ctctagccct gcgccccagc ccggccgcgg cacctccgcc     60
tcgccgccgc taggtcggcc ggctccgccc ggctgccgcc taggatgaat atcatggact    120
tcaacgtgaa gaagctggcg gccgacgcag gcaccttcct cagtcgcgcc gtgcagttca    180
cagaagaaaa gcttggccag gctgagaaga cagaattgga tgctcactta gagaacctcc    240
ttagcaaagc tgaatgtacc aaaatatgga cagaaaaaat aatgaaacaa actgaagtgt    300
tattgcagcc aaatccaaat gccaggatag aagaatttgt ttatgagaaa ctggatagaa    360
aagctccaag tcgtataaac aacccagaac ttttgggaca atatatgatt gatgcaggga    420
ctgagtttgg cccaggaaca gcttatggta atgcccttat taaatgtgga gaaacccaaa    480
aaagaattgg aacagcagac agagaactga ttcaaacgtc agccttaaat tttcttactc    540
ctttaagaaa ctttatagaa ggagattaca aaacaattgc taaagaaagg aaactattgc    600
aaaataagag actggatttg gatgctgcaa aaacgagact aaaaaaggca aaagctgcag    660
aaactagaaa ttcatctgaa caggaattaa gaataactca aagtgaattt gatcgtcaag    720
cagagattac cagacttctg ctagagggaa tcagcagtac acatgcccat caccttcgct    780
gtctgaatga ctttgtagaa gcccagatga cttactatgc acagtgttac cagtatatgt    840
tggacctcca gaaacaactg ggaagttttc catccaatta tcttagtaac aacaatcaga    900
cttctgtgac acctgtacca tcagttttac caaatgcgat tggttcttct gccatggctt    960
caacaagtgg cctagtaatc acctctcctt ccaacctcag tgaccttaag gagtgtagtg   1020
gcagcagaaa ggccagggtt ctctatgatt atgatgcagc aaacagtact gaattatcac   1080
ttctggcaga tgaggtgatc actgtgttca gtgttgttgg aatggattca gactggctaa   1140
tgggggaaag gggaaaccag aagggcaagg tgccaattac ctacttagaa ctgctcaatt   1200
aagtaggtgg actatggaaa ggttgcccat catgactttg tatttatata caattaactc   1260
taaataaagc aggttaagta tcttccatgt taatgtgtta agagactgaa aataccagcc   1320
atcagaaact ggcctttctg ccaataaagt tgcatggtaa atatttcatt acagaattta   1380
tgttagagct ttcatgccaa gaatgttttc ttacaaaatt ctctttttat tgaggtttca   1440
ctaataagca gcttctactt ttgagcctca acttaaagca gaactgtttt ctactggatt   1500
tttcattaac agcaagcttt ttcttttatg taaaataaat ctattgtgaa ttgaaaaaaa   1560
aaaaaaaaaa atccgggggg gggccccgnc ccctttgggc ccnngggggg gggtt        1615

<210> 1386
<211> 4107
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (3861)
<223> n equals a,t,g, or c

<400> 1386
aattccgctt ccgtttggaa agccgcagcc tcagtcccgc cgccgcccgc tgcgtccgcc     60
cagcgccagc tccgcgtccc gaccggcccg cggcagcctg cgccgcgcca tggccacctc    120
cccgcagaag tcgccttctg tccccaagtc tcccactccc aagtcgcccc cgtcccgcaa    180
gaaagatgat tccttcttgg ggaaactcgg agggaccctg gcccggagga agaaagccaa    240
ggaggtgtcc gagctgcagg aggagggaat gaacgccatc aacctgcccc tcagcccaat    300
tccctttgag ctggaccccg aggacacgat gctggaggag aatgaggtgc gaacaatggt    360
ggatccaaac tcacgcagta cgcccaagct tcaagaactg atgaaggtat taattgactg    420
gattaatgat gtgttggttg gagaaagaat cattgtgaaa gacctagctg aagatttgta    480
tgatggacaa gtcctgcaga agcttttcga gaaactggag agtgagaagc taaatgtggc    540
tgaggtcacc cagtcagaga ttgctcagaa gcaaaaactg cagactgtcc tggagaagat    600
caatgaaacc ctgaaacttc ctcccaggag catcaagtgg aatgtggatt ctgttcatgc    660
caagagcctg gtggccatct tacacctgct cgttgctctg tctcagtatt tccgygcacc    720
aattcgactc ccagaccatg tttccatcca agtggttgtg gtccagaaac gagaaggaat    780
cctccagtct cggcaaatcc aagaggaaat aactggtaac acagaggctc tttccgggag    840
gcatgaacgt gatgcctttg acaccttgtt cgaccatgcc ccagacaagc tgaatgtggt    900
gaaaaagaca ctcatcactt tcgtgaacaa gcacctgaat aaactgaacc tggaggtcac    960
agaactggaa acccagtttg cagatggggt gtacctggtg ctgctcatgg ggctcctgga   1020
gggctacttt gtgcccctgc acagcttctt cctgaccccg gacagctttg aacagaaggt   1080
cttgaatgtc tcctttgcct ttgagctcat gcaagatgga gggttggaaa agccaaaacc   1140
gcggccagaa gacatagtca actgtgacct gaaatctaca ctacgagtgt tgtacaacct   1200
cttcaccaag taccgtaacg tggagtgagg ggctgccctg ggcccaccac tgcccaagag   1260
ttcttgctgt tggcgtactg gaccctcctc cgaactgcct taccctgctt attcctgtct   1320
cttgcactgt gctctcccac aagtccagct gcaacccaga gatagtggaa actgaaatta   1380
ggaaggaaat catcaataac tcagtgggct gacccatccc tcccaggcgc tggggaccaa   1440
cctagcaatg aaggttggga aggttgttcc cttcccggtg ccaggtccag atttccctcc   1500
atgatttggg aaccagstta ggcaaaagag tccccacaag atgaaaataa agatcctagt   1560
taccattcaa aggatgctaa ctgtgtgtca ggccccacac taagtgctct gctctgatat   1620
actcaaggcc attaatcttc aggactccca ttgacgtagg tgtttcattc cccttttaca   1680
gatgaggaaa ctaaggcttg gaggttaaat gacttgccag aagttggaat ttttttcctc   1740
tttgaacata acctctccct tctccctaaa ggtaaccact attctgagtc caatcatcaa   1800
ggttttgctt ttctttttag ctaagtatgc attcctcaat agtagacagt acaacatgtt   1860
tataacaagc caattacatt atgttctttg catgttctaa agttgtgtat gtgtgtgcac   1920
atctgagcac gtgcacatgt acacctgagc caaaaacacg agaacccact gatctcacca   1980
ctggggcaag ctaggtcaga gcttagtgat tcacactgaa attggcaaat tggatttaac   2040
ccaattaata gtgtgtgtgt ggcaggagtc atgtccctca catcctttgt acaaatgaaa   2100
attactctta attccttcag atttataata actctgtact ttggtttcag ggtgacattt   2160
gggaaggatt ttgtttagaa ttaatggagt ggcacatttt gcagcctttt tgcttgattg   2220
catgtaatgg aaatgcccta tattttcctg caaaataagt actaaattca ttatcgttaa   2280
gcaaatgtac aatatgctca ggcaccgcag agagctgggc acgggcccat gtgagcatca   2340
ctttggaagt agggctcttc aacagggacc cttgaacttt aaagaaagga acttcttttt   2400
gccttctaat tgatcattta gactattctg gctaagtctg cccacatgta attaccggct   2460
aattcaagcg aggaaaaatg taagtcattt agaccaaagc caagcagttt ctttgcgtgg   2520
gttactcaag ggcttgtggt tacttgtatc tcctctatgt gaacttgact ttgaaagaca   2580
gagctctagt gtgccagcct gctaagtcct gtaagaatag ggaagggcgg aggggggtgg   2640
gcagtgacta ggggacgaga agcatgggga aaatatttgc actctaaaca tacagagata   2700
gaggtggggc ttgtggtact taacacttgt agccatcaac tgactgagac cttgggctaa   2760
ataatcaatt gtgctgatat tacatctcgt tatggaatgt tcctaaatat gccaggtaga   2820
caccagccca agtaccctcc tccagaagtc tgtgactacc ttgtcactac tttaggccca   2880
ttccacaaag cccatctctg gtttgagaat tcattttgat ctgtatctac accacccaaa   2940
gttaggcctc ctataatgtc caaaacattc ctttcagcct ttttatttct tactgtactg   3000
tctcttactg tactgtctat ctgcagtaat tgaggaccca taaaatttag ataactacat   3060
gtctttgctc ttagaattgt cactcagcat aatgagcatt taacatacaa aggcaatgta   3120
ctgttttgtg ttgatctatg taaaagaata caattctttt ttacataatt agtgaaattt   3180
tattttttat taggaaacac taaatagtgt aatatttctt ttgcttttaa aaaaattcct   3240
ggtagcaaat caagataaat aattgcttca ttttcttgag caatactgaa gcaggatgaa   3300
gtaagaggaa tgcattcatt taaacatgct ttgctttatg aattttgtct cttttttggt   3360
ctctttttct tatattcaag ttacaaatgt acaagtatcc ttactaagag tgctcctttt   3420
gtattttaca tatatacagt atgaaaatac attggaacac taggaaagtt tttaaataac   3480
agttctaatt tatcagaaaa ttgtgttttg ggattgagtt ctttgtctca gcccagaatc   3540
ccaggtcctg ggcctggttt tctaatgctg tcatctcagt tcgatatttt actttagaay   3600
ctggaatctc ctacttaata tatgaccatg actttgaaag gcaaaagagg aatcaagaat   3660
aaataaaaca aacttaatct tcatctttaa aaaaaagaaa aaagaaacca aaatgagaat   3720
caacacttca taggctcact gggttttctt ttcttttctg ttaatttaaa ctcagttatt   3780
tttaatgctt aatacataca tggtgcaaaa tttaaaaagc gcaaataggt atctagtgga   3840
aaacctaagc ctccctctct nctccggcac ccattacctc tccctggagg caactgtttt   3900
gatccatttc ttacacacac tgccagagat actctaggca tgtaaagcac aaacatacat   3960
ataaaatctg cgggcttcaa aaaatataag taggatgtca tctatactgt catacacttt   4020
gttttttatc acttacttaa tgttatatct tggatattgt attaccctgg gtattaaaaa   4080
gaactccttt cacattttaa aataaaa                                       4107

<210> 1387
<211> 1460
<212> DNA
<213> Homo sapiens

<400> 1387
cgacccacgc gtccgggcag aaggatgact ctcagagatg accaacctgc aaagctagaa     60
aaggagccca agacgaggcc agaagagaac aagccagagc ggcccagcgg tcggaagcca    120
cggcccatgg gcatcattgc cgccaatgtg gaaaagcatt atgagactgg ccgggtcatt    180
ggggatggga actttgctgt cgtgaaggag tgcagacacc gcgagaccag gcaggcctat    240
gcgatgaaga tcattgacaa gtccagactc aagggcaagg aggacatggt ggacagtgag    300
atcttgatca tccagagcct ctctcacccc aacatcgtga aattgcatga agtctacgaa    360
acagacatgg aaatctacct gatcctggag tacgtgcagg gaggagacct ttttgacgcc    420
atcatagaaa gtktgaagtt cccggagccc gatgctgccc tcatgatcat ggacttatgc    480
aaagccctcg tccacatgca cgacaagagc attgtccacc gggacctcaa gccggaaaac    540
cttttggttc agcgaaatga ggacaaatct actaccttga aattggctga ttttggactt    600
gcaaagcatg tggtgagacc tatatttact gtgtgtggga ccccaactta cgtagctccc    660
gaaattcttt ctgagaaagg ttatggactg gaggtggaca tgtgggctgc tggcgtgatc    720
ctctatatcc tgctgtgtgg ctttccccca ttccgcagcc ctgagaggga ccaggacgag    780
ctctttaaca tcatccagct gggccacttt gagttcctcc ccccttactg ggacaatatc    840
tctgatgctg ctaaagatct ggtgagccgg ttgctggtgg tagaccccaa aaagcgctac    900
acagctcatc aggttcttca gcacccctgg atcgaaacag ctggcaagac caatacagtg    960
aaacgacaga agcaggtgtc ccccagcagc gagggtcact tccggagcca gcacaagagg   1020
gttgtggagc aggtatcata gtcaccacct tgggaatctg tccagccccc agttctgctc   1080
aagggrcmgr gaaaaggrtw gkaagtttga grgaaaaacm atgkaaagrg gcttcttcac   1140
ataattggtg aatcagaggg agagacactg agtatatttt waagcmtatt aaaaaaatta   1200
agtcaatgtt aaatgtcaca acatattttt agatttgtat atttaaagcc tttaatacat   1260
ttttgggggg taagcattgt catcagtgag gaattttggt aataatgatg tgttttgctt   1320
cccctttgta accaagttta ttctgtacta caggagtggt gcttaccagg gtctaaactc   1380
cccctgtgag attaataagg tgcattgtgg tctttctgtg ttaataaaat gtgctctgaa   1440
taacaaaaaa aaaaaaaaaa                                               1460

<210> 1388
<211> 1361
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1346)
<223> n equals a,t,g, or c

<400> 1388
gctatcgatg agtacatgaa gctcgtggca caggattacc tccaggagac cctgggtgag     60
ctgggggaga gtccatgtca gcggcctgct ggtgagctag gggacctggg tgaagttcta    120
agagtccttg agcaacctgg attctggtag tgastggtgt tttgggggtg ctaggatcct    180
ggggacaatt gggagctccc caagatgttg ggtgcctccg gaataacctg aagacaaggt    240
tggaggatgg gtgtggcagg ttttggtggt catggcccca gcccctatct ggctgtgctg    300
ggctgcagga caggttgtgc ggcgtctctg tgcttctact gaggactgtg aagtggaccc    360
cagcaaatgt ccagcctcgg agctgccaga gcaccaggcc agacttcgga acagctgcga    420
ggagyctccc cgtctgacca ttcattgcct cttctgcacc agctggttcc ctgcggagct    480
gggcatcgtg ttctcaagct ggcgagaagc atgtaaagaa cgtggctctg aggtgctggg    540
cccccgactg gtgtgcgcct ccctcttcct gcggctcctg tgccctgcca tcctggcacc    600
cagcctcttt ggtttggcac cagaccatcc agcacccggc ccagcccgca ccctcacact    660
gattgccaag gtcatccaga acctcgccaa ccgtgccccg ttcggtgaga aggaggccta    720
catgggcttc atgaatagct tcctggrgga acatggacca gccatgcaat gcttcctgga    780
ccaggtagcc atggtggatg tggatgctgc ccccagtggt taccagggca gtggtgatct    840
ggccctccag ttagctgtcc tgcatgccca gctctgtaca atttttgctg agcttgacca    900
gacaacccga gacaccctgg aaccactgcc caccatcctg cgagccattg aggagggcca    960
gcctgtgctt gtgtcagtgc caatgcgtct cccactgccc ccggcccagg tccactccag   1020
cctctccgca gggagaagcc cggcttcctg gccccccggg acctccccaa gcacacccct   1080
ctcatctcca agagccagtc tctgcgcagt ttcgccgctc agagagttgg gcccggccac   1140
ggccggacga agagcggccc ctgcggcggc cccggccggt gcagcgcacg cagagtgtcc   1200
cggtccggcg tcctgcccgc cgccgccaat ctgcggggcc ctggccgcga cccaaaggct   1260
ccctgagcat gggaccagcg ccccgsgccc ggccttggac ccgggamtcc gcttcgctgc   1320
ttcggaagcg tcggtaacct tggcancgcc aaattggaac a                       1361

<210> 1389
<211> 897
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (497)
<223> n equals a,t,g, or c

<400> 1389
cgcgtgcgcc caggycaggy ggagggactg ccccgccctg gtccagtgat tgatcagcag     60
tgattactga ggctttaatg gtccgcttgg atgggaatta attctgggat ggataaataa    120
tgcatcgagg tttatgtagt ccaaggcgag ccgtccgtcc ggagccagga gaggtagccg    180
agggagcctg acgggtgacg ccagcggcca cggggccccg aacgagcagg acatgagggg    240
cgactaggcg cgaggacgag caaaagcaag tggatgacag catgaacggc cctgcggggc    300
tggccggacg gctgcaagaa catgctgagc ccaaagwtca ggcasgccag garggcccgc    360
tccaaaagcc tagtgatggg ggagcagarc cggagccctg ggcggatgcc gtgccctcac    420
asgctgggcc ccgtgctgaa ggcgggctgg ctgaagaagc agaggagcat catgaagaac    480
tggcagcagc gctggtnttg tgctgcgtgg ggatcagctt ttytactaca aggmcaaaga    540
tgagatcaag ccccaggaga ataagtgagg gaagctcagc aataaggagc catagaagat    600
tgatttaaag tttgatgtga ttgagtaaaa gcttgagact ggtggggaga aagtcaagat    660
ggatgggaaa gcacatgcac ttctaggagt ggaacattaa tattggacag tcggaaacca    720
gaaatcttta agaaagagga aacctcaggg gaagaaagag aggccatcct atcccataac    780
ttgaaagtca caggaatatt tcagcctgca gggaatcttc atttcccagc ccattgttta    840
ccaaacttgc acgtcaaaaa caaaaacaaa aaataaaatg ttgctttcat gaaaaaa       897

<210> 1390
<211> 717
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (716)
<223> n equals a,t,g, or c

<400> 1390
ggcagaagct tacggagctg ntttcgggac ctggtgggca tagagaacct cattgctcct     60
ggcagggagt tcatccgtga gggctgcctt cacaagctca ccaagaaggg cctgcagcag    120
aggatgtttt ttctgttctc agatatgttg ctgtacacaa gcaaaggagt tgcagggacc    180
agccacttcc ggatccgggg cctccttccc ctccaaggca tgctggtgga agaaagtgat    240
aacgagtggt ctgttccaca ctgtttcacc atctacgcgg ctcagaaaac aatcgtggtg    300
gcagccagca ctcggctgga gaaagagaag tggatgctgg acctgaactc cgcgatccaa    360
gcagccaaga gtggcggtga cacggcccct gcactgccag gccgcactgt gkcactcgtc    420
cccccagatc ccccaacgag gkatctctgg agcaggagtc agaagatgat gctcggggtg    480
tccgcagctc cctggagggg catggcagca ccgggccaac accacaatgc acgtgtgctg    540
ggtaccggaa caccagcgtg tccagggcaa gaccacagtg cagctgtcga gaaccaagct    600
ttcaggatat ctgctaagaa agttcaaaaa caagtcatgg gctggcagaa gctctgggtc    660
gtctttacca acttctgttt tgttcttctt acaaaactca tcagggatga ctaccnc       717

<210> 1391
<211> 465
<212> DNA
<213> Homo sapiens

<400> 1391
ggcagagctc atagcttgtt ggttacctcc atggggcaca taaagctgac agattttgga     60
ttatctaagg tgggactaat gagcatgact accaaccttt acgagggtca tattgagaag    120
gatgctagag agttcctgga taaacaggtc tgtggcacac ctgaatacat tgcaccagaa    180
gtgattctga ggcagggtta tggaaagccg gtggactggt gggccatggg gattatcctc    240
tatgaatttc tggttggatg cgtgccattc tttggggata ctccagaggg ctatttggac    300
aagtcatcag tgatgagatc aactggcctg agaaggatga ggcaccccac ctgatgccag    360
gatctgatta ccttactcct caggcagaat ccctggagag gctgggacag gtggtgcata    420
twaagtaaac agcatcgatt ttccgttctt tagctggaca gtttc                    465

<210> 1392
<211> 867
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (77)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (812)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (831)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (855)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (862)
<223> n equals a,t,g, or c

<400> 1392
ggccaccgca caaatggaag agcgactagc agagtttatt tcctccaaca ctccagacag     60
cgtgctgccc ttggcanatg gagccctgag ctttattcat catcaggtga ttgagatggc    120
ccgagactgc ctggataaat ctcggagtgg cctcattaca tcacaatact tctacgaact    180
tcaagagaat ttggagaaac ttttacaaga tgctcatgag cgctcagaga gctcagaagt    240
ggcttttgtg atgcagctgg tgaaaaagct gatgattatc attgcccgcc cagcacgtct    300
cctggaatgc ctggagtttg accctgaaka gttctaccac cytttagaag cagctgaggg    360
ccacgccaaa gagggacaag ggattaaatg tgacattccc cgctacatcg ttagccagct    420
gggcctcacc cgggatcccc tagaagaaat ggcccagttg agcagctgtg acagtcctga    480
cactccagag acagatgatt ctattgaggg ccatggggca tctctgccat ctaaaaagac    540
accctctgaa gaggacttcg agaccattaa gctcatcagc aatggcgcct atggggctgt    600
atttctggtg cggcacaagt ccacccggca gcgctttgcc atgaagaaga tcaacaagca    660
gaacctgatc ctacggaacc agatccagca ggccttcgtg gagcgtgaca tactgacttt    720
cgctgagaac ccctttgtgg tcagcatgtt ctgctccttt gataccaagc gccaattgtg    780
catggtgatg gagttacgtt gaagggggag angtgccact ctgctgaaga naattggggc    840
ctgctgttga aatgngggtt anatttg                                        867

<210> 1393
<211> 613
<212> DNA
<213> Homo sapiens

<400> 1393
gatgagctga gcttcaaggc tggggatgag ctgaccaaga tggaggacga ggatgagcag     60
ggctggtgca aggaacgctt ggacaacggg caaattatgt ggaggcgatc cagtgatgag    120
tcggggacag gccagcgggg ggacggaggc ggcgggccca ggagcctcag ccagccacgt    180
gggcatccac tccttttcct gcaagagatg atggttccat tgctcttggc ttcatggtgt    240
tcctggaagg cagatgagct ggtcatttcg cctgggactc ggcaccttty cgagtgcagc    300
tggagggatc tgagcgcagg aagacgcaga acaacagaaw tagccgcccc tccccgccca    360
ctgtcctgtt ggcctatcat agatctctat gttcttgact ttgtctctcc tttccgagtc    420
aatggtggtt tacacctaat cctggttcca ctgataactc ttctccggaa cggagtccat    480
tcaacctggc aacctaaatg gacaaggtta acattcccaa tttggaatga aggaatttgg    540
aggttttttt tttaaagggc ttgtgttaca atttattact tttttattac acctgttcat    600
ttctacttaa att                                                       613

<210> 1394
<211> 2107
<212> DNA
<213> Homo sapiens

<400> 1394
gggctcagga tgagtgtgga tggcatgaac tcacactagc actggctcca cctgtgctcc     60
ttcggaagga gccctcagcc ctgagcccca aggctccagt gccctcccct tgcggggcgg    120
gggcctcaca ccctctgccg ccctgtgctg agggccctgt ggcctcccct ttcttgcagt    180
gtgagcagct acgagaagac ccagagctat cccaccgact ggtcagacga tgagtctaac    240
aaccccttct cctccacgga tgccaatggg gactcgaatc cattcgacga cgacgccacc    300
tcggggacgg aagtgcgagt ccgggccctg tatgactatg aggggcagga gcatgatgag    360
ctgagcttca aggctgggga tgagctgacc aagatggagg acgaggatga gcagggctgg    420
tgcaagggac gcttggacaa cgggcaagtt ggcctatacc cggcaaatta tgtggaggcg    480
atccagtgat gagtcgggga caggccagcg gggggacgga ggcggcgggc ccaggagcct    540
cagccagcca cgtgggcatc cactcctttt cctgcaagag atgatggttc cattgctctt    600
ggcttcatgg tgttcctgga aggcagatga gctggtcatt tcgcctggga ctcggcacct    660
ttccgagtgc agctggaggg atctgagcgc aggaagacgc agaacaacag aaatagccgc    720
ccctccccgc ccactgtgcc tgttggccta tcatagatct ctatgttctt gactttgtct    780
ctcctttccg agtcaatggt gggttacact gatcttgttc cactgattac tctctctgac    840
gagtccatca cctgcaactt aaatgaacaa gcttacatcc cattttgagt gaagattttg    900
aggtttttaa tttaaaggct gtgtacagtt atactttttt atacacctgt tcatttctac    960
ttaaattatg gcacagattg atgcgcacca gtcttgagga aacgatctcc ctattccctt   1020
accctgttac tcagccacgc cgtgtgtagg cttagcctca ggtggcagat gtttgaggaa   1080
aggaattatg ccaggaaggt gggaccgggt tatggtcggg tttctattgg gaatgctctt   1140
tgtgcttttg ggcatctgaa tggaagcttt acatagaacc ttaggtagaa ctcccccaaa   1200
tcgccatatt taaaaattat tttcactcta ttcttgctta aaactgtact cttttgcaaa   1260
ttaacaattt tatcactgat tcagagttaa aaagaagact aacttttcaa gcaaatgcat   1320
ctgtaaagat gctttagatt agactgtcat gtctcagtgt ctatctgtat atattatttg   1380
atattcagag aatctaaagc actcgtctac tgttttaatg agatttaaca gcttttaaca   1440
gtgagtttcg tttgtaaact gcttgaagtc tgtggcattc aggcacacrt ctggctggcc   1500
ggctgggtct cctcccgggc tcagtgggcc tggggctctc tgacgtggtg cctgctggag   1560
ggaggctcgt cgtcaccagc tgactgctgg tccggcttct gaccggcctt tgtcctggct   1620
ccgtagcaga acactgtaaa agtgcccgcg tctttgcagt agttgcagat ttcagtcgtc   1680
gtgttacttg tgcacaaaca gaagctgggt cttacccgca gcacgagtgt ctcgggctgc   1740
ccggagtcgc ccgggagcag gtgctgcagc cagagttacg cgggggccac gcgggccggc   1800
gggggtgggg ggaacgtggg ggaacctgtg tttcacgtga ctcagcagtg cccgccgccg   1860
tcaccagcta tgcattcact ccgtttccag tgagcagatg tcttgcttgg aaagtggacc   1920
tgtgtctgtg tctgtcctga gaacttacca gcagaaatcc tcatttctgt gctacggatt   1980
taccaaaaat tgtcaagtct ttttcagttt aacagttcct ttamatgtgt agtatttgag   2040
gaaaaaaatc aataaacagt tgatctcgtg caaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2100
aaaaaaa                                                             2107

<210> 1395
<211> 1184
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (633)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1102)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1120)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1127)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1141)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1164)
<223> n equals a,t,g, or c

<400> 1395
gttcccctgt cttccccaac gccccggagc cgccggccgc tagcgtcagc gccagccaga     60
attaaggaag ttcactggag taaaatggag gcctcagtaa tattacccat tctgaagaaa    120
aaactagcct tcctttcagg aggaaaggac agacggagtg gcctcatttt gacaattcca    180
ttatgcctcg aacagacaaa tatggatgag ctgagtgtca ccttagacta cctactcagc    240
attccaagtg agaagtgtaa ggctagagga tttaccgtga ttgtggatgg cagaaaatca    300
cagtggaatg tggtgaaaac agtagtcgta atgctacaga atgttgttcc agctgaggtg    360
tcccttgttt gtgtggtaaa gccagatgaa ttctgggata agaaagtaac gcatttttgt    420
ttttggaagg agaaggatag acttggcttt gaggttattt tagtgtccgc caacaaattg    480
actcgttata tagaaccatg ccaattaaca gaagattttg gtgggagtct cacctatgat    540
cacatggact ggttaaataa gaggctggtt tttgagaagt ttacaaagga atctacatsa    600
ttattagatg aacttgcttt gattaacaat ggnaagtgca twaaggaaat cagcaagaga    660
aagaaaggtc tgtggattta aactttcttc catcggttga tcctgaaaca gttcttcaga    720
cagggcatga attgttgtcc gaattacagc agcgtcgatt taatggctca gacggagggg    780
tttcatggtc tcctatggat gatgaacttc ttgcacagcc acaggttatg aaattattag    840
attcactccg agagcaatat acccgctacc aggaaagttt gtaggcaacg takcaagcgc    900
acacagttag aagagattca acagaaggta atgcaggtgg ttgaactggc tagaagggcc    960
tggatcagaa caacttaaga gccccagtgg ggcatttgga gactccatta gggcctccca   1020
ggccttacag cagaaacacg aagagatttg agagccagca cagtgaatgg tttgcagtgt   1080
aatgttggac ctttatccag cnatttgcag cactccttgn atgcctngcg aattaaggaa   1140
natctttgtt ggacctaaag ttcncttgcg gcaacacttt gggg                    1184

<210> 1396
<211> 839
<212> DNA
<213> Homo sapiens

<400> 1396
tatacgaaag ctgagaaatt caaaagcttt caacattcaa gattatatca gcaatttaat     60
gaaaataatt ctattgggga gacacaagcc cgaaaacttt caaaattgcg agtccatgag    120
tttatttttc acaccaggaa gttcattacc agaatatatc ccaaagcaac aagagcagac    180
tcttctaatt ttaatcccca agaattttgg aatataggtt gtcaaatggt ggctttaaat    240
ttccagaccc ctggtctgcc catggatctg caaaatggga aatttttgga taatggtggt    300
tctggatata ttttgaaacc acatttctta agagagagta aatcatactt taacccaagt    360
aacataaaag agggtatgcc aattacactt acaataaggc tcatcagtgg tatccagttg    420
cctcttactc attcatcatc taacaaaggt gattcattag taattataga agtttttggt    480
gttccaaatg atcaaatgaa gcagcagact cgtgtaatta aaaaaaatgc ttttagtcca    540
agatggaatg aaacattcac atttattatt catgtcccag aattggcatt gatacgtttt    600
gttgttgaag gtcaaggttt aatagcagga aatgaatttc ttgggcaata tactttgcca    660
cttctatgca tgaacaaagg ttatcgtcgt attcctctgt tttccagaat gggtgagagc    720
cttgagcctg cttcactgtt tgtttatgtt tggtacgtca gataacagct aatgataaat    780
gacatatcat tagctatgca tcgcaataaa acagccaaaa tgaaaaaaaa aaataaaaa     839

<210> 1397
<211> 1017
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (79)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (126)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (128)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1014)
<223> n equals a,t,g, or c

<400> 1397
ggcgtgctng ccagctacca tacggtgtct ttacagttgc tagacctgat gcacaccctg     60
cacacgcggg cagcctctnt ctacagctca tgggcggagg agcaacgcca cctggagaca    120
ggtgcnanga agattgaagc tgattctcgc accctctggg cccactgctg gtgcccttta    180
ctgcagggta ttgcctgcct gtgctgcgat gcccggcgcc aggtacggat gcaggcactg    240
acctatctgc agcgagcact acttgtacat gatctgcaaa agctagatgc cctggaatgg    300
gagtcctgtt ttaacaaggt gctgtttcct ctacttacca agctcttgga gaacatcagc    360
cctgcagatg tgggtgggat ggaggagacc cggatgaggg cttccacatt gctctctaag    420
gtcttcctgc agcacctgtc tccactgctg tcactctcta cctttgcggc cctctggctc    480
accatcttgg acttcatgga caagtacatg cacgcaggct ccagcgactt actgtcagag    540
gcgatccctg agtctctgaa gaacatgctt ctggtgatgg acacagcgga gattttccac    600
agtgcagatg cacggggagg cggcccctcg gccctctggg agatcacctg ggaacgcatt    660
gactgttttc tccctcacct acgagatgaa ctcttcaagc agaccgtcat ccaggacccc    720
atgcccatgg agcctcaagg ccaaaagcct ctcgcctcag cccacctgac ttccgctgct    780
ggcgacacta ggacacctgg ccatccaccg cccccagaga ttccatctga gctgggggcc    840
tgtgactttg agaagcccga gagcccccga gccgccagca gcagctcccc aggatcacca    900
gtggcctcaa gccccagcag gctgagcccc amccccgamg gcctccamcc ttggctcarc    960
ccccactgat ctgcagccct tggstcccca atgcagtggg cgtgccaact atgnctt      1017

<210> 1398
<211> 2170
<212> DNA
<213> Homo sapiens

<400> 1398
tttttttttt tttttttaaa agtaaacaaa tctactttta ttcagaaatg atgcttttta     60
agtaagggta ggaaatcttc attttcttta ataactaact ctttttccct cttcctaatt    120
taattcaatt tttacagacc ccctattgat aaagatgtaa gatctgctat tcattgtctt    180
tcttatacat agaagtaaaa tcacagaaat aattattatt ttatgggagg ataaaacatt    240
tatttaaatg gaaacactaa tctttatttt catcatgctg aagtgtgtgg ttacaatttc    300
caataaaaca ctatatataa taagcaaaat aagttagtac attgtaaact tatgcacagt    360
ttcatcaatt aacagtttaa gaacaaacaa gccatttaag actttggagc tacatttagt    420
aaaaaattgc aaacactcaa atcttatcaa ccccaagtaa gacagtaaag agctattcaa    480
gacttcttca aaccaattac acaaatacat gtttattttt ggttacagtc ccctgctatg    540
cacaagacca ttggaatgct ggaacaatta cacattttaa aacggcaaaa agcaaagcaa    600
ggagataaca tgccagcctt agagaagctg tcttgaaagt gcaaactgcg ttttctcttc    660
ctgaaccact aggataagaa cgggtacctc agacgacacg gcagggtcat gagcatgctt    720
tctatacccc actggtggga catttactgg aaccaggtct ccatgccttt gaagatacct    780
ccggttttaa acagtgaaca ggcttcaact aaatatagtg caaatcaaat accaaggagc    840
aaaacgacag aatagagact gtcacagatg attgacttcc tgtttctcta cctggcacaa    900
cccacatggg acacattggc acacggtaac aacaacttct atttaggttt tgatacggaa    960
ggcggtgcgg cggagcgaat gcagggcaac cacgcaacag cccctgagca aggccccgat   1020
gttatacaca ggatccgttc cccctctctg agtactgaat gcccacagaa mcstggggac   1080
cacgggggca gccacagcca ggagatccac caggaagctg ctgctccagt actgcctcac   1140
racgcccccg cgagccagtg ggatgacacc atccaacctc tcttccacgc aggctgcaaa   1200
atccagctct ctcatgaggc ggtttgcatg aacttctgca tccacattgg cgtagggggt   1260
ctccacggga gacaaaagga tggctgagtt tggatttctt ggagttaaat caaccactaa   1320
ggcagagagg gactctggga agctctccat cgagtctggt tcagactcat caggggacgc   1380
caagctcgag ggacaggggt cctggagctt ctgcagcaca ctctgaatga gctctgagat   1440
ggctgggctg tagggcacca cgtcggtctg aacggctcgc tccaccacca cactgccctc   1500
ctcctgaccc atgactatgg gcagcagctc caggacgtta gccccagggg tggaatgcac   1560
aagctccagg tcaccagatt ctgtggtggt ggctgtcact atctcatcga acaaatctgt   1620
gctgttggct atgctatctc ctaccagtag ctccctgtca gccccttccc ccgtgacctg   1680
ctcttccaga gataacccat ctgccattgt gtcaagaggg gggttgaggg ttaagctctt   1740
ctctggggaa tcacatggaa agtctaggca cagttcgtcc ctcagagagc cactgtgtgc   1800
catctccatg ctctgaagga gagactccag cttcttgttt tggatgttta tgtccacaaa   1860
atatttctga atgcctttat ctttatcagc caagctgctc cgcatggttt cgatgacctg   1920
tttgagctgt ttaatctctt tcctggcttc tttgagtgcc aactgggcct ctacccggtg   1980
acactcctcc tcaatccagt cctctcgcat gcgggccagc tgggacttaa gctccacgat   2040
ttcactttcc ctagagtgcc aagacaagca tggttaatta aaaaaaaara aaaaaaaaaa   2100
ctcgagagta cttctagagc ggccgcgggc ccatcgattt tccacccggg tggggtacca   2160
ggtaagtgta                                                          2170

<210> 1399
<211> 631
<212> DNA
<213> Homo sapiens

<400> 1399
cctactaaag ggaacaaaag ctggagctcc ccgcggtggc ggccgctcta gaactagtgg     60
atcccccggg ctgcaggaat tcggcacgag ggagcatgga gcgcttggca gccttgggga    120
acatgcagcg aaagttgtgg gaaaggtact cagacaagag caagactttg taataaccca    180
ccaccagcgt ttggtgggtc ctactgtgat ggagcagaaa cacagatgca agtttgcaat    240
gaaagaaatt gtccaattca tggcaagtgg gcgacttggg ccagttggag tgcctgttct    300
gtgtcatgtg gaggaggtgc cagacagaga acaaggggct gctccgaccc tgtgccccag    360
tatggaggaa ggaaatgcga agggagtgat gtccagagtg atttttgcaa cagtgaccct    420
tgcccaaccc atggtaactg gagtccttgg agtggctggg gaacatgcag ccggacgtgt    480
aacggagggc agatgcggcg gtaccgcaca tgtgataacc ctcctccctc caatggggga    540
agagcttgtg ggggaccaga ctcccagatc cagaggtgca acactgacat gtgtcctgtg    600
gatggaagtt ggggaagctg gcatagtgga g                                   631

<210> 1400
<211> 1644
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1138)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1636)
<223> n equals a,t,g, or c

<400> 1400
cgacccacgc gtccgggaca gcagggctcc gggcaaggag gtctggatgc tgagggcggt     60
ccctgagggg cgggcggggc ccgaccggcg ctctgtgtgg ccgaggccat gaagccgcag    120
ccgcccggct aggccccggg cggctctagc ccagggcggc ccgcggggcg ctgggcctgg    180
ctcccggctc cggtttccgg gccggcgggt ggccgctcac catgcccggc aagcaccagc    240
atttccagga acctgaggtc ggctgctgcg ggaaatactt cctgtttggc ttcaacattg    300
tcttctgggt gctgggagcc ctgttcctgg ctatcggcct ctgggcctgg ggtgagaagg    360
gcgttctctc gaacatctya gcgctgacag atctgggagg ccttgamccc gtgtggctgt    420
ttgtggtagt tggaggcgtc atgtcggtgc tgggctttgc tggctgcatt ggggccctcc    480
gggagaacac cttcctgctc aagtttttct ccgtgttcct cggtctcatc ttcttcctgg    540
agctggcaac agggatcctg gcctttgtct tcaaggactg gattcgagac cagctcaacc    600
tcttcatcaa caacaacgtc aaggcctacc gggacgacat tgacctccag aacctcattg    660
actttgctca ggaatactgg tcttgctgcg gagcccgagg ccccaatgac tggaacctca    720
atatctactt caactgcact gacttgaacc ccagccggga gcgctgcggg gtgcccttct    780
cctgctgcgt cagggaccct gcggaggatg tcctcaacac ccagtgtggc tacgacgtcc    840
ggctcaaact ggagctggag cagcagggct tcatccacac caaaggctgc gtgggccagt    900
ttgagaagtg gctgcaggac aacctgattg tggtggcggg agtcttcatg ggcatcgccc    960
tcctccagat ctttggcatc tgcctggccc agaacctcgt gagtgacatc aaggcagtga   1020
aagccaactg gagcaaatgg aatgatgact ttgaaaacca ctggcttacg cccaccattt   1080
ccgaggtcct gtccacggcg gggcctcagc agaactctct gactggggcc cctggccngg   1140
ccccacccag ccgacatgtt ttctttggcc tgggtggttt ataccctgag ccaaccttta   1200
aaaattggta gatttcacat aaaagtccag atccacagct tctcttgaag aatgaccacc   1260
tggctacgcg gctcttcggt ggcaacacta cctgggacac tgcctcccca gtcaccaagg   1320
gccccagctg gcccgttcta ctcacctaag tgccgcctga cccttgtaca ctaggagctg   1380
gcctcccacc tctgcagggt tatttcctgc acctcgaggc cgctgcgggc caatctggag   1440
tgaaacacgg ggacctgaag gatggagagg ctggaccccg ctttgaagag ggtgcagcct   1500
gggaagggcg gccttgctgg ggactgcggt gggagtagag tkcccaggar arggtctgag   1560
gggtkggatt gggggkcagg acaatttttg caaaagaagt agcttggagg ccatgggact   1620
ggcgggagct gttttngggg gatt                                          1644

<210> 1401
<211> 2867
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (2825)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2845)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2850)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2858)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (2866)
<223> n equals a,t,g, or c

<400> 1401
tcgcagcagg gtgtgtccag atggtcagtc tctggtggct agcctgtcct gacaggggag     60
agttaagctc ccgytctcca ccgtgccggc tggccaggtg ggctgagggt gaccgagaga    120
ccagaacctg cttgctggag cttagtgctc agagctgggg agggaggttc cgccgctcct    180
ctgctgtcag cgccggcagc ccctcccggc ttcacttcct cccgcagccc ctgctactga    240
gaagctccgg gatcccagca gccgccacgc cctggcctca gcctgcgggg ctccagtcag    300
gccaacaccg acgcgcagct gggaggaaga caggaccctt gacatctcca tctgcacaga    360
ggtcctggct ggaccgagca gcctcctcct cctaggatga cctcaccctc cagctctcca    420
gttttcaggt tggagacatt agatggaggc caagaagatg gctctgaggc ggacagagga    480
aagctggatt ttgggagcgg gctgcctccc atggagtcac agttccaggg cgaggaccgg    540
aaattcgccc ctcagataag agtcaacctc aactaccgaa agggaacagg tgccagtcag    600
ccggatccaa accgatttga ccgagatcgg ctcttcaatg cggtctcccg gggtgtcccc    660
gaggatctgg ctggacttcc agagtacctg agcaagacca gcaagtacct caccgactcg    720
gaatacacag agggctccac aggtaagacg tgcctgatga aggctgtgct gaaccttaag    780
gacggggtca atgcctgcat tctgccactg ctgcagatcg acmgggactc tggcaatcct    840
cagcccctgg taaatgccca gtgcacagat gactattacc gaggccacag cgctctgcac    900
atcgccattg agaagaggag tctgcagtgt gtgaagctcc tggtggagaa tggggccaat    960
gtgcatgccc gggyctgcgg cgcttcttcc agaagggcca agggacttgc ttttatttcg   1020
gtgagctacc cctctctttg gccgcttgca ccaagcagtg ggatgtggta agctacctcc   1080
tggagaaccc acaccagccc gccagcctgc aggccactga ctcccagggc aacacagtcc   1140
tgcatgccct agtgatgatc tcggacaact cagctgagaa cattgcactg gtgaccagca   1200
tgtatgatgg gctcctccaa gctggggccc gcctctgccc taccgtgcag cttgaggaca   1260
tccgcaacct gcaggatctc acgcctctga agctggccgc caaggagggc aagatcgaga   1320
ttttcaggca catcctgcag cgggagtttt caggactgag ccacctttcc cgaaagttca   1380
ccgagtggtg ctatgggcct gtccgggtgt cgctgtatga cctggcttct gtggacagct   1440
gtgaggagaa ctcagtgctg gagatcattg cctttcattg caagagcccg caccgacacc   1500
gaatggtcgt tttggagccc ctgaacaaac tgctgcaggc gaaatgggat ctgctcatcc   1560
ccaagttctt cttaaacttc ctgtgtaatc tgatctacat gttcatcttc accgctgttg   1620
cctaccatca gcctaccctg aagaagcagg ccgcccctca cctgaaagcg gaggttggaa   1680
actccatgct gctgacgggc cacatcctta tcctgctagg ggggatctac ctcctcgtgg   1740
gccagctgtg gtacttctgg cggcgccacg tgttcatctg gatctcgttc atagacagct   1800
actttgaaat cctcttcctg ttccaggccc tgctcacagt ggtgtcccag gtgctgtgtt   1860
tcctggccat cgagtggtac ctgcccctgc ttgtgtctgc gctggtgctg ggctggctga   1920
acctgcttta ctatacacgt ggcttccagc acacaggcat ctacagtgtc atgatccaga   1980
aggtcatcct gcgggacctg ctgcgcttcc ttctgatcta cttagtcttc cttttcggct   2040
tcgctgtagc cctggtgagc ctgagccagg aggcttggcg ccccgaagct cctacaggcc   2100
ccaatgccac agagtcagtg cagcccatgg agggacagga ggacgagggc aacggggccc   2160
agtacagggg tatcctggaa gcctccttgg agctcttcaa attcaccatc ggcatgggcg   2220
agctggcctt ccaggagcag ctgcacttcc gcggcatggt gctgctgctg ctgctggcct   2280
acgtgctgct cacctacatc ctgctgctca acatgctcat cgccctcatg agcgagaccg   2340
tcaacagtgt cgccactgac agctggagca tctggaagct gcagaaagcc atctctgtcc   2400
tggagatgga gaatggctat tggtggtgca ggaagaagca gcgggcaggt gtgatgctga   2460
ccgttggcac taagccagat ggcagcccsg atgagcgctg gtgcttcagg gtggaggagg   2520
tgaactgggc ttcatgggag cagacgctgc ctacgctgtg tgaggacccg tcaggggcag   2580
gtgtccctcg aactctcgag aaccctgtcc tggcttcccc tcccaaggag gatgaggatg   2640
gtgcctctga ggaaaactat gtgcccgtcc agctcctcca gtccaactga tggcccagat   2700
gcagcaggag gccagaggac agagcagagg atctttccaa ccacatctgc tggctctggg   2760
gtcccagtga attctggtgg caaatatata ttttcactaa ctaaaaaaaa aaaaaaaaaa   2820
ctcgnggggg ggcccggaac ccagntcggn gtaatccnat tagacnt                 2867

<210> 1402
<211> 813
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (779)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (809)
<223> n equals a,t,g, or c

<400> 1402
gatcccattc ttctctcggt gggaatgctt gtggggggaa aaagaaacgc aatagataaa     60
gcggggcgca tgcgctcccg gcacaggctt cgattgtrag gaargccggc tagtctccga    120
gctcatcccg ccttgcgcat gcggagaagg taaaccagcg ccccgagttg aggcgcgggt    180
ttggtggcgc gtttcagcga agtcgcacgt gaaggatagc agtggcctga gaaagaccca    240
gtcatggcag cctccagcat cagttcacca tggggaaagc atgtgttcaa agccattctg    300
atggtcctag tggcccttat cctcctccac tcagcattgg cccagtcccg tcgagacttt    360
gcaccaccag gccaacagaa gagagaagcc ccagttgatg tcttgaccca gataggtcga    420
tctgtgcgag ggacactgga tgcctggatt gggccagaga ccatgcacct ggtgtcagag    480
tcttcgtccc aagtgttgtg ggccatctca tcagccattt ctgtggcctt ctttgctctg    540
tctgggatcg ccgcacagct gctgaatgcc ttgggactag ctggtgatta cctcgcccag    600
ggcctgaagc tcagccctgg ccaggtccag accttcctgc tgtggggagc aggggccctg    660
gtcgtctact ggctgctgtc tctgctcctc ggcttggtct tggccttgct ggggcggatc    720
ctgtggggcc tgaagcttgt catcttcctg gccggcttcg tggccctgat gaggtcggng    780
cccgaccctt ccacccggcc ctgctactnc tgg                                 813

<210> 1403
<211> 552
<212> DNA
<213> Homo sapiens

<400> 1403
tatgttcacc ctggacgtgg aggagaatga gaatggggag cgcaccccct acctaattgt     60
catgggtgct ttggacaggg aaacccagga ccagtatgtg agcatcatca tagctgagga    120
tggtgggtct ccacactttt gggcagtgca ctctcaccat tggcatcagt gacattaatg    180
acaattgccc tctcttcaca gactcacaaa tcaatgtsac tgtgtatggg aatgctacag    240
tgggcacccc aattgcagct gtccaggctg tggataaaga cttggggacc aatgctcaaa    300
ttacttattc ttacagtcag aaagttccac aagcatctaa ggatttattt casctggatg    360
aaaacactgg agtcattaaa cttttcagta agattggagg aagtgttctg gagtcccaca    420
agctcaccat ccttgctaat ggaccaggct gcatccctgc tgtaatcact gctcttgtgt    480
ccattattaa agttattttc agaccccctg aaattgtccc tcgttacata gcaaacgaga    540
tagatggtgt tg                                                        552

<210> 1404
<211> 2422
<212> DNA
<213> Homo sapiens

<400> 1404
gccaacagtg ctccctcata gatggacgaa gtgtgacccc ccttcaggct tcagggggac     60
tggtcctcct ggaggagatg ctcgccttgg ggaataatca ctttattggt tttgtgaatg    120
attctgtgac taagtctatt gtggctttgc gcttaactct ggtggtgaag gtcagcacct    180
gtgtgccggg ggagagtcac gcaaatgact tggagtgttc aggaaaagga aaatgcacca    240
cgaagccgtc agaggcaact ttttcctgta cctgtgagga gcagtacgtg ggtactttct    300
gtgaagaata cgatgcttgc cagaggaaac cttgccaaaa caacgcgagc tgtattgatg    360
caaatgaaaa gcaagatggg agcaatttca cctgtgtttg ccttcctggt tatactggag    420
agctttgcca gtccaagatt gattactgca tcctagaccc atgcagaaat ggagcaacat    480
gcatttccag tctcagtgga ttcacctgcc agtgtccaga aggatacttc ggatctgctt    540
gtgaagaaaa ggtggacccc tgcgcctcgt ctccgtgcca gaacaacggc acctgctatg    600
tggacggggt acactttacc tgcaactgca gcccgggctt cacagggccg acctgtgccc    660
agcttattga cttctgtgcc ctcagcccct gtgctcatgg cacgtgccgc agcgtgggca    720
ccagctacaa atgcctctgt gatccaggtt accatggcct ctactgtgag gaggaatata    780
atgagtgcct ctccgctcca tgcctgaatg cagccacctg cagggacctc gttaatggct    840
atgagtgtgt gtgcctggca gaatacaaag gaacacactg tgaattgtac aaggatccct    900
gcgctaacgt cagctgtctg aacggagcca cctgtgacag cgacggcctg aatggcacgt    960
gcatctgtgc acccgggttt acaggtgaag agtgcgacat tgacataaat gaatgtgaca   1020
gtaacccctg ccaccatggt gggagctgcc tggaccagcc caatggttat aactsccact   1080
gcccgcatgg ttgggtggga gcaaactgtg agatccacct ccaatggaag tccgggcaca   1140
tggcggagag cctcaccaac atgccacggc actccctcta catcatcatt ggagccctct   1200
gcgtggcctt catccttatg ctgatcatcc tgatcgtggg gatttgccgc atcagccgca   1260
ttgaatacca gggttcttcc aggccagcct atraggagtt ctacaactgc cgcagcatcg   1320
acagcgagtt cagcaatgcc attgcatcca tccggcatgc caggtttgga aagaaatccc   1380
ggcctgcaat gtatgatgtg agccccatcg cctatgaaga ttacagtcct gatgacaaac   1440
ccttggtcac actgattaaa actaaagatt tgtaatcttt ttttggatta tttttcaaaa   1500
agatgagata ctacactcat ttaaatattt ttaagaaaat aaaaagctta agaaatttaa   1560
aatgctagct gctcaagagt tttcagtaga atatttaaga actaattttc tgcagctttt   1620
agtttggaaa aaatatttta aaaacaaaat ttgtgaaacc tatagacgat gttttaatgt   1680
accttcagct ctctaaactg tgtgcttcta ctagtgtgtg ctcttttcac tgtagacact   1740
atcacgagac ccagattaat ttctgtggtt gttacagaat aagtctaatc aaggagaagt   1800
ttctgtttga cgtttgagtg ccggctttct gagtagagtt aggaaaacca cgtaacgtag   1860
catatgatgt ataatagagt atacccgtta cttaaaaaga agtctgaaat gttcgttttg   1920
tggaaaagaa actagttaaa tttactattc ctaacccgaa tgaaattagc ctttgcctta   1980
ttctgtgcat gggtaagtaa cttatttctg cactgttttg ttgaactttg tggaaacatt   2040
ctttcgagtt tgtttttgtc attttcgtaa cagtcgtcga actaggcctc aaaaacatac   2100
gtaacgaaaa ggcctagcga ggcaaattct gattgatttg aatctatatt tttctttaaa   2160
aagtcaaggg ttctatattg tragtaaatt aaatttacat ttgagttgtt tgttgctaag   2220
aggtagtaaa tgtaagagag tactggttcc ttcagtagtg agtatttctc atagtgcagc   2280
tttatttatc tccaggatgt ttttgtggct gtatttgatt gatatgtgct tcttctgatt   2340
cttgctaatt tccaaccata ttgaataaat gtgatcaagt caaaaaaaaa aaaaaaaaaa   2400
aaaactcgag ggggggtccc gt                                            2422

<210> 1405
<211> 1516
<212> DNA
<213> Homo sapiens

<400> 1405
ctgccatctc ccctcgtcct gcgtcccgga cccatctacg ctgaggacgg agaccgcggc     60
atcaaccagc ccatcatcta cagcatcttt aggggaaacg tgaatggtac attcatcatc    120
cacccagact cgggcaacct caccgtggcc aggagtgtcc ccagccccat gaccttcctt    180
ctgctggtga agggccaaca ggccgacctt gcccgctact cagtgaccca ggtcaccgtg    240
gaggctgtgg ctgcggccgg gagcccgccc cgcttycccc agagactgta tcgtggcamc    300
gtggcgcgtk gcgctggagc gggcgttgtg gtcaaggatg cagctgsccc ttytyagsct    360
ctgaggrtyc aggctcagga cccggagttc tcggacctca actcggccat cacatatcga    420
attaccaacc actcacactt ccggatggag ggagagttgt gctgaccacc accacactgg    480
cacaggcggg agccttctac gcagaggtgc ggggcagggc aggcgggcat ctccaagggt    540
gtggggctta aagatgtgtc taggagggac aagccccttc ctgccccagg ttgaggccca    600
caacacggtg acctctggca ccgcaaccac agtcattgag atacaagttt ccgaacagga    660
gcccccctcc acagcacaga ccccagaggc aggaacctct cagccgatgc cccccggtat    720
gggaaccagc acctcccacc aaccaaccac acccggtggg ggcacagcac agaccccaga    780
gccaggaacc tctcagccga tgcccctcag caagagcacc ccatcttcag gtggcggccc    840
ctcggaggac aagcgcttct cggtggtgga tatggcggcc ctgggcggrg tgctgggtgc    900
gctgctgctg ctggstctcc ttggcctcgc cgtccttgtc cacaagcact atggcccccg    960
ctcaagtgct gctctggcaa agctccggag ccccagcccc aaggctttga caaccaggcg   1020
ttcctccctg accacaaggc maactgggcg cccgtcccca gccccacgca cgaccccaag   1080
cccgcggagg caccgatgcc cgcagagccc gcaccccccg gccctgcctc cccaggcggt   1140
gccctgagcc ccccgcagcg gcccgagctg gcggaagccc cacggcggtg aggtccatcc   1200
tgaccaagga gcggcggcca gagggcgggt acaaggctgt ctggtttggc gaggacatcg   1260
ggacggaggc agacgtggtc gttctcaacg cgcccaccct ggacgtggat ggcgccagtg   1320
actccggcag cggcgatgag ggcgagggcg cggggagggg tgggggtccc tacgatgcgc   1380
ccggtggtga tgactcctac atctaagtgg cccctccacc ctctccccca gccgcacggg   1440
cactggaggt ctcgctcccc cagcctccga cccgaggcag aataaagcaa ggctcccgaa   1500
aaaaaaaaaa aaaaaa                                                   1516

<210> 1406
<211> 1187
<212> DNA
<213> Homo sapiens

<400> 1406
tcccggtcga cccacgacgt ccgcccgccc gccccgccgc tcctcctccc tgtaacatgc     60
catagtgcgc ctgcraccac acggccgggg cgctagcgtt cgccttcagc caccatgggg    120
aatgggatga acaagatcct gcccggcctg tacatcggca acttcaaaga tgccagagac    180
gcggaacaat tgagcaagaa caaggtgaca catattctgt ctgtccacga tagtgccagg    240
cctatgttgg agggagttaa atacctgtgc atcccagcag cggattcacc atctcaaaac    300
ctgacaagac atttcaaaga aagtattaaa ttcattcacg agtgccggct ccgcggtgag    360
agctgccttg tacactgcct ggccggggtc tccaggagcg tgacactggt gatcgcatac    420
atcatgaccg tcactgactt tggctgggag gatgccctgc acaccgtgcg tgctgggaga    480
tcctgtgcca accccaacgt gggcttccag agacagctcc aggagtttga gaagcatgag    540
gtccatcagt atcggcagtg gctgaaggaa gaatatggag agagcccttt gcaggatgca    600
gaagaagcca aaaacattct ggccgctccr ggaattctga agttctgggc ctttctcaga    660
agactgtaat gtacctgaag tttctgaaat attgcaaacc cacagagttt aggctggtgc    720
tgccaaaaag aaaagcaaca tagagtttaa gtatccagta gtgatttgta aacttgtttt    780
tcatttgaag ctgaatatat acgtagtcat gtttatgttg agaactaagg atattcttta    840
gcaagagaaa atattttccc cttatcccca ctgctgtgga ggtttctgta cctcgcttgg    900
atgcctgtaa ggatcccggg agccttgccg cactgccttg tgggtggctt ggcgctcgtg    960
attgcttcct gtgaacgcct cccaaggacg agcccagtgt agttgtgtgg cgtgaactct   1020
gcccgtgtgt tctcaaattc cccagcttgg gaaatagccc ttggtgtggg ttttatctct   1080
ggtttgtgtt ctccgtggtg gaattgaccg aaagctctat gttttcgtta ataaagggca   1140
acttagccaa gtttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa                 1187

<210> 1407
<211> 467
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (342)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (465)
<223> n equals a,t,g, or c

<400> 1407
cgaaagtcgg ggcctcgatg ggtcattgca gaggagggcg ggcatgcggt tttytcctgc     60
tctggagatg gagacccagc ccccactgtc tcctggatga ggcctcatgg ggcttggctg    120
ggcagggctg ggagagtaag ggtcctagag gatgggacac tggagatccg ytcagtgcag    180
ctacgggaca gaggggccta tgtctgtktg gttagcaatg tcgctgggaa tractccctg    240
aggacctggc tggaagtcat ccaggtggaa ccaccaaacg gaacactttc tgaccccaac    300
atcaccgtgc cagggatccc agggcctttt tttctggata gnagaggtgt ggccatggtg    360
ctggaagtcg gtttcctccc cttcctcacc tcagtgaccc tctgttttgg cctgattgcc    420
cttgggagca agggcaaagg tcgggtcaaa catcacatga ccttnga                  467

<210> 1408
<211> 1200
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1182)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1186)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1192)
<223> n equals a,t,g, or c

<400> 1408
gcggccgcag ccgctgcccc gggccgggcg cccgcggcgg caccatgagt ccccgctcgt     60
gcctgcgttc gctgcgcctc ctcgtcttcg ccgtcttctc agccgccgcg agcaactggc    120
tgtacctggc caagctgtcg tcggtgggga gcatctcaga ggaggagacg tgcgagaaac    180
tcaagggcct gatccagagg caggtgcaga tgtgcaagcg gaacctggaa gtcatggact    240
cggtgcgccg cggtgcccag ctggccattg aggagtgcca gtaccagttc cggaaccggc    300
gctggaactg ctccacactc gactccttgc ccgtcttcgg caaggtggtg acgcaaggga    360
ctcgggaggc ggccttcgtg tacgccatct cttcggcagg tgtggccttt gcagtgacgc    420
gggcgtgcag cagtggggag ctggagaagt gcggctgtga caggacagtg catggggtca    480
gccacagggc ttccagtggt caggatgctc tgacaacatc gcctacggtg tggccttctc    540
acagtcgttt gtggatgtgc gggagagaag caagggggcc tcgtccagca gagccctcat    600
gaacctccac aacaatgagg ccggcaggaa ggccatcctg acacacatgc gggtggaatg    660
caagtgccac ggggtgtcag gctcctgtga ggtaaagacg tgctggcgag ccgtgccgcc    720
cttccgccag gtgggtcacg cactgaagga gaagtttgat ggtgccactg aggtggagcc    780
acgccgcgtg ggctcctcca gggcactggt gccacgcaac gcacagttca agccgcacac    840
agatgaggac ctggtgtact tggagcctag ccccgacttc tgtgagcagg acatgcgcag    900
cggcgtgctg ggcacgaggg gccgcacatg caacaagacg tccaaggcca tcgacggctg    960
tgagctgctg tgctgtggcc gcggcttcca cacggcgcag gtggagctgg ctgaacgctg   1020
cagctgcaaa ttccactggt gctgcttcgt caagtgccgg cagtccagcg gctcgtggag   1080
ttgcacacgt gccgatgacc gcctgcctag ccctgcgccg gcaaccacct agtggcccag   1140
ggaaggccga taatttaaac agtctcccac cacctaaaaa anaaanaaaa anaaaaaaaa   1200

<210> 1409
<211> 2884
<212> DNA
<213> Homo sapiens

<400> 1409
caaggattgt agcttggact gtgcgggttc gccccagaaa cctctctgcg catctgacgg     60
aaggaccttc ctttcccgtt gtgaatttca acgtgccaag tgcaaagatc cccagctaga    120
gattgcatat cgaggaaact gcaaagacgt gtccaggtgt gtggccgaaa ggaagtatac    180
ccaggagcaa gcccggaagg agtttcagca agtgttcatt cctgagtgca atgacgacgg    240
cacctacagt cargtccagt gtcacagcta cacgggatac tgctggtgcg tcacgcccaa    300
cgggaggccc atcagcggca ctgccgtggc ccacaagacg ccccggtgcc cgggttccgt    360
aaatgaaaag ttaccccaac gcgaaggcac aggaaaaaca gatgatgccg cagctccagc    420
gttggagact cagcctcaag gagatgaaga agatattgca tcacgttacc ctaccctttg    480
gactgaacag gttaaaagtc ggcagaacaa aaccaataag aattcagtgt catcctgtga    540
ccaagagcac cagtctgccc tggaggaagc caagcagccc aagaacgaca atgtggtgat    600
ccctgagtgt gcgcacggcg gcctctacaa gccagtgcag tgccacccct ccacggggta    660
ctgctggtgc gtcctggtgg acacggggcg ccccattccc ggcacatcca caaggtacga    720
gcagccgaaa tgtgacaaca cggccagggc ccacccagcc aaagcccggg acctgtacaa    780
gggccgccag ctacaaggtt gtccgggtgc caaaaagcat gagtttctga ccagcgttct    840
ggacgcgctg tccacggaca tggtccacgc cgcctccgac ccctcctcct cgtcaggcag    900
gctctcagaa cccgacccca gccataccct agaggagcgg gtggtgcact ggtacttcaa    960
actactggat aaaaactcca gtggagacat cggcaaaaag gaaatcaaac ccttcaagag   1020
gttccttcgc aaaaaatcaa agcccaaaaa atgtgtgaag aagtttgttg aatactgtga   1080
cgtgaataat gacaaatcca tctccgtaca agaactgatg ggctgcctgg gcgtggcgaa   1140
agaggacggc aaagcggaca ccaagaaacg ccacaccccc agaggtcatg ctgaaagtac   1200
gtctaataga cagccaagga aacaaggata aatggctcat accccgaagg cagttcctag   1260
acacatggga aatttccctc accaaagagc aattaagaaa acaaaaacag aaacacatag   1320
tatttgcact ttgtacttta aatgtaaatt cactttgtag aaatgagcta tttaaacaga   1380
ctgttttaat ctgtgaaaat ggagagctgg cttcagaaaa ttaatcacat acaatgtatg   1440
tgtcctcttt tgaccttgga aatctgtatg tggtggagaa gtatttgaat gcatttaggc   1500
ttaatttctt cgccttccac atgttaacag tagagctcta tgcactccgg ctgcaatcgt   1560
atggctttct ctaacccctg cagtcacttc cagatgcctg tgcttacagc attgtggaat   1620
catgttggaa gctccacatg tccatggaag tttgtgatgt acggccgacc ctacaggcag   1680
ttaacatgca tgggctggtt tgtttcttgg gattttctgt tagtttgtct tgttttgctt   1740
tccagagatc ttgctcatac aatgaatcac gcaaccacta aagctatcca gttaagtgca   1800
ggtagttccc ctggaggaaa taatattttc aaactgtcgt tggtgtgata ctttggctca   1860
aaggatcttt gcttttccat tttaagcttc tgttttgagt tttgccctgg ggcttgaatg   1920
agtcccagag agtcgttcgg atggtgggag gctgcctagg aggcagtaaa tccagtcaca   1980
gtgcctggga ggggcccatc cttccaaaat gtaaatccag tcgcggtgtg accgagctgg   2040
ctaacaggct tgtctgcctg gttttcctcc tacacgtgga cattattctc ctgatcctcc   2100
tacctggtcc accccagggc taccggaagg taaaatcttc acctgaacca attatgagca   2160
gtctccttac tgaaggtaca gccggatacg tggtgccccc ggggctggtg ttggcagccg   2220
gggggaggtg cctgagggtc cccacggttc ctttctgctt ttctgaatgc atcaagggta   2280
cgagaacttg ccaatgggaa attcatccga gtggcactgg cagagaagga taggagtgga   2340
atgcccacac agtgaccaac agaactggtc tgcgtgcata accagctgcc accctcaggc   2400
ctgggcccca gagctcaggg cacccagtgt cttaaggaac catttggagg acagtctgag   2460
agcaggaact tcaagctgtg attctatctc ggctcagact tttggttgga aaaagatctt   2520
catggcccca aatcccctga gacatgcctt gtagaatgat tttgtgatgt tgtgatgctt   2580
gtggagcatc gcgtaaggct tcttgcttat ttaaactgtg caaggtaaaa atcaagcctt   2640
tggagccaca gaaccagctc aagtacatgc caatgttgtt taagaaacag ttatgatcct   2700
aaactttttg gataatcttt tatatttctg acctttgaat ttaatcattg ttcttagatt   2760
aaaataaaat atgctattga aactaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa   2820
aaaaaaaaaa aaaaaaaaaa aaaaactcga gggggggccc gtacccaatt cgccctatag   2880
tgag                                                                2884

<210> 1410
<211> 1294
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1271)
<223> n equals a,t,g, or c

<400> 1410
ggcagagcgc cgaaggaggc ggaaggagca gaggaccggc agccggcgtc gaggcggggc     60
gcgggaacga cggcggccat ggcggcctcg gggcccgggt gtcgcagctg gtgcttgtgt    120
cccgaggtgc catccgccac cttcttcact gcgctgctct cgctgctggt ttccgggcct    180
cgcctgttcc tgctgcagca gcccctggcg ccctcgggcc tcacgctgaa gtccgaggcc    240
cttcgcaact ggcaagttta caggctggta acctacatct ttgtctacga gaatcccatc    300
tccctgctct gcggcgctat catcatctgg cgctttgctg gcaatttcga gagaaccgtg    360
ggcaccgtcc gccactgctt cttcaccgtg atcttcgcca tcttctccgc tatcatcttc    420
ctgtcattcg aggctgtgtc atcactgtca aagctggggg aagtggagga tgccagaggt    480
ttcaccccag tggcctttgc catgctggga gtcaccaccg tccgttctcg gatgaggcgg    540
gccctggtgt ttggcatggt tgtgccctca gtcctggttc cgtggctcct gctgggtgcc    600
tcgtggctca ttccccagac ctctttcctc agtaatgtct gcgggctgtc catcgggctg    660
gcctatggcc tcacctactg ctattccatc gacctctcag agcgagtggc gctgaagctc    720
gatcagacct tccccttcag cctgatgagg aggatatccg tgttcaagta cgtctcaggg    780
tcttcagccg agaggagggc agcccagagc cggaaactga acccggtgcc tggctcctac    840
cccacacaga gctgccaccc tcacctgtcc ccaagccacc ctgtgtccca gacgcagcac    900
gccagtggtc agaagctggc ctcctggccc tcctgcaccc ccgggcacat gcccaccttg    960
cctccgtacc agcctgcctc cggcctgtgc tatgtgcaga accactttgg tccaaacccc   1020
acctcctcca gtgtctaccc agcttctgcg ggcacctccc tgggcatcca gccccccacg   1080
cctgtgaaca gccctggcac ggtgtattct ggggccttgg gcacaccagg ggctgcaggc   1140
tccaaggagt cctccagggt ccccatgccc tgagagaatt tctagggaag tcatctcact   1200
tggccttctg aaggtcctcc ctaagagtct cctgacaaaa gttacttatt gaacacctct   1260
atgtgccarg ntcygtgttg gggamtttga tcca                               1294

<210> 1411
<211> 1500
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1380)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1406)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1477)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1484)
<223> n equals a,t,g, or c

<400> 1411
cgggccccag gcagctgcgc ccccggcgtc gccagagcct ttcgcgcaca tccaggcagt     60
gtttgcaggg agtgacgacc cctttgccac cgccctgagc atgagcgaga tggaccggag    120
gaacgacgcc tggcttcccg gcgaggctac gcgtggagtc ctgcgggccg tggccaccca    180
gcagcgcggc gccgtgttcg tggacaagga gaacctcacc atgccgggcc tcaggttcga    240
caacatccag ggagatgcag ttaaagactt gatgcttcgc tttctgggtg aaaaagctgc    300
agcaaagaga caagtcctaa atgccgactc agtggaacaa tcttttgttg gattgaaaca    360
gctaatcagc tgcagaaact ggagggcagc agtggacctg tgcggacgtc tcctcacagc    420
ccacggccag ggctacggca agagcgggct gctcaccagc cacacgacag attcactgca    480
gctctggttt gtcaggctgg cactactagt gaagttgggc cttttccaga atgctgagat    540
ggaatttgaa cccttcggaa atcttgatca gccagatctt tattacgagt actacccgca    600
cgtgtaccct gggcgcaggg gctccatggt ccccttctcg atgcgcatct tgcacgcgga    660
gcttcagcag tacctgggga acccacagga gtcgctggat agactgcaca aggtgaagac    720
tgtctgcagc aagatcctgg ccaatttgga gcaaggctta gcagaagacg gcggcatgag    780
cagcgtgact caggagggca gacaagcctc tatccggctg tggaggtcac gtctgggccg    840
ggtgatgtac tccatggcaa actgtctgct cctgatgaag gattatgtgc tggccgtgga    900
ggcgtatcat tcggttatca agtattaccc agagcaagag ccccagctgc tcagcggcat    960
cggccggatt tccctscaga ttggagacat aaaaacagct gaaaagtatt ttcaagacgt   1020
tgagaaagta acacagaaat tagatggact acagggtaaa atcatggttt tgatgaacag   1080
cgcgttcctt cacctcgggc agaataactt tgcagaagcc cacaggttct tcacagagat   1140
cttaaggatg gatccaagaa acgcagtggc caacaacaac gctgccgtgt gtctgctcta   1200
cctgggcaag ctcaaggact ccctgcggca gctggaggcc atggtccagc aggaccccag   1260
gcactacctg cacgagagcg tgctcttcaa cctgaccacc atgtacgagc tggagtccta   1320
cggagcatgc agaagaaaca ggccctgctg gaagctgtcg ccggcaagga gggggacagn   1380
ttcaacacac agtgccttaa gctggnctaa cttgcttcaa cacactacgt cagaaggacc   1440
cggtctttga actggggctt gaactaagga ttaatgngcc tggnggacta ataaactctg   1500

<210> 1412
<211> 522
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (1)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (5)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (15)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (45)
<223> n equals a,t,g, or c

<400> 1412
ngggntactt ctacngaaag accctgaccc tgtttagacc ctgantcaag acatggcttg     60
agtgtgtgaa tatgatgtgt gcacatgctt aatgagcgtg caagtgtgca cacgtttgtg    120
gagaggaggg tgttctggcc tgagaaggta aagaagaggc atgtccagta tgctttgcag    180
ggtgtgtttg ctcttttcca tgcccatgca acccagattg gggtggagca ggaaggagct    240
cttttctgtt cccaagcctc agaactcttg agctgtggct tacttgctgt cttcaccagg    300
ttcaagctcc gtgggccaca ctgctgctgt gccaagaagg tgtacagcct ccccaggatg    360
gggcctcata caacccttca tctgcactca acatttaatc gtgtccttgc tgtcttttta    420
ttttcctttt tgtttgttag caaaaacctc tatttagatt tcaataatca gagaagtgta    480
aaataaaaca gattatattg taaaaaaaaa aaaaaaaaac tc                       522

<210> 1413
<211> 692
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (501)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (632)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (678)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (680)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (690)
<223> n equals a,t,g, or c

<400> 1413
taacctacct aagccacgag cactgggaga caagcctcga gacctgtatc ccctctcccg     60
ctgcaggaag aacctctcta tccagggcct ccgctggtgg ctacagtggc tgggcatcaa    120
cttcaccctt ttcctggggc tatttttcct gaccacaccc tccatcatcc tgtccaccat    180
ggacaagttt aatgtcacca aacccatcca tgcgctgaat aacccgatca tcagccagtt    240
cttccccacc ctcctgctct ggtccttmtc ggccctgmtc ccctccattg tctactactc    300
tacactgctg gagtctcact ggaccaagtc gggggaaaac cagatcatga tgaccaaagt    360
ctacatattc ttgatcttca tggtgctgat cctgccctcc ctgggtctca ccagtctaga    420
ttttttcttc cggtggctct ttgacaaaac ttcctcggaa gcctccatca ggtttggagt    480
gcgtcttccc tgcctgacca nggtgccttc tttgtgaact atgtcatcgc ctccggcttc    540
atccgcaatg gcatggactt gctgcggctg ccaagtctca tcctctatac ttccgcatga    600
tcatggcaaa aagctgtgac gcaagaatgt cnacaaaacc aagctccata caatttggag    660
cattttgatg atgtgttntn tcctgtatcn tg                                  692

<210> 1414
<211> 1070
<212> DNA
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (40)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (525)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (529)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (557)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (837)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (912)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (956)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (965)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (966)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1025)
<223> n equals a,t,g, or c

<220>
<221> SITE
<222> (1047)
<223> n equals a,t,g, or c

<400> 1414
ggggggggag tgatatgtat ttggaggctc tctntatgan agacaaggag gaaggacatg     60
gataaagcag atgtttattg gggcattcct tatcccagct atggtgtgtg gcactgcctt    120
cttcatcaat ttcatagcca tttattacca tgcttcaaga gccattcctt ttggaacaat    180
ggtggccgtt tgttgcatct gtttttttgt tattcttcct ctaaatcttg ttggtacaat    240
acttggccga aatctgtcag gtcagcccaa ctttccttgt cgtgtcaatg ctgtgcctcg    300
tcctataccg gagaaaaaat ggttcatgga gcctgcggtt attgtttgcc tgggtggaat    360
tttacctttt ggttcaatct ttattgaaat gtatttcatc ttcacgtctt tctgggcata    420
taagatctat tatgtctatg gcttcatgat gctggtgctg gttatcctgt gcattgtgac    480
tgtctgtgtg actattgtgt gcacatattt tctactaaat gcagnaagna ttaccggtgt    540
gccattcatt caaaagnaga tttatcttct ttccccctcc cgccaccagg caatggacaa    600
gttttctctc tgctgcatca actgcaatct atgtttacat gtattccttt tactactatt    660
ttttcaaaac aaagatgtat ggcttatttc aaacatcatt ttactttgga tatatggcgg    720
tatttagtac agccttgggg gataatgtgt ggagcgattg gttacatggg aacaagtgcc    780
tttgtccgaa aaatctatac taatgtgaaa attgactaga gacccaagaa aacctgnaac    840
tttggatcaa tttctttttc ataggggtgg aacttgcaca gcaaaaacaa acaaacgcaa    900
gaagagattt gngctttaac acactggggt actttggggg tctctctttc gtcggnggct    960
taaannaaca tctatttcca tggatcctag gttcttcctg gactgctttc ttcaactgtt   1020
cacancaaaa gcttggaatt tatgcantag gcattactac agtacatggg              1070

<210> 1415
<211> 1219
<212> DNA
<213> Homo sapiens

<400> 1415
cactctaaag ttggtacgcc tgcagctacc ggtccggaat tcccggtcga cccacgcgtc     60
cgaacctgac agcacagcct gagatcttgg ggatccctca gcctaacacc cacagacgtc    120
agctggtgga ttcccgctgc atcaaggcct acccactgtc tccatgctgg gctctccctg    180
ccttctgtgg ctcctggccg tgaccttctt ggttcccaga gctcagccct tggcccctca    240
agactttgaa gaagaggagg cagatgagac tgagacggcg tggccgcctt tgccggctgt    300
cccctgcgac tacgaccact gccgacacct gcaggtgccc tgcaaggagc tacagagggt    360
cgggccggcg gcctgcctgt gcccaggact ctccagcccc gcccagccgc ccgacccgcc    420
gcgcatggga gaagtgcgca ttgcggccga agagggccgc gcagtggtcc actggtgtgc    480
ccccttctcc ccggtcctcc actactggct gctgctttgg gacggcagcg aggctgcgca    540
gaaggggccc ccgctgaacg ctacggtccg cagagccgaa ctgaaggggc tgaagccagg    600
gggcatttat gtcgtttgcg tagtggccgc taacgaggcc ggggcaagcc gcgtgcccca    660
ggctggagga gagggcctcg agggggccga catccctgcc ttcgggcctt gcagccgcct    720
tgcggtgccg cccaaccccc gcactctggt ccacgcggcc gtcggggtgg gcacggccct    780
ggccctgcta agctgtgccg ccctggtgtg gcacttctgc ctgcgcgatc gctggggctg    840
cccgcgccga gccgccgccc gagccgcagg ggcgctctga aaggggcctg ggggcatctc    900
gggcacagac agccccacct ggggcgctca gcctggcccc cgggaaagag gaaaacccgc    960
tgcctccagg gagggctgga cggcgagctg ggagccagcc ccaggctcca gggccacggc   1020
ggagtcatgg ttctcaggac tgagcgcttg tttaggtccg gtacttggcg ctttgtttcc   1080
tggctgaggt ctgggaagga atagaaaggg gcccccaatt tttttttaag cggccagata   1140
ataaataatg taacctttgc ggtttaagag gataaaaaaa aaaaaaaaaw aaawaaaaaa   1200
aaaaaaaact ckagggggg                                                1219

<210> 1416
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1416
Met Pro Ser Pro Gln Leu Leu Val Leu Phe Gly Ser Gln Thr Gly Thr
  1               5                  10                  15

Ala Gln Asp Val Ser Glu Arg Leu Gly Arg Glu Ala Arg Arg Arg Arg
             20                  25                  30

Leu Gly Cys Arg Val Gln Ala Leu Asp Ser Tyr Pro Val Val Asn Leu
         35                  40                  45

Ile Asn Glu Pro Leu Val Ile Phe Val Cys Ala Thr Thr Gly Gln Gly
     50                  55                  60

Asp Pro Pro Asp Asn Met Lys Asn Phe Trp Arg Phe Ile Phe Arg Lys
 65                  70                  75                  80

Asn Leu Pro Ser Thr Ala Leu Cys Gln Met Asp Leu Ala Val Leu Gly
                 85                  90                  95

Leu Arg Gly Ser Ser Tyr Ala Asn Phe Asn Phe Val Gly Gln Glu Val
            100                 105                 110

His Arg Arg Val Met Ala Xaa Leu Gly Gly Arg Ala Ser Xaa Ala Arg
        115                 120                 125

Val Xaa Leu Gly Asp Glu Pro Ala 
    130                 135



<210> 1417
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1417
Met Trp Asp Val Leu Leu Ala Val Lys Xaa Trp Gly Val Cys Arg Glu
  1               5                  10                  15

Pro Gly Pro Gly Val Pro Arg Gly Ala Ser Trp Gly Gly Leu His Ser
             20                  25                  30

Arg Ile Leu Pro Met Cys Pro Glu Leu Met Cys Gln Pro Cys Glu Ser
         35                  40                  45

Ala Leu Thr Pro Trp Ala Val Arg Arg Ala Ser Arg Gly Asp Val Glu
     50                  55                  60

Gly Arg Arg Gln Leu Cys Arg Glu Pro Leu Gln Ala Val Glu Gly Pro
 65                  70                  75                  80

Ser Cys Asp Val Ser Cys Pro Pro Cys Phe His Leu Trp Cys Leu Leu
                 85                  90                  95

Ala Ser Cys Val Gln Gly Pro Phe Ala Cys Ser Ala Met Phe Leu His
            100                 105                 110

Leu Ser Phe Ala Phe Cys Lys Leu Leu Gly Ser Phe Ser Phe Asp Gly
        115                 120                 125

Ile Gly Thr Xaa Ile Tyr Pro Xaa Cys Trp Ala Arg Val Xaa Thr 
    130                 135                 140



<210> 1418
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1418
Met Ala Gly Leu Ala Ile Leu Ala Asn Met Leu Val Pro Gln Asp Leu
  1               5                  10                  15

Gln Thr Leu Arg Val Val Phe Ala Val Leu Gly Lys Gly Cys Phe Gly
             20                  25                  30

Ile Ser Leu Thr Cys Leu Thr Ile Tyr Lys Ala Glu Leu Phe Pro Thr
         35                  40                  45

Pro Val Arg Met Thr Ala Asp Gly Ile Leu His Thr Val Gly Arg Leu
     50                  55                  60

Gly Ala Met Met Gly Pro Leu Ile Leu Met Ser Arg Gln Ala Leu Pro
 65                  70                  75                  80

Leu Leu Pro Pro Leu Leu Tyr Gly Val Ile Ser Ile Ala Ser Ser Leu
                 85                  90                  95

Val Val Leu Phe Phe Leu Pro Glu Thr Gln Gly Leu Pro Xaa Pro Asp
            100                 105                 110

Thr Ile Gln Asp Leu Glu Ser Gln Lys Ser Thr Ala Ala Gln Gly Asn
        115                 120                 125

Arg Gln Glu Ala Phe Thr Val Glu Ser Thr Ser Leu Leu Glu Ile Val
    130                 135                 140

Ala Leu His Gly Ala Leu 
145                 150



<210> 1419
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1419
Met Leu Leu Thr Leu Glu Lys Ala Glu Thr Lys Ala His Leu Pro Ser
  1               5                  10                  15

Leu Leu Ser Pro Val Thr Leu Gln Ile Asp Val Trp Glu Gly Ser Xaa
             20                  25                  30

Ala Xaa Arg Xaa Arg Xaa Xaa Xaa Xaa Leu Leu Cys Leu Leu Ala Xaa
         35                  40                  45

Xaa Leu Xaa Xaa Xaa Gly Met Val Cys Ala Trp Xaa Xaa Xaa Xaa Ser
     50                  55                  60

Ser Phe Pro Gly Thr Leu Met Pro His Asn Pro Ala Xaa Pro Gln Ser
 65                  70                  75                  80

Arg Pro Gln Ala Pro Val Cys Val Gly Ser Xaa Xaa Xaa Xaa Ser Thr
                 85                  90                  95

Ser Arg Leu Trp Ser Thr Lys Gly Gly Lys Leu Arg Val Xaa Gly Leu
            100                 105                 110

Val Cys Arg Gly Arg Trp Leu Asn 
        115                 120



<210> 1420
<211> 117
<212> PRT
<213> Homo sapiens

<400> 1420
Met Phe Leu Ser Ser Val Gly Phe Ser Val Val Met Met Ser Ile Trp
  1               5                  10                  15

Pro Tyr Leu Gln Lys Ile Asp Pro Thr Ala Asp Thr Ser Phe Leu Gly
             20                  25                  30

Trp Val Ile Ala Ser Tyr Ser Leu Gly Gln Met Val Ala Ser Pro Ile
         35                  40                  45

Phe Gly Leu Trp Ser Asn Tyr Arg Pro Arg Lys Glu Pro Leu Ile Val
     50                  55                  60

Ser Ile Leu Ile Ser Val Ala Ala Asn Cys Leu Tyr Ala Tyr Leu His
 65                  70                  75                  80

Ile Pro Ala Ser His Asn Lys Tyr Tyr Met Leu Val Ala Arg Gly Leu
                 85                  90                  95

Leu Gly Ile Gly Ala Gly Lys Val Val Cys Ile Cys Leu Val Val Ser
            100                 105                 110

Tyr Ser His Ser Phe 
        115



<210> 1421
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1421
Met Gly Tyr Cys Ser Gly Arg Cys Thr Leu Ile Phe Ile Cys Gly Met
  1               5                  10                  15

Gln Leu Val Cys Val Leu Glu Arg Gln Ile Phe Asp Phe Leu Gly Tyr
             20                  25                  30

Gln Trp Ala Pro Ile Leu Ala Asn Phe Val His Ile Ile Ile Val Ile
         35                  40                  45

Leu Gly Leu Phe Gly Thr Ile Gln Tyr Arg Pro Arg Tyr Ile Thr Gly
     50                  55                  60

Tyr Ala Val Trp Leu Val Leu Trp Val Thr Trp Asn Val Phe Val Ile
 65                  70                  75                  80

Cys Phe Tyr Leu Glu Ala Gly Asp Leu Ser Lys Glu Thr Asp Leu Ile
                 85                  90                  95

Xaa Thr Phe Asn Ile Ser Met His Arg Ser Trp Trp Xaa Glu Asn Gly
            100                 105                 110

Pro Gly Cys Thr Val Thr His Gly His Leu Pro Gln Thr Gly Pro Gln
        115                 120                 125

Lys Thr Ile Ala Thr Ser Arg Ser Gln Val Phe Ala Gly Tyr His Thr
    130                 135                 140






<210> 1422
<211> 219
<212> PRT
<213> Homo sapiens

<400> 1422
Met His Gln Glu Asp Phe Ser Gly Ser Leu Ser Ser Ser Gly Lys Pro
  1               5                  10                  15

Asp Val Pro Cys Ser Leu Tyr Met Lys Glu Leu Gln Gly Phe Ile Ala
             20                  25                  30

Arg Val Met Ser Asp Tyr Phe Lys His Phe Glu Cys Leu Asp Phe Val
         35                  40                  45

Phe Asp Asn Thr Glu Ala Ile Ala Gln Arg Ala Val Glu Leu Phe Ile
     50                  55                  60

Arg His Ala Ser Leu Ile Arg Pro Leu Gly Glu Gly Gly Lys Met Arg
 65                  70                  75                  80

Leu Ala Ala Asp Phe Ala Gln Met Glu Leu Ala Val Gly Pro Phe Cys
                 85                  90                  95

Arg Arg Val Ser Asp Leu Gly Lys Ser Tyr Arg Met Leu Arg Ser Phe
            100                 105                 110

Arg Pro Leu Leu Phe Gln Ala Ser Glu His Val Ala Ser Ser Pro Ala
        115                 120                 125

Leu Gly Asp Val Ile Pro Phe Ser Ile Ile Ile Gln Phe Leu Phe Thr
    130                 135                 140

Arg Ala Pro Ala Glu Leu Lys Ser Pro Phe Gln Arg Ala Glu Trp Ser
145                 150                 155                 160

His Thr Arg Phe Ser Gln Trp Leu Asp Asp His Pro Ser Glu Lys Asp
                165                 170                 175

Arg Leu Leu Leu Ile Arg Gly Ala Leu Glu Ala Tyr Val Gln Ser Val
            180                 185                 190

Arg Ser Arg Glu Gly Lys Glu Phe Ala Pro Val Tyr Pro Ile Met Val
        195                 200                 205

Gln Leu Leu Gln Lys Ala Met Ser Ala Leu Gln 
    210                 215



<210> 1423
<211> 132
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1423
Met Thr Leu Val Gly His Trp Gly Arg Cys Tyr Leu Leu Thr Glu Arg
  1               5                  10                  15

Arg Ser Leu Pro Cys Gly Leu Thr Glu His Val Phe Arg Pro Ala Pro
             20                  25                  30

Ser Ser Leu Ala Asp Ala Glu Asp Ala Arg Lys Ala Thr Cys Leu Met
         35                  40                  45

Leu Ala Trp Pro Gly Asp Arg Ser Pro Leu Gly Leu Cys Pro Val Ala
     50                  55                  60

Ala Gly Leu Ala Gly Arg Gly Ala Gln Xaa Trp Gly Ala Ser Glu Trp
 65                  70                  75                  80

Ser Pro Thr Phe Gln Pro Trp Gly Cys Cys Ile Gly Leu Pro His Val
                 85                  90                  95

Thr Ser Gln Ala Leu Met Leu Leu Leu Leu Lys Gly Val Arg Pro Asp
            100                 105                 110

Gly Gln Val Lys Ser Val Leu Gln Gly Gly Val Tyr Leu Pro Cys Pro
        115                 120                 125

Gly Val Val Pro 
    130



<210> 1424
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1424
Met Asn Leu Glu Leu Gly Glu Asp Leu Asn Phe Asn Gln Thr Pro Gly
  1               5                  10                  15

Pro Arg Lys Ile Thr Ile Glu Asn Val Gln Gly Ser Val Phe Asn Ile
             20                  25                  30

Lys Leu Pro Gln Gly Lys His Lys Leu Val Phe Leu Glu Arg Glu Lys
         35                  40                  45

Gly Leu Ser His Thr Val Leu Val Phe Glu Ala Val Leu Val Ser Arg
     50                  55                  60

Gly Trp Cys Gln Asn Gly Ser Pro Ile Val Val Thr Leu Arg Trp Ala
 65                  70                  75                  80

Ser Cys Thr Ile Leu Leu Cys Gln Ile Val Phe Lys Gln Trp Val Gly
                 85                  90                  95

Gly Val Thr Gly Asp Lys Glu Leu Val Leu Lys Ser Phe Thr Lys Pro
            100                 105                 110

Lys Thr Gly Xaa Val 
        115



<210> 1425
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (65)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1425
Met Trp Arg Pro Val Gln Leu Cys His Phe His Ser Ala Leu Leu His
  1               5                  10                  15

Xaa Arg Gln Lys Pro Trp Pro Ser Pro Ala Val Phe Phe Arg Arg Asn
             20                  25                  30

Val Arg Gly Leu Pro Pro Arg Phe Ser Ser Pro Thr Pro Leu Trp Arg
         35                  40                  45

Lys Val Leu Ser Thr Ala Val Val Gly Ala Pro Leu Leu Leu Gly Ala
     50                  55                  60

Xaa Tyr Val Met Ala Glu Ala Arg Glu Lys Arg Arg Met Arg Leu Val
 65                  70                  75                  80

Val Asp Gly Met Gly Arg Phe Gly Arg Ser Leu Lys Ser Ala Cys Xaa
                 85                  90                  95

Ser Pro Trp Thr 
            100



<210> 1426
<211> 118
<212> PRT
<213> Homo sapiens

<400> 1426
Met Ser Ser Arg Pro Gly Thr Gly Gly Cys Arg Trp Ser Thr Gly Ser
  1               5                  10                  15

Ala Pro Gly Leu Cys Trp Ala His Cys Phe Thr Ile Ala Gly Gln Trp
             20                  25                  30

Arg Ser Arg Gln Thr Lys Arg Met Ala Gln Gln Val Lys Tyr Pro Val
         35                  40                  45

Asn Ser Leu Asn Ala Gln Lys Asp Phe Met Trp Lys Gln Leu Ser His
     50                  55                  60

Ile Lys Lys Ile Leu Phe Gln Ile Gln Lys Arg Ser Ser Thr Ile Gly
 65                  70                  75                  80

Asn His Gly Leu Val Ala Leu Val Gln Asn His Asp Trp Leu Leu Asn
                 85                  90                  95

Ser Glu Asn Gln Asp Leu Val Gln His Leu Asn Leu Ile Val Ala Leu
            100                 105                 110

Ile Pro Ile Leu Gly Leu 
        115



<210> 1427
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1427
Met Leu Gly Ser Leu Leu Ala Phe His Tyr Gly Leu Tyr Phe Tyr Thr
  1               5                  10                  15

Val Lys Phe Leu Ala Val Val Phe Cys Leu Ile Gly Tyr Val Pro Ser
             20                  25                  30

Val Ile Leu Phe Thr Tyr Ile Ala Ser Phe Thr Phe Lys Lys Ile Leu
         35                  40                  45

Asn Thr Lys Glu Phe Trp Ser Phe Ile Tyr Ser Val Ala Ala Leu Ala
     50                  55                  60

Cys Ile Ala Ile Thr Glu Ile Thr Phe Phe Met Gly Tyr Thr Ile Ala
 65                  70                  75                  80

Thr Ile Xaa His Tyr Ala Phe Cys Ile Ile Ile Pro Ile Tyr Pro Leu
                 85                  90                  95

Leu Gly Cys Leu Ile Ser Phe Ile Lys Ile Ser Trp Xaa Asn Val Arg
            100                 105                 110

Lys Met Trp Asp Thr Tyr Asn Pro Gly Ile Gly Phe Gln 
        115                 120                 125



<210> 1428
<211> 191
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1428
Met Pro Pro Gly Pro Trp Glu Ser Cys Phe Trp Val Gly Gly Leu Ile
  1               5                  10                  15

Leu Trp Leu Ser Val Gly Xaa Ser Gly Asp Ala Pro Pro Thr Pro Gln
             20                  25                  30

Pro Lys Cys Ala Asp Phe Gln Ser Ala Asn Leu Phe Glu Gly Thr Asp
         35                  40                  45

Leu Lys Val Gln Phe Leu Leu Phe Val Pro Ser Asn Pro Ser Cys Gly
     50                  55                  60

Gln Leu Val Glu Gly Ser Ser Asp Leu Gln Asn Ser Gly Phe Asn Ala
 65                  70                  75                  80

Thr Leu Gly Thr Lys Leu Ile Ile His Gly Phe Arg Val Leu Gly Thr
                 85                  90                  95

Lys Pro Ser Trp Ile Asp Thr Phe Ile Arg Thr Leu Leu Arg Ala Thr
            100                 105                 110

Asn Ala Asn Val Ile Ala Val Asp Trp Ile Tyr Gly Xaa Thr Gly Val
        115                 120                 125

Tyr Phe Ser Ala Val Lys Asn Val Ile Lys Leu Ser Leu Glu Ile Ser
    130                 135                 140

Leu Phe Leu Asn Lys Leu Leu Val Leu Gly Val Ser Glu Ser Xaa Ile
145                 150                 155                 160

His Ile Ile Gly Val Ser Trp Gly Pro Thr Leu Gly Ala Trp Trp Asp
                165                 170                 175

Ser Phe Arg Arg Gln Ala Gly Thr Asp Xaa Arg Pro Glu Pro Ala 
            180                 185                 190



<210> 1429
<211> 101
<212> PRT
<213> Homo sapiens

<400> 1429
Met Glu Arg Pro Asp Lys Ala Ala Leu Asn Ala Leu Gln Pro Pro Glu
  1               5                  10                  15

Phe Arg Asn Glu Ser Ser Leu Ala Ser Thr Leu Lys Thr Leu Leu Phe
             20                  25                  30

Phe Thr Ala Leu Met Ile Thr Val Pro Ile Gly Leu Tyr Phe Thr Thr
         35                  40                  45

Lys Ser Tyr Ile Phe Glu Gly Ala Leu Gly Met Ser Asn Arg Asp Ser
     50                  55                  60

Tyr Phe Tyr Ala Ala Ile Val Ala Val Val Ala Val His Val Val Leu
 65                  70                  75                  80

Ala Leu Phe Val Tyr Val Ala Trp Asn Glu Gly Ser Arg Gln Trp Arg
                 85                  90                  95

Glu Gly Lys Gln Asp 
            100



<210> 1430
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1430
Met Ala Asn Thr Asn Phe Leu Ser Thr Leu Ser Pro Glu His Cys Arg
  1               5                  10                  15

Pro Leu Ala Gly Glu Cys Met Asn Lys Leu Lys Cys Gly Ala Ala Glu
             20                  25                  30

Ala Glu Ile Met Asn Leu Pro Glu Arg Val Gly Thr Phe Ser Ala Ile
         35                  40                  45

Pro Ala Leu Gly Gly Ile Ser Leu Pro Pro Gly Val Ile Val Met Thr
     50                  55                  60

Ala Leu His Ser Pro Ala Ala Ala Phe Ser Ser Arg Xaa Arg Gln Cys
 65                  70                  75                  80

Val Ser Asn Cys Gln Ser Gly Arg Leu Pro Ala Xaa Ser Phe Leu Leu
                 85                  90                  95

Leu Leu Val Leu Leu Arg Gly Ser Leu Xaa Xaa Gln Pro Gln Pro Arg
            100                 105                 110

Arg Arg Gly Lys Gly Xaa Gly Ser Ser Cys Pro Ala Arg 
        115                 120                 125



<210> 1431
<211> 177
<212> PRT
<213> Homo sapiens

<400> 1431
Met Lys Lys Lys Ala Lys Ile Gly Ile His His Lys Asn Ser Pro Pro
  1               5                  10                  15

Lys Val Thr Val Pro Thr Ser Gly Asn Thr Ile Glu Ser Pro Leu His
             20                  25                  30

Glu Asn Ile Ser Asn Ser Thr Ser Phe Lys Asp Glu Lys Ile Met Glu
         35                  40                  45

Thr Asp Ser Glu Pro Glu Glu Gly Glu Ile Thr Asp Ser Gln Thr Glu
     50                  55                  60

Asp Ser Tyr Asp Glu Ala Ile Thr Ser Glu Gly Asn Val Thr Ala Glu
 65                  70                  75                  80

Asp Ser Glu Asp Glu Asp Glu Asp Lys Ile Trp Pro Pro Cys Ile Arg
                 85                  90                  95

Val Ile Val Ile Arg Ser Pro Val Leu Gln Ile Gly Ser Leu Phe Ile
            100                 105                 110

Ile Thr Ala Val Asn Pro Ala Thr Ile Gly Arg Glu Lys Asp Met Glu
        115                 120                 125

His Thr Leu Arg Ile Pro Glu Val Gly Val Ser Lys Phe His Ala Glu
    130                 135                 140

Ile Tyr Phe Asp His Asp Leu Gln Ser Tyr Val Leu Val Asp Gln Gly
145                 150                 155                 160

Ser Gln Asn Gly Thr Ile Val Asn Gly Lys Thr Asp Ser Ser Ala Glu
                165                 170                 175

Asn 




<210> 1432
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1432
Met Ile Glu Gly Arg Gln Asp Leu Gly Ala Ser Ile Arg Pro Leu Thr
  1               5                  10                  15

Lys Ser Pro Arg Ser Gly Val Thr Ala Cys Ser Gly Gly Ala Glu Leu
             20                  25                  30

Pro Leu Leu Ile Phe His Leu His Pro Asp Arg Val Val Phe Pro Gln
         35                  40                  45

Thr Ala Ala Leu Arg Val Arg Ile Cys Gly Arg Phe His Leu Ile Xaa
     50                  55                  60

Gln Arg Thr Ser Tyr Phe Arg Thr Gly Asn Met Gly Pro Gly Gln Gly
 65                  70                  75                  80

Asp Tyr Phe Val Gly Cys Cys Gly Ile Leu Leu Leu Ile Lys Phe Thr
                 85                  90                  95

Gly Phe Val Leu Ile Xaa 
            100



<210> 1433
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1433
Met Gln Ala Glu Pro Glu Gln Ile Leu Gly Ser His Trp Arg Asp Leu
  1               5                  10                  15

Thr Val Val Thr Phe Leu Ile Ser Ser Ser Ser Phe Phe Pro Ser Leu
             20                  25                  30

Tyr Pro Ser Leu Phe Ser Gln Ser His Leu Glu Met Leu Glu Ser His
         35                  40                  45

Met Leu Ile Leu Val Leu Glu Arg Asn Tyr Arg Asp Phe Xaa Ser Pro
     50                  55                  60

Phe Leu Leu Pro Gly Ala Val Val Pro Leu Phe Leu Tyr Ile Pro Thr
 65                  70                  75                  80

Val Arg Lys Asn Gly Val Thr Glu Lys Trp Gly Thr Thr Phe Gly Gly
                 85                  90                  95

Ser Arg Ile Arg Thr Xaa Ile Leu Val Glu Tyr Pro 
            100                 105



<210> 1434
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1434
Met Glu Val Leu Ser Gly Glu Gln Asn Met Met Thr Lys Val Arg Glu
  1               5                  10                  15

Asn Asn Tyr Thr Tyr Glu Phe Asp Phe Ser Lys Val Tyr Trp Asn Pro
             20                  25                  30

Arg Leu Ser Thr Glu His Ser Arg Ile Thr Glu Leu Leu Lys Pro Gly
         35                  40                  45

Asp Val Leu Phe Xaa Val Phe Ala Gly Val Gly Pro Phe Ala Ile Pro
     50                  55                  60

Val Ala Lys Lys Asn Cys Thr Val Phe Ala Asn Asp Leu Asn Pro Glu
 65                  70                  75                  80

Ser His Lys Trp Leu Leu Tyr Asn Cys Lys Leu Asn Lys Val Asp Gln
                 85                  90                  95

Lys Val Lys Val Phe Asn Leu Gly Trp Glu Arg Leu Pro Pro Arg Thr
            100                 105                 110

Ser Gln Arg Arg Val Asn Ala Ala Ala Gly Ser Val Gln Lys Lys Glu
        115                 120                 125

Asn Pro Leu Cys Thr Xaa Ser 
    130                 135



<210> 1435
<211> 172
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1435
Met Ala Cys Ser Ile Tyr Val Met Gln Thr Leu Phe Tyr Leu Pro Phe
  1               5                  10                  15

Phe Ile Leu Gly Ala Leu Ala Phe Ile Phe Pro His Leu Lys Ala Leu
             20                  25                  30

Phe Thr Thr Pro Ser Arg Gly Cys Thr Leu Ala Ala Ala Leu Ala Phe
         35                  40                  45

Val Ala Tyr Leu Leu Asn Gln Arg Tyr Gly Ser Gly Asp Ala Trp Met
     50                  55                  60

Tyr Glu Thr Glu Ser Val Ile Thr Met Val Leu Gly Leu Trp Met Val
 65                  70                  75                  80

Asn Val Val Phe Ser Phe Gly His Arg Leu Leu Asn Phe Gln Ser Ala
                 85                  90                  95

Arg Val Thr Tyr Phe Val Asn Ala Ser Leu Phe Ile Tyr Leu Val His
            100                 105                 110

His Pro Leu Thr Leu Phe Phe Gly Ala Tyr Ile Thr Pro His Ile Thr
        115                 120                 125

Ser Asn Trp Leu Gly Phe Leu Cys Gly Leu Ile Phe Val Val Gly Ile
    130                 135                 140

Ala Ile Ile Leu Tyr Glu Ile His Leu Arg Ile Pro Leu Leu Lys Phe
145                 150                 155                 160

Leu Phe Ser Gly Lys Pro Val Pro Asn Ser Pro Xaa 
                165                 170



<210> 1436
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1436
Met Asn Met Ser Pro Val Ser Arg Leu Lys Lys Thr Trp Gly Gln Ser
  1               5                  10                  15

Glu Asp Gly Gln Val Phe His Pro Arg Ala Pro Asp Gly Pro Asn Gly
             20                  25                  30

Asn Phe Cys Asn Tyr Arg Thr Ala Leu Arg Gly Ala Ala His Arg Ser
         35                  40                  45

Leu Thr Ala His Ser Ser Arg Glu Lys Ile Val Ile Pro Phe Phe Ser
     50                  55                  60

Leu Leu Ile Lys Asp Ile Tyr Phe Leu Asn Glu Gly Cys Ala Asn Arg
 65                  70                  75                  80

Leu Pro Asn Gly His Val Asn Phe Glu Xaa Phe Leu Glu Leu Ala Lys
                 85                  90                  95

Gln Val Gly Glu Phe Ile Thr Trp Lys Gln Val Glu Cys Pro Phe Glu
            100                 105                 110

Gln Asp Ala Ser Ile Thr His 
        115



<210> 1437
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1437
Met Val Gln Ser Leu Lys Ser Met Glu Gly Ile Gln Val Glu Pro Ala
  1               5                  10                  15

Arg Lys Arg Thr Lys Gly Arg Thr Tyr Phe Cys Pro Ser Val Ser Leu
             20                  25                  30

Asn Gly Ala Ser Asn Gly Glu Ser Leu Arg His Gly Lys Ser Trp Asp
         35                  40                  45

Ser Leu Leu Val Leu Ile Pro Ala Thr Thr Ile Val Ala Thr Ile Asn
     50                  55                  60

Gln Val Ser Thr Cys His Thr Val Tyr Ile His Tyr Ser Leu Leu Pro
 65                  70                  75                  80

Ser Asn Ser Pro Val Cys Ala Tyr Phe Pro Ile Leu Pro Glu Gly Asn
                 85                  90                  95

Leu Arg Xaa Arg Arg Val Lys Cys Leu Gly Gln Gly Gln Lys Val Xaa
            100                 105                 110

Met Gly Asp Thr Gly 
        115



<210> 1438
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1438
Met Glu Leu Glu Asp Gly Val Val Tyr His Gly Gly Ala Arg Arg Leu
  1               5                  10                  15

Arg Gly Arg Asp Val Gly Ala Gly Val Arg Leu Ala Gly Ser Ile Tyr
             20                  25                  30

Arg Glu Phe Glu Arg Leu Ile Gly Arg Tyr Asp Glu Glu Val Val Lys
         35                  40                  45

Glu Leu Met Pro Leu Val Val Ala Val Leu Glu Xaa Leu Asp Ser Val
     50                  55                  60

Phe Ala Gln Asp Gln Glu His Gln Val Glu Leu Glu Leu Leu Arg Asp
 65                  70                  75                  80

Asp Asn Glu Gln Leu Ile Thr Gln Tyr Glu Arg Glu Lys Ala Leu Arg
                 85                  90                  95

Lys His Ala Glu Glu Lys Phe Ile Glu Phe Glu Asp Ser Gln Glu Gln
            100                 105                 110

Glu Lys Lys Asp Leu Gln Thr Arg Val Glu Ser Leu Glu Ser Gln Thr
        115                 120                 125

Arg Gln Leu Glu Leu Lys Ala Xaa Lys Leu Cys 
    130                 135



<210> 1439
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1439
Met Arg Cys Ser Gly Gly Cys Thr Trp Pro Asp Ser Pro Ser Cys Pro
  1               5                  10                  15

Val His Ser His Leu Pro Val Glu Arg Thr Leu Arg Val Pro Ser Pro
             20                  25                  30

Gly Leu Val Thr Cys Val Cys Ala Gly Ala Ala His Glu Asp Cys Leu
         35                  40                  45

Pro Leu Arg Ala Trp Ala Ala Ala Ala Ala Ile Leu Val Leu Gly Asn
     50                  55                  60

Gly Ala Ala Trp Xaa Ala Thr His Trp Cys Pro Val Ser Cys Arg Pro
 65                  70                  75                  80

Val Leu Pro Ile Ser Pro Lys Tyr His Ser Gln Phe Pro Asp Gly Pro
                 85                  90                  95

Gln Thr Gly Glu Glu Asn Gln Trp Pro Ser Gln Lys Leu Lys Gly 
            100                 105                 110



<210> 1440
<211> 230
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (162)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1440
Met Lys Leu Ser Leu Ser Pro Pro Pro Tyr Ala Asp Ala Pro Val Val
  1               5                  10                  15

Val Leu Ile Ser Gly Leu Gly Gly Ser Gly Ser Tyr Trp Leu Pro Gln
             20                  25                  30

Leu Ala Val Leu Glu Gln Glu Tyr Gln Val Val Cys Tyr Asp Gln Arg
         35                  40                  45

Gly Thr Gly Asn Asn Pro Asp Thr Leu Ala Glu Asp Tyr Ser Ile Ala
     50                  55                  60

Gln Met Ala Ala Glu Leu His Gln Ala Leu Val Ala Ala Gly Ile Glu
 65                  70                  75                  80

His Tyr Ala Val Val Gly His Ala Leu Gly Ala Leu Val Gly Met Xaa
                 85                  90                  95

Leu Ala Leu Asp Tyr Pro Ala Ser Val Thr Val Leu Ile Ser Val Asn
            100                 105                 110

Gly Trp Leu Arg Ile Asn Ala His Thr Arg Arg Cys Phe Gln Val Arg
        115                 120                 125

Glu Arg Leu Leu Tyr Ser Gly Gly Ala Gln Ala Trp Val Glu Ala Xaa
    130                 135                 140

Arg Cys Ser Ser Ile Pro Pro Thr Gly Trp Arg Pro Ala His Leu Ala
145                 150                 155                 160

Trp Xaa Gln Lys Thr Arg Trp His Trp Arg Ile Phe Arg Ala Lys Ile
                165                 170                 175

Ile Tyr Cys Val Asp Leu Thr Pro Ser Asn Ala Leu Thr Leu Val Thr
            180                 185                 190

Met Arg Ile Ala Ser Ala Ala Arg Cys Lys Ser Ser Ala Pro Val Met
        195                 200                 205

Ile Cys Trp Cys Gln Gln His Val Pro Val Asn Phe Met Pro Pro Cys
    210                 215                 220

Pro Ile Ala Arg Lys Trp 
225                 230



<210> 1441
<211> 213
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1441
Met Leu Xaa Val Glu Met Gly Gly Gly Cys Arg Gly Ser Met Gly Pro
  1               5                  10                  15

Gly Pro Gly Tyr Ser Ala Gly Ser Arg Val Cys Arg Gly Ser Ser Leu
             20                  25                  30

Pro Gln Val Ala Pro Phe Asn Pro Ser Arg Ala His Leu Leu Pro Pro
         35                  40                  45

Pro Val Gly Gly Gly Leu Asn Ser Val Trp Leu Ser Gly Val Gln Leu
     50                  55                  60

Ser Thr Pro Pro Tyr Ala Asp Trp Glu Gly Val Gly Gln Ser Pro Gln
 65                  70                  75                  80

Pro Arg Gly Pro Trp Met Gly Ser Ser Ser Leu Gly Thr Val Gly Pro
                 85                  90                  95

Gly Cys Val Leu Ser Gly Cys Pro Thr Val Lys Ala Asn Gly Gly Ser
            100                 105                 110

Pro Cys Ser Glu Met Leu Gly Glu Arg Arg Leu Leu Glu Pro Ser Val
        115                 120                 125

Gly Pro Val Ser Gly Cys Pro Glu Arg Arg Glu Gly Gly His Gly Ala
    130                 135                 140

Arg Gly Ala Ala Gly Val Val Val Lys Gly His Ala Ser Val Gln Leu
145                 150                 155                 160

Asn Phe Leu Ser Leu Ile Met Phe Tyr Pro Pro Cys Pro Phe Phe Pro
                165                 170                 175

Gln Leu Cys Phe Cys Ile Phe Phe Leu Gly Lys Cys Lys Leu Ser Leu
            180                 185                 190

Ser Phe Met Thr Cys Glu Ile Ser Val Ser Leu Glu Phe Val Arg Arg
        195                 200                 205

Arg Gly Asn His Ala 
    210



<210> 1442
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1442
Met Gly Gly Glu Gly Pro Phe Leu Pro Val Leu Thr Pro Thr Ser Val
  1               5                  10                  15

Lys Gly Thr Leu Tyr Lys Met Leu Arg Lys Pro Lys Lys Val Arg Val
             20                  25                  30

Gln Ala Ala Ser Cys Asp Leu Leu Arg Gly Leu Leu Val Ser Pro Leu
         35                  40                  45

Leu Leu Pro Val Arg Leu Leu Leu Ala Gly Trp Ala His Ala Trp Met
     50                  55                  60

His Gly Cys Gly Gly Trp Glu Pro Arg Ile Xaa Gln Gln Ser Ala Ser
 65                  70                  75                  80

Cys Gln Xaa Leu Ala Lys Gly Arg Asn Gln Gly Ser Thr Lys Ser Phe
                 85                  90                  95

Lys Xaa Lys Leu Glu Asp Ser 
            100



<210> 1443
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1443
Met Pro Ala Val Asn Ile Gln Tyr Glu Val Ile Asp Asn Ala Cys Val
  1               5                  10                  15

Leu Phe Ala Val Ser Val Leu Met Phe Ile Ile Ser Ser Met Leu Val
             20                  25                  30

Tyr Gly Ala Ile Ser Tyr Gln Val Gly Trp Leu Ile Pro Phe Phe Cys
         35                  40                  45

Tyr Arg Leu Phe Asp Phe Val Leu Ser Cys Leu Val Ala Ile Ser Ser
     50                  55                  60

Leu Thr Tyr Leu Pro Arg Ile Lys Glu Tyr Leu Asp Gln Leu Pro Asp
 65                  70                  75                  80

Phe Pro Tyr Lys Gly Trp Thr Ser Trp Ala Leu Gly Leu Gln Leu Pro
                 85                  90                  95

Pro Val Pro Leu Phe Leu Cys Ser Cys Leu Phe Ile Ile Leu Arg Xaa
            100                 105                 110

Ile 




<210> 1444
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1444
Met Thr Met Met Ile Val Phe Leu Ser Leu Ser Leu Ser Leu Tyr Ile
  1               5                  10                  15

Tyr Thr His Ile Tyr Thr His Ile Tyr Thr His Ile Tyr Ile His Ile
             20                  25                  30

Tyr Ile Tyr Thr Tyr Ile Tyr Ile Tyr Thr His Thr His Thr Tyr Ile
         35                  40                  45

Cys Phe Val Leu Leu Leu Phe Cys Phe Xaa Val Leu Arg Gln Gly Leu
     50                  55                  60

Val Leu Phe Pro Arg Ala Gly Ser Ala Val Thr Gln Ser Trp Ile His
 65                  70                  75                  80

Trp Gln Pro Trp Thr Ser Trp Val Phe Lys Leu Ala Ser Gln Leu Gln
                 85                  90                  95

Xaa Phe Pro Val Ala Xaa Gly 
            100



<210> 1445
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1445
Met Val Ser Ile Leu Cys Val Ser Tyr Cys Glu Glu Leu Gly Asp Thr
  1               5                  10                  15

Thr Leu Gln Asp Thr Met Val Lys Ser Gln Ile Thr Phe His Phe Leu
             20                  25                  30

Ser His His Tyr Leu Leu Leu His Ser Cys Pro Met Pro Phe Leu Ile
         35                  40                  45

Ile Trp Ile Tyr Val Ile Cys Val Ser Pro Phe Ser Cys Arg Glu Ser
     50                  55                  60

Pro Ser Ser Ser Ser Leu Met Gly Gly Phe Leu Ser Asp Met Phe Gln
 65                  70                  75                  80

Thr Ser Pro His Leu Arg Thr His Phe Leu His Arg Thr Ser Leu Leu
                 85                  90                  95

Ala Ser Leu Val Ala Arg Ala Leu Thr Val Leu Xaa Phe Leu Thr Pro
            100                 105                 110

Ser Gln Thr Ile Ser 
        115



<210> 1446
<211> 248
<212> PRT
<213> Homo sapiens

<400> 1446
Met Pro Thr Trp Ile Leu Val Leu Ser Leu Ser Leu Ala Gly Ala Leu
  1               5                  10                  15

Phe Leu Leu Ala Gly Leu Val Ala Val Ala Leu Val Val Arg Lys Val
             20                  25                  30

Lys Leu Arg Asn Leu Gln Lys Lys Arg Asp Arg Glu Ser Cys Trp Ala
         35                  40                  45

Gln Ile Asn Phe Asp Ser Thr Asp Met Ser Phe Asp Asn Ser Leu Phe
     50                  55                  60

Thr Val Ser Ala Lys Thr Met Pro Glu Glu Asp Pro Ala Thr Leu Asp
 65                  70                  75                  80

Asp His Ser Gly Thr Thr Ala Thr Pro Ser Asn Ser Arg Thr Arg Lys
                 85                  90                  95

Arg Pro Thr Ser Thr Ser Ser Ser Pro Glu Thr Pro Glu Phe Ser Thr
            100                 105                 110

Phe Pro Gly Leu Pro Val Arg Leu Arg Thr Gly Gly Pro Leu Cys Leu
        115                 120                 125

Gln Ala Phe Gly Gly Leu Arg Ser Leu Gln Leu Leu Leu Gly Gly Leu
    130                 135                 140

Cys Gln Pro Leu Ser Gln Gly Ile Gly Gln Arg Lys Gly Arg Gly Thr
145                 150                 155                 160

Leu Ala Leu Gly Phe Ser Ser Gln Arg Ser Gly Arg Gly Asp Thr Gly
                165                 170                 175

Met Gly Leu Ala Leu Tyr Arg Gln Gln Glu Val Pro Leu Ser Thr Ser
            180                 185                 190

Ala Pro Gln Asp His Gln Arg Arg Arg Cys Gln Asp Pro Phe Leu Ser
        195                 200                 205

Pro Ser Trp Ala Ile Arg Arg Pro Arg Ser Leu His Thr Arg Gly Ile
    210                 215                 220

Pro Pro Phe Pro Ser Gly Phe Leu Ser Ile Gly Cys Pro Trp Val Cys
225                 230                 235                 240

Cys Val Ser Ala Cys Trp Leu Ala 
                245



<210> 1447
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1447
Met Glu Lys Arg Thr Gly Thr Gly Gln Ala Leu Gly Glu Gly Gly Leu
  1               5                  10                  15

Pro Ser Ser His Gly Ala Pro Gly Thr Pro Ser Gly Thr Gly Arg Thr
             20                  25                  30

Ser Gly Arg Thr Asp Thr Val Ser Cys Glu Ile Val Phe Leu Leu Leu
         35                  40                  45

Phe Cys Val Xaa Ile Phe Phe Asn Phe Ser Leu Ser Val His Thr Thr
     50                  55                  60

Tyr Ser Ser Gly Thr Phe Phe Leu Cys Gln Ala Leu Asp Leu Glu Trp
 65                  70                  75                  80

Gly Pro Val Ser Asn Thr Val Glu Gly Glu Ala Asp Val Ser Val Met
                 85                  90                  95

Val Arg Ile Pro Lys Gly Ser Asp Lys 
            100                 105



<210> 1448
<211> 130
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1448
Met Thr Val Glu Asn Ile Asp Leu Lys Thr Ile Gly Phe Phe Ser Leu
  1               5                  10                  15

Val Gly Gln Ala Tyr Val Phe Lys Phe Leu Trp Ser Pro Leu Met Asp
             20                  25                  30

Arg Tyr Thr Pro Pro Phe Phe Gly Arg Arg Arg Gly Trp Leu Leu Ala
         35                  40                  45

Thr Gln Ile Leu Leu Leu Val Ala Ile Ala Ala Met Gly Phe Leu Glu
     50                  55                  60

Pro Gly Thr Gln Leu Arg Trp Met Ala Ala Leu Ala Val Val Ile Ala
 65                  70                  75                  80

Phe Cys Ser Ala Ser Gln Xaa Tyr Ser Leu Arg Cys Val Glu Asn Arg
                 85                  90                  95

Cys Ala Ser Gly Arg Arg Thr Trp Cys Gly Arg Gly Asn Gln Arg Ala
            100                 105                 110

Gly Leu Pro Phe Arg Asp Ala Gly Phe Arg Arg Pro Ser Pro Val Ala
        115                 120                 125

Gly Arg 
    130



<210> 1449
<211> 186
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1449
Met Ile Gln Glu Ala His Val Gly Ile Gly Ile Met Gly Lys Glu Gly
  1               5                  10                  15

Arg Gln Ala Ala Arg Asn Ser Asp Tyr Ala Ile Ala Arg Phe Lys Phe
             20                  25                  30

Leu Ser Lys Leu Leu Phe Val His Gly Pro Phe Tyr Tyr Ile Arg Ile
         35                  40                  45

Ala Thr Leu Val Gln Tyr Phe Phe Tyr Lys Asn Val Cys Phe Ile Thr
     50                  55                  60

Pro Gln Phe Leu Tyr Gln Phe Tyr Cys Leu Phe Ser Gln Gln Thr Leu
 65                  70                  75                  80

Tyr Asp Ser Val Tyr Leu Thr Leu Tyr Asn Ile Cys Phe Thr Ser Leu
                 85                  90                  95

Pro Ile Leu Ile Tyr Ser Leu Leu Glu Gln His Val Asp Pro His Val
            100                 105                 110

Leu Gln Asn Lys Pro Thr Leu Tyr Arg Asp Ile Ser Lys Asn Arg Leu
        115                 120                 125

Leu Ser Ile Lys Thr Phe Leu Tyr Trp Thr Ile Leu Gly Phe Ser His
    130                 135                 140

Ala Phe Ile Phe Phe Phe Gly Ser Tyr Leu Leu Ile Xaa Lys Asp Thr
145                 150                 155                 160

Ser Leu Leu Gly Asn Gly Gln Met Phe Gly Lys Leu Asp Ile Trp His
                165                 170                 175

Phe Gly Leu His Ser His Gly Tyr Tyr Ser 
            180                 185



<210> 1450
<211> 114
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1450
Met Gln Tyr Arg Ser Gly Asn Xaa Gly Xaa Thr His Ala Ser Gly Leu
  1               5                  10                  15

Xaa Leu Leu Arg Asp Ser Thr Ser Leu Leu Leu Lys Ala Ser Ser Asp
             20                  25                  30

Met Phe Val Phe Val Ile Xaa Ile Cys Ser Xaa Lys Ile Asp Leu Xaa
         35                  40                  45

Gly Asp Ser Leu Ser Ile Met His Ile Leu Cys Leu Leu Ser Arg Ile
     50                  55                  60

Leu Phe Thr Arg Asn Thr Ser Lys Gln Arg Lys Leu Tyr Leu His Glu
 65                  70                  75                  80

Pro Glu His Val Glu Met His Thr Met Tyr Thr Gly Asn Ala Val Ser
                 85                  90                  95

Ile Ser Gln Ser Leu Pro Ser Thr Ala Cys Val Val Ser Pro Ser His
            100                 105                 110

Leu Val 




<210> 1451
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (27)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1451
Met Ala Xaa Leu Pro Gly Leu Glu Gln Glu Trp Arg Gln Phe Leu Lys
  1               5                  10                  15

Thr Lys Val Ala Gly Gln Glu Lys Ile Ile Xaa Thr Pro Gln Lys Ile
             20                  25                  30

Met Gln Arg Lys His Arg Leu Glu Asp Ser Arg Ile Asp Leu Ser Ser
         35                  40                  45

Arg Arg Glu Ile Arg Glu Ser Met Lys Glu Glu Leu Ser Gly Thr Gly
     50                  55                  60

Ile Arg Asn Gln Lys Leu Ser Cys Leu Thr Leu Cys Glu Ser Thr Leu
 65                  70                  75                  80

Leu Ile Leu Leu His Leu Ser Ile Asn Phe Tyr Phe Ser Phe Ile Lys
                 85                  90                  95

Asn Ser Thr Leu Met Val Val Leu Leu Glu Pro Ile Ile Pro His Ser
            100                 105                 110

Leu Trp Met Arg Val Gly Gln Gly Lys Gln Asp Ile Leu 
        115                 120                 125



<210> 1452
<211> 127
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1452
Met Lys Arg Ser Cys Val Ser Cys Gly Leu Glu Pro Trp Glu Ser Gly
  1               5                  10                  15

Trp Glu Arg Val Gly Glu Ile Thr His Pro Trp Ala Trp Gly Glu Phe
             20                  25                  30

Pro Glu Met Val Leu Ala Ile Arg Met Tyr Lys Tyr Val Phe Thr His
         35                  40                  45

Ala Phe Ile Ser Leu Ser Thr Ser Ser Asp Gly Ser Ala Cys Val Leu
     50                  55                  60

Ser Ala Gly Ala Gly Ala Gly Cys Pro Leu Ala Cys Gln Phe Ala Leu
 65                  70                  75                  80

Phe Trp Thr Gly Pro Leu Ala Leu Cys Leu Xaa Ala Gly Arg Ala Glu
                 85                  90                  95

Arg Val Leu Ser Val Lys Glu Gly Leu Gly Pro Val Pro Ser Xaa Gln
            100                 105                 110

Ala Cys His Gly Xaa Val Val Phe Leu Leu Gly Leu Leu Thr Leu 
        115                 120                 125



<210> 1453
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1453
Met Pro Trp Ser Val Val Glu Ala Ser Thr Gln Leu Gly Pro Ser Thr
  1               5                  10                  15

Lys Val Leu His Gly Leu Tyr Asn Lys Val Ser Gln Phe Pro Glu Leu
             20                  25                  30

Thr Ser His Thr Met Arg Phe Asn Ala Phe Ile Leu Gly Leu Leu Asn
         35                  40                  45

Ile Arg Ser Leu Glu Phe Trp Phe Asn His Leu Tyr Asn His Glu Asp
     50                  55                  60

Ile Ile Gln Thr His Tyr Gln Pro Trp Gly Phe Leu Ser Ala Ala His
 65                  70                  75                  80

Thr Val Cys Pro Gly Leu Phe Glu Glu Leu Leu Leu Leu Leu Gln Pro
                 85                  90                  95

Leu Ala Leu Leu Ala Leu Gln Pro Arg Xaa Ala Val Pro Ala Pro Xaa
            100                 105                 110

Xaa Ala Lys Xaa Gly Ser Ser Ser Gly Xaa Thr Arg Asn Cys Cys Gly
        115                 120                 125

Val Val Pro Arg Asp Xaa Leu Val Val Leu 
    130                 135



<210> 1454
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1454
Met Cys Gly Tyr Glu Trp Ser Arg Leu Gly Val Gly Ile Gly Pro Arg
  1               5                  10                  15

Val Ala Ser Gln Ser Lys Ala Phe Arg Ser Arg Gly Ser Thr Leu Ser
             20                  25                  30

Asp Leu Thr Trp Ala Ala Lys Asp Lys Lys Pro Leu Ala Gln Glu Glu
         35                  40                  45

Glu Leu Ile Ser Gly Ser His Gln Gly Gly Trp Lys Val Arg Val Ser
     50                  55                  60

Arg Leu Phe Trp Asn Leu Gly Ala Val Gly Leu Val Arg Trp Leu Met
 65                  70                  75                  80

Leu Val Ile Pro Val Leu Trp Glu Ala Glu Ala Gly Gly Ser Leu Xaa
                 85                  90                  95

Ala Xaa Glu Phe Pro Glu Xaa Xaa Gly Gln His Ser Glu Ile Phe Val
            100                 105                 110

Tyr Lys Lys Lys Lys Lys Lys Lys Lys Lys Gly 
        115                 120



<210> 1455
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (27)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1455
Met Leu Pro Leu Ala Ala Val Arg Ile Cys Leu Pro His Gln Pro Gly
  1               5                  10                  15

Pro Gln Ala Lys Ser Ser Ala Ser Ala Leu Xaa Gln Leu Pro Ala Asn
             20                  25                  30

Gln Lys Leu Thr Val Ile Pro Lys Met Phe Leu Ser Pro Gly Thr Pro
         35                  40                  45

Ala Pro Lys Ile Phe Ser Ser Phe Pro Gln Thr Ser Phe Lys Gly Gly
     50                  55                  60

Met His Asn Ser Val Leu Glu Arg Thr Val Val Gly Phe Leu Asp Phe
 65                  70                  75                  80

Arg His Ile Tyr Phe Pro Val Met Glu Ile Cys Phe Ile Leu Ile Ser
                 85                  90                  95

Tyr Leu Phe Phe Ile Leu Cys Phe Cys Ile Xaa Leu Ile Asn Pro Phe
            100                 105                 110

Trp Ser Leu 
        115



<210> 1456
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1456
Met Arg Xaa Tyr Met Val Leu Ala Ala His Phe Gln Arg Thr Thr Glu
  1               5                  10                  15

Glu Thr Glu Gly Leu Thr Cys Gln Val Cys Gln Met Leu Leu Pro Asn
             20                  25                  30

Gln Cys Ser Phe Cys Ala His Gln Arg Xaa Ser Cys Thr Gln Val Pro
         35                  40                  45

Leu Leu Leu Pro Gly Val Trp Gly Pro Leu Pro Leu Cys Leu Leu Xaa
     50                  55                  60

Asp Pro Cys Lys Gly Glu Leu Pro Ala Leu Cys Pro Gln Gly Gly Leu
 65                  70                  75                  80

Gln Val His Pro Leu Trp Cys Arg Pro Pro Asp Leu Gly Leu Ala Glu
                 85                  90                  95

Lys Ala His Pro Gly Ala Thr 
            100



<210> 1457
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1457
Met Gln Leu Glu Ala Arg Gly Thr Pro Thr Asn Pro Ser Ser Asp Ser
  1               5                  10                  15

Phe Gln Gly Ser Ile Ser Leu Arg Asn Leu Ile Arg Lys Val Thr Xaa
             20                  25                  30

Val Phe Xaa Lys Ser Pro Leu Tyr Pro Pro Ile Pro Ala Leu Pro Thr
         35                  40                  45

Thr Ala Ser Cys Ile Pro Ala Thr Thr Pro Phe Ser Lys Ser Ile Phe
     50                  55                  60

Ile His Leu Leu Phe Trp Ser Val Ala Leu Ile Pro Thr Ile Glu Cys
 65                  70                  75                  80

Thr Glu Thr Ala Gln Trp Leu Val Arg Leu Val Asn Asn Asp Thr Trp
                 85                  90                  95

Trp Ile Asn Val Thr Phe 
            100



<210> 1458
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1458
Met Arg Gln Met Gly Pro Ser Leu Leu Lys Ser Leu Gly Arg Leu Ile
  1               5                  10                  15

Ser Cys Leu Ser Cys Gln Thr Arg Glu Ser Arg Gly Val Tyr Thr Leu
             20                  25                  30

Tyr Lys Leu Phe Ser His Arg Gly Cys Leu Ser Phe Leu Pro Pro Cys
         35                  40                  45

Phe Val Ala Ser Leu Pro Pro Phe Leu Thr Ser Leu Pro Phe Pro Pro
     50                  55                  60

Pro Cys Pro His Pro Phe Leu Pro Leu Pro Leu Phe Val Ser Leu Ser
 65                  70                  75                  80

Phe Ile Leu Ser Cys Pro Pro Ala Tyr Phe Pro Ala Ser Phe Pro Leu
                 85                  90                  95

Pro Leu Val Leu Gly Leu Phe Ser Val Ala Val Thr Thr Asp Trp Asp
            100                 105                 110

Asn Gly Ile Asn Phe Lys Glu Lys Arg Ile Tyr Arg Trp Gly Trp Val
        115                 120                 125

Gly Leu Met Val Ser Lys Ser Gln Xaa 
    130                 135



<210> 1459
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1459
Met Leu Arg Ala Leu Ser Pro Ser Leu Phe Ser Thr Val Leu Gln Pro
  1               5                  10                  15

Cys Gln Arg Cys Thr Cys Glu Phe Lys Thr Ala Leu Arg His Ile Gly
             20                  25                  30

Tyr Ile Gly Thr Arg Lys Pro Lys Gln Tyr Phe His Asp Gln Ile Leu
         35                  40                  45

Ser Glu Phe Asn Thr Lys Gly Gly Lys Gly Asn Val Leu Cys Ser Leu
     50                  55                  60

Tyr Arg Phe Leu Phe Cys Leu Leu Gly Phe Tyr Lys Val Leu Leu Ile
 65                  70                  75                  80

Phe Met Cys Asp Trp Xaa Asn Ala Val Leu Val Lys Leu Leu Lys Thr
                 85                  90                  95

Leu Thr Xaa Leu 
            100



<210> 1460
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1460
Met Cys Val Arg Lys Lys Glu Xaa Gly Ala Leu Tyr Ser Lys Gly Lys
  1               5                  10                  15

Ser Tyr Trp Ser Leu Phe Glu Asn Lys Ser Val Val Thr Cys Val Ile
             20                  25                  30

Cys Lys Trp His Val Leu Ile His Ile Phe Phe Leu Ile Asn Ser Gly
         35                  40                  45

Ser Ala Leu Ser His Ala Cys Phe Cys Tyr Ala Leu Ile Cys Ser Ile
     50                  55                  60

Pro Val Xaa Thr Tyr Ile Val Leu Val Thr Ser Leu Arg Tyr His Leu
 65                  70                  75                  80

Phe Ile Trp Ser Val Phe Ser Pro Lys Leu Leu Tyr Glu Gly Met His
                 85                  90                  95

Leu Leu Ile Thr Ala Ala Val Cys Val Phe Phe Xaa Ala Met Gly Gln
            100                 105                 110

Thr Arg Leu Thr Gln Ser 
        115



<210> 1461
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1461
Met Leu Arg Val Arg Gly Asp Leu Thr Gln His Leu Thr Asp Thr Thr
  1               5                  10                  15

Gln Gly Met Arg Glu Val Leu Gly Phe Gly Tyr Gly Asp Arg Arg Leu
             20                  25                  30

Ala Glu Thr Asp Arg Ile Ser Glu Glu Val Gly Asn Ala Ala Phe Ala
         35                  40                  45

Asn Arg Leu Thr Ser Gly Ile Arg Arg Ser Leu Cys Glu Gly Leu Arg
     50                  55                  60

Leu Phe Ala Val Val Thr Thr Val Leu Val Gly Ala Asp Ala Val Arg
 65                  70                  75                  80

Arg Gly Asp Leu Ser Ile Pro His Leu Ala Ile Cys Ala Thr Val Ala
                 85                  90                  95

Leu Gly Val Phe Thr Pro Ala Arg Gly Thr Glu Asp Phe Ala Asp Asp
            100                 105                 110

Leu Glu Arg Ser Phe Ala Ala Ala Glu Arg Met Ser Val Ile Lys Tyr
        115                 120                 125

Arg Glu Pro Pro Xaa Ala Arg Gly Ile His 
    130                 135



<210> 1462
<211> 106
<212> PRT
<213> Homo sapiens

<400> 1462
Met Lys Met Thr Arg Ser Lys Met Pro Ser Leu Arg Thr Ser Pro Leu
  1               5                  10                  15

Ser Leu Thr Gln Lys Gly Lys Ser Leu Val Arg Arg Val Lys Ala Lys
             20                  25                  30

Lys Pro Arg Ser Leu Lys Asn Gln Glu Phe Gly Arg Ser Arg Asp Pro
         35                  40                  45

Ser Pro Asp Gly Arg Arg Ser Phe Val Val Arg Gly Asp Ala Cys Asn
     50                  55                  60

Ala Arg Leu Ala Leu Pro Val Gly Ala Gly Ala Pro Cys Met Leu Phe
 65                  70                  75                  80

Ile Ala Gly Arg Ser Phe Pro Pro Ser Thr Ser Val Leu Thr Arg Ala
                 85                  90                  95

Ala Arg Pro Cys Thr Glu Ala Leu Thr Ala 
            100                 105



<210> 1463
<211> 110
<212> PRT
<213> Homo sapiens

<400> 1463
Met Gly Asn Pro Glu Pro Leu Thr His Ala Pro Arg Lys Val Tyr Asp
  1               5                  10                  15

Thr Arg Asp Asp Asp Arg Thr Pro Gly Leu His Gly Asp Cys Asp Asp
             20                  25                  30

Asp Lys Tyr Arg Arg Arg Pro Ala Leu Gly Trp Leu Ala Arg Leu Leu
         35                  40                  45

Arg Ser Arg Ala Gly Ser Arg Lys Arg Pro Leu Thr Leu Leu Gln Arg
     50                  55                  60

Ala Gly Leu Leu Leu Leu Leu Gly Leu Leu Gly Phe Leu Ala Leu Leu
 65                  70                  75                  80

Ala Leu Met Ser Arg Leu Gly Arg Ala Ala Ala Asp Ser Asp Pro Asn
                 85                  90                  95

Leu Asp Pro Leu Met Asn Pro His Ile Arg Val Gly Pro Ser 
            100                 105                 110



<210> 1464
<211> 118
<212> PRT
<213> Homo sapiens

<400> 1464
Met Cys Leu Phe Leu Ala Cys Asp Phe Ala Leu Gly Leu Met Ile Asn
  1               5                  10                  15

Tyr Phe Gln Ile Gln Ser Ala Leu Val Leu Pro Gln Ser Asn Gln Lys
             20                  25                  30

Tyr Val Gly Gly Asn Gln Pro Asp Pro Gly Pro Phe Phe Phe Ser Ile
         35                  40                  45

Phe Ile Arg Asn Pro Pro Gln Gln Ile Phe Thr Ser Ser Phe Leu Ile
     50                  55                  60

Ala His Val Ser Leu Gly Leu Cys Leu Pro Ser Thr Val Gln Asn Thr
 65                  70                  75                  80

Leu Trp Phe Leu Phe Ser Leu Thr Phe Cys Gly Ala Val Lys Arg Ala
                 85                  90                  95

Gln Arg His Asn Gln Leu Lys Arg Lys Asn Pro Pro Met Asp Leu Tyr
            100                 105                 110

Gln Leu Asn Thr Asn Asn 
        115



<210> 1465
<211> 148
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1465
Met Thr Ile Trp Leu Gly Ile Val Tyr Ala Tyr Lys Gly Leu Leu Met
  1               5                  10                  15

Leu Phe Gly Cys Phe Leu Ala Trp Glu Thr Arg Asn Val Ser Ile Pro
             20                  25                  30

Ala Leu Asn Asp Ser Lys Tyr Ile Gly Met Ser Val Tyr Asn Val Gly
         35                  40                  45

Ile Xaa Cys Ile Ile Gly Ala Ala Val Ser Phe Leu Thr Arg Xaa Pro
     50                  55                  60

Ala Gln Cys Ala Val Leu His Arg Gly Ser Gly His His Leu Leu Gln
 65                  70                  75                  80

His His His Pro Leu Pro Gly Ile Arg Ala Glu Ala His His Pro Glu
                 85                  90                  95

Glu Gln Thr Gln Met Gln Gln Arg Xaa Asn Arg Arg Phe Gln Phe His
            100                 105                 110

Phe Arg Ile Gln Lys Glu Arg Arg Phe Leu Lys Arg Pro Pro Ser Gly
        115                 120                 125

Ser Pro Cys Glu Thr Gln Ala Xaa Thr Ser Arg Leu Gly Gly Pro Tyr
    130                 135                 140

Ile Gln Lys Thr 
145



<210> 1466
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1466
Met Cys Lys Leu Ile Val Ala Ile Asp Gln Tyr Asn Thr Phe Ser Ser
  1               5                  10                  15

Leu Tyr Phe Leu Thr Val Met Ser Ala Asp Arg Tyr Leu Val Val Leu
             20                  25                  30

Ala Thr Ala Glu Ser Arg Arg Val Ala Gly Arg Thr Tyr Ser Ala Ala
         35                  40                  45

Arg Ala Val Xaa Ala Trp Ala Val Trp Gly Ile Val Thr Leu Val Val
     50                  55                  60

Leu Pro Phe Arg Xaa Leu Ser Pro Gly Xaa Asp Glu Glu Gln Gly Arg
 65                  70                  75                  80

Arg Gln Cys Val Leu Ile Phe Ser Gly Asn Pro Lys Ala Phe Trp Leu
                 85                  90                  95

Ala Arg Xaa Arg Phe Leu Lys Gly Ser Ala Gly Val Cys Asn Pro Arg
            100                 105                 110

Cys Ser Asn Xaa 
        115



<210> 1467
<211> 155
<212> PRT
<213> Homo sapiens

<400> 1467
Met Val Ser Val Pro Leu Arg Met Val Pro Glu Val Leu Arg Ser Ser
  1               5                  10                  15

Tyr Thr Gln Gln Gly His His Pro Leu Leu Val Cys Pro Trp Leu Cys
             20                  25                  30

Ala Glu Gly Pro Gly Gln His Gln Val Cys Ala Trp Ala Pro Ser His
         35                  40                  45

Trp Ser Asp Pro Pro Pro Ile Cys Arg Ala Ala Ser Leu Asp Gly Phe
     50                  55                  60

Tyr Asn Ser Arg Ser Leu Asp Val Ala Lys Ala Pro Ala Ala Ser Ser
 65                  70                  75                  80

Thr Leu Asp Ala Ala His Ile Ala Ala Ala Ile Phe Leu Pro Leu Val
                 85                  90                  95

Ala Met Val Leu Leu Val Gly Gly Val Tyr Phe Tyr Phe Ser Arg Leu
            100                 105                 110

Gln Gly Lys Ser Ser Leu Gln Leu Pro Arg Pro Arg Pro Arg Pro Tyr
        115                 120                 125

Asn Arg Ile Thr Ile Glu Ser Ala Phe Asp Asn Pro Thr Tyr Glu Thr
    130                 135                 140

Gly Ser Leu Ser Phe Ala Gly Asp Glu Arg Ile 
145                 150                 155



<210> 1468
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1468
Met Met Thr Leu Xaa Ser Thr Ala Leu Ile Pro Gly Leu Thr His Gly
  1               5                  10                  15

Ala Gly Arg Trp Val Met Glu Gln Gly Pro Ser Gln Pro Ser His Leu
             20                  25                  30

Leu Gly Asn Ser Arg Leu Thr Met Gln Arg Val His Ala Cys Asp Phe
         35                  40                  45

Cys Phe Leu Val Trp Asn Arg Thr Lys Glu His Glu Asp Ile Trp Ile
     50                  55                  60

Phe Phe Leu Pro Leu Leu His Val Tyr Ile Gly Val Cys Pro Lys Ser
 65                  70                  75                  80

Leu Leu Leu Gln Asp Gly Val Glu Ile Asn Thr His Ala Glu Leu Cys
                 85                  90                  95

Pro Leu Gln Pro His Ser Thr Cys Ala Ser Ser Cys Val Leu Thr Gly
            100                 105                 110

Glu Cys Arg 
        115



<210> 1469
<211> 117
<212> PRT
<213> Homo sapiens

<400> 1469
Met Ser Ala Glu Val Lys Val Thr Gly Gln Asn Gln Glu Gln Phe Leu
  1               5                  10                  15

Leu Leu Ala Lys Ser Ala Lys Gly Ala Ala Leu Ala Thr Leu Ile His
             20                  25                  30

Gln Val Leu Glu Ala Pro Gly Val Tyr Val Phe Gly Glu Leu Leu Asp
         35                  40                  45

Met Pro Asn Val Arg Glu Leu Ala Glu Ser Asp Phe Ala Ser Thr Phe
     50                  55                  60

Arg Leu Leu Thr Val Phe Ala Tyr Gly Thr Tyr Ala Asp Tyr Leu Ala
 65                  70                  75                  80

Glu Ala Arg Asn Leu Pro Pro Leu Thr Glu Ala Gln Lys Asn Lys Leu
                 85                  90                  95

Arg His Leu Ser Val Val Thr Leu Ala Ala Lys Val Lys Cys Ile Pro
            100                 105                 110

Tyr Ala Val Leu Leu 
        115



<210> 1470
<211> 144
<212> PRT
<213> Homo sapiens

<400> 1470
Met Pro Asn Arg Ala Ile Arg Leu Gln Ala Val Leu Glu Ile Ile Thr
  1               5                  10                  15

Asn Gln Thr Ala Ser Ala Leu Glu Met Leu Ala Gln Gln Gln Asn Gln
             20                  25                  30

Met Arg Ala Ala Ile Tyr Gln Asn Arg Leu Ala Leu Asp Tyr Leu Leu
         35                  40                  45

Ala Glu Glu Gly Ala Gly Cys Gly Lys Phe Asn Ile Ser Asn Cys Cys
     50                  55                  60

Leu Asn Ile Gly Asn Asn Gly Glu Glu Val Leu Glu Ile Ala Ser Asn
 65                  70                  75                  80

Ile Arg Lys Val Ala Arg Val Pro Val Gln Thr Trp Glu Gly Trp Asp
                 85                  90                  95

Pro Ala Asn Leu Leu Gly Gly Trp Phe Ser Asn Leu Gly Gly Phe Lys
            100                 105                 110

Met Leu Val Gly Thr Val Ile Phe Ile Thr Gly Val Leu Leu Phe Leu
        115                 120                 125

Pro Cys Gly Ile Pro Leu Lys Leu Leu Leu Lys Leu Gln Leu Thr Ser
    130                 135                 140






<210> 1471
<211> 158
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1471
Met Gln Ala Pro Ala Phe Arg Asp Lys Lys Gln Gly Val Ser Ala Lys
  1               5                  10                  15

Asn Gln Gly Ala His Asp Pro Asp Tyr Glu Asn Ile Thr Leu Ala Phe
             20                  25                  30

Lys Asn Gln Asp His Ala Lys Gly Gly His Ser Arg Pro Thr Ser Gln
         35                  40                  45

Val Pro Ala Gln Cys Arg Pro Pro Ser Asp Ser Thr Gln Val Pro Cys
     50                  55                  60

Trp Leu Tyr Arg Ala Ile Leu Ser Leu Tyr Ile Leu Leu Ala Leu Ala
 65                  70                  75                  80

Phe Val Leu Cys Ile Ile Leu Ser Ala Phe Ile Met Val Lys Asn Ala
                 85                  90                  95

Glu Met Ser Lys Glu Leu Leu Gly Phe Lys Arg Glu Leu Trp Asn Val
            100                 105                 110

Ser Asn Ser Val Gln Ala Cys Glu Glu Arg Gln Lys Arg Gly Trp Xaa
        115                 120                 125

Ser Val Gln Gln Ser Ile Thr Met Val Arg Ser Lys Ile Asp Arg Leu
    130                 135                 140

Glu Thr Thr Leu Ala Gly Ile Lys Asn Ile Asp Thr Lys Val 
145                 150                 155



<210> 1472
<211> 102
<212> PRT
<213> Homo sapiens

<400> 1472
Met Leu Glu His Leu Ser Ser Leu Pro Thr Gln Met Asp Tyr Lys Gly
  1               5                  10                  15

Gln Lys Leu Ala Glu Gln Met Phe Gln Gly Ile Ile Ile Phe Ser Ala
             20                  25                  30

Ile Val Gly Phe Ile Tyr Gly Tyr Val Ala Glu Gln Phe Gly Trp Thr
         35                  40                  45

Val Tyr Ile Val Met Ala Gly Phe Ala Phe Ser Cys Leu Leu Thr Leu
     50                  55                  60

Pro Pro Trp Pro Ile Tyr Arg Arg His Pro Leu Lys Trp Leu Pro Val
 65                  70                  75                  80

Gln Asp Ser Gly Ser Glu Asp Lys Lys Pro Gly Glu Arg Lys Ile Lys
                 85                  90                  95

Arg His Ala Lys Asn Asn 
            100



<210> 1473
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (46)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1473
Met Gly Pro Pro Arg Ala Pro Val Trp Arg Met Pro Arg Gly Thr Leu
  1               5                  10                  15

Val Cys Gly Thr Gly Ser Lys Ser Leu Gly Ile Arg Gly Ile Arg Ala
             20                  25                  30

Phe Gln Leu Gln Leu Pro Asp Glu Arg Ala Val Phe Thr Xaa Pro Thr
         35                  40                  45

Leu Arg Pro Ser Pro Ser Lys Ala Gly Pro Ser Ala Trp Pro Ala Leu
     50                  55                  60

Thr Thr Ser Ser Lys Ala Leu Arg Ser Trp Gln Gly Ser Ser Glu Ala
 65                  70                  75                  80

Leu Asp Glu Asp Val Glu Ser Ser Val Leu Pro Leu Pro Leu Thr Ser
                 85                  90                  95

Ala Arg Gly Ser Pro Gly Cys Cys Leu Ala Gln Asp Leu Gly Gln Trp
            100                 105                 110

Pro Cys Leu Cys Pro Pro His Pro Pro Ala Leu Gly Thr Xaa Gln Ala
        115                 120                 125

Val Leu Gly Val Asp Thr Met Lys His Arg Leu His Lys Thr Pro Phe
    130                 135                 140

Gly Glu Val Val Val His Ile Leu Phe Phe Phe Asp Leu Cys Glu Phe
145                 150                 155                 160

Lys Val Asn Thr Thr Thr Val Asp Asn Ser 
                165                 170



<210> 1474
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1474
Met Gln Asn Ser Asn Leu Thr Ser Gly Ala Cys Gln Ile Ser Asn Gly
  1               5                  10                  15

Ser Leu Ser Pro Glu Arg Pro Val Gly Glu Thr Ser Phe Ser Val Pro
             20                  25                  30

Leu His Pro Thr Lys Arg Pro Ala Ser Asn Pro Pro Pro Ile Ser Asn
         35                  40                  45

Gln Ala Thr Lys Gly Lys Arg Pro Lys Lys Gly Met Ala Thr Ala Lys
     50                  55                  60

Gln Arg Leu Gly Lys Ile Leu Lys Leu Asn Arg Asn Gly His Ala Arg
 65                  70                  75                  80

Phe Phe Val Leu Thr Glu Leu Ala Val Ala Ala Ile Leu Pro Phe Gly
                 85                  90                  95

Asp Gln Ser Arg Gly Ala Gly Ala Trp Glu Leu Pro Leu Ser Pro Cys
            100                 105                 110

Leu Glu Gln Phe Val Cys Xaa Ser 
        115                 120



<210> 1475
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1475
Met Ile Pro Leu Cys Trp Val Leu Gly Asp Gly Gly Met Asp Cys Met
  1               5                  10                  15

Thr Ser Gln Lys Ser Leu Gly Thr Arg Thr Pro Ser Leu Ser Cys Gly
             20                  25                  30

Leu Pro His Pro Ser Leu Ser His Gly Ser Gly Arg Gly Ile Ser Lys
         35                  40                  45

Val Leu Cys Ser Leu Gly Thr Val Ser Arg Ile Leu Leu Cys Ser Pro
     50                  55                  60

Gln Pro Ser Ala Gly Ile Val Arg Xaa Gly Gly Lys Arg Arg Arg Arg
 65                  70                  75                  80

Gln Asp Trp Lys Arg Pro Gly Gly Lys Glu Leu Ser Val His Pro Ser
                 85                  90                  95

Leu Leu Leu Phe Leu Leu Ala Met Trp Pro Ser Phe Ile Leu Pro 
            100                 105                 110



<210> 1476
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1476
Met Val Val Glu Arg Arg Ser Gln Ser Glu Met Leu Asn Ser Val Asn
  1               5                  10                  15

Lys Xaa Lys Phe Xaa Glu Gln Ile Gln His Leu Gln Ser Met Phe Glu
             20                  25                  30

Arg Ile Cys Val Ile Val Glu Lys Asp Arg Glu Lys Thr Gly Asp Thr
         35                  40                  45

Ser Arg Met Phe Arg Arg Thr Lys Xaa Tyr Asp Ser Leu Leu Thr Thr
     50                  55                  60

Leu Ile Gly Ala Gly Ile Arg Ile Leu Phe Xaa Ser Cys Gln Glu Glu
 65                  70                  75                  80

Thr Ala Asp Leu Leu Lys Glu Xaa Ser Leu Val Glu Gln Arg Lys Asn
                 85                  90                  95

Leu Thr Ser Arg Asn Leu His Val Cys Thr Ser Asn Ser Ser Glu Gly
            100                 105                 110






<210> 1477
<211> 213
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (203)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (206)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1477
Met Leu Tyr Phe Val Leu Gly Ala Leu Ser Tyr Ile Leu Lys Trp Pro
  1               5                  10                  15

Ala Leu Asn Glu Asp Pro Ile Thr Lys Thr Ile Ala Ala Leu Ile Ile
             20                  25                  30

Leu Trp Ala Leu Ala Leu Thr Gln Phe Gly Gly Thr Lys Tyr Thr Ala
         35                  40                  45

Arg Ile Ala Lys Val Gly Phe Phe Ala Gly Ile Leu Leu Pro Ala Phe
     50                  55                  60

Ile Leu Ile Ala Leu Ala Ala Ile Tyr Leu His Ser Gly Ala Pro Val
 65                  70                  75                  80

Ala Ile Glu Met Asp Ser Lys Thr Phe Phe Pro Asp Phe Ser Lys Val
                 85                  90                  95

Gly Thr Leu Val Val Phe Val Ala Phe Ile Leu Ser Tyr Met Gly Val
            100                 105                 110

Glu Ala Ser Ala Thr His Val Asn Glu Met Ser Asn Pro Gly Arg Asp
        115                 120                 125

Tyr Pro Leu Ala Met Leu Leu Leu Met Val Ala Ala Ile Cys Leu Ser
    130                 135                 140

Ser Val Gly Gly Leu Ser Ile Ala Met Val Ile Pro Gly Asn Glu Ile
145                 150                 155                 160

Asn Leu Ser Ala Gly Val Met Gln Thr Phe Thr Val Leu Met Ser His
                165                 170                 175

Val Ala Pro Glu Ile Glu Trp Thr Val Arg Val Ile Ser Ala Leu Leu
            180                 185                 190

Leu Arg Val Val Xaa Arg Lys Ile Pro Ser Xaa Ile Val Xaa Val Pro
        195                 200                 205

Pro Pro Arg Glu Cys 
    210



<210> 1478
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1478
Met Gln Ser Val Ile Ala Leu Leu Ser Asn Leu Val Ala Cys Lys Asp
  1               5                  10                  15

Ser Asn Met Glu Leu Leu Tyr Glu Gln Gly Leu Val Ser His Ile Cys
             20                  25                  30

Asn Leu Leu Thr Glu Thr Ala Thr Leu Cys Leu Asp Val Asp Asn Lys
         35                  40                  45

Asn Asn Asn Glu Met Ala Ala Pro Leu Leu Phe Ser Leu Leu Asp Ile
     50                  55                  60

Leu His Ser Met Leu Thr Tyr Thr Ser Gly Ile Val Arg Leu Ala Leu
 65                  70                  75                  80

Gln Ala Gln Lys Ser Gly Ser Gly Glu Asp Pro Gln Ala Ala Glu Asp
                 85                  90                  95

Leu Leu Leu Leu Asn Arg Pro Leu Asp Arg Pro Asp Xaa Ala Cys Ser
            100                 105                 110

Phe Pro Leu Leu Ser 
        115



<210> 1479
<211> 173
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1479
Met Val His Cys Pro His Glu Leu Leu Gln Met Pro Leu Ser Leu Phe
  1               5                  10                  15

Ser Gln Arg Ser Trp Val Thr Gln Cys Leu Asp Thr Trp Lys Thr Cys
             20                  25                  30

Thr Leu Ile Thr Gln Arg His Leu Ala Ser Asp His Leu Pro Ser Glu
         35                  40                  45

Phe Leu Leu Val Gln Leu Val Thr Leu Leu Phe His Leu Phe Leu Arg
     50                  55                  60

Asp His Leu His Leu Phe Gln Pro Leu Leu Pro His Gln Arg Trp Ala
 65                  70                  75                  80

Asn Gln Lys Glu Ser Val Pro Val Lys Ile Glu Arg Tyr Leu Pro Gln
                 85                  90                  95

Leu Glu Gln Arg Asp Trp Pro Glu Phe Gly Lys Glu Gly Leu Leu His
            100                 105                 110

Lys Pro Arg Arg Gly Thr Ser Phe Val Xaa Pro Val Gly His Xaa Gly
        115                 120                 125

Ile Trp Phe Ile Trp Cys Gln Cys Cys Val Arg Arg Leu Ile Arg Leu
    130                 135                 140

Val Ala Ile Cys Asp Gly Glu His Pro Met His Gln His Xaa Arg Thr
145                 150                 155                 160

Gln Gln Ile Leu Pro Asn Gln Xaa Trp Arg Lys Met Ile 
                165                 170



<210> 1480
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1480
Met Gly Gln Ile Ile Gln Tyr Asp Lys Phe Tyr Ile His Glu Val Gln
  1               5                  10                  15

Glu Leu Ile Asp Ile Xaa Asn Asp Tyr Ile Asn Trp Val Gln Gln Gln
             20                  25                  30

Ala Tyr Gly Met Leu Ala Asp Ile Pro Val Thr Ile Cys Thr Tyr Pro
         35                  40                  45

Phe Val Phe Asp Ala Gln Ala Lys Thr Thr Leu Leu Gln Thr Asp Ala
     50                  55                  60

Val Leu Gln Met Gln Met Ala Ile Asp Gln Ala His Arg Gln Asn Xaa
 65                  70                  75                  80

Ser Xaa Leu Phe Leu Pro Val Ile Glu Ser Val Asn Pro Cys Leu Ile
                 85                  90                  95

Leu Val Val Arg Arg Glu Asn Ile Val Gly Asp Ala Met Glu Val Leu
            100                 105                 110

Arg Lys Gln Arg His Xaa Leu Gln Glu Ala Thr Gln Gly Tyr Ile Phe
        115                 120                 125

Leu Xaa Gly Ala Leu Val Gln Xaa Gly Ala Gln Glu Phe Ser Cys Ser
    130                 135                 140

Ser Trp Gly Ile Ile Gly 
145                 150



<210> 1481
<211> 258
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (222)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1481
Met Pro Gly Leu Asp Pro Asn Leu Arg Ser Ala Val Ser Ile Ala Arg
  1               5                  10                  15

Arg Val Gln Asp Pro Leu Ala Glu Leu Val Lys Ile Glu Pro Lys His
             20                  25                  30

Ile Gly Val Gly Met Tyr Gln His Asp Val Ser Gln Thr Leu Leu Lys
         35                  40                  45

Ala Thr Leu Asp Ser Val Val Glu Glu Cys Val Ser Phe Val Gly Val
     50                  55                  60

Asp Ile Asn Ile Cys Ser Glu Val Leu Leu Arg His Ile Ala Gly Leu
 65                  70                  75                  80

Asn Ala Asn Arg Ala Lys Asn Ile Ile Glu Trp Arg Glu Lys Asn Gly
                 85                  90                  95

Pro Phe Ile Asn Arg Glu Gln Leu Lys Lys Val Lys Gly Leu Gly Xaa
            100                 105                 110

Lys Ser Phe Gln Gln Cys Ala Gly Phe Ile Arg Ile Asn Gln Xaa Tyr
        115                 120                 125

Ile Arg Thr Phe Cys Ser Xaa Gln Thr Glu Thr Ser Gly Gln Ile Gln
    130                 135                 140

Gly Val Ala Val Thr Ser Ser Ala Asp Val Glu Val Thr Asn Glu Lys
145                 150                 155                 160

Gln Gly Lys Lys Lys Ser Lys Thr Ala Val Asn Val Leu Leu Lys Pro
                165                 170                 175

Asn Pro Leu Asp Gln Thr Cys Ile His Pro Glu Ser Tyr Asp Ile Ala
            180                 185                 190

Xaa Arg Phe Leu Ser Ser Ile Gly Gly Thr Leu Tyr Glu Val Gly Lys
        195                 200                 205

Pro Glu Met Gln Gln Lys Ile Asn Ser Phe Leu Glu Lys Xaa Gly Met
    210                 215                 220

Glu Lys Ile Ala Glu Arg Leu Gln Thr Thr Val His Thr Leu Gln Val
225                 230                 235                 240

His His Arg Trp Val Phe Ser Gln Pro Glu Gly Phe Asp Phe Arg Thr
                245                 250                 255

Asp Phe 




<210> 1482
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1482
Met Lys Gly Thr Thr Trp Leu Gln Lys Ser Pro Leu Ala Ser Ala Ser
  1               5                  10                  15

Pro Gly Val Ser Leu Ser Ala Gln Ala Gly Gln Arg Arg His His Asn
             20                  25                  30

His Arg His Pro Ser Asn His Ser Glu Arg Pro Phe Ala His Ala Trp
         35                  40                  45

Ser Leu Leu Arg Pro Gln Tyr Phe Xaa Leu Arg Pro Ala Arg Leu Ala
     50                  55                  60

Arg Arg Gly Ala Phe Ser Leu Ser Ala Tyr Phe Lys Thr Thr Xaa Phe
 65                  70                  75                  80

Cys Met Leu Gly Val Pro Val Cys Leu Leu Ala Ala Xaa Arg Gly Leu
                 85                  90                  95

Glu Met Lys Gln 
            100



<210> 1483
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1483
Met Ile Trp Leu Asp Cys Leu Phe Gly Val Ala Leu Lys Pro Glu Ser
  1               5                  10                  15

Ser Asp Leu Phe Phe Cys Val Ser Tyr Val Pro Gln Lys Trp Phe Phe
             20                  25                  30

Ile Leu Leu Pro Gly Ser Ala Val His Lys Met Ile Val Asp Arg Gln
         35                  40                  45

Tyr Met Gly Val Ser Lys Arg Lys Cys Ile Val Trp Gly Val Ala Phe
     50                  55                  60

Leu Ser Asp Gly Thr Ile Ile Ser Val Asp Ser Ala Gly Lys Val Gln
 65                  70                  75                  80

Phe Trp Asp Ser Ala Thr Gly Thr Leu Val Lys Ser His Leu Ile Ala
                 85                  90                  95

Asn Ala Asp Val Gln Ser Ile Ala Val Xaa Asp Gln Glu Asp Ser Phe
            100                 105                 110

Val Val Gly Thr Ala Glu Gly Thr Ser Leu Pro Phe Ser Xaa Gly Pro
        115                 120                 125

Cys Asp Ile 
    130



<210> 1484
<211> 142
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1484
Met Val Gly Met Arg Pro Ala Phe Ala Leu Ala Gln Pro Arg Leu Gln
  1               5                  10                  15

Pro His His Pro His Ser Arg Glu Arg Val Lys Ala Ala Pro Arg Asp
             20                  25                  30

Arg Ala Lys Thr Gln Ala Gln Thr Ala His Ser Ser Pro Gln Pro Leu
         35                  40                  45

Cys Pro Leu Val His Thr Val Phe Ile Leu Phe Pro Leu Ala Gly Pro
     50                  55                  60

Leu His Trp Glu Lys Met Lys Arg Leu Leu Arg Ser Ser Ser Lys Asp
 65                  70                  75                  80

Ser Gln Gly Lys Ser Cys Leu Xaa His Thr Gly Ser Cys Val Lys Thr
                 85                  90                  95

Trp Asp Gln Leu Ser Cys Cys Leu Gly Gln Lys Xaa Gly Cys Asp Trp
            100                 105                 110

Gln Val Pro Thr Gly Ala Ser Val Gly Xaa Gly Gly Trp Pro Arg Pro
        115                 120                 125

Gln Glu Arg Gln Thr Gly Leu Gly Arg Gly Xaa Arg Asn Pro 
    130                 135                 140



<210> 1485
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1485
Met Val Cys Ile Val Ile Gly Ala Arg Lys Leu Gly Val Asn Pro Asp
  1               5                  10                  15

Asn Ile Ala Thr Pro Ile Ala Ala Ser Leu Gly Asp Leu Ile Thr Leu
             20                  25                  30

Ser Ile Leu Ala Leu Val Ser Ser Phe Phe Tyr Arg His Lys Asp Ser
         35                  40                  45

Arg Tyr Leu Thr Pro Leu Val Cys Leu Ser Phe Ala Ala Leu Thr Pro
     50                  55                  60

Val Trp Val Leu Ile Ala Lys Gln Ser Pro Pro Ile Val Lys Ile Leu
 65                  70                  75                  80

Xaa Val Trp Leu Val Pro Asn His Pro Gly His Gly His Gln Gln Phe
                 85                  90                  95

Arg Arg Thr His Leu Glu Gln Asn Arg Phe 
            100                 105



<210> 1486
<211> 145
<212> PRT
<213> Homo sapiens

<400> 1486
Met Ser Thr Ser Ala Pro Pro Leu Ser Leu Ile Leu Gly Gly Cys Pro
  1               5                  10                  15

Ile Leu Phe Leu Gln Phe Tyr Trp Leu Leu Phe Cys Thr Asn Gln Ser
             20                  25                  30

Leu Ser Leu Phe Leu Ser Ser Pro Pro Leu Thr Leu Ala Leu Ser Ile
         35                  40                  45

Ser Leu Ser Arg Pro Pro Leu Leu Pro Leu Ala Pro Arg Leu Ile Ser
     50                  55                  60

Val His Ser Ile Leu Ser Pro Ser Leu Leu Pro Pro Ala Ala Pro Ser
 65                  70                  75                  80

Pro Ala His Phe Pro Glu Leu Cys Leu Pro Leu Leu Ile Cys Ser Ser
                 85                  90                  95

Ser Glu Ala Val Ser Leu Glu Val Val Gln Ser Trp Leu Gln Leu Ser
            100                 105                 110

Ala Ser Ala Phe Val Ser Cys Arg Leu Thr Arg Phe Phe Val Ile Ser
        115                 120                 125

Val Phe Leu Thr Arg Phe Lys Lys Lys Lys Arg Lys Lys Lys Lys Lys
    130                 135                 140

Lys 
145



<210> 1487
<211> 123
<212> PRT
<213> Homo sapiens

<400> 1487
Met Ile Pro Pro Leu Ser Pro Ala Pro Asn Gln Glu Leu Val Leu Gly
  1               5                  10                  15

Leu Cys Tyr Met Ser Tyr Leu Ala Phe Leu Tyr Met Thr Phe Asp Phe
             20                  25                  30

Cys Cys Leu Tyr Phe Ser Thr Val Tyr Ala Pro Ser Phe Lys Tyr Ile
         35                  40                  45

Cys Val His Thr Asp Thr His Ile Cys Val Cys Val Cys Ile Tyr Leu
     50                  55                  60

Ser Ser Val Val Ser Lys Ser Ser Ala Glu Ala Asp Gly Val Leu Gln
 65                  70                  75                  80

Pro Arg Arg His Pro Ala Ser Leu Leu Ile Val Phe Ala Thr Ser Ile
                 85                  90                  95

Ser Glu Ser Ser Leu Leu Ile Phe Ser Phe Gln Lys Thr Glu Ala Lys
            100                 105                 110

Leu Ile Val Phe Ala Val Ser Leu Ala Ala Lys 
        115                 120



<210> 1488
<211> 156
<212> PRT
<213> Homo sapiens

<400> 1488
Met Ser Leu Glu Phe Tyr Gln Lys Lys Lys Ser Arg Trp Pro Phe Ser
  1               5                  10                  15

Asp Glu Cys Ile Pro Trp Glu Val Trp Thr Val Lys Val His Val Val
             20                  25                  30

Ala Leu Ala Thr Glu Gln Glu Arg Gln Ile Cys Arg Glu Lys Val Gly
         35                  40                  45

Glu Lys Leu Cys Glu Lys Ile Ile Asn Ile Val Glu Val Met Asn Arg
     50                  55                  60

His Glu Tyr Leu Pro Lys Met Pro Thr Gln Ser Glu Val Asp Asn Val
 65                  70                  75                  80

Phe Asp Thr Gly Leu Arg Asp Val Gln Pro Tyr Leu Tyr Lys Ile Ser
                 85                  90                  95

Phe Gln Ile Thr Asp Ala Leu Gly Thr Ser Val Thr Thr Thr Met Arg
            100                 105                 110

Arg Leu Ile Lys Asp Thr Leu Pro Ser Glu Arg Arg Trp Ile Ser Gly
        115                 120                 125

Ser Ser Leu Met Ala Pro Arg Pro Trp Leu Leu Gly Ile Ala Leu Leu
    130                 135                 140

Gly Leu Trp Ala Leu Glu Pro Ala Leu Gly His Trp 
145                 150                 155



<210> 1489
<211> 240
<212> PRT
<213> Homo sapiens

<400> 1489
Met Gln Cys Phe Ser Phe Ile Lys Thr Met Met Ile Leu Phe Asn Leu
  1               5                  10                  15

Leu Ile Phe Leu Cys Gly Ala Ala Leu Leu Ala Val Gly Ile Trp Val
             20                  25                  30

Ser Ile Asp Gly Ala Ser Phe Leu Lys Ile Phe Gly Pro Leu Ser Ser
         35                  40                  45

Ser Ala Met Gln Phe Val Asn Val Gly Tyr Leu Ile Ala Ala Gly Val
     50                  55                  60

Val Val Phe Ala Leu Gly Phe Leu Gly Cys Tyr Gly Ala Lys Thr Glu
 65                  70                  75                  80

Ser Lys Cys Ala Leu Val Thr Phe Phe Phe Ile Leu Leu Leu Ile Phe
                 85                  90                  95

Ile Ala Glu Val Ala Ala Ala Val Val Ala Leu Val Tyr Thr Thr Met
            100                 105                 110

Ala Glu His Phe Leu Thr Leu Leu Val Val Pro Ala Ile Lys Lys Asp
        115                 120                 125

Tyr Gly Ser Gln Glu Asp Phe Thr Gln Val Trp Asn Thr Thr Met Lys
    130                 135                 140

Gly Leu Lys Cys Cys Gly Phe Thr Asn Tyr Thr Asp Phe Glu Asp Ser
145                 150                 155                 160

Pro Tyr Phe Lys Glu Asn Ser Ala Phe Pro Pro Phe Cys Cys Asn Asp
                165                 170                 175

Asn Val Thr Asn Thr Ala Asn Glu Thr Cys Thr Lys Gln Lys Ala His
            180                 185                 190

Asp Gln Lys Val Glu Gly Cys Phe Asn Gln Leu Leu Tyr Asp Ile Arg
        195                 200                 205

Thr Asn Ala Val Thr Val Gly Gly Val Ala Ala Gly Ile Gly Gly Leu
    210                 215                 220

Glu Leu Ala Ala Met Ile Val Ser Met Tyr Leu Tyr Cys Asn Leu Gln
225                 230                 235                 240






<210> 1490
<211> 246
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (239)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1490
Met Leu Ala Asp Lys His Ala Lys Glu Ile Glu Glu Glu Ser Glu Thr
  1               5                  10                  15

Thr Val Glu Ala Asp Leu Thr Asp Lys Gln Lys His Gln Leu Lys His
             20                  25                  30

Arg Glu Leu Phe Leu Ser Arg Gln Tyr Glu Ser Leu Pro Ala Thr His
         35                  40                  45

Ile Arg Gly Lys Cys Ser Val Ala Leu Leu Asn Glu Thr Glu Ser Val
     50                  55                  60

Leu Ser Tyr Leu Asp Lys Glu Asp Thr Phe Phe Tyr Ser Leu Val Tyr
 65                  70                  75                  80

Asp Pro Ser Leu Lys Thr Leu Leu Ala Asp Lys Gly Glu Ile Arg Val
                 85                  90                  95

Gly Pro Arg Tyr Gln Ala Asp Ile Pro Glu Met Leu Leu Glu Gly Glu
            100                 105                 110

Ser Asp Glu Arg Glu Gln Ser Lys Leu Glu Val Lys Val Trp Asp Pro
        115                 120                 125

Asn Ser Pro Leu Thr Asp Arg Gln Ile Asp Gln Phe Leu Val Val Ala
    130                 135                 140

Arg Ala Val Gly Thr Phe Ala Arg Ala Leu Asp Cys Ser Ser Ser Val
145                 150                 155                 160

Arg Gln Pro Ser Leu His Met Ser Ala Ala Ala Ala Ser Arg Asp Ile
                165                 170                 175

Thr Leu Phe His Ala Met Asp Thr Leu Tyr Arg His Ser Xaa Asp Leu
            180                 185                 190

Ser Ser Ala Ile Ser Val Leu Val Pro Leu Gly Gly Pro Val Leu Cys
        195                 200                 205

Arg Asp Glu Met Glu Glu Trp Ser Ala Ser Glu Ala Ser Leu Phe Glu
    210                 215                 220

Glu Ala Trp Lys Ile Gly Xaa Asp Phe Asn Asp Ile Xaa Gln Xaa Phe
225                 230                 235                 240

Phe Leu Gly Ile Ile Asp 
                245



<210> 1491
<211> 382
<212> PRT
<213> Homo sapiens

<400> 1491
Met Ala Val Gly Gln Ile Met Thr Phe Gly Ser Pro Val Ile Gly Cys
  1               5                  10                  15

Gly Phe Ile Ser Gly Trp Asn Leu Val Ser Met Cys Val Glu Tyr Val
             20                  25                  30

Leu Leu Trp Lys Val Tyr Gln Lys Thr Pro Ala Leu Ala Val Lys Ala
         35                  40                  45

Gly Leu Lys Glu Glu Glu Thr Glu Leu Lys Gln Leu Asn Leu His Lys
     50                  55                  60

Asp Thr Glu Pro Lys Pro Leu Glu Gly Thr His Leu Met Gly Val Lys
 65                  70                  75                  80

Asp Ser Asn Ile His Glu Leu Glu His Glu Gln Glu Pro Thr Cys Ala
                 85                  90                  95

Ser Gln Met Ala Glu Pro Phe Arg Thr Phe Arg Asp Gly Trp Val Ser
            100                 105                 110

Tyr Tyr Asn Gln Pro Val Phe Leu Ala Gly Met Gly Leu Ala Phe Leu
        115                 120                 125

Tyr Met Thr Val Leu Gly Phe Asp Cys Ile Thr Thr Gly Tyr Ala Tyr
    130                 135                 140

Thr Gln Gly Leu Ser Gly Phe His Pro Gln Tyr Phe Asp Gly Ser Ile
145                 150                 155                 160

Ser Tyr Asn Trp Asn Asn Gly Asn Cys Ser Phe Tyr Leu Ala Thr Ser
                165                 170                 175

Lys Met Trp Phe Gly Ser Ala Gly Leu Ile Ser Gly Leu Ala Gln Leu
            180                 185                 190

Ser Cys Leu Ile Leu Cys Val Ile Ser Val Phe Met Pro Gly Ser Pro
        195                 200                 205

Leu Asp Leu Ser Val Ser Pro Phe Glu Asp Ile Arg Ser Arg Phe Ile
    210                 215                 220

Gln Gly Glu Ser Ile Thr Pro Thr Lys Ile Pro Glu Ile Thr Thr Glu
225                 230                 235                 240

Ile Tyr Met Ser Asn Gly Ser Asn Ser Ala Asn Ile Val Pro Glu Thr
                245                 250                 255

Ser Pro Glu Ser Val Pro Ile Ile Ser Val Ser Leu Leu Phe Ala Gly
            260                 265                 270

Val Ile Ala Ala Arg Ile Gly Leu Trp Ser Phe Asp Leu Thr Val Thr
        275                 280                 285

Gln Leu Leu Gln Glu Asn Val Ile Glu Ser Glu Arg Gly Ile Ile Asn
    290                 295                 300

Gly Val Gln Asn Ser Met Asn Tyr Leu Leu Asp Leu Leu His Phe Ile
305                 310                 315                 320

Met Val Ile Leu Ala Pro Asn Pro Glu Ala Phe Gly Leu Leu Val Leu
                325                 330                 335

Ile Ser Val Ser Phe Val Ala Met Gly His Ile Met Tyr Phe Arg Phe
            340                 345                 350

Ala Gln Asn Thr Leu Gly Asn Lys Leu Phe Ala Cys Gly Pro Asp Ala
        355                 360                 365

Lys Glu Val Arg Lys Glu Asn Gln Ala Asn Thr Ser Val Val 
    370                 375                 380



<210> 1492
<211> 153
<212> PRT
<213> Homo sapiens

<400> 1492
Met Asn Val Gly Val Ala His Ser Glu Val Asn Pro Asn Thr Arg Val
  1               5                  10                  15

Met Asn Ser Arg Gly Ile Trp Leu Ala Tyr Ile Ile Leu Val Gly Leu
             20                  25                  30

Leu His Met Val Leu Leu Ser Ile Pro Phe Phe Ser Ile Pro Val Val
         35                  40                  45

Trp Thr Leu Thr Asn Val Ile His Asn Leu Ala Thr Tyr Val Phe Leu
     50                  55                  60

His Thr Val Lys Gly Thr Pro Phe Glu Thr Pro Asp Gln Gly Lys Ala
 65                  70                  75                  80

Arg Leu Leu Thr His Trp Glu Gln Met Asp Tyr Gly Leu Gln Phe Thr
                 85                  90                  95

Ser Ser Arg Lys Phe Leu Ser Ile Ser Pro Ile Val Leu Tyr Leu Leu
            100                 105                 110

Ala Ser Phe Tyr Thr Lys Tyr Asp Ala Ala His Phe Leu Ile Asn Thr
        115                 120                 125

Ala Ser Leu Leu Ser Val Leu Leu Pro Lys Leu Pro Gln Phe His Gly
    130                 135                 140

Val Arg Val Phe Gly Ile Asn Lys Tyr 
145                 150



<210> 1493
<211> 163
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1493
Met Gly Lys Gly Arg Phe Asp Glu Lys Glu Asn Val Ser Asn Cys Ile
  1               5                  10                  15

Gln Leu Lys Thr Ser Val Ile Lys Gly Ile Lys Asn Gln Leu Ile Glu
             20                  25                  30

Gln Phe Pro Gly Ile Glu Pro Trp Leu Asn Gln Ile Met Pro Lys Lys
         35                  40                  45

Asp Pro Val Lys Ile Val Arg Cys His Glu His Ile Xaa Ile Leu Thr
     50                  55                  60

Val Asn Gly Glu Leu Leu Phe Phe Arg Gln Arg Glu Gly Pro Phe Tyr
 65                  70                  75                  80

Pro Thr Leu Arg Leu Leu His Lys Tyr Pro Phe Ile Leu Pro His Gln
                 85                  90                  95

Gln Phe Asp Lys Gly Ser His Gln Ile Cys Thr Gln Leu Glu Gln Ile
            100                 105                 110

Ser Cys Phe Pro Gly Leu Leu Leu Leu Xaa Leu Asn Phe Thr Pro Ala
        115                 120                 125

Ala Val Asn Thr Ile Val Cys Tyr His Trp Pro Lys Arg Lys Thr Ala
    130                 135                 140

Cys Leu Phe Phe Gly Asn Pro Xaa Asn Phe Leu Gln Lys Xaa Leu Xaa
145                 150                 155                 160

Asn Phe Pro 




<210> 1494
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1494
Met Ala Gln Ile Val Leu Phe Ser Leu Phe Pro Val Ser Ile Asp Pro
  1               5                  10                  15

Val Arg Glu Gly Lys Leu Xaa Gln Ser Pro Ser Leu Gly Lys Ser Ser
             20                  25                  30

Trp Val Leu Ser Arg Xaa Leu Leu Ser Gly Trp Asp Tyr Arg His Glu
         35                  40                  45

Pro Pro Cys Pro Ala Asp Xaa Cys Leu Leu Lys Leu Gly Ile Phe Leu
     50                  55                  60

Pro Asn Leu Gly Phe Ser Gln Arg Pro Tyr Ile Ala Tyr Cys Cys Leu
 65                  70                  75                  80

Val Ser Ser Leu Leu Gln Asn Ser Tyr Leu Cys Ile Phe Phe Val Phe
                 85                  90                  95

Asn Asp Val Leu Lys Xaa Pro Gly 
            100



<210> 1495
<211> 109
<212> PRT
<213> Homo sapiens

<400> 1495
Met Pro Leu Cys Glu Arg Val Lys Met Asn Lys Arg Lys Arg Thr Gln
  1               5                  10                  15

Leu Met Lys Ser Gln Asn Met Leu Lys Ser Val Gln Met Lys Ile Met
             20                  25                  30

Ile Val Met Lys Leu Leu Asn Pro Leu Gly Asn Asp Ile Lys Lys Met
         35                  40                  45

Met Ile Lys Leu Gly Asn Met Lys Ser Val Thr Glu Glu Ala Leu Gly
     50                  55                  60

Ile Ile Gly Glu Val Ala Thr Leu Met Lys Glu Glu Gly Val Gln Val
 65                  70                  75                  80

Val Val Val Ile Glu Thr Glu Val Arg Gln Ile Leu Thr Trp Lys Ile
                 85                  90                  95

Ile Leu Leu Leu Pro Ala Leu Val Arg Leu Leu Gly Lys 
            100                 105



<210> 1496
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1496
Met Ala Asp Val Pro Gly Ala Gln Arg Ala Val Pro Gly Asp Gly Pro
  1               5                  10                  15

Glu Pro Arg Asp Pro Leu Asp Cys Trp Ala Cys Ala Val Leu Val Thr
             20                  25                  30

Ala Gln Asn Leu Leu Val Ala Ala Phe Asn Leu Leu Leu Leu Val Leu
         35                  40                  45

Val Leu Gly Thr Ile Leu Leu Pro Ala Val Thr Met Leu Gly Phe Gly
     50                  55                  60

Phe Leu Cys His Ser Gln Phe Leu Arg Ser Gln Gly Thr Pro Leu His
 65                  70                  75                  80

Arg Ala Pro Ala Glu Pro Arg Phe Ser Arg Ala Leu Leu Val Xaa Arg
                 85                  90                  95

Ile Ser Trp Phe Leu Arg Gly Arg Xaa Phe Val Val Xaa Phe Trp Ala
            100                 105                 110

Lys Leu Thr 
        115



<210> 1497
<211> 165
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1497
Met Leu Glu Asp Thr Gly Phe Trp Leu Glu Ser Lys Ile Leu Ser Phe
  1               5                  10                  15

Ile Gln Asp Gln Glu Glu Asp Tyr Leu Lys Leu His Arg Val Ile Tyr
             20                  25                  30

Gln Gln Ile Ile Gln Thr Tyr Leu Thr Val Cys Lys Asp Val Val Met
         35                  40                  45

Val Gly Leu Gly Asp His Gln Phe Gln Met Gln Leu Leu Gln Arg Ser
     50                  55                  60

Leu Gly Ile Met Gln Thr Val Lys Gly Phe Phe Tyr Val Ser Leu Leu
 65                  70                  75                  80

Leu Asp Ile Leu Lys Glu Ile Thr Gly Ser Ser Leu Ile Gln Lys Thr
                 85                  90                  95

Asp Ser Asp Glu Glu Val Ala Met Leu Leu Asp Thr Val Gln Xaa Val
            100                 105                 110

Phe Gln Lys Met Leu Glu Cys Ile Ala Arg Ser Phe Arg Lys Gln Pro
        115                 120                 125

Glu Glu Gly Leu Arg Cys Phe Ile Leu Phe Arg Gly Leu Phe Met Ser
    130                 135                 140

Ser Leu Leu Leu Phe Ser Leu Gly Thr Gln Thr Pro Leu Cys Thr Gly
145                 150                 155                 160

Val Tyr Phe Leu Leu 
                165



<210> 1498
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (37)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1498
Met Ala Glu Gly Glu Gly Tyr Phe Ala Met Ser Glu Asp Glu Leu Ala
  1               5                  10                  15

Cys Ser Pro Tyr Ile Pro Leu Gly Gly Asp Phe Gly Gly Gly Asp Phe
             20                  25                  30

Gly Gly Gly Asp Xaa Arg Arg Arg Arg Leu Arg Arg Arg Arg Leu Ser
         35                  40                  45

Ala Val Ala Ala Val Xaa Val Gly Ile Ala Trp Thr Ile Ala Lys Pro
     50                  55                  60

Tyr Gly Ala Leu Gln Cys Ala Glu Leu Gly Ala Ser Ala Ala Ala Gly
 65                  70                  75                  80

Arg His Pro Glu Arg Asp His Ser Asp Ser Arg Xaa Arg Gln Leu Pro
                 85                  90                  95

His Ala Arg Ala Ala Ala Glu Pro Asp Arg Glu Gly Gly Ala Ala Ala
            100                 105                 110

Pro Gly Arg Glu Ala His Xaa Arg Pro Arg Leu Arg Leu Asn Gly Ser
        115                 120                 125

Ala Ala Ser His Val Leu His Gln Asp Ser Gly Leu Gly Tyr Lys Asp
    130                 135                 140

Trp Thr Ser 
145



<210> 1499
<211> 100
<212> PRT
<213> Homo sapiens

<400> 1499
Met His Val Leu Phe Gln Leu Leu Tyr His Tyr Pro Lys Asp Gly Leu
  1               5                  10                  15

Leu Ile Gln Gln His Arg Phe Ile Leu Pro Val Phe Gln Leu Gln Ile
             20                  25                  30

Asn Glu Ile Ile Cys Thr Leu Val Ser Gly Phe Phe Asp Ser Thr Val
         35                  40                  45

Cys Leu Tyr Asn Ser Ser Val Leu Leu His Val Val Val Arg Ser Phe
     50                  55                  60

Ile Leu Leu Tyr Thr Val Leu Asn Cys Ile Asn Tyr Ser Phe Cys Tyr
 65                  70                  75                  80

Tyr Ala Phe Gly Leu Phe Pro Val Leu Ala Ile Met Asn Lys Ala Ala
                 85                  90                  95

Met Asn Ile Leu 
            100



<210> 1500
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1500
Met Asp Phe Gly Lys Cys Pro Arg Leu Arg Leu Phe Thr Gln Glu Tyr
  1               5                  10                  15

Ile Leu Ala Leu Asn Glu Leu Asn Ala Gly Met Glu Val Val Lys Lys
             20                  25                  30

Phe Ile Gln Ser Met His Gly Pro Thr Gly His Cys Pro His Pro Arg
         35                  40                  45

Val Leu Pro Asn Leu Val Ala Val Cys Leu Ala Ala Ile Tyr Ser Cys
     50                  55                  60

Tyr Glu Glu Phe Ile Asn Ser Arg Asp Asn Ser Pro Ser Leu Lys Glu
 65                  70                  75                  80

Ile Arg Asn Gly Cys Gln Gln Arg Ala Thr Gly Ser Pro Leu Tyr Leu
                 85                  90                  95

Cys Ala Phe Cys Thr Pro Ala Arg Thr Trp Cys Leu Arg Lys Pro Arg
            100                 105                 110

Cys Leu Arg Pro Gly Ser Ser Arg Trp Ser Trp Pro Pro Val Arg Ser
        115                 120                 125

Thr Trp Arg Trp Asn Ala Pro Xaa Leu Pro Ser Arg Arg 
    130                 135                 140



<210> 1501
<211> 276
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (260)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (273)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1501
Met Ser Arg Ser Val Leu Gln Pro Ser Gln Gln Lys Leu Ala Glu Lys
  1               5                  10                  15

Leu Thr Ile Leu Asn Asp Arg Gly Val Gly Met Leu Thr Arg Leu Tyr
             20                  25                  30

Asn Ile Lys Lys Ala Cys Gly Asp Pro Lys Ala Lys Pro Ser Tyr Leu
         35                  40                  45

Ile Asp Lys Asn Leu Glu Ser Ala Val Lys Phe Ile Val Arg Lys Phe
     50                  55                  60

Pro Ala Val Glu Thr Arg Asn Asn Asn Gln Gln Leu Ala Gln Leu Gln
 65                  70                  75                  80

Lys Glu Lys Ser Glu Ile Leu Lys Asn Leu Ala Leu Tyr Tyr Phe Thr
                 85                  90                  95

Phe Val Asp Val Met Glu Phe Lys Asp His Val Cys Glu Leu Leu Asn
            100                 105                 110

Thr Ile Asp Val Cys Gln Val Phe Phe Asp Ile Thr Val Asn Phe Asp
        115                 120                 125

Leu Thr Lys Asn Tyr Leu Asp Leu Ile Ile Thr Tyr Thr Thr Leu Met
    130                 135                 140

Ile Leu Leu Ser Arg Ile Glu Glu Arg Lys Ala Ile Ile Gly Leu Tyr
145                 150                 155                 160

Asn Tyr Ala His Glu Met Thr His Gly Ala Ser Asp Arg Glu Tyr Pro
                165                 170                 175

Arg Leu Gly Gln Met Ile Val Asp Tyr Glu Asn Pro Leu Lys Lys Met
            180                 185                 190

Met Glu Glu Phe Val Pro His Ser Lys Ser Leu Ser Asp Ala Leu Ile
        195                 200                 205

Ser Leu Gln Met Val Tyr Pro Arg Arg Asn Leu Ser Ala Asp Gln Trp
    210                 215                 220

Arg Asn Ala Gln Leu Leu Ser Leu Ile Ser Ala Pro Ser Thr Met Leu
225                 230                 235                 240

Asn Pro Ala Gln Ser Asp Thr Met Pro Cys Glu Tyr Leu Ser Leu Gly
                245                 250                 255

Cys Asn Gly Xaa Ile Gly Leu Ser Leu Ala Leu Phe Val Pro Trp Gly
            260                 265                 270

Xaa Leu Asn Thr 
        275



<210> 1502
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1502
Met His Pro Asp Asn Ser Lys Ala Pro Gly Phe Arg Pro Pro Ser Gln
  1               5                  10                  15

Arg Val Ser Thr Ser Pro Val Gly Leu Pro Ser Ile Asp Pro Ser Gly
             20                  25                  30

Ser Ser Pro Ser Ser Ser Ser Ala Pro Leu Ala Ser Phe Ser Gly Ile
         35                  40                  45

Pro Gly Thr Arg Val Phe Leu Gln Gly Gln Leu Leu Leu Gly Leu Leu
     50                  55                  60

Val Ser Thr Asp Asn Ile Phe Leu Pro Ile Leu Gly Gln Ala Pro Gln
 65                  70                  75                  80

Thr His Pro Leu Leu Pro His Gln Arg Trp Ala Asn Gln Lys Glu Ser
                 85                  90                  95

Val Pro Val Lys Ile Glu Arg Tyr Leu Pro Gln Leu Glu Gln Arg Asp
            100                 105                 110

Trp Pro Glu Phe Gly Lys Glu Gly Leu Leu His Lys Pro Arg Arg Gly
        115                 120                 125

Thr Ser Phe Val Ala Pro Val Gly Thr Gln Trp Glu Ser Gly Ser Phe
    130                 135                 140

Gly Val Gln Cys Cys Val Xaa Gly Xaa Ile Gly Trp Gly Xaa Leu Trp
145                 150                 155                 160

Xaa Gly Glu Pro Ser Asn Gly 
                165



<210> 1503
<211> 114
<212> PRT
<213> Homo sapiens

<400> 1503
Met Gln Met Tyr Ser Arg Gln Leu Ala Ser Thr Glu Trp Leu Thr Ile
  1               5                  10                  15

Gln Gly Gly Leu Leu Gly Ser Gly Leu Phe Val Phe Ser Leu Thr Ala
             20                  25                  30

Phe Asn Asn Leu Glu Asn Leu Val Phe Gly Lys Gly Phe Gln Ala Lys
         35                  40                  45

Ile Phe Pro Glu Ile Leu Leu Cys Leu Leu Leu Ala Leu Phe Ala Ser
     50                  55                  60

Gly Leu Ile His Arg Val Cys Val Thr Thr Cys Phe Ile Phe Ser Met
 65                  70                  75                  80

Val Gly Leu Tyr Tyr Ile Asn Lys Ile Ser Ser Thr Leu Tyr Gln Ala
                 85                  90                  95

Ala Ala Pro Val Leu Thr Pro Ala Lys Val Thr Gly Lys Ser Lys Lys
            100                 105                 110

Arg Asn 




<210> 1504
<211> 270
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1504
Met Gln Phe Leu Glu Asn Tyr Glu Lys Glu Asp Ile Thr Val Ala Glu
  1               5                  10                  15

Leu Glu Gly Asn Ser Asn Ser Leu Trp Thr Ile Ser Pro Pro Ser Lys
             20                  25                  30

Gln Lys Met Ile His Glu Leu Leu Asp Pro Asn Ser Ser Phe Ser Val
         35                  40                  45

Val Phe Ser Trp Ser Ile Gln Arg Asn Leu Ser Leu Gly Ala Lys Ser
     50                  55                  60

Glu Ile Ala Thr Asp Lys Leu Ser Phe Pro Leu Lys Asn Ile Thr Arg
 65                  70                  75                  80

Lys Asn Ile Ala Lys Met Ile Ala Gly Asn Ser Thr Glu Ser Ser Lys
                 85                  90                  95

Thr Pro Val Thr Ile Xaa Lys Xaa Tyr Pro Tyr Tyr Val Lys Ala Pro
            100                 105                 110

Ser Xaa Ser Asn Ser Lys Pro Ile Lys Gln Leu Leu Ser Glu Asn Asn
        115                 120                 125

Phe Met Xaa Ile Thr Ile Ile Leu Ser Arg Asp Asn Thr Thr Lys Tyr
    130                 135                 140

Asn Ser Glu Trp Trp Val Leu Asn Leu Thr Gly Asn Arg Ile Tyr Asn
145                 150                 155                 160

Pro Asn Ser Gln Ala Leu Glu Leu Val Val Phe Asn Asp Lys Val Ser
                165                 170                 175

Pro Pro Ser Leu Gly Phe Leu Ala Gly Tyr Gly Ile Met Gly Leu Tyr
            180                 185                 190

Ala Ser Val Val Leu Val Ile Gly Lys Phe Val Arg Glu Phe Phe Ser
        195                 200                 205

Gly Ile Ser His Ser Ile Met Phe Glu Glu Leu Pro Asn Val Asp Arg
    210                 215                 220

Ile Leu Lys Leu Cys Thr Asp Ile Phe Leu Val Arg Glu Thr Gly Glu
225                 230                 235                 240

Leu Glu Leu Glu Glu Asp Leu Tyr Ala Lys Leu Ile Phe Leu Tyr Arg
                245                 250                 255

Ser Pro Glu Thr Met Ile Lys Trp Thr Arg Glu Lys Thr Asn 
            260                 265                 270



<210> 1505
<211> 132
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1505
Met Ser Ser Val Glu Glu Asp Asp Tyr Asp Thr Leu Thr Asp Ile Asp
  1               5                  10                  15

Ser Asp Lys Asn Val Ile Arg Thr Lys Gln Tyr Leu Tyr Val Ala Asp
             20                  25                  30

Leu Ala Arg Lys Asp Lys Arg Val Leu Arg Lys Lys Tyr Gln Ile Tyr
         35                  40                  45

Phe Trp Asn Ile Ala Thr Ile Ala Val Phe Tyr Ala Leu Pro Val Val
     50                  55                  60

Gln Leu Val Ile Thr Tyr Gln Thr Val Val Asn Val Thr Gly Asn Gln
 65                  70                  75                  80

Asp Ile Cys Tyr Tyr Asn Phe Leu Xaa Ala His Pro Leu Gly Gln Ser
                 85                  90                  95

Gln Arg Leu Thr Thr Thr Ser Ser Ala Thr Trp Gly Thr Ser Cys Trp
            100                 105                 110

Gly Cys Phe Ser Ala His Gln Pro Cys Xaa Gly Glu Ile Asn Gln Lys
        115                 120                 125

Pro Gly Xaa Trp 
    130



<210> 1506
<211> 108
<212> PRT
<213> Homo sapiens

<400> 1506
Met Gly Phe Thr Gly Met Leu Gln Ser Arg Thr Val Val Phe Tyr Val
  1               5                  10                  15

Pro Cys Met Val Ile Leu Val Ala Ile Cys Cys Lys Ile Leu Glu Ala
             20                  25                  30

Lys Cys Leu Gln Tyr Arg Phe Leu Ala Thr Val Tyr Ala Val Ile Ser
         35                  40                  45

Leu Cys Leu Ser Trp Ala Val Leu Glu Asn Thr Leu Val Phe Thr Ile
     50                  55                  60

Trp Phe Thr Asn Thr Ile Ile Ile Leu Pro Gly Leu Lys Cys Arg Ile
 65                  70                  75                  80

Trp His Ile Asp Ala Cys Asn Gly Lys Lys Lys Asn Leu Leu Lys Phe
                 85                  90                  95

Val Asn Val Gln Leu Asn Leu Arg Tyr Thr Val Gly 
            100                 105



<210> 1507
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1507
Met Thr His Ser Gly Leu Trp Arg Thr Cys Cys Leu Glu Gly Ala Phe
  1               5                  10                  15

Arg Gly Val Cys Lys Lys Ile Asp His Phe Pro Glu Asp Ala Asp Tyr
             20                  25                  30

Glu Gln Asp Thr Ala Glu Tyr Leu Leu Arg Ala Val Arg Ala Ser Ser
         35                  40                  45

Val Phe Pro Ile Leu Ser Val Thr Leu Leu Phe Phe Gly Gly Leu Cys
     50                  55                  60

Val Ala Ala Ser Glu Phe His Arg Ser Arg His Asn Val Ile Leu Ser
 65                  70                  75                  80

Ala Gly Ile Phe Phe Val Ser Ala Gly Leu Ser Asn Ile Ile Gly Ile
                 85                  90                  95

Ile Val Tyr Ile Ser Ala Asn Ala Gly Asp Pro Gly Ala Ala Trp Xaa
            100                 105                 110

Pro Lys Lys Val Xaa Pro Met Val Gly Pro Phe Ile Phe Gly Ser Leu
        115                 120                 125

Leu Phe His His Arg Gln Glu Ile Cys 
    130                 135



<210> 1508
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1508
Met Ala Arg Glu Ala Val Tyr Thr Met Gly Leu Asn Gly Gly Gln Leu
  1               5                  10                  15

Gly Cys Leu Leu Asp Pro Asn Gly Glu Lys Cys Val Thr Ala Pro Arg
             20                  25                  30

Gln Val Ser Ala Leu His His Lys Asp Ile Ala Leu Ser Leu Val Ala
         35                  40                  45

Ala Ser Asp Gly Ala Thr Val Cys Val Thr Thr Arg Gly Asp Ile Tyr
     50                  55                  60

Leu Leu Ala Asp Tyr Gln Cys Lys Lys Met Ala Ser Lys Gln Leu Asn
 65                  70                  75                  80

Leu Lys Lys Val Leu Val Ser Gly Gly His Met Glu Tyr Lys Val Asp
                 85                  90                  95

Pro Glu His Leu Lys Glu Asn Gly Gly Gln Lys Ile Cys Ile Leu Ala
            100                 105                 110

Met Asp Gly Ala Gly Arg Val Phe Cys Trp Arg Xaa Val Asn Ser Ser
        115                 120                 125

Leu Lys Gln Cys Arg Trp Ala Tyr His Val Arg Ser Ser Phe Leu Ile
    130                 135                 140






<210> 1509
<211> 110
<212> PRT
<213> Homo sapiens

<400> 1509
Met Phe His Leu Ile Thr Thr Lys Tyr Leu Glu Asp Leu Ser Tyr Ser
  1               5                  10                  15

Asp Ser Thr Arg Cys Thr Glu Ala Ala Asp Lys Ile Phe Gln Ile Ser
             20                  25                  30

Arg Glu Thr Pro Glu Pro Leu Leu Leu Leu His Trp His Ala Asp Glu
         35                  40                  45

Ile Val Thr Cys Pro His Trp Leu Leu Pro His Leu Val Ala Leu Val
     50                  55                  60

Met Met Gly Ser Leu His Leu Pro Gln Ser Gln Ile Leu Glu Pro Ser
 65                  70                  75                  80

Val Pro Ala Glu Ala Val Tyr Val Ser Trp Leu Pro Lys Asp Thr Pro
                 85                  90                  95

Ala Glu Pro Phe Leu Gly Lys Glu His Leu Gln Arg Arg His 
            100                 105                 110



<210> 1510
<211> 148
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (147)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1510
Met Ser Ile Thr Thr Gly Gln Lys Leu Leu Lys Ser Arg Ile Leu Phe
  1               5                  10                  15

His Pro Arg Ser Leu Arg Gly Leu Gln Met Ile Leu Asn Ser Asp Arg
             20                  25                  30

Tyr Ala Pro Ser Leu His Glu Leu Gly His Phe Asn Ile Pro Thr Leu
         35                  40                  45

Cys Asp Pro Ala Asn Leu Gln Trp Phe Ile Leu Thr Lys Ala Gln Gln
     50                  55                  60

Ala Arg Glu Asn Met Lys Arg Lys Glu Glu Leu Lys Val Ile Glu Asn
 65                  70                  75                  80

Glu Leu Ile Gln Ala Ser Thr Lys Lys Phe Ser Leu Glu Lys Leu Tyr
                 85                  90                  95

Lys Glu Pro Ser Ile Leu Val Tyr Lys Trp Trp Ile Val Val Arg Ala
            100                 105                 110

Leu Glu Gln His Cys Leu Pro Thr Trp Asp Ala Leu Cys Ile Tyr Ile
        115                 120                 125

Phe Leu Cys Tyr Ala Arg Trp Arg Leu Cys Ile Leu Gly Ile Gly Arg
    130                 135                 140

Met Glu Xaa His 
145



<210> 1511
<211> 198
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (188)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1511
Met Phe Ala Val His Ser Val Asn Leu Leu Leu Lys Ser Ile Gly Ala
  1               5                  10                  15

Thr Leu Thr Asp Val Asp Asp Leu Ile Phe Lys Leu Ala Tyr Tyr Glu
             20                  25                  30

Ile Arg Tyr Gln Phe Tyr Lys Arg Asp Gln Leu Ile Trp Ser Val Val
         35                  40                  45

Arg His Tyr Ser Glu Gln Phe Leu Lys Gln Met Tyr Val Leu Val Leu
     50                  55                  60

Gly Leu Asp Val Leu Gly Asn Pro Phe Gly Leu Ile Arg Gly Leu Ser
 65                  70                  75                  80

Glu Gly Val Glu Ala Leu Phe Tyr Glu Pro Phe Gln Gly Ala Val Gln
                 85                  90                  95

Gly Pro Glu Glu Phe Ala Glu Gly Leu Val Ile Gly Val Arg Ser Leu
            100                 105                 110

Phe Gly His Thr Val Gly Gly Ala Ala Gly Val Val Ser Arg Ile Thr
        115                 120                 125

Gly Ser Val Gly Lys Gly Leu Ala Ala Ile Thr Met Asp Lys Glu Tyr
    130                 135                 140

Gln Gln Lys Arg Arg Glu Glu Leu Ser Arg Gln Pro Arg Asp Phe Gly
145                 150                 155                 160

Asp Ser Leu Ala Arg Gly Gly Lys Gly Phe Leu Arg Gly Val Val Gly
                165                 170                 175

Gly Val Thr Gly Ile Ile Thr Lys Pro Val Gly Xaa Cys Gln Lys Gly
            180                 185                 190

Arg Ser Cys Trp Ile Leu 
        195



<210> 1512
<211> 545
<212> PRT
<213> Homo sapiens

<400> 1512
Met Ala Gly Ala Ile Ile Glu Asn Met Ser Thr Lys Lys Leu Cys Ile
  1               5                  10                  15

Val Gly Gly Ile Leu Leu Val Phe Gln Ile Ile Ala Phe Leu Val Gly
             20                  25                  30

Gly Leu Ile Ala Pro Gly Pro Thr Thr Ala Val Ser Tyr Met Ser Val
         35                  40                  45

Lys Cys Val Asp Ala Arg Lys Asn His His Lys Thr Lys Trp Phe Val
     50                  55                  60

Pro Trp Gly Pro Asn His Cys Asp Lys Ile Arg Asp Ile Glu Glu Ala
 65                  70                  75                  80

Ile Pro Arg Glu Ile Glu Ala Asn Asp Ile Val Phe Ser Val His Ile
                 85                  90                  95

Pro Leu Pro His Met Glu Met Ser Pro Trp Phe Gln Phe Met Leu Phe
            100                 105                 110

Ile Leu Gln Leu Asp Ile Ala Phe Lys Leu Asn Asn Gln Ile Arg Glu
        115                 120                 125

Asn Ala Glu Val Ser Met Asp Val Ser Leu Ala Tyr Arg Asp Asp Ala
    130                 135                 140

Phe Ala Glu Trp Thr Glu Met Ala His Glu Arg Val Pro Arg Lys Leu
145                 150                 155                 160

Lys Cys Thr Phe Thr Ser Pro Lys Thr Pro Glu His Glu Gly Arg Tyr
                165                 170                 175

Tyr Glu Cys Asp Val Leu Pro Phe Met Glu Ile Gly Ser Val Ala His
            180                 185                 190

Lys Phe Tyr Leu Leu Asn Ile Arg Leu Pro Val Asn Glu Lys Lys Lys
        195                 200                 205

Ile Asn Val Gly Ile Gly Glu Ile Lys Asp Ile Arg Leu Val Gly Ile
    210                 215                 220

His Gln Asn Gly Gly Phe Thr Lys Val Trp Phe Ala Met Lys Thr Phe
225                 230                 235                 240

Leu Thr Pro Ser Ile Phe Ile Ile Met Val Trp Tyr Trp Arg Arg Ile
                245                 250                 255

Thr Met Met Ser Arg Pro Pro Val Leu Leu Glu Lys Val Ile Phe Ala
            260                 265                 270

Leu Gly Ile Ser Met Thr Phe Ile Asn Ile Pro Val Glu Trp Phe Ser
        275                 280                 285

Ile Gly Phe Asp Trp Thr Trp Met Leu Leu Phe Gly Asp Ile Arg Gln
    290                 295                 300

Gly Ile Phe Tyr Ala Met Leu Leu Ser Phe Trp Ile Ile Phe Cys Gly
305                 310                 315                 320

Glu His Met Met Asp Gln His Glu Arg Asn His Ile Ala Gly Tyr Trp
                325                 330                 335

Lys Gln Val Gly Pro Ile Ala Val Gly Ser Phe Cys Leu Phe Ile Phe
            340                 345                 350

Asp Met Cys Glu Arg Gly Val Gln Leu Thr Asn Pro Phe Tyr Ser Ile
        355                 360                 365

Trp Thr Thr Asp Ile Gly Thr Glu Leu Ala Met Ala Phe Ile Ile Val
    370                 375                 380

Ala Gly Ile Cys Leu Cys Leu Tyr Phe Leu Phe Leu Cys Phe Met Val
385                 390                 395                 400

Phe Gln Val Phe Arg Asn Ile Ser Gly Lys Gln Ser Ser Leu Pro Ala
                405                 410                 415

Met Ser Lys Val Arg Arg Leu His Tyr Glu Gly Leu Ile Phe Arg Phe
            420                 425                 430

Lys Phe Leu Met Leu Ile Thr Leu Ala Cys Ala Ala Met Thr Val Ile
        435                 440                 445

Phe Phe Ile Val Ser Gln Val Thr Glu Gly His Trp Lys Trp Gly Gly
    450                 455                 460

Val Thr Val Gln Val Asn Ser Ala Phe Phe Thr Gly Ile Tyr Gly Met
465                 470                 475                 480

Trp Asn Leu Tyr Val Phe Ala Leu Met Phe Leu Tyr Ala Pro Ser His
                485                 490                 495

Lys Asn Tyr Gly Glu Asp Gln Ser Asn Gly Met Gln Leu Pro Cys Lys
            500                 505                 510

Ser Arg Glu Asp Cys Ala Leu Phe Val Ser Glu Leu Tyr Gln Glu Leu
        515                 520                 525

Phe Ser Ala Ser Lys Tyr Ser Phe Ile Asn Asp Asn Ala Ala Ser Gly
    530                 535                 540

Ile 
545



<210> 1513
<211> 203
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (192)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (196)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1513
Met Tyr Xaa Leu Lys Pro Glu Cys Ala Lys Gln Phe Asn Leu Tyr Phe
  1               5                  10                  15

Tyr His Phe Ser Arg Ala Glu Gln Ser Lys Ala Glu Glu Ala Gln Arg
             20                  25                  30

Lys Leu Lys Arg Gln Asn Arg Glu Asp Thr Ala Leu Pro Pro Pro Val
         35                  40                  45

Leu Pro Pro Phe Cys Pro Leu Phe Ala Ser Leu Val Asn Ile Leu Gln
     50                  55                  60

Ser Asp Val Met Leu Cys Ile Met Gly Thr Ile Leu Gln Trp Ala Val
 65                  70                  75                  80

Glu His Asn Gly Tyr Ala Trp Ser Glu Ser Met Leu Gln Arg Val Leu
                 85                  90                  95

His Leu Ile Gly Met Ala Leu Gln Glu Glu Lys Gln His Leu Glu Asn
            100                 105                 110

Val Thr Glu Glu His Val Val Thr Phe Thr Phe Thr Gln Lys Ile Ser
        115                 120                 125

Lys Pro Gly Glu Ala Pro Lys Asn Ser Pro Ser Ile Leu Ala Met Leu
    130                 135                 140

Glu Thr Leu Gln Asn Ala Pro Tyr Leu Glu Val His Lys Asp Met Ile
145                 150                 155                 160

Arg Trp Ile Leu Lys Thr Phe Asn Ala Val Lys Lys Met Lys Glu Ser
                165                 170                 175

Ser Pro Thr Ser Pro Val Ala Glu Thr Glu Gly Thr Ile Met Glu Xaa
            180                 185                 190

His Asn Ser Xaa Phe Lys Gly Gln Arg Gln Ala 
        195                 200



<210> 1514
<211> 130
<212> PRT
<213> Homo sapiens

<400> 1514
Met Thr Ser Asn Leu Lys Trp Ser Ser Ala Thr Met Lys Ile Asp Asn
  1               5                  10                  15

Pro His Ile Thr Tyr Thr Ala Arg Val Pro Val Asp Val His Glu Tyr
             20                  25                  30

Asn Leu Thr His Leu Gln Pro Ser Thr Asp Tyr Glu Val Cys Leu Thr
         35                  40                  45

Val Ser Asn Ile His Gln Gln Thr Gln Lys Ser Cys Val Asn Val Thr
     50                  55                  60

Thr Lys Asn Ala Ala Phe Ala Val Asp Ile Ser Asp Gln Glu Thr Ser
 65                  70                  75                  80

Thr Ala Leu Ala Ala Val Met Gly Ser Met Phe Ala Val Ile Ser Leu
                 85                  90                  95

Ala Ser Ile Ala Val Tyr Phe Ala Lys Arg Phe Lys Arg Lys Asn Tyr
            100                 105                 110

His His Phe Ile Lys Lys Val Leu Trp Gln Lys Thr Ser Phe Asn Pro
        115                 120                 125

Thr Lys 
    130



<210> 1515
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1515
Met Ala Met Phe Phe Ser Ser Ser Leu His Glu Ile Pro Ser Pro Ser
  1               5                  10                  15

Pro Pro Glu Lys Lys Lys Arg Ile Ile Pro Leu Leu Glu Cys Ser Leu
             20                  25                  30

Glu Ile Ile Asn Ser Lys Leu Cys Thr Ser Leu Lys Phe Ile Phe Thr
         35                  40                  45

Gly Thr Leu Glu Leu Ser Leu Gln Leu Leu His Ala Ile Pro Leu Val
     50                  55                  60

Tyr Leu Ser Ser Val Gly Phe Thr Val Cys Leu Pro Pro Gln Thr Asn
 65                  70                  75                  80

Leu Leu His Gln Met Phe Ser Leu Thr Cys Leu Xaa Gly Cys His Phe
                 85                  90                  95

Phe Xaa Ile Phe Phe Xaa His Phe Tyr His 
            100                 105



<210> 1516
<211> 492
<212> PRT
<213> Homo sapiens

<400> 1516
Met Lys Ala Phe His Thr Phe Cys Val Val Leu Leu Val Phe Gly Ser
  1               5                  10                  15

Val Ser Glu Ala Lys Phe Asp Asp Phe Glu Asp Glu Glu Asp Ile Val
             20                  25                  30

Glu Tyr Asp Asp Asn Asp Phe Ala Glu Phe Glu Asp Val Met Glu Asp
         35                  40                  45

Ser Val Thr Glu Ser Pro Gln Arg Val Ile Ile Thr Glu Asp Asp Glu
     50                  55                  60

Asp Glu Thr Thr Val Glu Leu Glu Gly Gln Asp Glu Asn Gln Glu Gly
 65                  70                  75                  80

Asp Phe Glu Asp Ala Asp Thr Gln Glu Gly Asp Thr Glu Ser Glu Pro
                 85                  90                  95

Tyr Asp Asp Glu Glu Phe Glu Gly Tyr Glu Asp Lys Pro Asp Thr Ser
            100                 105                 110

Ser Ser Lys Asn Lys Asp Pro Ile Thr Ile Val Asp Val Pro Ala His
        115                 120                 125

Leu Gln Asn Ser Trp Glu Ser Tyr Tyr Leu Glu Ile Leu Met Val Thr
    130                 135                 140

Gly Leu Leu Ala Tyr Ile Met Asn Tyr Ile Ile Gly Lys Asn Lys Asn
145                 150                 155                 160

Ser Arg Leu Ala Gln Ala Trp Phe Asn Thr His Arg Glu Leu Leu Glu
                165                 170                 175

Ser Asn Phe Thr Leu Val Gly Asp Asp Gly Thr Asn Lys Glu Ala Thr
            180                 185                 190

Ser Thr Gly Lys Leu Asn Gln Glu Asn Glu His Ile Tyr Asn Leu Trp
        195                 200                 205

Cys Ser Gly Arg Val Cys Cys Glu Gly Met Leu Ile Gln Leu Arg Phe
    210                 215                 220

Leu Lys Arg Gln Asp Leu Leu Asn Val Leu Ala Arg Met Met Arg Pro
225                 230                 235                 240

Val Ser Asp Gln Val Gln Ile Lys Val Thr Met Asn Asp Glu Asp Met
                245                 250                 255

Asp Thr Tyr Val Phe Ala Val Gly Thr Arg Lys Ala Leu Val Arg Leu
            260                 265                 270

Gln Lys Glu Met Gln Asp Leu Ser Glu Phe Cys Ser Asp Lys Pro Lys
        275                 280                 285

Ser Gly Ala Lys Tyr Gly Leu Pro Asp Ser Leu Ala Ile Leu Ser Glu
    290                 295                 300

Met Gly Glu Val Thr Asp Gly Met Met Asp Thr Lys Met Val His Phe
305                 310                 315                 320

Leu Thr His Tyr Ala Asp Lys Ile Glu Ser Val His Phe Ser Asp Gln
                325                 330                 335

Phe Ser Gly Pro Lys Ile Met Gln Glu Glu Gly Gln Pro Leu Lys Leu
            340                 345                 350

Pro Asp Thr Lys Arg Thr Leu Leu Phe Thr Phe Asn Val Pro Gly Ser
        355                 360                 365

Gly Asn Thr Tyr Pro Lys Asp Met Glu Ala Leu Leu Pro Leu Met Asn
    370                 375                 380

Met Val Ile Tyr Ser Ile Asp Lys Ala Lys Lys Phe Arg Leu Asn Arg
385                 390                 395                 400

Glu Gly Lys Gln Lys Ala Asp Lys Asn Arg Ala Arg Val Glu Glu Asn
                405                 410                 415

Phe Leu Lys Leu Thr His Val Gln Arg Gln Glu Ala Ala Gln Ser Arg
            420                 425                 430

Arg Glu Glu Lys Lys Arg Ala Glu Lys Glu Arg Ile Met Asn Glu Glu
        435                 440                 445

Asp Pro Glu Lys Gln Arg Arg Leu Glu Glu Ala Ala Leu Arg Arg Glu
    450                 455                 460

Gln Lys Lys Leu Glu Lys Lys Gln Met Lys Met Lys Gln Ile Lys Val
465                 470                 475                 480

Lys Ala His Val Lys Pro Ser Gln Arg Phe Glu Phe 
                485                 490



<210> 1517
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1517
Met Lys Gly Glu Ile Gln Gln Ser Leu Gly Ala Trp Val Leu Leu Thr
  1               5                  10                  15

Val Asp Ile Gln Pro Xaa Cys Leu Gly Leu Tyr Cys Gly Lys Thr Leu
             20                  25                  30

Leu Phe Lys Asn Gly Ser Thr Glu Ile Tyr Gly Glu Cys Gly Val Cys
         35                  40                  45

Pro Arg Gly Gln Arg Thr Asn Ala Gln Lys Tyr Cys Gln Pro Cys Thr
     50                  55                  60

Glu Ser Pro Glu Leu Tyr Asp Trp Xaa Xaa Leu Gly Phe Met Ala Met
 65                  70                  75                  80

Leu Pro Leu Val Leu His Trp Phe Phe Ile Glu Trp Tyr Ser Gly Lys
                 85                  90                  95

Lys Ser Ser Ser Ala Leu Phe Gln His Ile Thr Ala Leu Phe Glu Cys
            100                 105                 110

Arg His Gly Ser Tyr Tyr His Leu Thr Cys Glu 
        115                 120



<210> 1518
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1518
Met Phe Xaa Met Arg Ala Glu Glu Thr Val Gln Arg Leu Pro Xaa Leu
  1               5                  10                  15

Gly His Cys Ala Thr Leu Ile Pro Pro Glu Leu Asp Pro Trp Thr Phe
             20                  25                  30

Ala Leu Thr Leu Ser Arg Pro Lys Ser Cys Leu Leu Val Ala Val Phe
         35                  40                  45

Pro Gln Arg Gly Ser Trp Asp His Ala Ser His Phe Leu Pro Gln Ala
     50                  55                  60

Pro Cys Gln Xaa Leu Asp Ala Pro Tyr Ser Ser Gly Asp Cys Pro Gly
 65                  70                  75                  80

Arg Pro Val Val Val Arg Glu Ser Val Ser Val Leu Leu Leu Ser Leu
                 85                  90                  95

Leu Gly Pro Leu Cys Leu Arg Met Leu Asn Asp Ser Ser Leu Ser Leu
            100                 105                 110

Cys Leu Met His 
        115



<210> 1519
<211> 162
<212> PRT
<213> Homo sapiens

<400> 1519
Met Arg Ile Ala Asn Arg Thr Arg Phe Ser Ser Pro Phe Leu Ala Arg
  1               5                  10                  15

Gly Ala Gly Trp Thr His Gly Arg Gly Met Met Val Val Gly Thr Gly
             20                  25                  30

Thr Ser Leu Ala Leu Ser Ser Leu Leu Ser Leu Leu Leu Phe Ala Gly
         35                  40                  45

Met Gln Met Tyr Ser Arg Gln Leu Ala Ser Thr Glu Trp Leu Thr Ile
     50                  55                  60

Gln Gly Gly Leu Leu Gly Ser Gly Leu Phe Val Phe Ser Leu Thr Ala
 65                  70                  75                  80

Phe Asn Asn Leu Glu Asn Leu Val Phe Gly Lys Gly Phe Gln Ala Lys
                 85                  90                  95

Ile Phe Pro Glu Ile Leu Leu Cys Leu Leu Leu Ala Leu Phe Ala Ser
            100                 105                 110

Gly Leu Ile His Arg Val Cys Val Thr Thr Cys Phe Ile Phe Ser Met
        115                 120                 125

Val Gly Leu Tyr Tyr Ile Asn Lys Ile Ser Ser Thr Leu Tyr Gln Ala
    130                 135                 140

Ala Ala Pro Val Leu Thr Pro Ala Lys Val Thr Gly Lys Ser Lys Lys
145                 150                 155                 160

Arg Asn 




<210> 1520
<211> 416
<212> PRT
<213> Homo sapiens

<400> 1520
Met Lys Val Gln Tyr Glu Glu Val Ala Glu Lys Asp Asp Leu Met Gly
  1               5                  10                  15

Val Glu Asp Thr Ala Lys Lys Gly Phe Phe Ser Lys Pro Ser Leu Arg
             20                  25                  30

Ser Arg Asn Thr Ile Phe Thr Leu Gly Thr Arg Gly Ser Val Ile Ser
         35                  40                  45

Pro Thr Glu Leu Glu Ala Pro Ile Leu Val Pro His Thr Ala His Ala
     50                  55                  60

Glu Glu Gln Arg Tyr Pro Phe Glu Ala Leu Phe Arg Ser Gln His Tyr
 65                  70                  75                  80

Ala Leu Leu Asp Asn Ser Cys Arg Glu Tyr Leu Phe Ile Cys Glu Phe
                 85                  90                  95

Phe Val Val Ser Gly Pro Ala Ala His Asp Leu Phe His Ala Val Met
            100                 105                 110

Gly Arg Thr Leu Ser Met Thr Leu Lys His Leu Asp Ser Tyr Leu Ala
        115                 120                 125

Asp Cys Tyr Asp Ala Ile Ala Val Phe Leu Cys Ile His Ile Val Leu
    130                 135                 140

Arg Phe Arg Asn Ile Ala Ala Lys Arg Asp Val Pro Ala Leu Asp Arg
145                 150                 155                 160

Tyr Trp Glu Gln Val Leu Ala Leu Leu Trp Pro Arg Phe Glu Leu Ile
                165                 170                 175

Leu Glu Met Asn Val Gln Ser Val Arg Ser Thr Asp Pro Gln Arg Leu
            180                 185                 190

Gly Gly Leu Asp Thr Arg Pro His Tyr Ile Thr Arg Arg Tyr Ala Glu
        195                 200                 205

Phe Ser Ser Ala Leu Val Ser Ile Asn Gln Thr Ile Pro Asn Glu Arg
    210                 215                 220

Thr Met Gln Leu Leu Gly Gln Leu Gln Val Glu Val Glu Asn Phe Val
225                 230                 235                 240

Leu Arg Val Ala Ala Glu Phe Ser Ser Arg Lys Glu Gln Leu Val Phe
                245                 250                 255

Leu Ile Asn Asn Tyr Asp Met Met Leu Gly Val Leu Met Glu Arg Ala
            260                 265                 270

Ala Asp Asp Ser Lys Glu Val Glu Ser Phe Gln Gln Leu Leu Asn Ala
        275                 280                 285

Arg Thr Gln Glu Phe Ile Glu Glu Leu Leu Ser Pro Pro Phe Gly Gly
    290                 295                 300

Leu Val Ala Phe Val Lys Glu Ala Glu Ala Leu Ile Glu Arg Gly Gln
305                 310                 315                 320

Ala Glu Arg Leu Arg Gly Glu Glu Ala Arg Val Thr Gln Leu Ile Arg
                325                 330                 335

Gly Phe Gly Ser Ser Trp Lys Ser Ser Val Glu Ser Leu Ser Gln Asp
            340                 345                 350

Val Met Arg Ser Phe Thr Asn Phe Arg Asn Gly Thr Ser Ile Ile Gln
        355                 360                 365

Gly Ala Leu Thr Gln Leu Ile Gln Leu Tyr His Arg Phe His Arg Val
    370                 375                 380

Leu Ser Gln Pro Gln Leu Arg Ala Leu Pro Ala Arg Ala Glu Leu Ile
385                 390                 395                 400

Asn Ile His His Leu Met Val Glu Leu Lys Lys His Lys Pro Asn Phe
                405                 410                 415






<210> 1521
<211> 148
<212> PRT
<213> Homo sapiens

<400> 1521
Met Thr Ala Glu Glu Lys Arg Arg Ala His Gln Lys Glu Leu Ala Ala
  1               5                  10                  15

Gln Leu Asn Glu Glu Ala Lys Arg Arg Leu Thr Glu Gln Lys Gly Glu
             20                  25                  30

Gln Gln Ile Gln Lys Ala Arg Lys Ser Asn Val Ser Tyr Lys Asn Pro
         35                  40                  45

Ser Leu Met Pro Lys Glu Pro His Ile Arg Glu Met Lys Ile Tyr Ile
     50                  55                  60

Asp Lys Lys Tyr Glu Thr Val Ile Met Pro Val Phe Gly Ile Ala Thr
 65                  70                  75                  80

Pro Phe His Ile Ala Thr Ile Lys Asn Ile Ser Met Ser Val Glu Gly
                 85                  90                  95

Asp Tyr Thr Tyr Leu Arg Ile Asn Phe Tyr Cys Gln Ala Val Leu Trp
            100                 105                 110

Ala Gly Met Lys Ala Thr Ser Phe Leu Thr Leu Lys Arg Leu Leu Ser
        115                 120                 125

Arg Lys Leu His Thr Glu His Gln Ile Leu Arg His Pro Glu Asn Arg
    130                 135                 140

Gln Tyr Gln Pro 
145



<210> 1522
<211> 297
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (234)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (269)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (275)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (285)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (287)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1522
Met Val Leu Ser Pro Cys His Val Lys Glu Ile Asn Ile Lys Phe Gly
  1               5                  10                  15

Pro Asn Ser Gly Ser Lys Val Pro Leu Ala Thr Val Thr Val Ile Asp
             20                  25                  30

Gln Ser Glu Thr Lys Lys Lys Val Phe Leu Trp Arg Thr Ala Ala Phe
         35                  40                  45

Trp Xaa Phe Thr Val Phe Leu Gly Asp Ile Ile Leu Leu Thr Asp Val
     50                  55                  60

Val Ile His Glu Asp Gln Trp Ile Gly Glu Thr Val Leu Gln Ser Thr
 65                  70                  75                  80

Phe Ser Ser Gln Leu Leu Asn Leu Gly Ser Tyr Ser Ser Ile Gln Pro
                 85                  90                  95

Glu Glu Tyr Ser Ser Val Val Xaa Glu Val Val Leu Gln Asp Leu Leu
            100                 105                 110

Ala Tyr Val Ser Ser Lys His Ser Tyr Leu Arg Asp Leu Pro Pro Arg
        115                 120                 125

Gln Pro Gln Arg Val Asn Ser Ile Asp Phe Val Glu Leu Glu His Leu
    130                 135                 140

Gln Pro Asp Val Leu Val His Ala Val Leu Arg Val Val Asp Phe Thr
145                 150                 155                 160

Ile Leu Thr Glu Ala Val Tyr Ser Tyr Arg Gly Gln Lys Gln Lys Lys
                165                 170                 175

Val Met Leu Thr Val Glu Gln Ala Gln Asp Gln His Tyr Ala Leu Val
            180                 185                 190

Leu Trp Gly Pro Gly Ala Ala Trp Tyr Pro Gln Leu Gln Arg Lys Lys
        195                 200                 205

Gly Tyr Ile Trp Glu Phe Lys Tyr Leu Phe Val Gln Cys Asn Tyr Thr
    210                 215                 220

Leu Glu Asn Leu Glu Leu His Thr Thr Xaa Trp Ser Ser Cys Glu Cys
225                 230                 235                 240

Leu Phe Asp Asp Asp Ile Arg Ala Ile Thr Phe Lys Ala Lys Phe Gln
                245                 250                 255

Lys Ser Ala Pro Ser Phe Val Lys Val Ser Asp Leu Xaa Thr His Leu
            260                 265                 270

Glu Gly Xaa Cys Ser Gly Val Val Leu Ile Lys Pro Xaa Phe Xaa Val
        275                 280                 285

Ala Phe Leu Phe Arg Phe Arg Val Ala 
    290                 295



<210> 1523
<211> 130
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1523
Met Ser Cys Gln Xaa Asn Ala Arg Val Leu Ala Phe Leu Glu Trp Cys
  1               5                  10                  15

Glu Ser Glu Asp Pro Phe Phe Ser His Gly Asn Ser Phe His Gly Thr
             20                  25                  30

Gly Gly Arg Gly Asn Lys Phe Ala Gln Met Arg Tyr Ser Leu Arg Leu
         35                  40                  45

Leu Arg Ala Met Val Tyr Leu Glu Asp Glu Thr Val Asn Lys Asp Leu
     50                  55                  60

Cys Glu Lys Gly Thr Ile Gln Gln Met Ile Gly Ile Phe Lys Asn Ile
 65                  70                  75                  80

Ile Ser Lys Pro Asn Glu Lys Glu Glu Ala Ile Val Leu Glu Ile Gln
                 85                  90                  95

Ser Asp Ile Leu Leu Ile Leu Ser Gly Leu Cys Glu Asn His Ile Gln
            100                 105                 110

Arg Lys Val Cys Met Pro Val Lys Val Leu Phe Arg Ser Pro Ser His
        115                 120                 125

Leu Thr 
    130



<210> 1524
<211> 348
<212> PRT
<213> Homo sapiens

<400> 1524
Met Ala Ala Thr Leu Gly Pro Leu Gly Ser Trp Gln Gln Trp Arg Arg
  1               5                  10                  15

Cys Leu Ser Ala Arg Asp Gly Ser Arg Met Leu Leu Leu Leu Leu Leu
             20                  25                  30

Leu Gly Ser Gly Gln Gly Pro Gln Gln Val Gly Ala Gly Gln Thr Phe
         35                  40                  45

Glu Tyr Leu Lys Arg Glu His Ser Leu Ser Lys Pro Tyr Gln Gly Val
     50                  55                  60

Gly Thr Gly Ser Ser Ser Leu Trp Asn Leu Met Gly Asn Ala Met Val
 65                  70                  75                  80

Met Thr Gln Tyr Ile Arg Leu Thr Pro Asp Met Gln Ser Lys Gln Gly
                 85                  90                  95

Ala Leu Trp Asn Arg Val Pro Cys Phe Leu Arg Asp Trp Glu Leu Gln
            100                 105                 110

Val His Phe Lys Ile His Gly Gln Gly Lys Lys Asn Leu His Gly Asp
        115                 120                 125

Gly Leu Ala Ile Trp Tyr Thr Arg Asn Arg Met Gln Pro Gly Pro Val
    130                 135                 140

Phe Gly Asn Met Asp Lys Phe Val Gly Leu Gly Val Phe Val Asp Thr
145                 150                 155                 160

Tyr Pro Asn Glu Glu Lys Gln Gln Glu Arg Val Phe Pro Tyr Ile Ser
                165                 170                 175

Ala Met Val Asn Asn Gly Ser Leu Ser Tyr Asp His Glu Arg Asp Gly
            180                 185                 190

Arg Pro Thr Glu Leu Gly Gly Cys Thr Ala Ile Val Arg Asn Leu His
        195                 200                 205

Tyr Asp Thr Phe Leu Val Ile Arg Tyr Val Lys Arg His Leu Thr Ile
    210                 215                 220

Met Met Asp Ile Asp Gly Lys His Glu Trp Arg Asp Cys Ile Glu Val
225                 230                 235                 240

Pro Gly Val Arg Leu Pro Arg Gly Tyr Tyr Phe Gly Thr Ser Ser Ile
                245                 250                 255

Thr Gly Asp Leu Ser Asp Asn His Asp Val Ile Ser Leu Lys Leu Phe
            260                 265                 270

Glu Leu Thr Val Glu Arg Thr Pro Glu Glu Glu Lys Leu His Arg Asp
        275                 280                 285

Val Phe Leu Pro Ser Val Asp Asn Met Lys Leu Pro Glu Met Thr Ala
    290                 295                 300

Pro Leu Pro Pro Leu Ser Gly Leu Ala Leu Phe Leu Ile Val Phe Phe
305                 310                 315                 320

Ser Leu Val Phe Ser Val Phe Ala Ile Val Ile Gly Ile Ile Leu Tyr
                325                 330                 335

Asn Lys Trp Gln Glu Gln Ser Arg Lys Arg Phe Tyr 
            340                 345



<210> 1525
<211> 160
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (145)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1525
Met Cys Trp Gln Leu Arg Gly Lys Trp Gln Cys Gly Val Gly Asp Phe
  1               5                  10                  15

Ala Leu Gly Leu Val Pro Phe Arg Pro Pro Gly Leu Pro Leu Pro His
             20                  25                  30

Ser Ser Gln Phe Leu Trp Ser Leu Ser Ile Leu Pro Leu Ser Val His
         35                  40                  45

Pro Cys Thr Xaa His Thr Pro Phe Ser Tyr Ala Phe Gly Val Leu Asp
     50                  55                  60

Gly Asn Leu Gly Gly Glu Arg Lys Asp Arg Ser Gly Leu Pro Gln Pro
 65                  70                  75                  80

Leu Leu Leu Leu Ser Pro Arg Val Arg Ile Ala Gly Ala Pro Pro Pro
                 85                  90                  95

Ser Trp Phe Leu Arg Thr Arg Pro Phe Ser Phe Cys Leu Tyr Leu Leu
            100                 105                 110

Arg Ile Leu Ser Leu Leu Met Trp Leu Thr Pro Leu Pro Pro Leu Pro
        115                 120                 125

Ala Gly Gly Trp Pro Gly Gly Gln Val Pro Ala Gly Ala Val Asn Arg
    130                 135                 140

Xaa Leu Arg Phe Cys Ala Gly Leu Cys Val Cys Cys Ile Ser Val Phe
145                 150                 155                 160






<210> 1526
<211> 142
<212> PRT
<213> Homo sapiens

<400> 1526
Met Asp Ile Pro Lys His Leu Pro Leu Glu Arg Gly Asp Val Thr Arg
  1               5                  10                  15

Arg Ile Leu Trp Gly Leu Trp Thr Ser Ser Arg Cys Val Phe Ala Glu
             20                  25                  30

Arg Thr Gly Glu Met Glu Thr Pro Gly Ala Val Gly Ser Gln Gly Cys
         35                  40                  45

Leu Val Asn Ser Ala Leu Thr Arg Thr Gln Gly Ser Ala Pro Ala Leu
     50                  55                  60

Ser Ser Tyr Leu Cys Leu Leu Ser Ile Cys Gly Val Ser Gly Cys Arg
 65                  70                  75                  80

Pro Leu Cys Cys Gly Gly Gly Glu Pro Gly Arg Gly Arg Ala Arg Gln
                 85                  90                  95

Gly Pro Gln Ser Trp Ala Thr Gln Trp Val Leu Gly Leu Ala Pro Lys
            100                 105                 110

Leu Leu Val Gln Gln Pro Leu Val Leu Ser Pro Arg Lys Ser Gly Arg
        115                 120                 125

Leu Asp Ser Arg Thr Gly Val Asn Val Lys Ile Asn Ile Ala 
    130                 135                 140



<210> 1527
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1527
Met Gly Ile Gln Thr Val Arg Pro Ser Phe Ser Ile Leu His Trp Gly
  1               5                  10                  15

Thr Pro Pro His Leu Val Leu Ala Thr Gln Leu Arg Thr Arg Gly Cys
             20                  25                  30

Arg Cys Arg Pro Arg Pro Ala Gly Ser Gly Pro Thr Val Asp Ala Gly
         35                  40                  45

Val Pro Ile Pro His Ile Arg Ala Arg Xaa Ser Ala Arg Leu Pro Leu
     50                  55                  60

Cys Pro Trp His Ala Ser Ala Leu Glu Leu Gly Ile Ala Thr Pro Gly
 65                  70                  75                  80

Thr Val Thr Thr Gln Ala Pro Gly Ser Tyr Pro Ala Trp Arg Ser Arg
                 85                  90                  95

Cys Leu Leu Tyr Pro Gln Ser Pro Val Leu Leu Ala Ser Leu Gly Val
            100                 105                 110

Gly Leu Val Asn Leu Leu Gly Trp Leu Xaa Ala Pro Asn Trp Phe Gly
        115                 120                 125

Ser Pro Xaa Gly Xaa Ser His 
    130                 135



<210> 1528
<211> 101
<212> PRT
<213> Homo sapiens

<400> 1528
Met Gly Lys Phe Leu Gly Lys Thr Lys Thr Gln Pro Gln Gly Gln Val
  1               5                  10                  15

Val Ile Phe Ser Glu Lys Gly Lys Ala Ile Ile Tyr Leu Ser Leu Pro
             20                  25                  30

Arg Thr Val Pro Ile Tyr Thr Cys Ile Phe Ser Gln Ser Val Gly Cys
         35                  40                  45

Leu Phe Ile Leu Leu Ile Ile Ser Phe Asn Phe Leu Leu Phe Ile Tyr
     50                  55                  60

Phe Ile Glu Thr Asp Leu Ile Met Leu Pro Arg Val Ile Leu Asp Leu
 65                  70                  75                  80

Leu Ala Ser Ser Asp Pro Pro Thr Leu Val Ser Gln Ser Ala Gly Ile
                 85                  90                  95

Thr Asp Val Asn Tyr 
            100



<210> 1529
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1529
Met Asn Pro Ile Ser Ala Thr Cys Gln Tyr Leu Leu Phe Lys Ala Pro
  1               5                  10                  15

Phe Glu Thr Gln Phe Cys Ala Lys Ser Ser Gly Ser Asn Tyr Leu Lys
             20                  25                  30

Gln Ala Asp Leu Ala Ile Phe Lys Gln Thr Phe Pro Val Ile Leu Val
         35                  40                  45

Leu Val Leu Leu Leu His Val Met Lys Asp Leu Gly Phe Thr Glu Asn
     50                  55                  60

Ser Ser Arg Gly Leu Gly Phe Xaa Thr Xaa Lys Val Ser Xaa Xaa Gly
 65                  70                  75                  80

Pro Ile Val Asp His Pro Arg Ala Leu Ser Ser Val Leu Val Lys Val
                 85                  90                  95

Glu Thr Ala Val Pro His Pro Pro Ser Phe 
            100                 105



<210> 1530
<211> 350
<212> PRT
<213> Homo sapiens

<400> 1530
Met Ala Val Phe Val Val Leu Leu Ala Leu Val Ala Gly Val Leu Gly
  1               5                  10                  15

Asn Glu Phe Ser Ile Leu Lys Ser Pro Gly Ser Val Val Phe Arg Asn
             20                  25                  30

Gly Asn Trp Pro Ile Pro Gly Glu Arg Ile Pro Asp Val Ala Ala Leu
         35                  40                  45

Ser Met Gly Phe Ser Val Lys Glu Asp Leu Ser Trp Pro Gly Leu Ala
     50                  55                  60

Val Gly Asn Leu Phe His Arg Pro Arg Ala Thr Val Met Val Met Val
 65                  70                  75                  80

Lys Gly Val Asn Lys Leu Ala Leu Pro Pro Gly Ser Val Ile Ser Tyr
                 85                  90                  95

Pro Leu Glu Asn Ala Val Pro Phe Ser Leu Asp Ser Val Ala Asn Ser
            100                 105                 110

Ile His Ser Leu Phe Ser Glu Glu Thr Pro Val Val Leu Gln Leu Ala
        115                 120                 125

Pro Ser Glu Glu Arg Val Tyr Met Val Gly Lys Ala Asn Ser Val Phe
    130                 135                 140

Glu Asp Leu Ser Val Thr Leu Arg Gln Leu Arg Asn Arg Leu Phe Gln
145                 150                 155                 160

Glu Asn Ser Val Leu Ser Ser Leu Pro Leu Asn Ser Leu Ser Arg Asn
                165                 170                 175

Asn Glu Val Asp Leu Leu Phe Leu Ser Glu Leu Gln Val Leu His Asp
            180                 185                 190

Ile Ser Ser Leu Leu Ser Arg His Lys His Leu Ala Lys Asp His Ser
        195                 200                 205

Pro Asp Leu Tyr Ser Leu Glu Leu Ala Gly Leu Asp Glu Ile Gly Lys
    210                 215                 220

Arg Tyr Gly Glu Asp Ser Glu Gln Phe Arg Asp Ala Ser Lys Ile Leu
225                 230                 235                 240

Val Asp Ala Leu Gln Lys Phe Ala Asp Asp Met Tyr Ser Leu Tyr Gly
                245                 250                 255

Gly Asn Ala Val Val Glu Leu Val Thr Val Lys Ser Phe Asp Thr Ser
            260                 265                 270

Leu Ile Arg Lys Thr Arg Thr Ile Leu Glu Ala Lys Gln Ala Lys Asn
        275                 280                 285

Pro Ala Ser Pro Tyr Asn Leu Ala Tyr Lys Tyr Asn Phe Glu Tyr Ser
    290                 295                 300

Val Val Phe Asn Met Val Leu Trp Ile Met Ile Ala Leu Ala Leu Ala
305                 310                 315                 320

Val Ile Ile Thr Ser Tyr Asn Ile Trp Asn Met Asp Pro Gly Tyr Asp
                325                 330                 335

Ser Ile Ile Tyr Arg Met Thr Asn Gln Lys Ile Arg Met Asp 
            340                 345                 350



<210> 1531
<211> 158
<212> PRT
<213> Homo sapiens

<400> 1531
Met Val Val Phe Gly Tyr Glu Ala Gly Thr Lys Pro Arg Asp Ser Gly
  1               5                  10                  15

Val Val Pro Val Gly Thr Glu Glu Ala Pro Lys Val Phe Lys Met Ala
             20                  25                  30

Ala Ser Met His Gly Gln Pro Ser Pro Ser Leu Glu Asp Ala Lys Leu
         35                  40                  45

Arg Arg Pro Met Val Ile Glu Ile Ile Glu Lys Asn Phe Asp Tyr Leu
     50                  55                  60

Arg Lys Glu Met Thr Gln Asn Ile Tyr Gln Met Ala Thr Phe Gly Thr
 65                  70                  75                  80

Thr Ala Gly Phe Ser Gly Ile Phe Ser Asn Phe Leu Phe Arg Arg Cys
                 85                  90                  95

Phe Lys Val Lys His Asp Ala Leu Lys Thr Tyr Ala Ser Leu Ala Thr
            100                 105                 110

Leu Pro Phe Leu Ser Thr Val Val Thr Asp Lys Leu Phe Val Ile Asp
        115                 120                 125

Ala Leu Tyr Ser Asp Asn Ile Ser Lys Glu Asn Cys Val Phe Arg Ser
    130                 135                 140

Ser Leu Ile Gly Ile Val Cys Gly Val Ser Ile Pro Val Leu 
145                 150                 155



<210> 1532
<211> 106
<212> PRT
<213> Homo sapiens

<400> 1532
Met Asp Lys Asn Gln Lys Leu Ser Val Val Arg Glu Leu Met Leu Arg
  1               5                  10                  15

Tyr Gln His Gly Leu Glu Phe Gly Lys Thr Cys Leu Lys Thr Glu Leu
             20                  25                  30

Gln Phe Ser Asp Tyr Tyr Cys Leu Leu Ala Val His Ala Leu Ile Asp
         35                  40                  45

Val Trp Arg Glu Thr Gly Asp Glu Thr Thr Val Trp Gln Ala Leu Thr
     50                  55                  60

Leu Leu Glu Glu Gly Leu Thr His Ser Pro Ser Asn Ala Gln Phe Lys
 65                  70                  75                  80

Leu Leu Leu Val Arg Ile Tyr Cys Met Leu Gly Ala Phe Glu Pro Val
                 85                  90                  95

Val Asp Leu Tyr Ser Ser Leu Asp Ala Lys 
            100                 105



<210> 1533
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1533
Met Thr Phe Glu Thr Val Gly Lys Lys Thr Ile Asn Pro Ile Ile Cys
  1               5                  10                  15

Pro Ala Phe Met Gly Xaa Met Ile Ile His Leu Ala Phe Val Leu Leu
             20                  25                  30

Cys Phe Lys Asp Cys Gln Asn Lys Asn Asn Val Phe Ile Ala Phe Tyr
         35                  40                  45

Phe Leu Ile Cys Gln Leu Lys Thr Thr Gln Lys Asn Thr Thr Glu Glu
     50                  55                  60

Phe Ile Gln Asn Leu Tyr Tyr Leu Ser Phe Gln Asn Phe Phe Leu Leu
 65                  70                  75                  80

Asn Phe Lys Arg Ala Val Lys Val Ser Val Arg Asn Phe Pro Pro Glu
                 85                  90                  95

Thr Ser Leu Gly Ser Leu Leu Phe Gly Gly Cys Leu Val Val Cys Asn
            100                 105                 110

Leu Lys Ile 
        115



<210> 1534
<211> 204
<212> PRT
<213> Homo sapiens

<400> 1534
Met Ala Lys Val Gln Val Asn Asn Val Val Val Leu Asp Asn Pro Ser
  1               5                  10                  15

Pro Phe Tyr Asn Pro Phe Gln Phe Glu Ile Thr Phe Glu Cys Ile Glu
             20                  25                  30

Asp Leu Ser Glu Asp Leu Glu Trp Lys Ile Ile Tyr Val Gly Ser Ala
         35                  40                  45

Glu Ser Glu Glu Tyr Asp Gln Val Leu Asp Ser Val Leu Val Gly Pro
     50                  55                  60

Val Pro Ala Gly Arg His Met Phe Val Phe Gln Ala Asp Ala Pro Asn
 65                  70                  75                  80

Pro Gly Leu Ile Pro Asp Ala Asp Ala Val Gly Val Thr Val Val Leu
                 85                  90                  95

Ile Thr Cys Thr Tyr Arg Gly Gln Glu Phe Ile Arg Val Gly Tyr Tyr
            100                 105                 110

Val Asn Asn Glu Tyr Thr Glu Thr Glu Leu Arg Glu Asn Pro Pro Val
        115                 120                 125

Lys Pro Asp Phe Ser Lys Leu Gln Arg Asn Ile Leu Ala Ser Asn Pro
    130                 135                 140

Arg Val Thr Arg Phe His Ile Asn Trp Glu Asp Asn Thr Glu Lys Leu
145                 150                 155                 160

Glu Asp Ala Glu Ser Ser Asn Pro Asn Leu Gln Ser Leu Leu Ser Thr
                165                 170                 175

Asp Ala Leu Pro Ser Ala Ser Lys Gly Trp Ser Thr Ser Glu Asn Ser
            180                 185                 190

Leu Asn Val Met Leu Glu Ser His Met Asp Cys Met 
        195                 200



<210> 1535
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1535
Met Pro Arg Ala Arg Thr His Xaa Gln Arg Leu Ser Trp Ser Val Phe
  1               5                  10                  15

Met Gln Met Gly Thr Ser Asn His Trp Ser His Leu Ser Phe Val Ser
             20                  25                  30

Glu Ser Leu Gly Gly Val Cys Gly His Glu Arg Gly Arg Glu Trp Arg
         35                  40                  45

Val Arg Leu Pro His Glu Ala Ser Pro Glu Leu Leu Pro Ala Ala Cys
     50                  55                  60

Ser Glu His Pro Gly Ser Thr Val Gln Ser Ala Gln Asp Ser Gly Ser
 65                  70                  75                  80

Arg His Gly Arg Leu Gln Leu Pro Gln Arg Thr Val Asp Arg Glu Xaa
                 85                  90                  95

Gln Pro Arg Ile Pro Leu Ser Met Pro Gly Met Thr Leu Ile Xaa Lys
            100                 105                 110

Ser Phe Ile Phe Glu Phe Val Ala Val Val His Phe Leu Pro Thr His
        115                 120                 125

Ser Ile Asn Leu Thr Glu Leu 
    130                 135



<210> 1536
<211> 121
<212> PRT
<213> Homo sapiens

<400> 1536
Met Lys Asn Glu Lys Leu Leu Ser Lys Ala Ser Glu Pro Lys Tyr Gln
  1               5                  10                  15

Leu Phe Val Pro Gln Leu Val Thr Gly Arg Cys Ala Thr Arg Ala Phe
             20                  25                  30

His Arg Lys Ser His Ser Leu Asp Leu Asn Ile Ser Glu Lys Leu Thr
         35                  40                  45

Leu Leu Pro Thr Leu Tyr Glu Ile His Ser Lys Thr Thr Ala Tyr Ser
     50                  55                  60

Arg Leu Asn Glu Thr Gln Pro Ile Asp Leu Ser Gly Leu Leu Tyr Asn
 65                  70                  75                  80

Leu Val Lys Ile Ala Ile Pro Phe Arg Ile His Pro Val Leu Ile Leu
                 85                  90                  95

Val Cys Cys Cys Lys Asp Phe Gln Trp Pro Pro Met Arg Pro Arg His
            100                 105                 110

Lys Glu Glu Glu Asn Phe Ser Val Val 
        115                 120



<210> 1537
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1537
Met Arg Thr Tyr His Val Gly Val Leu Gly Lys Ser Gly Lys Tyr Asp
  1               5                  10                  15

Ser Val Leu His Trp Ala Leu Ile Leu Ser Cys Tyr Ile Cys Thr Ile
             20                  25                  30

Glu Tyr Phe Arg Asn Tyr Met Lys His Glu Thr Val Phe Ala Ile Phe
         35                  40                  45

Phe Lys Leu Gly Ile Trp Phe Leu Lys Ile Tyr Leu Lys Gln Ser Arg
     50                  55                  60

Ile Phe Leu Val Gln Ser Val Ser Cys Gly Ile Ser Xaa Tyr Phe Tyr
 65                  70                  75                  80

His Ile Leu Arg Thr Leu Arg Arg Leu Ile Val Asn Asn Leu Phe Asp
                 85                  90                  95

Trp Cys Ser Xaa Asn Pro 
            100



<210> 1538
<211> 109
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1538
Met Leu Leu Glu Leu Ser Glu Glu His Lys Glu His Leu Ala Phe Leu
  1               5                  10                  15

Pro Gln Val Asp Ser Ala Gly Gln Arg Ala Trp Gly Arg Cys Ser Val
             20                  25                  30

Gly Trp Gly Gly Gly Gln Arg Gln Arg Leu Ala Leu Asn Ser Leu Leu
         35                  40                  45

Thr Phe Ile Ala Val Val Ala Glu Phe Gly Arg Ile Ala Val Glu Phe
     50                  55                  60

Leu Arg Arg Gly Ala Asn Pro Lys Ile Tyr Xaa Gly Ala Ala Ser Lys
 65                  70                  75                  80

Lys Gly Lys Gly Lys Ala Pro Gln Ala Ser Arg Ala Val Ala Ser His
                 85                  90                  95

Ser Leu Ser Pro Gly Arg Glu Thr Asp Tyr Cys Glu Xaa 
            100                 105



<210> 1539
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1539
Met Phe Ser Phe Glu Thr Pro Val Leu Val Leu Cys Trp Asn Thr Val
  1               5                  10                  15

Leu Gln Thr Val Phe Thr Trp Asp Ala Ile Tyr Leu Leu His Cys Ser
             20                  25                  30

Leu Cys Lys Thr Val Ala Arg Gly Trp Gln Thr Pro Pro Thr Xaa Trp
         35                  40                  45

Cys Gln Asn Pro Gln Asp Gln Arg Ser Ile Arg Ser Pro Ala Asp Leu
     50                  55                  60

Gln Trp Leu Thr Ala Gly Arg Pro Cys Ala Gln Pro Gly His Val Ala
 65                  70                  75                  80

Val Thr Val Cys Ser Val Ala Pro Val Ala Cys Pro Cys Leu Ala Ala
                 85                  90                  95

Arg Gln Gly Arg Val Trp Val Trp Gly Cys Gln Val Gly Arg Ser Cys
            100                 105                 110

Cys Cys Pro Asp Phe Gly Ile Cys Gln Pro Val Pro Ala Thr Gly Gln
        115                 120                 125

Ser Leu Pro Pro Thr Leu Lys 
    130                 135



<210> 1540
<211> 168
<212> PRT
<213> Homo sapiens

<400> 1540
Met Leu Pro Pro Ala His His Gln Ala Phe Val Arg His Arg Leu Glu
  1               5                  10                  15

Glu Ala Phe Arg Val Ala Leu Val Gly His Arg His Pro Leu Pro Val
             20                  25                  30

Leu Ala Tyr Val Arg Leu Thr His Arg Arg Ser Gly Arg Phe Leu Ser
         35                  40                  45

Gln Asp Asp Leu Val Gln Ser Ile Gly Val Ser Ala Ala Leu Gly Ala
     50                  55                  60

Ala Gly Val Val Leu Trp Gly Asp Leu Ser Leu Ser Ser Ser Glu Glu
 65                  70                  75                  80

Glu Cys Trp His Leu His Asp Tyr Leu Val Asp Thr Leu Gly Pro Tyr
                 85                  90                  95

Val Ile Asn Val Thr Arg Ala Ala Met Ala Cys Ser His Gln Arg Cys
            100                 105                 110

His Gly His Gly Arg Cys Ala Arg Arg Asp Pro Gly Gln Met Glu Ala
        115                 120                 125

Phe Leu His Leu Trp Pro Asp Gly Ser Leu Gly Asp Trp Lys Ser Phe
    130                 135                 140

Ser Cys His Cys Tyr Trp Gly Trp Ala Gly Pro Thr Cys Gln Glu Pro
145                 150                 155                 160

Arg Pro Gly Pro Lys Glu Ala Val 
                165



<210> 1541
<211> 213
<212> PRT
<213> Homo sapiens

<400> 1541
Met Lys Leu Asn Arg Gln Leu Ile Phe Cys Thr Leu Ala Ala Leu Ala
  1               5                  10                  15

Glu Glu Arg Lys Pro Leu Glu Cys Leu Asp Ala Phe Gly Ala Thr Gly
             20                  25                  30

Ile Met Gly Leu Gln Trp Ala Lys His Leu Gly Asn Ala Val Lys Val
         35                  40                  45

Thr Ile Asn Asp Leu Asn Glu Asn Ser Val Thr Leu Ile Gln Glu Asn
     50                  55                  60

Cys His Leu Asn Lys Leu Lys Val Val Val Asp Ser Lys Glu Lys Glu
 65                  70                  75                  80

Lys Ser Asp Asp Ile Leu Glu Glu Gly Glu Lys Asn Leu Gly Asn Ile
                 85                  90                  95

Lys Val Thr Lys Met Asp Ala Asn Val Leu Met His Leu Arg Ser Phe
            100                 105                 110

Asp Phe Ile His Leu Asp Pro Phe Gly Thr Ser Val Asn Tyr Leu Asp
        115                 120                 125

Ser Ala Phe Arg Asn Ile Arg Asn Leu Gly Ile Val Ser Val Thr Ser
    130                 135                 140

Thr Asp Ile Ser Ser Leu Tyr Ala Lys Ala Gln His Val Ala Arg Arg
145                 150                 155                 160

His Tyr Gly Cys Asn Ile Val Arg Thr Glu Tyr Tyr Lys Glu Leu Ala
                165                 170                 175

Ala Arg Ile Val Val Ala Ala Val Ala Arg Ala Ala Ala Arg Cys Asn
            180                 185                 190

Lys Gly Ile Glu Val Leu Phe Ala Val Ala Leu Glu His Phe Val Leu
        195                 200                 205

Val Val Val Arg Val 
    210



<210> 1542
<211> 218
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (199)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (213)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1542
Met Ala Ala Thr Phe Phe Gly Glu Val Val Lys Ala Pro Cys Arg Ala
  1               5                  10                  15

Gly Thr Glu Asp Glu Glu Glu Glu Glu Glu Gly Arg Arg Glu Thr Pro
             20                  25                  30

Glu Asp Arg Glu Val Arg Leu Gln Leu Ala Arg Lys Arg Glu Val Arg
         35                  40                  45

Leu Leu Arg Arg Gln Thr Lys Thr Ser Leu Glu Val Ser Leu Leu Glu
     50                  55                  60

Lys Tyr Pro Cys Ser Lys Phe Ile Ile Ala Ile Gly Asn Asn Ala Val
 65                  70                  75                  80

Ala Phe Leu Ser Ser Phe Val Met Asn Ser Gly Val Trp Glu Glu Val
                 85                  90                  95

Gly Cys Ala Lys Leu Trp Asn Glu Trp Cys Arg Thr Thr Asp Thr Thr
            100                 105                 110

His Leu Ser Ser Thr Glu Ala Phe Cys Val Phe Tyr His Leu Lys Ser
        115                 120                 125

Asn Pro Ser Val Phe Leu Cys Gln Cys Ser Cys Tyr Val Ala Glu Asp
    130                 135                 140

Gln Gln Tyr Gln Trp Leu Glu Lys Val Phe Xaa Leu Leu Ser Lys Glu
145                 150                 155                 160

Glu His Ala Asp Asn Tyr Ser Xaa His Val Asp Met Phe Thr Gly Leu
                165                 170                 175

Xaa Lys Pro Gln Asn Pro Pro Gly Gln Pro Phe Leu Ser Pro Phe Pro
            180                 185                 190

Trp Arg Arg Pro Leu Lys Xaa Arg Ile Pro Lys Xaa Arg Ala Trp Phe
        195                 200                 205

Gly Xaa Ile Gly Xaa Gly Thr Thr Gly Leu 
    210                 215



<210> 1543
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1543
Met Ala Leu Thr Gly Ala Ser Asp Pro Ser Ala Glu Ala Glu Ala Asn
  1               5                  10                  15

Gly Glu Lys Pro Phe Leu Leu Arg Ala Leu Gln Ile Ala Leu Val Val
             20                  25                  30

Ser Leu Tyr Trp Val Thr Ser Ile Ser Met Val Phe Leu Asn Lys Tyr
         35                  40                  45

Leu Leu Asp Ser Pro Ser Leu Arg Leu Asp Thr Pro Ile Phe Val Thr
     50                  55                  60

Phe Tyr Gln Cys Leu Val Thr Thr Leu Leu Cys Lys Gly Leu Ser Ala
 65                  70                  75                  80

Leu Ala Ala Cys Cys Pro Gly Ala Val Asp Phe Pro Ser Leu Arg Leu
                 85                  90                  95

Asp Leu Xaa Val Ala Arg Ser Val Leu Pro Leu Ser Val Val Phe Ile
            100                 105                 110

Gly Met Ile Thr Phe Asn Asn Leu Cys Xaa Ser Thr Ser Val Trp Pro
        115                 120                 125

Ser Thr Met Trp Ala Ala His Ser Pro Pro Xaa Ser Thr Cys Cys Ser
    130                 135                 140

Pro Thr Cys Cys Ser Xaa Xaa Pro Pro Pro Ser Met Pro Cys Phe Thr
145                 150                 155                 160

Cys Gly Ile His His Arg Gly Leu Leu Ala Trp Cys Gly Thr Arg Arg
                165                 170                 175

Gly Gln Lys Ala Pro Cys Arg 
            180



<210> 1544
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1544
Met Glu Leu Leu Met Phe Ile Leu Val Arg His Met Pro His Leu Ser
  1               5                  10                  15

Thr Lys Val Ser Asp Ser Pro Ser His Ile Ala Thr Lys Thr Arg Leu
             20                  25                  30

Ser Glu Xaa Ser Ala Arg Leu Val Ala Ala Thr Val Thr Ile Leu Ser
         35                  40                  45

Asp Leu Pro Ser Leu Cys Ser Pro Ala Gly Cys Met Thr Ile Leu Pro
     50                  55                  60

Thr Ile Leu Phe Leu Ile Ala Arg Ile Leu Lys Asp Thr Ala Ile Lys
 65                  70                  75                  80

Ser Ala Asp Asn Gln Val Pro Pro Pro Val Ser Ala Ala Leu Gln Gly
                 85                  90                  95

Ile Lys Ser Ile Val Thr Leu Ser Met Ala Lys Thr Glu Ala Gly Val
            100                 105                 110

Gln Lys Gln Trp Thr Ala Leu 
        115



<210> 1545
<211> 273
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1545
Met Gln Asn Leu Gly Arg Val Leu Lys Ala Trp Val Val Ser His Pro
  1               5                  10                  15

Asp Leu Val Tyr Trp Gln Gly Leu Asp Ser Leu Cys Ala Pro Phe Leu
             20                  25                  30

Tyr Leu Asn Phe Asn Asn Glu Ala Leu Ala Tyr Ala Cys Met Ser Ala
         35                  40                  45

Phe Ile Pro Lys Tyr Leu Tyr Asn Phe Phe Leu Lys Asp Asn Ser His
     50                  55                  60

Val Ile Gln Glu Tyr Leu Thr Val Phe Ser Gln Met Ile Ala Phe His
 65                  70                  75                  80

Asp Pro Glu Leu Ser Asn His Leu Asn Glu Ile Gly Phe Ile Pro Asp
                 85                  90                  95

Leu Tyr Ala Ile Pro Trp Phe Leu Thr Met Phe Thr His Val Phe Pro
            100                 105                 110

Leu His Lys Ile Phe His Leu Trp Asp Thr Leu Leu Leu Gly Asn Ser
        115                 120                 125

Ser Phe Pro Phe Cys Ile Gly Val Ala Ile Leu Gln Gln Leu Arg Asp
    130                 135                 140

Arg Leu Leu Ala Asn Gly Phe Xaa Glu Cys Ile Leu Leu Phe Ser Asp
145                 150                 155                 160

Leu Pro Glu Ile Asp Ile Glu Arg Cys Val Arg Glu Ser Ile Asn Leu
                165                 170                 175

Phe Cys Trp Thr Pro Lys Ser Ala Thr Tyr Arg Gln His Ala Gln Pro
            180                 185                 190

Pro Lys Pro Ser Ser Asp Ser Ser Gly Gly Arg Ser Ser Ala Pro Tyr
        195                 200                 205

Phe Ser Ala Glu Cys Pro Asp Pro Pro Lys Thr Asp Leu Ser Arg Glu
    210                 215                 220

Ser Ile Pro Leu Asn Asp Leu Lys Ser Glu Val Ser Pro Arg Ile Ser
225                 230                 235                 240

Ala Glu Asp Leu Ile Asp Leu Cys Glu Leu Thr Val Thr Gly His Phe
                245                 250                 255

Lys Thr Pro Ser Lys Lys Thr Lys Ser Ser Lys Pro Lys Leu Leu Val
            260                 265                 270

Val 




<210> 1546
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1546
Met Ala Lys Ala Leu Thr Thr Met Gln Glu Gln Ile Asp Ser Leu Ala
  1               5                  10                  15

Ala Val Val Leu Gln Asn Arg Arg Gly Leu Asp Met Leu Thr Ala Ala
             20                  25                  30

Gln Gly Gly Ile Cys Leu Ala Leu Asp Glu Lys Cys Cys Phe Trp Val
         35                  40                  45

Asn Gln Ser Gly Xaa Val Gln Asp Asn Ile Arg Gln Leu Leu Asn Gln
     50                  55                  60

Ala Ser Ser Leu Arg Glu Arg Ala Xaa Gln Gly Xaa Leu Xaa Trp Xaa
 65                  70                  75                  80

Gly Thr Trp Lys Trp Xaa Ser Trp Val Leu Pro Leu Xaa Gly Pro Leu
                 85                  90                  95

Val Ser Leu Leu Leu Leu Leu Leu Phe Gly Pro Cys Leu Leu Asn Leu
            100                 105                 110

Ile Thr Gln Phe Val Ser Ser Arg Leu Gln Ala Ile Lys Leu Gln Thr
        115                 120                 125

Asn Leu Ser Ala Gly Arg His Pro Arg Asn Ile Gln Glu Ser Pro Phe
    130                 135                 140






<210> 1547
<211> 110
<212> PRT
<213> Homo sapiens

<400> 1547
Met Val Gly Ile Ile Tyr Lys Pro Lys Thr Lys Glu Thr Arg Glu Thr
  1               5                  10                  15

Tyr Glu Val Leu Leu Ser Phe Ile Gln Ala Ala Leu Gly Asp Gln Pro
             20                  25                  30

Arg Asp Ile Leu Cys Gly Ala Ala Asp Glu Val Leu Ala Val Leu Lys
         35                  40                  45

Asn Glu Lys Leu Arg Asp Lys Glu Arg Arg Lys Glu Ile Asp Leu Leu
     50                  55                  60

Leu Gly Gln Thr Asp Asp Thr Arg Tyr His Val Leu Val Asn Leu Gly
 65                  70                  75                  80

Lys Lys Ile Thr Asp Tyr Gly Gly Asp Lys Glu Ile Gln Asn Met Gly
                 85                  90                  95

Lys Cys Ala Leu Tyr Val Leu Ile Met Phe Ile Gly Cys Cys 
            100                 105                 110



<210> 1548
<211> 110
<212> PRT
<213> Homo sapiens

<400> 1548
Met Gln Lys Ala Gly Arg His His Pro Leu Arg Ala Pro Pro Ala Ser
  1               5                  10                  15

Ser Gln Tyr Trp Ile Gly Leu Ala Trp Leu Val Ala Val Trp Glu Lys
             20                  25                  30

Gln Pro Lys Arg Leu Val Tyr Phe Asn Thr Lys Leu Asp His Gly Pro
         35                  40                  45

Phe Pro Thr Gly Leu Phe Lys Gly Leu Tyr Gly Ile His Cys Leu Val
     50                  55                  60

Ser Phe Phe Ala Val His His Ser Lys Glu Cys His Leu His Pro Lys
 65                  70                  75                  80

Pro Pro Phe Ser His Glu Gly Lys Ser Lys Lys Gly Leu Gln Phe Leu
                 85                  90                  95

Leu Lys Gly Val Pro Phe Val Gly Arg Val Ile Asn Thr Ile 
            100                 105                 110



<210> 1549
<211> 110
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1549
Met Thr Asn Val Tyr Phe Lys Lys Glu Asn Asp Ile Ile Xaa Asn Gly
  1               5                  10                  15

Thr Leu Trp Lys Glu Gly Arg Ile Lys Leu Cys Xaa Val His His Leu
             20                  25                  30

Ala Asp His Gln Lys His Ser Ala Ala Arg Asp Arg Arg Trp Val Cys
         35                  40                  45

Pro Arg Ser Arg Arg Pro Ala His Leu Lys Pro Arg Ser Val Pro Pro
     50                  55                  60

Ser Gly Leu Phe Ile Val Glu Ser Val Phe Ile Cys Phe Ile Met Lys
 65                  70                  75                  80

Asn Thr Ile Cys Lys Gly Ile Leu Ile Cys Ile Phe Ile Gln Ala His
                 85                  90                  95

Lys Asn Ser Thr Trp Pro Gly Ser Arg Met His Cys Ile Val 
            100                 105                 110



<210> 1550
<211> 193
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (171)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (184)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1550
Met Phe Thr Cys Phe Pro Lys Cys Leu Gly Phe Ser Pro Xaa Val Asn
  1               5                  10                  15

Val Thr Val Ser Pro Arg Ser Glu Glu Ser His Thr Thr Thr Val Ser
             20                  25                  30

Gly Gly Asn Gly Ser Val Phe Gln Ala Gly Pro Gln Leu Gln Ala Leu
         35                  40                  45

Ala Asn Leu Glu Ala Xaa Arg Gly Ser Ile Gly Ala Ala Leu Ser Ser
     50                  55                  60

Arg Asp Val Ser Gly Leu Pro Val Tyr Ala Gln Ser Gly Glu Pro Arg
 65                  70                  75                  80

Arg Leu Thr Gln Ala Gln Val Ala Ala Phe Pro Gly Glu Asn Ala Leu
                 85                  90                  95

Glu His Ser Ser Asp Gln Asp Thr Trp Asp Ser Leu Arg Ser Pro Gly
            100                 105                 110

Phe Cys Ser Pro Leu Ser Ser Gly Gly Gly Ala Glu Ser Leu Pro Pro
        115                 120                 125

Gly Gly Pro Gly His Ala Glu Ala Gly His Leu Gly Lys Val Cys Asp
    130                 135                 140

Phe His Leu Asn His Gln Gln Pro Ser Pro Thr Ser Val Leu Pro Asn
145                 150                 155                 160

Arg Gly Gly Gln Pro Leu Arg Phe Glu Lys Xaa Leu Phe Cys Trp Ile
                165                 170                 175

Ser Xaa Ala Leu Gly Leu Leu Xaa Thr Gly Ile Val Ala Pro Ser Gln
            180                 185                 190

Gly 




<210> 1551
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1551
Met Val Ser Val Thr Met Ala Thr Ser Glu Trp Ile Gln Phe Phe Lys
  1               5                  10                  15

Glu Ala Gly Ile Pro Pro Gly Pro Ala Val Asn Tyr Ala Val Met Phe
             20                  25                  30

Val Asp Asn Arg Ile Gln Lys Ser Met Leu Leu Asp Leu Asn Lys Glu
         35                  40                  45

Ile Met Asn Glu Leu Gly Val Thr Val Val Gly Asp Ile Ile Ala Ile
     50                  55                  60

Leu Lys His Ala Lys Val Val His Arg Gln Asp Met Cys Lys Ala Ala
 65                  70                  75                  80

Thr Glu Ser Val Pro Cys Ser Pro Ser Pro Leu Ala Gly Glu Ile Arg
                 85                  90                  95

Arg Gly Thr Ser Ala Ala Ser Arg Met Ile Thr Asn Ser Leu Asn His
            100                 105                 110

Asp Ser Pro Pro Ser Thr Pro Pro Arg Arg Pro Asp Thr Ser Thr Ser
        115                 120                 125

Lys Ile Ser Gly His Cys Val Gln Gln Asp Ser Ser Lys Xaa Cys Gln
    130                 135                 140

Gly His Cys 
145



<210> 1552
<211> 127
<212> PRT
<213> Homo sapiens

<400> 1552
Met Lys Gln Ile Thr Gln Leu Leu Pro Glu Asp Leu Arg Lys Glu Leu
  1               5                  10                  15

Tyr Glu Leu Trp Glu Glu Tyr Glu Thr Gln Ser Ser Ala Glu Ala Lys
             20                  25                  30

Phe Val Lys Gln Leu Asp Gln Cys Glu Met Ile Leu Gln Ala Ser Glu
         35                  40                  45

Tyr Glu Asp Leu Glu His Lys Pro Gly Arg Leu Gln Asp Phe Tyr Asp
     50                  55                  60

Ser Thr Ala Gly Lys Phe Asn His Pro Glu Ile Val Gln Leu Val Ser
 65                  70                  75                  80

Glu Leu Glu Ala Glu Arg Ser Thr Asn Ile Ala Ala Val Pro Val Ser
                 85                  90                  95

His Thr Pro Glu Thr Leu Ser Lys Leu Leu His Ser Cys Asn Lys His
            100                 105                 110

Tyr Phe Ser Ile Ser Leu Tyr Cys Val Leu Pro Leu Leu Val Cys 
        115                 120                 125



<210> 1553
<211> 121
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1553
Met Leu His Thr Thr Gln Leu Tyr Gln His Val Pro Glu Thr Arg Trp
  1               5                  10                  15

Pro Ile Val Tyr Ser Pro Arg Tyr Asn Ile Thr Phe Met Gly Leu Glu
             20                  25                  30

Lys Leu His Pro Phe Asp Ala Gly Lys Trp Gly Lys Val Ile Asn Phe
         35                  40                  45

Leu Lys Glu Glu Lys Leu Leu Ser Asp Ser Met Leu Val Glu Ala Arg
     50                  55                  60

Glu Ala Ser Glu Glu Asp Leu Leu Val Val His Thr Xaa Arg Tyr Leu
 65                  70                  75                  80

Asn Glu Leu Lys Trp Ser Phe Ala Val Ala Thr Ile Thr Glu Ile Pro
                 85                  90                  95

Pro Val Ile Phe Leu Pro Asn Phe Leu Val Xaa Xaa Xaa Val Leu Arg
            100                 105                 110

Pro Phe Xaa Xaa Xaa Gln Glu Glu Pro 
        115                 120



<210> 1554
<211> 109
<212> PRT
<213> Homo sapiens

<400> 1554
Met Ala Val Asn Pro Glu Ala Glu Val Phe Arg Trp Arg Pro Ser Gly
  1               5                  10                  15

Leu Cys Ser Ser Ser Phe Phe Leu Pro His Ser Ala Phe Phe Leu Pro
             20                  25                  30

Trp Thr Pro Gly Gly Asp Leu Trp Arg Asp Ser Phe Asp Leu Thr Pro
         35                  40                  45

Arg Gly Asp Ser Phe Asp Leu Phe Ser Thr Arg Lys Glu Ala Leu Arg
     50                  55                  60

Met Val Ala Val Arg Lys His Gly Ser Leu Arg Thr Ser Leu Ser Phe
 65                  70                  75                  80

Leu Leu Asp Ile Ile Glu Phe Val Gly Pro Cys Leu Phe Leu Leu Pro
                 85                  90                  95

Val Gly Leu Pro Arg Val Pro Ala Gly Leu Ser Met His 
            100                 105



<210> 1555
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1555
Met Ala Met Ser Val Ser Ala Glu Asp Asp Asp Tyr Glu Ser Glu Pro
  1               5                  10                  15

Asp Gln Asn Arg Ala Val Gly Arg Pro Lys Gly Lys Leu Gly Pro Ala
             20                  25                  30

Ser Ala Val Lys Leu Ala Ala Asn Arg Thr Thr Ala Gly Ala Arg Arg
         35                  40                  45

Arg Arg Thr Arg Cys Arg Lys Cys Glu Ala Cys Leu Arg Thr Glu Cys
     50                  55                  60

Gly Glu Cys His Phe Cys Lys Asp Met Lys Lys Phe Gly Gly Pro Gly
 65                  70                  75                  80

Arg Met Lys Gln Ser Cys Ile Met Arg Gln Cys Ile Ala Pro Val Leu
                 85                  90                  95

Pro His Thr Ala Val Cys Leu Val Cys Cys Glu Ala Gly Lys Glu Asp
            100                 105                 110

Xaa Val Glu Glu Xaa Glu Ser Lys Phe Asn Leu Met Leu Met Glu Xaa
        115                 120                 125

Ser Ile Cys Asn Glu Ser Ser Thr Leu Asp Ala Leu Arg 
    130                 135                 140



<210> 1556
<211> 100
<212> PRT
<213> Homo sapiens

<400> 1556
Met Ala Ala Ala Ala Ala Ala Gly Ser Gly Thr Pro Arg Glu Glu Glu
  1               5                  10                  15

Val Pro Ala Gly Glu Ala Ala Ala Ser Gln Pro Gln Ala Pro Thr Ser
             20                  25                  30

Val Pro Gly Ala Arg Leu Ser Arg Leu Pro Leu Ala Arg Val Lys Ala
         35                  40                  45

Leu Val Lys Ala Asp Pro Asp Val Thr Leu Ala Gly Gln Glu Ala Ile
     50                  55                  60

Phe Ile Leu Ala Arg Ala Ala Glu Leu Phe Val Glu Thr Ile Ala Lys
 65                  70                  75                  80

Asp Ala Tyr Cys Cys Ala Gln Gln Gly Lys Lys Glu Asn Pro Ser Glu
                 85                  90                  95

Glu Arg Leu Gly 
            100



<210> 1557
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1557
Met Leu Pro Cys Ala Arg Gly Tyr Phe Ala Arg Val His Gly Val Ser
  1               5                  10                  15

Gln Leu Ile Lys Ala Phe Leu Arg Lys Thr Glu Cys His Cys Gln Ile
             20                  25                  30

Val Asn Leu Gly Ala Gly Met Asp Thr Thr Phe Trp Arg Leu Lys Asp
         35                  40                  45

Glu Asp Leu Leu Pro Ser Lys Tyr Phe Glu Val Asp Phe Pro Met Ile
     50                  55                  60

Val Thr Arg Lys Leu His Ser Ile Lys Leu Pro Thr Leu Leu Ile Ala
 65                  70                  75                  80

Glu Cys Val Leu Val Tyr Met Xaa Pro Glu Gln Ser Ala Asn Leu Leu
                 85                  90                  95

Lys Trp Ala Ala Asn Ser Phe Glu Arg Ala Met Phe Ile Asn Tyr Glu
            100                 105                 110

Gln Val Asn Met Gly Asp Arg Leu Gly Gln Ile Met Ile Glu Asn Leu
        115                 120                 125

Xaa Arg Arg Gln Cys Asp Leu Ala Gly Val Glu Thr Ala Ser His 
    130                 135                 140



<210> 1558
<211> 120
<212> PRT
<213> Homo sapiens

<400> 1558
Met Thr Gly Trp Asn Pro Val Arg Leu Tyr Glu Gln Leu Leu Gln Lys
  1               5                  10                  15

Glu Glu Glu Leu Pro Asp Glu Arg Trp Met Ser Tyr Glu Glu Arg His
             20                  25                  30

Leu Leu Asp Glu Leu Tyr Ile Thr Lys Arg Arg Leu Lys Glu Ile Glu
         35                  40                  45

Glu Arg Leu His Gly Leu Lys Ala Ser Ser Met Thr Gln Thr Pro Ala
     50                  55                  60

Leu Lys Phe Lys Val Glu Asn Phe Phe Cys Met Gly Ser Pro Leu Ala
 65                  70                  75                  80

Val Phe Leu Ala Leu Arg Gly Ile Arg Pro Gly Asn Thr Gly Ser Gln
                 85                  90                  95

Asp His Ile Leu Pro Arg Glu Ile Cys Asn Arg Leu Leu Asn Ile Phe
            100                 105                 110

His Pro Thr Asp Pro Val Gly Leu 
        115                 120



<210> 1559
<211> 127
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1559
Met Glu Glu Lys Tyr Gly Gly Asp Val Leu Ala Gly Pro Gly Gly Gly
  1               5                  10                  15

Gly Gly Leu Gly Xaa Xaa Asp Val Pro Ser Ala Arg Thr Ala Phe Phe
             20                  25                  30

Met Val Leu Phe Gln Lys Pro Phe Ser Ser Gly Lys Xaa Ile Thr Lys
         35                  40                  45

His Gln Trp Ile Lys Ile Phe Lys His Ala Val Ala Gly Cys Ile Ile
     50                  55                  60

Ser Leu Leu Trp Phe Phe Gly Leu Thr Leu Cys Gly Pro Leu Arg Thr
 65                  70                  75                  80

Leu Leu Leu Phe Glu His Ser Asp Ile Val Val Ile Ser Leu Leu Ser
                 85                  90                  95

Val Leu Phe Thr Ser Ser Gly Gly Gly Pro Ala Lys Thr Arg Gly Ala
            100                 105                 110

Ala Phe Phe Ile Ile Ala Val Ile Cys Leu Leu Leu Phe Xaa Asn 
        115                 120                 125



<210> 1560
<211> 159
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1560
Met Trp Arg Asn Gly Thr Ser Ser Cys Arg Arg Leu Arg Ser Gln Gly
  1               5                  10                  15

Ser Cys His Ile Gly Gly Asn Val Ala Thr Asn Ala Gly Gly Leu Arg
             20                  25                  30

Phe Leu Arg Tyr Gly Ser Leu His Gly Thr Val Leu Gly Leu Glu Val
         35                  40                  45

Val Leu Ala Asp Gly Thr Val Leu Asp Cys Leu Thr Xaa Leu Arg Lys
     50                  55                  60

Asp Asn Thr Gly Tyr Asp Leu Lys Gln Leu Phe Ile Gly Ser Glu Gly
 65                  70                  75                  80

Thr Leu Gly Ile Ile Thr Thr Val Ser Ile Leu Cys Pro Pro Lys Pro
                 85                  90                  95

Arg Ala Val Asn Val Ala Phe Leu Arg His Leu Cys Ala Ala Arg Leu
            100                 105                 110

Trp Ser Trp Glu Pro Xaa Ala Thr Pro Ala Cys Arg Ile Leu Leu Phe
        115                 120                 125

Pro Leu Pro Ser Leu Pro Ser Phe Ala Glu Ser Ser Cys Xaa Thr Phe
    130                 135                 140

His Thr Cys Lys Gly Asn Ala Xaa Xaa Arg Ser Cys Leu Ala Phe 
145                 150                 155



<210> 1561
<211> 186
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1561
Met Asp Ala Ala Glu Gly Trp Leu Trp Thr Val Val Ser Trp Leu Leu
  1               5                  10                  15

Lys Val Met Val Arg Leu Val Asp Val Leu Gly Ala Thr Cys Val Met
             20                  25                  30

Lys Gly Val Xaa Leu Trp Phe Thr Val Ser Tyr Ile Phe Thr Arg Arg
         35                  40                  45

Leu Gln Ile Ser Met Phe Trp Lys His Asp Leu Thr Cys Val Leu Trp
     50                  55                  60

Gly Lys Ser Ser Lys Cys Val Met Val Thr Lys Gly Trp Phe Arg Val
 65                  70                  75                  80

Ser Ile Gly Val Ile Leu Leu Ser Ala Ser Met Val Ser Ile Phe Phe
                 85                  90                  95

Asn Arg Ser Met Asn Ser Arg Arg Ser Ala Phe Ser Thr Asn Met Ser
            100                 105                 110

Leu Pro Ser Lys Ser Val Val Met Phe Thr Trp Ala Ile Ser Ser Lys
        115                 120                 125

Gln Leu Lys Met Tyr Phe Leu Ala Ser Phe Asp Leu Ile Pro Val Ser
    130                 135                 140

Ala Ser Trp Ser Ser Gly Val Phe Ser Leu His Lys Gly Tyr Gly Glu
145                 150                 155                 160

Ser Val Ser Arg Leu Lys Asn Leu Val Val Phe Val Pro Xaa Leu Asn
                165                 170                 175

Lys Tyr Ser Ala Gly Lys Pro Cys Val Xaa 
            180                 185



<210> 1562
<211> 231
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1562
Met Ile Asp Met Leu Tyr Phe Val Val Ile Met Leu Val Val Leu Met
  1               5                  10                  15

Ser Phe Gly Val Ala Arg Gln Ala Ile Leu His Pro Glu Glu Lys Pro
             20                  25                  30

Ser Trp Lys Leu Ala Arg Asn Ile Phe Tyr Met Pro Tyr Trp Met Ile
         35                  40                  45

Tyr Gly Glu Val Phe Ala Asp Gln Ile Asp Leu Tyr Ala Met Glu Ile
     50                  55                  60

Asn Pro Pro Cys Gly Glu Asn Leu Tyr Asp Glu Glu Gly Lys Arg Leu
 65                  70                  75                  80

Pro Pro Cys Ile Pro Gly Ala Trp Leu Thr Pro Ala Leu Met Ala Cys
                 85                  90                  95

Tyr Leu Leu Val Ala Asn Ile Leu Leu Val Asn Leu Leu Ile Ala Val
            100                 105                 110

Phe Asn Asn Thr Phe Phe Glu Val Lys Ser Ile Ser Asn Gln Val Trp
        115                 120                 125

Lys Phe Gln Arg Tyr Gln Leu Ile Met Thr Phe His Asp Arg Pro Val
    130                 135                 140

Leu Pro Pro Pro Met Ile Ile Leu Ser His Ile Tyr Ile Ile Ile Met
145                 150                 155                 160

Arg Leu Ser Gly Arg Cys Arg Lys Lys Arg Glu Gly Asp Gln Glu Glu
                165                 170                 175

Arg Asp Arg Gly Leu Lys Leu Phe Leu Ser Asp Glu Glu Leu Lys Arg
            180                 185                 190

Leu His Glu Phe Glu Glu Gln Cys Val Gln Glu Xaa Ser Gly Arg Arg
        195                 200                 205

Arg Met Ser Ser Ser Arg Pro Ala Thr Ser Ala Ser Gly Ser Leu Leu
    210                 215                 220

Lys Glu Leu Lys Ile Cys Gln 
225                 230



<210> 1563
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1563
Met Asn Ser Gly Gly Gly Phe Gly Leu Gly Leu Gly Phe Gly Leu Thr
  1               5                  10                  15

Pro Thr Ser Val Ile Gln Val Thr Asn Leu Ser Ser Ala Val Thr Ser
             20                  25                  30

Glu Gln Met Arg Thr Leu Phe Ser Phe Leu Gly Glu Ile Glu Glu Leu
         35                  40                  45

Arg Leu Tyr Pro Pro Asp Asn Ala Pro Leu Ala Phe Ser Ser Lys Val
     50                  55                  60

Cys Tyr Val Lys Phe Arg Asp Pro Ser Ser Val Gly Val Ala Gln His
 65                  70                  75                  80

Leu Thr Asn Thr Val Phe Ile Asp Arg Ala Leu Ile Val Val Pro Cys
                 85                  90                  95

Ala Glu Gly Trp Ile Ser Leu Phe Phe Xaa Leu Leu Asn Ser Val Leu
            100                 105                 110

Ser Val Met Pro 
        115



<210> 1564
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1564
Met Thr Gln Glu Ser Arg Ala Cys Ser Ser Val Trp Lys Glu Phe Gly
  1               5                  10                  15

Ser Val Gly Arg Cys Asn Val His Arg His Phe Gln Gly Asn Ser Lys
             20                  25                  30

Gln Ser Pro Phe Pro Phe Ala Phe Pro Gln Ile Leu Ser Val Tyr Ile
         35                  40                  45

Lys Pro Trp Val His Ile Val Val Val Ile Glu Gly Asn Trp Leu Asn
     50                  55                  60

Ser Thr Leu Val Tyr Gly Thr Phe Cys Gly His Leu Arg Lys Thr Ser
 65                  70                  75                  80

Tyr Xaa Leu Xaa Gly Gly Xaa Cys Cys Pro Ala Arg Gly Arg Xaa Ile
                 85                  90                  95

Leu Thr Thr Xaa Pro Pro Trp Pro Leu Ser Thr Phe His Gly Gly His
            100                 105                 110

Ala Xaa His 
        115



<210> 1565
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1565
Met Glu Glu Leu Leu Leu Leu Ala Lys Glu Ser Ser Arg Ser Asn His
  1               5                  10                  15

Thr Ile Trp Phe Gly His Phe Thr Thr Ser Thr Ile Leu Ser Pro Ser
             20                  25                  30

Pro Gly Ile Arg Ser Ile Met Ser Ser Ala Ile Ala Tyr Leu Cys Gly
         35                  40                  45

His Leu His Thr Leu Gly Gly Leu Met Pro Val Leu His Thr Arg His
     50                  55                  60

Phe Gln Gly Thr Leu Glu Leu Glu Val Gly Asp Trp Lys Asp Asn Arg
 65                  70                  75                  80

Arg Tyr Arg Ile Phe Ala Phe Asp His Asp Leu Phe Ser Phe Ala Asp
                 85                  90                  95

Leu Ile Phe Gly Lys Trp Pro Val Val Leu Ile Thr Asn Pro Lys Ser
            100                 105                 110

Leu Leu Tyr Ser Cys Gly Glu His Glu Pro Leu Arg Lys Thr Ser Ser
        115                 120                 125

Xaa Gln His Thr Ser Glu Ser Trp Xaa 
    130                 135



<210> 1566
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1566
Met Thr Ser Asn Gln Ser Ser Thr Leu Tyr Val Thr Asp Gln Gly Gly
  1               5                  10                  15

Val Tyr Phe Glu Val His Thr Pro Gly Val Tyr Arg Asp Leu Phe Gly
             20                  25                  30

Thr Leu Gln Ala Phe Asp Pro Leu Asp Gln Gln Met Pro Leu Ala Leu
         35                  40                  45

Xaa Leu Pro Ala Lys Ile Leu Phe Cys Ala Leu Gly Tyr Asn His Leu
     50                  55                  60

Gly Leu Val Asp Glu Phe Gly Arg Ile Phe Met Gln Gly Asn Asn Arg
 65                  70                  75                  80

Tyr Gly Gln Leu Gly Thr Gly Asp Lys Xaa Asp Arg Gly Gly Thr His
                 85                  90                  95

Thr Gly Leu Phe Xaa Cys Ser Gly Xaa Ile Thr Leu Trp Val Arg Gly
            100                 105                 110

Leu Gln Thr Asn Ser Leu Val Ala 
        115                 120



<210> 1567
<211> 254
<212> PRT
<213> Homo sapiens

<400> 1567
Met Gly Ser Gly Cys Arg Ile Glu Cys Ile Phe Phe Ser Glu Phe His
  1               5                  10                  15

Pro Thr Leu Gly Pro Lys Ile Thr Tyr Gln Val Pro Glu Asp Phe Ile
             20                  25                  30

Ser Arg Glu Leu Phe Asp Thr Val Gln Val Tyr Ile Ile Thr Lys Pro
         35                  40                  45

Glu Leu Gln Asn Lys Leu Ile Thr Val Thr Ala Met Glu Lys Lys Leu
     50                  55                  60

Ile Gly Cys Pro Val Cys Ile Glu His Lys Lys Tyr Ser Arg Asn Ala
 65                  70                  75                  80

Leu Leu Phe Asn Leu Gly Phe Val Cys Asp Ala Gln Ala Lys Thr Cys
                 85                  90                  95

Ala Leu Glu Pro Ile Val Lys Lys Leu Ala Gly Tyr Leu Thr Thr Leu
            100                 105                 110

Glu Leu Glu Ser Ser Phe Val Ser Met Glu Glu Ser Lys Gln Lys Leu
        115                 120                 125

Val Pro Ile Met Thr Ile Leu Leu Glu Glu Leu Asn Ala Ser Gly Arg
    130                 135                 140

Cys Thr Leu Pro Ile Asp Glu Ser Asn Thr Ile His Leu Lys Val Ile
145                 150                 155                 160

Glu Gln Arg Pro Asp Pro Pro Val Ala Gln Glu Tyr Asp Val Pro Val
                165                 170                 175

Phe Thr Lys Asp Lys Glu Asp Phe Phe Asn Ser Gln Trp Asp Leu Thr
            180                 185                 190

Thr Gln Gln Ile Leu Pro Tyr Ile Asp Gly Phe Arg His Ile Gln Lys
        195                 200                 205

Ile Ser Ala Glu Ala Asp Val Glu Leu Asn Leu Val Arg Ile Ala Ile
    210                 215                 220

Gln Asn Leu Leu Tyr Tyr Gly Val Val Thr Leu Val Ser Ile Leu Gln
225                 230                 235                 240

Tyr Ser Asn Val Tyr Cys Pro Thr Pro Lys Val Gln Asp Trp 
                245                 250



<210> 1568
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1568
Met Asp Gly Gln Lys Lys Asn Trp Lys Asp Lys Val Val Asp Leu Leu
  1               5                  10                  15

Tyr Trp Arg Asp Ile Lys Lys Thr Gly Val Val Phe Gly Ala Ser Leu
             20                  25                  30

Phe Leu Leu Leu Ser Leu Thr Val Phe Ser Ile Val Ser Val Thr Ala
         35                  40                  45

Tyr Ile Ala Leu Ala Leu Leu Ser Val Thr Ile Ser Phe Arg Ile Tyr
     50                  55                  60

Lys Gly Val Ile Gln Ala Ile Gln Lys Ser Asp Glu Gly His Pro Phe
 65                  70                  75                  80

Arg Ala Tyr Leu Glu Ser Glu Val Ala Ile Ser Glu Glu Leu Val Gln
                 85                  90                  95

Lys Tyr Ser Asn Ser Ala Leu Gly His Val Asn Cys Thr Ile Lys Gly
            100                 105                 110

Thr Gln Ala Pro Leu Xaa 
        115



<210> 1569
<211> 131
<212> PRT
<213> Homo sapiens

<400> 1569
Met Gly Glu Pro Gly Glu Gly Gly Leu Gly Ala Trp Gly Arg Lys Ala
  1               5                  10                  15

Gly Arg Ser Pro Ser Trp Val Val Leu Ala Gln Leu Val Gly Pro Leu
             20                  25                  30

Ser Thr Pro Thr Leu Phe Ile Ser Val Val Ser Leu Leu Cys Arg Pro
         35                  40                  45

Thr Leu Pro Arg Val Leu Leu Pro Pro Ala Pro Ala Ser His Leu Leu
     50                  55                  60

Leu Thr Ala Ser Ser Cys Val Phe Asp Lys Val Ile Gly Ile Phe Leu
 65                  70                  75                  80

Leu Thr Gly Phe Ser Leu His Phe Thr Cys Ser Phe Pro Glu Leu Thr
                 85                  90                  95

Ala Arg Ala Pro Ala Gln Cys Ala Trp Leu Gly Phe Pro Ser Pro Trp
            100                 105                 110

Leu Gly Ala Gly Val Gly Leu Thr His Ser Asn Leu Phe Cys Leu Leu
        115                 120                 125

Ala Ser Gln 
    130



<210> 1570
<211> 146
<212> PRT
<213> Homo sapiens

<400> 1570
Met Val Asp Leu Arg Gly Leu Val His Ala Ala Gly Pro Gly Gln Asp
  1               5                  10                  15

Ser Gly Ser Gln Ala Gly Ser Pro Pro Thr Arg Asp Arg Asp Val Asp
             20                  25                  30

Val Leu Ser Ala Ala Leu Lys Glu Gln Leu Ser His Ser Arg Gln Val
         35                  40                  45

His Ser Cys Leu Glu Gly Leu Arg Glu Gln Leu Asp Gly Leu Glu Lys
     50                  55                  60

Thr Cys Ser Gln Met Ala Gly Val Val Gln Leu Val Lys Ser Ala Ala
 65                  70                  75                  80

His Pro Gly Leu Val Glu Pro Ala Asp Gly Ala Met Pro Ser Phe Leu
                 85                  90                  95

Leu Glu Gln Gly Ser Met Ile Leu Ala Leu Ser Asp Thr Glu Gln Arg
            100                 105                 110

Leu Glu Ala Gln Val Asn Arg Asn Thr Ile Tyr Ser Thr Leu Val Thr
        115                 120                 125

Cys Val Thr Phe Val Ala Thr Leu Pro Val Leu Tyr Met Leu Phe Lys
    130                 135                 140

Ala Ser 
145



<210> 1571
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1571
Met Asp Leu Cys Cys Ser Arg Ile Lys Arg Thr Asn Phe Tyr Leu Asn
  1               5                  10                  15

Tyr Ser Leu Phe Tyr Val Tyr Ile Leu Ala Ser Glu Val Lys Tyr Tyr
             20                  25                  30

Leu Ser His Met Cys Phe Ile Leu Phe Asp Phe His Ile Asn Leu Phe
         35                  40                  45

Ile Val Leu Leu Asp Ile Ser Ser Cys Leu Arg Ile Ile Thr Glu Ser
     50                  55                  60

Gln Trp Ala Cys Lys Phe Xaa Leu Thr Lys Ile Phe Leu Thr Val His
 65                  70                  75                  80

Tyr Ser Pro Asn Ser Ile Tyr Ala Thr Ile Val Leu Ile Lys Glu Val
                 85                  90                  95

Leu Leu Leu Phe Leu Arg Lys Ile His Lys Leu Gln Asn Ile Ile 
            100                 105                 110



<210> 1572
<211> 244
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (213)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1572
Met Ala Met Asn Tyr Asn Ala Lys Asp Glu Val Asp Gly Gly Pro Pro
  1               5                  10                  15

Cys Ala Pro Gly Gly Thr Ala Lys Thr Arg Arg Pro Asp Asn Thr Ala
             20                  25                  30

Phe Lys Gln Gln Arg Leu Pro Ala Trp Gln Pro Ile Leu Thr Ala Gly
         35                  40                  45

Thr Val Leu Pro Ile Phe Phe Ile Ile Gly Leu Ile Phe Ile Pro Ile
     50                  55                  60

Gly Ile Gly Ile Phe Val Thr Ser Asn Asn Ile Arg Glu Ile Glu Ile
 65                  70                  75                  80

Asp Tyr Thr Gly Thr Glu Pro Ser Ser Pro Cys Asn Lys Cys Leu Ser
                 85                  90                  95

Pro Asp Val Thr Pro Cys Phe Cys Thr Ile Asn Phe Thr Leu Glu Lys
            100                 105                 110

Ser Phe Glu Gly Asn Val Phe Met Tyr Tyr Gly Leu Ser Asn Phe Tyr
        115                 120                 125

Gln Asn His Arg Arg Tyr Val Lys Ser Arg Asp Asp Ser Gln Leu Asn
    130                 135                 140

Gly Asp Ser Ser Ala Leu Leu Asn Pro Ser Lys Glu Cys Glu Pro Tyr
145                 150                 155                 160

Arg Arg Asn Glu Asp Lys Pro Ile Ala Pro Cys Gly Ala Ile Ala Asn
                165                 170                 175

Ser Met Phe Asn Asp Thr Leu Glu Leu Phe Leu Ile Gly Asn Asp Ser
            180                 185                 190

Tyr Pro Ile Pro Ile Ala Leu Lys Lys Lys Gly Ile Ala Trp Trp Thr
        195                 200                 205

Xaa Lys Asn Val Xaa Phe Arg Asn Pro Pro Gly Gly Asp Asn Leu Glu
    210                 215                 220

Glu Arg Phe Lys Gly Thr Thr Lys Pro Val Asn Trp Leu Lys Pro Val
225                 230                 235                 240

Tyr Met Leu Asp 




<210> 1573
<211> 186
<212> PRT
<213> Homo sapiens

<400> 1573
Met Leu Leu Leu Glu Thr Leu Lys Val Lys Gln Thr Ile Leu Glu Pro
  1               5                  10                  15

Ile Pro Thr Ser Leu Lys Leu Pro Ile Ala Val Ser Cys Tyr Trp Leu
             20                  25                  30

Gln His Thr Glu Thr Lys Ala Lys Leu His His Leu Gln Ser Leu Leu
         35                  40                  45

Leu Thr Met Leu Val Gly Pro Leu Ile Ala Ile Ile Asn Ser Pro Gly
     50                  55                  60

Lys Glu Glu Leu Gln Glu Asp Gly Ala Lys Met Leu Tyr Ala Glu Phe
 65                  70                  75                  80

Gln Arg Val Lys Ala Gln Thr Arg Leu Gly Thr Arg Leu Asp Leu Asp
                 85                  90                  95

Thr Ala His Ile Phe Cys Gln Trp Gln Ser Cys Leu Gln Met Gly Met
            100                 105                 110

Tyr Leu Asn Gln Leu Leu Ser Thr Pro Leu Pro Glu Pro Asp Leu Thr
        115                 120                 125

Arg Leu Tyr Ser Gly Ser Leu Val His Gly Leu Cys Gln Gln Leu Leu
    130                 135                 140

Ala Ser Thr Ser Val Glu Ser Leu Leu Ser Ile Cys Pro Glu Ala Lys
145                 150                 155                 160

Gln Leu Tyr Glu Tyr Leu Phe Asn Ala Thr Arg Ser Tyr Ala Pro Ala
                165                 170                 175

Glu Ile Phe Leu Pro Lys Gly Arg Ser Asn 
            180                 185



<210> 1574
<211> 272
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1574
Met Arg Leu Ser Phe Ile Val Phe Ser Ser Gln Ala Thr Ile Ile Leu
  1               5                  10                  15

Pro Leu Thr Gly Asp Arg Gly Lys Ile Ser Lys Gly Leu Glu Asp Leu
             20                  25                  30

Lys Arg Val Ser Pro Val Gly Glu Thr Tyr Ile His Glu Gly Leu Lys
         35                  40                  45

Leu Ala Asn Glu Gln Ile Gln Lys Ala Gly Gly Leu Lys Thr Ser Ser
     50                  55                  60

Ile Ile Ile Ala Leu Thr Asp Gly Lys Leu Asp Gly Leu Val Pro Ser
 65                  70                  75                  80

Tyr Ala Glu Lys Glu Ala Lys Ile Ser Arg Ser Leu Gly Ala Ser Val
                 85                  90                  95

Tyr Cys Val Gly Val Leu Asp Phe Glu Gln Ala Gln Leu Glu Arg Ile
            100                 105                 110

Ala Asp Ser Lys Glu Gln Val Phe Pro Val Lys Gly Gly Phe Gln Ala
        115                 120                 125

Leu Lys Gly Ile Ile Asn Ser Ile Leu Ala Gln Ser Cys Thr Glu Ile
    130                 135                 140

Leu Glu Leu Gln Pro Ser Ser Val Cys Val Gly Glu Glu Phe Gln Ile
145                 150                 155                 160

Val Leu Ser Gly Arg Gly Phe Met Leu Gly Ser Arg Asn Gly Ser Val
                165                 170                 175

Leu Cys Thr Tyr Thr Val Asn Glu Thr Tyr Thr Thr Ser Val Lys Pro
            180                 185                 190

Val Ser Val Gln Leu Asn Ser Met Leu Cys Pro Ala Pro Ile Leu Asn
        195                 200                 205

Lys Ala Gly Glu Thr Leu Asp Val Ser Val Ser Phe Asn Gly Gly Lys
    210                 215                 220

Ser Val Ile Ser Gly Ser Leu Ile Val Thr Ala Xaa Xaa Cys Ser Asn
225                 230                 235                 240

Gly Ile Ala Ala Ile Ile Val Ile Leu Val Leu Leu Leu Leu Leu Gly
                245                 250                 255

Ile Gly Leu Met Trp Trp Phe Trp Thr Pro Leu Leu Gln Ser Gly Tyr
            260                 265                 270






<210> 1575
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1575
Met Leu His Ser Ser Leu Cys Leu Arg Gly His Met Val Ser Ser Pro
  1               5                  10                  15

Cys Xaa Pro Ala Ala Ser Cys Gly Leu Leu Ile Arg Thr Pro Val Thr
             20                  25                  30

Gly Phe Arg Thr His Pro Lys Ser Arg Arg Thr Ser Ser Met Arg Met
         35                  40                  45

Ala Tyr Thr Lys Ser Leu Phe Pro Asn Glu Val His Ile Leu Arg Phe
     50                  55                  60

Trp Val Gly Gln Val Phe Val Lys Thr Leu Phe Ser Leu Val His Xaa
 65                  70                  75                  80

His Ser Ser Thr Ser Lys Met Glu Phe Pro Lys Leu Leu Ile Ala Ile
                 85                  90                  95

Phe Ile Thr Ala Asp Phe Ile Thr Leu Thr Lys Lys Lys Lys Lys Gly
            100                 105                 110

Gly Pro Leu Lys Gly 
        115



<210> 1576
<211> 121
<212> PRT
<213> Homo sapiens

<400> 1576
Met Ile Val Val Thr Pro Ala Gly Leu His Leu Asn Trp Ile His Arg
  1               5                  10                  15

Glu Ala Phe His Gly His Ile Met Asn Arg Glu Asn Arg Tyr Phe Gln
             20                  25                  30

Lys Asn Gln Pro Ile Val Phe Ser Arg Asn Arg Thr Glu Asn Val Gln
         35                  40                  45

Asn Ile Phe Lys Phe Val Arg Phe Phe Tyr Val Ser Phe Glu Ile Tyr
     50                  55                  60

Tyr Leu Ser Leu Leu Leu Asn Leu Tyr Lys Asn Ile Phe Gly Lys Tyr
 65                  70                  75                  80

Thr Lys Glu Thr Ser Leu Gln Lys Ile Met Ile Ile Asn Glu Leu Gln
                 85                  90                  95

Thr Ser Ser Phe Glu Asn Lys Val Leu Cys Phe Phe Phe Phe Val Asn
            100                 105                 110

Ile Cys Val Tyr Lys Cys Thr Ala Glu 
        115                 120



<210> 1577
<211> 109
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1577
Met Leu Ile Met Leu Gly Ile Phe Phe Asn Val His Ser Ala Val Leu
  1               5                  10                  15

Ile Glu Asp Val Pro Phe Thr Glu Lys Asp Phe Glu Asn Gly Pro Gln
             20                  25                  30

Asn Ile Tyr Asn Leu Tyr Glu Gln Val Ser Tyr Asn Cys Phe Ile Ala
         35                  40                  45

Ala Gly Leu Tyr Leu Leu Leu Gly Gly Phe Ser Phe Cys Gln Phe Gly
     50                  55                  60

Ser Ile Ser Ala Arg Asn Asn Met Gly Ser Gly Glu Ile Phe Ser Ala
 65                  70                  75                  80

Ala Gly Ala Leu Ser Arg Xaa Arg Gly Ala Thr Met Gln Cys Ile Pro
                 85                  90                  95

Trp Pro Ile Leu Ser Ala Gly Ala Asn Gly Arg Arg Gly 
            100                 105



<210> 1578
<211> 216
<212> PRT
<213> Homo sapiens

<400> 1578
Met Thr Val Met Ser Leu Leu Val Leu Val Leu Ser Trp Gly Ser Met
  1               5                  10                  15

Gly Leu Glu Ala Ala Thr Ala Val Gly Leu Ser Asp Phe Cys Ser Asn
             20                  25                  30

Pro Asp Pro Tyr Val Leu Asn Leu Thr Gln Glu Glu Thr Gly Leu Ser
         35                  40                  45

Ser Asp Ile Leu Ser Tyr Tyr Leu Leu Cys Asn Arg Ala Val Ser Asn
     50                  55                  60

Pro Phe Gln Gln Arg Leu Thr Leu Ser Gln Arg Ala Leu Ala Asn Ile
 65                  70                  75                  80

His Ser Gln Leu Leu Gly Leu Glu Arg Glu Ala Val Pro Gln Phe Pro
                 85                  90                  95

Ser Ala Gln Lys Pro Leu Leu Ser Leu Glu Glu Thr Leu Asn Val Asp
            100                 105                 110

Arg Lys Glu Ile Ser Thr Ser Trp Trp His Cys Tyr Thr Ala Ala Ala
        115                 120                 125

Leu His Lys Asp Tyr Gly Ala Ala Leu Arg Gly Leu Cys Glu Tyr Ala
    130                 135                 140

Leu Glu Gly Leu Leu Phe Leu Leu Leu Phe Ser Leu Leu Ser Ala Gly
145                 150                 155                 160

Ala Leu Ala Thr Ala Leu Cys Ser Leu Pro Arg Ala Trp Ala Leu Phe
                165                 170                 175

Pro Pro Arg Asn Pro Ser Ala Leu Cys Ser Gly Ser Arg Leu Ser Glu
            180                 185                 190

Pro Leu Leu Pro Ala Gly Leu Glu Pro Gly Ser Pro Leu Arg Ser Phe
        195                 200                 205

Pro Gly Cys Arg Arg Arg Pro His 
    210                 215



<210> 1579
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1579
Met Glu Ile Asn Thr Lys Leu Leu Ile Ser Val Thr Cys Ile Ser Phe
  1               5                  10                  15

Phe Thr Phe Gln Leu Leu Phe Tyr Phe Val Ser Tyr Trp Phe Ser Ala
             20                  25                  30

Lys Val Ser Pro Gly Phe Asn Ser Leu Ser Phe Lys Lys Lys Ile Glu
         35                  40                  45

Trp Asn Ser Arg Val Val Ser Thr Cys His Ser Leu Val Val Gly Ile
     50                  55                  60

Phe Gly Leu Xaa Ile Phe Leu Xaa Asp Glu Ala Thr Xaa Ala Asp Pro
 65                  70                  75                  80

Leu Xaa Gly Gly Pro Ser Leu Ala Asn Val Asn Ile Ala Ile Ala Ser
                 85                  90                  95

Gly Tyr Leu Ile Ser Asp Leu Ser Ile Ile Ile Leu Tyr Xaa Lys Val
            100                 105                 110

Ile Gly Asp Lys Phe Phe Ile Xaa His His Cys Ala Xaa Leu Xaa Ala
        115                 120                 125

Tyr Xaa Xaa Xaa Leu Ile Leu Val Asn Lys Ser Leu Ile Trp His Asn
    130                 135                 140

Phe Phe Lys Ile Arg Tyr Ile Glu Thr Ser Leu Gln Thr Thr His Leu
145                 150                 155                 160

Asp His Xaa Ile Asn Asn Xaa Lys Arg Xaa 
                165                 170



<210> 1580
<211> 134
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1580
Met Gln Ala His Gln Glu Lys Leu Gln Leu Glu Gln Leu Arg Leu Glu
  1               5                  10                  15

Glu Glu Val Ala Arg Leu Ala Ala Glu Lys Glu Ala Leu Glu Gln Val
             20                  25                  30

Ala Glu Glu Gly Arg Gln Gln Asn Glu Thr Arg Val Ala Trp Asp Leu
         35                  40                  45

Trp Ser Thr Leu Cys Met Ile Leu Phe Leu Met Ile Glu Val Trp Arg
     50                  55                  60

Gln Asp His Gln Glu Gly Pro Ser Pro Glu Cys Leu Gly Gly Glu Glu
 65                  70                  75                  80

Asp Glu Leu Pro Gly Leu Gly Gly Ala Pro Leu Gln Gly Leu Thr Leu
                 85                  90                  95

Pro Asn Lys Ala Thr Leu Gly His Phe Tyr Glu Arg Cys Ile Arg Gly
            100                 105                 110

Ala Thr Ala Asp Ala Ala Arg Thr Arg Xaa Phe Leu Glu Xaa Phe Val
        115                 120                 125

Asp Asp Cys Trp Lys Pro 
    130



<210> 1581
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1581
Met Ala Gln Arg Ala Phe Pro Asn Pro Tyr Ala Asp Tyr Asn Lys Ser
  1               5                  10                  15

Leu Ala Glu Gly Xaa Phe Asp Ala Ala Gly Arg Leu Thr Pro Glu Phe
             20                  25                  30

Ser Gln Arg Leu Thr Asn Lys Ile Arg Glu Leu Leu Gln Gln Met Glu
         35                  40                  45

Arg Gly Leu Lys Ser Ala Asp Pro Arg Asp Gly Thr Gly Tyr Thr Gly
     50                  55                  60

Trp Ala Gly Ile Ala Val Leu Tyr Leu His Leu Tyr Asp Val Phe Gly
 65                  70                  75                  80

Asp Pro Ala Tyr Leu Gln Leu Ala His Gly Tyr Val Lys Gln Ser Leu
                 85                  90                  95

Asn Cys Leu Thr Lys Arg Ser Ile Thr Phe Leu Cys Gly Asp Ala Gly
            100                 105                 110

Pro Leu Ala Val Ala Ala Val Leu Tyr His Lys Met Asn Asn Glu Lys
        115                 120                 125

Gln Ala Glu Asp Cys Ile Thr Arg Xaa Ile His Leu Lys 
    130                 135                 140



<210> 1582
<211> 139
<212> PRT
<213> Homo sapiens

<400> 1582
Met Gln Arg Cys Thr Pro Leu Phe Asp Gln Ala Ser Ala Pro Leu Ala
  1               5                  10                  15

Tyr His Pro Val Leu Thr Ser Val Thr Val Arg Ala Pro Pro Val Ser
             20                  25                  30

Ala Asp Leu Phe Val Leu Trp Gly Asn Ser Leu Leu Ser Ser Leu Cys
         35                  40                  45

Gln Ser Gln Ala Trp Trp Ile Cys Ile Ser Arg Pro Leu His Thr Val
     50                  55                  60

Pro Leu His Leu Pro Phe Pro Pro Arg Pro Pro Val Gly Gly Ala Gly
 65                  70                  75                  80

Val Ala Ser Val Arg Asn Ser Leu Leu Val Thr Ala Gly Leu Pro Arg
                 85                  90                  95

Val Leu Leu Val Thr Ile Ala Ser Trp Ser Ser Asp Ile Ile Ala Arg
            100                 105                 110

Asn Gly Ala Leu Phe Arg Leu Val Val Trp Pro Ser Gly Phe Leu Thr
        115                 120                 125

Arg Tyr Cys Val Thr Pro Ser Lys Lys Gly Leu 
    130                 135



<210> 1583
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1583
Met Ser Phe Ile Ala Arg His Glu Ala Ser Val Ile Cys Val Leu Arg
  1               5                  10                  15

Asn Arg Arg Ala Ser Leu Ser Gln Glu Ser Glu Val Cys Xaa Ala Ser
             20                  25                  30

Gln Pro Glu Lys Gly Arg Gly Ala His Leu Ala Gly Arg Pro Leu Gly
         35                  40                  45

Arg Gly Val Thr Gly Val Leu Asp Phe Leu Ile Arg Val Ile Val Ala
     50                  55                  60

Gly Pro Leu Gly Arg Arg Leu Leu Leu His Leu Leu Leu Leu Pro Pro
 65                  70                  75                  80

Leu Xaa Leu Ala Lys Glu Leu Leu Ser Phe Gln His Asp Pro Gly Val
                 85                  90                  95

Glu Ala Met Ser Ser Gln 
            100



<210> 1584
<211> 216
<212> PRT
<213> Homo sapiens

<400> 1584
Met Ala Met Lys Pro Ala Lys Lys Ile Thr Lys Thr Phe Leu His Pro
  1               5                  10                  15

Asn Ser Met Thr Asn Leu Lys Ser Leu Lys Arg Thr Arg Lys Thr Lys
             20                  25                  30

Asn Leu Ser Ser Leu Ser Thr Ala Ala Leu Ser Leu Trp Arg Leu Leu
         35                  40                  45

Ser Gln Met Asp Arg Gly Met Ile Val Ser Met Arg Ser Cys Gln Thr
     50                  55                  60

Ala Gln Ala Trp Gly Asp Thr Gly Pro Leu Met Val Gly Pro Ala Val
 65                  70                  75                  80

Leu Thr Trp Gln Gly Ile Thr Asn Leu Val Pro His Cys Leu Leu Phe
                 85                  90                  95

Ser Phe Ile Pro Ser His Gln Leu Gln Glu Lys Asn Thr Arg Pro Tyr
            100                 105                 110

Lys Ile Tyr His Gln Pro Thr His Leu Trp Glu Gln Glu Thr Thr Phe
        115                 120                 125

Gln Leu Asp Gln Ile Thr Ala Leu Ser Thr Ala Val Lys Pro Ile Thr
    130                 135                 140

Ser Thr Ala Asn Arg Cys Val Tyr Ile His Thr Leu Leu Cys Leu Ala
145                 150                 155                 160

Glu Phe His Ser Asn Met Met Leu His Tyr Ala Pro Tyr Cys Asp Asp
                165                 170                 175

Leu Ser Thr Pro Lys Pro Ala Gly Ala Cys Pro Trp Pro Trp Gly Val
            180                 185                 190

Ser Gln Ser Leu Leu Val Pro Leu Val Val His Phe Ile Phe Glu Ser
        195                 200                 205

Phe Ser Phe Ser Tyr Thr Glu Lys 
    210                 215



<210> 1585
<211> 213
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (46)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1585
Met Met Arg Ser Cys Pro Ala Thr Pro Leu Thr Ser Ser Thr Gly Cys
  1               5                  10                  15

Pro Arg Glu His Met Cys Val Leu Val Tyr Leu Val Thr Val Met His
             20                  25                  30

Ser Met Gln Ala Gly Tyr Leu Glu Lys Ala Gln Lys Tyr Xaa Asp Lys
         35                  40                  45

Ala Leu Met Gln Leu Xaa Lys Leu Lys Met Leu Asp Cys Ser Pro Ile
     50                  55                  60

Leu Ser Ser Phe Gln Val Ile Leu Leu Glu His Ile Ile Met Cys Arg
 65                  70                  75                  80

Leu Val Thr Gly His Lys Ala Thr Ala Leu Gln Glu Ile Ser Gln Val
                 85                  90                  95

Cys Gln Leu Cys Gln Gln Ser Pro Arg Xaa Phe Ser Asn His Ala Ala
            100                 105                 110

Gln Leu His Thr Leu Leu Gly Leu Tyr Cys Val Ser Val Asn Cys Met
        115                 120                 125

Asp Asn Ala Glu Pro Ser Ser Pro Arg Pro Cys Gly Ser Pro Thr Thr
    130                 135                 140

Arg Ser Cys Gly Pro Ser Ser Ser Pro Thr Trp Arg Val Cys Ile Tyr
145                 150                 155                 160

Gly Lys Glu Ile Asp Thr Lys Arg Tyr Ser Thr Val Cys Trp Arg Gly
                165                 170                 175

Ser Thr Arg Thr Thr Ala Ser Leu Ser Ala Arg Leu Xaa Arg Gln Pro
            180                 185                 190

Leu Leu Cys Ala Trp Leu Phe Ser Leu Gln Gly Arg Gln Arg Gly Lys
        195                 200                 205

Xaa Ser Ala Glu Thr 
    210



<210> 1586
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1586
Met Tyr Arg Thr Leu Cys Cys Val Gln Trp Arg Asn Leu Pro Gly Pro
  1               5                  10                  15

Gly Glu Ser Ser Asp Ser Ala Ser Arg Leu Cys Phe Ala Ser Ser Asn
             20                  25                  30

Val Glu Leu Thr Ser Gly Pro Gln Ser Pro Ala Gly Xaa Ser Val Arg
         35                  40                  45

His Ala Arg Val Val Glu Met Gly Pro Pro Gly Pro Pro Ala Val His
     50                  55                  60

Trp Ala Glu Thr Ser Gly Lys Pro Ala Ala Gly Ala Leu Pro Gly Gln
 65                  70                  75                  80

Leu Pro Pro Ala Gln Cys Ser Gln Thr Ser Pro Ser Gly Lys Gln Ser
                 85                  90                  95

Val Gln Gln Met Leu Cys Glu Ile Leu Gly Phe Ser Leu Phe Leu Phe
            100                 105                 110

Cys Phe Val Phe Glu Arg Lys Lys Lys Ile Gln Leu Thr Ser Leu Phe
        115                 120                 125

Cys Lys Trp Val Ser Phe Leu Cys Ile Lys Ser Trp Trp Ser Leu Val
    130                 135                 140

Phe Thr Cys Ser Cys Cys Val Ile Leu Arg Cys Tyr 
145                 150                 155



<210> 1587
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1587
Met Leu Tyr Thr Ile Tyr Leu Ala Gln Gln Ile Ile Ala Leu Ile Glu
  1               5                  10                  15

Phe Lys Ser Ala Leu Phe Ser Ser Thr Val Ala Xaa His Ala Trp Gly
             20                  25                  30

Leu Arg Leu Phe Gly Arg Phe Gln Pro Asp Ser Ser Val Pro Leu Leu
         35                  40                  45

Pro Ser Leu Pro Leu Pro Ala Leu Arg Ser Pro Leu Gly Leu Glu Ser
     50                  55                  60

Asp Leu Gly Trp Gly Arg Gly Arg Gly Phe Leu Gly Val Ser Ser Ser
 65                  70                  75                  80

Ala Val Ser Val Pro Leu Ala Phe Arg Phe Phe Leu Pro Phe Leu Leu
                 85                  90                  95

Gly Met Gly Leu Leu Ala Xaa Gly Gly 
            100                 105



<210> 1588
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (169)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1588
Met Leu Tyr Pro Glu Tyr His Lys Val His Gln Met Met Arg Glu Gln
  1               5                  10                  15

Ser Ile Leu Ser Pro Ser Pro Tyr Glu Gly Tyr Arg Ser Leu Pro Arg
             20                  25                  30

His Gln Leu Leu Cys Phe Lys Glu Asp Cys Gln Ala Val Phe Gln Asp
         35                  40                  45

Leu Glu Gly Val Glu Lys Val Phe Gly Val Ser Leu Val Leu Val Leu
     50                  55                  60

Ile Gly Ser His Pro Asp Leu Ser Phe Leu Pro Gly Ala Gly Ala Asp
 65                  70                  75                  80

Phe Ala Val Asp Pro Asp Gln Pro Leu Ser Ala Lys Arg Asn Pro Ile
                 85                  90                  95

Asp Val Asp Pro Phe Thr Tyr Gln Ser Thr Arg Gln Xaa Gly Leu Tyr
            100                 105                 110

Ala Met Gly Pro Leu Ala Gly Asp Asn Phe Val Arg Phe Val Gln Gly
        115                 120                 125

Gly Ala Leu Ala Val Ala Ser Ser Leu Leu Arg Lys Glu Gln Asn His
    130                 135                 140

Leu His Arg Gln Pro Trp Ser Ser Leu Arg Gly Ile His Pro Leu Ile
145                 150                 155                 160

Asp Leu Lys Ser Gly Val Xaa Pro Xaa Leu Val Lys Leu Thr Ala Gln
                165                 170                 175






<210> 1589
<211> 126
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1589
Met Thr Leu Ala Leu Arg Ser Thr Ala Ala Arg Thr Gln Arg Glu Leu
  1               5                  10                  15

Xaa Arg Arg Arg Asn Pro Ser Thr Ser Thr Ser Pro Gln Ala Gly Gly
             20                  25                  30

Arg Gln Glu Lys Lys Arg Pro Gly Leu Gly Thr Glu Gly Gly Ala Gln
         35                  40                  45

Met His Ile Leu Ala Gly Ile Met Gly Val Leu Lys Gly Val Val Ile
     50                  55                  60

Glu Val Glu Val Xaa Ala Glu Ile Asn Pro Ile Gly Ile Lys Gly Pro
 65                  70                  75                  80

Asp Ala Pro Gly Ser Gly Ser Leu Arg Ile Pro Val Thr Val Gly Val
                 85                  90                  95

Thr Glu Asp Phe Ser Cys Thr Val Asp Leu Glu Ile Ile Met Phe Phe
            100                 105                 110

Lys Cys Ser Gln Ile Gln Leu Gly Gly Tyr Tyr Phe Cys Ile 
        115                 120                 125



<210> 1590
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1590
Met Pro Xaa Leu Leu Ser Xaa Ser Pro Leu Ala Xaa Gly Xaa Gly Gly
  1               5                  10                  15

Ala Ala Pro Trp Val Phe Gly Asp Ser Val Leu Leu Cys Leu Arg Glu
             20                  25                  30

Glu Thr Ala Leu Gly Arg Glu Gly Glu Ala Phe Ile Leu Tyr Cys Cys
         35                  40                  45

Pro Cys Phe Pro Leu Gly Glu Phe Thr Gln Leu Ala Ala Pro Pro His
     50                  55                  60

His Ser Pro Gln Glu Gly His Val Pro Val Phe Cys Pro Pro Leu Leu
 65                  70                  75                  80

Phe Leu Cys Thr Met Ser Leu Ile Phe Pro Ala Arg Glu Ala Asn Pro
                 85                  90                  95

Glu His Ala Pro Val Leu Met Ser Val Ser Ala Gly 
            100                 105



<210> 1591
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1591
Met Gly Gln Leu Lys Phe Asn Thr Ser Glu Glu His His Ala Asp Met
  1               5                  10                  15

Tyr Arg Ser Asp Leu Pro Asn Pro Asp Thr Leu Ser Ala Glu Leu His
             20                  25                  30

Cys Trp Arg Ile Lys Xaa Lys His Arg Gly Lys Asp Ile Glu Leu Pro
         35                  40                  45

Ser Thr Ile Xaa Xaa Ala Leu His Leu Pro Asp Ile Lys Phe Phe Pro
     50                  55                  60

Asn Val Tyr Ala Leu Leu Lys Val Leu Cys Ile Leu Pro Val Met Lys
 65                  70                  75                  80

Val Glu Asn Glu Arg Tyr Glu Asn Gly Arg Lys Arg Leu Lys Ala Tyr
                 85                  90                  95

Leu Arg Asn Thr Leu Thr Asp Gln Xaa Gln Val Thr Trp Leu Cys Leu
            100                 105                 110

Thr 




<210> 1592
<211> 123
<212> PRT
<213> Homo sapiens

<400> 1592
Met Asp Phe Phe Ser Val Gln Asn Ile Leu Val His Ile Pro Ile Gly
  1               5                  10                  15

Ala Gly Gly Tyr Asp Leu Ser Trp Ile Glu Ala Val Gly Thr Ile Ala
             20                  25                  30

Gly Leu Leu Cys Ile Gly Leu Ala Ser Leu Glu Lys Ile Ser Asn Tyr
         35                  40                  45

Phe Phe Gly Leu Ile Asn Val Thr Leu Phe Gly Ile Ile Phe Phe Gln
     50                  55                  60

Ile Gln Leu Tyr Ala Ser Leu Leu Leu Gln Val Phe Phe Phe Ala Ala
 65                  70                  75                  80

Asn Ile Tyr Gly Trp Tyr Ala Trp Ser Arg Gln Thr Ser Gln Asn Glu
                 85                  90                  95

Ala Glu Leu Lys Ile Arg Trp Leu Pro Leu Pro Lys Ala Thr Gln Leu
            100                 105                 110

Val Gly Gly Leu Arg Cys Phe Asp Trp Ser Glu 
        115                 120



<210> 1593
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1593
Met Gly Leu Gly Leu Ser Cys Val Ser Ile Leu Ile Arg Lys Gly Tyr
  1               5                  10                  15

Ala Gln Thr Leu Ala Cys Ser Asp Ser Lys Thr Glu Gly Phe Thr Arg
             20                  25                  30

Pro Thr Pro Gly Lys Trp Ala Ser Leu Leu Pro Met Leu Ser Phe Asn
         35                  40                  45

Leu Cys Asn Leu Pro Val Ser Ile Gly Gly His Leu Thr Pro Pro Lys
     50                  55                  60

Glu Pro Ser Leu Ser Leu Ser Leu Tyr Pro Cys Asn Ser Leu Leu Cys
 65                  70                  75                  80

Ala Phe Pro Gln Ala Gly Pro Ser Ser Thr Leu Xaa Phe Leu Xaa Ala
                 85                  90                  95

Leu Ile Xaa Gly Ile Pro Thr Leu Cys Val Ser Gly Gln Thr Arg Ala
            100                 105                 110

Lys Xaa Gly Ser Cys Leu Arg Tyr Ile Ile 
        115                 120



<210> 1594
<211> 139
<212> PRT
<213> Homo sapiens

<400> 1594
Met Gly Gln Leu Lys Phe Asn Thr Ser Glu Glu His His Ala Asp Met
  1               5                  10                  15

Tyr Arg Ser Asp Leu Pro Asn Pro Asp Thr Leu Ser Ala Glu Leu His
             20                  25                  30

Cys Trp Arg Ile Lys Trp Lys His Arg Gly Lys Asp Ile Glu Leu Pro
         35                  40                  45

Ser Thr Ile Tyr Glu Ala Leu His Leu Pro Asp Ile Lys Phe Phe Pro
     50                  55                  60

Asn Val Tyr Ala Leu Leu Lys Val Leu Cys Ile Leu Pro Val Met Lys
 65                  70                  75                  80

Val Glu Asn Glu Arg Tyr Glu Asn Gly Arg Lys Arg Leu Lys Ala Tyr
                 85                  90                  95

Leu Arg Asn Thr Leu Thr Asn Arg Ser Phe Lys Tyr Val Lys Asn Leu
            100                 105                 110

Tyr Trp Thr Val Thr Arg Asn Tyr Arg Arg Lys Ala Cys Glu Leu Thr
        115                 120                 125

Lys Gln Gly Phe Gln Cys Arg Phe Cys Leu Ser 
    130                 135



<210> 1595
<211> 155
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1595
Met Ser Ser Phe Gly Ala Gly Lys Thr Lys Glu Val Ile Phe Ser Val
  1               5                  10                  15

Glu Asp Gly Ser Val Lys Met Phe Leu Arg Gly Arg Pro Val Pro Met
             20                  25                  30

Met Ile Pro Asp Glu Leu Ala Pro Thr Tyr Ser Leu Asp Thr Arg Ser
         35                  40                  45

Glu Leu Pro Ser Cys Arg Leu Lys Leu Glu Trp Val Tyr Gly Tyr Arg
     50                  55                  60

Gly Arg Asp Cys Arg Ala Asn Leu Tyr Leu Leu Pro Thr Gly Glu Ile
 65                  70                  75                  80

Val Tyr Phe Val Ala Ser Val Ala Val Leu Tyr Ser Val Glu Glu Gln
                 85                  90                  95

Arg Gln Arg His Tyr Leu Gly His Asn Asp Asp Ile Lys Cys Leu Ala
            100                 105                 110

Ile His Pro Asp Met Val Thr Ile Ala Xaa Gly Xaa Val Ala Gly Thr
        115                 120                 125

Xaa Lys Gly Gly Glu Pro Leu Arg Pro Lys Trp Asp Xaa Gly Xaa Ile
    130                 135                 140

Phe Leu Ser Leu Lys Ser Leu Gly Leu Gly Phe 
145                 150                 155



<210> 1596
<211> 127
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1596
Met Met Ala Phe Ala Pro Pro Lys Asn Thr Asp Gly Pro Lys Met Gln
  1               5                  10                  15

Thr Lys Met Ser Thr Trp Thr Pro Leu Asn His Gln Leu Leu Asn Asp
             20                  25                  30

Arg Val Phe Glu Glu Arg Arg Ala Leu Leu Gly Lys Trp Phe Asp Lys
         35                  40                  45

Trp Thr Asp Ser Gln Arg Arg Arg Ile Leu Thr Gly Leu Leu Glu Arg
     50                  55                  60

Cys Ser Leu Ser Gln Gln Lys Phe Cys Cys Arg Lys Leu Ser Arg Glu
 65                  70                  75                  80

Asn Ser Gln Gln Lys Pro Trp Asp Phe Tyr Asn Pro Ser Phe Pro Arg
                 85                  90                  95

Val Leu Ser Phe Ile His Leu Phe Leu Phe Xaa Gly Thr Leu Gly Ser
            100                 105                 110

Xaa Leu Phe Val Val Ala Gln Val Lys Gly Pro Arg Glu Gly Gly 
        115                 120                 125



<210> 1597
<211> 109
<212> PRT
<213> Homo sapiens

<400> 1597
Met Gly Asp Glu Ser Gly Gly Ala Ala Glu Val Gly Arg His Gln Ala
  1               5                  10                  15

Asp Thr Thr Pro Gln Gly Thr Leu Leu Pro Cys Asn Pro Asp Leu Lys
             20                  25                  30

Ser Leu Ser Tyr Asn Lys Glu Leu Gly Thr Thr Glu Gly Lys Arg Lys
         35                  40                  45

Tyr Ser Ala Asn Cys Phe Pro Ile Thr Val Gln Arg Thr His Phe Ala
     50                  55                  60

Met Cys Asn Leu Cys Ser Met Thr Cys Ile Trp Val Cys Leu Val Arg
 65                  70                  75                  80

Tyr Ile Met Trp Cys Pro Cys Tyr Ala Phe Cys Arg Leu Thr Leu Cys
                 85                  90                  95

Leu Thr Ser Pro Ser Val Leu Cys Cys Phe Val Ser Ser 
            100                 105



<210> 1598
<211> 265
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (243)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (257)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (262)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1598
Met Ala Glu Glu Gly Gly Gly Gly Gln Gly Asp Gly Gly Ser Ser Leu
  1               5                  10                  15

Ala Ser Gly Ser Thr Gln Arg Gln Pro Pro Pro Pro Ala Pro Gln His
             20                  25                  30

Pro Gln Pro Gly Ser Gln Ala Leu Pro Ala Pro Ala Leu Ala Pro Asp
         35                  40                  45

Gln Leu Pro Gln Asn Asn Thr Leu Val Ala Leu Pro Ile Val Ala Ile
     50                  55                  60

Glu Asn Ile Leu Ser Phe Met Ser Tyr Asp Glu Ile Ser Gln Leu Arg
 65                  70                  75                  80

Leu Val Cys Lys Arg Met Asp Leu Val Cys Gln Arg Met Leu Asn Gln
                 85                  90                  95

Gly Phe Leu Lys Val Glu Arg Tyr His Asn Leu Cys Gln Lys Gln Val
            100                 105                 110

Lys Ala Gln Leu Pro Arg Arg Glu Ser Glu Arg Arg Asn His Ser Leu
        115                 120                 125

Ala Arg His Ala Asp Ile Leu Ala Ala Val Glu Thr Arg Leu Ser Leu
    130                 135                 140

Leu Asn Met Thr Phe Met Lys Tyr Val Asp Ser Asn Leu Cys Cys Phe
145                 150                 155                 160

Ile Pro Gly Lys Val Ile Asp Glu Ile Xaa Arg Val Xaa Arg Tyr Val
                165                 170                 175

Asn Ser Thr Arg Ala Pro Gln Arg Ala His Glu Val Leu Gln Glu Leu
            180                 185                 190

Arg Asp Ile Ser Ser Met Ala Met Glu Tyr Phe Asp Glu Lys Ile Val
        195                 200                 205

Pro Ile Leu Lys Arg Lys Leu Pro Gly Ser Asp Val Ser Gly Arg Leu
    210                 215                 220

Met Gly Ser Pro Pro Val Pro Gly Pro Ser Gly Ser Pro Asn Asn Asn
225                 230                 235                 240

Ala Ala Xaa Ser Ser Lys Gln Asn Pro Ser Arg Gln Glu Val Tyr Gln
                245                 250                 255

Xaa Pro Ala Ala Gly Xaa Lys Gln Trp 
            260                 265



<210> 1599
<211> 114
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1599
Met Leu Leu Thr Ala Val Gln Leu Leu Tyr Ser Pro Glu Ser Ser Val
  1               5                  10                  15

Arg Thr Lys Leu Ile Gln Leu Pro Val Val Tyr Val Met Leu Met Gln
             20                  25                  30

His Ser Leu Phe Leu Pro Thr Leu Leu Thr Ser Asp Gly Glu Glu Ser
         35                  40                  45

Pro Asp Ser Gln Val Lys Glu Ala Leu Val Asp Leu Met Leu Thr Val
     50                  55                  60

Val Glu Met Cys Pro Ser Val Cys Glu Ser Ser His Phe Ala Val Leu
 65                  70                  75                  80

Leu Gly Gly Tyr Gly Ala Xaa Leu Ser Val Leu Asp Gln Lys Ile Tyr
                 85                  90                  95

Phe Cys Phe Glu Arg Met Ser Arg Lys Val Ser Leu Ile Asn Ser Xaa
            100                 105                 110

Xaa Cys 




<210> 1600
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1600
Met Ala Xaa Leu Gln Gln Leu Arg Val Gln Glu Ala Val Glu Ser Met
  1               5                  10                  15

Val Lys Ser Leu Glu Arg Glu Asn Ile Arg Lys Met Gln Val Ser Gly
             20                  25                  30

Pro Arg Pro Ser Arg Gly Ala Ala Asn Val Lys Asp Gln Lys Gly Glu
         35                  40                  45

Asp Phe Arg Pro Pro Arg Trp Pro Gly His Ala Cys Phe Ser Cys Ala
     50                  55                  60

Gln Pro Arg Phe Thr Gln Arg Gly Phe Leu His Cys Ser Ser Leu Ser
 65                  70                  75                  80

Pro Ala Met Pro Leu Cys Val Ser Val Leu Leu Leu Ser Arg Ser Met
                 85                  90                  95

Arg Phe Pro Asp Ser Ala Pro 
            100



<210> 1601
<211> 173
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1601
Met Xaa Lys Leu Thr Leu Leu Cys Asp Ala Lys Thr Asp Gly Ser Phe
  1               5                  10                  15

Leu Val His His Phe Leu Ser Phe Tyr Leu Lys Ala Asn Cys Lys Val
             20                  25                  30

Cys Phe Val Ala Leu Ile Gln Ser Phe Ser His Tyr Ser Ile Val Gly
         35                  40                  45

Gln Lys Leu Gly Val Ser Leu Thr Met Ala Arg Glu Leu Gly Gln Leu
     50                  55                  60

Val Phe Leu Glu Gly Leu Lys Ser Ala Val Asp Val Val Phe Gln Ala
 65                  70                  75                  80

Gln Lys Glu Pro His Pro Leu Gln Phe Leu Arg Glu Ala Asn Ala Gly
                 85                  90                  95

Asn Leu Lys Pro Leu Phe Glu Phe Val Arg Glu Ala Leu Lys Pro Val
            100                 105                 110

Asp Ser Gly Glu Ala Arg Trp Thr Tyr Pro Val Leu Leu Val Asp Asp
        115                 120                 125

Leu Ser Val Xaa Leu Ser Leu Gly Met Gly Ala Val Ala Val Leu Asp
    130                 135                 140

Phe Ile His Tyr Cys Arg Ala Thr Val Cys Trp Glu Leu Lys Gly Asn
145                 150                 155                 160

Met Val Val Leu Val His Asp Ser Gly Arg Cys Gly Gly 
                165                 170



<210> 1602
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1602
Met Val Lys Met Thr Lys Leu Arg Val Val Gln Tyr Tyr Gly Asn Phe
  1               5                  10                  15

Ser Arg Ser Ala Lys Arg Gly Xaa Leu Arg Leu Leu Glu Glu Gln Arg
             20                  25                  30

Gly Ala Leu Tyr Arg Leu Ser Val Leu Thr Leu Gln Pro Ser Asp Gln
         35                  40                  45

Gly His Tyr Val Cys Arg Val Gln Glu Ile Ser Arg His Arg Asn Lys
     50                  55                  60

Trp Thr Ala Trp Ser Asn Gly Ser Ser Ala Thr Glu Met Arg Val Ile
 65                  70                  75                  80

Ser Leu Lys Ala Ser Glu Glu Ser Ser Phe Glu Lys Thr Lys Glu Thr
                 85                  90                  95

Trp Ala Phe Phe Glu Asp Leu Tyr Val Tyr Ala Val Leu Val Cys Cys
            100                 105                 110

Val Gly Ile Leu Thr Phe Cys Ser Ser Cys Trp Ser Ser Ser Gly Ser
        115                 120                 125

Leu Cys Leu Thr Ser Gly Asn Pro Glu 
    130                 135



<210> 1603
<211> 155
<212> PRT
<213> Homo sapiens

<400> 1603
Met Ala Gly Thr Val Thr Gly Ser Tyr Ala Ser Lys Asp Asp Asn Leu
  1               5                  10                  15

Leu Asn Lys Tyr Leu Ser Glu His Leu Leu Cys Thr Arg His Cys Cys
             20                  25                  30

Arg Cys Leu Gly Tyr Ser His Val Ser Glu Gly Leu Gln Pro Gly Arg
         35                  40                  45

Ile Pro Pro Ile Phe Thr Ser Ser Arg Phe Phe Lys Arg Asp Pro Trp
     50                  55                  60

Leu Tyr Phe Pro Ser Ser Gln Phe Lys His Pro Lys Pro Ala Leu Ser
 65                  70                  75                  80

Pro Leu Gln Thr Gly Arg Trp Asp Trp Leu Pro Gly His Phe Leu Ser
                 85                  90                  95

Leu Ser Phe Ser Gln Ala Phe Leu Pro Pro Gln Glu Thr Asp Phe Ser
            100                 105                 110

Gly Pro Ser Met Pro Ala Thr Leu Ser Val Ser Phe Phe Phe Phe Lys
        115                 120                 125

Val Ile Phe Phe Arg Asn Thr Cys Lys Ile Pro Arg Asn Asn Val Cys
    130                 135                 140

Ala Ser Ala Thr Ser Leu Ser Ser Leu Ile Ser 
145                 150                 155



<210> 1604
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1604
Met Lys Met Val Ala Pro Trp Thr Arg Phe Tyr Ser Asn Ser Cys Cys
  1               5                  10                  15

Leu Cys Cys His Val Arg Thr Gly Thr Ile Leu Leu Gly Val Trp Tyr
             20                  25                  30

Leu Ile Ile Asn Ala Val Val Leu Leu Ile Leu Leu Ser Ala Leu Ala
         35                  40                  45

Asp Pro Asp Gln Tyr Asn Phe Ser Ser Ser Glu Leu Gly Gly Xaa Phe
     50                  55                  60

Glu Phe Met Asp Asp Ala Lys Ile Leu Phe Asn Leu Ser Ala Asp Met
 65                  70                  75                  80

Cys Ile Ala Ile Ala Ile Ser Leu Leu Met Ile Leu Ile Cys Ala Arg
                 85                  90                  95

Leu Leu Lys Glu Arg Thr Ser Asn Ala His Leu Gly Ser Ser His Leu
            100                 105                 110

Leu Leu Pro Asp Leu 
        115



<210> 1605
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1605
Met Pro Xaa Glu Cys Ala Ala Pro Ala Ser Val Thr Leu Xaa Arg Pro
  1               5                  10                  15

Glu Pro Ala Xaa Ala Gln Met Arg Thr Ser Ser Leu Ser Thr Trp Thr
             20                  25                  30

Ala Asp Ser Arg Ser Leu Val Arg Leu Gly Pro Arg Thr Pro Ser Pro
         35                  40                  45

Pro Gln Pro Gly Pro Leu Arg Thr Pro Trp Pro Xaa Leu Gly Ala Ala
     50                  55                  60

Gly Val Gly Met Trp Asn Cys Ser Leu Ser Pro Ser Gly Arg Ile Pro
 65                  70                  75                  80

Xaa Thr Arg Lys Leu Ala Gln Leu Leu Cys Leu Pro Met Pro Cys Val
                 85                  90                  95

Val Met Ser Leu Thr Gln Ala Pro 
            100



<210> 1606
<211> 131
<212> PRT
<213> Homo sapiens

<400> 1606
Met Phe Ile Leu Ala Leu Ser Cys Cys Tyr Phe Pro Thr Leu Thr Cys
  1               5                  10                  15

Ala Ser Ser Leu Ser Pro Glu Glu Glu Leu Arg Trp Ser Tyr Pro Gln
             20                  25                  30

Ile Gly His Glu Lys Leu Glu Phe Gly Lys Gln Gly Leu Gln His Pro
         35                  40                  45

Leu Val Ser Lys Ala Arg Ser Leu Gln Arg Ser Leu Ala Gly Arg Ser
     50                  55                  60

Gln Glu Asn Val Glu Trp Lys Arg Ala Leu Thr Pro Asn Phe Arg Glu
 65                  70                  75                  80

Val Ser Ala Leu Leu Leu Ile Phe Ser Leu Leu Val Leu Leu Glu Cys
                 85                  90                  95

Met Leu Val Ile Cys Ile His Tyr Tyr Asp Cys Val Tyr His Lys Ser
            100                 105                 110

Tyr Lys Ile Lys Met Asp Leu Lys Val Leu Ser Ala Glu Ala Val Ser
        115                 120                 125

Phe Val Leu 
    130



<210> 1607
<211> 303
<212> PRT
<213> Homo sapiens

<400> 1607
Met Gln Ser Pro Leu Trp Met Pro Ser Ser Ser Ser Ile Thr Trp Pro
  1               5                  10                  15

Ser Ser Cys Trp Ser Ser Gly Ser Cys Ser Pro Cys Ser Arg Cys Arg
             20                  25                  30

Trp Ser Arg Ser Thr Asp Gly Glu Ser Arg Phe Tyr Ser Leu Gly His
         35                  40                  45

Leu Ser Ile Gln Arg Ala Ala Leu Val Val Leu Glu Asn Tyr Tyr Lys
     50                  55                  60

Asp Phe Thr Ile Tyr Asn Pro Asn Leu Leu Thr Ala Ser Lys Phe Arg
 65                  70                  75                  80

Ala Ala Lys His Met Ala Gly Leu Lys Val Tyr Asn Val Asp Gly Pro
                 85                  90                  95

Ser Asn Asn Ala Thr Gly Gln Ser Arg Ala Met Ile Ala Ala Ala Ala
            100                 105                 110

Arg Arg Arg Asp Ser Ser His Asn Glu Leu Tyr Tyr Glu Glu Ala Glu
        115                 120                 125

His Glu Arg Arg Val Lys Lys Arg Lys Ala Arg Leu Val Val Ala Val
    130                 135                 140

Glu Glu Ala Phe Ile His Ile Gln Arg Leu Gln Ala Glu Glu Gln Gln
145                 150                 155                 160

Lys Ala Pro Gly Glu Val Met Asp Pro Arg Glu Ala Ala Gln Ala Ile
                165                 170                 175

Phe Pro Ser Met Ala Arg Ala Leu Gln Lys Tyr Leu Arg Ile Thr Arg
            180                 185                 190

Gln Gln Asn Tyr His Ser Met Glu Ser Ile Leu Gln His Leu Ala Phe
        195                 200                 205

Cys Ile Thr Asn Gly Met Thr Pro Lys Ala Phe Leu Glu Arg Tyr Leu
    210                 215                 220

Ser Ala Gly Pro Thr Leu Gln Tyr Asp Lys Asp Arg Trp Leu Ser Thr
225                 230                 235                 240

Gln Trp Arg Leu Val Ser Asp Glu Ala Leu Thr Asn Gly Leu Arg Asp
                245                 250                 255

Gly Ile Val Phe Val Leu Lys Cys Leu Asp Phe Ser Leu Val Val Asn
            260                 265                 270

Val Lys Lys Ile Pro Phe Ile Ile Leu Ser Glu Glu Phe Ile Asp Pro
        275                 280                 285

Lys Ser His Lys Phe Val Leu Arg Leu Gln Ser Glu Thr Ser Val 
    290                 295                 300



<210> 1608
<211> 255
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (227)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (228)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (233)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (238)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (240)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (245)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1608
Met Ala Glu Ala Gln Ser Gly Thr Gly Gln Leu Gln Glu Gln Lys Lys
  1               5                  10                  15

Gly Leu Leu Ile Ala Val Ser Val Ser Val Asp Lys Ile Ile Ser His
             20                  25                  30

Phe Gly Ala Ala Arg Asn Leu Val Gln Lys Ala Gln Leu Gly Asp Ser
         35                  40                  45

Arg Leu Ser Pro Asp Val Gly His Leu Val Leu Thr Thr Leu Cys Pro
     50                  55                  60

Ala Leu His Ala Leu Val Ala Asp Gly Leu Lys Pro Phe Arg Lys Asp
 65                  70                  75                  80

Leu Ile Thr Gly Gln Arg Arg Ser Ser Pro Trp Ser Val Val Glu Ala
                 85                  90                  95

Ser Val Lys Pro Gly Ser Ser Thr Arg Ser Leu Gly Thr Leu Tyr Ser
            100                 105                 110

Gln Val Ser Arg Leu Ala Pro Leu Ser Ser Ser Arg Ser Arg Phe His
        115                 120                 125

Ala Phe Ile Leu Gly Leu Leu Asn Thr Lys Gln Leu Glu Leu Trp Phe
    130                 135                 140

Ser Ser Leu Gln Glu Asp Ala Gly Leu Leu Ser Leu Leu Tyr Leu Pro
145                 150                 155                 160

Thr Gly Phe Phe Ser Leu Ala Arg Gly Gly Cys Pro Ser Leu Ser Thr
                165                 170                 175

Glu Leu Leu Leu Leu Leu Gln Pro Leu Ser Val Leu Thr Phe His Leu
            180                 185                 190

Asp Leu Leu Phe Glu His His His His Leu Pro Leu Gly Pro Pro Gln
        195                 200                 205

Ala Pro Ala Pro Pro Gly Pro Pro Pro Ala Leu Gln Gln Thr Met Gln
    210                 215                 220

Ala Met Xaa Xaa Phe Gly Gly Arg Xaa Gly Xaa Ser Leu Xaa Gly Xaa
225                 230                 235                 240

Ser Lys Glu Val Xaa Ser Asp Pro Leu Ile Phe Lys Thr Ser His 
                245                 250                 255



<210> 1609
<211> 261
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (218)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (227)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (257)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1609
Met Lys Leu Arg Lys Ile Leu Glu Lys Val Glu Ala Ala Ser Gly Phe
  1               5                  10                  15

Thr Ser Glu Glu Lys Asp Pro Glu Glu Phe Leu Asn Ile Leu Phe His
             20                  25                  30

His Ile Leu Arg Val Glu Pro Leu Leu Lys Ile Arg Ser Ala Gly Gln
         35                  40                  45

Lys Val Gln Asp Cys Tyr Phe Tyr Gln Ile Phe Met Glu Lys Asn Glu
     50                  55                  60

Lys Val Gly Val Pro Thr Ile Gln Gln Leu Leu Glu Trp Ser Phe Ile
 65                  70                  75                  80

Asn Ser Asn Leu Lys Phe Ala Glu Ala Pro Ser Cys Leu Ile Ile Gln
                 85                  90                  95

Met Pro Arg Phe Gly Lys Asp Phe Lys Leu Phe Lys Lys Ile Phe Pro
            100                 105                 110

Ser Leu Glu Leu Asn Ile Thr Asp Leu Leu Glu Asp Thr Pro Arg Gln
        115                 120                 125

Cys Arg Ile Cys Gly Gly Leu Ala Met Tyr Glu Cys Arg Glu Cys Tyr
    130                 135                 140

Asp Asp Pro Asp Ile Ser Ala Gly Lys Ile Lys Gln Phe Cys Lys Thr
145                 150                 155                 160

Cys Asn Thr Gln Val His Leu His Pro Lys Arg Leu Asn His Lys Tyr
                165                 170                 175

Asn Pro Val Ser Leu Pro Lys Asp Leu Pro Asp Trp Asp Trp Arg His
            180                 185                 190

Gly Cys Ile Pro Cys Gln Asn Met Glu Leu Phe Ala Val Leu Cys Ile
        195                 200                 205

Xaa Thr Ser His Tyr Val Ala Phe Val Xaa Tyr Gly Lys Asp Asp Ser
    210                 215                 220

Ala Trp Xaa Phe Phe Asp Ser Met Ala Asp Arg Asp Gly Thr Glu Lys
225                 230                 235                 240

Arg Leu Ser Ser Ala Cys Trp His Lys Gly Ser Gly Gly Gln Lys Trp
                245                 250                 255

Xaa Pro His Ser Leu 
            260



<210> 1610
<211> 238
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (227)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1610
Met Pro Asn Thr Asn Gly Ser Ile Gly His Ser Pro Leu Ser Leu Ser
  1               5                  10                  15

Ala Gln Ser Val Met Glu Glu Leu Asn Thr Ala Pro Val Gln Glu Ser
             20                  25                  30

Pro Pro Leu Ala Met Xaa Pro Gly Asn Ser His Gly Leu Glu Val Gly
         35                  40                  45

Ser Leu Ala Glu Val Lys Glu Asn Pro Pro Phe Tyr Gly Val Ile Arg
     50                  55                  60

Trp Ile Gly Gln Pro Pro Gly Leu Asn Glu Val Leu Ala Gly Leu Glu
 65                  70                  75                  80

Leu Glu Asp Glu Cys Ala Gly Cys Thr Asp Gly Thr Phe Arg Gly Thr
                 85                  90                  95

Arg Tyr Phe Thr Cys Ala Leu Lys Lys Ala Leu Phe Val Lys Leu Lys
            100                 105                 110

Ser Cys Arg Pro Asp Ser Arg Phe Ala Ser Leu Gln Pro Val Ser Asn
        115                 120                 125

Gln Ile Glu Arg Cys Asn Ser Leu Ala Phe Gly Gly Tyr Leu Ser Glu
    130                 135                 140

Val Val Glu Glu Asn Thr Pro Pro Lys Met Glu Lys Glu Gly Leu Glu
145                 150                 155                 160

Ile Met Ile Gly Lys Lys Lys Gly Ile Gln Gly His Tyr Asn Ser Cys
                165                 170                 175

Tyr Leu Asp Ser Thr Leu Phe Cys Leu Phe Xaa Phe Ser Ser Val Leu
            180                 185                 190

Asp Thr Val Leu Leu Arg Pro Lys Glu Lys Asn Asp Val Glu Tyr Tyr
        195                 200                 205

Ser Glu Thr Gln Glu Leu Leu Arg Thr Glu Ile Val Asn Pro Leu Arg
    210                 215                 220

Ile Asn Xaa Tyr Trp Glu Gln Asp Arg Ser Asn Pro Lys Leu 
225                 230                 235



<210> 1611
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1611
Met Leu Leu Tyr Ile Ala Asp Asn Leu Ala Cys Phe Pro Tyr Gln Thr
  1               5                  10                  15

Gln Glu Glu Pro Leu Phe Ile Met His His Ile Asp Ile Thr Leu Ser
             20                  25                  30

Val Ser Gly Ser Asn Leu Leu Gln Ser Phe Lys Glu Ser Met Val Lys
         35                  40                  45

Asp Lys Arg Lys Glu Arg Lys Ser Ser Pro Ser Lys Glu Asn Glu Ser
     50                  55                  60

Ser Asp Ser Glu Glu Glu Val Ser Arg Pro Arg Lys Ser Arg Lys Arg
 65                  70                  75                  80

Val Asp Ser Asp Ser Asp Ser Asp Ser Glu Asp Xaa Ile Asn Ser Val
                 85                  90                  95

Met Lys Cys Leu Pro Glu Asn Ser Ala Pro Leu Ile Glu Phe Ala Asn
            100                 105                 110

Val Ser Gln Gly Ile Leu Leu Leu Leu Met Leu Lys Gln His Leu Lys
        115                 120                 125

Asn Leu Cys Gly Phe Ser Asp Ser Lys Ile Gln Lys Tyr Ser Pro Ser
    130                 135                 140

Glu Ser Ala Lys Val Tyr Asp Lys Ala Xaa Thr Glu Asn Gln Xaa Ser
145                 150                 155                 160

Xaa Phe Ile Pro Asn Gln Thr Leu 
                165



<210> 1612
<211> 133
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1612
Met Thr Ser Ser Thr Ser Thr Ala Met Ile Thr Ile Tyr Met Pro Ala
  1               5                  10                  15

Ser Leu Arg Phe Ile Thr Ala Asn Pro Xaa Ser Ser Leu Glu Leu Gln
             20                  25                  30

Met Cys Gly Tyr Leu Ser Leu Tyr Ile Pro Asp Pro Gln Asn Ser Ala
         35                  40                  45

Lys Met Ser Tyr Val Pro Phe Gln Thr Cys Ser Phe Ser His Ile Ala
     50                  55                  60

Tyr Leu Gly Lys Trp Asn Pro His Pro Thr Gly Val Leu Ala Ser Phe
 65                  70                  75                  80

Leu Ile Pro Pro Ala Pro Ala Ser His Ser His Ser Gln Ile Leu Pro
                 85                  90                  95

Gly Ile Pro Cys Arg Xaa Leu Ala Asn Leu Ser Thr Ser Leu Leu Pro
            100                 105                 110

Leu Leu Pro Val Pro Ser Phe Gly Leu Leu Ser Thr Leu Ile Gln Xaa
        115                 120                 125

Ile Thr Lys Val Ser 
    130



<210> 1613
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1613
Met Glu Ile Gly Ile Gly Ser Glu Ala Glu Phe Tyr Ala Arg Val Pro
  1               5                  10                  15

Tyr Pro Val Leu Gly Trp Arg Ile Val Ala Ser Ile Val Trp Ser Val
             20                  25                  30

Leu Phe Leu Pro Ile Cys Thr Thr Val Phe Ile Ile Phe Ser Arg Ile
         35                  40                  45

Asp Xaa Phe His Pro Ile Gln Trp Leu Ser Asp Ser Phe Ser Asp Leu
     50                  55                  60

Tyr Ser Ser Tyr Val Ile Phe Tyr Phe Leu Leu Leu Ser Val Val Ile
 65                  70                  75                  80

Ile Ile Ile Ser Ile Phe Asn Val Glu Phe Tyr Ala Val Val Pro Ser
                 85                  90                  95

Ile Xaa Cys Xaa Arg Leu Xaa Leu Ile Gly 
            100                 105



<210> 1614
<211> 250
<212> PRT
<213> Homo sapiens

<400> 1614
Met Met Val Glu Asn Ile Met Asn Lys Glu Ala Phe Met Asn Gln Glu
  1               5                  10                  15

Ile Thr Lys Ala Phe His Val Arg Lys Ala Asn Arg Ile Lys Glu Cys
             20                  25                  30

Leu Ser Lys Gly Thr Phe Ser Asp Val Thr Phe Lys Leu Asp Asp Gly
         35                  40                  45

Ala Ile Ser Ala His Lys Pro Leu Leu Ile Cys Ser Cys Glu Trp Met
     50                  55                  60

Ala Ala Met Phe Gly Gly Ser Phe Val Glu Ser Ala Asn Ser Glu Val
 65                  70                  75                  80

Tyr Leu Pro Asn Ile Asn Lys Ile Ser Met Gln Ala Val Leu Asp Tyr
                 85                  90                  95

Leu Tyr Thr Lys Gln Leu Ser Pro Asn Leu Asp Leu Asp Pro Leu Glu
            100                 105                 110

Leu Ile Ala Leu Ala Asn Arg Phe Cys Leu Pro His Leu Val Ala Leu
        115                 120                 125

Ala Glu Gln His Ala Val Gln Glu Leu Thr Lys Ala Ala Thr Ser Gly
    130                 135                 140

Val Gly Ile Asp Gly Glu Val Leu Ser Tyr Leu Glu Leu Ala Gln Phe
145                 150                 155                 160

His Asn Ala His Gln Leu Ala Ala Trp Cys Leu His His Ile Cys Thr
                165                 170                 175

Asn Tyr Asn Ser Val Cys Ser Lys Phe Arg Lys Glu Ile Lys Ser Lys
            180                 185                 190

Ser Ala Asp Asn Gln Glu Tyr Phe Glu Arg His Arg Trp Pro Pro Val
        195                 200                 205

Trp Tyr Leu Lys Glu Glu Asp His Tyr Gln Arg Val Lys Arg Glu Arg
    210                 215                 220

Glu Lys Glu Asp Ile Ala Leu Asn Lys His Arg Ser Arg Arg Lys Trp
225                 230                 235                 240

Cys Phe Trp Asn Ser Ser Pro Ala Val Ala 
                245                 250



<210> 1615
<211> 218
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (217)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1615
Met Asp Glu Ala Ser Ala Gln Leu Leu Ala Tyr Lys Glu Lys Gly His
  1               5                  10                  15

Ser Gln Ser Ser Gln Phe Ser Ser Asp Gln Glu Ile Ala His Leu Leu
             20                  25                  30

Pro Glu Asn Val Ser Ala Leu Pro Ala Thr Val Ala Val Ala Ser Pro
         35                  40                  45

His Thr Thr Ser Ala Thr Pro Lys Pro Ala Thr Leu Leu Pro Thr Asn
     50                  55                  60

Ala Ser Val Thr Pro Ser Gly Xaa Ser Gln Pro Gln Leu Ala Thr Thr
 65                  70                  75                  80

Ala Pro Pro Val Thr Xaa Val Thr Xaa Gln Xaa Pro Thr Thr Leu Ile
                 85                  90                  95

Ser Thr Val Phe Thr Arg Gly Cys Gly Tyr Thr Pro Ser Asn Gly Tyr
            100                 105                 110

Asn Arg Val Leu Thr Thr Thr Phe Gln Ala Pro Thr Asp Ser Lys Gly
        115                 120                 125

Ser Leu Glu Thr Ile Pro Phe Thr Glu Ile Ser Asn Leu Thr Leu Asn
    130                 135                 140

Thr Gly Asn Val Tyr Asn Pro Thr Ala Leu Ser Met Ser Asn Val Glu
145                 150                 155                 160

Ser Ser Thr Met Asn Lys Thr Ala Ser Trp Glu Gly Arg Glu Ala Ser
                165                 170                 175

Pro Gly Ser Ser Ser Gln Gly Ser Val Pro Glu Asn Gln Tyr Gly Leu
            180                 185                 190

Pro Phe Glu Lys Trp Leu Leu Ile Gly Ser Leu Leu Phe Gly Val Leu
        195                 200                 205

Phe Leu Val Ile Gly Leu Val Xaa Xaa Gly 
    210                 215



<210> 1616
<211> 253
<212> PRT
<213> Homo sapiens

<400> 1616
Met Ala Ala Ala Arg Ala Thr Thr Pro Ala Asp Gly Glu Glu Pro Ala
  1               5                  10                  15

Pro Glu Ala Glu Ala Leu Ala Ala Ala Arg Glu Arg Ser Ser Arg Phe
             20                  25                  30

Leu Ser Gly Leu Glu Leu Val Lys Gln Gly Ala Glu Ala Arg Val Phe
         35                  40                  45

Arg Gly Arg Phe Gln Gly Arg Ala Ala Val Ile Lys His Arg Phe Pro
     50                  55                  60

Lys Gly Tyr Arg His Pro Ala Leu Glu Ala Arg Leu Gly Arg Arg Arg
 65                  70                  75                  80

Thr Val Gln Glu Ala Arg Ala Leu Leu Arg Cys Arg Arg Ala Gly Ile
                 85                  90                  95

Ser Ala Pro Val Val Phe Phe Val Asp Tyr Ala Ser Asn Cys Leu Tyr
            100                 105                 110

Met Glu Glu Ile Glu Gly Ser Val Thr Val Arg Asp Tyr Ile Gln Ser
        115                 120                 125

Thr Met Glu Thr Glu Lys Thr Pro Gln Gly Leu Ser Asn Leu Ala Lys
    130                 135                 140

Thr Ile Gly Gln Val Leu Ala Arg Met His Asp Glu Asp Leu Ile His
145                 150                 155                 160

Gly Asp Leu Thr Thr Ser Asn Met Leu Leu Lys Pro Pro Leu Glu Gln
                165                 170                 175

Leu Asn Ile Val Leu Ile Asp Phe Gly Leu Ser Phe Ile Ser Ala Leu
            180                 185                 190

Pro Glu Asp Lys Gly Val Asp Leu Tyr Val Leu Glu Lys Ala Phe Leu
        195                 200                 205

Ser Thr His Pro Asn Thr Glu Thr Val Phe Glu Ala Phe Leu Lys Ser
    210                 215                 220

Tyr Ser Thr Ser Ser Lys Lys Ala Arg Pro Val Leu Lys Lys Leu Asp
225                 230                 235                 240

Glu Val Arg Leu Arg Gly Arg Lys Arg Ser Met Val Gly 
                245                 250



<210> 1617
<211> 149
<212> PRT
<213> Homo sapiens

<400> 1617
Met Ala Leu Asp Met Ile Leu Ala Lys Lys Gly Gly Val Cys Val Met
  1               5                  10                  15

Ile Lys Thr Gln Cys Cys Thr Phe Ile Pro Asn Asn Thr Ala Pro Ser
             20                  25                  30

Gly Ser Ile Thr Arg Ala Leu Gln Gly Leu Thr Ala Leu Ser Asn Glu
         35                  40                  45

Leu Ala Lys Asn Ser Gly Val Asn Asp Pro Phe Ser Gly Trp Leu Glu
     50                  55                  60

Arg Trp Phe Gly Lys Trp Lys Gly Ile Ile Ala Ser Ile Leu Thr Ser
 65                  70                  75                  80

Leu Ala Ala Val Ile Gly Val Val Ile Leu Phe Gly Cys Cys Val Thr
                 85                  90                  95

Pro Cys Ile Arg Gly Leu Val Gln Arg Leu Ile Glu Thr Val Leu Thr
            100                 105                 110

Lys Thr Ser Leu Ser Ser Pro Pro Pro Tyr Ser Asp Lys Leu Phe Leu
        115                 120                 125

Leu Glu Asp Gln Val Glu Gln Gln Ser Gln Asp Leu Leu Lys Arg Phe
    130                 135                 140

Glu Glu Glu Gly Pro 
145



<210> 1618
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1618
Met Ala Gln Phe Asp Thr Glu Tyr Xaa Arg Leu Glu Ala Ser Tyr Ser
  1               5                  10                  15

Asp Ser Pro Pro Gly Glu Glu Asp Leu Leu Val His Val Ala Glu Gly
             20                  25                  30

Ser Lys Ser Pro Trp His His Ile Glu Asn Leu Asp Leu Phe Phe Ser
         35                  40                  45

Arg Val Tyr Asn Leu His Gln Lys Asn Gly Phe Thr Cys Met Leu Ile
     50                  55                  60

Gly Glu Ile Phe Ala Thr Phe Leu Val Ser Cys Val Asp Tyr Asp Ile
 65                  70                  75                  80

Leu Phe Ala Asn Lys Met Val Asn His Ser Leu His Pro Thr Glu Pro
                 85                  90                  95

Val Lys Val Thr Leu Pro Asp Ala Phe Leu Pro Ala Gln Val Cys Ser
            100                 105                 110

Ala Arg Ile Gln Glu Asn Gly Ser Leu Ile Thr Ile Leu Val Ile Ala
        115                 120                 125

Gly Val Xaa 
    130



<210> 1619
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1619
Met Ser Ala Ala Arg Pro Gln Phe Ser Ile Asp Asp Ala Phe Glu Leu
  1               5                  10                  15

Ser Leu Glu Asp Gly Gly Pro Gly Pro Glu Ser Ser Gly Val Ala Arg
             20                  25                  30

Phe Gly Pro Leu His Phe Glu Arg Arg Ala Arg Phe Glu Val Ala Asp
         35                  40                  45

Glu Asp Lys Gln Ser Arg Leu Arg Tyr Gln Asn Leu Glu Asn Asp Glu
     50                  55                  60

Asp Gly Ala Gln Ala Ser Pro Glu Pro Asp Gly Gly Val Gly Thr Ser
 65                  70                  75                  80

Ser Gln Trp Ser Phe Ser Thr Ile Ser Ser Ser Thr Gln Arg Ser Tyr
                 85                  90                  95

Asn Xaa Cys Cys Ser Trp Thr Gln Xaa Pro Leu Ile Gln Lys Asn Arg
            100                 105                 110

Arg Val Val Leu Ala Ser Phe Leu Leu Leu Leu Leu Gly Leu Val Leu
        115                 120                 125

Ile Trp Ser Ala Leu Asp Leu Lys Arg Pro Pro Leu Gln Val Ser Pro
    130                 135                 140






<210> 1620
<211> 202
<212> PRT
<213> Homo sapiens

<400> 1620
Met Ala Ala Ala Gly Gly Thr Val Ser Gly Pro Ser Ser Ala Cys Lys
  1               5                  10                  15

Pro Val Arg Ser Thr Thr Gly Ala Pro Ser Thr Thr Ala Asp Ser Lys
             20                  25                  30

Leu Ser Asn Gln Val Ser Thr Ile Val Ser Leu Leu Ser Thr Leu Cys
         35                  40                  45

Arg Gly Ser Pro Val Val Thr His Asp Leu Leu Arg Ser Glu Leu Pro
     50                  55                  60

Asp Ser Ile Glu Ser Ala Leu Gln Gly Asp Glu Arg Cys Val Leu Asp
 65                  70                  75                  80

Thr Met Arg Leu Val Asp Phe Leu Leu Val Leu Leu Phe Glu Gly Arg
                 85                  90                  95

Lys Ala Leu Pro Lys Ser Ser Ala Gly Ser Thr Gly Arg Ile Pro Gly
            100                 105                 110

Leu Arg Arg Leu Asp Ser Ser Gly Glu Arg Ser His Arg Gln Leu Ile
        115                 120                 125

Asp Cys Ile Arg Ser Lys Asp Thr Asp Ala Leu Ile Asp Ala Ile Asp
    130                 135                 140

Thr Gly Ala Phe Glu Val Asn Phe Met Asp Asp Val Gly Gln Thr Leu
145                 150                 155                 160

Leu Asn Trp Ala Ser Ala Phe Gly Thr Gln Glu Met Val Glu Phe Leu
                165                 170                 175

Cys Glu Arg Gly Ala Asp Val Asn Arg Gly Gln Ser His His His Tyr
            180                 185                 190

Ile Met Leu His Val Leu Glu Asp Leu Lys 
        195                 200



<210> 1621
<211> 168
<212> PRT
<213> Homo sapiens

<400> 1621
Met Gln Gln Tyr Asn Leu Cys Val Tyr Arg Trp Leu Ser Glu Pro Gln
  1               5                  10                  15

Ile Thr Val Asn Phe Glu Ser Ser Gly Glu Gly Ala Cys Ser Met Ser
             20                  25                  30

Leu Val Cys Ser Val Glu Lys Ala Gly Met Asp Met Thr Tyr Ser Trp
         35                  40                  45

Leu Ser Arg Gly Asp Ser Thr Tyr Thr Phe His Glu Gly Pro Val Leu
     50                  55                  60

Ser Thr Ser Trp Arg Pro Gly Asp Ser Ala Leu Ser Tyr Thr Cys Arg
 65                  70                  75                  80

Ala Asn Asn Pro Ile Ser Asn Val Ser Ser Cys Pro Ile Pro Asp Gly
                 85                  90                  95

Pro Phe Tyr Ala Asp Pro Asn Tyr Ala Ser Glu Lys Pro Ser Thr Ala
            100                 105                 110

Phe Cys Leu Leu Ala Lys Gly Leu Leu Ile Phe Leu Leu Leu Val Ile
        115                 120                 125

Leu Ala Met Gly Leu Trp Val Ile Arg Val Gln Lys Arg His Lys Met
    130                 135                 140

Pro Arg Met Lys Lys Leu Met Arg Asn Arg Met Lys Leu Arg Lys Glu
145                 150                 155                 160

Ala Lys Pro Gly Ser Ser Pro Ala 
                165



<210> 1622
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1622
Met Pro Arg Ala Leu Asp Leu Gln Ala Gln Leu Leu Asp Ser Gly Cys
  1               5                  10                  15

Gln Gln Thr Ser Pro Leu Asp Pro Asp Asn His Asn Ala Trp Ile Leu
             20                  25                  30

Gly Pro Pro Ser Leu Asp Pro Arg Ser Pro His Ser Thr His Trp Ile
         35                  40                  45

Pro Ala Leu Val Phe Gly Phe Leu Phe Phe Phe Asn Leu Xaa Thr Gly
     50                  55                  60

Ser Gln Xaa Pro Ser Ala Xaa Cys Gln Asp Pro Cys Ile Ser Ser Thr
 65                  70                  75                  80

Thr Pro Ser Asn Pro Lys Ala Leu Glu Ser Arg Phe Pro Lys Pro Leu
                 85                  90                  95

Pro Thr Arg Phe Trp Xaa Leu 
            100



<210> 1623
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1623
Met Gln His Lys Val Leu Leu Leu Gly Ser Lys Ser Ala Asn Gln Ser
  1               5                  10                  15

Leu Pro Gln Glu Asp Ser Ser Thr Asp Asp Pro Gly Glu Gln Val Gln
             20                  25                  30

Ala Val Arg Ser Ser Thr Gln Asp Phe Leu Xaa His Val Ile Leu Lys
         35                  40                  45

Asn Thr Trp Phe Arg Val Tyr Tyr Gly Val Leu Gly Leu Phe Pro Ala
     50                  55                  60

Leu Ala Ser Val Val Lys Leu Ala Val Pro Phe Tyr Leu Gly Asp Ser
 65                  70                  75                  80

Ala Pro Ser His Phe Thr His Gln Leu Leu Ile Ile Ser Pro Ala Leu
                 85                  90                  95

Leu Asn His Leu Phe Leu Asp Thr Leu Pro Ala Ser Cys Ile Thr 
            100                 105                 110



<210> 1624
<211> 391
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (389)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1624
Met Pro Gly Arg Ile Ile Asn Gly Leu Lys Thr Val Gly Val Asn Asn
  1               5                  10                  15

Pro Val Phe Leu Leu Asp Glu Val Asp Lys Leu Gly Lys Ser Leu Gln
             20                  25                  30

Gly Asp Pro Ala Ala Ala Leu Leu Glu Val Leu Asp Pro Glu Gln Asn
         35                  40                  45

His Asn Phe Thr Asp His Tyr Leu Asn Val Ala Phe Asp Leu Ser Gln
     50                  55                  60

Val Leu Phe Ile Ala Thr Ala Asn Thr Thr Ala Thr Ile Pro Ala Ala
 65                  70                  75                  80

Leu Leu Asp Arg Met Glu Ile Ile Gln Val Pro Gly Tyr Thr Gln Glu
                 85                  90                  95

Glu Lys Ile Glu Ile Ala His Arg His Leu Ile Pro Lys Gln Leu Glu
            100                 105                 110

Gln His Gly Leu Thr Pro Gln Gln Ile Gln Ile Pro Gln Val Thr Thr
        115                 120                 125

Leu Asp Ile Ile Thr Arg Tyr Thr Arg Glu Ala Gly Val Arg Ser Leu
    130                 135                 140

Asp Arg Lys Leu Gly Ala Ile Cys Arg Ala Val Ala Val Lys Val Ala
145                 150                 155                 160

Glu Gly Gln His Lys Glu Ala Xaa Leu Asp Arg Ser Asp Val Thr Glu
                165                 170                 175

Arg Glu Gly Cys Arg Glu His Ile Leu Glu Asp Glu Lys Pro Glu Ser
            180                 185                 190

Xaa Ser Asp Thr Thr Asp Leu Ala Leu Pro Pro Glu Met Pro Ile Leu
        195                 200                 205

Ile Asp Phe His Ala Leu Lys Asp Ile Leu Gly Pro Pro Met Tyr Glu
    210                 215                 220

Met Glu Val Ser Gln Arg Leu Ser Gln Pro Gly Val Ala Ile Gly Leu
225                 230                 235                 240

Ala Trp Thr Pro Leu Gly Gly Glu Ile Met Phe Val Glu Ala Ser Arg
                245                 250                 255

Met Asp Gly Glu Gly Gln Leu Thr Leu Thr Gly Gln Leu Gly Asp Val
            260                 265                 270

Met Lys Glu Ser Ala His Leu Ala Ile Ser Trp Leu Arg Ser Asn Ala
        275                 280                 285

Lys Lys Tyr Gln Leu Thr Asn Ala Phe Gly Ser Phe Asp Leu Leu Asp
    290                 295                 300

Asn Thr Asp Ile His Leu His Phe Pro Ala Gly Ala Val Thr Lys Asp
305                 310                 315                 320

Gly Pro Ser Ala Gly Val Thr Ile Val Thr Cys Leu Ala Ser Leu Phe
                325                 330                 335

Ser Gly Arg Leu Val Arg Ser Asp Val Ala Met Thr Gly Glu Ile Thr
            340                 345                 350

Leu Arg Gly Leu Val Leu Pro Val Gly Gly Ile Lys Asp Lys Val Leu
        355                 360                 365

Ala Ala His Arg Ala Gly Leu Lys Gln Val Ile Ile Pro Arg Arg Asn
    370                 375                 380

Glu Lys Asp Leu Xaa Gly Ile 
385                 390



<210> 1625
<211> 248
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (201)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (228)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (229)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (245)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1625
Met Tyr Lys Leu Leu Leu Phe Asp Leu Leu Thr Val Leu Ala Val Ala
  1               5                  10                  15

Leu Xaa Ile Gln Phe Pro Arg Lys Leu Leu Cys Gly Leu Cys Pro Gly
             20                  25                  30

Ala Leu Gly Arg Leu Ala Gly Thr Gln Glu Phe Gln Val Pro Asp Glu
         35                  40                  45

Val Leu Gly Leu Ile Tyr Ala Gln Thr Val Val Trp Val Gly Ser Phe
     50                  55                  60

Phe Cys Pro Leu Leu Pro Leu Leu Asn Thr Val Lys Phe Leu Leu Leu
 65                  70                  75                  80

Phe Tyr Leu Lys Lys Leu Thr Leu Phe Ser Thr Cys Ser Pro Ala Ala
                 85                  90                  95

Arg Thr Phe Arg Ala Ser Ala Ala Asn Phe Phe Phe Pro Leu Val Leu
            100                 105                 110

Leu Leu Gly Leu Ala Ile Ser Ser Val Pro Leu Leu Tyr Ser Ile Xaa
        115                 120                 125

Leu Ile Pro Pro Ser Lys Leu Cys Gly Pro Phe Arg Gly Gln Ser Ser
    130                 135                 140

Ile Trp Ala Gln Ile Pro Glu Ser Ile Ser Ser Leu Pro Glu Thr Thr
145                 150                 155                 160

Gln Asn Phe Leu Phe Phe Leu Gly Thr Gln Ala Phe Ala Val Pro Leu
                165                 170                 175

Leu Leu Ile Ser Ser Ile Leu Met Ala Tyr Thr Val Ala Leu Ala Asn
            180                 185                 190

Ser Tyr Gly Arg Leu Ile Ser Glu Xaa Lys Arg Gln Arg Gln Thr Glu
        195                 200                 205

Ala Gln Asn Lys Val Phe Leu Ala Arg Arg Ala Val Ala Leu Xaa Leu
    210                 215                 220

His Gln Thr Xaa Xaa Phe Xaa Pro Pro Gln Xaa His Val Pro Gly Phe
225                 230                 235                 240

Ser Arg Thr Pro Xaa Ala His Trp 
                245



<210> 1626
<211> 129
<212> PRT
<213> Homo sapiens

<400> 1626
Met Asn Pro Ala Thr Thr Leu Pro Gly Leu Met Pro Leu Pro Ala Gly
  1               5                  10                  15

Leu Pro Asn Leu Pro Asn Leu Asn Leu Asn Leu Pro Ala Pro His Ile
             20                  25                  30

Met Pro Gly Val Gly Leu Pro Glu Leu Val Asn Pro Gly Leu Pro Pro
         35                  40                  45

Leu Pro Ser Met Pro Pro Arg Asn Leu Pro Gly Ile Ala Pro Pro Leu
     50                  55                  60

Arg Thr Glu Ser Ala Thr Pro Pro Gln Ser Ala Arg Ser Leu Phe Leu
 65                  70                  75                  80

Arg Leu Trp Met Pro Met Leu Leu Ser His Leu Asn Phe Glu Pro Phe
                 85                  90                  95

Phe Gly Ile Gly Val Val Tyr Leu Thr Thr Gly Ala Cys Leu Glu Thr
            100                 105                 110

Gln Thr Ile Ile Asn Phe Ile Leu Val Cys Thr Val Ser Val Gly Ile
        115                 120                 125

Leu 




<210> 1627
<211> 142
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1627
Met Asn Glu Gln Met Met Asn Ile Gly Asn Glu Glu Gln Gly Pro Asp
  1               5                  10                  15

Ser Ser Ser Trp Gly Asp Asn Tyr Leu Gly Tyr Ser Leu Gly Leu Gly
             20                  25                  30

Ser Arg Arg Ala Trp Ser Pro Tyr Gly Leu Cys Leu Ser Gln Pro Ser
         35                  40                  45

Leu Ser Phe Leu Gln Glu Thr Ser His Val Leu Trp Ala Leu Trp Arg
     50                  55                  60

Ala Leu Ala Leu His Xaa Gly Ala Gly Arg His Cys Leu Pro Cys Pro
 65                  70                  75                  80

Leu Pro Ala Ala Pro Ala Leu Val Cys Arg Leu Gly Pro Gly Cys Leu
                 85                  90                  95

Leu Leu Gly Val Trp Pro Arg Ala Pro Val Lys Pro Trp Arg His Cys
            100                 105                 110

Val Cys Val Met Gly Ser Glu Gly Leu Val Gly Val Ser Thr Gly Ala
        115                 120                 125

Ala His Cys Gln Ser Ser Tyr Phe Leu Trp Xaa Xaa Trp Cys 
    130                 135                 140



<210> 1628
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1628
Met Ala Ala Pro Ser Gln Gln Arg Leu Val Val Xaa Ser Val Ser Pro
  1               5                  10                  15

Gln Ser Arg Ala Ser Leu Ala Ala Arg Phe Gln Leu Asn Pro Thr Asp
             20                  25                  30

Thr Ala Arg Lys Leu Thr Ser Phe Phe Lys Lys Ile Gly Val His Phe
         35                  40                  45

Val Phe Asp Thr Ala Phe Ser Arg His Phe Ser Leu Leu Glu Ser Gln
     50                  55                  60

Arg Glu Phe Val Arg Arg Phe Arg Gly Gln Ala Asp Cys Arg Gln Ala
 65                  70                  75                  80

Leu Pro Leu Leu Ala Ser Ala Cys Pro Gly Val Leu Met Val Arg Val
                 85                  90                  95

Val Gly Glu Ser Ser Ser Ser Ala Val Glu Thr 
            100                 105



<210> 1629
<211> 248
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (222)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1629
Met Glu Ala Gly Val Lys Leu Gly Met Arg Ser Ile Pro Ile Ala Thr
  1               5                  10                  15

Ala Cys Thr Ile Tyr His Lys Phe Phe Cys Glu Thr Asn Leu Asp Ala
             20                  25                  30

Tyr Asp Pro Tyr Leu Ile Ala Met Ser Ser Ile Tyr Leu Ala Gly Lys
         35                  40                  45

Val Glu Glu Gln His Leu Arg Thr Arg Asp Ile Ile Asn Val Ser Asn
     50                  55                  60

Arg Tyr Phe Asn Pro Ser Gly Glu Pro Leu Glu Leu Asp Ser Arg Phe
 65                  70                  75                  80

Trp Glu Leu Arg Asp Ser Ile Val Gln Cys Glu Leu Leu Met Leu Arg
                 85                  90                  95

Val Leu Arg Phe Gln Val Ser Phe Gln His Pro His Lys Tyr Leu Leu
            100                 105                 110

His Tyr Leu Val Ser Leu Gln Asn Trp Leu Asn Arg His Ser Trp Gln
        115                 120                 125

Arg Thr Pro Val Ala Val Thr Ala Trp Ala Leu Leu Arg Asp Ser Tyr
    130                 135                 140

His Gly Ala Leu Cys Leu Arg Phe Gln Ala Gln His Ile Ala Val Ala
145                 150                 155                 160

Val Leu Tyr Leu Ala Leu Gln Val Tyr Gly Val Glu Val Pro Ala Glu
                165                 170                 175

Val Glu Ala Glu Lys Pro Leu Gly Gly Arg Cys Leu Met Thr Thr Leu
            180                 185                 190

Pro Ser Gln Ser Leu Ile Ile Leu Cys Leu Ile Ser Phe Arg Phe Ile
        195                 200                 205

Pro Trp Thr Gln Arg Ser Pro Lys Val Leu Ala Gln Gly Xaa Pro Lys
    210                 215                 220

Arg Ser Pro Gly Trp Ser Ala Ala Trp Gly His Cys Gln His Val Gly
225                 230                 235                 240

Met Thr Gly Trp Ser Pro Gln Asp 
                245



<210> 1630
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1630
Met Asn Ser Tyr Phe Tyr Lys Phe Met Ile Xaa Leu Leu Lys Arg Phe
  1               5                  10                  15

Ser Ser Glu Arg Lys Leu Leu Glu Val Arg Gly Pro Phe Ile Ile Arg
             20                  25                  30

Ser Ala Leu Ala Ala Arg Phe Leu Leu Phe Leu Pro Arg Pro Arg Leu
         35                  40                  45

Phe Thr Phe Thr Pro Phe Lys Cys Gln Ser Ser His Leu Leu Phe Pro
     50                  55                  60

Phe Ser Leu Leu Leu Phe Leu Thr Phe Gly Ser Val Lys Arg Met Glu
 65                  70                  75                  80

Glu Gly Cys Pro Phe His Asp Trp Val Gly Trp Met Leu Xaa Gly His
                 85                  90                  95

Gly Asn Arg Thr Gly Ser Val Leu Asn Val Phe Cys Arg Thr Thr Xaa
            100                 105                 110

Ile Gln Phe Phe Ala 
        115



<210> 1631
<211> 259
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1631
Met Lys Gln Leu Ile Gly Ser Ser Asn Leu Phe Val Met Gln Val Glu
  1               5                  10                  15

Met Asp Ile Tyr Thr Ala Leu Lys Lys Trp Met Phe Leu Gln Leu Val
             20                  25                  30

Pro Ser Trp Asn Gly Ser Leu Lys Gln Leu Leu Thr Glu Thr Asp Val
         35                  40                  45

Trp Phe Ser Lys Gln Arg Lys Asp Phe Glu Gly Met Ala Phe Leu Glu
     50                  55                  60

Thr Glu Gln Gly Lys Pro Phe Val Ser Val Phe Arg His Leu Arg Leu
 65                  70                  75                  80

Xaa Tyr Ile Ile Ser Asp Leu Xaa Ser Ala Xaa Ile Ile Glu Gln Asp
                 85                  90                  95

Ala Val Val Pro Ser Glu Trp Leu Ser Ser Val Tyr Lys Gln Gln Trp
            100                 105                 110

Phe Ala Met Leu Arg Ala Glu Gln Asp Ser Glu Val Gly Pro Gln Glu
        115                 120                 125

Ile Asn Lys Glu Glu Leu Glu Gly Asn Ser Met Arg Cys Gly Arg Lys
    130                 135                 140

Leu Ala Lys Asp Gly Glu Tyr Cys Trp Arg Trp Thr Gly Phe Asn Phe
145                 150                 155                 160

Gly Phe Asp Leu Leu Val Thr Tyr Thr Asn Arg Tyr Ile Ile Phe Lys
                165                 170                 175

Arg Asn Thr Leu Asn Gln Pro Cys Ser Gly Ser Val Ser Leu Gln Pro
            180                 185                 190

Arg Arg Ser Ile Ala Phe Arg Leu Arg Leu Ala Ser Phe Asp Ser Ser
        195                 200                 205

Gly Lys Leu Ile Cys Ser Arg Thr Thr Gly Tyr Gln Ile Leu Thr Leu
    210                 215                 220

Glu Lys Asp Gln Glu Gln Val Val Met Asn Leu Asp Ser Arg Leu Leu
225                 230                 235                 240

Ile Phe Pro Leu Tyr Ile Cys Cys Asn Phe Leu Tyr Ile Ser Pro Glu
                245                 250                 255

Lys Lys Asn 




<210> 1632
<211> 376
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (59)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (149)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (364)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1632
Met Leu Pro Leu Ser Ile Lys Asp Asp Glu Tyr Lys Pro Pro Xaa Phe
  1               5                  10                  15

Asn Leu Phe Gly Lys Ile Ser Gly Trp Phe Arg Ser Ile Leu Ser Asp
             20                  25                  30

Lys Thr Ser Arg Asn Leu Phe Phe Phe Leu Cys Leu Asn Leu Ser Phe
         35                  40                  45

Ala Phe Val Glu Leu Leu Tyr Gly Ile Trp Xaa Asn Cys Leu Gly Leu
     50                  55                  60

Ile Ser Asp Ser Phe His Met Phe Phe Asp Ser Thr Ala Ile Leu Ala
 65                  70                  75                  80

Gly Leu Ala Ala Ser Val Ile Ser Lys Trp Arg Asp Asn Asp Ala Phe
                 85                  90                  95

Ser Tyr Gly Tyr Val Arg Ala Glu Val Leu Ala Gly Phe Val Asn Gly
            100                 105                 110

Leu Phe Leu Ile Phe Thr Ala Phe Phe Ile Phe Ser Glu Gly Val Glu
        115                 120                 125

Arg Ala Leu Ala Pro Pro Asp Val His His Glu Arg Leu Leu Leu Val
    130                 135                 140

Ser Ile Leu Gly Xaa Val Val Asn Leu Ile Gly Ile Phe Val Phe Lys
145                 150                 155                 160

His Gly Gly His Gly His Ser His Gly Ser Gly His Gly His Ser His
                165                 170                 175

Ser Leu Phe Asn Gly Ala Leu Asp Gln Ala His Gly His Val Asp His
            180                 185                 190

Cys His Ser His Glu Val Lys His Gly Ala Ala His Ser His Asp His
        195                 200                 205

Ala His Gly His Gly His Phe His Ser His Asp Gly Pro Ser Leu Lys
    210                 215                 220

Glu Thr Thr Gly Pro Ser Arg Gln Ile Leu Gln Gly Val Phe Leu His
225                 230                 235                 240

Ile Leu Ala Asp Thr Leu Gly Ser Ile Gly Val Ile Ala Ser Ala Ile
                245                 250                 255

Met Met Gln Asn Phe Gly Leu Met Ile Ala Asp Pro Ile Cys Ser Ile
            260                 265                 270

Leu Ile Ala Ile Leu Ile Val Val Ser Val Ile Pro Leu Leu Arg Glu
        275                 280                 285

Ser Val Gly Ile Leu Met Gln Arg Thr Pro Pro Leu Leu Glu Asn Ser
    290                 295                 300

Leu Pro Gln Cys Tyr Gln Arg Val Gln Gln Leu Gln Gly Val Tyr Ser
305                 310                 315                 320

Leu Gln Glu Gln His Phe Trp Thr Leu Cys Ser Asp Val Tyr Val Gly
                325                 330                 335

Thr Leu Lys Leu Ile Val Ala Pro Asp Ala Asp Ala Arg Trp Ile Leu
            340                 345                 350

Ser Gln Thr His Asn Ile Phe Thr Gln Ala Gly Xaa Arg Gln Leu Tyr
        355                 360                 365

Val Gln Ile Asp Phe Ala Ala Met 
    370                 375



<210> 1633
<211> 132
<212> PRT
<213> Homo sapiens

<400> 1633
Met Ile Ser Ile Thr Glu Trp Gln Lys Ile Gly Val Gly Ile Thr Gly
  1               5                  10                  15

Phe Gly Ile Phe Phe Ile Leu Phe Gly Thr Leu Leu Tyr Phe Asp Ser
             20                  25                  30

Val Leu Leu Ala Phe Gly Asn Leu Leu Phe Leu Thr Gly Leu Ser Leu
         35                  40                  45

Ile Ile Gly Leu Arg Lys Thr Phe Trp Phe Phe Phe Gln Arg His Lys
     50                  55                  60

Leu Lys Gly Thr Ser Phe Leu Leu Gly Gly Val Val Ile Val Leu Leu
 65                  70                  75                  80

Arg Trp Pro Leu Leu Gly Met Phe Leu Glu Thr Tyr Gly Phe Phe Ser
                 85                  90                  95

Leu Phe Lys Gly Phe Phe Pro Val Ala Phe Gly Phe Leu Gly Asn Val
            100                 105                 110

Cys Asn Ile Pro Phe Leu Gly Ala Leu Phe Arg Arg Leu Gln Gly Thr
        115                 120                 125

Ser Ser Met Val 
    130



<210> 1634
<211> 101
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1634
Met Ala Ala Xaa Gln Gln Pro Ser Ser Leu Ser Tyr Arg Thr Thr Gly
  1               5                  10                  15

Ser Thr Tyr Leu His Pro Leu Ser Glu Leu Leu Gly Ile Pro Leu Asp
             20                  25                  30

Gln Val Asn Phe Val Val Cys Gln Leu Val Ala Leu Phe Ala Ala Phe
         35                  40                  45

Trp Phe Arg Ile Tyr Leu Arg Pro Gly Thr Thr Ser Ser Asp Val Arg
     50                  55                  60

His Ala Val Ala Thr Ile Phe Gly Ile Tyr Phe Val Ile Phe Cys Phe
 65                  70                  75                  80

Gly Trp Tyr Ser Val His Leu Phe Val Leu Val Leu Met Cys Tyr Ala
                 85                  90                  95

Ile Met Gly His Cys 
            100



<210> 1635
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1635
Met Gln Thr Ser Thr Leu Phe Phe Gln Ile Lys Ile Ala Ser Leu Ile
  1               5                  10                  15

Ser Ile Ile Tyr Phe Lys Leu Glu Pro Gln Ser Phe Phe Asn Phe Ser
             20                  25                  30

Asn Cys Phe Asn Tyr Xaa Ala His Xaa Ile Ala Lys Ile Thr Lys Phe
         35                  40                  45

Lys Phe Xaa Val Lys Phe Ile Leu Gln Leu Val Lys Leu Xaa Ile Xaa
     50                  55                  60

Ile Phe Phe Pro Leu Pro Pro Leu Val Ile Asn Thr Leu Arg Pro Thr
 65                  70                  75                  80

Glu Val Ile Val Leu Lys Val Cys Asp Cys Asp Leu His Gln Arg Phe
                 85                  90                  95

Glu Pro Arg Thr Lys Thr Ala Leu 
            100



<210> 1636
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1636
Met Arg Arg Arg Arg Arg Ile Pro Glu Ser Pro Gly Val Ser Gly Val
  1               5                  10                  15

Ala Ser Arg Gln Pro Gly Gly Arg Asn Ile Ser Xaa Met Ala His Ser
             20                  25                  30

Lys Thr Arg Thr Asn Asp Gly Lys Ile Thr Tyr Pro Pro Gly Val Lys
         35                  40                  45

Glu Ile Ser Asp Lys Ile Ser Lys Glu Glu Met Val Arg Arg Leu Lys
     50                  55                  60

Met Val Val Lys Thr Phe Met Asp Met Asp Gln Asp Ser Glu Glu Glu
 65                  70                  75                  80

Lys Glu Leu Tyr Leu Asn Leu Ala Leu His Leu Ala Ser Asp Phe Phe
                 85                  90                  95

Leu Lys His Pro Asp Lys Asp Val Arg Leu Leu Val Ala Cys Cys Leu
            100                 105                 110

Ala Asp Ile Phe Arg Ile Tyr Ala Pro Glu Ala Pro Tyr Thr Ser Pro
        115                 120                 125

Asp Lys Leu Xaa Asp Ile Phe Met Phe Ile Thr Arg Gln Leu Xaa Gly
    130                 135                 140

Leu Xaa Asp 
145



<210> 1637
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1637
Met Val Lys Leu Gly Cys Ser Phe Ser Gly Lys Pro Gly Lys Asp Pro
  1               5                  10                  15

Gly Asp Gln Asp Gly Ala Ala Xaa Asp Ser Val Pro Leu Ile Ser Pro
             20                  25                  30

Leu Asp Ile Ser Gln Leu Gln Pro Pro Leu Pro Asp Gln Val Val Ile
         35                  40                  45

Lys Thr Gln Thr Glu Tyr Gln Leu Ser Ser Pro Asp Gln Gln Asn Phe
     50                  55                  60

Pro Asp Leu Glu Gly Gln Arg Leu Xaa Leu Gln Pro Pro Xaa Gly Arg
 65                  70                  75                  80

Ala Gln Leu Pro Thr Ala Arg Met Ile Ala Phe Ala Met Ala Leu Leu
                 85                  90                  95

Gly Cys Val Leu Ile Met Tyr Lys Ala Ile Trp Tyr Asp Gln Phe Thr
            100                 105                 110

Cys Pro Asp Gly Phe Leu Leu Arg His Lys Ile Cys Thr Pro Leu Thr
        115                 120                 125

Leu Gly Asp Val Leu His Gly Asp Gly Pro Arg Ala Pro Pro Gln His
    130                 135                 140

Pro Gly Gly His Arg Gly Tyr Pro Leu Ser Arg Lys His Gly Xaa Glu
145                 150                 155                 160

Glu Ala Arg Arg Pro Gly 
                165



<210> 1638
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1638
Met Leu Val Gln Asn Thr Ile Thr Xaa Lys Cys Gln Tyr Arg Cys Ile
  1               5                  10                  15

Ser Ser Ala Val Ser Arg Ser Leu Ala Ser Pro His Gly Val Arg Arg
             20                  25                  30

Leu Ile Ser Pro Ala Asp Asn Pro Gly Gly Val Thr Val Ser Asn Cys
         35                  40                  45

Cys Gly Thr Ile Ala Ser Val Gly Leu His Arg Arg Ala Ser Ala Glu
     50                  55                  60

Cys Arg Arg His Asp Trp Ser Ser Leu Pro Ser Met Tyr Arg Ile Ser
 65                  70                  75                  80

Ala His Asn Gly Leu Arg Ile Arg Phe Phe Ile Arg Ser Ser Leu Ile
                 85                  90                  95

Val Leu Arg Val Val Phe Leu Val Lys Leu Asn Arg Ile Met Ser 
            100                 105                 110



<210> 1639
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1639
Met Thr Arg Val Tyr Tyr Arg Glu Ala Met Gly Ala Phe Ile Val Phe
  1               5                  10                  15

Asp Val Thr Arg Pro Ala Thr Phe Glu Ala Val Ala Lys Trp Lys Asn
             20                  25                  30

Asp Leu Asp Ser Lys Leu Ser Leu Pro Asn Gly Lys Pro Val Ser Val
         35                  40                  45

Val Leu Leu Ala Asn Lys Cys Asp Gln Gly Lys Asp Val Leu Met Asn
     50                  55                  60

Asn Gly Leu Lys Met Asp Gln Phe Cys Lys Glu His Gly Phe Val Gly
 65                  70                  75                  80

Trp Phe Glu Thr Ser Ala Lys Glu Asn Ile Asn Ile Asp Glu Ala Ser
                 85                  90                  95

Arg Cys Leu Val Lys His Ile Leu Ala Asn Glu Cys Asp Leu Met Glu
            100                 105                 110

Ser Ile Glu Pro Asp Val Val Lys Pro His Leu Thr Ser Thr Lys Val
        115                 120                 125

Ala Ser Cys Xaa Trp Leu Cys Xaa Ile Leu Val Gly Thr Phe Ala Gly
    130                 135                 140

Val Trp 
145



<210> 1640
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1640
Met Pro Ala Phe Ile Gln Met Gly Arg Asp Lys Asn Phe Ser Ser Leu
  1               5                  10                  15

His Thr Val Phe Cys Ala Thr Gly Gly Xaa Ala Tyr Lys Phe Glu Gln
             20                  25                  30

Asp Phe Leu Thr Ile Gly Asp Leu Gln Leu Cys Lys Leu Asp Glu Leu
         35                  40                  45

Asp Cys Leu Ile Lys Gly Ile Leu Tyr Ile Asp Ser Val Gly Phe Asn
     50                  55                  60

Gly Arg Ser Gln Cys Tyr Tyr Phe Glu Asn Pro Ala Asp Ser Glu Lys
 65                  70                  75                  80

Cys Gln Lys Leu Pro Phe Asp Leu Lys Asn Pro Tyr Pro Leu Leu Leu
                 85                  90                  95

Val Asn Ile Gly Ser Gly Val Ser Ile Leu Ala Val Tyr Ser Xaa Xaa
            100                 105                 110

Asn Tyr Xaa Arg Val Thr Gly Thr Ser Leu Gly Gly Gly Leu Phe Leu
        115                 120                 125

Val Leu Leu 
    130



<210> 1641
<211> 291
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1641
Met Ala Phe Leu Asp Thr Thr Gly Cys Leu Ile Pro Pro Ala Tyr Glu
  1               5                  10                  15

Pro Trp Arg Glu His Asn Val Pro Glu Glu Lys Asp Glu Lys Glu Lys
             20                  25                  30

Leu Lys Lys Arg Arg Pro Val Ser Val Ser Pro Ser Ser Ser Gln Glu
         35                  40                  45

Ile Ser Glu Asn Gln Tyr Ala Val Ile Cys Ser Glu Lys Gln Ala Lys
     50                  55                  60

Val Ile Ser Leu Pro Thr Gln Asn Cys Ala Tyr Lys Gln Asn Ile Thr
 65                  70                  75                  80

Glu Thr Ser Phe Val Leu Arg Gly Asp Ile Val Ala Leu Ser Asn Ser
                 85                  90                  95

Ile Cys Leu Ala Cys Phe Cys Ala Asn Gly His Ile Met Thr Phe Ser
            100                 105                 110

Leu Pro Ser Leu Arg Pro Leu Leu Xaa Val Tyr Tyr Leu Pro Leu Thr
        115                 120                 125

Asn Met Arg Xaa Ala Arg Thr Phe Cys Phe Thr Asn Asn Gly Gln Ala
    130                 135                 140

Leu Tyr Leu Val Ser Pro Thr Glu Ile Gln Arg Leu Thr Tyr Ser Gln
145                 150                 155                 160

Glu Thr Cys Glu Asn Leu Gln Glu Met Leu Gly Glu Leu Phe Thr Pro
                165                 170                 175

Val Glu Thr Pro Glu Ala Pro Asn Arg Gly Phe Phe Lys Gly Leu Phe
            180                 185                 190

Gly Gly Gly Ala Gln Ser Leu Asp Arg Glu Glu Leu Phe Gly Glu Ser
        195                 200                 205

Ser Ser Gly Lys Ala Ser Arg Ser Leu Ala Gln His Ile Pro Gly Pro
    210                 215                 220

Gly Gly Ile Glu Gly Val Lys Gly Ala Ala Ser Gly Val Val Gly Glu
225                 230                 235                 240

Leu Ala Arg Ala Arg Leu Ala Leu Asp Glu Arg Gly Gln Lys Leu Gly
                245                 250                 255

Asp Leu Glu Glu Arg Thr Ala Ala Met Leu Ser Ser Ala Glu Ser Phe
            260                 265                 270

Ser Lys His Ala His Glu Ile Met Leu Lys Tyr Lys Asp Lys Lys Trp
        275                 280                 285

Tyr Gln Phe 
    290



<210> 1642
<211> 134
<212> PRT
<213> Homo sapiens

<400> 1642
Met Lys Lys His Ser Ala Arg Val Ala Pro Leu Ser Ala Cys Asn Ser
  1               5                  10                  15

Pro Val Leu Thr Leu Thr Lys Val Glu Gly Glu Glu Arg Pro Arg Asp
             20                  25                  30

Ser Pro Gly Pro Ala Glu Ala Gln Ala Pro Ala Gly Val Glu Ala Gly
         35                  40                  45

Gly Arg Ala Ser Arg Arg Cys Trp Thr Cys Ser Arg Ala Gln Leu Lys
     50                  55                  60

Lys Ile Phe Trp Gly Val Ala Val Val Leu Cys Val Cys Ser Ser Trp
 65                  70                  75                  80

Ala Gly Ser Thr Gln Leu Ala Lys Leu Thr Phe Arg Lys Phe Asp Ala
                 85                  90                  95

Pro Phe Thr Leu Thr Trp Phe Ala Thr Asn Trp Asn Phe Leu Phe Phe
            100                 105                 110

Pro Leu Tyr Tyr Val Gly His Val Cys Lys Ser Thr Glu Lys Gln Ser
        115                 120                 125

Val Lys Gln Arg Tyr Arg 
    130



<210> 1643
<211> 205
<212> PRT
<213> Homo sapiens

<400> 1643
Met Leu Thr Ala Ile Ala Leu Phe Leu Trp Ser Ala Ser Asn Glu Ile
  1               5                  10                  15

Ile Gly Val Gln Ser Leu Gln Asn Gly Cys Met Asn Arg Phe Lys Asn
             20                  25                  30

Ala Leu Asn Ser Cys Asp Pro Trp Val Gln Ala Lys Cys Tyr Gln Leu
         35                  40                  45

Leu Leu Ser Val Phe Gln His Ser Asn Arg Ala Leu Ser Thr Pro Tyr
     50                  55                  60

Ile His Ser Leu Ala Pro Ile Val Val Glu Lys Leu Lys Ala Val Glu
 65                  70                  75                  80

Arg Asn Arg Pro Ala Ser Asn Ile Glu Leu Leu Ala Val Gln Glu Gly
                 85                  90                  95

Ile Lys Val Leu Glu Thr Leu Val Ala Leu Gly Glu Glu Gln Asn Arg
            100                 105                 110

Val Gln Leu Leu Ala Leu Leu Val Pro Thr Leu Ile Ser Tyr Leu Leu
        115                 120                 125

Asp Glu Asn Ser Phe Ala Ser Ala Ser Ser Ala Ser Lys Asp Leu His
    130                 135                 140

Glu Phe Ala Leu Gln Asn Leu Met His Ile Gly Pro Leu Tyr Pro His
145                 150                 155                 160

Ala Phe Lys Thr Val Met Gly Ala Ala Pro Glu Leu Lys Val Arg Leu
                165                 170                 175

Glu Thr Ala Val Arg Ala Ser Gln Ala Ser Lys Ala Lys Ala Ala Ala
            180                 185                 190

Arg Gln Pro Ala Pro Ala Ile His Ser Ala Pro Thr Ile 
        195                 200                 205



<210> 1644
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1644
Met Val Leu Glu Ser Val Ala Arg Ile Val Lys Val Gln Leu Pro Ala
  1               5                  10                  15

Tyr Leu Lys Arg Leu Pro Val Pro Glu Ser Ile Thr Gly Phe Ala Arg
             20                  25                  30

Leu Thr Val Ser Glu Trp Leu Arg Leu Leu Pro Phe Leu Gly Val Leu
         35                  40                  45

Ala Leu Leu Gly Tyr Leu Ala Val Arg Pro Phe Leu Pro Lys Lys Lys
     50                  55                  60

Gln Gln Lys Asp Ser Leu Ile Asn Leu Lys Ile Gln Lys Glu Asn Pro
 65                  70                  75                  80

Lys Val Val Asn Glu Ile Asn Ile Glu Asp Leu Cys Leu Thr Lys Ala
                 85                  90                  95

Ala Tyr Cys Xaa Cys Trp Arg Ser Lys Thr Phe Pro Ala Cys Asp Gly
            100                 105                 110

Ser His Asn Lys His Met Asn 
        115



<210> 1645
<211> 318
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1645
Met Phe Leu Asp Leu Asp Glu Thr Arg Asn Leu Ser Ala His Lys Ile
  1               5                  10                  15

Ser Gly Asn Phe Leu Met Glu Phe Gln Val Lys Asn Val Pro Ser Glu
             20                  25                  30

Arg Ile Ala Thr Gln Lys Ile Leu Ser Val Leu Gly Glu Cys Leu Asp
         35                  40                  45

His Phe Gly Pro Gly Cys Val Gly Val Gln Lys Ile Leu Asn Ala Arg
     50                  55                  60

Cys Pro Leu Val Arg Phe Ser His Gln Ala Ser Gly Phe Gln Cys Asp
 65                  70                  75                  80

Leu Thr Thr Asn Asn Arg Ile Ala Leu Thr Ser Ser Glu Leu Leu Tyr
                 85                  90                  95

Ile Tyr Gly Ala Leu Asp Ser Arg Val Arg Ala Leu Val Xaa Ser Val
            100                 105                 110

Arg Cys Trp Ala Arg Ala His Ser Leu Thr Ser Ser Ile Pro Gly Ala
        115                 120                 125

Trp Ile Thr Asn Phe Ser Leu Thr Met Met Val Ile Phe Phe Leu Gln
    130                 135                 140

Arg Arg Ser Pro Pro Ile Leu Pro Thr Leu Asp Ser Leu Lys Thr Leu
145                 150                 155                 160

Ala Asp Ala Glu Asp Lys Cys Val Ile Glu Gly Asn Asn Cys Thr Phe
                165                 170                 175

Val Arg Asp Leu Ser Arg Ile Lys Pro Ser Gln Asn Thr Glu Thr Leu
            180                 185                 190

Glu Leu Leu Leu Lys Glu Phe Phe Glu Tyr Phe Gly Asn Phe Ala Phe
        195                 200                 205

Asp Lys Asn Ser Ile Asn Ile Arg Gln Gly Arg Glu Gln Asn Lys Pro
    210                 215                 220

Asp Ser Ser Pro Leu Tyr Ile Gln Asn Pro Phe Glu Thr Ser Leu Asn
225                 230                 235                 240

Ile Ser Lys Asn Val Ser Gln Ser Gln Leu Gln Lys Phe Val Asp Leu
                245                 250                 255

Ala Arg Glu Ser Ala Trp Ile Leu Gln Gln Glu Asp Thr Asp Arg Pro
            260                 265                 270

Ser Ile Ser Ser Asn Arg Pro Trp Gly Leu Val Ser Leu Leu Leu Pro
        275                 280                 285

Ser Ala Pro Asn Arg Lys Ser Phe Thr Lys Lys Lys Ser Asn Lys Phe
    290                 295                 300

Ala Ile Glu Thr Val Lys Asn Leu Leu Gly Ile Phe Lys Arg 
305                 310                 315



<210> 1646
<211> 446
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (326)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (439)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1646
Met Ala Asp Arg Gly Arg Pro Arg Thr Ala Gly Leu Ala Glu Lys Ser
  1               5                  10                  15

Pro Leu Gln Thr Ile Gly Glu Glu Gln Thr Gln Asn Pro Tyr Thr Glu
             20                  25                  30

Leu Leu Val Leu Lys Ala His His Asp Ile Val Arg Phe Leu Val Gln
         35                  40                  45

Leu Asp Asp Tyr Arg Phe Ala Ser Ala Gly Asp Asp Gly Ile Val Val
     50                  55                  60

Val Trp Asn Ala Gln Thr Gly Glu Lys Leu Leu Glu Leu Asn Gly His
 65                  70                  75                  80

Thr Gln Lys Ile Thr Ala Ile Ile Thr Phe Pro Ser Leu Glu Ser Cys
                 85                  90                  95

Glu Glu Lys Asn Gln Leu Ile Leu Thr Ala Ser Ala Asp Arg Thr Val
            100                 105                 110

Ile Val Trp Asp Gly Asp Thr Thr Arg Gln Val Gln Arg Ile Ser Cys
        115                 120                 125

Phe Gln Ser Thr Val Lys Cys Leu Thr Val Leu Gln Arg Leu Asp Val
    130                 135                 140

Trp Leu Ser Gly Gly Asn Asp Leu Cys Val Trp Asn Arg Lys Leu Asp
145                 150                 155                 160

Leu Leu Cys Lys Thr Ser His Leu Ser Asp Thr Gly Ile Ser Ala Leu
                165                 170                 175

Val Glu Ile Pro Lys Asn Cys Val Val Ala Ala Val Gly Lys Glu Leu
            180                 185                 190

Ile Ile Phe Arg Leu Val Ala Pro Thr Glu Gly Ser Leu Glu Trp Asp
        195                 200                 205

Ile Leu Glu Val Lys Arg Leu Leu Asp His Gln Asp Asn Ile Leu Ser
    210                 215                 220

Leu Ile Asn Val Asn Asp Leu Ser Phe Val Thr Gly Ser His Val Gly
225                 230                 235                 240

Glu Leu Ile Ile Trp Asp Ala Leu Asp Trp Thr Met Gln Ala Tyr Glu
                245                 250                 255

Arg Asn Phe Trp Asp Pro Ser Pro Gln Leu Asp Thr Gln Gln Glu Ile
            260                 265                 270

Lys Leu Cys Gln Lys Ser Asn Asp Ile Ser Ile His His Phe Thr Cys
        275                 280                 285

Asp Glu Glu Asn Val Phe Ala Ala Val Gly Arg Gly Leu Tyr Val Tyr
    290                 295                 300

Ser Leu Gln Met Lys Arg Val Ile Ala Cys Gln Lys Thr Ala His Asp
305                 310                 315                 320

Ser Asn Val Leu His Xaa Ala Arg Leu Pro Asn Arg Gln Leu Ile Ser
                325                 330                 335

Cys Ser Glu Asp Gly Ser Val Arg Ile Trp Glu Leu Arg Glu Lys Gln
            340                 345                 350

Gln Leu Ala Ala Glu Pro Val Pro Thr Gly Phe Phe Asn Met Trp Gly
        355                 360                 365

Phe Gly Arg Val Ser Lys Gln Ala Ser Gln Pro Val Lys Lys Gln Gln
    370                 375                 380

Glu Asn Ala Thr Ser Cys Ser Leu Glu Leu Ile Gly Asp Leu Ile Gly
385                 390                 395                 400

His Ser Ser Ser Val Glu Met Phe Leu Tyr Phe Glu Asp His Gly Leu
                405                 410                 415

Val Thr Cys Ser Ala Asp His Leu Ile Ile Leu Trp Lys Asn Gly Glu
            420                 425                 430

Arg Glu Ser Gly Leu Pro Xaa Phe Lys Ile Ile Ser Lys Ile 
        435                 440                 445



<210> 1647
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1647
Met Gly Lys Lys Ser Arg Ala Val Pro Gly Pro Xaa Xaa Ile Leu Gln
  1               5                  10                  15

Leu Ser Pro Pro Gly Pro Arg Gly Ser Thr Pro Gly Arg Asp Pro Glu
             20                  25                  30

Pro Glu Pro Asp Thr Glu Pro Asp Ser Thr Ala Ala Val Pro Ser Gln
         35                  40                  45

Pro Ala Pro Ser Ala Ala Thr Thr Thr Ala Val Thr Ala Ala Ala Ala
     50                  55                  60

Ser Asp Asp Ser Pro Ser Glu Gly Lys Asp Glu Gln Glu Ala Val Gln
 65                  70                  75                  80

Glu Val Pro Arg Val Val Gln Asn Pro Pro Lys Pro Val Met Thr Thr
                 85                  90                  95

Arg Pro Thr Ala Val Lys Ala Thr Gly Met Leu Leu Phe Cys Phe Leu
            100                 105                 110

His Phe Phe Ser His Val Phe His 
        115                 120



<210> 1648
<211> 161
<212> PRT
<213> Homo sapiens

<400> 1648
Met Pro Gly Leu Ser Ala Ala Leu Thr Asp Cys Ser Ser Leu Pro His
  1               5                  10                  15

Gly Phe Pro Phe Phe Leu Glu Tyr Leu Phe Phe Arg Gly Asn Met Gln
             20                  25                  30

Leu Gly Leu Lys Thr Phe Pro Pro Ile Ser Pro Thr Gln Pro Arg Leu
         35                  40                  45

Gly Phe Ser Gly Glu Leu Arg Ser Leu Ser Val Phe Ile Phe His Pro
     50                  55                  60

Phe Ile Val Thr Ser Phe Val Ile Leu Phe Phe Phe Gly Gly Asp Gly
 65                  70                  75                  80

Val Ile Val Asn Leu Ile Ser Val Ser Tyr Leu Phe Ala Ser Pro Pro
                 85                  90                  95

Ser Pro Pro His Glu Leu Leu Pro Ser Arg Gly Leu Ala Gln Leu Ala
            100                 105                 110

Leu Gly Thr Arg Glu Arg Thr Asp Ser Gly Pro Pro Gln Leu Ser Pro
        115                 120                 125

Pro Ser Leu Trp Lys Gly Gly Trp Gly Ser Gly Ala Ser Ser Trp Ala
    130                 135                 140

Leu Cys Glu Ala Trp Pro Pro Leu Pro Thr Leu Ala Leu Asp Cys Tyr
145                 150                 155                 160

Ser 




<210> 1649
<211> 178
<212> PRT
<213> Homo sapiens

<400> 1649
Met Arg Asn Pro Ala Ile Gln Asn Asp Phe Ser Tyr Tyr Arg Arg Thr
  1               5                  10                  15

Ile Ser Arg Asn Arg Ile Asn Asn Met His Leu Asp Ile Glu Asn Glu
             20                  25                  30

Val Asn Asn Glu Met Ala Asn Arg Met Ser Leu Phe Tyr Ala Glu Ala
         35                  40                  45

Thr Pro Met Leu Lys Thr Leu Ser Asn Ala Thr Met His Phe Val Ser
     50                  55                  60

Glu Asn Lys Thr Leu Pro Ile Glu Asn Thr Thr Asp Cys Leu Ser Thr
 65                  70                  75                  80

Met Thr Ser Val Cys Lys Val Met Leu Glu Thr Pro Glu Tyr Arg Ser
                 85                  90                  95

Arg Phe Thr Ser Glu Glu Thr Leu Met Phe Cys Met Arg Val Met Val
            100                 105                 110

Gly Val Ile Ile Leu Tyr Asp His Val His Pro Val Gly Ala Phe Cys
        115                 120                 125

Lys Thr Ser Lys Ile Asp Met Lys Gly Cys Ile Lys Val Leu Lys Glu
    130                 135                 140

Gln Ala Pro Asp Ser Val Glu Gly Leu Leu Asn Ala Leu Arg Phe Thr
145                 150                 155                 160

Thr Lys His Leu Asn Asp Glu Ser Thr Ser Lys Gln Ile Arg Ala Met
                165                 170                 175

Leu Gln 




<210> 1650
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1650
Met Ala Ser Tyr Ser Gly Phe Ser Gly Leu Leu Glu Ile Arg Tyr Gly
  1               5                  10                  15

Pro Gly His Arg Ser Cys Leu Pro Gln Phe Ala Phe Phe Pro Gln Pro
             20                  25                  30

Pro Leu Pro Arg Pro Arg Ile Cys Met Xaa Val Leu Ala Glu Leu Leu
         35                  40                  45

Glu Leu Xaa Cys Pro Glu Gln Ser Leu Xaa Asp Ala Ile Xaa Leu Asp
     50                  55                  60

Leu Phe Cys His Ala Leu Ile Phe Cys Arg Gln Gln Gly Phe Ser Leu
 65                  70                  75                  80

Glu Gln Thr Ser Ala Ala Cys Ala Leu Leu Gln Asp Leu His Lys Ala
                 85                  90                  95

Cys Ile Gly His Ile His Val Leu Arg Ala Tyr Ile Lys Thr Gln Val
            100                 105                 110

Asn Lys Glu Xaa Glu Gln Xaa Gln Gly Xaa Val Glu Xaa Arg Leu Lys
        115                 120                 125

Ala Ser Glu Glu Arg Phe Ser Ser Asn 
    130                 135



<210> 1651
<211> 117
<212> PRT
<213> Homo sapiens

<400> 1651
Met Leu Leu Ile Phe Glu Thr Asp Leu Pro Phe His Leu Leu Ile Lys
  1               5                  10                  15

Lys Lys Lys Asn Pro Lys Gly Lys Lys Pro Thr Arg Cys Gly Ser Ala
             20                  25                  30

Cys His Ala Ala Val Cys Val Thr Val Val Leu Leu Phe Pro Lys Glu
         35                  40                  45

Val Leu Leu Ser Phe Ser Phe Phe Asn Phe Val Asn Phe Gln Val Leu
     50                  55                  60

Phe Cys Trp Lys Thr Val Gln Arg Thr Glu Thr Asn Gly Gln Cys His
 65                  70                  75                  80

His Ser Ala Tyr Trp Ala Glu Ala Ser Val Glu Arg Trp His Arg Gly
                 85                  90                  95

Cys Arg Gly Arg Leu Gly Phe Arg Arg Val Gly Cys His Phe Thr Phe
            100                 105                 110

Cys Leu Ala Ala Arg 
        115



<210> 1652
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1652
Met Cys Val His Ile Tyr Met Tyr Ile Leu Cys Val His Ile Tyr Ile
  1               5                  10                  15

Leu Tyr Ala Cys Ile Tyr Thr Xaa Tyr Thr Tyr Thr Leu Cys Val Tyr
             20                  25                  30

Ile Tyr Thr His Cys Val Val Xaa Tyr Val Tyr Thr Leu Cys Val Tyr
         35                  40                  45

Thr Tyr Ile His Cys Val Cys Ile Tyr Ile His Ile Leu Cys Val Cys
     50                  55                  60

Val Tyr Ile Tyr Ile Tyr Ser Val Cys Val Cys Ile Cys Ile Tyr Cys
 65                  70                  75                  80

Val Cys Ile Tyr Ile Ala Gly Tyr Ile Tyr Thr Cys Ile His Ile Tyr
                 85                  90                  95

Val Cys Val Val Tyr Ile Tyr Thr His Thr His Thr Met His Thr Gln
            100                 105                 110






<210> 1653
<211> 149
<212> PRT
<213> Homo sapiens

<400> 1653
Met Lys Gln Asn Leu Asp Glu Leu Gly Ile Gly Thr Tyr His Asn Ile
  1               5                  10                  15

Ala Phe Ile His Pro Asp Thr Pro Ile Ile Lys Ala Leu Asn Ile Phe
             20                  25                  30

Val Glu Arg Arg Ile Ser Ala Leu Pro Val Val Asp Glu Ser Gly Lys
         35                  40                  45

Val Val Asp Ile Tyr Ser Lys Phe Asp Val Ile Asn Leu Ala Ala Glu
     50                  55                  60

Lys Thr Tyr Asn Asn Leu Asp Ile Thr Val Thr Gln Ala Leu Gln His
 65                  70                  75                  80

Arg Ser Gln Tyr Phe Glu Gly Val Val Lys Cys Asn Lys Leu Glu Ile
                 85                  90                  95

Leu Glu Thr Ile Val Asp Arg Ile Val Arg Ala Glu Val His Arg Leu
            100                 105                 110

Val Val Val Asn Glu Ala Asp Ser Ile Val Gly Ile Ile Ser Leu Ser
        115                 120                 125

Asp Ile Leu Gln Ala Leu Ile Leu Thr Pro Ala Gly Ala Lys Gln Lys
    130                 135                 140

Glu Thr Glu Thr Glu 
145



<210> 1654
<211> 336
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (246)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (253)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1654
Met Leu Gln Arg Gly Leu Trp Pro Trp Arg Thr Arg Leu Leu Pro Thr
  1               5                  10                  15

Pro Gly Thr Trp Arg Pro Ala Arg Pro Trp Pro Leu Pro Pro Pro Pro
             20                  25                  30

Gln Val Leu Arg Val Lys Leu Cys Gly Asn Val Lys Tyr Tyr Gln Ser
         35                  40                  45

His His Tyr Ser Thr Val Val Pro Pro Asp Glu Ile Thr Val Ile Tyr
     50                  55                  60

Arg His Gly Leu Pro Leu Val Thr Leu Thr Leu Pro Ser Arg Lys Glu
 65                  70                  75                  80

Arg Cys Gln Phe Val Val Lys Pro Met Leu Ser Thr Val Gly Ser Phe
                 85                  90                  95

Leu Gln Asp Leu Gln Asn Glu Asp Lys Gly Ile Lys Thr Ala Ala Ile
            100                 105                 110

Phe Thr Ala Asp Gly Asn Met Ile Ser Ala Ser Thr Leu Met Asp Ile
        115                 120                 125

Leu Leu Met Asn Asp Phe Lys Leu Val Ile Asn Lys Ile Ala Tyr Asp
    130                 135                 140

Val Gln Cys Pro Lys Arg Glu Lys Pro Ser Asn Glu His Thr Ala Glu
145                 150                 155                 160

Met Glu His Met Lys Ser Leu Val His Arg Leu Phe Thr Ile Leu His
                165                 170                 175

Leu Glu Glu Ser Gln Lys Lys Arg Glu His His Leu Leu Glu Lys Ile
            180                 185                 190

Asp His Leu Lys Glu Gln Leu Gln Pro Leu Glu Gln Val Lys Ala Gly
        195                 200                 205

Ile Glu Ala His Ser Glu Ala Lys Thr Ser Gly Leu Leu Trp Ala Gly
    210                 215                 220

Leu Ala Leu Leu Ser Ile Gln Gly Gly Ala Leu Ala Trp Leu Thr Trp
225                 230                 235                 240

Trp Val Tyr Ser Trp Xaa Ile Met Glu Pro Val Thr Xaa Phe Ile Thr
                245                 250                 255

Phe Ala Asn Ser Met Val Phe Phe Ala Tyr Phe Ile Val Thr Arg Gln
            260                 265                 270

Asp Tyr Thr Tyr Ser Ala Val Lys Ser Arg Gln Phe Leu Gln Phe Phe
        275                 280                 285

His Lys Lys Ser Lys Gln Gln His Phe Asp Val Gln Gln Tyr Asn Lys
    290                 295                 300

Leu Lys Glu Asp Leu Ala Lys Ala Lys Glu Ser Leu Lys Gln Ala Arg
305                 310                 315                 320

His Ser Leu Cys Leu Gln Met Gln Val Glu Glu Leu Asn Glu Lys Asn
                325                 330                 335






<210> 1655
<211> 247
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (222)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1655
Met Pro Glu Glu Ile Ala Arg Tyr Tyr Lys His Tyr Val Lys Val Met
  1               5                  10                  15

Gly Leu Gln Lys Asn Phe Arg Glu Asn Thr Tyr Ile Thr Ser Val Ser
             20                  25                  30

Arg Leu Tyr Arg Asp Gln Asp Asp Asp Asp Ile Gln Asp Arg Asp Ile
         35                  40                  45

Ser Thr Lys His Leu Gln Ile Glu Lys Ser Asn Phe Ile Lys Arg Asn
     50                  55                  60

Trp Glu Ile Arg Gly Tyr Gln Arg Ile Ala Asp Gly Ser His Val Pro
 65                  70                  75                  80

Phe Cys Leu Phe Ala Glu Asn Val Ala Leu Ala Thr Gly Thr Leu Asp
                 85                  90                  95

Ser Pro Ala His Leu Glu Ile Glu Gly Glu Asp Phe Pro Phe Xaa Phe
            100                 105                 110

His Ser Met Pro Glu Phe Gly Ala Ala Xaa Asn Lys Gly Lys Leu Arg
        115                 120                 125

Gly Lys Val Asp Pro Val Leu Ile Val Gly Ser Gly Leu Thr Ala Ala
    130                 135                 140

Asp Ala Val Leu Cys Ala Tyr Asn Ser Asn Ile Pro Val Ile His Val
145                 150                 155                 160

Phe Arg Arg Arg Val Thr Asp Pro Ser Leu Ile Phe Lys Gln Leu Pro
                165                 170                 175

Lys Lys Leu Tyr Pro Glu Tyr His Lys Val Tyr His Met Met Cys Thr
            180                 185                 190

Gln Ser Tyr Ser Val Asp Ser Asn Leu Leu Ser Asp Tyr Thr Ser Phe
        195                 200                 205

Pro Glu His Arg Val Leu Ser Phe Lys Ser Asp Met Lys Xaa Val Leu
    210                 215                 220

Gln Ser Val Ser Gly Leu Lys Lys Ile Phe Lys Leu Ser Ala Ala Val
225                 230                 235                 240

Ser Ile Asp Arg Phe Ser Ser 
                245



<210> 1656
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1656
Met Gly Gly Asn Gly Ser Thr Cys Lys Pro Asp Thr Glu Arg Gln Gly
  1               5                  10                  15

Thr Leu Ser Thr Ala Ala Pro Thr Thr Ser Pro Ala Pro Cys Leu Ser
             20                  25                  30

Asn His His Asn Lys Lys His Leu Ile Leu Ala Phe Cys Ala Gly Val
         35                  40                  45

Leu Leu Thr Leu Leu Leu Ile Ala Phe Ile Phe Leu Ile Ile Lys Ser
     50                  55                  60

Tyr Arg Lys Tyr His Ser Lys Pro Gln Ala Pro Asp Pro His Ser Asp
 65                  70                  75                  80

Pro Pro Ala Lys Leu Ser Ser Ile Pro Gly Glu Ser Xaa Thr Tyr Ala
                 85                  90                  95

Ser Thr Xaa Phe Lys Xaa Ser Xaa Xaa Lys Ser Asn His Leu Ala Glu
            100                 105                 110

Asn His Ser Gly Arg Leu 
        115



<210> 1657
<211> 444
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1657
Met Cys Xaa Glu Ile Arg Ala Val Phe Ser Arg Arg Tyr Leu Leu Gln
  1               5                  10                  15

Asn Thr Ala Leu Glu Val Phe Met Ala Asn Arg Thr Ser Val Met Phe
             20                  25                  30

Asn Phe Pro Asp Gln Ala Thr Val Lys Lys Val Val Tyr Ser Leu Pro
         35                  40                  45

Arg Val Gly Val Gly Thr Ser Tyr Gly Leu Pro Gln Ala Arg Arg Ile
     50                  55                  60

Ser Leu Ala Thr Pro Arg Gln Leu Tyr Lys Ser Ser Asn Met Thr Gln
 65                  70                  75                  80

Arg Trp Gln Arg Arg Xaa Ile Ser Asn Phe Glu Tyr Leu Met Xaa Xaa
                 85                  90                  95

Asn Thr Ile Ala Gly Arg Thr Tyr Asn Asp Leu Asn Gln Tyr Pro Val
            100                 105                 110

Phe Pro Trp Val Leu Thr Asn Tyr Glu Ser Glu Glu Leu Asp Leu Thr
        115                 120                 125

Leu Pro Gly Asn Phe Arg Asp Leu Ser Lys Pro Ile Gly Ala Leu Asn
    130                 135                 140

Pro Lys Arg Ala Val Phe Tyr Ala Glu Arg Tyr Glu Thr Trp Glu Asp
145                 150                 155                 160

Asp Gln Ser Pro Pro Tyr His Tyr Asn Thr His Tyr Ser Thr Ala Thr
                165                 170                 175

Ser Thr Leu Ser Trp Leu Val Arg Ile Glu Pro Phe Thr Thr Phe Phe
            180                 185                 190

Leu Asn Ala Asn Asp Gly Lys Phe Asp His Pro Asp Arg Thr Phe Ser
        195                 200                 205

Ser Val Ala Arg Ser Trp Arg Thr Ser Gln Arg Asp Thr Ser Asp Val
    210                 215                 220

Lys Glu Leu Ile Pro Glu Phe Tyr Tyr Leu Pro Glu Met Phe Val Asn
225                 230                 235                 240

Ser Asn Gly Tyr Asn Leu Gly Val Arg Glu Asp Glu Val Val Val Asn
                245                 250                 255

Asp Val Asp Leu Pro Pro Trp Ala Lys Lys Pro Glu Asp Phe Val Arg
            260                 265                 270

Ile Asn Arg Met Ala Leu Glu Ser Glu Phe Val Ser Cys Gln Leu His
        275                 280                 285

Gln Trp Ile Asp Leu Ile Phe Gly Tyr Lys Gln Arg Gly Pro Glu Ala
    290                 295                 300

Val Arg Ala Leu Asn Val Phe His Tyr Leu Thr Tyr Glu Gly Ser Val
305                 310                 315                 320

Asn Leu Asp Ser Ile Thr Asp Pro Val Leu Arg Glu Ala Met Glu Ala
                325                 330                 335

Gln Ile Gln Asn Phe Gly Gln Thr Pro Ser Gln Leu Leu Ile Glu Pro
            340                 345                 350

His Pro Pro Arg Ser Ser Ala Met His Leu Cys Phe Leu Pro Gln Ser
        355                 360                 365

Pro Leu Met Phe Lys Asp Gln Met Gln Gln Asp Val Ile Met Val Leu
    370                 375                 380

Lys Phe Pro Ser Asn Ser Pro Val Thr His Val Ala Ala Asn Thr Leu
385                 390                 395                 400

Pro His Leu Thr Ile Pro Ala Val Val Thr Val Thr Cys Ser Arg Leu
                405                 410                 415

Phe Ala Val Asn Arg Trp His Asn Thr Val Gly Leu Arg Gly Ala Pro
            420                 425                 430

Gly Ile Leu Leu Gly Ser Ser Pro Pro Ser Ser His 
        435                 440



<210> 1658
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (31)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1658
Met His Ala Gly Arg Pro Asp Leu Ser Phe Pro Leu Ala Val Ala Ala
  1               5                  10                  15

Ser Ala Pro Leu Ser Val Arg Leu Ile His Leu Val Ala Cys Xaa Cys
             20                  25                  30

Gly Leu Phe Ile Leu Lys Cys Ser Val Cys Gln Val Leu His Cys Val
         35                  40                  45

Lys Ile Pro Gln His Val His Ser Ile Ile Asn Gly His Leu Gly Ser
     50                  55                  60

Phe His Ser Leu Ala Val Arg Asn Ser Ala Val Met Asn Met Leu Ala
 65                  70                  75                  80

Pro Val Phe Cys Phe Phe Phe Ile Phe Arg Asp Arg Val Leu Leu Cys
                 85                  90                  95

Xaa Pro Gly Trp Ser Ala Val Val 
            100



<210> 1659
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1659
Met Gly Phe Val Pro Thr Pro Glu Ile Leu Trp Glu Thr Asn Ser Phe
  1               5                  10                  15

Asn Ser Leu Ser Ser Arg His Gln Glu Ser Leu Asn Asn His Gly Leu
             20                  25                  30

Leu Cys Leu Gly Phe Phe Phe Phe Leu Ala Leu Phe Leu Val Phe Val
         35                  40                  45

Cys Val Cys Val Cys Cys Met His Met Arg Pro Arg Leu Thr Gly Gly
     50                  55                  60

Leu Gly Glu Ser Ala Ser Asn Ser Val Asn Val Ile Val Asn Tyr Ile
 65                  70                  75                  80

Ser Tyr Leu Arg Ser His Cys Phe Gln Ile Asn Ser Val Phe His Glu
                 85                  90                  95

Lys Lys Lys Lys Lys Xaa Xaa Cys Gly Arg Gln 
            100                 105



<210> 1660
<211> 155
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1660
Met Gly Glu Arg Thr Leu His Ala Ala Val Pro Thr Pro Gly Tyr Pro
  1               5                  10                  15

Glu Ser Glu Ser Ile Met Met Ala Pro Ile Cys Leu Val Glu Asn Gln
             20                  25                  30

Glu Glu Gln Leu Thr Val Asn Ser Lys Ala Leu Glu Ile Leu Asp Lys
         35                  40                  45

Ile Ser Gln Pro Val Val Val Val Ala Ile Val Gly Leu Tyr Arg Thr
     50                  55                  60

Gly Lys Ser Tyr Leu Met Asn Arg Leu Ala Gly Lys Arg Asn Gly Phe
 65                  70                  75                  80

Pro Leu Gly Ser Thr Val Gln Ser Glu Thr Xaa Gly His Leu Asp Val
                 85                  90                  95

Val Cys Ala Pro Leu Ser Lys Pro Asn Xaa Thr Leu Val Leu Leu Asp
            100                 105                 110

Thr Glu Gly Leu Gly Asp Val Glu Lys Ser Asn Pro Lys Asn Asp Ser
        115                 120                 125

Trp Ile Xaa Ala Leu Ala Val Leu Leu Ser Ser Ser Phe Val Tyr Asn
    130                 135                 140

Ser Val Gly Pro Leu Thr Thr Arg Pro Gly Xaa 
145                 150                 155



<210> 1661
<211> 109
<212> PRT
<213> Homo sapiens

<400> 1661
Met Gln Ser Ser Gly Asp Leu Glu Asn Asp Glu Gln Ala Ala Ser Ala
  1               5                  10                  15

Ile Ser Glu Leu Val Ser Thr Ala Cys Gly Phe Arg Leu His Arg Gly
             20                  25                  30

Met Asn Val Pro Phe Lys Arg Leu Ser Gly Glu Pro Leu Pro Leu Pro
         35                  40                  45

Leu Val Val Val Leu Gly Ala Gly Gly Tyr Phe Gln Gly Leu Leu Gly
     50                  55                  60

Phe Pro Leu Leu Gly Arg Gly Lys Cys Val Ser Pro Pro Val Val Phe
 65                  70                  75                  80

Gly Glu His Thr Leu Leu Val Thr Val Ser Gly Gln Arg Val Phe Val
                 85                  90                  95

Val Lys Lys Gln Asn Arg Gly Arg Glu Pro Ile Asn Phe 
            100                 105



<210> 1662
<211> 100
<212> PRT
<213> Homo sapiens

<400> 1662
Met Tyr Gly His Ile Glu Thr Met Ala Arg Ala Ser Leu Arg Val Gln
  1               5                  10                  15

Ala Lys Trp Met Ala Leu Lys Leu Ser Leu Ser Val Tyr Arg Lys Pro
             20                  25                  30

Cys Arg Arg Asn Tyr Leu Lys Lys Gln Ala Val Lys Arg Lys Leu His
         35                  40                  45

Arg Leu Gln Pro Arg Lys Asn Trp Pro Ile Thr Thr Pro Leu Phe Leu
     50                  55                  60

Val His Leu Pro Ala Leu Ala Thr Cys Pro Val Lys Cys Val Pro Ser
 65                  70                  75                  80

Ser Thr Arg Arg Ala Ala Cys Gly Leu Pro Ala His Tyr Thr Glu Asn
                 85                  90                  95

Trp Arg Arg Leu 
            100



<210> 1663
<211> 203
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1663
Met His Ala Arg Ala Xaa Ala Ser Val Met Asp Ile Cys Arg Ile Arg
  1               5                  10                  15

Leu Phe Glu Arg Pro Pro Gly Gln Val His Gly Ala Xaa Gly Val Phe
             20                  25                  30

Ile Ala Asp Glu Val Gln Val Gly Phe Gly Arg Val Gly Lys His Xaa
         35                  40                  45

Trp Ser Phe Gln Met Tyr Gly Glu Asp Phe Val Xaa Asp Ile Val Thr
     50                  55                  60

Met Gly Lys Pro Met Gly Asn Gly His Pro Val Ala Cys Val Val Thr
 65                  70                  75                  80

Thr Lys Glu Ile Ala Glu Ala Phe Ser Ser Ser Gly Met Glu Tyr Phe
                 85                  90                  95

Asn Thr Tyr Gly Gly Asn Pro Val Ser Cys Ala Val Gly Leu Ala Val
            100                 105                 110

Leu Asp Ile Ile Glu Asn Glu Asp Leu Gln Gly Asn Ala Lys Arg Val
        115                 120                 125

Gly Asn Tyr Leu Thr Glu Leu Leu Lys Lys Gln Lys Ala Lys His Thr
    130                 135                 140

Leu Ile Gly Asp Ile Arg Gly Ile Gly Leu Phe Ile Gly Ile Asp Leu
145                 150                 155                 160

Val Lys Asp His Leu Lys Arg Thr Pro Ala Thr Ala Glu Ala Gln His
                165                 170                 175

Ile Ile Tyr Lys Met Lys Glu Lys Arg Val Leu Leu Ser Ala Asp Gly
            180                 185                 190

Pro His Arg Asn Val Pro Arg Pro Arg Pro Arg 
        195                 200



<210> 1664
<211> 188
<212> PRT
<213> Homo sapiens

<400> 1664
Met Phe Phe Pro Leu Glu Pro Ser Ala Pro Ser Lys Leu His Ser Val
  1               5                  10                  15

Thr Gly Ile Asp Thr Lys Asp Lys Ser Leu Lys Thr Val Ser Ser Gly
             20                  25                  30

Ala Lys Lys Ser Phe Glu Leu Leu Ser Glu Ser Asp Gly Ala Leu Met
         35                  40                  45

Glu His Pro Glu Val Ser Gln Val Arg Arg Lys Thr Val Glu Phe Asn
     50                  55                  60

Leu Thr Asp Met Pro Glu Ile Pro Glu Asn His Leu Lys Glu Pro Leu
 65                  70                  75                  80

Glu Gln Ser Pro Thr Asn Ile His Thr Thr Leu Lys Asp His Met Asp
                 85                  90                  95

Pro Tyr Trp Ala Leu Glu Asn Arg Ser Val Leu His Leu Asn Gln Gly
            100                 105                 110

His Cys Ile Ala Leu Cys Pro Thr Pro Ala Ser Leu Ala Leu Ser Leu
        115                 120                 125

Pro Phe Leu His Asn Phe Leu Gly Phe His His Cys Gln Ser Thr Leu
    130                 135                 140

Asp Leu Arg Pro Ala Leu Ala Trp Gly Ile Tyr Leu Ala Thr Phe Thr
145                 150                 155                 160

Gly Ile Leu Gly Lys Cys Pro Gly Pro Phe Leu Thr Ser Pro Trp Tyr
                165                 170                 175

His Pro Glu Asp Phe Leu Gly Pro Gly Glu Gly Arg 
            180                 185



<210> 1665
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1665
Met Leu Thr Leu Ser Tyr Pro Phe Cys Ala Lys Met Asp Ser Ile Gly
  1               5                  10                  15

Lys Met Ile Pro Gln Leu Leu Ile Leu Trp Leu Tyr Ile Ala Leu Xaa
             20                  25                  30

Thr Leu Lys His Gln Met Glu Leu Asn Thr Tyr Leu Lys Phe Arg Leu
         35                  40                  45

Gly Asn Ile Gly Glu Glu Ala Ser Lys Arg Gly Lys His Leu Leu Ser
     50                  55                  60

Gly Arg Ile Phe Ser Ile Leu Trp Ile Ser Leu Ile Phe Phe Tyr His
 65                  70                  75                  80

Pro Glu Gly Cys Trp Gly Asn Tyr His Phe Ala Thr Phe Xaa Glu Val
                 85                  90                  95

Ile Gln Asp Phe 
            100



<210> 1666
<211> 154
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (149)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1666
Met Trp Arg Gln Arg Gly Arg Val Ile Ser Leu Trp Glu Arg Leu Glu
  1               5                  10                  15

Phe Val Asn Gly Trp Tyr Ile Leu Leu Val Thr Ser Asp Val Leu Thr
             20                  25                  30

Ile Ser Gly Thr Ile Met Lys Ile Gly Ile Glu Ala Lys Asn Leu Ala
         35                  40                  45

Ser Tyr Asp Val Cys Ser Ile Leu Leu Gly Thr Ser Thr Leu Leu Val
     50                  55                  60

Trp Val Gly Val Ile Arg Tyr Leu Thr Phe Phe His Asn Tyr Asn Ile
 65                  70                  75                  80

Leu Ile Ala Thr Leu Arg Val Ala Leu Pro Ser Val Met Arg Phe Cys
                 85                  90                  95

Cys Cys Val Ala Val Ile Xaa Leu Gly Tyr Cys Phe Cys Gly Trp Ile
            100                 105                 110

Val Leu Gly Xaa Tyr His Val Lys Pro Leu His Leu His Gly Ala Gln
        115                 120                 125

Pro Xaa His Arg Xaa His His Arg Xaa Leu Arg His His Gln Ala Ser
    130                 135                 140

Arg Arg Arg Arg Xaa Arg Gly Glu Arg Ala 
145                 150



<210> 1667
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (145)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1667
Met Ile Phe Tyr Ala Asn Asp Thr Gly Ala Gln Gln Phe Glu Lys Trp
  1               5                  10                  15

Trp Asp Lys Ser Arg Thr Val Pro Phe Tyr Leu Val Gly Leu Leu Leu
             20                  25                  30

Pro Leu Leu Asn Phe Lys Ser Pro Ser Phe Phe Ser Lys Phe Xaa Ile
         35                  40                  45

Leu Gly Thr Val Ser Val Xaa Xaa Leu Ile Phe Leu Val Thr Phe Lys
     50                  55                  60

Ala Val Arg Leu Gly Phe His Leu Glu Phe His Trp Phe Ile Pro Thr
 65                  70                  75                  80

Glu Phe Phe Val Pro Glu Ile Arg Phe Gln Phe Pro Gln Leu Thr Gly
                 85                  90                  95

Val Leu Thr Leu Ala Phe Phe Ile His Asn Cys Ile Ile Thr Leu Leu
            100                 105                 110

Glu Glu Gln Gln Glu Thr Arg Lys Thr Met Trp Arg Gly Leu Val Ala
        115                 120                 125

Leu Ala Tyr Met Leu Val Asp Ile Asn Leu Thr Xaa Xaa Trp Glu Ser
    130                 135                 140

Xaa Val Leu 
145



<210> 1668
<211> 131
<212> PRT
<213> Homo sapiens

<400> 1668
Met Ser Phe Ala Glu Ser Gly Trp Arg Ser Ala Leu Arg Arg Arg Gly
  1               5                  10                  15

Pro Gly Thr Pro Gly Pro Val Ala Arg Pro Ser Tyr Ser Ser Phe Thr
             20                  25                  30

Gln Gly Asp Ser Trp Gly Glu Gly Glu Val Asp Glu Glu Glu Gly Cys
         35                  40                  45

Asp Gln Val Ala Arg Asp Leu Arg Ala Glu Phe Ser Ala Gly Ala Trp
     50                  55                  60

Ser Glu Pro Arg Lys Arg Ser Val Leu Pro Pro Asp Gly Asn Gly Ser
 65                  70                  75                  80

Pro Val Leu Pro Asp Lys Arg Asn Gly Ile Phe Pro Ala Ala Ala Gly
                 85                  90                  95

Ser Arg Ala Gln Pro Arg Arg Trp Pro Val Gln Val Leu Ser Ile Leu
            100                 105                 110

Cys Ser Leu Leu Phe Ala Ile Leu Leu Ala Phe Leu Leu Ala Ser Leu
        115                 120                 125

Leu Asp Arg 
    130



<210> 1669
<211> 511
<212> PRT
<213> Homo sapiens

<400> 1669
Met Ala Val Val Ser Lys Gln Val Asn Met Glu Leu Ala Lys Ile Lys
  1               5                  10                  15

Gln Lys Cys Pro Leu Tyr Glu Ala Asn Gly Gln Ala Val Pro Lys Glu
             20                  25                  30

Lys Asp Glu Met Val Glu Gln Glu Phe Asn Arg Leu Leu Glu Ala Thr
         35                  40                  45

Ser Tyr Leu Ser His Gln Leu Asp Phe Asn Val Leu Asn Asn Lys Pro
     50                  55                  60

Val Ser Leu Gly Gln Ala Leu Glu Val Val Ile Gln Leu Gln Glu Lys
 65                  70                  75                  80

His Val Lys Asp Glu Gln Ile Glu His Trp Lys Lys Ile Val Lys Thr
                 85                  90                  95

Gln Glu Glu Leu Lys Glu Leu Leu Asn Lys Met Val Asn Leu Lys Glu
            100                 105                 110

Lys Ile Lys Glu Leu His Gln Gln Tyr Lys Glu Ala Ser Glu Val Lys
        115                 120                 125

Pro Pro Arg Asp Ile Thr Ala Glu Phe Leu Val Lys Ser Lys His Arg
    130                 135                 140

Asp Leu Thr Ala Leu Cys Lys Glu Tyr Asp Glu Leu Ala Glu Thr Gln
145                 150                 155                 160

Gly Lys Leu Glu Glu Lys Leu Gln Glu Leu Glu Ala Asn Pro Pro Ser
                165                 170                 175

Asp Val Tyr Leu Ser Ser Arg Asp Arg Gln Ile Leu Asp Trp His Phe
            180                 185                 190

Ala Asn Leu Glu Phe Ala Asn Ala Thr Pro Leu Ser Thr Leu Ser Leu
        195                 200                 205

Lys His Trp Asp Gln Asp Asp Asp Phe Glu Phe Thr Gly Ser His Leu
    210                 215                 220

Thr Val Arg Asn Gly Tyr Ser Cys Val Pro Val Ala Leu Ala Glu Gly
225                 230                 235                 240

Leu Asp Ile Lys Leu Asn Thr Ala Val Arg Gln Val Arg Tyr Thr Ala
                245                 250                 255

Ser Gly Cys Glu Val Ile Ala Val Asn Thr Arg Ser Thr Ser Gln Thr
            260                 265                 270

Phe Ile Tyr Lys Cys Asp Ala Val Leu Cys Thr Leu Pro Leu Gly Val
        275                 280                 285

Leu Lys Gln Gln Pro Pro Ala Val Gln Phe Val Pro Pro Leu Pro Glu
    290                 295                 300

Trp Lys Thr Ser Ala Val Gln Arg Met Gly Phe Gly Asn Leu Asn Lys
305                 310                 315                 320

Val Val Leu Cys Phe Asp Arg Val Phe Trp Asp Pro Ser Val Asn Leu
                325                 330                 335

Phe Gly His Val Gly Ser Thr Thr Ala Ser Arg Gly Glu Leu Phe Leu
            340                 345                 350

Phe Trp Asn Leu Tyr Lys Ala Pro Ile Leu Leu Ala Leu Val Ala Gly
        355                 360                 365

Glu Ala Ala Gly Ile Met Glu Asn Ile Ser Asp Asp Val Ile Val Gly
    370                 375                 380

Arg Cys Leu Ala Ile Leu Lys Gly Ile Phe Gly Ser Ser Ala Val Pro
385                 390                 395                 400

Gln Pro Lys Glu Thr Val Val Ser Arg Trp Arg Ala Asp Pro Trp Ala
                405                 410                 415

Arg Gly Ser Tyr Ser Tyr Val Ala Ala Gly Ser Ser Gly Asn Asp Tyr
            420                 425                 430

Asp Leu Met Ala Gln Pro Ile Thr Pro Gly Pro Ser Ile Pro Gly Ala
        435                 440                 445

Pro Gln Pro Ile Pro Arg Leu Phe Phe Ala Gly Glu His Thr Ile Arg
    450                 455                 460

Asn Tyr Pro Ala Thr Val His Gly Ala Leu Leu Ser Gly Leu Arg Glu
465                 470                 475                 480

Ala Gly Arg Ile Ala Asp Gln Phe Leu Gly Ala Met Tyr Thr Leu Pro
                485                 490                 495

Arg Gln Ala Thr Pro Gly Val Pro Ala Gln Gln Ser Pro Ser Met 
            500                 505                 510



<210> 1670
<211> 146
<212> PRT
<213> Homo sapiens

<400> 1670
Met Leu Gln Phe Phe Val His Phe Leu Ser Leu Val Tyr Leu Tyr Arg
  1               5                  10                  15

Glu Ala Gln Ala Arg Ser Pro Glu Lys Gln Glu Gln Phe Val Asp Leu
             20                  25                  30

Tyr Lys Glu Phe Glu Pro Ser Leu Val Asn Ser Thr Val Tyr Ile Met
         35                  40                  45

Ala Met Ala Met Gln Met Ala Thr Phe Ala Ile Asn Tyr Lys Gly Pro
     50                  55                  60

Pro Phe Met Glu Ser Leu Pro Glu Asn Lys Pro Leu Val Trp Ser Leu
 65                  70                  75                  80

Ala Val Ser Leu Leu Ala Ile Ile Gly Leu Leu Leu Gly Ser Ser Pro
                 85                  90                  95

Asp Phe Asn Ser Gln Phe Gly Leu Val Asp Ile Pro Val Glu Phe Lys
            100                 105                 110

Leu Val Ile Ala Gln Val Leu Leu Leu Asp Phe Cys Leu Ala Leu Leu
        115                 120                 125

Ala Asp Arg Val Leu Gln Phe Phe Leu Gly Thr Pro Lys Leu Lys Val
    130                 135                 140

Pro Ser 
145



<210> 1671
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1671
Met Phe Cys Gln Val Lys Glu Ile Phe Tyr Ile Ser Ser Phe Leu Tyr
  1               5                  10                  15

Thr Val Asn Tyr Ile Trp Tyr Leu Tyr Thr Glu Leu Arg Met Lys His
             20                  25                  30

Thr Gln Ser Gly Gln Ser Thr Ser Pro Leu Val Ile Asp Tyr Thr Cys
         35                  40                  45

Arg Val Xaa Gln Met Xaa Phe Val Phe Ser Ser Leu Ile Pro Leu Leu
     50                  55                  60

Leu Met Thr Pro Val Phe Cys Leu Gly Asn Thr Ser Glu Cys Phe Gln
 65                  70                  75                  80

Asn Phe Ser Gln Ser His Lys Ser Tyr Leu Ser Glu Pro Arg His Cys
                 85                  90                  95

Ile Arg Ser Leu 
            100



<210> 1672
<211> 150
<212> PRT
<213> Homo sapiens

<400> 1672
Met Lys Arg Val Arg Thr Glu Gln Ile Gln Met Ala Val Ser Cys Tyr
  1               5                  10                  15

Leu Lys Arg Arg Gln Tyr Val Asp Ser Asp Gly Pro Leu Lys Gln Gly
             20                  25                  30

Leu Arg Leu Ser Gln Thr Ala Glu Glu Met Ala Ala Asn Leu Thr Val
         35                  40                  45

Gln Ser Glu Ser Gly Cys Ala Asn Ile Val Ser Ala Ala Pro Cys Gln
     50                  55                  60

Ala Glu Pro Gln Gln Tyr Glu Val Gln Phe Gly Arg Leu Arg Asn Phe
 65                  70                  75                  80

Leu Thr Asp Ser Asp Ser Gln His Ser His Glu Val Met Pro Leu Leu
                 85                  90                  95

Tyr Pro Leu Phe Val Tyr Leu His Leu Asn Leu Val Gln Asn Ser Pro
            100                 105                 110

Lys Ser Thr Val Glu Ser Phe Tyr Ser Arg Phe His Gly Met Phe Leu
        115                 120                 125

Gln Asn Ala Ser Gln Lys Asp Val Ile Glu Gln Leu Gln Thr Leu Lys
    130                 135                 140

His Pro Asp Ile Tyr Leu 
145                 150



<210> 1673
<211> 193
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (179)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (185)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1673
Met Leu Glu Ser Ile Ile Arg Gly Leu Tyr His Leu Ala Arg Thr Glu
  1               5                  10                  15

Val Val Cys Glu Ser Leu Lys Ala Leu Lys Lys Ile Leu Glu Leu Leu
             20                  25                  30

Thr Asp Arg Asp Val Ser Phe Tyr Phe Lys Glu Ile Val Leu Gln Thr
         35                  40                  45

Arg Thr Phe Phe Glu Asp Glu Gln Asp Asp Val Arg Leu Thr Ala Ile
     50                  55                  60

Phe Leu Phe Glu Asp Leu Ala Pro Leu Thr Gly Arg Arg Trp Lys Ile
 65                  70                  75                  80

Phe Phe Ala Glu Glu Ile Lys Lys Ser Leu Ile Ser Phe Leu Leu His
                 85                  90                  95

Leu Trp Asp Pro Asn Pro Lys Ile Gly Val Ala Cys Arg Asp Val Leu
            100                 105                 110

Met Val Cys Ile Pro Phe Leu Gly Leu Gln Glu Leu Tyr Gly Val Leu
        115                 120                 125

Asp Arg Leu Leu Asp Gln Asp Leu Pro Arg Ala Arg Asp Phe Tyr Arg
    130                 135                 140

Gln Phe Cys Val Lys Leu Ala Lys Lys Asn Gln Glu Ile Leu Xaa Ile
145                 150                 155                 160

Phe Thr His Thr Ser Xaa Pro Ser Ser Pro Ser Thr Leu Gly Arg Gly
                165                 170                 175

Ser Gly Xaa Ala Ser Cys Gln Asn Xaa Arg Xaa Pro Leu Phe Leu Asn
            180                 185                 190

Leu 




<210> 1674
<211> 127
<212> PRT
<213> Homo sapiens

<400> 1674
Met Asp Trp Gly Thr Leu His Thr Phe Ile Gly Gly Val Asn Lys His
  1               5                  10                  15

Ser Thr Ser Ile Gly Lys Val Trp Ile Thr Val Ile Phe Ile Phe Arg
             20                  25                  30

Val Met Ile Leu Val Val Ala Ala Gln Glu Val Trp Gly Asp Glu Gln
         35                  40                  45

Glu Asp Phe Val Cys Asn Thr Leu Gln Pro Gly Cys Lys Asn Val Cys
     50                  55                  60

Tyr Asp His Phe Phe Pro Val Ser His Ile Arg Leu Trp Ala Leu Gln
 65                  70                  75                  80

Leu Ile Phe Val Ser Thr Pro Ala Leu Leu Val Ala Met His Val Ala
                 85                  90                  95

Tyr Tyr Arg His Glu Thr Thr Arg Lys Phe Arg Arg Gly Glu Lys Arg
            100                 105                 110

Asn Asp Phe Lys Asp Ile Glu Asp Ile Lys Ser Arg Arg Phe Gly 
        115                 120                 125



<210> 1675
<211> 162
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1675
Met Cys Asn Val Met Met Gln Leu Arg Lys Met Ala Asn His Pro Leu
  1               5                  10                  15

Leu His Arg Gln Tyr Tyr Thr Ala Glu Lys Leu Lys Glu Met Ser Gln
             20                  25                  30

Leu Met Leu Lys Glu Pro Thr His Cys Glu Ala Asn Pro Asp Leu Ile
         35                  40                  45

Phe Glu Asp Met Glu Val Met Thr Asp Phe Glu Leu His Val Leu Cys
     50                  55                  60

Lys Gln Tyr Arg His Ile Asn Asn Phe Gln Leu Asp Met Asp Leu Ile
 65                  70                  75                  80

Leu Asp Ser Gly Lys Phe Arg Val Leu Gly Cys Ile Leu Ser Glu Leu
                 85                  90                  95

Lys Gln Lys Gly Asp Arg Val Val Leu Phe Ser Gln Phe Thr Met Xaa
            100                 105                 110

Leu Xaa Ile Leu Glu Val Leu Leu Lys His His Gln His Arg Tyr Xaa
        115                 120                 125

Arg Leu Asp Gly Lys Thr Gln Xaa Ser Glu Gly Ile Xaa Leu Ile Asp
    130                 135                 140

Glu Phe Asn Thr Asp Xaa Tyr Leu Trp Phe Leu Leu Ser Gln Lys Leu
145                 150                 155                 160

Val Asp 




<210> 1676
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1676
Met Pro Asn Asn Ile Glu Lys Asn Phe Ser Arg Val Gly Thr Leu Val
  1               5                  10                  15

Val Leu Ile Ser Val Thr Ile Leu Tyr Ala Gly Ile Asn Phe Ser Cys
             20                  25                  30

Trp Ser Ala Leu Gln Leu Arg Xaa Ala Asp Arg Asp Leu Val Asp Lys
         35                  40                  45

Gly Gln Asn Trp Gly His Met Gly Leu His Tyr Ser Val Lys Leu Val
     50                  55                  60

Glu Asn Val Ile Met Val Leu Val Phe Lys Phe Xaa Gly Val Lys Val
 65                  70                  75                  80

Xaa Leu Asn Tyr Cys His Xaa Leu Xaa Ala Leu Gln Leu Ile Ile Ala
                 85                  90                  95

Tyr Leu Ile Ser Ile Gly Phe Met Leu Leu Phe Phe Gln Tyr Leu His
            100                 105                 110

Pro Leu Arg Ser Leu Phe Thr His Asn Val Val Asp Tyr Leu His Cys
        115                 120                 125

Val Cys Cys 
    130



<210> 1677
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1677
Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu
  1               5                  10                  15

Pro Val Trp Glu Arg Pro Trp Ser Val Xaa Glu Ile Arg Arg Ser Ser
             20                  25                  30

Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln
         35                  40                  45

Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln
     50                  55                  60

Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His
 65                  70                  75                  80

Asn Xaa Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu
                 85                  90                  95

Asn Val Ser Tyr Leu Ser Tyr Ile Ile Ile Pro Phe Leu Gly Val Gly
            100                 105                 110

Asp Ile Val Ile Leu Asn Asn Leu Leu Leu Gly Ser Leu Leu Asn Phe
        115                 120                 125

Gly Gly Ser Val Val Leu Gly Asn Cys Ser Phe Phe Leu Trp Asp 
    130                 135                 140



<210> 1678
<211> 107
<212> PRT
<213> Homo sapiens

<400> 1678
Met Lys Arg Glu Thr Ile Phe Ile Phe Leu Asp Ser Leu Phe His Asn
  1               5                  10                  15

Phe Ser Phe His Ala Ser Ile Tyr Ile Thr Leu Asn Phe Leu Ser Pro
             20                  25                  30

Gln Ile Lys Ile Leu Phe Cys Pro Ala Asn Lys Lys Thr Ile Pro Tyr
         35                  40                  45

Cys Leu Asn Val Ile Gln Ser Ser Leu Tyr Tyr Ser Thr Leu Cys Phe
     50                  55                  60

Phe Leu Phe His Phe Val Lys Asn Ser Met Leu Val Leu Leu Asp Asp
 65                  70                  75                  80

Cys Leu Phe Met Cys Asn Ile Asn Pro Thr Tyr Ser Asn Asp Asn Phe
                 85                  90                  95

Phe Asn Pro Ser Gly Ser Tyr Ile Ile Phe Pro 
            100                 105



<210> 1679
<211> 205
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1679
Met Leu Leu Pro Trp Gln Thr Val Arg Leu Ile His Met Met Arg Val
  1               5                  10                  15

Leu Leu Ile Lys Leu Val Ala Pro Phe Ile Ile Phe Arg Ala Pro Arg
             20                  25                  30

Arg Ile Ala Val Phe Ala Asp Lys Arg Gln Arg Gln Ser Pro Val Val
         35                  40                  45

Ala Val Ile Lys Met Xaa Phe Ser Arg Arg Cys Val Phe Arg Leu His
     50                  55                  60

Leu Ser Gly Gln Leu Leu His Arg Gln Pro Ala Leu Arg Lys Pro Arg
 65                  70                  75                  80

Pro Ala Phe Thr Ala His Ala Val Cys Pro Asp Phe Phe Leu Gln Pro
                 85                  90                  95

Val Gln Gln Pro Xaa Gln Phe Ser Arg Glu His His Ala Val Ala Val
            100                 105                 110

Leu Thr Pro Phe Leu Leu Glu Arg Leu Cys Gln Ala Ala Pro Leu Arg
        115                 120                 125

Phe Phe Pro Leu Ala Val Leu Cys Leu Asp Arg Met Asn Gly Val Asn
    130                 135                 140

Phe Pro Ala Arg Ile Pro Ser Gly Tyr Cys Gly Val Ser Leu His Arg
145                 150                 155                 160

Leu Gln Xaa Val Ser Val His Pro Tyr His Val Thr Pro Val Tyr Arg
                165                 170                 175

Lys Arg Asn Pro Pro Arg Gln Val Thr Leu Pro Pro Pro Lys Pro Phe
            180                 185                 190

Cys His Ser Pro Pro Asn Arg Val Leu Lys Gly Ser Gly 
        195                 200                 205



<210> 1680
<211> 104
<212> PRT
<213> Homo sapiens

<400> 1680
Met Val Val Ser His Tyr Ala Arg Pro Asp Leu Pro Leu Leu Met Val
  1               5                  10                  15

Ile Ser Cys Glu Ser Phe Phe Leu Pro Leu His Ser Phe Tyr Ser Val
             20                  25                  30

Tyr Ser Pro Met Pro His Pro Lys Ser Cys Thr Val Asn Trp Pro Val
         35                  40                  45

Lys Gly Thr Pro Thr Phe Lys Gln Gly Arg Gln Asp Thr Thr Gly Arg
     50                  55                  60

Arg Leu Ile Ala Gln Thr Leu Asp Cys Ser Gly Trp Asp Gln Ile Leu
 65                  70                  75                  80

Ala Pro Leu Leu Ala Ser Cys Val Ala Leu Gly Lys Leu Leu Asn Leu
                 85                  90                  95

Ser Gly Pro Gln Phe Leu Pro Leu 
            100



<210> 1681
<211> 126
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1681
Met Ile Leu Leu Leu Ile Val Leu His Thr Ser Tyr Met Ile Tyr Ser
  1               5                  10                  15

Leu Ala Pro Gln Tyr Val Met Tyr Gly Ser Gln Asn Tyr Leu Ile Glu
             20                  25                  30

Thr Asn Ile Thr Ser Asp Asn His Lys Gly Asn Ser Thr Leu Ser Val
         35                  40                  45

Pro Lys Arg Cys Asp Ala Xaa Ala Pro Glu Asp Gln Cys Thr Val Thr
     50                  55                  60

Arg Thr Tyr Leu Phe Leu His Lys Phe Trp Phe Phe Ser Ala Ala Tyr
 65                  70                  75                  80

Tyr Phe Gly Asn Trp Ala Phe Leu Gly Val Phe Leu Ile Gly Leu Ile
                 85                  90                  95

Val Ser Cys Cys Lys Gly Lys Lys Ser Val Ile Glu Gly Val Asp Glu
            100                 105                 110

Asp Ser Asp Ile Ser Asp Asp Glu Pro Ser Val Tyr Ser Ala 
        115                 120                 125



<210> 1682
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1682
Met Glu Glu Lys Tyr Gly Gly Asp Val Leu Ala Gly Pro Gly Gly Gly
  1               5                  10                  15

Gly Gly Leu Gly Pro Val Asp Val Pro Ser Ala Arg Leu Thr Lys Tyr
             20                  25                  30

Ile Val Leu Leu Cys Phe Thr Lys Phe Leu Lys Ala Val Gly Leu Phe
         35                  40                  45

Glu Ser Tyr Asp Leu Leu Lys Ala Val His Ile Val Gln Phe Ile Phe
     50                  55                  60

Ile Leu Lys Leu Gly Thr Ala Phe Phe Met Val Leu Phe Gln Lys Pro
 65                  70                  75                  80

Phe Ser Ser Gly Lys Thr Ile Thr Lys His Gln Ile Ile Gly Ser Leu
                 85                  90                  95

Lys Ile Pro Gly Arg Lys Glu Phe Xaa Asp Lys Lys Leu Asn Asp Pro
            100                 105                 110

Arg Lys Leu Val Gly Asn 
        115



<210> 1683
<211> 261
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (241)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1683
Met Leu Thr Pro Tyr Val Ala Arg Lys Leu Ala Val Ala Ser Val Thr
  1               5                  10                  15

Glu Ile Leu Lys Met Leu Asn Ser Asn Thr Glu Ser Pro Tyr Leu Ile
             20                  25                  30

Trp Asn Asn Ser Thr Arg Ala Glu Leu Leu Glu Phe Leu Glu Ser Gln
         35                  40                  45

Gln Glu Asn Met Ile Lys Lys Gly Asp Cys Asp Lys Thr Tyr Gly Ser
     50                  55                  60

Glu Phe Val Tyr Ser Asp His Ala Lys Glu Leu Ile Val Gly Glu Ile
 65                  70                  75                  80

Phe Val Arg Val Tyr Asn Glu Val Pro Thr Phe Gln Leu Glu Val Pro
                 85                  90                  95

Lys Ala Phe Ala Ala Ser Leu Leu Asp Tyr Ile Gly Ser Xaa Ala Gln
            100                 105                 110

Tyr Leu His Thr Phe Met Ala Ile Thr His Ala Ala Lys Val Glu Ser
        115                 120                 125

Glu Gln His Gly Asp Arg Leu Pro Arg Val Glu Met Ala Leu Glu Ala
    130                 135                 140

Leu Arg Asn Val Ile Lys Tyr Asn Pro Gly Ser Glu Ser Glu Cys Ile
145                 150                 155                 160

Gly His Phe Lys Leu Ile Phe Ser Leu Leu Arg Val His Gly Ala Gly
                165                 170                 175

Gln Val Gln Gln Leu Ala Leu Glu Val Val Asn Ile Val Thr Ser Asn
            180                 185                 190

Gln Asp Cys Val Asn Asn Ile Ala Glu Ser Met Gly Phe Val Gln Phe
        195                 200                 205

Ile Gly Ser Ser Thr Phe Ile Ala Ile Lys Ser Val Ser Leu Val Leu
    210                 215                 220

Gly Asn Ser Leu Cys Phe Gly His Pro Ser Thr Lys Ile Asn Gln Arg
225                 230                 235                 240

Xaa Asn Gly Lys Gly Cys Phe Asp Ser Ile Tyr Trp Ile Cys Ser Ala
                245                 250                 255

Ile Gln His Ile His 
            260



<210> 1684
<211> 103
<212> PRT
<213> Homo sapiens

<400> 1684
Met Pro Pro Pro Gln Pro Met Glu Leu Leu Trp Leu Ser Ser Leu Ser
  1               5                  10                  15

Arg Thr Val Glu Lys Gly Arg Trp Gly Pro Ser Pro Asn Ser Thr Ala
             20                  25                  30

Ser Ser Ala Val Cys Pro Gln Pro Arg Arg Ala Gly Lys Ala Ser Gly
         35                  40                  45

Leu Leu His Leu Val Leu Val Thr Pro Gly Val Cys Val Gln Ile Thr
     50                  55                  60

Thr Ser Leu Phe Gly Ser Leu Leu Arg Ser Arg Phe Pro Asp Gly Ser
 65                  70                  75                  80

Ile Thr Ala Leu Ser Tyr Gln Ala Ala Val Phe His Ser Trp Trp Ser
                 85                  90                  95

Gln Pro Gly Lys Leu Leu Ser 
            100



<210> 1685
<211> 270
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (219)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (261)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (263)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (266)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1685
Met Trp Arg Lys Ser Tyr Arg Leu Pro Asp Tyr Asn Pro Arg Tyr Lys
  1               5                  10                  15

Ile Asp Gly Ser Leu Glu Val Pro Leu Glu Arg Ala Lys Asp Gln Leu
             20                  25                  30

Glu Lys His Thr Arg Tyr Trp Pro Met Ile Ile Ser Gln Thr Thr Ile
         35                  40                  45

Phe Asn Met Gln Ala Val Val Pro Leu Ala Ser Val Ile Val Lys Xaa
     50                  55                  60

Ser Leu Thr Glu Glu Asp Val Leu Asn Cys Gln Lys Thr Ile Tyr Asn
 65                  70                  75                  80

Leu Val Asp Met Glu Arg Lys Asn Asp Pro Leu Pro Ile Ser Thr Val
                 85                  90                  95

Gly Thr Arg Gly Lys Gly Pro Lys Arg Asp Glu Gln Tyr Arg Ile Met
            100                 105                 110

Trp Asn Glu Leu Glu Thr Leu Val Arg Ala His Ile Asn Asn Ser Glu
        115                 120                 125

Lys His Gln Arg Val Leu Glu Cys Leu Met Ala Cys Arg Ser Lys Pro
    130                 135                 140

Pro Glu Glu Glu Glu Arg Lys Lys Arg Gly Arg Lys Arg Glu Asp Lys
145                 150                 155                 160

Glu Asp Lys Ser Glu Lys Ala Val Lys Asp Tyr Glu Gln Glu Lys Ser
                165                 170                 175

Trp Gln Asp Ser Glu Arg Leu Lys Gly Ile Leu Glu Arg Gly Lys Glu
            180                 185                 190

Glu Leu Ala Glu Ala Glu Ile Ile Lys Asp Ser Pro Asp Ser Pro Glu
        195                 200                 205

Pro Pro Asn Lys Lys Pro Leu Val Glu Met Xaa Glu Thr Pro Gln Val
    210                 215                 220

Glu Lys Ser Lys Gly Pro Val Ser Leu Leu Ser Leu Trp Ser Asn Arg
225                 230                 235                 240

Ser Ile Leu Pro Ile Pro Glu Asn Ile Arg Asp Leu Leu Asp Val Leu
                245                 250                 255

Asn Ser Val Asn Xaa Gln Xaa Leu Asn Xaa Ile Gln His Leu 
            260                 265                 270



<210> 1686
<211> 197
<212> PRT
<213> Homo sapiens

<400> 1686
Met Glu Ser Val Phe Asp Tyr Ser Ile Asn Ser Val His Asp Glu Lys
  1               5                  10                  15

Met Glu Glu Gln Thr Glu Ile Leu Gln Asn Gly Phe Asn Pro Glu Glu
             20                  25                  30

Asp Lys Cys Asn Asn Cys Asp Gln Glu Leu Asn Lys Lys Pro Gln Asp
         35                  40                  45

Glu Thr Lys Glu Ser Thr Ser Cys Pro Val Val Gln Lys Arg Ala Ala
     50                  55                  60

Leu Leu Asn Ala Ile Leu His Ser Ala Tyr Ser Glu Thr Phe Leu Leu
 65                  70                  75                  80

Pro His Leu Lys Asp Ile Pro Ala Gln His Ile Thr Leu Phe Leu Lys
                 85                  90                  95

Tyr Leu Tyr Phe Leu Tyr Leu Lys Cys Ser Glu Asn Ala Thr Met Thr
            100                 105                 110

Leu Pro Gly Ile His Pro Pro Thr Leu Asn Gln Ile Met Asp Trp Ile
        115                 120                 125

Cys Leu Leu Leu Asp Ala Asn Phe Thr Val Val Val Met Met Pro Glu
    130                 135                 140

Ala Lys Arg Leu Leu Ile Asn Leu Tyr Lys Leu Val Lys Ser Gln Ile
145                 150                 155                 160

Ser Val Tyr Ser Glu Leu Asn Lys Ile Glu Val Ser Phe Arg Glu Leu
                165                 170                 175

Gln Lys Leu Asn Gln Glu Lys Asn Asn Arg Gly Leu Tyr Ser Ile Glu
            180                 185                 190

Val Leu Glu Leu Phe 
        195



<210> 1687
<211> 339
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1687
Met Leu His Gly Lys Ser Leu Thr Val Ile Pro Tyr Lys Cys Glu Val
  1               5                  10                  15

Ser Ser Leu Ala Gly Ala Leu Gly Lys Leu Lys His Ser Gln Asp Pro
             20                  25                  30

Gly Thr His Val Val Ser His Phe Val Asn Trp Glu Thr Pro Gln Gly
         35                  40                  45

Cys Gly Leu Gly Phe Gln Asn Ser Glu Gln Ser Arg Arg Ile Leu Arg
     50                  55                  60

Arg Arg Lys Ile Glu Val Ser Leu Gln Pro Glu Val Pro Pro Ser Lys
 65                  70                  75                  80

Gln Leu Leu Ser Thr Ile Met Lys Asp Ser Glu Lys His Ile Glu Val
                 85                  90                  95

Glu Val Arg Lys Phe Leu Ala Leu Lys Gln Thr Pro Asp Phe His Thr
            100                 105                 110

Val Ile Gly Asp Thr Val Thr Gly Leu Leu Glu Arg Cys Lys Ala Glu
        115                 120                 125

Pro Ser Phe Tyr Pro Arg Asn Cys Leu Met Gln Leu Ile Xaa Thr His
    130                 135                 140

Val Leu Ser Tyr Ser Leu Cys Pro Asp Leu Met Glu Ile Ala Leu Lys
145                 150                 155                 160

Lys Lys Asp Val Gln Leu Leu Gln Leu Cys Leu Gln Gln Phe Pro Asp
                165                 170                 175

Ile Pro Glu Ser Val Thr Cys Ala Cys Leu Lys Ile Phe Leu Ser Ile
            180                 185                 190

Gly Asp Asp Ser Leu Gln Glu Thr Asp Val Asn Met Glu Ser Val Phe
        195                 200                 205

Asp Tyr Ser Ile Asn Ser Val His Asp Glu Lys Met Glu Glu Gln Thr
    210                 215                 220

Glu Ile Leu Gln Asn Gly Phe Asn Pro Glu Glu Asp Lys Cys Asn Asn
225                 230                 235                 240

Cys Asp Gln Glu Leu Asn Lys Lys Pro Gln Asp Glu Thr Lys Glu Ser
                245                 250                 255

Thr Ser Cys Pro Val Val Gln Lys Arg Ala Ala Leu Leu Asn Ala Ile
            260                 265                 270

Leu His Ser Ala Tyr Ser Glu Thr Phe Leu Leu Pro His Leu Lys Asp
        275                 280                 285

Ile Pro Ala Gln His Ile Thr Leu Phe Leu Lys Tyr Leu Tyr Phe Leu
    290                 295                 300

Tyr Leu Lys Ser Ser Leu Ile Leu Leu Leu Ala Pro Ile Ser Asn Pro
305                 310                 315                 320

Leu Ala Asn Leu Val Asp Pro Thr Phe Thr Ile Tyr Leu Lys Leu Thr
                325                 330                 335

Thr Ser Phe 




<210> 1688
<211> 121
<212> PRT
<213> Homo sapiens

<400> 1688
Met Lys Thr Ile Ser Val Val Gly Ile Glu Leu Cys Pro Pro Gly Lys
  1               5                  10                  15

Arg Phe Met Ile Thr Met Val Ala Ser Phe Val Ala Met Ala Gly Gln
             20                  25                  30

Phe Leu Met Pro Gly Leu Ala Ala Leu Cys Arg Asp Trp Gln Val Leu
         35                  40                  45

Gln Ala Leu Ile Ile Cys Pro Phe Leu Leu Met Leu Leu Tyr Trp Ser
     50                  55                  60

Ile Phe Pro Glu Ser Leu Arg Trp Leu Met Ala Thr Gln Gln Phe Glu
 65                  70                  75                  80

Ser Ala Lys Arg Leu Ile Leu His Phe Thr Gln Lys Asn Arg Met Asn
                 85                  90                  95

Pro Glu Gly Asp Ile Lys Gly Val Ile Pro Glu Leu Glu Lys Glu Leu
            100                 105                 110

Ser Arg Arg Pro Lys Lys Ser Ala Ser 
        115                 120



<210> 1689
<211> 241
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1689
Met Phe Tyr Ser Gly Leu Leu Thr Glu Gly Gly Arg Lys Glu Thr Asp
  1               5                  10                  15

Met Arg Glu Ala Ala Ser Leu Arg Gln Gln Arg Arg Met Lys Gln Ala
             20                  25                  30

Val Gln Phe Ile His Lys Asp Ser Ala Asp Leu Leu Pro Leu Asp Gly
         35                  40                  45

Leu Lys Lys Leu Gly Ser Ser Lys Asp Met Gln Pro His Asn Ile Leu
     50                  55                  60

Gln Arg Arg Leu Met Glu Thr Asn Leu Ser Lys Leu Arg Ser Gly Pro
 65                  70                  75                  80

Arg Val Pro Trp Ala Ser Lys Thr Asn Lys Leu Asn Gln Ala Lys Ser
                 85                  90                  95

Glu Gly Leu Lys Lys Ser Glu Glu Asp Asp Met Ile Leu Val Ser Cys
            100                 105                 110

Gln Cys Ala Gly Lys Asp Val Lys Ala Leu Val Asp Thr Gly Cys Leu
        115                 120                 125

Tyr Asn Leu Ile Ser Leu Ala Cys Val Asp Arg Leu Gly Leu Lys Xaa
    130                 135                 140

His Val Lys Ser His Lys His Glu Gly Glu Lys Leu Ser Leu Pro Arg
145                 150                 155                 160

His Leu Lys Val Val Gly Gln Ile Glu His Leu Val Ile Thr Leu Gly
                165                 170                 175

Ser Leu Arg Leu Asp Cys Pro Ala Ala Val Val Asp Asp Asn Glu Lys
            180                 185                 190

Asn Leu Ser Leu Gly Leu Gln Thr Leu Arg Ser Leu Lys Cys Ile Ile
        195                 200                 205

Asn Leu Asp Lys His Arg Leu Ile Met Gly Lys Thr Asp Lys Glu Glu
    210                 215                 220

Ile Pro Phe Val Glu Thr Val Ser Leu Asn Glu Asp Asn Thr Ser Glu
225                 230                 235                 240

Ala 




<210> 1690
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1690
Met Arg Leu Ser Thr Arg Thr Val Pro Arg Val Ser Ile Ile Tyr Arg
  1               5                  10                  15

His Leu Ser Ser Ile Cys Thr Pro Lys Val Ser Phe Leu Gly Trp His
             20                  25                  30

Ala Gly Lys Phe Ile Cys Arg Ser Arg Arg Val Val Lys Cys Ala Cys
         35                  40                  45

Gly His Ala Asn Thr Ser Phe Cys Phe Thr Gly Ser Leu Leu Pro Pro
     50                  55                  60

Asn Gly Gly Phe Asp Thr Val Thr Ile Tyr Leu Val Ser Cys Cys Ile
 65                  70                  75                  80

Tyr Val Xaa Val Cys His Ile Ser Leu Thr Lys Val Phe Asp Ile Thr
                 85                  90                  95

Ser Leu Val Ile Leu Ser Xaa Xaa Met Gly Thr Leu Lys Glu Cys Thr
            100                 105                 110

Tyr Asp Tyr Lys Ser Cys 
        115



<210> 1691
<211> 102
<212> PRT
<213> Homo sapiens

<400> 1691
Met Trp Thr Glu Ile Phe Ile Phe Cys Leu Arg Ile Tyr Glu Val Tyr
  1               5                  10                  15

His Ile Arg Gly Leu Lys Gln Gly Val Tyr Phe Val Ile Leu Lys Leu
             20                  25                  30

Phe Cys Ile Trp Thr Asn Thr Lys Tyr Pro Ser Gly Leu Phe Phe Phe
         35                  40                  45

Phe Leu Asn Leu Cys Ile His Leu Ile Leu Leu Arg Ile Pro Ser Lys
     50                  55                  60

Gln Lys Asn Leu Leu Cys His Leu His Tyr Ser Asn Tyr Arg Leu Lys
 65                  70                  75                  80

Lys Tyr Gly Gln Phe Leu Lys Lys Phe Arg Leu Cys Phe Pro Trp Lys
                 85                  90                  95

Asp Lys Ser Asp Cys Ser 
            100



<210> 1692
<211> 557
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (472)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1692
Met Glu Arg Leu Glu Lys Val Asn Ser Phe Gln Glu Phe Val Gln Ile
  1               5                  10                  15

Phe Ser Gln Phe Gly Asn Glu Met Val Glu Phe Ala His Leu Ser Gly
             20                  25                  30

Asp Arg Gln Asn Asp Leu Lys Asp Glu Lys Lys Lys Ala Lys Met Ala
         35                  40                  45

Ala Ala Arg Ala Val Leu Glu Lys Cys Thr Met Met Leu Leu Thr Ala
     50                  55                  60

Ser Lys Thr Cys Leu Arg His Pro Asn Cys Glu Ser Ala His Lys Asn
 65                  70                  75                  80

Lys Glu Gly Val Phe Asp Arg Met Lys Val Ala Leu Asp Lys Val Ile
                 85                  90                  95

Glu Ile Val Thr Asp Cys Lys Pro Asn Gly Glu Thr Asp Ile Ser Ser
            100                 105                 110

Ile Ser Ile Phe Thr Gly Ile Lys Glu Phe Lys Met Asn Ile Glu Ala
        115                 120                 125

Leu Arg Glu Asn Leu Tyr Phe Gln Ser Lys Glu Asn Leu Ser Val Thr
    130                 135                 140

Leu Glu Val Ile Leu Glu Arg Met Glu Asp Phe Thr Asp Ser Ala Tyr
145                 150                 155                 160

Thr Ser His Glu His Arg Glu Arg Ile Leu Glu Leu Ser Thr Gln Ala
                165                 170                 175

Arg Met Glu Leu Gln Gln Leu Ile Ser Val Trp Ile Gln Ala Gln Ser
            180                 185                 190

Lys Lys Thr Lys Ser Ile Ala Glu Glu Leu Glu Leu Ser Ile Leu Lys
        195                 200                 205

Ile Ser His Ser Leu Asn Glu Leu Lys Lys Glu Leu His Ser Thr Ala
    210                 215                 220

Thr Gln Leu Ala Ala Asp Leu Leu Lys Tyr His Ala Asp His Val Val
225                 230                 235                 240

Leu Lys Ala Leu Lys Leu Thr Gly Val Glu Gly Asn Leu Glu Ala Leu
                245                 250                 255

Ala Glu Tyr Ala Cys Lys Leu Ser Glu Gln Lys Glu Gln Leu Val Glu
            260                 265                 270

Thr Cys Arg Leu Leu Arg His Ile Ser Gly Thr Glu Pro Leu Glu Ile
        275                 280                 285

Thr Cys Ile His Ala Glu Glu Thr Phe Gln Val Thr Gly Gln Gln Ile
    290                 295                 300

Ile Ser Ala Ala Glu Thr Leu Thr Leu His Pro Ser Ser Lys Ile Ala
305                 310                 315                 320

Lys Glu Asn Leu Asp Val Phe Cys Glu Ala Trp Glu Ser Gln Ile Ser
                325                 330                 335

Asp Met Ser Thr Leu Leu Arg Glu Ile Asn Asp Val Phe Glu Gly Arg
            340                 345                 350

Arg Gly Glu Lys Tyr Gly Tyr Leu Ser Leu Pro Lys Pro Met Lys Asn
        355                 360                 365

Asn Ala Asn Leu Lys Ser Leu Lys Pro Asp Lys Pro Asp Ser Glu Glu
    370                 375                 380

Gln Ala Lys Ile Ala Lys Leu Gly Leu Lys Leu Gly Leu Leu Thr Ser
385                 390                 395                 400

Asp Ala Asp Cys Glu Ile Glu Lys Trp Glu Asp Gln Glu Asn Glu Ile
                405                 410                 415

Val Gln Tyr Gly Arg Asn Met Ser Ser Met Ala Tyr Ser Leu Tyr Leu
            420                 425                 430

Phe Thr Arg Gly Glu Gly Pro Leu Lys Thr Ser Gln Asp Leu Ile His
        435                 440                 445

Gln Leu Glu Val Phe Ala Ala Glu Gly Leu Lys Leu Thr Ser Ser Val
    450                 455                 460

Gln Ala Phe Ser Lys Gln Leu Xaa Asp Asp Asp Lys Leu Met Leu Leu
465                 470                 475                 480

Leu Glu Ile Asn Lys Leu Ile Pro Leu Cys His Gln Leu Gln Thr Val
                485                 490                 495

Thr Lys Thr Ser Leu Gln Asn Lys Val Phe Leu Lys Val Asp Lys Cys
            500                 505                 510

Ile Thr Lys Thr Arg Ser Met Met Ala Leu Leu Val Gln Leu Leu Ser
        515                 520                 525

Leu Cys Tyr Lys Leu Leu Lys Lys Leu Gln Met Glu Asn Asn Gly Trp
    530                 535                 540

Val Ser Val Thr Asn Lys Asp Thr Met Asp Ser Lys Thr 
545                 550                 555



<210> 1693
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1693
Met Thr Glu Gln Glu Lys Thr Ser Ala Val Val Glu Glu Thr Arg Glu
  1               5                  10                  15

Ala Val Asp Thr Thr Ser Gln Pro Val Ala Thr Glu Lys Lys Ser Lys
             20                  25                  30

Asn Asn Thr Ala Leu Ile Leu Ser Ala Val Ala Ile Ala Ile Ala Leu
         35                  40                  45

Ala Ala Gly Ile Gly Leu Tyr Gly Trp Gly Lys Gln Gln Ala Val Asn
     50                  55                  60

Gln Thr Ala Thr Ser Asp Ala Leu Ala Asn Gln Leu Thr Ala Leu Gln
 65                  70                  75                  80

Lys Ala Gln Glu Ser Gln Lys Ala Glu Leu Glu Gly Ile Ile Lys Gln
                 85                  90                  95

Gln Ala Ala Gln Leu Lys Gln Ala Asn Arg Gln Gln Glu Thr Leu Ala
            100                 105                 110

Lys Gln Leu Asp Glu Val Gln Gln Lys Val Ala Thr Ile Phe Arg Ser
        115                 120                 125

Asp Ala Xaa Thr Cys Cys Trp Leu Xaa Pro Xaa Phe Trp 
    130                 135                 140



<210> 1694
<211> 140
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1694
Met Arg Glu Glu Arg Trp Ser Cys Arg Gly Ser Gly Pro Pro Arg Ala
  1               5                  10                  15

Trp Ala Asp Glu Arg Xaa Arg Glu Pro Arg Pro Arg Val Leu Arg Val
             20                  25                  30

Arg Gly Asp Gly Ala Ser Glu Glu Met Glu Gln Lys Leu Val Glu Glu
         35                  40                  45

Ile Leu Gln Ala Ile Thr Met Ser Thr Asp Thr Gly Val Ser Leu Pro
     50                  55                  60

Ser Tyr Glu Glu Asp Gln Gly Ser Lys Leu Ile Arg Lys Ala Lys Glu
 65                  70                  75                  80

Ala Pro Phe Val Pro Val Gly Ile Ala Gly Phe Ala Ala Ile Val Ala
                 85                  90                  95

Tyr Gly Leu Tyr Lys Leu Lys Ser Arg Gly Asn Thr Lys Met Ser Ile
            100                 105                 110

His Leu Xaa His Met Arg Val Ala Ala Gln Gly Phe Val Val Gly Ala
        115                 120                 125

Xaa Leu Trp Tyr Gly Leu Phe Gln Tyr Ser Gly Phe 
    130                 135                 140



<210> 1695
<211> 140
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1695
Met Asn Gly Gly Glu Ala Gly Asp Val Glu Thr Val Ser Gln Gly Ser
  1               5                  10                  15

Asp Leu Asp Asp Ser Val Asp Asp Cys Met Gly Cys Arg Tyr Pro Ser
             20                  25                  30

Trp Ala Phe Leu Phe Leu Leu Gly Leu Tyr Ile Ser Ser Leu Ala Ser
         35                  40                  45

Cys Met Gly Gly Leu Tyr Gly Ala Pro Arg Ile Leu Gln Cys Ile Ala
     50                  55                  60

Gln Xaa Lys Val Ile Pro Ala Leu Ala Cys Leu Gly Gln Gly Lys Gly
 65                  70                  75                  80

Pro Asn Lys Thr Pro Val Ala Ala Ile Cys Leu Thr Ser Leu Val Thr
                 85                  90                  95

Met Ala Phe Val Phe Val Gly Gln Val Asn Val Leu Ala Pro Ile Val
            100                 105                 110

Thr Ile Asn Phe Met Leu Thr Tyr Val Ala Val Asp Tyr Ser Tyr Phe
        115                 120                 125

Ser Leu Ser Met Cys Ser Cys Ser Leu Thr Pro Val 
    130                 135                 140



<210> 1696
<211> 311
<212> PRT
<213> Homo sapiens

<400> 1696
Met Glu Leu Gln Gly His Ile Gly Arg Phe Gln Arg Gln Cys Leu Gly
  1               5                  10                  15

Leu Leu Ser Arg Phe Gly Gly Ser Asp Arg Leu Arg Gln Phe Lys Phe
             20                  25                  30

Gln Asp Asp Asn Val Glu Gly Asp Lys Val Ser Lys Lys Asp Glu Ile
         35                  40                  45

Glu Leu Ala Met Gln Gln Ile Cys Ala Asn Val Met Glu Tyr Cys Gln
     50                  55                  60

Ser Leu Met Leu Gln Ser Ser Pro Thr Phe Gln His Ala Val Cys Leu
 65                  70                  75                  80

Phe Thr Pro Ser Leu Ser Glu Thr Val Asn Arg Asp Gly Pro Arg Gln
                 85                  90                  95

Asp Thr Gln Ala Pro Val Val Pro Tyr Trp Arg Leu Pro Gly Leu Gly
            100                 105                 110

Ile Ile Ile Tyr Leu Leu Lys Gln Ser Ala Asn Asp Phe Phe Ser Tyr
        115                 120                 125

Tyr Asp Ser His Arg Gln Ser Val Ser Lys Leu Gln Asn Val Glu Gln
    130                 135                 140

Leu Pro Pro Asp Glu Ile Lys Glu Leu Cys Gln Ser Val Met Pro Ala
145                 150                 155                 160

Gly Val Asp Lys Ile Ser Thr Ala Gln Lys Tyr Val Leu Ala Arg Arg
                165                 170                 175

Arg Leu Val Lys Val Ile Asn Asn Arg Ala Lys Leu Leu Ser Leu Cys
            180                 185                 190

Ser Phe Ile Ile Glu Thr Cys Leu Phe Ile Leu Trp Arg His Leu Glu
        195                 200                 205

Tyr Tyr Leu Leu His Cys Met Pro Thr Asp Ser Gln Asp Ser Leu Phe
    210                 215                 220

Ala Ser Arg Thr Leu Phe Lys Ser Arg Arg Leu Gln Asp Ser Phe Ala
225                 230                 235                 240

Ser Glu Thr Asn Leu Asp Phe Arg Ser Gly Leu Ala Ile Val Ser Gln
                245                 250                 255

His Asp Leu Asp Gln Leu Gln Ala Asp Ala Ile Asn Ala Phe Gly Glu
            260                 265                 270

Ser Leu Gln Lys Lys Leu Leu Asp Ile Glu Gly Leu Tyr Ser Lys Val
        275                 280                 285

Arg Ser Arg Tyr Ser Phe Ile Gln Ala Leu Val Arg Arg Ile Arg Gly
    290                 295                 300

Leu Leu Arg Ile Ser Arg Asn 
305                 310



<210> 1697
<211> 224
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (59)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1697
Met Asp Met Tyr Ala Trp Thr Gln Glu Gln Ala Val Leu Tyr Asn Gly
  1               5                  10                  15

Ile Ile Leu Ala Ala Leu Gly Val Glu Ala Val Val Ile Phe Leu Gly
             20                  25                  30

Val Lys Leu Leu Ser Lys Lys Ile Gly Glu Arg Ala Ile Leu Leu Gly
         35                  40                  45

Gly Leu Ile Val Val Trp Val Gly Phe Phe Xaa Leu Leu Pro Trp Gly
     50                  55                  60

Asn Gln Phe Pro Lys Ile Gln Trp Glu Asp Leu His Asn Asn Ser Ile
 65                  70                  75                  80

Pro Asn Thr Thr Phe Gly Glu Ile Ile Ile Gly Leu Trp Lys Ser Pro
                 85                  90                  95

Met Glu Asp Asp Asn Glu Arg Pro Thr Gly Cys Ser Ile Glu Gln Ala
            100                 105                 110

Trp Cys Leu Tyr Thr Pro Val Ile His Leu Ala Gln Phe Leu Thr Ser
        115                 120                 125

Ala Val Leu Ile Gly Leu Gly Tyr Pro Val Cys Asn Leu Met Ser Tyr
    130                 135                 140

Thr Leu Tyr Ser Lys Ile Leu Gly Pro Lys Pro Gln Gly Val Tyr Met
145                 150                 155                 160

Gly Trp Leu Thr Ala Ser Gly Ser Gly Ala Arg Ile Leu Gly Pro Met
                165                 170                 175

Phe Ile Ser Gln Val Tyr Ala His Trp Gly Pro Arg Trp Ala Phe Ser
            180                 185                 190

Leu Val Cys Gly Ile Ile Val Leu Thr Ile Thr Leu Leu Gly Val Val
        195                 200                 205

Tyr Lys Arg Leu Ile Ala Leu Ser Val Arg Tyr Gly Arg Ile Gln Glu
    210                 215                 220






<210> 1698
<211> 104
<212> PRT
<213> Homo sapiens

<400> 1698
Met Val Lys Ile Ala Phe Asn Thr Pro Thr Ala Val Gln Lys Glu Glu
  1               5                  10                  15

Ala Arg Gln Asp Val Glu Ala Leu Leu Ser Arg Thr Val Arg Thr Gln
             20                  25                  30

Ile Leu Thr Gly Lys Ser Thr Ile Tyr Arg Gly Glu Met Cys Phe Phe
         35                  40                  45

Asp Ser Glu Asp Pro Ala Asn Ser Leu Arg Gly Gly Glu Pro Asn Phe
     50                  55                  60

Leu Pro Val Thr Glu Glu Ala Asp Ile Arg Glu Asp Asp Asn Ile Ala
 65                  70                  75                  80

Ile Ile Asp Val Pro Val Pro Ile Ser Leu Ile Val Thr Leu Gln Gln
                 85                  90                  95

Leu Phe Met Thr Leu Lys Arg Glu 
            100



<210> 1699
<211> 108
<212> PRT
<213> Homo sapiens

<400> 1699
Met Ala Glu Met Val Asp Phe Phe Ile Leu Phe Phe Ile Lys Ala Thr
  1               5                  10                  15

Ile Val Leu Ser Ile Met His Leu Ser Gly Ile Lys Asp Ile Ser Lys
             20                  25                  30

Phe Ala Met His Tyr Ile Ile Glu Glu Ile Asp Glu Asp Thr Ser Met
         35                  40                  45

Glu Asp Leu Gln Lys Met Met Val Val Ala Leu Ile Tyr Arg Leu Leu
     50                  55                  60

Val Cys Phe Tyr Glu Ile Ile Cys Ile Trp Gly Ala Gly Gly Ala Thr
 65                  70                  75                  80

Pro Gly Lys Phe Leu Leu Gly Leu Arg Val Val Thr Cys Asp Thr Ser
                 85                  90                  95

Val Leu Ile Ala Pro Ser Arg Val Phe Ser Asp Ser 
            100                 105



<210> 1700
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1700
Met Glu Leu Pro Val Leu Leu Leu His Gln Leu Ser Lys Phe Asp Pro
  1               5                  10                  15

Ser Tyr Gln Met Thr Thr Asp Glu Gln Gln Ile Ile Asn Ser Phe Tyr
             20                  25                  30

Thr Val Phe Arg Glu Glu Tyr Thr Ala Ile Glu Asp Leu Phe Ser Ala
         35                  40                  45

Ile Asn Lys Thr Glu Ala Val Arg Cys Glu Tyr Glu Asp Thr His Lys
     50                  55                  60

Ala Phe Ala Lys Ala Phe Trp Arg Met Asp Arg Leu Leu Gly Leu Gly
 65                  70                  75                  80

Arg Lys Glu Val Ser Arg Val Gln Trp Ser Gly Cys Ser Ala Val Thr
                 85                  90                  95

Xaa Ile Leu Glu Gly Lys Pro Lys Ser Pro Tyr Ala His Lys Asn Trp
            100                 105                 110

Lys Arg Lys Asn Thr His Asp Gly Leu Ala Glu Ser Ser Pro Xaa Gln
        115                 120                 125

Glu Met Pro Lys Ile Ile Ser Gly Ile Leu His Val Ala Asn Thr Asp
    130                 135                 140

Val Ile Leu Gly Val Ile Cys His Ile Cys Lys Met Ser Ile Leu Ser
145                 150                 155                 160

His Asn Pro Ser Gln Leu Cys Gln His Phe Pro Ser Lys Leu Gln Thr
                165                 170                 175






<210> 1701
<211> 147
<212> PRT
<213> Homo sapiens

<400> 1701
Met Asn Ser Leu Leu His Phe Gly Ile Leu Leu Glu Leu Gly Val Ser
  1               5                  10                  15

Trp Lys Gln Phe Lys Ser Val Tyr Val Pro Gly Asn His Thr His Gln
             20                  25                  30

Ala Ser Tyr Lys Pro Leu Leu Lys Gln Val Val Glu Glu Ile Phe His
         35                  40                  45

Pro Glu Arg Pro Asp Ser Val Asp Ile Glu His Met Ser Ser Gly Leu
     50                  55                  60

Thr Asp Leu Leu Lys Thr Gly Phe Ser Met Phe Met Lys Val Ser Arg
 65                  70                  75                  80

Pro His Pro Ser Asp Tyr Pro Leu Leu Ile Leu Phe Val Val Gly Gly
                 85                  90                  95

Val Thr Val Ser Glu Val Lys Met Val Lys Asp Leu Val Ala Ser Leu
            100                 105                 110

Lys Pro Gly Thr Gln Val Ile Val Leu Ser Thr Arg Leu Leu Lys Pro
        115                 120                 125

Leu Asn Ile Pro Glu Leu Leu Phe Ala Thr Asp Arg Leu His Pro Asp
    130                 135                 140

Leu Gly Phe 
145



<210> 1702
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1702
Met Gly Ser Ile Thr Cys Ile Ala Trp Lys Gly Asp Thr Leu Val Leu
  1               5                  10                  15

Gly Asp Met Asp Gly Asn Leu Asn Phe Trp Asp Leu Lys Gly Arg Val
             20                  25                  30

Ser Arg Tyr Lys Pro Arg Met Asn Leu Val Ile Ser Leu Lys Lys Xaa
         35                  40                  45

Asn Glu Ile Phe Leu Phe Cys Phe Val Leu Phe Cys Phe Val Glu Met
     50                  55                  60

Val Ser Cys Ser Val Ala Gln Ala Gly Val Gln Trp Cys Asn Leu Gly
 65                  70                  75                  80

Ser Leu Gln Ala Leu Thr Pro Gly Phe Met Pro Phe Ser Cys Phe Ser
                 85                  90                  95

Tyr Leu Gly Asn 
            100



<210> 1703
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1703
Met Asn Gln Thr Asp Lys Asn Gln Gln Glu Ile Pro Ser Tyr Leu Asn
  1               5                  10                  15

Asp Glu Pro Pro Glu Gly Ser Met Lys Asp His Pro Gln Gln Gln Pro
             20                  25                  30

Gly Met Leu Ser Arg Val Thr Gly Gly Ile Phe Ser Val Thr Lys Gly
         35                  40                  45

Ala Val Gly Ala Thr Ile Gly Xaa Val Ala Trp Ile Gly Gly Lys Ser
     50                  55                  60

Leu Glu Val Thr Lys Thr Ala Val Thr Thr Val Pro Ser Met Gly Ile
 65                  70                  75                  80

Gly Leu Val Lys Gly Gly Val Ser Ala Val Ala Gly Gly Val Thr Ala
                 85                  90                  95

Val Gly Ser Ala Val Val Asn Lys Val Pro Leu Thr Gly Lys Lys Lys
            100                 105                 110

Asp Lys Ser Asp 
        115



<210> 1704
<211> 308
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (241)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (291)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1704
Met Ala Lys Arg Glu Ile Leu Ser Ala Ala Glu His Phe Ser Met Ile
  1               5                  10                  15

Arg Ala Ser Arg Asn Lys Asn Gly Pro Ala Leu Gly Gly Leu Ser Cys
             20                  25                  30

Ser Pro Asn Leu Pro Gly Gln Thr Thr Val Gln Val Arg Val Pro Tyr
         35                  40                  45

Arg Val Val Gly Leu Val Val Gly Pro Lys Gly Ala Thr Ile Lys Arg
     50                  55                  60

Ile Gln Gln Gln Thr His Thr Tyr Ile Val Thr Pro Ser Arg Asp Lys
 65                  70                  75                  80

Xaa Pro Val Phe Glu Val Thr Gly Met Pro Glu Asn Val Asp Arg Ala
                 85                  90                  95

Arg Glu Glu Ile Glu Met His Ile Ala Met Arg Thr Gly Asn Tyr Ile
            100                 105                 110

Glu Leu Asn Glu Glu Asn Asp Phe His Tyr Asn Gly Thr Asp Val Ser
        115                 120                 125

Phe Glu Gly Gly Thr Leu Gly Ser Ala Trp Leu Ser Ser Asn Pro Val
    130                 135                 140

Pro Pro Ser Arg Ala Arg Met Ile Ser Asn Tyr Arg Asn Asp Ser Ser
145                 150                 155                 160

Ser Ser Leu Gly Ser Gly Ser Thr Asp Ser Tyr Phe Gly Ser Asn Arg
                165                 170                 175

Leu Xaa Asp Phe Ser Pro Thr Ser Pro Phe Ser Thr Gly Asn Phe Trp
            180                 185                 190

Phe Gly Xaa Thr Leu Pro Ser Val Gly Ser Glu Asp Leu Ala Val Asp
        195                 200                 205

Ser Pro Ala Phe Asp Ser Leu Pro Thr Ser Ala Gln Thr Ile Trp Thr
    210                 215                 220

Pro Phe Glu Pro Val Asn Pro Leu Ser Gly Phe Gly Ser Asp Pro Ser
225                 230                 235                 240

Xaa Asn Met Lys Thr Gln Arg Arg Gly Ser Gln Pro Ser Thr Pro Arg
                245                 250                 255

Leu Ser Pro Thr Phe Pro Glu Ser Ile Glu His Pro Leu Ala Arg Arg
            260                 265                 270

Val Arg Ser Asp Pro Pro Ser Thr Gly Asn His Val Gly Leu Pro Ile
        275                 280                 285

Tyr Ile Xaa Ala Phe Leu Met Val Pro Ile Val Thr Pro Leu Pro Met
    290                 295                 300

Val Val Pro Leu 
305



<210> 1705
<211> 132
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1705
Met Ser Glu Val Arg Leu Pro Pro Leu Arg Ala Leu Asp Asp Phe Val
  1               5                  10                  15

Leu Gly Ser Ala Arg Leu Ala Ala Pro Asp Pro Cys Asp Pro Gln Arg
             20                  25                  30

Trp Cys His Arg Val Ile Asn Asn Leu Leu Tyr Tyr Gln Thr Asn Tyr
         35                  40                  45

Leu Leu Cys Phe Gly Ile Gly Leu Ala Leu Ala Gly Tyr Val Arg Pro
     50                  55                  60

Leu His Thr Leu Leu Ser Ala Leu Val Val Ala Val Ala Leu Gly Val
 65                  70                  75                  80

Leu Val Trp Ala Ala Glu Thr Arg Ala Leu Cys Ala Ala Ala Ala Ala
                 85                  90                  95

Ala Thr Leu Gln Pro Ala Trp Pro Xaa Cys Leu Pro Ser Ala Ser Trp
            100                 105                 110

Cys Ser Gly Ser Arg Ala Xaa Leu Ala Xaa Ser Cys Ser Ala Ser Pro
        115                 120                 125

Gly Arg Cys Phe 
    130



<210> 1706
<211> 177
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1706
Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile
  1               5                  10                  15

Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu
             20                  25                  30

Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro
         35                  40                  45

Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala
     50                  55                  60

Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg
 65                  70                  75                  80

Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser
                 85                  90                  95

Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Val Ala
            100                 105                 110

Ala Ile Val Leu Phe Cys Ser Thr Ser Ser Pro His Ser Ile Pro Leu
        115                 120                 125

Thr Glu Val Ile Gly Pro Asp Met Ala Gly Cys Xaa Xaa Trp Gly Thr
    130                 135                 140

Gly Ala Leu Ala Arg Ile Gly Phe His Lys Xaa His Pro Lys Thr Leu
145                 150                 155                 160

Leu Leu Ser Thr Arg Gly Gly Leu Lys Lys Glu Arg Lys Gly Lys Ile
                165                 170                 175

Lys 




<210> 1707
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (31)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1707
Met Phe Pro Leu Ile Ser Ser His His Leu Trp Xaa Xaa Trp Ala Ser
  1               5                  10                  15

Glu Asp Ser Leu Ser Glu Pro Ala Ser Ala Asp Pro Ala Ala Xaa Gln
             20                  25                  30

His Met His Ile Lys Val Gly Asp Arg Ala Glu Leu Arg Arg Ala Phe
         35                  40                  45

Thr Gln Thr Asp Val Ala Thr Phe Ser Glu Leu Thr Gly Asp Val Asn
     50                  55                  60

Pro Leu His Leu Asn Glu Asp Phe Ala Lys His Thr Lys Phe Gly Asn
 65                  70                  75                  80

Thr Ile Val His Gly Val Leu Ile Asn Gly Leu Ile Ser Ala Leu Leu
                 85                  90                  95

Gly Thr Lys Met Pro Gly Pro Gly Cys Val Phe Leu Ser Gln Glu Ile
            100                 105                 110

Ser Phe Pro Ala Pro Leu Tyr Ile Gly Glu Val Val Leu Ala Ser Ala
        115                 120                 125

Glu Val Lys Lys Leu Lys Arg Phe Ile Ala Ile Ile Ala Val Ser Cys
    130                 135                 140

Ser Val Ile Glu Ser Lys Lys Thr Val Met Glu Gly Trp Val Lys Val
145                 150                 155                 160

Met Val Pro Glu Ala Ser Lys Ser 
                165



<210> 1708
<211> 372
<212> PRT
<213> Homo sapiens

<400> 1708
Met Arg Tyr Ala Val Tyr Trp Asp Glu Leu Ala Ser Glu Val Arg Arg
  1               5                  10                  15

Cys Thr Trp Phe Tyr Lys Gly Asp Lys Asp Asn Lys Tyr Val Pro Tyr
             20                  25                  30

Ser Glu Ser Phe Ser Gln Val Leu Glu Glu Thr Tyr Met Leu Ala Val
         35                  40                  45

Thr Leu Asp Glu Trp Lys Lys Lys Leu Glu Ser Pro Asn Arg Glu Ile
     50                  55                  60

Ile Ile Leu His Asn Pro Lys Leu Met Val His Tyr Gln Pro Val Ala
 65                  70                  75                  80

Gly Ser Asp Asp Trp Gly Ser Thr Pro Thr Glu Gln Gly Arg Pro Arg
                 85                  90                  95

Thr Val Lys Arg Gly Val Glu Asn Ile Ser Val Asp Ile His Cys Gly
            100                 105                 110

Glu Pro Leu Gln Ile Asp His Leu Val Phe Val Val His Gly Ile Gly
        115                 120                 125

Pro Ala Cys Asp Leu Arg Phe Arg Ser Ile Val Gln Cys Val Asn Asp
    130                 135                 140

Phe Arg Ser Val Ser Leu Asn Leu Leu Gln Thr His Phe Lys Lys Ala
145                 150                 155                 160

Gln Glu Asn Gln Gln Ile Gly Arg Val Glu Phe Leu Pro Val Asn Trp
                165                 170                 175

His Ser Pro Leu His Ser Thr Gly Val Asp Val Asp Leu Gln Arg Ile
            180                 185                 190

Thr Leu Pro Ser Ile Asn Arg Leu Arg His Phe Thr Asn Asp Thr Ile
        195                 200                 205

Leu Asp Val Phe Phe Tyr Asn Ser Pro Thr Tyr Cys Gln Thr Ile Val
    210                 215                 220

Asp Thr Val Ala Ser Glu Met Asn Arg Ile Tyr Thr Leu Phe Leu Gln
225                 230                 235                 240

Arg Asn Pro Asp Phe Lys Gly Gly Val Ser Ile Ala Gly His Ser Leu
                245                 250                 255

Gly Ser Leu Ile Leu Phe Asp Ile Leu Thr Asn Gln Lys Asp Ser Leu
            260                 265                 270

Gly Asp Ile Asp Ser Glu Lys Asp Ser Leu Asn Ile Val Met Asp Gln
        275                 280                 285

Gly Asp Thr Pro Thr Leu Glu Glu Asp Leu Lys Lys Leu Gln Leu Ser
    290                 295                 300

Glu Phe Phe Asp Ile Phe Glu Lys Glu Lys Val Asp Lys Glu Ala Leu
305                 310                 315                 320

Ala Leu Cys Thr Asp Arg Asp Leu Gln Glu Ile Gly Ile Pro Leu Gly
                325                 330                 335

Pro Arg Lys Lys Ile Leu Asn Tyr Phe Gln His Pro Glu Lys Thr Pro
            340                 345                 350

Met Gly Ile Lys Arg Pro Ala Arg Ser Leu Leu Pro Gly Ala Thr Ile
        355                 360                 365

Pro Lys Glu Ser 
    370



<210> 1709
<211> 362
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1709
Met Asp Leu Leu Lys Gln Glu Ala Glu His Gly Ala Leu Lys Val Leu
  1               5                  10                  15

Tyr Leu Ser Lys Tyr Val Leu Asn Met Met Ala Leu Leu Cys Ala Pro
             20                  25                  30

Val Arg Asp Glu Ala Val Gln Lys Leu Glu Asn Ile Thr Asp Pro Val
         35                  40                  45

Trp Leu Leu Arg Gly Xaa Phe Gln Val Leu Gly Arg Met Lys Met Asp
     50                  55                  60

Met Val Asn Tyr Thr Ile Gln Ser Leu Gln Pro His Leu Gln Glu His
 65                  70                  75                  80

Ser Ile Gln Tyr Glu Arg Ala Lys Phe Gln Glu Leu Leu Asn Lys Gln
                 85                  90                  95

Pro Ser Leu Leu Asn His Thr Thr Lys Trp Leu Thr Gln Ala Ala Gly
            100                 105                 110

Asp Leu Thr Met Ser Pro Pro Thr Cys Pro Asp Thr Ser Asp Ser Ser
        115                 120                 125

Ser Val Ala Gly Pro Ser Pro Asn Glu Ala Ala Asn Asn Pro Glu Pro
    130                 135                 140

Leu Ser Pro Thr Met Val Leu Cys Gln Gly Phe Leu Asn Leu Leu Leu
145                 150                 155                 160

Trp Asp Leu Glu Asn Glu Glu Phe Pro Glu Thr Leu Leu Met Asp Arg
                165                 170                 175

Thr Arg Leu Gln Glu Leu Lys Ser Gln Leu His Gln Leu Thr Val Met
            180                 185                 190

Xaa Ser Val Leu Leu Val Ala Ser Ser Phe Ser Gly Ser Val Leu Phe
        195                 200                 205

Gly Ser Pro Gln Phe Val Asp Lys Leu Lys Arg Ile Thr Lys Ser Leu
    210                 215                 220

Leu Glu Asp Phe His Ser Arg Pro Glu Glu Ala Ile Leu Thr Val Ser
225                 230                 235                 240

Glu Gln Val Ser Gln Glu Ile His Gln Ser Leu Lys Asn Met Gly Leu
                245                 250                 255

Val Ala Leu Ser Ser Asp Asn Thr Ala Ser Leu Met Gly Gln Leu Gln
            260                 265                 270

Asn Ile Ala Lys Lys Glu Asn Cys Val Cys Ser Val Ile Asp Gln Arg
        275                 280                 285

Ile His Leu Phe Leu Lys Cys Cys Leu Val Leu Gly Val Gln Arg Ser
    290                 295                 300

Leu Leu Asp Leu Pro Gly Gly Leu Thr Leu Ile Glu Ala Glu Leu Ala
305                 310                 315                 320

Glu Leu Gly Gln Lys Phe Val Asn Leu Thr His His Asn Gln Gln Val
                325                 330                 335

Phe Gly Pro Tyr Tyr Thr Glu Ile Leu Lys Thr Leu Ile Ser Pro Ala
            340                 345                 350

Gln Ala Leu Glu Thr Lys Val Glu Ser Val 
        355                 360



<210> 1710
<211> 338
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (309)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1710
Met Glu Leu Trp Gly Arg Met Leu Trp Ala Leu Leu Ser Gly Pro Gly
  1               5                  10                  15

Arg Arg Gly Ser Thr Arg Gly Trp Ala Phe Ser Ser Trp Gln Pro Gln
             20                  25                  30

Pro Pro Leu Ala Gly Leu Ser Ser Ala Ile Glu Leu Val Ser His Trp
         35                  40                  45

Thr Gly Val Phe Glu Lys Arg Gly Ile Pro Glu Ala Arg Glu Ser Ser
     50                  55                  60

Glu Tyr Ile Val Ala His Val Leu Gly Ala Lys Thr Phe Gln Ser Leu
 65                  70                  75                  80

Arg Pro Ala Leu Trp Thr Gln Pro Leu Thr Ser Gln Gln Leu Gln Cys
                 85                  90                  95

Ile Arg Glu Leu Ser Ser Arg Arg Leu Gln Arg Met Pro Val Gln Tyr
            100                 105                 110

Ile Leu Gly Glu Trp Asp Phe Gln Gly Leu Ser Leu Arg Met Val Pro
        115                 120                 125

Pro Val Phe Ile Pro Arg Pro Glu Thr Glu Glu Leu Val Glu Trp Val
    130                 135                 140

Leu Glu Glu Val Ala Gln Arg Ser His Ala Val Gly Ser Pro Gly Ser
145                 150                 155                 160

Pro Leu Ile Leu Glu Val Gly Cys Gly Ser Gly Ala Ile Ser Leu Ser
                165                 170                 175

Leu Leu Ser Gln Leu Pro Gln Ser Arg Val Ile Ala Val Asp Lys Arg
            180                 185                 190

Glu Ala Ala Ile Ser Leu Thr His Glu Asn Ala Gln Arg Leu Arg Leu
        195                 200                 205

Gln Asp Arg Ile Trp Ile Ile His Leu Asp Met Thr Ser Glu Arg Ser
    210                 215                 220

Trp Thr His Leu Pro Trp Gly Pro Met Asp Leu Ile Val Ser Asn Pro
225                 230                 235                 240

Pro Tyr Val Phe His Gln Asp Met Glu Gln Leu Ala Pro Glu Ile Arg
                245                 250                 255

Ser Tyr Glu Asp Pro Ala Ala Leu Asp Gly Gly Glu Glu Gly Met Asp
            260                 265                 270

Ile Ile Thr His Ile Leu Ala Leu Ala Pro Arg Leu Leu Lys Asp Ser
        275                 280                 285

Gly Ser Ile Phe Leu Glu Val Asp Pro Arg His Pro Glu Leu Val Ser
    290                 295                 300

Ser Trp Leu Gln Xaa Arg Pro Asp Leu Tyr Leu Asn Leu Val Ala Val
305                 310                 315                 320

Arg Arg Asp Phe Cys Gly Arg Pro Arg Phe Leu His Ile Arg Arg Ser
                325                 330                 335

Gly Pro 




<210> 1711
<211> 110
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1711
Met Met Cys Ala Val Leu Ser Arg Asn Thr Phe Ile Ile Ile Ile Lys
  1               5                  10                  15

Tyr Cys Val Leu Tyr Arg Met Met Cys Ala Val Leu Ser Arg Asn Thr
             20                  25                  30

Phe Ile Ile Ile Ile Lys Tyr Cys Val Leu Tyr Arg Met Val Cys Ala
         35                  40                  45

Val Leu Ser Arg Asn Thr Phe Ile Ile Ile Ile Xaa Tyr Cys Val Leu
     50                  55                  60

Tyr Arg Met Val Cys Ala Val Leu Ser Arg Asn Thr Phe Ile Ile Ile
 65                  70                  75                  80

Ile Lys Tyr Cys Val Leu Tyr Arg Met Val Cys Ala Val Leu Leu Cys
                 85                  90                  95

Lys Trp Gln His Ser Ser Phe Thr Arg Ala Ser Leu Asp Thr 
            100                 105                 110



<210> 1712
<211> 563
<212> PRT
<213> Homo sapiens

<400> 1712
Met Lys Ser Val Lys Ile Ala Phe Ala Val Thr Leu Glu Thr Val Leu
  1               5                  10                  15

Ala Gly His Glu Asn Trp Val Asn Ala Val His Trp Gln Pro Val Phe
             20                  25                  30

Tyr Lys Asp Gly Val Leu Gln Gln Pro Val Arg Leu Leu Ser Ala Ser
         35                  40                  45

Met Asp Lys Thr Met Ile Leu Trp Ala Pro Asp Glu Glu Ser Gly Val
     50                  55                  60

Trp Leu Glu Gln Val Arg Val Gly Glu Val Gly Gly Asn Thr Leu Gly
 65                  70                  75                  80

Phe Tyr Asp Cys Gln Phe Asn Glu Asp Gly Ser Met Ile Ile Ala His
                 85                  90                  95

Ala Phe His Gly Ala Leu His Leu Trp Lys Gln Asn Thr Val Asn Pro
            100                 105                 110

Arg Glu Trp Thr Pro Glu Ile Val Ile Ser Gly His Phe Asp Gly Val
        115                 120                 125

Gln Asp Leu Val Trp Asp Pro Glu Gly Glu Phe Ile Ile Thr Val Gly
    130                 135                 140

Thr Asp Gln Thr Thr Arg Leu Phe Ala Pro Trp Lys Arg Lys Asp Gln
145                 150                 155                 160

Ser Gln Val Thr Trp His Glu Ile Ala Arg Pro Gln Ile His Gly Tyr
                165                 170                 175

Asp Leu Lys Cys Leu Ala Met Ile Asn Arg Phe Gln Phe Val Ser Gly
            180                 185                 190

Ala Asp Glu Lys Val Leu Arg Val Phe Ser Ala Pro Arg Asn Phe Val
        195                 200                 205

Glu Asn Phe Cys Ala Ile Thr Gly Gln Ser Leu Asn His Val Leu Cys
    210                 215                 220

Asn Gln Asp Ser Asp Leu Pro Glu Gly Ala Thr Val Pro Ala Leu Gly
225                 230                 235                 240

Leu Ser Asn Lys Ala Val Phe Gln Gly Asp Ile Ala Ser Gln Pro Ser
                245                 250                 255

Asp Glu Glu Glu Leu Leu Thr Ser Thr Gly Phe Glu Tyr Gln Gln Val
            260                 265                 270

Ala Phe Gln Pro Ser Ile Leu Thr Glu Pro Pro Thr Glu Asp His Leu
        275                 280                 285

Leu Gln Asn Thr Leu Trp Pro Glu Val Gln Lys Leu Tyr Gly His Gly
    290                 295                 300

Tyr Glu Ile Phe Cys Val Thr Cys Asn Ser Ser Lys Thr Leu Leu Ala
305                 310                 315                 320

Ser Ala Cys Lys Ala Ala Lys Lys Glu His Ala Ala Ile Ile Leu Trp
                325                 330                 335

Asn Thr Thr Ser Trp Lys Gln Val Gln Asn Leu Val Phe His Ser Leu
            340                 345                 350

Thr Val Thr Gln Met Ala Phe Ser Pro Asn Glu Lys Phe Leu Leu Ala
        355                 360                 365

Val Ser Arg Asp Arg Thr Trp Ser Leu Trp Lys Lys Gln Asp Thr Ile
    370                 375                 380

Ser Pro Glu Phe Glu Pro Val Phe Ser Leu Phe Ala Phe Thr Asn Lys
385                 390                 395                 400

Ile Thr Ser Val His Ser Arg Ile Ile Trp Ser Cys Asp Trp Ser Pro
                405                 410                 415

Asp Ser Lys Tyr Phe Phe Thr Gly Ser Arg Asp Lys Lys Val Val Val
            420                 425                 430

Trp Gly Glu Cys Asp Ser Thr Asp Asp Cys Ile Glu His Asn Ile Gly
        435                 440                 445

Pro Cys Ser Ser Val Leu Asp Val Gly Gly Ala Val Thr Ala Val Ser
    450                 455                 460

Val Cys Pro Val Leu His Pro Ser Gln Arg Tyr Val Val Ala Val Gly
465                 470                 475                 480

Leu Glu Cys Gly Lys Ile Cys Leu Tyr Thr Trp Lys Lys Thr Asp Gln
                485                 490                 495

Val Pro Glu Ile Asn Asp Trp Thr His Cys Val Glu Thr Ser Gln Ser
            500                 505                 510

Gln Ser His Thr Leu Ala Ile Arg Lys Leu Cys Trp Lys Asn Cys Ser
        515                 520                 525

Gly Lys Thr Glu Gln Lys Glu Ala Glu Gly Ala Glu Trp Leu His Phe
    530                 535                 540

Ala Ser Cys Gly Glu Asp His Thr Val Lys Ile His Arg Val Asn Lys
545                 550                 555                 560

Cys Ala Leu 




<210> 1713
<211> 373
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1713
Met Ala Ser Glu Leu Cys Lys Thr Ile Ser Val Ala Arg Leu Glu Lys
  1               5                  10                  15

His Lys Asn Leu Phe Leu Asn Tyr Arg Asn Leu His His Phe Pro Leu
             20                  25                  30

Glu Leu Leu Lys Asp Glu Gly Leu Gln Tyr Leu Glu Arg Leu Tyr Met
         35                  40                  45

Lys Arg Asn Ser Leu Thr Ser Leu Pro Glu Asn Leu Ala Xaa Glu Ala
     50                  55                  60

Ser Lys Pro Cys Gly Thr Val Xaa Leu Xaa Leu Arg Tyr Leu His Ser
 65                  70                  75                  80

Asn Asn Ile Val Val Val Pro Glu Ala Ile Gly Ser Leu Val Lys Leu
                 85                  90                  95

Gln Cys Leu Asp Leu Ser Asp Asn Ala Leu Glu Ile Val Cys Pro Glu
            100                 105                 110

Ile Gly Arg Leu Arg Ala Leu Arg His Leu Arg Leu Ala Asn Asn Gln
        115                 120                 125

Leu Gln Phe Leu Pro Pro Glu Val Gly Asp Leu Lys Glu Leu Gln Thr
    130                 135                 140

Leu Asp Ile Ser Thr Asn Arg Leu Leu Thr Leu Pro Glu Arg Leu His
145                 150                 155                 160

Met Cys Leu Ser Leu Gln Tyr Leu Thr Val Asp Arg Asn Arg Leu Trp
                165                 170                 175

Tyr Val Pro Arg His Leu Cys Gln Leu Pro Ser Leu Asn Glu Leu Ser
            180                 185                 190

Met Ala Gly Asn Arg Leu Ala Phe Leu Pro Leu Asp Leu Gly Arg Ser
        195                 200                 205

Arg Glu Leu Gln Tyr Val Tyr Val Asp Asn Asn Ile His Leu Lys Gly
    210                 215                 220

Leu Pro Ser Tyr Leu Tyr Asn Lys Val Ile Gly Cys Ser Gly Cys Gly
225                 230                 235                 240

Ala Pro Ile Gln Val Ser Glu Val Lys Leu Leu Ser Phe Ser Ser Gly
                245                 250                 255

Gln Arg Thr Val Phe Leu Pro Ala Glu Val Lys Ala Ile Gly Thr Glu
            260                 265                 270

His Asp His Val Leu Pro Leu Gln Glu Leu Ala Met Arg Gly Leu Tyr
        275                 280                 285

His Thr Tyr His Ser Leu Leu Lys Asp Leu Asn Phe Leu Ser Pro Ile
    290                 295                 300

Ser Leu Pro Arg Ser Leu Leu Glu Leu Leu His Cys Pro Leu Gly His
305                 310                 315                 320

Cys His Arg Cys Ser Glu Pro Met Phe Thr Ile Val Tyr Pro Lys Leu
                325                 330                 335

Phe Pro Leu Arg Glu Thr Pro Met Ala Gly Leu His Gln Trp Lys Thr
            340                 345                 350

Thr Val Ser Phe Val Ala Tyr Cys Cys Ser Thr Gln Cys Leu Gln Thr
        355                 360                 365

Phe Asp Leu Leu Ser 
    370



<210> 1714
<211> 152
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1714
Met Xaa Gly Gln Thr Gly His Gly Gly Ser Thr Glu Pro Ala Pro His
  1               5                  10                  15

Val His Pro Gly Thr Xaa Gly Pro Xaa Leu His Gly Lys Thr Pro Leu
             20                  25                  30

Ser Ser Pro Leu Gly Ser Ala Thr Thr Arg Arg Ile Ser Arg Lys His
         35                  40                  45

Gln Arg Pro Gly Ser Ser Asp Pro Tyr Ser Gly Gly Leu Ser Pro Trp
     50                  55                  60

Glu Gly Thr Pro Glu Ala Ala Ser Ala Pro Ser Pro Val Pro Arg Thr
 65                  70                  75                  80

Ala Cys Arg Cys Leu Val Ala Gly Leu Xaa Ser Glu Arg Asp Cys Ser
                 85                  90                  95

Gly Trp Leu Asp Leu Gln Gly Thr Leu His Pro Ser Cys Gln Ala Leu
            100                 105                 110

Gly Gln Gln His Pro Leu Val Ala Ile Leu Cys Leu Xaa Pro Gly Gly
        115                 120                 125

Leu Pro Ile Gly Leu Leu Gly Gly Ala Gly Arg Ala Ser Ile Ala Gln
    130                 135                 140

Asn Cys Pro Lys Ala Leu Xaa Arg 
145                 150



<210> 1715
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (164)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1715
Met Phe Lys Asn Thr Met Ala Leu Met Asp Leu Asp Val Lys Lys Met
  1               5                  10                  15

Pro Leu Gly Lys Leu Ser Lys Gln Gln Ile Ala Arg Gly Phe Glu Ala
             20                  25                  30

Leu Glu Ala Leu Glu Glu Ala Leu Lys Gly Pro Thr Asp Gly Gly Gln
         35                  40                  45

Ser Leu Glu Glu Leu Ser Ser His Phe Tyr Thr Val Ile Pro His Asn
     50                  55                  60

Phe Gly His Ser Gln Pro Pro Pro Ile Asn Ser Pro Glu Leu Leu Gln
 65                  70                  75                  80

Ala Lys Lys Asp Met Leu Leu Val Leu Ala Asp Ile Glu Leu Ala Gln
                 85                  90                  95

Ala Leu Gln Ala Val Ser Glu Gln Glu Lys Thr Val Glu Glu Val Pro
            100                 105                 110

His Pro Leu Asp Arg Asp Tyr Gln Leu Xaa Lys Cys Gln Leu Gln Leu
        115                 120                 125

Leu Asp Ser Gly Ala Pro Glu Tyr Lys Val Ile Gln Asp Leu Leu Xaa
    130                 135                 140

Thr Asp Trp Gln Gln Pro Gln Val Pro Tyr Thr Ser Thr His Leu Glu
145                 150                 155                 160

Ser Lys Pro Xaa Arg Gly Gly Arg Gln Ile 
                165                 170



<210> 1716
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1716
Met Ala Leu Asp Pro Tyr Thr Glu Leu Arg Lys Gln Pro Leu Arg Lys
  1               5                  10                  15

Tyr Val Thr Pro Ser Asp Phe Asp Gln Leu Lys Gln Phe Leu Thr Phe
             20                  25                  30

Asp Lys Gln Val Leu Arg Phe Tyr Ala Ile Trp Asp Asp Thr Asp Ser
         35                  40                  45

Met Tyr Gly Glu Cys Arg Thr Tyr Ile Ile His Tyr Tyr Leu Met Asp
     50                  55                  60

Asp Thr Val Glu Ile Arg Glu Val His Glu Arg Asn Asp Gly Arg Asp
 65                  70                  75                  80

Pro Phe Pro Leu Leu Met Asn Arg Gln Arg Val Pro Lys Val Leu Val
                 85                  90                  95

Glu Asn Ala Lys Glu Leu Pro Ser Val Cys Ala Arg Asn Leu Trp Thr
            100                 105                 110

Lys Glu Val Leu Gly Met Gly Ile Leu Leu Lys Xaa Phe Ile Val Gly
        115                 120                 125

Glu Val Thr His Tyr Ser Leu Gly Glu Leu Ser Ser Ile Tyr Gly Leu
    130                 135                 140

Trp Ile Pro Phe Tyr Ser Asp Gly Xaa Leu Pro Lys Gly Lys Val Trp
145                 150                 155                 160

Asp Ser Leu Asp Phe Xaa Pro Gly 
                165



<210> 1717
<211> 334
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (264)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (309)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1717
Met Ala Ala Val Gly Arg Val Gly Ser Phe Gly Ser Ser Pro Pro Gly
  1               5                  10                  15

Leu Ser Ser Thr Tyr Thr Gly Gly Pro Leu Gly Asn Glu Ile Ala Ser
             20                  25                  30

Gly Asn Gly Gly Ala Ala Ala Gly Asp Asp Glu Asp Gly Gln Asn Leu
         35                  40                  45

Trp Ser Cys Ile Leu Ser Glu Val Ser Thr Arg Ser Arg Ser Lys Leu
     50                  55                  60

Pro Ala Gly Lys Asn Val Leu Leu Leu Gly Glu Asp Gly Ala Gly Lys
 65                  70                  75                  80

Thr Ser Leu Ile Arg Lys Ile Gln Gly Ile Glu Glu Tyr Lys Lys Gly
                 85                  90                  95

Arg Gly Leu Glu Tyr Leu Tyr Leu Asn Val His Asp Glu Asp Arg Asp
            100                 105                 110

Asp Gln Thr Arg Cys Asn Val Trp Ile Leu Asp Gly Asp Leu Tyr His
        115                 120                 125

Lys Gly Leu Leu Lys Phe Ser Leu Asp Ala Val Ser Leu Lys Asp Thr
    130                 135                 140

Leu Val Met Leu Val Val Asp Met Ser Lys Pro Trp Thr Ala Leu Asp
145                 150                 155                 160

Ser Leu Gln Lys Trp Ala Ser Val Val Arg Glu His Val Asp Lys Leu
                165                 170                 175

Lys Ile Pro Pro Glu Glu Met Lys Gln Met Glu Gln Lys Leu Ile Arg
            180                 185                 190

Asp Phe Gln Glu Tyr Val Glu Pro Gly Glu Asp Phe Pro Ala Ser Pro
        195                 200                 205

Gln Arg Arg Asn Thr Ala Ser Gln Glu Asp Lys Asp Asp Ser Val Val
    210                 215                 220

Leu Pro Leu Gly Ala Asp Thr Leu Thr His Asn Leu Gly Ile Pro Val
225                 230                 235                 240

Leu Val Val Cys Thr Lys Cys Asp Ala Ile Ser Val Leu Glu Lys Glu
                245                 250                 255

His Asp Tyr Arg Asp Glu His Xaa Asp Phe Ile Gln Ser His Ile Arg
            260                 265                 270

Lys Phe Cys Leu Xaa Tyr Gly Ala Ala Leu Ile Tyr Thr Ser Val Lys
        275                 280                 285

Glu Asn Lys Asn Ile Asp Leu Val Tyr Lys Tyr Ile Val Gln Lys Leu
    290                 295                 300

Tyr Gly Phe Pro Xaa Lys Ile Pro Ala Val Val Val Glu Lys Asp Ala
305                 310                 315                 320

Val Phe Ile Pro Ala Gly Trp Asp Asn Gly Lys Lys Ile Gly 
                325                 330



<210> 1718
<211> 255
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (246)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1718
Met Val Pro Ser Leu Ala Xaa Phe Asp Asp Ala Thr Leu Gly Phe Leu
  1               5                  10                  15

Xaa Pro Ser Gly Pro Gly Ser Leu Lys Asp Arg Val Leu Gln Met Gln
             20                  25                  30

Arg Asp Ile Arg Gly Ala Arg Pro Glu Pro Arg Phe Gly Ser Val Val
         35                  40                  45

Arg Arg Ala Ala Asn Val Ser Leu Gly Val Leu Leu Ala Trp Leu Ser
     50                  55                  60

Val Pro Val Val Leu Asn Leu Leu Ser Ser Arg Gln Val Met Asn Thr
 65                  70                  75                  80

His Phe Asn Ser Leu His Ile Val Asn Thr Tyr Gly Ala Phe Gly Ser
                 85                  90                  95

Ile Thr Lys Glu Arg Ala Glu Val Ile Leu Gln Gly Thr Ala Ser Ser
            100                 105                 110

Asn Ala Ser Ala Pro Asp Ala Met Trp Glu Asp Tyr Glu Phe Lys Cys
        115                 120                 125

Lys Pro Gly Asp Pro Ser Arg Arg Pro Cys Leu Ile Ser Pro Tyr His
    130                 135                 140

Tyr Arg Leu Asp Trp Leu Met Trp Phe Ala Ala Phe Gln Thr Tyr Glu
145                 150                 155                 160

His Asn Asp Trp Xaa Ile His Leu Ala Gly Lys Leu Leu Ala Ser Asp
                165                 170                 175

Ala Glu Ala Leu Ser Leu Leu Ala His Asn Pro Phe Ala Gly Arg Pro
            180                 185                 190

Pro Pro Arg Trp Val Arg Gly Gly Ala Leu Gln Val Gln Val Gln Pro
        195                 200                 205

Ser Trp Gly Gln Ala Arg Arg Arg Gly Gln Val Val Gly Ala Glu Glu
    210                 215                 220

Gly Ser Glu Pro Tyr Phe Pro Pro Phe Ser Leu Gly Gly Ala Glu Gly
225                 230                 235                 240

Pro Tyr Phe Lys Asp Xaa Gly Trp Ala Phe Cys Pro Gly Pro Phe 
                245                 250                 255



<210> 1719
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1719
Met Gly Asn Ala Ser Phe Gly Ser Lys Glu Gln Lys Leu Leu Lys Arg
  1               5                  10                  15

Leu Arg Leu Leu Pro Ala Leu Leu Ile Leu Arg Ala Phe Lys Pro His
             20                  25                  30

Arg Lys Ile Arg Asp Tyr Arg Val Val Val Val Gly Thr Ala Gly Val
         35                  40                  45

Gly Lys Ser Thr Leu Leu His Lys Trp Ala Ser Gly Asn Phe Arg His
     50                  55                  60

Glu Tyr Leu Pro Thr Ile Glu Asn Thr Tyr Cys Gln Leu Leu Gly Leu
 65                  70                  75                  80

Ala Ala Thr Val Leu Leu Phe Pro Gly Thr Phe Thr Glu Gln Ala Arg
                 85                  90                  95

Val Gly Arg Xaa Ala Asn 
            100



<210> 1720
<211> 313
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (251)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (268)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (288)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (304)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (312)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1720
Met Ala Leu Tyr Ser Ile Ile Gln Tyr Phe Ser Val Thr Leu Leu Tyr
  1               5                  10                  15

Ser Ile Leu Ser Asn Leu Gly Asp Phe Gln Phe Leu Phe Ile Asp Leu
             20                  25                  30

Ala Ile Ile Leu Val Val Val Phe Thr Met Ser Leu Asn Pro Ala Trp
         35                  40                  45

Lys Glu Leu Val Ala Gln Arg Pro Pro Ser Gly Leu Ile Ser Gly Ala
     50                  55                  60

Leu Leu Phe Ser Val Leu Ser Gln Ile Ile Ile Cys Ile Gly Phe Gln
 65                  70                  75                  80

Ser Leu Gly Phe Phe Trp Val Lys Gln Gln Pro Trp Tyr Glu Val Trp
                 85                  90                  95

His Pro Lys Ser Asp Ala Cys Asn Thr Thr Gly Ser Gly Phe Trp Asn
            100                 105                 110

Ser Ser His Val Asp Asn Glu Thr Glu Leu Asp Glu His Asn Ile Gln
        115                 120                 125

Asn Tyr Glu Asn Thr Thr Val Phe Phe Ile Ser Ser Phe Gln Tyr Leu
    130                 135                 140

Ile Val Ala Ile Ala Phe Ser Lys Gly Lys Pro Phe Arg Gln Pro Cys
145                 150                 155                 160

Tyr Lys Asn Tyr Phe Phe Val Phe Ser Val Ile Phe Leu Tyr Ile Phe
                165                 170                 175

Ile Leu Phe Ile Met Leu Tyr Pro Val Ala Ser Val Asp Gln Val Leu
            180                 185                 190

Gln Ile Val Cys Val Pro Tyr Gln Trp Arg Val Thr Met Leu Ile Ile
        195                 200                 205

Val Leu Val Asn Ala Phe Val Ser Ile Thr Val Glu Asn Phe Phe Leu
    210                 215                 220

Asp Met Val Leu Trp Lys Val Val Phe Asn Arg Asp Lys Gln Gly Glu
225                 230                 235                 240

Tyr Arg Phe Ser Thr Thr Gln Pro Pro Gln Xaa Ser Val Asp Arg Trp
                245                 250                 255

Gly Lys Cys Cys Leu Pro Trp Ala Leu Gly Cys Xaa Lys Lys Thr Pro
            260                 265                 270

Lys Ala Lys Tyr Met Tyr Leu Ala Gln Glu Leu Leu Val Asp Pro Xaa
        275                 280                 285

Trp Pro Pro Lys Pro Gln Thr Thr Thr Glu Ala Lys Ala Leu Val Xaa
    290                 295                 300

Glu Asn Gly Ser Cys Gln Ile Xaa Pro 
305                 310



<210> 1721
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1721
Met Val Ser Val Gly Gly Arg Leu Trp Cys Gly Cys Gln Asn Arg Val
  1               5                  10                  15

Leu Val Leu Ser Pro Asp Thr Leu Gln Leu Glu His Met Phe Tyr Val
             20                  25                  30

Gly Gln Asp Ser Ser Arg Cys Val Ala Cys Met Val Asp Ser Ser Leu
         35                  40                  45

Gly Val Trp Val Thr Leu Lys Gly Ser Ala His Val Cys Leu Tyr His
     50                  55                  60

Pro Asp Thr Phe Glu Gln Leu Ala Glu Val Asp Val Thr Pro Pro Val
 65                  70                  75                  80

His Arg Met Leu Ala Ser Ser Asp Ala Ile Ile Arg Gln His Lys Ala
                 85                  90                  95

Ala Cys Leu Arg Ile Thr Ala Leu Leu Val Cys Xaa Glu Leu Leu Trp
            100                 105                 110

Val Gly Thr Xaa Ala Gly Val 
        115



<210> 1722
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1722
Met Gly Gly Leu Glu Arg Ile Tyr His Ser Trp Cys Glu Gly Tyr Ser
  1               5                  10                  15

Thr Cys Arg Asn Gly Gly His Arg Ser Gly Pro Arg Ile Gly Val Val
             20                  25                  30

Lys Val Ala Arg Val Pro Leu Lys Tyr Leu Asn Thr Leu Cys Cys Xaa
         35                  40                  45

Val Thr Val Glu Pro Cys Ile Met Cys Ala Thr Ala Leu Arg Leu Met
     50                  55                  60

Lys Ile Pro Leu Val Val Tyr Gly Cys Gln Asn Glu Arg Phe Gly Gly
 65                  70                  75                  80

Cys Gly Ser Val Leu Asn Ile Ala Ser Ala Asp Leu Pro Asn Thr Gly
                 85                  90                  95

Arg Pro Phe Gln Cys Ile Pro Gly Tyr Arg Ala Glu Glu Ala Val Glu
            100                 105                 110

Xaa Leu Lys Thr 
        115



<210> 1723
<211> 242
<212> PRT
<213> Homo sapiens

<400> 1723
Met Leu His Ser Asn Cys Pro Lys Gly Leu Leu Pro Lys Phe Ser Ser
  1               5                  10                  15

Trp Ser Leu Val Lys Leu Gly Pro Ala Lys Ser Tyr Asn Phe His Thr
             20                  25                  30

Gly Leu Asp Gln Gln Gly Phe Ile Pro Gly Thr Asn Tyr Leu Met Pro
         35                  40                  45

Trp Asp Ile Val Ile Arg Thr Arg Ala Glu Asp Glu Gly Asp Leu Asp
     50                  55                  60

Thr Asn Ser Trp Pro Ala Pro Asn Lys Ala Ile Pro Gly Lys Arg Ser
 65                  70                  75                  80

Ala Val Val Met Gly Arg Gly Arg Arg Arg Asp Asp Ile Ala Arg Ala
                 85                  90                  95

Phe Val Gly Phe Glu Tyr Glu Asp Ser Arg Gly Arg Arg Phe Met Cys
            100                 105                 110

Ser Gly Pro Asp Lys Val Met Lys Val Met Gly Ser Gly Pro Lys Glu
        115                 120                 125

Ser Ala Leu Lys Ala Leu Asn Ser Asp Met Pro Leu Tyr Ile Leu Ser
    130                 135                 140

Ser Ser Gln Gly Arg Gly Leu Lys Pro His Tyr Ala Gln Leu Met Arg
145                 150                 155                 160

Leu Phe Val Val Val Pro Asp Ala Pro Leu Gln Ile Ile Leu Met Pro
                165                 170                 175

Gln Val Gln Pro Gly Pro Pro Pro Cys Pro Val Phe Tyr Pro Glu Lys
            180                 185                 190

Gln Glu Ile Thr Leu Pro Pro Asp Gly Leu Trp Val Leu Arg Phe Pro
        195                 200                 205

Tyr Ala Tyr Val Thr Glu Arg Gly Pro Cys Phe Pro Pro Lys Glu Asn
    210                 215                 220

Val Gln Leu Met Ser Tyr Lys Val Leu Arg Gly Val Leu Lys Ala Val
225                 230                 235                 240

Thr Gln 




<210> 1724
<211> 169
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1724
Met Trp Glu Asn Leu Ile Thr Pro Pro Cys Ser Asn Leu Asn Gly Asn
  1               5                  10                  15

Gly Ser Gly Lys Gln Met Pro Pro Cys His Arg Val Thr Glu Gly Pro
             20                  25                  30

Arg Val Met Leu Ser His Ser Ile Asn Asn Ile Phe Arg Val Val Thr
         35                  40                  45

Thr Gly Ser Leu Leu Ala Arg Arg Gly Lys Arg Leu Trp Arg Ser Arg
     50                  55                  60

Ala Gln Cys Pro Lys Pro Gln Ala Gly Ile Gly His Pro Ile Val Pro
 65                  70                  75                  80

Arg Leu Ala Ser Pro Leu Leu Thr Ser Tyr Trp Glu Asn Ser Val Ala
                 85                  90                  95

Pro Lys Cys Lys Gly Arg Trp Glu Val Gln Ser Thr Trp Gly Pro Arg
            100                 105                 110

Lys Lys Gly Arg Val Asn Gly Pro His Thr Ala Val Phe Ala Thr Ser
        115                 120                 125

Cys Leu Phe Leu Ser Xaa Pro Val His Leu Gly Ile Xaa Pro Leu Xaa
    130                 135                 140

Leu Gly Phe Leu Asn Phe Leu Ala Gly Ile Phe Ser Ser Trp Val Thr
145                 150                 155                 160

Phe His Leu Pro Cys Phe Met Pro Ser 
                165



<210> 1725
<211> 463
<212> PRT
<213> Homo sapiens

<400> 1725
Met Ala Asp Gly Glu Glu Pro Glu Lys Lys Arg Arg Arg Ile Glu Glu
  1               5                  10                  15

Leu Leu Ala Glu Lys Met Ala Val Asp Gly Gly Cys Gly Asp Thr Gly
             20                  25                  30

Asp Trp Glu Gly Arg Trp Asn His Val Lys Lys Phe Leu Glu Arg Ser
         35                  40                  45

Gly Pro Phe Thr His Pro Asp Phe Glu Pro Ser Thr Glu Ser Leu Gln
     50                  55                  60

Phe Leu Leu Asp Thr Cys Lys Val Leu Val Ile Gly Ala Gly Gly Leu
 65                  70                  75                  80

Gly Cys Glu Leu Leu Lys Asn Leu Ala Leu Ser Gly Phe Arg Gln Ile
                 85                  90                  95

His Val Ile Asp Met Asp Thr Ile Asp Val Ser Asn Leu Asn Arg Gln
            100                 105                 110

Phe Leu Phe Arg Pro Lys Asp Ile Gly Arg Pro Lys Ala Glu Val Ala
        115                 120                 125

Ala Glu Phe Leu Asn Asp Arg Val Pro Asn Cys Asn Val Val Pro His
    130                 135                 140

Phe Asn Lys Ile Gln Asp Phe Asn Asp Thr Phe Tyr Arg Gln Phe His
145                 150                 155                 160

Ile Ile Val Cys Gly Leu Asp Ser Ile Ile Ala Arg Arg Trp Ile Asn
                165                 170                 175

Gly Met Leu Ile Ser Leu Leu Asn Tyr Glu Asp Gly Val Leu Asp Pro
            180                 185                 190

Ser Ser Ile Val Pro Leu Ile Asp Gly Gly Thr Glu Gly Phe Lys Gly
        195                 200                 205

Asn Ala Arg Val Ile Leu Pro Gly Met Thr Ala Cys Ile Glu Cys Thr
    210                 215                 220

Leu Glu Leu Tyr Pro Pro Gln Val Asn Phe Pro Met Cys Thr Ile Ala
225                 230                 235                 240

Ser Met Pro Arg Leu Pro Glu His Cys Ile Glu Tyr Val Arg Met Leu
                245                 250                 255

Gln Trp Pro Lys Glu Gln Pro Phe Gly Glu Gly Val Pro Leu Asp Gly
            260                 265                 270

Asp Asp Pro Glu His Ile Gln Trp Ile Phe Gln Lys Ser Leu Glu Arg
        275                 280                 285

Ala Ser Gln Tyr Asn Ile Arg Gly Val Thr Tyr Arg Leu Thr Gln Gly
    290                 295                 300

Val Val Lys Arg Ile Ile Pro Ala Val Ala Ser Thr Asn Ala Val Ile
305                 310                 315                 320

Ala Ala Val Cys Ala Thr Glu Val Phe Lys Ile Ala Thr Ser Ala Tyr
                325                 330                 335

Ile Pro Leu Asn Asn Tyr Leu Val Phe Asn Asp Val Asp Gly Leu Tyr
            340                 345                 350

Thr Tyr Thr Phe Glu Ala Glu Arg Lys Glu Asn Cys Pro Ala Cys Ser
        355                 360                 365

Gln Leu Pro Gln Asn Ile Gln Phe Ser Pro Ser Ala Lys Leu Gln Glu
    370                 375                 380

Val Leu Asp Tyr Leu Thr Asn Ser Ala Ser Leu Gln Met Lys Ser Pro
385                 390                 395                 400

Ala Ile Thr Ala Thr Leu Glu Gly Lys Asn Arg Thr Leu Tyr Leu Gln
                405                 410                 415

Ser Val Thr Ser Ile Glu Glu Arg Thr Arg Pro Asn Leu Ser Lys Thr
            420                 425                 430

Leu Lys Glu Leu Gly Leu Val Asp Gly Gln Glu Leu Ala Val Ala Asp
        435                 440                 445

Val Thr Thr Pro Gln Thr Val Leu Phe Lys Leu His Phe Thr Ser 
    450                 455                 460



<210> 1726
<211> 171
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (169)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1726
Met Phe Lys Gln Leu Phe Gln Lys Trp Ser Val Lys Asp Gln Thr Met
  1               5                  10                  15

Gly Leu Gly Lys Thr Phe Ser Ile Gly Lys Ile Ala Lys Val Phe Gln
             20                  25                  30

Asp Lys Phe Asp Val Thr Leu Leu His Thr Lys Pro Glu Val Ala Ala
         35                  40                  45

Gln Glu Arg Met Val Asp Asp Gly Asn Gly Lys Val Glu Val Trp Arg
     50                  55                  60

Ile Glu Asn Leu Glu Leu Val Pro Val Glu Tyr Gln Trp Tyr Gly Phe
 65                  70                  75                  80

Phe Tyr Gly Gly Asp Cys Tyr Leu Val Leu Tyr Thr Tyr Glu Val Asn
                 85                  90                  95

Gly Lys Pro His His Ile Leu Tyr Ile Trp Gln Val Gly Leu Ala Gln
            100                 105                 110

Leu Xaa Leu Trp Ile Leu Met Cys Pro Leu Ala Thr Gly Leu Gly Arg
        115                 120                 125

Gly Ala Trp Val Leu His Gly Leu Ser Pro Leu Gln Gly Arg His Ala
    130                 135                 140

Ser Gln Asp Glu Leu Ala Ala Ser Ala Tyr Gln Ala Val Glu Val Asp
145                 150                 155                 160

Xaa Gln Phe Asp Xaa Ala Ala Val Xaa Val Arg 
                165                 170



<210> 1727
<211> 222
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1727
Met Met Gly Asn Met Glu Leu Ala Glu Gln Leu Lys Val Gln Leu Glu
  1               5                  10                  15

Lys Ala Asn Lys Phe Lys Glu Thr Ile Thr Gln Ile Pro Lys Lys Ser
             20                  25                  30

Gly Val Glu Asn Glu Asp Gln Gln Glu Val Xaa Leu Val Arg Thr Asp
         35                  40                  45

Gln Ser Gly Arg Val Trp Pro Val Asn Thr Pro Gly Lys Ser Leu Glu
     50                  55                  60

Ser Gln Gly Gly Arg Arg Lys Arg Gln Met Val Ser Thr His Glu Glu
 65                  70                  75                  80

Arg Glu Arg Val Arg Tyr Phe His Asp Asp Asp Asn Leu Ser Leu Asn
                 85                  90                  95

Asp Leu Val Lys Asn Glu Lys Met Gly Thr Ala Glu Asn Gln Asn Lys
            100                 105                 110

Leu Phe Met Arg Met Ala Ser Lys Phe Met Gly Lys Thr Asp Gly Asp
        115                 120                 125

Tyr Tyr Thr Leu Asp Asp Met Phe Val Ser Lys Ala Ala Glu Arg Glu
    130                 135                 140

Arg Leu Gly Glu Glu Glu Glu Asn Gln Arg Lys Lys Ala Ile Ala Glu
145                 150                 155                 160

His Arg Ser Leu Ala Ala Gln Met Glu Lys Cys Leu Tyr Cys Phe Asp
                165                 170                 175

Ser Ser Gln Phe Pro Lys His Leu Ile Val Ala Ile Gly Val Lys Val
            180                 185                 190

Tyr Leu Cys Leu Pro Asn Val Arg Ser Leu Thr Glu Gly His Cys Leu
        195                 200                 205

Ile Val Pro Leu Gln His His Arg Ala Ala Thr Leu Leu Gly 
    210                 215                 220



<210> 1728
<211> 101
<212> PRT
<213> Homo sapiens

<400> 1728
Met Ala Ile Ala Leu Trp Asn Asn Met Leu Glu Pro Val Gly Arg Lys
  1               5                  10                  15

Thr Thr Ser Asn Asn Phe Thr His Ser Arg Ala Lys Leu Lys Cys Pro
             20                  25                  30

Ser Pro Glu Ser Pro Tyr Leu Tyr Thr Leu Arg Asn Ser Arg Leu Leu
         35                  40                  45

Pro Asp Gln Ala Glu Glu Ala Pro Glu Val Leu Tyr Trp Ala Val Pro
     50                  55                  60

Val Ala Ala Gly Val Gly Leu Val Val Gly Ile Ile Gly Thr Val Val
 65                  70                  75                  80

Trp Arg Cys Arg Arg Gly Gly Arg Arg Glu Asp Pro Pro Met Ser Leu
                 85                  90                  95

Arg Thr Gly Ala Leu 
            100



<210> 1729
<211> 190
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1729
Met Ala Ser Ala Gly Gly Glu Asp Cys Glu Ser Pro Ala Pro Glu Ala
  1               5                  10                  15

Asp Arg Pro His Gln Arg Pro Phe Leu Ile Gly Val Ser Gly Gly Thr
             20                  25                  30

Xaa Ser Gly Lys Ser Thr Val Cys Glu Lys Ile Met Glu Leu Leu Gly
         35                  40                  45

Gln Asn Glu Val Glu Gln Arg Gln Arg Lys Val Val Ile Leu Ser Gln
     50                  55                  60

Asp Arg Phe Tyr Lys Val Leu Thr Ala Glu Gln Lys Ala Lys Ala Leu
 65                  70                  75                  80

Lys Gly Gln Tyr Asn Phe Asp His Pro Asp Ala Phe Asp Asn Asp Leu
                 85                  90                  95

Met His Arg Thr Leu Lys Asn Ile Val Glu Gly Lys Thr Val Glu Val
            100                 105                 110

Pro Thr Tyr Asp Phe Val Thr His Ser Arg Leu Pro Glu Thr Thr Val
        115                 120                 125

Val Tyr Pro Ala Asp Val Val Leu Phe Glu Gly Ile Leu Val Phe Tyr
    130                 135                 140

Ser Gln Glu Ile Arg Asp Met Phe His Leu Arg Leu Phe Val Asp Thr
145                 150                 155                 160

Asp Ser Asp Val Arg Leu Ser Arg Arg Xaa Leu Arg Asp Val Arg Arg
                165                 170                 175

Gly Arg Asp Leu Glu Gln Ile Leu Thr His Thr Pro Pro Ser 
            180                 185                 190



<210> 1730
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1730
Met Ser Glu Pro Gln Pro Arg Gly Ala Glu Arg Asp Leu Tyr Arg Asp
  1               5                  10                  15

Thr Trp Val Arg Tyr Leu Gly Tyr Ala Asn Glu Val Gly Glu Ala Phe
             20                  25                  30

Arg Ser Leu Val Pro Ala Ala Val Val Trp Leu Ser Tyr Gly Val Ala
         35                  40                  45

Ser Ser Tyr Val Leu Ala Asp Ala Ile Asp Lys Gly Lys Lys Ala Gly
     50                  55                  60

Glu Val Pro Ser Pro Glu Ala Gly Arg Ser Ala Arg Val Thr Val Ala
 65                  70                  75                  80

Val Val Asp Thr Phe Val Trp Gln Ala Leu Ala Ser Val Ala Ile Pro
                 85                  90                  95

Gly Phe Thr Ile Asn Arg Val Cys Ala Ala Ser Leu Tyr Val Leu Gly
            100                 105                 110

Thr Ala Thr Arg Trp Pro Leu Ala Val Arg Lys Trp Thr Thr Thr Ala
        115                 120                 125

Leu Gly Leu Leu Thr Ile Pro Ile Ile Ile His Pro Ile Asp Arg Ser
    130                 135                 140

Val Asp Phe Leu Leu Asp Ser Ser Leu Arg Xaa Xaa Tyr Pro Thr Val
145                 150                 155                 160

Gly Lys Pro Ser Ser Ser 
                165



<210> 1731
<211> 121
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1731
Met Leu Lys Asp Ile Ile Lys Glu Tyr Thr Asp Val Tyr Pro Glu Ile
  1               5                  10                  15

Ile Glu Arg Ala Gly Tyr Ser Leu Glu Lys Val Phe Gly Ile Gln Leu
             20                  25                  30

Lys Glu Ile Asp Lys Asn Asp His Leu Tyr Ile Leu Leu Ser Thr Leu
         35                  40                  45

Xaa Pro Thr Asp Ala Gly Ile Leu Gly Thr Thr Lys Asp Ser Pro Lys
     50                  55                  60

Leu Gly Leu Leu Met Val Leu Leu Asn Ile Ile Phe Met Asn Gly Asn
 65                  70                  75                  80

Arg Ser Ser Glu Ala Val Ile Trp Glu Val Leu Arg Xaa Leu Gly Leu
                 85                  90                  95

Ala Pro Trp Val Met Ile Gly Ala Leu Ser Xaa Leu Gly Val Arg Val
            100                 105                 110

Val Xaa Leu Gly Lys Lys Arg Xaa Ser 
        115                 120



<210> 1732
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1732
Met Trp Pro Pro His Arg Thr Leu Val Thr Trp Ala Leu Arg Leu Lys
  1               5                  10                  15

Arg Pro Leu Pro Arg Arg Ser Trp Pro Ala Gly Ala Ser Pro Ala Thr
             20                  25                  30

Thr Leu Asn Thr Cys Cys Val Trp Gln Thr Ser Cys Ser Ser Val Gly
         35                  40                  45

Leu Arg Arg Arg Thr Ser Thr Trp Gln Pro Ser Trp Thr Leu Trp Ala
     50                  55                  60

Pro Cys Cys Pro Ala Ser Ala Pro Pro Ser Xaa Leu Trp Arg Trp Cys
 65                  70                  75                  80

Glu Gly Leu Ser Pro Cys Gly Glu Cys Ser Cys Gly His Gln Gly Gln
                 85                  90                  95

Thr Pro Thr Pro Val His Lys Thr Asp Cys Asp Arg Leu Ser Pro Leu
            100                 105                 110

Ser Xaa Tyr Gly Gly Trp Leu Glu Ala Ser Leu Ser Gln Ser Leu Pro
        115                 120                 125

Val Cys Gln Pro Ala Ala Leu Leu Leu Asp Thr Asp Leu Leu Leu Glu
    130                 135                 140

Thr Leu Phe Ile Ala Pro Cys Trp Cys Gly Gly Gln Val Glu Gly Leu
145                 150                 155                 160

Pro Trp Thr Gln Gly Pro Cys 
                165



<210> 1733
<211> 137
<212> PRT
<213> Homo sapiens

<400> 1733
Met Arg Pro Gln Gln Ala Pro Val Ser Gly Lys Val Phe Ile Gln Arg
  1               5                  10                  15

Asp Tyr Ser Ser Gly Thr Arg Cys Gln Phe Gln Thr Lys Phe Pro Ala
             20                  25                  30

Glu Leu Glu Asn Arg Ile Asp Arg Gln Gln Phe Glu Glu Thr Val Arg
         35                  40                  45

Thr Leu Asn Asn Leu Tyr Ala Glu Ala Glu Lys Leu Gly Gly Gln Ser
     50                  55                  60

Tyr Leu Glu Gly Cys Leu Ala Cys Leu Thr Ala Tyr Thr Ile Phe Leu
 65                  70                  75                  80

Cys Met Glu Thr His Tyr Glu Lys Val Leu Lys Lys Val Ser Lys Tyr
                 85                  90                  95

Ile Gln Glu Gln Asn Glu Lys Ile Tyr Ala Pro Gln Gly Leu Leu Leu
            100                 105                 110

Thr Asp Pro Ile Glu Arg Gly Leu Arg Val Ile Glu Ile Thr Ile Tyr
        115                 120                 125

Glu Asp Arg Gly Met Ser Ser Gly Arg 
    130                 135



<210> 1734
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1734
Met Phe Leu Ser Ser Val Leu Ile Val Leu Leu Ser Cys Pro Lys Met
  1               5                  10                  15

Lys Pro Phe His Val Phe Ser Leu Lys Ile Ile Phe Ser Glu Met Glu
             20                  25                  30

Cys Cys Arg Val Ala Gln Ala Gly Leu Asn Leu Leu Gly Thr Ser Asn
         35                  40                  45

Leu Pro Pro Ser Ala Ser Gln Val Ala Gly Thr Ile Gly Thr Cys Tyr
     50                  55                  60

Pro Ala Ser Ser Phe Cys Met Val Ile Phe Phe Cys Pro Leu Trp Arg
 65                  70                  75                  80

Val Phe Phe Phe Leu Arg Gln Ser Arg Ser Val Thr Gln Ala Gly Glu
                 85                  90                  95

Gln Trp His Asn Leu Ser Ser Leu Xaa Pro Leu Pro Leu Gly Phe Lys
            100                 105                 110

Xaa Phe Leu Xaa Leu Ser Tyr 
        115



<210> 1735
<211> 126
<212> PRT
<213> Homo sapiens

<400> 1735
Met Glu Val Gln Ala Pro Pro Gly Thr Thr Ile Gly His Val Leu Gln
  1               5                  10                  15

Thr Trp His Pro Phe Leu Pro Lys Phe Ser Ile Gln Asp Ala Asp Arg
             20                  25                  30

Gln Thr Val Leu Arg Val Val Gly Pro Cys Trp Thr Cys Gly Cys Gly
         35                  40                  45

Thr Asp Thr Asn Phe Glu Val Lys Thr Arg Asp Glu Ser Arg Ser Val
     50                  55                  60

Gly Arg Ile Ser Lys Gln Trp Gly Gly Leu Val Arg Glu Ala Leu Thr
 65                  70                  75                  80

Asp Ala Asp Asp Phe Gly Leu Gln Phe Pro Leu Asp Leu Asp Val Arg
                 85                  90                  95

Val Lys Ala Val Leu Leu Gly Ala Thr Phe Leu Ile Asp Tyr Met Phe
            100                 105                 110

Phe Glu Lys Arg Gly Gly Ala Gly Pro Ser Ala Ile Thr Ser 
        115                 120                 125



<210> 1736
<211> 129
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1736
Met Val Thr Pro Ala Gly Cys Leu Glu Gly Glu Asn Gln Gly Pro Arg
  1               5                  10                  15

Lys Ile Pro Asp Thr Ala Phe Pro Pro Ser Ser Arg Ala Gly Gln Thr
             20                  25                  30

Arg Gln Val Val Ser Gly Ala Gln Val Ser Ser Trp Arg Glu Cys Gln
         35                  40                  45

Pro Cys Ser Gly Ser Pro Ser Cys Ile Leu Gly Thr Asp Ala Asn Val
     50                  55                  60

Gly Xaa Ala Val Ser Trp Val Trp Tyr Pro Phe Leu Ala Ser Glu Arg
 65                  70                  75                  80

Ser Gln Thr Arg Ser Phe Leu Gln Asn Glu Thr Ser Phe Pro Ser Arg
                 85                  90                  95

Ser Thr Ala Asp Cys Leu Val Val Ala Val Arg Ala Val Ser Leu Leu
            100                 105                 110

Ser Ile Leu Arg Xaa Gly Trp Phe Leu Leu Leu Gly Leu Ala Tyr Arg
        115                 120                 125

Pro 




<210> 1737
<211> 306
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (148)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1737
Met Xaa Ala Val Asp Asp Leu Gln Phe Glu Glu Phe Gly Asn Ala Ala
  1               5                  10                  15

Thr Ser Leu Thr Ala Asn Pro Asp Ala Thr Thr Val Asn Ile Glu Asp
             20                  25                  30

Pro Gly Glu Thr Pro Lys His Gln Pro Gly Ser Pro Arg Gly Ser Gly
         35                  40                  45

Arg Glu Glu Asp Asp Glu Leu Leu Gly Asn Asp Asp Ser Asp Lys Thr
     50                  55                  60

Glu Leu Leu Ala Gly Gln Lys Lys Ser Ser Pro Phe Trp Thr Phe Glu
 65                  70                  75                  80

Tyr Tyr Gln Thr Phe Phe Asp Val Asp Thr Tyr Gln Val Phe Asp Arg
                 85                  90                  95

Ile Lys Gly Ser Leu Leu Pro Ile Pro Gly Lys Asn Phe Val Arg Leu
            100                 105                 110

Tyr Ile Arg Ser Asn Pro Asp Leu Tyr Gly Pro Phe Trp Ile Cys Ala
        115                 120                 125

Thr Leu Val Phe Ala Ile Ala Ile Ser Gly Asn Leu Ser Asn Phe Leu
    130                 135                 140

Ile His Leu Xaa Glu Lys Thr Tyr His Tyr Val Pro Glu Phe Arg Lys
145                 150                 155                 160

Val Ser Ile Ala Ala Thr Ile Ile Tyr Ala Tyr Ala Trp Leu Val Pro
                165                 170                 175

Leu Ala Leu Trp Gly Phe Leu Met Trp Xaa Asn Ser Lys Val Met Asn
            180                 185                 190

Ile Val Ser Tyr Ser Phe Leu Glu Ile Val Cys Val Tyr Gly Tyr Ser
        195                 200                 205

Leu Phe Ile Tyr Ile Pro Thr Ala Ile Leu Trp Ile Ile Pro Gln Lys
    210                 215                 220

Ala Val Arg Trp Ile Leu Val Met Ile Ala Leu Gly Ile Ser Gly Ser
225                 230                 235                 240

Leu Leu Ala Met Thr Phe Trp Pro Ala Val Arg Glu Asp Asn Arg Arg
                245                 250                 255

Val Ala Leu Ala Thr Ile Val Thr Ile Val Leu Leu His Met Leu Leu
            260                 265                 270

Ser Val Gly Cys Leu Ala Tyr Phe Phe Asp Ala Pro Glu Met Asp His
        275                 280                 285

Leu Pro Thr Thr Thr Ala Thr Pro Asn Gln Thr Val Ala Ala Ala Lys
    290                 295                 300

Ser Ser 
305



<210> 1738
<211> 100
<212> PRT
<213> Homo sapiens

<400> 1738
Met Glu Lys Leu Glu Leu His Arg Gly Gly Gly Arg Ser Arg Thr Ser
  1               5                  10                  15

Gly Ser Pro Gly Leu Ile Ala Val Ala Gly Ala Arg Ile Trp Val Gln
             20                  25                  30

Asn Arg Val Asp Leu Ser Gln Asn Gly Asn Leu Ile Met Val Ala Val
         35                  40                  45

Thr Leu Val Leu Gly Ala Gly Asp Phe Ala Leu Thr Leu Gly Gly Phe
     50                  55                  60

Thr Leu Gly Gly Ile Gly Thr Ala Thr Phe Gly Ala Ile Leu Leu Asn
 65                  70                  75                  80

Ala Leu Leu Ser Arg Lys Leu Val Asp Val Pro Pro Pro Glu Val Val
                 85                  90                  95

His Gln Glu Pro 
            100



<210> 1739
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1739
Met Phe Glu Gln Glu Asn Gln Arg Leu Ile Gly Glu Met Asn Ser Leu
  1               5                  10                  15

Phe Asp Glu Val Arg Gln Ile Glu Gly Arg Val Val Glu Ile Ser Arg
             20                  25                  30

Leu Gln Glu Ile Phe Thr Glu Lys Val Leu Gln Gln Glu Ala Glu Ile
         35                  40                  45

Xaa Ser Ile His Gln Leu Val Val Gly Ala Thr Xaa Asn Ile Lys Glu
     50                  55                  60

Gly Asn Glu Asp Ile Arg Glu Ala Ile Lys Asn Asn Ala Gly Phe Arg
 65                  70                  75                  80

Val Trp Ile Leu Phe Phe Leu Val Met Cys Ser Phe Ser Leu Leu Phe
                 85                  90                  95

Leu Asp Trp Tyr Asp Ser 
            100



<210> 1740
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1740
Met Arg Asn Xaa Gly Asp Phe His Gln Arg Val Arg Phe Tyr Gln Ser
  1               5                  10                  15

Ala Leu Asn Ala Glu Ser Arg Arg Xaa Ile Thr Arg Lys Lys Leu Gly
             20                  25                  30

Val Asp Phe Val Asn Arg Gly Val Ile Phe Pro Val Gly Asn Lys Asp
         35                  40                  45

Ala Val Glu Gly His Ile Arg His Arg Ala Thr Arg Arg Leu Asp His
     50                  55                  60

Leu Ala Asp Ser Phe Gln Asn Val Ala Gly Leu Arg Leu Trp Val Ile
 65                  70                  75                  80

Gly Lys Gln His Val Ile Met Leu Ile Lys Ser Gln Arg Thr Gly Asp
                 85                  90                  95

Ile His His Ala Ile Ser Gln Arg Ala Gly Asn Glu Gly Gly Gln Arg
            100                 105                 110

Cys Leu Leu Pro Ala Gly Ile Ile Thr Asp Phe Gly Ile Val Lys Leu
        115                 120                 125

Leu Lys Arg Tyr Glu Gln Arg Thr Trp Glu Lys Ser Ala Ser Gln Asn
    130                 135                 140

Val Ser Thr 
145



<210> 1741
<211> 197
<212> PRT
<213> Homo sapiens

<400> 1741
Met Gln Leu Val Gln Ser Trp Pro Gly Pro Pro Arg Asn Thr Pro Gly
  1               5                  10                  15

Pro Pro Trp Ser Gly Asp Leu Arg Ile Gly Arg Arg Phe Arg Glu Gln
             20                  25                  30

Pro Leu Leu Phe Glu Leu Leu Lys Leu Val Ala Ala Ala Pro Pro Ala
         35                  40                  45

Leu Cys Tyr Cys Ser Val Leu Leu Arg Gly Leu Leu Ala Ala Leu Leu
     50                  55                  60

Gly His Trp Glu Ala Ser Arg His Pro Asp Thr Thr His Ser Pro Trp
 65                  70                  75                  80

His Leu Glu Ala Ser Cys Thr Leu Val Ala Val Met Ala Glu Gly Ser
                 85                  90                  95

Leu Leu Pro Pro Ala Leu Gly Asn Met His Glu Val Phe Ser Gln Leu
            100                 105                 110

Ala Pro Phe Glu Val Arg Leu Leu Leu Leu Ser Val Trp Gly Phe Leu
        115                 120                 125

Arg Glu His Gly Pro Leu Pro Gln Lys Phe Ile Phe Gln Ser Glu Arg
    130                 135                 140

Gly Arg Phe Ile Arg Asp Phe Ser Arg Glu Gly Gly Gly Glu Gly Gly
145                 150                 155                 160

Pro His Leu Ala Val Leu His Ser Val Leu His Arg Asn Ile Asp Arg
                165                 170                 175

Leu Gly Leu Phe Ser Gly Arg Phe Gln Ala Pro Ser Pro Ser Thr Leu
            180                 185                 190

Leu Arg Gln Gly Thr 
        195



<210> 1742
<211> 157
<212> PRT
<213> Homo sapiens

<400> 1742
Met Gln Ala Glu Gly Asp Pro Pro Trp Pro Thr Pro Arg Ser Pro Ala
  1               5                  10                  15

Glu Ala Pro Thr Arg Arg Lys Arg Leu Thr Thr Ala Arg Ser Ala Glu
             20                  25                  30

Ser Glu Ser Trp Asp His Leu Val Leu Gln Gly Asp Pro Arg Leu Pro
         35                  40                  45

Arg Thr Gly Glu Arg Asp Arg Pro His Ser Asp Ser Ser Trp Gly Leu
     50                  55                  60

Cys Thr Gly Phe Ser Leu Gly Gly Val Ala Cys Tyr Ile Ala Val Pro
 65                  70                  75                  80

Gln Arg Lys Gly Pro Ala Phe Ser Gly Met Phe Ser Val Leu Thr Pro
                 85                  90                  95

Leu Cys Ala Pro Pro Leu Leu Leu Tyr Lys Gln Leu Gly Asp Ser Lys
            100                 105                 110

Glu Gln Leu Arg Leu Gly Ala Val Thr His Thr Arg Asn Pro Gly Thr
        115                 120                 125

Leu Gly Gly Arg Gly Gly Gln Gly Gln Glu Phe Lys Thr Ser Leu Ala
    130                 135                 140

Asn Met Val Lys Pro Cys Leu Tyr Lys Lys Tyr Lys Asn 
145                 150                 155



<210> 1743
<211> 119
<212> PRT
<213> Homo sapiens

<400> 1743
Met Asp Ser Pro Ile Ser Phe Lys Phe Pro Lys Ile Lys Lys Ile Pro
  1               5                  10                  15

Thr Met Tyr Gly Leu Leu Cys Gln Phe Leu Pro Leu His Ser Gln Leu
             20                  25                  30

Trp Leu Leu Lys Ser Ser Gln Gln Ile Ala Gln Leu Cys Leu Met Pro
         35                  40                  45

Glu Ser Leu Arg Phe Arg Pro Gly Gly Ile Leu Glu Thr Asn Ser Pro
     50                  55                  60

Pro Ala Gly Ile Arg Lys Leu Val Cys Ser Pro Met Pro Gly Val Ser
 65                  70                  75                  80

Ser Pro Lys Asp Tyr Ile Ser Phe Lys Leu Ser Phe Leu Ser Leu Thr
                 85                  90                  95

Thr Leu Pro Leu Leu Pro Ser Ala Phe Leu Phe His Ser Ser Glu Leu
            100                 105                 110

Pro Ala Leu Leu Gly Pro Leu 
        115



<210> 1744
<211> 259
<212> PRT
<213> Homo sapiens

<400> 1744
Met Ser Ser Thr Ser Ser Lys Arg Ala Pro Thr Thr Ala Thr Gln Arg
  1               5                  10                  15

Leu Lys Gln Asp Tyr Leu Arg Ile Lys Lys Asp Pro Val Pro Tyr Ile
             20                  25                  30

Cys Ala Glu Pro Leu Pro Ser Asn Ile Leu Glu Trp His Tyr Val Val
         35                  40                  45

Arg Gly Pro Glu Met Thr Pro Tyr Glu Gly Gly Tyr Tyr His Gly Lys
     50                  55                  60

Leu Ile Phe Pro Arg Glu Phe Pro Phe Lys Pro Pro Ser Ile Tyr Met
 65                  70                  75                  80

Ile Thr Pro Asn Gly Arg Phe Lys Cys Asn Thr Arg Leu Cys Leu Ser
                 85                  90                  95

Ile Thr Asp Phe His Pro Asp Thr Trp Asn Pro Ala Trp Ser Val Ser
            100                 105                 110

Thr Ile Leu Thr Gly Leu Leu Ser Phe Met Val Glu Lys Gly Pro Thr
        115                 120                 125

Leu Gly Ser Ile Glu Thr Ser Asp Phe Thr Lys Arg Gln Leu Ala Val
    130                 135                 140

Gln Ser Leu Ala Phe Asn Leu Lys Asp Lys Val Phe Cys Glu Leu Phe
145                 150                 155                 160

Pro Glu Val Val Glu Glu Ile Lys Gln Lys Gln Lys Ala Gln Asp Glu
                165                 170                 175

Leu Ser Ser Arg Pro Gln Thr Leu Pro Leu Pro Asp Val Val Pro Asp
            180                 185                 190

Gly Glu Thr His Leu Val Gln Asn Gly Ile Gln Leu Leu Asn Gly His
        195                 200                 205

Ala Pro Gly Ala Val Pro Asn Leu Ala Gly Leu Gln Gln Ala Asn Arg
    210                 215                 220

His His Gly Leu Leu Gly Gly Ala Leu Ala Asn Leu Phe Val Ile Val
225                 230                 235                 240

Gly Phe Ala Ala Phe Ala Tyr Thr Val Lys Tyr Val Leu Arg Ser Ile
                245                 250                 255

Ala Gln Glu 




<210> 1745
<211> 173
<212> PRT
<213> Homo sapiens

<400> 1745
Met Ala Pro Lys Gly Lys Ala Gly Thr Arg Gly Lys Lys Gln Ile Phe
  1               5                  10                  15

Glu Glu Asn Arg Glu Thr Leu Lys Phe Tyr Leu Arg Ile Ile Leu Gly
             20                  25                  30

Ala Asn Ala Ile Tyr Cys Leu Val Thr Leu Val Phe Phe Tyr Ser Ser
         35                  40                  45

Ala Ser Phe Trp Ala Trp Leu Ala Leu Gly Phe Ser Leu Ala Val Tyr
     50                  55                  60

Gly Ala Ser Tyr His Ser Met Ser Ser Met Ala Arg Ala Ala Phe Ser
 65                  70                  75                  80

Glu Asp Gly Ala Leu Met Asp Gly Gly Met Asp Leu Asn Met Glu Gln
                 85                  90                  95

Gly Met Ala Glu His Leu Lys Asp Val Ile Leu Leu Thr Ala Ile Val
            100                 105                 110

Gln Val Leu Ser Cys Phe Ser Leu Tyr Val Trp Ser Phe Trp Leu Leu
        115                 120                 125

Ala Pro Gly Arg Ala Leu Tyr Leu Leu Trp Val Asn Val Leu Gly Pro
    130                 135                 140

Trp Phe Thr Ala Asp Ser Gly Thr Pro Ala Pro Glu His Asn Glu Lys
145                 150                 155                 160

Arg Gln Arg Arg Gln Glu Arg Arg Gln Met Lys Arg Leu 
                165                 170



<210> 1746
<211> 334
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (65)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1746
Met His Pro Gly Thr Arg Lys Arg Gly Arg Pro Pro Lys Tyr Asn Ala
  1               5                  10                  15

Val Leu Gly Phe Gly Ala Leu Thr Pro Thr Ser Pro Gln Ser Ser His
             20                  25                  30

Pro Asp Ser Pro Glu Asn Glu Lys Thr Xaa Thr Thr Phe Thr Phe Pro
         35                  40                  45

Ala Pro Val Gln Pro Val Ser Leu Pro Ser Pro Xaa Ser Thr Asp Gly
     50                  55                  60

Xaa Ile His Glu Xaa Phe Cys Ser Val Cys Arg Lys Ser Gly Gln Leu
 65                  70                  75                  80

Leu Met Cys Asp Thr Cys Ser Arg Val Tyr His Leu Asp Cys Leu Asp
                 85                  90                  95

Pro Pro Leu Lys Thr Ile Pro Lys Gly Met Trp Ile Cys Pro Arg Cys
            100                 105                 110

Gln Asp Gln Met Leu Lys Lys Glu Glu Ala Ile Pro Trp Pro Gly Thr
        115                 120                 125

Leu Ala Ile Val His Ser Tyr Ile Ala Tyr Lys Ala Ala Lys Glu Glu
    130                 135                 140

Glu Lys Gln Lys Leu Leu Lys Trp Ser Ser Asp Leu Lys Gln Glu Arg
145                 150                 155                 160

Glu Gln Leu Glu Gln Lys Val Lys Gln Leu Ser Asn Ser Ile Ser Lys
                165                 170                 175

Cys Met Glu Met Lys Asn Thr Ile Leu Ala Arg Gln Lys Glu Met His
            180                 185                 190

Ser Ser Leu Glu Lys Val Lys Gln Leu Ile Arg Leu Ile His Gly Ile
        195                 200                 205

Asp Leu Ser Lys Pro Val Asp Ser Glu Ala Thr Val Gly Pro Ser Pro
    210                 215                 220

Met Ala Arg Thr Ala Pro Pro Leu Pro Met Pro Pro Pro Pro Arg Arg
225                 230                 235                 240

Pro Leu Pro Pro Pro Pro Arg Ala Ala Gln Arg Thr Val Thr Arg Gly
                245                 250                 255

Lys Arg Leu Asn Asn Arg Ala Pro Leu Gly Glu Ala Thr Gly Ser Arg
            260                 265                 270

Arg Gln Gly Glu Gln Asn Thr Glu Asp Ser Arg Lys Ala Lys Pro Asp
        275                 280                 285

Phe Trp Lys Val Gln Asn Ser Phe Gly Ser Leu Val Pro Glu Arg Glu
    290                 295                 300

Lys Met Leu Val Pro Gly Gly Thr Arg Val Cys Gln Leu Ile Leu Leu
305                 310                 315                 320

Ile Leu Cys Val His Ala Lys Ile Gly Pro Cys Tyr Met Lys 
                325                 330



<210> 1747
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1747
Met Ala Trp Ser Leu Phe Pro Pro Leu Pro Arg Pro Leu Val Ser Met
  1               5                  10                  15

Ser Pro Pro His Ala Leu Phe Gln Ile Met Leu Gly Ile Phe Phe Asn
             20                  25                  30

Val His Ser Ala Val Leu Ile Glu Asp Val Pro Phe Thr Glu Lys Asp
         35                  40                  45

Phe Glu Asn Gly Pro Gln Asn Ile Tyr Asn Leu Tyr Glu Gln Val Ser
     50                  55                  60

Tyr Asn Cys Phe Ile Ala Ala Gly Leu Tyr Leu Leu Leu Gly Gly Phe
 65                  70                  75                  80

Ser Phe Cys Gln Val Arg Leu Asn Lys Arg Lys Gly Ile His Gly Cys
                 85                  90                  95

Ala Arg Gly Pro Gly Gly Val Phe Pro Ala Pro Ala Pro Pro Leu Phe
            100                 105                 110

Xaa Arg Xaa Pro Trp His Arg Val His Pro Gly Ser Xaa Ser His Pro
        115                 120                 125

Leu Pro Gly Xaa Phe Val Gly Ile 
    130                 135



<210> 1748
<211> 139
<212> PRT
<213> Homo sapiens

<400> 1748
Met Glu Glu Glu Ala Tyr Ser Lys Gly Phe Gln Glu Gly Leu Lys Lys
  1               5                  10                  15

Thr Lys Glu Leu Gln Asp Leu Lys Glu Glu Glu Glu Glu Gln Lys Ser
             20                  25                  30

Glu Ser Pro Glu Glu Pro Glu Glu Val Glu Glu Thr Glu Glu Glu Glu
         35                  40                  45

Lys Gly Pro Arg Ser Ser Lys Leu Glu Glu Leu Val His Phe Leu Gln
     50                  55                  60

Val Met Tyr Pro Lys Leu Cys Gln His Trp Gln Val Ile Trp Met Met
 65                  70                  75                  80

Ala Ala Val Met Leu Val Leu Thr Val Val Leu Gly Leu Tyr Asn Ser
                 85                  90                  95

Tyr Asn Ser Cys Ala Glu Gln Ala Asp Gly Pro Leu Gly Arg Ser Thr
            100                 105                 110

Cys Ser Ala Ala Pro Gly Thr Pro Gly Gly Ala Gln Asp Ser Ser Met
        115                 120                 125

Ser Ser Leu Gln Ser Ser Arg Lys Pro His Thr 
    130                 135



<210> 1749
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1749
Met Gln Lys Val Ile Lys Phe Thr Ser Glu Leu Leu Ala Phe Glu Pro
  1               5                  10                  15

Ala Ala Thr Ser Leu Ser Arg Pro Gly Leu Asn Ile Val Leu Ser Glu
             20                  25                  30

Val Leu Lys Met Leu Gln Ser Trp Ile Ser Gly Asn Val Ala Ala Pro
         35                  40                  45

Leu Leu Thr Thr Ser Ser Leu Ile Val Leu Lys Leu Ala Leu Gly Met
     50                  55                  60

Ala Ala Phe Ser Asn His Phe Gln Leu Glu Trp Val Leu Leu Lys Lys
 65                  70                  75                  80

Ser Asn Ile Ile Pro Ala Val Glu Lys Gly Ser Leu Arg Glu Lys Val
                 85                  90                  95

Leu Ala Lys Phe Cys Leu Cys Ala Xaa Val 
            100                 105



<210> 1750
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1750
Met Leu Glu Gly Val Ser Asn Glu Phe Asp His Phe Gly Ile Ser Leu
  1               5                  10                  15

Pro Leu Lys Ile Cys Leu His Leu Gly Trp Asp Glu Gly Leu Val Glu
             20                  25                  30

Gly Lys Val Val Arg Leu Gly Gln Gly Ile Gly Lys Ser Ile Cys Ser
         35                  40                  45

Ser Cys Gln Leu Phe Glu Glu Ala Pro Thr Gln Met Ser Thr Val Pro
     50                  55                  60

Ser Gly Leu Pro Leu Pro Ile Leu Met His Leu Cys Leu Leu Pro Val
 65                  70                  75                  80

Cys Met Ala His Leu Cys Pro Ala Ser Pro Cys Tyr Phe Gly Ala Thr
                 85                  90                  95

Pro Gly Ser Gly Lys Phe Cys Arg Leu Ile Thr Tyr Ser His Ser Ser
            100                 105                 110

Pro Gln Leu Ala Xaa Ser 
        115



<210> 1751
<211> 163
<212> PRT
<213> Homo sapiens

<400> 1751
Met Ala Gly Phe Tyr Gly Leu Tyr Thr Trp Leu Thr His Thr Met Phe
  1               5                  10                  15

Gly Ile Asn Ile Val Phe Ile Pro Ser Ala Leu Ala Ala Ile Leu Gly
             20                  25                  30

Ala Val Pro Phe Leu Gly Thr Tyr Trp Ala Ala Val Pro Ala Val Leu
         35                  40                  45

Asp Leu Trp Leu Thr Gln Gly Leu Gly Cys Lys Ala Ile Leu Leu Leu
     50                  55                  60

Ile Phe His Leu Leu Pro Thr Tyr Phe Val Asp Thr Ala Ile Tyr Ser
 65                  70                  75                  80

Asp Ile Ser Gly Gly Gly His Pro Tyr Leu Thr Gly Leu Ala Val Ala
                 85                  90                  95

Gly Gly Ala Tyr Tyr Leu Gly Leu Glu Gly Ala Ile Ile Gly Pro Ile
            100                 105                 110

Leu Leu Cys Ile Leu Val Val Ala Ser Asn Ile Tyr Ser Ala Met Leu
        115                 120                 125

Val Ser Pro Thr Asn Ser Val Pro Thr Pro Asn Gln Thr Pro Trp Pro
    130                 135                 140

Ala Gln Pro Gln Arg Thr Phe Arg Asp Ile Ser Glu Asp Leu Lys Ser
145                 150                 155                 160

Ser Val Gly 




<210> 1752
<211> 180
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (175)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1752
Met Ala Gly Gln Phe Arg Ser Tyr Val Trp Asp Pro Leu Leu Ile Leu
  1               5                  10                  15

Ser Gln Ile Val Leu Met Gln Thr Val Tyr Tyr Gly Ser Leu Gly Leu
             20                  25                  30

Trp Leu Ala Leu Val Asp Gly Leu Val Arg Ser Ser Pro Ser Leu Asp
         35                  40                  45

Gln Met Phe Asp Ala Glu Ile Leu Gly Phe Ser Thr Pro Pro Gly Arg
     50                  55                  60

Leu Ser Met Met Ser Phe Ile Leu Asn Ala Leu Thr Cys Ala Leu Gly
 65                  70                  75                  80

Leu Leu Tyr Phe Ile Arg Arg Gly Lys Gln Cys Leu Asp Phe Thr Val
                 85                  90                  95

Thr Val His Phe Phe His Leu Leu Gly Cys Trp Phe Tyr Ser Xaa Arg
            100                 105                 110

Phe Pro Ser Ala Leu Thr Trp Trp Leu Val Gln Ala Val Cys Ile Asp
        115                 120                 125

Ser Trp Leu Ala Ser Gly Ser Thr Cys Ala Cys Gly Arg Ser Ser Arg
    130                 135                 140

Arg Tyr Pro Leu Thr Xaa Ala Leu Asn Xaa Met Ser Arg Ile Ser Pro
145                 150                 155                 160

Leu Asp Xaa Leu Leu Thr Leu Gly Pro Leu Asn Thr Leu Gly Xaa Leu
                165                 170                 175

Xaa Pro Ser Asp 
            180



<210> 1753
<211> 124
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1753
Met Trp Asn Ser Ser Asp Ala Asn Phe Ser Cys Tyr His Glu Ser Val
  1               5                  10                  15

Leu Gly Tyr Arg Tyr Val Ala Val Ser Trp Gly Val Val Val Ala Val
             20                  25                  30

Thr Gly Thr Val Gly Asn Val Leu Thr Leu Leu Ala Leu Ala Ile Gln
         35                  40                  45

Pro Lys Leu Arg Thr Arg Phe Asn Leu Leu Ile Ala Asn Leu Thr Leu
     50                  55                  60

Ala Asp Leu Leu Tyr Cys Thr Leu Leu Gln Pro Phe Ser Val Asp Thr
 65                  70                  75                  80

Tyr Leu His Leu Xaa Trp Arg Thr Gly Ala Thr Phe Cys Arg Val Phe
                 85                  90                  95

Xaa Leu Leu Leu Phe Ala Ser Asn Ser Val Ser Ile Leu Thr Leu Cys
            100                 105                 110

Ser Ser His Trp Asp Ala Asn Ser Ser Leu Pro Asn 
        115                 120



<210> 1754
<211> 285
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (191)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1754
Met Pro Gly Leu Asp Val Tyr Phe Ala Ala Asp Val Cys Tyr Ala Glu
  1               5                  10                  15

Lys Val Ala Gln Glu Lys Gly Phe Leu Tyr Arg Leu Thr Ser Arg Tyr
             20                  25                  30

Arg His Tyr Ala Ala Phe Glu Arg Ala Thr Phe Glu Gln Gly Lys Ser
         35                  40                  45

Thr Lys Leu Met Met Leu Thr Asp Lys Gln Ile Ala Asp Phe Gln Lys
     50                  55                  60

His Tyr Gln Thr Glu Pro Glu Arg Phe Gln Ile Leu Pro Pro Gly Ile
 65                  70                  75                  80

Tyr Pro Asp Arg Lys Tyr Ser Glu Gln Ile Pro Asn Ser Arg Glu Ile
                 85                  90                  95

Tyr Arg Gln Lys Asn Gly Ile Lys Glu Xaa Gln Asn Leu Leu Leu Gln
            100                 105                 110

Val Gly Ser Asp Phe Gly Arg Lys Gly Val Asp Arg Ser Ile Glu Ala
        115                 120                 125

Leu Ala Ser Leu Pro Glu Ser Leu Arg His Asn Thr Leu Leu Phe Val
    130                 135                 140

Val Gly Gln Asp Lys Pro Arg Lys Phe Glu Xaa Leu Ala Glu Lys Leu
145                 150                 155                 160

Gly Val Arg Ser Asn Val His Phe Phe Ser Gly Arg Asn Asp Val Ser
                165                 170                 175

Glu Leu Met Ala Ala Ala Asp Leu Leu Leu His Pro Ala Tyr Xaa Glu
            180                 185                 190

Ala Ala Gly Ile Val Leu Leu Glu Ala Ile Thr Ala Gly Leu Pro Val
        195                 200                 205

Leu Thr Thr Ala Val Cys Gly Tyr Ala His Tyr Ile Ala Asp Ala Asn
    210                 215                 220

Cys Gly Thr Val Ile Ala Glu Pro Phe Ser Xaa Glu Gln Leu Asn Glu
225                 230                 235                 240

Val Leu Arg Lys Ala Leu Thr Gln Ser Pro Leu Arg Met Ala Trp Ala
                245                 250                 255

Glu Asn Ala Arg His Tyr Ala Asp Thr Gln Asp Leu Tyr Ser Leu Pro
            260                 265                 270

Glu Lys Ala Ala Asp Ile Ile Thr Gly Gly Leu Asp Gly 
        275                 280                 285



<210> 1755
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1755
Met Leu Arg Val Val Leu Pro Gly Arg Val Gly Gly Gly Pro Pro Gly
  1               5                  10                  15

Thr Ala Leu Ser Ser Leu Ser Leu Pro His Ser Glu Ser Leu Gly Gly
             20                  25                  30

Leu His Gln Cys Arg Gln Gly Leu Gln Ser Pro Gly Pro Gly Leu Val
         35                  40                  45

Pro Leu Leu Arg Trp Ser Thr Leu Ala Ala Leu Gly Phe Gly Pro Ala
     50                  55                  60

Phe Cys Leu Pro Leu Gly Ser Val Ser Ser Arg Asp Gln Leu Leu Gly
 65                  70                  75                  80

Phe Ala Gly Gly Ala Ser Cys Gly Gly Ala Leu Pro Xaa Ala Leu Ser
                 85                  90                  95

Ser Xaa Gln Ser Cys Xaa Pro Ser Leu Leu 
            100                 105



<210> 1756
<211> 366
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1756
Met Ser Pro Gly Asp Pro Xaa Trp Leu Asp Val Ile Glu Arg Asp Leu
  1               5                  10                  15

His Arg Gln Phe Pro Phe His Glu Met Phe Val Ser Arg Gly Gly His
             20                  25                  30

Gly Gln Gln Asp Leu Phe Arg Val Leu Lys Ala Tyr Thr Leu Tyr Arg
         35                  40                  45

Pro Glu Glu Gly Tyr Cys Gln Ala Gln Ala Pro Ile Ala Ala Val Leu
     50                  55                  60

Leu Met His Met Pro Ala Glu Gln Ala Phe Trp Cys Leu Val Gln Ile
 65                  70                  75                  80

Cys Glu Lys Tyr Leu Pro Gly Tyr Tyr Ser Glu Lys Leu Glu Ala Ile
                 85                  90                  95

Gln Leu Asp Gly Glu Ile Leu Phe Ser Leu Leu Gln Lys Val Ser Pro
            100                 105                 110

Val Ala His Lys His Leu Ser Arg Gln Lys Ile Asp Pro Leu Leu Tyr
        115                 120                 125

Met Thr Glu Trp Phe Met Cys Ala Phe Ser Arg Thr Leu Pro Trp Ser
    130                 135                 140

Ser Val Leu Arg Val Trp Asp Met Phe Phe Cys Glu Gly Val Lys Ile
145                 150                 155                 160

Ile Phe Arg Val Gly Leu Val Leu Leu Lys His Ala Leu Gly Ser Pro
                165                 170                 175

Glu Lys Val Lys Ala Cys Gln Gly Gln Tyr Glu Thr Ile Glu Arg Leu
            180                 185                 190

Arg Ser Leu Ser Pro Lys Ile Met Gln Glu Ala Phe Leu Val Gln Glu
        195                 200                 205

Val Val Glu Leu Pro Val Thr Glu Arg Gln Ile Glu Arg Glu His Leu
    210                 215                 220

Ile Gln Leu Arg Arg Trp Gln Glu Thr Arg Gly Glu Leu Gln Cys Arg
225                 230                 235                 240

Ser Pro Pro Arg Leu His Gly Ala Lys Ala Ile Leu Asp Ala Glu Pro
                245                 250                 255

Gly Pro Arg Pro Ala Leu Gln Pro Ser Pro Ser Ile Arg Leu Pro Leu
            260                 265                 270

Asp Ala Pro Leu Pro Gly Ser Lys Ala Lys Pro Lys Pro Pro Lys Gln
        275                 280                 285

Ala Gln Lys Glu Gln Arg Lys Gln Met Lys Gly Arg Gly Gln Leu Glu
    290                 295                 300

Lys Pro Pro Ala Pro Asn Gln Ala Met Val Val Ala Ala Ala Gly Asp
305                 310                 315                 320

Ala Cys Pro Pro Gln His Val Pro Pro Lys Asp Ser Ala Pro Lys Asp
                325                 330                 335

Ser Ala Pro Gln Asp Leu Ala Pro Gln Val Ser Ala His His Arg Ser
            340                 345                 350

Gln Glu Ser Leu Thr Ser Gln Glu Ser Glu Asp Thr Tyr Leu 
        355                 360                 365



<210> 1757
<211> 199
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1757
Met Gln Lys Glu Met Lys Met Ile Lys Asp Glu Asp Val His Phe Asp
  1               5                  10                  15

Leu Ala Val Lys Lys Thr Pro Ser Phe Pro His Cys Leu Gln Pro Val
             20                  25                  30

Ala Ser Arg Gly Lys Ala Pro Gln Arg His Pro Phe Pro Glu Ala Leu
         35                  40                  45

Arg Gly Pro Phe Ser Gln Phe Arg Tyr Glu Pro Pro Pro Gly Asp Leu
     50                  55                  60

Asp Gly Phe Pro Gly Val Phe Glu Gly Ala Xaa Ser Arg Lys Arg Lys
 65                  70                  75                  80

Ser Met Pro Thr Lys Met Pro Tyr Asn His Pro Ala Glu Glu Val Thr
                 85                  90                  95

Leu Ala Leu His Ser Glu Glu Asn Lys Asn His Gly Leu Pro Asn Leu
            100                 105                 110

Pro Leu Leu Phe Pro Gln Pro Pro Arg Pro Lys Tyr Asp Ser Gln Met
        115                 120                 125

Ile Asp Leu Cys Lys Trp Ala Ser Asn Ser Thr Ala Ala Trp Glu His
    130                 135                 140

Phe Gly Gly Lys Pro Val Lys Gln Glu Pro Ile Lys Pro Ser Ala Val
145                 150                 155                 160

Trp Pro Gln Pro Thr Pro Xaa Pro Phe Leu Pro Thr Pro Xaa Pro Tyr
                165                 170                 175

Xaa Pro Lys Phe His Xaa Gly Phe Met Phe Pro Leu Xaa Cys Gly Leu
            180                 185                 190

Val Leu Gly Leu Ser Leu Ser 
        195



<210> 1758
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1758
Met Lys Leu Tyr His Ser Trp Leu Leu Val Gly Ser Arg Thr Glu Val
  1               5                  10                  15

Thr Gln Val Asn Thr Thr Asn Cys Gly Arg Leu Gln Ser Cys Ser Glu
             20                  25                  30

Cys Ile Leu Ala Gln Asp Pro Val Cys Ala Trp Ser Phe Arg Leu Asp
         35                  40                  45

Glu Cys Val Ala His Ala Gly Glu His Arg Gly Leu Val Gln Asp Ile
     50                  55                  60

Glu Ser Ala Asp Val Ser Ser Leu Cys Pro Lys Glu Pro Gly Glu Arg
 65                  70                  75                  80

Pro Val Val Phe Glu Val Pro Val Ala Thr Ala Ala His Val Val Leu
                 85                  90                  95

Pro Cys Ser Pro Ser Ser Ala Xaa Ala Xaa Cys Val Trp His Gln Pro
            100                 105                 110

Ser Gly Val Xaa Ala Xaa Xaa Pro Arg Arg Asp Gly Leu Glu Val Val
        115                 120                 125

Val Xaa Pro Gly Ala Met Gly Ala Tyr Ala Cys Glu Cys Gln Glu Gly
    130                 135                 140

Gly Ala Ala His Val Val Ala Ala Tyr Ser Leu Val Trp Gly Ser Gln
145                 150                 155                 160

Arg Asp Ala Pro Ser Arg Ala 
                165



<210> 1759
<211> 174
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1759
Met Ala Pro Leu Pro Gly Ala Glu Leu Val Arg Arg Pro Leu Gln Leu
  1               5                  10                  15

Tyr Arg Tyr Leu Leu Arg Cys Cys Gln Gln Leu Pro Thr Lys Gly Ile
             20                  25                  30

Gln Gln His Tyr Lys His Ala Val Arg Gln Ser Phe Arg Val His Ser
         35                  40                  45

Asp Glu Asp Asn Pro Glu Arg Ile Gln Gln Ile Ile Lys Arg Ala Ile
     50                  55                  60

Glu Asp Ala Asp Trp Ile Met Asn Lys Tyr Lys Lys Gln Thr Glu Ser
 65                  70                  75                  80

Ser Glu Gly Glu Pro Ser Trp Pro Leu Glu Val Glu Arg Pro Leu Phe
                 85                  90                  95

Trp Ser Ser Ala Ala Ala Ala Gly Leu Glu Asp Pro Leu Ala Leu Leu
            100                 105                 110

Ala Glu Thr Arg Glu Ser Xaa Gly Glu Ala Asp Leu Ala Pro Glu Ala
        115                 120                 125

Pro Leu Ala Ala Ala Met Leu Leu Ser Ile Leu Tyr Val Cys Thr Ser
    130                 135                 140

Ser His Phe Thr Asp Val Lys Phe Gly Glu Asn Cys Lys Leu Phe Phe
145                 150                 155                 160

Cys Phe Phe Leu Cys Val Phe Tyr Trp Val Cys Phe Leu Phe 
                165                 170



<210> 1760
<211> 141
<212> PRT
<213> Homo sapiens

<400> 1760
Met Asp Thr Ala Tyr Pro Arg Glu Asp Thr Arg Ala Pro Thr Pro Ser
  1               5                  10                  15

Lys Ala Gly Ala His Thr Ala Leu Thr Leu Gly Ala Pro His Pro Pro
             20                  25                  30

Pro Arg Asp His Leu Ile Trp Ser Val Phe Ser Thr Leu Tyr Leu Asn
         35                  40                  45

Leu Cys Cys Leu Gly Phe Leu Ala Leu Ala Tyr Ser Ile Lys Ala Arg
     50                  55                  60

Asp Gln Lys Val Val Gly Asp Leu Glu Ala Ala Arg Arg Phe Gly Ser
 65                  70                  75                  80

Lys Ala Lys Cys Tyr Asn Ile Leu Ala Ala Met Trp Thr Leu Val Pro
                 85                  90                  95

Pro Leu Leu Leu Leu Gly Leu Val Val Thr Gly Ala Leu His Cys Ala
            100                 105                 110

Arg Leu Pro Arg Thr Leu Pro Pro Ser Ser Ala Pro Ser Leu Met Thr
        115                 120                 125

Arg Thr Met Thr Asp Arg Leu Gly Pro Asp Leu Gly His 
    130                 135                 140



<210> 1761
<211> 162
<212> PRT
<213> Homo sapiens

<400> 1761
Met His Leu Leu Pro Leu Asp Ser Ser Ser Thr Leu Thr Cys Thr Val
  1               5                  10                  15

Pro Ser Ala Cys Thr Lys Pro Pro Ser Arg Trp Arg Pro Thr Val Asp
             20                  25                  30

Ile Phe Phe Val Val Thr Leu Leu Leu Thr Val Phe Gly Glu Asp Asp
         35                  40                  45

Gln Ser Gln Asp Val Leu Arg Leu His Gln Asp Ile Asn Asp Tyr Asn
     50                  55                  60

Arg Arg Phe Ser Gly Gln Pro Arg Ser Ile Met Glu Arg Ile Met Asp
 65                  70                  75                  80

Leu Pro Thr Leu Leu Arg His Ala Phe Arg Glu Met Phe Ser Val Gly
                 85                  90                  95

Gly Leu Phe Trp Met Phe Arg Ile Arg Ile Ile Leu Cys Leu Met Gly
            100                 105                 110

Ala Phe Phe Tyr Leu Ile Ser Pro Leu Asp Phe Val Pro Glu Ala Leu
        115                 120                 125

Phe Gly Ile Leu Gly Phe Leu Asp Asp Phe Phe Val Ile Phe Leu Leu
    130                 135                 140

Leu Ile Tyr Ile Ser Ile Met Tyr Arg Glu Val Ile Thr Gln Arg Leu
145                 150                 155                 160

Thr Arg 




<210> 1762
<211> 246
<212> PRT
<213> Homo sapiens

<400> 1762
Met Ala Gln His Gly Ala Met Gly Ala Phe Arg Ala Leu Cys Gly Leu
  1               5                  10                  15

Ala Leu Leu Cys Ala Leu Ser Leu Gly Gln Arg Pro Thr Gly Gly Pro
             20                  25                  30

Gly Cys Gly Pro Gly Arg Leu Leu Leu Gly Thr Gly Thr Asp Ala Arg
         35                  40                  45

Cys Cys Arg Val His Thr Thr Arg Cys Cys Arg Asp Tyr Pro Ala Gln
     50                  55                  60

Leu Leu Gly Gly Trp Pro Val Ser Cys Pro Gly Glu Glu Cys Cys Ser
 65                  70                  75                  80

Glu Trp Asp Cys Met Cys Val Gln Pro Glu Phe His Cys Gly Asp Pro
                 85                  90                  95

Cys Cys Thr Thr Cys Arg His His Pro Cys Pro Pro Gly Gln Gly Val
            100                 105                 110

Gln Ser Gln Gly Lys Phe Ser Phe Gly Phe Gln Cys Ile Asp Cys Ala
        115                 120                 125

Ser Gly Thr Phe Ser Gly Gly His Glu Gly His Cys Lys Pro Trp Thr
    130                 135                 140

Asp Cys Thr Gln Phe Gly Phe Leu Thr Val Phe Pro Gly Asn Lys Thr
145                 150                 155                 160

His Asn Ala Val Cys Val Pro Gly Ser Pro Pro Ala Glu Pro Leu Gly
                165                 170                 175

Trp Leu Thr Val Val Leu Leu Ala Val Ala Ala Cys Val Leu Leu Leu
            180                 185                 190

Thr Ser Ala Gln Leu Gly Leu His Ile Trp Gln Leu Arg Lys Thr Gln
        195                 200                 205

Leu Leu Leu Glu Val Pro Pro Ser Thr Glu Asp Ala Arg Ser Cys Gln
    210                 215                 220

Phe Pro Glu Glu Glu Arg Gly Glu Arg Ser Ala Glu Glu Lys Gly Arg
225                 230                 235                 240

Leu Gly Asp Leu Trp Val 
                245



<210> 1763
<211> 152
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (46)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1763
Met Ser Arg Arg Arg Phe Asp Cys Arg Ser Ile Ser Xaa Leu Leu Thr
  1               5                  10                  15

Thr Thr Pro Gln Ile Pro Ile Lys Met Glu Asn Phe Asn Asn Phe Tyr
             20                  25                  30

Ile Leu Thr Ser Lys Glu Leu Gly Arg Gly Lys Phe Ala Xaa Val Arg
         35                  40                  45

Gln Xaa Ile Ser Lys Ser Thr Gly Gln Glu Tyr Ala Ala Lys Phe Leu
     50                  55                  60

Lys Lys Arg Arg Arg Gly Gln Asp Cys Arg Ala Glu Ile Leu His Glu
 65                  70                  75                  80

Ile Ala Val Leu Glu Leu Ala Lys Ser Cys Pro Arg Val Ile Asn Leu
                 85                  90                  95

His Glu Val Tyr Glu Asn Thr Ser Glu Ile Ile Leu Ile Leu Glu Tyr
            100                 105                 110

Ala Ala Gly Gly Glu Ile Phe Ser Leu Cys Leu Pro Glu Leu Ala Glu
        115                 120                 125

Met Val Ser Glu Asn Asp Val Ile Arg Leu Ile Lys Gln Ile Leu Glu
    130                 135                 140

Gly Val Tyr Tyr Leu His Pro Glu 
145                 150



<210> 1764
<211> 614
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1764
Met Met Asn Thr Ile Ile Phe His Thr Lys Met Val Asp Ser Leu Val
  1               5                  10                  15

Glu Met Leu Val Glu Thr Ser Asp Leu Ser Ile Phe Cys Phe Tyr Ser
             20                  25                  30

Arg Ala Phe Glu Lys Met Phe Gln Gln Cys Leu Glu Leu Pro Ser Gln
         35                  40                  45

Ser Arg Tyr Ser Ile Ala Phe Pro Leu Leu Cys Thr His Phe Met Ser
     50                  55                  60

Cys Thr His Glu Leu Cys Pro Glu Glu Arg His His Ile Gly Asp Arg
 65                  70                  75                  80

Ser Leu Ser Leu Cys Asn Met Phe Leu Asp Glu Met Ala Lys Gln Ala
                 85                  90                  95

Arg Asn Leu Ile Thr Asp Ile Cys Xaa Glu Gln Cys Thr Leu Ser Asp
            100                 105                 110

Gln Leu Leu Pro Lys His Cys Ala Lys Thr Ile Ser Gln Ala Val Asn
        115                 120                 125

Lys Lys Ser Lys Lys Gln Thr Gly Lys Lys Gly Glu Pro Glu Arg Glu
    130                 135                 140

Lys Pro Gly Val Glu Ser Met Arg Lys Asn Arg Leu Val Val Thr Asn
145                 150                 155                 160

Leu Asp Lys Leu His Thr Ala Leu Ser Glu Leu Cys Phe Ser Ile Asn
                165                 170                 175

Tyr Val Pro Asn Met Val Val Trp Glu His Thr Phe Thr Pro Arg Glu
            180                 185                 190

Tyr Leu Thr Ser His Leu Glu Ile Arg Phe Thr Lys Ser Ile Val Gly
        195                 200                 205

Met Thr Met Tyr Asn Gln Ala Thr Gln Glu Ile Ala Lys Pro Ser Glu
    210                 215                 220

Leu Leu Thr Ser Val Arg Ala Tyr Met Thr Val Leu Gln Ser Ile Glu
225                 230                 235                 240

Asn Tyr Val Gln Ile Asp Ile Thr Arg Val Phe Asn Asn Val Leu Leu
                245                 250                 255

Gln Gln Thr Gln His Leu Asp Ser His Gly Glu Pro Thr Ile Thr Ser
            260                 265                 270

Leu Tyr Thr Asn Trp Tyr Leu Glu Thr Leu Leu Arg Gln Val Ser Asn
        275                 280                 285

Gly His Ile Ala Tyr Phe Pro Ala Met Lys Ala Phe Val Asn Leu Pro
    290                 295                 300

Thr Glu Asn Glu Leu Thr Phe Asn Ala Glu Glu Tyr Ser Asp Ile Ser
305                 310                 315                 320

Glu Met Arg Ser Leu Ser Glu Leu Leu Gly Pro Tyr Gly Met Lys Phe
                325                 330                 335

Leu Ser Glu Ser Leu Met Trp His Ile Ser Ser Gln Val Ala Glu Leu
            340                 345                 350

Lys Lys Leu Val Val Glu Asn Val Asp Val Leu Thr Gln Met Arg Thr
        355                 360                 365

Ser Phe Asp Lys Pro Asp Gln Met Ala Ala Leu Phe Lys Arg Leu Ser
    370                 375                 380

Ser Val Asp Ser Val Leu Lys Arg Met Thr Ile Ile Gly Val Ile Leu
385                 390                 395                 400

Ser Phe Arg Ser Leu Ala Gln Glu Ala Leu Arg Asp Val Leu Ser Tyr
                405                 410                 415

His Ile Pro Phe Leu Val Ser Ser Ile Glu Asp Phe Lys Asp His Ile
            420                 425                 430

Pro Arg Glu Thr Asp Met Lys Val Ala Met Asn Val Tyr Glu Leu Ser
        435                 440                 445

Ser Ala Ala Gly Leu Pro Cys Glu Ile Asp Pro Ala Leu Val Val Ala
    450                 455                 460

Leu Ser Ser Gln Lys Ser Glu Asn Ile Ser Pro Glu Glu Glu Tyr Lys
465                 470                 475                 480

Ile Ala Cys Leu Leu Met Val Phe Val Ala Val Ser Leu Pro Thr Leu
                485                 490                 495

Ala Ser Asn Val Met Ser Gln Tyr Ser Pro Ala Ile Glu Gly His Cys
            500                 505                 510

Asn Asn Ile His Cys Leu Ala Lys Ala Ile Asn Gln Ile Ala Ala Ala
        515                 520                 525

Leu Phe Thr Ile His Lys Gly Ser Ile Glu Asp Arg Leu Lys Glu Phe
    530                 535                 540

Leu Ala Leu Ala Ser Ser Ser Leu Leu Lys Ile Gly Gln Glu Thr Asp
545                 550                 555                 560

Lys Thr Thr Thr Arg Asn Arg Glu Ser Val Tyr Leu Leu Leu Asp Met
                565                 570                 575

Ile Val Gln Glu Ser Pro Phe Leu Thr Met Asp Leu Leu Glu Ser Cys
            580                 585                 590

Phe Pro Tyr Val Leu Leu Arg Asn Ala Tyr His Ala Val Tyr Lys Gln
        595                 600                 605

Ser Val Thr Ser Ser Ala 
    610



<210> 1765
<211> 323
<212> PRT
<213> Homo sapiens

<400> 1765
Met Gly Asn Ser Ala Ser Arg Asn Asp Phe Glu Trp Val Tyr Thr Asp
  1               5                  10                  15

Gln Pro His Thr Gln Arg Arg Ala Arg Pro Pro Ala Lys Tyr Pro Ala
             20                  25                  30

Ile Lys Ala Leu Met Arg Pro Asp Pro Arg Leu Lys Trp Ala Val Leu
         35                  40                  45

Val Leu Val Leu Val Gln Met Leu Ala Cys Trp Leu Val Arg Gly Leu
     50                  55                  60

Ala Trp Arg Trp Leu Leu Phe Trp Ala Tyr Ala Phe Gly Gly Cys Val
 65                  70                  75                  80

Asn His Ser Leu Thr Leu Ala Ile His Asp Ile Ser His Asn Ala Ala
                 85                  90                  95

Phe Gly Thr Gly Arg Ala Ala Arg Asn Arg Trp Leu Ala Val Phe Ala
            100                 105                 110

Asn Leu Pro Val Gly Val Pro Tyr Ala Ala Ser Phe Lys Lys Tyr His
        115                 120                 125

Val Asp His His Arg Tyr Leu Gly Gly Asp Gly Leu Asp Val Asp Val
    130                 135                 140

Pro Thr Arg Leu Glu Gly Trp Phe Phe Cys Thr Pro Ala Arg Lys Leu
145                 150                 155                 160

Leu Trp Leu Val Leu Gln Pro Phe Phe Tyr Ser Leu Arg Pro Leu Cys
                165                 170                 175

Val His Pro Lys Ala Val Thr Arg Met Glu Val Leu Asn Thr Leu Val
            180                 185                 190

Gln Leu Ala Ala Asp Leu Ala Ile Phe Ala Leu Trp Gly Leu Lys Pro
        195                 200                 205

Val Val Tyr Leu Leu Ala Ser Ser Phe Leu Gly Leu Gly Leu His Pro
    210                 215                 220

Ile Ser Gly His Phe Val Ala Glu His Tyr Met Phe Leu Lys Gly His
225                 230                 235                 240

Glu Thr Tyr Ser Tyr Tyr Gly Pro Leu Asn Trp Ile Thr Phe Asn Val
                245                 250                 255

Gly Tyr His Val Glu His His Asp Phe Pro Ser Ile Pro Gly Tyr Asn
            260                 265                 270

Leu Pro Leu Val Arg Lys Ile Ala Pro Glu Tyr Tyr Asp His Leu Pro
        275                 280                 285

Gln His His Ser Trp Val Lys Val Leu Trp Asp Phe Val Phe Glu Asp
    290                 295                 300

Ser Leu Gly Pro Tyr Ala Arg Val Lys Arg Val Tyr Arg Leu Ala Lys
305                 310                 315                 320

Asp Gly Leu 




<210> 1766
<211> 106
<212> PRT
<213> Homo sapiens

<400> 1766
Met Thr Ser Gly Gln Met Trp Asn His Ile Arg Gly Pro Pro Tyr Ala
  1               5                  10                  15

His Lys Asn Pro His Thr Gly His Val Asn Tyr Ile His Gly Ser Ser
             20                  25                  30

Gln Ala Gln Phe Val Ala Glu Thr His Ile Val Leu Leu Phe Asn Gly
         35                  40                  45

Gly Val Thr Leu Gly Met Val Leu Leu Cys Glu Ala Ala Thr Ser Asp
     50                  55                  60

Met Asp Ile Gly Lys Arg Lys Ile Met Cys Val Ala Gly Ile Gly Leu
 65                  70                  75                  80

Val Val Leu Phe Phe Ser Trp Met Leu Ser Ile Phe Arg Ser Lys Tyr
                 85                  90                  95

His Gly Tyr Pro Tyr Ser Phe Leu Met Ser 
            100                 105



<210> 1767
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1767
Met Leu Phe His Ser Phe Asn Leu Arg Trp Asn Trp Leu Glu Arg Arg
  1               5                  10                  15

Asn Arg Thr Leu Phe Lys Thr Arg Glu Met Val Tyr Pro Pro Leu Ala
             20                  25                  30

Glu Asn Thr Gly Lys Thr Leu Pro Leu Val Leu Asp Gly Arg Thr Ser
         35                  40                  45

Phe Phe Phe Phe Leu Ser Phe Leu Phe Val Cys Leu Phe Gly Thr Lys
     50                  55                  60

Ser His Ser Val Ala Gln Ala Gly Gly Cys Ser Glu Leu Arg Ser His
 65                  70                  75                  80

His Cys Asn Ser Ser Leu Ser Asn Lys Ala Arg Leu His Leu Leu Lys
                 85                  90                  95

Lys Lys Lys Lys Asn Ser Lys Gly Gly Pro Val Xaa Gln Leu Ala Xaa
            100                 105                 110

Lys 




<210> 1768
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1768
Met Leu Ser Ala Arg Asp Arg Arg Asp Arg His Pro Glu Glu Gly Val
  1               5                  10                  15

Val Ala Glu Leu Gln Gly Phe Ala Val Asp Lys Ala Phe Leu Thr Ser
             20                  25                  30

His Lys Gly Ile Leu Leu Glu Thr Glu Leu Ala Leu Thr Leu Ile Ile
         35                  40                  45

Phe Ile Cys Phe Thr Ala Ser Ile Ser Ala Tyr Met Ala Ala Ala Leu
     50                  55                  60

Leu Glu Phe Phe Ile Thr Leu Ala Phe Leu Phe Leu Tyr Ala Thr Gln
 65                  70                  75                  80

Tyr Tyr Gln Arg Phe Asp Arg Ile Asn Trp Xaa Cys Leu Asp Phe Leu
                 85                  90                  95

Arg Cys Val Ser Ala Ile Ile Ile Phe Leu Val Xaa Ser Phe Xaa Ser
            100                 105                 110

Cys Asp Leu Pro Gly Trp Ser Cys His Cys Cys 
        115                 120



<210> 1769
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1769
Met Asn Asp Gln Gly Glu Ile Tyr Ser Thr Leu Arg Phe Leu Gln Ser
  1               5                  10                  15

Pro Ser Glu Ser Gln Asn Arg Leu Arg Pro Asp Asp Thr Gln Arg Pro
             20                  25                  30

Gly Lys Thr Asp Asp Lys Glu Phe Ser Val Pro Trp His Leu Ile Ala
         35                  40                  45

Val Thr Leu Gly Ile Leu Cys Leu Leu Leu Leu Met Ile Val Thr Val
     50                  55                  60

Leu Val Thr Asn Ile Phe Gln Cys Ile Gln Glu Lys His Gln Arg Gln
 65                  70                  75                  80

Glu Ile Leu Arg Asn Cys Ser Glu Lys Tyr Ile Met Gln Asn Asp Asn
                 85                  90                  95

Tyr Leu Lys Glu Gln Ile Leu Thr Asn Lys Thr Leu Lys Tyr Asp Val
            100                 105                 110

Leu Lys Asn Ser Phe Gln Gln Lys Lys Glu Leu Asp Ser Arg Leu Ile
        115                 120                 125

Gln Lys Asn Arg Cys His Arg Glu Xaa Glu Ile Xaa Phe Lys Val Leu
    130                 135                 140

Gln Asn Thr Gly Asn Ser Leu Lys Thr Thr Gly Pro 
145                 150                 155



<210> 1770
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1770
Met Glu Val Leu Asp Lys Asn Leu Phe Phe Phe Phe Phe Leu Arg Trp
  1               5                  10                  15

Ser Leu Gly Leu Ser Pro Arg Leu Glu Cys Ser Gly Thr Ile Ser Ala
             20                  25                  30

His Cys Asn Leu His Leu Leu Gly Ser Ser Asp Ser Pro Ala Ser Ala
         35                  40                  45

Ser Arg Val Ala Gly Ile Ala Gly Ala Arg His Cys Ala Trp Leu Ile
     50                  55                  60

Phe Phe Phe Phe Cys Ile Phe Gly Arg Asp Gly Val Ser Pro Ser Leu
 65                  70                  75                  80

Ala Arg Leu Val Ser Glu Leu Leu Thr Leu Arg Ser Thr Pro Pro Arg
                 85                  90                  95

Pro Ser Lys Xaa Leu Gly Ile Lys Gly Leu Ser His Arg Ala Gln Xaa
            100                 105                 110

Ala Ile Ile Tyr Phe Leu Pro Phe Pro Phe Leu Arg Gly Tyr Xaa Xaa
        115                 120                 125

Gly Ser Trp 
    130



<210> 1771
<211> 112
<212> PRT
<213> Homo sapiens

<400> 1771
Met Arg Leu Glu Ala Thr Gln Leu Glu Gly Val Ala Arg Arg Met Thr
  1               5                  10                  15

Val Glu Thr Asp Tyr Cys Leu Leu Leu Ala Leu Pro Cys Gly Arg Asp
             20                  25                  30

Gln Glu Asp Val Val Ser Gln Thr Glu Ser Leu Lys Ala Ala Phe Ile
         35                  40                  45

Thr Tyr Leu Gln Ala Lys Gln Ala Ala Gly Ile Ile Asn Val Pro Asn
     50                  55                  60

Pro Gly Ser Asn Gln Pro Ala Tyr Val Leu Gln Ile Phe Pro Pro Cys
 65                  70                  75                  80

Glu Phe Ser Glu Ser His Leu Ser Arg Leu Ala Pro Asp Leu Leu Ala
                 85                  90                  95

Ser Ile Ser Asn Ile Ser Pro His Leu Met Ile Val Ile Ala Ser Val
            100                 105                 110






<210> 1772
<211> 125
<212> PRT
<213> Homo sapiens

<400> 1772
Met Lys Gly Asp Pro Val Asn Tyr Ile Leu Gln Val Leu Val Gly Arg
  1               5                  10                  15

Glu Ser Glu Tyr Lys Gln Val Tyr Lys Gly Glu Glu Ala Thr Phe Gln
             20                  25                  30

Ile Ser Gly Leu Gln Thr Asn Thr Asp Tyr Arg Phe Arg Val Cys Ala
         35                  40                  45

Cys Arg Arg Cys Leu Asp Thr Ser Gln Glu Leu Ser Gly Ala Phe Ser
     50                  55                  60

Pro Ser Ala Ala Phe Val Leu Gln Arg Ser Glu Val Met Leu Thr Gly
 65                  70                  75                  80

Asp Met Gly Ser Leu Asp Asp Pro Lys Met Lys Ser Met Met Pro Thr
                 85                  90                  95

Asp Glu Gln Phe Ala Ala Ile Ile Val Leu Gly Phe Ala Thr Leu Ser
            100                 105                 110

Ile Leu Phe Ala Phe Ile Leu Gln Tyr Phe Leu Met Lys 
        115                 120                 125



<210> 1773
<211> 110
<212> PRT
<213> Homo sapiens

<400> 1773
Met Ala Ala Val Val Ala Lys Arg Glu Gly Pro Pro Phe Ile Ser Glu
  1               5                  10                  15

Ala Ala Val Arg Gly Asn Ala Ala Val Leu Asp Tyr Cys Arg Thr Ser
             20                  25                  30

Val Ser Ala Leu Ser Gly Ala Thr Ala Gly Ile Leu Gly Leu Thr Gly
         35                  40                  45

Leu Tyr Gly Phe Ile Phe Tyr Leu Leu Ala Ser Val Leu Leu Ser Leu
     50                  55                  60

Leu Leu Ile Leu Lys Ala Gly Arg Arg Trp Asn Lys Tyr Phe Lys Ser
 65                  70                  75                  80

Arg Arg Pro Leu Phe Thr Gly Gly Leu Ile Gly Gly Leu Phe Thr Tyr
                 85                  90                  95

Val Leu Phe Trp Thr Phe Leu Tyr Gly Met Val His Val Tyr 
            100                 105                 110



<210> 1774
<211> 268
<212> PRT
<213> Homo sapiens

<400> 1774
Met Ile Phe Arg Gly Thr Gly Ala Leu Ile Phe Val Ile Asp Ser Gln
  1               5                  10                  15

Asp Asp Tyr Met Glu Ala Leu Ala Arg Leu His Leu Thr Val Thr Arg
             20                  25                  30

Ala Tyr Lys Val Asn Thr Asp Ile Asn Phe Glu Val Phe Ile His Lys
         35                  40                  45

Val Asp Gly Leu Ser Asp Asp His Lys Ile Glu Thr Gln Arg Asp Ile
     50                  55                  60

His Gln Arg Ala Asn Asp Asp Leu Ala Asp Ala Gly Leu Glu Lys Ile
 65                  70                  75                  80

His Leu Ser Phe Tyr Leu Thr Ser Ile Tyr Asp His Ser Ile Phe Glu
                 85                  90                  95

Ala Phe Ser Lys Val Val Gln Lys Leu Ile Pro Gln Leu Pro Thr Leu
            100                 105                 110

Glu Asn Leu Leu Asn Ile Phe Ile Ser Asn Ser Gly Ile Glu Lys Ala
        115                 120                 125

Phe Leu Phe Asp Val Val Ser Lys Ile Tyr Ile Ala Thr Asp Ser Thr
    130                 135                 140

Pro Val Asp Met Gln Thr Tyr Glu Leu Cys Cys Asp Met Ile Asp Val
145                 150                 155                 160

Val Ile Asp Ile Ser Cys Ile Tyr Gly Leu Lys Glu Asp Gly Ala Gly
                165                 170                 175

Thr Pro Tyr Asp Lys Glu Ser Thr Ala Ile Ile Lys Leu Asn Asn Thr
            180                 185                 190

Thr Val Leu Tyr Leu Lys Glu Val Thr Lys Phe Leu Ala Leu Val Cys
        195                 200                 205

Phe Val Arg Glu Glu Ser Phe Glu Arg Lys Gly Leu Ile Asp Tyr Asn
    210                 215                 220

Phe His Cys Phe Arg Lys Ala Ile His Glu Val Phe Glu Val Arg Met
225                 230                 235                 240

Lys Val Val Lys Ser Arg Lys Val Gln Asn Arg Leu Gln Lys Lys Lys
                245                 250                 255

Arg Ala Thr Pro Asn Gly Thr Pro Arg Val Leu Leu 
            260                 265



<210> 1775
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (147)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1775
Met Ala Val Glu Cys Ala Glu Ile Arg Arg His His Arg Val Gly Ile
  1               5                  10                  15

Lys Asp Ile Ala Gly Ile His Leu Pro Thr Asn Val Lys Phe Gln Ser
             20                  25                  30

Pro Ala Tyr Ser Ser Val Asp Thr Glu Glu Thr Ile Glu Pro Tyr Thr
         35                  40                  45

Thr Glu Lys Met Ser Arg Val Pro Gly Gly Tyr Leu Ala Leu Thr Glu
     50                  55                  60

Cys Phe Glu Ile Met Xaa Val Asp Phe Asn Asn Leu Gln Glu Leu Lys
 65                  70                  75                  80

Ser Leu Ala Thr Lys Lys Pro Gly Lys Ile Gly Ile Pro Val Ile Lys
                 85                  90                  95

Glu Gly Ile Leu Asp Ala Val Val Val Trp Phe Val Leu Gln Leu Asp
            100                 105                 110

Asp Glu His Ser Leu Ser Thr Ser Pro Asn Glu Glu Thr Cys Trp Glu
        115                 120                 125

Gln Ala Val Tyr Pro Val His Asp Leu Ala Asp Tyr Arg Ile Lys Arg
    130                 135                 140

Gly Asp Xaa 
145



<210> 1776
<211> 259
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1776
Met Ala Ala Ser Arg Leu Glu Leu Asn Leu Val Arg Leu Leu Xaa Arg
  1               5                  10                  15

Cys Glu Ala Met Ala Ala Glu Lys Arg Asp Pro Asp Glu Trp Arg Leu
             20                  25                  30

Glu Lys Tyr Val Gly Ala Leu Glu Asp Met Leu Gln Ala Leu Lys Val
         35                  40                  45

His Ala Ser Lys Pro Ala Ser Glu Val Ile Asn Glu Tyr Ser Trp Lys
     50                  55                  60

Val Asp Phe Leu Lys Gly Met Leu Gln Ala Glu Lys Leu Thr Ser Ser
 65                  70                  75                  80

Ser Glu Lys Ala Leu Ala Asn Gln Phe Leu Ala Pro Gly Arg Val Pro
                 85                  90                  95

Thr Thr Ala Arg Glu Arg Val Pro Ala Thr Lys Thr Val His Leu Gln
            100                 105                 110

Ser Arg Ala Arg Tyr Thr Ser Glu Met Arg Ser Glu Leu Leu Gly Thr
        115                 120                 125

Asp Ser Ala Glu Pro Glu Met Asp Val Arg Lys Arg Thr Gly Val Ala
    130                 135                 140

Gly Ser Gln Pro Val Ser Glu Lys Gln Ser Ala Ala Glu Leu Asp Leu
145                 150                 155                 160

Val Leu Gln Arg His Gln Asn Leu Gln Glu Lys Leu Ala Glu Glu Met
                165                 170                 175

Leu Gly Leu Ala Arg Ser Leu Lys Thr Asn Thr Leu Ala Ala Gln Ser
            180                 185                 190

Val Ile Lys Lys Asp Asn Gln Thr Leu Ser His Ser Leu Lys Met Ala
        195                 200                 205

Asp Gln Asn Leu Glu Lys Leu Lys Thr Glu Ser Glu Arg Leu Glu Gln
    210                 215                 220

His Thr Gln Lys Ser Val Asn Trp Leu Leu Trp Ala Met Leu Ile Ile
225                 230                 235                 240

Val Cys Phe Ile Phe Ile Ser Met Ile Leu Phe Ile Arg Ile Met Pro
                245                 250                 255

Lys Leu Lys 




<210> 1777
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1777
Met Ala Ala Glu Met Glu Gln Ser Ser Gly Thr Gly Pro Ala Glu Leu
  1               5                  10                  15

Thr Gln Phe Trp Lys Glu Val Pro Arg Asn Lys Val Met Glu His Arg
             20                  25                  30

Leu Arg Cys His Thr Val Glu Ser Ser Lys Pro Asn Thr Leu Thr Leu
         35                  40                  45

Lys Asp Asn Ala Phe Asn Met Ser Asp Lys Thr Ser Glu Asp Ile Cys
     50                  55                  60

Leu Gln Leu Ser Arg Leu Leu Glu Ser Asn Arg Lys Leu Glu Asp Gln
 65                  70                  75                  80

Val Gln Arg Cys Ile Trp Phe Gln Gln Leu Leu Leu Ser Leu Thr Met
                 85                  90                  95

Leu Leu Leu Ala Phe Val Thr Ser Phe Phe Tyr Xaa Leu Tyr Ser 
            100                 105                 110



<210> 1778
<211> 410
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1778
Met Pro Asp Arg Arg His Ser Lys Ser Ala Gln Ile Ile Xaa Xaa Pro
  1               5                  10                  15

Val Pro Tyr Gln Xaa Xaa Ser His Thr Ser Tyr Leu Tyr Thr Gln Tyr
             20                  25                  30

Ala Pro Val Pro Phe Gly Ile Pro Xaa Pro Met Pro Xaa Pro Met Leu
         35                  40                  45

Ile Pro Ser Ser Met Asp Ser Glu Asp Lys Val Thr Glu Ser Ile Glu
     50                  55                  60

Asp Ile Lys Glu Lys Leu Pro Thr His Pro Phe Glu Ala Asp Leu Leu
 65                  70                  75                  80

Glu Met Ala Glu Met Ile Ala Glu Asp Glu Glu Lys Lys Thr Leu Ser
                 85                  90                  95

Gln Gly Glu Ser Gln Thr Ser Glu His Glu Leu Phe Leu Asp Thr Lys
            100                 105                 110

Ile Phe Glu Lys Xaa Gln Gly Ser Thr Tyr Ser Gly Asp Leu Glu Ser
        115                 120                 125

Glu Ala Val Ser Thr Pro His Ser Trp Glu Glu Glu Leu Asn His Tyr
    130                 135                 140

Ala Leu Lys Ser Asn Ala Val Gln Glu Ala Asp Ser Glu Leu Lys Gln
145                 150                 155                 160

Phe Ser Lys Gly Glu Thr Glu Arg Thr Trp Lys Gln Ile Phe His Gln
                165                 170                 175

Thr Pro Leu Thr His Leu Ile Lys Asp Gly Asn Pro Gly Thr Phe Pro
            180                 185                 190

Asn Arg Arg Arg His Arg Asp Gly Phe Pro Gln Pro Arg Arg Arg Gly
        195                 200                 205

Arg Lys Lys Ser Ile Val Ala Val Glu Pro Arg Ser Leu Ile Gln Gly
    210                 215                 220

Ala Phe Gln Gly Cys Ser Val Ser Gly Met Thr Xaa Lys Tyr Met Tyr
225                 230                 235                 240

Gly Val Asn Ala Trp Lys Asn Trp Val Gln Trp Lys Asn Ala Lys Glu
                245                 250                 255

Glu Gln Gly Asp Leu Lys Cys Gly Gly Val Glu Gln Ala Ser Ser Ser
            260                 265                 270

Pro Arg Ser Asp Pro Leu Gly Ser Thr Gln Asp His Ala Leu Ser Gln
        275                 280                 285

Glu Ser Ser Glu Pro Gly Cys Arg Val Arg Ser Ile Lys Leu Lys Glu
    290                 295                 300

Asp Ile Leu Ser Cys Thr Phe Ala Glu Leu Ser Leu Gly Leu Cys Gln
305                 310                 315                 320

Phe Ile Gln Glu Val Arg Arg Pro Asn Gly Glu Lys Tyr Asp Pro Asp
                325                 330                 335

Ser Ile Leu Tyr Leu Cys Leu Gly Ile Gln Gln Tyr Leu Phe Glu Asn
            340                 345                 350

Gly Arg Ile Asp Asn Ile Phe Thr Glu Pro Tyr Ser Arg Phe Met Ile
        355                 360                 365

Glu Leu Thr Lys Leu Leu Lys Ile Trp Glu Pro Thr Ile Leu Pro Asn
    370                 375                 380

Gly Tyr Met Phe Ser Arg Ile Glu Glu Glu His Leu Trp Glu Cys Lys
385                 390                 395                 400

Gln Leu Gly Ala Tyr Ser Pro Ile Ala Phe 
                405                 410



<210> 1779
<211> 158
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1779
Met Ser Thr Leu Cys Pro Pro Pro Ser Pro Ala Val Ala Lys Thr Glu
  1               5                  10                  15

Ile Ala Leu Ser Gly Lys Ser Pro Leu Leu Ala Ala Thr Phe Ala Tyr
             20                  25                  30

Trp Asp Asn Ile Leu Gly Pro Arg Val Arg His Ile Trp Ala Pro Lys
         35                  40                  45

Thr Glu Gln Val Leu Leu Ser Asp Gly Glu Ile Thr Phe Leu Ala Asn
     50                  55                  60

His Thr Leu Asn Gly Glu Ile Leu Arg Asn Ala Glu Ser Gly Ala Ile
 65                  70                  75                  80

Asp Val Lys Phe Phe Val Leu Ser Glu Lys Gly Val Ile Ile Val Ser
                 85                  90                  95

Leu Ile Phe Asp Gly Asn Trp Asn Gly Asp Arg Ser Thr Tyr Gly Leu
            100                 105                 110

Ser Ile Ile Leu Pro Gln Thr Glu Leu Ser Phe Tyr Leu Pro Leu His
        115                 120                 125

Arg Val Cys Val Asp Arg Leu Thr His Ile Ile Arg Lys Gly Arg Ile
    130                 135                 140

Trp Met His Lys Glu Arg Xaa Glu Met Ser Arg Arg Leu Ser 
145                 150                 155



<210> 1780
<211> 361
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1780
Met Val His Ala Glu Ala Phe Ser Arg Pro Leu Ser Arg Asn Glu Val
  1               5                  10                  15

Val Gly Leu Ile Phe Arg Leu Thr Ile Phe Gly Ala Val Thr Tyr Phe
             20                  25                  30

Thr Ile Lys Trp Met Val Asp Ala Ile Asp Pro Thr Arg Lys Gln Lys
         35                  40                  45

Val Glu Ala Gln Lys Gln Ala Glu Lys Leu Met Lys Gln Ile Gly Val
     50                  55                  60

Lys Asn Val Lys Leu Ser Glu Tyr Glu Met Ser Ile Ala Ala His Leu
 65                  70                  75                  80

Val Asp Pro Leu Asn Met His Val Thr Trp Ser Asp Ile Ala Gly Leu
                 85                  90                  95

Asp Asp Val Ile Thr Asp Leu Lys Asp Thr Val Ile Leu Pro Ile Lys
            100                 105                 110

Lys Xaa His Leu Phe Glu Asn Ser Arg Leu Leu Gln Pro Pro Lys Gly
        115                 120                 125

Val Leu Leu Tyr Gly Pro Pro Gly Cys Gly Lys Thr Leu Ile Ala Lys
    130                 135                 140

Ala Thr Ala Lys Glu Ala Gly Cys Arg Phe Ile Asn Leu Gln Pro Ser
145                 150                 155                 160

Thr Leu Thr Asp Lys Trp Tyr Gly Glu Ser Gln Lys Leu Ala Ala Ala
                165                 170                 175

Val Phe Ser Leu Ala Ile Lys Leu Gln Pro Ser Ile Ile Phe Ile Asp
            180                 185                 190

Glu Ile Asp Ser Phe Leu Arg Asn Arg Ser Ser Ser Asp His Glu Ala
        195                 200                 205

Thr Ala Met Met Lys Ala Gln Phe Met Ser Leu Trp Asp Gly Leu Asp
    210                 215                 220

Thr Asp His Ser Cys Gln Val Ile Val Met Gly Ala Xaa Asn Arg Pro
225                 230                 235                 240

Gln Asp Leu Asp Ser Ala Ile Met Arg Arg Met Pro Thr Arg Phe His
                245                 250                 255

Ile Asn Gln Pro Ala Leu Lys Gln Arg Glu Ala Ile Leu Lys Leu Ile
            260                 265                 270

Leu Lys Asn Glu Asn Val Asp Arg His Val Asp Leu Leu Glu Val Ala
        275                 280                 285

Gln Glu Thr Asp Gly Phe Ser Gly Ser Asp Leu Lys Glu Met Cys Arg
    290                 295                 300

Asp Ala Ala Leu Leu Cys Val Arg Glu Tyr Val Asn Ser Thr Ser Glu
305                 310                 315                 320

Glu Ser His Asp Glu Asp Glu Ile Arg Pro Val Gln Gln Gln Asp Leu
                325                 330                 335

His Arg Ala Ile Glu Lys Met Lys Lys Ser Lys Asp Ala Ala Phe Gln
            340                 345                 350

Asn Val Leu Thr His Val Cys Leu Asp 
        355                 360



<210> 1781
<211> 260
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (250)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (259)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1781
Met Leu Phe Leu Ala Leu Gly Ser Pro Trp Ala Val Glu Leu Xaa Leu
  1               5                  10                  15

Cys Gly Arg Arg Thr Ala Leu Cys Ala Ala Ala Ala Leu Arg Gly Pro
             20                  25                  30

Arg Ala Ser Val Ser Arg Ala Ser Ser Ser Ser Gly Pro Ser Gly Pro
         35                  40                  45

Val Ala Gly Trp Ser Thr Gly Pro Ser Gly Ala Ala Arg Leu Leu Arg
     50                  55                  60

Arg Pro Gly Arg Ala Gln Ile Pro Val Tyr Trp Glu Gly Tyr Val Arg
 65                  70                  75                  80

Phe Leu Asn Thr Pro Ser Asp Lys Ser Glu Asp Gly Arg Leu Ile Tyr
                 85                  90                  95

Thr Gly Asn Met Ala Arg Ala Val Phe Gly Val Lys Cys Phe Ser Tyr
            100                 105                 110

Ser Thr Ser Leu Ile Gly Leu Thr Phe Leu Pro Tyr Ile Phe Thr Gln
        115                 120                 125

Asn Asn Ala Ile Ser Glu Ser Val Pro Leu Pro Ile Gln Ile Ile Phe
    130                 135                 140

Tyr Gly Ile Met Gly Ser Phe Thr Val Ile Thr Pro Val Leu Leu His
145                 150                 155                 160

Phe Ile Thr Lys Gly Tyr Val Ile Arg Leu Tyr His Glu Ala Thr Thr
                165                 170                 175

Asp Thr Tyr Lys Ala Ile Thr Tyr Asn Ala Met Leu Ala Glu Thr Ser
            180                 185                 190

Thr Val Phe His Gln Asn Asp Val Lys Ile Pro Asp Ala Lys His Val
        195                 200                 205

Phe Thr Thr Phe Tyr Ala Lys Thr Lys Ser Leu Leu Val Asn Pro Val
    210                 215                 220

Leu Phe Pro Asn Arg Glu Asp Tyr Ile His Leu Met Gly Tyr Asp Lys
225                 230                 235                 240

Glu Glu Phe Ile Leu Tyr Met Glu Glu Xaa Ser Glu Glu Lys Arg His
                245                 250                 255

Lys Asp Xaa Lys 
            260



<210> 1782
<211> 219
<212> PRT
<213> Homo sapiens

<400> 1782
Met Pro Arg Gly Arg Lys Ser Arg Arg Arg Arg Asn Ala Arg Ala Ala
  1               5                  10                  15

Glu Glu Asn Arg Asn Asn Arg Lys Ile Gln Ala Ser Glu Ala Ser Glu
             20                  25                  30

Thr Pro Met Ala Ala Ser Val Val Ala Ser Thr Pro Glu Asp Asp Leu
         35                  40                  45

Ser Gly Pro Glu Glu Asp Pro Ser Thr Pro Glu Glu Ala Ser Thr Thr
     50                  55                  60

Pro Glu Glu Ala Ser Ser Thr Ala Gln Ala Gln Lys Pro Ser Val Pro
 65                  70                  75                  80

Arg Ser Asn Phe Gln Gly Thr Lys Lys Ser Leu Leu Met Ser Ile Leu
                 85                  90                  95

Ala Leu Ile Phe Ile Met Gly Asn Ser Ala Lys Glu Ala Leu Val Trp
            100                 105                 110

Lys Val Leu Gly Lys Leu Gly Met Gln Pro Gly Arg Gln His Ser Ile
        115                 120                 125

Phe Gly Asp Pro Lys Lys Ile Val Thr Glu Glu Phe Val Arg Arg Gly
    130                 135                 140

Tyr Leu Ile Tyr Lys Pro Val Pro Arg Ser Ser Pro Val Glu Tyr Glu
145                 150                 155                 160

Phe Phe Trp Gly Pro Arg Ala His Val Glu Ser Ser Lys Leu Lys Val
                165                 170                 175

Met His Phe Val Ala Arg Val Arg Asn Arg Cys Ser Lys Asp Trp Pro
            180                 185                 190

Cys Asn Tyr Asp Trp Asp Ser Asp Asp Asp Ala Glu Val Glu Ala Ile
        195                 200                 205

Leu Asn Ser Gly Ala Arg Gly Tyr Ser Ala Pro 
    210                 215



<210> 1783
<211> 148
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1783
Met Thr Ala Val Ala Asp Ile Phe Asp Arg Asp Gly Asp Gly Tyr Ile
  1               5                  10                  15

Asp Tyr Tyr Glu Phe Val Ala Ala Leu His Pro Asn Lys Asp Ala Tyr
             20                  25                  30

Arg Pro Thr Thr Asp Ala Asp Lys Ile Glu Glu Arg Leu Gln Asp Lys
         35                  40                  45

Trp Leu Ser Ala Asn Val Gln Lys Gly Phe Arg Trp Ser Arg Ser Glu
     50                  55                  60

Arg Ile Asn Thr Gly Leu Gly Ile Leu Ser Ser Cys Gly Trp Ser Val
 65                  70                  75                  80

Phe Cys Ala Thr Val Met Val Arg Val Gly Gly Gly Trp Met Ala Leu
                 85                  90                  95

Asp Glu Phe Leu Val Lys Asn Asp Pro Cys Arg Ala Arg Gly Arg Thr
            100                 105                 110

Asn Ile Glu Leu Arg Glu Lys Phe Ile Leu Pro Xaa Gly Ala Xaa Gln
        115                 120                 125

Gly Met Thr Pro Phe Arg Ser Arg Gly Arg Ser Pro Asn His Leu Pro
    130                 135                 140

Gly Gln Leu Pro 
145



<210> 1784
<211> 184
<212> PRT
<213> Homo sapiens

<400> 1784
Met Met Pro Ser Ser Cys Pro Trp Arg Thr Gly Ala Leu Gly Glu Ser
  1               5                  10                  15

Ser Gly Val Ala Arg Phe Gly Pro Leu His Phe Glu Arg Arg Ala Arg
             20                  25                  30

Phe Glu Val Ala Asp Glu Asp Lys Gln Ser Arg Leu Arg Tyr Gln Asn
         35                  40                  45

Leu Glu Asn Asp Glu Asp Gly Ala Gln Ala Ser Pro Glu Pro Asp Gly
     50                  55                  60

Gly Val Gly Thr Arg Asp Ser Ser Arg Thr Ser Ile Arg Ser Ser Gln
 65                  70                  75                  80

Trp Ser Phe Ser Thr Ile Ser Ser Ser Thr Gln Arg Ser Tyr Asn Thr
                 85                  90                  95

Cys Cys Ser Trp Thr Gln His Pro Leu Ile Gln Lys Asn Arg Arg Val
            100                 105                 110

Val Leu Ala Ser Phe Leu Leu Leu Leu Leu Gly Leu Val Leu Ile Leu
        115                 120                 125

Val Gly Val Gly Leu Glu Ala Thr Pro Ser Pro Gly Val Ser Ser Ala
    130                 135                 140

Ile Phe Phe Val Pro Gly Phe Leu Leu Leu Val Pro Gly Val Tyr His
145                 150                 155                 160

Val Ile Phe Ile Tyr Cys Ala Val Lys Gly His Arg Gly Phe Gln Phe
                165                 170                 175

Phe Tyr Leu Pro Tyr Phe Glu Lys 
            180



<210> 1785
<211> 333
<212> PRT
<213> Homo sapiens

<400> 1785
Met Gly Leu Arg Arg Ser Gly Lys Ser Ser Ile Gln Lys Val Val Phe
  1               5                  10                  15

His Lys Met Ser Pro Asn Glu Thr Leu Phe Leu Glu Ser Thr Asn Lys
             20                  25                  30

Ile Tyr Lys Asp Asp Ile Ser Asn Ser Ser Phe Val Asn Phe Gln Ile
         35                  40                  45

Trp Asp Phe Pro Gly Gln Met Asp Phe Phe Asp Pro Thr Phe Asp Tyr
     50                  55                  60

Glu Met Ile Phe Arg Gly Thr Gly Ala Leu Ile Tyr Val Ile Asp Ala
 65                  70                  75                  80

Gln Asp Asp Tyr Met Glu Ala Leu Thr Arg Leu His Ile Thr Val Ser
                 85                  90                  95

Lys Ala Tyr Lys Val Asn Pro Asp Met Asn Phe Glu Val Phe Ile His
            100                 105                 110

Lys Val Asp Gly Leu Ser Asp Asp His Lys Ile Glu Thr Gln Arg Asp
        115                 120                 125

Ile His Gln Arg Ala Asn Asp Asp Leu Ala Asp Ala Gly Leu Glu Lys
    130                 135                 140

Leu His Leu Ser Phe Tyr Leu Thr Ser Ile Tyr Asp His Ser Ile Phe
145                 150                 155                 160

Glu Ala Phe Ser Lys Val Val Gln Lys Leu Ile Pro Gln Leu Pro Thr
                165                 170                 175

Leu Glu Asn Leu Leu Asn Ile Phe Ile Ser Asn Ser Gly Ile Glu Lys
            180                 185                 190

Ala Phe Leu Phe Asp Val Val Ser Lys Ile Tyr Ile Ala Thr Asp Ser
        195                 200                 205

Ser Pro Val Asp Met Gln Ser Tyr Glu Leu Cys Cys Asp Met Ile Asp
    210                 215                 220

Val Val Ile Asp Val Ser Cys Ile Tyr Gly Leu Lys Glu Asp Gly Ser
225                 230                 235                 240

Gly Ser Ala Tyr Asp Lys Glu Ser Met Ala Ile Ile Lys Leu Asn Asn
                245                 250                 255

Thr Thr Val Leu Tyr Leu Lys Glu Val Thr Lys Phe Leu Ala Leu Val
            260                 265                 270

Cys Ile Leu Arg Glu Glu Ser Phe Glu Arg Lys Gly Leu Ile Asp Tyr
        275                 280                 285

Asn Phe His Cys Phe Arg Lys Ala Ile His Glu Val Phe Glu Val Gly
    290                 295                 300

Val Thr Ser His Arg Ser Cys Gly His Gln Thr Ser Ala Ser Ser Leu
305                 310                 315                 320

Lys Ala Leu Thr His Asn Gly Thr Pro Arg Asn Ala Ile 
                325                 330



<210> 1786
<211> 170
<212> PRT
<213> Homo sapiens

<400> 1786
Met Ser Val Ala Gly Gly Glu Ile Arg Gly Asp Thr Gly Gly Glu Asp
  1               5                  10                  15

Thr Ala Ala Pro Gly Arg Phe Ser Phe Ser Pro Glu Pro Thr Leu Glu
             20                  25                  30

Asp Ile Arg Arg Leu His Ala Glu Phe Ala Ala Glu Arg Asp Trp Glu
         35                  40                  45

Gln Phe His Gln Pro Arg Asn Leu Leu Leu Ala Leu Val Gly Glu Val
     50                  55                  60

Gly Glu Leu Ala Glu Leu Phe Gln Trp Lys Thr Asp Gly Glu Pro Gly
 65                  70                  75                  80

Pro Gln Gly Trp Ser Pro Arg Glu Arg Ala Ala Leu Gln Glu Glu Leu
                 85                  90                  95

Ser Asp Val Leu Ile Tyr Leu Val Ala Leu Ala Ala Arg Cys Arg Val
            100                 105                 110

Asp Leu Pro Leu Ala Val Leu Ser Lys Met Asp Ile Asn Arg Arg Arg
        115                 120                 125

Tyr Pro Ala His Leu Ala Arg Ser Ser Ser Arg Lys Tyr Thr Glu Leu
    130                 135                 140

Pro His Gly Ala Ile Ser Glu Asp Gln Ala Val Gly Pro Ala Asp Ile
145                 150                 155                 160

Pro Cys Asp Ser Thr Gly Gln Thr Ser Thr 
                165                 170



<210> 1787
<211> 207
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1787
Met Asn Asn Gln Lys Val Val Ala Val Leu Leu Gln Glu Cys Lys Gln
  1               5                  10                  15

Val Leu Xaa Gln Leu Leu Leu Glu Ala Pro Asp Val Ser Glu Glu Asp
             20                  25                  30

Lys Ser Glu Asp Gln Arg Cys Arg Ala Leu Leu Pro Ser Glu Leu Arg
         35                  40                  45

Thr Leu Ile Gln Glu Ala Lys Glu Met Lys Trp Pro Phe Val Pro Glu
     50                  55                  60

Lys Trp Gln Tyr Lys Gln Ala Val Gly Pro Glu Asp Lys Thr Asn Leu
 65                  70                  75                  80

Lys Asp Val Ile Gly Ala Gly Leu Gln Gln Leu Leu Ala Ser Leu Arg
                 85                  90                  95

Ala Ser Ile Leu Ala Arg Asp Cys Ala Ala Ala Ala Ala Ile Val Phe
            100                 105                 110

Leu Val Asp Arg Phe Leu Tyr Gly Xaa Asp Val Ser Gly Lys Leu Leu
        115                 120                 125

Gln Val Ala Lys Gly Leu His Lys Leu Gln Pro Ala Thr Pro Ile Ala
    130                 135                 140

Pro Gln Val Val Ile Arg Gln Ala Arg Ile Ser Val Asn Ser Gly Lys
145                 150                 155                 160

Leu Leu Lys Ala Glu Tyr Ile Leu Ser Ser Leu Ile Ser Asn Asn Gly
                165                 170                 175

Ala Thr Gly Thr Trp Leu Tyr Arg Asn Glu Ser Asp Lys Val Leu Val
            180                 185                 190

Gln Ser Val Cys Ile Gln Ile Arg Gly Gln Ile Leu Gln Lys Leu 
        195                 200                 205



<210> 1788
<211> 209
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (192)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1788
Met Gly Gly Lys Gln Leu Asp Glu Asp Asp Glu Ala Tyr Gly Lys Pro
  1               5                  10                  15

Val Lys Xaa Asp Pro Ser Phe Arg Gly Pro Ile Lys Asn Arg Ser Cys
             20                  25                  30

Thr Asp Val Ile Cys Cys Val Leu Phe Leu Leu Phe Ile Leu Gly Tyr
         35                  40                  45

Ile Val Val Gly Ile Val Ala Trp Leu Tyr Gly Asp Pro Arg Gln Val
     50                  55                  60

Leu Tyr Pro Arg Asn Ser Thr Gly Ala Tyr Cys Gly Met Gly Glu Asn
 65                  70                  75                  80

Lys Asp Lys Pro Tyr Leu Leu Tyr Phe Asn Ile Phe Ser Cys Ile Leu
                 85                  90                  95

Ser Ser Asn Ile Ile Ser Val Ala Glu Asn Gly Leu Gln Cys Pro Thr
            100                 105                 110

Pro Gln Val Cys Val Ser Ser Cys Pro Glu Asp Pro Trp Thr Val Gly
        115                 120                 125

Lys Asn Glu Phe Ser Gln Thr Val Gly Glu Val Phe Tyr Thr Lys Asn
    130                 135                 140

Arg Asn Phe Cys Leu Pro Gly Val Pro Trp Asn Met Thr Val Ile Thr
145                 150                 155                 160

Ser Leu Gln Gln Glu Leu Cys Pro Val Ser Ser Ser Leu Cys Ser Ala
                165                 170                 175

Leu Xaa Arg Cys Phe His Gly Pro Thr Leu Leu His Arg Xaa Leu Xaa
            180                 185                 190

Gly Ile Thr Asn Asp His Pro Pro Tyr Ser Arg Gly Ile Ser Gly Leu
        195                 200                 205

Tyr 




<210> 1789
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1789
Met Glu Met Ile Ala Phe Ala Arg Ile Phe Cys Lys Gly Gln Val Ser
  1               5                  10                  15

Thr Ala Thr Phe Leu Glu Ser Cys Xaa Val Ala Asp Leu Ile Thr Thr
             20                  25                  30

Cys Tyr Gly Gly Arg Asn Arg Arg Val Ala Xaa Ala Phe Ala Arg Thr
         35                  40                  45

Gly Lys Gly Ser Pro Ser Leu Leu Ser Ala Pro Pro Leu Xaa His Leu
     50                  55                  60

Arg Leu Leu Leu Gly Val Asn Trp Asn Pro Trp Arg Phe Met Pro Xaa
 65                  70                  75                  80

Leu Leu Leu Gly Trp Ser Val Ala Cys Cys Phe Tyr Leu Thr Leu Trp
                 85                  90                  95

Ser Tyr Leu Trp Xaa Leu Thr Ser Trp Phe 
            100                 105



<210> 1790
<211> 279
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1790
Met Ser Phe Asn Leu Gln Ser Ser Lys Lys Leu Phe Ile Phe Leu Gly
  1               5                  10                  15

Lys Ser Leu Phe Ser Leu Leu Glu Ala Met Ile Phe Ala Leu Leu Pro
             20                  25                  30

Lys Pro Arg Lys Asn Val Ala Gly Glu Ile Val Leu Ile Thr Gly Ala
         35                  40                  45

Gly Ser Gly Leu Gly Arg Leu Leu Ala Leu Gln Phe Ala Arg Leu Gly
     50                  55                  60

Ser Val Leu Val Leu Trp Asp Ile Asn Lys Glu Gly Asn Glu Glu Thr
 65                  70                  75                  80

Cys Lys Met Ala Arg Glu Ala Gly Ala Thr Arg Val His Ala Tyr Thr
                 85                  90                  95

Cys Asp Cys Ser Gln Lys Glu Gly Val Tyr Arg Val Xaa Asp Gln Val
            100                 105                 110

Lys Lys Glu Val Gly Asp Val Ser Ile Leu Ile Asn Asn Ala Gly Ile
        115                 120                 125

Val Thr Gly Lys Lys Phe Leu Asp Cys Pro Asp Glu Leu Met Glu Lys
    130                 135                 140

Ser Phe Asp Val Asn Phe Lys Ala His Leu Trp Thr Tyr Lys Ala Phe
145                 150                 155                 160

Leu Pro Ala Met Ile Ala Asn Asp His Gly His Leu Val Cys Ile Ser
                165                 170                 175

Ser Ser Ala Gly Leu Ser Gly Val Asn Gly Leu Ala Asp Tyr Cys Ala
            180                 185                 190

Ser Lys Phe Ala Ala Phe Gly Phe Ala Glu Ser Val Phe Val Glu Thr
        195                 200                 205

Phe Val Gln Lys Gln Lys Gly Ile Lys Thr Thr Ile Val Cys Pro Phe
    210                 215                 220

Phe Ile Lys Thr Gly Met Xaa Glu Gly Cys Thr Thr Gly Cys Pro Ser
225                 230                 235                 240

Leu Leu Pro Ile Leu Glu Pro Lys Tyr Ala Val Glu Lys Ile Val Glu
                245                 250                 255

Ala Ile Leu Gln Glu Lys Met Tyr Leu Tyr Met Pro Lys Leu Leu Tyr
            260                 265                 270

Phe Met Met Phe Leu Lys Arg 
        275



<210> 1791
<211> 397
<212> PRT
<213> Homo sapiens

<400> 1791
Met Ala Leu Leu Arg Gly Val Phe Val Val Ala Ala Lys Arg Thr Pro
  1               5                  10                  15

Phe Gly Ala Tyr Gly Gly Leu Leu Lys Asp Phe Thr Ala Thr Asp Leu
             20                  25                  30

Ser Glu Phe Ala Ala Lys Ala Ala Leu Ser Ala Gly Lys Val Ser Pro
         35                  40                  45

Glu Thr Val Asp Ser Val Ile Met Gly Asn Val Leu Gln Ser Ser Ser
     50                  55                  60

Asp Ala Ile Tyr Leu Ala Arg His Val Gly Leu Arg Val Gly Ile Pro
 65                  70                  75                  80

Lys Glu Thr Pro Ala Leu Thr Ile Asn Arg Leu Cys Gly Ser Gly Phe
                 85                  90                  95

Gln Ser Ile Val Asn Gly Cys Gln Glu Ile Cys Val Lys Glu Ala Glu
            100                 105                 110

Val Val Leu Cys Gly Gly Thr Glu Ser Met Ser Gln Ala Pro Tyr Cys
        115                 120                 125

Val Arg Asn Val Arg Phe Gly Thr Lys Leu Gly Ser Asp Ile Lys Leu
    130                 135                 140

Glu Asp Ser Leu Trp Val Ser Leu Thr Asp Gln His Val Gln Leu Pro
145                 150                 155                 160

Met Ala Met Thr Ala Glu Asn Leu Ala Val Lys His Lys Ile Ser Arg
                165                 170                 175

Glu Glu Cys Asp Lys Tyr Ala Leu Gln Ser Gln Gln Arg Trp Lys Ala
            180                 185                 190

Ala Asn Asp Ala Gly Tyr Phe Asn Asp Glu Met Ala Pro Ile Glu Val
        195                 200                 205

Lys Thr Lys Lys Gly Lys Gln Thr Met Gln Val Asp Glu His Ala Arg
    210                 215                 220

Pro Gln Thr Thr Leu Glu Gln Leu Gln Lys Leu Pro Pro Val Phe Lys
225                 230                 235                 240

Lys Asp Gly Thr Val Thr Ala Gly Asn Ala Ser Gly Val Ala Asp Gly
                245                 250                 255

Ala Gly Ala Val Ile Ile Ala Ser Glu Asp Ala Val Lys Lys His Asn
            260                 265                 270

Phe Thr Pro Leu Ala Arg Ile Val Gly Tyr Phe Val Ser Gly Cys Asp
        275                 280                 285

Pro Ser Ile Met Gly Ile Gly Pro Val Pro Ala Ile Ser Gly Ala Leu
    290                 295                 300

Lys Lys Ala Gly Leu Ser Leu Lys Asp Met Asp Leu Val Glu Val Asn
305                 310                 315                 320

Glu Ala Phe Ala Pro Gln Tyr Leu Ala Val Glu Arg Ser Leu Asp Leu
                325                 330                 335

Asp Ile Ser Lys Thr Asn Val Asn Gly Gly Ala Ile Ala Leu Gly His
            340                 345                 350

Pro Leu Gly Gly Ser Gly Ser Arg Ile Thr Ala His Leu Val His Glu
        355                 360                 365

Leu Arg Arg Arg Gly Gly Lys Tyr Ala Val Gly Ser Ala Cys Ile Gly
    370                 375                 380

Gly Gly Gln Gly Ile Ala Val Ile Ile Gln Ser Thr Ala 
385                 390                 395



<210> 1792
<211> 111
<212> PRT
<213> Homo sapiens

<400> 1792
Met Phe Arg Pro Pro Arg Thr Ser His Cys Ser Val Cys Asp Asn Cys
  1               5                  10                  15

Val Glu Arg Phe Asp His His Cys Pro Trp Val Gly Asn Cys Val Gly
             20                  25                  30

Arg Arg Asn Tyr Arg Phe Phe Tyr Ala Phe Ile Leu Ser Leu Ser Phe
         35                  40                  45

Leu Thr Ala Phe Ile Phe Ala Cys Val Val Thr His Leu Thr Leu Arg
     50                  55                  60

Ala Gln Gly Ser Asn Phe Leu Ser Thr Leu Lys Glu Thr Pro Ala Ser
 65                  70                  75                  80

Val Leu Gly Val Gly Asp Leu Leu Leu Leu His Leu Val His Ser Gly
                 85                  90                  95

Pro Leu Arg Val Ser His Val Pro Arg Arg Leu Gln Pro Asp Tyr 
            100                 105                 110



<210> 1793
<211> 113
<212> PRT
<213> Homo sapiens

<400> 1793
Met Leu Trp Trp Met Arg Leu Glu Phe Glu Arg Arg Ser Lys Arg Trp
  1               5                  10                  15

Pro Gly Leu Glu Arg Thr Glu Val Phe Pro Ile His Phe Ser Arg Lys
             20                  25                  30

Leu Pro Arg Gln Arg Gln Lys Glu Met Asp Asp Ser Ser Val Lys His
         35                  40                  45

Thr Ser Val Leu Leu Glu Leu Arg Ser Val Ser Lys Arg Thr Glu Val
     50                  55                  60

Ile Arg Glu Thr Val Thr Cys Gly Ile Gln His Leu Trp Leu Glu Arg
 65                  70                  75                  80

Ile Gly Phe Phe Phe Leu Val Leu Ile Glu Met Glu Leu Ser Lys Ser
                 85                  90                  95

Ser Phe Cys Leu Phe Cys Cys Leu Gln Ile Leu Cys Leu Leu Phe Leu
            100                 105                 110

Ile 




<210> 1794
<211> 389
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1794
Met Ser Lys Tyr Ser Ala Gly Xaa Ile Tyr Tyr Tyr Pro Ser Phe His
  1               5                  10                  15

Tyr Thr His Asn Pro Ser Gln Ala Glu Lys Leu Gln Lys Asp Leu Lys
             20                  25                  30

Arg Tyr Leu Thr Arg Lys Ile Gly Phe Glu Ala Val Met Arg Ile Arg
         35                  40                  45

Cys Thr Lys Gly Leu Ser Met His Thr Phe His Gly Asn Phe Phe Val
     50                  55                  60

Arg Ser Thr Asp Leu Leu Ser Leu Ala Asn Ile Asn Pro Asp Ala Gly
 65                  70                  75                  80

Phe Ala Val Gln Leu Ser Ile Glu Glu Ser Leu Thr Asp Thr Ser Leu
                 85                  90                  95

Val Cys Phe Gln Thr Ala Leu Leu Tyr Thr Ser Ser Lys Gly Glu Arg
            100                 105                 110

Arg Ile Arg Val His Thr Leu Cys Leu Pro Val Val Ser Ser Leu Ala
        115                 120                 125

Asp Val Tyr Ala Gly Val Asp Val Gln Ala Ala Ile Cys Leu Leu Ala
    130                 135                 140

Asn Met Ala Val Asp Arg Ser Val Ser Ser Ser Leu Ser Asp Ala Arg
145                 150                 155                 160

Asp Ala Leu Val Asn Ala Val Val Asp Ser Leu Ser Ala Tyr Gly Ser
                165                 170                 175

Thr Val Ser Asn Leu Gln His Ser Ala Leu Met Ala Pro Ser Ser Leu
            180                 185                 190

Lys Leu Phe Pro Leu Tyr Val Leu Ala Leu Leu Lys Gln Lys Ala Phe
        195                 200                 205

Arg Thr Gly Thr Ser Thr Arg Leu Asp Asp Arg Val Tyr Ala Met Cys
    210                 215                 220

Gln Ile Lys Ser Gln Pro Leu Val His Leu Met Lys Met Ile His Pro
225                 230                 235                 240

Asn Leu Tyr Arg Ile Asp Arg Leu Thr Asp Glu Gly Ala Val His Val
                245                 250                 255

Asn Asp Arg Ile Val Pro Gln Pro Pro Leu Gln Lys Leu Ser Ala Glu
            260                 265                 270

Lys Leu Thr Arg Glu Gly Ala Phe Leu Met Asp Cys Gly Ser Val Phe
        275                 280                 285

Tyr Ile Trp Val Gly Lys Gly Cys Asp Asn Asn Phe Ile Glu Asp Val
    290                 295                 300

Leu Gly Tyr Thr Asn Phe Ala Ser Ile Pro Gln Lys Met Thr His Leu
305                 310                 315                 320

Pro Glu Leu Asp Thr Leu Ser Ser Glu Arg Ala Arg Ser Phe Ile Thr
                325                 330                 335

Trp Leu Arg Asp Ser Arg Pro Leu Ser Pro Ile Leu His Ile Val Lys
            340                 345                 350

Asp Glu Ser Pro Ala Lys Ala Glu Phe Phe Gln His Leu Ile Glu Asp
        355                 360                 365

Arg Thr Glu Ala Ala Phe Ser Tyr Tyr Glu Phe Leu Leu His Val Gln
    370                 375                 380

Gln Gln Ile Cys Lys 
385



<210> 1795
<211> 194
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (164)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1795
Met Leu Lys Cys Ser Ser Cys Gln Ala Phe Leu Cys Ala Ser Leu Gln
  1               5                  10                  15

Pro Ala Phe Asp Phe Asp Arg Tyr Lys Gln Arg Cys Ala Glu Leu Lys
             20                  25                  30

Lys Ala Leu Cys Thr Ala His Glu Lys Phe Cys Phe Trp Pro Asp Ser
         35                  40                  45

Pro Ser Pro Asp Arg Phe Gly Met Leu Pro Leu Asp Glu Pro Ala Ile
     50                  55                  60

Leu Val Ser Glu Phe Leu Asp Arg Phe Gln Ser Leu Cys His Leu Asp
 65                  70                  75                  80

Leu Gln Leu Pro Ser Leu Arg Pro Glu Asp Leu Lys Thr Met Cys Leu
                 85                  90                  95

Thr Glu Asp Lys Ile Ser Leu Leu Leu His Leu Leu Glu Asp Glu Leu
            100                 105                 110

Asp His Arg Thr Asp Glu Arg Lys Thr Thr Ile Lys Leu Gly Ser Asp
        115                 120                 125

Ile Gln Val His Val Thr Ala Cys Ile Leu Ser Val Cys Gly Trp Ala
    130                 135                 140

Cys Ser Ser Ser Leu Glu Ser Met Gln Leu Ser Leu Ile Xaa Cys Ser
145                 150                 155                 160

Gln Cys Met Xaa Lys Val Gly Leu Trp Gly Phe Gln Gln Ile Glu Ser
                165                 170                 175

Ser Met Thr Asp Leu Asp Ala Ser Leu Pro Asp Gln Leu Pro Asn Pro
            180                 185                 190

Arg Pro 




<210> 1796
<211> 113
<212> PRT
<213> Homo sapiens

<400> 1796
Met Val Lys Leu Gly Pro Pro Thr Leu Ser Leu Pro Arg Pro Leu Asp
  1               5                  10                  15

Ser Gln Met Gln Gly Pro Trp Leu Trp Pro Leu Thr Pro Lys Ala Val
             20                  25                  30

Ser Gly Pro Ala Glu Pro Met Gly Val Pro Gly Gln Ser Ala His Ser
         35                  40                  45

Pro Leu Leu Ala Ala Leu Gly Leu Pro Thr Phe Pro Gly Val Ser Thr
     50                  55                  60

Phe Pro Leu Val Gly Leu Met Cys Val Cys Val Phe Ser Leu Asn Thr
 65                  70                  75                  80

Arg Pro Gly Val Cys Ser His Thr Cys Ala Gln Val Cys Thr Leu Lys
                 85                  90                  95

Phe Ser Trp Ala Gly Ser Gly Leu Ser Arg Cys Pro Gly His Glu Val
            100                 105                 110

Ser 




<210> 1797
<211> 292
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1797
Met Ser Ser Leu Tyr Pro Ser Leu Glu Asp Leu Lys Val Asp Gln Ala
  1               5                  10                  15

Ile Gln Ala Gln Val Arg Ala Ser Pro Lys Met Pro Ala Leu Pro Val
             20                  25                  30

Gln Ala Thr Ala Ile Ser Pro Pro Pro Val Leu Tyr Pro Asn Leu Ala
         35                  40                  45

Glu Leu Glu Asn Tyr Met Gly Leu Ser Leu Ser Ser Gln Glu Val Gln
     50                  55                  60

Glu Ser Leu Leu Gln Ile Pro Glu Gly Asp Ser Thr Ala Val Ser Gly
 65                  70                  75                  80

Pro Gly Pro Gly Gln Met Val Ala Pro Val Thr Gly Tyr Ser Leu Gly
                 85                  90                  95

Val Arg Arg Ala Glu Ile Lys Pro Gly Val Arg Glu Ile His Leu Cys
            100                 105                 110

Lys Asp Glu Arg Gly Lys Thr Gly Leu Arg Leu Arg Lys Val Asp Gln
        115                 120                 125

Gly Leu Phe Val Gln Leu Val Gln Ala Asn Thr Pro Ala Ser Leu Val
    130                 135                 140

Gly Leu Arg Phe Gly Asp Gln Leu Leu Gln Ile Asp Gly Arg Asp Cys
145                 150                 155                 160

Ala Gly Trp Ser Ser His Lys Ala His Gln Val Val Lys Lys Ala Ser
                165                 170                 175

Gly Asp Lys Ile Val Val Val Val Arg Asp Arg Pro Phe Gln Arg Thr
            180                 185                 190

Val Thr Met His Lys Asp Ser Met Gly His Val Gly Phe Val Ile Lys
        195                 200                 205

Lys Gly Lys Ile Val Ser Leu Val Lys Gly Ser Ser Ala Ala Xaa Asn
    210                 215                 220

Gly Leu Leu Thr Asn His Tyr Val Cys Glu Val Asp Gly Gln Asn Val
225                 230                 235                 240

Ile Gly Leu Lys Asp Lys Lys Ile Met Glu Ile Leu Ala Thr Ala Gly
                245                 250                 255

Asn Val Val Thr Leu Thr Ile Ile Pro Ser Val Ile Tyr Glu His Met
            260                 265                 270

Val Lys Lys Leu Pro Pro Val Leu Leu His His Thr Met Asp His Ser
        275                 280                 285

Ile Pro Asp Ala 
    290



<210> 1798
<211> 138
<212> PRT
<213> Homo sapiens

<400> 1798
Met Glu Pro His Phe Arg Ile Ile Phe Ser Val Ser Leu Tyr Gln Gln
  1               5                  10                  15

Lys Glu Gln Cys His Arg Glu Trp Asn Ser Leu Gly Lys Ala Leu Pro
             20                  25                  30

Asn Thr Thr Leu Ile Ser Glu Gln Glu His Gly Leu Asp Arg Ser Ser
         35                  40                  45

Val Pro Leu Glu Leu Phe Cys Tyr Cys Ala Val Ile Phe Arg Arg Phe
     50                  55                  60

Pro Phe Leu Cys Arg Cys Cys Trp Glu Phe Gly Ile Met Phe Ile Ser
 65                  70                  75                  80

Ser Val Leu Met Ala Phe Ser Thr Asn Phe Ile Ser Ala Ser Cys Val
                 85                  90                  95

Asn Leu Asn Lys Phe Ser Phe Val Ile Phe Phe Lys Lys Val Thr Glu
            100                 105                 110

Phe Ile Leu Ile Phe Thr Ile Val Phe Gly Arg Val Asn Phe Pro Leu
        115                 120                 125

Tyr Asn Lys Tyr Leu Phe Val Ile His Lys 
    130                 135



<210> 1799
<211> 173
<212> PRT
<213> Homo sapiens

<400> 1799
Met Asn Thr Gly Asn Glu Gly Leu Pro Thr Ser Gly Ser Phe Thr Leu
  1               5                  10                  15

Asp Asp Asp Val Phe Ala Glu Thr Glu Glu Pro Ser Ser Pro Thr Gly
             20                  25                  30

Val Leu Val Asn Ser Asn Leu Pro Ile Ala Ser Ile Ser Asp Tyr Arg
         35                  40                  45

Leu Leu Cys Asp Ile Asn Lys Tyr Val Cys Asn Lys Ile Ser Leu Leu
     50                  55                  60

Pro Asn Asp Glu Asp Ser Leu Pro Pro Leu Leu Val Ala Ser Gly Glu
 65                  70                  75                  80

Lys Gly Ser Val Pro Val Val Glu Glu His Pro Ser His Glu Gln Ile
                 85                  90                  95

Ile Leu Leu Leu Glu Gly Glu Gly Phe His Pro Val Thr Phe Val Leu
            100                 105                 110

Asn Ala Asn Leu Leu Val Asn Val Lys Phe Ile Phe Tyr Ser Ser Asp
        115                 120                 125

Lys Tyr Gly Thr Phe Gln Pro Met Asp Cys Arg Leu Gly Gln Gly Arg
    130                 135                 140

Ile Ile Ile Tyr Cys Tyr Val Cys Gln Met Lys Ile Leu Phe Leu Arg
145                 150                 155                 160

Thr Ser Ser Asp Tyr Leu Ser Pro Tyr Ile Arg Met Leu 
                165                 170



<210> 1800
<211> 456
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (147)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (222)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1800
Met Val Phe Gly Ile Phe Leu Cys Leu Asp Ala Phe Leu Tyr Val Phe
  1               5                  10                  15

Thr Leu Leu Pro Leu Arg Val Phe Leu Ala Leu Phe Arg Leu Leu Thr
             20                  25                  30

Leu Pro Cys Tyr Gly Leu Arg Asp Arg Arg Leu Leu Gln Pro Ala Gln
         35                  40                  45

Val Cys Asp Ile Leu Lys Gly Val Ile Leu Val Ile Cys Tyr Phe Met
     50                  55                  60

Met His Tyr Val Asp Tyr Ser Met Met Tyr His Leu Ile Arg Gly Gln
 65                  70                  75                  80

Ser Val Ile Lys Leu Tyr Ile Ile Tyr Asn Met Leu Glu Val Ala Asp
                 85                  90                  95

Arg Leu Phe Ser Ser Phe Gly Gln Asp Ile Leu Asp Ala Leu Tyr Trp
            100                 105                 110

Thr Ala Thr Glu Pro Lys Glu Arg Lys Arg Ala His Ile Gly Val Ile
        115                 120                 125

Pro His Phe Phe Met Ala Val Leu Tyr Val Phe Leu His Ala Ile Leu
    130                 135                 140

Ile Met Xaa Gln Ala Thr Thr Leu Asn Val Ala Phe Asn Ser His Asn
145                 150                 155                 160

Lys Ser Leu Ser Thr Ile Met Met Ser Asn Asn Xaa Val Glu Ile Lys
                165                 170                 175

Gly Ser Val Phe Lys Lys Phe Glu Lys Asn Asn Leu Phe Gln Met Ser
            180                 185                 190

Asn Ser Asp Ile Lys Glu Arg Phe Thr Asn Tyr Val Leu Leu Leu Ile
        195                 200                 205

Val Cys Leu Arg Asn Met Glu Gln Phe Ser Trp Asn Pro Xaa His Leu
    210                 215                 220

Trp Val Leu Phe Pro Asp Val Cys Met Val Ile Ala Ser Glu Ile Ala
225                 230                 235                 240

Val Asp Ile Val Lys His Ala Phe Ile Thr Lys Phe Asn Asp Ile Thr
                245                 250                 255

Ala Asp Val Tyr Ser Glu Tyr Arg Ala Ser Leu Ala Phe Asp Leu Val
            260                 265                 270

Ser Ser Arg Gln Lys Asn Ala Tyr Thr Asp Tyr Ser Asp Ser Val Ala
        275                 280                 285

Arg Arg Met Gly Phe Ile Pro Leu Pro Leu Ala Val Leu Leu Ile Arg
    290                 295                 300

Val Val Thr Ser Ser Ile Lys Val Gln Gly Ile Leu Ser Tyr Ala Cys
305                 310                 315                 320

Val Ile Leu Phe Tyr Phe Gly Leu Ile Ser Leu Lys Val Leu Asn Ser
                325                 330                 335

Ile Val Leu Leu Gly Lys Ser Cys Gln Tyr Val Lys Glu Ala Lys Met
            340                 345                 350

Glu Glu Lys Leu Ser Asn Pro Pro Ala Thr Cys Thr Pro Gly Lys Pro
        355                 360                 365

Ser Ser Lys Ser Gln Asn Lys Cys Lys Pro Ser Gln Gly Leu Ser Thr
    370                 375                 380

Glu Glu Asn Leu Ser Ala Ser Ile Thr Lys Gln Pro Ile His Gln Lys
385                 390                 395                 400

Glu Asn Ile Ile Pro Leu Leu Val Thr Ser Asn Ser Asp Gln Phe Leu
                405                 410                 415

Thr Thr Pro Asp Gly Asp Glu Lys Asp Ile Thr Gln Asp Asn Ser Glu
            420                 425                 430

Leu Lys His Arg Ser Ser Lys Lys Asp Leu Leu Glu Ile Asp Arg Phe
        435                 440                 445

Thr Ile Cys Gly Asn Arg Ile Asp 
    450                 455



<210> 1801
<211> 356
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (344)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1801
Met Phe His Gly Arg Glu Val Lys Pro Val Gly Pro Asp Leu Glu Leu
  1               5                  10                  15

Ser Glu Ala Glu Asn Gly Val Glu Glu Lys Lys Lys Ala Cys Arg Ser
             20                  25                  30

Pro Thr Ala Gln Ser Pro Thr Pro Ser Val Glu Ala Asp Ser Pro Asp
         35                  40                  45

Gln Lys Lys Ile Ile Ser Leu Trp Ser Lys Ser Ser Phe Asp Gly Ala
     50                  55                  60

Ser Leu Ala Ser Asp Lys Asn Asp Cys Lys Thr Glu Ser Lys Asn Asp
 65                  70                  75                  80

Pro Lys Thr Glu Arg Lys Lys Ser Ser Ser Ser Ser Gln Tyr Lys Ala
                 85                  90                  95

Asn Met His Phe His Lys Leu Xaa Leu Ser Val Pro Thr Glu Glu Pro
            100                 105                 110

Leu Lys Gln Ser Phe Thr Cys Ala Leu Gln Lys Glu Ile Leu Tyr Gln
        115                 120                 125

Gly Lys Leu Phe Val Ser Glu Asn Trp Ile Cys Phe His Ser Lys Val
    130                 135                 140

Phe Gly Lys Asp Thr Lys Ile Ser Ile Pro Ala Phe Ser Val Thr Leu
145                 150                 155                 160

Ile Lys Lys Thr Lys Thr Ala Leu Leu Val Pro Asn Ala Leu Ile Ile
                165                 170                 175

Ala Thr Val Thr Asp Arg Tyr Ile Phe Val Ser Leu Leu Ser Arg Asp
            180                 185                 190

Ser Thr Tyr Lys Leu Leu Lys Ser Val Cys Gly His Leu Glu Asn Thr
        195                 200                 205

Ser Val Gly Asn Ser Pro Asn Pro Ser Ser Ala Glu Asn Ser Phe Arg
    210                 215                 220

Ala Asp Arg Pro Ser Ser Leu Pro Leu Asp Phe Asn Asp Glu Phe Ser
225                 230                 235                 240

Asp Leu Asp Gly Val Val Gln Gln Arg Arg Gln Asp Met Glu Gly Tyr
                245                 250                 255

Ser Ser Ser Gly Ser Gln Thr Pro Glu Ser Glu Asn Ser Arg Asp Phe
            260                 265                 270

His Ala Thr Glu Ser Gln Thr Val Leu Asn Val Ser Lys Gly Glu Ala
        275                 280                 285

Lys Pro Thr Arg Ala Asp Ala His Val Asn Arg Val Pro Glu Gly Lys
    290                 295                 300

Ala Lys Ser Leu Pro Val Gln Gly Leu Ser Glu Thr Val Gly Ile Leu
305                 310                 315                 320

His Lys Val Lys Ser Gln Lys Cys Pro Met Leu His His Ile Leu Ile
                325                 330                 335

Phe Tyr Ala Ile Val Val Cys Xaa Thr Asn His Leu Asp Leu Leu His
            340                 345                 350

Glu Ile Gln Asn 
        355



<210> 1802
<211> 262
<212> PRT
<213> Homo sapiens

<400> 1802
Met Trp Leu Ser Phe Leu Lys His Lys Leu Pro Leu Ser Leu Tyr Lys
  1               5                  10                  15

Lys Val Leu Leu Ile Val His Asp Ala Ile Leu Pro Gln Leu Ala Gln
             20                  25                  30

Pro Thr Leu Met Ile Asp Phe Leu Thr Arg Ala Cys Asp Leu Gly Gly
         35                  40                  45

Ala Leu Ser Leu Leu Ala Leu Asn Gly Leu Phe Ile Leu Ile His Lys
     50                  55                  60

His Asn Leu Glu Tyr Pro Asp Phe Tyr Arg Lys Leu Tyr Gly Leu Leu
 65                  70                  75                  80

Asp Pro Ser Val Phe His Val Lys Tyr Arg Ala Arg Phe Phe His Leu
                 85                  90                  95

Ala Asp Leu Phe Leu Ser Ser Ser His Leu Pro Ala Tyr Leu Val Ala
            100                 105                 110

Ala Phe Ala Lys Arg Leu Ala Arg Leu Ala Leu Thr Ala Pro Pro Glu
        115                 120                 125

Ala Leu Leu Met Val Leu Pro Phe Ile Cys Asn Leu Leu Arg Arg His
    130                 135                 140

Pro Ala Cys Arg Val Leu Val His Arg Pro His Gly Pro Glu Leu Asp
145                 150                 155                 160

Ala Asp Pro Tyr Asp Pro Gly Glu Glu Asp Pro Ala Gln Ser Arg Ala
                165                 170                 175

Leu Glu Ser Ser Leu Trp Glu Leu Gln Ala Leu Gln Arg His Tyr His
            180                 185                 190

Pro Glu Val Ser Lys Ala Ala Ser Val Ile Asn Gln Ala Leu Ser Met
        195                 200                 205

Pro Glu Val Ser Ile Ala Pro Leu Leu Glu Leu Thr Ala Tyr Glu Ile
    210                 215                 220

Phe Glu Arg Asp Leu Lys Lys Lys Gly Pro Glu Pro Val Pro Leu Glu
225                 230                 235                 240

Phe Ile Pro Ala Gln Gly Leu Leu Gly Arg Pro Gly Glu Leu Cys Ala
                245                 250                 255

Gln His Phe Thr Leu Ser 
            260



<210> 1803
<211> 130
<212> PRT
<213> Homo sapiens

<400> 1803
Met Ser Ser Thr Trp Val Thr Asn His Ser Glu Ile Leu Asn Thr Tyr
  1               5                  10                  15

Pro Leu Gly Ala Gly Gly Gly Asn Asp Val Gln Tyr Leu Lys Gln Asn
             20                  25                  30

Leu Thr Trp Thr Glu Arg Leu Tyr Phe Pro Leu Leu His Glu Ser Leu
         35                  40                  45

Ile Ile Leu Gly Gly Leu Leu Cys Ile Pro Pro Phe Leu Leu Ser Pro
     50                  55                  60

Pro Leu Pro Phe Val Phe Ser Lys Glu Ser Glu Leu Arg Phe Pro Cys
 65                  70                  75                  80

Ser Pro Ala Thr Leu Ile Ser Lys Thr Cys Leu Cys Val Arg Phe Phe
                 85                  90                  95

Thr Gly Asn Met Thr Phe Cys Phe Cys Ile Gly Phe Thr Val Ile Gln
            100                 105                 110

Phe Ser Ser Leu Ile Ser Ser Lys Thr Lys Ser Glu Cys Thr Arg Phe
        115                 120                 125

Phe Arg 
    130



<210> 1804
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1804
Met Phe Xaa Cys Ala Lys Leu Ala Cys Thr Pro Ser Leu Ile Arg Ala
  1               5                  10                  15

Gly Ser Arg Val Ala Tyr Arg Pro Ile Ser Ala Ser Val Leu Ser Arg
             20                  25                  30

Pro Glu Ala Ser Arg Thr Gly Glu Gly Ser Thr Val Phe Asn Gly Ala
         35                  40                  45

Gln Asn Gly Val Ser Gln Leu Ile Gln Arg Glu Phe Gln Thr Ser Ala
     50                  55                  60

Ile Ser Arg Asp Ile Asp Thr Ala Ala Lys Phe Ile Gly Ala Gly Ala
 65                  70                  75                  80

Ala Thr Val Gly Val Ala Gly Ser Gly Ala Gly Ile Gly Thr Val Phe
                 85                  90                  95

Gly Ser Leu Ile Ile Gly Tyr Ala Arg Val Ile Ile Ser Ile Pro Lys
            100                 105                 110






<210> 1805
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (44)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1805
Met His His Tyr Asn Ala Gly Val Lys Gln Ser Ala Leu Leu Gly Leu
  1               5                  10                  15

Lys Asp Leu Leu Ser Gln Tyr Pro Phe Ile Ile Asp Ala His Leu Ser
             20                  25                  30

Asn Ile Leu Ser Glu Val Thr Ala Val Phe Thr Xaa Lys Asp Ala Asn
         35                  40                  45

Val Arg Leu Ala Ala Val Gln Leu Leu Gln Phe Leu Ala Pro Lys Ile
     50                  55                  60

Arg Ala Glu Gln Ile Ser Pro Xaa Phe Pro Leu Val Ser Gly Gly Gly
 65                  70                  75                  80

Leu Ser Gly Val Asp Glu Arg Leu Ala Ser Thr Glu Asn Leu Lys Gly
                 85                  90                  95

Phe Ile Glu Ile Ile Ile Pro Leu Leu Ile Glu Cys Trp Val Glu Ala
            100                 105                 110

Val Pro Pro Gln Leu Ala Thr Pro Xaa Gly Asn Gly Ile Glu Arg Glu
        115                 120                 125

Pro Leu Gln Xaa Met Gln Xaa Xaa Leu Asn Ile Ile Ser Leu Leu Trp
    130                 135                 140

Lys Leu Ser Asn Thr Gly 
145                 150



<210> 1806
<211> 427
<212> PRT
<213> Homo sapiens

<400> 1806
Met Gly Leu Phe Pro Pro Trp Val Pro Val Pro Pro Ser Val Ser Gln
  1               5                  10                  15

Glu Arg Asp Leu Ile Ala Glu Phe Ala Gln Val Thr Asn Trp Ser Ser
             20                  25                  30

Cys Cys Leu Arg Val Phe Ala Trp His Pro His Thr Asn Lys Phe Ala
         35                  40                  45

Val Ala Leu Leu Asp Asp Ser Val Arg Val Tyr Asn Ala Ser Ser Thr
     50                  55                  60

Ile Val Pro Ser Leu Lys His Arg Leu Gln Arg Asn Val Ala Ser Leu
 65                  70                  75                  80

Ala Trp Lys Pro Leu Ser Ala Ser Val Leu Ala Val Ala Cys Gln Ser
                 85                  90                  95

Cys Ile Leu Ile Trp Thr Leu Asp Pro Thr Ser Leu Ser Thr Arg Pro
            100                 105                 110

Ser Ser Gly Cys Ala Gln Val Leu Ser His Pro Gly His Thr Pro Val
        115                 120                 125

Thr Ser Leu Ala Trp Ala Pro Ser Gly Gly Arg Leu Leu Ser Ala Ser
    130                 135                 140

Pro Val Asp Ala Ala Ile Arg Val Trp Asp Val Ser Thr Glu Thr Cys
145                 150                 155                 160

Val Pro Leu Pro Trp Phe Arg Gly Gly Gly Val Thr Asn Leu Leu Trp
                165                 170                 175

Ser Pro Asp Gly Ser Lys Ile Leu Ala Thr Thr Pro Ser Ala Val Phe
            180                 185                 190

Arg Val Trp Glu Ala Gln Met Trp Thr Cys Glu Arg Trp Pro Thr Leu
        195                 200                 205

Ser Gly Arg Cys Gln Thr Gly Cys Trp Ser Pro Asp Gly Ser Arg Leu
    210                 215                 220

Leu Phe Thr Val Leu Gly Glu Pro Leu Ile Tyr Ser Leu Ser Phe Pro
225                 230                 235                 240

Glu Arg Cys Gly Glu Gly Lys Gly Cys Val Gly Gly Ala Lys Ser Ala
                245                 250                 255

Thr Ile Val Ala Asp Leu Ser Glu Thr Thr Ile Gln Thr Pro Asp Gly
            260                 265                 270

Glu Glu Arg Leu Gly Gly Glu Ala His Ser Met Val Trp Asp Pro Ser
        275                 280                 285

Gly Glu Arg Leu Ala Val Leu Met Lys Gly Lys Pro Arg Val Gln Asp
    290                 295                 300

Gly Lys Pro Val Ile Leu Leu Phe Arg Thr Arg Asn Ser Pro Val Phe
305                 310                 315                 320

Glu Leu Leu Pro Cys Gly Ile Ile Gln Gly Glu Pro Gly Ala Gln Pro
                325                 330                 335

Gln Leu Ile Thr Phe His Pro Ser Phe Asn Lys Gly Ala Leu Leu Ser
            340                 345                 350

Val Gly Trp Ser Thr Gly Arg Ile Ala His Ile Pro Leu Tyr Phe Val
        355                 360                 365

Asn Ala Gln Phe Pro Arg Phe Ser Pro Val Leu Gly Arg Ala Gln Glu
    370                 375                 380

Pro Pro Ala Gly Gly Gly Gly Ser Ile His Asp Leu Pro Leu Phe Thr
385                 390                 395                 400

Glu Thr Ser Pro Thr Ser Ala Pro Trp Asp Pro Leu Pro Gly Pro Pro
                405                 410                 415

Pro Val Leu Pro His Ser Pro His Ser His Leu 
            420                 425



<210> 1807
<211> 164
<212> PRT
<213> Homo sapiens

<400> 1807
Met Ala Lys Ala Ala Arg Val Leu Thr Pro Gln Asp His Ser Pro Ala
  1               5                  10                  15

Leu Ser Ser Gly Gly Thr Ala Leu Gln Gly Val Leu Ala Val Gly Pro
             20                  25                  30

Ala Asn Phe Arg Gln Asn Arg Glu Ala Gln Arg Leu Gln Ile Pro Ser
         35                  40                  45

Cys Lys Trp Pro Gly Ile Leu Ser Leu Pro Ser Leu Ala Ser Gly Val
     50                  55                  60

Ile Leu Thr Ser Leu Ala Ser Pro Ile Pro Ser Thr Pro His Leu Ser
 65                  70                  75                  80

Ser Cys Leu Leu Leu Leu Gly Thr Pro Lys Thr Leu Leu Val Arg Arg
                 85                  90                  95

Lys Met Glu Gly Lys Phe Cys Arg Ser Phe Pro Asn Pro Gln Glu Trp
            100                 105                 110

Thr Arg Ser Gln Leu Arg Lys Lys Gly Leu Thr Trp Leu Ala Trp Leu
        115                 120                 125

Leu Arg Arg Pro Leu Phe Phe Ser Thr Ser Ala His Pro Cys Met Ser
    130                 135                 140

Ser Gln Thr Phe Ala Leu Lys Leu Gln Glu Thr Thr Ser Thr Gln Gly
145                 150                 155                 160

Leu Gly Phe Lys 




<210> 1808
<211> 116
<212> PRT
<213> Homo sapiens

<400> 1808
Met Ala Gly Ile Glu Leu Glu Arg Cys Gln Gln Gln Ala Asn Glu Val
  1               5                  10                  15

Thr Glu Ile Met Arg Asn Asn Phe Gly Lys Val Leu Glu Arg Gly Val
             20                  25                  30

Lys Leu Ala Glu Leu Gln Gln Arg Ser Asp Gln Leu Leu Asp Met Ser
         35                  40                  45

Ser Thr Phe Asn Lys Thr Thr Gln Asn Leu Ala Gln Lys Lys Cys Trp
     50                  55                  60

Glu Asn Ile Arg Tyr Arg Ile Cys Val Gly Leu Val Val Val Gly Val
 65                  70                  75                  80

Leu Leu Ile Ile Leu Ile Val Leu Leu Val Val Phe Leu Pro Gln Ser
                 85                  90                  95

Ser Asp Ser Ser Ser Ala Pro Arg Thr Gln Asp Ala Gly Ile Ala Ser
            100                 105                 110

Gly Pro Gly Asn 
        115



<210> 1809
<211> 195
<212> PRT
<213> Homo sapiens

<400> 1809
Met Ser Val Leu Ser Val Ser Ser Trp Thr Leu Pro His Ser Arg Pro
  1               5                  10                  15

Gly Lys Ser Thr Ser His Gln Pro Thr Pro Leu Lys Ser Trp Pro Gly
             20                  25                  30

Ser Pro Ala Arg Arg Thr Leu Thr Thr Cys Gln Thr Ser Gly Arg Arg
         35                  40                  45

Ser Ala Ala Val Arg Tyr Glu Ser Gln Leu Phe Gly Trp Leu Leu Ile
     50                  55                  60

Gly Val Val Ala Ile Leu Val Phe Leu Thr Lys Cys Leu Lys His Tyr
 65                  70                  75                  80

Cys Ser Pro Leu Ser Tyr Arg Gln Glu Ala Tyr Trp Ala Gln Tyr Arg
                 85                  90                  95

Ala Asn Glu Asp Gln Leu Phe Gln Arg Thr Ala Glu Val His Ser Arg
            100                 105                 110

Val Leu Ala Ala Asn Asn Val Arg Arg Phe Phe Gly Phe Val Ala Leu
        115                 120                 125

Asn Lys Asp Asp Glu Glu Leu Ile Ala Asn Phe Pro Val Glu Gly Thr
    130                 135                 140

Gln Pro Arg Pro Gln Trp Asn Ala Ile Thr Gly Val Tyr Leu Tyr Arg
145                 150                 155                 160

Glu Asn Gln Gly Leu Pro Leu Tyr Ser Arg Leu His Lys Trp Ala Gln
                165                 170                 175

Gly Leu Ala Gly Asn Gly Ala Ala Pro Asp Asn Val Glu Met Ala Leu
            180                 185                 190

Leu Pro Ser 
        195



<210> 1810
<211> 161
<212> PRT
<213> Homo sapiens

<400> 1810
Met Ser His Glu Ser Pro Gly Ile Glu Trp Leu Cys Leu Glu Asn Ala
  1               5                  10                  15

Pro Cys Tyr Asp Asn Val Pro Gln Gly Ile Phe Ala Pro Glu Phe Phe
             20                  25                  30

Phe Lys Val Leu Val Ser Asn Arg Gly Val Asp Thr Ser Thr Tyr Cys
         35                  40                  45

Asn Tyr Gln Leu Thr Phe Leu Leu His Ile His Gly Leu Pro Leu Ser
     50                  55                  60

Pro Lys Arg Ala Leu Phe Ile Ile Met Val Ser Ala Ser Val Phe Val
 65                  70                  75                  80

Gly Leu Val Ile Phe Tyr Ile Ala Phe Cys Leu Leu Trp Pro Leu Val
                 85                  90                  95

Val Lys Gly Cys Thr Met Ile Arg Trp Lys Ile Asn Asn Leu Ile Ala
            100                 105                 110

Ser Glu Ser Tyr Tyr Thr Tyr Ala Ser Ile Ser Gly Ile Ser Ser Met
        115                 120                 125

Pro Ser Leu Arg His Ser Arg Met Gly Ser Met Phe Ser Ser Arg Met
    130                 135                 140

Thr Glu Asp Arg Ala Glu Pro Lys Glu Ala Val Glu Arg Gln Leu Met
145                 150                 155                 160

Thr 




<210> 1811
<211> 175
<212> PRT
<213> Homo sapiens

<400> 1811
Met Gly Ile Gln Leu Ile Val Gln Asp Lys Glu Ser Val Phe Ser Pro
  1               5                  10                  15

Arg Arg Tyr Phe Asn Ile Asp Pro Asn Ala Thr Gln Ala Ser Gly Asn
             20                  25                  30

Cys Gly Thr Arg Lys Ser Asn Leu Leu Leu Asn Phe Gln Gly Gly Phe
         35                  40                  45

Val Asn Leu Thr Phe Thr Lys Asp Glu Glu Ser Tyr Tyr Ile Ser Glu
     50                  55                  60

Val Gly Ala Tyr Leu Thr Val Ser Asp Pro Glu Thr Val Tyr Gln Gly
 65                  70                  75                  80

Ile Lys His Ala Val Val Met Phe Gln Thr Ala Val Gly His Ser Phe
                 85                  90                  95

Lys Cys Val Ser Glu Gln Ser Leu Gln Leu Ser Ala His Leu Gln Val
            100                 105                 110

Lys Thr Thr Asp Val Gln Leu Gln Ala Phe Asp Phe Glu Asp Asp His
        115                 120                 125

Phe Gly Asn Val Asp Glu Cys Ser Ser Asp Tyr Thr Ile Val Leu Pro
    130                 135                 140

Val Ile Gly Ala Ile Val Val Gly Leu Cys Leu Met Gly Met Gly Val
145                 150                 155                 160

Tyr Lys Ile Arg Leu Arg Cys Gln Ser Ser Gly Tyr Gln Arg Ile 
                165                 170                 175



<210> 1812
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1812
Met Cys Ser Thr Thr Gly Val Ser Ala Leu Pro Lys Ser Lys Phe His
  1               5                  10                  15

Leu Ser Ala Lys Cys Arg Gly Ile Cys Phe Leu Leu Ser Xaa His Arg
             20                  25                  30

Ile Val Gly His Leu Phe Ala Gly Xaa Leu Arg Asp Phe Leu Ala Ile
         35                  40                  45

Tyr Leu Gln Ala Phe Phe Pro Ser Pro Lys Phe Leu Gly Trp Leu Cys
     50                  55                  60

Leu Leu Lys Glu Pro Val Phe Thr Lys Leu His Ser Gly Ala Ser Val
 65                  70                  75                  80

Arg Cys Leu Arg Ser Tyr Cys Arg Pro Phe Arg Thr Pro Ser Gln Glu
                 85                  90                  95

Arg Thr Leu Gln Pro Leu Ala Arg Asp Ser Thr Phe Phe Leu Ile Leu
            100                 105                 110

Phe Leu Thr Leu Leu Leu Leu Leu Leu Pro Thr Asn Ser Ile Ser Phe
        115                 120                 125

Phe Phe Leu Phe Leu Ser Phe Ser Tyr Ser Ser Phe Pro Pro Ser Leu
    130                 135                 140

Ser Cys 
145



<210> 1813
<211> 258
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (37)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1813
Met Pro Val Glu Lys Asn Ile Thr Leu Glu Arg Pro Ser Asn Val Asn
  1               5                  10                  15

Leu Thr Cys Gln Phe Xaa Thr Ser Gly Asp Leu Asn Ala Val Asn Val
             20                  25                  30

Thr Trp Lys Lys Xaa Gly Glu Gln Leu Glu Asn Asn Tyr Leu Val Ser
         35                  40                  45

Ala Thr Gly Ser Thr Leu Tyr Thr Gln Tyr Arg Phe Thr Ile Ile Asn
     50                  55                  60

Ser Lys Gln Met Gly Ser Tyr Ser Cys Phe Phe Arg Glu Glu Lys Glu
 65                  70                  75                  80

Gln Arg Gly Thr Phe Asn Phe Lys Val Pro Glu Leu His Gly Lys Asn
                 85                  90                  95

Lys Pro Leu Ile Ser Tyr Val Gly Asp Ser Thr Val Leu Thr Cys Lys
            100                 105                 110

Cys Gln Asn Cys Phe Pro Leu Asn Trp Thr Trp Tyr Ser Ser Asn Gly
        115                 120                 125

Ser Val Lys Val Pro Val Gly Val Gln Met Asn Lys Tyr Val Ile Asn
    130                 135                 140

Gly Thr Tyr Ala Asn Glu Thr Lys Leu Lys Ile Thr Gln Leu Leu Glu
145                 150                 155                 160

Glu Asp Gly Glu Ser Tyr Trp Cys Arg Ala Leu Phe Gln Leu Gly Glu
                165                 170                 175

Ser Glu Glu His Ile Glu Leu Val Val Leu Ser Tyr Leu Val Pro Leu
            180                 185                 190

Lys Pro Phe Leu Val Ile Val Ala Glu Val Ile Leu Leu Val Ala Thr
        195                 200                 205

Ile Leu Leu Cys Glu Lys Tyr Thr Gln Lys Lys Lys Lys His Ser Asp
    210                 215                 220

Glu Gly Lys Glu Phe Glu Gln Ile Glu Gln Leu Lys Ser Asp Asp Ser
225                 230                 235                 240

Asn Gly Ile Glu Asn Asn Val Pro Arg His Arg Lys Asn Glu Ser Leu
                245                 250                 255

Gly Gln 




<210> 1814
<211> 214
<212> PRT
<213> Homo sapiens

<400> 1814
Met Leu Pro Val Pro Trp Arg Gly Thr Gln His Arg Lys Ala Thr Tyr
  1               5                  10                  15

Ser Ala Trp Met Gly Gly Glu Ala Glu Gly Leu Thr Gly Gly His Gln
             20                  25                  30

Ala Ser Pro Gln Pro Gly Lys Trp Gly Gly Gly Ala Glu Thr His Ala
         35                  40                  45

Ser Gln Leu Ser Thr Gly Asn Val Ser Pro Val Ser Ile Gly Gln Ser
     50                  55                  60

Gly Ala Ser Trp Ser Glu Gln Ser His Gln Val Pro Leu Pro Arg Ala
 65                  70                  75                  80

Leu His Ser Pro Pro Ser Cys Leu Gly Gly Gly Gly Trp Arg Ser Leu
                 85                  90                  95

Glu Arg Leu Asp Cys Cys His Pro Gly Cys Ser Arg Ser Ala Ile Ala
            100                 105                 110

Leu Ile Ser Asp Asn Leu Gln Glu Cys Ser Ser Asp Gly Ile Thr Trp
        115                 120                 125

Asn Ser Phe Leu Phe Leu Phe Leu Phe Leu Phe Leu Trp Gly Gly Ala
    130                 135                 140

Thr Lys Gln Thr Gln Ser Ile Leu Cys Gln Val Leu Gly Trp Thr Gly
145                 150                 155                 160

Gln Leu Cys Val Gly Val Val Phe Phe Ser Ile Phe Leu Phe Val Ser
                165                 170                 175

Cys Phe Leu Ile Met Phe Thr Ile Cys Leu Asn His Ser Val Phe Tyr
            180                 185                 190

Lys Asp Ser Thr Ser Ser Pro Leu Ser Ser Pro Leu Leu Arg Pro Leu
        195                 200                 205

Arg Leu Leu Gly Asp Ala 
    210



<210> 1815
<211> 147
<212> PRT
<213> Homo sapiens

<400> 1815
Met Thr Pro Gly Gly Leu Phe Leu Pro Tyr His Ser Leu Pro Gln Pro
  1               5                  10                  15

Asp Phe Leu Ala Ser Cys Pro Thr Arg His Leu Lys Leu Cys Gln Cys
             20                  25                  30

Pro Gly Ile Leu Ala Glu Asn Pro His Gln Phe Ser Pro Thr Phe Pro
         35                  40                  45

Pro Gly Lys Gly Ser Cys Gln His Gly Ala Leu Pro Gly Gln Val Ser
     50                  55                  60

Leu Lys Glu Ala Ala His Thr Glu Met Ser Leu Ser Gly Gln Asp Leu
 65                  70                  75                  80

Phe Pro Ser Pro Ala His Pro Pro Leu Gln Pro Phe Trp Leu Pro Phe
                 85                  90                  95

Ser Leu Cys Leu Ser Thr Pro Phe Leu Val Ala Asp Asn Glu Leu Arg
            100                 105                 110

Leu Pro Lys Gly Gln Ile Cys Pro Leu His Val Phe Val Leu Ala Asn
        115                 120                 125

Arg Val Val Leu Lys Leu Cys Ala Asn Ser Val Trp Glu His Ser Lys
    130                 135                 140

Gly Ile Thr 
145



<210> 1816
<211> 201
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1816
Met Val Leu Ser Asn Ser Asn Gln Leu Leu Leu Asn Ser Leu Thr Gln
  1               5                  10                  15

Ala Asp Xaa Gly Thr Tyr Thr Cys Arg Ala Ile Leu Xaa Arg Ile Gly
             20                  25                  30

Val Ala Xaa Arg Glu Val Pro Leu Tyr Val Asn Gly Pro Pro Ile Ile
         35                  40                  45

Ser Ser Glu Ala Val Gln Tyr Ala Val Arg Gly Asp Gly Gly Lys Val
     50                  55                  60

Glu Cys Phe Ile Gly Ser Thr Pro Pro Pro Asp Arg Ile Ala Trp Ala
 65                  70                  75                  80

Trp Lys Glu Asn Phe Leu Glu Val Gly Thr Leu Glu Arg Tyr Thr Val
                 85                  90                  95

Glu Arg Thr Asn Ser Gly Ser Gly Val Leu Ser Thr Leu Thr Ile Asn
            100                 105                 110

Asn Val Met Glu Ala Asp Phe Gln Thr His Tyr Asn Cys Thr Ala Trp
        115                 120                 125

Asn Ser Phe Gly Pro Gly Thr Ala Ile Ile Gln Leu Glu Glu Arg Glu
    130                 135                 140

Val Leu Pro Val Gly Ile Ile Ala Gly Ala Thr Ile Gly Ala Ser Ile
145                 150                 155                 160

Leu Leu Ile Phe Phe Phe Ile Ala Leu Val Phe Phe Leu Tyr Arg Arg
                165                 170                 175

Arg Lys Gly Ser Arg Lys Asp Val Thr Leu Arg Lys Leu Asp Ile Lys
            180                 185                 190

Val Glu Thr Val Asn Arg Glu Pro Leu 
        195                 200



<210> 1817
<211> 301
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (295)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1817
Met Ile Thr Ala Gly Leu Ile His Trp Ile Leu Asn Thr Leu Asn Ile
  1               5                  10                  15

Thr Val His Ile Arg Asp Val Cys Val Phe Leu Ala Pro Thr Phe Ser
             20                  25                  30

Gly Leu Thr Ser Ile Ser Thr Phe Leu Leu Thr Arg Glu Leu Trp Asn
         35                  40                  45

Gln Gly Ala Gly Leu Leu Ala Ala Cys Phe Ile Ala Ile Val Pro Gly
     50                  55                  60

Tyr Ile Ser Arg Ser Val Ala Gly Ser Phe Asp Asn Glu Gly Ile Ala
 65                  70                  75                  80

Ile Phe Ala Leu Gln Phe Thr Tyr Tyr Leu Trp Val Lys Ser Val Lys
                 85                  90                  95

Thr Gly Ser Val Phe Trp Thr Met Cys Cys Cys Leu Ser Tyr Phe Tyr
            100                 105                 110

Met Val Ser Ala Trp Gly Gly Tyr Val Phe Ile Ile Asn Leu Ile Pro
        115                 120                 125

Leu His Val Phe Val Leu Leu Leu Met Gln Arg Tyr Ser Lys Arg Val
    130                 135                 140

Tyr Ile Ala Tyr Ser Thr Phe Tyr Ile Val Gly Leu Ile Leu Ser Met
145                 150                 155                 160

Gln Ile Pro Phe Val Gly Phe Gln Pro Ile Arg Thr Ser Glu His Met
                165                 170                 175

Ala Ala Ala Gly Val Phe Ala Leu Leu Gln Ala Tyr Ala Phe Leu Gln
            180                 185                 190

Tyr Leu Arg Asp Arg Leu Thr Lys Gln Glu Phe Gln Thr Leu Phe Phe
        195                 200                 205

Leu Gly Val Ser Leu Ala Ala Gly Ala Val Phe Leu Ser Val Ile Tyr
    210                 215                 220

Leu Thr Tyr Thr Gly Tyr Ile Ala Pro Trp Ser Gly Arg Phe Tyr Ser
225                 230                 235                 240

Leu Trp Asp Thr Gly Tyr Ala Lys Ile His Ile Pro Ile Ile Ala Ser
                245                 250                 255

Val Ser Glu His Gln Pro Thr Thr Trp Val Ser Phe Phe Phe Asp Leu
            260                 265                 270

His Ile Leu Val Cys Thr Phe Pro Ala Gly Leu Trp Phe Cys Ile Lys
        275                 280                 285

Asn Ile Asn Asp Glu Arg Xaa Phe Gly Lys Arg Gly Phe 
    290                 295                 300



<210> 1818
<211> 379
<212> PRT
<213> Homo sapiens

<400> 1818
Met Lys Lys Ala Ala Ser Lys Gly Leu His Gln Ala Val Asn Gly Leu
  1               5                  10                  15

Gly Trp Tyr Tyr His Lys Phe Lys Lys Asn Tyr Ala Lys Ala Ala Lys
             20                  25                  30

Tyr Trp Leu Lys Ala Glu Glu Met Gly Asn Pro Asp Ala Ser Tyr Asn
         35                  40                  45

Leu Gly Val Leu His Leu Asp Gly Ile Phe Pro Gly Val Pro Gly Arg
     50                  55                  60

Asn Gln Thr Leu Ala Gly Glu Tyr Phe His Lys Ala Ala Gln Gly Gly
 65                  70                  75                  80

His Met Glu Gly Thr Leu Trp Cys Ser Leu Tyr Tyr Ile Thr Gly Asn
                 85                  90                  95

Leu Glu Thr Phe Pro Arg Asp Pro Glu Lys Ala Val Val Trp Ala Lys
            100                 105                 110

His Val Ala Glu Lys Asn Gly Tyr Leu Gly His Val Ile Arg Lys Gly
        115                 120                 125

Leu Asn Ala Tyr Leu Glu Gly Ser Trp His Glu Ala Leu Leu Tyr Tyr
    130                 135                 140

Val Leu Ala Ala Glu Thr Gly Ile Glu Val Ser Gln Thr Asn Leu Ala
145                 150                 155                 160

His Ile Cys Glu Glu Arg Pro Asp Leu Ala Arg Arg Tyr Leu Gly Val
                165                 170                 175

Asn Cys Val Trp Arg Tyr Tyr Asn Phe Ser Val Phe Gln Ile Asp Ala
            180                 185                 190

Pro Ser Phe Ala Tyr Leu Lys Met Gly Asp Leu Tyr Tyr Tyr Gly His
        195                 200                 205

Gln Asn Gln Ser Gln Asp Leu Glu Leu Ser Val Gln Met Tyr Ala Gln
    210                 215                 220

Ala Ala Leu Asp Gly Asp Ser Gln Gly Phe Phe Asn Leu Ala Leu Leu
225                 230                 235                 240

Ile Glu Glu Gly Thr Ile Ile Pro His His Ile Leu Asp Phe Leu Glu
                245                 250                 255

Ile Asp Ser Thr Leu His Ser Asn Asn Ile Ser Ile Leu Gln Glu Leu
            260                 265                 270

Tyr Glu Arg Cys Trp Ser His Ser Asn Glu Glu Ser Phe Ser Pro Cys
        275                 280                 285

Ser Leu Ala Trp Leu Tyr Leu His Leu Arg Leu Leu Trp Gly Ala Ile
    290                 295                 300

Leu His Ser Ala Leu Ile Tyr Phe Leu Gly Thr Phe Leu Leu Ser Ile
305                 310                 315                 320

Leu Ile Ala Trp Thr Val Gln Tyr Phe Gln Ser Val Ser Ala Ser Asp
                325                 330                 335

Pro Pro Pro Arg Pro Ser Gln Ala Ser Pro Asp Thr Ala Thr Ser Thr
            340                 345                 350

Ala Ser Pro Ala Val Thr Pro Ala Ala Asp Ala Ser Asp Gln Asp Gln
        355                 360                 365

Pro Thr Val Thr Asn Asn Pro Glu Pro Arg Gly 
    370                 375



<210> 1819
<211> 106
<212> PRT
<213> Homo sapiens

<400> 1819
Met Ala Ser Ser Asp Glu Asp Gly Thr Asn Gly Gly Ala Ser Glu Ala
  1               5                  10                  15

Gly Glu Asp Arg Glu Ala Pro Gly Lys Arg Arg Arg Leu Gly Phe Leu
             20                  25                  30

Ala Thr Ala Trp Leu Thr Phe Tyr Asp Ile Ala Met Thr Ala Gly Trp
         35                  40                  45

Leu Val Leu Ala Ile Ala Met Val Arg Phe Tyr Met Glu Lys Gly Thr
     50                  55                  60

His Arg Gly Leu Tyr Lys Ser Ile Gln Lys Thr Leu Lys Phe Phe Gln
 65                  70                  75                  80

Thr Phe Ala Leu Leu Glu Ile Val His Cys Leu Ile Gly Ile Val Pro
                 85                  90                  95

Thr Ser Val Asn Cys Glu Leu Gly Ser Lys 
            100                 105



<210> 1820
<211> 191
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1820
Met Val Asn Glu Asp Leu Leu Ser Asp Gly Thr Ser Glu Asn Glu Ser
  1               5                  10                  15

Gly Phe Trp Asp Ser Phe Lys Trp Gly Phe Thr Gly Gln Lys Thr Glu
             20                  25                  30

Glu Val Lys Gln Asp Lys Asp Asp Ile Ile Asn Ile Phe Ser Val Ala
         35                  40                  45

Ser Gly His Leu Tyr Glu Arg Phe Leu Arg Ile Met Met Leu Ser Val
     50                  55                  60

Leu Lys Asn Thr Lys Thr Xaa Val Lys Phe Trp Phe Leu Lys Asn Tyr
 65                  70                  75                  80

Leu Ser Pro Thr Phe Lys Glu Phe Ile Pro Tyr Met Ala Asn Glu Tyr
                 85                  90                  95

Asn Phe Gln Tyr Glu Leu Val Gln Tyr Lys Trp Pro Arg Trp Leu His
            100                 105                 110

Gln Gln Thr Glu Lys Gln Arg Ile Ile Trp Gly Tyr Lys Ile Leu Phe
        115                 120                 125

Leu Asp Val Leu Phe Pro Leu Val Val Asp Lys Phe Leu Phe Val Asp
    130                 135                 140

Ala Asp Gln Ile Val Arg Thr Asp Leu Lys Glu Leu Arg Asp Phe Asn
145                 150                 155                 160

Leu Asp Gly Ala Pro Tyr Gly Tyr Thr Pro Phe Cys Asp Ser Arg Glu
                165                 170                 175

Lys Trp Thr Val Gln Val Trp Lys Ser Gly Thr Gly Ala Ile Ile 
            180                 185                 190



<210> 1821
<211> 158
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1821
Met Lys Val Asp Ala Leu Leu Ser Ala Gln Pro Lys Gly Asp Pro Arg
  1               5                  10                  15

Ile Glu Tyr Gln Phe Phe Glu Asp Arg His Ser Ala Ile Lys Leu Arg
             20                  25                  30

Pro Lys Glu Gly Glu Thr Tyr Phe Asp Val Val Ala Val Val Asp Pro
         35                  40                  45

Val Thr Arg Glu Ala Gln Arg Leu Ala Pro Leu Leu Leu Val Leu Ala
     50                  55                  60

Gln Leu Ile Asn Met Asn Leu Arg Val Phe Met Asn Cys Gln Ser Lys
 65                  70                  75                  80

Leu Ser Asp Met Pro Leu Lys Ser Phe Tyr Arg Tyr Val Leu Glu Pro
                 85                  90                  95

Glu Ile Ser Phe Thr Ser Asp Asn Ser Phe Ala Lys Gly Pro Ile Ala
            100                 105                 110

Lys Phe Leu Asp Met Pro Gln Ser Xaa Leu Phe Thr Leu Asn Leu Asn
        115                 120                 125

Thr Pro Glu Ser Trp Met Val Glu Ser Val Arg Thr Pro Tyr Asp Leu
    130                 135                 140

Asp Asn Ile Tyr Leu Glu Arg Xaa Gly Gln Cys Xaa Gly Cys 
145                 150                 155



<210> 1822
<211> 170
<212> PRT
<213> Homo sapiens

<400> 1822
Met Thr Val Asn Gly Phe Ile Asn Thr Val Ile Thr Ser Leu Glu Arg
  1               5                  10                  15

Arg Tyr Asp Leu His Ser Tyr Gln Ser Gly Leu Ile Ala Ser Ser Tyr
             20                  25                  30

Asp Ile Ala Ala Cys Leu Cys Leu Thr Phe Val Ser Tyr Phe Gly Gly
         35                  40                  45

Ser Gly His Lys Pro Arg Trp Leu Gly Trp Gly Val Leu Leu Met Gly
     50                  55                  60

Thr Gly Ser Leu Val Phe Ala Leu Pro His Phe Thr Ala Gly Arg Tyr
 65                  70                  75                  80

Glu Val Glu Leu Asp Ala Gly Val Arg Thr Cys Pro Ala Asn Pro Gly
                 85                  90                  95

Ala Val Cys Ala Asp Ser Thr Ser Gly Leu Ser Arg Tyr Gln Leu Val
            100                 105                 110

Phe Met Leu Gly Gln Phe Leu His Gly Val Gly Ala Thr Pro Leu Tyr
        115                 120                 125

Thr Leu Gly Val Thr Tyr Leu Asp Glu Asn Val Lys Ser Ser Cys Ser
    130                 135                 140

Pro Val Tyr Ile Ala Ile Phe Tyr Thr Ala Ala Ile Leu Gly Pro Ala
145                 150                 155                 160

Ala Gly Tyr Leu Asn Trp Glu Val Pro Cys 
                165                 170



<210> 1823
<211> 128
<212> PRT
<213> Homo sapiens

<400> 1823
Met Leu Lys Leu Gly Ala Ser Val Asn Met Tyr Met Phe His Gly Gly
  1               5                  10                  15

Thr Asn Phe Gly Tyr Trp Asn Gly Ala Asp Lys Lys Gly Arg Phe Leu
             20                  25                  30

Pro Ile Thr Thr Ser Tyr Asp Tyr Asp Ala Pro Ile Ser Glu Ala Gly
         35                  40                  45

Asp Pro Thr Pro Lys Leu Phe Ala Leu Arg Asp Val Ile Ser Lys Phe
     50                  55                  60

Gln Glu Val Pro Leu Gly Pro Leu Pro Pro Pro Ser Pro Lys Met Met
 65                  70                  75                  80

Leu Gly Pro Val Thr Leu His Leu Val Gly His Leu Leu Ala Phe Leu
                 85                  90                  95

Asp Leu Leu Cys Pro Arg Gly Pro Ile His Ser Ile Leu Pro Met Thr
            100                 105                 110

Phe Glu Ala Val Asn Arg Thr Met Ala Ser Cys Cys Thr Glu Pro Ile
        115                 120                 125






<210> 1824
<211> 329
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (185)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1824
Met Lys Gly Met Lys Val Glu Val Leu Asn Ser Asp Ala Val Leu Pro
  1               5                  10                  15

Ser Arg Val Tyr Trp Ile Ala Ser Val Ile Gln Thr Ala Gly Tyr Arg
             20                  25                  30

Val Leu Leu Arg Tyr Glu Gly Phe Glu Asn Asp Ala Ser His Asp Phe
         35                  40                  45

Trp Cys Asn Trp Gly Thr Val Asp Val His Pro Ile Gly Trp Cys Ala
     50                  55                  60

Ile Asn Ser Lys Ile Leu Val Pro Pro Arg Thr Ile His Ala Lys Phe
 65                  70                  75                  80

Thr Asp Trp Lys Gly Tyr Leu Met Lys Arg Leu Val Gly Ser Arg Thr
                 85                  90                  95

Leu Pro Val Asp Phe His Ile Lys Met Val Glu Ser Met Lys Tyr Pro
            100                 105                 110

Phe Arg Gln Gly Met Arg Leu Glu Val Val Asp Lys Ser Gln Val Ser
        115                 120                 125

Arg Thr Arg Met Ala Val Val Asp Thr Val Ile Gly Gly Arg Leu Arg
    130                 135                 140

Leu Leu Tyr Glu Asp Gly Asp Ser Asp Asp Asp Phe Trp Cys His Met
145                 150                 155                 160

Trp Ser Pro Leu Ile His Pro Val Gly Trp Ser Arg Arg Val Gly His
                165                 170                 175

Gly Ile Lys Met Ser Glu Arg Arg Xaa Asp Met Ala His His Pro Thr
            180                 185                 190

Phe Arg Lys Ile Tyr Cys Asp Ala Val Pro Tyr Leu Phe Lys Lys Val
        195                 200                 205

Arg Ala Val Tyr Thr Glu Gly Gly Trp Phe Glu Glu Gly Met Xaa Leu
    210                 215                 220

Glu Ala Ile Asp Pro Leu Asn Leu Gly Asn Ile Cys Val Ala Thr Val
225                 230                 235                 240

Cys Lys Val Leu Leu Asp Gly Tyr Leu Met Ile Cys Val Asp Gly Gly
                245                 250                 255

Pro Ser Thr Asp Gly Leu Asp Trp Phe Cys Tyr His Ala Ser Ser His
            260                 265                 270

Ala Ile Phe Pro Ala Thr Phe Cys Gln Lys Asn Asp Ile Glu Leu Thr
        275                 280                 285

Pro Pro Lys Gly Tyr Glu Ala Gln Thr Phe Asn Trp Glu Asn Tyr Leu
    290                 295                 300

Glu Lys Thr Lys Ser Lys Ala Val His Arg Asp Ser Leu Thr Trp Ile
305                 310                 315                 320

Ala Gln Thr Met Ala Ser Arg Trp Ala 
                325



<210> 1825
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1825
Met Ala Ile Leu Leu Ser Tyr Cys Ser Ile Leu Cys Asn Tyr Lys Ala
  1               5                  10                  15

Ile Glu Met Pro Ser His Gln Thr Tyr Gly Gly Ser Trp Lys Phe Leu
             20                  25                  30

Thr Phe Ile Asp Leu Val Ile Gln Ala Val Phe Phe Gly Ile Cys Val
         35                  40                  45

Leu Thr Asp Leu Ser Ser Leu Leu Thr Arg Gly Ser Gly Asn Gln Glu
     50                  55                  60

Gln Glu Arg Gln Leu Lys Lys Leu Ile Ser Leu Arg Asp Trp Met Leu
 65                  70                  75                  80

Ala Val Leu Ala Phe Pro Val Gly Val Phe Val Val Ala Val Phe Trp
                 85                  90                  95

Asp His Tyr Ala Tyr Asp Arg Glu Met Ile Tyr Pro Lys Leu Leu Asp
            100                 105                 110

Asn Leu Ser Gln Gly Ala Glu Ser Arg Met His Ser Lys Leu Lys Val
        115                 120                 125

Ser Trp His Ala Phe Gln Xaa Pro Leu Thr Phe 
    130                 135



<210> 1826
<211> 110
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1826
Met Glu Gly Ser Gly Asp His Gly Ile Lys Arg Lys Pro Arg Lys Arg
  1               5                  10                  15

Ser Gln Ala Lys Ile Arg Leu Arg Lys Ser Lys Arg Lys Ala Lys Lys
             20                  25                  30

Arg Arg Arg Asn Ser Arg Lys Gln Xaa Gln Val Asn Gln Gln Ile Trp
         35                  40                  45

Leu Asp Asn Ile Ala Xaa Leu Ser Val Xaa Leu Xaa Phe Met Leu Cys
     50                  55                  60

His Ser Arg Asp Phe Cys His Leu Ala Ala Thr Leu Lys Thr Val Leu
 65                  70                  75                  80

Leu Ser Ala Lys Val Leu Leu Leu Gln Ala Thr Leu Arg Glu Ser Gly
                 85                  90                  95

Asp Xaa Tyr Phe Ser Xaa Ser Phe Arg Lys Arg Gly Glu Ser 
            100                 105                 110



<210> 1827
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1827
Met Cys Glu Ile Met Asn His Met Thr Ala Leu Leu Ser Val Trp Phe
  1               5                  10                  15

Phe Ile Gly Val His Leu Tyr Pro Phe Met Ile Asn Lys Leu Val Tyr
             20                  25                  30

Ile Val Ile Thr Val Ile Ile Phe Ser Lys Met Phe Leu Lys Ile Ile
         35                  40                  45

Ile Val Ile Thr Ser Val Ile Ala Gln Arg Glu Leu Gly Ile Asp Phe
     50                  55                  60

Ile Gln Leu Thr Leu Tyr Val Ile Arg Val Phe Phe Ile Ser Ser Ser
 65                  70                  75                  80

Val Gly Ser Ser Ala Ser Ser Ser Ala Thr Arg Arg Glu Ser Leu Ser
                 85                  90                  95

Thr Ser Ser Asp Leu Tyr Lys Arg Ser Ser Ser Ser Leu Ala Pro Ile
            100                 105                 110

Gly Gln Pro Phe Tyr Asn Ser Leu Gly Phe Ser Ser Ser Pro Ser Pro
        115                 120                 125

Ile Gly Met Pro Leu Pro Ser Gln Thr Pro Gly His Ser Leu Thr Pro
    130                 135                 140

Pro Xaa Ser Leu Ser Ser His Gly Ser Ser Ser Ser Leu His Leu Gly
145                 150                 155                 160

Lys Lys Lys Pro Lys Pro Phe Leu Phe Val Cys Ile His Val Cys Val
                165                 170                 175

Phe Val Cys Val Phe Ile Ile Tyr Val Lys Tyr Leu Met Leu Val Lys
            180                 185                 190

Thr Cys Gln Ile Ala Phe Ala Phe Arg Tyr 
        195                 200



<210> 1828
<211> 291
<212> PRT
<213> Homo sapiens

<400> 1828
Met Thr Asn Asp Ser Glu Gly Lys Met Gly Phe Lys His Pro Lys Ile
  1               5                  10                  15

Met Gly Asn Phe Arg Gly His Ala Leu Pro Gly Thr Phe Phe Phe Ile
             20                  25                  30

Ile Gly Leu Trp Trp Cys Thr Lys Ser Ile Leu Lys Tyr Ile Cys Lys
         35                  40                  45

Lys Gln Lys Arg Thr Cys Tyr Leu Gly Ser Lys Thr Leu Phe Tyr Arg
     50                  55                  60

Leu Glu Ile Leu Glu Gly Ile Thr Ile Val Gly Met Ala Leu Thr Gly
 65                  70                  75                  80

Met Ala Gly Glu Gln Phe Ile Pro Gly Gly Pro His Leu Met Leu Tyr
                 85                  90                  95

Asp Tyr Lys Gln Gly His Trp Asn Gln Leu Leu Gly Trp His His Phe
            100                 105                 110

Thr Met Tyr Phe Phe Phe Gly Leu Leu Gly Val Ala Asp Ile Leu Cys
        115                 120                 125

Phe Thr Ile Ser Ser Leu Pro Val Ser Leu Thr Lys Leu Met Leu Ser
    130                 135                 140

Asn Ala Leu Phe Val Glu Ala Phe Ile Phe Tyr Asn His Thr His Gly
145                 150                 155                 160

Arg Glu Met Leu Asp Ile Phe Val His Gln Leu Leu Val Leu Val Val
                165                 170                 175

Phe Leu Thr Gly Leu Val Ala Phe Leu Glu Phe Leu Val Arg Asn Asn
            180                 185                 190

Val Leu Leu Glu Leu Leu Arg Ser Ser Leu Ile Leu Leu Gln Gly Ser
        195                 200                 205

Trp Phe Phe Gln Ile Gly Phe Val Leu Tyr Pro Pro Ser Gly Gly Pro
    210                 215                 220

Ala Trp Asp Leu Met Asp His Glu Asn Ile Leu Phe Leu Thr Ile Cys
225                 230                 235                 240

Phe Cys Trp His Tyr Ala Val Thr Ile Val Ile Val Gly Met Asn Tyr
                245                 250                 255

Ala Phe Ile Thr Trp Leu Val Lys Ser Arg Leu Lys Arg Leu Cys Ser
            260                 265                 270

Ser Glu Val Gly Leu Leu Lys Asn Ala Glu Arg Glu Gln Glu Ser Glu
        275                 280                 285

Glu Glu Met 
    290



<210> 1829
<211> 423
<212> PRT
<213> Homo sapiens

<400> 1829
Met Leu Asp Ser Gln Thr Tyr Tyr Ser Asn Phe Trp Cys Gly Ile Thr
  1               5                  10                  15

Pro Gln Gly Tyr Tyr Arg Arg Thr Ala Glu Tyr Phe Pro Thr Lys Asn
             20                  25                  30

Arg Gln Arg Arg Gly Cys Phe Arg Val Pro Met Val His Ser Thr Phe
         35                  40                  45

Leu Ala Ser Leu Arg Ala Glu Gly Ala Asp Gln Leu Ala Phe Tyr Pro
     50                  55                  60

Pro His Pro Asn Tyr Thr Trp Pro Phe Asp Asp Ile Ile Val Phe Ala
 65                  70                  75                  80

Tyr Ala Cys Gln Ala Ala Gly Val Ser Val His Val Cys Asn Glu His
                 85                  90                  95

Arg Tyr Gly Tyr Met Asn Val Pro Val Lys Ser His Gln Gly Leu Glu
            100                 105                 110

Asp Glu Arg Val Asn Phe Ile His Leu Ile Leu Glu Ala Leu Val Asp
        115                 120                 125

Gly Pro Arg Met Gln Ala Ser Ala His Val Thr Arg Pro Ser Lys Arg
    130                 135                 140

Pro Ser Lys Ile Gly Phe Asp Glu Val Phe Val Ile Ser Leu Ala Arg
145                 150                 155                 160

Arg Pro Asp Arg Arg Glu Arg Met Leu Ala Ser Leu Trp Glu Met Glu
                165                 170                 175

Ile Ser Gly Arg Val Val Asp Ala Val Asp Gly Trp Met Leu Asn Ser
            180                 185                 190

Ser Ala Ile Arg Asn Leu Gly Val Asp Leu Leu Pro Gly Tyr Gln Asp
        195                 200                 205

Pro Tyr Ser Gly Arg Thr Leu Thr Lys Gly Glu Val Gly Cys Phe Leu
    210                 215                 220

Ser His Tyr Ser Ile Trp Glu Glu Val Val Ala Arg Gly Leu Ala Arg
225                 230                 235                 240

Val Leu Val Phe Glu Asp Asp Val Arg Phe Glu Ser Asn Phe Arg Gly
                245                 250                 255

Arg Leu Glu Arg Leu Met Glu Asp Val Glu Ala Glu Lys Leu Ser Trp
            260                 265                 270

Asp Leu Ile Tyr Leu Gly Arg Lys Gln Val Asn Pro Glu Lys Glu Thr
        275                 280                 285

Ala Val Glu Gly Leu Pro Gly Leu Val Val Ala Gly Tyr Ser Tyr Trp
    290                 295                 300

Thr Leu Ala Tyr Ala Leu Arg Leu Ala Gly Ala Arg Lys Leu Leu Ala
305                 310                 315                 320

Ser Gln Pro Leu Arg Arg Met Leu Pro Val Asp Glu Phe Leu Pro Ile
                325                 330                 335

Met Phe Asp Gln His Pro Asn Glu Gln Tyr Lys Ala His Phe Trp Pro
            340                 345                 350

Arg Asp Leu Val Ala Phe Ser Ala Gln Pro Leu Leu Ala Ala Pro Thr
        355                 360                 365

His Tyr Ala Gly Asp Ala Glu Trp Leu Ser Asp Thr Glu Thr Ser Ser
    370                 375                 380

Pro Trp Asp Asp Asp Ser Gly Arg Leu Ile Ser Trp Ser Gly Ser Gln
385                 390                 395                 400

Lys Thr Leu Arg Thr Pro Pro Gly Pro Asp Trp Gln Gln Arg Ala Gln
                405                 410                 415

Pro Pro Thr Pro Ala Pro Arg 
            420



<210> 1830
<211> 112
<212> PRT
<213> Homo sapiens

<400> 1830
Met Gln Asp Thr Gly Ser Val Val Pro Leu His Trp Phe Gly Phe Gly
  1               5                  10                  15

Tyr Ala Ala Leu Val Ala Ser Gly Gly Ile Ile Gly Tyr Val Lys Ala
             20                  25                  30

Gly Ser Val Pro Ser Leu Ala Ala Gly Leu Leu Phe Gly Ser Leu Ala
         35                  40                  45

Gly Leu Gly Ala Tyr Gln Leu Ser Gln Asp Pro Arg Asn Val Trp Val
     50                  55                  60

Phe Leu Ala Thr Ser Gly Thr Leu Ala Gly Ile Met Gly Met Arg Phe
 65                  70                  75                  80

Tyr His Ser Gly Lys Phe Met Pro Ala Gly Leu Ile Ala Gly Ala Ser
                 85                  90                  95

Leu Leu Met Val Ala Lys Val Gly Val Ser Met Phe Asn Arg Pro His
            100                 105                 110






<210> 1831
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1831
Met Tyr Val Cys Val His Ile Tyr Ile Tyr Ile Phe Ile Ile Thr Ile
  1               5                  10                  15

Phe Val Lys Phe Ile Ser Ile Asn Gly Glu Leu Gly Lys Leu Arg Lys
             20                  25                  30

Phe Asp Arg Asn Leu Ser Ser Val Ile Val Leu His Asn Leu Phe Pro
         35                  40                  45

Phe Cys Phe Ala Asn Leu Ser Ser Val Met Val Leu His Asn Leu Phe
     50                  55                  60

Pro Phe Cys Phe Ala Leu Cys Leu Val Ser Leu Asn Ile Tyr Val Thr
 65                  70                  75                  80

Gly Tyr Ile Leu Val Ile Leu Leu Lys Ser Arg Gln Leu Met Ser Thr
                 85                  90                  95

Ile Phe Phe Thr Asn Trp Ile Thr Arg Glu Ile Ile Lys Glu Phe Cys
            100                 105                 110

Leu Tyr Ser Pro Xaa Pro 
        115



<210> 1832
<211> 274
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (203)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (224)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1832
Met Asp Pro Glu Thr Arg Gly Gln Glu Ile Ile Lys Val Thr Pro Leu
  1               5                  10                  15

Gln Gln Met Leu Ala Ser Cys Thr Gly Ala Ile Leu Thr Ser Val Ile
             20                  25                  30

Val Thr Pro Leu Asp Val Val Lys Ile Arg Leu Gln Ala Gln Asn Asn
         35                  40                  45

Pro Leu Pro Lys Gly Lys Cys Phe Val Tyr Ser Asn Gly Leu Met Asp
     50                  55                  60

His Leu Cys Val Cys Glu Glu Gly Gly Asn Lys Leu Trp Tyr Lys Lys
 65                  70                  75                  80

Pro Gly Asn Phe Gln Gly Thr Leu Asp Ala Phe Phe Lys Ile Ile Arg
                 85                  90                  95

Asn Glu Gly Ile Lys Ser Leu Trp Ser Gly Leu Pro Pro Thr Leu Val
            100                 105                 110

Met Ala Val Pro Ala Thr Val Ile Tyr Phe Thr Cys Tyr Asp Gln Leu
        115                 120                 125

Ser Ala Leu Leu Arg Ser Lys Leu Gly Glu Asn Glu Thr Cys Ile Pro
    130                 135                 140

Ile Val Ala Gly Ile Val Ala Arg Phe Gly Ala Val Thr Xaa Ile Ser
145                 150                 155                 160

Pro Leu Glu Leu Ile Arg Thr Lys Met Gln Ser Lys Lys Phe Ser Tyr
                165                 170                 175

Val Glu Leu His Arg Phe Val Ser Lys Lys Val Ser Glu Asp Gly Trp
            180                 185                 190

Ile Ser Leu Trp Xaa Gly Trp Ala Pro Thr Xaa Leu Arg Asp Val Pro
        195                 200                 205

Phe Ser Val Ser Met Pro Leu His Met Ser Thr Trp Ile Ile Met Xaa
    210                 215                 220

Asn Ile Val Ala Lys Asn Gly Phe Ser Gly Leu Phe Ser Gly Leu Ile
225                 230                 235                 240

Pro Arg Leu Ile Lys Ile Ala Pro Ala Cys Ala Ile Met Ile Ser Thr
                245                 250                 255

Tyr Glu Phe Gly Lys Ala Phe Phe Gln Lys Gln Asn Val Arg Arg Gln
            260                 265                 270

Gln Tyr 




<210> 1833
<211> 226
<212> PRT
<213> Homo sapiens

<400> 1833
Met Thr Val Gly Leu Ala Val Cys Ala Leu Ile Val Gly Leu Ala Leu
  1               5                  10                  15

Ala Met Phe Phe Ala Val Trp Glu Ser Ala Lys Trp Arg Pro Val Ala
             20                  25                  30

Trp Ala Gly Ser Ala Leu Val Thr Ile Leu Arg Gly Leu Pro Glu Ile
         35                  40                  45

Leu Val Val Leu Phe Ile Tyr Phe Gly Ser Ser Gln Leu Leu Leu Thr
     50                  55                  60

Leu Ser Asp Gly Phe Thr Ile Asn Leu Gly Phe Val Gln Ile Pro Val
 65                  70                  75                  80

Gln Met Asp Ile Glu Asn Phe Asp Val Ser Pro Phe Leu Cys Gly Val
                 85                  90                  95

Ile Ala Leu Ser Leu Leu Tyr Ala Ala Tyr Ala Ser Gln Thr Leu Arg
            100                 105                 110

Gly Ala Leu Lys Ala Val Pro Val Gly Gln Trp Glu Ser Gly Gln Ala
        115                 120                 125

Leu Gly Leu Ser Lys Ser Ala Ile Phe Phe Arg Leu Val Met Pro Gln
    130                 135                 140

Met Trp Arg His Ala Leu Pro Gly Leu Gly Asn Gln Trp Leu Val Leu
145                 150                 155                 160

Leu Lys Asp Thr Ala Leu Val Ser Leu Ile Ser Val Asn Asp Leu Met
                165                 170                 175

Leu Gln Thr Lys Ser Ile Ala Thr Arg Thr Gln Glu Pro Phe Thr Trp
            180                 185                 190

Tyr Ile Val Ala Ala Ala Ile Tyr Leu Val Ile Thr Leu Leu Ser Gln
        195                 200                 205

Tyr Ile Leu Lys Arg Ile Asp Leu Arg Ala Thr Arg Phe Glu Arg Arg
    210                 215                 220

Pro Ser 
225



<210> 1834
<211> 112
<212> PRT
<213> Homo sapiens

<400> 1834
Met Ala Thr Arg Arg Cys Thr Ser Thr Thr Thr Arg Arg Ala Ser Leu
  1               5                  10                  15

Cys Lys Val Ala Tyr Glu Glu Leu Leu Asp Asn Arg Lys Leu Glu Val
             20                  25                  30

Thr Gln Thr Thr Asp Pro Ser Arg Gln Leu Glu Gly Gly Asn Leu Ala
         35                  40                  45

Leu Ala Ile Leu Leu Pro Leu Gly Leu Val Ile Val Leu Gly Ser Gly
     50                  55                  60

Val Tyr Ile Tyr Tyr Thr Lys Leu Gln Gly Lys Ser Leu Phe Gly Phe
 65                  70                  75                  80

Ser Gly Ser His Ser Tyr Ser Pro Ile Thr Val Glu Ser Asp Phe Ser
                 85                  90                  95

Asn Pro Leu Tyr Glu Ala Gly Asp Thr Arg Glu Tyr Glu Val Ser Ile
            100                 105                 110






<210> 1835
<211> 408
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (368)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (372)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (375)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (383)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (393)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (397)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (403)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1835
Met Ala Glu Ala Glu Glu Asp Cys His Ser Asp Thr Val Arg Ala Asp
  1               5                  10                  15

Asp Asp Glu Glu Asn Glu Ser Pro Ala Glu Thr Asp Leu Gln Ala Gln
             20                  25                  30

Leu Gln Met Phe Arg Ala Gln Trp Met Phe Glu Leu Ala Pro Gly Val
         35                  40                  45

Ser Ser Ser Asn Leu Glu Asn Arg Pro Cys Arg Ala Ala Arg Gly Ser
     50                  55                  60

Leu Gln Lys Thr Ser Ala Asp Thr Lys Gly Lys Gln Glu Gln Ala Lys
 65                  70                  75                  80

Glu Glu Lys Ala Arg Glu Leu Phe Leu Lys Ala Val Glu Glu Glu Gln
                 85                  90                  95

Asn Gly Ala Leu Tyr Glu Ala Ile Lys Phe Tyr Arg Arg Ala Met Gln
            100                 105                 110

Leu Val Pro Asp Ile Glu Phe Lys Ile Thr Tyr Thr Arg Ser Pro Asp
        115                 120                 125

Gly Asp Gly Val Gly Asn Ser Tyr Ile Glu Asp Asn Asp Asp Asp Ser
    130                 135                 140

Lys Met Ala Asp Leu Leu Ser Tyr Phe Gln Gln Gln Leu Thr Phe Gln
145                 150                 155                 160

Glu Ser Val Leu Lys Leu Cys Gln Pro Glu Leu Glu Ser Ser Gln Ile
                165                 170                 175

His Ile Ser Val Leu Pro Met Glu Val Leu Met Tyr Ile Phe Arg Trp
            180                 185                 190

Val Val Ser Ser Asp Leu Asp Leu Arg Ser Leu Glu Gln Leu Ser Leu
        195                 200                 205

Val Cys Arg Gly Phe Tyr Ile Cys Ala Arg Asp Pro Glu Ile Trp Arg
    210                 215                 220

Leu Ala Cys Leu Lys Val Trp Gly Arg Ser Cys Ile Lys Leu Val Pro
225                 230                 235                 240

Tyr Thr Ser Trp Arg Glu Met Phe Leu Glu Arg Pro Arg Val Arg Phe
                245                 250                 255

Asp Gly Val Tyr Ile Ser Lys Thr Thr Tyr Ile Arg Gln Gly Glu Gln
            260                 265                 270

Ser Leu Asp Gly Phe Tyr Arg Ala Trp His Gln Val Glu Tyr Tyr Arg
        275                 280                 285

Tyr Ile Arg Phe Phe Pro Asp Gly His Val Met Met Leu Thr Thr Pro
    290                 295                 300

Glu Glu Pro Gln Ser Ile Val Pro Arg Leu Arg Thr Arg Asn Thr Arg
305                 310                 315                 320

Thr Asp Ala Ile Leu Leu Gly His Tyr Arg Leu Ser Gln Asp Thr Asp
                325                 330                 335

Asn Gln Thr Lys Val Phe Ala Val Ile Thr Lys Lys Lys Glu Glu Lys
            340                 345                 350

Pro Leu Asp Tyr Lys Tyr Arg Tyr Phe Arg Arg Val Pro Val Gln Xaa
        355                 360                 365

Gly Arg Ser Xaa Val Phe Xaa Trp Gly Leu Gln Leu Cys Ser Xaa Trp
    370                 375                 380

Ser Pro Glu Val Ser Thr Asn Ser Xaa Trp Gly Thr Xaa Ile Ser Leu
385                 390                 395                 400

Phe Asn Xaa Tyr Phe Thr Gln Phe 
                405



<210> 1836
<211> 307
<212> PRT
<213> Homo sapiens

<400> 1836
Met Thr Lys Ala Gly Ser Lys Gly Gly Asn Leu Arg Asp Lys Leu Asp
  1               5                  10                  15

Gly Asn Glu Leu Asp Leu Ser Leu Ser Asp Leu Asn Glu Val Pro Val
             20                  25                  30

Lys Glu Leu Ala Ala Leu Pro Lys Ala Thr Ile Leu Asp Leu Ser Cys
         35                  40                  45

Asn Lys Leu Thr Thr Leu Pro Ser Asp Phe Cys Gly Leu Thr His Leu
     50                  55                  60

Val Lys Leu Asp Leu Ser Lys Asn Lys Leu Gln Gln Leu Pro Ala Asp
 65                  70                  75                  80

Phe Gly Arg Leu Val Asn Leu Gln His Leu Asp Leu Leu Asn Asn Lys
                 85                  90                  95

Leu Val Thr Leu Pro Val Ser Phe Ala Gln Leu Lys Asn Leu Lys Trp
            100                 105                 110

Leu Asp Leu Lys Asp Asn Pro Leu Asp Pro Val Leu Ala Lys Val Ala
        115                 120                 125

Gly Asp Cys Leu Asp Glu Lys Gln Cys Lys Gln Cys Ala Asn Lys Val
    130                 135                 140

Leu Gln His Met Lys Ala Val Gln Ala Asp Gln Glu Arg Glu Arg Gln
145                 150                 155                 160

Arg Arg Leu Glu Val Glu Arg Glu Ala Glu Lys Lys Arg Glu Ala Lys
                165                 170                 175

Gln Arg Ala Lys Glu Ala Gln Glu Arg Glu Leu Arg Lys Arg Glu Lys
            180                 185                 190

Ala Glu Glu Lys Glu Arg Arg Arg Lys Glu Tyr Asp Ala Leu Lys Ala
        195                 200                 205

Ala Lys Arg Glu Gln Glu Lys Lys Pro Lys Lys Glu Ala Asn Gln Ala
    210                 215                 220

Pro Lys Ser Lys Ser Gly Ser Arg Pro Arg Lys Pro Pro Pro Arg Lys
225                 230                 235                 240

His Thr Arg Ser Trp Ala Val Leu Lys Leu Leu Leu Leu Leu Leu Leu
                245                 250                 255

Phe Gly Val Ala Gly Gly Leu Val Ala Cys Arg Val Thr Glu Leu Gln
            260                 265                 270

Gln Gln Pro Leu Cys Thr Ser Val Asn Thr Ile Tyr Asp Asn Ala Val
        275                 280                 285

Gln Gly Leu Arg Arg His Glu Ile Leu Gln Trp Val Leu Gln Thr Asp
    290                 295                 300

Ser Gln Gln 
305



<210> 1837
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1837
Met Gly Pro Pro Gly Met Pro Gly Val Pro Gly Pro Met Gly Ile Pro
  1               5                  10                  15

Gly Glu Pro Gly Glu Glu Gly Arg Tyr Lys Gln Lys Phe Gln Ser Val
             20                  25                  30

Phe Thr Val Thr Arg Gln Thr His Gln Pro Pro Ala Pro Asn Ser Leu
         35                  40                  45

Ile Arg Phe Asn Ala Val Leu Asn Asn Pro Gln Glu Ile Met Thr Arg
     50                  55                  60

Ala Leu Ala Ser Ser Thr Ala Lys Ser Pro Ala Leu Ile Ile Cys Leu
 65                  70                  75                  80

Thr Ser Val Ala Tyr Ser Gln Xaa Cys Val Cys Cys Thr Ala Ala Ala
                 85                  90                  95

Ser Lys Xaa Ser Leu Leu Trp 
            100



<210> 1838
<211> 366
<212> PRT
<213> Homo sapiens

<400> 1838
Met Gly Leu Tyr Gln Lys Arg Asp Arg Thr Gln Gln Tyr Asp Asp Leu
  1               5                  10                  15

Ile Asp Glu Phe Met Lys Ala Ile Thr Asp Arg Tyr Gly Arg Asn Thr
             20                  25                  30

Leu Ile Gln Phe Glu Asp Phe Gly Asn His Asn Ala Phe Arg Phe Leu
         35                  40                  45

Arg Lys Tyr Arg Glu Lys Tyr Cys Thr Phe Asn Asp Asp Ile Gln Gly
     50                  55                  60

Thr Ala Ala Val Ala Leu Ala Gly Leu Leu Ala Ala Gln Lys Val Ile
 65                  70                  75                  80

Ser Lys Pro Ile Ser Glu His Lys Ile Leu Phe Leu Gly Ala Gly Glu
                 85                  90                  95

Ala Ala Leu Gly Ile Ala Asn Leu Ile Val Met Ser Met Val Glu Asn
            100                 105                 110

Gly Leu Ser Glu Gln Glu Ala Gln Lys Lys Ile Trp Met Phe Asp Lys
        115                 120                 125

Tyr Gly Leu Leu Val Lys Gly Arg Lys Ala Lys Ile Asp Ser Tyr Gln
    130                 135                 140

Glu Pro Phe Thr His Ser Ala Pro Glu Ser Ile Pro Asp Thr Phe Glu
145                 150                 155                 160

Asp Ala Val Asn Ile Leu Lys Pro Ser Thr Ile Ile Gly Val Ala Gly
                165                 170                 175

Ala Gly Arg Leu Phe Thr Pro Asp Val Ile Arg Ala Met Ala Ser Ile
            180                 185                 190

Asn Glu Arg Pro Val Ile Phe Ala Leu Ser Asn Pro Thr Ala Gln Ala
        195                 200                 205

Glu Cys Thr Ala Glu Glu Ala Tyr Thr Leu Thr Glu Gly Arg Cys Leu
    210                 215                 220

Phe Ala Ser Gly Ser Pro Phe Gly Pro Val Lys Leu Thr Asp Gly Arg
225                 230                 235                 240

Val Phe Thr Pro Gly Gln Gly Asn Asn Val Tyr Ile Phe Pro Gly Val
                245                 250                 255

Ala Leu Ala Val Ile Leu Cys Asn Thr Arg His Ile Ser Asp Ser Val
            260                 265                 270

Phe Leu Glu Ala Ala Lys Ala Leu Thr Ser Gln Leu Thr Asp Glu Glu
        275                 280                 285

Leu Ala Gln Gly Arg Leu Tyr Pro Pro Leu Ala Asn Ile Gln Glu Val
    290                 295                 300

Ser Ile Asn Ile Ala Ile Lys Val Thr Glu Tyr Leu Tyr Ala Asn Lys
305                 310                 315                 320

Met Ala Phe Arg Tyr Pro Glu Pro Glu Asp Lys Ala Lys Tyr Val Lys
                325                 330                 335

Glu Arg Thr Trp Arg Ser Glu Tyr Asp Ser Leu Leu Pro Asp Val Tyr
            340                 345                 350

Glu Trp Pro Glu Ser Ala Ser Ser Pro Pro Val Ile Thr Glu 
        355                 360                 365



<210> 1839
<211> 363
<212> PRT
<213> Homo sapiens

<400> 1839
Met Lys Arg Ser Leu Asn Glu Asn Ser Ala Arg Ser Thr Ala Gly Cys
  1               5                  10                  15

Leu Pro Val Pro Leu Phe Asn Gln Lys Lys Arg Asn Arg Gln Pro Leu
             20                  25                  30

Thr Ser Asn Pro Leu Lys Asp Asp Ser Gly Ile Ser Thr Pro Ser Asp
         35                  40                  45

Asn Tyr Asp Phe Pro Pro Leu Pro Thr Asp Trp Ala Trp Glu Ala Val
     50                  55                  60

Asn Pro Glu Leu Ala Pro Val Met Lys Thr Val Asp Thr Gly Gln Ile
 65                  70                  75                  80

Pro His Ser Val Ser Arg Pro Leu Arg Ser Gln Asp Ser Val Phe Asn
                 85                  90                  95

Ser Ile Gln Ser Asn Thr Gly Arg Ser Gln Gly Gly Trp Ser Tyr Arg
            100                 105                 110

Asp Gly Asn Lys Asn Thr Ser Leu Lys Thr Trp Asn Lys Asn Asp Phe
        115                 120                 125

Lys Pro Gln Cys Lys Arg Thr Asn Leu Val Ala Asn Asp Gly Lys Asn
    130                 135                 140

Ser Cys Pro Met Ser Ser Gly Ala Gln Gln Gln Lys Gln Leu Arg Thr
145                 150                 155                 160

Pro Glu Pro Pro Asn Leu Ser Arg Asn Lys Glu Thr Glu Leu Leu Arg
                165                 170                 175

Gln Thr His Ser Ser Lys Ile Ser Gly Cys Thr Met Arg Gly Leu Asp
            180                 185                 190

Lys Asn Ser Ala Leu Gln Thr Leu Lys Pro Asn Phe Gln Gln Asn Gln
        195                 200                 205

Tyr Lys Lys Gln Met Leu Asp Asp Ile Pro Glu Asp Asn Thr Leu Lys
    210                 215                 220

Glu Thr Ser Leu Tyr Gln Leu Gln Phe Lys Glu Lys Ala Ser Ser Leu
225                 230                 235                 240

Arg Ile Ile Ser Ala Val Ile Glu Ser Met Lys Tyr Trp Arg Glu His
                245                 250                 255

Ala Gln Lys Thr Val Leu Leu Phe Glu Val Leu Ala Val Leu Asp Ser
            260                 265                 270

Ala Val Thr Pro Gly Pro Tyr Tyr Ser Lys Thr Phe Leu Met Arg Asp
        275                 280                 285

Gly Lys Asn Thr Leu Pro Cys Val Phe Tyr Glu Ile Asp Arg Glu Leu
    290                 295                 300

Pro Arg Leu Ile Arg Gly Arg Val His Arg Cys Val Gly Asn Tyr Asp
305                 310                 315                 320

Gln Lys Lys Asn Ile Phe Gln Cys Val Ser Val Arg Pro Ala Ser Val
                325                 330                 335

Ser Glu Gln Lys Thr Phe Gln Ala Phe Val Lys Ile Ala Asp Val Glu
            340                 345                 350

Met Gln Tyr Tyr Ile Asn Val Met Asn Glu Thr 
        355                 360



<210> 1840
<211> 222
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1840
Met Glu Ile Pro Pro Thr Asn Tyr Pro Ala Ser Arg Ala Ala Leu Val
  1               5                  10                  15

Ala Gln Asn Tyr Ile Asn Tyr Gln Gln Gly Thr Pro His Arg Val Phe
             20                  25                  30

Glu Val Gln Lys Val Lys Gln Ala Ser Met Glu Asp Ile Pro Gly Arg
         35                  40                  45

Gly His Lys Tyr Xaa Leu Lys Phe Ala Val Glu Glu Ile Ile Gln Lys
     50                  55                  60

Gln Val Lys Val Asn Cys Thr Ala Glu Val Leu Tyr Pro Ser Thr Gly
 65                  70                  75                  80

Gln Glu Thr Ala Pro Glu Val Asn Phe Thr Phe Glu Gly Glu Thr Gly
                 85                  90                  95

Lys Asn Pro Asp Glu Glu Asp Asn Thr Phe Tyr Gln Arg Leu Lys Ser
            100                 105                 110

Met Lys Glu Pro Leu Glu Ala Gln Asn Ile Pro Asp Asn Phe Gly Asn
        115                 120                 125

Val Ser Pro Glu Met Thr Leu Val Leu His Leu Ala Trp Val Ala Cys
    130                 135                 140

Gly Tyr Ile Ile Trp Gln Asn Ser Thr Glu Asp Thr Trp Tyr Lys Met
145                 150                 155                 160

Val Lys Ile Gln Thr Val Lys Gln Val Gln Arg Asn Asp Asp Phe Ile
                165                 170                 175

Glu Leu Asp Tyr Thr Ile Leu Leu His Asn Ile Ala Ser Gln Glu Ile
            180                 185                 190

Ile Pro Trp Gln Met Gln Val Leu Trp His Pro Gln Tyr Gly Thr Lys
        195                 200                 205

Val Lys His Asn Ser Arg Leu Pro Lys Glu Val Gln Leu Glu 
    210                 215                 220



<210> 1841
<211> 279
<212> PRT
<213> Homo sapiens

<400> 1841
Met Ala Asp Asp Leu Gly Asp Glu Trp Trp Glu Asn Gln Pro Thr Gly
  1               5                  10                  15

Ala Gly Ser Ser Pro Glu Ala Ser Asp Gly Glu Gly Glu Gly Asp Thr
             20                  25                  30

Glu Val Met Gln Gln Glu Thr Val Pro Val Pro Val Pro Ser Glu Lys
         35                  40                  45

Thr Lys Gln Pro Lys Glu Cys Phe Leu Ile Gln Pro Lys Glu Arg Lys
     50                  55                  60

Glu Asn Thr Thr Lys Thr Arg Lys Arg Arg Lys Lys Lys Ile Thr Asp
 65                  70                  75                  80

Val Leu Ala Lys Ser Glu Pro Lys Pro Gly Leu Pro Glu Asp Leu Gln
                 85                  90                  95

Lys Leu Met Lys Asp Tyr Tyr Ser Ser Arg Arg Leu Val Ile Glu Leu
            100                 105                 110

Glu Glu Leu Asn Leu Pro Asp Ser Cys Phe Leu Lys Ala Asn Asp Leu
        115                 120                 125

Thr His Ser Leu Ser Ser Tyr Leu Lys Glu Ile Cys Pro Lys Trp Val
    130                 135                 140

Lys Leu Arg Lys Asn His Ser Glu Lys Lys Ser Val Leu Met Leu Ile
145                 150                 155                 160

Ile Cys Ser Ser Ala Val Arg Ala Leu Glu Leu Ile Arg Ser Met Thr
                165                 170                 175

Ala Phe Arg Gly Asp Gly Lys Val Ile Lys Leu Phe Ala Lys His Ile
            180                 185                 190

Lys Val Gln Ala Gln Val Lys Leu Leu Glu Lys Arg Val Val His Leu
        195                 200                 205

Gly Val Gly Thr Pro Gly Arg Ile Lys Glu Leu Val Lys Gln Gly Gly
    210                 215                 220

Leu Asn Leu Ser Pro Leu Lys Phe Leu Val Phe Asp Trp Asn Trp Arg
225                 230                 235                 240

Asp Gln Lys Leu Arg Arg Met Met Asp Ile Pro Glu Ile Arg Lys Glu
                245                 250                 255

Val Phe Glu Leu Leu Glu Met Gly Val Leu Ser Leu Cys Lys Ser Glu
            260                 265                 270

Ser Leu Lys Leu Gly Leu Phe 
        275



<210> 1842
<211> 368
<212> PRT
<213> Homo sapiens

<400> 1842
Met Arg Val Asn Val Asp Pro Glu Asp Leu Ile Pro Lys Leu Pro Arg
  1               5                  10                  15

Pro Arg Asp Leu Gln Pro Phe Pro Thr Cys Gln Ala Leu Val Tyr Arg
             20                  25                  30

Gly His Ser Asp Leu Val Arg Cys Leu Ser Val Ser Pro Gly Gly Gln
         35                  40                  45

Trp Leu Val Ser Gly Ser Asp Asp Gly Ser Leu Arg Leu Trp Glu Val
     50                  55                  60

Ala Thr Ala Arg Cys Val Arg Thr Val Pro Val Gly Gly Val Val Lys
 65                  70                  75                  80

Ser Val Ala Trp Asn Pro Ser Pro Ala Val Cys Leu Val Ala Ala Ala
                 85                  90                  95

Val Glu Asp Ser Val Leu Leu Leu Asn Pro Ala Leu Gly Asp Arg Leu
            100                 105                 110

Val Ala Gly Ser Thr Asp Gln Leu Leu Ser Ala Phe Val Pro Pro Glu
        115                 120                 125

Glu Pro Pro Leu Gln Pro Ala Arg Trp Leu Glu Ala Ser Glu Glu Glu
    130                 135                 140

Arg Gln Val Gly Leu Arg Leu Arg Ile Cys His Gly Lys Pro Val Thr
145                 150                 155                 160

Gln Val Thr Trp His Gly Arg Gly Asp Tyr Leu Ala Val Val Leu Ala
                165                 170                 175

Thr Gln Gly His Thr Gln Val Leu Ile His Gln Leu Ser Arg Arg Arg
            180                 185                 190

Ser Gln Ser Pro Phe Arg Arg Ser His Gly Gln Val Gln Arg Val Ala
        195                 200                 205

Phe His Pro Ala Arg Pro Phe Leu Leu Val Ala Ser Gln Arg Ser Val
    210                 215                 220

Arg Leu Tyr His Leu Leu Arg Gln Glu Leu Thr Lys Lys Leu Met Pro
225                 230                 235                 240

Asn Cys Lys Trp Val Ser Ser Leu Ala Val His Pro Ala Gly Asp Asn
                245                 250                 255

Val Ile Cys Gly Ser Tyr Asp Ser Lys Leu Val Trp Phe Asp Leu Asp
            260                 265                 270

Leu Ser Thr Lys Pro Tyr Arg Met Leu Arg His His Lys Lys Ala Leu
        275                 280                 285

Arg Ala Val Ala Phe His Pro Arg Tyr Pro Leu Phe Ala Ser Gly Ser
    290                 295                 300

Asp Asp Gly Ser Val Ile Val Cys His Gly Met Val Tyr Asn Asp Leu
305                 310                 315                 320

Leu Gln Asn Pro Leu Leu Val Pro Val Lys Val Leu Lys Gly His Val
                325                 330                 335

Leu Thr Arg Asp Leu Gly Val Leu Asp Val Ile Phe His Pro Thr Gln
            340                 345                 350

Pro Trp Val Phe Ser Ser Gly Ala Asp Gly Thr Val Arg Leu Phe Thr
        355                 360                 365






<210> 1843
<211> 104
<212> PRT
<213> Homo sapiens

<400> 1843
Met Ala Gln Gly Leu Gly Val Ser Gln Gln Val Leu Cys Asn Phe Cys
  1               5                  10                  15

Lys Thr Ser Ser Leu Leu Ala Pro Thr Cys Pro Met Leu Gly Pro Asn
             20                  25                  30

Val Gln Ser Trp Asp Leu Ser Ser Gln Asn Trp Gly Ala Glu Thr Phe
         35                  40                  45

Val Leu Leu Asp Leu Thr Leu Ser Val Pro Cys Ala Ser Val Ala Gly
     50                  55                  60

Leu Leu Pro Ala Thr Gly His Ala Ser Thr Lys Asp Thr Trp Pro Phe
 65                  70                  75                  80

Pro Val Arg Ala Asp Gly Gly Ser Phe Leu Ser His Tyr Pro Leu Gly
                 85                  90                  95

Ala Trp Glu Pro Cys Gly Trp Ile 
            100



<210> 1844
<211> 100
<212> PRT
<213> Homo sapiens

<400> 1844
Met Val Glu Gly Leu Val Leu Glu His Lys Gly Ala His Tyr Ser Asn
  1               5                  10                  15

Glu Val Tyr Glu Leu Ala Gln Val Leu Arg Trp Ala Gly Pro Glu Glu
             20                  25                  30

Arg Leu Arg Arg Val Ala Glu Arg Val Ala Ala Arg Val Gln Arg Arg
         35                  40                  45

Pro Trp Gly Ala Trp Leu Ser Ala Arg Leu Trp Lys Trp Leu Lys Ser
     50                  55                  60

Pro Arg Ser Trp Arg Leu Gly Leu Ala Leu Leu Leu Gly Gly Ala Leu
 65                  70                  75                  80

Leu Phe Trp Val Leu Leu His Arg Arg Trp Ser Glu Ala Val Ala Glu
                 85                  90                  95

Val Gly Pro Asp 
            100



<210> 1845
<211> 278
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (234)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (244)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (247)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (262)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1845
Met Gly Gln Ser Gly Arg Ser Arg His Gln Lys Arg Ala Arg Ala Gln
  1               5                  10                  15

Ala Gln Leu Arg Asn Leu Glu Ala Tyr Ala Ala Asn Pro His Ser Phe
             20                  25                  30

Val Phe Thr Arg Gly Cys Thr Gly Arg Asn Ile Arg Gln Leu Ser Leu
         35                  40                  45

Asp Val Arg Arg Val Met Glu Pro Leu Thr Ala Ser Arg Leu Gln Val
     50                  55                  60

Arg Lys Lys Asn Ser Leu Lys Asp Cys Val Ala Val Ala Gly Pro Leu
 65                  70                  75                  80

Gly Val Thr His Phe Leu Ile Leu Ser Lys Thr Glu Thr Asn Val Tyr
                 85                  90                  95

Phe Lys Leu Met Arg Leu Pro Gly Gly Pro Thr Leu Thr Phe Gln Val
            100                 105                 110

Lys Lys Tyr Ser Leu Val Arg Asp Val Val Ser Ser Leu Arg Arg His
        115                 120                 125

Arg Met His Glu Gln Gln Phe Ala His Pro Pro Leu Leu Val Leu Asn
    130                 135                 140

Ser Phe Gly Pro His Gly Met His Val Lys Leu Met Ala Thr Met Phe
145                 150                 155                 160

Gln Asn Leu Phe Pro Ser Ile Asn Val His Lys Val Asn Leu Asn Thr
                165                 170                 175

Ile Lys Arg Cys Leu Leu Ile Asp Tyr Asn Pro Asp Ser Gln Glu Leu
            180                 185                 190

Asp Phe Arg His Tyr Ser Ile Lys Val Val Pro Val Gly Ala Ser Arg
        195                 200                 205

Gly Met Lys Lys Leu Leu Gln Glu Lys Phe Pro Asn Met Ser Arg Cys
    210                 215                 220

Arg Thr Ser Ala Ser Cys Trp Pro Arg Xaa Arg Gly Cys Arg Arg Ala
225                 230                 235                 240

Arg Gln Ser Xaa Arg Arg Xaa Thr Thr Ser Gln Ser Cys Leu Arg Leu
                245                 250                 255

Ser Leu Ala Val Ala Xaa Cys Gly Pro Ser Arg Val Gln Cys Gly Ser
            260                 265                 270

Pro Arg Ser Ala Arg Gly 
        275



<210> 1846
<211> 204
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1846
Met Met Pro Ser Cys Asn Arg Ser Cys Ser Cys Ser Arg Gly Pro Ser
  1               5                  10                  15

Val Glu Asp Gly Lys Trp Tyr Gly Val Arg Ser Tyr Leu His Leu Phe
             20                  25                  30

Tyr Glu Asp Cys Ala Gly Thr Ala Xaa Ser Asp Asp Pro Glu Gly Pro
         35                  40                  45

Pro Val Leu Cys Pro Arg Arg Pro Trp Pro Ser Leu Cys Trp Lys Ile
     50                  55                  60

Ser Leu Ser Ser Gly Thr Leu Leu Leu Leu Leu Gly Val Ala Ala Leu
 65                  70                  75                  80

Thr Thr Gly Tyr Ala Val Pro Pro Lys Leu Glu Gly Ile Gly Glu Gly
                 85                  90                  95

Glu Phe Leu Val Leu Asp Gln Arg Ala Ala Asp Tyr Asn Gln Ala Leu
            100                 105                 110

Gly Thr Cys Arg Leu Ala Gly Thr Ala Leu Cys Val Ala Ala Gly Val
        115                 120                 125

Leu Leu Ala Ile Cys Leu Phe Trp Ala Met Ile Gly Trp Leu Ser Gln
    130                 135                 140

Asp Thr Lys Ala Glu Pro Leu Asp Pro Glu Ala Asp Ser His Xaa Glu
145                 150                 155                 160

Val Phe Gly Asp Glu Pro Glu Gln Gln Leu Ser Pro Ile Phe Arg Asn
                165                 170                 175

Ala Ser Gly Gln Ser Trp Phe Ser Pro Pro Ala Ser Pro Phe Gly Gln
            180                 185                 190

Ser Ser Val Gln Thr Ile Gln Pro Lys Arg Asp Ser 
        195                 200



<210> 1847
<211> 445
<212> PRT
<213> Homo sapiens

<400> 1847
Met Ser Glu Leu Thr Lys Glu Leu Met Glu Leu Val Trp Gly Thr Lys
  1               5                  10                  15

Ser Ser Pro Gly Leu Ser Asp Thr Ile Phe Cys Arg Trp Thr Gln Gly
             20                  25                  30

Phe Val Phe Ser Glu Ser Glu Gly Ser Ala Leu Glu Gln Phe Glu Gly
         35                  40                  45

Gly Pro Cys Ala Val Ile Ala Pro Val Gln Ala Phe Leu Leu Lys Lys
     50                  55                  60

Leu Leu Phe Ser Ser Glu Lys Ser Ser Trp Arg Asp Cys Ser Glu Glu
 65                  70                  75                  80

Glu Gln Lys Glu Leu Leu Cys His Thr Leu Cys Asp Ile Leu Glu Ser
                 85                  90                  95

Ala Cys Cys Asp His Ser Gly Ser Tyr Cys Leu Val Ser Trp Leu Arg
            100                 105                 110

Gly Lys Thr Thr Glu Glu Thr Ala Ser Ile Ser Gly Ser Pro Ala Glu
        115                 120                 125

Ser Ser Cys Gln Val Glu His Ser Ser Ala Leu Ala Val Glu Glu Leu
    130                 135                 140

Gly Phe Glu Arg Phe His Ala Leu Ile Gln Lys Arg Ser Phe Arg Ser
145                 150                 155                 160

Leu Pro Glu Leu Lys Asp Ala Val Leu Asp Gln Tyr Ser Met Trp Gly
                165                 170                 175

Asn Lys Phe Gly Val Leu Leu Phe Leu Tyr Ser Val Leu Leu Thr Lys
            180                 185                 190

Gly Ile Glu Asn Ile Lys Asn Glu Ile Glu Asp Ala Ser Glu Pro Leu
        195                 200                 205

Ile Asp Pro Val Tyr Gly His Gly Ser Gln Ser Leu Ile Asn Leu Leu
    210                 215                 220

Leu Thr Gly His Ala Val Ser Asn Val Trp Asp Gly Asp Arg Glu Cys
225                 230                 235                 240

Ser Gly Met Lys Leu Leu Gly Ile His Glu Gln Ala Ala Val Gly Phe
                245                 250                 255

Leu Thr Leu Met Glu Ala Leu Arg Tyr Cys Lys Val Gly Ser Tyr Leu
            260                 265                 270

Lys Ser Pro Lys Phe Pro Ile Trp Ile Val Gly Ser Glu Thr His Leu
        275                 280                 285

Thr Val Phe Phe Ala Lys Asp Met Ala Leu Val Ala Pro Glu Ala Pro
    290                 295                 300

Ser Glu Gln Ala Arg Arg Val Phe Gln Thr Tyr Asp Pro Glu Asp Asn
305                 310                 315                 320

Gly Phe Ile Pro Asp Ser Leu Leu Glu Asp Val Met Lys Ala Leu Asp
                325                 330                 335

Leu Val Ser Asp Pro Glu Tyr Ile Asn Leu Met Lys Asn Lys Leu Asp
            340                 345                 350

Pro Glu Gly Leu Gly Ile Ile Leu Leu Gly Pro Phe Leu Gln Glu Phe
        355                 360                 365

Phe Pro Asp Gln Gly Ser Ser Gly Pro Glu Ser Phe Thr Val Tyr His
    370                 375                 380

Tyr Asn Gly Leu Lys Gln Ser Asn Tyr Asn Glu Lys Val Met Tyr Val
385                 390                 395                 400

Glu Gly Thr Ala Val Val Met Gly Phe Glu Asp Pro Met Leu Gln Thr
                405                 410                 415

Asp Asp Thr Pro Ile Lys Arg Cys Leu Gln Thr Lys Trp Pro Tyr Ile
            420                 425                 430

Glu Leu Leu Trp Thr Thr Asp Arg Ser Pro Ser Leu Asn 
        435                 440                 445



<210> 1848
<211> 224
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1848
Met Ser Ala Val Gly Xaa Ala Thr Pro Tyr Leu His His Pro Gly Asp
  1               5                  10                  15

Ser His Ser Gly Arg Val Ser Phe Leu Gly Ala Gln Leu Pro Pro Glu
             20                  25                  30

Val Ala Ala Met Ala Arg Leu Leu Gly Asp Leu Asp Xaa Ser Thr Phe
         35                  40                  45

Arg Lys Leu Leu Lys Phe Val Val Ser Ser Leu Gln Gly Glu Asp Cys
     50                  55                  60

Arg Glu Xaa Leu Gln Arg Leu Gly Val Ser Ala Asn Leu Pro Glu Glu
 65                  70                  75                  80

Gln Leu Gly Ala Leu Leu Ala Gly Met His Thr Leu Leu Gln Gln Ala
                 85                  90                  95

Leu Arg Leu Pro Pro Thr Ser Leu Lys Pro Asp Thr Phe Arg Asp Gln
            100                 105                 110

Leu Gln Glu Leu Cys Ile Pro Gln Asp Leu Val Gly Asp Leu Ala Ser
        115                 120                 125

Val Val Phe Gly Xaa Pro Ala Ala Leu Leu Asp Ser Val Ala Gln Gln
    130                 135                 140

Gln Gly Ala Trp Leu Pro His Val Ala Asp Phe Arg Trp Arg Val Asp
145                 150                 155                 160

Val Ala Ile Ser Thr Ser Ala Leu Ala Arg Ser Leu Gln Pro Ser Val
                165                 170                 175

Leu Met Gln Leu Lys Leu Ser Asp Gly Ser Ala Tyr Arg Phe Glu Val
            180                 185                 190

Pro Thr Ala Lys Phe Gln Glu Leu Arg Tyr Ser Val Ala Leu Val Leu
        195                 200                 205

Lys Glu Met Ala Asp Leu Glu Lys Arg Cys Glu Arg Arg Leu Gln Asp
    210                 215                 220






<210> 1849
<211> 274
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1849
Met Cys Ala Arg Arg Leu Gly Arg Thr Arg Glu Ala Val Lys Met Met
  1               5                  10                  15

Arg Asp Leu Met Lys Glu Phe Pro Leu Leu Ser Met Phe Asn Ile His
             20                  25                  30

Glu Asn Leu Leu Glu Ala Leu Leu Glu Leu Gln Ala Tyr Ala Asp Val
         35                  40                  45

Gln Ala Val Leu Ala Lys Tyr Asp Asp Ile Ser Leu Pro Lys Ser Ala
     50                  55                  60

Thr Ile Cys Tyr Thr Ala Ala Leu Leu Lys Ala Arg Ala Val Ser Asp
 65                  70                  75                  80

Lys Phe Ser Xaa Glu Ala Ala Ser Arg Arg Gly Leu Ser Thr Ala Glu
                 85                  90                  95

Met Asn Ala Val Glu Ala Ile His Arg Ala Val Glu Phe Asn Pro His
            100                 105                 110

Val Pro Lys Tyr Leu Leu Glu Met Lys Ser Leu Ile Leu Pro Pro Glu
        115                 120                 125

His Ile Leu Lys Arg Gly Asp Xaa Glu Ala Ile Ala Tyr Ala Phe Phe
    130                 135                 140

His Leu Ala His Trp Lys Arg Val Glu Gly Ala Leu Asn Leu Leu His
145                 150                 155                 160

Cys Thr Trp Glu Gly Thr Phe Arg Met Ile Pro Tyr Pro Leu Glu Lys
                165                 170                 175

Gly His Leu Phe Tyr Pro Tyr Pro Ile Cys Thr Glu Thr Ala Asp Arg
            180                 185                 190

Glu Leu Leu Pro Ser Phe His Glu Val Ser Val Tyr Pro Lys Lys Glu
        195                 200                 205

Leu Pro Phe Phe Ile Leu Phe Thr Ala Gly Leu Cys Ser Phe Thr Ala
    210                 215                 220

Met Leu Ala Leu Leu Thr His Gln Phe Pro Glu Leu Met Gly Val Phe
225                 230                 235                 240

Ala Lys Ala Phe Leu Ser Thr Leu Phe Ala Pro Leu Asn Phe Val Met
                245                 250                 255

Glu Lys Val Glu Ser Ile Leu Pro Ser Ser Leu Trp His Gln Leu Thr
            260                 265                 270

Arg Ile 




<210> 1850
<211> 197
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1850
Met Ala Ala Gly Gly Arg Met Glu Asp Gly Ser Leu Asp Ile Thr Gln
  1               5                  10                  15

Ser Ile Glu Asp Asp Pro Leu Leu Asp Ala Gln Leu Leu Pro His His
             20                  25                  30

Ser Leu Gln Ala His Phe Arg Pro Arg Phe His Pro Leu Pro Thr Val
         35                  40                  45

Ile Ile Val Asn Leu Leu Trp Phe Ile His Leu Val Phe Val Val Leu
     50                  55                  60

Ala Phe Leu Thr Gly Val Leu Cys Ser Tyr Pro Asn Pro Asn Glu Asp
 65                  70                  75                  80

Lys Cys Pro Gly Asn Tyr Thr Asn Pro Leu Lys Val Gln Thr Val Ile
                 85                  90                  95

Ile Leu Gly Lys Val Ile Leu Trp Ile Leu His Leu Leu Leu Glu Cys
            100                 105                 110

Tyr Ile Gln Tyr Xaa His Xaa Lys Ile Arg Asn Arg Gly Tyr Asn Leu
        115                 120                 125

Ile Tyr Arg Ser Thr Arg His Leu Lys Arg Leu Ala Leu Met Ile Gln
    130                 135                 140

Ser Ser Gly Asn Thr Val Leu Leu Leu Ile Leu Cys Met Gln His Ser
145                 150                 155                 160

Phe Pro Glu Pro Gly Arg Leu Tyr Leu Asp Leu Ile Leu Ala Ile Leu
                165                 170                 175

Ala Leu Glu Leu Ile Cys Ser Leu Ile Cys Leu Leu Ile Tyr Thr Val
            180                 185                 190

Lys Ile Pro Glu Ile 
        195



<210> 1851
<211> 260
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1851
Met Gln His Leu Trp Ile Pro Leu Cys Ala Pro Asn Ser Leu Ser Gln
  1               5                  10                  15

Leu Pro Ile Thr Asp Thr Ile Arg Lys Asp Ser Lys Glu Lys Lys Lys
             20                  25                  30

Arg Lys Ala Ser Lys Leu Thr Leu Trp Gly Thr Tyr His Gly Met Thr
         35                  40                  45

Leu Xaa Ser Val Thr Glu Gly Ala Ser Ala Arg Lys Thr Gln Thr Pro
     50                  55                  60

Ala Ala Gln Pro Val Pro Arg Pro Val Ser Gln Ala Arg Pro Pro Pro
 65                  70                  75                  80

Asn Gln Lys Lys Gly Ser Arg Thr Pro Ile Ile Ile Ile Pro Ala Ala
                 85                  90                  95

Thr Thr Ser Leu Ile Thr Met Leu Asn Ala Lys Asp Leu Leu Gln Asp
            100                 105                 110

Leu Lys Phe Val Pro Ser Asp Glu Lys Lys Lys Gln Gly Cys Gln Arg
        115                 120                 125

Glu Asn Glu Thr Leu Ile Gln Arg Arg Lys Asp Gln Met Gln Pro Gly
    130                 135                 140

Gly Thr Ala Ile Ser Val Thr Val Pro Tyr Arg Val Val Asp Gln Pro
145                 150                 155                 160

Leu Lys Leu Met Pro Gln Asp Trp Asp Arg Val Val Ala Val Phe Val
                165                 170                 175

Gln Gly Pro Ala Trp Gln Phe Lys Gly Trp Pro Trp Leu Leu Pro Asp
            180                 185                 190

Gly Ser Pro Val Asp Ile Phe Ala Lys Ile Lys Ala Phe His Leu Lys
        195                 200                 205

Tyr Asp Glu Val Arg Leu Asp Pro Asn Val Gln Lys Trp Asp Val Thr
    210                 215                 220

Val Leu Glu Leu Ser Tyr His Lys Arg His Leu Asp Arg Pro Val Phe
225                 230                 235                 240

Leu Arg Phe Trp Glu Thr Leu Asp Arg Tyr Met Val Lys His Lys Ser
                245                 250                 255

His Leu Arg Phe 
            260



<210> 1852
<211> 149
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1852
Met Ser Thr Asn Ile Cys Ser Phe Lys Asp Arg Cys Val Ser Ile Leu
  1               5                  10                  15

Cys Cys Lys Phe Cys Lys Gln Val Leu Ser Ser Arg Gly Met Lys Ala
             20                  25                  30

Val Leu Leu Ala Asp Thr Glu Ile Asp Leu Phe Ser Thr Asp Ile Pro
         35                  40                  45

Pro Thr Asn Ala Val Asp Phe Thr Gly Arg Cys Tyr Phe Thr Lys Ile
     50                  55                  60

Cys Lys Cys Lys Leu Lys Asp Ile Ala Cys Leu Lys Cys Gly Asn Ile
 65                  70                  75                  80

Val Xaa Tyr His Val Ile Val Pro Cys Ser Ser Cys Leu Leu Ser Cys
                 85                  90                  95

Asn Asn Xaa His Phe Trp Met Phe His Ser Gln Ala Val Tyr Asp Ile
            100                 105                 110

Asn Arg Leu Asp Ser Thr Gly Val Asn Val Leu Leu Xaa Gly Asn Leu
        115                 120                 125

Pro Glu Ile Glu Glu Ser Thr Asp Glu Asp Val Leu Asn Ile Ser Ala
    130                 135                 140

Glu Glu Cys Ile Arg 
145



<210> 1853
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1853
Met Ala Glu Met Asn His His Val Cys Pro Val Glu Asn Trp Ser Tyr
  1               5                  10                  15

Asn Glu Ser Cys Pro Pro Asp Pro Ala Glu Gln Gly Gly Pro Lys Thr
             20                  25                  30

Cys Cys Thr Leu Asp Asp Xaa Pro Leu Ile Ser Lys Cys Gly Ser Tyr
         35                  40                  45

Pro Pro Glu Ser Cys Leu Phe Ser Leu Ile Gly Asn Met Gly Ala Phe
     50                  55                  60

Met Glu Ala Leu Ile Cys Leu Leu Arg Tyr Gly Gln Leu Leu Glu Gln
 65                  70                  75                  80

Ser Arg His Ser Trp Val Asn Thr Thr Xaa Leu Ile Thr Gly Cys Thr
                 85                  90                  95

Asn Ala Ala Gly Leu Leu Xaa Val Gly Asn Phe Gln Pro Arg Phe Arg
            100                 105                 110

Trp Ser Leu Leu Cys Pro 
        115



<210> 1854
<211> 294
<212> PRT
<213> Homo sapiens

<400> 1854
Met Asp Pro Leu Ile Ala Asn Asn Ser Gly Val Asn Lys Arg Gln Ile
  1               5                  10                  15

Thr Asp Leu Val Asp Gln Ser Ile Gln Ile Asn Ala His Cys Phe Val
             20                  25                  30

Val Thr Ala Asp Asn Arg Tyr Ile Leu Ile Cys Gly Phe Trp Asp Lys
         35                  40                  45

Ser Phe Arg Val Tyr Ser Thr Glu Thr Gly Lys Leu Thr Gln Ile Val
     50                  55                  60

Phe Gly His Trp Asp Val Val Thr Cys Leu Ala Arg Ser Glu Ser Tyr
 65                  70                  75                  80

Ile Gly Gly Asp Cys Tyr Ile Val Ser Gly Ser Arg Asp Ala Thr Leu
                 85                  90                  95

Leu Leu Trp Tyr Trp Ser Gly Arg His His Ile Ile Gly Asp Asn Pro
            100                 105                 110

Asn Ser Ser Asp Tyr Pro Ala Pro Arg Ala Val Leu Thr Gly His Asp
        115                 120                 125

His Glu Val Val Cys Val Ser Val Cys Ala Glu Leu Gly Leu Val Ile
    130                 135                 140

Ser Gly Ala Lys Glu Gly Pro Cys Leu Val His Thr Ile Thr Gly Asp
145                 150                 155                 160

Leu Leu Arg Ala Leu Glu Gly Pro Glu Asn Cys Leu Phe Pro Arg Leu
                165                 170                 175

Ile Ser Val Ser Ser Glu Gly His Cys Ile Ile Tyr Tyr Glu Arg Gly
            180                 185                 190

Arg Phe Ser Asn Phe Ser Ile Asn Gly Lys Leu Leu Ala Gln Met Glu
        195                 200                 205

Ile Asn Asp Ser Thr Arg Ala Ile Leu Leu Ser Ser Asp Gly Gln Asn
    210                 215                 220

Leu Val Thr Gly Gly Asp Asn Gly Val Val Glu Val Trp Gln Ala Cys
225                 230                 235                 240

Asp Phe Lys Gln Leu Tyr Ile Tyr Pro Gly Cys Asp Ala Gly Ile Arg
                245                 250                 255

Ala Met Asp Leu Ser His Asp Gln Arg Thr Leu Ile Thr Gly Met Ala
            260                 265                 270

Ser Gly Ser Ile Val Ala Phe Asn Ile Asp Phe Asn Arg Trp His Tyr
        275                 280                 285

Glu His Gln Asn Arg Tyr 
    290



<210> 1855
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1855
Met Lys His Ser Leu Ser Val Gly Glu Val Ile Glu Val Leu Glu Val
  1               5                  10                  15

Leu Leu Ile Phe Val Tyr Leu Asn Met Ile Leu Leu Tyr Leu Leu Pro
             20                  25                  30

Arg Cys Phe Thr Pro Gly Glu Ala Leu Leu Val Leu Gly Gly Ile Ser
         35                  40                  45

Phe Val Leu Asn Gln Leu Ile Lys Arg Ser Leu Thr Leu Val Glu Ser
     50                  55                  60

Gln Gly Asp Pro Val Asp Phe Phe Leu Leu Val Val Val Val Gly Met
 65                  70                  75                  80

Val Leu Met Gly Ile Phe Phe Ser Thr Leu Phe Val Phe Met Asp Ser
                 85                  90                  95

Gly Thr Trp Ala Ser Ser Ile Phe Phe His Leu Met Thr Cys Val Leu
            100                 105                 110

Ser Leu Gly Val Val Leu Pro Trp Leu His Arg Xaa Ile Arg Arg Ile
        115                 120                 125

Pro Cys Ser Gly Phe Phe Ser Phe Ser Ser Arg Gln Thr Pro Ala Ser
    130                 135                 140

Thr Ser 
145



<210> 1856
<211> 198
<212> PRT
<213> Homo sapiens

<400> 1856
Met Gly Pro Trp Gly Glu Pro Glu Leu Leu Val Trp Arg Pro Glu Ala
  1               5                  10                  15

Val Ala Ser Glu Pro Pro Val Pro Val Gly Leu Glu Val Lys Leu Gly
             20                  25                  30

Ala Leu Val Leu Leu Leu Val Leu Thr Leu Leu Cys Ser Leu Val Pro
         35                  40                  45

Ile Cys Val Leu Arg Arg Pro Gly Ala Asn His Glu Gly Ser Ala Ser
     50                  55                  60

Arg Gln Lys Ala Leu Ser Leu Val Ser Cys Phe Ala Gly Gly Val Phe
 65                  70                  75                  80

Leu Ala Thr Cys Leu Leu Asp Leu Leu Pro Asp Tyr Leu Ala Ala Ile
                 85                  90                  95

Asp Glu Ala Leu Ala Ala Leu His Val Thr Leu Gln Phe Pro Leu Gln
            100                 105                 110

Glu Phe Ile Leu Ala Met Gly Phe Phe Leu Val Leu Val Met Glu Gln
        115                 120                 125

Ile Thr Leu Ala Tyr Lys Glu Gln Ser Gly Pro Ser Pro Leu Glu Glu
    130                 135                 140

Thr Arg Ala Leu Leu Gly Thr Val Asn Gly Gly Pro Gln His Trp His
145                 150                 155                 160

Asp Trp Ala Arg Gly Pro Thr Gly Glu Trp Ser Pro Ser Asn Pro Leu
                165                 170                 175

Ser Leu Ala Cys Pro Val Tyr Trp Cys Ser Pro Trp Pro Ser Thr Pro
            180                 185                 190

Cys Ser Arg Gly Trp Arg 
        195



<210> 1857
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1857
Met Thr Phe Lys Ile Ile Phe Phe Lys Tyr Ile Phe Leu Ser Ser Met
  1               5                  10                  15

Thr Lys Ile Lys Met Asn Gln Gln Lys Val Ser Leu His Ile Cys Lys
             20                  25                  30

Cys Ile Tyr Pro Tyr Arg Ile Thr Cys Gln Ser Val Ala Thr Phe Phe
         35                  40                  45

His Ala His Ser Ser Leu Ala Asn Trp Leu Leu Phe Val Cys Lys Xaa
     50                  55                  60

Leu Phe Leu Ser His Pro Ile Leu Leu Ala Cys Val Lys Cys Lys Ser
 65                  70                  75                  80

Gln Val Phe Pro Ala Gly Ser Asn Val Phe Leu Ser Leu Asn Gln Gly
                 85                  90                  95

Pro Thr Gly Cys Leu Leu Leu Gln Ile Lys Phe Tyr 
            100                 105



<210> 1858
<211> 158
<212> PRT
<213> Homo sapiens

<400> 1858
Met Pro Leu Ala His Leu Leu Glu His Ile Tyr Ser Leu Ser Asp Tyr
  1               5                  10                  15

Pro Thr Pro Ile Ser Ile Ser Thr Ile Leu Phe Leu Ala Leu His Leu
             20                  25                  30

Leu Ser Asn Ile Leu Pro Ser Ser Phe Leu Leu Leu Met Phe Lys Tyr
         35                  40                  45

Phe Leu Lys Phe Ser Cys Leu Phe Cys Gln Cys Glu Thr Arg Val Val
     50                  55                  60

Ile Ser Lys Ser Leu Leu Gly Cys Ser Tyr Phe Phe Asp Leu Cys Tyr
 65                  70                  75                  80

Ser Leu Ser Lys Tyr Phe Pro Ala Ser Leu Leu Ser Val Val Leu Phe
                 85                  90                  95

Thr Ser Leu Ser Ala Ser Asn Val Phe Cys Leu Lys Ser Lys Ala His
            100                 105                 110

Trp Tyr His Ile Gln Ser Ser Ile Met Tyr Ser Ala Asn Leu Thr Tyr
        115                 120                 125

Tyr His Ala His Val Gln Phe Cys Cys Phe Gln Ser Ser Val Leu Ile
    130                 135                 140

Tyr Leu Ser Arg Lys Leu His Ser His Pro Leu Pro Leu Glu 
145                 150                 155



<210> 1859
<211> 133
<212> PRT
<213> Homo sapiens

<400> 1859
Met Gly Ser Val Thr Val Arg Tyr Phe Cys Tyr Gly Cys Leu Phe Thr
  1               5                  10                  15

Ser Ala Thr Trp Thr Val Leu Leu Phe Val Tyr Phe Asn Phe Ser Glu
             20                  25                  30

Val Thr Gln Pro Leu Lys Asn Val Pro Val Lys Gly Ser Gly Pro His
         35                  40                  45

Gly Pro Ser Pro Lys Lys Phe Tyr Pro Arg Phe Thr Arg Gly Pro Ser
     50                  55                  60

Arg Val Leu Glu Pro Gln Phe Lys Ala Asn Lys Ile Asp Asp Val Ile
 65                  70                  75                  80

Asp Ser Arg Val Glu Asp Pro Glu Glu Gly His Leu Lys Phe Ser Ser
                 85                  90                  95

Glu Leu Asp Val Lys Lys Ser Ser Thr His Leu Thr Cys Gln Leu Leu
            100                 105                 110

Val Leu Leu Ser Val Ser Ile Met Lys Arg Phe Leu Pro Cys Phe Gly
        115                 120                 125

Gln Cys Thr Val Ser 
    130



<210> 1860
<211> 145
<212> PRT
<213> Homo sapiens

<400> 1860
Met Asp Ser Asn Gly Leu Ser Asp Pro Tyr Val Lys Phe Arg Leu Gly
  1               5                  10                  15

His Gln Lys Tyr Lys Ser Lys Ile Met Pro Lys Thr Leu Asn Pro Gln
             20                  25                  30

Trp Arg Glu Gln Phe Asp Phe His Leu Tyr Glu Glu Arg Gly Gly Val
         35                  40                  45

Ile Asp Ile Thr Ala Trp Asp Lys Asp Ala Gly Lys Arg Asp Asp Phe
     50                  55                  60

Ile Gly Arg Cys Gln Val Asp Leu Ser Ala Leu Ser Arg Glu Gln Thr
 65                  70                  75                  80

His Lys Leu Glu Leu Gln Leu Glu Glu Gly Glu Gly His Leu Val Leu
                 85                  90                  95

Leu Val Thr Leu Thr Ala Ser Ala Thr Val Ser Ile Ser Asp Leu Ser
            100                 105                 110

Val Asn Ser Leu Glu Asp Gln Lys Glu Arg Glu Glu Ile Leu Lys Arg
        115                 120                 125

Tyr Ser Pro Leu Arg Ile Phe His Asn Leu Lys Asp Val Gly Phe Leu
    130                 135                 140

Gln 
145



<210> 1861
<211> 189
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1861
Met Ala Ala Ala Lys Val Ala Leu Thr Lys Arg Ala Asp Pro Ala Glu
  1               5                  10                  15

Leu Arg Thr Ile Phe Leu Lys Tyr Ala Ser Ile Glu Lys Asn Gly Glu
             20                  25                  30

Phe Phe Met Ser Pro Asn Asp Phe Val Thr Arg Tyr Leu Asn Ile Phe
         35                  40                  45

Gly Glu Ser Gln Pro Asn Pro Lys Thr Val Glu Leu Leu Ser Gly Val
     50                  55                  60

Val Asp Gln Thr Lys Asp Gly Leu Ile Ser Phe Gln Glu Phe Val Ala
 65                  70                  75                  80

Phe Glu Ser Val Leu Cys Ala Pro Asp Ala Leu Phe Met Val Ala Phe
                 85                  90                  95

Gln Leu Phe Asp Lys Ala Gly Lys Gly Glu Val Thr Phe Glu Asp Val
            100                 105                 110

Lys Gln Val Phe Gly Gln Thr Thr Ile His Gln His Ile Pro Phe Asn
        115                 120                 125

Trp Asp Ser Glu Phe Val Gln Leu His Phe Gly Lys Glu Arg Lys Arg
    130                 135                 140

His Leu Thr Tyr Ala Glu Phe Thr Gln Phe Leu Phe Gly Asn Pro Leu
145                 150                 155                 160

Glu His Ala Lys Gln Ala Phe Val His Xaa Ala Met Leu Gly Leu Gly
                165                 170                 175

Gly Xaa Ser His Arg Phe Arg Ala Ser Gly Thr Ser Ala 
            180                 185



<210> 1862
<211> 115
<212> PRT
<213> Homo sapiens

<400> 1862
Met Glu Ala Gly Leu Cys Leu Lys Ala Val Leu Tyr Gln Val Leu Glu
  1               5                  10                  15

Met Lys Gly Ile His Ser Val Leu Gln Lys Arg Phe Cys Gly Leu Ile
             20                  25                  30

Gln Lys His Gln Gln His Gln Arg Gly Gly Asp Ser Phe Leu Ser Arg
         35                  40                  45

Phe Tyr Ser Leu Ala Leu Ser Pro Val Lys Gln Leu Pro Ser Thr Ala
     50                  55                  60

Ser Ala Gly Ser Ser Leu Asp Lys Gly Arg Lys Pro Ala Arg Val Gly
 65                  70                  75                  80

Ala Ile Gly Ser Ala Gly Met Ser His Cys Trp Arg Ser Leu Val Phe
                 85                  90                  95

Cys Leu Phe Leu Phe Cys Phe Val Leu Phe Phe Glu Thr Gly Ser Arg
            100                 105                 110

Ser Val Ala 
        115



<210> 1863
<211> 322
<212> PRT
<213> Homo sapiens

<400> 1863
Met Pro Ile Thr Leu Leu Asp Asn Ile Ile Ala Gly Trp Pro Phe Gly
  1               5                  10                  15

Asn Thr Met Cys Lys Ile Ser Gly Leu Val Gln Gly Ile Ser Val Ala
             20                  25                  30

Ala Ser Val Phe Thr Leu Val Ala Ile Ala Val Asp Arg Phe Gln Cys
         35                  40                  45

Val Val Tyr Pro Phe Lys Pro Lys Leu Thr Ile Lys Thr Ala Phe Val
     50                  55                  60

Ile Ile Met Ile Ile Trp Val Leu Ala Ile Thr Ile Met Ser Pro Ser
 65                  70                  75                  80

Ala Val Met Leu His Val Gln Glu Glu Lys Tyr Tyr Arg Val Arg Leu
                 85                  90                  95

Asn Ser Gln Asn Lys Thr Ser Pro Val Tyr Trp Cys Arg Glu Asp Trp
            100                 105                 110

Pro Asn Gln Glu Met Arg Lys Ile Tyr Thr Thr Val Leu Phe Ala Asn
        115                 120                 125

Ile Tyr Leu Ala Pro Leu Ser Leu Ile Val Ile Met Tyr Gly Arg Ile
    130                 135                 140

Gly Ile Ser Leu Phe Arg Ala Ala Val Pro His Thr Gly Arg Lys Asn
145                 150                 155                 160

Gln Glu Gln Trp His Val Val Ser Arg Lys Lys Gln Lys Ile Ile Lys
                165                 170                 175

Met Leu Leu Ile Val Ala Leu Leu Phe Ile Leu Ser Trp Leu Pro Leu
            180                 185                 190

Trp Thr Leu Met Met Leu Ser Asp Tyr Ala Asp Leu Ser Pro Asn Glu
        195                 200                 205

Leu Gln Ile Ile Asn Ile Tyr Ile Tyr Pro Phe Ala His Trp Leu Ala
    210                 215                 220

Phe Gly Asn Ser Ser Val Asn Pro Ile Ile Tyr Gly Phe Phe Asn Glu
225                 230                 235                 240

Asn Phe Arg Arg Gly Phe Gln Glu Ala Phe Gln Leu Gln Leu Cys Gln
                245                 250                 255

Lys Arg Ala Lys Pro Met Glu Ala Tyr Ala Leu Lys Ala Lys Ser His
            260                 265                 270

Val Leu Ile Asn Thr Ser Asn Gln Leu Val Gln Glu Ser Thr Phe Gln
        275                 280                 285

Asn Pro His Gly Glu Thr Leu Leu Tyr Arg Lys Ser Ala Glu Lys Pro
    290                 295                 300

Gln Gln Glu Leu Val Met Glu Glu Leu Lys Glu Thr Thr Asn Ser Ser
305                 310                 315                 320

Glu Ile 




<210> 1864
<211> 229
<212> PRT
<213> Homo sapiens

<400> 1864
Met Val Trp Asn Ser Glu Glu Ile Gln Gln Gln Ile Trp Ile Pro Ser
  1               5                  10                  15

Val Phe Ile Gly Glu Arg Ser Ser Glu Tyr Leu Arg Ala Leu Phe Val
             20                  25                  30

Tyr Glu Lys Gly Ala Arg Val Leu Leu Val Pro Asp Asn Thr Phe Pro
         35                  40                  45

Leu Gly Tyr Tyr Leu Ile Pro Phe Thr Gly Ile Val Gly Leu Leu Val
     50                  55                  60

Leu Ala Met Gly Ala Val Met Ile Ala Arg Cys Ile Gln His Arg Lys
 65                  70                  75                  80

Arg Leu Gln Arg Asn Arg Leu Thr Lys Glu Gln Leu Lys Gln Ile Pro
                 85                  90                  95

Thr His Asp Tyr Gln Lys Gly Asp Gln Tyr Asp Val Cys Ala Ile Cys
            100                 105                 110

Leu Asp Glu Tyr Glu Asp Gly Asp Lys Leu Arg Val Leu Pro Cys Ala
        115                 120                 125

His Ala Tyr His Ser Arg Cys Val Asp Pro Trp Leu Thr Gln Thr Arg
    130                 135                 140

Lys Thr Cys Pro Ile Cys Lys Gln Pro Val His Arg Gly Pro Gly Asp
145                 150                 155                 160

Glu Asp Gln Glu Glu Glu Thr Gln Gly Gln Glu Glu Gly Asp Glu Gly
                165                 170                 175

Glu Pro Arg Asp His Pro Ala Ser Glu Arg Thr Pro Leu Leu Gly Ser
            180                 185                 190

Ser Pro Thr Leu Pro Thr Ser Phe Gly Ser Leu Ala Pro Ala Pro Leu
        195                 200                 205

Val Phe Pro Gly Pro Ser Thr Asp Pro Pro Leu Ser Pro Pro Ser Ser
    210                 215                 220

Pro Val Ile Leu Val 
225



<210> 1865
<211> 201
<212> PRT
<213> Homo sapiens

<400> 1865
Met Thr Leu Arg Pro Ser Leu Leu Pro Leu His Leu Leu Leu Leu Leu
  1               5                  10                  15

Leu Leu Ser Ala Ala Val Cys Arg Ala Glu Ala Gly Leu Glu Thr Glu
             20                  25                  30

Ser Pro Val Arg Thr Leu Gln Val Glu Thr Leu Val Glu Pro Pro Glu
         35                  40                  45

Pro Cys Ala Glu Pro Ala Ala Phe Gly Asp Thr Leu His Ile His Tyr
     50                  55                  60

Thr Gly Ser Leu Val Asp Gly Arg Ile Ile Asp Thr Ser Leu Thr Arg
 65                  70                  75                  80

Asp Pro Leu Val Ile Glu Leu Gly Gln Lys Gln Val Ile Pro Gly Leu
                 85                  90                  95

Glu Gln Ser Leu Leu Asp Met Cys Val Gly Glu Lys Arg Arg Ala Ile
            100                 105                 110

Ile Pro Ser His Leu Ala Tyr Gly Lys Arg Gly Phe Pro Pro Ser Val
        115                 120                 125

Pro Ala Asp Ala Val Val Gln Tyr Asp Val Glu Leu Ile Ala Leu Ile
    130                 135                 140

Arg Ala Asn Tyr Trp Leu Lys Leu Val Lys Gly Ile Leu Pro Leu Val
145                 150                 155                 160

Gly Met Ala Met Val Pro Ala Leu Leu Gly Leu Ile Gly Tyr His Leu
                165                 170                 175

Tyr Arg Lys Ala Asn Arg Pro Lys Val Ser Lys Lys Lys Leu Lys Glu
            180                 185                 190

Glu Lys Arg Asn Lys Ser Lys Lys Lys 
        195                 200



<210> 1866
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1866
Met Val Asn Glu Ser Ser Leu Thr Gly Glu Ser Ile Pro Val Leu Lys
  1               5                  10                  15

Thr Ala Leu Pro Glu Gly Leu Gly Pro Tyr Cys Ala Glu Thr His Arg
             20                  25                  30

Arg His Thr Leu Phe Cys Gly Thr Leu Ile Leu Gln Ala Arg Ala Tyr
         35                  40                  45

Val Gly Pro His Val Leu Ala Val Val Thr Arg Thr Gly Phe Cys Thr
     50                  55                  60

Ala Lys Gly Gly Leu Val Xaa Ser Ile Leu Xaa Pro Arg Pro Ile Asn
 65                  70                  75                  80

Phe Lys Phe Tyr Lys His Ser Met Lys Phe Val Ala Ala Leu Ser Val
                 85                  90                  95

Leu Ala Leu Leu Gly Thr Ile Tyr Ser Ile Xaa Ile Leu Tyr Arg Xaa
            100                 105                 110

Arg Val Pro Leu Lys 
        115



<210> 1867
<211> 134
<212> PRT
<213> Homo sapiens

<400> 1867
Met Leu Leu Leu Ala Ala Pro Thr Leu Tyr Ile Phe Ser Thr Ile Ser
  1               5                  10                  15

Lys Met Gly Leu Glu Ala Thr Ile Ala Met Leu Leu Leu Ser Gly Ala
             20                  25                  30

Leu Val Ser Gly Pro Tyr Thr Leu Ile Thr Thr Ala Val Ser Ala Asp
         35                  40                  45

Leu Gly Thr His Lys Ser Leu Lys Gly Asn Ala His Ala Leu Ser Thr
     50                  55                  60

Val Thr Ala Ile Ile Asp Gly Thr Gly Ser Val Gly Ala Ala Leu Gly
 65                  70                  75                  80

Pro Leu Leu Ala Gly Leu Leu Ser Pro Ser Gly Trp Ser Asn Val Phe
                 85                  90                  95

Tyr Met Leu Met Phe Ala Asp Ala Cys Ala Leu Leu Phe Leu Ile Arg
            100                 105                 110

Leu Ile His Lys Glu Leu Ser Cys Pro Gly Ser Ala Thr Gly Asp Gln
        115                 120                 125

Val Pro Phe Lys Glu Gln 
    130



<210> 1868
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1868
Met Gln Trp Pro Met Cys Thr Phe Met Pro His Ser Cys Leu Gly Ser
  1               5                  10                  15

Thr Gln Ser Pro Ile Pro Ser Cys Ala His Ala Ile Cys Ala Leu Leu
             20                  25                  30

Ser Ala Ser Lys Gly Arg Trp Gln Ser Pro Pro Phe Arg Ala Thr Gly
         35                  40                  45

Ala Leu Cys Val Gly Gly Ser Leu Gly Cys Cys Leu Trp Cys Leu Gln
     50                  55                  60

Lys Pro Phe Arg Met Pro Ser Gly Ala Xaa Pro Ser Thr Arg Arg Val
 65                  70                  75                  80

Leu Ser Thr Ala Val Ala Gln Glu Pro Ser Leu Xaa Ser His Glu Met
                 85                  90                  95

Thr Pro Leu Leu Phe Xaa Ala Glu Gly Val Xaa Val Phe Ser Lys 
            100                 105                 110



<210> 1869
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1869
Met His Pro Cys Arg Asn Lys Glu Trp Val Ala Cys Pro Ala Gln His
  1               5                  10                  15

His Xaa Leu Ser Pro Ala Arg Glu Arg Pro Pro Lys Xaa Gln Gly Ser
             20                  25                  30

Ser Cys Phe Leu Gly Ser Val Thr Leu Glu Ser Glu Pro Ala Xaa Gln
         35                  40                  45

Glu Leu Pro Gln Lys Arg Lys Thr Lys Lys Ser Pro Pro Ser Gln Gly
     50                  55                  60

Leu Leu Leu Gln Gly Leu Ala Pro Ser Leu Ala Phe Gly Ser Cys Leu
 65                  70                  75                  80

Phe Pro His Ser Trp Ser Leu Ile Phe Gly Ala Thr Ser Gly Glu Ser
                 85                  90                  95

Pro Gly Pro Gln Ser Leu 
            100



<210> 1870
<211> 247
<212> PRT
<213> Homo sapiens

<400> 1870
Met Leu Arg Phe Ile Gln Lys Phe Ser Gln Ala Ser Ser Lys Ile Leu
  1               5                  10                  15

Lys Tyr Ser Phe Pro Val Gly Leu Arg Thr Ser Arg Thr Asp Ile Leu
             20                  25                  30

Ser Leu Lys Met Ser Leu Gln Gln Asn Phe Ser Pro Cys Pro Arg Pro
         35                  40                  45

Trp Leu Ser Ser Ser Phe Pro Ala Tyr Met Ser Lys Thr Gln Cys Tyr
     50                  55                  60

His Thr Ser Pro Cys Ser Phe Lys Lys Gln Gln Lys Gln Ala Leu Leu
 65                  70                  75                  80

Ala Arg Pro Ser Ser Thr Ile Thr Tyr Leu Thr Asp Ser Pro Lys Pro
                 85                  90                  95

Ala Leu Cys Val Thr Leu Ala Gly Leu Ile Pro Phe Val Ala Pro Pro
            100                 105                 110

Leu Val Met Leu Met Thr Lys Thr Tyr Ile Pro Ile Leu Ala Phe Thr
        115                 120                 125

Gln Met Ala Tyr Gly Ala Ser Phe Leu Ser Phe Leu Gly Gly Ile Arg
    130                 135                 140

Trp Gly Phe Ala Leu Pro Glu Gly Ser Pro Ala Lys Pro Asp Tyr Leu
145                 150                 155                 160

Asn Leu Ala Ser Ser Ala Ala Pro Leu Phe Phe Ser Trp Phe Ala Phe
                165                 170                 175

Leu Ile Ser Glu Arg Leu Ser Glu Ala Ile Val Thr Val Ile Met Gly
            180                 185                 190

Met Gly Val Ala Phe His Leu Glu Leu Phe Leu Leu Pro His Tyr Pro
        195                 200                 205

Asn Trp Phe Lys Ala Leu Arg Ile Val Val Thr Leu Leu Ala Thr Phe
    210                 215                 220

Ser Phe Ile Ile Thr Leu Val Val Lys Ser Ser Phe Pro Glu Lys Gly
225                 230                 235                 240

His Lys Arg Pro Gly Gln Val 
                245



<210> 1871
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1871
Met Ala Met Gly Gly Ser Ala Pro Ser Phe Met Ala Lys Met Ser Arg
  1               5                  10                  15

Gln His Val Pro Tyr Ala Gly Ile Leu Ala Thr Leu Val Val Tyr Val
             20                  25                  30

Val Gly Val Phe Leu Asn Tyr Leu Val Pro Ser Arg Val Phe Glu Ile
         35                  40                  45

Val Leu Asn Phe Ala Ser Leu Gly Ile Ile Ala Ser Trp Ala Phe Ile
     50                  55                  60

Ile Val Cys Gln Met Arg Leu Arg Lys Ala Ile Lys Glu Gly Lys Ala
 65                  70                  75                  80

Ala Asp Val Ser Phe Lys Leu Pro Gly Ala Pro Phe Thr Ser Trp Leu
                 85                  90                  95

Thr Leu Leu Val Leu Leu Ser Val Leu Val Leu Met Ala Phe Asp Tyr
            100                 105                 110

Pro Asn Gly Thr Tyr Thr Ile Ala Ala Leu Pro Ile Ile Gly Ile Leu
        115                 120                 125

Leu Val Ile Gly Trp Phe Gly Val Arg Lys Arg Val Ala Glu Ile His
    130                 135                 140

Ser Thr Ala Pro Val Val Glu Glu Asp Glu Glu Lys Gln Glu Ile Val
145                 150                 155                 160

Xaa Lys Pro Glu Thr Ala Ser 
                165



<210> 1872
<211> 114
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1872
Met His Lys Lys Met Thr Cys Val Gly Gln Lys Ser Glu Lys Gly Tyr
  1               5                  10                  15

Gln Ala Leu Asn Arg Arg Glu Arg Arg Val Cys Phe Gln Arg Leu Ser
             20                  25                  30

Tyr Ser Phe Lys Gly Leu Ile Met Lys Leu Asn Phe Lys Gly Phe Phe
         35                  40                  45

Lys Ala Ala Gly Leu Phe Pro Leu Ala Leu Met Leu Ser Gly Cys Ile
     50                  55                  60

Ser Tyr Ala Leu Val Ser His Thr Ala Lys Gly Ser Ser Xaa Lys Tyr
 65                  70                  75                  80

Gln Ser Gln Ser Asp Thr Ile Thr Gly Leu Ser Gln Ala Lys Asp Ser
                 85                  90                  95

Asn Gly Thr Lys Xaa Tyr Gly Phe Cys Xaa Gly Ile Ala Gly Leu Pro
            100                 105                 110

Tyr His 




<210> 1873
<211> 134
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1873
Met Trp Gln Ser Cys Leu Leu Lys Leu Asn Thr Arg Met Lys Ser Val
  1               5                  10                  15

Val Leu Val Lys Asn Xaa Tyr Asn Ile Leu Phe Leu Leu Met Tyr Pro
             20                  25                  30

Glu Leu Leu His Ser Pro Leu Thr Ala Ala Tyr Tyr Phe Ile Leu Leu
         35                  40                  45

Ser Gln Leu Leu Ser Cys Ser Ile Pro Glu Tyr Leu Pro Thr Glu Gly
     50                  55                  60

Glu Leu Leu Pro Phe Leu Phe Leu Thr Val Trp Leu Trp Leu Tyr Lys
 65                  70                  75                  80

Leu Leu Phe Gly Glu Ser Pro Arg Tyr Pro Asn Val Ile Gly Lys Thr
                 85                  90                  95

Tyr Phe Phe Phe Trp Thr Asp Gln Ile Ser Arg Glu Ser Arg Phe Leu
            100                 105                 110

Glu Arg Leu Ala Phe Ile Val Ser Glu Asn Cys Leu Ile Phe Leu Ile
        115                 120                 125

His Ala Ile Thr Gly Gln 
    130



<210> 1874
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1874
Met Ser Thr Thr Asn Val Arg Lys Leu Met Asn Cys Gly Gly Phe Gly
  1               5                  10                  15

Met Glu Ala Thr Leu Leu Leu Val Val Gly Tyr Ser His Ser Lys Gly
             20                  25                  30

Val Ala Xaa Ser Phe Leu Val Leu Ala Val Ala Ser Ala Ala Ser His
         35                  40                  45

Leu Trp Val Gln Arg Glu Pro Pro Gly His Ser Pro Ala Leu Arg Gln
     50                  55                  60

His Pro His Gly His Leu Gln Arg Arg Gly His Thr Val Gly His Gly
 65                  70                  75                  80

Val Pro Ile Ile Val Gly Ala Met Thr Lys His Lys Thr Arg Glu Glu
                 85                  90                  95

Trp Gln Tyr Val Phe Leu Ile Ala Ser Leu Val His Tyr Gly Gly Val
            100                 105                 110

Ile Phe Tyr Gly Val Phe Ala Ser Gly Glu Lys Gln Pro Trp Ala Glu
        115                 120                 125

Leu Arg Arg 
    130



<210> 1875
<211> 165
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (37)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1875
Met Ala Asp Phe Asp Glu Ile Tyr Glu Glu Glu Glu Asp Glu Glu Arg
  1               5                  10                  15

Ala Leu Glu Glu Gln Leu Leu Lys Tyr Ser Pro Asp Pro Val Val Val
             20                  25                  30

Arg Gly Ser Gly Xaa Val Thr Val Phe Gly Leu Ser Asn Lys Phe Glu
         35                  40                  45

Ser Glu Phe Pro Ser Ser Leu Thr Gly Lys Val Ala Pro Glu Glu Phe
     50                  55                  60

Lys Ala Ser Ile Asn Arg Val Asn Ser Cys Leu Lys Lys Asn Leu Pro
 65                  70                  75                  80

Val Asn Val Arg Trp Leu Leu Cys Gly Cys Leu Cys Cys Cys Cys Thr
                 85                  90                  95

Leu Gly Cys Ser Met Trp Pro Val Ile Cys Leu Ser Lys Arg Thr Arg
            100                 105                 110

Arg Ser Ile Glu Lys Leu Leu Glu Trp Glu Asn Asn Arg Leu Tyr His
        115                 120                 125

Lys Leu Cys Leu His Trp Arg Leu Ser Lys Arg Lys Cys Glu Thr Asn
    130                 135                 140

Asn Met Met Glu Tyr Val Ile Leu Ile Glu Phe Leu Pro Lys Thr Pro
145                 150                 155                 160

Ile Phe Arg Pro Asp 
                165



<210> 1876
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1876
Met Tyr Cys Ala Glu Val Ala Ala Val His Ile His Ser Val Cys Gln
  1               5                  10                  15

His Arg Ile Ser Ser Phe Leu Thr Gln Leu Ser Val Ile Lys Ile Ser
             20                  25                  30

Tyr Trp Met Phe Pro Leu Gly Thr Gly Ser Ser Leu Ala Pro Trp Gln
         35                  40                  45

Glu Asn Arg Ile Ala Asn His Lys Ser Arg Ala Leu Thr Pro Ala Leu
     50                  55                  60

Met Leu Leu Cys Phe Val Thr Leu Cys Arg Gln Leu Tyr Ile Pro Ile
 65                  70                  75                  80

Ser Gly His Ser Pro Pro Tyr Xaa Gly Gly Glu Gly His Leu Ala Leu
                 85                  90                  95

Xaa Met Ser Ala Trp Leu Xaa 
            100



<210> 1877
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1877
Met Val Ser Gly Pro Gly Gly Gly Gly Arg Gly Val Arg Pro Gly Trp
  1               5                  10                  15

Gly Arg Pro Trp Cys Gln Ala Arg Val Gly Ala Ala Val Leu Pro Gly
             20                  25                  30

Pro Gly Gly Gly Gly Leu Gly Val Arg Pro Gly Trp Gly Arg Pro Trp
         35                  40                  45

Cys Gln Ala Arg Val Gly Ala Arg Ala Arg Gly Gln Arg Trp Glu Ser
     50                  55                  60

Pro Cys Gly Leu Asp Gln Leu Lys Ala Arg Ile Cys Ile Leu Lys Val
 65                  70                  75                  80

Ala Lys Pro Gly Leu Arg Ala Arg Ala Phe Thr Leu Asp Lys Lys His
                 85                  90                  95

Phe Leu Glu Leu Gln Lys Met Leu Pro Arg Thr Leu Phe Pro Leu Ser
            100                 105                 110

Leu Ser Leu Tyr Phe Phe Phe Phe Gly Tyr Gly Val Ser Leu Leu Leu
        115                 120                 125

Pro Ser Xaa Glu Val Ala Val Ser Arg Asp Arg Ala Ile 
    130                 135                 140



<210> 1878
<211> 158
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1878
Met Arg Pro Ala Leu Ala Val Gly Leu Val Phe Ala Gly Cys Cys Ser
  1               5                  10                  15

Asn Val Ile Phe Leu Glu Leu Leu Ala Arg Lys His Pro Gly Cys Gly
             20                  25                  30

Asn Ile Val Thr Phe Ala Gln Phe Leu Phe Ile Ala Val Glu Gly Phe
         35                  40                  45

Leu Phe Glu Ala Asp Leu Gly Arg Lys Arg Pro Ala Ile Pro Ile Arg
     50                  55                  60

Tyr Tyr Ala Val Met Val Thr Met Xaa Phe Thr Val Ser Val Val Asn
 65                  70                  75                  80

Asn Tyr Ala Leu Asn Leu Asn Ile Ala Met Pro Leu His Met Ile Phe
                 85                  90                  95

Arg Ser Gly Ser Leu Ile Ala Asn Met Ile Leu Gly Ile Ile Ile Leu
            100                 105                 110

Lys Lys Arg Tyr Ser Ile Phe Lys Tyr Thr Ser Ile Ala Leu Val Ser
        115                 120                 125

Val Gly Ile Phe Ile Cys Thr Phe Met Ser Ala Lys Gln Val Thr Phe
    130                 135                 140

Pro Val Gln Leu Gly Val Arg Met Met Asp Ser Arg His Phe 
145                 150                 155



<210> 1879
<211> 830
<212> PRT
<213> Homo sapiens

<400> 1879
Met Val Glu Glu Glu Asn Ile Arg Val Val Arg Cys Gly Gly Ser Glu
  1               5                  10                  15

Leu Asn Phe Arg Arg Ala Val Phe Ser Ala Asp Ser Lys Tyr Ile Phe
             20                  25                  30

Cys Val Ser Gly Asp Phe Val Lys Val Tyr Ser Thr Val Thr Glu Glu
         35                  40                  45

Cys Val His Ile Leu His Gly His Arg Asn Leu Val Thr Gly Ile Gln
     50                  55                  60

Leu Asn Pro Asn Asn His Leu Gln Leu Tyr Ser Cys Ser Leu Asp Gly
 65                  70                  75                  80

Thr Ile Lys Leu Trp Asp Tyr Ile Asp Gly Ile Leu Ile Lys Thr Phe
                 85                  90                  95

Ile Val Gly Cys Lys Leu His Ala Leu Phe Thr Leu Ala Gln Ala Glu
            100                 105                 110

Asp Ser Val Phe Val Ile Val Asn Lys Glu Lys Pro Asp Ile Phe Gln
        115                 120                 125

Leu Val Ser Val Lys Leu Pro Lys Ser Ser Ser Gln Glu Val Glu Ala
    130                 135                 140

Lys Glu Leu Ser Phe Val Leu Asp Tyr Ile Asn Gln Ser Pro Lys Cys
145                 150                 155                 160

Ile Ala Phe Gly Asn Glu Gly Val Tyr Val Ala Ala Val Arg Glu Phe
                165                 170                 175

Tyr Leu Ser Val Tyr Phe Phe Lys Lys Lys Thr Thr Ser Arg Phe Thr
            180                 185                 190

Leu Ser Ser Ser Arg Asn Lys Lys His Ala Lys Asn Asn Phe Thr Cys
        195                 200                 205

Val Ala Cys His Pro Thr Glu Asp Cys Ile Ala Ser Gly His Met Asp
    210                 215                 220

Gly Lys Ile Arg Leu Trp Arg Asn Phe Tyr Asp Asp Lys Lys Tyr Thr
225                 230                 235                 240

Tyr Thr Cys Leu His Trp His His Asp Met Val Met Asp Leu Ala Phe
                245                 250                 255

Ser Val Thr Gly Thr Ser Leu Leu Ser Gly Gly Arg Glu Ser Val Leu
            260                 265                 270

Val Glu Trp Arg Asp Ala Thr Glu Lys Asn Lys Glu Phe Leu Pro Arg
        275                 280                 285

Leu Gly Ala Thr Ile Glu His Ile Ser Val Ser Pro Ala Gly Asp Leu
    290                 295                 300

Phe Cys Thr Ser His Ser Asp Asn Lys Ile Ile Ile Ile His Arg Asn
305                 310                 315                 320

Leu Glu Ala Ser Ala Val Ile Gln Gly Leu Val Lys Asp Arg Ser Ile
                325                 330                 335

Phe Thr Gly Leu Met Ile Asp Pro Arg Thr Lys Ala Leu Val Leu Asn
            340                 345                 350

Gly Lys Pro Gly His Leu Gln Phe Tyr Ser Leu Gln Ser Asp Lys Gln
        355                 360                 365

Leu Tyr Asn Leu Asp Ile Ile Gln Gln Glu Tyr Ile Asn Asp Tyr Gly
    370                 375                 380

Leu Ile Gln Ile Glu Leu Thr Lys Ala Ala Phe Gly Cys Phe Gly Asn
385                 390                 395                 400

Trp Leu Ala Thr Val Glu Gln Arg Gln Glu Lys Glu Thr Glu Leu Glu
                405                 410                 415

Leu Gln Met Lys Leu Trp Met Tyr Asn Lys Lys Thr Gln Gly Phe Ile
            420                 425                 430

Leu Asn Thr Lys Ile Asn Met Pro His Glu Asp Cys Ile Thr Ala Leu
        435                 440                 445

Cys Phe Cys Asn Ala Glu Lys Ser Glu Gln Pro Thr Leu Val Thr Ala
    450                 455                 460

Ser Lys Asp Gly Tyr Phe Lys Val Trp Ile Leu Thr Asp Asp Ser Asp
465                 470                 475                 480

Ile Tyr Lys Lys Ala Val Gly Trp Thr Cys Asp Phe Val Gly Ser Tyr
                485                 490                 495

His Lys Tyr Gln Ala Thr Asn Cys Cys Phe Ser Glu Asp Gly Ser Leu
            500                 505                 510

Leu Ala Val Ser Phe Glu Glu Ile Val Thr Ile Trp Asp Ser Val Thr
        515                 520                 525

Trp Glu Leu Lys Cys Thr Phe Cys Gln Arg Ala Gly Lys Ile Arg His
    530                 535                 540

Leu Cys Phe Gly Arg Leu Thr Cys Ser Lys Tyr Leu Leu Gly Ala Thr
545                 550                 555                 560

Glu Asn Gly Ile Leu Cys Cys Trp Asn Leu Leu Ser Cys Ala Leu Glu
                565                 570                 575

Trp Asn Ala Lys Leu Asn Val Arg Val Met Glu Pro Asp Pro Asn Ser
            580                 585                 590

Glu Asn Ile Ala Ala Ile Ser Gln Ser Ser Val Gly Ser Asp Leu Phe
        595                 600                 605

Val Phe Lys Pro Ser Glu Pro Arg Pro Leu Tyr Ile Gln Lys Gly Ile
    610                 615                 620

Ser Arg Glu Lys Val Gln Trp Gly Val Phe Val Pro Arg Asp Val Pro
625                 630                 635                 640

Glu Ser Phe Thr Ser Glu Ala Tyr Gln Trp Leu Asn Arg Ser Gln Phe
                645                 650                 655

Tyr Phe Leu Thr Lys Ser Gln Ser Leu Leu Thr Phe Ser Thr Lys Ser
            660                 665                 670

Pro Glu Glu Lys Leu Thr Pro Thr Ser Lys Gln Leu Leu Ala Glu Glu
        675                 680                 685

Ser Leu Pro Thr Thr Pro Phe Tyr Phe Ile Leu Gly Lys His Arg Gln
    690                 695                 700

Gln Gln Asp Glu Lys Leu Asn Glu Thr Leu Glu Asn Glu Leu Val Gln
705                 710                 715                 720

Leu Pro Leu Thr Glu Asn Ile Pro Ala Ile Ser Glu Leu Leu His Thr
                725                 730                 735

Pro Ala His Val Leu Pro Ser Ala Ala Phe Leu Cys Ser Met Phe Val
            740                 745                 750

Asn Ser Leu Leu Leu Ser Lys Glu Thr Lys Ser Ala Lys Glu Ile Pro
        755                 760                 765

Glu Asp Val Asp Met Glu Glu Glu Lys Glu Ser Glu Asp Ser Asp Glu
    770                 775                 780

Glu Asn Asp Phe Thr Glu Lys Val Gln Asp Thr Ser Asn Thr Gly Leu
785                 790                 795                 800

Gly Glu Asp Ile Ile His Gln Leu Ser Lys Ser Glu Glu Lys Glu Leu
                805                 810                 815

Arg Lys Phe Arg Lys Ile Asp Tyr Ser Trp Ile Ala Ala Leu 
            820                 825                 830



<210> 1880
<211> 195
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1880
Met Ala Pro Ala Ala Ser Arg Leu Arg Ala Glu Ala Gly Leu Gly Ala
  1               5                  10                  15

Leu Pro Arg Arg Ala Leu Ala Gln Tyr Leu Leu Phe Leu Arg Leu Tyr
             20                  25                  30

Pro Val Leu Thr Lys Ala Ala Thr Ser Gly Ile Leu Ser Ala Leu Gly
         35                  40                  45

Asn Xaa Leu Ala Gln Met Ile Glu Lys Lys Arg Lys Lys Glu Asn Ser
     50                  55                  60

Arg Ser Leu Asp Val Gly Gly Pro Leu Arg Tyr Ala Val Tyr Gly Phe
 65                  70                  75                  80

Phe Phe Thr Gly Pro Leu Ser His Phe Phe Tyr Phe Phe Met Glu His
                 85                  90                  95

Trp Ile Pro Pro Glu Val Pro Leu Ala Gly Leu Arg Arg Leu Leu Leu
            100                 105                 110

Asp Arg Leu Val Phe Ala Pro Ala Phe Leu Met Leu Phe Phe Leu Ile
        115                 120                 125

Met Asn Phe Leu Glu Gly Lys Asp Ala Ser Ala Phe Ala Ala Lys Met
    130                 135                 140

Arg Gly Gly Phe Trp Pro Ala Leu Arg Met Asn Trp Arg Val Trp Thr
145                 150                 155                 160

Pro Leu Gln Phe Ile Asn Ile Asn Tyr Val Pro Leu Lys Phe Arg Val
                165                 170                 175

Leu Phe Ala Asn Leu Ala Ala Leu Phe Trp Tyr Ala Tyr Leu Ala Ser
            180                 185                 190

Leu Gly Lys 
        195



<210> 1881
<211> 268
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1881
Met Pro Asn Val Ala Glu Thr Glu Arg Ser Asn Asp Ser Gly Asn Gly
  1               5                  10                  15

Glu His Lys Ser Glu Arg Lys Ser Pro Glu Glu Asn Leu Gln Gly Ala
             20                  25                  30

Val Lys Ser Phe Cys Thr Ser Ala Ser Gly Ala Pro Leu Gly Pro Lys
         35                  40                  45

Gly Asp Gly His Tyr Pro Trp Ser Cys Pro Val Thr His Thr Arg Glu
     50                  55                  60

Lys Ile Tyr Ala Ile Cys Ser Asp Tyr Ala Phe Leu Asn Gln Ala Thr
 65                  70                  75                  80

Ser Ile Tyr Lys Thr Pro Asn Pro Ser Arg Ser Pro Cys Leu Pro Asp
                 85                  90                  95

Ser Thr Ser Leu Ser Ala Gly Asn Asn Ser Ser Arg Tyr Ile Gly Ile
            100                 105                 110

Pro Thr Ser Thr Ser Glu Ile Ile Tyr Asn Glu Glu Asn Ser Leu Glu
        115                 120                 125

Asn Leu Ser Asn Ser Leu Gly Lys Leu Pro Leu Ala Trp Xaa Ile Asp
    130                 135                 140

Lys Ser Glu Phe Asp Gly Val Thr Thr Asn Ser Lys His Lys Ser Gly
145                 150                 155                 160

Asn Ala Lys Lys Gln Val Ser Lys Arg Lys Thr Ser Asp Lys Lys Gly
                165                 170                 175

Arg Tyr Gln Lys Glu Cys Pro Gln His Ser Pro Leu Glu Asp Ile Lys
            180                 185                 190

Gln Arg Lys Val Leu Asp Leu Arg Arg Trp Tyr Cys Ile Ser Arg Pro
        195                 200                 205

Gln Tyr Lys Thr Ser Cys Gly Ile Ser Ser Leu Ile Ser Cys Trp Asn
    210                 215                 220

Phe Leu Tyr Ser Thr Met Gly Ser Trp Glu Thr Phe His Leu Leu Pro
225                 230                 235                 240

Lys Lys Lys Leu Tyr Ile Phe Trp Ala Phe Asn Leu His Leu Lys Ile
                245                 250                 255

Leu Gly Leu Val Leu Ser Arg Gly Ile Gln His Leu 
            260                 265



<210> 1882
<211> 409
<212> PRT
<213> Homo sapiens

<400> 1882
Met Asn Ser Ser Arg Asp Asn Ser His Pro Phe Val Gly Leu Ala Phe
  1               5                  10                  15

Lys Leu Glu Val Gly Arg Phe Gly Gln Leu Thr Tyr Val Arg Ser Tyr
             20                  25                  30

Gln Gly Glu Leu Lys Lys Gly Asp Thr Ile Tyr Asn Thr Arg Thr Arg
         35                  40                  45

Lys Lys Val Arg Leu Gln Arg Leu Ala Arg Met His Ala Asp Met Met
     50                  55                  60

Glu Asp Val Glu Glu Val Tyr Ala Gly Asp Ile Cys Ala Leu Phe Gly
 65                  70                  75                  80

Ile Asp Cys Ala Ser Gly Asp Thr Phe Thr Asp Lys Ala Asn Ser Gly
                 85                  90                  95

Leu Ser Met Glu Ser Ile His Val Pro Asp Pro Val Ile Ser Ile Ala
            100                 105                 110

Met Lys Pro Ser Asn Lys Asn Asp Leu Glu Lys Phe Ser Lys Gly Ile
        115                 120                 125

Gly Arg Phe Thr Arg Glu Asp Pro Thr Phe Lys Val Tyr Phe Asp Thr
    130                 135                 140

Glu Asn Lys Glu Thr Val Ile Ser Gly Met Gly Glu Leu His Leu Glu
145                 150                 155                 160

Ile Tyr Ala Gln Arg Leu Glu Arg Glu Tyr Gly Cys Pro Cys Ile Thr
                165                 170                 175

Gly Lys Pro Lys Val Ala Phe Arg Glu Thr Ile Thr Ala Pro Val Pro
            180                 185                 190

Phe Asp Phe Thr His Lys Lys Gln Ser Gly Gly Ala Gly Gln Tyr Gly
        195                 200                 205

Lys Val Ile Gly Val Leu Glu Pro Leu Asp Pro Glu Asp Tyr Thr Lys
    210                 215                 220

Leu Glu Phe Ser Asp Glu Thr Phe Gly Ser Asn Ile Pro Lys Gln Phe
225                 230                 235                 240

Val Pro Ala Val Glu Lys Gly Phe Leu Asp Ala Cys Glu Lys Gly Pro
                245                 250                 255

Leu Ser Gly His Lys Leu Ser Gly Leu Arg Phe Val Leu Gln Asp Gly
            260                 265                 270

Ala His His Met Val Asp Ser Asn Glu Ile Ser Phe Ile Arg Ala Gly
        275                 280                 285

Glu Gly Ala Leu Lys Gln Ala Leu Ala Asn Ala Thr Leu Cys Ile Leu
    290                 295                 300

Glu Pro Ile Met Ala Val Glu Val Val Ala Pro Asn Glu Phe Gln Gly
305                 310                 315                 320

Gln Val Ile Ala Gly Ile Asn Arg Arg His Gly Val Ile Thr Gly Gln
                325                 330                 335

Asp Gly Val Glu Asp Tyr Phe Thr Leu Tyr Ala Asp Val Pro Leu Asn
            340                 345                 350

Asp Met Phe Gly Tyr Ser Thr Glu Leu Arg Ser Cys Thr Glu Gly Lys
        355                 360                 365

Gly Glu Tyr Thr Met Glu Tyr Ser Arg Tyr Gln Pro Cys Leu Pro Ser
    370                 375                 380

Thr Gln Glu Asp Val Ile Asn Lys Tyr Leu Glu Ala Thr Gly Gln Leu
385                 390                 395                 400

Pro Val Lys Lys Gly Lys Ala Lys Asn 
                405



<210> 1883
<211> 180
<212> PRT
<213> Homo sapiens

<400> 1883
Met Arg Pro Leu Thr Glu Glu Glu Thr Arg Val Met Phe Glu Lys Ile
  1               5                  10                  15

Ala Lys Tyr Ile Gly Glu Asn Leu Gln Leu Leu Val Asp Arg Pro Asp
             20                  25                  30

Gly Thr Tyr Cys Phe Arg Leu His Asn Asp Arg Val Tyr Tyr Val Ser
         35                  40                  45

Glu Lys Ile Met Lys Leu Ala Ala Asn Ile Ser Gly Asp Lys Leu Val
     50                  55                  60

Ser Leu Gly Thr Cys Phe Gly Lys Phe Thr Lys Thr His Lys Phe Arg
 65                  70                  75                  80

Leu His Val Thr Ala Leu Asp Tyr Leu Ala Pro Tyr Ala Lys Tyr Lys
                 85                  90                  95

Val Trp Ile Lys Pro Gly Ala Glu Gln Ser Phe Leu Tyr Gly Asn His
            100                 105                 110

Val Leu Lys Ser Gly Leu Gly Arg Ile Thr Glu Asn Thr Ser Gln Tyr
        115                 120                 125

Gln Gly Val Val Val Tyr Ser Met Ala Asp Ile Pro Leu Gly Phe Gly
    130                 135                 140

Val Ala Ala Lys Ser Thr Gln Asp Cys Arg Lys Val Asp Pro Met Ala
145                 150                 155                 160

Ile Val Val Phe His Gln Ala Asp Ile Gly Glu Tyr Val Arg His Glu
                165                 170                 175

Glu Thr Leu Thr 
            180



<210> 1884
<211> 211
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (176)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1884
Met Ala Ala Gly Gly Gly Gly Ser Cys Asp Pro Leu Ala Pro Ala Gly
  1               5                  10                  15

Val Pro Cys Ala Phe Ser Pro His Ser Gln Ala Tyr Phe Ala Leu Ala
             20                  25                  30

Ser Thr Asp Gly His Leu Arg Val Trp Glu Thr Ala Asn Asn Arg Leu
         35                  40                  45

His Gln Glu Tyr Val Pro Ser Ala His Leu Ser Gly Thr Cys Thr Cys
     50                  55                  60

Leu Ala Trp Ala Pro Ala Arg Leu Gln Ala Lys Glu Ser Pro Gln Arg
 65                  70                  75                  80

Lys Lys Arg Lys Ser Glu Ala Val Gly Met Ser Asn Gln Thr Asp Leu
                 85                  90                  95

Leu Ala Leu Gly Thr Ala Val Gly Ser Ile Leu Leu Tyr Ser Thr Val
            100                 105                 110

Lys Gly Glu Leu His Ser Lys Leu Ile Ser Gly Gly His Asp Asn Arg
        115                 120                 125

Val Asn Cys Ile Gln Trp His Gln Asp Ser Gly Cys Leu Tyr Xaa Cys
    130                 135                 140

Ser Asp Asp Lys His Ile Val Glu Trp Asn Val Gln Thr Cys Lys Val
145                 150                 155                 160

Lys Cys Lys Trp Lys Gly Asp Asn Ser Lys Cys Xaa Phe Leu Cys Xaa
                165                 170                 175

Thr Gln Met Glu Arg Xaa Cys Phe Gln Leu Val Glu Gln Ser Thr Met
            180                 185                 190

Gly Leu Glu Thr Lys Lys Leu Gln Ala Phe Thr Xaa His Cys Asn Ala
        195                 200                 205

Ser Ser Tyr 
    210



<210> 1885
<211> 198
<212> PRT
<213> Homo sapiens

<400> 1885
Met Gly Arg His Glu Val Gly His Ile Asp Asn Ser Met Lys Ile Pro
  1               5                  10                  15

Leu Asn Asn Gly Ala Gly Cys Arg Phe Glu Gly Gln Phe Ser Ile Asn
             20                  25                  30

Lys Val Pro Gly Asn Phe His Val Ser Thr His Ser Ala Thr Ala Gln
         35                  40                  45

Pro Gln Asn Pro Asp Met Thr His Val Ile His Lys Leu Ser Phe Gly
     50                  55                  60

Asp Thr Leu Gln Val Gln Asn Ile His Gly Ala Phe Asn Ala Leu Gly
 65                  70                  75                  80

Gly Ala Asp Arg Leu Thr Ser Asn Pro Leu Ala Ser His Asp Tyr Ile
                 85                  90                  95

Leu Lys Ile Val Pro Thr Val Tyr Glu Asp Lys Ser Gly Lys Gln Arg
            100                 105                 110

Tyr Ser Tyr Gln Tyr Thr Val Ala Asn Lys Glu Tyr Val Ala Tyr Ser
        115                 120                 125

His Thr Gly Arg Ile Ile Pro Ala Ile Trp Phe Arg Tyr Asp Leu Ser
    130                 135                 140

Pro Ile Thr Val Lys Tyr Thr Glu Arg Arg Gln Pro Leu Tyr Arg Phe
145                 150                 155                 160

Ile Thr Thr Ile Cys Ala Ile Ile Gly Gly Thr Phe Thr Val Ala Gly
                165                 170                 175

Ile Leu Asp Ser Cys Ile Phe Thr Ala Ser Glu Ala Trp Lys Lys Ile
            180                 185                 190

Gln Leu Gly Lys Met His 
        195



<210> 1886
<211> 600
<212> PRT
<213> Homo sapiens

<400> 1886
Met Pro Glu Ile Arg Val Thr Pro Leu Gly Ala Gly Gln Asp Val Gly
  1               5                  10                  15

Arg Ser Cys Ile Leu Val Ser Ile Ala Gly Lys Asn Val Met Leu Asp
             20                  25                  30

Cys Gly Met His Met Gly Phe Asn Asp Asp Arg Arg Phe Pro Asp Phe
         35                  40                  45

Ser Tyr Ile Thr Gln Asn Gly Arg Leu Thr Asp Phe Leu Asp Cys Val
     50                  55                  60

Ile Ile Ser His Phe His Leu Asp His Cys Gly Ala Leu Pro Tyr Phe
 65                  70                  75                  80

Ser Glu Met Val Gly Tyr Asp Gly Pro Ile Tyr Met Thr His Pro Thr
                 85                  90                  95

Gln Ala Ile Cys Pro Ile Leu Leu Glu Asp Tyr Arg Lys Ile Ala Val
            100                 105                 110

Asp Lys Lys Gly Glu Ala Asn Phe Phe Thr Ser Gln Met Ile Lys Asp
        115                 120                 125

Cys Met Lys Lys Val Val Ala Val His Leu His Gln Thr Val Gln Val
    130                 135                 140

Asp Asp Glu Leu Glu Ile Lys Ala Tyr Tyr Ala Gly His Val Leu Gly
145                 150                 155                 160

Ala Ala Met Phe Gln Ile Lys Val Gly Ser Glu Ser Val Val Tyr Thr
                165                 170                 175

Gly Asp Tyr Asn Met Thr Pro Asp Arg His Leu Gly Ala Ala Trp Ile
            180                 185                 190

Asp Lys Cys Arg Pro Asn Leu Leu Ile Thr Glu Ser Thr Tyr Ala Thr
        195                 200                 205

Thr Ile Arg Asp Ser Lys Arg Cys Arg Glu Arg Asp Phe Leu Lys Lys
    210                 215                 220

Val His Glu Thr Val Glu Arg Gly Gly Lys Val Leu Ile Pro Val Phe
225                 230                 235                 240

Ala Leu Gly Arg Ala Gln Glu Leu Cys Ile Leu Leu Glu Thr Phe Trp
                245                 250                 255

Glu Arg Met Asn Leu Lys Val Pro Ile Tyr Phe Ser Thr Gly Leu Thr
            260                 265                 270

Glu Lys Ala Asn His Tyr Tyr Lys Leu Phe Ile Pro Trp Thr Asn Gln
        275                 280                 285

Lys Ile Arg Lys Thr Phe Val Gln Arg Asn Met Phe Glu Phe Lys His
    290                 295                 300

Ile Lys Ala Phe Asp Arg Ala Phe Ala Asp Asn Pro Gly Pro Met Val
305                 310                 315                 320

Val Phe Ala Thr Pro Gly Met Leu His Ala Gly Gln Ser Leu Gln Ile
                325                 330                 335

Phe Arg Lys Trp Ala Gly Asn Glu Lys Asn Met Val Ile Met Pro Gly
            340                 345                 350

Tyr Cys Val Gln Gly Thr Val Gly His Lys Ile Leu Ser Gly Gln Arg
        355                 360                 365

Lys Leu Glu Met Glu Gly Arg Gln Val Leu Glu Val Lys Met Gln Val
    370                 375                 380

Glu Tyr Met Ser Phe Ser Ala His Ala Asp Ala Lys Gly Ile Met Gln
385                 390                 395                 400

Leu Val Gly Gln Ala Glu Pro Glu Ser Val Leu Leu Val His Gly Glu
                405                 410                 415

Ala Lys Lys Met Glu Phe Leu Lys Gln Lys Ile Glu Gln Glu Leu Arg
            420                 425                 430

Val Asn Cys Tyr Met Pro Ala Asn Gly Glu Thr Val Thr Leu Pro Thr
        435                 440                 445

Ser Pro Ser Ile Pro Val Gly Ile Ser Leu Gly Leu Leu Lys Arg Glu
    450                 455                 460

Met Ala Gln Gly Leu Leu Pro Glu Ala Lys Lys Pro Arg Leu Leu His
465                 470                 475                 480

Gly Thr Leu Ile Met Lys Asp Ser Asn Phe Arg Leu Val Ser Ser Glu
                485                 490                 495

Gln Ala Leu Lys Glu Leu Gly Leu Ala Glu His Gln Leu Arg Phe Thr
            500                 505                 510

Cys Arg Val His Leu His Asp Thr Arg Lys Glu Gln Glu Thr Ala Leu
        515                 520                 525

Arg Val Tyr Ser His Leu Lys Ser Val Leu Lys Asp His Cys Val Gln
    530                 535                 540

His Leu Pro Asp Gly Ser Val Thr Val Glu Ser Val Leu Leu Gln Ala
545                 550                 555                 560

Ala Ala Pro Ser Glu Asp Pro Gly Thr Lys Val Leu Leu Val Ser Trp
                565                 570                 575

Thr Tyr Gln Asp Glu Glu Leu Gly Ser Phe Leu Thr Ser Leu Leu Lys
            580                 585                 590

Lys Gly Leu Pro Gln Ala Pro Ser 
        595                 600



<210> 1887
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1887
Met Val Phe Ile Gly Ile Ala Phe Asn Phe Ile Leu Asp Arg Lys Val
  1               5                  10                  15

Pro Val Tyr Val Glu Asn Phe Leu Asp Gly Leu Gly Asn Ser Phe Ser
             20                  25                  30

Gly Ser Ala Leu Phe Tyr Leu Gly Leu Thr Met Val Gly Lys Ile Lys
         35                  40                  45

Arg Leu Lys Lys Ser Ala Phe Val Val Leu Ile Leu Leu Ile Thr Ala
     50                  55                  60

Lys Leu Leu Val Leu Pro Leu Leu Cys Arg Glu Met Val Glu Leu Leu
 65                  70                  75                  80

Asp Lys Gly Asp Ser Val Val Asn His Thr Ser Leu Ser Asn Tyr Ala
                 85                  90                  95

Phe Leu Tyr Gly Val Phe Pro Val Ala Pro Gly Xaa Ala Thr Leu Gln
            100                 105                 110

His Asn Ser Thr Trp Lys 
        115



<210> 1888
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (176)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1888
Met Ala Ala Pro Arg Gln Ile Pro Ser His Ile Val Arg Leu Lys Pro
  1               5                  10                  15

Ser Cys Ser Thr Asp Ser Ser Phe Thr Arg Thr Pro Val Pro Thr Val
             20                  25                  30

Ser Leu Ala Ser Arg Glu Leu Pro Val Ser Ser Trp Gln Val Thr Glu
         35                  40                  45

Pro Ser Ser Lys Asn Leu Trp Glu Gln Ile Cys Lys Glu Tyr Glu Ala
     50                  55                  60

Glu Gln Pro Pro Phe Pro Glu Gly Tyr Lys Val Lys Gln Glu Pro Val
 65                  70                  75                  80

Ile Thr Val Ala Pro Val Glu Glu Met Leu Phe His Gly Phe Ser Ala
                 85                  90                  95

Glu His Tyr Phe Pro Val Ser His Phe Thr Met Ile Ser Arg Thr Pro
            100                 105                 110

Cys Pro Gln Asp Lys Ser Glu Thr Ile Asn Pro Lys Thr Cys Ser Pro
        115                 120                 125

Lys Glu Tyr Leu Glu Thr Phe Ile Phe Pro Val Leu Leu Pro Gly Met
    130                 135                 140

Ala Ser Leu Leu His Gln Ala Lys Lys Glu Lys Xaa Phe Glu Arg Lys
145                 150                 155                 160

Arg Thr Xaa Phe Ile Xaa Xaa Asp Phe Xaa Leu Asn Gly Leu Tyr Xaa
                165                 170                 175






<210> 1889
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1889
Met Phe Leu Ala Asp Val Val Asp Phe Ile Ile Ile Ile Phe Gly Phe
  1               5                  10                  15

Trp Ala Phe Gly Lys His Ser Ala Ala Thr Asp Ile Thr Ser Ser Leu
             20                  25                  30

Ser Asp Asp Gln Val Pro Glu Ala Phe Leu Val Met Leu Leu Ile Gln
         35                  40                  45

Phe Ser Thr Met Val Val Asp Arg Ala Leu Tyr Leu Arg Lys Thr Val
     50                  55                  60

Leu Gly Lys Leu Ala Phe Gln Val Ala Leu Val Leu Ala Ile His Leu
 65                  70                  75                  80

Trp Met Phe Phe Ile Leu Pro Ala Val Thr Glu Arg Met Xaa Asn Gln
                 85                  90                  95

Asn Val Val Ala Xaa Leu Trp Tyr Xaa Val Lys Cys Ile Tyr Xaa Ala
            100                 105                 110

Cys Pro Pro Thr Asp Pro Leu Arg Val Pro His Arg Ile Leu Gly Asn
        115                 120                 125

Phe Leu Thr Lys Lys Ser Ile 
    130                 135



<210> 1890
<211> 154
<212> PRT
<213> Homo sapiens

<400> 1890
Met Val Leu Gly Ile Gln Leu Glu Glu Gly Tyr Arg Thr Tyr His Met
  1               5                  10                  15

Asp Glu Tyr Asp Glu Asp Lys Asn Pro Ser Gly Ile Ile Asn Leu Gly
             20                  25                  30

Thr Ser Glu Asn Lys Leu Cys Phe Asp Leu Leu Ser Trp Arg Leu Ser
         35                  40                  45

Gln Arg Asp Met Gln Arg Val Glu Pro Ser Leu Leu Gln Tyr Ala Asp
     50                  55                  60

Trp Arg Gly His Leu Phe Leu Arg Glu Lys Val Ala Lys Phe Leu Ser
 65                  70                  75                  80

Phe Tyr Cys Lys Ser Pro Val Pro Leu Arg Pro Glu Asn Val Val Val
                 85                  90                  95

Leu Asn Gly Gly Ala Ser Leu Phe Ser Ala Leu Ala Thr Val Leu Cys
            100                 105                 110

Glu Ala Gly Glu Ala Phe Leu Ile Pro Thr Pro Tyr Tyr Gly Ala Ile
        115                 120                 125

Thr Gln His Val Cys Leu Tyr Gly Asn Ile Arg Leu Ala Tyr Val Tyr
    130                 135                 140

Leu Asp Ser Glu Val Arg Val Leu Thr Ser 
145                 150



<210> 1891
<211> 181
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1891
Met Ala Pro Ala Leu Leu Leu Ile Pro Ala Ala Leu Ala Ser Phe Ile
  1               5                  10                  15

Leu Ala Phe Gly Thr Gly Val Glu Phe Val Arg Phe Thr Ser Leu Arg
             20                  25                  30

Pro Leu Leu Gly Gly Ile Pro Glu Ser Gly Gly Pro Asp Ala Arg Gln
         35                  40                  45

Gly Trp Leu Ala Ala Leu Gln Asp Arg Ser Ile Leu Ala Pro Leu Ala
     50                  55                  60

Trp Asp Leu Gly Leu Leu Leu Leu Phe Val Gly Gln His Ser Leu Met
 65                  70                  75                  80

Ala Ala Glu Arg Val Lys Ala Trp Thr Ser Arg Tyr Phe Gly Val Leu
                 85                  90                  95

Gln Arg Ser Leu Tyr Val Xaa Cys Thr Ala Leu Ala Leu Gln Leu Val
            100                 105                 110

Met Arg Tyr Trp Glu Pro Ile Pro Lys Gly Pro Val Leu Trp Glu Ala
        115                 120                 125

Arg Ala Glu His Gly Xaa Leu Gly Ala Ala Pro Leu Leu Cys Ala Pro
    130                 135                 140

Cys His Leu Leu Leu Leu Ile Phe Ser Ile Leu Leu Ala Leu Thr Met
145                 150                 155                 160

Xaa Ser Ser Trp Ala Ser Asn Arg Tyr Thr Thr Met Cys Trp Gly Trp
                165                 170                 175

Ala Ser Leu Trp Pro 
            180



<210> 1892
<211> 134
<212> PRT
<213> Homo sapiens

<400> 1892
Met Leu Leu Gly His Gln Ala Met Gly Ala Val Asp Gln Pro His Ala
  1               5                  10                  15

Leu Ala Pro His Ser Leu Leu Thr Gly Phe Thr Gly Ile Gly Ser Gly
             20                  25                  30

His Arg Asp Phe Ser Gln Ser Gln Gln Pro Thr Gln Leu Pro His Thr
         35                  40                  45

Val Ala Ser Glu Asn Phe Gln Arg Gly Ile Leu Phe Val Val Gly Leu
     50                  55                  60

Ser Gly Phe Ser Ser Phe Ser Met Val Ile Phe Lys Ser Leu Phe Leu
 65                  70                  75                  80

Asn Ala Lys Ile Asn Val Leu Ile Asn Ala Ser Asn Phe Arg Ala Gln
                 85                  90                  95

Cys Ser His Val Gln Phe Pro Leu Phe Lys Ile Asn Lys Cys Val Gly
            100                 105                 110

Ser Phe Gly Val Trp Gly Asp Ile Met Val Thr Gly Asn Glu Ser Leu
        115                 120                 125

Ile Phe His Lys Cys Ala 
    130



<210> 1893
<211> 124
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1893
Met Ser Arg Arg Leu Ser Gln Met Leu Leu Met Phe Leu Leu Ala Thr
  1               5                  10                  15

Cys Leu Leu Ala Ile Ile Phe Val Pro Gln Glu Met Gln Thr Leu Arg
             20                  25                  30

Val Val Leu Ala Thr Leu Gly Val Gly Ala Ala Ser Leu Gly Ile Thr
         35                  40                  45

Cys Ser Thr Ala Gln Glu Asn Glu Leu Ile Pro Ser Ile Ile Arg Gly
     50                  55                  60

Arg Ala Thr Gly Asn His Trp Glu Thr Leu Leu Ile Leu Gly Glu Pro
 65                  70                  75                  80

Trp Xaa Pro Ser Xaa Met Ile Leu Ser Ile Tyr Xaa Arg Pro Leu Ala
                 85                  90                  95

Leu Gly Ser Ser Met Gly Val Phe Ala Ile Leu Ser Gly Leu Val Val
            100                 105                 110

Leu Leu Leu Pro Glu Thr Arg Glu Pro Ala Ser Ser 
        115                 120



<210> 1894
<211> 153
<212> PRT
<213> Homo sapiens

<400> 1894
Met Pro Glu Cys Gln His Val Trp His Trp Ser Gly Leu Gln Leu Ala
  1               5                  10                  15

Lys Gly Cys Leu Leu Asn His Ser Ser Ile Val Pro Val Leu Gln Asp
             20                  25                  30

Ile Ile Lys Asp Cys Tyr Gly Ile Thr Lys Cys Asp Arg His Val Gly
         35                  40                  45

Lys Ile Tyr Ser Lys Cys Ser Ser Phe Leu Asp Tyr Val Arg Arg Ser
     50                  55                  60

Leu Lys Lys Leu Gly Leu Asp Glu Ser Lys Leu Pro Glu Lys Ile Ile
 65                  70                  75                  80

Met Asn Tyr Tyr Glu Lys Tyr Lys Pro Arg Met Asn Glu Leu Glu Ala
                 85                  90                  95

Phe Asn Met Leu Lys Val Val Leu Ala Pro Cys Ile Glu Thr Leu Ile
            100                 105                 110

Leu Leu Asp Arg Leu Cys Tyr Leu Lys Glu Gln Glu Asp Ile Ala Trp
        115                 120                 125

Ser Ala Leu Val Lys Leu Phe Asp Pro Val Lys Ser Pro Arg Cys Tyr
    130                 135                 140

Ala Val Ile Ala Leu Lys Lys Gln Gln 
145                 150



<210> 1895
<211> 165
<212> PRT
<213> Homo sapiens

<400> 1895
Met Ser Tyr Ser Phe His Asp Val Gly Tyr Tyr Leu Pro Leu Phe Phe
  1               5                  10                  15

Ser Phe Pro Phe Phe Phe Phe Leu Asp Arg Leu Trp Leu Cys Gln Pro
             20                  25                  30

Gly Trp Ser Ala Val Val Gln Pro Gln Leu Thr Thr Asn Ser Ala Ser
         35                  40                  45

Leu Ala Gln Gly Ile His Phe Arg Leu Pro Ser Ser Trp Asp Cys Arg
     50                  55                  60

His Thr Pro Pro His Leu Val Asn Phe Phe Pro Tyr Phe Val Glu Thr
 65                  70                  75                  80

Gly Ser His Phe Val Val Gln Ala Gly Leu Glu Phe Leu Ser Ser Ser
                 85                  90                  95

Asn Leu Pro Thr Leu Ala Ser Gln Ser Ala Gly Ile Thr Gly Val Ser
            100                 105                 110

His Cys Ala Trp Leu Pro Ile Phe Phe Leu Ile Asn Pro Thr Ser Ala
        115                 120                 125

Glu Leu Lys Glu Ser Val Lys Tyr Lys Asn Glu Phe Ile Met Gln Ile
    130                 135                 140

Cys Ser Tyr Arg Val Cys Ser Phe Gly Leu Val Ile Arg Glu Tyr Val
145                 150                 155                 160

Leu Val Leu Lys Lys 
                165



<210> 1896
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1896
Met Leu His Ile Leu Asn Phe Ser Cys Ala Val Trp Leu Gly Ile Cys
  1               5                  10                  15

Leu Ala Phe Cys Met Phe Leu Tyr Lys Arg Glu Leu Ser Tyr Leu Thr
             20                  25                  30

Glu Asn Arg Tyr Met Glu Val Asp Ser Leu Pro Val Glu Pro Ala Cys
         35                  40                  45

Phe Phe Val Phe Phe Cys Cys Cys Cys Phe Phe Leu Ser Tyr Ile Cys
     50                  55                  60

Phe Tyr Phe Leu Lys Lys Lys Arg Lys Xaa Ser Pro Leu Leu Glu Thr
 65                  70                  75                  80

Thr Ser Val Ile Leu Gly Ala Leu Ser Leu Gln Ile Gly Lys Pro Ser
                 85                  90                  95

Tyr Thr Lys Leu Phe Thr Phe Phe Ile Tyr Asp Ser Thr Asn Arg Arg
            100                 105                 110

Asp 




<210> 1897
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (6)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1897
Met Leu Leu Xaa Leu Xaa His Tyr Arg Xaa Glu Ile Val Lys His Xaa
  1               5                  10                  15

Gly His Leu Val Glu Xaa Leu Cys Arg Arg Val Ile Arg Ser Val Thr
             20                  25                  30

Leu Gln Val Leu Leu Arg Phe Val Asp Gln Arg Ile Gly Asn Phe Xaa
         35                  40                  45

Val Ser Ile Phe Ser Ser Pro Leu Arg Ile Ala Ser Phe Asn Ala Ser
     50                  55                  60

Thr Arg Ser Arg Leu Ile Ser Leu Leu Pro Gly Cys Ile Ser Phe Ala
 65                  70                  75                  80

Cys Ala Ser Leu Asn Val Thr Leu Val Leu Val Glu Ala Val Val Phe
                 85                  90                  95

Ala Ala Arg Leu Phe Val Thr Gly Ala Ser Val Val Ser Arg Gly 
            100                 105                 110



<210> 1898
<211> 206
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (44)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1898
Met Arg Ile Ile Glu Ser Asn Ser Ser Lys Ile Gln Ser Gln Ile Asp
  1               5                  10                  15

His Ile Lys Gln Cys Arg Ala Glu Tyr Asp Thr Lys Glu Val Lys Tyr
             20                  25                  30

Trp Thr Phe Xaa Lys Asp Pro Ser Lys Pro Ile Xaa Gly Met Thr Leu
         35                  40                  45

Gln Glu Xaa Met Asn Leu Asp Ala Leu Thr Lys Tyr Met Lys His Leu
     50                  55                  60

Glu Asp Lys Tyr Ala Glu Ile Lys Gln Ala Met Leu Ile Lys Tyr Val
 65                  70                  75                  80

Pro Ala Gln Arg Lys Ala Asp Leu Asp Glu Glu Met Ile Val Leu Leu
                 85                  90                  95

Lys Arg Arg Asp Val Ala Glu Asn Leu Asn Lys Lys Leu Gln Phe Trp
            100                 105                 110

Phe Asn Glu Leu Ile Ser Leu Gly Glu Tyr Glu Lys Ala Ala Cys Tyr
        115                 120                 125

Ala Ala Asn Ser Pro Arg Arg Ile Leu Arg Asn Ile Gly Thr Met Asn
    130                 135                 140

Thr Phe Lys Ala Val Gly Lys Ile Arg Gly Lys Pro Leu Pro Leu Leu
145                 150                 155                 160

Leu Phe Phe Glu Ala Leu Phe Ile Thr Ser His Ala Phe Pro Cys Pro
                165                 170                 175

Val Asp Ala Ala Leu Thr Leu Glu Gly Ile Lys Cys Gly Leu Ser Glu
            180                 185                 190

Lys Arg Leu Asp Leu Val Thr Asn Trp Val Thr Gln Glu Arg 
        195                 200                 205



<210> 1899
<211> 122
<212> PRT
<213> Homo sapiens

<400> 1899
Met Thr Ser His Glu Pro Pro Val Tyr Met Asp Glu Asp Asp Asp Arg
  1               5                  10                  15

Ser Cys Phe His Ser His Met Asn Thr Ala Val Glu Asp Ala Ser Asp
             20                  25                  30

Asp Glu Ser Ile Pro Ile Met Tyr Arg Asn Leu Pro Glu Tyr Lys Glu
         35                  40                  45

Leu Leu Gln Phe Lys Lys Leu Lys Lys Gln Lys Leu Gln Gln Met Gln
     50                  55                  60

Ala Glu Ser Gly Phe Val Gln His Val Gly Phe Lys Cys Asp Asn Cys
 65                  70                  75                  80

Gly Ile Glu Pro Ile Gln Gly Val Arg Trp His Cys Arg Ile Val Leu
                 85                  90                  95

Gln Lys Cys Leu Trp Ile Ser Val Ile Leu Val Gln Thr Val Tyr Met
            100                 105                 110

Lys Gln Ile Phe Thr Arg Lys Ile Thr Asn 
        115                 120



<210> 1900
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1900
Met Asp Asp Phe Leu Phe Ser Val Ser Ile Leu Ser Gly Ile Leu Cys
  1               5                  10                  15

Ser Ile Leu Ala Val Leu Lys Phe Met Leu Gly Lys Val Leu Thr Ser
             20                  25                  30

Arg Ala Leu Ile Thr Asp Gly Phe Asn Ser Leu Val Gly Gly Val Met
         35                  40                  45

Gly Phe Ser Ile Leu Leu Ser Ala Glu Val Phe Lys His Asp Ser Ala
     50                  55                  60

Val Trp Tyr Leu Asp Gly Ser Ile Gly Val Leu Ile Gly Leu Thr Ile
 65                  70                  75                  80

Phe Ala Tyr Gly Val Lys Leu Leu Ile Asp Xaa Val Pro Arg Val Arg
                 85                  90                  95

Gln Thr Arg His Tyr Glu Met Phe Glu 
            100                 105



<210> 1901
<211> 132
<212> PRT
<213> Homo sapiens

<400> 1901
Met Thr Leu Ala Ala Arg Ala Met Arg Asn Asn Phe Arg His Tyr Phe
  1               5                  10                  15

Ile Glu Pro Ser Gln Leu Lys Leu Phe Tyr Asp Val Ile Thr Trp Ile
             20                  25                  30

Val Thr Gln Val Ala Ile Ser Tyr Thr Val Val Pro Phe Val Leu Leu
         35                  40                  45

Ser Ile Lys Pro Ser Leu Thr Phe Tyr Ser Ser Trp Tyr Tyr Cys Leu
     50                  55                  60

His Ile Leu Gly Ile Leu Val Leu Leu Leu Leu Pro Val Lys Lys Thr
 65                  70                  75                  80

Gln Arg Arg Lys Asn Thr His Glu Asn Ile Gln Leu Ser Gln Ser Lys
                 85                  90                  95

Lys Phe Asp Glu Gly Glu Asn Ser Leu Gly Gln Asn Ser Phe Ser Thr
            100                 105                 110

Thr Asn Asn Val Cys Asn Gln Asn Gln Glu Ile Ala Ser Arg His Ser
        115                 120                 125

Ser Leu Lys Gln 
    130



<210> 1902
<211> 272
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (243)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (249)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (256)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1902
Met Gln Ala Ala Arg Val Asp Tyr Ile Ala Pro Trp Trp Val Val Trp
  1               5                  10                  15

Leu His Ser Val Pro His Val Gly Leu Arg Leu Gln Pro Val Asn Ser
             20                  25                  30

Thr Phe Ser Pro Gly Asp Glu Ser Tyr Gln Glu Ser Leu Leu Phe Leu
         35                  40                  45

Gly Leu Val Ala Ala Val Cys Leu Gly Leu Asn Leu Ile Phe Leu Val
     50                  55                  60

Ala Tyr Leu Val Cys Ala Cys His Cys Arg Arg Asp Asp Ala Val Gln
 65                  70                  75                  80

Thr Lys Gln His His Ser Cys Cys Ile Xaa Trp Thr Ala Val Val Ala
                 85                  90                  95

Gly Leu Ile Cys Cys Ala Ala Val Gly Val Gly Phe Tyr Gly Asn Ser
            100                 105                 110

Glu Thr Asn Asp Gly Ala Tyr Gln Leu Met Tyr Ser Leu Asp Asp Ala
        115                 120                 125

Asn Xaa Thr Phe Ser Gly Ile Asp Ala Leu Val Ser Gly Thr Thr Gln
    130                 135                 140

Lys Met Lys Val Asp Leu Glu Gln His Leu Ala Arg Leu Ser Glu Ile
145                 150                 155                 160

Phe Ala Ala Arg Gly Asp Tyr Leu Gln Thr Leu Lys Phe Ile Gln Gln
                165                 170                 175

Met Ala Gly Ser Val Val Val Gln Leu Ser Gly Leu Pro Val Trp Arg
            180                 185                 190

Glu Val Thr Met Glu Leu Thr Lys Leu Ser Asp Gln Thr Gly Tyr Val
        195                 200                 205

Glu Tyr Tyr Arg Trp Leu Ser Tyr Leu Leu Leu Phe Ile Leu Asp Leu
    210                 215                 220

Val Ile Cys Leu Ile Ala Cys Leu Gly Leu Ala Lys Arg Ser Lys Cys
225                 230                 235                 240

Leu Leu Xaa Ser Met Leu Cys Cys Xaa Ala Leu Ser Leu Leu Leu Xaa
                245                 250                 255

Trp Ala Ser Leu Ala Ala Asp Gly Ala Ala Ala Val Gly Thr Ser Asp
            260                 265                 270






<210> 1903
<211> 199
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1903
Met Gly Gly Phe Phe Asn Ser Gly Cys Ser Gln Cys Gln Ile Ser Ser
  1               5                  10                  15

Phe Tyr Leu Val Asn Asp Ile Tyr Glu Leu Asp Thr Ser Gly Leu Glu
             20                  25                  30

Asp Thr Met Glu Ile Gln Glu Arg Ile Glu Asn Ser Phe Lys Ser Leu
         35                  40                  45

Leu Asp Gln Leu Lys Asp Val Phe Ser Lys Cys Lys Gly Asp Leu Leu
     50                  55                  60

Glu Val Lys Asp Gly Asn Leu Lys Thr His Pro Thr Leu Leu Glu Asn
 65                  70                  75                  80

Leu Val Phe Phe Val Glu Thr Ile Ser Val Ile Leu Trp Val Ser Ser
                 85                  90                  95

Tyr Cys Glu Ser Val Leu Arg Pro Tyr Lys Leu Asn Leu Gln Lys Lys
            100                 105                 110

Lys Lys Lys Lys Lys Glu Thr Ser Ile Ile Met Pro Pro Val Phe Thr
        115                 120                 125

Ser Phe Gln Asp Tyr Val Thr Gly Leu Gln Thr Leu Ile Ser Asn Val
    130                 135                 140

Val Asp His Ile Lys Gly Leu Glu Thr His Leu Ile Ala Leu Lys Leu
145                 150                 155                 160

Glu Glu Leu Ile Leu Glu Asp Thr Ser Leu Ser Pro Glu Glu Arg Lys
                165                 170                 175

Phe Ser Lys Thr Val Gln Gly Lys Val Gln Xaa Val Ile Cys Thr His
            180                 185                 190

Phe Trp Lys Trp Gly Ser Cys 
        195



<210> 1904
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1904
Met Leu Gln Ala Thr Ala Glu Ala Asn Asn Leu Ala Ala Ala Ala Ser
  1               5                  10                  15

Ala Lys Asp Ile Tyr Tyr Asn Asn Met Glu Glu Val Cys Gly Gly Glu
             20                  25                  30

Lys Pro Tyr Leu Ser Pro Asp Ile Leu Glu Glu Lys His Cys Glu Phe
         35                  40                  45

Lys Gln Leu Ala Leu Asp His Phe Lys Lys Thr Lys Lys Met Gly Gly
     50                  55                  60

Lys Asp Phe Ser Phe Arg Tyr Gln Gln Glu Leu Glu Glu Glu Ile Lys
 65                  70                  75                  80

Glu Leu Tyr Glu Asn Phe Cys Lys His Asn Gly Ser Lys Asn Val Phe
                 85                  90                  95

Ser Thr Phe Arg Thr Pro Ala Val Leu Phe Thr Gly Ile Val Ala Leu
            100                 105                 110

Tyr Ile Ala Ser Gly Leu Thr Gly Phe Ile Gly Leu Glu Val Val Ala
        115                 120                 125

Gln Leu Phe Asn Cys Met Val Gly Leu Leu Leu Ile Ala Leu Leu Thr
    130                 135                 140

Trp Gly Tyr Ile Arg Tyr Ser Gly Gln Tyr Arg Glu Leu Gly Gly Leu
145                 150                 155                 160

Leu Ile Leu Val Pro His Met Cys Trp Ser Arg Leu Leu Leu Ile Ser
                165                 170                 175

Xaa Ile Pro Leu Arg Pro Leu 
            180



<210> 1905
<211> 262
<212> PRT
<213> Homo sapiens

<400> 1905
Met Val Thr Leu Val Pro Tyr Trp Met Val Tyr Phe Gln Met Gln Ser
  1               5                  10                  15

Thr Tyr Val Leu Gln Gly Leu His Leu His Ile Pro Asn Ile Phe Pro
             20                  25                  30

Ala Asn Pro Ala Asn Ile Ser Val Ala Leu Arg Ala Gln Gly Ser Ser
         35                  40                  45

Tyr Thr Ile Pro Glu Ala Trp Leu Leu Leu Ala Asn Val Val Val Val
     50                  55                  60

Leu Ile Leu Val Pro Leu Lys Asp Arg Leu Ile Asp Pro Leu Leu Leu
 65                  70                  75                  80

Arg Cys Lys Leu Leu Pro Ser Ala Leu Gln Lys Met Ala Leu Gly Met
                 85                  90                  95

Phe Phe Gly Phe Thr Ser Val Ile Val Ala Gly Val Leu Glu Met Glu
            100                 105                 110

Arg Leu His Tyr Ile His His Asn Glu Thr Val Ser Gln Gln Ile Gly
        115                 120                 125

Glu Val Leu Tyr Asn Ala Ala Pro Leu Ser Ile Trp Trp Gln Ile Pro
    130                 135                 140

Gln Tyr Leu Leu Ile Gly Ile Ser Glu Ile Phe Ala Ser Ile Pro Gly
145                 150                 155                 160

Leu Glu Phe Ala Tyr Ser Glu Ala Pro Arg Ser Met Gln Gly Ala Ile
                165                 170                 175

Met Gly Ile Phe Phe Cys Leu Ser Gly Val Gly Ser Leu Leu Gly Ser
            180                 185                 190

Ser Leu Val Ala Leu Leu Ser Leu Pro Gly Gly Trp Leu His Cys Pro
        195                 200                 205

Lys Asp Phe Gly Asn Ile Asn Asn Cys Arg Met Asp Leu Tyr Phe Phe
    210                 215                 220

Leu Leu Ala Gly Ile Gln Ala Val Thr Ala Leu Leu Phe Val Trp Ile
225                 230                 235                 240

Ala Gly Arg Tyr Glu Arg Ala Ser Gln Gly Pro Ala Ser His Ser Arg
                245                 250                 255

Phe Ser Arg Asp Arg Gly 
            260



<210> 1906
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (138)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1906
Met Lys Lys Cys Glu Asp Gly Ser Trp Lys Arg Leu Pro Ser Tyr Lys
  1               5                  10                  15

Arg Thr Pro Thr Glu Trp Ile Gln Asp Phe Lys Thr His Phe Leu Asp
             20                  25                  30

Pro Lys Leu Met Lys Glu Glu Gln Met Ser Gln Ala Gln Leu Phe Thr
         35                  40                  45

Arg Ser Phe Asp Asp Gly Leu Gly Phe Glu Tyr Val Met Phe Tyr Asn
     50                  55                  60

Asp Ile Glu Lys Arg Met Val Cys Leu Phe Gln Gly Gly Pro Tyr Leu
 65                  70                  75                  80

Glu Gly Pro Pro Gly Phe Ile His Gly Gly Ala Ile Ala Thr Met Ile
                 85                  90                  95

Asp Ala Thr Val Gly Met Cys Ala Met Met Ala Gly Gly Ile Val Met
            100                 105                 110

Thr Ala Asn Leu Asn Ile Asn Tyr Lys Arg Pro Ile Pro Leu Cys Ser
        115                 120                 125

Val Val Met Ile Asn Ser Gln Leu Xaa Xaa Ser 
    130                 135



<210> 1907
<211> 421
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (248)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1907
Met Pro Val Ser Cys Ser Leu Ser Arg Gly Leu Gln Val Leu Leu Thr
  1               5                  10                  15

Pro Val Leu Ala Asn Ile Leu Glu Ala Asp Gln Glu Lys Cys Trp Gly
             20                  25                  30

Phe Asp Gln Phe Phe Ala Glu Thr Ser Asp Ile Leu Xaa Arg Met Val
         35                  40                  45

Ile His Val Phe Ser Leu Gln Gln Met Thr Ala His Lys Ile Tyr Ile
     50                  55                  60

His Ser Tyr Asn Thr Ala Thr Ile Phe His Glu Leu Val Tyr Lys Gln
 65                  70                  75                  80

Thr Lys Ile Ile Ser Ser Asn Gln Glu Leu Ile Tyr Glu Gly Arg Arg
                 85                  90                  95

Leu Val Leu Glu Pro Gly Arg Leu Ala Gln His Phe Pro Lys Thr Thr
            100                 105                 110

Glu Glu Asn Pro Ile Phe Val Val Ser Arg Glu Pro Leu Asn Thr Ile
        115                 120                 125

Gly Leu Ile Tyr Glu Lys Ile Ser Leu Pro Lys Val His Pro Arg Tyr
    130                 135                 140

Asp Leu Asp Gly Asp Ala Ser Met Ala Lys Ala Ile Thr Gly Val Val
145                 150                 155                 160

Cys Tyr Ala Cys Arg Ile Ala Ser Thr Leu Leu Leu Tyr Gln Glu Leu
                165                 170                 175

Met Arg Lys Gly Ile Arg Trp Leu Ile Glu Leu Ile Lys Asp Asp Tyr
            180                 185                 190

Asn Glu Thr Val His Lys Lys Thr Glu Val Val Ile Thr Leu Asp Phe
        195                 200                 205

Cys Ile Arg Asn Ile Glu Lys Thr Val Lys Val Tyr Glu Lys Leu Met
    210                 215                 220

Lys Ile Asn Leu Glu Ala Ala Glu Leu Gly Glu Ile Ser Asp Ile His
225                 230                 235                 240

Thr Lys Leu Leu Arg Leu Ser Xaa Ser Gln Gly Thr Ile Glu Thr Ser
                245                 250                 255

Leu Gln Asp Ile Asp Ser Arg Leu Ser Pro Gly Gly Ser Leu Ala Asp
            260                 265                 270

Ala Trp Ala His Gln Glu Gly Thr His Pro Lys Asp Arg Asn Val Glu
        275                 280                 285

Lys Leu Gln Val Leu Leu Asn Cys Met Thr Glu Ile Tyr Tyr Gln Phe
    290                 295                 300

Lys Lys Asp Lys Ala Glu Arg Arg Leu Ala Tyr Asn Glu Glu Gln Ile
305                 310                 315                 320

His Lys Phe Asp Lys Gln Lys Leu Tyr Tyr His Ala Thr Lys Ala Met
                325                 330                 335

Thr His Phe Thr Asp Glu Cys Val Lys Lys Tyr Glu Ala Phe Leu Asn
            340                 345                 350

Lys Ser Glu Glu Trp Ile Arg Lys Met Leu His Leu Arg Lys Gln Leu
        355                 360                 365

Leu Ser Leu Thr Asn Gln Cys Phe Asp Ile Glu Glu Glu Val Ser Lys
    370                 375                 380

Tyr Gln Glu Tyr Thr Asn Glu Leu Gln Glu Thr Leu Pro Gln Lys Met
385                 390                 395                 400

Phe Thr Ala Ser Ser Gly Asn Gln Thr Tyr His Gly Pro Gln Phe Ile
                405                 410                 415

Gln Val Leu Thr His 
            420



<210> 1908
<211> 127
<212> PRT
<213> Homo sapiens

<400> 1908
Met Leu Ser Tyr Leu Val Gly Arg Pro Val Val Tyr Lys Tyr Leu Thr
  1               5                  10                  15

Glu Lys Ala Val Lys Trp Ser Gln Gln Val Glu Arg His Arg Glu His
             20                  25                  30

Leu Ile Asn Tyr Ile Ile Phe Leu Arg Ile Thr Pro Phe Leu Pro Asn
         35                  40                  45

Trp Phe Ile Asn Ile Thr Ser Pro Val Ile Asn Val Pro Leu Lys Val
     50                  55                  60

Phe Phe Ile Gly Thr Phe Leu Gly Val Ala Pro Pro Ser Phe Val Ala
 65                  70                  75                  80

Ile Lys Ala Gly Thr Thr Leu Tyr Gln Leu Thr Thr Ala Gly Glu Ala
                 85                  90                  95

Val Ser Trp Asn Ser Ile Phe Ile Leu Met Ile Leu Ala Val Leu Ser
            100                 105                 110

Ile Leu Pro Ala Ile Phe Gln Lys Lys Leu Lys Gln Lys Phe Glu 
        115                 120                 125



<210> 1909
<211> 289
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1909
Met Met Asp Arg Ile Val Thr Gly Leu Ser Glu Ser Ser Xaa Lys Val
  1               5                  10                  15

Arg Leu Ala Ala Val Arg Cys Leu His Ser Leu Ser Arg Ser Val Gln
             20                  25                  30

Gln Leu Arg Thr Ser Phe Gln Asp His Ala Val Trp Lys Pro Leu Met
         35                  40                  45

Lys Val Leu Gln Asn Ala Pro Asp Glu Ile Leu Val Val Ala Ser Ser
     50                  55                  60

Met Leu Cys Asn Leu Leu Leu Glu Phe Ser Pro Ser Lys Glu Pro Ile
 65                  70                  75                  80

Leu Glu Ser Gly Ala Val Glu Leu Leu Cys Gly Leu Thr Gln Ser Glu
                 85                  90                  95

Asn Pro Ala Leu Arg Val Asn Gly Ile Trp Ala Leu Met Asn Met Ala
            100                 105                 110

Phe Gln Ala Glu Gln Lys Ile Lys Ala Asp Ile Leu Arg Ser Leu Ser
        115                 120                 125

Thr Glu Gln Leu Phe Arg Leu Leu Ser Asp Ser Asp Leu Asn Val Leu
    130                 135                 140

Met Lys Thr Leu Gly Leu Leu Arg Asn Leu Leu Ser Thr Arg Pro His
145                 150                 155                 160

Ile Asp Lys Ile Met Ser Thr His Gly Lys Gln Ile Met Gln Ala Val
                165                 170                 175

Thr Leu Ile Leu Glu Gly Glu His Asn Ile Glu Val Lys Glu Gln Thr
            180                 185                 190

Leu Cys Ile Leu Ala Asn Ile Ala Asp Gly Thr Thr Ala Lys Asp Leu
        195                 200                 205

Ile Met Thr Asn Asp Asp Ile Leu Gln Lys Ile Lys Tyr Tyr Met Gly
    210                 215                 220

His Ser His Val Lys Leu Gln Leu Ala Ala Met Phe Cys Ile Ser Asn
225                 230                 235                 240

Leu Ile Trp Asn Glu Glu Glu Gly Ser Gln Glu Arg Gln Asp Lys Leu
                245                 250                 255

Arg Asp Met Gly Ile Val Asp Ile Leu His Lys Leu Ser Gln Ser Pro
            260                 265                 270

Asp Ser Asn Leu Cys Asp Lys Ala Lys Met Ala Leu Gln Gln Tyr Leu
        275                 280                 285

Ala 




<210> 1910
<211> 159
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1910
Met Ala Asp Thr Val Leu Phe Glu Phe Leu His Thr Glu Met Val Ala
  1               5                  10                  15

Glu Leu Trp Ala His Asp Pro Asp Pro Gly Pro Gly Gly Gln Lys Met
             20                  25                  30

Ser Leu Ser Val Leu Glu Gly Met Gly Phe Arg Val Gly Gln Ala Leu
         35                  40                  45

Gly Glu Arg Leu Pro Arg Glu Thr Leu Ala Phe Arg Glu Glu Leu Asp
     50                  55                  60

Val Leu Lys Phe Leu Cys Lys Asp Leu Trp Val Ala Val Phe Gln Lys
 65                  70                  75                  80

Gln Met Asp Ser Leu Arg Thr Asn His Gln Gly Thr Tyr Val Leu Gln
                 85                  90                  95

Asp Asn Ser Phe Pro Leu Leu Leu Pro Met Xaa Ser Gly Leu Gln Tyr
            100                 105                 110

Leu Glu Glu Ala Pro Lys Phe Leu Ala Phe Thr Cys Gly Leu Leu Arg
        115                 120                 125

Gly Ala Leu Tyr Thr Leu Gly Ile Glu Ser Val Val Thr Ala Ser Val
    130                 135                 140

Ala Ala Leu Pro Val Cys Lys Phe Gln Val Val Ile Pro Lys Ser 
145                 150                 155



<210> 1911
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1911
Met Tyr Pro Gln Gly Thr Phe Val Ile Pro Leu Leu Val Thr Ala His
  1               5                  10                  15

Arg Asp Pro Thr Gln Phe Lys Asp Pro Asp Cys Phe Asn Pro Thr Asn
             20                  25                  30

Phe Leu Asp Lys Gly Lys Phe Gln Gly Asn Asp Ala Phe Met Pro Phe
         35                  40                  45

Ala Ser Gly Ala Gly Arg Gly Gly Arg Gly Pro Ala Trp Thr Gly Ser
     50                  55                  60

Gly Val Pro Gly Ala His Cys Ala Pro Val Tyr Pro Ala Lys Gln Met
 65                  70                  75                  80

Cys Leu Gly Thr Gly Leu Ala His Ser Gly Ile Phe Leu Phe Leu Thr
                 85                  90                  95

Ala Thr Leu Gln Arg Phe Cys Leu Leu Pro Val Val Arg Pro Gly Thr
            100                 105                 110

Ile Asn Leu Thr Cys Ser Ala Leu Ala Trp Ala Val Ser Pro Gln Thr
        115                 120                 125

Ser Ser Ser Ser Gln Trp Pro Ala Glu Val Arg Leu His Tyr Gly Gly
    130                 135                 140

Leu Thr Gly Pro Gln Thr Ser Ile Pro Ser Ser Val Asn Lys Gly Pro
145                 150                 155                 160

Lys Leu Gln Lys Lys Xaa Xaa Xaa 
                165



<210> 1912
<211> 178
<212> PRT
<213> Homo sapiens

<400> 1912
Met Thr Asn Pro Ala Ile Gln Asn Asp Phe Ser Tyr Tyr Arg Arg Thr
  1               5                  10                  15

Leu Ser Arg Met Arg Ile Asn Asn Val Pro Ala Glu Gly Glu Asn Glu
             20                  25                  30

Val Asn Asn Glu Leu Ala Asn Arg Met Ser Leu Phe Tyr Ala Glu Ala
         35                  40                  45

Thr Pro Met Leu Lys Thr Leu Ser Asp Ala Thr Thr Lys Phe Val Ser
     50                  55                  60

Glu Asn Lys Asn Leu Pro Ile Glu Asn Thr Thr Asp Cys Leu Ser Thr
 65                  70                  75                  80

Met Ala Ser Val Cys Arg Val Met Leu Glu Thr Pro Glu Tyr Arg Ser
                 85                  90                  95

Arg Phe Thr Asn Glu Glu Thr Val Ser Phe Cys Leu Arg Val Met Val
            100                 105                 110

Gly Val Ile Ile Leu Tyr Asp His Val His Pro Val Gly Ala Phe Ala
        115                 120                 125

Lys Thr Ser Lys Ile Asp Met Lys Gly Cys Ile Lys Val Leu Lys Asp
    130                 135                 140

Gln Pro Pro Asn Ser Val Glu Gly Leu Leu Asn Ala Leu Arg Tyr Thr
145                 150                 155                 160

Thr Lys His Leu Asn Asp Glu Thr Thr Ser Lys Gln Ile Lys Ser Met
                165                 170                 175

Leu Gln 




<210> 1913
<211> 120
<212> PRT
<213> Homo sapiens

<400> 1913
Met Ile Glu Ala Arg Lys Asn His Gly Leu Val Phe Val Lys Asp Lys
  1               5                  10                  15

Ile Phe Ala Val Gly Gly Gln Asn Gly Leu Gly Gly Leu Asp Asn Val
             20                  25                  30

Glu Tyr Tyr Asp Ile Lys Leu Asn Glu Trp Lys Met Val Ser Pro Met
         35                  40                  45

Pro Trp Lys Gly Val Thr Val Lys Cys Ala Ala Val Gly Ser Ile Val
     50                  55                  60

Tyr Val Leu Ala Gly Phe Gln Gly Val Gly Arg Leu Gly His Ile Leu
 65                  70                  75                  80

Glu Tyr Asn Thr Glu Thr Asp Lys Trp Val Ala Asn Ser Lys Val Arg
                 85                  90                  95

Ala Phe Pro Val Thr Ser Cys Leu Ile Cys Val Val Asp Thr Cys Gly
            100                 105                 110

Ala Asn Glu Glu Thr Leu Glu Thr 
        115                 120



<210> 1914
<211> 106
<212> PRT
<213> Homo sapiens

<400> 1914
Met Asp Val Phe Asp Met Glu Gln Gly Gly Trp Leu Lys Met Glu Arg
  1               5                  10                  15

Ser Phe Phe Leu Lys Lys Arg Arg Ala Asp Phe Val Ala Gly Ser Leu
             20                  25                  30

Ser Gly Arg Val Ile Val Ala Gly Gly Leu Gly Asn Gln Pro Thr Val
         35                  40                  45

Leu Glu Thr Ala Glu Ala Phe His Pro Gly Lys Asn Lys Trp Glu Ile
     50                  55                  60

Leu Pro Ala Met Pro Thr Pro Arg Cys Ala Cys Ser Ser Ile Val Val
 65                  70                  75                  80

Lys Asn Cys Leu Leu Ala Val Gly Gly Val Asn Gln Gly Leu Ser Asp
                 85                  90                  95

Ala Val Glu Ala Leu Cys Val Ser Asp Ser 
            100                 105



<210> 1915
<211> 111
<212> PRT
<213> Homo sapiens

<400> 1915
Met Met Leu Thr Arg Arg Phe Ile Ile Leu Asp Pro Ser Gln Thr His
  1               5                  10                  15

Phe Ser Leu Ala Glu Val Thr Phe Leu Arg Leu Asn Asn Trp Ile Gln
             20                  25                  30

Gly His Asn Arg Phe Val Glu Arg Lys Cys Gly Ser Ala Phe Thr Arg
         35                  40                  45

Asp Ser Gly Gln Glu Ala Leu Ser Ile Pro Asp Gly Phe Ile His Pro
     50                  55                  60

Leu Leu Lys Cys Ser Ala Leu Gly Trp Val Leu Leu Pro Pro Ala Cys
 65                  70                  75                  80

Ser Leu Val Gly Phe Cys Arg Arg Ala Ala Tyr Val Phe Val Asn Gln
                 85                  90                  95

Leu Glu Ser Gln Phe Leu Trp Val Glu Phe Arg Pro Phe Trp Pro 
            100                 105                 110



<210> 1916
<211> 169
<212> PRT
<213> Homo sapiens

<400> 1916
Met Glu Ser Lys Leu Thr Ile Gln Glu Thr Gln Leu Gly Asp Ser Ala
  1               5                  10                  15

Asn Leu Thr Cys Arg Ala Phe Phe Gly Tyr Ser Gly Asp Val Ser Pro
             20                  25                  30

Leu Ile Tyr Trp Met Lys Gly Glu Lys Phe Ile Glu Asp Leu Asp Glu
         35                  40                  45

Asn Arg Val Trp Glu Ser Asp Ile Arg Ile Leu Lys Glu His Leu Gly
     50                  55                  60

Glu Gln Glu Val Ser Ile Ser Leu Ile Val Asp Ser Val Glu Glu Gly
 65                  70                  75                  80

Asp Leu Gly Asn Tyr Ser Cys Tyr Val Glu Asn Gly Asn Gly Arg Arg
                 85                  90                  95

His Ala Ser Val Leu Leu His Lys Arg Glu Leu Met Tyr Thr Val Glu
            100                 105                 110

Leu Ala Gly Gly Leu Gly Ala Ile Leu Leu Leu Leu Val Cys Leu Val
        115                 120                 125

Thr Ile Tyr Lys Cys Tyr Lys Ile Glu Ile Met Leu Phe Tyr Arg Asn
    130                 135                 140

His Phe Gly Ala Glu Glu Leu Asp Gly Asp Asn Lys Asp Tyr Asp Ala
145                 150                 155                 160

Tyr Leu Ser Tyr Thr Lys Ser Gly Ser 
                165



<210> 1917
<211> 319
<212> PRT
<213> Homo sapiens

<400> 1917
Met Gln Leu Tyr Leu Leu Leu Gln Lys Lys His Gly Glu Lys Phe Val
  1               5                  10                  15

Asn Ser Trp Leu Met Gln Leu His Asn Gln Leu Thr Asp Met Glu Lys
             20                  25                  30

Cys Ile Leu Lys Tyr Met Lys Gly Thr Ser Ile Val Val Pro Glu Pro
         35                  40                  45

Leu His Phe Leu Leu Pro Gly Lys Lys Asn Leu Val Thr Ile Ser Tyr
     50                  55                  60

Pro Ser Gly Ile Pro Asp Gly Gln Leu Gln Ala Tyr Arg Lys Glu Leu
 65                  70                  75                  80

His Asp Leu Phe Asn Leu Pro His Asp Arg Pro Tyr Phe Lys Arg Ser
                 85                  90                  95

Asn Ala Tyr His Phe Pro Asp Glu Pro Tyr Lys Asp Gly Tyr Ile Arg
            100                 105                 110

Asn Pro His Thr Tyr Leu Asn Pro Pro Asn Met Glu Thr Gly Met Ile
        115                 120                 125

Tyr Val Val Gln Gly Ile Tyr Gly Tyr His His Tyr Met Gln Asp Arg
    130                 135                 140

Ile Asp Asp Asn Gly Trp Gly Cys Ala Tyr Arg Ser Leu Gln Thr Ile
145                 150                 155                 160

Cys Ser Trp Phe Lys His Gln Gly Tyr Thr Glu Arg Ser Ile Pro Thr
                165                 170                 175

His Arg Glu Ile Gln Gln Ala Leu Val Asp Ala Gly Asp Lys Pro Ala
            180                 185                 190

Thr Phe Val Gly Ser Arg Gln Trp Ile Gly Ser Ile Glu Val Gln Leu
        195                 200                 205

Val Leu Asn Gln Leu Ile Gly Ile Thr Ser Lys Ile Leu Phe Val Ser
    210                 215                 220

Gln Gly Ser Glu Ile Ala Ser Gln Gly Arg Glu Leu Ala Asn His Phe
225                 230                 235                 240

Gln Ser Glu Gly Thr Pro Val Met Ile Gly Gly Gly Val Leu Ala His
                245                 250                 255

Thr Ile Leu Gly Val Ala Trp Asn Glu Ile Thr Gly Gln Ile Lys Phe
            260                 265                 270

Leu Ile Leu Asp Pro His Tyr Thr Gly Ala Glu Asp Leu Gln Val Ile
        275                 280                 285

Leu Glu Lys Gly Trp Cys Gly Trp Lys Gly Pro Asp Phe Trp Asn Lys
    290                 295                 300

Asp Ala Tyr Tyr Asn Leu Cys Leu Pro Gln Arg Pro Asn Met Ile 
305                 310                 315



<210> 1918
<211> 327
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (307)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1918
Met Ser Tyr Leu Glu Ser Lys Gly Leu Leu Ala Thr Ala Ser Glu Asp
  1               5                  10                  15

Arg Ser Val Arg Ile Trp Lys Val Gly Asp Leu Arg Val Pro Gly Gly
             20                  25                  30

Arg Val Gln Asn Ile Gly His Cys Phe Gly His Ser Ala Arg Val Trp
         35                  40                  45

Gln Val Lys Leu Leu Glu Asn Tyr Leu Ile Ser Ala Gly Glu Asp Cys
     50                  55                  60

Val Cys Leu Val Trp Ser His Glu Gly Glu Ile Leu Gln Ala Phe Arg
 65                  70                  75                  80

Gly His Gln Gly Arg Gly Ile Arg Ala Ile Ala Ala His Glu Arg Gln
                 85                  90                  95

Ala Trp Val Ile Thr Gly Gly Asp Asp Ser Arg His Arg Leu Xaa His
            100                 105                 110

Leu Val Gly Arg Gly Tyr Arg Gly Leu Gly Val Ser Ala Leu Cys Phe
        115                 120                 125

Lys Ser Arg Ser Arg Pro Gly Thr Leu Lys Ala Val Thr Leu Ala Gly
    130                 135                 140

Ser Trp Arg Leu Leu Ala Val Thr Asp Thr Gly Ala Leu Tyr Leu Tyr
145                 150                 155                 160

Asp Val Glu Val Lys Cys Trp Glu Gln Leu Leu Glu Asp Lys His Phe
                165                 170                 175

Gln Ser Tyr Cys Leu Leu Glu Ala Ala Pro Gly Pro Glu Gly Phe Gly
            180                 185                 190

Leu Cys Ala Met Ala Asn Gly Glu Gly Arg Val Lys Val Val Pro Ile
        195                 200                 205

Asn Thr Pro Thr Ala Ala Val Asp Gln Thr Leu Phe Pro Gly Lys Val
    210                 215                 220

His Ser Leu Ser Trp Ala Leu Arg Gly Tyr Glu Glu Leu Leu Leu Leu
225                 230                 235                 240

Ala Ser Gly Pro Gly Gly Val Val Ala Cys Leu Glu Ile Ser Ala Ala
                245                 250                 255

Pro Ser Gly Lys Ala Ile Phe Val Lys Glu Arg Cys Arg Tyr Leu Leu
            260                 265                 270

Pro Pro Ser Lys Gln Arg Trp His Thr Cys Ser Ala Phe Leu Pro Pro
        275                 280                 285

Gly Asp Phe Leu Val Cys Gly Asp Arg Arg Gly Ser Val Leu Leu Phe
    290                 295                 300

Pro Ser Xaa Pro Gly Leu Leu Lys Asp Pro Gly Val Gly Gly Lys Ala
305                 310                 315                 320

Arg Ala Gly Ala Gly Ala Leu 
                325



<210> 1919
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1919
Met Ser Gln Gly Arg Gly Lys Tyr Asp Phe Tyr Ile Gly Leu Gly Leu
  1               5                  10                  15

Ala Met Ser Ser Ser Ile Phe Ile Gly Gly Ser Phe Ile Leu Lys Lys
             20                  25                  30

Lys Gly Leu Leu Arg Leu Ala Arg Lys Gly Ser Met Arg Ala Gly Gln
         35                  40                  45

Gly Gly His Ala Tyr Leu Lys Glu Trp Leu Trp Trp Ala Gly Leu Leu
     50                  55                  60

Ser Met Gly Ala Gly Glu Val Ala Asn Phe Ala Ala Tyr Ala Phe Ala
 65                  70                  75                  80

Pro Ala Thr Leu Val Thr Pro Leu Gly Ala Leu Ser Val Leu Val Ser
                 85                  90                  95

Ala Ile Leu Ser Ser Tyr Phe Leu Asn Glu Arg Leu Asn Leu His Gly
            100                 105                 110

Lys Ile Gly Cys Cys Xaa Val Phe Xaa Asp Leu Gln Leu 
        115                 120                 125



<210> 1920
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1920
Met Val Thr Gly Leu Met Thr Lys Ala Glu Lys Ser Pro Lys Gly Phe
  1               5                  10                  15

Leu Glu Ser Tyr Glu Glu Met Leu Ser Tyr Ala Leu Arg Pro Glu Thr
             20                  25                  30

Trp Ala Thr Thr Arg Leu Glu Leu Glu Gly Arg Gly Val Val Cys Met
         35                  40                  45

Ser Phe Phe Asp Ile Val Leu Asp Phe Ile Leu Met Asp Ala Phe Glu
     50                  55                  60

Asp Leu Glu Asn Pro Pro Ala Ser Val Leu Ala Val Leu Arg Asn Arg
 65                  70                  75                  80

Trp Leu Ser Asp Ser Phe Lys Glu Thr Ala Leu Ala Thr Ala Cys Trp
                 85                  90                  95

Ser Val Leu Lys Ala Lys Arg Arg Leu Leu Met Val Pro Asp Gly Phe
            100                 105                 110

Ile Ser His Phe Tyr Ser Val Ser Glu His Val Ser Pro Val Leu Xaa
        115                 120                 125

Xaa Gly Phe Leu Gly Pro Lys Pro 
    130                 135



<210> 1921
<211> 318
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (308)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1921
Met Ala Val Asp Met Arg Arg Ala Leu Phe Ser Ser Leu Leu Arg Gln
  1               5                  10                  15

Asp Ile Thr Phe Phe Asp Ala Asn Lys Thr Gly Gln Leu Val Ser Arg
             20                  25                  30

Leu Thr Thr Asp Val Gln Glu Phe Lys Ser Ser Phe Lys Leu Val Ile
         35                  40                  45

Ser Gln Gly Leu Arg Xaa Cys Thr Gln Val Ala Gly Cys Leu Val Ser
     50                  55                  60

Leu Ser Met Leu Ser Thr Arg Leu Thr Xaa Leu Leu Met Val Ala Thr
 65                  70                  75                  80

Pro Ala Leu Met Gly Val Gly Thr Leu Met Gly Ser Gly Leu Arg Lys
                 85                  90                  95

Leu Ser Arg Gln Cys Gln Glu Gln Ile Ala Arg Ala Met Gly Val Xaa
            100                 105                 110

Xaa Glu Ala Leu Gly Asn Val Arg Thr Val Arg Ala Phe Ala Met Glu
        115                 120                 125

Gln Arg Glu Glu Glu Arg Tyr Gly Ala Glu Leu Glu Ala Cys Arg Cys
    130                 135                 140

Arg Ala Glu Glu Leu Gly Arg Gly Ile Ala Leu Phe Gln Gly Leu Ser
145                 150                 155                 160

Asn Ile Ala Phe Asn Cys Met Val Phe Gly Tyr Pro Ile Tyr Trp Gly
                165                 170                 175

Leu Pro Cys Gly Arg Thr Ala Ala Asp Arg Gly Asp Leu Met Ser Phe
            180                 185                 190

Leu Val Ala Ser Gln Thr Val Gln Arg Ser Met Ala Asn Leu Ser Val
        195                 200                 205

Leu Phe Gly Gln Val Val Arg Gly Leu Ser Ala Gly Ala Arg Val Phe
    210                 215                 220

Glu Tyr Met Ala Leu Asn Pro Cys Ile Pro Leu Ser Gly Gly Cys Cys
225                 230                 235                 240

Val Pro Lys Glu Gln Leu Arg Gly Ser Val Thr Phe Gln Asn Val Cys
                245                 250                 255

Phe Ser Tyr Pro Cys Arg Pro Gly Phe Glu Val Leu Lys Asp Phe Thr
            260                 265                 270

Leu Thr Leu Pro Pro Gly Lys Ile Val Ala Leu Val Gly His Leu Ala
        275                 280                 285

Glu Glu Arg Pro Pro Trp Leu Pro Cys Trp Ser Ala Ser Thr Thr His
    290                 295                 300

Gly Arg Arg Xaa Asp Ala Gly Trp Ala Gly Pro Ala His Pro 
305                 310                 315



<210> 1922
<211> 112
<212> PRT
<213> Homo sapiens

<400> 1922
Met Gly Asn Arg Thr Gln Asp Pro Lys Leu Gln Gly Asp Cys Pro Pro
  1               5                  10                  15

Met Asn Thr Gln Ser Gly His His Leu Pro Ser Thr Leu Cys Pro Arg
             20                  25                  30

Thr Ala Val Pro Ile His Glu His Arg Val Asn Ile Cys Arg Val Arg
         35                  40                  45

Thr Ser Gly Ser Leu Gly His Gly Thr Ala Ala Gly Leu Thr Thr Asp
     50                  55                  60

Ser Thr Trp Pro Ser Ser Arg Pro Pro Trp Arg Pro Gly Ala Ser Ser
 65                  70                  75                  80

Pro Pro Leu Pro Leu Thr Leu Ser Pro Pro Arg Ser Cys Leu Ser Gly
                 85                  90                  95

Ile Ile Trp Gly Phe Phe Phe Trp Gly Ile Ile Leu Leu His Asp Pro
            100                 105                 110






<210> 1923
<211> 244
<212> PRT
<213> Homo sapiens

<400> 1923
Met Gln Pro Pro Gly Pro Pro Pro Ala Tyr Ala Pro Thr Asn Gly Asp
  1               5                  10                  15

Phe Thr Phe Val Ser Ser Ala Asp Ala Glu Asp Leu Ser Gly Ser Ile
             20                  25                  30

Ala Ser Pro Asp Val Lys Leu Asn Leu Gly Gly Asp Phe Ile Lys Glu
         35                  40                  45

Ser Thr Ala Thr Thr Phe Leu Arg Gln Arg Gly Tyr Gly Trp Leu Leu
     50                  55                  60

Glu Val Glu Asp Asp Asp Pro Glu Asp Asn Lys Pro Leu Leu Glu Glu
 65                  70                  75                  80

Leu Asp Ile Asp Leu Lys Asp Ile Tyr Tyr Lys Ile Arg Cys Val Leu
                 85                  90                  95

Met Pro Met Pro Ser Leu Gly Phe Asn Arg Gln Val Val Arg Asp Asn
            100                 105                 110

Pro Asp Phe Trp Gly Pro Leu Ala Val Val Leu Phe Phe Ser Met Ile
        115                 120                 125

Ser Leu Tyr Gly Gln Phe Arg Val Val Ser Trp Ile Ile Thr Ile Trp
    130                 135                 140

Ile Phe Gly Ser Leu Thr Ile Phe Leu Leu Ala Arg Val Leu Gly Gly
145                 150                 155                 160

Glu Val Ala Tyr Gly Gln Val Leu Gly Val Ile Gly Tyr Ser Leu Leu
                165                 170                 175

Pro Leu Ile Val Ile Ala Pro Val Leu Leu Val Val Gly Ser Phe Glu
            180                 185                 190

Val Val Ser Thr Leu Ile Lys Leu Phe Gly Val Phe Trp Ala Ala Tyr
        195                 200                 205

Ser Ala Ala Ser Leu Leu Val Gly Glu Glu Phe Lys Thr Lys Lys Pro
    210                 215                 220

Leu Leu Ile Tyr Pro Ile Phe Leu Leu Tyr Ile Tyr Phe Leu Ser Leu
225                 230                 235                 240

Tyr Thr Gly Val 




<210> 1924
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (65)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1924
Met Gln Ile Leu Glu Ser Ser Xaa Pro Ile Val Lys Cys Glu His Phe
  1               5                  10                  15

Leu Ile Leu His Phe Gln Val Asp Ile Ser Thr Gln Lys Gln Ala Leu
             20                  25                  30

Gly Lys Ile Ser Lys Phe Ile Ala Tyr Val Cys Val Cys Val Arg Val
         35                  40                  45

Glu Thr Glu Val Cys Val Cys Val His Val Trp Arg Val Leu Pro His
     50                  55                  60

Xaa Val Gln Phe Ser Val Phe Val Cys Leu Lys Ala Cys Glu Asp Leu
 65                  70                  75                  80

Thr Val Gly Phe Pro Leu Tyr Ser Val Tyr Ala Phe Phe Leu Ala His
                 85                  90                  95

Trp Ser Asn Gly Cys Tyr Tyr 
            100



<210> 1925
<211> 247
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (44)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (196)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (247)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1925
Met Asn Ser Asn Ile Trp Gln Ile Cys Ile Gln Leu Glu Gly Ile Gly
  1               5                  10                  15

Gln Phe Ala Tyr Ala Leu Gly Lys Asp Phe Cys Leu Leu Leu Met Ser
             20                  25                  30

Ala Leu Tyr Pro Val Leu Glu Lys Ala Gly Asp Xaa Thr Leu Leu Ile
         35                  40                  45

Ser Gln Val Xaa Thr Ser Thr Met Met Asp Val Cys Arg Ala Cys Gly
     50                  55                  60

Tyr Asp Ser Leu Gln His Leu Ile Asn Gln Asn Ser Asp Tyr Leu Val
 65                  70                  75                  80

Asn Gly Ile Ser Leu Asn Leu Arg His Leu Ala Leu His Pro His Thr
                 85                  90                  95

Pro Lys Val Leu Glu Val Met Leu Arg Asn Ser Asp Ala Asn Leu Leu
            100                 105                 110

Pro Leu Val Ala Asp Val Val Gln Asp Val Leu Ala Thr Leu Asp Gln
        115                 120                 125

Phe Tyr Xaa Lys Arg Ala Ala Ser Phe Val Ser Val Leu His Ala Leu
    130                 135                 140

Met Ala Ala Leu Ala Gln Trp Phe Pro Asp Thr Gly Asn Leu Gly His
145                 150                 155                 160

Leu Gln Glu Gln Ser Leu Gly Glu Glu Gly Ser His Leu Asn Gln Arg
                165                 170                 175

Pro Ala Ala Leu Glu Lys Ser Thr Thr Thr Ala Gly Arg His Arg Thr
            180                 185                 190

Val Phe Ala Xaa Thr Thr Ser Lys Arg Arg Met Trp Ala Asp Gly Lys
        195                 200                 205

Cys Xaa Arg Ile Leu Ile Asn Glu Glu Glu Glu Gln Phe Ser Pro Ser
    210                 215                 220

Gln Ser Gly Met Arg Met Asp Thr Arg Ser Arg Leu Trp Arg Pro Pro
225                 230                 235                 240

Met Ala Ile Ala Asp Ser Xaa 
                245



<210> 1926
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (59)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1926
Met Leu Leu Leu Pro Thr Pro Asn Leu Trp Ala Gly Gln Ala His Ser
  1               5                  10                  15

Ser Pro Thr Val Ile Ala Arg Thr Ala Phe Asp Leu Thr Gln Arg Lys
             20                  25                  30

His Leu Pro Pro Val Gly Arg Glu Pro Gly Arg Gly Phe Pro Trp Gln
         35                  40                  45

Xaa Tyr Cys Ser Leu Val Ile Glu Phe Phe Xaa Phe Cys Tyr Met Val
     50                  55                  60

Leu Trp Gln Arg Thr Gly Cys Arg Cys Ser Leu Gly Tyr Phe Trp Lys
 65                  70                  75                  80

His Phe Ser Phe Ser Xaa Ile Leu Pro Xaa Leu Ala His Gln Ser Pro
                 85                  90                  95

Ser Ser Gln Lys Gly Asp Xaa Gly Ser Ser Ala Gln Thr Ile Lys His
            100                 105                 110

Phe Trp Arg Cys His Lys Leu Pro 
        115                 120



<210> 1927
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1927
Met Trp Gln Ser Trp Gly Ser Ser Ser Cys Ser His Cys Xaa Thr Ala
  1               5                  10                  15

Ala Thr Ser Gly Thr Gln Phe Arg Thr Pro Arg Glu Ala Gln Ala Pro
             20                  25                  30

Gly Val Ala Gly Asp Pro Arg Gly Lys Trp Gln Gly Arg Thr Leu Glu
         35                  40                  45

Gln Ser Gln Trp Asn Val Thr Ile Ala Gln Val Gly Ile Phe Val Cys
     50                  55                  60

Phe Val His Cys Cys Thr Pro Ser Pro Gln His Ser Ala Cys Pro Gly
 65                  70                  75                  80

Gln Val Pro Ser Lys His Leu Gly Ser Asn Ala Ser Val Leu Pro Ala
                 85                  90                  95

Ala Pro Ala Asn Arg Pro Pro Thr Gln Ala Leu Pro Ser Xaa Ser Thr
            100                 105                 110

Ala Thr Thr Ala Ala His Leu Cys Trp His Arg Ser Leu Phe Pro Gly
        115                 120                 125

Leu Pro Glu Ile Pro Ser Pro His Ser Ala Arg Gly Lys Leu Leu Lys
    130                 135                 140

Leu Arg Ala Ser Pro His Ser Val His Ser Lys Val Leu Ser Lys Gly
145                 150                 155                 160

Xaa Leu Leu Leu Gly Xaa Ile Asn Pro Arg Ile Leu Ser Leu Ala Leu
                165                 170                 175






<210> 1928
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1928
Met Phe Gly Ala Gly Asp Glu Asp Asp Thr Asp Phe Leu Ser Pro Ser
  1               5                  10                  15

Gly Gly Ala Arg Leu Ala Ser Leu Phe Gly Leu Asp Xaa Ala Ala Ala
             20                  25                  30

Gly His Gly Asn Glu Phe Phe Gln Tyr Thr Ala Pro Lys Gln Pro Lys
         35                  40                  45

Lys Gly Gln Gly Thr Ala Ala Thr Gly Asn Gln Ala Thr Pro Lys Thr
     50                  55                  60

Ala Pro Ala Thr Met Ser Xaa Pro Thr Ile Leu Val Ala Thr Ala Val
 65                  70                  75                  80

His Ala Tyr Arg Tyr Thr Asn Gly Gln Tyr Val Lys Gln Gly Lys Phe
                 85                  90                  95

Gly Ala Ala Val Leu Gly Asn His Thr Ala Arg Glu Xaa Xaa Val Leu
            100                 105                 110

Pro His Leu Met Tyr Ile Gln Met Ser Gln Ile Ile Pro Met Ser Trp
        115                 120                 125

Leu Leu Ser Gly Leu Pro Asp Val Leu Phe Ile Arg Arg 
    130                 135                 140



<210> 1929
<211> 237
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (232)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1929
Met Ala Val Val Ser Glu Asp Asp Phe Gln His Ser Ser Asn Ser Thr
  1               5                  10                  15

Tyr Xaa Thr Thr Ser Ser Ser Leu Arg Ala Asp Gln Glu Ala Leu Leu
             20                  25                  30

Xaa Xaa Xaa Leu Asp Arg Pro Pro Pro Gly Leu Gln Arg Pro Glu Asp
         35                  40                  45

Arg Phe Cys Gly Thr Tyr Ile Ile Phe Phe Ser Leu Gly Ile Gly Ser
     50                  55                  60

Leu Leu Pro Trp Asn Phe Phe Ile Thr Ala Lys Glu Tyr Trp Met Phe
 65                  70                  75                  80

Lys Leu Arg Asn Ser Ser Ser Pro Ala Thr Gly Glu Asp Pro Glu Gly
                 85                  90                  95

Ser Asp Ile Leu Asn Tyr Phe Glu Ser Tyr Leu Ala Val Ala Ser Thr
            100                 105                 110

Val Pro Ser Met Leu Cys Leu Val Ala Asn Phe Leu Leu Val Asn Arg
        115                 120                 125

Val Ala Val His Ile Arg Val Leu Ala Ser Leu Thr Val Ile Leu Ala
    130                 135                 140

Ile Phe Met Val Ile Thr Ala Leu Val Lys Val Asp Thr Phe Ser Trp
145                 150                 155                 160

Thr Arg Gly Phe Phe Ala Val Thr Ile Val Cys Met Val Ile Leu Ser
                165                 170                 175

Gly Ala Ser Thr Val Phe Ser Ser Ser Ile Tyr Gly Met Thr Gly Ser
            180                 185                 190

Phe Pro Met Arg Asn Ser Gln Ala Leu Ile Ser Gly Gly Ala Met Gly
        195                 200                 205

Gly Thr Val Ser Ala Val Ala Ser Leu Val Asp Leu Ala Ala Ser Ser
    210                 215                 220

Asp Val Arg Asn Ser Ala Leu Xaa Leu Leu Xaa Asp Gly 
225                 230                 235



<210> 1930
<211> 101
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1930
Met Arg Gly Arg Arg Asp Gly Pro Gln Asp Ser Cys Asn Thr Thr Trp
  1               5                  10                  15

Glu His Met Trp Xaa Leu Asp Val Ala Ser Ala Xaa Phe Ser Thr Thr
             20                  25                  30

Tyr Leu Pro Ser Thr Thr Val Leu Asp Val Gly Ile Leu Ser Pro Ser
         35                  40                  45

Leu Glu Gly Gly Trp Arg Trp Arg Ala Thr Arg Asp Thr Phe Pro Val
     50                  55                  60

Leu His Cys Ser Met Leu Gln Ser Phe Cys Glu Trp Pro Gly Pro Xaa
 65                  70                  75                  80

Pro Ser Gln Phe His Tyr Leu Val Phe Tyr Ile Val Ile Arg Ile Ile
                 85                  90                  95

Leu Asn Ile Ala Phe 
            100



<210> 1931
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1931
Met Ser Arg His Ala Gly Pro Val Trp Lys Ser Tyr Leu Lys Ser Ser
  1               5                  10                  15

Lys Cys Trp Lys Lys Gly Leu Gly Gly Gly Gly Gly Ser Cys Arg Ser
             20                  25                  30

Pro Gln Ala Pro Val Ser Gly Met Asn Val Ala Ser His Trp Asp Ser
         35                  40                  45

Ser Leu Ala Arg Lys Xaa Xaa Phe Glu Asp Tyr Gln Tyr Trp Gly Val
     50                  55                  60

Gly Val Lys Pro Asp Leu Thr Gln Gly Glu Ile Ser Gly Pro Arg His
 65                  70                  75                  80

Pro Glu His Pro Pro His Pro Asn Ile Leu Leu Ala Leu Ser Leu Pro
                 85                  90                  95

Leu Leu Pro Thr Pro Phe Val Leu Gly Leu Arg Ala Pro Arg Val Leu
            100                 105                 110

Arg 




<210> 1932
<211> 172
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1932
Met His Thr His Val Asp Ser Tyr Ala Lys Ile His Leu Trp Ser Phe
  1               5                  10                  15

Phe Cys Ile Ser Arg Met Val Phe Glu Leu Asn Val His Leu Val Leu
             20                  25                  30

Gly Thr Ile Val Phe Ile Leu Lys Leu Val Phe Leu Thr Val Ala Cys
         35                  40                  45

Ser Leu Lys Arg Tyr Gln Cys Thr Phe Phe Gly Ser Gly Lys Lys Lys
     50                  55                  60

Asp Arg Leu Pro Gln Tyr Ile Phe Leu Ile Trp Gln Asp Asn Ile Val
 65                  70                  75                  80

Gln Ile Ile Cys Met Leu Gln Lys Lys Lys Lys Arg Glu Lys Gln Lys
                 85                  90                  95

Ser Val Thr Leu Gln Met Arg Ser His Ile Met Ala Val Trp Gly Ser
            100                 105                 110

Leu Leu Glu Cys His Met Asp Gly Cys His Arg Gly Cys Thr Tyr Pro
        115                 120                 125

Phe Leu Xaa Leu Phe Pro Ala Ala Ile Leu Tyr Ala Val Leu Gln Ala
    130                 135                 140

Asn Asn Val Gly Leu Xaa Cys Ser Val Leu Phe Val Pro Phe Leu Leu
145                 150                 155                 160

Ser Pro Tyr Ile Pro Ala Ser Tyr Leu His Met Gln 
                165                 170



<210> 1933
<211> 643
<212> PRT
<213> Homo sapiens

<400> 1933
Met Cys Gly Ile Cys Cys Ser Val Asn Phe Ser Ala Glu His Phe Ser
  1               5                  10                  15

Gln Asp Leu Lys Glu Asp Leu Leu Tyr Asn Leu Lys Gln Arg Gly Pro
             20                  25                  30

Asn Ser Ser Lys Gln Leu Leu Lys Ser Asp Val Asn Tyr Gln Cys Leu
         35                  40                  45

Phe Ser Ala His Val Leu His Leu Arg Gly Val Leu Thr Thr Gln Pro
     50                  55                  60

Val Glu Asp Glu Arg Gly Asn Val Phe Leu Trp Asn Gly Glu Ile Phe
 65                  70                  75                  80

Ser Gly Ile Lys Val Glu Ala Glu Glu Asn Asp Thr Gln Ile Leu Phe
                 85                  90                  95

Asn Tyr Leu Ser Ser Cys Lys Asn Glu Ser Glu Ile Leu Ser Leu Phe
            100                 105                 110

Ser Glu Val Gln Gly Pro Trp Ser Phe Ile Tyr Tyr Gln Ala Ser Ser
        115                 120                 125

His Tyr Leu Trp Phe Gly Arg Asp Phe Phe Gly Arg Arg Ser Leu Leu
    130                 135                 140

Trp His Phe Ser Asn Leu Gly Lys Ser Phe Cys Leu Ser Ser Val Gly
145                 150                 155                 160

Thr Gln Thr Ser Gly Leu Ala Asn Gln Trp Gln Glu Val Pro Ala Ser
                165                 170                 175

Gly Leu Phe Arg Ile Asp Leu Lys Ser Thr Val Ile Ser Arg Cys Ile
            180                 185                 190

Ile Leu Gln Leu Tyr Pro Trp Lys Tyr Ile Ser Arg Glu Asn Ile Ile
        195                 200                 205

Glu Glu Asn Val Asn Ser Leu Ser Gln Ile Ser Ala Asp Leu Pro Ala
    210                 215                 220

Phe Val Ser Val Val Ala Asn Glu Ala Lys Leu Tyr Leu Glu Lys Pro
225                 230                 235                 240

Val Val Pro Leu Asn Met Met Leu Pro Gln Ala Ala Leu Glu Thr His
                245                 250                 255

Cys Ser Asn Ile Ser Asn Val Pro Pro Thr Arg Glu Ile Leu Gln Val
            260                 265                 270

Phe Leu Thr Asp Val His Met Lys Glu Val Ile Gln Gln Phe Ile Asp
        275                 280                 285

Val Leu Ser Val Ala Val Lys Lys Arg Val Leu Cys Leu Pro Arg Asp
    290                 295                 300

Glu Asn Leu Thr Ala Asn Glu Val Leu Lys Thr Cys Asp Arg Lys Ala
305                 310                 315                 320

Asn Val Ala Ile Leu Phe Ser Gly Gly Ile Asp Ser Met Val Ile Ala
                325                 330                 335

Thr Leu Ala Asp Arg His Ile Pro Leu Asp Glu Pro Ile Asp Leu Leu
            340                 345                 350

Asn Val Ala Phe Ile Ala Glu Glu Lys Thr Met Pro Thr Thr Phe Asn
        355                 360                 365

Arg Glu Gly Asn Lys Gln Lys Asn Lys Cys Glu Ile Pro Ser Glu Glu
    370                 375                 380

Phe Ser Lys Asp Val Ala Ala Ala Ala Ala Asp Ser Pro Asn Lys His
385                 390                 395                 400

Val Ser Val Pro Asp Arg Ile Thr Gly Arg Ala Gly Leu Lys Glu Leu
                405                 410                 415

Gln Ala Val Ser Pro Ser Arg Ile Trp Asn Phe Val Glu Ile Asn Val
            420                 425                 430

Ser Met Glu Glu Leu Gln Lys Leu Arg Arg Thr Arg Ile Cys His Leu
        435                 440                 445

Ile Arg Pro Leu Asp Thr Val Leu Asp Asp Ser Ile Gly Cys Ala Val
    450                 455                 460

Trp Phe Ala Ser Arg Gly Ile Gly Trp Leu Val Ala Gln Glu Gly Val
465                 470                 475                 480

Lys Ser Tyr Gln Ser Asn Ala Lys Val Val Leu Thr Gly Ile Gly Ala
                485                 490                 495

Asp Glu Gln Leu Ala Gly Tyr Ser Arg His Arg Val Arg Phe Gln Ser
            500                 505                 510

His Gly Leu Glu Gly Leu Asn Lys Glu Ile Met Met Glu Leu Gly Arg
        515                 520                 525

Ile Ser Ser Arg Asn Leu Gly Arg Asp Asp Arg Val Ile Gly Asp His
    530                 535                 540

Gly Lys Glu Ala Arg Phe Pro Phe Leu Asp Glu Asn Val Val Ser Phe
545                 550                 555                 560

Leu Asn Ser Leu Pro Ile Trp Glu Lys Ala Asn Leu Thr Leu Pro Arg
                565                 570                 575

Gly Ile Gly Glu Lys Leu Leu Leu Arg Leu Ala Ala Val Glu Leu Gly
            580                 585                 590

Leu Thr Ala Ser Ala Leu Leu Pro Lys Arg Ala Met Gln Phe Gly Ser
        595                 600                 605

Arg Ile Ala Lys Met Glu Lys Ile Asn Glu Lys Ala Ser Asp Lys Cys
    610                 615                 620

Gly Arg Leu Gln Ile Met Ser Leu Glu Asn Leu Ser Ile Glu Lys Glu
625                 630                 635                 640

Thr Lys Leu 




<210> 1934
<211> 121
<212> PRT
<213> Homo sapiens

<400> 1934
Met Ala Phe Ser Ala Glu Gln Asp Leu Gln Leu Cys Val Gly Gly Cys
  1               5                  10                  15

Pro Pro Ser Gln Arg Leu Ser Arg Ser Glu Arg Asn Arg Arg Gly Ala
             20                  25                  30

Ile Thr Ile Asp Thr Ala Arg Arg Leu Cys Lys Glu Gly Leu Pro Val
         35                  40                  45

Glu Asp Ala Tyr Phe His Ser Cys Val Phe Asp Val Leu Ile Ser Gly
     50                  55                  60

Asp Pro Asn Phe Thr Val Ala Ala Gln Ala Ala Leu Glu Asp Ala Arg
 65                  70                  75                  80

Ala Phe Leu Pro Asp Leu Glu Lys Leu His Leu Phe Pro Ser Asp Ala
                 85                  90                  95

Gly Val Pro Leu Ser Ser Ala Thr Leu Leu Ala Pro Leu Leu Ser Gly
            100                 105                 110

Leu Phe Val Leu Trp Leu Cys Ile Gln 
        115                 120



<210> 1935
<211> 290
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1935
Met Gly Ala Tyr His Thr Ile Glu Leu Glu Pro Asn Arg Gln Phe Thr
  1               5                  10                  15

Leu Ala Lys Lys Gln Trp Asp Ser Val Val Leu Glu Arg Ile Glu Gln
             20                  25                  30

Ala Cys Xaa Pro Ala Trp Ser Ala Asp Val Ala Ala Val Val Met Gln
         35                  40                  45

Glu Gly Leu Ala His Ile Cys Leu Val Thr Pro Ser Met Thr Leu Thr
     50                  55                  60

Arg Ala Lys Val Glu Val Asn Ile Pro Arg Lys Arg Lys Gly Asn Cys
 65                  70                  75                  80

Ser Gln His Asp Arg Ala Leu Glu Arg Phe Tyr Glu Gln Val Val Gln
                 85                  90                  95

Ala Ile Gln Arg His Ile His Phe Asp Val Val Lys Cys Ile Leu Val
            100                 105                 110

Ala Ser Pro Gly Phe Val Arg Glu Gln Phe Cys Asp Tyr Met Phe Gln
        115                 120                 125

Gln Ala Val Lys Thr Asp Asn Lys Leu Leu Leu Glu Asn Arg Ser Lys
    130                 135                 140

Phe Leu Gln Val His Ala Ser Ser Gly His Lys Tyr Ser Leu Lys Glu
145                 150                 155                 160

Ala Leu Cys Asp Pro Thr Val Ala Ser Arg Leu Ser Asp Thr Lys Ala
                165                 170                 175

Ala Gly Glu Val Lys Ala Leu Asp Asp Phe Tyr Lys Met Leu Gln His
            180                 185                 190

Glu Pro Asp Arg Ala Phe Tyr Gly Leu Lys Gln Val Glu Lys Ala Asn
        195                 200                 205

Glu Ala Met Ala Ile Asp Thr Leu Leu Ile Ser Asp Glu Leu Phe Arg
    210                 215                 220

His Gln Asp Val Ala Thr Arg Ser Arg Tyr Val Arg Leu Val Asp Ser
225                 230                 235                 240

Val Lys Glu Asn Ala Gly Thr Val Arg Ile Phe Ser Ser Leu His Val
                245                 250                 255

Ser Gly Glu Gln Leu Ser Gln Leu Thr Gly Val Ala Ala Ile Leu Arg
            260                 265                 270

Phe Pro Val Pro Glu Leu Ser Asp Gln Glu Gly Asp Ser Ser Ser Glu
        275                 280                 285

Glu Asp 
    290



<210> 1936
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1936
Met Cys Trp Asp Arg Ala Trp Xaa Gln Gly Ser Xaa Ser Ala Pro Cys
  1               5                  10                  15

Trp Leu His Asp Xaa Gly Lys Ser Xaa Thr Asp Ile Cys Cys Asn Ala
             20                  25                  30

His Thr Gly Ile His Cys Arg Ile Ser Ile Leu Val Val Ile Val Asn
         35                  40                  45

Trp Phe Phe Met Gln Thr Glu Val Ile Ser Thr Leu Lys Ile Leu Ser
     50                  55                  60

Glu Leu Leu Asn Ser Gly Glu Leu Leu Cys Glu Trp Leu Gly Lys Ile
 65                  70                  75                  80

Glu Glu Asp Cys Ser Ala Gly Gln Ala Gln Phe Ile Arg Pro Arg Ser
                 85                  90                  95

Lys Tyr Asp Phe Tyr Pro His Thr Phe 
            100                 105



<210> 1937
<211> 133
<212> PRT
<213> Homo sapiens

<400> 1937
Met Phe Gly Asp Tyr Glu Ala Gln Arg His Trp Gln Glu Ile Thr Phe
  1               5                  10                  15

Asn Leu Pro Val Lys Gln Trp Tyr Phe Asn Ser Ser Asp Asn Asn Leu
             20                  25                  30

Gln Tyr Trp Gly Leu Asp Tyr Pro Pro Leu Thr Ala Tyr His Ser Leu
         35                  40                  45

Leu Cys Ala Tyr Val Ala Lys Phe Ile Asn Pro Asp Trp Ile Ala Leu
     50                  55                  60

His Thr Ser Arg Gly Tyr Glu Ser Gln Ala His Lys Leu Phe Met Arg
 65                  70                  75                  80

Thr Thr Val Leu Ile Ala Asp Leu Leu Ile Tyr Ile Pro Ala Val Val
                 85                  90                  95

Leu Tyr Cys Cys Cys Leu Lys Glu Ile Ser Thr Lys Lys Lys Ile Ala
            100                 105                 110

Asn Ala Leu Cys Ile Leu Leu Tyr Pro Gly Leu Ile Leu Ile Asp Tyr
        115                 120                 125

Gly Thr Phe Ser Ile 
    130



<210> 1938
<211> 203
<212> PRT
<213> Homo sapiens

<400> 1938
Met Glu Thr Ser Ala Ser Ser Ser Gln Pro Gln Asp Asn Ser Gln Val
  1               5                  10                  15

His Arg Glu Thr Glu Asp Val Asp Tyr Gly Glu Thr Asp Phe His Lys
             20                  25                  30

Gln Asp Gly Lys Ala Gly Leu Phe Ser Gln Glu Gln Tyr Glu Arg Asn
         35                  40                  45

Lys Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser
     50                  55                  60

Ser Ser Ser Ser Ser Ser Gly Pro Gly His Gly Glu Pro Asp Val Leu
 65                  70                  75                  80

Lys Asp Glu Leu Gln Leu Tyr Gly Asp Ala Pro Gly Glu Val Val Pro
                 85                  90                  95

Ser Gly Glu Ser Gly Leu Arg Arg Arg Gly Ser Asp Pro Ala Ser Gly
            100                 105                 110

Glu Val Glu Ala Ser Gln Leu Arg Arg Leu Asn Ile Lys Lys Asp Asp
        115                 120                 125

Glu Phe Phe His Phe Val Leu Leu Cys Phe Ala Ile Gly Ala Leu Leu
    130                 135                 140

Val Cys Tyr His Tyr Tyr Ala Asp Trp Phe Met Ser Leu Gly Val Gly
145                 150                 155                 160

Leu Leu Thr Phe Ala Ser Leu Glu Thr Val Gly Ile Tyr Phe Gly Leu
                165                 170                 175

Val Tyr Arg Ile His Ser Val Leu Gln Gly Phe Ile Pro Leu Phe Gln
            180                 185                 190

Lys Phe Arg Leu Thr Gly Phe Arg Lys Thr Asp 
        195                 200



<210> 1939
<211> 177
<212> PRT
<213> Homo sapiens

<400> 1939
Met Gln Gly Arg Leu His Leu Ser Ala Cys Pro Arg Ser Trp Ala Pro
  1               5                  10                  15

Leu Gly Pro Trp Leu Gly Ser Gly Pro Trp Leu Cys Thr Pro Thr Ile
             20                  25                  30

Pro Thr His Leu Ala Ser Pro Pro Ala Ala Pro Leu Thr Ala Ala Ala
         35                  40                  45

Pro Pro Pro Ser Ala Asp Ala Gln Ser Gly Ser Gly Gln Arg Ser Ser
     50                  55                  60

Pro Ala Pro Cys Ser Pro Ser Leu Lys Pro Pro Asn Leu Pro Thr Ala
 65                  70                  75                  80

Thr Leu His Thr Gly Gln Thr Lys Pro Arg Arg Glu Gly Trp Ala Gly
                 85                  90                  95

Ala Arg Leu Ile Leu Gly Arg Arg Glu His Thr Ser Thr Tyr Leu Gly
            100                 105                 110

Ala Gln Cys Pro Phe Leu Glu Phe Pro Thr Cys Val Ser His Ala Ser
        115                 120                 125

Val Gly Ser Leu Pro Pro Arg Leu Ala Thr Val Cys Asn Val Phe Met
    130                 135                 140

Tyr Val Phe Val Asn Val Ile Glu Val Trp Gly Gly Val Gly Gly Trp
145                 150                 155                 160

Arg Gln Met Leu Ala Arg Ser Ala Leu Pro Ile Gln Ala Pro Ser Pro
                165                 170                 175

Leu 




<210> 1940
<211> 227
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1940
Met Gln Ser Ser Gly Phe Asp Ala Leu Leu His Glu Ile Gln Glu Ile
  1               5                  10                  15

Arg Glu Thr Gln Ala Arg Leu Glu Glu Ser Phe Glu Thr Leu Lys Glu
             20                  25                  30

His Tyr Gln Arg Asp Tyr Ser Leu Ile Met Gln Thr Leu Gln Glu Glu
         35                  40                  45

Arg Tyr Arg Cys Glu Arg Leu Glu Glu Gln Leu Asn Asp Leu Thr Glu
     50                  55                  60

Leu His Gln Asn Glu Ile Leu Asn Leu Lys Gln Glu Leu Ala Ser Met
 65                  70                  75                  80

Glu Glu Lys Ile Ala Tyr Gln Ser Tyr Glu Arg Ala Arg Asp Ile Gln
                 85                  90                  95

Glu Ala Leu Glu Ala Cys Gln Thr Arg Ile Ser Lys Met Glu Leu Gln
            100                 105                 110

Gln Gln Gln Gln Gln Val Val Gln Leu Glu Xaa Leu Glu Asn Ala Thr
        115                 120                 125

Ala Arg Asn Leu Leu Gly Lys Leu Ile Asn Ile Leu Leu Ala Val Met
    130                 135                 140

Ala Val Leu Leu Val Phe Val Ser Thr Val Ala Asn Cys Val Val Pro
145                 150                 155                 160

Leu Met Lys Thr Arg Asn Arg Thr Phe Ser Thr Leu Phe Leu Val Val
                165                 170                 175

Phe Ile Ala Phe Leu Trp Lys His Trp Asp Ala Leu Phe Ser Tyr Val
            180                 185                 190

Gly Thr Val Leu Phe Ile Pro Leu Asp Asp Ala Gly Thr Glu Gly Ile
        195                 200                 205

Val Pro Tyr Pro Leu Gly Glu Cys Met Gln Gln Arg Val Arg Gln Gln
    210                 215                 220

Leu Thr Tyr 
225



<210> 1941
<211> 262
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (59)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1941
Met Phe Arg Trp Glu Arg Ser Ile Pro Leu Arg Gly Ser Ala Ala Ala
  1               5                  10                  15

Leu Cys Asn Asn Leu Ser Val Leu Gln Leu Pro Ala Arg Asn Leu Thr
             20                  25                  30

Tyr Phe Gly Val Val His Gly Pro Ser Ala Gln Leu Leu Ser Ala Ala
         35                  40                  45

Pro Glu Gly Val Pro Leu Ala Gln Arg Gln Xaa His Ala Lys Glu Gly
     50                  55                  60

Ala Gly Val Ser Pro Pro Leu Ile Thr Gln Val His Trp Cys Val Leu
 65                  70                  75                  80

Pro Phe Arg Val Leu Leu Val Leu Thr Ser His Arg Gly Ile Gln Met
                 85                  90                  95

Tyr Glu Ser Asn Gly Tyr Thr Met Val Tyr Trp His Ala Leu Asp Ser
            100                 105                 110

Gly Asp Ala Ser Pro Val Gln Ala Val Phe Ala Arg Gly Ile Ala Ala
        115                 120                 125

Ser Gly His Phe Ile Cys Val Gly Thr Trp Ser Gly Arg Val Leu Val
    130                 135                 140

Phe Asp Ile Pro Ala Lys Gly Pro Asn Ile Val Leu Ser Glu Glu Leu
145                 150                 155                 160

Ala Gly His Gln Met Pro Ile Thr Asp Ile Ala Thr Glu Pro Ala Gln
                165                 170                 175

Gly Gln Asp Cys Val Ala Asp Met Val Thr Ala Asp Asp Ser Gly Leu
            180                 185                 190

Leu Cys Val Trp Arg Ser Gly Pro Glu Phe Thr Leu Leu Thr Arg Ile
        195                 200                 205

Pro Gly Phe Gly Val Pro Cys Pro Ser Val Gln Leu Trp Gln Gly Ile
    210                 215                 220

Ile Ala Ala Gly Tyr Gly Asn Gly Gln Val His Leu Tyr Glu Ala Thr
225                 230                 235                 240

Thr Gly Asn Leu His Val Gln Ile Asn Ala His Ala Arg Ala His Leu
                245                 250                 255

Arg Pro Gly Pro Gly Phe 
            260



<210> 1942
<211> 315
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (312)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1942
Met Ala Ala Pro Met Glu Val Ala Val Cys Thr Asp Ser Ala Ala Pro
  1               5                  10                  15

Met Trp Ser Cys Ile Val Trp Glu Leu His Ser Gly Ala Asn Leu Leu
             20                  25                  30

Thr Tyr Arg Gly Gly Gln Ala Gly Pro Arg Gly Leu Ala Leu Leu Asn
         35                  40                  45

Gly Glu Tyr Leu Leu Ala Ala Gln Leu Gly Lys Asn Tyr Ile Ser Ala
     50                  55                  60

Trp Glu Leu Gln Arg Lys Asp Gln Leu Gln Gln Lys Ile Met Cys Pro
 65                  70                  75                  80

Gly Pro Val Thr Cys Leu Thr Ala Ser Pro Asn Gly Leu Tyr Val Leu
                 85                  90                  95

Ala Gly Val Ala Glu Ser Ile His Leu Trp Glu Val Ser Thr Gly Asn
            100                 105                 110

Leu Leu Val Ile Leu Ser Arg His Tyr Gln Asp Val Ser Cys Leu Gln
        115                 120                 125

Phe Thr Gly Asp Ser Ser His Phe Ile Ser Gly Gly Lys Asp Cys Leu
    130                 135                 140

Val Leu Val Trp Ser Leu Cys Ser Val Leu Xaa Ala Asp Pro Ser Arg
145                 150                 155                 160

Ile Pro Ala Pro Arg His Val Trp Ser His His Thr Leu Pro Ile Thr
                165                 170                 175

Asp Leu His Cys Gly Phe Gly Gly Pro Leu Ala Arg Val Ala Thr Ser
            180                 185                 190

Ser Leu Asp Gln Thr Val Lys Leu Trp Glu Val Ser Ser Gly Glu Leu
        195                 200                 205

Leu Leu Ser Val Leu Phe Asp Val Ser Ile Met Ala Val Thr Met Asp
    210                 215                 220

Leu Ala Glu His His Met Phe Cys Gly Gly Ser Glu Gly Ser Ile Phe
225                 230                 235                 240

Gln Val Asp Leu Phe Thr Trp Pro Gly Gln Arg Glu Arg Ser Phe His
                245                 250                 255

Pro Glu Gln Asp Ala Gly Lys Val Phe Lys Gly His Arg Asn Gln Val
            260                 265                 270

Thr Cys Leu Ser Val Ser Thr Asp Gly Ser Val Leu Leu Ser Gly Ser
        275                 280                 285

His Asp Glu Thr Val Arg Leu Trp Asp Val Gln Ser Lys Gln Cys Ile
    290                 295                 300

Arg Thr Val Ala Ser Lys Ala Xaa Ser Pro Met 
305                 310                 315



<210> 1943
<211> 242
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1943
Met Glu Glu Gln His Lys Cys Ser Ser Lys Ser Leu Glu His Lys Thr
  1               5                  10                  15

Gln Thr Pro Pro Val Glu Glu Asn Val Thr Gln Lys Ile Ser Asp Leu
             20                  25                  30

Glu Ile Cys Ala Asp Glu Phe Pro Gly Ser Ser Ala Thr Tyr Arg Ile
         35                  40                  45

Leu Glu Val Gly Cys Gly Val Gly Asn Thr Val Phe Pro Ile Leu Gln
     50                  55                  60

Thr Asn Asn Asp Pro Gly Leu Phe Val Tyr Cys Cys Asp Phe Ser Ser
 65                  70                  75                  80

Thr Ala Ile Glu Leu Val Gln Thr Asn Ser Glu Tyr Asp Pro Ser Arg
                 85                  90                  95

Cys Phe Ala Phe Val His Asp Leu Cys Asp Glu Glu Lys Ser Tyr Pro
            100                 105                 110

Val Pro Lys Gly Ser Leu Asp Ile Ile Ile Leu Ile Phe Val Leu Ser
        115                 120                 125

Ala Ile Val Pro Asp Lys Met Gln Lys Ala Ile Asn Arg Leu Ser Arg
    130                 135                 140

Leu Leu Lys Pro Gly Gly Met Xaa Leu Leu Arg Asp Tyr Gly Arg Tyr
145                 150                 155                 160

Asp Met Ala Gln Leu Arg Phe Lys Lys Gly Gln Cys Leu Ser Gly Asn
                165                 170                 175

Phe Tyr Val Arg Gly Asp Gly Thr Arg Val Tyr Phe Phe Thr Gln Glu
            180                 185                 190

Glu Leu Asp Thr Leu Phe Thr Thr Ala Gly Leu Glu Lys Val Gln Asn
        195                 200                 205

Leu Val Asp Arg Arg Leu Gln Val Asn Arg Gly Lys Gln Leu Thr Met
    210                 215                 220

Tyr Arg Val Trp Ile Gln Cys Lys Tyr Cys Lys Pro Leu Leu Ser Ser
225                 230                 235                 240

Thr Ser 




<210> 1944
<211> 105
<212> PRT
<213> Homo sapiens

<400> 1944
Met Ala Val Ala Glu Ser Gly Met Gly Ile Val Glu Asp Lys Val Ile
  1               5                  10                  15

Lys Asn His Phe Ala Ser Glu Tyr Ile Tyr Asn Ala Tyr Lys Asp Glu
             20                  25                  30

Lys Thr Cys Gly Val Leu Ser Glu Asp Asp Thr Phe Gly Thr Ile Thr
         35                  40                  45

Ile Ala Glu Pro Ile Gly Ile Ile Cys Gly Ile Val Pro Thr Thr Asn
     50                  55                  60

Pro Thr Ser Thr Ala Ile Phe Lys Ser Leu Ile Ser Leu Lys Thr Arg
 65                  70                  75                  80

Asn Ala Ile Ile Phe Ser Pro His Pro Arg Ala Lys Asp Ala Thr Asn
                 85                  90                  95

Lys Ala Ala Asp Ile Val Leu Gln Ala 
            100                 105



<210> 1945
<211> 415
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (352)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1945
Met Phe Val Ser His Xaa Glu Glu Val Asp Gly Cys Pro Val Ile Leu
  1               5                  10                  15

Val Cys Gly Ser Gln Asp Val Gly Lys Ser Thr Phe Asn Arg Tyr Leu
             20                  25                  30

Ile Asn His Leu Leu Asn Ser Leu Pro Cys Val Asp Tyr Leu Glu Cys
         35                  40                  45

Asp Leu Gly Gln Thr Glu Phe Thr Pro Pro Gly Cys Ile Ser Leu Leu
     50                  55                  60

Asn Ile Thr Glu Pro Val Leu Gly Pro Pro Phe Thr His Leu Arg Thr
 65                  70                  75                  80

Pro Gln Lys Met Val Tyr Tyr Gly Lys Pro Ser Cys Lys Asn Asn Tyr
                 85                  90                  95

Glu Asn Tyr Ile Asp Ile Val Lys Tyr Val Phe Ser Ala Tyr Lys Arg
            100                 105                 110

Glu Ser Pro Leu Ile Val Asn Thr Met Gly Trp Val Ser Asp Gln Gly
        115                 120                 125

Leu Leu Leu Leu Ile Asp Leu Ile Arg Leu Leu Ser Pro Ser His Val
    130                 135                 140

Val Gln Phe Arg Ser Asp His Ser Lys Tyr Met Pro Asp Leu Thr Pro
145                 150                 155                 160

Gln Tyr Val Asp Asp Met Asp Gly Leu Tyr Thr Lys Ser Lys Thr Lys
                165                 170                 175

Met Arg Asn Arg Arg Phe Arg Leu Ala Ala Phe Ala Asp Ala Leu Glu
            180                 185                 190

Phe Ala Asp Glu Glu Lys Glu Ser Pro Val Glu Phe Thr Gly His Lys
        195                 200                 205

Leu Ile Gly Val Tyr Thr Asp Phe Ala Phe Arg Ile Thr Pro Arg Asn
    210                 215                 220

Arg Glu Ser His Asn Lys Ile Leu Arg Asp Leu Ser Ile Leu Ser Tyr
225                 230                 235                 240

Leu Ser Gln Leu Gln Pro Pro Met Pro Lys Pro Leu Ser Pro Leu His
                245                 250                 255

Ser Leu Thr Pro Tyr Gln Val Pro Phe Asn Ala Val Ala Leu Arg Ile
            260                 265                 270

Thr His Ser Asp Val Ala Pro Thr His Ile Leu Tyr Ala Val Asn Ala
        275                 280                 285

Ser Trp Val Gly Leu Cys Lys Ile Gln Asp Asp Val Arg Gly Tyr Thr
    290                 295                 300

Asn Gly Pro Ile Leu Leu Ala Gln Thr Pro Ile Cys Asp Cys Leu Gly
305                 310                 315                 320

Phe Gly Ile Cys Arg Gly Ile Asp Met Glu Lys Arg Leu Tyr His Ile
                325                 330                 335

Leu Thr Pro Val Pro Pro Glu Glu Leu Arg Thr Val Asn Cys Leu Xaa
            340                 345                 350

Val Gly Ala Ile Ala Ile Pro His Cys Val Leu Lys Cys Gln Arg Gly
        355                 360                 365

Ile Glu Gly Thr Val Pro Tyr Val Thr Thr Asp Tyr Asn Phe Lys Leu
    370                 375                 380

Pro Gly Ala Ser Glu Lys Ile Gly Ala Arg Glu Pro Glu Glu Ala His
385                 390                 395                 400

Lys Glu Lys Pro Tyr Arg Arg Pro Lys Phe Cys Arg Lys Met Lys 
                405                 410                 415



<210> 1946
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1946
Met Pro Asp Ala Asn Pro Ser Ser Gly His Val Gln Pro Ala Gly Gln
  1               5                  10                  15

Pro Arg Gly Ser Leu Ser Ser Arg Ala Lys Asp Ser Arg Leu Pro Phe
             20                  25                  30

Ser Leu Leu Ala Phe Leu Leu Cys Pro Ala Val Ala Ala Gly Xaa Ala
         35                  40                  45

Ala Ala Ala Gly Gly Arg Arg Ser Cys Leu Ser Ala Pro Pro Cys Pro
     50                  55                  60

Thr Pro Ala Pro Ala Leu Glu Ile Trp Ser Pro Leu Glu Leu Ser Trp
 65                  70                  75                  80

Thr Gly Gly Gln Leu Arg Ala Cys Ala Leu Asn Ala Ala Leu Ser Arg
                 85                  90                  95

Gly Arg Glu Gln Asp Gly Glu Trp Lys Glu Ser Pro Pro Gly Phe Val
            100                 105                 110

Asn Cys Lys Lys Gly Pro Phe Gln Asp Asp Thr Arg Asn Arg Ala Arg
        115                 120                 125

Ala Leu Ala Gln Ser Leu Gly Ala Cys Leu Phe Phe Ile Ile Val Phe
    130                 135                 140

Lys Ser Leu 
145



<210> 1947
<211> 193
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (183)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1947
Met Ser Ile Leu Ile Ile Glu Ala Phe Tyr Gly Gly Ser His Lys Gln
  1               5                  10                  15

Leu Val Asp Leu Leu Gln Glu Glu Leu Gly Asp Cys Val Val Tyr Thr
             20                  25                  30

Leu Pro Ala Lys Lys Trp His Trp Arg Ala Arg Thr Ser Ala Leu Tyr
         35                  40                  45

Phe Ser Gln Thr Ile Pro Ile Ser Glu His Tyr Arg Thr Leu Phe Ala
     50                  55                  60

Ser Ser Val Leu Asn Leu Thr Glu Leu Ala Ala Leu Arg Pro Asp Leu
 65                  70                  75                  80

Gly Lys Leu Lys Lys Ile Leu Tyr Phe His Glu Asn Gln Leu Ile Tyr
                 85                  90                  95

Pro Val Lys Lys Cys Gln Glu Arg Asp Phe Gln Tyr Gly Tyr Asn Gln
            100                 105                 110

Ile Leu Ser Cys Leu Val Ala Asp Val Val Val Phe Asn Ser Val Phe
        115                 120                 125

Asn Met Glu Ser Phe Leu Thr Ser Met Gly Lys Phe Met Lys Leu Ile
    130                 135                 140

Pro Asp His Arg Pro Lys Asp Leu Glu Ser Ile Ile Arg Pro Lys Cys
145                 150                 155                 160

Gln Val Ile Tyr Phe Pro Ile Arg Phe Pro Asp Val Ser Arg Phe Met
                165                 170                 175

Pro Lys His Lys Thr Thr Xaa Leu Arg Arg Cys Ser Ala Xaa Lys Glu
            180                 185                 190

Met 




<210> 1948
<211> 128
<212> PRT
<213> Homo sapiens

<400> 1948
Met Phe Leu Arg Gly Arg Pro Ile Thr Met Tyr Ile Pro Ser Gly Ile
  1               5                  10                  15

Arg Ser Leu Glu Glu Leu Pro Ser Gly Pro Pro Pro Glu Thr Leu Ser
             20                  25                  30

Leu Asp Trp Val Tyr Gly Tyr Arg Gly Arg Asp Ser Arg Ser Asn Leu
         35                  40                  45

Phe Val Leu Arg Ser Gly Glu Val Val Tyr Phe Ile Ala Cys Val Val
     50                  55                  60

Val Leu Tyr Arg Pro Gly Gly Gly Pro Gly Gly Pro Gly Gly Gly Gly
 65                  70                  75                  80

Gln Arg His Tyr Arg Gly His Thr Asp Cys Val Arg Cys Leu Ala Val
                 85                  90                  95

His Pro Asp Gly Val Arg Val Ala Ser Gly Gln Thr Ala Gly Val Asp
            100                 105                 110

Lys Asp Gly Lys Pro Leu Gln Pro Val Val His Ile Trp Asp Ser Lys
        115                 120                 125






<210> 1949
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1949
Met His Glu Glu Glu Ile Tyr Thr Ser Leu Gln Trp Asp Ser Pro Ala
  1               5                  10                  15

Pro Asp Thr Tyr Gln Lys Cys Leu Ser Ser Asn Lys Cys Ser Gly Ala
             20                  25                  30

Cys Cys Leu Val Met Val Ile Ser Cys Val Phe Cys Met Gly Leu Leu
         35                  40                  45

Thr Xaa Ser Ile Phe Leu Gly Val Lys Leu Leu Gln Val Ser Thr Ile
     50                  55                  60

Ala Met Gln Gln Gln Glu Lys Leu Ile Gln Gln Glu Arg Ala Leu Leu
 65                  70                  75                  80

Asn Phe Thr Glu Trp Glu Xaa Lys Leu Cys Pro Ser Xaa Glu Ile Leu
                 85                  90                  95

Pro Ser Leu His Ala Lys Leu Ile Lys Phe Ser Pro 
            100                 105



<210> 1950
<211> 117
<212> PRT
<213> Homo sapiens

<400> 1950
Met Ser Arg Lys Pro Glu Leu Cys Leu Gln Pro Ser Phe Ala His Cys
  1               5                  10                  15

Gln Ile Phe Pro Ser Ile Leu Gln Lys Cys Lys Ser Pro Ala Ser Ser
             20                  25                  30

Pro Gln Ala Val Pro Gly Val Trp Arg Ala Phe Thr Leu Pro Gly Gln
         35                  40                  45

Ala Cys Leu Gly Thr Gly Leu Trp Pro Gly Leu Pro Ala Leu Leu Gln
     50                  55                  60

Trp Pro Ser Pro Ser Pro Pro Met Glu Glu Trp Pro Arg Thr His Ile
 65                  70                  75                  80

Leu Pro Met Leu Val Gly Ala Val Ala Gly Ala Val Ala Ala Ser Arg
                 85                  90                  95

Thr Gly Gly Tyr Leu Phe Thr Gln Arg Thr Leu Val Pro Gly Leu His
            100                 105                 110

Val Leu Leu Ala Leu 
        115



<210> 1951
<211> 227
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1951
Met Ala Leu Val Arg Gly Gly Trp Leu Trp Arg Gln Ser Ser Ile Leu
  1               5                  10                  15

Arg Arg Trp Lys Arg Asn Trp Phe Ala Leu Trp Leu Asp Gly Thr Leu
             20                  25                  30

Gly Tyr Tyr His Asp Glu Thr Ala Gln Asp Glu Glu Asp Arg Val Leu
         35                  40                  45

Ile His Phe Asn Val Arg Asp Ile Lys Ile Gly Pro Glu Cys His Asp
     50                  55                  60

Val Gln Pro Pro Glu Gly Arg Ser Arg Asp Gly Leu Leu Thr Val Asn
 65                  70                  75                  80

Leu Arg Glu Gly Gly Arg Leu His Leu Cys Ala Glu Thr Lys Asp Asp
                 85                  90                  95

Ala Leu Ala Trp Lys Thr Ala Leu Leu Glu Ala Asn Ser Thr Pro Val
            100                 105                 110

Arg Val Tyr Ser Pro Tyr Gln Asp Tyr Tyr Glu Val Val Pro Pro Asn
        115                 120                 125

Ala His Glu Ala Thr Tyr Val Arg Ser Tyr Tyr Gly Pro Pro Tyr Ala
    130                 135                 140

Gly Pro Gly Val Thr His Val Ile Val Arg Glu Asp Pro Cys Tyr Ser
145                 150                 155                 160

Ala Gly Ala Pro Leu Ala Met Gly Met Leu Ala Gly Xaa Pro Leu Gly
                165                 170                 175

Gly Xaa Gly Leu Ala His Val Val Ala Leu Leu Val Leu Ser Pro Gly
            180                 185                 190

Thr Arg Ser Thr Asp Pro Cys Ala Trp Ile Ala Arg Leu Leu Phe Leu
        195                 200                 205

Leu Asp Pro Ile Leu Tyr His Pro Ser Pro Val Pro Leu Trp Pro Tyr
    210                 215                 220

Pro Leu His 
225



<210> 1952
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1952
Met Ala Ala Ala Ala Ala Ala Ala Gly Ala Ala Gly Ser Ala Ala Pro
  1               5                  10                  15

Ala Ala Ala Ala Gly Ala Pro Gly Ser Gly Gly Ala Pro Ser Gly Ser
             20                  25                  30

Gln Gly Val Leu Ile Gly Asp Arg Leu Tyr Ser Gly Val Leu Ile Thr
         35                  40                  45

Leu Glu Asn Cys Leu Leu Pro Asp Asp Lys Leu Arg Phe Thr Pro Ser
     50                  55                  60

Met Ser Ser Gly Leu Asp Thr Asp Thr Glu Thr Asp Leu Arg Val Val
 65                  70                  75                  80

Gly Cys Glu Leu Ile Gln Ala Ala Gly Ile Leu Leu Arg Leu Pro Xaa
                 85                  90                  95

Val Ala Met Ala Thr Gly Xaa Val Leu Phe Gln Arg Phe Phe Tyr Thr
            100                 105                 110

Lys Ser Phe Val Lys His Ser Met Glu His Val Ser Met Ala Cys Val
        115                 120                 125

His Leu Ala Ser Arg Xaa Xaa Xaa Pro Gln Asp Ala Tyr Gly Thr Ser
    130                 135                 140

Ser Met Val Asn Ala Leu Thr Val Arg Asp Lys Arg Xaa Pro Ala Leu
145                 150                 155                 160

Ile Trp Ile Arg Tyr Val Ile Lys Thr Xaa 
                165                 170



<210> 1953
<211> 119
<212> PRT
<213> Homo sapiens

<400> 1953
Met Gly Ile Ser Leu Cys Phe Pro Gly Ala Ala Ala Ser Trp Val Arg
  1               5                  10                  15

Asp Val Ala Leu Pro His Gly Ser Gly Gly Gly Val Val Pro Arg Arg
             20                  25                  30

Lys Pro Pro Gly Cys Trp Asp Gln Lys Met Gly Arg Asp Ala Arg Trp
         35                  40                  45

Glu His Leu Phe Pro Leu Cys Trp Cys Leu Asp Pro Arg Leu Glu Gly
     50                  55                  60

Phe Ala Phe Pro Gln Val Leu Gly Pro Arg Gly Ala Pro Leu Ala His
 65                  70                  75                  80

Gly Leu Leu Ala Val Ala Leu Gly Leu Ser Met Ser Asp Leu Arg Ile
                 85                  90                  95

Leu Ala Pro Ile Leu Pro Pro Trp Glu Ala Phe Leu Asp Leu Phe Gln
            100                 105                 110

Leu Ser Leu Trp Met Ser Leu 
        115



<210> 1954
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1954
Met Pro Asn Ala Gly Val Ser Gln Ser Phe Glu Trp Ser Val Cys Thr
  1               5                  10                  15

Glu Phe Val Val Leu Pro Leu Trp Phe Ser Pro Ser Gly Ile Phe Pro
             20                  25                  30

Ser Leu Ser Ser Trp Phe Gly Ser His Glu Tyr Cys Leu Leu Cys Val
         35                  40                  45

Ser Ser Thr Lys Lys Thr Ala Xaa Phe Tyr Pro Glu Tyr Leu Leu Ser
     50                  55                  60

Asp Trp Xaa Leu Ser Leu Trp Gly Ile Cys Lys Cys Pro Xaa Gly Gly
 65                  70                  75                  80

Asn Gly Xaa Ile Cys Trp Xaa His Phe Xaa Xaa Pro Pro Ser Leu Thr
                 85                  90                  95

Gly Phe Cys Leu Leu Gln Cys Cys Leu Pro Lys Leu Ile Ser Ile Val
            100                 105                 110

Leu Lys Gln Xaa Xaa Leu Trp Phe Asn Pro Xaa Phe Val Val Val Leu
        115                 120                 125

Ser Lys Gly Asp Trp Ser Xaa Thr Ser 
    130                 135



<210> 1955
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1955
Met Val Ile Pro Gln Lys His Tyr Ile Leu Gly Val Val Thr Ala Met
  1               5                  10                  15

Val Gly Xaa Phe Ala Ile Gly Ala Ala Phe Gly Leu Ile Tyr Leu Tyr
             20                  25                  30

Thr Ala Glu Leu Tyr Pro Thr Ile Val Arg Ser Leu Ala Val Gly Ser
         35                  40                  45

Gly Thr Met Val Cys Arg Leu Ala Ser Ile Leu Ala Pro Phe Ser Val
     50                  55                  60

Asp Val Ser Ser Ile Trp Ile Phe Ile Pro Gln Leu Xaa Val Gly Thr
 65                  70                  75                  80

Met Ala Ser Leu Ser Glu Cys Tyr Thr Xaa Leu Pro Glu Pro Xaa Gly
                 85                  90                  95

Thr Ala Ser Thr Thr Trp Arg Ser Cys Lys Leu Ser Arg Asp Glu Arg
            100                 105                 110

Ala Ser Asn His Pro His Tyr Ile Leu Leu Lys Lys Thr Ile Pro Xaa
        115                 120                 125

Ser Ala Gly Ile Ser His Thr Ala Ser Leu Asp Ile Phe Pro Met 
    130                 135                 140



<210> 1956
<211> 176
<212> PRT
<213> Homo sapiens

<400> 1956
Met Glu Gln Arg Leu Ala Glu Phe Arg Ala Ala Arg Lys Arg Ala Gly
  1               5                  10                  15

Leu Ala Ala Gln Pro Pro Ala Ala Ser Gln Gly Ala Gln Thr Pro Gly
             20                  25                  30

Glu Lys Ala Glu Ala Ala Ala Thr Leu Lys Ala Ala Pro Gly Trp Leu
         35                  40                  45

Lys Arg Phe Leu Val Trp Lys Pro Arg Pro Ala Ser Ala Arg Ala Gln
     50                  55                  60

Pro Gly Leu Val Gln Glu Ala Ala Gln Pro Gln Gly Ser Thr Ser Glu
 65                  70                  75                  80

Thr Pro Trp Asn Thr Ala Ile Pro Leu Pro Ser Cys Trp Asp Gln Ser
                 85                  90                  95

Phe Leu Thr Asn Ile Thr Phe Leu Lys Val Leu Leu Trp Leu Val Leu
            100                 105                 110

Leu Gly Leu Phe Val Glu Leu Glu Phe Gly Leu Ala Tyr Phe Val Leu
        115                 120                 125

Ser Leu Phe Tyr Trp Met Tyr Val Gly Thr Arg Gly Pro Glu Glu Lys
    130                 135                 140

Lys Glu Gly Glu Lys Ser Ala Tyr Ser Val Phe Asn Pro Gly Cys Glu
145                 150                 155                 160

Ala Ile Gln Gly Thr Leu Thr Ala Glu His Trp Ser Ala Ser Tyr Ser
                165                 170                 175






<210> 1957
<211> 131
<212> PRT
<213> Homo sapiens

<400> 1957
Met Ala Gly Ile Lys Ala Leu Ile Ser Leu Ser Phe Gly Gly Ala Ile
  1               5                  10                  15

Gly Leu Met Phe Leu Met Leu Gly Cys Ala Leu Pro Ile Tyr Asn Lys
             20                  25                  30

Tyr Trp Pro Leu Phe Val Leu Phe Phe Tyr Ile Leu Ser Pro Ile Pro
         35                  40                  45

Tyr Cys Ile Ala Arg Arg Leu Val Asp Asp Thr Asp Ala Met Ser Asn
     50                  55                  60

Ala Cys Lys Glu Leu Ala Ile Phe Leu Thr Thr Gly Ile Val Val Ser
 65                  70                  75                  80

Ala Phe Gly Leu Pro Ile Val Phe Ala Arg Ala His Leu Ile Glu Trp
                 85                  90                  95

Gly Ala Cys Ala Leu Val Leu Thr Gly Asn Thr Val Ile Phe Ala Thr
            100                 105                 110

Ile Leu Gly Phe Phe Leu Val Phe Gly Ser Asn Asp Asp Phe Ser Trp
        115                 120                 125

Gln Gln Trp 
    130



<210> 1958
<211> 406
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (254)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1958
Met Gly Ala Ala Ser Arg Val Gly Val Pro Glu Pro Gly Gln Leu His
  1               5                  10                  15

Phe Asn Gln Cys Leu Thr Ala Glu Glu Ile Phe Ser Leu His Gly Phe
             20                  25                  30

Ser Asn Ala Thr Gln Ile Thr Ser Ser Lys Phe Ser Val Ile Cys Pro
         35                  40                  45

Ala Val Leu Gln Gln Leu Asn Phe His Pro Cys Glu Asp Arg Pro Lys
     50                  55                  60

His Lys Thr Arg Pro Ser His Ser Glu Val Trp Gly Tyr Gly Phe Leu
 65                  70                  75                  80

Ser Val Thr Ile Ile Asn Leu Ala Ser Leu Leu Gly Leu Ile Leu Thr
                 85                  90                  95

Pro Leu Ile Lys Lys Ser Tyr Phe Pro Lys Ile Leu Thr Phe Phe Val
            100                 105                 110

Gly Leu Ala Ile Gly Thr Leu Phe Ser Asn Ala Ile Phe Gln Leu Ile
        115                 120                 125

Pro Glu Ala Phe Gly Phe Asp Pro Lys Val Asp Ser Tyr Val Glu Lys
    130                 135                 140

Ala Val Ala Val Phe Gly Gly Phe Tyr Leu Leu Phe Phe Phe Glu Arg
145                 150                 155                 160

Met Leu Lys Met Leu Leu Lys Thr Tyr Gly Gln Asn Gly His Thr His
                165                 170                 175

Phe Gly Asn Asp Asn Phe Gly Pro Gln Glu Lys Thr His Gln Pro Lys
            180                 185                 190

Ala Leu Pro Ala Ile Asn Gly Val Thr Cys Tyr Ala Asn Pro Ala Val
        195                 200                 205

Thr Glu Ala Asn Gly His Ile His Phe Asp Asn Val Ser Val Val Ser
    210                 215                 220

Leu Gln Asp Gly Lys Lys Glu Pro Ser Ser Cys Thr Cys Leu Lys Gly
225                 230                 235                 240

Pro Lys Leu Ser Glu Ile Gly Thr Ile Ala Trp Met Ile Xaa Leu Cys
                245                 250                 255

Asp Ala Leu His Asn Phe Ile Asp Gly Leu Ala Ile Gly Ala Ser Cys
            260                 265                 270

Thr Leu Ser Leu Leu Gln Gly Leu Ser Thr Ser Ile Ala Ile Leu Cys
        275                 280                 285

Glu Glu Phe Pro His Glu Leu Gly Asp Phe Val Ile Leu Leu Asn Ala
    290                 295                 300

Gly Met Ser Thr Arg Gln Ala Leu Leu Phe Asn Phe Leu Ser Ala Cys
305                 310                 315                 320

Ser Cys Tyr Val Gly Leu Ala Phe Gly Ile Leu Val Gly Asn Asn Phe
                325                 330                 335

Ala Pro Asn Ile Ile Phe Ala Leu Ala Gly Gly Met Phe Leu Tyr Ile
            340                 345                 350

Ser Leu Ala Asp Met Phe Pro Glu Met Asn Asp Met Leu Arg Glu Lys
        355                 360                 365

Val Thr Gly Arg Lys Thr Asp Phe Thr Phe Phe Met Ile Gln Asn Ala
    370                 375                 380

Gly Met Leu Thr Gly Phe Thr Ala Ile Leu Leu Ile Thr Leu Tyr Ala
385                 390                 395                 400

Gly Glu Ile Glu Leu Glu 
                405



<210> 1959
<211> 230
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1959
Met Leu Arg Phe Asn Gly Tyr Arg Glu Asn Pro Asn Leu Gln Glu Asp
  1               5                  10                  15

Ser Leu Met Lys Thr Gln Ala Xaa Cys Cys Trp Ser Val Cys Arg Arg
             20                  25                  30

Trp Gly Arg Pro Lys Arg Ser Xaa Arg Gln Val Ser Gln Gln Pro Val
         35                  40                  45

Gly Ala Leu Ala Ser Glu Gln Leu Pro Glu Gly Asp Ser Gly Gly Ala
     50                  55                  60

Val Cys Ser Arg Leu Leu Ser Arg Arg Pro Gln Glu Glu Leu Glu Pro
 65                  70                  75                  80

Gly Ile His Lys Ser Pro Gly Glu Gly Ser Gln Val Leu Val His Trp
                 85                  90                  95

Leu Leu Gly Asn Ser Glu Val Phe Ala Ala Phe Cys Arg Ala Leu Pro
            100                 105                 110

Ala Gly Leu Leu Thr Leu Val Thr Ser Arg His Pro Ala Leu Ser Pro
        115                 120                 125

Val Tyr Leu Gly Leu Leu Thr Asp Trp Gly Gln Arg Leu His Tyr Asp
    130                 135                 140

Leu Gln Lys Gly Ile Trp Val Gly Thr Glu Ser Gln Asp Val Pro Xaa
145                 150                 155                 160

Glu Glu Leu His Asn Arg Phe Gln Ser Leu Cys Gln Ala Pro Pro Pro
                165                 170                 175

Leu Lys Asp Lys Val Leu Thr Ala Leu Glu Thr Cys Lys Ala Gln Asp
            180                 185                 190

Gly Asp Phe Glu Val Pro Gly Leu Ser Ile Trp Thr Asp Leu Leu Leu
        195                 200                 205

Ala Leu Arg Ser Gly Ala Phe Arg Lys Arg Gln Val Leu Gly Leu Ser
    210                 215                 220

Ala Gly Leu Ser Ser Val 
225                 230



<210> 1960
<211> 132
<212> PRT
<213> Homo sapiens

<400> 1960
Met Ala Gly Ser Arg Leu Pro Arg Gln Leu Phe Leu Gln Gly Val Ala
  1               5                  10                  15

Ala Val Phe Met Phe Ala Phe Ala Ser Leu Tyr Thr Gln Ile Pro Gly
             20                  25                  30

Leu Tyr Gly Pro Glu Gly Ile Leu Pro Ala Arg Arg Thr Leu Arg Pro
         35                  40                  45

Gln Gly Lys Gly Arg Trp Gln Gln Leu Trp Glu Thr Pro Thr Leu Leu
     50                  55                  60

Trp Glu Ala Pro Arg Leu Gly Leu Asp Thr Ala Gln Gly Leu Glu Leu
 65                  70                  75                  80

Leu Ser Leu Leu Gly Ala Leu Val Ala Leu Gly Ala Leu Leu Leu Ser
                 85                  90                  95

Pro Leu Arg His Pro Val Ile Tyr Leu Leu Leu Trp Ala Ala Thr Cys
            100                 105                 110

Ser Leu Pro Gly Gly Gln Val Ser Phe Ile Ser Gly Gly Leu Pro Ala
        115                 120                 125

Ala Arg Asp Trp 
    130



<210> 1961
<211> 129
<212> PRT
<213> Homo sapiens

<400> 1961
Met Gln Leu Leu Tyr Tyr Gln Ala Pro Met Ser Ser Ala Met Leu Leu
  1               5                  10                  15

Val Ala Val Pro Phe Phe Glu Pro Val Phe Gly Glu Gly Gly Ile Phe
             20                  25                  30

Gly Pro Trp Ser Val Ser Ala Leu Leu Met Val Leu Leu Ser Gly Val
         35                  40                  45

Ile Ala Phe Met Val Asn Leu Ser Ile Tyr Trp Ile Ile Gly Asn Thr
     50                  55                  60

Ser Pro Val Thr Tyr Asn Met Phe Gly His Phe Lys Phe Cys Ile Thr
 65                  70                  75                  80

Leu Phe Gly Gly Tyr Val Leu Phe Lys Asp Pro Leu Ser Ile Asn Gln
                 85                  90                  95

Ala Leu Gly Ile Leu Cys Thr Leu Phe Gly Ile Leu Ala Tyr Thr His
            100                 105                 110

Phe Lys Leu Ser Glu Gln Glu Gly Ser Arg Ser Lys Leu Ala Gln Arg
        115                 120                 125

Pro 




<210> 1962
<211> 366
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1962
Met Glu Asp Glu Glu Glu Glu Glu Leu Thr Met Glu Met Phe Gly Asn
  1               5                  10                  15

Ser Ser Ile Lys Phe Glu Leu Asp Ile Glu Pro Lys Val Phe Lys Pro
             20                  25                  30

Pro Ser Ser Thr Glu Ala Leu Asn Asp Ser Gln Glu Phe Pro Phe Pro
         35                  40                  45

Glu Thr Pro Thr Lys Val Trp Pro Gln Asp Glu Tyr Ile Val Glu Tyr
     50                  55                  60

Ser Leu Glu Tyr Gly Phe Leu Arg Leu Ser Gln Ala Thr Arg Gln Arg
 65                  70                  75                  80

Leu Ser Ile Pro Val Met Val Val Thr Leu Gly Glu Ser Glu Leu Leu
                 85                  90                  95

Gly Leu Gly Ser Ser Met Ala Gly Pro Pro Leu Leu Pro Arg Val Ser
            100                 105                 110

Ser Cys Trp Cys Gly Xaa Gly Gly Cys Ala Gly Ser Thr Gly Val Cys
        115                 120                 125

Pro Ala Pro Gly Thr Leu Pro Arg Ala Gly Val Leu Asp Gly Phe Pro
    130                 135                 140

Lys Asn Gly Gln Gly Arg Lys Gln Ala Arg Pro Gln Gln Trp Ser Gln
145                 150                 155                 160

Leu Gly Gln Gly Pro Gly Gly Gly Leu Gly Gly Ala Pro Gly Ser Leu
                165                 170                 175

Ile His Pro Pro Ala Asp Pro Thr Arg Asp Gln Cys Phe Gly Asp Arg
            180                 185                 190

Phe Ser Arg Leu Leu Leu Asp Glu Phe Leu Gly Tyr Asp Asp Ile Leu
        195                 200                 205

Met Ser Ser Val Lys Gly Leu Ala Glu Asn Glu Glu Asn Lys Gly Phe
    210                 215                 220

Leu Arg Asn Val Val Ser Gly Glu His Tyr Arg Phe Val Ser Met Trp
225                 230                 235                 240

Met Ala Arg Thr Ser Tyr Leu Ala Ala Phe Ala Ile Met Val Ile Phe
                245                 250                 255

Thr Leu Ser Val Ser Met Leu Leu Arg Tyr Ser His His Gln Ile Phe
            260                 265                 270

Val Phe Ile Ala Pro Leu Leu Thr Val Ile Leu Ala Leu Val Gly Met
        275                 280                 285

Glu Ala Ile Met Ser Glu Phe Phe Asn Asp Thr Thr Thr Ala Phe Tyr
    290                 295                 300

Ile Ile Leu Ile Val Trp Leu Ala Asp Gln Tyr Asp Ala Ile Cys Cys
305                 310                 315                 320

His Thr Ser Thr Ser Lys Arg His Trp Leu Arg Phe Phe Tyr Leu Tyr
                325                 330                 335

His Phe Ala Phe Tyr Ala Tyr His Tyr Arg Phe Asn Gly Gln Tyr Ser
            340                 345                 350

Ser Leu Ala Leu Ala Pro Ser Gly Ser Ser Ser Ser Ile Pro 
        355                 360                 365



<210> 1963
<211> 985
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (185)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (334)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (963)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1963
Met Thr Gln Gln Asp Ser His Ala Pro Leu Arg Asp Ser Arg Gly Ser
  1               5                  10                  15

Ser Phe Glu Met Thr Asp Asp Asp Ser Xaa Ile Arg Ala Leu Thr Gln
             20                  25                  30

Phe Pro Leu Pro Lys Asn Leu Leu Ala Lys Val Ile Gln Ile Ala Thr
         35                  40                  45

Ser Ser Ser Thr Ala Lys Asn Leu Met Gln Phe His Thr Val Gly Thr
     50                  55                  60

Lys Thr Lys Leu Ser Thr Leu Thr Leu Leu Trp Pro Cys Pro Met Thr
 65                  70                  75                  80

Phe Val Ala Lys Gly Arg Arg Lys Ala Glu Ala Glu Asn Lys Ala Ala
                 85                  90                  95

Ala Leu Ala Cys Lys Lys Leu Lys Ser Leu Gly Leu Val Asp Arg Asn
            100                 105                 110

Asn Glu Pro Leu Thr His Ala Met Tyr Asn Leu Ala Ser Leu Arg Glu
        115                 120                 125

Leu Gly Glu Thr Gln Arg Arg Pro Cys Thr Ile Gln Val Pro Glu Pro
    130                 135                 140

Ile Leu Arg Lys Ile Glu Thr Phe Leu Asn His Tyr Pro Val Glu Ser
145                 150                 155                 160

Ser Trp Ile Ala Pro Glu Leu Arg Leu Gln Ser Asp Asp Ile Leu Pro
                165                 170                 175

Leu Gly Lys Asp Ser Gly Pro Leu Xaa Asp Pro Ile Thr Gly Lys Pro
            180                 185                 190

Tyr Val Pro Leu Leu Glu Ala Glu Glu Val Arg Leu Ser Gln Ser Leu
        195                 200                 205

Leu Glu Leu Trp Arg Arg Arg Gly Pro Val Trp Gln Glu Ala Pro Gln
    210                 215                 220

Leu Pro Val Asp Pro His Arg Asp Thr Ile Leu Asn Ala Ile Glu Gln
225                 230                 235                 240

His Pro Val Val Val Ile Ser Gly Asp Thr Gly Cys Gly Lys Thr Thr
                245                 250                 255

Arg Ile Pro Gln Leu Leu Leu Glu Arg Tyr Val Thr Glu Gly Arg Gly
            260                 265                 270

Ala Arg Cys Asn Val Ile Ile Thr Gln Pro Arg Arg Ile Ser Ala Val
        275                 280                 285

Ser Val Ala Gln Arg Val Ser His Glu Leu Gly Pro Ser Leu Arg Arg
    290                 295                 300

Asn Val Gly Phe Gln Val Arg Leu Glu Ser Lys Pro Pro Ser Arg Gly
305                 310                 315                 320

Gly Ala Leu Leu Phe Cys Thr Val Gly Ile Leu Leu Arg Xaa Leu Gln
                325                 330                 335

Ser Asn Pro Ser Leu Glu Gly Val Ser His Val Ile Val Asp Glu Val
            340                 345                 350

His Glu Arg Asp Val Asn Thr Asp Phe Leu Leu Ile Leu Leu Lys Gly
        355                 360                 365

Leu Gln Arg Leu Asn Pro Ala Leu Arg Leu Val Leu Met Ser Ala Thr
    370                 375                 380

Gly Asp Asn Glu Arg Phe Ser Arg Tyr Phe Gly Gly Cys Pro Val Ile
385                 390                 395                 400

Lys Val Pro Gly Phe Met Tyr Pro Val Lys Glu His Tyr Leu Glu Asp
                405                 410                 415

Ile Leu Ala Lys Leu Gly Lys His Gln Tyr Leu His Arg His Arg His
            420                 425                 430

His Glu Ser Glu Asp Glu Cys Ala Leu Asp Leu Asp Leu Val Thr Asp
        435                 440                 445

Leu Val Leu His Ile Asp Ala Arg Gly Glu Pro Gly Gly Ile Leu Cys
    450                 455                 460

Phe Leu Pro Gly Trp Gln Glu Ile Lys Gly Val Gln Gln Arg Leu Gln
465                 470                 475                 480

Glu Ala Leu Gly Met His Glu Ser Lys Tyr Leu Ile Leu Pro Val His
                485                 490                 495

Ser Asn Ile Pro Met Met Asp Gln Lys Ala Ile Phe Gln Gln Pro Pro
            500                 505                 510

Val Gly Val Arg Lys Ile Val Leu Ala Thr Asn Ile Ala Glu Thr Ser
        515                 520                 525

Ile Thr Ile Asn Asp Ile Val His Val Val Asp Ser Gly Leu His Lys
    530                 535                 540

Glu Glu Arg Tyr Asp Leu Lys Thr Lys Val Ser Cys Leu Glu Thr Val
545                 550                 555                 560

Trp Val Ser Arg Ala Asn Val Ile Gln Arg Arg Gly Arg Ala Gly Arg
                565                 570                 575

Cys Gln Ser Gly Phe Ala Tyr His Leu Phe Pro Arg Ser Arg Leu Glu
            580                 585                 590

Lys Met Val Pro Phe Gln Val Pro Glu Ile Leu Arg Thr Pro Leu Glu
        595                 600                 605

Asn Leu Val Leu Gln Ala Lys Ile His Met Pro Glu Lys Thr Ala Val
    610                 615                 620

Glu Phe Leu Ser Lys Ala Val Asp Ser Pro Asn Ile Lys Ala Val Asp
625                 630                 635                 640

Glu Ala Val Ile Leu Leu Gln Glu Ile Gly Val Leu Asp Gln Arg Glu
                645                 650                 655

Tyr Leu Thr Thr Leu Gly Gln Arg Leu Ala His Ile Ser Thr Asp Pro
            660                 665                 670

Arg Leu Ala Lys Ala Ile Val Leu Ala Ala Ile Phe Arg Cys Leu His
        675                 680                 685

Pro Leu Leu Val Val Val Ser Cys Leu Thr Arg Asp Pro Phe Ser Ser
    690                 695                 700

Ser Leu Gln Asn Arg Ala Glu Val Asp Lys Val Lys Ala Leu Leu Ser
705                 710                 715                 720

His Asp Ser Gly Ser Asp His Leu Ala Phe Val Arg Ala Val Ala Gly
                725                 730                 735

Trp Glu Glu Val Leu Arg Trp Gln Asp Arg Ser Ser Arg Glu Asn Tyr
            740                 745                 750

Leu Glu Glu Asn Leu Leu Tyr Ala Pro Ser Leu Arg Phe Ile His Gly
        755                 760                 765

Leu Ile Lys Gln Phe Ser Glu Asn Ile Tyr Glu Ala Phe Leu Val Gly
    770                 775                 780

Lys Pro Ser Asp Cys Thr Leu Ala Ser Ala Gln Cys Asn Glu Tyr Ser
785                 790                 795                 800

Glu Glu Glu Glu Leu Val Lys Gly Val Leu Met Ala Gly Leu Tyr Pro
                805                 810                 815

Asn Leu Ile Gln Val Arg Gln Gly Lys Val Thr Arg Gln Gly Lys Phe
            820                 825                 830

Lys Pro Asn Ser Val Thr Tyr Arg Thr Lys Ser Gly Asn Ile Leu Leu
        835                 840                 845

His Lys Ser Thr Ile Asn Arg Glu Ala Thr Arg Leu Arg Ser Arg Trp
    850                 855                 860

Leu Thr Tyr Phe Met Ala Val Lys Ser Asn Gly Ser Val Phe Val Arg
865                 870                 875                 880

Asp Ser Ser Gln Val His Pro Leu Ala Val Leu Leu Leu Thr Asp Gly
                885                 890                 895

Asp Val His Ile Arg Asp Asp Gly Arg Arg Ala Thr Ile Ser Leu Ser
            900                 905                 910

Asp Ser Asp Leu Leu Arg Leu Glu Gly Asp Ser Arg Thr Val Arg Leu
        915                 920                 925

Leu Lys Glu Leu Arg Arg Ala Leu Gly Arg Met Val Glu Arg Ser Leu
    930                 935                 940

Arg Ser Glu Leu Ala Ala Leu Pro Pro Ser Val Gln Glu Glu His Gly
945                 950                 955                 960

Gln Leu Xaa Ala Leu Leu Ala Glu Leu Leu Arg Gly Pro Cys Gly Ser
                965                 970                 975

Phe Asp Val Arg Lys Thr Ala Asp Asp 
            980                 985



<210> 1964
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1964
Met Lys Val Phe Cys Glu Val Leu Glu Glu Leu Tyr Lys Lys Val Leu
  1               5                  10                  15

Leu Gly Ala Thr Leu Glu Asn Asp Ser His Asp Tyr Xaa Phe Tyr Leu
             20                  25                  30

Asn Pro Ala Val Ser Asp Gln Asp Cys Ser Thr Ala Thr Ser Leu Glu
         35                  40                  45

Trp Ala Asn Thr Cys Gly Ile Gln Gly Arg His Gln Pro Ile Ser Val
     50                  55                  60

Gly Val Ala Pro Ile Ala Val Ala Pro Val Cys Leu Lys Thr Asn Ser
 65                  70                  75                  80

Gln Met Ser Gly Ser Arg Glu Val Met Leu Leu Gln Leu Thr Val Ile
                 85                  90                  95

Lys Val Met Thr Thr Arg Ile Leu Ser Val Lys Thr Glu Phe His Ala
            100                 105                 110

Lys Glu Gln Tyr Arg Asp Val Ile Lys Ile Leu Leu Glu Ser Ala Lys
        115                 120                 125

Val Asp Ser Lys Leu Ile Cys Met Phe Gln Asn Ser Asp Lys Leu Leu
    130                 135                 140

Ser His Met Ala Ala Gln Cys Leu Ala Leu Leu Leu Tyr Phe Gln Leu
145                 150                 155                 160

Arg Glu Lys Ile Thr Leu Ser Asn Ser Trp Ile Ala Phe Cys Gln Lys
                165                 170                 175

Asn Leu Ser Glu Tyr Ser Glu Ser Asn Lys Ala Ile Tyr Cys Leu Trp
            180                 185                 190

Thr Leu Thr Ala Ile Ile Lys Gly Asn Leu 
        195                 200



<210> 1965
<211> 446
<212> PRT
<213> Homo sapiens

<400> 1965
Met Glu Ala Glu Ala Ala Asp Ala Pro Pro Gly Gly Val Glu Ser Ala
  1               5                  10                  15

Leu Ser Cys Phe Ser Phe Asn Gln Asp Cys Thr Ser Leu Ala Ile Gly
             20                  25                  30

Thr Lys Ala Gly Tyr Lys Leu Phe Ser Leu Ser Ser Val Glu Gln Leu
         35                  40                  45

Asp Gln Val His Gly Ser Asn Glu Ile Pro Asp Val Tyr Ile Val Glu
     50                  55                  60

Arg Leu Phe Ser Ser Ser Leu Val Val Val Val Ser His Thr Lys Pro
 65                  70                  75                  80

Arg Gln Met Asn Val Tyr His Phe Lys Lys Gly Thr Glu Ile Cys Asn
                 85                  90                  95

Tyr Ser Tyr Ser Ser Asn Ile Leu Ser Ile Arg Leu Asn Arg Gln Arg
            100                 105                 110

Leu Leu Val Cys Leu Glu Glu Ser Ile Tyr Ile His Asn Ile Lys Asp
        115                 120                 125

Met Lys Leu Leu Lys Thr Leu Leu Asp Ile Pro Ala Asn Pro Thr Gly
    130                 135                 140

Leu Cys Ala Leu Ser Ile Asn His Ser Asn Ser Tyr Leu Ala Tyr Pro
145                 150                 155                 160

Gly Ser Leu Thr Ser Gly Glu Ile Val Leu Tyr Asp Gly Asn Ser Leu
                165                 170                 175

Lys Thr Val Cys Thr Ile Ala Ala His Glu Gly Thr Leu Ala Ala Ile
            180                 185                 190

Thr Phe Asn Ala Ser Gly Ser Lys Leu Ala Ser Ala Ser Glu Lys Gly
        195                 200                 205

Thr Val Ile Arg Val Phe Ser Val Pro Asp Gly Gln Lys Leu Tyr Glu
    210                 215                 220

Phe Arg Arg Gly Met Lys Arg Tyr Val Thr Ile Ser Ser Leu Val Phe
225                 230                 235                 240

Ser Met Asp Ser Gln Phe Leu Cys Ala Ser Ser Asn Thr Glu Thr Val
                245                 250                 255

His Ile Phe Lys Leu Glu Gln Val Thr Asn Ser Arg Pro Glu Glu Pro
            260                 265                 270

Ser Thr Trp Ser Gly Tyr Met Gly Lys Met Phe Met Ala Ala Thr Asn
        275                 280                 285

Tyr Leu Pro Thr Gln Val Ser Asp Met Met His Gln Asp Arg Ala Phe
    290                 295                 300

Ala Thr Ala Arg Leu Asn Phe Ser Gly Gln Arg Asn Ile Cys Thr Leu
305                 310                 315                 320

Ser Thr Ile Gln Lys Leu Pro Arg Leu Leu Val Ala Ser Ser Ser Gly
                325                 330                 335

His Leu Tyr Met Tyr Asn Leu Asp Pro Gln Asp Gly Gly Glu Cys Val
            340                 345                 350

Leu Ile Lys Thr His Ser Leu Leu Gly Ser Gly Thr Thr Glu Glu Asn
        355                 360                 365

Lys Glu Asn Asp Leu Arg Pro Ser Leu Pro Gln Ser Tyr Ala Ala Thr
    370                 375                 380

Val Ala Arg Pro Ser Ala Ser Ser Ala Ser Thr Val Pro Gly Tyr Ser
385                 390                 395                 400

Glu Asp Gly Gly Ala Leu Arg Gly Glu Val Ile Pro Glu His Glu Phe
                405                 410                 415

Ala Thr Gly Pro Val Cys Leu Asp Asp Glu Asn Glu Phe Pro Pro Ile
            420                 425                 430

Ile Leu Cys Arg Gly Asn Gln Lys Gly Lys Thr Lys Gln Ser 
        435                 440                 445



<210> 1966
<211> 206
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1966
Met Ala Arg Gly Gly Trp Arg Arg Leu Arg Arg Leu Leu Ser Ala Gly
  1               5                  10                  15

Gln Leu Leu Phe Gln Gly Arg Ala Leu Leu Val Thr Asn Thr Leu Gly
             20                  25                  30

Cys Gly Ala Leu Met Ala Ala Gly Asp Gly Val Arg Gln Ser Trp Glu
         35                  40                  45

Ile Arg Ala Arg Pro Gly Gln Val Phe Asp Pro Arg Arg Ser Ala Ser
     50                  55                  60

Met Phe Ala Val Gly Cys Ser Xaa Gly Pro Phe Leu His Tyr Trp Tyr
 65                  70                  75                  80

Leu Ser Leu Asp Arg Leu Phe Pro Ala Ser Gly Leu Arg Gly Phe Pro
                 85                  90                  95

Asn Val Leu Lys Lys Val Leu Val Asp Gln Leu Val Ala Ser Pro Leu
            100                 105                 110

Leu Gly Val Trp Tyr Phe Leu Gly Leu Gly Cys Leu Glu Gly Gln Thr
        115                 120                 125

Val Gly Glu Ser Cys Gln Glu Leu Arg Glu Lys Phe Trp Glu Phe Tyr
    130                 135                 140

Lys Ala Asp Trp Cys Val Trp Pro Ala Ala His Xaa Val Asn Phe Leu
145                 150                 155                 160

Phe Val Pro Pro Gln Phe Arg Val Thr Tyr Ile Asn Gly Leu Thr Leu
                165                 170                 175

Gly Trp Asp Thr Tyr Leu Ser Tyr Leu Lys Tyr Arg Ser Pro Val Pro
            180                 185                 190

Leu Thr Pro Pro Gly Cys Val Ala Leu Asp Thr Arg Ala Asp 
        195                 200                 205



<210> 1967
<211> 185
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (171)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (176)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1967
Met Gly Gln Leu Lys Gly Phe Ser Ala His Trp Trp Asn Phe Arg His
  1               5                  10                  15

Phe Gln His His Ala Lys Pro Asn Ile Phe His Lys Asp Pro Asp Val
             20                  25                  30

Thr Val Ala Pro Val Phe Leu Leu Gly Glu Ser Ser Val Glu Tyr Gly
         35                  40                  45

Lys Lys Lys Arg Arg Tyr Leu Pro Tyr Asn Gln Gln His Leu Tyr Phe
     50                  55                  60

Phe Leu Ile Gly Pro Pro Leu Leu Thr Leu Val Asn Phe Glu Val Glu
 65                  70                  75                  80

Asn Leu Ala Tyr Met Leu Val Cys Met Gln Trp Ala Asp Leu Leu Trp
                 85                  90                  95

Ala Ala Ser Phe Tyr Ala Arg Phe Phe Leu Ser Tyr Leu Pro Phe Tyr
            100                 105                 110

Gly Val Pro Gly Val Leu Leu Phe Phe Val Ala Val Xaa Val Leu Glu
        115                 120                 125

Ser His Trp Phe Val Trp Ile Thr Gln Met Asn His Ile Pro Lys Glu
    130                 135                 140

Ile Gly His Glu Lys His Arg Asp Trp Val Ser Ser Gln Leu Ala Ala
145                 150                 155                 160

Thr Ala Thr Trp Ser Leu Thr Phe His Gln Xaa Val Gln Arg Asp Xaa
                165                 170                 175

Xaa Phe Pro Asp Arg Xaa Pro Pro Leu 
            180                 185



<210> 1968
<211> 179
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1968
Met Pro Glu Val Leu Leu Pro Pro Thr Arg Pro Pro Asp Leu Arg Ala
  1               5                  10                  15

Pro Gly Asp Leu Ser Val Ser Leu Cys Pro Pro Leu Gln Asp Leu Leu
             20                  25                  30

Trp Ala Ala Xaa Phe Tyr Ala Arg Phe Phe Leu Ser Tyr Leu Pro Phe
         35                  40                  45

Tyr Gly Val Pro Gly Val Leu Leu Xaa Phe Val Ala Val Arg Val Leu
     50                  55                  60

Glu Ser His Trp Phe Val Trp Ile Thr Gln Met Asn His Ile Pro Lys
 65                  70                  75                  80

Glu Ile Gly His Glu Lys His Arg Asp Trp Val Ser Ser Gln Leu Ala
                 85                  90                  95

Ala Thr Cys Asn Val Glu Pro Ser Leu Phe Thr Asn Trp Phe Ser Gly
            100                 105                 110

His Leu Asn Phe Gln Ile Glu His His Leu Phe Pro Arg Met Pro Arg
        115                 120                 125

His Asn Tyr Ser Arg Val Ala Pro Leu Val Lys Ser Leu Cys Ala Lys
    130                 135                 140

His Gly Leu Ser Tyr Glu Val Lys Pro Phe Leu Thr Ala Leu Val Asp
145                 150                 155                 160

Ile Val Arg Ser Leu Lys Lys Ser Gly Asp Ile Trp Leu Asp Ala Tyr
                165                 170                 175

Leu His Gln 




<210> 1969
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1969
Met Ser Glu Ile Leu Leu Ser Gln Val Thr Asn Met Arg Thr Glu Leu
  1               5                  10                  15

Ser Phe Asn Ile Gln Ala Leu Ala Val Cys Ala Asn Ile Cys Leu Ala
             20                  25                  30

Thr Lys Asp Arg Gln Asn Pro Ser Leu Val Trp Leu Phe Thr Gly Met
         35                  40                  45

Xaa Cys Ile Tyr Ser Leu Phe Phe Ala Trp Arg Ala Asn Leu Asp Ile
     50                  55                  60

Ser Lys Pro Leu Phe Met Gly Val Val Glu Arg Xaa Trp Met Xaa Ser
 65                  70                  75                  80

Asn Ala Val Val Ala Ala Ser Leu Ala Leu Val Xaa Leu Gln Leu Cys
                 85                  90                  95

Leu Arg Leu Asn Arg Val Leu Asn Ser Asn Gly Ala Xaa Val Ser Gly
            100                 105                 110

Asn Gly Leu Ser Ala Thr Leu Phe Gly Ser Leu Pro Lys Tyr Ile Leu
        115                 120                 125

Ile Thr Glu Lys Glu His Leu Phe Ala 
    130                 135



<210> 1970
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1970
Met Leu Phe Ser Leu Arg Glu Leu Val Gln Trp Leu Gly Phe Ala Thr
  1               5                  10                  15

Phe Glu Ile Phe Val His Leu Leu Ala Leu Leu Val Phe Ser Val Leu
             20                  25                  30

Leu Ala Leu Arg Val Asp Gly Leu Val Pro Gly Leu Ser Trp Trp Asn
         35                  40                  45

Val Phe Val Pro Phe Phe Ala Ala Asp Gly Leu Ser Thr Tyr Phe Thr
     50                  55                  60

Thr Ile Val Ser Val Arg Leu Phe Gln Asp Gly Glu Lys Arg Leu Ala
 65                  70                  75                  80

Val Leu Arg Leu Phe Trp Val Leu Thr Val Leu Ser Leu Lys Phe Val
                 85                  90                  95

Phe Glu Met Leu Leu Cys Gln Lys Leu Ala Xaa Gln Thr Arg Glu Leu
            100                 105                 110

Trp Phe Gly Leu Ile Thr Ser Pro Leu Phe Ile Leu Leu Gln Leu Leu
        115                 120                 125

Met Ile Arg Ala Cys Arg Val Asn 
    130                 135



<210> 1971
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1971
Met Gly Ser Ser Met Pro Thr Gly Ser Leu Pro Lys Pro Lys Arg Cys
  1               5                  10                  15

Gln Ala Val Ser Ser Val Leu Ala Gly Ser Arg Met Pro Pro Leu Leu
             20                  25                  30

Thr Glu Pro Ala Trp Ala Leu Pro Pro Thr Leu Trp Ser Leu Gly Leu
         35                  40                  45

Gly Ser Ala Tyr Pro Val Ala Gln Thr Gly Thr Pro Ala Ala Leu Gly
     50                  55                  60

Ala Val Ser Ser Lys Ile Ser Cys Pro Arg Gly Ala His Val Gly Pro
 65                  70                  75                  80

Leu Cys Pro Leu Ser Ser Ser Leu Phe Phe Leu Ile Leu Ala Lys Xaa
                 85                  90                  95

Gly Ser Leu Gly Gln Ala Gly Asn Asn Cys Gly Asp Ile Ser Asp Ser
            100                 105                 110






<210> 1972
<211> 471
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1972
Met Tyr Xaa Asn Cys Leu Arg Lys Phe Tyr Lys His Gln Asn Thr Glu
  1               5                  10                  15

Val Val Leu Tyr Leu Ala Arg Ala Leu Phe Lys Cys Gly Lys Leu Gln
             20                  25                  30

Glu Cys Lys Gln Thr Leu Leu Lys Ala Arg His Val Ala Pro Ser Asp
         35                  40                  45

Thr Val Leu Met Phe Asn Val Ala Leu Val Leu Gln Arg Leu Ala Thr
     50                  55                  60

Ser Val Leu Lys Asp Glu Lys Ser Asn Leu Lys Glu Val Leu Asn Ala
 65                  70                  75                  80

Val Lys Glu Leu Glu Leu Ala His Arg Tyr Phe Ser Tyr Leu Ser Lys
                 85                  90                  95

Val Gly Asp Lys Met Arg Phe Asp Leu Ala Leu Ala Ala Thr Glu Ala
            100                 105                 110

Arg Gln Cys Ser Asp Leu Leu Ser Gln Ala Gln Tyr His Val Ala Arg
        115                 120                 125

Ala Arg Lys Gln Asp Glu Glu Glu Arg Glu Leu Arg Ala Lys Gln Glu
    130                 135                 140

Gln Glu Lys Glu Leu Leu Arg Gln Lys Leu Leu Lys Glu Gln Glu Glu
145                 150                 155                 160

Lys Arg Leu Arg Glu Lys Glu Glu Gln Lys Lys Leu Leu Glu Gln Arg
                165                 170                 175

Ala Gln Tyr Val Glu Lys Thr Lys Asn Ile Leu Met Phe Thr Gly Glu
            180                 185                 190

Thr Glu Ala Thr Lys Glu Lys Lys Arg Gly Gly Gly Gly Gly Arg Arg
        195                 200                 205

Ser Lys Lys Gly Gly Glu Phe Asp Glu Phe Val Asn Asp Asp Thr Asp
    210                 215                 220

Asp Asp Leu Pro Ile Ser Lys Lys Lys Lys Arg Arg Lys Gly Ser Gly
225                 230                 235                 240

Ser Glu Gln Glu Gly Glu Asp Glu Glu Gly Gly Glu Arg Lys Lys Lys
                245                 250                 255

Lys Arg Arg Arg His Pro Lys Gly Glu Glu Gly Ser Asp Asp Asp Glu
            260                 265                 270

Thr Glu Asn Gly Pro Lys Pro Lys Lys Arg Arg Pro Pro Lys Ala Glu
        275                 280                 285

Lys Lys Lys Ala Pro Lys Pro Glu Arg Leu Pro Pro Ser Met Lys Gly
    290                 295                 300

Lys Ile Lys Ser Lys Ala Ile Ile Ser Ser Ser Asp Asp Ser Ser Asp
305                 310                 315                 320

Glu Asp Lys Leu Lys Ile Ala Asp Glu Gly His Pro Arg Asn Ser Asn
                325                 330                 335

Ser Asn Ser Asp Ser Asp Glu Asp Glu Gln Arg Lys Lys Cys Ala Ser
            340                 345                 350

Ser Glu Ser Asp Ser Asp Glu Asn Gln Asn Lys Ser Gly Ser Glu Ala
        355                 360                 365

Gly Ser Pro Arg Arg Pro Arg Arg Gln Arg Ser Asp Gln Asp Ser Asp
    370                 375                 380

Ser Asp Gln Pro Ser Arg Lys Arg Arg Pro Ser Gly Ser Glu Gln Ser
385                 390                 395                 400

Asp Asn Glu Ser Val Gln Ser Gly Arg Ser His Ser Gly Val Ser Glu
                405                 410                 415

Asn Asp Ser Arg Pro Ala Ser Pro Ser Ala Glu Ser Asp His Glu Ser
            420                 425                 430

Glu Arg Gly Ser Asp Asn Glu Gly Ser Gly Gln Gly Ser Gly Asn Glu
        435                 440                 445

Ser Glu Pro Glu Gly Ser Asn Asn Glu Ala Ser Asp Arg Gly Ser Glu
    450                 455                 460

His Gly Ser Asp Asp Ser Asp 
465                 470



<210> 1973
<211> 133
<212> PRT
<213> Homo sapiens

<400> 1973
Met Arg Met Ser Leu Ala Gln Arg Val Leu Leu Thr Trp Leu Phe Thr
  1               5                  10                  15

Leu Leu Phe Leu Ile Met Leu Val Leu Lys Leu Asp Glu Lys Ala Pro
             20                  25                  30

Trp Asn Trp Phe Leu Ile Phe Ile Pro Val Trp Ile Phe Asp Thr Ile
         35                  40                  45

Leu Leu Val Leu Leu Ile Val Lys Met Ala Gly Arg Cys Lys Ser Gly
     50                  55                  60

Phe Asp Pro Arg His Gly Ser His Asn Ile Lys Lys Lys Ala Trp Tyr
 65                  70                  75                  80

Leu Ile Ala Met Leu Leu Lys Leu Ala Phe Cys Leu Ala Leu Cys Ala
                 85                  90                  95

Lys Leu Glu Gln Phe Thr Thr Met Asn Leu Ser Tyr Val Phe Ile Pro
            100                 105                 110

Leu Trp Ala Leu Leu Ala Gly Ala Leu Thr Glu Leu Gly Tyr Asn Val
        115                 120                 125

Phe Phe Val Arg Asp 
    130



<210> 1974
<211> 173
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1974
Met Phe Val Ala Ser Glu Arg Lys Met Arg Ala His Gln Val Leu Thr
  1               5                  10                  15

Phe Leu Leu Leu Phe Val Ile Thr Ser Val Ala Ser Glu Asn Ala Ser
             20                  25                  30

Thr Ser Arg Gly Cys Gly Leu Asp Leu Leu Pro Gln Tyr Val Ser Leu
         35                  40                  45

Cys Asp Leu Asp Ala Ile Trp Gly Ile Val Val Glu Ala Val Ala Gly
     50                  55                  60

Ala Gly Ala Xaa Ile Thr Leu Leu Leu Met Leu Ile Leu Leu Val Arg
 65                  70                  75                  80

Leu Pro Phe Ile Lys Glu Lys Glu Lys Lys Ser Pro Val Gly Leu His
                 85                  90                  95

Phe Leu Phe Leu Leu Gly Thr Leu Gly Leu Phe Gly Leu Thr Phe Ala
            100                 105                 110

Phe Ile Ile Gln Glu Asp Glu Thr Ile Cys Ser Val Arg Arg Phe Leu
        115                 120                 125

Trp Gly Val Leu Phe Ala Leu Cys Phe Ser Cys Leu Leu Xaa Gln Ala
    130                 135                 140

Leu Ala Pro Cys Arg Lys Ala Trp Cys Arg His Trp Glu Xaa Gly Pro
145                 150                 155                 160

Ala Gly Leu Gln Ala Gly Xaa Ala Leu Ala Leu Val Pro 
                165                 170



<210> 1975
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1975
Met Leu Cys Leu Ser Ser Val Val Met Phe Leu Pro Gln Pro Gly Ala
  1               5                  10                  15

Ala Ser Xaa Pro Leu Phe Ile Trp Glu Ala Ser Cys His Ser Leu Gly
             20                  25                  30

Gln Asn Trp Ala Gln Gly Lys Gly Leu Ser Pro Glu Asp Gly Leu Glu
         35                  40                  45

Gly Leu Gly His Thr Arg Ala Trp Thr Phe Gly Ala Gly Glu Xaa Gly
     50                  55                  60

Leu Arg Leu Leu Asn Val Arg Gly Leu Leu Thr Arg Gly Pro Ser Arg
 65                  70                  75                  80

Gly Ser Leu Cys Pro Leu Leu Trp Ser Asp Gln Ala Leu His Leu Ser
                 85                  90                  95

Ala Gly Pro Leu Trp Gln Arg Ser Pro Val Leu Phe Leu Leu Phe Leu
            100                 105                 110

Phe Leu Thr Lys Ala Cys Ala Thr Ser Cys Pro 
        115                 120



<210> 1976
<211> 305
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1976
Met Ile Tyr Leu Thr Ser Gln Trp Phe Pro Gln Arg Asn Arg Ala Ser
  1               5                  10                  15

Ile Met Gly Leu Phe Tyr Met Gly Ala Pro Leu Ala Leu Thr Leu Gly
             20                  25                  30

Ser Pro Leu Ser Gly Ala Leu Leu Glu Met His Gly Phe Met Gly His
         35                  40                  45

Pro Gly Trp Phe Trp Met Phe Val Ile Glu Gly Leu Leu Ala Val Gly
     50                  55                  60

Ala Gly Val Phe Thr Phe Phe Trp Leu Asp Asp Thr Pro Glu Gln Ala
 65                  70                  75                  80

Arg Phe Leu Ser Lys Gln Glu Lys Thr Leu Leu Ile Asn Gln Leu Ala
                 85                  90                  95

Ser Glu Glu Gln Gln Lys Val Thr Ser Arg Leu Ser Asp Ala Leu Arg
            100                 105                 110

Asn Gly Arg Val Trp Gln Leu Ala Ile Ile Tyr Leu Thr Ile Gln Val
        115                 120                 125

Ala Val Tyr Gly Leu Xaa Phe Phe Leu Pro Thr Gln Val Ala Ala Leu
    130                 135                 140

Leu Gly Thr Lys Val Gly Phe Thr Ala Ser Val Val Thr Ala Ile Pro
145                 150                 155                 160

Trp Val Ala Ala Leu Phe Gly Thr Trp Leu Ile Pro Arg Tyr Ser Asp
                165                 170                 175

Lys Thr Gly Glu Arg Arg Asn Val Ala Ala Leu Thr Leu Leu Ala Ala
            180                 185                 190

Gly Ile Gly Ile Gly Leu Ser Gly Leu Leu Ser Pro Val Met Ala Ile
        195                 200                 205

Val Ala Leu Cys Val Ala Ala Ile Gly Phe Ile Ala Val Gln Pro Val
    210                 215                 220

Phe Trp Thr Met Pro Thr Gln Leu Leu Ser Gly Thr Ala Leu Ala Ala
225                 230                 235                 240

Gly Ile Gly Phe Val Asn Leu Phe Gly Ala Val Gly Gly Phe Ile Ala
                245                 250                 255

Pro Ile Leu Arg Val Lys Ala Glu Thr Leu Phe Ala Ser Asp Ala Ala
            260                 265                 270

Gly Leu Leu Thr Leu Ala Ala Val Ala Val Ile Gly Ser Leu Ile Ile
        275                 280                 285

Phe Thr Leu Arg Val Asn Arg Thr Val Ala Gln Thr Asp Val Ala His
    290                 295                 300

His 
305



<210> 1977
<211> 173
<212> PRT
<213> Homo sapiens

<400> 1977
Met Gly Thr Tyr Leu Gly Thr Phe Asp Asp Tyr Leu Glu Leu Phe Leu
  1               5                  10                  15

Gln Phe Gly Tyr Val Ser Leu Phe Ser Cys Val Tyr Pro Leu Ala Ala
             20                  25                  30

Ala Phe Ala Val Leu Asn Asn Phe Thr Glu Val Asn Ser Asp Ala Leu
         35                  40                  45

Lys Met Cys Arg Val Phe Lys Arg Pro Phe Ser Glu Pro Ser Ala Asn
     50                  55                  60

Ile Gly Val Trp Gln Leu Ala Phe Glu Thr Met Ser Val Ile Ser Val
 65                  70                  75                  80

Val Thr Asn Cys Ala Leu Ile Gly Met Ser Pro Gln Val Asn Ala Val
                 85                  90                  95

Phe Pro Glu Ser Lys Ala Asp Leu Ile Leu Ile Val Val Ala Val Glu
            100                 105                 110

His Ala Leu Leu Ala Leu Lys Phe Ile Leu Ala Phe Ala Ile Pro Asp
        115                 120                 125

Lys Pro Arg His Ile Gln Met Lys Leu Ala Arg Leu Glu Phe Glu Ser
    130                 135                 140

Leu Glu Ala Leu Lys Gln Gln Gln Met Lys Leu Val Thr Glu Asn Leu
145                 150                 155                 160

Lys Glu Glu Pro Met Glu Ser Gly Lys Glu Lys Ala Thr 
                165                 170



<210> 1978
<211> 101
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1978
Met Arg Lys Leu Gly Lys Lys Ser Ser Ser Val Leu Leu Leu Lys Val
  1               5                  10                  15

Trp Ser Met Asp Ser Ser Ile Ser Ile Thr Trp Asp Leu Leu Gly Arg
             20                  25                  30

Asn Val Glu Thr Gln Ala Ser Pro Gln Asn Leu Pro Phe Tyr Lys Thr
         35                  40                  45

Pro Arg Ser Cys Cys Glu Gly Arg Ala Ala Ser Ala Glu Glu Thr Glu
     50                  55                  60

Thr Ser Pro Arg Gly Val Thr Gly Xaa His Gln Gln Arg Thr Leu Val
 65                  70                  75                  80

Leu Ile Asp Ser Ala Val Leu Xaa Xaa Ile Asn Val Met Ala Val Leu
                 85                  90                  95

Pro Gly Pro Leu Xaa 
            100



<210> 1979
<211> 166
<212> PRT
<213> Homo sapiens

<400> 1979
Met Glu Tyr Leu His Gln Asn Gly His Ser Lys Tyr His Arg Arg Phe
  1               5                  10                  15

Leu Pro Val Val Gly Phe Gln Ala Ile Glu Glu Asp Gly Val Leu Ser
             20                  25                  30

Thr Val Arg Ile Gly Phe Ser His His Leu Leu Gln Lys Glu Thr Thr
         35                  40                  45

Val Val Gly Lys Glu Gln Glu Ala Pro Val Gly Val Leu Arg Ile Leu
     50                  55                  60

Leu Glu Glu Ile Thr Met Lys Val Val Glu Ala Arg Ala Ile Leu Thr
 65                  70                  75                  80

Glu Ala Leu Phe His His Tyr Asp Pro Leu Val Leu Gln Val Thr Ala
                 85                  90                  95

Gln Val Leu Gly Thr Val Leu Leu Glu Val Val Gly Asp Leu Asp Leu
            100                 105                 110

Pro Gly Leu Val Gln Ile Ala Ala Val Glu Ala Gln Glu Glu Ser Leu
        115                 120                 125

Leu Val Glu Ala Val Val Glu Val Val Met Tyr Ala Pro Leu His Asp
    130                 135                 140

Lys Asn Pro Phe Gly Asn Ile Leu Thr Val Tyr Glu His Phe Thr Arg
145                 150                 155                 160

Thr Ile Lys Ile Arg His 
                165



<210> 1980
<211> 418
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (203)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1980
Met Asp Met Asp Leu Leu Glu Ser Ser Asn Ile Ser Glu Gly Glu Ile
  1               5                  10                  15

Glu Arg Leu Ile Asn Leu Leu Glu Glu Val Phe His Leu Met Glu Thr
             20                  25                  30

Ala Pro His Thr Met Ile Gln Gln Pro Val Lys Ser Phe Pro Thr Met
         35                  40                  45

Ala Arg Ile Thr Gly Pro Pro Glu Arg Asp Asp Pro Tyr Pro Val Leu
     50                  55                  60

Phe Arg Tyr Leu His Ser His His Phe Leu Glu Leu Val Thr Leu Leu
 65                  70                  75                  80

Leu Ser Ile Pro Val Thr Ser Ala His Pro Gly Val Leu Gln Ala Thr
                 85                  90                  95

Lys Asp Val Leu Lys Phe Leu Ala Gln Ser Gln Lys Gly Leu Leu Phe
            100                 105                 110

Phe Met Ser Glu Tyr Glu Ala Thr Asn Leu Leu Ile Arg Ala Leu Cys
        115                 120                 125

His Phe Tyr Asp Gln Asp Glu Glu Glu Gly Leu Gln Ser Asp Gly Val
    130                 135                 140

Ile Asp Asp Ala Phe Ala Leu Trp Leu Gln Asp Ser Thr Gln Thr Leu
145                 150                 155                 160

Gln Cys Ile Thr Glu Leu Phe Ser His Phe Gln Arg Cys Thr Ala Ser
                165                 170                 175

Glu Glu Thr Asp His Ser Asp Leu Leu Gly Thr Leu His Asn Leu Tyr
            180                 185                 190

Leu Ile Thr Phe Asn Pro Val Gly Arg Ser Xaa Xaa Gly His Val Phe
        195                 200                 205

Ser Leu Glu Lys Asn Leu Gln Ser Leu Ile Thr Leu Met Glu Tyr Tyr
    210                 215                 220

Ser Lys Glu Ala Leu Gly Asp Ser Lys Ser Lys Xaa Ser Val Ala Tyr
225                 230                 235                 240

Asn Tyr Ala Cys Ile Leu Ile Leu Val Val Val Gln Ser Ser Ser Asp
                245                 250                 255

Val Gln Met Leu Glu Gln His Ala Ala Ser Leu Leu Lys Leu Cys Lys
            260                 265                 270

Ala Asp Glu Asn Asn Ala Lys Leu Gln Glu Leu Gly Lys Trp Leu Glu
        275                 280                 285

Pro Leu Lys Asn Leu Arg Phe Glu Ile Asn Cys Ile Pro Asn Leu Ile
    290                 295                 300

Glu Tyr Val Lys Gln Asn Ile Asp Asn Leu Met Thr Pro Glu Gly Val
305                 310                 315                 320

Gly Leu Thr Thr Ala Leu Arg Val Leu Cys Asn Val Ala Cys Pro Pro
                325                 330                 335

Pro Pro Val Glu Gly Gln Gln Lys Asp Leu Lys Trp Asn Leu Ala Val
            340                 345                 350

Ile Gln Leu Phe Ser Ala Glu Gly Met Asp Thr Phe Ile Arg Val Leu
        355                 360                 365

Gln Lys Leu Asn Ser Ile Leu Thr Gln Pro Trp Arg Leu His Val Asn
    370                 375                 380

Met Gly Thr Thr Leu His Arg Val Thr Thr Ile Ser Met Ala Arg Cys
385                 390                 395                 400

Thr Leu Thr Leu Leu Lys Thr Met Leu Thr Glu Leu Leu Arg Gly Gly
                405                 410                 415

Ser Phe 




<210> 1981
<211> 368
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (350)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (354)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1981
Met Arg Arg Val Val Arg Gln Ser Lys Phe Arg His Val Phe Gly Gln
  1               5                  10                  15

Ala Val Lys Asn Asp Gln Cys Tyr Asp Asp Ile Arg Val Ser Arg Val
             20                  25                  30

Thr Trp Asp Ser Ser Phe Cys Ala Val Asn Pro Arg Phe Val Ala Ile
         35                  40                  45

Ile Ile Glu Ala Ser Gly Gly Gly Ala Phe Leu Val Leu Pro Leu His
     50                  55                  60

Lys Thr Gly Arg Ile Asp Lys Ser Tyr Pro Thr Val Cys Gly His Thr
 65                  70                  75                  80

Gly Pro Val Leu Asp Ile Asp Trp Cys Pro His Asn Asp Gln Val Ile
                 85                  90                  95

Ala Ser Gly Ser Glu Asp Cys Thr Val Met Val Trp Gln Ile Pro Glu
            100                 105                 110

Asn Gly Leu Thr Leu Ser Leu Thr Glu Pro Val Val Ile Leu Glu Gly
        115                 120                 125

His Ser Lys Arg Val Gly Ile Val Ala Trp His Pro Thr Ala Arg Asn
    130                 135                 140

Val Leu Leu Ser Ala Gly Cys Asp Asn Ala Ile Ile Ile Trp Asn Val
145                 150                 155                 160

Gly Thr Gly Glu Ala Leu Ile Asn Leu Asp Asp Met His Ser Asp Met
                165                 170                 175

Ile Tyr Asn Val Ser Trp Asn Arg Asn Gly Ser Leu Ile Cys Thr Ala
            180                 185                 190

Ser Lys Asp Lys Lys Val Arg Val Ile Asp Pro Arg Lys Gln Glu Ile
        195                 200                 205

Val Ala Glu Lys Glu Lys Ala His Glu Gly Ala Arg Pro Met Arg Ala
    210                 215                 220

Ile Phe Leu Ala Asp Gly Asn Val Phe Thr Thr Gly Phe Ser Arg Met
225                 230                 235                 240

Ser Glu Arg Gln Leu Ala Leu Trp Asn Pro Lys Asn Met Gln Glu Pro
                245                 250                 255

Ile Ala Leu His Glu Met Asp Thr Ser Asn Gly Val Leu Leu Pro Phe
            260                 265                 270

Tyr Asp Pro Asp Thr Ser Ile Ile Tyr Leu Cys Gly Lys Gly Asp Ser
        275                 280                 285

Ser Ile Arg Tyr Phe Glu Ile Thr Asp Glu Ser Pro Tyr Val His Tyr
    290                 295                 300

Leu Asn Thr Phe Ser Ser Lys Glu Pro Gln Arg Gly Met Gly Tyr Met
305                 310                 315                 320

Pro Lys Arg Gly Leu Asp Val Asn Lys Cys Glu Ile Ala Arg Phe Phe
                325                 330                 335

Lys Leu His Glu Arg Lys Cys Glu Pro Ile Leu Asn Phe Xaa Trp Asn
            340                 345                 350

Leu Xaa Val Phe Ser Pro Pro Pro Lys Arg Gly Gly Lys Lys Lys Gly
        355                 360                 365






<210> 1982
<211> 275
<212> PRT
<213> Homo sapiens

<400> 1982
Met Ile Asp Ala Val Val Thr Ser Arg Ser Glu Asp Asp Glu Thr Lys
  1               5                  10                  15

Glu Lys Gln Val Arg Asp Lys Arg Arg Lys Thr Leu Val Ile Ile Glu
             20                  25                  30

Lys Thr Tyr Ser Leu Leu Leu Asp Val Glu Asp Tyr Glu Arg Arg Tyr
         35                  40                  45

Leu Leu Ser Leu Glu Glu Glu Arg Pro Ala Leu Met Asp Asp Arg Lys
     50                  55                  60

His Lys Ile Cys Ser Met Tyr Asp Asn Leu Arg Gly Lys Leu Pro Gly
 65                  70                  75                  80

Gln Glu Arg Pro Ser Asp Asp His Phe Val Gln Ile Met Cys Ile Arg
                 85                  90                  95

Lys Gly Lys Arg Met Val Ala Arg Ile Leu Pro Phe Leu Ser Thr Glu
            100                 105                 110

Gln Ala Ala Asp Ile Leu Met Thr Thr Ala Arg Asn Leu Pro Phe Leu
        115                 120                 125

Ile Lys Lys Asp Ala Gln Asp Glu Val Leu Pro Cys Leu Leu Ser Pro
    130                 135                 140

Phe Ser Leu Leu Leu Tyr His Leu Pro Ser Val Ser Ile Thr Ser Leu
145                 150                 155                 160

Leu Arg Gln Leu Met Asn Leu Pro Gln Ser Ala Ala Thr Pro Ala Leu
                165                 170                 175

Ser Asn Pro His Leu Thr Ala Val Leu Gln Asn Lys Phe Gly Leu Ser
            180                 185                 190

Leu Leu Leu Ile Leu Leu Ser Arg Gly Glu Asp Leu Gln Ser Ser Asp
        195                 200                 205

Pro Ala Thr Glu Ser Thr Gln Asn Asn Gln Trp Thr Glu Val Met Phe
    210                 215                 220

Met Ala Thr Arg Glu Leu Leu Arg Ile Pro Gln Ala Ala Leu Ala Lys
225                 230                 235                 240

Pro Ile Ser Ile Pro Thr Asn Leu Val Ser Leu Phe Ser Arg Tyr Val
                245                 250                 255

Asp Arg Gln Lys Leu Asn Leu Leu Glu Thr Lys Leu Gln Leu Val Gln
            260                 265                 270

Gly Ile Arg 
        275



<210> 1983
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1983
Met Gly His Ser Thr Gly Leu Pro Gly Phe Pro Xaa Pro Val Trp Ala
  1               5                  10                  15

Asn Pro Ser Met Gly Glu Asp Lys Gln Val Pro Leu Glu Ala Gly Gly
             20                  25                  30

Pro Glu Ser His Leu Gln Gly Ser Leu Gly Gln Val Glu Met Arg Met
         35                  40                  45

Gly Asn Ser Ile Gly Ala Arg Ser Leu Ser Pro Pro Ala Val Asn Arg
     50                  55                  60

Leu Trp Pro Val Pro Gly His Gln Lys Arg Glu Glu Glu Pro Arg Arg
 65                  70                  75                  80

Leu Phe Met Tyr Leu Phe Ile Tyr Leu Leu Tyr Leu Leu Ile Lys Lys
                 85                  90                  95

Val Leu Ser Arg Arg Arg Gly Arg Glu Phe Arg Thr Gly Thr Cys Arg
            100                 105                 110

Arg 




<210> 1984
<211> 113
<212> PRT
<213> Homo sapiens

<400> 1984
Met Val Lys Lys Tyr Thr Thr Phe Ser Lys Asp Arg Ala Ala Gly Ser
  1               5                  10                  15

Val Phe Arg Thr His Thr Ser Tyr Ser Arg Thr Ser Pro Leu Ser Gln
             20                  25                  30

Pro Arg Pro Gln Arg Arg Ser Arg Gln Cys Ile Arg Lys Ser Ile Ser
         35                  40                  45

Ala Ala Cys Ser Ser Ala Val His Ser Thr Ala Leu Leu His Thr His
     50                  55                  60

Leu Cys Thr Leu Ile Gly Thr Pro Ser Trp Leu Phe Gly Gln Ala Gly
 65                  70                  75                  80

Ile Ala Leu Leu Leu Leu Val Ile Ile Ser Tyr Pro Phe Pro Ser Thr
                 85                  90                  95

Arg Asp Phe Ser Ile Thr Ala Val Pro Arg Val Ser Met Leu His Ser
            100                 105                 110

Gln 




<210> 1985
<211> 408
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (148)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (149)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1985
Met Arg Thr Asp Ser Gly Ala Arg Leu Glu Glu Gly His Leu Arg Pro
  1               5                  10                  15

Pro Arg Ala Leu Pro Pro Val Pro Ser Gln Asp Asp Ile Pro Leu Ser
             20                  25                  30

Arg Pro Lys Lys Lys Lys Pro Arg Thr Lys Asn Thr Pro Ala Ser Ala
         35                  40                  45

Ser Leu Glu Gly Leu Ala Gln Thr Ala Gly Arg Arg Pro Ser Glu Gly
     50                  55                  60

Asn Glu Pro Ser Thr Lys Glu Leu Lys Glu His Pro Glu Ala Pro Val
 65                  70                  75                  80

Gln Arg Arg Gln Lys Lys Thr Arg Leu Pro Leu Glu Leu Glu Thr Ser
                 85                  90                  95

Ser Thr Gln Lys Lys Ser Ser Ser Ser Ser Leu Leu Arg Asn Glu Asn
            100                 105                 110

Gly Ile Asp Ala Glu Pro Ala Glu Glu Ala Val Ile Gln Lys Pro Arg
        115                 120                 125

Arg Lys Thr Lys Lys Thr Gln Pro Ala Glu Leu Gln Xaa Ala Asn Glu
    130                 135                 140

Leu Gly Val Xaa Xaa Glu Asp Ile Xaa Thr Asp Glu Gln Thr Thr Val
145                 150                 155                 160

Glu Gln Gln Ser Val Phe Thr Ala Pro Thr Gly Ile Ser Gln Pro Val
                165                 170                 175

Gly Lys Val Phe Val Glu Lys Ser Arg Arg Phe Gln Ala Ala Asp Arg
            180                 185                 190

Ser Glu Leu Ile Lys Thr Thr Glu Asn Ile Asp Val Ser Met Asp Val
        195                 200                 205

Lys Pro Ser Trp Thr Thr Arg Asp Val Ala Leu Thr Val His Arg Ala
    210                 215                 220

Phe Arg Met Ile Gly Leu Phe Ser His Gly Phe Leu Ala Gly Cys Ala
225                 230                 235                 240

Val Trp Asn Ile Val Val Ile Tyr Val Leu Ala Gly Asp Gln Leu Ser
                245                 250                 255

Asn Leu Ser Asn Leu Leu Gln Gln Tyr Lys Thr Leu Ala Tyr Pro Phe
            260                 265                 270

Gln Ser Leu Leu Tyr Leu Leu Leu Ala Leu Ser Thr Ile Ser Ala Phe
        275                 280                 285

Asp Arg Ile Asp Phe Ala Lys Ile Ser Val Ala Ile Arg Asn Phe Leu
    290                 295                 300

Ala Leu Asp Pro Thr Ala Leu Ala Ser Phe Leu Tyr Phe Thr Ala Leu
305                 310                 315                 320

Ile Leu Ser Leu Ser Gln Gln Met Thr Ser Asp Arg Ile His Leu Tyr
                325                 330                 335

Thr Pro Ser Ser Val Asn Gly Ser Leu Trp Glu Ala Gly Ile Glu Glu
            340                 345                 350

Gln Ile Leu Gln Pro Trp Ile Val Val Asn Leu Val Val Ala Leu Leu
        355                 360                 365

Val Gly Leu Ser Trp Leu Phe Leu Ser Tyr Arg Pro Gly Met Asp Leu
    370                 375                 380

Ser Glu Glu Leu Met Phe Ser Ser Glu Val Glu Glu Tyr Pro Asp Lys
385                 390                 395                 400

Glu Lys Glu Ile Lys Ala Ser Ser 
                405



<210> 1986
<211> 339
<212> PRT
<213> Homo sapiens

<400> 1986
Met Asn Trp Glu Leu Leu Leu Trp Leu Leu Val Leu Cys Ala Leu Leu
  1               5                  10                  15

Leu Leu Leu Val Gln Leu Leu Arg Phe Leu Arg Ala Asp Gly Asp Leu
             20                  25                  30

Thr Leu Leu Trp Ala Glu Trp Gln Gly Arg Arg Pro Glu Trp Glu Leu
         35                  40                  45

Thr Asp Met Val Val Trp Val Thr Gly Ala Ser Ser Gly Ile Gly Glu
     50                  55                  60

Glu Leu Ala Tyr Gln Leu Ser Lys Leu Gly Val Ser Leu Val Leu Ser
 65                  70                  75                  80

Ala Arg Arg Val His Glu Leu Glu Arg Val Lys Arg Arg Cys Leu Glu
                 85                  90                  95

Asn Gly Asn Leu Lys Glu Lys Asp Ile Leu Val Leu Pro Leu Asp Leu
            100                 105                 110

Thr Asp Thr Gly Ser His Glu Ala Ala Thr Lys Ala Val Leu Gln Glu
        115                 120                 125

Phe Gly Arg Ile Asp Ile Leu Val Asn Asn Gly Gly Met Ser Gln Arg
    130                 135                 140

Ser Leu Cys Met Asp Thr Ser Leu Asp Val Tyr Arg Lys Leu Ile Glu
145                 150                 155                 160

Leu Asn Tyr Leu Gly Thr Val Ser Leu Thr Lys Cys Val Leu Pro His
                165                 170                 175

Met Ile Glu Arg Lys Gln Gly Lys Ile Val Thr Val Asn Ser Ile Leu
            180                 185                 190

Gly Ile Ile Ser Val Pro Leu Ser Ile Gly Tyr Cys Ala Ser Lys His
        195                 200                 205

Ala Leu Arg Gly Phe Phe Asn Gly Leu Arg Thr Glu Leu Ala Thr Tyr
    210                 215                 220

Pro Gly Ile Ile Val Ser Asn Ile Cys Pro Gly Pro Val Gln Ser Asn
225                 230                 235                 240

Ile Val Glu Asn Ser Leu Ala Gly Glu Val Thr Lys Thr Ile Gly Asn
                245                 250                 255

Asn Gly Asp Gln Ser His Lys Met Thr Thr Ser Arg Cys Val Arg Leu
            260                 265                 270

Met Leu Ile Ser Met Ala Asn Asp Leu Lys Glu Val Trp Ile Ser Glu
        275                 280                 285

Gln Pro Phe Leu Leu Val Thr Tyr Leu Trp Gln Tyr Met Pro Thr Trp
    290                 295                 300

Ala Trp Trp Ile Thr Asn Lys Met Gly Lys Lys Arg Ile Glu Asn Phe
305                 310                 315                 320

Lys Ser Gly Val Asp Ala Asp Ser Ser Tyr Phe Lys Ile Phe Lys Thr
                325                 330                 335

Lys His Asp 




<210> 1987
<211> 122
<212> PRT
<213> Homo sapiens

<400> 1987
Met Phe Gly Ala Met Ser Leu Tyr Gly Tyr Thr Thr Lys Arg Asp Leu
  1               5                  10                  15

Ser Gly Phe Gly Asn Met Leu Phe Met Ala Leu Ile Gly Ile Val Leu
             20                  25                  30

Ala Ser Leu Val Asn Phe Trp Leu Lys Ser Glu Ala Leu Met Trp Ala
         35                  40                  45

Val Thr Tyr Ile Gly Val Ile Val Phe Val Gly Leu Thr Ala Tyr Asp
     50                  55                  60

Thr Gln Lys Leu Lys Asn Met Gly Glu Gln Ile Asp Thr Arg Asp Thr
 65                  70                  75                  80

Ser Asn Leu Arg Lys Tyr Ser Ile Leu Gly Ala Leu Thr Leu Tyr Leu
                 85                  90                  95

Asp Phe Ile Asn Leu Phe Leu Met Leu Leu Arg Ile Phe Gly Asn Arg
            100                 105                 110

Arg Glu Ser Glu Glu Arg Gln Pro Gly Arg 
        115                 120



<210> 1988
<211> 281
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (218)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1988
Met Thr Pro Arg Ile His Leu Leu Gly Gly Pro Val Met Thr Pro Arg
  1               5                  10                  15

Ile Leu Leu Pro Ser Glu Gly Leu Val Met Thr Gln Thr His Leu Leu
             20                  25                  30

Pro Gly Gly Ser Val Met Thr Pro Gln Thr Leu His Pro Gln Gly Gly
         35                  40                  45

Pro Val Met Ile Leu Gln Ile Leu Leu Pro Gln Gly Gly Leu Ser Ile
     50                  55                  60

Ile Leu Gln Val His Leu Leu Gly Glu Ser Val Met Ile His Gln Ile
 65                  70                  75                  80

Pro Leu Leu Leu Gly Glu Pro Val Met Val Pro Gln Ile Ser Leu Pro
                 85                  90                  95

Pro Glu Gly Ser Ile Thr Thr Pro Leu Thr His Leu Gly Gly Leu Leu
            100                 105                 110

Ala Leu Gln Thr His Ser Asn Ser Glu Gly Pro Val Met Thr Pro Leu
        115                 120                 125

Ile Trp Leu Leu Met Ser Leu Ile Pro Cys Pro Glu Pro Lys Val Val
    130                 135                 140

Lys Pro Gln Lys Glu Pro Leu Ala Arg Leu Leu His Ile Gly Arg Ser
145                 150                 155                 160

Gln Glu Pro Pro Ile Cys His Ser Gln Arg Thr Ala Asn Met Ser Met
                165                 170                 175

Thr Leu Thr Ser Leu Leu His Glu Lys Ser Lys Gln Asn Pro Ile Leu
            180                 185                 190

Glu Thr Arg Ser Ser Leu Ile Pro Lys Val Thr Ala Arg Lys Gln Leu
        195                 200                 205

Ile Gln Thr Phe Leu Leu His Gly Ile Xaa Lys Val Gln Gly Thr Arg
    210                 215                 220

Ile Leu Ile Gln Ile Cys His Leu His Gly Ile Asp Leu Asp Thr Gly
225                 230                 235                 240

Ala Leu Ile Leu Thr Ser Leu His Gln Gly Gly Asp Arg Gly Pro Asn
                245                 250                 255

Leu Leu Ile Leu Thr Cys Pro Arg Leu Glu Gly Val Ser Leu Leu Glu
            260                 265                 270

Arg Ser Cys Thr His Val Phe Trp Gly 
        275                 280



<210> 1989
<211> 117
<212> PRT
<213> Homo sapiens

<400> 1989
Met Gly Lys Glu Trp Gly Trp Gln Glu Met Glu Asn Gly Gly Ala Ala
  1               5                  10                  15

Pro Ala Trp Gly Ala Gly Pro Pro Val His Pro Ala Pro Pro Pro Val
             20                  25                  30

Glu Lys Thr Leu Ser Trp Gly Cys Gly Phe Gly Leu His Ser Gly Phe
         35                  40                  45

Gly Gly Ser Gly Gly Gly Val Gly Leu Cys Arg Leu Leu Cys Leu Val
     50                  55                  60

Arg Leu Phe Cys Cys Ser Ser Ile Leu Tyr Gln Arg Gln Glu Arg Gly
 65                  70                  75                  80

Val Lys Ser Leu Phe Tyr Pro Pro Asn Lys Leu Ser His Ser Glu Ala
                 85                  90                  95

Glu Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
            100                 105                 110

Lys Lys Gly Gly Gly 
        115



<210> 1990
<211> 435
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (249)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (266)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1990
Met Pro Leu Phe Leu Leu Ser Leu Pro Thr Pro Pro Ser Ala Ser Gly
  1               5                  10                  15

His Glu Arg Arg Gln Arg Pro Glu Ala Lys Thr Ser Gly Ser Glu Lys
             20                  25                  30

Lys Tyr Leu Arg Ala Met Gln Ala Asn Arg Ser Gln Leu His Ser Pro
         35                  40                  45

Pro Gly Thr Gly Ser Ser Glu Asp Ala Ser Thr Pro Gln Cys Val His
     50                  55                  60

Thr Arg Leu Thr Gly Glu Gly Ser Cys Pro His Ser Gly Asp Val His
 65                  70                  75                  80

Ile Gln Ile Asn Ser Ile Pro Lys Glu Cys Ala Glu Asn Ala Ser Ser
                 85                  90                  95

Arg Asn Ile Arg Ser Gly Val His Ser Cys Ala His Gly Cys Val His
            100                 105                 110

Ser Arg Leu Arg Gly His Ser His Ser Glu Ala Arg Leu Thr Asp Asp
        115                 120                 125

Thr Ala Ala Glu Ser Gly Asp His Gly Ser Ser Ser Phe Ser Glu Phe
    130                 135                 140

Arg Tyr Leu Phe Lys Trp Leu Gln Lys Ser Leu Pro Tyr Ile Leu Ile
145                 150                 155                 160

Leu Ser Val Lys Leu Val Met Gln His Ile Thr Gly Ile Ser Leu Gly
                165                 170                 175

Ile Gly Leu Leu Thr Thr Phe Met Tyr Ala Asn Lys Ser Ile Val Asn
            180                 185                 190

Gln Val Phe Leu Arg Glu Arg Ser Ser Lys Ile Gln Cys Ala Trp Leu
        195                 200                 205

Leu Val Phe Leu Ala Gly Ser Ser Val Leu Leu Tyr Tyr Thr Phe His
    210                 215                 220

Ser Gln Ser Leu Tyr Tyr Ser Leu Ile Phe Leu Asn Pro Thr Leu Asp
225                 230                 235                 240

His Leu Ser Phe Trp Glu Val Phe Xaa Ile Val Gly Ile Thr Asp Phe
                245                 250                 255

Ile Leu Lys Phe Phe Phe Met Gly Leu Xaa Cys Leu Ile Leu Leu Val
            260                 265                 270

Pro Ser Phe Ile Met Pro Phe Lys Ser Lys Gly Tyr Trp Tyr Met Leu
        275                 280                 285

Leu Glu Glu Leu Cys Gln Tyr Tyr Arg Thr Phe Val Pro Ile Pro Val
    290                 295                 300

Trp Phe Arg Tyr Leu Ile Ser Tyr Gly Glu Phe Gly Asn Val Thr Arg
305                 310                 315                 320

Trp Ser Leu Gly Ile Leu Leu Ala Leu Leu Tyr Leu Ile Leu Lys Leu
                325                 330                 335

Leu Glu Phe Phe Gly His Leu Arg Thr Phe Arg Gln Val Leu Arg Ile
            340                 345                 350

Phe Phe Thr Gln Pro Ser Tyr Gly Val Ala Ala Ser Lys Arg Gln Cys
        355                 360                 365

Ser Asp Val Asp Asp Ile Cys Ser Ile Cys Gln Ala Glu Phe Gln Lys
    370                 375                 380

Pro Ile Leu Leu Ile Cys Gln His Ile Phe Cys Glu Glu Cys Met Thr
385                 390                 395                 400

Leu Trp Phe Asn Arg Glu Lys Thr Cys Pro Leu Cys Arg Thr Val Ile
                405                 410                 415

Ser Asp His Ile Asn Lys Trp Lys Asp Gly Ala Thr Ser Ser His Leu
            420                 425                 430

Gln Ile Tyr 
        435



<210> 1991
<211> 770
<212> PRT
<213> Homo sapiens

<400> 1991
Met Val Pro Gln Gly Ile Arg Pro Val Val Gln Leu Thr Ala Ile Glu
  1               5                  10                  15

Ile Leu Ala Trp Gly Leu Arg Asn Met Lys Asn Phe Gln Met Ala Ser
             20                  25                  30

Ile Thr Ser Pro Ser Leu Val Val Glu Cys Gly Gly Glu Arg Val Glu
         35                  40                  45

Ser Val Val Ile Lys Asn Leu Lys Lys Thr Pro Asn Phe Pro Ser Ser
     50                  55                  60

Val Leu Phe Met Lys Val Phe Leu Pro Lys Glu Glu Leu Tyr Met Pro
 65                  70                  75                  80

Pro Leu Val Ile Lys Val Ile Asp His Arg Gln Phe Gly Arg Lys Pro
                 85                  90                  95

Val Val Gly Gln Cys Thr Ile Glu Arg Leu Asp Arg Phe Arg Cys Asp
            100                 105                 110

Pro Tyr Ala Gly Lys Glu Asp Ile Val Pro Gln Leu Lys Ala Ser Leu
        115                 120                 125

Leu Ser Ala Pro Pro Cys Arg Asp Ile Val Ile Glu Met Glu Asp Thr
    130                 135                 140

Lys Pro Leu Leu Ala Ser Lys Leu Thr Glu Lys Glu Glu Glu Ile Val
145                 150                 155                 160

Asp Trp Trp Ser Lys Phe Tyr Ala Ser Ser Gly Glu His Glu Lys Cys
                165                 170                 175

Gly Gln Tyr Ile Gln Lys Gly Tyr Ser Lys Leu Lys Ile Tyr Asn Cys
            180                 185                 190

Glu Leu Glu Asn Val Ala Glu Phe Glu Gly Leu Thr Asp Phe Ser Asp
        195                 200                 205

Thr Phe Lys Leu Tyr Arg Gly Lys Ser Asp Glu Asn Glu Asp Pro Ser
    210                 215                 220

Val Val Gly Glu Phe Lys Gly Ser Phe Arg Ile Tyr Pro Leu Pro Asp
225                 230                 235                 240

Asp Pro Ser Val Pro Ala Pro Pro Arg Gln Phe Arg Glu Leu Pro Asp
                245                 250                 255

Ser Val Pro Gln Glu Cys Thr Val Arg Ile Tyr Ile Val Arg Gly Leu
            260                 265                 270

Glu Leu Gln Pro Gln Asp Asn Asn Gly Leu Cys Asp Pro Tyr Ile Lys
        275                 280                 285

Ile Thr Leu Gly Lys Lys Val Ile Glu Asp Arg Asp His Tyr Ile Pro
    290                 295                 300

Asn Thr Leu Asn Pro Val Phe Gly Arg Met Tyr Glu Leu Ser Cys Tyr
305                 310                 315                 320

Leu Pro Gln Glu Lys Asp Leu Lys Ile Ser Val Tyr Asp Tyr Asp Thr
                325                 330                 335

Phe Thr Arg Asp Glu Lys Val Gly Glu Thr Ile Ile Asp Leu Glu Asn
            340                 345                 350

Arg Phe Leu Ser Arg Phe Gly Ser His Cys Gly Ile Pro Glu Glu Tyr
        355                 360                 365

Cys Val Ser Gly Val Asn Thr Trp Arg Asp Gln Leu Arg Pro Thr Gln
    370                 375                 380

Leu Leu Gln Asn Val Ala Arg Phe Lys Gly Phe Pro Gln Pro Ile Leu
385                 390                 395                 400

Ser Glu Asp Gly Ser Arg Ile Arg Tyr Gly Gly Arg Asp Tyr Ser Leu
                405                 410                 415

Asp Glu Phe Glu Ala Asn Lys Ile Leu His Gln His Leu Gly Ala Pro
            420                 425                 430

Glu Glu Arg Leu Ala Leu His Ile Leu Arg Thr Gln Gly Leu Val Pro
        435                 440                 445

Glu His Val Glu Thr Arg Thr Leu His Ser Thr Phe Gln Pro Asn Ile
    450                 455                 460

Ser Gln Gly Lys Leu Gln Met Trp Val Asp Val Phe Pro Lys Ser Leu
465                 470                 475                 480

Gly Pro Pro Gly Pro Pro Phe Asn Ile Thr Pro Arg Lys Ala Lys Lys
                485                 490                 495

Tyr Tyr Leu Arg Val Ile Ile Trp Asn Thr Lys Asp Val Ile Leu Asp
            500                 505                 510

Glu Lys Ser Ile Thr Gly Glu Glu Met Ser Asp Ile Tyr Val Lys Gly
        515                 520                 525

Trp Ile Pro Gly Asn Glu Glu Asn Lys Gln Lys Thr Asp Val His Tyr
    530                 535                 540

Arg Ser Leu Asp Gly Glu Gly Asn Phe Asn Trp Arg Phe Val Phe Pro
545                 550                 555                 560

Phe Asp Tyr Leu Pro Ala Glu Gln Leu Cys Ile Val Ala Lys Lys Glu
                565                 570                 575

His Phe Trp Ser Ile Asp Gln Thr Glu Phe Arg Ile Pro Pro Arg Leu
            580                 585                 590

Ile Ile Gln Ile Trp Asp Asn Asp Lys Phe Ser Leu Asp Asp Tyr Leu
        595                 600                 605

Gly Phe Leu Glu Leu Asp Leu Arg His Thr Ile Ile Pro Ala Lys Ser
    610                 615                 620

Pro Glu Lys Cys Arg Leu Asp Met Ile Pro Asp Leu Lys Ala Met Asn
625                 630                 635                 640

Pro Leu Lys Ala Lys Thr Ala Ser Leu Phe Glu Gln Lys Ser Met Lys
                645                 650                 655

Gly Trp Trp Pro Cys Tyr Ala Glu Lys Asp Gly Ala Arg Val Met Ala
            660                 665                 670

Gly Lys Val Glu Met Thr Leu Glu Ile Leu Asn Glu Lys Glu Ala Asp
        675                 680                 685

Glu Arg Pro Ala Gly Lys Gly Arg Asp Glu Pro Asn Met Asn Pro Lys
    690                 695                 700

Leu Asp Leu Pro Asn Arg Pro Glu Thr Ser Phe Leu Trp Phe Thr Asn
705                 710                 715                 720

Pro Cys Lys Thr Met Lys Phe Ile Val Trp Arg Arg Phe Lys Trp Val
                725                 730                 735

Ile Ile Gly Leu Leu Phe Leu Leu Ile Leu Leu Leu Phe Val Ala Val
            740                 745                 750

Leu Leu Tyr Ser Leu Pro Asn Tyr Leu Ser Met Lys Ile Val Lys Pro
        755                 760                 765

Asn Val 
    770



<210> 1992
<211> 116
<212> PRT
<213> Homo sapiens

<400> 1992
Met Asp Gly Trp Asn Ser Met Ile Arg Tyr Tyr Lys Asn Asn Phe Ser
  1               5                  10                  15

Asp Gly Phe Arg Gln Asp Ser Ile Asp Leu Phe Leu Gly Asn Tyr Ser
             20                  25                  30

Val Asp Glu Leu Glu Ser His Ser Pro Leu Ser Val Pro Arg Asp Trp
         35                  40                  45

Lys Phe Leu Ala Leu Pro Ile Ile Met Val Val Ala Phe Ser Met Cys
     50                  55                  60

Ile Ile Cys Leu Leu Met Ala Gly Asp Thr Trp Thr Glu Thr Leu Ala
 65                  70                  75                  80

Tyr Val Leu Phe Trp Gly Val Ala Ser Ile Gly Thr Phe Phe Ile Ile
                 85                  90                  95

Leu Tyr Asn Gly Lys Asp Phe Val Asp Ala Pro Arg Leu Val Gln Lys
            100                 105                 110

Glu Lys Ile Asp 
        115



<210> 1993
<211> 102
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1993
Met Ile Pro Xaa Lys Asp Asn Arg Gly Thr Gln Asp Ala Leu Asn Pro
  1               5                  10                  15

Glu Asp Glu Val Asp Glu Phe Leu Ser Arg Ala Ile Asp Ala Arg Ser
             20                  25                  30

Ile Asp Gln Leu Arg Lys Asp His Val Arg Arg Phe Leu Leu Thr Phe
         35                  40                  45

Gln Arg Glu Asp Leu Glu Lys Lys Tyr Ser Arg Lys Val Asp Pro Arg
     50                  55                  60

Phe Gly Ala Tyr Val Ala Cys Ala Leu Leu Val Phe Cys Phe Ile Cys
 65                  70                  75                  80

Phe Ile Gln Leu Leu Ile Phe Pro His Ser Thr Leu Met Leu Gly Asp
                 85                  90                  95

Leu Xaa Xaa Gln Ser Ser 
            100



<210> 1994
<211> 226
<212> PRT
<213> Homo sapiens

<400> 1994
Met Lys Met Val Ala Pro Trp Thr Arg Phe Tyr Ser Asn Ser Cys Cys
  1               5                  10                  15

Leu Cys Cys His Val Arg Thr Gly Thr Ile Leu Leu Gly Val Trp Tyr
             20                  25                  30

Leu Ile Ile Asn Ala Val Val Leu Leu Ile Leu Leu Ser Ala Leu Ala
         35                  40                  45

Asp Pro Asp Gln Tyr Asn Phe Ser Ser Ser Glu Leu Gly Gly Asp Phe
     50                  55                  60

Glu Phe Met Asp Asp Ala Asn Met Cys Ile Ala Ile Ala Ile Ser Leu
 65                  70                  75                  80

Leu Met Ile Leu Ile Cys Ala Met Ala Thr Tyr Gly Ala Tyr Lys Gln
                 85                  90                  95

Arg Ala Ala Trp Ile Ile Pro Phe Phe Cys Tyr Gln Ile Phe Asp Phe
            100                 105                 110

Ala Leu Asn Met Leu Val Ala Ile Thr Val Leu Ile Tyr Pro Asn Ser
        115                 120                 125

Ile Gln Glu Tyr Ile Arg Gln Leu Pro Pro Asn Phe Pro Tyr Arg Asp
    130                 135                 140

Asp Val Met Ser Val Asn Pro Thr Cys Leu Val Leu Ile Ile Leu Leu
145                 150                 155                 160

Phe Ile Ser Ile Ile Leu Thr Phe Lys Gly Tyr Leu Ile Ser Cys Val
                165                 170                 175

Trp Asn Cys Tyr Arg Tyr Ile Asn Gly Arg Asn Ser Ser Asp Val Leu
            180                 185                 190

Val Tyr Val Thr Ser Asn Asp Thr Thr Val Leu Leu Pro Pro Tyr Asp
        195                 200                 205

Asp Ala Thr Val Asn Gly Ala Ala Lys Glu Pro Pro Pro Pro Tyr Val
    210                 215                 220

Ser Ala 
225



<210> 1995
<211> 162
<212> PRT
<213> Homo sapiens

<400> 1995
Met Leu Gln Thr Ser Asn Tyr Ser Leu Val Leu Ser Leu Gln Phe Leu
  1               5                  10                  15

Leu Leu Ser Tyr Asp Leu Phe Val Asn Ser Phe Ser Glu Leu Leu Gln
             20                  25                  30

Lys Thr Pro Val Ile Gln Leu Val Leu Phe Ile Ile Gln Asp Ile Ala
         35                  40                  45

Val Leu Phe Asn Ile Ile Ile Ile Phe Leu Met Phe Phe Asn Thr Phe
     50                  55                  60

Val Phe Gln Ala Gly Leu Val Asn Leu Leu Phe His Lys Phe Lys Gly
 65                  70                  75                  80

Thr Ile Ile Leu Thr Ala Val Tyr Phe Ala Leu Ser Ile Ser Leu His
                 85                  90                  95

Val Trp Val Met Asn Leu Arg Trp Lys Asn Ser Asn Ser Phe Ile Trp
            100                 105                 110

Thr Asp Gly Leu Gln Met Leu Phe Val Phe Gln Arg Leu Ala Ala Val
        115                 120                 125

Leu Tyr Cys Tyr Phe Tyr Lys Arg Thr Ala Val Arg Leu Gly Asp Pro
    130                 135                 140

His Phe Tyr Gln Asp Ser Leu Trp Leu Arg Lys Glu Phe Met Gln Val
145                 150                 155                 160

Arg Arg 




<210> 1996
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (169)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1996
Met Arg Glu Tyr Gln Arg Glu Leu Glu Glu Arg Glu Glu Lys Leu Lys
  1               5                  10                  15

Lys Arg Pro Leu Leu Phe Glu Arg Val Ala Gln Lys Asn Ala Arg Met
             20                  25                  30

Ala Ala Glu Lys His Tyr Ser Asn Thr Leu Lys Ala Leu Gly Ile Ser
         35                  40                  45

Asp Glu Phe Val Ser Lys Lys Gly Gln Ser Gly Lys Val Leu Glu Tyr
     50                  55                  60

Phe Asn Asn Gln Glu Thr Lys Ser Val Thr Glu Asp Lys Glu Ser Phe
 65                  70                  75                  80

Asn Glu Glu Glu Lys Ile Glu Glu Arg Glu Asn Gly Glu Glu Asn Tyr
                 85                  90                  95

Phe Ile Asp Thr Asn Ser Gln Asp Ser Tyr Xaa Glu Lys Xaa Glu Xaa
            100                 105                 110

Asn Glu Glu Ser Glu Glu Glu Lys Ser Xaa Glu Glu Ser His Xaa Ile
        115                 120                 125

Ile Lys Val Phe Ser Leu Cys Pro Cys Trp Trp Leu Gln Arg Gln Gly
    130                 135                 140

Val Ser Ser Arg Ile Trp Xaa Xaa Asn Ile Cys Gly Asp Leu Leu Ile
145                 150                 155                 160

Cys Ala Gly Leu Val Ile Lys Ala Xaa Xaa Pro Glu Lys Ala Glu Ser
                165                 170                 175






<210> 1997
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1997
Met Asn Arg Val Leu Cys Ala Pro Ala Ala Gly Ala Val Arg Ala Leu
  1               5                  10                  15

Arg Leu Ile Gly Trp Ala Ser Arg Ser Leu His Pro Leu Pro Gly Ser
             20                  25                  30

Arg Asp Arg Ala His Pro Ala Ala Glu Glu Glu Asp Asp Pro Asp Arg
         35                  40                  45

Pro Ile Glu Phe Ser Ser Ser Lys Ala Asn Pro His Arg Trp Ser Val
     50                  55                  60

Gly His Thr Met Gly Lys Gly His Gln Arg Pro Trp Trp Lys Val Leu
 65                  70                  75                  80

Pro Leu Ser Cys Phe Leu Val Ala Leu Ile Ile Trp Cys Xaa Leu Arg
                 85                  90                  95

Xaa Glu Ser Glu Ala Asp Gln Trp Leu Arg Gln Val Trp Gly Glu Val
            100                 105                 110

Pro Glu Pro Met Ile Val Leu Arg Ser Leu Arg Xaa Gln Leu Leu Gln
        115                 120                 125

Ser Glu Asn Leu Thr Gly Cys Pro Leu Gly Leu Xaa Glu Gly Ser Pro
    130                 135                 140

Thr Ala Ala 
145



<210> 1998
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1998
Met Arg Pro Phe Leu Phe Pro Ala Pro Pro Pro Gly Arg Ser Arg Xaa
  1               5                  10                  15

Ala Leu Gln Ser Leu Gly Ala Gly Gly Val Ala Val Gly Glu Gly Arg
             20                  25                  30

Pro His Pro Arg Trp Gly Leu Trp Pro Cys Val Ala Val Met Ser Met
         35                  40                  45

Ile Leu Val Phe Pro Asp Pro Trp Cys Cys Ser Pro Leu Ser Pro Ala
     50                  55                  60

Leu Phe Leu Val Cys Ile Tyr Val Ala Pro Val Met His Ile Tyr Thr
 65                  70                  75                  80

Gly Ile Lys Tyr Ile Ala Leu Tyr Asn Ile Ile Tyr Val Cys Gly Ile
                 85                  90                  95

Gln Gly Ile Thr Phe Met Arg Ala Lys Asp Lys Glu Phe Gly Gln Lys
            100                 105                 110

Met Gln Pro Ser Leu Cys Asp 
        115



<210> 1999
<211> 159
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 1999
Met Cys Ser Pro Ser Ala Leu Thr Pro Leu Pro Lys Gln Gly Ser Pro
  1               5                  10                  15

Arg Met Pro Ser Ser Gln Ala Leu Pro Pro Gly Pro Ser Thr Met Ala
             20                  25                  30

Leu Ala Gln Ser Ser Gly Trp Leu Ala Leu Gln Pro Ala Pro Cys Ser
         35                  40                  45

Ala Ser Pro Thr Arg Cys Gly Ala His Pro Tyr Pro Ala Glu Ser Ala
     50                  55                  60

Arg Cys Phe Ser Ala Ser Arg Glu Arg Ala Cys Cys Thr Thr Glu Ile
 65                  70                  75                  80

Val Thr Ala Ser Glu Ala Arg Xaa Ala Xaa Trp Val Trp Val Glu Ser
                 85                  90                  95

Glu Arg Ala Gly Leu Pro Gly Cys Thr Leu Thr Ala Pro Phe Leu Leu
            100                 105                 110

Leu Gly Val Leu Leu Glu Glu Arg Glu Phe Ser Ala Glu Arg Phe Ser
        115                 120                 125

Ala Leu Leu Met Cys Leu Pro Trp Arg Glu Pro Gly Pro Cys Cys Ser
    130                 135                 140

Gly Gly Ala Asp Cys Pro Val Leu Trp Ala Leu Gln Leu Cys Arg 
145                 150                 155



<210> 2000
<211> 154
<212> PRT
<213> Homo sapiens

<400> 2000
Met Ala Ser Ala Ser Ala Arg Gly Asn Gln Asp Lys Asp Ala His Phe
  1               5                  10                  15

Pro Pro Pro Ser Lys Gln Ser Leu Leu Phe Cys Pro Lys Ser Lys Leu
             20                  25                  30

His Ile His Arg Ala Glu Ile Ser Lys Ile Met Arg Glu Cys Gln Glu
         35                  40                  45

Glu Ser Phe Trp Lys Arg Ala Leu Pro Phe Ser Leu Val Ser Met Leu
     50                  55                  60

Val Thr Gln Gly Leu Val Tyr Gln Gly Tyr Leu Ala Ala Asn Ser Arg
 65                  70                  75                  80

Phe Gly Ser Leu Pro Lys Val Ala Leu Ala Gly Leu Leu Gly Phe Gly
                 85                  90                  95

Leu Gly Lys Val Ser Tyr Ile Gly Val Cys Gln Ser Lys Phe His Phe
            100                 105                 110

Phe Glu Asp Gln Leu Arg Gly Ala Gly Phe Gly Pro Gln His Asn Arg
        115                 120                 125

His Cys Leu Leu Thr Cys Glu Glu Cys Lys Ile Lys His Gly Leu Ser
    130                 135                 140

Glu Lys Gly Asp Ser Gln Pro Ser Ala Ser 
145                 150



<210> 2001
<211> 414
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2001
Met Ala Thr Leu Thr Thr Thr Gln Thr Ser Pro Ser Leu Leu Gly Gly
  1               5                  10                  15

Val Val Ile Ile Gly Gly Thr Ile Ile Gly Ala Gly Met Phe Ser Leu
             20                  25                  30

Pro Val Val Met Ser Gly Ala Trp Phe Phe Trp Ser Met Ala Ala Leu
         35                  40                  45

Ile Phe Thr Trp Phe Cys Met Leu His Ser Gly Leu Met Ile Leu Glu
     50                  55                  60

Ala Asn Leu Asn Tyr Arg Ile Gly Ser Ser Phe Asp Thr Ile Thr Lys
 65                  70                  75                  80

Asp Leu Leu Gly Lys Gly Trp Asn Val Val Asn Gly Ile Ser Ile Ala
                 85                  90                  95

Phe Val Leu Tyr Ile Leu Xaa Tyr Ala Tyr Ile Ser Ala Ser Gly Ser
            100                 105                 110

Ile Leu His His Thr Phe Ala Glu Met Ser Leu Asn Val Pro Ala Arg
        115                 120                 125

Ala Ala Gly Phe Gly Phe Ala Leu Leu Val Ala Phe Val Val Trp Leu
    130                 135                 140

Ser Thr Lys Ala Val Ser Arg Met Thr Ala Ile Val Leu Gly Ala Lys
145                 150                 155                 160

Val Ile Thr Phe Phe Leu Thr Phe Gly Ser Leu Leu Gly His Val Gln
                165                 170                 175

Pro Ala Thr Leu Phe Asn Val Ala Glu Ser Asn Ala Ser Tyr Ala Pro
            180                 185                 190

Tyr Leu Leu Met Thr Leu Pro Phe Cys Leu Ala Ser Phe Gly Tyr His
        195                 200                 205

Gly Asn Val Pro Ser Leu Met Lys Tyr Tyr Gly Lys Asp Pro Lys Thr
    210                 215                 220

Ile Val Lys Cys Leu Val Tyr Gly Thr Leu Met Ala Leu Ala Leu Tyr
225                 230                 235                 240

Thr Ile Trp Leu Leu Ala Thr Met Gly Asn Ile Pro Arg Pro Glu Phe
                245                 250                 255

Ile Gly Ile Ala Glu Lys Gly Gly Asn Ile Asp Val Leu Val Gln Ala
            260                 265                 270

Leu Ser Gly Val Leu Asn Ser Arg Ser Leu Asp Leu Leu Leu Val Val
        275                 280                 285

Phe Ser Asn Phe Ala Val Ala Ser Ser Phe Leu Gly Val Thr Leu Gly
    290                 295                 300

Leu Phe Asp Tyr Leu Ala Asp Leu Phe Gly Phe Asp Asp Ser Ala Val
305                 310                 315                 320

Gly Arg Leu Lys Thr Ala Leu Leu Thr Phe Ala Pro Pro Val Val Gly
                325                 330                 335

Gly Leu Leu Phe Pro Asn Gly Phe Leu Tyr Ala Ile Gly Tyr Ala Gly
            340                 345                 350

Leu Ala Ala Thr Ile Trp Ala Ala Ile Val Pro Ala Leu Leu Ala Arg
        355                 360                 365

Ala Ser Arg Lys Arg Phe Gly Ser Pro Lys Phe Arg Val Trp Gly Gly
    370                 375                 380

Lys Pro Met Ile Ala Leu Ile Leu Val Phe Gly Val Gly Asn Ala Leu
385                 390                 395                 400

Val His Ile Leu Ser Ser Phe Asn Leu Leu Pro Val Tyr Gln 
                405                 410



<210> 2002
<211> 613
<212> PRT
<213> Homo sapiens

<400> 2002
Met Phe Arg Cys Gly Gly Leu Ala Ala Gly Ala Leu Lys Gln Lys Leu
  1               5                  10                  15

Val Pro Leu Val Arg Thr Val Cys Val Arg Ser Pro Arg Gln Arg Asn
             20                  25                  30

Arg Leu Pro Gly Asn Leu Phe Gln Arg Trp His Val Pro Leu Glu Leu
         35                  40                  45

Gln Met Thr Arg Gln Met Ala Ser Ser Gly Ala Ser Gly Gly Lys Ile
     50                  55                  60

Asp Asn Ser Val Leu Val Leu Ile Val Gly Leu Ser Thr Val Gly Ala
 65                  70                  75                  80

Gly Ala Tyr Ala Tyr Lys Thr Met Lys Glu Asp Glu Lys Arg Tyr Asn
                 85                  90                  95

Glu Arg Ile Ser Gly Leu Gly Leu Thr Pro Glu Gln Lys Gln Lys Lys
            100                 105                 110

Ala Ala Leu Ser Ala Ser Glu Gly Glu Glu Val Pro Gln Asp Lys Ala
        115                 120                 125

Pro Ser His Val Pro Phe Leu Leu Ile Gly Gly Gly Thr Ala Ala Phe
    130                 135                 140

Ala Ala Ala Arg Ser Ile Arg Ala Arg Asp Pro Gly Ala Arg Val Leu
145                 150                 155                 160

Ile Val Ser Glu Asp Pro Glu Leu Pro Tyr Met Arg Pro Pro Leu Ser
                165                 170                 175

Lys Glu Leu Trp Phe Ser Asp Asp Pro Asn Val Thr Lys Thr Leu Arg
            180                 185                 190

Phe Lys Gln Trp Asn Gly Lys Glu Arg Ser Ile Tyr Phe Gln Pro Pro
        195                 200                 205

Ser Phe Tyr Val Ser Ala Gln Asp Leu Pro His Ile Glu Asn Gly Gly
    210                 215                 220

Val Ala Val Leu Thr Gly Lys Lys Val Val Gln Leu Asp Val Arg Asp
225                 230                 235                 240

Asn Met Val Lys Leu Asn Asp Gly Ser Gln Ile Thr Tyr Glu Lys Cys
                245                 250                 255

Leu Ile Ala Thr Gly Gly Thr Pro Arg Ser Leu Ser Ala Ile Asp Arg
            260                 265                 270

Ala Gly Ala Glu Val Lys Ser Arg Thr Thr Leu Phe Arg Lys Ile Gly
        275                 280                 285

Asp Phe Arg Ser Leu Glu Lys Ile Ser Arg Glu Val Lys Ser Ile Thr
    290                 295                 300

Ile Ile Gly Gly Gly Phe Leu Gly Ser Glu Leu Ala Cys Ala Leu Gly
305                 310                 315                 320

Arg Lys Ala Arg Ala Leu Gly Thr Glu Val Ile Gln Leu Phe Pro Glu
                325                 330                 335

Lys Gly Asn Met Gly Lys Ile Leu Pro Glu Tyr Leu Ser Asn Trp Thr
            340                 345                 350

Met Glu Lys Val Arg Arg Glu Gly Val Lys Val Met Pro Asn Ala Ile
        355                 360                 365

Val Gln Ser Val Gly Val Ser Ser Gly Lys Leu Leu Ile Lys Leu Lys
    370                 375                 380

Asp Gly Arg Lys Val Glu Thr Asp His Ile Val Ala Ala Val Gly Leu
385                 390                 395                 400

Glu Pro Asn Val Glu Leu Ala Lys Thr Gly Gly Leu Glu Ile Asp Ser
                405                 410                 415

Asp Phe Gly Gly Phe Arg Val Asn Ala Glu Leu Gln Ala Arg Ser Asn
            420                 425                 430

Ile Trp Val Ala Gly Asp Ala Ala Cys Phe Tyr Asp Ile Lys Leu Gly
        435                 440                 445

Arg Arg Arg Val Glu His His Asp His Ala Val Val Ser Gly Arg Leu
    450                 455                 460

Ala Gly Glu Asn Met Thr Gly Ala Ala Lys Pro Tyr Trp His Gln Ser
465                 470                 475                 480

Met Phe Trp Ser Asp Leu Gly Pro Asp Val Gly Tyr Glu Ala Ile Gly
                485                 490                 495

Leu Val Asp Ser Ser Leu Pro Thr Val Gly Val Phe Ala Lys Ala Thr
            500                 505                 510

Ala Gln Asp Asn Pro Lys Ser Ala Thr Glu Gln Ser Gly Thr Gly Ile
        515                 520                 525

Arg Ser Glu Ser Glu Thr Glu Ser Glu Ala Ser Glu Ile Thr Ile Pro
    530                 535                 540

Pro Ser Thr Pro Ala Val Pro Gln Ala Pro Val Gln Gly Glu Asp Tyr
545                 550                 555                 560

Gly Lys Gly Val Ile Phe Tyr Leu Arg Asp Lys Val Val Val Gly Ile
                565                 570                 575

Val Leu Trp Asn Ile Phe Asn Arg Met Pro Ile Ala Arg Lys Ile Ile
            580                 585                 590

Lys Asp Gly Glu Gln His Glu Asp Leu Asn Glu Val Ala Lys Leu Phe
        595                 600                 605

Asn Ile His Glu Asp 
    610



<210> 2003
<211> 294
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (291)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2003
Met Arg Arg Ala Lys Val Leu Asp Trp Gly Leu Gln Glu Gln Leu Trp
  1               5                  10                  15

Pro His Met Glu Ala Leu Arg Pro Arg Pro Ser Val Tyr Ile Pro Glu
             20                  25                  30

Phe Ile Ala Ala Asn Gln Ser Ala Arg Ala Asp Asn Leu Ile Pro Gly
         35                  40                  45

Ser Arg Ala Gln Gln Leu Glu Gln Ile Arg Arg Asp Ile Arg Asp Phe
     50                  55                  60

Arg Ser Ser Ala Gly Leu Asp Lys Val Ile Val Leu Trp Thr Ala Asn
 65                  70                  75                  80

Thr Glu Arg Phe Cys Glu Val Ile Pro Gly Leu Asn Asp Thr Ala Glu
                 85                  90                  95

Asn Leu Leu Arg Thr Ile Glu Leu Gly Leu Glu Val Ser Pro Ser Thr
            100                 105                 110

Leu Phe Ala Val Ala Ser Ile Leu Glu Gly Cys Ala Phe Leu Asn Gly
        115                 120                 125

Ser Pro Gln Asn Thr Leu Val Pro Gly Ala Leu Glu Leu Ala Trp Gln
    130                 135                 140

His Arg Val Phe Val Gly Gly Asp Asp Phe Lys Ser Gly Gln Thr Lys
145                 150                 155                 160

Val Lys Ser Val Leu Val Asp Phe Leu Ile Gly Ser Gly Leu Lys Thr
                165                 170                 175

Met Ser Ile Val Ser Tyr Asn His Leu Gly Asn Asn Asp Gly Glu Asn
            180                 185                 190

Leu Ser Ala Pro Leu Gln Phe Arg Ser Lys Glu Val Ser Lys Ser Asn
        195                 200                 205

Val Val Asp Asp Met Val Gln Ser Asn Pro Val Leu Tyr Thr Pro Gly
    210                 215                 220

Glu Glu Pro Asp His Cys Val Val Ile Lys Tyr Val Pro Tyr Val Gly
225                 230                 235                 240

Asp Ser Lys Arg Ala Leu Asp Glu Tyr Thr Ser Glu Leu Met Leu Gly
                245                 250                 255

Gly Thr Asn Thr Leu Val Leu His Asn Thr Cys Glu Asp Ser Leu Leu
            260                 265                 270

Ala Ala Pro Ile Met Leu Asp Leu Ala Leu Leu Thr Glu Leu Cys Gln
        275                 280                 285

Arg Val Xaa Phe Leu His 
    290



<210> 2004
<211> 139
<212> PRT
<213> Homo sapiens

<400> 2004
Met Asn Leu Asn Asn Thr Pro Thr Val Gly His Arg His Phe Glu Leu
  1               5                  10                  15

Val Thr Val Asp Val Asp Ser Phe Ala Thr Arg Arg Lys Met Pro Lys
             20                  25                  30

Cys Leu His His Gln Thr Thr Asp Ser Val Asp Phe Phe Ile Ala Lys
         35                  40                  45

Val Gly Ala Glu Arg Phe Val Glu Val Phe Asn Gly Ser Gln Cys Ala
     50                  55                  60

Tyr Gly Pro Gly Met Thr Thr Gln Leu Thr Glu Val Asp Ile Ile Phe
 65                  70                  75                  80

Phe Val Ile Leu Val Phe Asn Leu Thr Asn Asn Gln Phe Gln Asp Val
                 85                  90                  95

Phe Asn Gly His Gln Thr Gly Asn Pro Thr Glu Phe Val Asn Asn Asp
            100                 105                 110

Arg His Val Val Thr Leu Arg Ala Lys Leu Phe Gln His Pro Val Tyr
        115                 120                 125

Ala Leu Thr Phe Arg Asn Asp Asn Arg Leu Thr 
    130                 135



<210> 2005
<211> 103
<212> PRT
<213> Homo sapiens

<400> 2005
Met His Lys Trp Gln Leu Val Phe Leu Ser His Cys Leu Asn Phe Val
  1               5                  10                  15

Phe Ile Glu Ile Phe Tyr Thr Asp Trp Phe Ile Asp Gly Gln Phe Cys
             20                  25                  30

Thr Gln Thr Glu Gln Tyr Ser Thr Leu Pro Lys Met Ser Val Ala Leu
         35                  40                  45

Phe Lys His Cys Val Leu Thr Pro Val Leu Cys Asn Trp Val Val Val
     50                  55                  60

His Phe Ala Leu Pro Gly Val Thr Val Phe Asn Leu Ser Val Asn Lys
 65                  70                  75                  80

Val Ser Phe Asn Phe Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
                 85                  90                  95

Lys Lys Lys Lys Lys Lys Lys 
            100



<210> 2006
<211> 237
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2006
Met Gln Arg Gly Arg Arg Gly Pro Gln Trp Gly Gln Trp Gly Trp Gly
  1               5                  10                  15

Arg Gln Arg Gly Pro Gly Ser Thr Glu Pro Arg Glu Gly Glu Met Ser
             20                  25                  30

Pro Pro Gly Arg Thr Gly Ala His Val Cys Lys Glu Thr Val Val Cys
         35                  40                  45

Val Leu Ser Cys Ile Cys Val Cys Thr His Val Leu Gly Thr Arg Val
     50                  55                  60

Val Arg Ser Glu Arg Ala Pro Gly Cys Thr Gly Val Gly Cys Thr Gly
 65                  70                  75                  80

Thr Asp Ala Asp Gly Pro Gly Xaa Val Leu Trp Pro Pro Val Gly Trp
                 85                  90                  95

Met Arg Ala Val Cys Arg Glu Glu Pro Leu Gly Pro Phe Thr Arg Ser
            100                 105                 110

Ala Asp Thr His Gly Thr Asp Ala Leu Ser Phe Leu Leu Trp Gly Phe
        115                 120                 125

Pro Phe Ser Gly Leu Cys Ala Ala Pro Ala Leu Pro Arg Val Leu Leu
    130                 135                 140

Ala Ser Lys Glu Glu Leu Val Gly Gly Gly Cys Asp Leu Gln Thr Trp
145                 150                 155                 160

Val Ser Ala Leu Leu Trp Gly Trp Gly Leu Leu Ser Gln Arg Pro Ser
                165                 170                 175

Phe Pro Leu Thr Pro Pro Leu Pro Ala Ser Pro Gly Val Leu Ala Val
            180                 185                 190

Gly Ser Ser Glu Val Gly Glu Ala Cys Gly Val Ser Ala Leu His Leu
        195                 200                 205

Leu Leu Leu Leu Ser Pro Leu Pro Ala Ala Ser Ser Met Pro Lys Glu
    210                 215                 220

His Pro Trp Cys Ser Pro Gln Ala Arg Pro Gly Arg Gly 
225                 230                 235



<210> 2007
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2007
Met Ala Val Arg Leu Gln Gly Gln Gln Gly Ala Ala Met Thr Arg Ala
  1               5                  10                  15

Pro Xaa Ala Gly Tyr Ser Ala Gly Asp Phe Ser Ser Trp Asp Gly Trp
             20                  25                  30

Ala Cys Ser Ser Leu Glu Leu Arg Ala Leu Tyr Val Ile Ser Glu Gly
         35                  40                  45

Pro Ser Ala Ser Gly Val Val Pro Gln Glu His Arg Tyr Gln Leu His
     50                  55                  60

Phe Gln Asp Pro Ser Glu Lys Met Ile Met Phe Gln Ser Val Phe Cys
 65                  70                  75                  80

Leu Leu Phe Phe Ala Glu Leu Cys Cys Ile Ala Gly Ile Met Xaa Phe
                 85                  90                  95

Ser Lys Gly Lys Phe Pro Leu His 
            100



<210> 2008
<211> 344
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2008
Met Ala Ala Ile Tyr Gly Gly Val Glu Gly Gly Gly Thr Arg Ser Glu
  1               5                  10                  15

Val Leu Leu Val Ser Glu Asp Gly Lys Ile Leu Ala Glu Ala Asp Gly
             20                  25                  30

Leu Ser Thr Asn His Trp Leu Ile Gly Thr Asp Lys Cys Val Glu Arg
         35                  40                  45

Ile Asn Glu Met Val Asn Arg Ala Lys Arg Lys Ala Gly Val Asp Pro
     50                  55                  60

Leu Val Pro Leu Arg Xaa Leu Gly Leu Ser Leu Ser Gly Gly Asp Gln
 65                  70                  75                  80

Glu Asp Ala Gly Arg Ile Leu Ile Glu Glu Leu Arg Asp Arg Phe Pro
                 85                  90                  95

Tyr Leu Ser Glu Ser Tyr Leu Ile Thr Thr Asp Ala Ala Gly Ser Ile
            100                 105                 110

Ala Thr Ala Thr Pro Asp Gly Gly Val Val Leu Ile Ser Gly Thr Gly
        115                 120                 125

Ser Asn Cys Arg Leu Ile Asn Pro Asp Gly Ser Glu Ser Gly Cys Gly
    130                 135                 140

Gly Trp Gly His Met Met Gly Asp Glu Gly Ser Ala Tyr Trp Ile Ala
145                 150                 155                 160

His Gln Ala Val Lys Ile Val Phe Asp Ser Ile Asp Asn Leu Glu Ala
                165                 170                 175

Ala Pro His Asp Ile Gly Tyr Val Lys Gln Ala Met Phe His Tyr Phe
            180                 185                 190

Gln Val Pro Asp Arg Leu Gly Ile Leu Thr His Leu Tyr Arg Asp Phe
        195                 200                 205

Asp Lys Cys Arg Phe Ala Gly Phe Cys Arg Lys Ile Ala Glu Gly Ala
    210                 215                 220

Gln Gln Gly Asp Pro Leu Ser Arg Tyr Ile Phe Arg Lys Ala Gly Glu
225                 230                 235                 240

Met Leu Gly Arg His Ile Val Ala Val Leu Pro Glu Ile Asp Pro Val
                245                 250                 255

Leu Phe Gln Gly Lys Ile Gly Leu Pro Ile Leu Cys Val Gly Ser Val
            260                 265                 270

Trp Lys Ser Trp Glu Leu Leu Lys Glu Gly Phe Leu Leu Ala Leu Thr
        275                 280                 285

Gln Gly Arg Glu Ile Gln Ala Gln Asn Phe Phe Ser Ser Phe Thr Leu
    290                 295                 300

Met Lys Leu Arg His Ser Ser Ala Leu Gly Gly Ala Ser Leu Gly Ala
305                 310                 315                 320

Arg His Ile Gly His Leu Leu Pro Met Asp Tyr Ser Ala Asn Ala Ile
                325                 330                 335

Ala Phe Tyr Ser Tyr Thr Phe Ser 
            340



<210> 2009
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2009
Met Gln Tyr Lys Gly Arg Val Gly Pro Gly His Leu Ser His Asn Phe
  1               5                  10                  15

Ile Trp Ser Leu Gly Pro Ser Pro Phe His Lys Thr Arg Ile Tyr Phe
             20                  25                  30

Ser Tyr Pro Val Ile Cys Pro Asn Ile Pro Ala Phe Cys His Leu His
         35                  40                  45

Ser Leu Tyr Leu Pro Trp Xaa Thr Phe Thr Ser Thr Leu Gln Leu Tyr
     50                  55                  60

Ser Val Ile Tyr Ala Pro Cys Pro Ala Pro Pro Leu Ser Tyr Phe Ser
 65                  70                  75                  80

Ser His Val Leu Ile Pro Leu Pro His Met Leu Xaa Ser Phe Leu Ser
                 85                  90                  95

Thr His Val Ile Leu Leu Ser Leu Ile Xaa Asn Pro Gln Pro Pro Cys
            100                 105                 110

Tyr Pro Ala 
        115



<210> 2010
<211> 160
<212> PRT
<213> Homo sapiens

<400> 2010
Met Ile Leu Thr Gly Thr Ile Gln Leu Gly Leu Glu Ser Pro Arg Trp
  1               5                  10                  15

Cys His Ser His Val Trp His Leu Ser Trp Gly Asp Ser Ile Thr Trp
             20                  25                  30

Gly Leu Ala Gly Val Val Gly Leu Leu Phe Phe Ser Trp Ala Pro Ser
         35                  40                  45

Cys Ile Trp Ala Leu Val Leu Leu His Met Ser Ser Val Ser Met Cys
     50                  55                  60

Cys Leu Ile Tyr Gln Asp Leu Ser Pro Leu Asp Leu Ser Leu Gln Gln
 65                  70                  75                  80

Tyr Ser Val Asp Ser Ala His Gly Glu Phe Ser Ser Glu Gln Asn Gln
                 85                  90                  95

Glu Leu Gln Asp Thr Phe Arg Ala Gly Leu Arg Asn Leu Lys Phe Ser
            100                 105                 110

Phe Met Thr Asn Val Ser Ser Gly Gln Ser Lys Ser Gln Glu Gln Ser
        115                 120                 125

Arg Phe Lys Gly Lys Gly Pro Pro Leu Asp Arg Arg Ser Ser Thr His
    130                 135                 140

Val Arg Gly Lys Met Phe Gly Gly Leu Ala Cys Thr Leu Ile Leu Pro
145                 150                 155                 160






<210> 2011
<211> 196
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (183)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (194)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2011
Met Ala Asp Ala Ala Ser Gln Val Leu Leu Gly Ser Gly Leu Thr Ile
  1               5                  10                  15

Leu Ser Gln Pro Leu Met Tyr Val Lys Val Leu Ile Gln Val Gly Tyr
             20                  25                  30

Glu Pro Leu Pro Pro Thr Ile Gly Arg Asn Ile Phe Gly Arg Gln Val
         35                  40                  45

Cys Gln Leu Pro Gly Leu Phe Ser Tyr Ala Gln His Ile Ala Ser Ile
     50                  55                  60

Asp Gly Arg Arg Gly Leu Phe Thr Gly Leu Thr Pro Arg Leu Cys Ser
 65                  70                  75                  80

Gly Val Leu Gly Thr Val Val His Gly Lys Val Leu Gln His Tyr Gln
                 85                  90                  95

Glu Ser Asp Lys Gly Glu Glu Leu Gly Pro Gly Asn Val Gln Lys Glu
            100                 105                 110

Val Ser Ser Ser Phe Asp His Val Ile Lys Glu Thr Thr Arg Glu Met
        115                 120                 125

Ile Ala Arg Ser Ala Ala Thr Leu Ile Thr His Pro Phe His Val Ile
    130                 135                 140

Thr Leu Arg Ser Met Val Gln Phe Ile Gly Arg Glu Ser Lys Tyr Cys
145                 150                 155                 160

Gly Leu Cys Asp Ser Ile Ile Thr Ile Tyr Arg Glu Glu Gly Ile Leu
                165                 170                 175

Xaa Phe Phe Ala Gly Leu Xaa Pro Arg Leu Leu Gly Xaa Ile Leu Ser
            180                 185                 190

Leu Xaa Xaa Gly 
        195



<210> 2012
<211> 154
<212> PRT
<213> Homo sapiens

<400> 2012
Met Ala Phe Leu Gly Val Gln Ala Gly Lys Ile Leu Leu Tyr Tyr Lys
  1               5                  10                  15

Ala Arg Thr Lys Asp Ile Leu Ile Arg Phe Thr Ala Trp Cys Cys Ile
             20                  25                  30

Leu Gly Leu Ile Ser Val Ala Leu Thr Lys Val Ser Glu Asn Glu Gly
         35                  40                  45

Phe Ile Pro Val Asn Lys Asn Leu Trp Ser Leu Ser Tyr Val Thr Thr
     50                  55                  60

Leu Ser Ser Phe Ala Phe Phe Ile Leu Leu Val Leu Tyr Pro Val Val
 65                  70                  75                  80

Asp Val Lys Gly Leu Trp Thr Gly Thr Pro Phe Phe Tyr Pro Gly Met
                 85                  90                  95

Asn Ser Ile Leu Val Tyr Val Gly His Glu Val Phe Glu Asn Tyr Phe
            100                 105                 110

Pro Phe Gln Trp Lys Leu Lys Asp Asn Gln Ser His Lys Glu His Leu
        115                 120                 125

Thr Gln Asn Ile Val Ala Thr Ala Leu Trp Val Leu Ile Ala Tyr Ile
    130                 135                 140

Leu Tyr Arg Lys Lys Ile Phe Trp Lys Ile 
145                 150



<210> 2013
<211> 101
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2013
Met Ala Glu Ser Val Glu Arg Leu Gln Gln Arg Val Gln Glu Leu Glu
  1               5                  10                  15

Arg Glu Leu Ala Gln Glu Arg Ser Leu Gln Val Pro Arg Ser Gly Asp
             20                  25                  30

Gly Xaa Gly Gly Arg Val Arg Ile Glu Lys Met Ser Ser Glu Val Val
         35                  40                  45

Asp Ser Asn Pro Tyr Ser Arg Leu Met Ala Leu Lys Arg Met Gly Ile
     50                  55                  60

Val Ser Asp Tyr Glu Lys Ile Arg Thr Phe Ala Val Ala Ile Val Gly
 65                  70                  75                  80

Val Gly Gly Val Gly Ser Val Thr Ala Glu Met Leu Thr Arg Cys Gly
                 85                  90                  95

Ile Val Ala Thr Leu 
            100



<210> 2014
<211> 134
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2014
Met His Leu Leu Ala Gly Leu Ala Met Thr Arg His Ala Val Cys Pro
  1               5                  10                  15

Asn Pro Asp Asp Gly Arg Cys Gln Pro Arg Pro Cys Thr Leu Pro Leu
             20                  25                  30

Pro Leu Cys Leu Thr Leu Ala Gly Gln Leu Arg Gly Ala Met Gln Gly
         35                  40                  45

Pro Leu Pro Gly Gln Asp Leu Cys Arg Ala Gln Pro Gln Leu Ala Gly
     50                  55                  60

Val Phe Met Ala Trp Ser Pro Leu Pro Ala Ala Asp Ser Asp Val Ser
 65                  70                  75                  80

Trp His Gln Gly His Cys Ala Cys Gly Phe Arg Phe Leu Pro Cys Pro
                 85                  90                  95

Val Ala Gly Val Val Gly Xaa Leu Phe Ala Ala Trp Gln Asn Ser Ala
            100                 105                 110

Ala Leu Arg Lys Trp Met Ser Ala Tyr Cys Val Trp Gly Xaa Asp Gly
        115                 120                 125

Tyr Val Leu Ser Xaa Thr 
    130



<210> 2015
<211> 375
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (273)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2015
Met Val Ala Val Phe Leu Thr Phe Leu Met Leu Phe Arg Gly Arg Val
  1               5                  10                  15

Thr Leu Ala Trp Ala Leu Gly Tyr Leu Gly Leu Tyr Val Phe Tyr Val
             20                  25                  30

Val Thr Val Ile Leu Cys Thr Trp Ile Tyr Gln Arg Gln Arg Arg Gly
         35                  40                  45

Ser Leu Phe Cys Pro Met Pro Val Thr Pro Glu Ile Leu Ser Asp Ser
     50                  55                  60

Glu Glu Asp Arg Val Ser Ser Asn Thr Asn Ser Tyr Asp Tyr Gly Asp
 65                  70                  75                  80

Glu Tyr Arg Pro Leu Phe Phe Tyr Gln Glu Thr Thr Ala Gln Ile Leu
                 85                  90                  95

Val Arg Ala Leu Asn Pro Leu Asp Tyr Met Lys Trp Arg Arg Lys Ser
            100                 105                 110

Ala Tyr Trp Lys Ala Leu Lys Val Phe Lys Leu Pro Val Glu Phe Leu
        115                 120                 125

Leu Leu Leu Thr Val Pro Val Val Asp Pro Asp Lys Asp Asp Gln Asn
    130                 135                 140

Trp Lys Arg Pro Leu Asn Cys Leu His Leu Val Ile Ser Pro Leu Val
145                 150                 155                 160

Val Val Leu Thr Leu Gln Ser Gly Thr Tyr Gly Val Tyr Glu Ile Gly
                165                 170                 175

Gly Leu Val Pro Val Trp Val Val Val Val Ile Ala Gly Thr Ala Leu
            180                 185                 190

Ala Ser Val Thr Phe Phe Ala Thr Ser Asp Ser Gln Pro Pro Arg Leu
        195                 200                 205

His Trp Leu Phe Ala Phe Leu Gly Phe Leu Thr Ser Ala Leu Trp Ile
    210                 215                 220

Asn Ala Ala Ala Thr Glu Val Val Asn Ile Leu Arg Ser Leu Gly Val
225                 230                 235                 240

Val Phe Arg Leu Ser Asn Thr Val Leu Gly Leu Thr Leu Leu Ala Trp
                245                 250                 255

Gly Asn Ser Ile Gly Asp Ala Phe Ser Asp Phe Thr Leu Ala Arg Gln
            260                 265                 270

Xaa Tyr Pro Arg Met Ala Phe Ser Ala Cys Phe Gly Gly Ile Ile Phe
        275                 280                 285

Asn Ile Leu Val Gly Val Gly Leu Gly Cys Leu Leu Gln Ile Ser Arg
    290                 295                 300

Ser His Thr Glu Val Lys Leu Glu Pro Asp Gly Leu Leu Val Trp Val
305                 310                 315                 320

Leu Ala Gly Ala Leu Gly Leu Ser Leu Val Phe Ser Leu Val Ser Val
                325                 330                 335

Pro Leu Gln Cys Phe Gln Leu Ser Arg Val Tyr Gly Phe Cys Leu Leu
            340                 345                 350

Leu Phe Tyr Leu Asn Phe Leu Val Val Ala Leu Leu Thr Glu Phe Gly
        355                 360                 365

Val Ile His Leu Lys Ser Met 
    370                 375



<210> 2016
<211> 473
<212> PRT
<213> Homo sapiens

<400> 2016
Met Ala Ser Cys Val Gly Ser Arg Thr Leu Ser Lys Asp Asp Val Asn
  1               5                  10                  15

Tyr Lys Met His Phe Arg Met Ile Asn Glu Gln Gln Val Glu Asp Ile
             20                  25                  30

Thr Ile Asp Phe Phe Tyr Arg Pro His Thr Ile Thr Leu Leu Ser Phe
         35                  40                  45

Thr Ile Val Ser Leu Met Tyr Phe Ala Phe Thr Arg Asp Asp Ser Val
     50                  55                  60

Pro Glu Asp Asn Ile Trp Arg Gly Ile Leu Ser Val Ile Phe Phe Phe
 65                  70                  75                  80

Leu Ile Ile Ser Val Leu Ala Phe Pro Asn Gly Pro Phe Thr Arg Pro
                 85                  90                  95

His Pro Ala Leu Trp Arg Met Val Phe Gly Leu Ser Val Leu Tyr Phe
            100                 105                 110

Leu Phe Leu Val Phe Leu Leu Phe Leu Asn Phe Glu Gln Val Lys Ser
        115                 120                 125

Leu Met Tyr Trp Leu Asp Pro Asn Leu Arg Tyr Ala Thr Arg Glu Ala
    130                 135                 140

Asp Val Met Glu Tyr Ala Val Asn Cys His Val Ile Thr Trp Glu Arg
145                 150                 155                 160

Ile Ile Ser His Phe Asp Ile Phe Ala Phe Gly His Phe Trp Gly Trp
                165                 170                 175

Ala Met Lys Ala Leu Leu Ile Arg Ser Tyr Gly Leu Cys Trp Thr Ile
            180                 185                 190

Ser Ile Thr Trp Glu Leu Thr Glu Leu Phe Phe Met His Leu Leu Pro
        195                 200                 205

Asn Phe Ala Glu Cys Trp Trp Asp Gln Val Ile Leu Asp Ile Leu Leu
    210                 215                 220

Cys Asn Gly Gly Gly Ile Trp Leu Gly Met Val Val Cys Arg Phe Leu
225                 230                 235                 240

Glu Met Arg Thr Tyr His Trp Ala Ser Phe Lys Asp Ile His Thr Thr
                245                 250                 255

Thr Gly Lys Ile Lys Arg Ala Val Leu Gln Phe Thr Pro Ala Ser Trp
            260                 265                 270

Thr Tyr Val Arg Trp Phe Asp Pro Lys Ser Ser Phe Gln Arg Val Ala
        275                 280                 285

Gly Val Tyr Leu Phe Met Ile Ile Trp Gln Leu Thr Glu Leu Asn Thr
    290                 295                 300

Phe Phe Leu Lys His Ile Phe Val Phe Gln Ala Ser His Pro Leu Ser
305                 310                 315                 320

Trp Gly Arg Ile Leu Phe Ile Gly Gly Ile Thr Ala Pro Thr Val Arg
                325                 330                 335

Gln Tyr Tyr Ala Tyr Leu Thr Asp Thr Gln Cys Lys Arg Val Gly Thr
            340                 345                 350

Gln Cys Trp Val Phe Gly Val Ile Gly Phe Leu Glu Ala Ile Val Cys
        355                 360                 365

Ile Lys Phe Gly Gln Asp Leu Phe Ser Lys Thr Gln Ile Leu Tyr Val
    370                 375                 380

Val Leu Trp Leu Leu Cys Val Ala Phe Thr Thr Phe Leu Cys Leu Tyr
385                 390                 395                 400

Gly Met Ile Trp Tyr Ala Glu His Tyr Gly His Arg Glu Lys Thr Tyr
                405                 410                 415

Ser Glu Cys Glu Asp Gly Thr Tyr Ser Pro Glu Ile Ser Trp His His
            420                 425                 430

Arg Lys Gly Thr Lys Gly Ser Glu Asp Ser Pro Pro Lys His Ala Gly
        435                 440                 445

Asn Asn Glu Ser His Ser Ser Arg Arg Arg Asn Arg His Ser Lys Ser
    450                 455                 460

Lys Val Thr Asn Gly Val Gly Lys Lys 
465                 470



<210> 2017
<211> 110
<212> PRT
<213> Homo sapiens

<400> 2017
Met Pro Ala Cys Ile Leu Glu Asp Val Glu Ile Ser Phe Arg Gln Lys
  1               5                  10                  15

Trp Ser Ile Asn Ser Asp Thr Leu Leu Gly Cys Leu Thr Leu Phe Ile
             20                  25                  30

Ser Ala Phe Phe Ala Ser Glu Thr Trp Gln Lys Leu Val Ser Gln Ser
         35                  40                  45

Thr Ala Phe Leu Thr Met Cys Gly Val Thr Tyr Ala Trp Tyr Met Pro
     50                  55                  60

Leu Leu Leu Leu Lys Phe Tyr Ser Leu Leu Leu Ala Gln Val Leu Leu
 65                  70                  75                  80

Asn Pro Phe Leu Met Cys Thr Gly Trp Arg Lys Asn Tyr Ser Gln His
                 85                  90                  95

Phe Glu Arg Lys Val Phe Arg Asn Asn Ile Asn Trp His Tyr 
            100                 105                 110



<210> 2018
<211> 151
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2018
Met Pro Phe Gln Val Pro Glu Leu Pro Val Gly Asn Glu Thr Gly Leu
  1               5                  10                  15

Leu Ala Ala Ser Ser Lys Thr Arg Ala Leu Cys Glu Pro Leu Pro Tyr
             20                  25                  30

Tyr Thr Cys Ser Cys Val Leu Gly Phe Ile Ala Cys Ser Val Phe Leu
         35                  40                  45

Arg Met Ser Leu Glu Pro Lys Val Val Leu Leu Thr Val Ala Leu Val
     50                  55                  60

Ala Tyr Leu Val Leu Phe Asn Leu Ser Pro Cys Trp Gln Trp Asp Cys
 65                  70                  75                  80

Cys Gly Gln Gly Leu Gly Asn Leu Thr Lys Pro Asn Gly Thr Thr Ser
                 85                  90                  95

Gly Thr Pro Ser Cys Ser Trp Lys Asp Leu Lys Thr Met Thr Asn Phe
            100                 105                 110

Tyr Leu Val Leu Phe Tyr Ile His Pro Ala Leu His Ser Xaa Arg Gln
        115                 120                 125

Ile Gly Leu Xaa Met Ala Ala Trp Xaa Cys Xaa Trp Lys Lys Asn Phe
    130                 135                 140

Lys Lys Glu His Glu Glu Phe 
145                 150



<210> 2019
<211> 129
<212> PRT
<213> Homo sapiens

<400> 2019
Met Ser Ile Ser Arg Ala Val Leu Gly Glu Lys Glu Gly Gly Leu Gly
  1               5                  10                  15

Ser Val Ala Pro Cys Gln Pro Ala Leu Arg Glu Asp Arg Val Ser His
             20                  25                  30

Ala Arg Met Ala Gly His Val Ser Val Leu Val Ser His Phe Pro Pro
         35                  40                  45

Ser Val Thr Tyr Leu Gly Ile Pro Gln Gly Leu Leu Glu Cys Asp Cys
     50                  55                  60

Pro Leu Pro Ser Cys Leu Gly Tyr Lys Ser Trp Pro Tyr Val Pro Ala
 65                  70                  75                  80

Val Arg Gly Ser Gly Asn Pro Thr Gln Pro Pro Val Leu Gly Trp Ser
                 85                  90                  95

Val Ser Ile His Pro Leu Val Val Ile Glu Ala Ala Leu Pro Val Leu
            100                 105                 110

Gly Glu Asp Ile Trp Ala Thr Arg Ala Pro Leu Ala Pro Ser Arg Arg
        115                 120                 125

Lys 




<210> 2020
<211> 171
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2020
Met Ala Pro Ala Ala Asp Arg Glu Gly Tyr Trp Gly Pro Thr Thr Ser
  1               5                  10                  15

Thr Leu Asp Trp Cys Glu Glu Asn Tyr Ser Val Thr Trp Tyr Ile Ala
             20                  25                  30

Glu Phe Trp Asn Thr Val Ser Asn Leu Ile Met Ile Ile Pro Pro Met
         35                  40                  45

Phe Gly Ala Ile Gln Ser Val Arg Asp Gly Leu Xaa Lys Arg Tyr Ile
     50                  55                  60

Ala Ser Tyr Leu Ala Leu Thr Val Val Gly Met Gly Ser Trp Cys Phe
 65                  70                  75                  80

His Met Thr Leu Lys Tyr Glu Met Gln Leu Leu Asp Glu Leu Pro Met
                 85                  90                  95

Ile Tyr Ser Cys Cys Ile Phe Val Tyr Cys Met Phe Glu Cys Phe Lys
            100                 105                 110

Ile Lys Asn Ser Val Asn Tyr His Leu Leu Phe Thr Leu Val Leu Phe
        115                 120                 125

Ser Leu Ile Val Thr Thr Val Tyr Leu Lys Val Lys Glu Pro Ile Phe
    130                 135                 140

His Gln Val Ile Phe Cys Lys Leu Leu His Ile Arg Leu Phe Thr Ile
145                 150                 155                 160

His Gly Cys Phe Val Ile Ser Leu Ala Xaa Lys 
                165                 170



<210> 2021
<211> 224
<212> PRT
<213> Homo sapiens

<400> 2021
Met Val Cys Leu Val Leu Leu Asn His Pro Lys Glu Leu Asn Met Ala
  1               5                  10                  15

Lys Gln Met Val Lys Ala Ser Arg Leu Phe Tyr Phe Gly Ser Ala Arg
             20                  25                  30

Ser Pro Leu Thr Cys Asp Leu Cys Cys Pro Ser Arg Trp Ser Gln Ala
         35                  40                  45

Ile Gln Pro Cys Pro Leu Pro Leu Cys Pro Asp Ala Ser Gly Ala Arg
     50                  55                  60

Leu Phe Arg Leu Ala Leu Thr Ser Gly Arg Gln Pro Thr Leu Arg Asp
 65                  70                  75                  80

Val Ala Asn Thr Thr Pro Pro Val Leu Ser Val Gly Arg Ala Glu Ala
                 85                  90                  95

Ala Trp Glu Ala Arg Gly Asp Arg Lys Arg Ala Leu Ser Ser Ser Glu
            100                 105                 110

Lys Arg Ile Cys His Gln Ile Glu Phe Arg Pro Leu Ser Leu Phe Gly
        115                 120                 125

Arg Met Val Gln Ile Gln Ile Lys Val Val Thr Gln Pro Glu Met Ser
    130                 135                 140

Gly Lys Ala Phe Cys Arg Glu Asn Val Pro Pro Pro Ala Ile Cys Ser
145                 150                 155                 160

Gln Val Cys Ala Thr Arg Gln Pro Ser Arg Asn Ile Val Trp Ile Leu
                165                 170                 175

Lys Met Cys Leu Phe Leu Phe Leu Asn His Phe Ile Thr Tyr Phe Leu
            180                 185                 190

Ile Tyr Phe Val Met Ser Cys Phe Glu Val Leu Leu Leu Ser Leu Leu
        195                 200                 205

Ser Phe Pro Leu Phe Leu Ser Leu Ile Tyr Phe Val Lys Val Val His
    210                 215                 220






<210> 2022
<211> 304
<212> PRT
<213> Homo sapiens

<400> 2022
Met Leu Val Val Ser Trp Phe Trp Met His Trp Leu Phe Leu Gly Cys
  1               5                  10                  15

Asn Phe Lys Glu Thr Cys Ser Leu Ser Lys Lys Lys Lys Thr Lys Arg
             20                  25                  30

Glu Gln Leu Ser Glu Lys Arg Ile Gln Glu Glu Tyr Glu Lys Leu Gly
         35                  40                  45

Asp Ile Ser Tyr Pro Glu Met Val Thr Gly Phe Phe Phe Ile Leu Met
     50                  55                  60

Thr Val Leu Trp Phe Thr Arg Glu Pro Gly Phe Val Pro Gly Trp Asp
 65                  70                  75                  80

Ser Phe Phe Glu Lys Lys Gly Tyr Arg Thr Asp Ala Thr Val Ser Val
                 85                  90                  95

Phe Leu Gly Phe Leu Leu Phe Leu Ile Pro Ala Lys Lys Pro Cys Phe
            100                 105                 110

Gly Lys Lys Asn Asp Gly Glu Asn Gln Glu His Ser Leu Gly Thr Glu
        115                 120                 125

Pro Ile Ile Thr Trp Lys Asp Phe Gln Lys Thr Met Pro Trp Glu Ile
    130                 135                 140

Val Ile Leu Val Gly Gly Gly Tyr Ala Leu Ala Ser Gly Ser Lys Ser
145                 150                 155                 160

Ser Gly Leu Ser Thr Trp Ile Gly Asn Gln Met Leu Ser Leu Ser Ser
                165                 170                 175

Leu Pro Pro Trp Ala Val Thr Leu Leu Ala Cys Ile Leu Val Ser Ile
            180                 185                 190

Val Thr Glu Phe Val Ser Asn Pro Ala Thr Ile Thr Ile Phe Leu Pro
        195                 200                 205

Ile Leu Cys Ser Leu Ser Glu Thr Leu His Ile Asn Pro Leu Tyr Thr
    210                 215                 220

Leu Ile Pro Val Thr Met Cys Ile Ser Phe Ala Val Met Leu Pro Val
225                 230                 235                 240

Gly Asn Pro Pro Asn Ala Ile Val Phe Ser Tyr Gly His Cys Gln Ile
                245                 250                 255

Lys Asp Met Val Lys Ala Gly Leu Gly Val Asn Val Ile Gly Leu Val
            260                 265                 270

Ile Val Met Val Ala Ile Asn Thr Trp Gly Val Ser Leu Phe His Leu
        275                 280                 285

Asp Thr Tyr Pro Ala Trp Ala Arg Val Ser Asn Ile Thr Asp Gln Ala
    290                 295                 300






<210> 2023
<211> 124
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2023
Met Val Cys His Leu Leu Arg Met Trp Arg Phe Leu Phe Tyr Ser Trp
  1               5                  10                  15

Asn Trp Ile Ala Val Ala Ser Gly Arg His Lys Ala Phe Cys Ser Val
             20                  25                  30

Leu Tyr Pro Arg Gln Ser Cys Cys Val Xaa Ser Thr Cys Phe Leu Met
         35                  40                  45

Gly Pro Val Lys Gln Leu Lys Lys Met Phe Glu Ala Thr Arg Leu Leu
     50                  55                  60

Ala Thr Ile Val Met Leu Leu Cys Phe Ile Phe Thr Leu Cys Ala Ala
 65                  70                  75                  80

Leu Trp Trp His Lys Lys Gly Leu Ala Val Leu Phe Cys Ile Leu Gln
                 85                  90                  95

Phe Leu Ser Met Thr Trp Tyr Ser Leu Ser Tyr Ile Pro Tyr Ala Arg
            100                 105                 110

Asp Ala Val Ile Lys Cys Cys Ser Ser Leu Leu Ser 
        115                 120



<210> 2024
<211> 135
<212> PRT
<213> Homo sapiens

<400> 2024
Met Ile Arg Glu Gly Thr Thr Gly Val Cys Phe Pro Phe Val Leu Ser
  1               5                  10                  15

Val Arg Gln Arg Glu Thr Leu Val Gln His Phe Gln Ser Val Gly Gly
             20                  25                  30

Ser Val Gly Ser Arg Asp Thr Phe Arg Trp Tyr Gly Ala Cys Ile Lys
         35                  40                  45

Trp His Lys Ile Arg Ala Arg Lys Arg Cys Pro Ser Gln Phe Ser Gln
     50                  55                  60

Ser Phe Tyr Ala Glu Lys Ile Ser Ala Gly Cys Gln His Val Pro Met
 65                  70                  75                  80

Pro Val Glu Asp Met Pro Thr Ser Pro Leu Pro Arg Glu Gln Asp Leu
                 85                  90                  95

Gly Leu Gly Gln Val Glu Lys Ile Pro Asp Phe Phe Ser Thr Val Phe
            100                 105                 110

Val Leu Met Val Tyr Phe Tyr Trp Leu Leu Tyr Cys Leu Gly Gln Val
        115                 120                 125

Val Val Ala Phe Tyr Leu Leu 
    130                 135



<210> 2025
<211> 368
<212> PRT
<213> Homo sapiens

<400> 2025
Met Leu Phe Trp Val Ile Ser Met Val Met Val Ala Val Gly Val Tyr
  1               5                  10                  15

Ala Arg Leu Met Lys His Ala Glu Ala Ala Leu Ala Cys Leu Ala Val
             20                  25                  30

Asp Pro Ala Ile Leu Leu Ile Val Val Gly Val Leu Met Phe Leu Leu
         35                  40                  45

Thr Phe Cys Gly Cys Ile Gly Ser Leu Arg Glu Asn Ile Cys Leu Leu
     50                  55                  60

Gln Thr Phe Ser Leu Cys Leu Thr Ala Val Phe Leu Leu Gln Leu Ala
 65                  70                  75                  80

Ala Gly Ile Leu Gly Phe Val Phe Ser Asp Lys Ala Arg Gly Lys Val
                 85                  90                  95

Ser Glu Ile Ile Asn Asn Ala Ile Val His Tyr Arg Asp Asp Leu Asp
            100                 105                 110

Leu Gln Asn Leu Ile Asp Phe Gly Gln Lys Lys Phe Ser Cys Cys Gly
        115                 120                 125

Gly Ile Ser Tyr Lys Asp Trp Ser Gln Asn Met Tyr Phe Asn Cys Ser
    130                 135                 140

Glu Asp Asn Pro Ser Arg Glu Arg Cys Ser Val Pro Tyr Ser Cys Cys
145                 150                 155                 160

Leu Pro Thr Pro Asp Gln Ala Val Ile Asn Thr Met Cys Gly Gln Gly
                165                 170                 175

Met Gln Ala Phe Asp Tyr Leu Glu Ala Ser Lys Val Ile Tyr Thr Asn
            180                 185                 190

Gly Cys Ile Asp Lys Leu Val Asn Trp Ile His Ser Asn Leu Phe Leu
        195                 200                 205

Leu Gly Gly Val Ala Leu Gly Leu Ala Ile Pro Gln Leu Val Gly Ile
    210                 215                 220

Leu Leu Ser Gln Ile Leu Val Asn Gln Ile Lys Asp Gln Ile Ser Tyr
225                 230                 235                 240

Ser Ser Thr Thr Ser Ser Thr Gly Leu Thr His Gly Thr Glu Asn Pro
                245                 250                 255

Ser Cys Thr Ser Ser Pro Trp Lys Leu Ala Ser Leu Ile Asn Glu Gln
            260                 265                 270

Gln Trp Val Leu Lys Ala Ala Pro Asn Gly Asp Leu Asp Ser Ser Pro
        275                 280                 285

Pro Val Thr Ala Gln Trp Glu Glu Ala Asn Ser Arg Trp Ala Glu Gly
    290                 295                 300

Arg Val His Arg Trp Leu Gln Ser Gln Glu Asp Ala Pro Pro Leu Pro
305                 310                 315                 320

His Pro Ser Pro Gln His Cys Ala Arg Val Ile Pro Leu Ser Val Trp
                325                 330                 335

Val Tyr Val Phe Ser Phe Val Trp Glu Thr Ala Val Ala Gln Arg Val
            340                 345                 350

Gly Gly Thr Ala Ala Ala Phe Ser Pro Arg His Cys His His Gln Leu
        355                 360                 365






<210> 2026
<211> 245
<212> PRT
<213> Homo sapiens

<400> 2026
Met Asn Gly Arg Ala Asp Phe Arg Glu Pro Asn Ala Glu Val Pro Arg
  1               5                  10                  15

Pro Ile Pro His Ile Gly Pro Asp Tyr Ile Pro Thr Glu Glu Glu Arg
             20                  25                  30

Arg Val Phe Ala Glu Cys Asn Asp Glu Ser Phe Trp Phe Arg Ser Val
         35                  40                  45

Pro Leu Ala Ala Thr Ser Met Leu Ile Thr Gln Gly Leu Ile Ser Lys
     50                  55                  60

Gly Ile Leu Ser Ser His Pro Lys Tyr Gly Ser Ile Pro Lys Leu Ile
 65                  70                  75                  80

Leu Ala Cys Ile Met Gly Tyr Phe Ala Gly Lys Leu Ser Tyr Val Lys
                 85                  90                  95

Thr Cys Gln Glu Lys Phe Lys Lys Leu Glu Asn Ser Pro Leu Gly Glu
            100                 105                 110

Ala Leu Arg Ser Gly Gln Ala Arg Arg Ser Ser Pro Pro Gly His Tyr
        115                 120                 125

Tyr Gln Lys Ser Lys Tyr Asp Ser Ser Val Ser Gly Gln Ser Ser Phe
    130                 135                 140

Val Thr Ser Pro Ala Ala Asp Asn Ile Glu Met Leu Pro His Tyr Glu
145                 150                 155                 160

Pro Ile Pro Phe Ser Ser Ser Met Asn Glu Ser Ala Pro Thr Gly Ile
                165                 170                 175

Thr Asp His Ile Val Gln Gly Pro Asp Pro Asn Leu Glu Glu Ser Pro
            180                 185                 190

Lys Arg Lys Asn Ile Thr Tyr Glu Glu Leu Arg Asn Lys Asn Arg Glu
        195                 200                 205

Ser Tyr Glu Val Ser Leu Thr Gln Lys Thr Asp Pro Ser Val Arg Pro
    210                 215                 220

Met His Glu Arg Val Pro Lys Lys Glu Val Lys Val Asn Lys Tyr Gly
225                 230                 235                 240

Asp Thr Trp Asp Glu 
                245



<210> 2027
<211> 185
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2027
Met Ala Gly Pro Arg Pro Xaa Trp Arg Asp Gln Leu Leu Phe Met Ser
  1               5                  10                  15

Ile Ile Val Leu Val Ile Val Val Ile Cys Leu Met Leu Tyr Ala Leu
             20                  25                  30

Leu Trp Glu Ala Gly Asn Leu Thr Asp Leu Pro Asn Leu Arg Ile Gly
         35                  40                  45

Phe Tyr Asn Phe Cys Leu Trp Asn Glu Asp Thr Ser Thr Leu Gln Cys
     50                  55                  60

His Gln Phe Pro Glu Leu Glu Ala Leu Gly Val Pro Arg Val Gly Leu
 65                  70                  75                  80

Gly Leu Ala Arg Leu Gly Val Tyr Gly Ser Leu Val Leu Thr Leu Phe
                 85                  90                  95

Ala Pro Gln Pro Leu Leu Leu Ala Gln Cys Asn Ser Asp Glu Arg Ala
            100                 105                 110

Trp Arg Leu Ala Val Gly Phe Leu Ala Val Ser Ser Val Leu Leu Ala
        115                 120                 125

Gly Gly Leu Gly Leu Phe Leu Ser Tyr Val Trp Lys Trp Val Arg Leu
    130                 135                 140

Ser Leu Pro Gly Pro Gly Phe Leu Ala Leu Gly Ser Ala Gln Ala Leu
145                 150                 155                 160

Leu Ile Leu Leu Leu Ile Ala Met Ala Val Phe Pro Leu Arg Ala Glu
                165                 170                 175

Arg Ala Glu Ser Lys Leu Glu Ser Cys 
            180                 185



<210> 2028
<211> 149
<212> PRT
<213> Homo sapiens

<400> 2028
Met Gly Phe Arg Leu Glu Gly Ile Phe Pro Ala Ala Leu Leu Pro Leu
  1               5                  10                  15

Leu Leu Thr Met Ile Leu Phe Leu Gly Pro Leu Met Gln Leu Ser Met
             20                  25                  30

Asp Cys Pro Cys Asp Leu Ala Asp Gly Leu Lys Val Val Leu Ala Pro
         35                  40                  45

Arg Ser Trp Ala Arg Cys Leu Thr Asp Met Arg Trp Leu Arg Asn Gln
     50                  55                  60

Val Ile Ala Pro Leu Thr Glu Glu Leu Val Phe Arg Ala Cys Met Leu
 65                  70                  75                  80

Pro Met Leu Ala Pro Cys Met Gly Leu Gly Leu Leu Cys Ser Pro Ala
                 85                  90                  95

Arg Ser Phe Leu Glu Leu Pro Ile Phe Thr Ile Leu Leu Ser Ser Cys
            100                 105                 110

Val Ser Ala Arg Ala Ala Trp Gly Thr Ser Ser Cys Leu Leu Arg Ser
        115                 120                 125

Ser Ser Pro Thr Gln Leu Ser Ser Val Pro Thr Leu Leu Ser Ser Ser
    130                 135                 140

Ser Ala Gln Asp Thr 
145



<210> 2029
<211> 212
<212> PRT
<213> Homo sapiens

<400> 2029
Met Glu Tyr Phe Phe Pro Pro Pro Phe Leu Cys Phe Pro Leu Pro Val
  1               5                  10                  15

Ser Pro Pro Ser His Leu Phe Leu Ser Phe Pro Ile Pro Cys Thr Leu
             20                  25                  30

Thr Ser Ser Trp Met His Leu Leu Pro Ser Leu Ser Ser Cys Cys Phe
         35                  40                  45

Leu Pro Val Leu Phe Cys Cys Pro His Pro Val Phe Thr Pro Glu Leu
     50                  55                  60

Phe Leu Phe Phe Phe Ser Phe Phe Phe Phe Phe Phe Leu Arg Arg Ile
 65                  70                  75                  80

Leu Thr Leu Trp Pro Arg Leu Glu Arg Ser Gly Ala Ile Ser Thr His
                 85                  90                  95

Cys Asn Pro Arg Leu Leu Gly Ser Ser Asp Ser Pro Ala Pro Ala Ser
            100                 105                 110

Gln Val Ala Gly Arg Thr Gly Val Ser Cys Arg Thr Gln Pro Val Ser
        115                 120                 125

Leu Phe Pro Leu Phe Phe Phe Leu Ile Ser Phe Leu Gly Cys Leu Ser
    130                 135                 140

Ala Phe Leu Ser Ala Cys Phe Ala Ser Thr Phe Ser Cys Val Leu Gly
145                 150                 155                 160

Ser Pro Glu Thr Ser Phe Ser Pro Cys Leu His Pro Pro Pro Lys Val
                165                 170                 175

Leu Ser Ser His Pro His Pro Leu Gln Pro Ser Met Pro Gln Pro Pro
            180                 185                 190

Lys Gly Pro His Cys Gln Ser Ile Ala Ala Ser Leu His Pro Met Glu
        195                 200                 205

Ala Met Ser Pro 
    210



<210> 2030
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2030
Met Lys Arg Pro Val Ser Thr Leu Pro Ser Leu Thr Ala Asp Ser Ala
  1               5                  10                  15

Met Pro Leu Pro Arg Ser Ala Phe Glu Asp Cys Asp Leu His Gln Glu
             20                  25                  30

Val Leu Leu Thr Pro Val Gly Lys Ile Ser Pro Ser Phe Cys Leu Glu
         35                  40                  45

Cys Pro Val Phe Asp Leu Ala Ala Gly Val Glu Pro Ser Pro Arg Pro
     50                  55                  60

Pro Gly Xaa Leu Pro Leu Trp Leu Ser Arg Asn Arg Met Trp Leu Pro
 65                  70                  75                  80

Trp Pro Asn Val Val Leu Leu Ser Pro Thr Xaa Ala Pro Gln Leu Leu
                 85                  90                  95

Ser Ser Ser Gly Pro Cys Val Trp Leu Val Phe Ala Gly Leu Ser Leu
            100                 105                 110

Cys Ser Gly Ile Ala Leu Pro Leu 
        115                 120



<210> 2031
<211> 120
<212> PRT
<213> Homo sapiens

<400> 2031
Met Cys Leu Gly Phe Leu Arg Gly Phe Pro Glu Ser Val Pro Asn Ser
  1               5                  10                  15

Asp Val Phe Ile Arg Asn Thr Arg Gly Pro Ser Glu Val Ile Pro Ala
             20                  25                  30

Pro Gly Lys Leu Thr Trp His Gly Ala Pro Phe Cys Pro Gly Leu Phe
         35                  40                  45

His Pro Ile Cys Pro Gly Pro Arg Ala Cys Pro Val Trp Ser Ser Leu
     50                  55                  60

Ser Cys Leu Val Cys His His Val Met Leu Gly Trp Leu Val Phe Ala
 65                  70                  75                  80

Ala Ser Leu Pro Lys Leu Thr Asp Val Ser Ala Arg Asp His Gln Leu
                 85                  90                  95

Pro Ser Arg Met Thr Val Leu Ser Phe Lys Val Gln Arg Leu Pro Phe
            100                 105                 110

Gln Ser Gly Pro Ser Pro Thr Ser 
        115                 120



<210> 2032
<211> 195
<212> PRT
<213> Homo sapiens

<400> 2032
Met Val Ile Ser Ser Phe Gly Gly Leu Ile Leu Ser Lys Thr Val Ser
  1               5                  10                  15

Lys Gln Gln Tyr Lys Gly Met Ala Ile Phe Thr Pro Val Ile Cys Gly
             20                  25                  30

Val Gly Gly Asn Leu Val Ala Ile Gln Thr Ser Arg Ile Ser Thr Tyr
         35                  40                  45

Leu His Met Trp Ser Ala Pro Gly Val Leu Pro Leu Gln Met Lys Lys
     50                  55                  60

Phe Trp Pro Asn Pro Cys Ser Thr Phe Cys Thr Ser Glu Ile Asn Ser
 65                  70                  75                  80

Met Ser Ala Arg Val Leu Leu Leu Leu Val Val Pro Gly His Leu Ile
                 85                  90                  95

Phe Phe Tyr Ile Ile Tyr Leu Val Glu Gly Gln Ser Val Ile Asn Ser
            100                 105                 110

Gln Thr Phe Val Val Leu Tyr Leu Leu Ala Gly Leu Ile Gln Val Thr
        115                 120                 125

Ile Leu Leu Tyr Leu Ala Glu Val Met Val Arg Leu Thr Trp His Gln
    130                 135                 140

Ala Leu Asp Pro Asp Asn His Cys Ile Pro Tyr Leu Thr Gly Leu Gly
145                 150                 155                 160

Asp Leu Leu Gly Thr Gly Leu Leu Ala Leu Cys Phe Phe Thr Asp Trp
                165                 170                 175

Leu Leu Lys Ser Lys Ala Glu Leu Gly Gly Ile Ser Glu Leu Ala Ser
            180                 185                 190

Gly Pro Pro 
        195



<210> 2033
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2033
Met Gly Arg Glu Trp Pro Arg Pro Ala Pro Ser Leu Leu Pro Ala Phe
  1               5                  10                  15

Pro Glu Leu Val Pro Gly Ser Ala Gln Arg Gly Val Pro Ala Ile Ser
             20                  25                  30

Pro Cys Ile Cys Gln Ala Pro Lys Thr Pro Ser Leu Val Cys Leu Pro
         35                  40                  45

Ala Arg Pro Pro Arg Ser Cys Leu Ser Val Pro Asp Arg Val Ser Leu
     50                  55                  60

Leu Cys Thr Leu Arg Ser Leu Leu Phe Leu Leu Ala Leu Ser Ala Arg
 65                  70                  75                  80

Gly Pro Leu Pro Gln Trp Gly Arg Trp Arg Ser Leu Ala Pro Gly Trp
                 85                  90                  95

Ala Asp Arg Ala Pro Ser Trp Val Arg Arg Ser His Xaa Leu Lys Trp
            100                 105                 110

Arg Ala Leu Cys Pro Gly Gly Thr Ala Arg Cys Val Asp Arg Arg Cys
        115                 120                 125

His Glu Pro Phe Pro Glu Pro Gln Gly 
    130                 135



<210> 2034
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2034
Met Tyr Ile Met Leu His Ser Ile Thr Val Lys Ser Pro Leu Cys Pro
  1               5                  10                  15

Leu Pro Gln Lys Ser Phe Ser Leu Val Ser Lys Leu Gly Lys Arg Arg
             20                  25                  30

Ser Leu Leu Leu Pro Val Gln Phe Val Leu Gly Gln Gln Leu Glu Val
         35                  40                  45

Leu Gly Ala Gln Pro Val Gln Leu Gln Leu Gln Leu Pro His Thr Arg
     50                  55                  60

Val Val Ala Thr Gln Pro Leu Ala Leu Gln Pro Gln Pro Val Val Leu
 65                  70                  75                  80

Val Leu His Ala Arg Glu Ala Leu Leu Gln Phe Gln Val Leu Leu Asp
                 85                  90                  95

Glu Leu Leu Leu Ala His Val Leu Gln Ala Leu Arg Val Val Pro Leu
            100                 105                 110

Val Arg Leu Arg Glu Val Pro Leu Gln Lys Leu Ala Ala Val Pro Ser
        115                 120                 125

His Pro Ile Ala Ala Pro Ile Leu Leu Thr Pro Phe Phe His Glu Val
    130                 135                 140

Val Ile Ala Gly Val Val Gly Phe Ala Ala Xaa Arg Leu Glu Xaa Arg
145                 150                 155                 160

Pro Val Leu Arg Ser Gly Ser Ser Trp Ser 
                165                 170



<210> 2035
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (44)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2035
Met Gly Lys Arg Gln Arg Ala Leu Ser Val Pro Leu Lys Thr Asn Thr
  1               5                  10                  15

Leu Asn Ile Pro Cys Asp Leu Glu Gln Cys Gly Ser Phe His Ser Thr
             20                  25                  30

Gly Pro Phe Ile Gly Gly Leu Asn Val Ser Leu Xaa Ser Val Thr Asn
         35                  40                  45

Ser Leu Leu Ser Ala Ser Leu Ser Val Asn Trp Met Lys Arg Ala Leu
     50                  55                  60

Met Pro Phe Arg Leu Leu Glu Ala Ile Asp Leu Asp Lys Pro Ser Lys
 65                  70                  75                  80

Met Gly Val Leu Pro Gly Leu Phe Pro Phe Pro Pro Ser Leu Ala Thr
                 85                  90                  95

Val Leu Gly Val Trp Gln Leu Phe Gly Phe Phe Phe Phe Leu Gln Leu
            100                 105                 110

Cys Val Cys Val Phe Val 
        115



<210> 2036
<211> 377
<212> PRT
<213> Homo sapiens

<400> 2036
Met Glu Ala Leu Leu Leu Gly Ala Gly Leu Leu Leu Gly Ala Tyr Val
  1               5                  10                  15

Leu Val Tyr Tyr Asn Leu Val Lys Ala Pro Pro Cys Gly Gly Met Gly
             20                  25                  30

Asn Leu Arg Gly Arg Thr Ala Val Val Thr Gly Ala Asn Ser Gly Ile
         35                  40                  45

Gly Lys Met Thr Ala Leu Glu Leu Ala Arg Arg Gly Ala Arg Val Val
     50                  55                  60

Leu Ala Cys Arg Ser Gln Glu Arg Gly Glu Ala Ala Ala Phe Asp Leu
 65                  70                  75                  80

Arg Gln Glu Ser Gly Asn Asn Glu Val Ile Phe Met Ala Leu Asp Leu
                 85                  90                  95

Ala Ser Leu Ala Ser Val Arg Ala Phe Ala Thr Ala Phe Leu Ser Ser
            100                 105                 110

Glu Pro Arg Leu Asp Ile Leu Ile His Asn Ala Gly Ile Ser Ser Cys
        115                 120                 125

Gly Arg Thr Arg Glu Ala Phe Asn Leu Leu Leu Arg Val Asn His Ile
    130                 135                 140

Gly Pro Phe Leu Leu Thr His Leu Leu Leu Pro Cys Leu Lys Ala Cys
145                 150                 155                 160

Ala Pro Ser Arg Val Val Val Val Ala Ser Ala Ala His Cys Arg Gly
                165                 170                 175

Arg Leu Asp Phe Lys Arg Leu Asp Arg Pro Val Val Gly Trp Arg Gln
            180                 185                 190

Glu Leu Arg Ala Tyr Ala Asp Thr Lys Leu Ala Asn Val Leu Phe Ala
        195                 200                 205

Arg Glu Leu Ala Asn Gln Leu Glu Ala Thr Gly Val Thr Cys Tyr Ala
    210                 215                 220

Ala His Pro Gly Pro Val Asn Ser Glu Leu Phe Leu Arg His Val Pro
225                 230                 235                 240

Gly Trp Leu Arg Pro Leu Leu Arg Pro Leu Ala Trp Leu Val Leu Arg
                245                 250                 255

Ala Pro Arg Gly Gly Ala Gln Thr Pro Leu Tyr Cys Ala Leu Gln Glu
            260                 265                 270

Gly Ile Glu Pro Leu Ser Gly Arg Tyr Phe Ala Asn Cys His Val Glu
        275                 280                 285

Glu Val Pro Pro Ala Ala Arg Asp Asp Arg Ala Ala His Arg Leu Trp
    290                 295                 300

Glu Ala Ser Lys Arg Leu Ala Gly Leu Gly Pro Gly Glu Asp Ala Glu
305                 310                 315                 320

Pro Asp Glu Asp Pro Gln Ser Glu Asp Ser Glu Ala Pro Ser Ser Leu
                325                 330                 335

Ser Thr Pro His Pro Glu Glu Pro Thr Val Ser Gln Pro Tyr Pro Ser
            340                 345                 350

Pro Gln Ser Ser Pro Asp Leu Ser Lys Met Thr His Arg Ile Gln Ala
        355                 360                 365

Lys Val Glu Pro Glu Ile Gln Leu Ser 
    370                 375



<210> 2037
<211> 354
<212> PRT
<213> Homo sapiens

<400> 2037
Met Asp Phe Ile Leu Glu Asp Met Asp Leu Ala Ala Asn Glu Ile Ser
  1               5                  10                  15

Ile Tyr Asp Lys Leu Ser Glu Thr Val Asp Leu Val Arg Gln Thr Gly
             20                  25                  30

His Gln Cys Gly Met Ser Glu Lys Ala Ile Glu Lys Phe Ile Arg Gln
         35                  40                  45

Leu Leu Glu Lys Asn Glu Pro Gln Arg Pro Pro Pro Gln Tyr Pro Leu
     50                  55                  60

Leu Ile Val Val Tyr Lys Val Leu Ala Thr Leu Gly Leu Ile Leu Leu
 65                  70                  75                  80

Thr Ala Tyr Phe Val Ile Gln Pro Phe Ser Pro Leu Ala Pro Glu Pro
                 85                  90                  95

Val Leu Ser Gly Ala His Thr Trp Arg Ser Leu Ile His His Ile Arg
            100                 105                 110

Leu Met Ser Leu Pro Ile Ala Lys Lys Tyr Met Ser Glu Asn Lys Gly
        115                 120                 125

Val Pro Leu His Gly Gly Asp Glu Asp Arg Pro Phe Pro Asp Phe Asp
    130                 135                 140

Pro Trp Trp Thr Asn Asp Cys Glu Gln Asn Glu Ser Glu Pro Ile Pro
145                 150                 155                 160

Ala Asn Cys Thr Gly Cys Ala Gln Lys His Leu Lys Val Met Leu Leu
                165                 170                 175

Glu Asp Ala Pro Arg Lys Phe Glu Arg Leu His Pro Leu Val Ile Lys
            180                 185                 190

Thr Gly Lys Pro Leu Leu Glu Glu Glu Ile Gln His Phe Leu Cys Gln
        195                 200                 205

Tyr Pro Glu Ala Thr Glu Gly Phe Ser Glu Gly Phe Phe Ala Lys Trp
    210                 215                 220

Trp Arg Cys Phe Pro Glu Arg Trp Phe Pro Phe Pro Tyr Pro Trp Arg
225                 230                 235                 240

Arg Pro Leu Asn Arg Ser Gln Met Leu Arg Glu Leu Phe Pro Val Phe
                245                 250                 255

Thr His Leu Pro Phe Pro Lys Asp Ala Ser Leu Asn Lys Cys Ser Phe
            260                 265                 270

Leu His Pro Glu Pro Val Val Gly Ser Lys Met His Lys Met Pro Asp
        275                 280                 285

Leu Phe Ile Ile Gly Ser Gly Glu Ala Met Leu Gln Leu Ile Pro Pro
    290                 295                 300

Phe Gln Cys Arg Arg His Cys Gln Ser Val Ala Met Pro Ile Glu Pro
305                 310                 315                 320

Gly Asp Ile Gly Tyr Val Asp Thr Thr His Trp Lys Val Tyr Val Ile
                325                 330                 335

Ala Arg Gly Val Gln Pro Leu Val Ile Cys Asp Gly Thr Ala Phe Ser
            340                 345                 350

Glu Leu 




<210> 2038
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2038
Met Glu Ala Gly Gly Phe Leu Asp Ser Leu Ile Tyr Gly Ala Cys Val
  1               5                  10                  15

Val Phe Thr Leu Gly Met Phe Ser Ala Gly Leu Ser Asp Leu Arg His
             20                  25                  30

Met Arg Met Thr Arg Ser Val Asp Asn Val Gln Phe Leu Pro Phe Leu
         35                  40                  45

Thr Thr Glu Val Asn Asn Leu Gly Trp Leu Ser Tyr Gly Ala Leu Lys
     50                  55                  60

Gly Asp Gly Ile Leu Ile Val Val Asn Thr Val Gly Ala Ala Leu Gln
 65                  70                  75                  80

Thr Leu Tyr Ile Leu Ala Tyr Leu His Tyr Cys Pro Arg Lys Ala Lys
                 85                  90                  95

Val Ile Gln Thr Lys Ser Thr Gln Cys Leu Ser Tyr Pro Leu Thr Ile
            100                 105                 110

Ala Thr Leu Leu Thr Ser Ala Ser Trp Cys Leu Tyr Gly Phe Arg Leu
        115                 120                 125

Arg Asp Pro Tyr Ile Met Xaa Ser Asn Phe Pro Gly Ile Val Thr Ser
    130                 135                 140

Phe Ile Arg Phe Trp Leu Phe Trp Lys Tyr Pro Gln Glu Gln Asp Arg
145                 150                 155                 160

Asn Tyr Trp Leu Leu Gln Thr 
                165



<210> 2039
<211> 716
<212> PRT
<213> Homo sapiens

<400> 2039
Met Phe Ser Leu Ser Ser Thr Val Gln Pro Gln Val Thr Val Pro Leu
  1               5                  10                  15

Ser His Leu Ile Asn Ala Phe His Thr Pro Lys Asn Thr Ser Val Ser
             20                  25                  30

Leu Ser Gly Val Ser Val Ser Gln Asn Gln His Arg Asp Val Val Pro
         35                  40                  45

Glu His Glu Ala Pro Ser Ser Glu Pro Ser Leu Asn Leu Arg Asp Leu
     50                  55                  60

Gly Leu Ser Glu Leu Lys Ile Gly Gln Ile Asp Gln Leu Val Glu Asn
 65                  70                  75                  80

Leu Leu Pro Gly Phe Cys Lys Gly Lys Asn Ile Ser Ser His Trp His
                 85                  90                  95

Thr Ser His Val Ser Ala Gln Ser Phe Phe Glu Asn Lys Tyr Gly Asn
            100                 105                 110

Leu Asp Ile Phe Ser Thr Leu Arg Ser Ser Cys Leu Tyr Arg His His
        115                 120                 125

Ser Arg Ala Leu Gln Ser Ile Cys Ser Asp Leu Gln Tyr Trp Pro Val
    130                 135                 140

Phe Ile Gln Ser Arg Gly Phe Lys Thr Leu Lys Ser Arg Thr Arg Arg
145                 150                 155                 160

Leu Gln Ser Thr Ser Glu Arg Leu Ala Glu Thr Gln Asn Ile Ala Pro
                165                 170                 175

Ser Phe Val Lys Gly Phe Leu Leu Arg Asp Arg Gly Ser Asp Val Glu
            180                 185                 190

Ser Leu Asp Lys Leu Met Lys Thr Lys Asn Ile Pro Glu Ala His Gln
        195                 200                 205

Asp Ala Phe Lys Thr Gly Phe Ala Glu Gly Phe Leu Lys Ala Gln Ala
    210                 215                 220

Leu Thr Gln Lys Thr Asn Asp Ser Leu Arg Arg Thr Arg Leu Ile Leu
225                 230                 235                 240

Phe Val Leu Leu Leu Phe Gly Ile Tyr Gly Leu Leu Lys Asn Pro Phe
                245                 250                 255

Leu Ser Val Arg Phe Arg Thr Thr Thr Gly Leu Asp Ser Ala Val Asp
            260                 265                 270

Pro Val Gln Met Lys Asn Val Thr Phe Glu His Val Lys Gly Val Glu
        275                 280                 285

Glu Ala Lys Gln Glu Leu Gln Glu Val Val Glu Phe Leu Lys Asn Pro
    290                 295                 300

Gln Lys Phe Thr Ile Leu Gly Gly Lys Leu Pro Lys Gly Ile Leu Leu
305                 310                 315                 320

Val Gly Pro Pro Gly Thr Gly Lys Thr Leu Leu Ala Arg Ala Val Ala
                325                 330                 335

Gly Glu Ala Asp Val Pro Phe Tyr Tyr Ala Ser Gly Ser Glu Phe Asp
            340                 345                 350

Glu Met Phe Val Gly Val Gly Ala Ser Arg Ile Arg Asn Leu Phe Arg
        355                 360                 365

Glu Ala Lys Ala Asn Ala Pro Cys Val Ile Phe Ile Asp Glu Leu Asp
    370                 375                 380

Ser Val Gly Gly Lys Arg Ile Glu Ser Pro Met His Pro Tyr Ser Arg
385                 390                 395                 400

Gln Thr Ile Asn Gln Leu Leu Ala Glu Met Asp Gly Phe Lys Pro Asn
                405                 410                 415

Glu Gly Val Ile Ile Ile Gly Ala Thr Asn Phe Pro Glu Ala Leu Asp
            420                 425                 430

Asn Ala Leu Ile Arg Pro Gly Arg Phe Asp Met Gln Val Thr Val Pro
        435                 440                 445

Arg Pro Asp Val Lys Gly Arg Thr Glu Ile Leu Lys Trp Tyr Leu Asn
    450                 455                 460

Lys Ile Lys Phe Asp Gln Ser Val Asp Pro Glu Ile Ile Ala Arg Gly
465                 470                 475                 480

Thr Val Gly Phe Ser Gly Ala Glu Leu Glu Asn Leu Val Asn Gln Ala
                485                 490                 495

Ala Leu Lys Ala Ala Val Asp Gly Lys Glu Met Val Thr Met Lys Glu
            500                 505                 510

Leu Glu Phe Ser Lys Asp Lys Ile Leu Met Gly Pro Glu Arg Arg Ser
        515                 520                 525

Val Glu Ile Asp Asn Lys Asn Lys Thr Ile Thr Ala Tyr His Glu Ser
    530                 535                 540

Gly His Ala Ile Ile Ala Tyr Tyr Thr Lys Asp Ala Met Pro Ile Asn
545                 550                 555                 560

Lys Ala Thr Ile Met Pro Arg Gly Pro Thr Leu Gly His Val Ser Leu
                565                 570                 575

Leu Pro Glu Asn Asp Arg Trp Asn Glu Thr Arg Ala Gln Leu Leu Ala
            580                 585                 590

Gln Met Asp Val Ser Met Gly Gly Arg Val Ala Glu Glu Leu Ile Phe
        595                 600                 605

Gly Thr Asp His Ile Thr Thr Gly Ala Ser Ser Asp Phe Asp Asn Ala
    610                 615                 620

Thr Lys Ile Ala Lys Arg Met Val Thr Lys Phe Gly Met Ser Glu Lys
625                 630                 635                 640

Leu Gly Val Met Thr Tyr Ser Asp Thr Gly Lys Leu Ser Pro Glu Thr
                645                 650                 655

Gln Ser Ala Ile Glu Gln Glu Ile Arg Ile Leu Leu Arg Asp Ser Tyr
            660                 665                 670

Glu Arg Ala Lys His Ile Leu Lys Thr His Ala Lys Glu His Lys Asn
        675                 680                 685

Leu Ala Glu Ala Leu Leu Thr Tyr Glu Thr Leu Asp Ala Lys Glu Ile
    690                 695                 700

Gln Ile Val Leu Glu Gly Lys Lys Leu Glu Val Arg 
705                 710                 715



<210> 2040
<211> 124
<212> PRT
<213> Homo sapiens

<400> 2040
Met Ala Trp Pro Asn Val Phe Gln Arg Gly Ser Leu Leu Ser Gln Phe
  1               5                  10                  15

Ser His His His Val Val Val Phe Leu Leu Thr Phe Phe Ser Tyr Ser
             20                  25                  30

Leu Leu His Ala Ser Arg Lys Thr Phe Ser Asn Val Lys Val Ser Ile
         35                  40                  45

Ser Glu Gln Trp Thr Pro Ser Ala Phe Asn Thr Ser Val Glu Leu Pro
     50                  55                  60

Leu Glu Ile Trp Ser Ser Asn His Leu Phe Pro Ser Ala Glu Lys Ala
 65                  70                  75                  80

Thr Leu Phe Leu Gly Thr Leu Asp Thr Ile Phe Leu Phe Ser Tyr Ala
                 85                  90                  95

Val Gly Leu Phe Ile Ser Gly Ile Val Gly Asp Arg Leu Asn Leu Arg
            100                 105                 110

Trp Val Leu Ser Phe Gly Met Cys Ser Ser Ala Leu 
        115                 120



<210> 2041
<211> 568
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (240)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (522)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2041
Met Thr Ser Phe Ala Val Leu Met Asp Val Ser Arg Arg Glu Asn Gly
  1               5                  10                  15

Glu Ile Leu Pro Leu Lys Thr Leu Thr Tyr Val Ala Leu Gly Val Ala
             20                  25                  30

Leu Ala Ala Leu Leu Leu Thr Phe Phe Phe Leu Thr Leu Leu Arg Ile
         35                  40                  45

Leu Arg Ser Asn Gln His Gly Ile Arg Arg Asn Leu Thr Ala Ala Leu
     50                  55                  60

Gly Leu Ala Gln Leu Val Phe Leu Leu Gly Ile Asn Gln Ala Asp Leu
 65                  70                  75                  80

Pro Phe Xaa Cys Thr Val Ile Ala Ile Leu Leu His Phe Leu Tyr Leu
                 85                  90                  95

Cys Thr Phe Ser Trp Ala Leu Leu Glu Ala Leu His Leu Tyr Arg Ala
            100                 105                 110

Leu Thr Glu Val Arg Asp Val Asn Thr Gly Pro Met Arg Phe Tyr Tyr
        115                 120                 125

Met Leu Gly Trp Gly Val Pro Ala Phe Ile Thr Gly Leu Ala Val Gly
    130                 135                 140

Leu Asp Pro Glu Gly Tyr Gly Asn Pro Asp Phe Cys Trp Leu Ser Ile
145                 150                 155                 160

Tyr Asp Thr Leu Ile Trp Ser Phe Gly Gly Pro Val Ala Phe Ala Val
                165                 170                 175

Ser Met Ser Val Phe Leu Tyr Ile Leu Ala Ala Arg Ala Ser Cys Ala
            180                 185                 190

Ala Gln Arg Gln Gly Phe Glu Lys Lys Gly Pro Val Ser Gly Leu Gln
        195                 200                 205

Pro Ser Phe Ala Val Leu Leu Leu Leu Ser Ala Thr Trp Leu Leu Ala
    210                 215                 220

Leu Leu Ser Val Asn Arg Asp Thr Leu Leu Phe His Tyr Leu Phe Xaa
225                 230                 235                 240

Thr Cys Asn Cys Ile Gln Gly Pro Phe Ile Phe Leu Ser Tyr Val Val
                245                 250                 255

Leu Ser Lys Glu Val Arg Lys Ala Leu Lys Leu Ala Cys Ser Arg Lys
            260                 265                 270

Pro Ser Pro Asp Pro Ala Leu Thr Thr Lys Ser Thr Leu Thr Ser Ser
        275                 280                 285

Tyr Asn Cys Pro Ser Pro Tyr Ala Asp Gly Arg Leu Tyr Gln Pro Tyr
    290                 295                 300

Gly Asp Ser Ala Gly Ser Leu His Ser Thr Ser Arg Ser Gly Lys Ser
305                 310                 315                 320

Gln Pro Ser Tyr Ile Pro Phe Leu Leu Arg Glu Glu Ser Ala Leu Asn
                325                 330                 335

Pro Gly Gln Gly Pro Pro Gly Leu Gly Asp Pro Gly Ser Leu Phe Leu
            340                 345                 350

Glu Gly Gln Asp Gln Gln His Asp Pro Asp Thr Asp Ser Asp Ser Asp
        355                 360                 365

Leu Ser Leu Glu Asp Asp Gln Ser Gly Ser Tyr Ala Ser Thr His Ser
    370                 375                 380

Ser Asp Ser Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Ala Ala Phe
385                 390                 395                 400

Pro Gly Glu Gln Gly Trp Asp Ser Leu Leu Gly Pro Gly Ala Glu Arg
                405                 410                 415

Leu Pro Leu His Ser Thr Pro Lys Asp Gly Gly Pro Gly Pro Gly Lys
            420                 425                 430

Ala Pro Trp Pro Gly Asp Phe Gly Thr Thr Ala Lys Glu Ser Ser Gly
        435                 440                 445

Asn Gly Ala Pro Glu Glu Arg Leu Arg Glu Asn Gly Asp Ala Leu Ser
    450                 455                 460

Arg Glu Gly Ser Leu Gly Pro Leu Pro Gly Ser Ser Ala Gln Pro His
465                 470                 475                 480

Lys Gly Ile Leu Lys Lys Lys Cys Leu Pro Thr Ile Ser Glu Lys Ser
                485                 490                 495

Ser Leu Leu Arg Leu Pro Leu Glu Gln Cys Thr Gly Ser Ser Arg Gly
            500                 505                 510

Ser Ser Ala Ser Glu Gly Ser Arg Gly Xaa Pro Pro Pro Arg Pro Pro
        515                 520                 525

Pro Arg Gln Ser Leu Gln Glu Gln Leu Asn Gly Val Met Pro Ile Ala
    530                 535                 540

Met Ser Ile Lys Ala Gly Thr Val Asp Glu Asp Ser Ser Gly Ser Glu
545                 550                 555                 560

Phe Leu Phe Phe Asn Phe Leu His 
                565



<210> 2042
<211> 271
<212> PRT
<213> Homo sapiens

<400> 2042
Met Thr Gln Gly Lys Leu Ser Val Ala Asn Lys Ala Pro Gly Thr Glu
  1               5                  10                  15

Gly Gln Gln Gln Val His Gly Glu Lys Lys Glu Ala Pro Ala Val Pro
             20                  25                  30

Ser Ala Pro Pro Ser Tyr Glu Glu Ala Thr Ser Gly Glu Gly Met Lys
         35                  40                  45

Ala Gly Ala Phe Pro Pro Ala Pro Thr Ala Val Pro Leu His Pro Ser
     50                  55                  60

Trp Ala Tyr Val Asp Pro Ser Ser Ser Ser Ser Tyr Asp Asn Gly Phe
 65                  70                  75                  80

Pro Thr Gly Asp His Glu Leu Phe Thr Thr Phe Ser Trp Asp Asp Gln
                 85                  90                  95

Lys Val Arg Arg Val Phe Val Arg Lys Val Tyr Thr Ile Leu Leu Ile
            100                 105                 110

Gln Leu Leu Val Thr Leu Ala Val Val Ala Leu Phe Thr Phe Cys Asp
        115                 120                 125

Pro Val Lys Asp Tyr Val Gln Ala Asn Pro Gly Trp Tyr Trp Ala Ser
    130                 135                 140

Tyr Ala Val Phe Phe Ala Thr Tyr Leu Thr Leu Ala Cys Cys Ser Gly
145                 150                 155                 160

Pro Arg Arg His Phe Pro Trp Glu Pro Asp Ser Pro Asp Arg Leu Tyr
                165                 170                 175

Pro Val His Gly Leu Pro His Trp Asp Ala Val Gln Leu Leu Gln His
            180                 185                 190

His Leu Arg Ala Ala Val Pro Gly His His Gly Pro Cys Leu Pro Leu
        195                 200                 205

Ser His Arg Leu Gln Leu Pro Asp Gln Val Arg Leu His Leu Leu Pro
    210                 215                 220

Gly Arg Ala Leu Arg Ala Ser His Asp Ser Phe Leu Gln Arg Thr His
225                 230                 235                 240

Pro Gly His Pro Pro Thr Leu Pro Ile Cys Ala Leu Ala Pro Cys Ser
                245                 250                 255

Leu Cys Ser Thr Gly Ser Gly Cys Ile Tyr Ile Val Pro Gly Thr 
            260                 265                 270



<210> 2043
<211> 126
<212> PRT
<213> Homo sapiens

<400> 2043
Met Thr Thr Leu Leu Leu Glu Met Ser Thr Pro Phe Thr Cys Val Ser
  1               5                  10                  15

Trp Met Leu Leu Lys Ala Gly Trp Ser Glu Ser Leu Phe Trp Lys Leu
             20                  25                  30

Asn Gln Trp Leu Met Ile His Met Phe His Cys Arg Met Val Leu Thr
         35                  40                  45

Tyr His Met Trp Trp Val Cys Phe Trp His Trp Asp Gly Leu Val Ser
     50                  55                  60

Ser Leu Tyr Leu Pro His Leu Thr Leu Phe Leu Val Gly Leu Ala Leu
 65                  70                  75                  80

Leu Thr Leu Ile Ile Asn Pro Tyr Trp Thr His Lys Lys Thr Gln Gln
                 85                  90                  95

Leu Leu Asn Pro Val Asp Trp Asn Phe Ala Gln Pro Glu Ala Lys Ser
            100                 105                 110

Arg Pro Glu Gly Asn Gly Gln Leu Leu Arg Lys Lys Arg Pro 
        115                 120                 125



<210> 2044
<211> 191
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (162)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2044
Met Ala Ser Ser Ser Ala Ser Ala Thr Pro Glu Phe Glu Gly Arg Gly
  1               5                  10                  15

Gly Asp Asp Leu Gly Thr Glu Ile Ala Asn Thr Leu Tyr Arg Ile Phe
             20                  25                  30

Asn Asn Lys Ser Ser Val Asp Leu Lys Thr Leu Cys Ile Ser Pro Arg
         35                  40                  45

Glu His Cys Xaa Val Leu Tyr Val Asp Val Leu Leu Leu Glu Cys Gly
     50                  55                  60

Gly Asn Leu Phe Asp Ala Ile Ser Ile Ala Val Lys Ala Ala Leu Phe
 65                  70                  75                  80

Asn Thr Arg Xaa Pro Arg Val Arg Val Leu Xaa Xaa Glu Glu Gly Ser
                 85                  90                  95

Lys Xaa Ile Glu Xaa Ser Asp Asp Pro Tyr Asp Cys Ile Arg Leu Xaa
            100                 105                 110

Val Glu Asn Val Pro Cys Ile Val Thr Leu Cys Lys Ile Ala Ile Gly
        115                 120                 125

Met Trp Trp Met Leu Leu Phe Arg Arg Arg Pro Ala Arg Trp Pro Ala
    130                 135                 140

Cys Trp Cys Pro Val Thr Ser Lys Gly Val Ala Thr Cys Met Xaa Lys
145                 150                 155                 160

Val Xaa Lys Gly Xaa Leu Asp Pro Glu Ser Ile Phe Glu Xaa Met Glu
                165                 170                 175

Thr Gly Lys Arg Val Ala Arg Tyr Trp Met Xaa Ser Leu Gln Lys 
            180                 185                 190



<210> 2045
<211> 369
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (357)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (365)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2045
Met Ala Asn Glu Arg Met Asn Leu Met Asn Met Ala Lys Leu Ser Ile
  1               5                  10                  15

Lys Gly Leu Ile Glu Ser Ala Leu Asn Leu Gly Arg Thr Leu Asp Ser
             20                  25                  30

Asp Tyr Ala Pro Leu Gln Gln Phe Phe Val Val Met Glu His Cys Leu
         35                  40                  45

Lys His Gly Leu Lys Ala Lys Lys Thr Phe Leu Gly Gln Asn Lys Ser
     50                  55                  60

Phe Trp Gly Pro Leu Glu Leu Val Glu Lys Leu Val Pro Glu Ala Ala
 65                  70                  75                  80

Glu Ile Thr Ala Ser Val Lys Asp Leu Pro Gly Leu Lys Thr Pro Val
                 85                  90                  95

Gly Arg Gly Arg Ala Trp Leu Arg Leu Ala Leu Met Gln Lys Lys Leu
            100                 105                 110

Ser Glu Tyr Met Lys Ala Leu Ile Asn Lys Lys Glu Leu Leu Ser Glu
        115                 120                 125

Phe Tyr Glu Pro Asn Ala Leu Met Met Glu Glu Glu Gly Ala Ile Ile
    130                 135                 140

Ala Gly Leu Leu Val Gly Leu Asn Val Ile Asp Ala Asn Phe Cys Met
145                 150                 155                 160

Lys Gly Glu Asp Leu Asp Ser Gln Val Gly Val Ile Asp Phe Ser Met
                165                 170                 175

Tyr Leu Lys Asp Gly Asn Ser Ser Lys Gly Thr Glu Gly Asp Gly Gln
            180                 185                 190

Ile Thr Ala Ile Leu Asp Gln Lys Asn Tyr Val Glu Glu Leu Asn Arg
        195                 200                 205

His Leu Asn Ala Thr Val Asn Asn Leu Gln Ala Lys Val Asp Ala Leu
    210                 215                 220

Glu Lys Ser Asn Thr Lys Leu Thr Glu Glu Leu Ala Val Ala Asn Asn
225                 230                 235                 240

Arg Ile Ile Thr Leu Gln Glu Glu Met Glu Arg Val Lys Glu Glu Ser
                245                 250                 255

Ser Tyr Ile Leu Glu Ser Asn Arg Lys Gly Pro Lys Gln Asp Arg Thr
            260                 265                 270

Ala Glu Gly Gln Ala Leu Ser Glu Ala Arg Lys His Leu Lys Glu Glu
        275                 280                 285

Thr Gln Leu Arg Leu Asp Val Glu Lys Glu Leu Glu Met Gln Ile Ser
    290                 295                 300

Met Arg Gln Glu Met Glu Leu Ala Met Lys Met Leu Glu Lys Asp Val
305                 310                 315                 320

Cys Glu Lys Gln Val Pro Trp Tyr Leu Phe Gly Gln Gln Leu Asp Asp
                325                 330                 335

Leu Arg Ala Leu Lys His Glu Leu Ala Phe Lys Leu Gln Ser Ser Asp
            340                 345                 350

Leu Gly Val Lys Xaa Lys Ser Glu Leu Asn Ser Arg Xaa Gly Arg Glu
        355                 360                 365

Asp 




<210> 2046
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2046
Met Thr His Leu Leu Pro Arg Leu Pro Gln His Met Phe Tyr Val Gly
  1               5                  10                  15

Gln Asp Ser Ser Arg Cys Val Xaa Cys Met Val Asp Ser Ser Leu Gly
             20                  25                  30

Val Trp Val Thr Leu Lys Gly Ser Ala His Val Cys Leu Tyr His Pro
         35                  40                  45

Asp Thr Phe Glu Gln Leu Ala Glu Val Asp Val Thr Pro Pro Val His
     50                  55                  60

Arg Met Leu Ala Gly Ser Asp Ala Ile Ile Arg Gln His Lys Ala Ala
 65                  70                  75                  80

Cys Leu Arg Ile Thr Ala Leu Leu Val Cys Glu Glu Leu Leu Trp Val
                 85                  90                  95

Gly Thr Xaa Ala Gly Val Val Ser Pro Cys Pro Leu Arg Pro Xaa Leu
            100                 105                 110






<210> 2047
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2047
Met Gly Pro Ser Pro Gln Ile Gln Ser Ser Gln Ala Phe His Glu Leu
  1               5                  10                  15

Ala Ser Ser Phe Cys Ser Leu Ser Asn Cys Pro Gly Cys Pro Val Ser
             20                  25                  30

Asp Ser Ser Tyr Phe Val Gly Leu Leu Trp Asn His Glu Lys Ser Pro
         35                  40                  45

Lys Gln Ser Gln Phe Ser Ser Ser Leu Arg Leu Asp Ile Ser Thr Leu
     50                  55                  60

Ser Ser Leu Val Phe Leu Glu Ile Asn Leu Leu Phe Phe Ile Val Phe
 65                  70                  75                  80

Leu Trp Ser Cys Phe Pro Phe Val Gly Tyr Tyr Phe Ile Phe Ser Phe
                 85                  90                  95

Ser His His Thr Asp Ile Cys Trp Leu Phe Phe 
            100                 105



<210> 2048
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2048
Met Cys Met Val Ile Phe Ala Pro Leu Phe Ala Ile Phe Ala Phe Ala
  1               5                  10                  15

Thr Cys Gly Gly Tyr Ser Gly Gly Leu Arg Leu Ser Val Asp Cys Val
             20                  25                  30

Asn Lys Thr Glu Ser Asn Leu Ser Ile Asp Ile Ala Phe Ala Tyr Pro
         35                  40                  45

Phe Arg Leu His Gln Val Thr Phe Glu Val Pro Thr Cys Glu Gly Lys
     50                  55                  60

Glu Arg Gln Lys Leu Ala Leu Ile Gly Asp Ser Ser Ser Ser Ala Glu
 65                  70                  75                  80

Phe Phe Val Thr Val Ala Val Phe Ala Phe Leu Tyr Ser Leu Ala Ala
                 85                  90                  95

Thr Val Val Tyr Ile Phe Phe Gln Asn Lys Tyr Arg Glu Asn Asn Arg
            100                 105                 110

Gly Pro Leu Ile Asp Phe Ile Val Thr Val Val Phe Ser Phe Leu Trp
        115                 120                 125

Leu Val Gly Ser Ser Ala Trp Ala Lys Gly Leu Ser Asp Val Lys Val
    130                 135                 140

Ala Thr Asp Pro Lys Glu Val Leu Leu Leu Met Ser Ala Xaa Lys Gln
145                 150                 155                 160

Ala Ile Gln Gln Met His Gly Leu Ser Thr Ala Leu Leu Cys Gln Ala
                165                 170                 175






<210> 2049
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2049
Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu
  1               5                  10                  15

Pro Gly Gln Thr Pro Glu Ala Ala Lys Glu Ala Glu Leu Ala Ala Arg
             20                  25                  30

Ile Leu Leu Asp Gln Gly Gln Thr His Ser Val Glu Thr Pro Tyr Gly
         35                  40                  45

Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg Pro Ala
     50                  55                  60

Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys Phe Gln
 65                  70                  75                  80

Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn Phe Val
                 85                  90                  95

Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro Val Phe
            100                 105                 110

Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp Met Ile
        115                 120                 125

Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly Val Gly
    130                 135                 140

Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn His Xaa
145                 150                 155                 160

Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn Ala Lys
                165                 170                 175

Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr Ser Ser
            180                 185                 190

Ile Pro Glu Met Ile Leu Gly His Leu Phe 
        195                 200



<210> 2050
<211> 325
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (285)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2050
Met Ala Glu Leu Gln Glu Val Gln Ile Thr Glu Glu Lys Pro Leu Leu
  1               5                  10                  15

Pro Gly Gln Thr Pro Glu Ala Ala Lys Thr His Ser Val Glu Thr Pro
             20                  25                  30

Tyr Gly Ser Val Thr Phe Thr Val Tyr Gly Thr Pro Lys Pro Lys Arg
         35                  40                  45

Pro Ala Ile Leu Thr Tyr His Asp Val Gly Leu Asn Tyr Lys Ser Cys
     50                  55                  60

Phe Gln Pro Leu Phe Gln Phe Glu Asp Met Gln Glu Ile Ile Gln Asn
 65                  70                  75                  80

Phe Val Arg Val His Val Asp Ala Pro Gly Met Glu Glu Gly Ala Pro
                 85                  90                  95

Val Phe Pro Leu Gly Tyr Gln Tyr Pro Ser Leu Asp Gln Leu Ala Asp
            100                 105                 110

Met Ile Pro Cys Val Leu Gln Tyr Leu Asn Phe Ser Thr Ile Ile Gly
        115                 120                 125

Val Gly Val Gly Ala Gly Ala Tyr Ile Leu Ala Arg Tyr Ala Leu Asn
    130                 135                 140

His Pro Asp Thr Val Glu Gly Leu Val Leu Ile Asn Ile Asp Pro Asn
145                 150                 155                 160

Ala Lys Gly Trp Met Asp Trp Ala Ala His Lys Leu Thr Gly Leu Thr
                165                 170                 175

Ser Ser Ile Pro Glu Met Ile Leu Gly His Leu Phe Ser Gln Glu Glu
            180                 185                 190

Leu Ser Gly Asn Ser Glu Leu Ile Gln Lys Tyr Arg Asn Ile Ile Thr
        195                 200                 205

His Ala Pro Asn Leu Asp Asn Ile Glu Leu Tyr Trp Asn Ser Tyr Asn
    210                 215                 220

Asn Arg Arg Asp Leu Asn Phe Glu Arg Gly Gly Asp Ile Thr Leu Arg
225                 230                 235                 240

Cys Pro Val Met Leu Val Val Gly Asp Gln Ala Pro His Glu Asp Ala
                245                 250                 255

Val Val Glu Cys Asn Ser Lys Leu Asp Pro Thr Gln Thr Ser Phe Leu
            260                 265                 270

Lys Met Ala Asp Ser Gly Gly Gln Pro Gln Leu Thr Xaa Ala Arg Gln
        275                 280                 285

Ala Asp Arg Gly Leu Gln Val Leu Pro Ala Arg His Gly Leu His Gly
    290                 295                 300

Leu Ile Leu His Asp Ser Pro Val Pro Val Ser Tyr Ser Leu Ser Asp
305                 310                 315                 320

Gln Cys Ser Ile Arg 
                325



<210> 2051
<211> 105
<212> PRT
<213> Homo sapiens

<400> 2051
Met Phe Ser Thr Gln Thr Gly Pro Ala Phe Leu Gly Cys Gly Leu Arg
  1               5                  10                  15

Ala Arg Thr Asp Pro Thr Ala Ser Pro Ser Ser Ser Ser Val Cys His
             20                  25                  30

Arg Asn Val Arg Gly Val Phe Ala Glu Arg Ser Gly His Gly Gln Arg
         35                  40                  45

Ala Ser Glu His Ala Arg Thr Ser Ser Pro Cys Pro Val Ser His Pro
     50                  55                  60

Ala Pro Gly Glu Ile Gly Ala Thr Lys Glu Glu Ser Thr Gln Ile Arg
 65                  70                  75                  80

Gln Arg Gly Gly Gly Gly His Phe Leu His Ser Ser Leu Phe Ala Ala
                 85                  90                  95

Ala Glu Ile Ala Val Phe Ile Ala Met 
            100                 105



<210> 2052
<211> 290
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2052
Met Glu Arg Gly Pro Val Val Gly Ala Gly Leu Gly Ala Gly Arg Asn
  1               5                  10                  15

Pro Gly Thr Ala Gly Leu Pro Ala Gln Gly Ala Ala Leu Gly Gly Leu
             20                  25                  30

Cys Leu Leu Tyr Phe Gly Xaa Glu Gln Ala Ala Arg Leu Leu Gly Ser
         35                  40                  45

Pro Cys Leu Arg Arg Leu Tyr His Ala Trp Leu Ala Ala Val Val Ile
     50                  55                  60

Phe Gly Pro Leu Leu Gln Phe His Val Asn Pro Arg Thr Ile Phe Ala
 65                  70                  75                  80

Ser His Gly Asn Phe Phe Asn Ile Lys Phe Val Asn Ser Ala Trp Gly
                 85                  90                  95

Trp Thr Cys Thr Phe Leu Gly Gly Phe Val Leu Leu Val Val Phe Leu
            100                 105                 110

Ala Thr Arg Arg Val Ala Val Thr Ala Arg His Leu Xaa Arg Leu Val
        115                 120                 125

Val Gly Ala Xaa Val Trp Arg Gly Xaa Gly Arg Ala Phe Leu Leu Ile
    130                 135                 140

Glu Asp Leu Thr Gly Ser Cys Phe Glu Pro Leu Pro Gln Gly Leu Leu
145                 150                 155                 160

Leu His Glu Leu Pro Asp Arg Arg Ser Cys Leu Ala Ala Gly His Gln
                165                 170                 175

Trp Arg Gly Tyr Thr Val Ser Ser His Thr Phe Leu Leu Thr Phe Cys
            180                 185                 190

Cys Leu Leu Met Ala Glu Glu Ala Ala Val Phe Ala Lys Tyr Leu Arg
        195                 200                 205

Pro Trp Ala Ser Cys Arg Arg Pro Thr Ala Pro Cys Leu Pro Ala Glu
    210                 215                 220

Arg Ala Ala Ala Gly Pro Leu Glu Leu Leu Ala Ala Leu Tyr Arg His
225                 230                 235                 240

Leu Phe Pro Pro Val His Ser Gln Gly Gly Gly Arg Arg Ser Gly His
                245                 250                 255

Leu Cys Leu Val Pro His Leu Trp Gln Leu Val Ser Ser Ala Leu Val
            260                 265                 270

Ser Arg Glu Pro Arg Pro Trp Ala Leu Pro Pro Ser Pro Leu Gln Pro
        275                 280                 285

Gln Ala 
    290



<210> 2053
<211> 162
<212> PRT
<213> Homo sapiens

<400> 2053
Met Asp Cys Phe Ile Phe Ser Gln Glu Glu Ser Leu Ser Ile Ser Cys
  1               5                  10                  15

Ala Ala His Ser Trp Lys Trp Leu Gln Thr Asn Gln Cys Arg Lys Leu
             20                  25                  30

Lys Trp Gly Cys Phe Pro Leu Cys Val Val Val Lys Gly Arg Val Thr
         35                  40                  45

Gln Tyr Leu Trp Ile Phe Arg Asp Ser Val Phe Leu Arg Cys Leu Ser
     50                  55                  60

Asn Gly Ser Ser His Leu Tyr Tyr Phe Gln Ile Ile Arg Lys Thr Val
 65                  70                  75                  80

Phe Asn Ser Ser Phe Pro Phe Ile Ala Leu Arg Val Val Val Thr Asp
                 85                  90                  95

Phe Ser Phe Glu Asn Arg Leu His Gln His Pro Arg Leu Pro Thr Pro
            100                 105                 110

Pro Pro Phe Tyr Leu Val Cys Leu Phe Phe Val Cys Leu Leu Pro Ser
        115                 120                 125

Ser His Val Leu Phe Pro Leu Arg Ala Val Asn Gly Gln Val Cys Leu
    130                 135                 140

Trp Phe Gly Ile Thr Glu Phe Phe Pro Cys Ile Gly Pro Arg Ala Ala
145                 150                 155                 160

Arg Met 




<210> 2054
<211> 105
<212> PRT
<213> Homo sapiens

<400> 2054
Met Gly Asn Leu Arg Gly Lys Arg Gln Gly Pro Ala Cys Pro Ala Met
  1               5                  10                  15

Arg Gly Ile Pro Cys Pro Pro Ala Leu Cys Leu Pro Arg Trp Asn Val
             20                  25                  30

Gly Pro Cys Ser Pro Ser Gly Cys Ala Val Ser Asp Leu Cys Leu His
         35                  40                  45

Pro Arg Gly Val Ser Ala Ser Ser Pro Pro Arg Ser Gly Cys Gly Pro
     50                  55                  60

Ala Ala Cys Cys Gly Val Leu Thr Cys Val Thr Thr Ala Pro Leu Ala
 65                  70                  75                  80

Pro Gly Gly Val Met Val Ser Ser Trp Met Leu Leu Leu Glu Ser Phe
                 85                  90                  95

Phe Leu Ile Asn Leu Leu Gln Leu Arg 
            100                 105



<210> 2055
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2055
Met Cys Leu Pro Pro Leu Cys Gly His Gly Phe Ala Xaa Ala Ser Lys
  1               5                  10                  15

Cys Arg Arg Thr Cys His Leu Arg Leu Val Leu His Ser Gly Pro Trp
             20                  25                  30

Leu Arg Phe Leu Leu Val Cys Leu Pro Arg Ser Ser Phe Leu Tyr Pro
         35                  40                  45

Cys Asp Gln Thr Val Phe Val Gly Thr Val Ala Asp Leu Gly Phe Leu
     50                  55                  60

Gln Phe Phe Leu Ser Lys Leu His Pro Val Pro Gln Glu Arg Gly Glu
 65                  70                  75                  80

Asn Ser Pro Asn Val Phe Gly Phe Leu Ala Ala Trp Asn Leu Leu Leu
                 85                  90                  95

Pro Pro Ala Gly His His Cys Pro His 
            100                 105



<210> 2056
<211> 216
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (148)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (171)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2056
Met Phe Tyr Phe Arg Gly Cys Gly Arg Trp Val Ala Val Ser Phe Thr
  1               5                  10                  15

Lys Gln Gln Phe Pro Leu Ala Arg Leu Ser Ser Asp Ser Ala Ala Pro
             20                  25                  30

Arg Thr Pro His Phe Asp Val Ile Val Ile Gly Gly Gly His Ala Gly
         35                  40                  45

Thr Glu Ala Ala Thr Ala Ala Ala Arg Cys Gly Ser Arg Thr Leu Leu
     50                  55                  60

Leu Thr His Arg Val Asp Thr Ile Gly Gln Met Ser Cys Asn Pro Ser
 65                  70                  75                  80

Phe Gly Gly Ile Gly Lys Gly His Leu Met Arg Glu Val Asp Ala Leu
                 85                  90                  95

Asp Gly Leu Cys Ser Arg Ile Cys Asp Gln Ser Gly Val His Tyr Lys
            100                 105                 110

Val Leu Asn Arg Arg Lys Gly Pro Ala Val Trp Gly Leu Xaa Ala Gln
        115                 120                 125

Ile Asp Arg Lys Leu Tyr Lys Gln Asn Met Gln Lys Glu Ile Leu Asn
    130                 135                 140

Thr Pro Leu Xaa Thr Val Gln Glu Gly Xaa Val Glu Asp Leu Ile Leu
145                 150                 155                 160

Thr Glu Pro Glu Pro Glu His Thr Gly Lys Xaa Arg Val Ser Gly Val
                165                 170                 175

Val Leu Val Asp Gly Ser Thr Val Tyr Ala Glu Ser Val Ile Leu Thr
            180                 185                 190

Thr Gly Thr Phe Leu Arg Gly Met Ile Val Ile Gly Leu Glu Thr His
        195                 200                 205

Pro Ala Gly Arg Leu Gly Asp Gln 
    210                 215



<210> 2057
<211> 316
<212> PRT
<213> Homo sapiens

<400> 2057
Met Phe Ser Ser Pro Ser Pro Pro Pro Ala Leu Leu Glu Lys Val Phe
  1               5                  10                  15

Gln Tyr Ile Asp Leu His Gln Asp Glu Phe Val Gln Thr Leu Lys Glu
             20                  25                  30

Trp Val Ala Ile Glu Ser Asp Ser Val Gln Pro Val Pro Arg Phe Arg
         35                  40                  45

Gln Glu Leu Phe Arg Met Met Ala Val Ala Ala Asp Thr Leu Gln Arg
     50                  55                  60

Leu Gly Ala Arg Val Ala Ser Val Asp Met Gly Pro Gln Gln Val Leu
 65                  70                  75                  80

Asp Gly Gln Ser Leu Pro Ile Pro Pro Val Ile Leu Ala Glu Leu Gly
                 85                  90                  95

Ser Asp Pro Thr Lys Gly Thr Val Cys Phe Tyr Gly His Leu Asp Val
            100                 105                 110

Gln Pro Ala Asp Arg Gly Asp Gly Trp Leu Thr Asp Pro Tyr Val Leu
        115                 120                 125

Thr Glu Val Asp Gly Lys Leu Tyr Gly Arg Gly Ala Thr Asp Asn Lys
    130                 135                 140

Gly Pro Val Leu Ala Trp Ile Asn Ala Val Ser Ala Phe Arg Ala Leu
145                 150                 155                 160

Glu Gln Asp Leu Pro Val Asn Ile Lys Phe Ile Ile Glu Gly Met Glu
                165                 170                 175

Arg Gly Trp Leu Cys Leu Pro Trp Arg Asn Leu Trp Glu Lys Glu Lys
            180                 185                 190

Asp Arg Phe Phe Ser Gly Val Asp Tyr Ile Val Ile Ser Asp Asn Leu
        195                 200                 205

Trp Ile Ser Gln Arg Lys Pro Ala Ile Thr Tyr Gly Thr Arg Gly Asn
    210                 215                 220

Ser Tyr Phe Met Val Glu Val Lys Cys Arg Asp Gln Asp Phe His Ser
225                 230                 235                 240

Gly Thr Phe Gly Gly Ile Leu His Glu Pro Met Ala Asp Leu Val Ala
                245                 250                 255

Leu Leu Gly Ser Leu Val Asp Ser Ser Gly His Ile Leu Val Pro Gly
            260                 265                 270

Ile Tyr Asp Glu Val Val Pro Leu Thr Glu Glu Glu Ile Asn Thr Tyr
        275                 280                 285

Gln Ser His Pro Ser Arg Pro Lys Lys Asn Thr Gly Ile Ala Ala Gly
    290                 295                 300

Leu Arg Asn Phe Cys Ser Ile Leu Arg Arg Arg Phe 
305                 310                 315



<210> 2058
<211> 262
<212> PRT
<213> Homo sapiens

<400> 2058
Met Leu Phe Ser Ala Leu Leu Leu Glu Val Ile Trp Ile Leu Ala Ala
  1               5                  10                  15

Asp Gly Gly Gln His Trp Thr Tyr Glu Gly Pro His Gly Gln Asp His
             20                  25                  30

Trp Pro Ala Ser Tyr Pro Glu Cys Gly Asn Asn Ala Gln Ser Pro Ile
         35                  40                  45

Asp Ile Gln Thr Asp Ser Val Thr Phe Asp Pro Asp Leu Pro Ala Leu
     50                  55                  60

Gln Pro His Gly Tyr Asp Gln Pro Gly Thr Glu Pro Leu Asp Leu His
 65                  70                  75                  80

Asn Asn Gly His Thr Val Gln Leu Ser Leu Pro Ser Thr Leu Tyr Leu
                 85                  90                  95

Gly Gly Leu Pro Arg Lys Tyr Val Ala Ala Gln Leu His Leu His Trp
            100                 105                 110

Gly Gln Lys Gly Ser Pro Gly Gly Ser Glu His Gln Ile Asn Ser Glu
        115                 120                 125

Ala Thr Phe Ala Glu Leu His Ile Val His Tyr Asp Ser Asp Ser Tyr
    130                 135                 140

Asp Ser Leu Ser Glu Ala Ala Glu Arg Pro Gln Gly Leu Ala Val Leu
145                 150                 155                 160

Gly Ile Leu Ile Glu Leu Glu Lys Leu Gln Gly Thr Leu Phe Ser Thr
                165                 170                 175

Glu Glu Glu Pro Ser Lys Leu Leu Val Gln Asn Tyr Arg Ala Leu Gln
            180                 185                 190

Pro Leu Asn Gln Arg Met Val Phe Ala Ser Phe Ile Gln Ala Gly Ser
        195                 200                 205

Ser Tyr Thr Thr Gly Glu Met Leu Ser Leu Gly Val Gly Ile Leu Val
    210                 215                 220

Gly Cys Leu Cys Leu Leu Leu Ala Val Tyr Phe Ile Ala Arg Lys Ile
225                 230                 235                 240

Arg Lys Lys Arg Leu Glu Asn Arg Lys Ser Val Val Phe Thr Ser Ala
                245                 250                 255

Gln Ala Thr Thr Glu Ala 
            260



<210> 2059
<211> 438
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2059
Met Pro Glu Gly Gly Gly Ala Leu Ala Glu Gly Phe Gln Val Arg Met
  1               5                  10                  15

Phe Glu Phe Gln Asn Phe Glu Arg Arg Phe Glu Glu Cys Ile Ser Gln
             20                  25                  30

Ser Ala Val Lys Thr Lys Phe Glu Gln His Thr Val Arg Ala Lys Gln
         35                  40                  45

Ile Ala Glu Ala Val Arg Leu Ile Met Asp Ser Leu His Met Ala Ala
     50                  55                  60

Arg Glu Gln Gln Val Tyr Cys Xaa Glu Met Arg Glu Glu Arg Gln Asp
 65                  70                  75                  80

Arg Leu Lys Phe Ile Asp Lys Gln Leu Glu Leu Leu Ala Gln Asp Tyr
                 85                  90                  95

Lys Leu Arg Ile Lys Gln Ile Thr Glu Glu Val Glu Arg Gln Val Ser
            100                 105                 110

Thr Ala Met Ala Glu Glu Ile Arg Arg Leu Ser Val Leu Val Asp Asp
        115                 120                 125

Tyr Gln Met Asp Phe His Pro Ser Pro Val Val Leu Lys Val Tyr Lys
    130                 135                 140

Asn Glu Leu His Arg His Ile Glu Glu Gly Leu Gly Arg Asn Met Ser
145                 150                 155                 160

Asp Arg Cys Ser Thr Ala Ile Thr Asn Ser Leu Gln Thr Met Gln Gln
                165                 170                 175

Asp Met Ile Asp Gly Leu Lys Pro Leu Leu Pro Val Ser Val Arg Ser
            180                 185                 190

Gln Ile Asp Met Leu Val Pro Arg Gln Cys Phe Ser Leu Asn Tyr Asp
        195                 200                 205

Leu Asn Cys Asp Lys Leu Cys Ala Asp Phe Gln Glu Asp Ile Glu Phe
    210                 215                 220

His Phe Ser Leu Gly Trp Thr Met Leu Val Asn Arg Phe Leu Gly Pro
225                 230                 235                 240

Lys Asn Ser Arg Arg Ala Leu Met Gly Tyr Asn Asp Gln Val Gln Arg
                245                 250                 255

Pro Ile Pro Leu Thr Pro Ala Asn Pro Ser Met Pro Pro Leu Pro Gln
            260                 265                 270

Gly Ser Leu Thr Gln Glu Glu Phe Met Val Ser Met Val Thr Gly Leu
        275                 280                 285

Ala Ser Leu Thr Ser Arg Thr Ser Met Gly Ile Leu Val Val Gly Gly
    290                 295                 300

Val Val Trp Lys Ala Val Gly Trp Arg Leu Ile Ala Leu Ser Phe Gly
305                 310                 315                 320

Leu Tyr Gly Leu Leu Tyr Val Tyr Glu Arg Leu Thr Trp Thr Thr Lys
                325                 330                 335

Ala Lys Glu Arg Ala Phe Lys Arg Gln Phe Val Glu His Ala Ser Glu
            340                 345                 350

Lys Leu Gln Leu Val Ile Ser Tyr Thr Gly Ser Asn Cys Ser His Gln
        355                 360                 365

Val Gln Gln Glu Leu Ser Gly Thr Phe Ala His Leu Cys Gln Gln Val
    370                 375                 380

Asp Val Thr Arg Glu Asn Leu Glu Gln Glu Ile Ala Ala Met Asn Lys
385                 390                 395                 400

Lys Ile Glu Val Leu Asp Ser Leu Gln Ser Lys Ala Lys Leu Leu Arg
                405                 410                 415

Asn Lys Ala Gly Trp Leu Asp Ser Glu Leu Asn Met Phe Thr His Gln
            420                 425                 430

Tyr Leu Gln Pro Ser Arg 
        435



<210> 2060
<211> 160
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (147)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2060
Met Ala Trp Arg Gly Trp Ala Gln Arg Gly Trp Gly Cys Gly Gln Ala
  1               5                  10                  15

Trp Gly Ala Ser Val Gly Gly Arg Ser Cys Glu Glu Leu Thr Ala Val
             20                  25                  30

Leu Thr Pro Pro Gln Leu Leu Gly Arg Arg Phe Asn Phe Phe Ile Gln
         35                  40                  45

Gln Lys Cys Gly Phe Arg Lys Ala Pro Arg Lys Val Glu Pro Arg Arg
     50                  55                  60

Ser Asp Pro Gly Thr Ser Gly Glu Ala Tyr Lys Arg Ser Ala Leu Ile
 65                  70                  75                  80

Pro Pro Val Glu Glu Thr Val Phe Tyr Pro Ser Pro Tyr Pro Ile Arg
                 85                  90                  95

Ser Leu Ile Lys Pro Leu Phe Phe Thr Val Gly Phe Thr Gly Cys Ala
            100                 105                 110

Phe Gly Ser Ala Ala Ile Trp Gln Tyr Glu Ser Leu Lys Ser Arg Val
        115                 120                 125

Gln Ser Tyr Phe Asp Gly Ile Lys Ala Asp Trp Leu Asp Ser Ile Arg
    130                 135                 140

Pro Gln Xaa Glu Gly Asp Phe Arg Lys Glu Ile Asn Lys Trp Trp Xaa
145                 150                 155                 160






<210> 2061
<211> 261
<212> PRT
<213> Homo sapiens

<400> 2061
Met Glu Leu Leu Gln Val Thr Ile Leu Phe Leu Leu Pro Ser Ile Cys
  1               5                  10                  15

Ser Ser Asn Ser Thr Gly Val Leu Glu Ala Ala Asn Asn Ser Leu Val
             20                  25                  30

Val Thr Thr Thr Lys Pro Ser Ile Thr Thr Pro Asn Thr Glu Ser Leu
         35                  40                  45

Gln Lys Asn Val Val Thr Pro Thr Thr Gly Thr Thr Pro Lys Gly Thr
     50                  55                  60

Ile Thr Asn Glu Leu Leu Lys Met Ser Leu Met Ser Thr Ala Thr Phe
 65                  70                  75                  80

Leu Thr Ser Lys Asp Glu Gly Leu Lys Ala Thr Thr Thr Asp Val Arg
                 85                  90                  95

Lys Asn Asp Ser Ile Ile Ser Asn Val Thr Val Thr Ser Val Thr Leu
            100                 105                 110

Pro Asn Ala Val Ser Thr Leu Gln Ser Ser Lys Pro Lys Thr Glu Thr
        115                 120                 125

Gln Ser Ser Ile Lys Thr Thr Glu Ile Pro Gly Ser Val Leu Gln Pro
    130                 135                 140

Asp Ala Ser Pro Ser Lys Thr Gly Thr Leu Thr Ser Ile Pro Val Thr
145                 150                 155                 160

Ile Pro Glu Asn Thr Ser Gln Ser Gln Val Ile Gly Thr Glu Gly Gly
                165                 170                 175

Lys Asn Ala Ser Thr Ser Ala Thr Ser Arg Ser Tyr Ser Ser Ile Ile
            180                 185                 190

Leu Pro Val Val Ile Ala Leu Ile Val Ile Thr Leu Ser Val Phe Val
        195                 200                 205

Leu Val Gly Leu Tyr Arg Met Cys Trp Lys Ala Asp Pro Gly Thr Pro
    210                 215                 220

Glu Asn Gly Asn Asp Gln Pro Gln Ser Asp Lys Glu Ser Val Lys Leu
225                 230                 235                 240

Leu Thr Val Lys Thr Ile Ser His Glu Ser Gly Glu His Ser Ala Gln
                245                 250                 255

Gly Lys Thr Lys Asn 
            260



<210> 2062
<211> 504
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (194)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (403)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2062
Met Gly Ile Lys Thr Ala Leu Pro Ala Ala Glu Leu Gly Leu Tyr Ser
  1               5                  10                  15

Leu Val Leu Ser Gly Ala Leu Ala Tyr Ala Gly Arg Gly Leu Leu Glu
             20                  25                  30

Ala Ser Gln Asp Gly Ala His Arg Lys Ala Phe Arg Glu Ser Val Arg
         35                  40                  45

Pro Gly Trp Glu Tyr Ile Gly Arg Lys Met Asp Val Ala Asp Phe Glu
     50                  55                  60

Trp Val Met Trp Phe Thr Ser Phe Arg Asn Val Ile Ile Phe Ala Leu
 65                  70                  75                  80

Ser Gly His Val Leu Phe Ala Lys Leu Cys Thr Met Val Ala Pro Lys
                 85                  90                  95

Leu Arg Xaa Trp Met Tyr Ala Val Tyr Gly Ala Leu Ala Val Met Gly
            100                 105                 110

Thr Met Gly Pro Trp Tyr Leu Leu Leu Leu Leu Gly His Cys Val Gly
        115                 120                 125

Leu Tyr Val Ala Ser Leu Leu Gly Gln Pro Trp Leu Cys Leu Gly Leu
    130                 135                 140

Gly Leu Ala Ser Leu Ala Ser Phe Lys Met Asp Pro Leu Ile Ser Trp
145                 150                 155                 160

Gln Ser Gly Phe Val Thr Gly Thr Phe Asp Leu Gln Glu Val Leu Phe
                165                 170                 175

His Gly Gly Ser Ser Phe Thr Val Leu Arg Cys Thr Xaa Phe Ala Leu
            180                 185                 190

Glu Xaa Cys Ala His Pro Asp Arg His Tyr Ser Leu Ala Asp Leu Leu
        195                 200                 205

Lys Tyr Asn Phe Tyr Leu Pro Phe Phe Phe Phe Gly Pro Ile Met Thr
    210                 215                 220

Phe Asp Arg Phe His Ala Gln Val Ser Gln Val Glu Pro Val Arg Arg
225                 230                 235                 240

Glu Gly Glu Leu Trp His Ile Arg Ala Gln Ala Gly Leu Ser Val Val
                245                 250                 255

Ala Ile Met Ala Val Asp Ile Phe Phe His Phe Phe Tyr Ile Leu Thr
            260                 265                 270

Ile Pro Ser Asp Leu Lys Phe Ala Asn Arg Leu Pro Asp Ser Ala Leu
        275                 280                 285

Ala Gly Leu Ala Tyr Ser Asn Leu Val Tyr Asp Trp Val Lys Ala Ala
    290                 295                 300

Val Leu Phe Gly Val Val Asn Thr Val Ala Cys Leu Asp His Leu Asp
305                 310                 315                 320

Pro Pro Gln Pro Pro Lys Cys Ile Thr Ala Leu Tyr Val Phe Ala Glu
                325                 330                 335

Thr His Phe Asp Arg Gly Ile Asn Asp Trp Leu Cys Lys Tyr Val Tyr
            340                 345                 350

Asn His Ile Gly Gly Glu His Ser Ala Val Ile Pro Glu Leu Ala Ala
        355                 360                 365

Thr Val Ala Thr Phe Ala Ile Thr Thr Leu Trp Leu Gly Pro Cys Asp
    370                 375                 380

Ile Val Tyr Leu Trp Ser Phe Leu Asn Cys Phe Gly Leu Asn Phe Glu
385                 390                 395                 400

Leu Trp Xaa Gln Lys Leu Ala Glu Trp Gly Pro Leu Ala Arg Ile Glu
                405                 410                 415

Ala Ser Leu Ser Val Gln Met Ser Arg Arg Val Arg Ala Leu Phe Gly
            420                 425                 430

Ala Met Asn Phe Trp Ala Ile Ile Met Tyr Asn Leu Val Ser Leu Asn
        435                 440                 445

Ser Leu Lys Phe Thr Glu Leu Val Ala Arg Arg Leu Leu Leu Thr Gly
    450                 455                 460

Phe Pro Gln Thr Thr Leu Ser Ile Leu Phe Val Thr Tyr Cys Gly Val
465                 470                 475                 480

Gln Leu Val Lys Glu Arg Glu Arg Thr Leu Ala Leu Glu Glu Glu Gln
                485                 490                 495

Lys Gln Asp Lys Glu Lys Pro Glu 
            500



<210> 2063
<211> 259
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (242)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2063
Met Leu Ser Lys Gly Ala Leu Asn Pro Ala Asp Ile Thr Val Leu Phe
  1               5                  10                  15

Lys Met Phe Thr Ser Met Asp Pro Pro Pro Val Glu Leu Ile Arg Val
             20                  25                  30

Pro Ala Phe Leu Asp Leu Phe Met Gln Ser Leu Phe Lys Pro Gly Ala
         35                  40                  45

Arg Ile Asn Gln Asp His Lys His Lys Tyr Ile His Ile Leu Ala Tyr
     50                  55                  60

Ala Ala Ser Val Val Glu Thr Trp Lys Lys Asn Lys Arg Val Ser Ile
 65                  70                  75                  80

Asn Lys Asp Glu Leu Lys Ser Thr Ser Lys Ala Val Glu Thr Val His
                 85                  90                  95

Asn Leu Cys Cys Asn Glu Asn Lys Gly Ala Ser Glu Leu Val Ala Glu
            100                 105                 110

Leu Ser Thr Leu Tyr Gln Cys Ile Arg Phe Pro Val Val Ala Met Gly
        115                 120                 125

Val Leu Lys Trp Val Asp Trp Thr Val Ser Glu Pro Arg Tyr Phe Gln
    130                 135                 140

Leu Gln Thr Asp His Thr Pro Val His Leu Ala Leu Leu Asp Glu Ile
145                 150                 155                 160

Ser Thr Cys His Gln Leu Leu His Pro Gln Val Leu Gln Leu Leu Val
                165                 170                 175

Lys Leu Phe Glu Thr Glu His Ser Gln Leu Asp Val Met Glu Gln Leu
            180                 185                 190

Glu Leu Lys Lys Thr Leu Leu Asp Arg Met Val His Leu Leu Ser Arg
        195                 200                 205

Gly Tyr Val Leu Pro Val Val Ser Tyr Ile Arg Lys Cys Leu Glu Lys
    210                 215                 220

Leu Asp Thr Asp Ile Ser Leu Ile Arg Tyr Phe Val Thr Glu Val Ser
225                 230                 235                 240

Asn Xaa Pro Leu Val Ser Cys Phe Ile Leu Phe Thr Leu Ala Leu Pro
                245                 250                 255

Phe Leu Ala 




<210> 2064
<211> 177
<212> PRT
<213> Homo sapiens

<400> 2064
Met Gln Thr Thr Gln Val Ile Glu Pro His Asp Ile Ser Val Ala Leu
  1               5                  10                  15

Asn Thr Arg Lys Leu Trp Ser Met His Leu His Val Gln Ala Lys Leu
             20                  25                  30

Leu Gln Glu Ile Val Arg Ser Phe Ser Gly Thr Thr Cys Gln Pro Ile
         35                  40                  45

Gln His Met Leu Arg Arg Ile Cys Val Gln Leu Cys Asp Leu Ala Ser
     50                  55                  60

Pro Thr Ala Leu Leu Ile Met Arg Thr Val Leu Asp Leu Ile Val Glu
 65                  70                  75                  80

Asp Leu Gln Ser Thr Ser Glu Asp Lys Glu Lys Gln Tyr Thr Ser Gln
                 85                  90                  95

Thr Thr Arg Leu Leu Ala Leu Leu Asp Ala Leu Ala Ser His Lys Ala
            100                 105                 110

Cys Lys Leu Ala Ile Leu His Leu Ile Asn Gly Thr Ile Lys Gly Asp
        115                 120                 125

Glu Arg Tyr Ala Glu Ile Phe Gln Asp Leu Leu Ala Leu Val Arg Ser
    130                 135                 140

Pro Gly Asp Ser Val Ile Arg Gln Gln Cys Val Glu Tyr Val His Pro
145                 150                 155                 160

Phe Cys Ser Leu Ser Val Leu Ser Ala Pro Glu Ser Leu Gln Asn Leu
                165                 170                 175

Leu 




<210> 2065
<211> 231
<212> PRT
<213> Homo sapiens

<400> 2065
Met Gly Glu His Thr Val Asn Glu Ser Ala Ile Phe His Gly Trp Val
  1               5                  10                  15

Leu Gln Lys Val Ser Gln Phe Leu Gln Val Leu Glu Thr Asp Leu Tyr
             20                  25                  30

Arg Gly Ile Gly Gly His Leu Asp Ser Leu Leu Gly Gln Cys Met Tyr
         35                  40                  45

Phe Gly Leu Ser Phe Ser Arg Val Gly Ala Asp Phe Arg Gly Gln Leu
     50                  55                  60

Ala Pro Val Phe Gln Arg Val Ala Ile Ser Thr Phe Gln Lys Ala Ile
 65                  70                  75                  80

Gln Glu Thr Val Glu Lys Phe Gln Glu Glu Met Asn Ser Tyr Met Leu
                 85                  90                  95

Ile Ser Ala Pro Ala Ile Leu Gly Thr Ser Asn Met Pro Ala Ala Val
            100                 105                 110

Pro Ala Thr Gln Pro Gly Thr Leu Gln Pro Pro Met Val Leu Leu Asp
        115                 120                 125

Phe Pro Pro Leu Ala Cys Phe Leu Asn Asn Ile Leu Val Ala Phe Asn
    130                 135                 140

Asp Leu Arg Leu Cys Cys Pro Val Ala Leu Ala Gln Asp Val Thr Gly
145                 150                 155                 160

Ala Leu Glu Asp Ala Leu Ala Lys Val Thr Lys Ile Ile Leu Ala Phe
                165                 170                 175

His Arg Ala Glu Glu Ala Ala Phe Ser Ser Gly Glu Gln Glu Leu Phe
            180                 185                 190

Val Gln Phe Cys Thr Val Phe Leu Glu Asp Leu Val Pro Tyr Leu Asn
        195                 200                 205

Arg Cys Leu Gln Val Leu Phe Pro Pro Ala Gln Ile Ala Gln Thr Leu
    210                 215                 220

Gly Lys Arg Met Lys Ile Leu 
225                 230



<210> 2066
<211> 226
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (224)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2066
Met Ala Ala Gly Leu Phe Gly Leu Ser Ala Arg Arg Leu Leu Ala Ala
  1               5                  10                  15

Ala Ala Thr Arg Gly Leu Pro Ala Ala Arg Val Arg Trp Glu Ser Ser
             20                  25                  30

Phe Ser Arg Thr Val Val Ala Pro Ser Ala Val Ala Gly Lys Arg Pro
         35                  40                  45

Pro Glu Pro Thr Thr Pro Trp Gln Glu Asp Pro Glu Pro Glu Asp Glu
     50                  55                  60

Asn Leu Tyr Glu Lys Asn Pro Asp Ser His Gly Tyr Asp Lys Asp Pro
 65                  70                  75                  80

Val Leu Asp Val Trp Asn Met Arg Leu Val Phe Phe Phe Gly Val Ser
                 85                  90                  95

Ile Ile Leu Val Leu Gly Ser Thr Phe Val Ala Tyr Leu Pro Asp Tyr
            100                 105                 110

Arg Cys Thr Gly Cys Pro Arg Ala Trp Asp Gly Met Lys Glu Trp Ser
        115                 120                 125

Arg Arg Glu Ala Glu Arg Leu Val Lys Tyr Arg Glu Pro Met Ala Phe
    130                 135                 140

Pro Ser Trp Asn Pro Thr Ala Ser Thr Pro Ala Arg Ser Ser Cys Gln
145                 150                 155                 160

Arg Met Ser Asp Gln Leu Leu Ser Gly Ala Gln Glu Ala Pro Pro Ser
                165                 170                 175

Pro Pro Pro Ala Cys His Ser Asp Leu Phe Ser Glu His Leu Ile Lys
            180                 185                 190

Gly Ala Glu Ser Leu Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
        195                 200                 205

Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Gly Arg Pro Xaa Xaa
    210                 215                 220

Lys Ser 
225



<210> 2067
<211> 225
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (212)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2067
Met Gly Asn Leu Pro Ser Ser Gln Asn Ser Ala Arg Gly Leu Phe Gly
  1               5                  10                  15

Leu Ser Ala Arg Arg Leu Leu Ala Ala Ala Ala Thr Arg Gly Leu Pro
             20                  25                  30

Ala Ala Arg Val Arg Trp Glu Ser Ser Phe Ser Arg Thr Val Val Ala
         35                  40                  45

Pro Ser Ala Val Ala Gly Lys Arg Pro Pro Glu Pro Thr Thr Pro Trp
     50                  55                  60

Gln Glu Asp Pro Glu Pro Glu Asp Glu Asn Leu Tyr Glu Lys Asn Pro
 65                  70                  75                  80

Asp Ser His Gly Tyr Asp Lys Asp Pro Val Leu Asp Val Trp Asn Met
                 85                  90                  95

Arg Leu Val Phe Phe Phe Gly Val Ser Ile Ile Leu Val Leu Gly Ser
            100                 105                 110

Thr Phe Val Ala Tyr Leu Pro Asp Tyr Arg Met Lys Glu Trp Ser Arg
        115                 120                 125

Arg Glu Ala Glu Arg Leu Val Lys Tyr Arg Glu Pro Met Ala Phe Pro
    130                 135                 140

Ser Trp Asn Pro Thr Ala Ser Thr Pro Ala Arg Ser Ser Cys Gln Arg
145                 150                 155                 160

Met Ser Asp Gln Leu Leu Ser Gly Ala Gln Glu Ala Pro Pro Ser Pro
                165                 170                 175

Pro Pro Ala Cys His Ser Asp Leu Phe Ser Glu His Leu Ile Lys Gly
            180                 185                 190

Ala Glu Ser Leu Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
        195                 200                 205

Lys Lys Lys Xaa Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Xaa Gly
    210                 215                 220

Gly 
225



<210> 2068
<211> 106
<212> PRT
<213> Homo sapiens

<400> 2068
Met Ser Thr Asn Asn Met Ser Asp Pro Arg Arg Pro Asn Lys Val Leu
  1               5                  10                  15

Arg Tyr Lys Pro Pro Pro Ser Glu Cys Asn Pro Ala Leu Asp Asp Pro
             20                  25                  30

Thr Pro Asp Tyr Met Asn Leu Leu Gly Met Ile Phe Ser Met Cys Gly
         35                  40                  45

Leu Met Leu Lys Leu Lys Trp Cys Ala Trp Val Ala Val Tyr Cys Ser
     50                  55                  60

Phe Ile Ser Phe Ala Asn Ser Arg Ser Ser Glu Asp Thr Lys Gln Met
 65                  70                  75                  80

Met Ser Ser Phe Met Leu Ser Ile Ser Ala Val Val Met Ser Tyr Leu
                 85                  90                  95

Gln Asn Pro Gln Pro Met Thr Pro Pro Trp 
            100                 105



<210> 2069
<211> 329
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (265)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (269)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2069
Met Glu Leu His Ile Leu Glu His Arg Val Arg Val Leu Ser Val Ala
  1               5                  10                  15

Arg Pro Gly Leu Trp Leu Tyr Thr His Pro Leu Ile Lys Leu Leu Phe
             20                  25                  30

Leu Pro Arg Arg Ser Arg Cys Lys Phe Phe Ser Leu Thr Glu Thr Pro
         35                  40                  45

Glu Asp Tyr Thr Leu Met Val Asp Glu Glu Gly Phe Lys Glu Leu Pro
     50                  55                  60

Pro Ser Glu Phe Leu Gln Val Ala Glu Ala Thr Trp Leu Val Leu Asn
 65                  70                  75                  80

Val Ser Ser His Ser Gly Ala Ala Val Gln Ala Ala Gly Val Thr Lys
                 85                  90                  95

Ile Ala Arg Ser Val Ile Ala Pro Leu Ala Glu His His Val Ser Val
            100                 105                 110

Leu Met Leu Ser Thr Tyr Gln Thr Asp Phe Ile Leu Val Arg Glu Gln
        115                 120                 125

Asp Leu Ser Val Val Ile His Thr Leu Ala Gln Glu Phe Asp Ile Tyr
    130                 135                 140

Arg Glu Val Gly Gly Glu Pro Val Pro Val Thr Arg Asp Asp Ser Ser
145                 150                 155                 160

Asn Gly Phe Pro Arg Thr Gln His Gly Pro Ser Pro Thr Val His Pro
                165                 170                 175

Ile Gln Ser Pro Gln Asn Arg Phe Cys Val Leu Thr Leu Asp Pro Glu
            180                 185                 190

Thr Leu Pro Ala Ile Ala Thr Thr Leu Ile Asp Val Leu Phe Tyr Ser
        195                 200                 205

His Ser Thr Pro Lys Glu Ala Ala Ser Ser Ser Pro Glu Pro Ser Ser
    210                 215                 220

Ile Thr Phe Phe Ala Phe Ser Leu Ile Glu Gly Tyr Ile Ser Ile Val
225                 230                 235                 240

Met Asp Ala Glu Thr Gln Lys Lys Phe Pro Ser Asp Leu Leu Leu Thr
                245                 250                 255

Ser Ser Ser Gly Glu Leu Trp Arg Xaa Val Arg Ile Xaa Gly Gln Pro
            260                 265                 270

Leu Gly Phe Asp Glu Cys Gly Ile Val Ala Gln Ile Ala Gly Pro Leu
        275                 280                 285

Ala Ala Ala Asp Ile Ser Ala Tyr Tyr Ile Ser Thr Phe Asn Phe Asp
    290                 295                 300

His Ala Leu Val Pro Glu Asp Gly Ile Gly Ser Val Ile Glu Val Leu
305                 310                 315                 320

Gln Arg Arg Gln Glu Gly Leu Ala Ser 
                325



<210> 2070
<211> 123
<212> PRT
<213> Homo sapiens

<400> 2070
Met Ala Thr Ala Ala Gly Ala Thr Tyr Phe Gln Arg Gly Ser Leu Phe
  1               5                  10                  15

Trp Phe Thr Val Ile Thr Leu Ser Phe Gly Tyr Tyr Thr Trp Val Val
             20                  25                  30

Phe Trp Pro Gln Ser Ile Pro Tyr Gln Asn Leu Gly Pro Leu Gly Pro
         35                  40                  45

Phe Thr Gln Tyr Leu Val Asp His His His Thr Leu Leu Cys Asn Gly
     50                  55                  60

Tyr Trp Leu Ala Trp Leu Ile His Val Gly Glu Ser Leu Tyr Ala Ile
 65                  70                  75                  80

Val Leu Cys Lys His Lys Gly Ile Thr Ser Gly Arg Ala Gln Leu Leu
                 85                  90                  95

Trp Phe Leu Gln Thr Phe Phe Phe Gly Ile Ala Ser Leu Thr Ile Leu
            100                 105                 110

Ile Ala Tyr Lys Arg Lys Arg Gln Lys Gln Thr 
        115                 120



<210> 2071
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2071
Met Lys Asn Arg Asn Leu Phe Pro Thr Val Leu Lys Val Gly Gly Ser
  1               5                  10                  15

Pro Lys Ser Arg Leu Gln Gln Ile Gln Cys Leu Ile Ser Cys Pro Leu
             20                  25                  30

Leu Ser Arg Trp Ser Leu Val Ser Val Ser Ser Leu Gly Arg Arg Asn
         35                  40                  45

Glu Leu Ala Pro Leu Ser Pro Tyr Ile Lys Ser Leu Ile Leu Ser Ile
     50                  55                  60

Arg Val Glu Leu Val Trp Pro Asn His Leu Met Lys Ala Pro Pro Leu
 65                  70                  75                  80

Tyr Phe Xaa Phe Leu Val Glu Met Gly Ser His Cys Val Ala Gln Ala
                 85                  90                  95

Gly Val Glu Phe Leu Gly Ser Met Ile Leu Leu Leu Gly Pro Arg Asn
            100                 105                 110

Ala Val Val Thr Gly Val Ser His Thr Ser 
        115                 120



<210> 2072
<211> 169
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2072
Met Arg Pro Ala Gly Pro Cys Ala Pro Pro Thr Trp Pro Ala Pro Ser
  1               5                  10                  15

Thr Thr Thr Ser Thr Cys Thr Ser Arg Arg Ala Gly Cys Thr Ala Ser
             20                  25                  30

Ser Ala Ser Tyr Ser Thr Leu Ala Ala Ala Cys Ser Leu Arg Arg Ser
         35                  40                  45

Gly Val Arg Trp Pro Pro Ser Ser Ala Tyr Ser Thr Trp Ala Phe Ala
     50                  55                  60

Ser Cys Cys Ala Ser Ser Ala Ser Cys Xaa Val Leu Leu Leu Leu Leu
 65                  70                  75                  80

Gly Arg Arg Arg Val Asp Xaa Arg Leu Val Asn Glu Leu Leu Val Tyr
                 85                  90                  95

Gly Ile His Val Thr Met Leu Leu Val Gly Gly Trp Ala Gly Ala Ser
            100                 105                 110

Trp Ser Ser Trp Thr Cys Glu Gly Arg Gly Cys Glu Leu Asp Val Ser
        115                 120                 125

Ser Arg Pro Val Ala Val Phe Ser Pro Trp Val Gly Ser Ala Ser Ala
    130                 135                 140

Phe Pro Ser Pro Ile Pro Gln Ala Val Ala Ala Ala Arg Arg Pro Arg
145                 150                 155                 160

Arg Glu Lys Lys Gly Leu Arg Leu Leu 
                165



<210> 2073
<211> 165
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2073
Met Asp Ser Ser Arg Ala Arg Gln Gln Leu Arg Arg Arg Phe Leu Leu
  1               5                  10                  15

Leu Pro Asp Ala Glu Ala Gln Leu Asp Arg Glu Gly Asp Ala Gly Pro
             20                  25                  30

Glu Thr Ser Thr Ala Val Glu Lys Lys Glu Lys Pro Leu Pro Arg Leu
         35                  40                  45

Asn Ile His Ser Gly Phe Trp Ile Leu Ala Ser Ile Val Val Thr Tyr
     50                  55                  60

Tyr Val Asp Phe Phe Lys Thr Leu Lys Glu Asn Phe His Thr Ser Ser
 65                  70                  75                  80

Trp Phe Leu Cys Gly Ser Ala Leu Leu Leu Val Ser Leu Ser Ile Ala
                 85                  90                  95

Phe Tyr Cys Ile Val Tyr Leu Glu Trp Tyr Cys Gly Ile Gly Glu Tyr
            100                 105                 110

Asp Val Lys Tyr Pro Ala Leu Ile Pro Ile Thr Thr Ala Ser Phe Ile
        115                 120                 125

Ala Ala Gly Ile Cys Phe Asn Ile Ala Leu Trp His Val Trp Ser Phe
    130                 135                 140

Phe Thr Pro Leu Leu Leu Phe Thr Gln Phe Met Gly Val Val Met Phe
145                 150                 155                 160

Ile Thr Xaa Leu Gly 
                165



<210> 2074
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2074
Met Thr Thr Phe Leu Tyr Arg Ile Leu Pro Gln His Val Asn Cys Pro
  1               5                  10                  15

Gly Gly Ile Asn Ala Trp Asn Thr Ile Thr Ser Tyr Ile Asp Asn Gln
             20                  25                  30

Ile Cys Gln Gly Gln Lys Asn Leu Cys Asn Asn Thr Gly Asp Pro Glu
         35                  40                  45

Met Cys Pro Glu Asn Gly Ser Cys Val Pro Asp Gly Pro Gly Leu Leu
     50                  55                  60

Gln Cys Val Cys Ala Asp Gly Phe His Gly Tyr Lys Cys Met Arg Gln
 65                  70                  75                  80

Gly Ser Phe Ser Leu Leu Met Phe Phe Gly Ile Leu Gly Ala Thr Thr
                 85                  90                  95

Leu Ser Val Ser Ile Leu Xaa Leu Gly Asp Pro Ala Pro Glu Lys Pro
            100                 105                 110

Arg Leu His Glu Leu His Arg Ser Tyr His 
        115                 120



<210> 2075
<211> 210
<212> PRT
<213> Homo sapiens

<400> 2075
Met Leu His Val Phe Val Leu Gly Glu Trp Gln Pro Ile Glu Tyr Gly
  1               5                  10                  15

Lys Lys Lys Leu Lys Tyr Leu Pro Tyr Asn His Gln His Glu Tyr Phe
             20                  25                  30

Phe Leu Ile Gly Pro Pro Leu Leu Ile Pro Met Tyr Phe Gln Tyr Gln
         35                  40                  45

Ile Ile Met Thr Met Ile Val His Lys Asn Trp Val Asp Leu Ala Trp
     50                  55                  60

Ala Val Ser Tyr Tyr Ile Arg Phe Phe Ile Thr Tyr Ile Pro Phe Tyr
 65                  70                  75                  80

Gly Ile Leu Gly Ala Leu Leu Phe Leu Asn Phe Ile Arg Phe Leu Glu
                 85                  90                  95

Ser His Trp Phe Val Trp Val Thr Gln Met Asn His Ile Val Met Glu
            100                 105                 110

Ile Asp Gln Glu Ala Tyr Arg Asp Trp Phe Ser Ser Gln Leu Thr Ala
        115                 120                 125

Thr Cys Asn Val Glu Gln Ser Phe Phe Asn Asp Trp Phe Ser Gly His
    130                 135                 140

Leu Asn Phe Gln Ile Glu His His Leu Phe Pro Thr Met Pro Arg His
145                 150                 155                 160

Asn Leu His Lys Ile Ala Pro Leu Val Lys Ser Leu Cys Ala Lys His
                165                 170                 175

Gly Ile Glu Tyr Gln Glu Lys Pro Leu Leu Arg Ala Leu Leu Asp Ile
            180                 185                 190

Ile Arg Ser Leu Lys Lys Ser Gly Lys Leu Trp Leu Asp Ala Tyr Leu
        195                 200                 205

His Lys 
    210



<210> 2076
<211> 176
<212> PRT
<213> Homo sapiens

<400> 2076
Met Pro Gly Ser Leu Arg Lys Met Pro Val Trp Leu Pro Ile Val Ile
  1               5                  10                  15

Leu Leu Val Ala Met Ala Ser Ile Gln Gly Gly Ala Ser Leu Ala Lys
             20                  25                  30

Ser Leu Phe Pro Leu Val Gly Ala Pro Gly Val Thr Ala Leu Arg Leu
         35                  40                  45

Ala Leu Gly Thr Leu Ile Leu Ile Ala Phe Phe Lys Pro Trp Arg Leu
     50                  55                  60

Arg Phe Ala Lys Glu Gln Arg Leu Pro Leu Leu Phe Tyr Gly Val Ser
 65                  70                  75                  80

Leu Gly Gly Met Asn Tyr Leu Phe Tyr Leu Ser Ile Gln Thr Val Pro
                 85                  90                  95

Leu Gly Ile Ala Val Ala Leu Glu Phe Thr Gly Pro Leu Ala Val Ala
            100                 105                 110

Leu Phe Ser Ser Arg Arg Pro Val Asp Phe Val Trp Val Val Leu Ala
        115                 120                 125

Val Leu Gly Leu Trp Phe Leu Leu Pro Leu Gly Gln Asp Val Ser His
    130                 135                 140

Val Asp Leu Thr Gly Cys Ala Leu Ala Leu Gly Ala Gly Ala Cys Trp
145                 150                 155                 160

Ala Ile Tyr Ile Leu Ser Gly Gln Arg Ala Gly Ala Glu His Gly Pro
                165                 170                 175






<210> 2077
<211> 114
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2077
Met Thr His Leu Ile Glu Tyr Asp Arg His Xaa Lys Ser Arg Leu Xaa
  1               5                  10                  15

Pro Leu Gln His Leu Tyr Leu Leu Pro Ala Asp His Ser Arg Asn Ala
             20                  25                  30

Ala Glu Arg Phe Pro Gly Ala Trp Phe Gln Xaa Pro Thr Val Asp Ser
         35                  40                  45

Glu Ala Ser Ala Phe Ala Gly Gly Leu Pro Val Ile Phe Trp Ser Trp
     50                  55                  60

Ala Gly Leu Val Gly Phe Pro Phe Val Trp Pro Val Ser Xaa Cys Leu
 65                  70                  75                  80

Asn Pro Leu Ser Phe Ile Lys Ser Lys Thr Lys Glu Lys Lys Lys Lys
                 85                  90                  95

Lys Lys Lys Lys Phe Gly Gly Gly Xaa Arg Tyr Pro Ile Gly Pro Leu
            100                 105                 110

Gly Gly 




<210> 2078
<211> 338
<212> PRT
<213> Homo sapiens

<400> 2078
Met Val Met Ser Leu Leu Ser Ala Asn Thr Pro Glu Glu Asp Gln Arg
  1               5                  10                  15

Thr Tyr Val Phe Arg Ala Gln Ser Ala Glu Met Lys Glu Arg Gly Gly
             20                  25                  30

Asn Gln Thr Ser Gly Ile Asp Phe Phe Ile Thr Gln Glu Arg Ile Val
         35                  40                  45

Phe Leu Asp Thr Gln Pro Ile Leu Ser Pro Ser Ile Leu Asp His Leu
     50                  55                  60

Ile Asn Asn Asp Arg Lys Leu Pro Pro Glu Tyr Asn Leu Pro His Thr
 65                  70                  75                  80

Tyr Val Glu Met Gln Ser Leu Gln Ile Ala Ala Phe Leu Phe Thr Val
                 85                  90                  95

Cys His Val Val Ile Val Val Gln Asp Trp Phe Thr Asp Leu Ser Leu
            100                 105                 110

Tyr Arg Phe Leu Gln Thr Ala Glu Met Val Lys Pro Ser Thr Pro Ser
        115                 120                 125

Pro Ser His Glu Ser Ser Ser Ser Ser Gly Ser Asp Glu Gly Thr Glu
    130                 135                 140

Tyr Tyr Pro His Leu Val Phe Leu Gln Asn Lys Ala Arg Arg Glu Asp
145                 150                 155                 160

Phe Cys Pro Arg Lys Leu Arg Gln Met His Leu Met Ile Asp Gln Leu
                165                 170                 175

Met Ala His Ser His Leu Arg Tyr Lys Gly Thr Leu Ser Met Leu Gln
            180                 185                 190

Cys Asn Val Phe Pro Gly Leu Pro Pro Asp Phe Leu Asp Ser Glu Val
        195                 200                 205

Asn Leu Phe Leu Val Pro Phe Met Asp Ser Glu Ala Glu Ser Glu Asn
    210                 215                 220

Pro Pro Arg Ala Gly Pro Gly Ser Ser Pro Leu Phe Ser Leu Leu Pro
225                 230                 235                 240

Gly Tyr Arg Gly His Pro Ser Phe Gln Ser Leu Val Ser Lys Leu Arg
                245                 250                 255

Ser Gln Val Met Ser Met Ala Arg Pro Gln Leu Ser His Thr Ile Leu
            260                 265                 270

Thr Glu Lys Asn Trp Phe His Leu Arg Cys Pro Asp Leu Gly Trp Gly
        275                 280                 285

Glu Lys Val Leu Cys Ser Gly Arg Val Gln Pro Pro Ala Gly Leu Arg
    290                 295                 300

Pro Arg Arg Gly Met Ser Cys Arg Gly Pro Pro Gly Ser Ala Val Tyr
305                 310                 315                 320

Cys Glu Gly Ala Gln Met Ser Ile Pro Arg Trp Gly Gly Glu Arg Gln
                325                 330                 335

Gln Ala 




<210> 2079
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2079
Met Val Tyr Glu Lys Leu Gly Glu Gln Val Phe Gly Thr Thr Gly Lys
  1               5                  10                  15

Phe Val Ile Phe Gly Ala Thr Ser Leu Gln Asn Thr Gly Ala Met Leu
             20                  25                  30

Ser Tyr Leu Phe Ile Val Lys Asn Glu Leu Pro Ser Ala Ile Lys Phe
         35                  40                  45

Leu Met Gly Lys Glu Glu Thr Phe Ser Ala Trp Tyr Val Asp Gly Arg
     50                  55                  60

Val Leu Val Val Ile Val Thr Phe Gly Ile Ile Leu Pro Leu Cys Leu
 65                  70                  75                  80

Xaa Glu Glu Leu Arg Val Ser Xaa Ala Ile Thr Xaa Trp Asp Phe Pro
                 85                  90                  95

Leu Glu Leu Xaa Trp Val Phe Phe 
            100



<210> 2080
<211> 332
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (308)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (309)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2080
Met Ala Ala Ala Gln Glu Ala Asp Gly Ala Arg Ser Ala Val Val Ala
  1               5                  10                  15

Ala Gly Gly Gly Ser Ser Gly Gln Val Thr Ser Asn Gly Ser Ile Gly
             20                  25                  30

Arg Asp Pro Pro Ala Glu Thr Gln Pro Gln Asn Pro Pro Ala Gln Pro
         35                  40                  45

Ala Pro Asn Ala Trp Gln Val Ile Lys Gly Val Leu Phe Arg Ile Phe
     50                  55                  60

Ile Ile Trp Ala Ile Ser Ser Trp Phe Arg Arg Gly Pro Ala Pro Gln
 65                  70                  75                  80

Asp Gln Ala Gly Pro Gly Gly Ala Pro Arg Val Ala Ser Arg Asn Leu
                 85                  90                  95

Phe Pro Lys Asp Thr Leu Met Asn Leu His Val Tyr Ile Ser Glu His
            100                 105                 110

Glu His Phe Thr Asp Phe Asn Ala Thr Ser Ala Leu Phe Trp Glu Gln
        115                 120                 125

His Asp Leu Val Tyr Gly Asp Trp Thr Ser Gly Glu Asn Ser Asp Gly
    130                 135                 140

Cys Tyr Glu His Phe Ala Glu Leu Asp Ile Pro Gln Ser Val Gln Gln
145                 150                 155                 160

Asn Gly Ser Ile Tyr Ile His Val Tyr Phe Thr Lys Ser Gly Phe His
                165                 170                 175

Pro Asp Pro Arg Gln Lys Ala Leu Tyr Arg Arg Leu Ala Thr Val His
            180                 185                 190

Met Ser Arg Met Ile Asn Lys Tyr Lys Arg Arg Arg Phe Gln Lys Thr
        195                 200                 205

Lys Asn Leu Leu Thr Gly Glu Thr Glu Ala Asp Pro Glu Met Ile Lys
    210                 215                 220

Arg Ala Glu Asp Tyr Gly Pro Val Glu Val Ile Ser His Trp His Pro
225                 230                 235                 240

Asn Ile Thr Ile Asn Ile Val Asp Asp His Thr Pro Trp Val Lys Gly
                245                 250                 255

Ser Val Pro Pro Pro Leu Asp Gln Tyr Val Lys Phe Asp Ala Val Ser
            260                 265                 270

Gly Asp Tyr Tyr Pro Ile Ile Tyr Phe Asn Asp Tyr Trp Asn Leu Gln
        275                 280                 285

Lys Asp Tyr Tyr Pro Ile Asn Glu Ser Leu Ala Ser Leu Pro Leu Arg
    290                 295                 300

Ser Pro Ser Xaa Xaa Ser Arg Phe Gly Ala Gly Ser Ser Met Leu Pro
305                 310                 315                 320

Arg Ala Pro Ser Arg Pro Gly Asn Phe Leu Gly Asp 
                325                 330



<210> 2081
<211> 204
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (191)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2081
Met Leu Gln Ser Thr Lys Ser Pro Trp Asn Phe Leu Gly Asp Glu Leu
  1               5                  10                  15

Tyr Glu Gln Ser Asp Glu Glu Gln Asp Ser Val Lys Val Ala Leu Leu
             20                  25                  30

Glu Thr Asn Pro Tyr Leu Leu Ala Leu Thr Ile Ile Val Ser Ile Val
         35                  40                  45

His Ser Val Phe Glu Phe Leu Ala Phe Lys Asn Asp Ile Gln Phe Trp
     50                  55                  60

Asn Ser Arg Gln Ser Leu Glu Gly Leu Ser Val Arg Ser Val Phe Phe
 65                  70                  75                  80

Gly Val Phe Gln Ser Phe Val Val Leu Leu Tyr Ile Leu Asp Asn Glu
                 85                  90                  95

Thr Asn Phe Val Val Gln Val Ser Val Phe Ile Gly Val Leu Ile Asp
            100                 105                 110

Leu Trp Lys Ile Thr Lys Val Met Asp Val Arg Leu Asp Arg Glu His
        115                 120                 125

Arg Val Ala Gly Ile Phe Pro Arg Leu Ser Phe Lys Asp Lys Ser Thr
    130                 135                 140

Tyr Ile Glu Ser Ser Thr Lys Val Tyr Asp Asp Met Ala Phe Arg Tyr
145                 150                 155                 160

Leu Ser Trp Ile Leu Phe Pro Leu Leu Gly Cys Tyr Ala Val Tyr Ser
                165                 170                 175

Leu Leu Tyr Leu Glu His Lys Gly Trp Xaa Ser Trp Val Leu Xaa Met
            180                 185                 190

Leu Tyr Gly Phe Leu Leu Thr Ser Ala Ser Ser Pro 
        195                 200



<210> 2082
<211> 381
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (290)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2082
Met Asp Thr Glu Glu Gln Glu Glu Phe Lys Ala Ala Asp Val Glu Gln
  1               5                  10                  15

Leu Lys Pro Glu Glu Ile Lys Ser Gly Thr Thr Ala Pro Leu Gly Phe
             20                  25                  30

Asp Glu Met Glu Val Glu Ile Gln Thr Val Lys Thr Glu Glu Asp Gln
         35                  40                  45

Asp Pro Arg Thr Asp Lys Ala His Lys Glu Thr Glu Asn Glu Lys Pro
     50                  55                  60

Glu Arg Ser Arg Glu Ser Thr Ile His Thr Ala His Gln Phe Leu Met
 65                  70                  75                  80

Asp Thr Ile Phe Gln Pro Phe Leu Lys Asp Val Asn Glu Leu Arg Gln
                 85                  90                  95

Glu Leu Glu Arg Gln Leu Glu Met Trp Gln Pro Arg Glu Ser Gly Asn
            100                 105                 110

Pro Glu Glu Glu Lys Val Ala Ala Glu Met Trp Gln Ser Tyr Leu Ile
        115                 120                 125

Leu Thr Ala Pro Leu Ser Gln Arg Leu Cys Glu Glu Leu Arg Leu Ile
    130                 135                 140

Leu Glu Pro Thr Gln Ala Ala Lys Leu Lys Gly Asp Tyr Arg Thr Gly
145                 150                 155                 160

Lys Arg Leu Asn Ile Arg Lys Val Ile Pro Tyr Ile Ala Ser Gln Phe
                165                 170                 175

Arg Lys Asp Lys Ile Trp Leu Arg Arg Thr Lys Pro Ser Lys Arg Gln
            180                 185                 190

Tyr Gln Ile Cys Leu Ala Ile Asp Asp Ser Ser Ser Met Val Asp Asn
        195                 200                 205

His Thr Lys Gln Leu Ala Phe Glu Ser Leu Ala Val Ile Gly Asn Ala
    210                 215                 220

Leu Thr Leu Leu Glu Val Gly Gln Ile Ala Val Cys Ser Phe Gly Glu
225                 230                 235                 240

Ser Val Lys Leu Leu His Pro Phe His Glu Gln Phe Ser Asp Tyr Ser
                245                 250                 255

Gly Ser Gln Ile Leu Arg Leu Cys Lys Phe Gln Gln Lys Lys Thr Lys
            260                 265                 270

Ile Ala Gln Phe Leu Glu Ser Val Ala Asn Met Phe Ala Ala Ala Gln
        275                 280                 285

Gln Xaa Ser Gln Asn Ile Ser Ser Glu Thr Ala Gln Leu Leu Leu Val
    290                 295                 300

Val Ser Asp Gly Arg Gly Leu Phe Leu Glu Gly Lys Glu Arg Val Leu
305                 310                 315                 320

Ala Ala Val Gln Ala Ala Gly Met Gln Ile Ser Leu Ser Ser Leu Leu
                325                 330                 335

Tyr Trp Thr Ile Pro Val His Gly Ile Leu Ser Trp Thr Leu Lys Tyr
            340                 345                 350

Arg Tyr Leu Lys Asp Leu Glu Arg Cys Leu Lys Ser Asp Pro Thr Trp
        355                 360                 365

Lys Ser Ser His Ser His Thr Ile Ser Phe Phe Glu Met 
    370                 375                 380



<210> 2083
<211> 101
<212> PRT
<213> Homo sapiens

<400> 2083
Met Asn Leu Glu Arg Val Ser Asn Glu Glu Lys Leu Asn Leu Cys Arg
  1               5                  10                  15

Lys Tyr Tyr Leu Gly Gly Phe Ala Phe Leu Pro Phe Leu Trp Leu Val
             20                  25                  30

Asn Ile Phe Trp Phe Phe Arg Glu Ala Phe Leu Val Pro Ala Tyr Thr
         35                  40                  45

Glu Gln Ser Gln Ile Lys Gly Tyr Val Trp Arg Ser Ala Val Gly Phe
     50                  55                  60

Leu Phe Trp Val Ile Val Leu Thr Ser Trp Ile Thr Ile Phe Gln Ile
 65                  70                  75                  80

Tyr Arg Pro Arg Trp Gly Ala Leu Gly Asp Tyr Leu Ser Phe Thr Ile
                 85                  90                  95

Pro Leu Gly Thr Pro 
            100



<210> 2084
<211> 130
<212> PRT
<213> Homo sapiens

<400> 2084
Met Ala Ser Asp Leu Ile Arg Thr Ile Leu Val Val Ala Leu Ile Ser
  1               5                  10                  15

Lys Leu Gly Thr Ala Val Asp Ala Glu Leu Met Pro Ser Gly Ala Ile
             20                  25                  30

Leu Gln Asn Lys Arg Glu Asn Leu Pro Arg Val Cys His Ala Leu Ala
         35                  40                  45

Phe Leu Gly Met Ala Arg Cys Gln Asp Leu Phe Leu Val Arg Leu Gln
     50                  55                  60

Gly Trp Lys Leu Gly Thr Arg Phe Gln Asp Gly Pro Arg Ser Thr Pro
 65                  70                  75                  80

Gln Glu Glu Gly Gly Ser Pro Gln Arg Lys Arg Gly Met Pro Val Gln
                 85                  90                  95

Ile His Phe Leu Leu Lys Ser Phe Leu Ser Ser Pro Ile Thr Phe Ala
            100                 105                 110

Phe Ile Ser Leu Ala Arg Thr Val Ser Leu Ala Thr Ala Ile Cys Lys
        115                 120                 125

Ile Val 
    130



<210> 2085
<211> 153
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2085
Met Glu Asp Ala Lys Phe Tyr Leu Thr Leu Pro Gly Thr Lys Met Glu
  1               5                  10                  15

Met Glu Glu Lys Glu Leu Gln Ala Ser Lys Asn Leu Val Thr Phe Thr
             20                  25                  30

Pro Ser Lys Asp Ser Thr Lys Asp Ser Phe Gln Ile Ala Thr Leu Ile
         35                  40                  45

Cys Ser Thr Lys Leu Thr Gln Asn Val Asp Leu Leu Gly Leu Leu Asn
     50                  55                  60

Trp Arg Ser Asn Ser Gln Asn Ile Lys His Asn Leu Lys Lys Leu Met
 65                  70                  75                  80

Glu Val Asp Gly Gly Glu Ile Val Lys Phe Leu Gln Asp Thr Leu Asp
                 85                  90                  95

Ala Leu Phe Asn Ile Met Met Glu Met Ser Asp Ser Glu Xaa Tyr Asp
            100                 105                 110

Phe Leu Val Phe Asp Ala Leu Val Phe Ile Ile Ser Leu Ile Gly Asp
        115                 120                 125

Xaa Xaa Phe Gln His Phe Asn Pro Val Leu Glu Thr Tyr Ile Tyr Lys
    130                 135                 140

His Phe Ser Ala Thr Leu Ala Tyr Val 
145                 150



<210> 2086
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (23)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2086
Met Ala Glu Glu Phe Met Val Ala Phe Arg Asp Cys Lys Asp His Ile
  1               5                  10                  15

Asp Met Ser Gln Val Glu Xaa Gly Pro Xaa Ala Val Leu His Lys Cys
             20                  25                  30

Leu Xaa Thr Cys Pro Ser Ser Ile Gln Glu Cys Val Thr Glu Gly Leu
         35                  40                  45

Ala Gly Pro Thr Cys Trp Leu Arg His Val Thr Gly Leu Thr Ala Cys
     50                  55                  60

Pro Gly His Cys Gln Gly Ser Met Gly Gln Pro Ser Pro Thr Pro Pro
 65                  70                  75                  80

Trp Ile Phe Leu Ser Ile Thr Ser Phe Leu Thr Ile Cys Ser Leu Pro
                 85                  90                  95

Phe Leu Lys His Leu Met Pro His Arg Ser Pro Ser Gly Asp Trp Ile
            100                 105                 110

Cys Lys Gly Tyr Leu Pro Pro Ser Gly Val 
        115                 120



<210> 2087
<211> 159
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2087
Met Leu Ile Ala Ser Val Trp Arg Gln Arg Gln Phe Pro Pro Gln Leu
  1               5                  10                  15

Gly Pro Gly Xaa Cys Phe Leu Ala Cys Asp Ala Pro Cys Thr Ser Ser
             20                  25                  30

Pro Ser Ser Pro Ala Ser Ala Phe Cys Trp Val Lys Gly Gly Leu Phe
         35                  40                  45

Leu Ser Ser Leu Glu Leu Phe Pro Val Gly Phe Pro Arg Ala His Leu
     50                  55                  60

Leu Val Gln Ser Thr Leu Pro Xaa Pro Arg Pro Glu Arg Ala Phe Thr
 65                  70                  75                  80

Ala Pro Ser Leu Ser Pro Val Thr Leu Gly Phe Cys Leu Gly Arg Ile
                 85                  90                  95

Leu Cys Gln Arg Leu Leu Leu Cys Pro Ser Cys Leu Ala Thr Ala Leu
            100                 105                 110

Ser Ile Asn Gly Tyr Ser Arg Thr Ala Gly Cys Gln Ser Trp Lys Gly
        115                 120                 125

Arg Asp Thr Gly Leu His Lys Gly Lys Leu Leu Glu Ala Leu Gly Gly
    130                 135                 140

Thr Glu Gly Phe Gly Asp Arg Ala Arg Ala Lys Ile Glu Asp Ser 
145                 150                 155



<210> 2088
<211> 147
<212> PRT
<213> Homo sapiens

<400> 2088
Met Val Ala Met Val Glu Val Gln Leu Asp Ala Asp His Asp Tyr Pro
  1               5                  10                  15

Pro Gly Leu Leu Ile Ala Phe Ser Ala Cys Thr Thr Val Leu Val Ala
             20                  25                  30

Val His Leu Phe Ala Leu Met Ile Ser Thr Cys Ile Leu Pro Asn Ile
         35                  40                  45

Glu Ala Val Ser Asn Val His Asn Leu Asn Ser Val Lys Glu Ser Pro
     50                  55                  60

His Glu Arg Met His Arg His Ile Glu Leu Ala Trp Ala Phe Ser Thr
 65                  70                  75                  80

Val Ile Gly Thr Leu Leu Phe Leu Ala Glu Val Val Leu Leu Cys Trp
                 85                  90                  95

Val Lys Phe Leu Pro Leu Lys Lys Gln Pro Gly Gln Pro Arg Pro Thr
            100                 105                 110

Ser Lys Pro Pro Ala Ser Gly Ala Gln Pro Thr Ser Ala Pro Ala Ala
        115                 120                 125

Ser Pro Arg Ala Arg Gln Leu Pro Ser Pro Arg Pro Pro Ser Trp Cys
    130                 135                 140

Pro Ser Ala 
145



<210> 2089
<211> 228
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (224)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2089
Met Cys Ala Gln Tyr Cys Ile Ser Phe Ala Asp Val Glu Lys Ala His
  1               5                  10                  15

Ile Asn Ile Arg Asp Ser Ile His Leu Thr Pro Val Leu Thr Ser Ser
             20                  25                  30

Ile Leu Asn Gln Leu Thr Gly Arg Asn Leu Phe Phe Lys Cys Glu Leu
         35                  40                  45

Phe Gln Lys Thr Gly Ser Phe Lys Ile Arg Gly Ala Leu Asn Ala Val
     50                  55                  60

Arg Ser Leu Val Pro Asp Ala Leu Glu Arg Lys Pro Lys Ala Val Val
 65                  70                  75                  80

Thr His Ser Ser Gly Asn His Gly Gln Ala Leu Thr Tyr Ala Ala Lys
                 85                  90                  95

Leu Glu Gly Ile Pro Ala Tyr Ile Val Val Pro Gln Thr Ala Pro Asp
            100                 105                 110

Cys Lys Lys Leu Ala Ile Gln Ala Tyr Gly Ala Ser Ile Val Tyr Cys
        115                 120                 125

Glu Pro Ser Asp Glu Ser Arg Glu Asn Val Ala Lys Arg Val Thr Glu
    130                 135                 140

Glu Thr Glu Gly Ile Met Val His Pro Asn Gln Glu Pro Ala Val Ile
145                 150                 155                 160

Ala Gly Gln Gly Thr Ile Ala Leu Glu Val Leu Asn Gln Val Pro Leu
                165                 170                 175

Val Asp Ala Leu Val Val Pro Val Gly Gly Gly Gly Met Leu Ala Gly
            180                 185                 190

Ile Ala Ile Thr Val Lys Ala Leu Lys Pro Ser Val Lys Val Tyr Ala
        195                 200                 205

Xaa Xaa Pro Gln Met Gln Met Thr Val Pro Val Gln Ala Glu Gly Xaa
    210                 215                 220

Leu Met Pro Ile 
225



<210> 2090
<211> 422
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (377)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2090
Met Lys Leu Leu Gly Glu Cys Ser Ser Ser Ile Asp Ser Val Lys Arg
  1               5                  10                  15

Leu Glu His Lys Leu Lys Glu Glu Glu Glu Ser Leu Pro Gly Phe Val
             20                  25                  30

Asn Leu His Ser Thr Glu Thr Gln Thr Ala Gly Val Ile Asp Arg Trp
         35                  40                  45

Glu Leu Leu Gln Ala Gln Ala Leu Ser Lys Glu Leu Arg Met Lys Gln
     50                  55                  60

Asn Leu Gln Lys Trp Gln Gln Phe Asn Ser Asp Leu Asn Ser Ile Trp
 65                  70                  75                  80

Ala Trp Leu Gly Asp Thr Glu Glu Glu Leu Glu Gln Leu Gln Arg Leu
                 85                  90                  95

Glu Leu Ser Thr Asp Ile Gln Thr Ile Glu Leu Gln Ile Lys Lys Leu
            100                 105                 110

Lys Glu Leu Gln Lys Ala Val Asp His Arg Lys Ala Ile Ile Leu Ser
        115                 120                 125

Ile Asn Leu Cys Ser Pro Glu Phe Thr Gln Ala Asp Ser Lys Glu Ser
    130                 135                 140

Arg Asp Leu Gln Asp Arg Leu Ser Gln Met Asn Gly Arg Trp Asp Arg
145                 150                 155                 160

Val Cys Ser Leu Leu Glu Glu Trp Arg Gly Leu Leu Gln Asp Ala Leu
                165                 170                 175

Met Gln Cys Gln Gly Phe His Glu Met Ser His Gly Leu Leu Leu Met
            180                 185                 190

Leu Glu Asn Ile Asp Arg Arg Lys Asn Glu Ile Val Pro Ile Asp Ser
        195                 200                 205

Asn Leu Asp Ala Glu Ile Leu Gln Asp His His Lys Gln Leu Met Gln
    210                 215                 220

Ile Lys His Glu Leu Leu Glu Ser Gln Leu Arg Val Ala Ser Leu Gln
225                 230                 235                 240

Asp Met Ser Cys Gln Leu Leu Val Asn Ala Glu Gly Thr Asp Cys Leu
                245                 250                 255

Glu Ala Lys Glu Lys Val His Val Ile Gly Asn Arg Leu Lys Leu Leu
            260                 265                 270

Leu Lys Glu Val Ser Arg His Ile Lys Glu Leu Glu Lys Leu Leu Asp
        275                 280                 285

Val Ser Ser Ser Gln Gln Asp Leu Ser Ser Trp Ser Ser Ala Asp Glu
    290                 295                 300

Leu Asp Thr Ser Gly Ser Val Ser Pro Thr Ser Gly Arg Ser Thr Pro
305                 310                 315                 320

Asn Arg Gln Lys Thr Pro Arg Gly Lys Cys Ser Leu Ser Gln Pro Gly
                325                 330                 335

Pro Ser Val Ser Ser Pro His Ser Arg Ser Thr Lys Gly Gly Ser Asp
            340                 345                 350

Ser Ser Leu Ser Glu Pro Gly Pro Gly Arg Ser Gly Arg Gly Phe Leu
        355                 360                 365

Phe Arg Val Leu Arg Ala Ala Leu Xaa Leu Gln Leu Leu Leu Leu Leu
    370                 375                 380

Leu Ile Gly Leu Ala Cys Leu Val Pro Met Ser Glu Glu Asp Tyr Ser
385                 390                 395                 400

Cys Ala Leu Ser Thr Thr Phe Ala Gly Ile Pro Pro Met Leu Arg Tyr
                405                 410                 415

Thr Asn Gly Leu Ser Leu 
            420



<210> 2091
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2091
Met Asp Gln Gly Arg Arg Arg Ala Asp Gly Thr Trp Ala Gln Gln Gly
  1               5                  10                  15

Leu Val Leu Arg Ala Leu Gly Gly His Gly Trp Glu Gly His Gly Arg
             20                  25                  30

Gly Trp His Pro Cys Arg Ala Arg Gly Ala Thr Gln Gly Ser Asp Ile
         35                  40                  45

Pro Asp Met Leu Gly Ser Pro His Pro Cys Cys Glu Thr Gly Val Pro
     50                  55                  60

Trp Gly His Glu Val Ser Thr Pro Gln Ser Cys Ser Ala Ala Leu Pro
 65                  70                  75                  80

Leu Ala Asp Phe Phe Val Ala His Ile His Phe Leu Ser Ile Ser Ile
                 85                  90                  95

Tyr Phe Ser Phe Tyr Leu Ser Phe Leu Thr Val His Val Xaa Tyr Met
            100                 105                 110

Ile Ile Thr Ile 
        115



<210> 2092
<211> 180
<212> PRT
<213> Homo sapiens

<400> 2092
Met Glu Tyr Gly Gly Thr Phe Arg Lys Arg Glu Asp Leu Arg Gly Arg
  1               5                  10                  15

Leu Phe Trp Val Ala Leu Asp Leu Leu Asp Leu Leu Asp Met Gln Ala
             20                  25                  30

Ser Leu Trp Glu Pro Pro Arg Ser Gly Leu Pro Leu Trp Ala Glu Gly
         35                  40                  45

Leu Thr Phe Phe Tyr Cys Tyr Met Leu Leu Leu Val Leu Pro Cys Val
     50                  55                  60

Ala Leu Ser Glu Val Ser Met Gln Gly Glu His Ile Ala Pro Gln Lys
 65                  70                  75                  80

Met Met Leu Tyr Pro Val Leu Ser Leu Ala Thr Val Asn Val Val Ala
                 85                  90                  95

Val Leu Ala Arg Ala Ala Asn Met Ala Leu Phe Arg Asp Ser Arg Val
            100                 105                 110

Ser Ala Ile Phe Val Gly Lys Asn Val Val Ala Leu Ala Thr Lys Ala
        115                 120                 125

Cys Thr Phe Leu Glu Tyr Arg Arg Gln Val Arg Asp Phe Pro Pro Leu
    130                 135                 140

Ala Leu Ser Leu Glu Leu Gln Pro Pro Pro Pro Gln Arg Asn Ser Val
145                 150                 155                 160

Pro Leu Ala Ala Ala Ala Ala Arg Pro Ala Trp Ala Pro Pro His Val
                165                 170                 175

Leu Ala His Ala 
            180



<210> 2093
<211> 326
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (249)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (253)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (258)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (261)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (316)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2093
Met Val Val Val Gly Ile Leu Leu Ala Tyr Leu Ala Gly Trp Val Leu
  1               5                  10                  15

Glu Trp Arg Trp Leu Ala Val Leu Gly Cys Val Pro Pro Ser Leu Met
             20                  25                  30

Leu Leu Leu Met Cys Phe Met Pro Glu Thr Pro Arg Phe Leu Leu Thr
         35                  40                  45

Gln His Arg Arg Gln Glu Ala Met Ala Ala Leu Arg Phe Leu Trp Gly
     50                  55                  60

Ser Glu Gln Gly Trp Glu Asp Pro Pro Ile Gly Xaa Glu Gln Ser Phe
 65                  70                  75                  80

His Leu Ala Leu Leu Arg Xaa Pro Gly Ile Tyr Lys Pro Phe Ile Ile
                 85                  90                  95

Gly Val Ser Leu Met Ala Phe Gln Gln Leu Ser Gly Val Asn Ala Val
            100                 105                 110

Met Phe Tyr Ala Glu Thr Ile Phe Glu Glu Ala Lys Phe Lys Asp Ser
        115                 120                 125

Ser Leu Ala Ser Val Val Val Gly Val Ile Gln Val Leu Phe Thr Ala
    130                 135                 140

Val Ala Ala Leu Ile Met Asp Arg Ala Gly Arg Arg Leu Leu Leu Val
145                 150                 155                 160

Leu Ser Gly Val Val Met Val Phe Ser Thr Ser Ala Phe Gly Ala Tyr
                165                 170                 175

Phe Lys Leu Thr Gln Gly Gly Pro Gly Asn Ser Ser His Val Ala Ile
            180                 185                 190

Ser Ala Pro Val Ser Ala Gln Pro Val Asp Ala Ser Val Gly Leu Ala
        195                 200                 205

Trp Leu Ala Val Gly Ser Met Cys Leu Phe Ile Ala Gly Phe Ala Val
    210                 215                 220

Gly Trp Gly Pro Ile Pro Trp Leu Leu Met Ser Glu Ile Phe Pro Leu
225                 230                 235                 240

His Val Lys Gly Val Ala Thr Gly Xaa Cys Val Leu Xaa Asn Trp Leu
                245                 250                 255

Met Xaa Phe Leu Xaa Thr Lys Glu Phe Ser Ser Leu Met Glu Val Leu
            260                 265                 270

Arg Pro Tyr Gly Ala Phe Trp Leu Ala Ser Ala Phe Cys Ile Phe Ser
        275                 280                 285

Val Leu Phe Thr Leu Val Cys Ala Leu Lys Leu Lys Glu Arg Leu Trp
    290                 295                 300

Asn Lys Ser Gln Pro Ile Leu Arg Gly Asp Asp Xaa His Ser Leu Arg
305                 310                 315                 320

Gly Met Glu Gln Ala Leu 
                325



<210> 2094
<211> 211
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2094
Met Ala Leu Leu Ile Pro Thr Gly Leu His Gln Val Leu Thr Pro Ser
  1               5                  10                  15

Pro Gly Ser Arg Leu Val Asn Ser Pro Thr Arg Arg Val Arg Phe Ser
             20                  25                  30

Thr Val Thr Leu Thr Ala Ser Met Pro Val Thr Thr Ala Gly Met Phe
         35                  40                  45

Met Ser Gly Phe Phe Pro Ile Met Met Phe Gly Leu Pro Gly Ala Ala
     50                  55                  60

Leu Ala Met Tyr Phe Ala Ala Pro Lys Glu Arg Arg Pro Met Val Gly
 65                  70                  75                  80

Gly Met Leu Leu Ser Val Ala Val Xaa Ala Phe Leu Thr Gly Val Thr
                 85                  90                  95

Glu Pro Leu Glu Phe Leu Phe Met Phe Leu Ala Pro Leu Leu Tyr Leu
            100                 105                 110

Leu His Ala Leu Leu Thr Gly Ile Ser Leu Phe Val Ala Thr Leu Leu
        115                 120                 125

Gly Ile His Ala Gly Phe Ser Phe Ser Ala Gly Ala Ile Asp Tyr Ala
    130                 135                 140

Leu Met Tyr Asn Leu Pro Ala Ala Ser Gln Asn Val Trp Met Leu Leu
145                 150                 155                 160

Val Met Gly Val Ile Phe Phe Ala Ile Tyr Phe Val Val Phe Ser Leu
                165                 170                 175

Val Ile Arg Met Phe Asn Leu Lys Thr Pro Gly Arg Glu Asp Lys Glu
            180                 185                 190

Asp Glu Ile Val Thr Glu Glu Ala Asn Ser Asn Thr Glu Glu Gly Leu
        195                 200                 205

Thr Xaa Leu 
    210



<210> 2095
<211> 193
<212> PRT
<213> Homo sapiens

<400> 2095
Met Gln Gln Ser Val Glu Tyr Glu Arg Lys Lys Phe Gln Glu Ile Leu
  1               5                  10                  15

Glu Arg Gln Pro Asn Ser Leu Asp Phe Val Thr Gln Trp Leu Glu Glu
             20                  25                  30

Ala Ser Glu Asp Leu Met Thr Gln Lys Tyr Lys His Ala Leu Pro Val
         35                  40                  45

Gly Gly Met Ala Ala Gly Ser Gly Asp Met Pro Arg Leu Ser Pro Val
     50                  55                  60

Ala Val Gln Asn Tyr Ala Tyr Leu Lys Leu Leu Lys Trp Asp His Leu
 65                  70                  75                  80

Gln Arg Pro Phe Pro Glu Thr Val Leu Met Asp Gln Ser Arg Phe His
                 85                  90                  95

Glu Leu Gln Leu Gln Leu Glu Gln Leu Thr Ile Leu Gly Ala Val Leu
            100                 105                 110

Leu Val Thr Phe Ser Met Ala Ala Pro Gly Ile Ser Ser Gln Ala Asp
        115                 120                 125

Phe Ala Glu Lys Leu Lys Met Ile Val Lys Ile Leu Leu Thr Asp Met
    130                 135                 140

His Leu Pro Ser Phe His Leu Lys Asp Val Leu Thr Thr Ile Gly Glu
145                 150                 155                 160

Lys Val Cys Leu Glu Val Ser Ser Cys Leu Ser Leu Cys Gly Ser Ser
                165                 170                 175

Pro Phe Thr Thr Asp Lys Glu Thr Val Leu Lys Gly Gln Ile His Ala
            180                 185                 190

Glu 




<210> 2096
<211> 209
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2096
Met Ala Xaa Ser Ser Arg Gly Asn Ala Asp Ser Ile Val Ala Ser Leu
  1               5                  10                  15

Val Leu Met Val Leu Tyr Leu Ile Lys Lys Arg Leu Val Ala Cys Ala
             20                  25                  30

Ala Val Phe Tyr Gly Phe Xaa Val His Met Lys Ile Tyr Pro Val Thr
         35                  40                  45

Tyr Ile Leu Pro Ile Thr Leu His Leu Leu Pro Asp Arg Asp Asn Asp
     50                  55                  60

Lys Ser Leu Arg Gln Phe Arg Tyr Thr Phe Gln Ala Cys Leu Tyr Glu
 65                  70                  75                  80

Leu Leu Lys Lys Leu Cys Asn Arg Ala Val Leu Leu Phe Val Ala Val
                 85                  90                  95

Ala Gly Leu Thr Phe Phe Ala Leu Ser Phe Gly Phe Tyr Tyr Glu Tyr
            100                 105                 110

Gly Trp Glu Phe Leu Glu His Thr Tyr Phe Tyr His Leu Thr Arg Arg
        115                 120                 125

Asp Ile Arg His Asn Phe Ser Pro Tyr Phe Tyr Met Leu Tyr Leu Thr
    130                 135                 140

Ala Glu Ser Lys Trp Ser Phe Ser Leu Gly Ile Ala Ala Phe Leu Pro
145                 150                 155                 160

Gln Leu Ile Leu Leu Ser Ala Val Ser Phe Ala Tyr Tyr Arg Asp Leu
                165                 170                 175

Val Phe Cys Cys Phe Leu His Thr Ser Ile Phe Val Thr Phe Asn Lys
            180                 185                 190

Val Cys Thr Ser Gln Tyr Phe Leu Trp Val Pro Leu Ala Tyr Cys Leu
        195                 200                 205

Leu 




<210> 2097
<211> 139
<212> PRT
<213> Homo sapiens

<400> 2097
Met Arg Pro Pro Ser Ala Phe Ser Ser Tyr Cys His Lys Cys Leu Leu
  1               5                  10                  15

Ala Arg Val Gly Trp Tyr Gly Leu Glu Leu His Ser Thr Val Arg Arg
             20                  25                  30

Val Leu Gln Asp Asp Arg Leu Arg Thr Arg Arg Glu Gly Ile Pro Cys
         35                  40                  45

Thr Met Leu Ala Ser Gln Trp Thr Phe Pro Glu Thr Lys Ser Ile Ile
     50                  55                  60

Ser Lys Leu Met Ala Val Leu Val Phe Gly Ser Leu Ala Pro Val Thr
 65                  70                  75                  80

Leu Gly Ala Asp Glu Asp Arg Cys Leu Leu Leu Val Trp Glu Ser Ile
                 85                  90                  95

Cys His Pro Lys Ile Cys Leu Asn Ser Ile Arg Ile Ile Leu Arg Asn
            100                 105                 110

Cys Ser Tyr Arg Arg Asn Ser Glu Asn Arg Val Tyr Gln Phe Leu Arg
        115                 120                 125

Glu Ile Asp Ile Tyr Lys Gly Asn Leu His Leu 
    130                 135



<210> 2098
<211> 115
<212> PRT
<213> Homo sapiens

<400> 2098
Met Ala Gly Thr Val Leu Gly Val Gly Ala Gly Val Phe Ile Leu Ala
  1               5                  10                  15

Leu Leu Trp Val Ala Val Leu Leu Leu Cys Val Leu Leu Ser Arg Ala
             20                  25                  30

Ser Gly Ala Ala Arg Phe Ser Val Ile Phe Leu Phe Phe Gly Ala Val
         35                  40                  45

Ile Ile Thr Ser Val Leu Leu Leu Phe Pro Arg Ala Gly Glu Phe Pro
     50                  55                  60

Ala Pro Glu Val Glu Val Lys Ile Val Asp Asp Phe Phe Ile Gly Arg
 65                  70                  75                  80

Tyr Val Leu Leu Ala Phe Leu Ser Ala Ile Phe Leu Gly Gly Leu Phe
                 85                  90                  95

Leu Val Leu Ile His Tyr Val Leu Glu Pro Ile Tyr Ala Lys Pro Leu
            100                 105                 110

His Ser Tyr 
        115



<210> 2099
<211> 297
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2099
Met Leu Val Ala Leu Val Val Asn Leu Ile Leu His Cys Pro Lys Phe
  1               5                  10                  15

Trp Pro Phe Ala Met Leu Gly Gly Cys Ile Trp Ala Thr Gly Asn Ile
             20                  25                  30

Ala Val Val Pro Ile Ile Lys Thr Ile Gly Leu Gly Leu Gly Ile Leu
         35                  40                  45

Ile Trp Gly Ser Phe Asn Ala Leu Thr Gly Trp Ala Ser Ser Arg Phe
     50                  55                  60

Gly Trp Phe Gly Leu Asp Ala Glu Glu Val Ser Asn Pro Leu Leu Asn
 65                  70                  75                  80

Tyr Ile Gly Ala Gly Leu Ser Val Arg Lys Cys Phe His Ile Leu Xaa
                 85                  90                  95

Ile Lys Ser Glu Ile Pro Asn Asn Thr Cys Ser Met Asp Thr Thr Pro
            100                 105                 110

Leu Ile Thr Glu His Val Ile Asn Thr Thr Gln Asp Pro Cys Ser Trp
        115                 120                 125

Val Asp Lys Leu Ser Thr Val His His Arg Ile Val Gly Cys Ser Leu
    130                 135                 140

Ala Val Ile Ser Gly Val Leu Tyr Gly Ser Thr Phe Val Pro Ile Ile
145                 150                 155                 160

Tyr Ile Lys Asp His Ser Lys Arg Asn Asp Ser Ile Tyr Ala Gly Ala
                165                 170                 175

Ser Gln Tyr Asp Leu Asp Tyr Val Phe Ala His Phe Ser Gly Ile Phe
            180                 185                 190

Leu Thr Ser Thr Val Tyr Phe Leu Ala Tyr Cys Ile Ala Met Lys Asn
        195                 200                 205

Ser Pro Lys Leu Tyr Pro Glu Ala Val Leu Pro Gly Phe Leu Ser Gly
    210                 215                 220

Val Leu Trp Ala Ile Ala Thr Cys Cys Trp Phe Ile Ala Asn His Ser
225                 230                 235                 240

Leu Ser Ala Val Val Ser Phe Pro Ile Ile Thr Ala Gly Pro Gly Phe
                245                 250                 255

Ile Ala Ala Met Trp Gly Ile Phe Met Phe Lys Glu Ile Lys Gly Leu
            260                 265                 270

Gln Asn Tyr Leu Leu Met Ile Leu Ala Phe Cys Ile Ile Leu Thr Gly
        275                 280                 285

Ala Leu Cys Thr Ala Phe Ser Lys Ile 
    290                 295



<210> 2100
<211> 161
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2100
Met Gly Phe Ala Ser Tyr Leu Leu His Pro Ser Leu Leu Pro Ser Ser
  1               5                  10                  15

Ser Ser Ser Ser Xaa Ser Ser Val Cys Leu Leu Ser Pro Leu Arg Gln
             20                  25                  30

Val Gly Pro Pro Cys Gln Pro Ser Pro Ala Pro Ile Cys Ser Ser Leu
         35                  40                  45

Ser Gly Trp Arg Arg Val Lys Glu Thr Glu Lys Arg Ala Pro Ser Leu
     50                  55                  60

Pro Pro Pro Pro Phe Pro Pro Asp Pro Ile Gln Val Leu Ser Gln Lys
 65                  70                  75                  80

Cys Arg Tyr Val Ile Met His Phe Thr Asp Glu Gly Arg Gly Arg Ser
                 85                  90                  95

Ala Gln Asn Pro Pro His Pro Pro Val Gln Thr Ser Gly Ser Pro Pro
            100                 105                 110

Gln Ala Ser Ser Ala His Trp Ala Thr Ala Ser Gln Gln Val Thr Glu
        115                 120                 125

Ala Asn Glu Gly Thr Val Ser Leu Pro Leu Leu Ser Ser Phe Leu Asp
    130                 135                 140

Leu Phe Phe Ala Phe Xaa Phe Ile Ser Leu Thr Arg Arg Ala Lys Leu
145                 150                 155                 160

Phe 




<210> 2101
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2101
Met Ala Glu Ser Glu Gly Asp Gly Glu Thr Arg Pro Ile Pro Ser Ala
  1               5                  10                  15

Ala Ser Phe Pro Pro Arg Pro Tyr Ser Gly Phe Lys Ser Lys Met Ser
             20                  25                  30

Ile Cys His Tyr Ala Leu Pro Gln Pro Glu Val Phe Phe Ser Phe Leu
         35                  40                  45

Leu Phe Tyr Tyr Phe Phe Leu Phe Leu Lys Ser Ser Asp Arg Gly Phe
     50                  55                  60

Leu Asp Ser Ser Trp Ala Leu Leu Pro Thr Ser Phe Thr Leu His Ser
 65                  70                  75                  80

Cys Pro Pro Leu Pro Pro Pro Pro Pro Pro Pro Ser Val Ser Phe His
                 85                  90                  95

Leu Cys Ala Arg Ser Val Leu Pro Ala Lys Leu Pro Pro Ser Gly Arg
            100                 105                 110

Ile Arg Gly Leu Gln Pro Gln Ala Ser Lys Arg Pro Thr Gly Ala Thr
        115                 120                 125

Ala Lys Pro Asn Lys Val Thr Arg Lys Pro Lys Arg Arg Gly Asp Xaa
    130                 135                 140

Phe Pro Leu Ser Asn Phe Leu Ile Leu Phe Phe Leu Glu Ser Phe Phe
145                 150                 155                 160

Leu His Phe Pro Xaa Ile Xaa Phe 
                165



<210> 2102
<211> 604
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (226)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (397)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2102
Met Pro Val Leu Pro Val Pro Leu Cys Xaa Phe Arg Phe Leu Pro Ala
  1               5                  10                  15

Leu His His Val Arg Leu Arg Arg Arg Val Phe Asn Ala Arg Leu Arg
             20                  25                  30

Arg Trp His Arg Leu Arg Ile Gln Ala Gly Gln Gly Pro Glu Tyr Leu
         35                  40                  45

Arg Tyr Ser Leu Cys Ile Leu Tyr Leu Phe Asp Val Gln Arg Val Ile
     50                  55                  60

Asn Gln Ile Leu Leu Leu Phe Leu Val Asn Gly His Ile Pro Tyr Arg
 65                  70                  75                  80

Arg Arg Gly Gly Gly Arg Ala Ala Cys Ile Thr Gln Arg Ser Pro Lys
                 85                  90                  95

Arg Asn His Phe Thr Glu Met Met Leu Ala Ala Val Pro Cys Ala Leu
            100                 105                 110

Val Glu Arg Leu Phe Leu Ala Pro Asp Lys Ile Leu Asp Val Ser Lys
        115                 120                 125

Leu Leu Gln His Phe Leu His Arg Phe Met Arg Glu Arg Val Glu Leu
    130                 135                 140

Leu Asp Thr His Asn Gly Asp Ile Val Leu Ile Val Leu Thr Thr Leu
145                 150                 155                 160

Phe Gln Gln Val Val Ile Asn Leu Thr Arg Thr His His Tyr Ala Leu
                165                 170                 175

Ser Arg Pro Ser Asp Gln Ala Arg Arg Phe His Arg Trp Leu Ala Gly
            180                 185                 190

Arg Cys Arg Ser Pro Val Leu Arg Gly Trp Lys Pro Pro Ala Asp Asp
        195                 200                 205

Ala Ala Gly Ile Ser Ala Thr Ser Arg Pro Ala Asp Asp Ala Ser Arg
    210                 215                 220

Ala Xaa Leu Thr Thr Gln His Val Val Asn Leu Cys Arg Gly Arg Arg
225                 230                 235                 240

Tyr Ala Asn Leu His Val Leu Leu Ser Thr Lys Leu Gln Ile Thr Phe
                245                 250                 255

Gln Thr Arg Gly Gly Val Leu Arg Pro Leu Pro Phe Val Thr Val Arg
            260                 265                 270

Gln Gln His His Gln Thr Thr His Pro Ala Pro Phe Leu Phe Ala Arg
        275                 280                 285

Gly Asp Glu Leu Val Asp Asn His Leu Arg Thr Val Gly Glu Val Thr
    290                 295                 300

Glu Leu Arg Phe Pro Asp Gly Gln Ser Ala Trp Phe Cys Gly Gly Ile
305                 310                 315                 320

Thr Ile Phe Lys Arg Gln His Cys Phe Phe Arg Gln Tyr Gly Val Pro
                325                 330                 335

Asp Thr Glu Arg Ala Leu Pro Val Met Asp Met Leu Gln Arg Arg Val
            340                 345                 350

Ser Gly Thr Val Arg Leu Val Val Asp His Arg Val Ala Val Glu Glu
        355                 360                 365

Gly Thr Ala Thr Gly Val Phe Thr Arg Gln Ala Asn Arg Asn Ala Phe
    370                 375                 380

Ile Asn Gln Arg Gly Val Ser Glu Val Phe Arg Thr Xaa Pro Val Glu
385                 390                 395                 400

Gln Phe Leu Thr Gly Ser His Arg Leu Ala Ile Ala Ile Asn Leu Gly
                405                 410                 415

Asn Ala Arg Leu His Phe Asn Cys Phe Arg His Arg Ala Asp Ala Phe
            420                 425                 430

Arg Gln Leu Leu Gln Ala Leu His Leu Asn Phe Val Arg Val Leu Phe
        435                 440                 445

Val Pro Phe Val Val Glu Val Arg Arg Pro Gly Glu Arg Val His Val
    450                 455                 460

His Arg Thr Pro Leu Cys His Tyr Ala Ile Ala Ser Ile Gln Arg Ile
465                 470                 475                 480

Ala Val Gln Val Asn His Leu Gly Gly Ile Phe Gln Arg Arg His Phe
                485                 490                 495

Phe Leu Leu Gln Leu Val Ser Val Asp Phe Ala Arg Cys Arg Met Phe
            500                 505                 510

Phe Asp Phe Leu Ile His Gln Arg Leu Gly Cys Ala Arg Leu Val Gly
        515                 520                 525

Phe Val Val Ala Val Thr Ala Val Ala His Gln Val Asp Glu Asp Ile
    530                 535                 540

Thr Phe Lys Gly Val Thr Glu Ile Glu Arg Gln Thr Gly His Lys Gly
545                 550                 555                 560

Asn Gly Phe Arg Ile Val Arg Val Asn Val Glu Asn Arg Gly Leu Asn
                565                 570                 575

His Leu Thr Asp Ile Ser Thr Val Arg Arg Arg Thr Gly Ile Gln Arg
            580                 585                 590

Ile Arg Gly Gly Glu Thr Asn Leu Val Val Asp Asn 
        595                 600



<210> 2103
<211> 241
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (203)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (219)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2103
Met Leu Leu Met Glu Phe Val Glu Gly Thr Xaa His Asp Val Asp Leu
  1               5                  10                  15

Val Leu Phe Gly Gly Arg Leu Leu Ala Ala Phe Val Ser Asp Asn Gly
             20                  25                  30

Pro Thr Arg Leu Pro Gly Phe Thr Glu Thr Ala Ala Cys Met Pro Thr
         35                  40                  45

Gly Leu Ala Pro Glu Gln Glu Ala Gln Met Val Gln Ala Ala Phe Arg
     50                  55                  60

Cys Cys Leu Gly Cys Gly Leu Leu Asp Gly Val Phe Asn Val Glu Leu
 65                  70                  75                  80

Lys Leu Thr Gly Ala Gly Pro Arg Leu Ile Glu Ile Asn Pro Arg Met
                 85                  90                  95

Gly Gly Phe Tyr Leu Arg Asp Trp Ile Leu Glu Leu Tyr Gly Val Asp
            100                 105                 110

Leu Leu Leu Ala Ala Val Met Val Ala Cys Gly Leu Arg Pro Ala Leu
        115                 120                 125

Pro Thr Arg Pro Arg Ala Arg Gly His Leu Val Gly Val Met Cys Leu
    130                 135                 140

Val Ser Gln His Leu Gln Ala Leu Ser Ser Thr Ala Ser Arg Glu Thr
145                 150                 155                 160

Leu Gln Ala Leu His Asp Arg Gly Leu Leu Arg Leu Asn Leu Leu Glu
                165                 170                 175

Glu Ala Leu Val Pro Gly Glu Tyr Glu Glu Pro Tyr Cys Ser Val Ala
            180                 185                 190

Cys Ala Gly Pro Ser Pro Thr Glu Ala Arg Xaa Arg Leu Leu Gly Leu
        195                 200                 205

Cys Gln Gly Leu Gly Ile Asp Gly Pro Ser Xaa Pro Val Ala His Phe
    210                 215                 220

Leu Ser Asn Ser Asn Asn Thr Gly Val Arg Xaa Gly Glu Ala Val Trp
225                 230                 235                 240

Val 




<210> 2104
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2104
Met Ser Thr Gly Leu Val Pro Val Glu Ala Pro Gly Gln Asn Leu Leu
  1               5                  10                  15

Leu Val Ser Phe Thr Ser Arg Gly Cys Gln His Ser Leu Ala Ser Gly
             20                  25                  30

Cys Val Thr Met Ile Ser Val Ser Met Ile Thr Leu Pro Ser Pro Leu
         35                  40                  45

Met Tyr Leu Asn Leu Leu Gln Phe Pro Ser Phe Phe Leu Asp Gly Val
     50                  55                  60

Ser Leu Leu Leu Pro Xaa Leu Gly Val Ala Met Ala Arg Ser Arg Ala
 65                  70                  75                  80

His Trp Thr Phe Cys Leu Pro Gly Ser Ser Asp Ser Ser Ala Ser Ala
                 85                  90                  95

Ser Tyr Met Gly Trp Gly Leu Arg Thr Leu Xaa His His Pro Gln 
            100                 105                 110



<210> 2105
<211> 174
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2105
Met Ala Glu Ala Glu Glu Ser Pro Gly Asp Pro Gly Thr Ala Ser Pro
  1               5                  10                  15

Arg Pro Leu Phe Ala Gly Leu Ser Asp Ile Ser Ile Ser Gln Asp Ile
             20                  25                  30

Pro Val Glu Gly Glu Ile Thr Ile Pro Met Arg Ser Arg Ile Arg Glu
         35                  40                  45

Phe Asp Ser Ser Thr Leu Asn Glu Ser Val Arg Asn Thr Ile Met Arg
     50                  55                  60

Asp Leu Lys Ala Val Gly Lys Lys Phe Met His Val Leu Tyr Pro Arg
 65                  70                  75                  80

Lys Ser Asn Thr Leu Leu Arg Asp Trp Asp Leu Trp Gly Pro Leu Ile
                 85                  90                  95

Leu Cys Val Thr Leu Ala Leu Met Leu Gln Arg Asp Ser Ala Asp Ser
            100                 105                 110

Glu Lys Asp Gly Gly Pro Gln Phe Ala Glu Val Phe Val Ile Val Trp
        115                 120                 125

Phe Gly Ala Val Thr Ile Thr Leu Asn Ser Lys Leu Leu Gly Gly Asn
    130                 135                 140

Ile Ser Phe Phe Gln Xaa Leu Cys Val Leu Gly Tyr Xaa Ile Leu Pro
145                 150                 155                 160

Leu Thr Val Ala Met Leu Ile Cys Arg Leu Val Leu Xaa Gly 
                165                 170



<210> 2106
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2106
Met Ile Leu Pro Glu Glu Gly Thr Asn Gly Cys Trp Ala Gly Gln Ser
  1               5                  10                  15

Ile Ser Cys Pro Val Gln Ala Ser Pro Leu Ser Leu Val Ser Ser Phe
             20                  25                  30

Ser Ser Val Ser Leu Leu Ser Leu Thr Leu Cys Pro Ile Ser His Tyr
         35                  40                  45

Ser Trp Ser Trp Glu Leu Pro Ser Glu Asp Thr Pro Leu Gly Val Pro
     50                  55                  60

Glu Pro Gly Leu Glu Gly Arg Gly Arg Ile Leu Pro Ser Gln Ser Gly
 65                  70                  75                  80

Cys Ser Ile Lys Asn His Leu Glu Met Val Phe Cys Leu Glu Leu Leu
                 85                  90                  95

Pro Phe Cys Phe Ile Ile Phe Pro Gln Met Ser 
            100                 105



<210> 2107
<211> 260
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2107
Met Pro Pro Thr Leu Gly Thr Asn Val Leu Gly Arg Lys Val Leu Tyr
  1               5                  10                  15

Leu Pro Ser Phe Phe Thr Tyr Ala Lys Tyr Ile Val Gln Val Asp Gly
             20                  25                  30

Lys Ile Gly Leu Phe Arg Gly Leu Ser Pro Arg Leu Met Ser Asn Ala
         35                  40                  45

Leu Ser Thr Val Thr Arg Gly Ser Met Lys Lys Val Phe Pro Pro Asp
     50                  55                  60

Glu Ile Glu Gln Val Ser Asn Lys Asp Xaa Met Lys Thr Ser Leu Lys
 65                  70                  75                  80

Lys Val Val Lys Glu Thr Ser Tyr Glu Met Met Met Gln Cys Val Ser
                 85                  90                  95

Arg Met Leu Ala His Pro Leu His Val Ile Ser Met Arg Cys Met Val
            100                 105                 110

Gln Phe Val Gly Arg Glu Ala Lys Tyr Ser Gly Val Leu Ser Ser Ile
        115                 120                 125

Gly Lys Ile Phe Lys Glu Glu Gly Leu Leu Gly Phe Phe Val Gly Leu
    130                 135                 140

Ile Pro His Leu Leu Gly Asp Val Val Phe Leu Trp Gly Cys Asn Leu
145                 150                 155                 160

Leu Ala His Phe Ile Asn Ala Tyr Leu Val Asp Asp Ser Phe Ser Gln
                165                 170                 175

Ala Leu Ala Ile Arg Ser Tyr Thr Lys Phe Val Met Gly Ile Ala Val
            180                 185                 190

Ser Met Leu Thr Tyr Pro Phe Leu Leu Val Gly Asp Leu Met Ala Val
        195                 200                 205

Asn Asn Cys Gly Leu Gln Ala Gly Leu Pro Pro Tyr Ser Pro Val Phe
    210                 215                 220

Lys Ser Trp Ile His Cys Trp Lys Tyr Leu Ser Val Gln Gly Gln Leu
225                 230                 235                 240

Phe Arg Gly Ser Ser Leu Leu Phe Arg Arg Val Ser Ser Gly Ser Cys
                245                 250                 255

Phe Ala Leu Glu 
            260



<210> 2108
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2108
Met Ala Gly Thr Gly Ser Met Leu Pro Cys Ser Gly Leu Cys Pro Ser
  1               5                  10                  15

Ala Pro Thr Xaa Pro Gly Phe Gly Leu Val Thr Arg Tyr Pro Val Arg
             20                  25                  30

Xaa Trp Leu Leu Gly Xaa Leu Leu Ser Gly Leu Ser Val Ala Ile Met
         35                  40                  45

Gln Leu Pro Gln Gly Leu Xaa Tyr Ala Leu Leu Ala Gly Leu Pro Pro
     50                  55                  60

Val Phe Gly Leu Tyr Ser Ser Phe Tyr Pro Val Phe Ile Tyr Phe Leu
 65                  70                  75                  80

Phe Gly Thr Ser Arg Gln Pro Cys Phe Gly His Gln Thr Leu Asn Met
                 85                  90                  95

Leu His Pro Ala Gln Asp Cys Thr Ser Gly Gly Ala Gly His Pro 
            100                 105                 110



<210> 2109
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2109
Met Ser Val Gly Leu Asp Leu Pro Gln Met Leu Pro Gly Ser Pro Ser
  1               5                  10                  15

Pro Ser Leu Lys Glu Ala Phe Ala Glu Asp Gly Glu Ala Gly Glu Gly
             20                  25                  30

Gly Gly Arg Pro Ser Leu Glu Trp Arg Leu Gln Gln Leu Leu Pro Gln
         35                  40                  45

His Pro Leu Ser Leu Ser Trp Leu Leu Thr Ser Pro Gln Ala Pro Xaa
     50                  55                  60

Pro Phe Leu Pro Ser Val Val Ile Cys His Leu Leu Asp Gln Val Leu
 65                  70                  75                  80

Ser Leu Leu His Ser Pro Val Pro Thr Pro Val His Ser Ser Gly Pro
                 85                  90                  95

Gly Gly Lys Gln Ala Val Asn Ser Trp Pro Glu Leu Ser Leu Trp Leu
            100                 105                 110

Val Ala His Ala Pro Phe Leu Val Val Cys 
        115                 120



<210> 2110
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2110
Met Trp Ala Gln Pro Cys Ala Arg Arg Leu Ala Gly Ile Lys Val Gln
  1               5                  10                  15

Ile Glu Ala Ser Pro Pro Leu Gly Pro Leu Ala Leu Arg Val Phe Ala
             20                  25                  30

Ala Ser Glu Pro Thr Cys Pro Gln Gly His Ser Cys Ile Ser Cys Pro
         35                  40                  45

Ala Val Ile Thr Gly Met Gly Arg Leu Ala Trp Gly Gln Pro Leu Pro
     50                  55                  60

Leu Pro Gly Cys Cys Cys Val Phe Leu Pro Ala Arg Gly His Cys Gln
 65                  70                  75                  80

Asp His Ala Ser Leu Phe Ile Ser Arg Phe Leu Ser Ser Ala Ile Val
                 85                  90                  95

Val Phe Trp Trp Arg Lys Lys Asn Arg Val Ala Val Phe Glu Leu Pro
            100                 105                 110

Gly Thr 




<210> 2111
<211> 247
<212> PRT
<213> Homo sapiens

<400> 2111
Met Leu Lys Pro Leu Gln Gln Pro Gly Leu Thr Trp Leu Gln Ser Pro
  1               5                  10                  15

Tyr Trp Ala Glu Arg Ser Arg Val Ala Pro Ala Glu Pro Gln Glu Ala
             20                  25                  30

Pro Asp Ser Thr Ala Ala Gly Gly Ser Ala Ser Lys Arg Met Ala Leu
         35                  40                  45

Val Leu Glu Arg Val Cys Ser Thr Leu Leu Gly Leu Glu Glu His Leu
     50                  55                  60

Asn Ala Leu Asp Arg Ala Ala Gly Asp Gly Asp Cys Gly Thr Thr His
 65                  70                  75                  80

Ser Arg Ala Ala Arg Ala Ile Gln Glu Trp Leu Lys Glu Gly Pro Pro
                 85                  90                  95

Pro Ala Ser Pro Ala Gln Leu Leu Ser Lys Leu Ser Val Leu Leu Leu
            100                 105                 110

Glu Lys Met Gly Gly Ser Ser Gly Ala Leu Tyr Gly Leu Phe Leu Thr
        115                 120                 125

Ala Ala Ala Gln Pro Leu Lys Ala Lys Thr Ser Leu Pro Ala Trp Ser
    130                 135                 140

Ala Ala Met Asp Ala Gly Leu Glu Ala Met Gln Lys Tyr Gly Lys Ala
145                 150                 155                 160

Ala Pro Gly Asp Arg Thr Met Leu Asp Ser Leu Trp Ala Ala Gly Gln
                165                 170                 175

Glu Leu Gln Ala Trp Lys Ser Pro Gly Ala Asp Leu Leu Gln Val Leu
            180                 185                 190

Thr Lys Ala Val Lys Ser Ala Glu Ala Ala Ala Glu Ala Thr Lys Asn
        195                 200                 205

Met Glu Ala Gly Ala Gly Arg Ala Ser Tyr Ile Ser Ser Ala Arg Leu
    210                 215                 220

Glu Gln Pro Asp Pro Gly Ala Val Ala Ala Ala Ala Ile Leu Arg Ala
225                 230                 235                 240

Ile Leu Glu Val Leu Gln Ser 
                245



<210> 2112
<211> 277
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2112
Met Lys Ile Trp Gln Ala Ser Asn Gly Glu Leu Arg Arg Val Leu Glu
  1               5                  10                  15

Gly His Val Phe Asp Val Asn Cys Cys Arg Phe Phe Pro Ser Gly Leu
             20                  25                  30

Val Val Leu Ser Gly Gly Met Asp Ala Gln Leu Lys Ile Trp Ser Ala
         35                  40                  45

Glu Asp Ala Ser Cys Val Val Thr Phe Lys Gly Xaa Lys Gly Gly Ile
     50                  55                  60

Leu Asp Thr Ala Ile Val Asp Arg Gly Arg Asn Val Val Ser Ala Ser
 65                  70                  75                  80

Arg Asp Gly Thr Ala Arg Leu Trp Asp Cys Gly Arg Ser Xaa Cys Leu
                 85                  90                  95

Gly Val Leu Ala Asp Cys Gly Ser Ser Ile Asn Gly Val Ala Val Gly
            100                 105                 110

Ala Ala Asp Asn Ser Ile Asn Leu Gly Ser Pro Glu Gln Met Pro Ser
        115                 120                 125

Glu Arg Glu Val Gly Thr Glu Ala Lys Met Leu Leu Leu Ala Arg Glu
    130                 135                 140

Asp Lys Lys Leu Gln Cys Leu Gly Leu Gln Ser Arg Gln Leu Val Phe
145                 150                 155                 160

Leu Phe Ile Gly Ser Asp Ala Phe Asn Cys Cys Thr Phe Leu Ser Gly
                165                 170                 175

Phe Leu Leu Leu Ala Gly Thr Gln Asp Gly Asn Ile Tyr Gln Leu Asp
            180                 185                 190

Val Arg Ser Pro Arg Ala Pro Val Gln Val Ile His Arg Ser Gly Ala
        195                 200                 205

Pro Val Leu Ser Leu Leu Ser Val Arg Asp Gly Phe Ile Ala Ser Gln
    210                 215                 220

Gly Asp Gly Ser Cys Phe Ile Val Gln Gln Asp Leu Asp Tyr Val Thr
225                 230                 235                 240

Glu Leu Thr Gly Ala Asp Cys Asp Pro Val Tyr Lys Val Ala Thr Trp
                245                 250                 255

Glu Lys Gln Ile Tyr Thr Cys Cys Arg Asp Gly Leu Val Arg Arg Tyr
            260                 265                 270

Gln Leu Ser Asp Leu 
        275



<210> 2113
<211> 139
<212> PRT
<213> Homo sapiens

<400> 2113
Met Glu Ala Val Val Phe Val Phe Ser Leu Leu Asp Cys Cys Ala Leu
  1               5                  10                  15

Ile Phe Leu Ser Val Tyr Phe Ile Ile Thr Leu Ser Asp Leu Glu Cys
             20                  25                  30

Asp Tyr Ile Asn Ala Arg Ser Cys Cys Ser Lys Leu Asn Lys Trp Val
         35                  40                  45

Ile Pro Glu Leu Ile Gly His Thr Ile Val Thr Val Leu Leu Leu Met
     50                  55                  60

Ser Leu His Trp Phe Ile Phe Leu Leu Asn Leu Pro Val Ala Thr Trp
 65                  70                  75                  80

Asn Ile Tyr Arg Tyr Ile Met Val Pro Ser Gly Asn Met Gly Val Phe
                 85                  90                  95

Asp Pro Thr Glu Ile His Asn Arg Gly Gln Leu Lys Ser His Met Lys
            100                 105                 110

Glu Ala Met Ile Lys Leu Gly Phe His Leu Leu Cys Phe Phe Met Tyr
        115                 120                 125

Leu Tyr Ser Met Ile Leu Ala Leu Ile Asn Asp 
    130                 135



<210> 2114
<211> 346
<212> PRT
<213> Homo sapiens

<400> 2114
Met Ala Pro Asn Ser Ile Thr Leu Leu Gly Leu Ala Val Asn Val Val
  1               5                  10                  15

Thr Thr Leu Val Leu Ile Ser Tyr Cys Pro Thr Ala Thr Glu Glu Ala
             20                  25                  30

Pro Tyr Trp Thr Tyr Leu Leu Cys Ala Leu Gly Leu Phe Ile Tyr Gln
         35                  40                  45

Ser Leu Asp Ala Ile Asp Gly Lys Gln Ala Arg Arg Thr Asn Ser Cys
     50                  55                  60

Ser Pro Leu Gly Glu Leu Phe Asp His Gly Cys Asp Ser Leu Ser Thr
 65                  70                  75                  80

Val Phe Met Ala Val Gly Ala Ser Ile Ala Ala Arg Leu Gly Thr Tyr
                 85                  90                  95

Pro Asp Trp Phe Phe Phe Cys Ser Phe Ile Gly Met Phe Val Phe Tyr
            100                 105                 110

Cys Ala His Trp Gln Thr Tyr Val Ser Gly Met Leu Arg Phe Gly Lys
        115                 120                 125

Val Asp Val Thr Glu Ile Gln Ile Ala Leu Val Ile Val Phe Val Leu
    130                 135                 140

Ser Ala Phe Gly Gly Ala Thr Met Trp Asp Tyr Thr Ile Pro Ile Leu
145                 150                 155                 160

Glu Ile Lys Leu Lys Ile Leu Pro Val Leu Gly Phe Leu Gly Gly Val
                165                 170                 175

Ile Phe Ser Cys Ser Asn Tyr Phe His Val Ile Leu His Gly Gly Val
            180                 185                 190

Gly Lys Asn Gly Ser Thr Ile Ala Gly Thr Ser Val Leu Ser Pro Gly
        195                 200                 205

Leu His Ile Gly Leu Ile Ile Ile Leu Ala Ile Met Ile Tyr Lys Lys
    210                 215                 220

Ser Ala Thr Asp Val Phe Glu Lys His Pro Cys Leu Tyr Ile Leu Met
225                 230                 235                 240

Phe Gly Cys Val Phe Ala Lys Val Ser Gln Lys Leu Val Val Ala His
                245                 250                 255

Met Thr Lys Ser Glu Leu Tyr Leu Gln Asp Thr Val Phe Leu Gly Pro
            260                 265                 270

Gly Leu Leu Phe Leu Asp Gln Tyr Phe Asn Asn Phe Ile Asp Glu Tyr
        275                 280                 285

Val Val Leu Trp Met Ala Met Val Ile Ser Ser Phe Asp Met Val Ile
    290                 295                 300

Tyr Phe Ser Ala Leu Cys Leu Gln Ile Ser Arg His Leu His Leu Asn
305                 310                 315                 320

Ile Phe Lys Thr Ala Cys His Gln Ala Pro Glu Gln Val Gln Val Leu
                325                 330                 335

Ser Ser Lys Ser His Gln Asn Asn Met Asp 
            340                 345



<210> 2115
<211> 193
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2115
Met Gly Ile Phe Ser His Ser Gln Phe Phe Asp Leu Met Leu Tyr Ser
  1               5                  10                  15

His Gly Gln Ile Glu Ile Asp Asp Gln Val Glu Gly Leu Gln Tyr Leu
             20                  25                  30

Ala Ser Arg Tyr Asp Phe Ile Asp Leu Xaa Arg Val Gly Ile His Gly
         35                  40                  45

Trp Ser Tyr Gly Gly Tyr Leu Ser Leu Met Ala Leu Met Gln Arg Ser
     50                  55                  60

Asp Ile Phe Arg Val Ala Ile Ala Gly Ala Pro Val Thr Leu Trp Ile
 65                  70                  75                  80

Phe Tyr Asp Thr Gly Tyr Thr Glu Arg Tyr Met Gly His Pro Asp Gln
                 85                  90                  95

Asn Glu Gln Gly Tyr Tyr Leu Gly Ser Val Ala Met Gln Ala Glu Lys
            100                 105                 110

Phe Pro Ser Glu Pro Asn Arg Leu Leu Leu Leu His Gly Phe Leu Asp
        115                 120                 125

Glu Asn Val His Phe Ala His Thr Ser Ile Leu Leu Ser Phe Leu Val
    130                 135                 140

Arg Ala Gly Lys Pro Tyr Asp Leu Gln Ile Tyr Pro Gln Glu Arg His
145                 150                 155                 160

Ser Ile Arg Val Pro Glu Ser Gly Glu His Tyr Glu Leu His Leu Leu
                165                 170                 175

His Tyr Leu Gln Glu Asn Leu Gly Ser Arg Ile Ala Ala Leu Lys Val
            180                 185                 190

Ile 




<210> 2116
<211> 286
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (266)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2116
Met Ala Met Glu Gly Tyr Trp Arg Phe Leu Ala Leu Leu Gly Ser Ala
  1               5                  10                  15

Leu Leu Val Gly Phe Leu Ser Val Xaa Phe Ala Leu Val Trp Val Leu
             20                  25                  30

His Tyr Arg Glu Gly Leu Gly Trp Asp Gly Ser Ala Leu Glu Phe Asn
         35                  40                  45

Trp His Pro Val Leu Met Val Thr Gly Phe Val Phe Ile Gln Gly Ile
     50                  55                  60

Ala Ile Ile Val Tyr Arg Leu Pro Trp Thr Trp Lys Cys Ser Lys Leu
 65                  70                  75                  80

Leu Met Lys Ser Ile His Ala Gly Leu Asn Ala Val Ala Ala Ile Leu
                 85                  90                  95

Ala Ile Ile Ser Val Val Ala Val Phe Glu Asn His Asn Val Asn Asn
            100                 105                 110

Ile Ala Asn Met Tyr Ser Leu His Ser Trp Val Gly Leu Ile Ala Val
        115                 120                 125

Ile Cys Tyr Leu Leu Gln Leu Leu Ser Gly Phe Ser Val Phe Leu Leu
    130                 135                 140

Pro Trp Ala Pro Leu Ser Leu Arg Ala Phe Leu Met Pro Ile His Val
145                 150                 155                 160

Tyr Ser Gly Ile Val Ile Phe Gly Thr Val Ile Ala Thr Ala Leu Met
                165                 170                 175

Gly Leu Thr Glu Lys Leu Ile Phe Ser Leu Arg Asp Pro Ala Tyr Ser
            180                 185                 190

Thr Phe Pro Pro Glu Gly Val Phe Val Asn Thr Leu Gly Leu Leu Ile
        195                 200                 205

Leu Val Phe Gly Ala Leu Ile Phe Trp Ile Val Thr Arg Pro Gln Trp
    210                 215                 220

Lys Arg Pro Lys Glu Pro Asn Ser Thr Ile Leu His Pro Asn Gly Gly
225                 230                 235                 240

Thr Glu Gln Gly Ala Arg Gly Ser Met Pro Ala Tyr Ser Gly Asn Asn
                245                 250                 255

Met Asp Lys Ser Asp Ser Glu Leu Asn Xaa Glu Val Ala Ala Arg Lys
            260                 265                 270

Arg Asn Leu Ala Leu Asp Glu Ala Gly Gln Arg Ser Thr Met 
        275                 280                 285



<210> 2117
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2117
Met Ser Pro Ala Gln Val Tyr Val Glu Gly Met Gly Ser Leu Gln Val
  1               5                  10                  15

Gly Gly Gly Xaa Ala Ser Gly Leu Val Val Ala Phe Asn Leu Leu His
             20                  25                  30

Trp Cys Phe Ser Asp Glu Arg Glu Ile His Ile Pro Leu Cys Leu Asn
         35                  40                  45

Phe Leu Ile Tyr Thr Gly Phe Lys Val Lys Thr Leu Phe Gln Glu Leu
     50                  55                  60

Thr Glu Ser Leu Gly Ser Phe Arg Thr Ser Ala Thr Leu Phe Ile Lys
 65                  70                  75                  80

Ile Leu Gly Ser Leu Pro Cys Ala Tyr Ser Val Val Gly Leu Leu Ala
                 85                  90                  95

Ser Arg Ser Gln Lys Arg Arg 
            100



<210> 2118
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2118
Met Gly Pro Trp Gly Glu Pro Glu Leu Leu Val Trp Arg Pro Glu Ala
  1               5                  10                  15

Val Ala Ser Glu Pro Pro Val Pro Val Gly Leu Glu Val Lys Leu Gly
             20                  25                  30

Ala Leu Val Leu Leu Leu Val Leu Thr Leu Leu Cys Xaa Leu Val Pro
         35                  40                  45

Ile Cys Val Leu Arg Arg Pro Xaa Ala Asn His Glu Xaa Ser Xaa Ser
     50                  55                  60

Arg Gln Lys Xaa Leu Xaa Leu Xaa Ser Cys Phe Ala Gly Gly Val Phe
 65                  70                  75                  80

Leu Ala Thr Cys Leu Leu Asp Leu Leu Pro Asp Tyr Leu Ala Xaa Ile
                 85                  90                  95

Asp Glu Ala Leu Ala Ala Leu Thr 
            100



<210> 2119
<211> 336
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2119
Met Val Ser Gln Cys Leu Phe Leu Phe Tyr Trp Pro Phe Cys Leu Pro
  1               5                  10                  15

Thr Ser Leu Gly Ile Val Asn Ile Gly Val Asn Asn Val Gln Glu Leu
             20                  25                  30

Ile Ile Ala Ala Asp Met Leu Gln Leu Thr Glu Val Val His Leu Cys
         35                  40                  45

Cys Glu Phe Leu Lys Gly Gln Ile Asp Pro Leu Asn Cys Ile Gly Ile
     50                  55                  60

Phe Gln Phe Ser Glu Gln Ile Ala Cys His Asp Leu Leu Glu Phe Ser
 65                  70                  75                  80

Glu Asn Tyr Ile His Val His Phe Leu Glu Val His Ser Gly Glu Glu
                 85                  90                  95

Phe Leu Ala Leu Thr Lys Asp Gln Leu Ile Lys Ile Leu Arg Ser Glu
            100                 105                 110

Glu Leu Ser Ile Glu Asp Glu Tyr Gln Val Phe Leu Ala Ala Met Gln
        115                 120                 125

Trp Ile Leu Lys Asp Leu Gly Lys Arg Arg Lys His Val Val Glu Val
    130                 135                 140

Leu Asp Pro Ile Arg Phe Pro Leu Leu Pro Pro Gln Arg Leu Leu Lys
145                 150                 155                 160

Tyr Ile Glu Gly Val Ser Asp Phe Asn Leu Arg Val Ala Leu Gln Thr
                165                 170                 175

Leu Leu Lys Glu Tyr Cys Glu Val Cys Xaa Ser Pro Lys Glu Asn Lys
            180                 185                 190

Phe Cys Ser Phe Leu Gln Thr Ser Lys Val Arg Pro Arg Lys Lys Ala
        195                 200                 205

Arg Lys Tyr Leu Tyr Ala Val Gly Gly Tyr Thr Arg Leu Gln Gly Gly
    210                 215                 220

Arg Trp Ser Asp Ser Arg Ala Leu Ser Cys Val Glu Arg Phe Asp Thr
225                 230                 235                 240

Phe Ser Gln Tyr Trp Thr Thr Val Ser Ser Leu His Gln Ala Arg Ser
                245                 250                 255

Gly Leu Gly Val Thr Val Leu Gly Gly Met Val Tyr Ala Ile Gly Gly
            260                 265                 270

Glu Lys Asp Ser Met Ile Phe Asp Cys Thr Glu Cys Tyr Asp Pro Val
        275                 280                 285

Thr Lys Gln Trp Thr Thr Val Ala Ser Met Asn His Pro Arg Cys Gly
    290                 295                 300

Leu Gly Val Cys Val Cys Tyr Gly Ala Ile Tyr Ala Leu Gly Gly Trp
305                 310                 315                 320

Val Gly Ala Glu Ile Gly Asn Thr Leu Asn Asp Leu Ile Leu Met Lys
                325                 330                 335






<210> 2120
<211> 239
<212> PRT
<213> Homo sapiens

<400> 2120
Met Gly Ser Arg Pro Arg Ile His Pro Leu Val Pro Gln Val Pro Gly
  1               5                  10                  15

Pro Val Thr Ala Ala Met Ala Thr Gly Leu Ala Val Asn Gly Lys Gly
             20                  25                  30

Thr Ser Pro Phe Met Asp Ala Leu Thr Ala Asn Gly Thr Thr Asn Ile
         35                  40                  45

Gln Thr Ser Val Thr Gly Val Thr Ala Ser Lys Arg Lys Phe Ile Asp
     50                  55                  60

Asp Arg Arg Asp Gln Pro Phe Asp Lys Arg Leu Arg Phe Ser Val Arg
 65                  70                  75                  80

Gln Thr Glu Ser Ala Tyr Arg Tyr Arg Asp Ile Val Val Arg Lys Gln
                 85                  90                  95

Asp Gly Phe Thr His Ile Leu Leu Ser Thr Lys Ser Ser Glu Asn Asn
            100                 105                 110

Ser Leu Asn Pro Glu Val Met Arg Glu Val Gln Ser Ala Leu Ser Thr
        115                 120                 125

Ala Ala Ala Asp Asp Ser Lys Leu Val Leu Leu Ser Ala Val Gly Ser
    130                 135                 140

Val Phe Cys Cys Gly Leu Asp Phe Ile Tyr Phe Ile Arg Arg Leu Thr
145                 150                 155                 160

Asp Asp Arg Lys Arg Glu Ser Thr Lys Met Ala Glu Ala Ile Arg Asn
                165                 170                 175

Phe Val Asn Thr Phe Ile Gln Phe Lys Lys Pro Ile Ile Val Ala Val
            180                 185                 190

Asn Gly Pro Ala Ile Gly Leu Gly Ala Ser Ile Leu Pro Leu Cys Asp
        195                 200                 205

Val Val Trp Ala Asn Glu Lys Ala Trp Phe Gln Thr Pro Tyr Thr Thr
    210                 215                 220

Phe Gly Gln Ser Gln Met Ala Val Leu Pro Leu Cys Phe Pro Arg 
225                 230                 235



<210> 2121
<211> 108
<212> PRT
<213> Homo sapiens

<400> 2121
Met Ile Asp Lys Asn Gln Thr Cys Gly Val Gly Gln Asp Ser Val Pro
  1               5                  10                  15

Tyr Met Ile Cys Leu Ile His Ile Leu Glu Glu Trp Phe Gly Val Glu
             20                  25                  30

Gln Leu Glu Asp Tyr Leu Asn Phe Ala Asn Tyr Leu Leu Trp Val Phe
         35                  40                  45

Thr Pro Leu Ile Leu Leu Ile Leu Pro Tyr Phe Thr Ile Phe Leu Leu
     50                  55                  60

Tyr Leu Thr Ile Ile Phe Leu His Ile Tyr Lys Arg Lys Asn Val Leu
 65                  70                  75                  80

Lys Glu Ala Thr Leu Ile Ile Tyr Gly Met Val Gln Gly Lys Gln Trp
                 85                  90                  95

Gln Leu Cys Gly Met Asp Met Gln Pro Phe Gly Trp 
            100                 105



<210> 2122
<211> 151
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2122
Met Ala Ser Met Gln Lys Arg Leu Gln Lys Glu Leu Leu Ala Leu Gln
  1               5                  10                  15

Asn Asp Pro Pro Pro Gly Met Thr Leu Asn Glu Lys Ser Val Gln Asn
             20                  25                  30

Ser Ile Thr Gln Trp Ile Val Asp Met Glu Gly Ala Pro Gly Thr Leu
         35                  40                  45

Tyr Glu Gly Glu Lys Phe Gln Leu Leu Phe Lys Phe Ser Ser Arg Tyr
     50                  55                  60

Pro Phe Asp Ser Pro Gln Val Met Phe Thr Gly Glu Asn Ile Pro Val
 65                  70                  75                  80

His Pro His Val Tyr Ser Asn Gly His Ile Cys Leu Ser Ile Leu Thr
                 85                  90                  95

Glu Asp Trp Ser Pro Ala Leu Ser Val Gln Ser Val Cys Leu Ser Ile
            100                 105                 110

Ile Ser Met Leu Ser Ser Cys Lys Glu Lys Arg Arg Pro Pro Asp Asn
        115                 120                 125

Ser Phe Tyr Val Arg Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp
    130                 135                 140

Trp Tyr His Asp Asp Thr Xaa 
145                 150



<210> 2123
<211> 172
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2123
Met Leu Val His Leu Phe Arg Val Gly Ile Arg Gly Gly Pro Phe Pro
  1               5                  10                  15

Gly Arg Leu Leu Pro Pro Leu Arg Phe Gln Thr Phe Ser Ala Val Arg
             20                  25                  30

Tyr Ser Asp Gly Tyr Arg Ser Ser Ser Leu Leu Arg Ala Val Ala His
         35                  40                  45

Leu Arg Ser Gln Leu Trp Ala His Leu Pro Arg Ala Pro Leu Ala Pro
     50                  55                  60

Arg Trp Ser Pro Ser Ala Trp Cys Trp Val Gly Gly Ala Leu Leu Gly
 65                  70                  75                  80

Pro Met Val Leu Ser Lys His Pro His Leu Cys Leu Val Ala Leu Cys
                 85                  90                  95

Glu Ala Glu Glu Ala Pro Pro Ala Ser Ser Thr Thr His Val Val Gly
            100                 105                 110

Ser Arg Phe Asn Trp Lys Leu Phe Trp Gln Phe Leu His Pro Gln Leu
        115                 120                 125

Leu Val Leu Gly Val Xaa Val Val Leu Ala Leu Gly Ala Ala Leu Val
    130                 135                 140

Asn Val Gln Ile Pro Leu Ser Trp Ala Asn Leu Val Xaa Val Val Gly
145                 150                 155                 160

Gln Val His Lys Gly Pro Arg Lys Gly Val His Asp 
                165                 170



<210> 2124
<211> 161
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (149)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2124
Met Pro Leu Ser Pro Tyr Arg Tyr Ser Asp Gly Tyr Arg Ser Ser Ser
  1               5                  10                  15

Leu Leu Arg Ala Val Ala His Leu Arg Ser Gln Leu Trp Ala His Leu
             20                  25                  30

Pro Arg Ala Pro Leu Ala Pro Arg Trp Ser Pro Ser Ala Trp Cys Trp
         35                  40                  45

Val Gly Gly Xaa Leu Leu Gly Pro Met Val Leu Ser Lys His Pro His
     50                  55                  60

Leu Cys Leu Val Ala Leu Cys Glu Ala Glu Xaa Ala Pro Pro Ala Ser
 65                  70                  75                  80

Ser Thr Pro His Val Val Gly Ser Arg Phe Asn Trp Lys Leu Phe Trp
                 85                  90                  95

Gln Phe Leu His Pro His Leu Leu Val Leu Gly Val Ala Val Val Leu
            100                 105                 110

Ala Leu Gly Ala Ala Leu Val Glu Cys Tyr Arg Ser Pro Trp Phe Leu
        115                 120                 125

Gly Pro Xaa Gly Lys Ser Ser Gly Pro Ile Thr Gln Gly Xaa Thr Lys
    130                 135                 140

Gly Phe Ser Trp Xaa Asp Ser Gln Asn Phe Ser Asn His Trp Phe Ile
145                 150                 155                 160

Pro 




<210> 2125
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2125
Met Arg Glu Arg Gly Leu Gly Pro Leu Gly Val Phe Arg Ser Asp Ala
  1               5                  10                  15

Gly Leu Lys Ser Leu Pro Glu Gly Arg Arg Glu Ser Gly Ala Leu Glu
             20                  25                  30

Glu Cys Val Ile His Thr Gln Arg Val Cys Asp Trp Lys Val Pro Glu
         35                  40                  45

His Pro Leu Ala Pro Leu Leu Leu Leu Ser Phe Ala Val Leu Arg Ile
     50                  55                  60

Leu Ala Lys Pro Leu Pro Thr His Glu Ser Cys Ser Phe Ser Ser Pro
 65                  70                  75                  80

Gly Leu Pro Ser Leu Thr Asn Ile Ser Leu Ser Ala Asp Ser Ser Phe
                 85                  90                  95

Leu Pro Ser Asn Ala Ser Pro Cys Tyr Leu Gln Pro Gly Asn Phe Ser
            100                 105                 110

Asn Glu 




<210> 2126
<211> 425
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (261)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2126
Met Leu Lys His Gln Cys Ser Cys Gly Asp Asn Ser Arg His Pro Glu
  1               5                  10                  15

His Ala Gly Arg Ile Gln Ser Ile Trp Ser Arg Leu Gln Glu Arg Gly
             20                  25                  30

Leu Arg Ser Gln Cys Glu Cys Leu Arg Gly Arg Lys Ala Ser Leu Glu
         35                  40                  45

Glu Leu Gln Ser Val His Ser Glu Arg His Val Leu Leu Tyr Gly Thr
     50                  55                  60

Asn Pro Leu Ser Arg Leu Lys Leu Asp Asn Gly Lys Leu Ala Gly Leu
 65                  70                  75                  80

Leu Ala Gln Arg Met Phe Val Met Leu Pro Cys Gly Gly Val Gly Val
                 85                  90                  95

Asp Thr Asp Thr Ile Trp Asn Glu Leu His Ser Ser Asn Ala Ala Arg
            100                 105                 110

Trp Ala Ala Gly Ser Val Thr Asp Leu Ala Phe Lys Val Ala Ser Arg
        115                 120                 125

Glu Leu Lys Asn Gly Phe Ala Val Val Arg Pro Pro Gly His His Ala
    130                 135                 140

Asp His Ser Thr Ala Met Gly Phe Cys Phe Phe Asn Ser Val Ala Ile
145                 150                 155                 160

Ala Cys Arg Gln Leu Gln Gln Gln Ser Lys Ala Ser Lys Ile Leu Ile
                165                 170                 175

Val Asp Trp Asp Val His His Gly Asn Gly Thr Gln Gln Thr Phe Tyr
            180                 185                 190

Gln Asp Pro Ser Val Leu Tyr Ile Ser Leu His Arg His Asp Asp Gly
        195                 200                 205

Asn Phe Phe Pro Gly Ser Gly Ala Val Asp Glu Val Gly Ala Gly Ser
    210                 215                 220

Gly Glu Gly Phe Asn Val Asn Val Ala Trp Ala Gly Gly Leu Asp Pro
225                 230                 235                 240

Pro Met Gly Asp Pro Glu Tyr Leu Ala Ala Phe Arg Ile Val Val Met
                245                 250                 255

Pro Ile Ala Arg Xaa Phe Ser Pro Asp Leu Val Leu Val Ser Ala Gly
            260                 265                 270

Phe Asp Ala Ala Glu Gly His Pro Ala Pro Leu Gly Gly Tyr His Val
        275                 280                 285

Ser Ala Lys Cys Phe Gly Tyr Met Thr Gln Gln Leu Met Asn Leu Ala
    290                 295                 300

Gly Gly Ala Val Val Leu Ala Leu Glu Gly Gly His Asp Leu Thr Ala
305                 310                 315                 320

Ile Cys Asp Ala Ser Glu Ala Cys Val Ala Ala Leu Leu Gly Asn Arg
                325                 330                 335

Val Asp Pro Leu Ser Glu Glu Gly Trp Lys Gln Lys Pro Asn Leu Asn
            340                 345                 350

Ala Ile Arg Ser Leu Glu Ala Val Ile Arg Val His Ser Lys Tyr Trp
        355                 360                 365

Gly Cys Met Gln Arg Leu Ala Ser Cys Pro Asp Ser Trp Val Pro Arg
    370                 375                 380

Val Pro Gly Ala Asp Lys Glu Glu Val Glu Ala Val Thr Ala Leu Ala
385                 390                 395                 400

Ser Leu Ser Val Gly Ile Leu Ala Glu Asp Arg Pro Ser Glu Gln Leu
                405                 410                 415

Val Glu Glu Glu Glu Pro Met Asn Leu 
            420                 425



<210> 2127
<211> 258
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (180)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2127
Met Pro Arg Pro Arg Arg Val Ser Gln Leu Leu Asp Leu Cys Leu Trp
  1               5                  10                  15

Cys Phe Met Lys Asn Ile Ser Arg Tyr Leu Thr Asp Ile Lys Pro Leu
             20                  25                  30

Pro Pro Asn Ile Lys Asp Arg Leu Ile Lys Ile Met Ser Met Gln Gly
         35                  40                  45

Gln Ile Thr Asp Ser Asn Ile Ser Glu Ile Leu His Pro Glu Val Gln
     50                  55                  60

Thr Leu Asp Leu Arg Ser Cys Asp Ile Ser Asp Ala Ala Leu Leu His
 65                  70                  75                  80

Leu Ser Asn Cys Arg Lys Leu Lys Lys Leu Asn Leu Asn Ala Ser Lys
                 85                  90                  95

Gly Asn Arg Val Ser Val Thr Ser Glu Gly Ile Lys Ala Val Ala Ser
            100                 105                 110

Ser Cys Ser Tyr Leu His Glu Ala Ser Leu Lys Arg Cys Cys Asn Leu
        115                 120                 125

Thr Asp Glu Gly Val Val Ala Leu Ala Leu Asn Cys Gln Leu Leu Lys
    130                 135                 140

Ile Ile Asp Leu Gly Gly Cys Leu Ser Ile Thr Asp Val Ser Leu His
145                 150                 155                 160

Ala Leu Gly Lys Asn Cys Pro Phe Leu Gln Cys Val Asp Phe Ser Ala
                165                 170                 175

Thr Gln Val Xaa Asp Ser Gly Val Ile Ala Leu Val Ser Gly Pro Cys
            180                 185                 190

Ala Lys Lys Leu Glu Glu Ile His Met Gly His Cys Val Asn Leu Thr
        195                 200                 205

Asp Gly Ala Val Glu Ala Val Leu Thr Tyr Cys Pro Gln Ile Arg Ile
    210                 215                 220

Leu Leu Phe His Gly Cys Pro Leu Ile Thr Asp His Ser Arg Glu Val
225                 230                 235                 240

Leu Glu Gln Leu Val Gly Pro Asn Lys Leu Lys Gln Val Thr Trp Thr
                245                 250                 255

Val Tyr 




<210> 2128
<211> 329
<212> PRT
<213> Homo sapiens

<400> 2128
Met Asp Gly Pro Val Ala Glu His Ala Lys Gln Glu Pro Phe His Val
  1               5                  10                  15

Val Thr Pro Leu Leu Glu Ser Trp Ala Leu Ser Gln Val Ala Gly Met
             20                  25                  30

Pro Val Phe Leu Lys Cys Glu Asn Val Gln Pro Ser Gly Ser Phe Lys
         35                  40                  45

Ile Arg Gly Ile Gly His Phe Cys Gln Glu Met Ala Lys Lys Gly Cys
     50                  55                  60

Arg His Leu Val Cys Ser Ser Gly Gly Asn Ala Gly Ile Ala Ala Ala
 65                  70                  75                  80

Tyr Ala Ala Arg Lys Leu Gly Ile Pro Ala Thr Ile Val Leu Pro Glu
                 85                  90                  95

Ser Thr Ser Leu Gln Val Val Gln Arg Leu Gln Gly Glu Gly Ala Glu
            100                 105                 110

Val Gln Leu Thr Gly Lys Val Trp Asp Glu Ala Asn Leu Arg Ala Gln
        115                 120                 125

Glu Leu Ala Lys Arg Asp Gly Trp Glu Asn Val Pro Pro Phe Asp His
    130                 135                 140

Pro Leu Ile Trp Lys Gly His Ala Ser Leu Val Gln Glu Leu Lys Ala
145                 150                 155                 160

Val Leu Arg Thr Pro Pro Gly Ala Leu Val Leu Ala Val Gly Gly Gly
                165                 170                 175

Gly Leu Leu Ala Gly Val Val Ala Gly Leu Leu Glu Val Gly Trp Gln
            180                 185                 190

His Val Pro Ile Ile Ala Met Glu Thr His Gly Ala His Cys Phe Asn
        195                 200                 205

Ala Ala Ile Thr Ala Gly Lys Leu Val Thr Leu Pro Asp Ile Thr Ser
    210                 215                 220

Val Ala Lys Ser Leu Gly Ala Lys Thr Val Ala Ala Arg Ala Leu Glu
225                 230                 235                 240

Cys Met Gln Val Cys Lys Ile His Ser Glu Val Val Glu Asp Thr Glu
                245                 250                 255

Ala Val Ser Ala Val Gln Gln Leu Leu Asp Asp Glu Arg Met Leu Val
            260                 265                 270

Glu Pro Ala Cys Gly Ala Ala Leu Ala Ala Ile Tyr Ser Gly Leu Leu
        275                 280                 285

Arg Arg Leu Gln Ala Glu Gly Cys Leu Pro Pro Ser Leu Thr Ser Val
    290                 295                 300

Val Val Ile Val Cys Gly Gly Asn Asn Ile Asn Ser Arg Glu Leu Gln
305                 310                 315                 320

Ala Leu Lys Thr His Leu Gly Gln Val 
                325



<210> 2129
<211> 110
<212> PRT
<213> Homo sapiens

<400> 2129
Met Ala Ala Pro Arg Arg Gly Arg Gly Ser Ser Thr Val Leu Ser Ser
  1               5                  10                  15

Val Pro Leu Gln Met Leu Phe Tyr Leu Ser Gly Thr Tyr Tyr Ala Leu
             20                  25                  30

Tyr Phe Leu Ala Thr Leu Leu Met Ile Thr Tyr Lys Ser Gln Val Phe
         35                  40                  45

Ser Tyr Pro His Arg Tyr Leu Val Leu Asp Leu Ala Leu Leu Phe Leu
     50                  55                  60

Met Gly Ile Leu Glu Ala Val Arg Leu Tyr Leu Gly Thr Arg Gly Asn
 65                  70                  75                  80

Leu Thr Glu Ala Glu Arg Pro Leu Ala Ala Ser Leu Ala Leu Thr Ala
                 85                  90                  95

Gly Thr Ala Ser Ser Leu Pro Thr Ser Cys Phe Gly Arg Pro 
            100                 105                 110



<210> 2130
<211> 169
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (164)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2130
Met Xaa Leu Gly Ile Ile Ile Leu Lys Lys Arg Tyr Ser Ile Phe Lys
  1               5                  10                  15

Tyr Thr Ser Ile Ala Leu Val Ser Val Gly Ile Phe Ile Cys Thr Phe
             20                  25                  30

Met Ser Ala Lys Gln Val Thr Ser Gln Ser Ser Leu Ser Glu Asn Asp
         35                  40                  45

Gly Phe Gln Ala Phe Val Trp Trp Leu Leu Gly Ile Gly Ala Leu Thr
     50                  55                  60

Phe Ala Leu Leu Met Ser Ala Arg Met Gly Ile Phe Gln Glu Thr Leu
 65                  70                  75                  80

Tyr Lys Arg Phe Gly Lys His Ser Lys Glu Ala Leu Phe Tyr Asn His
                 85                  90                  95

Ala Leu Pro Leu Pro Gly Phe Val Phe Leu Ala Ser Asp Ile Tyr Asp
            100                 105                 110

His Ala Val Leu Phe Asn Lys Ser Glu Leu Tyr Glu Ile Pro Val Ile
        115                 120                 125

Gly Val Thr Leu Pro Ile Met Trp Phe Tyr Leu Leu Met Asn Ile Ile
    130                 135                 140

Thr Gln Tyr Val Cys Ile Arg Gly Val Phe Ile Leu Thr Thr Gly Met
145                 150                 155                 160

Arg Leu Pro Xaa Arg His Ala Arg Ser 
                165



<210> 2131
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2131
Met Ala Ser Leu Pro Gln Leu Met Ala Ala Pro Thr Ser Ser Cys Thr
  1               5                  10                  15

Ser Leu Ser Glu Ser Ala Ala Gly Leu Gly Gly Leu Ala Gly Val Gly
             20                  25                  30

Ala Ser Leu Ala Leu Trp Arg Trp Gly Trp Cys Val Thr Leu Met Gly
         35                  40                  45

Ala Val Cys Glu Asp Glu Trp Leu Gly Leu Cys Asp Ser Ala Cys Gly
     50                  55                  60

Trp Cys Xaa Xaa Cys Ala Pro Val Cys Val Leu Gly Xaa Gly Cys Glu
 65                  70                  75                  80

Thr Leu Arg Ser Cys Val Gly Gly Cys Glu Ala Gly Gly Asp Thr Val
                 85                  90                  95

Leu Val Ile Val Pro Gly Cys Val Phe Val Xaa Trp Val Cys Lys Val
            100                 105                 110

Leu Cys Val Leu Gly Leu 
        115



<210> 2132
<211> 225
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2132
Met Ala Glu Gly Glu Thr Glu Ser Pro Gly Pro Lys Lys Cys Gly Pro
  1               5                  10                  15

Tyr Ile Ser Ser Val Thr Ser Gln Ser Val Asn Leu Met Ile Arg Gly
             20                  25                  30

Xaa Val Leu Phe Phe Ile Gly Val Phe Leu Ala Leu Val Leu Asn Leu
         35                  40                  45

Leu Gln Ile Gln Arg Asn Val Thr Leu Phe Pro Pro Asp Val Ile Ala
     50                  55                  60

Ser Ile Phe Ser Ser Ala Trp Trp Val Pro Pro Cys Cys Gly Thr Ala
 65                  70                  75                  80

Ser Ala Val Ile Gly Leu Leu Tyr Pro Cys Ile Asp Arg His Leu Gly
                 85                  90                  95

Glu Pro His Lys Phe Lys Arg Glu Trp Ser Ser Val Met Arg Cys Val
            100                 105                 110

Ala Val Phe Val Gly Ile Asn His Ala Ser Ala Lys Val Asp Phe Asp
        115                 120                 125

Asn Asn Ile Gln Leu Ser Leu Thr Leu Ala Ala Leu Ser Ile Gly Leu
    130                 135                 140

Trp Trp Thr Phe Asp Arg Ser Arg Ser Gly Phe Gly Leu Gly Val Gly
145                 150                 155                 160

Ile Ala Phe Leu Ala Thr Val Val Thr Gln Leu Leu Val Tyr Asn Gly
                165                 170                 175

Val Tyr Gln Tyr Thr Ser Pro Asp Phe Leu Tyr Val Arg Ser Trp Leu
            180                 185                 190

Pro Cys Ile Phe Phe Ala Gly Gly Ile Thr Met Gly Asn Ile Gly Arg
        195                 200                 205

Gln Leu Ala Met Tyr Glu Cys Lys Val Ile Ala Glu Lys Ser His Gln
    210                 215                 220

Glu 
225



<210> 2133
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2133
Met Gly Cys Pro Ile Gly Lys Ala Gln Leu Lys Asn Arg Met Glu Gly
  1               5                  10                  15

Ser Gly Arg Arg Gln Leu Thr Gly Glu Pro Thr Phe Leu Thr Gln Val
             20                  25                  30

Pro Lys Glu Ser Asp Ala Asn Thr Pro Ser Ala Leu Ser Ile Ala Phe
         35                  40                  45

Ile Tyr Ser Leu Leu Arg Val Leu Ser Pro Phe Gly Glu Gly Ser Ser
     50                  55                  60

Pro Gly Thr Val Gly Ser Ala Cys Ser Pro Leu Gly Tyr Ile Leu Gly
 65                  70                  75                  80

Leu Xaa Ser Xaa His Tyr Ser Trp Arg Val Gln Ser Phe Thr Ser Ile
                 85                  90                  95

Cys Lys Cys Pro 
            100



<210> 2134
<211> 314
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (262)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2134
Met Asn Leu Glu Gly Ser Ile Gln Asp Leu Phe Glu Leu Phe Ser Ser
  1               5                  10                  15

Asn Glu Asn Gln Pro Leu Thr Thr Lys Val Cys Val Val Pro Ser Gln
             20                  25                  30

Pro Val Val Glu Leu Val Leu Met Lys Val Leu Gly Ala Cys Lys Leu
         35                  40                  45

Leu Leu Arg Leu Leu Asp Cys Cys Cys Lys Thr Phe Leu Leu Thr Val
     50                  55                  60

Lys His Leu Gly Leu Gln Glu Phe Ile Ile Leu Asn Leu Val Met Val
 65                  70                  75                  80

Gly Leu Val Ser Arg Leu Trp Val Leu Tyr Lys Gly Val Leu Lys Arg
                 85                  90                  95

Leu Ile Leu Leu Tyr Glu Pro Leu Phe Gly Leu Leu Gln Glu Val Ala
            100                 105                 110

Arg Ile Gln Pro Met Pro Tyr Phe Lys Asp Phe Thr Phe Pro Ser Asp
        115                 120                 125

Ile Thr Glu Phe Leu Gly Gln Pro Tyr Phe Glu Ala Phe Lys Lys Lys
    130                 135                 140

Met Pro Ile Ala Phe Ala Ala Lys Gly Ile Asn Lys Leu Leu Asn Lys
145                 150                 155                 160

Leu Phe Leu Ile Asn Glu Gln Ser Pro Arg Ala Ser Glu Glu Thr Leu
                165                 170                 175

Leu Gly Ile Ser Lys Lys Ala Lys Gln Met Lys Ile Asn Val Gln Asn
            180                 185                 190

Asn Val Xaa Leu Gly Gln Pro Val Lys Asn Lys Arg Val Phe Lys Glu
        195                 200                 205

Glu Ser Ser Glu Phe Asp Val Arg Ala Phe Cys Asn Gln Leu Lys His
    210                 215                 220

Lys Ala Thr Gln Glu Thr Ser Phe Asp Phe Lys Cys Ser Gln Ser Arg
225                 230                 235                 240

Leu Lys Thr Thr Lys Tyr Ser Ser Gln Lys Val Ile Gly Thr Pro His
                245                 250                 255

Ala Lys Ser Ile Val Xaa Arg Phe Arg Glu Ala Glu Ser Phe Thr Gln
            260                 265                 270

Leu Ser Glu Glu Ile Gln Met Ala Val Val Trp Cys Arg Ser Lys Lys
        275                 280                 285

Leu Lys Ala Gln Ala Ile Phe Leu Gly Asn Lys Leu Leu Lys Ser Asn
    290                 295                 300

Arg Leu Lys His Leu Gly Ser Ser Arg Tyr 
305                 310



<210> 2135
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2135
Met Phe Gly Ala Met Ser Leu Tyr Gly Tyr Thr Thr Lys Arg Asp Leu
  1               5                  10                  15

Ser Gly Phe Gly Asn Met Leu Phe Met Ala Leu Ile Gly Ile Val Leu
             20                  25                  30

Ala Ser Leu Val Asn Phe Trp Leu Lys Ser Glu Ala Leu Met Trp Ala
         35                  40                  45

Val Thr Tyr Ile Gly Val Ile Val Phe Val Gly Leu Thr Ala Tyr Asp
     50                  55                  60

Thr Gln Lys Leu Lys Asn Met Gly Glu Gln Ile Asp Thr Arg Asp Thr
 65                  70                  75                  80

Ser Asn Leu Arg Lys Tyr Ser Ile Leu Gly Ala Leu Thr Leu Tyr Leu
                 85                  90                  95

Asp Phe Ile Asn Leu Phe Leu Met Leu Leu Arg Ile Xaa Gly Asn Arg
            100                 105                 110

Arg 




<210> 2136
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2136
Met Leu Pro Leu Leu Ala Arg Leu Cys Leu Val Pro Leu Glu Thr Ile
  1               5                  10                  15

Val Ile Ile Asn Lys Phe Ala Met Ile Phe Thr Gly Leu Glu Val Leu
             20                  25                  30

Tyr Phe Leu Gly Ser Asn Leu Leu Val Pro Tyr Asn Leu Ala Lys Ser
         35                  40                  45

Ala Tyr Arg Glu Leu Val Gln Val Val Glu Val Tyr Gly Leu Leu Ala
     50                  55                  60

Leu Gly Met Ser Leu Trp Asn Gln Leu Val Val Pro Val Leu Phe Met
 65                  70                  75                  80

Val Phe Trp Leu Val Leu Phe Ala Leu Gln Ile Tyr Ser Tyr Phe Ser
                 85                  90                  95

Thr Arg Asp Gln Pro Ala Ser Arg Glu Arg Leu Leu Phe Leu Phe Leu
            100                 105                 110

Thr Arg 




<210> 2137
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2137
Met Leu Ala Leu Pro Arg Ser Leu Thr Pro Pro Gly Cys Thr Trp Val
  1               5                  10                  15

Gly Met Val Ala Ser Met Pro Leu Cys Leu Leu Lys Asp Leu Leu Leu
             20                  25                  30

Leu Leu Ser Phe His Pro Ser Leu Ala Asp Asp Pro Glu Pro Ser Asp
         35                  40                  45

Asp Gly Ile Leu Leu Ala Arg Glu Lys Asp Leu Thr Arg Leu Leu Asn
     50                  55                  60

Leu Asn Ser Phe Arg Leu Tyr Phe Asn Phe Phe Phe Phe Val Gln Val
 65                  70                  75                  80

Leu Ile Leu Ile His Phe Asn Met Leu Leu Ser Lys Lys Lys Lys Lys
                 85                  90                  95

Lys Gly Xaa Arg Ser Arg Gly Ser Leu Glu Gly Pro Lys Leu Thr Arg
            100                 105                 110

Ala Cys Xaa Val Ile Ala Leu Xaa 
        115                 120



<210> 2138
<211> 206
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (181)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (183)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (184)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (198)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (201)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (206)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2138
Met Pro Asp Pro His Asn Leu Pro Ile Val Ala Gly Trp Lys Lys Tyr
  1               5                  10                  15

Pro Leu Phe Phe Gly Thr Ala Val Phe Ala Phe Glu Gly Ile Gly Val
             20                  25                  30

Val Leu Pro Leu Glu Asn Gln Met Lys Glu Ser Lys Arg Phe Pro Gln
         35                  40                  45

Ala Leu Asn Ile Gly Met Gly Ile Val Thr Thr Leu Tyr Val Thr Leu
     50                  55                  60

Ala Thr Leu Gly Tyr Met Cys Phe His Asp Glu Ile Lys Gly Ser Ile
 65                  70                  75                  80

Thr Leu Asn Xaa Pro Gln Asp Val Trp Leu Tyr Gln Ser Val Lys Ile
                 85                  90                  95

Leu Tyr Ser Phe Gly Ile Phe Val Thr Tyr Ser Ile Gln Phe Tyr Val
            100                 105                 110

Pro Ala Glu Ile Ile Ile Pro Gly Ile Thr Ser Lys Phe His Thr Lys
        115                 120                 125

Trp Lys Gln Ile Cys Glu Phe Gly Ile Arg Ser Phe Leu Val Ser Ile
    130                 135                 140

Leu Val Pro Glu Gln Phe Leu Phe Pro Phe Xaa His Cys Asp Phe Phe
145                 150                 155                 160

Val Gly Ala Val Ser Ser Ser Thr Leu Ala Leu Ile Leu Pro Pro Leu
                165                 170                 175

Val Glu Ile Leu Xaa Phe Xaa Xaa Gly Thr Leu Tyr Xaa Gly Gly Pro
            180                 185                 190

Glu Lys Ile Phe Xaa Xaa Phe Leu Xaa Phe Val Trp Ala Xaa 
        195                 200                 205



<210> 2139
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2139
Met Ala Val Ser Leu Val Ile Ile Tyr Gln Tyr Val Val Arg Asn Met
  1               5                  10                  15

Pro Asp Pro His Asn Leu Pro Ile Val Ala Gly Trp Lys Lys Tyr Pro
             20                  25                  30

Leu Phe Phe Gly Thr Ala Val Phe Ala Phe Glu Gly Ile Gly Val Val
         35                  40                  45

Leu Pro Leu Glu Asn Gln Met Lys Glu Ser Lys Arg Phe Pro Gln Ala
     50                  55                  60

Leu Asn Ile Gly Met Gly Ile Val Thr Thr Leu Tyr Val Thr Leu Ala
 65                  70                  75                  80

Thr Leu Gly Tyr Met Cys Phe His Asp Glu Ile Lys Gly Ser Ile Thr
                 85                  90                  95

Leu Asn Leu Pro Gln Asp Val Trp Leu Tyr Xaa Xaa Val Xaa Ile Ser
            100                 105                 110

Leu Tyr Ile Leu 
        115



<210> 2140
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2140
Met His Tyr Cys Glu Ala Cys Thr Ala Pro Lys Met Pro Glu Phe Ile
  1               5                  10                  15

Leu Tyr Ala Phe His Ser Thr Tyr Arg Lys Leu Pro Trp Lys Asp Leu
             20                  25                  30

His Pro Asp Gln Met Leu Met Glu Ala Phe Phe Lys Val Glu Arg Gly
         35                  40                  45

Ser Pro Lys Ser Cys Phe Leu Phe Leu Gly Ser Val Leu Cys Glu Val
     50                  55                  60

Asn Trp Val Ser Val Leu Ser Asp Ala Trp Asn Ser Ser Pro His Pro
 65                  70                  75                  80

Xaa Thr Arg Ser Met Ile Val Cys Leu Leu Phe Met Met Ile Leu Leu
                 85                  90                  95

Ala Lys Glu Val Gln Leu Val Xaa Gln Thr Asp Ser Pro Leu Leu Xaa
            100                 105                 110

Leu Leu Gly Gln Thr Ser Ser Leu 
        115                 120



<210> 2141
<211> 147
<212> PRT
<213> Homo sapiens

<400> 2141
Met Ser Gln Ile Leu Pro Leu Ser Gly Thr Leu Leu Tyr Tyr Arg Arg
  1               5                  10                  15

Phe Pro Gly Leu Met Leu Leu Ser Phe Lys Leu Gln Ile Thr Ser Cys
             20                  25                  30

Thr Val Ser Arg Asn Glu Lys Asp Gln Gln Ser Leu Leu Phe Phe Pro
         35                  40                  45

Ala Asn Ile Leu Ser Phe Gln Leu Ala Met Gln Gly Asn Thr Val Ile
     50                  55                  60

Phe Ile Val Phe Thr Val Val Ala Phe Leu Trp Ile Thr Ser Gln Ala
 65                  70                  75                  80

Ala Ser Asn Leu Leu Val Phe Val Ala Val Ile Pro Glu Ser Lys Val
                 85                  90                  95

Ser Ser Ser Ser Glu Ser Leu Gly Ser Cys Ser Glu Asn Ser Ile Phe
            100                 105                 110

Leu Phe Val Phe Leu Gln Gln Cys Lys Val Pro Phe Pro Phe Leu Gly
        115                 120                 125

Tyr Thr Ala Ser Phe Phe Phe Phe Phe Leu Phe Leu Val Asn Arg Val
    130                 135                 140

Arg Pro Cys 
145



<210> 2142
<211> 274
<212> PRT
<213> Homo sapiens

<400> 2142
Met Gly Lys Ser Leu Ser His Leu Pro Leu His Ser Ser Lys Glu Asp
  1               5                  10                  15

Ala Tyr Asp Gly Val Thr Ser Glu Asn Met Arg Asn Gly Leu Val Asn
             20                  25                  30

Ser Glu Val His Asn Glu Asp Gly Arg Asn Gly Asp Val Ser Gln Phe
         35                  40                  45

Pro Tyr Val Glu Phe Thr Gly Arg Asp Ser Val Thr Cys Pro Thr Cys
     50                  55                  60

Gln Gly Thr Gly Arg Ile Pro Arg Gly Gln Glu Asn Gln Leu Val Ala
 65                  70                  75                  80

Leu Ile Pro Tyr Ser Asp Gln Arg Leu Arg Pro Arg Arg Thr Lys Leu
                 85                  90                  95

Tyr Val Met Ala Ser Val Phe Val Cys Leu Leu Leu Ser Gly Leu Ala
            100                 105                 110

Val Phe Phe Leu Phe Pro Arg Ser Ile Asp Val Lys Tyr Ile Gly Val
        115                 120                 125

Lys Ser Ala Tyr Val Ser Tyr Asp Val Gln Lys Arg Thr Ile Tyr Leu
    130                 135                 140

Asn Ile Thr Asn Thr Leu Asn Ile Thr Asn Asn Asn Tyr Tyr Ser Val
145                 150                 155                 160

Glu Val Glu Asn Ile Thr Ala Gln Val Gln Phe Ser Lys Thr Val Ile
                165                 170                 175

Gly Lys Ala Arg Leu Asn Asn Ile Ser Ile Ile Gly Pro Leu Asp Met
            180                 185                 190

Lys Gln Ile Asp Tyr Thr Val Pro Thr Val Ile Ala Glu Glu Met Ser
        195                 200                 205

Tyr Met Tyr Asp Phe Cys Thr Leu Ile Ser Ile Lys Val His Asn Ile
    210                 215                 220

Val Leu Met Met Gln Val Thr Val Thr Thr Thr Tyr Phe Gly His Ser
225                 230                 235                 240

Glu Gln Ile Ser Gln Glu Arg Tyr Gln Tyr Val Asp Cys Gly Arg Asn
                245                 250                 255

Thr Thr Tyr Gln Leu Gly Gln Ser Glu Tyr Leu Asn Val Leu Gln Pro
            260                 265                 270

Gln Gln 




<210> 2143
<211> 497
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (181)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2143
Met Gly Ser Asn Ser Ser Arg Ile Gly Asp Leu Pro Lys Asn Glu Tyr
  1               5                  10                  15

Leu Lys Lys Leu Ser Gly Thr Glu Ser Ile Ser Glu Asn Asp Pro Phe
             20                  25                  30

Trp Asn Gln Leu Leu Ser Phe Ser Phe Pro Ala Pro Thr Ser Ser Ser
         35                  40                  45

Glu Leu Lys Leu Leu Glu Glu Ala Thr Ile Ser Val Cys Arg Ser Leu
     50                  55                  60

Val Glu Asn Asn Pro Arg Thr Gly Asn Leu Gly Ala Leu Ile Lys Val
 65                  70                  75                  80

Phe Leu Ser Arg Thr Lys Glu Leu Lys Leu Ser Ala Glu Cys Gln Asn
                 85                  90                  95

His Ile Phe Ile Trp Gln Thr His Asn Ala Leu Phe Ile Ile Cys Cys
            100                 105                 110

Leu Leu Lys Val Phe Ile Cys Gln Met Ser Glu Glu Glu Leu Gln Leu
        115                 120                 125

His Phe Thr Tyr Glu Glu Lys Ser Pro Gly Asn Tyr Ser Ser Asp Ser
    130                 135                 140

Glu Asp Leu Leu Glu Glu Leu Leu Cys Cys Leu Met Gln Leu Ile Thr
145                 150                 155                 160

Asp Ile Pro Leu Leu Asp Ile Thr Tyr Glu Ile Ser Val Glu Ala Ile
                165                 170                 175

Ser Thr Met Val Xaa Phe Leu Ser Cys Gln Leu Phe His Lys Glu Val
            180                 185                 190

Leu Arg Gln Ser Ile Ser His Lys Tyr Leu Met Arg Gly Pro Cys Leu
        195                 200                 205

Pro Tyr Thr Ser Lys Leu Val Lys Thr Leu Leu Tyr Asn Phe Ile Arg
    210                 215                 220

Gln Glu Lys Pro Pro Pro Pro Gly Ala His Val Phe Pro Gln Gln Ser
225                 230                 235                 240

Asp Gly Gly Gly Leu Leu Tyr Gly Leu Ala Ser Gly Val Ala Thr Gly
                245                 250                 255

Leu Trp Thr Val Phe Thr Leu Gly Gly Val Gly Ser Lys Ala Ala Ala
            260                 265                 270

Ser Pro Glu Leu Ser Ser Pro Leu Ala Asn Gln Ser Leu Leu Leu Leu
        275                 280                 285

Leu Val Leu Ala Asn Leu Thr Asp Ala Ser Asp Ala Pro Asn Pro Tyr
    290                 295                 300

Arg Gln Ala Ile Met Ser Phe Lys Asn Thr Gln Asp Ser Ser Pro Phe
305                 310                 315                 320

Pro Ser Ser Ile Pro His Ala Phe Gln Ile Asn Phe Asn Ser Leu Tyr
                325                 330                 335

Thr Ala Leu Cys Glu Gln Gln Thr Ser Asp Gln Ala Thr Leu Leu Leu
            340                 345                 350

Tyr Thr Leu Leu His Gln Asn Ser Asn Ile Arg Thr Tyr Met Leu Ala
        355                 360                 365

Arg Thr Asp Met Glu Asn Leu Val Leu Pro Ile Leu Glu Ile Leu Tyr
    370                 375                 380

His Val Glu Glu Arg Asn Ser His His Val Tyr Met Ala Leu Ile Ile
385                 390                 395                 400

Leu Leu Ile Leu Thr Glu Asp Asp Gly Phe Asn Arg Ser Ile His Glu
                405                 410                 415

Val Ile Leu Lys Asn Ile Thr Trp Tyr Ser Glu Arg Val Phe Tyr Pro
            420                 425                 430

Leu Cys Leu Val Ser Cys Leu Gln Leu Ser Ser Arg Pro Val Leu Glu
        435                 440                 445

Ser Thr Gly His Pro Ala Val His His Gly Phe Arg Leu Arg Ala Gly
    450                 455                 460

Cys Ser Pro Thr Arg Thr Pro Pro Ala Lys Gln Pro Phe Lys Phe Phe
465                 470                 475                 480

Tyr Phe Trp Val Thr Glu Val Asp Arg Gln Val Thr Trp Cys Ile Phe
                485                 490                 495

Cys 




<210> 2144
<211> 180
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2144
Met Ile Asn Phe Ser Ala Phe Leu Gly Ala Ala Thr Met Tyr Thr Arg
  1               5                  10                  15

Tyr Lys Ile Val Gln Lys Gln Asn Gln Thr Cys Tyr Phe Ser Thr Pro
             20                  25                  30

Val Phe Asn Leu Val Ser Leu Val Leu Gly Leu Val Gly Cys Phe Gly
         35                  40                  45

Met Gly Ile Val Ala Asn Phe Gln Glu Leu Ala Val Pro Val Val His
     50                  55                  60

Asp Gly Gly Ala Leu Leu Ala Phe Val Cys Gly Val Val Tyr Thr Leu
 65                  70                  75                  80

Leu Xaa Ser Ile Ile Ser Tyr Lys Ser Cys Pro Gln Trp Asn Ser Leu
                 85                  90                  95

Ser Thr Cys His Ile Arg Met Val Ile Ser Ala Val Ser Cys Ala Ala
            100                 105                 110

Val Ile Pro Met Ile Val Cys Ala Ser Leu Ile Ser Ile Thr Lys Leu
        115                 120                 125

Glu Trp Asn Pro Arg Glu Lys Asp Tyr Val Tyr His Val Val Ser Ala
    130                 135                 140

Ile Cys Glu Trp Thr Val Ala Phe Gly Phe Ile Phe Tyr Phe Leu Thr
145                 150                 155                 160

Phe Ile Gln Asp Phe Gln Ser Val Thr Leu Arg Ile Ser Thr Glu Ile
                165                 170                 175

Asn Gly Asp Ile 
            180



<210> 2145
<211> 149
<212> PRT
<213> Homo sapiens

<400> 2145
Met Val Thr Thr Pro Thr Gly Tyr Lys Tyr Glu Gly Val Lys Phe Glu
  1               5                  10                  15

Lys Gly Asn Cys Gly Val Ser Ile Met Arg Ser Gly Glu Ala Met Glu
             20                  25                  30

Gln Gly Leu Arg Asp Cys Cys Arg Ser Ile Arg Ile Gly Lys Ile Leu
         35                  40                  45

Ile Gln Ser Asp Glu Glu Thr Gln Arg Ala Lys Val Tyr Tyr Ala Lys
     50                  55                  60

Phe Pro Pro Asp Ile Tyr Arg Arg Lys Val Leu Leu Met Tyr Pro Ile
 65                  70                  75                  80

Leu Ser Thr Gly Asn Thr Val Ile Glu Ala Val Lys Val Leu Ile Glu
                 85                  90                  95

His Gly Val Gln Pro Ser Val Ile Ile Leu Leu Ser Leu Phe Ser Thr
            100                 105                 110

Pro His Gly Ala Lys Ser Ile Ile Gln Glu Phe Pro Glu Ile Thr Ile
        115                 120                 125

Leu Thr Thr Glu Val His Pro Val Ala Pro Thr His Phe Gly Gln Lys
    130                 135                 140

Tyr Phe Gly Thr Asp 
145



<210> 2146
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2146
Met Glu Lys Pro Leu Phe Pro Leu Val Pro Leu His Trp Phe Gly Phe
  1               5                  10                  15

Gly Tyr Thr Ala Leu Val Val Ser Gly Gly Ile Val Gly Tyr Val Lys
             20                  25                  30

Thr Gly Ser Val Pro Ser Leu Ala Ala Gly Leu Leu Phe Gly Ser Leu
         35                  40                  45

Ala Gly Leu Gly Ala Tyr Gln Leu Tyr Gln Asp Pro Arg Asn Val Trp
     50                  55                  60

Gly Phe Leu Ala Ala Thr Ser Val Thr Phe Val Gly Val Met Gly Met
 65                  70                  75                  80

Arg Ser Tyr Tyr Tyr Gly Lys Phe Met Pro Val Gly Leu Ile Ala Gly
                 85                  90                  95

Ala Ser Leu Leu Met Ala Ala Lys Val Gly Val Arg Met Leu Met Thr
            100                 105                 110

Ser Asp 




<210> 2147
<211> 254
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (201)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2147
Met Ala Leu Leu Val Asp Arg Val Arg Gly His Trp Arg Ile Ala Ala
  1               5                  10                  15

Gly Leu Leu Phe Asn Leu Leu Val Ser Ile Cys Ile Val Phe Leu Asn
             20                  25                  30

Lys Trp Ile Tyr Val Tyr His Gly Phe Pro Asn Met Ser Leu Thr Leu
         35                  40                  45

Val His Phe Val Val Thr Trp Leu Gly Leu Tyr Ile Xaa Gln Lys Leu
     50                  55                  60

Asp Ile Phe Ala Pro Lys Ser Leu Pro Pro Ser Arg Leu Leu Leu Leu
 65                  70                  75                  80

Ala Leu Ser Phe Cys Gly Phe Val Val Phe Thr Asn Leu Ser Leu Gln
                 85                  90                  95

Asn Asn Thr Ile Gly Thr Tyr Gln Leu Ala Lys Ala Met Thr Thr Pro
            100                 105                 110

Val Ile Ile Ala Ile Gln Thr Phe Cys Tyr Gln Lys Thr Phe Ser Thr
        115                 120                 125

Arg Ile Gln Leu Thr Leu Ile Pro Ile Thr Leu Gly Val Ile Leu Asn
    130                 135                 140

Ser Tyr Tyr Asp Val Lys Phe Asn Phe Leu Gly Met Val Xaa Ala Ala
145                 150                 155                 160

Leu Gly Xaa Leu Xaa Thr Ser Leu Tyr Gln Val Trp Val Gly Ala Lys
                165                 170                 175

Gln His Glu Leu Gln Val Asn Ser Met Gln Leu Leu Ser Thr Arg Leu
            180                 185                 190

Arg Cys His Leu Xaa Cys Cys Trp Xaa Leu Cys Pro Ser Leu Ser Gln
        195                 200                 205

Cys Leu Glu Lys Glu Glu Tyr Leu Val Pro Gly Gln Phe Leu Leu Cys
    210                 215                 220

Arg Pro Gly Trp Asn Ala Val Ala Gln Ser Trp Leu Thr Ala Ala Ser
225                 230                 235                 240

Ala Ser Trp Ala Gln Ala Ile Leu Leu Pro Gln Pro Pro Gln 
                245                 250



<210> 2148
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2148
Met Val Ser Met Ser Phe Lys Arg Asn Arg Ser Asp Arg Phe Tyr Ser
  1               5                  10                  15

Thr Arg Cys Cys Gly Cys Cys His Val Arg Thr Gly Thr Ile Ile Leu
             20                  25                  30

Gly Thr Trp Tyr Met Val Val Asn Leu Leu Met Ala Ile Leu Leu Thr
         35                  40                  45

Val Glu Val Thr His Pro Asn Ser Met Pro Ala Val Asn Ile Gln Tyr
     50                  55                  60

Glu Val Ile Gly Asn Tyr Tyr Ser Ser Glu Arg Met Ala Asp Asn Ala
 65                  70                  75                  80

Cys Val Leu Phe Ala Val Ser Val Leu Met Phe Ile Ile Ser Ser Met
                 85                  90                  95

Leu Val Met Glu Gln Phe Leu Ser Ser Gly Leu Ala Asp Ser Ile Phe
            100                 105                 110

Cys Tyr Arg Xaa Phe Asp Phe Xaa Leu Ser Cys Leu Val Ala Ile Ser
        115                 120                 125

Ser Leu Thr Xaa Leu Pro Lys Asn Gln Arg Ile Xaa Gly Ser Thr Thr
    130                 135                 140






<210> 2149
<211> 233
<212> PRT
<213> Homo sapiens

<400> 2149
Met Val Ser Met Ser Phe Lys Arg Asn Arg Ser Asp Arg Phe Tyr Ser
  1               5                  10                  15

Thr Arg Cys Cys Gly Cys Cys His Val Arg Thr Gly Thr Ile Ile Leu
             20                  25                  30

Gly Thr Trp Tyr Met Val Val Asn Leu Leu Met Ala Ile Leu Leu Thr
         35                  40                  45

Val Glu Val Thr His Pro Asn Ser Met Pro Ala Val Asn Ile Gln Tyr
     50                  55                  60

Glu Val Ile Gly Asn Tyr Tyr Ser Ser Glu Arg Met Ala Asp Asn Ala
 65                  70                  75                  80

Cys Val Leu Phe Ala Val Ser Val Leu Met Phe Ile Ile Ser Ser Met
                 85                  90                  95

Leu Val Tyr Gly Ala Ile Ser Tyr Gln Val Gly Trp Leu Ile Pro Phe
            100                 105                 110

Phe Cys Tyr Arg Leu Phe Asp Phe Val Leu Ser Cys Leu Val Ala Ile
        115                 120                 125

Ser Ser Leu Thr Tyr Leu Pro Arg Ile Lys Glu Tyr Leu Asp Gln Leu
    130                 135                 140

Pro Asp Phe Pro Tyr Lys Asp Asp Leu Leu Ala Leu Asp Ser Ser Cys
145                 150                 155                 160

Leu Leu Phe Ile Val Leu Val Phe Phe Ala Leu Phe Ile Ile Phe Lys
                165                 170                 175

Ala Tyr Leu Ile Asn Cys Val Trp Asn Cys Tyr Lys Tyr Ile Asn Asn
            180                 185                 190

Arg Asn Val Pro Glu Ile Ala Val Tyr Pro Ala Phe Glu Ala Pro Pro
        195                 200                 205

Gln Tyr Val Leu Pro Thr Tyr Glu Met Ala Val Lys Met Pro Glu Lys
    210                 215                 220

Glu Pro Pro Pro Pro Tyr Leu Pro Ala 
225                 230



<210> 2150
<211> 233
<212> PRT
<213> Homo sapiens

<400> 2150
Met Ser Asn Ala Leu Ser Thr Val Thr Arg Gly Ser Met Lys Lys Val
  1               5                  10                  15

Phe Pro Pro Asp Glu Ile Glu Gln Val Ser Asn Lys Asp Asp Met Lys
             20                  25                  30

Thr Ser Leu Lys Lys Val Val Lys Glu Thr Ser Tyr Glu Met Met Met
         35                  40                  45

Gln Cys Val Ser Arg Met Leu Ala His Pro Leu His Val Ile Ser Met
     50                  55                  60

Arg Cys Met Val Gln Phe Val Gly Arg Glu Ala Lys Tyr Ser Gly Val
 65                  70                  75                  80

Leu Ser Ser Ile Gly Lys Ile Phe Lys Glu Glu Gly Leu Leu Gly Phe
                 85                  90                  95

Phe Val Gly Leu Ile Pro His Leu Leu Gly Asp Val Val Phe Leu Trp
            100                 105                 110

Gly Cys Asn Leu Leu Ala His Phe Ile Asn Ala Tyr Leu Val Asp Asp
        115                 120                 125

Ser Val Ser Asp Thr Pro Gly Gly Leu Gly Asn Asp Gln Asn Pro Gly
    130                 135                 140

Ser Gln Phe Ser Gln Ala Leu Ala Ile Arg Ser Tyr Thr Lys Phe Val
145                 150                 155                 160

Met Gly Ile Ala Val Ser Met Leu Thr Tyr Pro Phe Leu Leu Val Gly
                165                 170                 175

Asp Leu Met Ala Val Asn Asn Cys Gly Leu Gln Ala Gly Leu Pro Pro
            180                 185                 190

Tyr Ser Pro Val Phe Lys Ser Trp Ile His Cys Trp Lys Tyr Leu Ser
        195                 200                 205

Val Gln Gly Gln Leu Phe Arg Gly Ser Ser Leu Leu Phe Arg Arg Val
    210                 215                 220

Ser Ser Gly Ser Cys Phe Ala Leu Glu 
225                 230



<210> 2151
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2151
Met Trp Phe Leu Val Gly Cys Asn Leu Leu Ala Thr Ser Ser Met Pro
  1               5                  10                  15

Thr Trp Trp Met Thr Ser Val Ser Asp Thr Pro Gly Gly Leu Gly Asn
             20                  25                  30

Asp Gln Asn Pro Gly Ser Gln Phe Xaa Gln Ala Leu Ala Ile Arg Ser
         35                  40                  45

Tyr Thr Lys Phe Val Met Gly Ile Ala Val Ser Met Leu Thr Tyr Pro
     50                  55                  60

Phe Leu Leu Val Gly Asp Leu Met Ala Val Asn Asn Cys Gly Leu Gln
 65                  70                  75                  80

Ala Gly Leu Pro Pro Tyr Xaa Pro Val Xaa Lys Ser Trp Ile His Cys
                 85                  90                  95

Trp Lys Tyr Leu Ser Val Xaa Gly Gln Leu Phe Arg Ser Ser Ser Leu
            100                 105                 110

Leu Phe Arg Arg Val Ser Ser Xaa Ser Cys Phe Gly Leu Glu Leu Pro
        115                 120                 125

Glu Ser Ser 
    130



<210> 2152
<211> 286
<212> PRT
<213> Homo sapiens

<400> 2152
Met Ala Gly Ala Gly Ala Gly Ala Gly Ala Arg Gly Gly Ala Ala Ala
  1               5                  10                  15

Gly Val Glu Ala Arg Ala Arg Asp Pro Pro Pro Ala His Arg Ala His
             20                  25                  30

Pro Arg His Pro Arg Pro Ala Ala Gln Pro Ser Ala Arg Arg Met Asp
         35                  40                  45

Gly Gly Ser Gly Gly Leu Gly Ser Gly Asp Asn Ala Pro Thr Thr Glu
     50                  55                  60

Ala Leu Phe Val Ala Leu Gly Ala Gly Val Thr Ala Leu Ser His Pro
 65                  70                  75                  80

Leu Leu Tyr Val Lys Leu Leu Ile Gln Val Gly His Glu Pro Met Pro
                 85                  90                  95

Pro Thr Leu Gly Thr Asn Val Leu Gly Arg Lys Val Leu Tyr Leu Pro
            100                 105                 110

Ser Phe Phe Thr Tyr Ala Lys Tyr Ile Val Gln Val Asp Gly Lys Ile
        115                 120                 125

Gly Leu Phe Arg Gly Leu Ser Pro Arg Leu Met Ser Asn Ala Leu Ser
    130                 135                 140

Thr Val Thr Arg Gly Ser Met Lys Lys Val Phe Pro Pro Asp Glu Ile
145                 150                 155                 160

Glu Gln Val Ser Asn Lys Asp Asp Met Lys Thr Ser Leu Lys Lys Val
                165                 170                 175

Val Lys Glu Thr Ser Tyr Glu Met Met Met Gln Cys Val Ser Arg Met
            180                 185                 190

Leu Ala His Pro Leu His Val Ile Ser Met Arg Cys Met Val Gln Phe
        195                 200                 205

Val Gly Arg Glu Ala Lys Tyr Ser Gly Val Leu Ser Ser Ile Gly Lys
    210                 215                 220

Ile Phe Lys Glu Glu Gly Leu Leu Gly Phe Phe Val Val Arg Glu Phe
225                 230                 235                 240

Ile His Pro Ile Thr Gly His Gly His Gly Ser Ala Asn Arg Cys Val
                245                 250                 255

Leu Asn Leu Ser Asp Arg Ser Cys Trp Pro Gly Thr Ser Leu His Gly
            260                 265                 270

Pro Ala Leu Pro Glu Cys Cys Ser Gln Leu Ser Arg Ala Pro 
        275                 280                 285



<210> 2153
<211> 118
<212> PRT
<213> Homo sapiens

<400> 2153
Met Glu Asp Leu Gln Phe Glu Asn Trp Gly Pro Val Pro Lys Ser Val
  1               5                  10                  15

Ile Val Leu Thr Thr Cys Ile Thr Ala Leu Leu Asp Thr Gln Glu Ser
             20                  25                  30

His Gly Asn Ala Asn Trp Lys Gly Pro Leu Pro Gln Gly Ser Leu Arg
         35                  40                  45

Arg Arg Gly Ser Val Glu Ser Lys Pro Thr Phe Pro Lys Ser Pro Pro
     50                  55                  60

Thr Arg Pro Leu Thr Pro Ser Thr Val Arg Leu Tyr Val Ser Gly Ile
 65                  70                  75                  80

Gln Gly Asn Val Asn Phe Leu Phe Ile Trp Glu Ile Val His Gly Lys
                 85                  90                  95

Gln Ile Phe Phe Ser Leu Val His Leu Leu Ile Val Tyr Asn Ile Cys
            100                 105                 110

Thr Ser Met Gln Asn Thr 
        115



<210> 2154
<211> 129
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2154
Met Ser Glu Lys Glu Asn Asn Phe Pro Pro Leu Pro Lys Phe Ile Pro
  1               5                  10                  15

Val Lys Pro Cys Phe Tyr Gln Asn Phe Ser Asp Glu Ile Pro Val Glu
             20                  25                  30

His Gln Val Leu Val Lys Arg Ile Tyr Arg Leu Trp Met Phe Tyr Cys
         35                  40                  45

Ala Thr Leu Gly Val Asn Leu Ile Ala Cys Leu Ala Trp Trp Ile Gly
     50                  55                  60

Gly Gly Ser Gly Thr Asn Phe Gly Leu Ala Xaa Val Trp Leu Leu Leu
 65                  70                  75                  80

Phe Thr Pro Cys Gly Tyr Val Cys Trp Phe Arg Pro Val Xaa Lys Ala
                 85                  90                  95

Ser Xaa Ala Asp Ser Ser Phe Asn Phe Met Ala Phe Phe Phe Ile Phe
            100                 105                 110

Gly Ala Gln Phe Val Xaa Thr Val Ile Gln Ala Ile Gly Ser Pro Ala
        115                 120                 125

Gly 




<210> 2155
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2155
Met Ser Glu Val Gly Glu Gly Trp Thr Gly Ser Ser Ser Arg Arg Ser
  1               5                  10                  15

Xaa Ser Pro Thr Pro Ser Pro Pro Pro Gly Lys Trp Pro Gln Arg Ser
             20                  25                  30

Ser Leu Phe Pro Ser Pro Glu Trp Val Ser Arg Ser Ala Phe Arg Asp
         35                  40                  45

Pro Val Leu His Trp Ala Thr Phe Arg Ala Ala Leu Gly Arg Gln Ser
     50                  55                  60

Cys Phe Ser Xaa Ser Gln Asn Pro Phe Pro Ser Pro Leu Arg Ser Cys
 65                  70                  75                  80

Lys Glu Lys Gly Thr Val Tyr Ile Leu Ser Pro Phe Ile Ile His Phe
                 85                  90                  95

Ser Ala Val Pro Gly Ile Thr Trp Leu Trp Asn Ile Leu Ser Gly Lys
            100                 105                 110

Lys Ile Tyr Pro Leu Lys Lys Leu Glu Lys Ser Lys Ser Gly Pro Gly
        115                 120                 125

Xaa Ser Gly Phe His Ile Cys Ile Xaa Gln His Phe Gly Glu Gly Gln
    130                 135                 140

Gly Gln Val Gly Phe Xaa 
145                 150



<210> 2156
<211> 313
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (200)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (310)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2156
Met Lys Lys Arg Lys Glu Leu Asn Ala Leu Ile Gly Leu Ala Gly Asp
  1               5                  10                  15

Ser Arg Arg Lys Lys Pro Lys Lys Gly Pro Ser Ser His Arg Leu Leu
             20                  25                  30

Arg Thr Glu Pro Pro Asp Ser Asp Ser Glu Ser Ser Ser Glu Glu Glu
         35                  40                  45

Glu Glu Phe Gly Val Val Gly Asn Arg Ser Arg Phe Ala Lys Gly Asp
     50                  55                  60

Tyr Leu Arg Cys Cys Lys Ile Cys Tyr Pro Leu Cys Gly Phe Val Ile
 65                  70                  75                  80

Leu Ala Ala Cys Val Val Ala Cys Val Gly Leu Val Trp Met Gln Val
                 85                  90                  95

Ala Leu Lys Glu Asp Leu Asp Ala Leu Lys Glu Lys Phe Arg Thr Met
            100                 105                 110

Glu Ser Asn Gln Lys Ser Ser Phe Gln Glu Ile Pro Lys Leu Asn Glu
        115                 120                 125

Glu Leu Leu Ser Lys Gln Lys Gln Leu Glu Lys Ile Glu Ser Gly Glu
    130                 135                 140

Met Gly Leu Asn Lys Val Trp Ile Asn Ile Thr Glu Met Asn Lys Gln
145                 150                 155                 160

Ile Ser Leu Leu Thr Ser Ala Val Asn His Leu Lys Ala Asn Val Lys
                165                 170                 175

Ser Ala Ala Asp Leu Ile Ser Leu Pro Thr Thr Val Glu Gly Leu Gln
            180                 185                 190

Lys Ser Val Ala Ser Ile Gly Xaa Thr Leu Asn Ser Val His Leu Ala
        195                 200                 205

Val Glu Ala Leu Gln Lys Thr Val Asp Glu His Lys Lys Thr Met Glu
    210                 215                 220

Leu Leu Gln Ser Asp Met Asn Gln His Phe Leu Lys Glu Thr Pro Gly
225                 230                 235                 240

Ser Asn Gln Ile Ile Pro Ser Pro Ser Ala Thr Ser Glu Leu Asp Asn
                245                 250                 255

Lys Thr His Ser Glu Asn Leu Lys Gln Met Gly Asp Arg Ser Ala Thr
            260                 265                 270

Leu Lys Arg Gln Ser Leu Asp Gln Val Thr Asn Arg Thr Asp Thr Val
        275                 280                 285

Lys Ile Gln Ser Ile Lys Lys Glu Asp Ser Ser Lys Phe Ser Arg Tyr
    290                 295                 300

Pro Lys Leu Lys Arg Xaa Thr Pro Ala 
305                 310



<210> 2157
<211> 160
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2157
Met Ala Arg Ala Ser Ser Gly Asn Gly Ser Glu Glu Ala Trp Gly Ala
  1               5                  10                  15

Leu Arg Ala Pro Gln Gln Gln Leu Arg Glu Leu Cys Pro Gly Val Asn
             20                  25                  30

Asn Gln Pro Tyr Leu Cys Glu Ser Gly His Cys Cys Gly Glu Thr Gly
         35                  40                  45

Cys Cys Thr Tyr Tyr Tyr Glu Leu Trp Trp Phe Trp Leu Leu Trp Thr
     50                  55                  60

Val Leu Ile Leu Phe Ser Cys Cys Cys Ala Phe Arg His Arg Arg Ala
 65                  70                  75                  80

Lys Leu Arg Leu Gln Gln Gln Gln Arg Gln Arg Glu Ile Asn Leu Leu
                 85                  90                  95

Ala Tyr His Gly Ala Cys His Gly Ala Gly Pro Phe Pro Thr Gly Ser
            100                 105                 110

Leu Leu Asp Leu Arg Phe Leu Ser Thr Phe Lys Ala Pro Ser Leu Arg
        115                 120                 125

Xaa Cys Gly Ser Xaa Pro Xaa His Thr Asn Pro Pro Leu Xaa Cys Gly
    130                 135                 140

Pro Arg Arg Pro Phe Asp Xaa Phe Ser Xaa Gln Thr Xaa Trp Ser Phe
145                 150                 155                 160






<210> 2158
<211> 228
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2158
Met Gly Met Ser Pro Leu Leu Gln Ala His His Ala Met Glu Lys Met
  1               5                  10                  15

Glu Glu Phe Val Cys Lys Val Trp Glu Gly Arg Trp Arg Val Ile Pro
             20                  25                  30

His Asp Val Leu Pro Asp Trp Leu Lys Asp Asn Asp Phe Leu Leu His
         35                  40                  45

Gly His Arg Pro Pro Met Pro Ser Phe Arg Ala Cys Phe Lys Ser Ile
     50                  55                  60

Phe Arg Ile His Thr Glu Thr Gly Asn Ile Trp Thr His Leu Leu Gly
 65                  70                  75                  80

Cys Val Phe Phe Leu Cys Leu Gly Ile Phe Tyr Met Phe Arg Pro Asn
                 85                  90                  95

Ile Ser Phe Val Ala Pro Leu Gln Glu Lys Val Val Phe Gly Leu Phe
            100                 105                 110

Phe Leu Gly Ala Ile Leu Cys Leu Ser Phe Ser Trp Leu Phe His Thr
        115                 120                 125

Val Tyr Cys His Ser Xaa Gly Val Ser Arg Leu Phe Ser Lys Leu Gly
    130                 135                 140

Leu Leu Trp Tyr Cys Ser Ser Glu Leu Trp Glu Val Leu Phe Leu Gly
145                 150                 155                 160

Phe Ile Xaa Leu Ser Thr Val Ile His Asn Leu Xaa His Leu Leu Ile
                165                 170                 175

Val Ile Cys Val Leu Gly His Cys Ser His Tyr Ser Leu Pro Val Gly
            180                 185                 190

His Val Cys His Pro Ser Val Ser Gly Ser Lys Ser Arg Ser Val Phe
        195                 200                 205

Gly Pro Arg Pro Glu Trp Asn His Ser Tyr Leu Ala Leu Cys His Leu
    210                 215                 220

Gly Gly Val Pro 
225



<210> 2159
<211> 816
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (804)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (807)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (813)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2159
Met Ile Phe Val Cys Ser Ala Thr His Lys Thr Lys Ser Met Phe Phe
  1               5                  10                  15

Phe Leu Ala Gln Thr Glu Gln Gly Asp Ile Phe Lys Ile Thr Leu Glu
             20                  25                  30

Thr Asp Glu Asp Met Val Thr Glu Ile Arg Leu Lys Tyr Phe Asp Thr
         35                  40                  45

Val Pro Val Ala Ala Ala Met Cys Val Leu Lys Thr Gly Xaa Leu Phe
     50                  55                  60

Val Ala Ser Glu Phe Gly Asn His Tyr Leu Tyr Gln Ile Ala His Leu
 65                  70                  75                  80

Gly Xaa Asp Asp Glu Glu Pro Glu Phe Ser Ser Ala Met Pro Leu Glu
                 85                  90                  95

Glu Gly Asp Thr Phe Phe Phe Gln Pro Arg Pro Leu Lys Asn Leu Val
            100                 105                 110

Leu Val Asp Glu Leu Asp Ser Leu Ser Pro Ile Leu Phe Cys Gln Ile
        115                 120                 125

Ala Asp Leu Ala Asn Glu Asp Thr Pro Gln Leu Tyr Val Ala Cys Gly
    130                 135                 140

Arg Gly Pro Arg Ser Ser Leu Arg Val Leu Arg His Gly Leu Glu Val
145                 150                 155                 160

Ser Glu Met Ala Val Ser Glu Leu Pro Gly Asn Pro Asn Ala Val Trp
                165                 170                 175

Thr Val Arg Arg His Ile Glu Asp Glu Phe Asp Ala Tyr Ile Ile Val
            180                 185                 190

Ser Phe Val Asn Ala Thr Leu Val Leu Ser Ile Gly Glu Thr Val Glu
        195                 200                 205

Glu Val Thr Asp Ser Gly Phe Leu Gly Thr Thr Pro Thr Leu Ser Cys
    210                 215                 220

Ser Leu Leu Gly Asp Asp Ala Leu Val Gln Val Tyr Pro Asp Gly Ile
225                 230                 235                 240

Arg His Ile Arg Ala Asp Lys Arg Val Asn Glu Trp Lys Thr Pro Gly
                245                 250                 255

Lys Lys Thr Ile Val Lys Cys Ala Val Asn Gln Arg Gln Val Val Ile
            260                 265                 270

Ala Leu Thr Gly Gly Glu Leu Val Tyr Phe Glu Met Asp Pro Ser Gly
        275                 280                 285

Gln Leu Asn Glu Tyr Thr Glu Arg Lys Glu Met Ser Ala Asp Val Val
    290                 295                 300

Cys Met Ser Leu Ala Asn Val Pro Pro Gly Glu Gln Arg Ser Arg Phe
305                 310                 315                 320

Leu Ala Val Gly Leu Val Asp Asn Thr Val Arg Ile Ile Ser Leu Asp
                325                 330                 335

Pro Ser Asp Cys Leu Gln Pro Leu Ser Met Gln Ala Leu Pro Ala Gln
            340                 345                 350

Pro Glu Ser Leu Cys Ile Val Glu Met Gly Gly Thr Glu Lys Gln Asp
        355                 360                 365

Glu Leu Gly Glu Arg Gly Ser Ile Gly Phe Leu Tyr Leu Asn Ile Gly
    370                 375                 380

Leu Gln Asn Gly Val Leu Leu Arg Thr Val Leu Asp Pro Val Thr Gly
385                 390                 395                 400

Asp Leu Ser Asp Thr Arg Thr Arg Tyr Leu Gly Ser Arg Pro Val Lys
                405                 410                 415

Leu Phe Arg Val Arg Met Gln Gly Gln Glu Ala Val Leu Ala Met Ser
            420                 425                 430

Ser Arg Ser Trp Leu Ser Tyr Ser Tyr Gln Ser Arg Phe His Leu Thr
        435                 440                 445

Pro Leu Ser Tyr Glu Thr Leu Glu Phe Ala Ser Gly Phe Ala Ser Glu
    450                 455                 460

Gln Cys Pro Glu Gly Ile Val Ala Ile Ser Thr Asn Thr Leu Arg Ile
465                 470                 475                 480

Leu Ala Leu Glu Lys Leu Gly Ala Val Phe Asn Gln Val Ala Phe Pro
                485                 490                 495

Leu Gln Tyr Thr Pro Arg Lys Phe Val Ile His Pro Glu Ser Asn Asn
            500                 505                 510

Leu Ile Ile Ile Glu Thr Asp His Asn Ala Tyr Thr Glu Ala Thr Lys
        515                 520                 525

Ala Gln Arg Lys Gln Gln Met Ala Glu Glu Met Val Glu Ala Ala Gly
    530                 535                 540

Glu Asp Glu Arg Glu Leu Ala Ala Glu Met Ala Ala Ala Phe Leu Asn
545                 550                 555                 560

Glu Asn Leu Pro Glu Ser Ile Phe Gly Ala Pro Lys Ala Gly Asn Gly
                565                 570                 575

Gln Trp Ala Ser Val Ile Arg Val Met Asn Pro Ile Gln Gly Asn Thr
            580                 585                 590

Leu Asp Leu Val Gln Leu Glu Gln Asn Glu Ala Ala Phe Ser Val Ala
        595                 600                 605

Val Cys Arg Phe Ser Asn Thr Gly Glu Asp Trp Tyr Val Leu Val Gly
    610                 615                 620

Val Ala Lys Asp Leu Ile Leu Asn Pro Arg Ser Val Ala Gly Gly Phe
625                 630                 635                 640

Val Tyr Thr Tyr Lys Leu Val Asn Asn Gly Glu Lys Leu Glu Phe Leu
                645                 650                 655

His Lys Thr Pro Val Glu Glu Val Pro Ala Ala Ile Ala Pro Phe Gln
            660                 665                 670

Gly Arg Val Leu Ile Gly Val Gly Lys Leu Leu Arg Val Tyr Asp Leu
        675                 680                 685

Gly Lys Lys Lys Leu Leu Arg Lys Cys Glu Asn Lys His Ile Ala Asn
    690                 695                 700

Tyr Ile Ser Gly Ile Gln Thr Ile Gly His Arg Val Ile Val Ser Asp
705                 710                 715                 720

Val Gln Glu Ser Phe Ile Trp Val Arg Tyr Lys Arg Asn Glu Asn Gln
                725                 730                 735

Leu Ile Ile Phe Ala Asp Asp Thr Tyr Pro Arg Trp Val Thr Thr Ala
            740                 745                 750

Ser Leu Leu Asp Tyr Asp Thr Val Ala Gly Ala Asp Lys Phe Gly Asn
        755                 760                 765

Ile Cys Val Val Arg Leu Pro Pro Asn Thr Asn Asp Glu Val Asp Glu
    770                 775                 780

Asp Pro Thr Gly Asn Lys Ala Leu Trp Asp Arg Gly Leu Leu Asn Gly
785                 790                 795                 800

Ala Ser Gln Xaa Gly Lys Xaa Arg Gly Gly Phe Gly Xaa Lys Lys Phe
                805                 810                 815






<210> 2160
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2160
Met Trp Phe Gly Ser Gly Val Leu Met Ala Arg Val Leu Ala His Gly
  1               5                  10                  15

Arg Gly Gly Gln Gly Ser Val Gln Glu Pro Val Leu Ala Thr Leu Phe
             20                  25                  30

Leu Thr Ile Gln Ser Leu Ser Pro Ala Cys Ala Leu Ile Val Pro His
         35                  40                  45

Leu His Arg Val Cys Thr Leu Pro Ala Pro Cys Leu Tyr Pro Met Cys
     50                  55                  60

Ala Pro Ser Val Pro Cys Leu Arg His Leu Arg Pro Leu Arg Thr Leu
 65                  70                  75                  80

Ser Val Ser Ser Val Pro Cys Leu Cys Pro Val Arg Ile Pro Leu Arg
                 85                  90                  95

Pro Val Cys Ala Pro Ser Ala Pro Cys Xaa Thr Pro Ser Ile Ser Xaa
            100                 105                 110

Ser Ala Ala Ala Pro Ser Leu His Pro Val Cys Ala Val Val Pro Val
        115                 120                 125

Cys Thr Leu Leu Cys Pro Ser His Pro Ala Cys Thr Leu Leu Cys Pro
    130                 135                 140

Ser Gly Pro Leu Thr Pro Tyr Cys Ala Leu Xaa Val 
145                 150                 155



<210> 2161
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2161
Met Asn Ile Lys His Leu Val Asp Pro Ile Asp Asp Leu Phe Leu Ala
  1               5                  10                  15

Ala Lys Lys Ile Pro Gly Ile Ser Ser Thr Gly Val Gly Asp Gly Gly
             20                  25                  30

Asn Glu Leu Gly Met Gly Lys Val Lys Glu Ala Val Arg Arg His Ile
         35                  40                  45

Arg His Gly Xaa Val Ile Ala Cys Asp Val Glu Ala Asp Phe Ala Val
     50                  55                  60

Ile Ala Gly Val Ser Asn Trp Gly Gly Tyr Ala Leu Ala Cys Ala Leu
 65                  70                  75                  80

Tyr Ile Leu Tyr Ser Cys Ala Val His Ser Gln Tyr Leu Arg Lys Ala
                 85                  90                  95

Val Gly Pro Ser Arg Ala Pro Gly Asp Gln Ala Trp Thr Gln Ala Leu
            100                 105                 110

Pro Ser Val Ile Lys Glu Glu Lys Met Leu Gly Ile Leu Val Gln His
        115                 120                 125

Lys Val Arg Ser Gly Val Ser Gly Ile Val Gly Met Glu Val Asp Gly
    130                 135                 140

Leu Pro Phe His Asn Thr His Ala Glu Met Ile Gln Lys Leu Val Asp
145                 150                 155                 160

Val Thr Thr Ala Gln Val 
                165



<210> 2162
<211> 127
<212> PRT
<213> Homo sapiens

<400> 2162
Met Lys Val Ala Phe Leu Leu Gly Ser Leu Ala Ala Arg Gly Ser Asp
  1               5                  10                  15

Thr Arg Ser Asn Thr Glu Leu Ser Ser Gly Ala Lys Val Phe Pro Val
             20                  25                  30

Ser Ser Ala Arg Glu Pro Ser Pro Pro Ala Ser Phe Arg Ser Gln Cys
         35                  40                  45

Ser Ser Asn Thr Val Tyr Thr Leu Phe Cys Phe Gln Ile Tyr Pro Glu
     50                  55                  60

Ala Leu Leu Ser Ile Asn Asp Tyr Thr Ile Lys Val Ser Val Ile Leu
 65                  70                  75                  80

Glu Leu Ile Ser Val Gly Ile Ser Cys Met Gln Ser Val Ala Phe Arg
                 85                  90                  95

Gly Leu Ser Pro Ile Leu Val Ser Cys Arg Ala Asp Cys Ser Leu His
            100                 105                 110

Leu Asp Leu Asn Glu Gly Leu Trp Leu Glu Cys Val Arg Ser Arg 
        115                 120                 125



<210> 2163
<211> 121
<212> PRT
<213> Homo sapiens

<400> 2163
Met Leu Ser Ala Phe Asn Ala Thr Ser Gly Lys Ala Ile Trp Thr Leu
  1               5                  10                  15

Asn Pro Asn Tyr Leu Ser Asn Gly Thr Leu Ala Ala Pro Val Val Val
             20                  25                  30

Leu Pro Asp Leu Asp Glu Asp Gly Val Arg Asp Leu Val Val Leu Ala
         35                  40                  45

Ile Gly Glu Leu Gln Pro Asp Leu Cys Phe Leu Leu Val Ser Gly Arg
     50                  55                  60

Thr Gly Asn Pro Val Gly Arg Pro Val Lys Tyr Asn Ile Val Gly Ser
 65                  70                  75                  80

Trp Glu Ser Glu Leu Val Leu Arg Phe Thr Ser Pro Gln Met Gly Leu
                 85                  90                  95

Ser Thr Ser Cys Leu Gly Leu Glu Ile Tyr Lys Leu Ser His Cys Gly
            100                 105                 110

Asp Ile Phe Val Pro Gly Pro Lys Ser 
        115                 120



<210> 2164
<211> 373
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (278)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2164
Met Trp Val Cys Ser Thr Leu Trp Arg Val Arg Thr Pro Ala Arg Gln
  1               5                  10                  15

Trp Arg Gly Leu Leu Pro Ala Ser Gly Cys His Gly Pro Ala Ala Ser
             20                  25                  30

Ser Tyr Ser Ala Ser Ala Glu Pro Ala Arg Val Arg Ala Leu Val Tyr
         35                  40                  45

Gly His His Gly Asp Pro Ala Lys Val Val Glu Leu Lys Asn Leu Glu
     50                  55                  60

Leu Ala Ala Val Arg Gly Ser Asp Val Arg Val Lys Met Leu Ala Ala
 65                  70                  75                  80

Pro Ile Asn Pro Ser Asp Ile Asn Met Ile Gln Gly Asn Tyr Gly Xaa
                 85                  90                  95

Leu Pro Glu Leu Pro Ala Val Gly Gly Asn Glu Gly Val Ala Gln Val
            100                 105                 110

Val Ala Val Gly Ser Asn Val Thr Gly Leu Lys Pro Gly Asp Trp Val
        115                 120                 125

Ile Pro Ala Asn Ala Gly Leu Gly Thr Trp Arg Thr Glu Ala Val Phe
    130                 135                 140

Ser Glu Glu Ala Leu Ile Gln Val Pro Ser Asp Ile Pro Leu Gln Ser
145                 150                 155                 160

Ala Ala Thr Leu Gly Val Asn Pro Cys Thr Ala Tyr Arg Met Leu Met
                165                 170                 175

Asp Phe Glu Gln Leu Gln Pro Gly Asp Ser Val Ile Gln Asn Ala Ser
            180                 185                 190

Asn Ser Gly Val Gly Gln Ala Val Ile Gln Ile Ala Ala Ala Leu Gly
        195                 200                 205

Leu Arg Thr Ile Asn Val Val Arg Asp Arg Pro Asp Ile Gln Lys Leu
    210                 215                 220

Ser Asp Arg Leu Lys Ser Leu Gly Ala Glu His Val Ile Thr Glu Glu
225                 230                 235                 240

Glu Leu Arg Arg Pro Glu Met Lys Asn Phe Phe Lys Asp Met Pro Gln
                245                 250                 255

Pro Arg Leu Ala Leu Asn Cys Val Gly Gly Lys Ser Ser Thr Glu Leu
            260                 265                 270

Leu Arg Gln Leu Ala Xaa Gly Gly Thr Met Val Thr Tyr Gly Gly Met
        275                 280                 285

Ala Lys Gln Pro Val Val Ala Ser Val Ser Leu Leu Ile Phe Lys Asp
    290                 295                 300

Leu Lys Leu Arg Gly Phe Trp Leu Ser Gln Trp Lys Lys Asp His Ser
305                 310                 315                 320

Pro Asp Gln Phe Lys Glu Leu Ile Leu Thr Leu Cys Asp Leu Ile Arg
                325                 330                 335

Arg Gly Gln Leu Thr Ala Pro Ala Cys Ser Gln Val Pro Leu Gln Asp
            340                 345                 350

Tyr Gln Ser Ala Leu Glu Ala Ser Met Lys Pro Phe Ile Ser Ser Lys
        355                 360                 365

Gln Ile Leu Thr Met 
    370



<210> 2165
<211> 135
<212> PRT
<213> Homo sapiens

<400> 2165
Met Asn Glu Thr Phe Arg Glu Lys Phe Pro His Val Lys Leu Thr Leu
  1               5                  10                  15

Ser Lys Ile Arg Ser Leu Lys Arg Glu Met Arg Ser Leu Ser Glu Glu
             20                  25                  30

Cys Ser Leu Glu Pro Val Thr Val Ala Met Ala Tyr Val Tyr Phe Glu
         35                  40                  45

Lys Leu Val Leu Gln Gly Lys Leu Ser Lys Gln Asn Arg Lys Leu Cys
     50                  55                  60

Ala Gly Ala Cys Val Leu Leu Ala Ala Lys Ile Ser Ser Asp Leu Arg
 65                  70                  75                  80

Lys Ser Gly Val Lys Gln Leu Ile Asp Lys Leu Glu Glu Arg Phe Arg
                 85                  90                  95

Phe Asn Arg Arg Asp Leu Ile Gly Phe Glu Phe Thr Val Leu Val Ala
            100                 105                 110

Leu Glu Leu Ala Leu Tyr Leu Pro Glu Asn Gln Val Leu Pro His Tyr
        115                 120                 125

Arg Arg Leu Thr Gln Gln Phe 
    130                 135



<210> 2166
<211> 194
<212> PRT
<213> Homo sapiens

<400> 2166
Met Val Cys Pro Ser Ala Glu Ala Gln Asp Pro Phe Pro Thr Val Gly
  1               5                  10                  15

Pro Asn Ser Val Leu Ser Pro Gln Arg Leu Val Leu Glu Thr Leu Cys
             20                  25                  30

Lys Leu Ser Ile Gln Asp Asn Asn Val Asp Leu Ile Leu Ala Thr Pro
         35                  40                  45

Pro Phe Ser Arg Gln Glu Lys Phe Tyr Ala Thr Leu Val Arg Tyr Val
     50                  55                  60

Gly Asp Arg Lys Asn Pro Val Cys Arg Glu Met Ser Met Ala Leu Leu
 65                  70                  75                  80

Ser Asn Leu Ala Gln Gly Asp Ala Leu Ala Ala Arg Ala Ile Ala Val
                 85                  90                  95

Gln Lys Gly Ser Ile Gly Asn Leu Ile Ser Phe Leu Glu Asp Gly Val
            100                 105                 110

Thr Met Ala Gln Tyr Gln Gln Ser Gln His Asn Leu Met His Met Gln
        115                 120                 125

Pro Pro Pro Leu Glu Pro Pro Ser Val Asp Met Met Cys Arg Ala Ala
    130                 135                 140

Lys Ala Leu Leu Ala Met Ala Arg Val Asp Glu Asn Arg Ser Glu Phe
145                 150                 155                 160

Leu Leu His Glu Gly Arg Leu Leu Asp Ile Ser Ile Ser Ala Val Leu
                165                 170                 175

Asn Ser Leu Val Ala Ser Val Ile Cys Asp Val Leu Phe Gln Ile Gly
            180                 185                 190

Gln Leu 




<210> 2167
<211> 145
<212> PRT
<213> Homo sapiens

<400> 2167
Met His Ser Thr Ser Ser His Glu Gly His Lys Gln His Arg Ser Gln
  1               5                  10                  15

Thr Leu Pro Ile Ile Arg Gly Lys Asn Ala Leu Ser Asn Pro Lys Leu
             20                  25                  30

Leu Gln Met Leu Asp Asn Thr Met Thr Ser Asn Ser Asn Glu Ile Asp
         35                  40                  45

Ile Val His His Val Asp Thr Glu Ala Asn Ile Ala Thr Glu Val Cys
     50                  55                  60

Leu Thr Ile Leu Asp Leu Leu Ser Leu Phe Thr Gln Thr His Gln Arg
 65                  70                  75                  80

Gln Leu Gln Gln Cys Asp Cys Gln Asn Ser Leu Met Lys Arg Val Phe
                 85                  90                  95

Asp Thr Tyr Met Leu Phe Phe Gln Val Asn Gln Ser Ala Thr Ala Leu
            100                 105                 110

Lys His Val Phe Ala Ser Leu Arg Leu Phe Val Cys Lys Phe Pro Ser
        115                 120                 125

Ala Phe Phe Gln Gly Pro Ala Asp Leu Cys Gly Ser Phe Cys Tyr Glu
    130                 135                 140

Ser 
145



<210> 2168
<211> 269
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2168
Met Glu Pro Glu Phe Leu Tyr Asp Leu Leu Gln Leu Pro Lys Gly Val
  1               5                  10                  15

Glu Pro Pro Ala Glu Glu Glu Leu Ser Lys Gly Gly Lys Lys Lys Tyr
             20                  25                  30

Leu Pro Pro Thr Ser Arg Lys Asp Pro Lys Phe Glu Glu Leu Gln Lys
         35                  40                  45

Val Leu Met Glu Trp Ile Asn Ala Thr Leu Leu Pro Glu His Ile Val
     50                  55                  60

Val Arg Ser Leu Glu Glu Asp Met Phe Asp Gly Leu Ile Leu His His
 65                  70                  75                  80

Leu Phe Gln Xaa Leu Ala Ala Leu Lys Leu Glu Ala Glu Asp Ile Ala
                 85                  90                  95

Leu Thr Ala Thr Ser Gln Lys His Lys Leu Thr Val Val Leu Glu Ala
            100                 105                 110

Val Asn Arg Ser Leu Gln Leu Glu Glu Trp Gln Ala Lys Trp Ser Val
        115                 120                 125

Glu Ser Ile Phe Asn Lys Asp Leu Leu Ser Thr Leu His Leu Leu Val
    130                 135                 140

Ala Leu Ala Lys Arg Phe Gln Pro Asp Leu Ser Leu Pro Thr Asn Val
145                 150                 155                 160

Gln Val Glu Val Ile Thr Ile Glu Ser Thr Lys Ser Gly Leu Lys Ser
                165                 170                 175

Glu Lys Leu Val Glu Gln Leu Thr Glu Tyr Ser Thr Asp Lys Asp Glu
            180                 185                 190

Pro Pro Lys Asp Val Phe Asp Glu Leu Phe Lys Leu Ala Pro Glu Lys
        195                 200                 205

Val Asn Ala Val Lys Glu Ala Ile Val Asn Phe Val Asn Gln Lys Leu
    210                 215                 220

Asp Arg Leu Gly Leu Ser Val Gln Asn Leu Asp Thr Gln Phe Ala Asp
225                 230                 235                 240

Gly Val Ile Leu Leu Leu Leu Ile Gly Gln Leu Glu Gly Phe Phe Leu
                245                 250                 255

His Leu Lys Glu Phe Tyr Leu Thr Phe Glu Leu Phe Cys 
            260                 265



<210> 2169
<211> 130
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2169
Met Ser Leu Arg Xaa Met Gly Met Thr Ser Leu Cys Gly Asp Trp Leu
  1               5                  10                  15

Gln Gly Leu His Arg Phe Val Ala Arg Glu Lys Ile Met Ser Val Leu
             20                  25                  30

Ser Glu Xaa Gly Leu Phe Arg Gly Leu Gln Asn His Pro Met Val Leu
         35                  40                  45

Pro Ile Cys Ser Arg Ser Gly Asp Val Ile Glu Tyr Leu Leu Lys Asn
     50                  55                  60

Gln Trp Phe Val Arg Cys Gln Glu Met Gly Ala Arg Ala Ala Lys Ala
 65                  70                  75                  80

Val Glu Ser Gly Ala Leu Glu Leu Ser Pro Ser Phe His Gln Lys Asn
                 85                  90                  95

Trp Gln His Trp Val Phe Pro Tyr Trp Gly Leu Val Cys Leu Pro Ala
            100                 105                 110

Xaa Val Val Gly Ala Ile Arg Phe Gln Xaa Asn Leu Val Val Arg Gly
        115                 120                 125

Pro Cys 
    130



<210> 2170
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2170
Met Arg Lys Lys Thr Val Gly Asn Gln Thr Gly Ile Lys Ser Ser Ala
  1               5                  10                  15

Leu Pro Arg Lys Ser Gly Arg Tyr Ser Gly Phe Pro Lys Lys Gln Arg
             20                  25                  30

Lys Arg Arg Ser Leu Asp Glu Glu Thr Val Gln Gln Glu Glu Gly Leu
         35                  40                  45

Leu Thr Leu Ser Cys Ala Cys Gly Ser Pro Glu Asp Pro Val Lys Ile
     50                  55                  60

Gln Ile Leu Ile Gln Trp Val Cys Val Glu Pro Glu Thr Ala Ile Leu
 65                  70                  75                  80

Thr Cys Ser Gln Gly Met Leu Met Leu Leu Ala Leu Gly Leu His Cys
                 85                  90                  95

Met His Val Lys Pro Tyr Arg Ser Gln Gln Arg Pro Met Glu Arg Glu
            100                 105                 110

Cys Xaa Ala Leu Ala Ala Gln Gly Pro Thr Arg Phe Thr Arg Ile Val
        115                 120                 125

Leu Leu Pro Gly Gln Pro Leu Ala Thr Ala Pro Pro Ala Ala Val Ala
    130                 135                 140

Glu Arg Ala Ser Ser Leu 
145                 150



<210> 2171
<211> 191
<212> PRT
<213> Homo sapiens

<400> 2171
Met Thr Cys Val Glu Lys Ala Gly Thr Asp Glu Lys Met Leu Met Lys
  1               5                  10                  15

Val Phe Arg Cys Leu Gly Ser Trp Phe Asn Leu Gly Val Leu Asp Ser
             20                  25                  30

Asn Phe Met Ala Asn Asn Lys Leu Leu Ala Leu Leu Phe Glu Val Leu
         35                  40                  45

Gln Gln Asp Lys Thr Ser Ser Asn Leu His Glu Ala Ala Ser Asp Cys
     50                  55                  60

Val Cys Ser Ala Leu Tyr Ala Ile Glu Asn Val Glu Thr Asn Leu Pro
 65                  70                  75                  80

Leu Ala Met Gln Leu Phe Gln Gly Val Leu Thr Leu Glu Thr Ala Tyr
                 85                  90                  95

His Met Ala Val Ala Arg Glu Asp Leu Asp Lys Val Leu Asn Tyr Cys
            100                 105                 110

Arg Ile Phe Thr Glu Leu Cys Glu Thr Phe Leu Glu Lys Ile Val Cys
        115                 120                 125

Thr Pro Gly Gln Gly Leu Gly Asp Leu Arg Thr Leu Glu Leu Leu Leu
    130                 135                 140

Ile Cys Ala Gly His Pro Gln Tyr Glu Val Val Phe Met Leu Phe Lys
145                 150                 155                 160

Gly His Tyr Ser Pro Ser Cys Val Leu His Ile Ile Tyr Ile Ser Leu
                165                 170                 175

Pro Arg Ala Gln Ile Phe Ile Val Glu Lys Leu Gln Ser Cys Phe 
            180                 185                 190



<210> 2172
<211> 591
<212> PRT
<213> Homo sapiens

<400> 2172
Met Leu Ala Leu Gly Ser Val Lys Ala Ile Ile Thr Asp Ser Val Lys
  1               5                  10                  15

Asn Gly Arg Ile His Phe Asp Met His Gly Phe Leu Thr Asn Val Ile
             20                  25                  30

Leu Ala Asp Leu Asn Leu Ser Val Ser Pro Phe Leu Leu Gly Arg Ala
         35                  40                  45

Leu Trp Ala Ala Ser Arg Phe Thr Val Ala Met Ser Pro Glu Leu Ile
     50                  55                  60

Gln Gln Phe Leu Gln Ala Thr Val Ser Gly Leu His Glu Thr Gln Pro
 65                  70                  75                  80

Pro Ser Val Arg Ile Ser Ala Val Arg Ala Ile Trp Gly Tyr Cys Asp
                 85                  90                  95

Gln Leu Lys Val Ser Glu Ser Thr His Val Leu Gln Pro Phe Leu Pro
            100                 105                 110

Ser Ile Leu Asp Gly Leu Ile His Leu Ala Ala Gln Phe Ser Ser Glu
        115                 120                 125

Val Leu Asn Leu Val Met Glu Thr Leu Cys Ile Val Cys Thr Val Asp
    130                 135                 140

Pro Glu Phe Thr Ala Ser Met Glu Ser Lys Ile Cys Pro Phe Thr Ile
145                 150                 155                 160

Ala Ile Phe Leu Lys Tyr Ser Asn Asp Pro Val Val Ala Ser Leu Ala
                165                 170                 175

Gln Asp Ile Phe Lys Glu Leu Ser Gln Ile Glu Ala Cys Gln Gly Pro
            180                 185                 190

Met Gln Met Arg Leu Ile Pro Thr Leu Val Ser Ile Met Gln Ala Pro
        195                 200                 205

Ala Asp Lys Ile Pro Ala Gly Leu Cys Ala Thr Ala Ile Asp Ile Leu
    210                 215                 220

Thr Thr Val Val Arg Asn Thr Lys Pro Pro Leu Ser Gln Leu Leu Ile
225                 230                 235                 240

Cys Gln Ala Phe Pro Ala Val Ala Gln Cys Thr Leu His Thr Asp Asp
                245                 250                 255

Asn Ala Thr Met Gln Asn Gly Gly Glu Cys Leu Arg Ala Tyr Val Ser
            260                 265                 270

Val Thr Leu Glu Gln Val Ala Gln Trp His Asp Glu Gln Gly His Asn
        275                 280                 285

Gly Leu Trp Tyr Val Met Gln Val Val Ser Gln Leu Leu Asp Pro Arg
    290                 295                 300

Thr Ser Glu Phe Thr Ala Ala Phe Val Gly Arg Leu Val Ser Thr Leu
305                 310                 315                 320

Ile Ser Lys Ala Gly Arg Glu Leu Gly Glu Asn Leu Asp Gln Ile Leu
                325                 330                 335

Arg Ala Ile Leu Ser Lys Met Gln Gln Ala Glu Thr Leu Ser Val Met
            340                 345                 350

Gln Ser Leu Ile Met Val Phe Ala His Leu Val His Thr Gln Leu Glu
        355                 360                 365

Pro Leu Leu Glu Phe Leu Cys Ser Leu Pro Gly Pro Thr Gly Lys Pro
    370                 375                 380

Ala Leu Glu Phe Val Met Ala Glu Trp Thr Ser Arg Gln His Leu Phe
385                 390                 395                 400

Tyr Gly Gln Tyr Glu Gly Lys Val Ser Ser Val Ala Leu Cys Lys Leu
                405                 410                 415

Leu Gln His Gly Ile Asn Ala Asp Asp Lys Arg Leu Gln Asp Ile Arg
            420                 425                 430

Val Lys Gly Glu Glu Ile Tyr Ser Met Asp Glu Gly Ile Arg Thr Arg
        435                 440                 445

Ser Lys Ser Ala Lys Asn Pro Glu Arg Trp Thr Asn Ile Pro Leu Leu
    450                 455                 460

Val Lys Ile Leu Lys Leu Ile Ile Asn Glu Leu Ser Asn Val Met Glu
465                 470                 475                 480

Ala Asn Ala Ala Arg Gln Ala Thr Pro Ala Glu Trp Ser Gln Asp Asp
                485                 490                 495

Ser Asn Asp Met Trp Glu Asp Gln Glu Glu Glu Glu Glu Glu Glu Glu
            500                 505                 510

Asp Gly Leu Ala Gly Gln Leu Leu Ser Asp Ile Leu Ala Thr Ser Lys
        515                 520                 525

Tyr Glu Glu Asp Tyr Tyr Glu Asp Asp Glu Glu Asp Asp Pro Asp Ala
    530                 535                 540

Leu Lys Asp Pro Leu Tyr Gln Ile Asp Leu Gln Ala Tyr Leu Thr Asp
545                 550                 555                 560

Phe Leu Cys Gln Phe Ala Gln Gln Pro Cys Tyr Ile Met Phe Ser Gly
                565                 570                 575

His Leu Asn Asp Asn Glu Arg Arg Val Leu Gln Thr Ile Gly Ile 
            580                 585                 590



<210> 2173
<211> 252
<212> PRT
<213> Homo sapiens

<400> 2173
Met Leu Ala Asn Asn Glu Thr Gly Ile Val Met Pro Val Pro Glu Ile
  1               5                  10                  15

Ser Gln Arg Ile Lys Ala Leu Asn Gln Glu Arg Val Ala Ala Gly Leu
             20                  25                  30

Pro Pro Ile Leu Val His Thr Asp Ala Ala Gln Ala Leu Gly Lys Gln
         35                  40                  45

Arg Val Asp Val Glu Asp Leu Gly Val Asp Phe Leu Thr Ile Val Gly
     50                  55                  60

His Lys Phe Tyr Gly Pro Arg Ile Gly Ala Leu Tyr Ile Arg Gly Leu
 65                  70                  75                  80

Gly Glu Phe Thr Pro Leu Tyr Pro Met Leu Phe Gly Gly Gly Gln Glu
                 85                  90                  95

Arg Asn Phe Arg Pro Gly Thr Glu Asn Thr Pro Met Ile Ala Gly Leu
            100                 105                 110

Gly Lys Ala Ala Glu Leu Val Thr Gln Asn Cys Glu Ala Tyr Glu Ala
        115                 120                 125

His Met Arg Asp Val Arg Asp Tyr Leu Glu Glu Arg Leu Glu Ala Glu
    130                 135                 140

Phe Gly Gln Lys Arg Ile His Leu Asn Ser Gln Phe Pro Gly Thr Gln
145                 150                 155                 160

Arg Leu Pro Asn Thr Cys Asn Phe Ser Ile Arg Gly Pro Arg Leu Gln
                165                 170                 175

Gly His Val Val Leu Ala Gln Cys Arg Val Leu Met Ala Ser Val Gly
            180                 185                 190

Ala Ala Cys His Ser Asp His Gly Asp Gln Pro Ser Pro Val Leu Leu
        195                 200                 205

Ser Tyr Gly Val Pro Phe Asp Val Ala Arg Asn Ala Leu Arg Leu Ser
    210                 215                 220

Val Gly Arg Ser Thr Thr Arg Ala Glu Val Asp Leu Val Val Gln Asp
225                 230                 235                 240

Leu Lys Gln Ala Val Ala Gln Leu Glu Asp Gln Ala 
                245                 250



<210> 2174
<211> 165
<212> PRT
<213> Homo sapiens

<400> 2174
Met Thr Arg Leu Cys Leu Pro Arg Pro Glu Ala Arg Glu Asp Pro Ile
  1               5                  10                  15

Pro Val Pro Pro Arg Gly Leu Gly Ala Gly Glu Gly Ser Gly Ser Pro
             20                  25                  30

Val Arg Pro Pro Val Ser Thr Trp Gly Pro Ser Trp Ala Gln Leu Leu
         35                  40                  45

Asp Ser Val Leu Trp Leu Gly Ala Leu Gly Leu Thr Ile Gln Ala Val
     50                  55                  60

Phe Ser Thr Thr Gly Pro Ala Leu Leu Leu Leu Leu Val Ser Phe Leu
 65                  70                  75                  80

Thr Phe Asp Leu Leu His Arg Pro Ala Gly His Thr Leu Pro Gln Arg
                 85                  90                  95

Lys Leu Leu Thr Arg Gly Gln Ser Gln Gly Ala Gly Glu Gly Pro Gly
            100                 105                 110

Gln Gln Glu Ala Leu Leu Leu Gln Met Gly Thr Val Ser Gly Gln Leu
        115                 120                 125

Ser Leu Gln Asp Ala Leu Leu Leu Leu Leu Met Gly Leu Gly Pro Leu
    130                 135                 140

Leu Arg Ala Cys Gly Met Pro Leu Thr Leu Leu Gly Leu Ala Phe Cys
145                 150                 155                 160

Leu His Pro Trp Ala 
                165



<210> 2175
<211> 394
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (389)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (393)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2175
Met Ala Thr Ser Lys Leu Pro Val Val Pro Gly Glu Glu Glu Asn Thr
  1               5                  10                  15

Ile Leu Met Ala Lys Glu Arg Leu Glu Ala Leu Arg Thr Ala Phe Glu
             20                  25                  30

Ser Gly Asp Leu Pro Gln Ala Ala Ser His Leu Gln Glu Leu Leu Ala
         35                  40                  45

Ser Thr Glu Ser Ile Arg Leu Glu Val Gly Val Thr Gly Glu Ser Gly
     50                  55                  60

Ala Gly Lys Ser Ser Leu Ile Asn Ala Leu Arg Gly Leu Glu Ala Glu
 65                  70                  75                  80

Asp Pro Gly Ala Ala Leu Thr Gly Val Met Glu Thr Thr Met Gln Pro
                 85                  90                  95

Ser Pro Tyr Pro His Pro Gln Phe Pro Asp Val Thr Leu Trp Asp Leu
            100                 105                 110

Pro Gly Ala Gly Ser Pro Gly Cys Pro Ala Asp Lys Tyr Leu Lys Gln
        115                 120                 125

Val Asp Phe Ser Arg Tyr Asp Phe Phe Leu Leu Val Ser Pro Arg Arg
    130                 135                 140

Cys Gly Ala Val Glu Thr Arg Leu Ala Ala Glu Ile Leu Cys Gln Gly
145                 150                 155                 160

Lys Lys Phe Tyr Phe Val Arg Thr Lys Val Asp Glu Asp Leu Ala Ala
                165                 170                 175

Thr Arg Thr Gln Arg Pro Ser Gly Phe Arg Glu Ala Ala Val Leu Gln
            180                 185                 190

Glu Ile Arg Asp His Cys Ala Glu Arg Leu Arg Glu Ala Gly Val Ala
        195                 200                 205

Asp Pro Arg Ile Phe Leu Val Ser Asn Leu Ser Pro Ala Arg Tyr Asp
    210                 215                 220

Phe Pro Thr Leu Val Ser Thr Trp Glu His Asp Leu Pro Ser His Arg
225                 230                 235                 240

Arg His Ala Gly Leu Leu Ser Leu Pro Asp Ile Ser Leu Glu Ala Leu
                245                 250                 255

Gln Lys Lys Lys Ala Met Leu Gln Glu Gln Val Leu Lys Thr Ala Leu
            260                 265                 270

Val Leu Gly Val Ile Gln Ala Leu Pro Val Pro Gly Leu Ala Ala Ala
        275                 280                 285

Tyr Asp Asp Ala Leu Leu Ile His Ser Leu Arg Gly Tyr His Arg Ser
    290                 295                 300

Phe Gly Leu Asp Asp Asp Ser Leu Ala Lys Leu Ala Glu Gln Val Gly
305                 310                 315                 320

Lys Gln Ala Gly Asp Leu Arg Ser Val Ile Arg Ser Pro Leu Ala Asn
                325                 330                 335

Glu Val Ser Pro Glu Thr Val Leu Arg Leu Tyr Ser Gln Ser Ser Asp
            340                 345                 350

Gly Ala Met Arg Val Ala Arg Ala Phe Glu Arg Gly Ile Pro Val Phe
        355                 360                 365

Gly Thr Leu Val Ala Gly Gly Ile Ser Phe Trp Arg Cys Leu His His
    370                 375                 380

Ala Pro Arg Leu Xaa Gln Arg Arg Xaa Ala 
385                 390



<210> 2176
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (49)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2176
Met Cys Arg Ser Trp Arg Ala Thr Ser Thr Gly Cys Trp Cys Gly Ser
  1               5                  10                  15

Trp Arg Pro His Pro Arg Cys Cys Arg Ser Pro Arg Ala Pro Pro Asn
             20                  25                  30

Ser Leu Pro His Pro Thr Pro Arg Arg Val Gly Met Asp Leu Leu Leu
         35                  40                  45

Xaa Ala Leu Ser Pro Pro Glu Leu Ser His Leu Gln Trp Gly Ile Val
     50                  55                  60

Cys Leu Ala Leu Ser Leu Leu Ala Pro Leu Pro Pro Ala Ser Thr Gly
 65                  70                  75                  80

Ala Ala Gly Arg Gly Pro Ser Gly Phe Pro Leu Glu Ala Ser Gly Ser
                 85                  90                  95

Val His Asn Leu Cys Val Phe Gly Ser Pro Gly Ser Phe Pro Pro Ala
            100                 105                 110

Xaa Phe His Ile Pro Xaa Leu Trp Gly Pro Gln Gly Ile Gly Thr Leu
        115                 120                 125

Pro Gln Asp Arg Ala Gly Val Asn Cys Ser Leu Met Gln 
    130                 135                 140



<210> 2177
<211> 316
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (267)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (274)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (281)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (285)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (288)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (290)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (315)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2177
Met Ala Val Ala Pro Ser Cys Leu Pro Ala Ser Gln Glu Pro Ile Ser
  1               5                  10                  15

Leu Ala Ser Cys Ala Met Ala Asp Leu Val Pro Asp Leu Gln Pro Ile
             20                  25                  30

Leu Phe Trp Met Ser Asn Ser Ile Glu Leu Leu Tyr Phe Ile Gln Gln
         35                  40                  45

Lys Cys Pro Leu Tyr Met Gln Ser Met Glu Glu Gln Leu Asp Ile Thr
     50                  55                  60

Gly Ser Lys Glu Ser Leu Phe Ser Cys Thr Leu Thr Ala Ser Glu Glu
 65                  70                  75                  80

Ala Met Ala Val Leu Glu Glu Val Val Leu Tyr Ala Phe Gln Gln Cys
                 85                  90                  95

Val Tyr Tyr Val Ser Lys Ser Leu Tyr Ile Cys Leu Pro Ala Leu Leu
            100                 105                 110

Glu Cys Pro Pro Phe Gln Thr Glu Arg Arg Glu Ser Trp Ser Ser Ala
        115                 120                 125

Pro Glu Leu Pro Glu Glu Leu Arg Arg Val Val Ser Val Tyr Gln Ala
    130                 135                 140

Ala Leu Asp Leu Leu Arg Gln Leu Gln Val His Pro Glu Val Ala Ser
145                 150                 155                 160

Gln Met Leu Ala Xaa Leu Phe Phe Phe Ser Gly Thr Leu Leu Leu Asn
                165                 170                 175

Gln Leu Leu Asp Arg Gly Pro Ser Leu Ser Cys Phe His Trp Pro Arg
            180                 185                 190

Gly Val Gln Ala Cys Ala Arg Leu Gln Gln Leu Leu Glu Trp Met Arg
        195                 200                 205

Ser Ala Gly Phe Gly Ala Ala Gly Glu His Phe Phe Gln Lys Leu Ser
    210                 215                 220

Cys Thr Leu Asn Leu Leu Ala Thr Pro Arg Ala Xaa Leu Ile Gln Met
225                 230                 235                 240

Ser Trp Thr Ala Leu Arg Ala Ala Phe Pro Ala Leu Ser Pro Ala Gln
                245                 250                 255

Leu His Arg Leu Leu Thr His Tyr Gln Leu Xaa Ser Ala Met Gly Pro
            260                 265                 270

Met Xaa Thr Trp Glu Pro Gly Ala Xaa Asp Ser Pro Xaa Ala Phe Xaa
        275                 280                 285

Ser Xaa Asp Val Leu Glu Ser Tyr Glu Asn Pro Pro Pro Ile Val Leu
    290                 295                 300

Pro Ser Asp Gly Phe Gln Val Asp Leu Glu Xaa Asn 
305                 310                 315



<210> 2178
<211> 140
<212> PRT
<213> Homo sapiens

<400> 2178
Met Gln Pro Arg His Leu Leu Gln His Pro Leu Pro Asp His Ala Gly
  1               5                  10                  15

Gly Asp Cys Gly Val His Gly Ala Gly Gly Gly Cys Arg Arg Gly Gly
             20                  25                  30

His Gly Asp Gly Thr Ala Asp Ser Val Arg Arg Gly Arg Val Ala Ala
         35                  40                  45

Gly Pro Asp His Glu Arg Leu Pro Leu Pro Arg Arg Thr Ala Ala Ala
     50                  55                  60

Asp Arg Leu Asp Arg Leu His Arg Glu Glu Cys Val Glu Glu Gln Arg
 65                  70                  75                  80

Leu Leu Leu Leu Val Leu Phe Phe Trp Val Ala Gly Leu Thr Leu Leu
                 85                  90                  95

Asn Ser Arg Gly Leu Leu Leu Ser Ala Gly Arg His Asp His Ala Glu
            100                 105                 110

His Arg Arg His Gln Trp Ile Pro Arg Val Ser Val Thr Ala Ala Cys
        115                 120                 125

Leu Gly Gln Asn Lys Gly Thr Ala Phe Phe Ser Lys 
    130                 135                 140



<210> 2179
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2179
Met Ser Thr Ser Ala Ser Ala Leu Leu Ala Cys Val Arg Glu Val Lys
  1               5                  10                  15

Val Ala Pro Ser Glu Leu Ala Arg Ser Arg Cys Ala Leu Phe Ser Gly
             20                  25                  30

Pro Leu Val Gln Ala Val Ser Ala Leu Val Gly Phe Ala Thr Glu Pro
         35                  40                  45

Gln Phe Leu Gly Arg Ala Ala Ala Val Ser Ala Glu Gly Lys Ala Val
     50                  55                  60

Gln Thr Ala Ile Leu Gly Gly Ala Met Ser Val Val Ser Ala Cys Val
 65                  70                  75                  80

Leu Leu Thr Gln Cys Leu Arg Asp Leu Ala Xaa Thr Pro Thr Gly Arg
                 85                  90                  95

Gln Asp Val Gly Pro Gln Gly Glu Ala Glu Glu Leu Gly Leu Arg Arg
            100                 105                 110

Val 




<210> 2180
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2180
Met Thr Asp Gln Thr Tyr Cys Asp Arg Leu Val Gln Asp Thr Pro Phe
  1               5                  10                  15

Leu Thr Gly His Gly Arg Leu Ser Glu Gln Gln Val Asp Arg Ile Ile
             20                  25                  30

Leu Gln Leu Asn Arg Tyr Tyr Pro Gln Ile Leu Thr Asn Lys Glu Ala
         35                  40                  45

Glu Lys Phe Arg Asn Pro Lys Ala Ser Leu Arg Val Arg Leu Cys Asp
     50                  55                  60

Leu Leu Ser His Leu Gln Arg Ser Xaa Glu Arg Asp Cys Gln Glu Phe
 65                  70                  75                  80

Tyr Arg Ala Leu Tyr Ile His Ala Gln Pro Leu His Ser Arg Leu Pro
                 85                  90                  95

Ser Arg His Ala Leu Gln Asn Ser Asp Cys Thr Glu Leu Asp Ser Gly
            100                 105                 110

Ser Gln Ser Gly Glu Leu Ser Asn Arg Gly Pro Met Ser Phe Leu Ala
        115                 120                 125

Gly Leu Gly Leu Ala Val Gly Leu Ala Leu Leu Leu Tyr Cys Tyr Pro
    130                 135                 140

Pro Asp Pro Lys Gly Leu Pro Gly Thr Arg Arg Val Leu Gly Phe Ser
145                 150                 155                 160

Pro Val Ile Ile Asp Arg His Val Ser Arg Tyr Leu Leu Ala Phe Leu
                165                 170                 175

Ala Asp Asp Leu Gly Gly Leu 
            180



<210> 2181
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2181
Met Met Lys Thr Cys Ser Ser Pro Tyr Trp Xaa Val Ile Ser Val Leu
  1               5                  10                  15

Gly Glu Ala Arg Pro Asp Ser Ser Lys Ala Ser Ser Leu Gly Ser Pro
             20                  25                  30

Ser Asn Gly Ala Ser Gly Arg Ala Gly Ser Pro Cys Gln Asn Pro Ile
         35                  40                  45

Leu Ala Leu Gln Lys Asp Trp Thr Ser Val Ser Leu Gln Trp Glu Ala
     50                  55                  60

Thr Leu Asp Thr Arg Ser His Ser Gly Gly His Lys Ala Thr Leu Leu
 65                  70                  75                  80

Ala Leu Asp Leu Glu Glu Leu Ser His Ala Gly Glu Ile Leu Leu Val
                 85                  90                  95

Gly Leu Ser His Leu Leu Leu Cys Arg Leu Trp Val His Asn Leu Gln
            100                 105                 110

Ala Leu Glu Trp Gly Glu Gly His Ala Gly Gly Arg Ala Arg Gly Ala
        115                 120                 125

Val Ala Asp Gly Gly Leu Pro Ala Ile Tyr Asp Ala Leu Leu Leu Gln
    130                 135                 140

Gly Arg Cys Ser Val Leu Glu Ile Leu Ala Leu Val Ala Ser Phe Thr
145                 150                 155                 160

Cys Val Cys Arg Thr Arg Pro Leu Pro Asp Leu Pro Arg Trp Pro Arg
                165                 170                 175

Leu Asn Pro Arg Ser Ser Trp 
            180



<210> 2182
<211> 119
<212> PRT
<213> Homo sapiens

<400> 2182
Met Ser His Leu Gly Trp Pro Phe Leu Val Lys Asp Gly Leu Phe Lys
  1               5                  10                  15

Ser Cys Asn Ile Phe Leu Leu Gly Ser Asn Leu Phe His Asp Leu Gly
             20                  25                  30

Gln Met Ile Ser Gln Leu Val Pro Gly Ile Leu Cys Ile Leu Gln Pro
         35                  40                  45

Ile Leu Glu Cys Arg Val His His Ile Thr Leu Leu Ala Gln Ile Ile
     50                  55                  60

Gly Cys Leu Gly Gln Asp Ser Ile His Gln Gly Phe Gln His Gln Gly
 65                  70                  75                  80

Val Val Pro Leu Leu Val Ser Leu Leu His Ile Gly Ala Gly Glu Val
                 85                  90                  95

Gln Pro Val Phe Gln Thr His Gly Val Trp Leu Asn Pro His Gly Val
            100                 105                 110

Leu Arg Ile Ser Asp Val Trp 
        115



<210> 2183
<211> 330
<212> PRT
<213> Homo sapiens

<400> 2183
Met Phe Ala Ser Pro Arg Arg Trp Ser Ser Arg Arg Pro Ser Leu Ala
  1               5                  10                  15

Ser Gly His Ser Tyr Leu Pro Ser Ser Ala Cys Tyr His Ser Ala Ser
             20                  25                  30

Pro Gln His Pro Cys Ser Ala Thr Thr Gly Leu Trp Ala His Arg Arg
         35                  40                  45

Cys Pro Ser Pro Cys Ala Arg Lys Val Trp Gln Pro Ser Ala Leu Thr
     50                  55                  60

Cys Gln Cys Pro Trp Met Glu Ile Pro Thr His Pro Pro Arg Arg Trp
 65                  70                  75                  80

Tyr Asn Thr Thr Gly Arg Leu Gly Met Thr Gly Ser Pro Ser Gly Ala
                 85                  90                  95

Ser Gly Val Ala Cys Gly Tyr Pro Val Arg Lys Leu Trp Lys Asn Gln
            100                 105                 110

Gly Arg Gly Ala Glu Val Ser Leu Asn Leu His His Gln Pro Arg Glu
        115                 120                 125

Lys Ile Leu Trp Leu Ser Leu Gly Thr Gln Ile Thr Tyr Ile Gly Leu
    130                 135                 140

Gln Phe Ile Ser Phe Leu Leu Leu Leu Thr Asp Leu Leu Leu Thr Gly
145                 150                 155                 160

Asn Pro Ala Cys Gly Leu Lys Leu Ser Ala Phe Ala Ala Val Ser Ser
                165                 170                 175

Val Leu Ser Gly Leu Leu Gly Met Val Ala His Met Met Tyr Ser Gln
            180                 185                 190

Val Phe Gln Ala Thr Val Asn Leu Gly Pro Glu Asp Trp Arg Pro His
        195                 200                 205

Val Trp Asn Tyr Gly Trp Ala Phe Tyr Met Ala Trp Leu Ser Phe Thr
    210                 215                 220

Cys Cys Met Ala Ser Ala Val Thr Thr Phe Asn Thr Tyr Thr Arg Met
225                 230                 235                 240

Val Leu Glu Phe Lys Cys Lys His Ser Lys Ser Phe Lys Glu Asn Pro
                245                 250                 255

Asn Cys Leu Pro His His His Gln Cys Phe Pro Arg Arg Leu Ser Ser
            260                 265                 270

Ala Ala Pro Thr Val Gly Pro Leu Thr Ser Tyr His Gln Tyr His Asn
        275                 280                 285

Gln Pro Ile His Ser Val Ser Glu Gly Val Asp Phe Tyr Ser Glu Leu
    290                 295                 300

Arg Asn Lys Gly Phe Gln Arg Gly Ala Ser Gln Glu Leu Lys Glu Ala
305                 310                 315                 320

Val Arg Ser Ser Val Glu Glu Glu Gln Cys 
                325                 330



<210> 2184
<211> 604
<212> PRT
<213> Homo sapiens

<400> 2184
Met Asn Thr Lys Arg Asp Phe Glu Ser Lys Ala Asn His Leu Gly Asp
  1               5                  10                  15

Ser Gly Gly Thr Pro Val Lys Thr Arg Arg His Ser Trp Arg Gln Gln
             20                  25                  30

Ile Phe Leu Arg Val Ala Thr Pro Gln Lys Ala Cys Asp Ser Ser Ser
         35                  40                  45

Arg Tyr Glu Asp Tyr Ser Glu Leu Gly Glu Leu Pro Pro Arg Ser Pro
     50                  55                  60

Leu Glu Pro Val Cys Glu Asp Gly Pro Phe Gly Pro Pro Pro Glu Glu
 65                  70                  75                  80

Lys Lys Arg Thr Ser Arg Glu Leu Arg Glu Leu Trp Gln Lys Ala Ile
                 85                  90                  95

Leu Gln Gln Ile Leu Leu Leu Arg Met Glu Lys Glu Asn Gln Lys Leu
            100                 105                 110

Gln Ala Ser Glu Asn Asp Leu Leu Asn Lys Arg Leu Lys Leu Asp Tyr
        115                 120                 125

Glu Glu Ile Thr Pro Cys Leu Lys Glu Val Thr Thr Val Trp Glu Lys
    130                 135                 140

Met Leu Ser Thr Pro Gly Arg Ser Lys Ile Lys Phe Asp Met Glu Lys
145                 150                 155                 160

Met His Ser Ala Val Gly Gln Gly Val Pro Arg His His Arg Gly Glu
                165                 170                 175

Ile Trp Lys Phe Leu Ala Glu Gln Phe His Leu Lys His Gln Phe Pro
            180                 185                 190

Ser Lys Gln Gln Pro Lys Asp Val Pro Tyr Lys Glu Leu Leu Lys Gln
        195                 200                 205

Leu Thr Ser Gln Gln His Ala Ile Leu Ile Asp Leu Gly Arg Thr Phe
    210                 215                 220

Pro Thr His Pro Tyr Phe Ser Ala Gln Leu Gly Ala Gly Gln Leu Ser
225                 230                 235                 240

Leu Tyr Asn Ile Leu Lys Ala Tyr Ser Leu Leu Asp Gln Glu Val Gly
                245                 250                 255

Tyr Cys Gln Gly Leu Ser Phe Val Ala Gly Ile Leu Leu Leu His Met
            260                 265                 270

Ser Glu Glu Glu Ala Phe Lys Met Leu Lys Phe Leu Met Phe Asp Met
        275                 280                 285

Gly Leu Arg Lys Gln Tyr Arg Pro Asp Met Ile Ile Leu Gln Ile Gln
    290                 295                 300

Met Tyr Gln Leu Ser Arg Leu Leu His Asp Tyr His Arg Asp Leu Tyr
305                 310                 315                 320

Asn His Leu Glu Glu His Glu Ile Gly Pro Ser Leu Tyr Ala Ala Pro
                325                 330                 335

Trp Phe Leu Thr Met Phe Ala Ser Gln Phe Pro Leu Gly Phe Val Ala
            340                 345                 350

Arg Val Phe Asp Met Ile Phe Leu Gln Gly Thr Glu Val Ile Phe Lys
        355                 360                 365

Val Ala Leu Ser Leu Leu Gly Ser His Lys Pro Leu Ile Leu Gln His
    370                 375                 380

Glu Asn Leu Glu Thr Ile Val Asp Phe Ile Lys Ser Thr Leu Pro Asn
385                 390                 395                 400

Leu Gly Leu Val Gln Met Glu Lys Thr Ile Asn Gln Val Phe Glu Met
                405                 410                 415

Asp Ile Ala Lys Gln Leu Gln Ala Tyr Glu Val Glu Tyr His Val Leu
            420                 425                 430

Gln Glu Glu Leu Ile Asp Ser Ser Pro Leu Ser Asp Asn Gln Arg Met
        435                 440                 445

Asp Lys Leu Glu Lys Thr Asn Ser Ser Leu Arg Lys Gln Asn Leu Asp
    450                 455                 460

Leu Leu Glu Gln Leu Gln Val Ala Asn Gly Arg Ile Gln Ser Leu Glu
465                 470                 475                 480

Ala Thr Ile Glu Lys Leu Leu Ser Ser Glu Ser Lys Leu Lys Gln Ala
                485                 490                 495

Met Leu Thr Leu Glu Leu Glu Arg Ser Ala Leu Leu Gln Thr Val Glu
            500                 505                 510

Glu Leu Arg Arg Arg Ser Ala Glu Pro Ser Asp Arg Glu Pro Glu Cys
        515                 520                 525

Thr Gln Pro Glu Pro Arg Ala Thr Asp Ser Ser Ala Gly Glu Ile Ala
    530                 535                 540

Thr Pro Ser His Thr Val Gln Ala Leu Thr Glu Arg Asp Arg Arg Arg
545                 550                 555                 560

Trp Lys Glu Arg Arg Lys Arg Glu Val Cys Phe Ser Gly Arg Lys Pro
                565                 570                 575

Ala Cys Gln Gln Val Asp Ser Tyr Glu Leu Gln Leu Ala Ile Gln Gly
            580                 585                 590

Ala Cys Pro Ser Val Phe Phe Val Val Phe Arg Tyr 
        595                 600



<210> 2185
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2185
Met Ser Gly Lys Thr Lys Ala Arg Arg Ala Ala Met Phe Phe Arg Arg
  1               5                  10                  15

Cys Ser Glu Asp Ala Ser Gly Ser Ala Ser Gly Asn Ala Leu Leu Ser
             20                  25                  30

Glu Asp Glu Asn Pro Asp Ala Asn Gly Val Thr Arg Ser Trp Lys Ile
         35                  40                  45

Ile Leu Ser Thr Met Leu Thr Leu Thr Phe Leu Leu Val Gly Leu Leu
     50                  55                  60

Asn His Gln Trp Leu Lys Glu Thr Asp Val Pro Gln Lys Ser Arg Gln
 65                  70                  75                  80

Leu Tyr Ala Ile Ile Ala Glu Tyr Gly Ser Arg Leu Tyr Lys Tyr Gln
                 85                  90                  95

Ala Arg Leu Arg Met Pro Lys Glu Gln Leu Glu Leu Leu Lys Lys Glu
            100                 105                 110

Ser Gln Asn Leu Glu Asn Asn Phe Arg Gln Xaa Leu Phe Leu Ile Glu
        115                 120                 125

Gln Ile Xaa 
    130



<210> 2186
<211> 122
<212> PRT
<213> Homo sapiens

<400> 2186
Met His Val Glu Ser Ser Ala Glu Pro Gly Lys Ala Pro Lys His Ala
  1               5                  10                  15

Gly Gln Lys Lys Thr Tyr Arg Ala Ile Ala Glu Thr Tyr Ala Phe Leu
             20                  25                  30

Pro Arg Glu Ala Val Thr Arg Phe Leu Met Ser Cys Thr Glu Cys Gln
         35                  40                  45

Lys Arg Met His Phe Asn Ser Asn Gly Leu Glu Pro Lys Glu Asn Glu
     50                  55                  60

Pro Pro Ser Pro Leu Val Ser Gly Ile Ile Asp Tyr Asn Met Pro Leu
 65                  70                  75                  80

Thr Ser Thr Tyr Leu Lys Gln Met Lys Leu Arg Val Met Asn Ser Gln
                 85                  90                  95

Glu Gln Pro Ser Ser Leu Ser Pro Ala Pro Gly Phe Val Asn Thr Val
            100                 105                 110

Ile Thr Val Leu Ile Cys Ala His Glu Glu 
        115                 120



<210> 2187
<211> 173
<212> PRT
<213> Homo sapiens

<400> 2187
Met Ser Ser Ser Arg Cys Pro Ile Phe Tyr Trp Leu His Gln Trp Leu
  1               5                  10                  15

Tyr Trp Leu Pro Gly Asn Leu Asp Ile Arg Asp His Ser Pro Leu Ala
             20                  25                  30

Leu Leu Thr Leu Gly Leu Gln Arg Ser Lys Asn Asn Lys Thr Leu Glu
         35                  40                  45

Lys Pro Asp Leu Gly Phe Leu Ser Pro Gln Val Phe Val Tyr Val Val
     50                  55                  60

His Ala Ala Val Leu Leu Leu Phe Gly Gly Leu Cys Met His Val Gln
 65                  70                  75                  80

Val Leu Thr Arg Phe Leu Gly Ser Ser Thr Pro Ile Met Tyr Trp Phe
                 85                  90                  95

Pro Ala His Leu Leu Gln Asp Gln Glu Pro Leu Leu Arg Ser Leu Lys
            100                 105                 110

Thr Val Pro Trp Lys Pro Leu Ala Glu Asp Ser Pro Pro Gly Gln Lys
        115                 120                 125

Val Pro Arg Asn Pro Ile Met Gly Leu Leu Tyr His Trp Lys Thr Cys
    130                 135                 140

Ser Pro Val Thr Arg Tyr Ile Leu Gly Tyr Phe Leu Thr Tyr Trp Leu
145                 150                 155                 160

Leu Gly Leu Leu Leu His Cys Asn Phe Leu Pro Trp Thr 
                165                 170



<210> 2188
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (65)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2188
Met Lys Asp Ala Glu Thr Asn Trp Pro Ser Tyr Ile Lys Tyr Ser Glu
  1               5                  10                  15

His Phe Ile Asn Thr Cys Gln Ser Tyr Pro Gly Lys His Ile Phe Ile
             20                  25                  30

Phe Gln Ile Met Trp Leu Gly Tyr Leu Val Xaa Leu Asn Phe Gly Tyr
         35                  40                  45

Val Cys Leu Phe Pro Arg Xaa Arg Asn Ile His Tyr Leu Phe Asn Thr
     50                  55                  60

Xaa Leu Phe Leu Ile Ala Trp Xaa Leu Leu Ile Ala Arg Ser Gln Xaa
 65                  70                  75                  80

Ala Arg Asn Val Trp Phe Phe Ile Val Ser Phe Cys Tyr Lys Phe Leu
                 85                  90                  95

Ser Tyr Phe Arg Ala Ser Ser Thr Leu Lys Val 
            100                 105



<210> 2189
<211> 165
<212> PRT
<213> Homo sapiens

<400> 2189
Met Val Val Gln Gln Glu Ser Arg Asn Leu Asn Ile Ala Ile Ile Arg
  1               5                  10                  15

Pro Ser Ile Val Gly Ala Thr Trp Gln Glu Pro Phe Pro Gly Trp Val
             20                  25                  30

Asp Asn Ile Asn Gly Pro Asn Gly Ile Ile Ile Ala Thr Gly Lys Gly
         35                  40                  45

Phe Leu Arg Ala Ile Lys Ala Thr Pro Met Ala Val Ala Asp Val Ile
     50                  55                  60

Pro Val Asp Thr Val Val Asn Leu Met Leu Ala Val Gly Trp Tyr Thr
 65                  70                  75                  80

Ala Val His Arg Pro Lys Ser Thr Leu Val Tyr His Ile Thr Ser Gly
                 85                  90                  95

Asn Met Asn Pro Cys Asn Trp His Lys Met Gly Val Gln Val Leu Ala
            100                 105                 110

Thr Phe Glu Lys Ile Pro Phe Glu Arg Pro Phe Arg Arg Pro Asn Ala
        115                 120                 125

Asn Phe Thr Ser Asn Ser Phe Thr Ser Gln Tyr Trp Asn Ala Val Ser
    130                 135                 140

His Arg Ala Pro Ala Ile Ile Tyr Asp Cys Tyr Leu Arg Leu Thr Gly
145                 150                 155                 160

Lys Glu Ala Gln Gly 
                165



<210> 2190
<211> 193
<212> PRT
<213> Homo sapiens

<400> 2190
Met Asn Ile Phe Met Thr Phe Val Ile Asn Val Leu Arg Lys Asn Leu
  1               5                  10                  15

Phe His Gly Phe Met Val Ile Thr Gln Ala Pro Val Arg Ile Leu Pro
             20                  25                  30

Ser Gln Glu Arg Ile Arg Thr Pro Cys His Ser Pro Ala Ile Leu Leu
         35                  40                  45

Ser Ser Cys Arg Val Leu Ser Gly Asn Asn Cys Ile Met Ala Ala Leu
     50                  55                  60

Thr Ser Val Ile Lys Arg Asn Leu Leu Phe Phe Arg Leu Asp Leu Phe
 65                  70                  75                  80

Pro Leu Trp Leu Ile Phe Leu Tyr Ile Val Lys Met Gly Asp Phe Pro
                 85                  90                  95

Ser Ala Pro Thr His Leu Asn Thr Ala Ala Ile Cys Thr Cys Leu Leu
            100                 105                 110

Pro Ile Pro Leu Gly Thr His Ser Asp Leu Leu Ser Val Ser Cys Ser
        115                 120                 125

Trp Phe His Leu Phe Glu Lys Gly Pro Pro Leu Ser Tyr Lys His Leu
    130                 135                 140

Val Arg Gln Val His Pro Leu Met Asn Ala Asp Thr Ala Ala Gly Gly
145                 150                 155                 160

Phe Val Tyr Thr Cys Lys Asp Lys Leu Arg Ser Leu Leu Phe Gly Glu
                165                 170                 175

Val Lys Glu Asp Gly Asn Gly Cys Phe Ile Cys Met Ser Leu Glu Gln
            180                 185                 190

Cys 




<210> 2191
<211> 103
<212> PRT
<213> Homo sapiens

<400> 2191
Met Glu Thr Thr Asn Gly Thr Glu Thr Trp Tyr Glu Ser Leu His Ala
  1               5                  10                  15

Val Leu Lys Ala Leu Asn Ala Thr Leu His Ser Asn Leu Leu Cys Arg
             20                  25                  30

Pro Gly Pro Gly Leu Gly Pro Asp Asn Gln Thr Glu Glu Arg Arg Ala
         35                  40                  45

Ser Leu Pro Gly Arg Asp Asp Asn Ser Tyr Met Tyr Ile Leu Phe Val
     50                  55                  60

Met Phe Leu Phe Ala Val Thr Val Gly Ser Leu Ile Leu Gly Tyr Thr
 65                  70                  75                  80

Arg Ser Arg Lys Val Asp Lys Arg Ser Asp Pro Tyr His Val Tyr Ile
                 85                  90                  95

Lys Asn Arg Val Ser Met Ile 
            100



<210> 2192
<211> 171
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2192
Met Thr Pro Glu Phe Asp Glu Glu Val Val Phe Glu Asn Ser Pro Leu
  1               5                  10                  15

Tyr Gln Tyr Leu Gln Asp Leu Gly His Thr Asp Phe Glu Ile Cys Ser
             20                  25                  30

Ser Leu Ser Pro Lys Thr Glu Lys Cys Thr Thr Glu Gly Gln Gln Lys
         35                  40                  45

Pro Pro Thr Arg Val Leu Pro Lys Gln Gly Ile Leu Leu Lys Val Ala
     50                  55                  60

Glu Thr Ile Lys Ser Trp Ile Phe Phe Ser Gln Cys Asn Lys Lys Asp
 65                  70                  75                  80

Asp Leu Leu His Lys Leu Asp Ile Gly Phe Arg Leu Asp Ser Leu His
                 85                  90                  95

Thr Ile Leu Gln Gln Glu Val Leu Leu Gln Glu Asp Val Glu Leu Ile
            100                 105                 110

Glu Leu Leu Asp Pro Ser Ile Leu Ser Ala Gly Gln Ser Gln Gln Gln
        115                 120                 125

Glu Lys Trp Thr Pro Ser Asn Thr Cys Ser Leu Ala Thr Pro Asn Ile
    130                 135                 140

Trp Asp Leu Ser Met Leu Xaa Ala Phe Ile Ser Leu Leu Leu Cys Phe
145                 150                 155                 160

His Leu Val Asp Cys Val Ser Trp Leu Val Trp 
                165                 170



<210> 2193
<211> 187
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2193
Met Leu Lys Xaa Trp Ala Ile Lys Gln Gly Ile Leu Leu Lys Val Ala
  1               5                  10                  15

Glu Thr Ile Lys Ser Trp Ile Xaa Phe Ser Gln Cys Asn Lys Lys Asp
             20                  25                  30

Asp Leu Leu His Lys Leu Asp Ile Gly Phe Arg Leu Asp Ser Leu His
         35                  40                  45

Thr Ile Leu Gln Gln Glu Val Leu Leu Gln Glu Asp Val Glu Leu Ile
     50                  55                  60

Glu Leu Leu Asp Pro Ser Ile Leu Ser Ala Gly Gln Ser Gln Gln Gln
 65                  70                  75                  80

Glu Asn Gly His Leu Xaa Thr Leu Cys Ser Leu Ala Thr Pro Asn Ile
                 85                  90                  95

Trp Asp Leu Ser Met Leu Phe Ala Phe Ile Ser Leu Leu Val Met Leu
            100                 105                 110

Xaa Thr Trp Xaa Ile Xaa Ser Ser Trp Leu Xaa Trp Gly Val Ile Leu
        115                 120                 125

Phe Val Tyr Leu Val Ile Arg Ala Leu Arg Leu Trp Arg Thr Ala Lys
    130                 135                 140

Leu Gln Val Thr Leu Lys Lys Tyr Ser Val His Leu Glu Asp Met Ala
145                 150                 155                 160

Thr Asn Ser Arg Ala Phe Thr Asn Leu Val Arg Lys Ala Leu Pro Pro
                165                 170                 175

Cys Arg Asn Arg Leu Leu Val Met Arg Arg Lys 
            180                 185



<210> 2194
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2194
Met Gln Ser Leu Gln Pro Val Val Ser Cys Gly Trp Leu Ala Pro Pro
  1               5                  10                  15

Pro Asn Gly Gln Lys Glu Gly Asn Arg Tyr Leu Ala Gly Ser Thr Ile
             20                  25                  30

Tyr Phe His Cys Asp Asn Gly Tyr Ser Leu Ala Gly Ala Glu Thr Ser
         35                  40                  45

Thr Cys Gln Ala Asp Gly Thr Trp Ser Ser Pro Thr Pro Lys Cys Gln
     50                  55                  60

Pro Gly Arg Ser Tyr Ala Val Leu Leu Gly Ile Ile Phe Gly Gly Leu
 65                  70                  75                  80

Ala Val Val Ala Ala Val Ala Leu Val Tyr Val Leu Leu Arg Arg Xaa
                 85                  90                  95

Lys Gly Asn Thr His Val Trp Gly Ala Gln Pro 
            100                 105



<210> 2195
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2195
Met Pro Gly Leu Thr Phe Ser Asn Glu Leu Ile Ser Arg Asp Glu Gly
  1               5                  10                  15

Leu His Cys Asp Phe Ala Cys Leu Met Phe Gln Tyr Leu Val Asn Lys
             20                  25                  30

Pro Ser Glu Glu Arg Val Arg Glu Ile Ile Val Asp Ala Val Lys Ile
         35                  40                  45

Glu Gln Glu Phe Leu Thr Glu Ala Leu Pro Val Gly Leu Ile Gly Met
     50                  55                  60

Asn Cys Ile Leu Met Lys Gln Tyr Ile Glu Phe Val Ala Asp Arg Leu
 65                  70                  75                  80

Leu Val Xaa Leu Gly Phe Ser Lys Val Phe Gln Ala Glu Asn Pro Phe
                 85                  90                  95

Asp Phe Met Glu Asn Ile Ser Leu Glu Gly Lys Thr Asn Phe Phe Glu
            100                 105                 110

Lys Arg Val Ser Glu Tyr Gln Arg Phe Ala Val Met Ala Glu Thr Thr
        115                 120                 125

Asp Asn Val Phe Thr Leu Asp Ala Asp Phe 
    130                 135



<210> 2196
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2196
Met Asp Thr Ala Glu Glu Asp Ile Cys Arg Val Cys Arg Ser Glu Gly
  1               5                  10                  15

Thr Pro Glu Lys Pro Leu Tyr His Pro Cys Val Cys Thr Gly Ser Ile
             20                  25                  30

Lys Phe Ile His Gln Glu Cys Leu Val Gln Trp Leu Lys His Ser Arg
         35                  40                  45

Lys Glu Tyr Cys Glu Leu Cys Lys His Arg Phe Ala Phe Thr Pro Ile
     50                  55                  60

Tyr Ser Pro Asp Met Pro Ser Arg Leu Pro Ile Gln Asp Ile Phe Ala
 65                  70                  75                  80

Gly Leu Val Thr Ser Ile Gly Thr Ala Ile Arg Tyr Trp Phe His Tyr
                 85                  90                  95

Thr Leu Val Ala Phe Ala Trp Leu Gly Val Val Pro Leu Thr Ala Cys
            100                 105                 110

Arg Ile Tyr Lys Cys Leu Phe Thr Gly Ser Arg Xaa Leu Thr Ala Asp
        115                 120                 125

Gly Cys His 
    130



<210> 2197
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (61)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2197
Met Asp Asn Arg Phe Ala Thr Ala Phe Val Ile Ala Cys Val Leu Ser
  1               5                  10                  15

Leu Ile Ser Thr Ile Tyr Met Ala Ala Ser Ile Gly Thr Asp Phe Trp
             20                  25                  30

Tyr Glu Tyr Arg Ser Pro Val Gln Glu Asn Ser Ser Asp Leu Asn Lys
         35                  40                  45

Ser Ile Trp Xaa Glu Phe Ile Ser Asp Glu Ala Asp Xaa Lys Thr Tyr
     50                  55                  60

Asn Xaa Ala Leu Phe Arg Tyr Asn Gly Thr Val Gly Leu Trp Arg Arg
 65                  70                  75                  80

Cys Xaa Thr Ile Pro Lys Asn Xaa His Trp Tyr Ser Pro Pro Glu Arg
                 85                  90                  95

Xaa Gly Xaa Ser Leu Ile Leu Thr Ser Val Phe Phe Thr Trp Leu Ile
            100                 105                 110

Ile Asp Lys Thr Thr 
        115



<210> 2198
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2198
Met Gln Thr Phe Leu Gly Pro Phe Leu Cys Cys Gly Leu Ile Ser Leu
  1               5                  10                  15

Pro Pro Trp Ala Ala Val Asn Gly Ser Ile Cys Cys Leu Pro Ser Ser
             20                  25                  30

Gln Cys Ser Pro Asp Ala Ile Arg Asn Ser Asp Gly Gln Ser Trp Gly
         35                  40                  45

Lys Thr His Ser Thr Leu Leu Phe Leu Thr Cys Asn Lys Glu Ala Val
     50                  55                  60

Arg His Phe Val Ser Leu Trp Leu Trp Ile Cys Ala Phe Ala Leu Ile
 65                  70                  75                  80

Phe Lys Tyr Arg Phe Ser Phe Leu Leu Leu Gln Gln Asn Leu Ser Asn
                 85                  90                  95

Xaa Phe Trp Val Gly Xaa Xaa Lys Thr Val Cys Val Cys Val Cys Val
            100                 105                 110

Cys 




<210> 2199
<211> 121
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2199
Met Asp Ile Glu Glu Glu Gly Gln Val Trp Ser His Pro Glu Trp Phe
  1               5                  10                  15

Leu Leu Leu Pro Arg Cys Pro Gly Phe Ser His Gly Leu Xaa Trp Val
             20                  25                  30

Leu Pro Trp Val Leu Trp Met His Pro Ala Cys Trp Lys Phe Cys Ala
         35                  40                  45

Leu Cys Phe His Pro Phe Val Val Val Met Thr Val Tyr Leu Ser Pro
     50                  55                  60

Val Pro Ser Ser Ala Cys Ser Pro Cys Arg Pro Leu Ser Leu Trp Leu
 65                  70                  75                  80

Ser His Gln His Phe Pro Thr Ala Arg Cys Ser Ser Phe Leu Phe Ser
                 85                  90                  95

Gly Asp Leu Ser Thr Asp Cys Ile Val Pro Leu Ser Leu Ile Leu Lys
            100                 105                 110

Met Phe Leu Thr Thr Thr Lys Lys Lys 
        115                 120



<210> 2200
<211> 453
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2200
Met Glu His Trp Gly Gly Val Ser Ala Gly Ala Gly Phe Pro Gly Pro
  1               5                  10                  15

Gln Gln Ser Leu Pro Ala Gln Glu Gly His Phe Pro Trp Pro Arg Pro
             20                  25                  30

Gln Ala Asn Val His His Val Cys Glu Glu Leu Gln Val His Leu Ala
         35                  40                  45

Trp Cys Pro Pro Leu His Gln Phe His Ala Val Asp Leu Asp Gly Ala
     50                  55                  60

Ala Gly Pro Gly Ala Gly Cys Gly Leu Pro Ala Arg Leu Pro Leu His
 65                  70                  75                  80

Pro Pro Ala Arg His Thr Pro Ala Gln Arg His Asp His Pro Gln Glu
                 85                  90                  95

Gly Asn Ile Pro Val Cys Val Gln Leu Ala Val Cys Ala Leu Pro Leu
            100                 105                 110

Pro Val Val Pro Gly Pro Glu His Cys Gly Pro Gln Arg Xaa Leu Gln
        115                 120                 125

Pro Leu Val Tyr Pro Leu Ala Gln Val Ile Ile Gly Cys Ile Lys Leu
    130                 135                 140

Ile Pro Thr Ala Arg Phe Tyr Pro Leu Arg Met His Cys Ile Arg Ala
145                 150                 155                 160

Leu Thr Leu Leu Ser Gly Ser Ser Gly Ala Phe Ile Pro Val Leu Pro
                165                 170                 175

Phe Ile Leu Glu Met Phe Gln Gln Val Asp Phe Asn Arg Lys Pro Gly
            180                 185                 190

Arg Met Ser Ser Lys Pro Ile Asn Phe Ser Val Ile Leu Lys Leu Ser
        195                 200                 205

Asn Val Asn Leu Gln Glu Lys Ala Tyr Arg Asp Gly Leu Val Glu Gln
    210                 215                 220

Leu Tyr Asp Leu Thr Leu Glu Tyr Leu His Ser Gln Ala His Cys Ile
225                 230                 235                 240

Gly Phe Pro Glu Leu Val Leu Pro Val Val Leu Gln Leu Lys Ser Phe
                245                 250                 255

Leu Arg Glu Cys Lys Val Ala Asn Tyr Cys Arg Gln Val Gln Gln Leu
            260                 265                 270

Leu Gly Lys Val Gln Glu Asn Ser Ala Tyr Ile Cys Ser Arg Arg Gln
        275                 280                 285

Arg Val Ser Phe Gly Val Ser Glu Gln Gln Ala Val Glu Ala Trp Glu
    290                 295                 300

Lys Leu Thr Arg Glu Glu Gly Thr Pro Leu Thr Leu Tyr Tyr Ser His
305                 310                 315                 320

Trp Arg Lys Leu Arg Asp Arg Glu Ile Gln Leu Glu Ile Ser Gly Lys
                325                 330                 335

Glu Arg Leu Glu Asp Leu Asn Phe Pro Glu Ile Lys Arg Arg Lys Met
            340                 345                 350

Ala Asp Arg Lys Asp Glu Asp Arg Lys Gln Phe Lys Asp Leu Phe Asp
        355                 360                 365

Leu Asn Ser Ser Glu Glu Asp Asp Thr Glu Gly Phe Ser Glu Arg Gly
    370                 375                 380

Ile Leu Arg Pro Leu Ser Thr Arg His Gly Val Glu Asp Asp Glu Glu
385                 390                 395                 400

Asp Glu Glu Glu Gly Glu Glu Asp Ser Ser Asn Ser Glu Gly Glu Trp
                405                 410                 415

Ser Trp Asp Gly Asp Pro Asp Ala Glu Ala Gly Leu Ala Pro Gly Glu
            420                 425                 430

Leu Gln Gln Leu Ala Gln Gly Pro Glu Asp Glu Leu Glu Asp Leu Gln
        435                 440                 445

Leu Ser Glu Asp Asp 
    450



<210> 2201
<211> 106
<212> PRT
<213> Homo sapiens

<400> 2201
Met Arg Gly Trp Cys Pro Trp Pro Cys Gly Ala Ser Cys Gly Gly Ala
  1               5                  10                  15

Arg Val Ser Arg Ser Ala Trp Gly Pro Thr Pro Ser Trp Arg Leu Cys
             20                  25                  30

Ala Ser Thr Ala Thr Pro Ser Leu Ser Ser Ser Pro Trp Trp Ser Cys
         35                  40                  45

Gly Ser Ser Leu Cys Leu Gly Trp Gln Trp Leu Phe Gly Ala Leu Ala
     50                  55                  60

Leu Gly Leu Ser Ala Ala Gly Leu Val Phe Thr Leu Trp Pro Val Val
 65                  70                  75                  80

Arg Glu Asp Thr Arg Leu Val Ala Thr Val Leu Leu Ser Val Val Val
                 85                  90                  95

Leu Leu His Ala Leu Leu Ala Met Gly Leu 
            100                 105



<210> 2202
<211> 104
<212> PRT
<213> Homo sapiens

<400> 2202
Met Asp Arg Lys Asp Trp Ala Glu Lys Thr Ala Thr Ala Ser Arg His
  1               5                  10                  15

Arg Met Pro Gln Ser Trp Ala Pro Ser Leu Phe His Thr Thr Leu Gly
             20                  25                  30

Ser Phe Leu Gly Phe Arg Thr Phe Ser Ile Gly Phe Gln Asp Phe Glu
         35                  40                  45

Lys Cys Leu Pro Ile Leu Ile Ser Val Asp Pro Val Met Gly Ile Asn
     50                  55                  60

Leu Phe Gly Arg Gly Phe Leu Phe Leu Lys Met Lys Phe Pro Thr Phe
 65                  70                  75                  80

Phe Pro Gly Gly Asn Gln Tyr Gly Gln Arg Glu Glu Glu Met Ala Ile
                 85                  90                  95

Leu Thr Cys Val Ser His Val Thr 
            100



<210> 2203
<211> 284
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (31)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (274)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2203
Met Ala Ser Cys Leu Ala Thr Xaa Xaa Pro Pro Ser Ser Ala Phe Gly
  1               5                  10                  15

Leu Cys Pro Gln Ala Pro Ser Asp Xaa Gln Arg Asp Gly Gln Xaa Leu
             20                  25                  30

Asp Ser Leu Leu Pro Thr Trp Tyr Phe Leu Trp Arg Leu Leu Ala Leu
         35                  40                  45

Ala Ala Ala Arg Leu Pro Cys Gly Ala Val Pro Leu Ala Ala Ala Gly
     50                  55                  60

Leu Pro Ala Ala Arg Leu Pro Leu Pro Leu Arg Val Val Leu Arg Ala
 65                  70                  75                  80

His Leu Gln Leu His Val Ala Pro His Ala Pro His Leu Leu Leu Pro
                 85                  90                  95

Arg Leu Arg Arg Ala Gln Pro Leu Gln Ser Gly Phe Leu Glu Leu Glu
            100                 105                 110

Ser Pro Gly Leu Ser Lys Val Leu Arg Thr Gly Ala Phe Ala Tyr Pro
        115                 120                 125

Phe Leu Phe Asp Asn Leu Pro Leu Phe Tyr Arg Leu Gly Leu Cys Trp
    130                 135                 140

Gly Arg Gly His Gly Cys Gly Gln Glu Ala Leu Ser Thr Ser His Gly
145                 150                 155                 160

Tyr His Leu Phe Cys Ala Leu Leu Thr Gly Phe Leu Phe Ala Ser His
                165                 170                 175

Leu Pro Glu Ser Trp His Gln Asp Ala Leu Ile Thr Ser Ala Thr Ala
            180                 185                 190

Thr Ser Tyr Ser Thr Ser Val Gln Cys Trp Ala Pro Thr Ser Ser Trp
        195                 200                 205

Arg Gln Cys Trp Leu Ile Trp Asp His Ala Glu Pro Gly Trp Pro His
    210                 215                 220

Arg Asn Leu Pro Trp Ala Trp Gln Ala Gln Trp Pro His Trp Ser Trp
225                 230                 235                 240

Leu Gln Leu Gly Thr Thr His Tyr Cys Cys Phe His Ser Gln Pro Ala
                245                 250                 255

Ser Gly Pro Gln Tyr Met Pro Ser Ala Ala Arg Trp Pro Thr Gly Gly
            260                 265                 270

Gly Xaa Pro Gly Gln Thr Thr Val Arg Pro His Pro 
        275                 280



<210> 2204
<211> 124
<212> PRT
<213> Homo sapiens

<400> 2204
Met Ala Asp Asp Leu Lys Arg Phe Leu Tyr Lys Lys Leu Pro Ser Val
  1               5                  10                  15

Glu Gly Leu His Ala Ile Val Val Ser Asp Arg Asp Gly Val Pro Val
             20                  25                  30

Ile Lys Val Ala Asn Asp Asn Ala Pro Glu His Ala Leu Arg Pro Gly
         35                  40                  45

Phe Leu Ser Thr Phe Ala Leu Ala Thr Asp Gln Gly Ser Lys Leu Gly
     50                  55                  60

Leu Ser Lys Asn Lys Ser Ile Ile Cys Tyr Tyr Asn Thr Tyr Gln Val
 65                  70                  75                  80

Val Gln Phe Asn Arg Leu Pro Leu Val Val Ser Phe Ile Ala Ser Ser
                 85                  90                  95

Ser Ala Asn Thr Gly Leu Ile Val Ser Leu Glu Lys Glu Leu Ala Pro
            100                 105                 110

Leu Phe Glu Glu Leu Arg Gln Val Val Glu Val Ser 
        115                 120



<210> 2205
<211> 238
<212> PRT
<213> Homo sapiens

<400> 2205
Met Pro Phe Ala Thr Val Ile Phe Phe Val Met Ile Leu Asp Phe Tyr
  1               5                  10                  15

Val Asp Ser Ile Cys Ser Val Lys Met Glu Val Ser Lys Cys Ala Arg
             20                  25                  30

Tyr Gly Ser Phe Pro Ile Phe Ile Ser Ala Leu Leu Phe Gly Asn Phe
         35                  40                  45

Trp Thr His Pro Ile Thr Asp Gln Leu Arg Ala Met Asn Lys Ala Ala
     50                  55                  60

His Gln Glu Ser Thr Glu His Val Leu Ser Gly Gly Val Val Val Ser
 65                  70                  75                  80

Ala Ile Phe Phe Ile Leu Ser Ala Asn Ile Leu Ser Ser Pro Ser Lys
                 85                  90                  95

Arg Gly Gln Lys Gly Thr Leu Ile Gly Tyr Ser Pro Glu Gly Thr Pro
            100                 105                 110

Leu Tyr Asn Phe Met Gly Asp Ala Phe Gln His Ser Ser Gln Ser Ile
        115                 120                 125

Pro Arg Phe Ile Lys Glu Ser Leu Lys Gln Ile Leu Glu Glu Ser Asp
    130                 135                 140

Ser Arg Gln Ile Phe Tyr Phe Leu Cys Leu Asn Leu Leu Phe Thr Phe
145                 150                 155                 160

Val Glu Leu Phe Tyr Gly Val Leu Thr Asn Ser Leu Gly Leu Ile Ser
                165                 170                 175

Asp Gly Phe His Met Leu Phe Asp Cys Ser Ala Leu Val Met Gly Leu
            180                 185                 190

Phe Ala Ala Leu Met Ser Arg Trp Lys Ala Thr Arg Ile Phe Ser Tyr
        195                 200                 205

Gly Tyr Gly Arg Ile Glu Ile Leu Ser Gly Phe Ile Asn Gly Leu Phe
    210                 215                 220

Leu Ile Val Ile Ala Phe Phe Val Phe Met Gly Val Ser Gly 
225                 230                 235



<210> 2206
<211> 152
<212> PRT
<213> Homo sapiens

<400> 2206
Met Glu Ala Val Leu Asn Glu Leu Val Ser Val Glu Asp Leu Leu Lys
  1               5                  10                  15

Phe Glu Lys Lys Phe Gln Ser Glu Lys Ala Ala Gly Ser Val Ser Lys
             20                  25                  30

Ser Thr Gln Phe Glu Tyr Ala Trp Cys Leu Val Arg Ser Lys Tyr Asn
         35                  40                  45

Asp Asp Ile Arg Lys Gly Ile Val Leu Leu Glu Glu Leu Leu Pro Lys
     50                  55                  60

Gly Ser Lys Glu Glu Gln Arg Asp Tyr Val Phe Tyr Leu Ala Val Gly
 65                  70                  75                  80

Asn Tyr Arg Leu Lys Glu Tyr Glu Lys Ala Leu Lys Tyr Val Arg Gly
                 85                  90                  95

Leu Leu Gln Thr Glu Pro Gln Asn Asn Gln Ala Lys Glu Leu Glu Arg
            100                 105                 110

Leu Ile Asp Lys Ala Met Lys Lys Asp Gly Leu Val Gly Met Ala Ile
        115                 120                 125

Val Gly Gly Met Ala Leu Gly Val Ala Gly Leu Ala Gly Leu Ile Gly
    130                 135                 140

Leu Ala Val Ser Lys Ser Lys Ser 
145                 150



<210> 2207
<211> 115
<212> PRT
<213> Homo sapiens

<400> 2207
Met Trp Leu Tyr Arg Asn Pro Tyr Val Glu Ala Glu Tyr Phe Pro Thr
  1               5                  10                  15

Lys Pro Met Phe Val Ile Ala Phe Leu Ser Pro Leu Ser Leu Ile Phe
             20                  25                  30

Leu Ala Lys Phe Leu Lys Lys Ala Asp Thr Arg Asp Ser Arg Gln Ala
         35                  40                  45

Cys Leu Ala Ala Ser Leu Ala Leu Ala Leu Asn Gly Val Phe Thr Asn
     50                  55                  60

Thr Ile Lys Leu Ile Val Gly Ser Ile Ser His Gln Arg Pro Gln Gln
 65                  70                  75                  80

Ser Val Ser Val Leu Leu Ser Thr Phe Leu Lys Leu Gln Cys His Leu
                 85                  90                  95

Leu Phe Ala Leu Lys Ser His Ala Gln Ile Ser Ser Thr Ala Ala Ser
            100                 105                 110

Leu Met Gly 
        115



<210> 2208
<211> 322
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2208
Met Asn Phe Ser Ile Phe Leu Gln Glu Met Ser Leu Phe Lys Gln Gln
  1               5                  10                  15

Ser Pro Gly Lys Phe Cys Leu Leu Val Cys Ser Val Cys Thr Phe Phe
             20                  25                  30

Thr Ile Leu Gly Ser Tyr Ile Pro Gly Val Ile Leu Ser Tyr Leu Leu
         35                  40                  45

Leu Leu Cys Ala Phe Leu Cys Pro Leu Phe Lys Cys Asn Asp Ile Gly
     50                  55                  60

Gln Lys Ile Tyr Ser Lys Ile Lys Ser Val Leu Leu Lys Leu Asp Phe
 65                  70                  75                  80

Gly Ile Gly Glu Tyr Ile Asn Gln Lys Lys Arg Glu Arg Ser Glu Ala
                 85                  90                  95

Asp Lys Glu Lys Ser His Lys Asp Asp Ser Glu Leu Asp Phe Ser Xaa
            100                 105                 110

Leu Cys Pro Lys Ile Ser Leu Thr Val Ala Ala Lys Glu Leu Ser Val
        115                 120                 125

Ser Asp Thr Asp Val Ser Glu Val Ser Trp Thr Asp Asn Gly Thr Phe
    130                 135                 140

Asn Leu Ser Glu Gly Tyr Thr Pro Gln Thr Asp Thr Ser Asp Asp Leu
145                 150                 155                 160

Asp Arg Pro Ser Glu Glu Val Phe Ser Arg Asp Leu Ser Asp Phe Pro
                165                 170                 175

Ser Leu Glu Asn Gly Met Gly Thr Asn Asp Glu Asp Glu Leu Ser Leu
            180                 185                 190

Gly Leu Pro Thr Glu Leu Lys Arg Lys Lys Glu Gln Leu Asp Ser Gly
        195                 200                 205

His Arg Pro Ser Lys Glu Thr Gln Ser Ala Ala Gly Leu Thr Leu Pro
    210                 215                 220

Leu Asn Ser Asp Gln Thr Phe His Leu Met Ser Asn Leu Ala Gly Asp
225                 230                 235                 240

Val Ile Thr Ala Ala Val Thr Ala Ala Ile Lys Asp Gln Leu Glu Gly
                245                 250                 255

Val Gln Gln Ala Leu Ser Gln Ala Ala Pro Ile Pro Glu Glu Asp Thr
            260                 265                 270

Asp Thr Glu Glu Gly Asp Asp Phe Glu Leu Leu Asp Gln Ser Glu Leu
        275                 280                 285

Asp Gln Ile Glu Ser Glu Leu Gly Leu Thr Gln Asp Gln Glu Ala Glu
    290                 295                 300

Ala Gln Gln Asn Lys Lys Ser Ser Gly Phe Leu Ser Asn Leu Leu Gly
305                 310                 315                 320

Gly His 




<210> 2209
<211> 167
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (155)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2209
Met Ile Leu Gly Arg Val Ile Met Gln Ile Ile Lys Asp Met Val Leu
  1               5                  10                  15

Ser Arg Thr Arg Gly Ala Gln Leu Trp Arg Ser Leu Ser Glu Ser Trp
             20                  25                  30

Glu Val Ile Asn Ser Lys Pro Asp Glu Arg Pro Arg Leu Ser His Cys
         35                  40                  45

Ile Ala Glu Ser Trp Met Asn Phe Ser Ile Phe Leu Gln Glu Met Ser
     50                  55                  60

Leu Phe Lys Gln Gln Ser Pro Gly Lys Phe Cys Leu Leu Val Cys Ser
 65                  70                  75                  80

Val Cys Thr Phe Phe Thr Ile Leu Gly Ser Tyr Ile Pro Gly Val Ile
                 85                  90                  95

Leu Ser Tyr Leu Leu Leu Leu Cys Ala Phe Leu Cys Pro Leu Phe Lys
            100                 105                 110

Cys Asn Asp Ile Gly Gln Lys Ile Tyr Ser Lys Ile Lys Ser Val Leu
        115                 120                 125

Leu Lys Leu Asp Phe Gly Ile Gly Glu Tyr Ile Asn Gln Lys Lys Arg
    130                 135                 140

Glu Arg Ser Glu Ala Asp Lys Glu Lys Ser Xaa Lys Asp Asp Ser Glu
145                 150                 155                 160

Leu Thr Phe His Ser Leu Ser 
                165



<210> 2210
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2210
Met Leu Ala Cys His His Gly Asn Val Asp Leu Val Arg Leu Leu Leu
  1               5                  10                  15

Ala His Pro Ala Cys Xaa Ser Ser Leu Thr Asp Lys Ala Gly Arg Thr
             20                  25                  30

Ala Leu Ser Ile Ala Leu Lys Ser Pro Thr His Met Glu Ile Ala Gly
         35                  40                  45

Leu Leu Arg Ala His Ala Asp Arg Ala Gly Pro Trp Gly Cys Arg Gly
     50                  55                  60

Cys Arg Arg Thr Gly Arg Gly Glu Gln Lys Pro Ser Ser Leu Asp Ser
 65                  70                  75                  80

Ser Leu Ala Leu Glu Glu Gly Arg Gly His Arg Pro Glu Ser His Pro
                 85                  90                  95

Ser Arg Glu Glu Thr Met Ser Asn Met His Ile His Ser Cys Cys Ile
            100                 105                 110

Ile Leu Leu Ile Arg Met Leu Cys Ser Phe Cys Leu Arg Pro Ser Leu
        115                 120                 125

Lys Thr Thr Arg Ala Ser Glu Gln Gly Ser Ser Ala Ser Glu Gly Tyr
    130                 135                 140

Val Val Ser Ser Lys His Pro Lys His Leu Gln Pro 
145                 150                 155



<210> 2211
<211> 483
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (461)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (465)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (467)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2211
Met Ala Gly Lys Gly Ser Ser Gly Arg Arg Pro Leu Leu Leu Gly Leu
  1               5                  10                  15

Leu Val Ala Val Ala Thr Val His Leu Val Ile Cys Pro Tyr Thr Lys
             20                  25                  30

Val Glu Glu Ser Phe Asn Leu Gln Ala Thr His Asp Leu Leu Tyr His
         35                  40                  45

Trp Gln Asp Leu Glu Gln Tyr Asp His Leu Glu Phe Pro Gly Val Val
     50                  55                  60

Pro Arg Thr Phe Leu Gly Pro Val Val Ile Ala Val Phe Ser Ser Pro
 65                  70                  75                  80

Ala Val Tyr Val Leu Ser Leu Leu Glu Met Ser Lys Phe Tyr Ser Gln
                 85                  90                  95

Leu Ile Val Arg Gly Val Leu Gly Leu Gly Val Ile Phe Gly Leu Trp
            100                 105                 110

Thr Leu Gln Lys Glu Val Arg Arg His Phe Gly Ala Met Val Ala Thr
        115                 120                 125

Met Phe Cys Trp Val Thr Ala Met Gln Phe His Leu Met Phe Tyr Cys
    130                 135                 140

Thr Arg Thr Leu Pro Asn Val Leu Ala Leu Pro Val Val Leu Leu Ala
145                 150                 155                 160

Leu Ala Ala Trp Leu Arg His Glu Trp Ala Arg Phe Ile Trp Leu Ser
                165                 170                 175

Ala Phe Ala Ile Ile Val Phe Arg Val Glu Leu Cys Leu Phe Leu Gly
            180                 185                 190

Leu Leu Leu Leu Leu Ala Leu Gly Asn Arg Lys Val Ser Val Val Arg
        195                 200                 205

Ala Leu Arg His Ala Val Pro Ala Gly Ile Leu Cys Leu Gly Leu Thr
    210                 215                 220

Val Ala Val Asp Ser Tyr Phe Trp Arg Gln Leu Thr Trp Pro Glu Gly
225                 230                 235                 240

Lys Val Leu Trp Tyr Asn Thr Val Leu Asn Lys Ser Ser Asn Trp Gly
                245                 250                 255

Thr Ser Pro Leu Leu Trp Tyr Phe Tyr Ser Ala Leu Pro Arg Gly Leu
            260                 265                 270

Gly Cys Ser Leu Leu Phe Ile Pro Leu Gly Leu Val Asp Arg Arg Thr
        275                 280                 285

His Ala Pro Thr Val Leu Ala Leu Gly Phe Met Ala Leu Tyr Ser Leu
    290                 295                 300

Leu Pro His Lys Glu Leu Arg Phe Ile Ile Tyr Ala Phe Pro Met Leu
305                 310                 315                 320

Asn Ile Thr Ala Ala Arg Gly Cys Ser Tyr Leu Leu Asn Asn Tyr Lys
                325                 330                 335

Lys Ser Trp Leu Tyr Lys Ala Gly Ser Leu Leu Val Ile Gly His Leu
            340                 345                 350

Val Val Asn Ala Ala Tyr Ser Ala Thr Ala Leu Tyr Val Ser His Phe
        355                 360                 365

Asn Tyr Pro Gly Gly Val Ala Met Gln Arg Leu His Gln Leu Val Pro
    370                 375                 380

Pro Gln Thr Asp Val Leu Leu His Ile Asp Val Ala Ala Ala Gln Thr
385                 390                 395                 400

Gly Val Ser Arg Phe Leu Gln Val Asn Ser Ala Trp Arg Tyr Asp Lys
                405                 410                 415

Arg Glu Asp Val Gln Pro Gly Thr Gly Met Leu Ala Tyr Thr His Ile
            420                 425                 430

Leu Met Glu Ala Ala Pro Gly Leu Leu Ala Leu Tyr Arg Asp Thr His
        435                 440                 445

Arg Val Leu Ala Ser Val Val Gly Thr Thr Gly Val Xaa Leu Asn Leu
    450                 455                 460

Xaa Gln Xaa Ala Pro Phe Asn Val His Leu Gln Thr Lys Leu Val Leu
465                 470                 475                 480

Leu Gly Lys 




<210> 2212
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2212
Met Ser Ser Leu Leu Pro Thr Met Trp Leu Gly Ala Gln Asn Gly Cys
  1               5                  10                  15

Leu Tyr Val His Ser Ser Val Ala Gln Trp Arg Lys Cys Leu His Ser
             20                  25                  30

Ile Lys Leu Lys Asp Ser Ile Leu Ser Ile Val His Val Lys Gly Ile
         35                  40                  45

Val Leu Val Ala Leu Ala Asp Gly Thr Leu Ala Ile Phe His Arg Gly
     50                  55                  60

Val Asp Gly Gln Trp Asp Leu Ser Asn Tyr His Leu Leu Asp Leu Gly
 65                  70                  75                  80

Arg Pro His His Ser Ile Arg Cys Met Thr Val Val His Asp Lys Val
                 85                  90                  95

Trp Cys Gly Tyr Arg Xaa Lys Ile Tyr Val Val Gln Pro Lys Ala Xaa
            100                 105                 110

Glu Asn Arg Glu Ile Phe 
        115



<210> 2213
<211> 132
<212> PRT
<213> Homo sapiens

<400> 2213
Met His Pro Trp Asn Gln Gln Val Pro Asp Lys Glu Ser Gly Gly Gly
  1               5                  10                  15

Ser His Gly Asn Ala Ala Ser Ser Cys Ser Arg Phe His Tyr Ser Tyr
             20                  25                  30

Ala Gly Val His Ser Glu Ser Thr His Phe Ser Leu Val Leu Leu Leu
         35                  40                  45

Asp Trp Ala Met Ala Phe Ile Leu Cys Pro Leu Thr Cys Pro Gly Glu
     50                  55                  60

Cys Glu Gly Ser Thr Gly Lys Leu Glu Cys Cys Leu Cys Leu Pro Ser
 65                  70                  75                  80

Gln Trp Ala Val Leu Thr Ala Ala Pro His Pro Tyr Arg Trp Ser Gln
                 85                  90                  95

Glu Ala Gly Arg Val Gly Glu Gly Lys Ile Gly Lys Thr Gly Arg Pro
            100                 105                 110

Arg Pro Arg Gln Asn Ser Leu Ser Ser Leu His Phe Trp Ser Pro Val
        115                 120                 125

Val Met Cys Leu 
    130



<210> 2214
<211> 345
<212> PRT
<213> Homo sapiens

<400> 2214
Met Leu Ala Ala Arg Leu Val Cys Leu Arg Thr Leu Pro Ser Arg Val
  1               5                  10                  15

Phe His Pro Ala Phe Thr Lys Ala Ser Pro Val Val Lys Asn Ser Ile
             20                  25                  30

Thr Lys Asn Gln Trp Leu Leu Thr Pro Ser Arg Glu Tyr Ala Thr Lys
         35                  40                  45

Thr Arg Ile Gly Ile Arg Arg Gly Arg Thr Gly Gln Glu Leu Lys Glu
     50                  55                  60

Ala Ala Leu Glu Pro Ser Met Glu Lys Ile Phe Lys Ile Asp Gln Met
 65                  70                  75                  80

Gly Arg Trp Phe Val Ala Gly Gly Ala Ala Val Gly Leu Gly Ala Leu
                 85                  90                  95

Cys Tyr Tyr Gly Leu Gly Leu Ser Asn Glu Ile Gly Ala Ile Glu Lys
            100                 105                 110

Ala Val Ile Trp Pro Gln Tyr Val Lys Asp Arg Ile His Ser Thr Tyr
        115                 120                 125

Met Tyr Leu Ala Gly Ser Ile Gly Leu Thr Ala Leu Ser Ala Ile Ala
    130                 135                 140

Ile Ser Arg Thr Pro Val Leu Met Asn Phe Met Met Arg Gly Ser Trp
145                 150                 155                 160

Val Thr Ile Gly Val Thr Phe Ala Ala Met Val Gly Ala Gly Met Leu
                165                 170                 175

Val Arg Ser Ile Pro Tyr Asp Gln Ser Pro Gly Pro Lys His Leu Ala
            180                 185                 190

Trp Leu Leu His Ser Gly Val Met Gly Ala Val Val Ala Pro Leu Thr
        195                 200                 205

Ile Leu Gly Gly Pro Leu Leu Ile Arg Ala Ala Trp Tyr Thr Ala Gly
    210                 215                 220

Ile Val Gly Gly Leu Ser Thr Val Ala Met Cys Ala Pro Ser Glu Lys
225                 230                 235                 240

Phe Leu Asn Met Gly Ala Pro Leu Gly Val Gly Leu Gly Leu Val Phe
                245                 250                 255

Val Ser Ser Leu Gly Ser Met Phe Leu Pro Pro Thr Thr Val Ala Gly
            260                 265                 270

Ala Thr Leu Tyr Ser Val Ala Met Tyr Gly Gly Leu Val Leu Phe Ser
        275                 280                 285

Met Phe Leu Leu Tyr Asp Thr Gln Lys Val Ile Lys Arg Ala Glu Val
    290                 295                 300

Ser Pro Met Tyr Gly Val Gln Lys Tyr Asp Pro Ile Asn Ser Met Leu
305                 310                 315                 320

Ser Ile Tyr Met Asp Thr Leu Asn Ile Phe Met Arg Val Ala Thr Met
                325                 330                 335

Leu Ala Thr Gly Gly Asn Arg Lys Lys 
            340                 345



<210> 2215
<211> 142
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2215
Met Leu Val Glu Lys Ser Leu Ser Val Ile Leu Leu Val Val Ala Leu
  1               5                  10                  15

Ala Met Leu Ile Ile Asp Leu Arg Met Lys Ser Phe Leu Ala Ile Pro
             20                  25                  30

Asn Leu Val Ile Phe Ala Val Leu Leu Phe Phe Ser Ser Leu Glu Thr
         35                  40                  45

Pro Lys Asn Pro Ile Ala Phe Ala Cys Phe Phe Ile Cys Leu Ile Thr
     50                  55                  60

Asp Pro Phe Leu Asp Ile Tyr Phe Ser Gly Leu Ser Val Thr Glu Arg
 65                  70                  75                  80

Trp Lys Pro Phe Leu Tyr Arg Gly Arg Ile Cys Arg Arg Leu Xaa Val
                 85                  90                  95

Val Phe Ala Gly Met Ile Glu Leu Thr Phe Phe Ile Leu Ser Ala Phe
            100                 105                 110

Lys Leu Arg Asp Thr His Leu Trp Tyr Phe Val Ile Pro Gly Phe Ser
        115                 120                 125

Ile Phe Gly Ile Phe Trp Met Ile Cys His Ile Ile Phe Phe 
    130                 135                 140



<210> 2216
<211> 227
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2216
Met Lys Lys Ile Leu Glu Val Val Asn Gln Ile Gln Asp Glu Glu Arg
  1               5                  10                  15

Met Val Gln Ser Gln Lys Ser Ser Ser Pro Leu Ser Ser Thr Arg Ser
             20                  25                  30

Lys Arg Ser Thr Leu Leu Pro Pro Glu Ala Ser Glu Gly Ser Ser Ser
         35                  40                  45

Phe Leu Gly Lys Leu Met Gly Phe Ile Ala Thr Pro Phe Ile Lys Leu
     50                  55                  60

Phe Gln Leu Ile Tyr Tyr Leu Met Val Ala Ile Leu Lys Asn Ile Val
 65                  70                  75                  80

Tyr Phe Leu Trp Cys Val Thr Lys Gln Val Ile Asn Gly Ile Glu Ser
                 85                  90                  95

Cys Leu Tyr Arg Leu Gly Ser Ala Thr Ile Ser Tyr Phe Met Ala Ile
            100                 105                 110

Gly Glu Glu Leu Val Ser Ile Pro Trp Lys Xaa Leu Lys Val Val Ala
        115                 120                 125

Xaa Val Ile Arg Ala Leu Leu Arg Ile Leu Cys Cys Leu Leu Lys Ala
    130                 135                 140

Ile Cys Arg Val Leu Ser Ile Pro Val Arg Val Leu Val Asp Val Ala
145                 150                 155                 160

Thr Phe Pro Val Tyr Thr Met Xaa Ala Ile Pro Ile Val Cys Lys Asp
                165                 170                 175

Ile Ala Leu Gly Leu Gly Gly Thr Val Ser Leu Leu Phe Asp Thr Ala
            180                 185                 190

Phe Gly Thr Leu Gly Gly Leu Phe Gln Val Val Phe Ser Val Cys Lys
        195                 200                 205

Arg Ile Gly Tyr Lys Val Thr Phe Asp Asn Ser Gly Gly Val Ile Asn
    210                 215                 220

Ser Lys Asn 
225



<210> 2217
<211> 100
<212> PRT
<213> Homo sapiens

<400> 2217
Met Glu Ala Val Ser Gln Ile Ala Gly Phe Val Thr Ile Leu Gly Pro
  1               5                  10                  15

Ser Gln Asp His Tyr Met Leu Leu Val Ala Pro Glu Ile Asp Phe Ser
             20                  25                  30

Asp Thr Pro Asn Val Thr Ile Tyr Leu His Gln Phe Pro Pro Asn Val
         35                  40                  45

Thr Phe Gln Ile Gln Ile Gln Leu Leu Lys Pro Gly His Ile Phe Ile
     50                  55                  60

Leu Cys Leu Val Ile Ser Pro Lys Ser His Pro Ser Pro Pro Pro Pro
 65                  70                  75                  80

Gly Leu Ser Ile Ser Lys Pro Ile Arg Asp Lys Phe Ser Asn Leu Ser
                 85                  90                  95

Arg Thr Gln Thr 
            100



<210> 2218
<211> 188
<212> PRT
<213> Homo sapiens

<400> 2218
Met Ile Arg Tyr Phe Thr Ser Asn Pro Ala Ser Lys Val Leu Cys Ser
  1               5                  10                  15

Pro Met Leu Leu Ser Thr Phe Ser His Phe Ser Leu Phe His Met Ala
             20                  25                  30

Ala Asn Met Tyr Val Leu Trp Ser Phe Ser Ser Ser Ile Val Asn Ile
         35                  40                  45

Leu Gly Gln Glu Gln Phe Met Ala Val Tyr Leu Ser Ala Gly Val Ile
     50                  55                  60

Ser Asn Phe Val Ser Tyr Val Gly Lys Val Ala Thr Gly Arg Tyr Gly
 65                  70                  75                  80

Pro Ser Leu Gly Ala Ser Gly Ala Ile Met Thr Val Leu Ala Ala Val
                 85                  90                  95

Cys Thr Lys Ile Pro Glu Gly Arg Leu Ala Ile Ile Phe Leu Pro Met
            100                 105                 110

Phe Thr Phe Thr Ala Gly Asn Ala Leu Lys Ala Ile Ile Ala Met Asp
        115                 120                 125

Thr Ala Gly Met Ile Leu Gly Trp Lys Phe Phe Asp His Ala Ala His
    130                 135                 140

Leu Gly Gly Ala Leu Phe Gly Ile Trp Tyr Val Thr Tyr Gly His Glu
145                 150                 155                 160

Leu Ile Trp Lys Asn Arg Glu Pro Leu Val Lys Ile Trp His Glu Ile
                165                 170                 175

Arg Thr Asn Gly Pro Lys Lys Gly Gly Gly Ser Lys 
            180                 185



<210> 2219
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2219
Met Arg Arg Arg Phe Trp Gly Val Phe Asn Cys Leu Cys Ala Gly Ala
  1               5                  10                  15

Phe Gly Ala Leu Ala Ala Ala Ser Ala Lys Leu Ala Phe Gly Ser Glu
             20                  25                  30

Val Ser Met Gly Leu Cys Val Leu Gly Ile Ile Val Met Ala Ser Thr
         35                  40                  45

Asn Ser Leu Met Trp Thr Phe Phe Ser Arg Gly Leu Ser Phe Ser Met
     50                  55                  60

Ser Ser Ala Ile Ala Ser Val Thr Val Thr Phe Ser Asn Ile Leu Ser
 65                  70                  75                  80

Ser Ala Phe Leu Gly Leu Cys Ala Val Trp Arg Val Pro Gly Val Leu
                 85                  90                  95

Trp Trp Gly Xaa Val Phe Leu Xaa Leu Cys Gly Thr Ser Pro Asn Pro
            100                 105                 110

Gln Glu Ala Pro Thr His Leu Glu Ala Pro Ser Thr Gln Ala Ala Val
        115                 120                 125

Ala Thr Thr Trp Leu Arg Arg Thr Ser Trp Lys Asp His Asp Gly Trp
    130                 135                 140

Ala Gln Leu Trp Asp Val Lys Trp Glu Leu Cys Ser 
145                 150                 155



<210> 2220
<211> 129
<212> PRT
<213> Homo sapiens

<400> 2220
Met Leu Phe Tyr Leu Ser Ser Gln Pro Asp Trp Gln Leu Asp Phe Phe
  1               5                  10                  15

Arg Val Ser Phe Asn Gly Pro Val Phe Phe Ile Ile Ile Phe Asn Asp
             20                  25                  30

Arg Ala Gly Phe Arg Met Gln Ala Leu Val Ser Gln Ala Ala Cys Arg
         35                  40                  45

Arg Ser Arg Tyr Lys Leu Ser Val Val Tyr Met Val Gln Gly Pro Leu
     50                  55                  60

Thr His Leu Met Leu Val Leu Leu Ile Ser Leu Ile Phe Leu Ser Arg
 65                  70                  75                  80

Gly Ser Gly Arg Ala Trp Ala Phe Ser His Ser Cys Phe Lys Thr Ser
                 85                  90                  95

Asp Leu Leu Pro Cys Arg Asn Arg Trp Glu Val Ile Glu Phe Leu His
            100                 105                 110

Tyr Ser Asn Leu His Ser His Ile Ser Leu Ser Val Thr Lys Thr Phe
        115                 120                 125

Leu 




<210> 2221
<211> 120
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2221
Met Gly Leu Leu Ala Leu Pro Phe Phe Ala Ile Leu Val Met Asp Arg
  1               5                  10                  15

Gly Trp Pro Arg Gly Thr Trp Leu Pro Val Thr Ser Gly Arg Leu His
             20                  25                  30

Ala Gly Gln Gly Arg Val Thr Leu Pro Leu Ala Gly Gly Gly Met Arg
         35                  40                  45

Leu Pro Arg Gly Thr Gln Val Ser Leu Xaa Leu Ala Leu Tyr Pro Val
     50                  55                  60

Ser Phe Ala Val Phe Met Cys Ser Asp Ala Leu Pro Leu Gly Ala Ser
 65                  70                  75                  80

Lys Leu Gln Cys Pro Leu Pro Pro Gly Arg Gly Asp Pro Gln Ala Pro
                 85                  90                  95

Ser Ala Gln Arg Cys Thr Cys Leu Val Ala Leu Leu Leu Pro Gly Thr
            100                 105                 110

Val Asp Leu Ser Val Cys Leu Phe 
        115                 120



<210> 2222
<211> 130
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2222
Met Lys Lys Thr Glu Pro Ser Trp Pro Pro Val Ser Pro Leu Cys Leu
  1               5                  10                  15

Ser Leu Met Gly Cys Leu Gly Ala Ala Cys Thr Ala Gln Xaa Ala Phe
             20                  25                  30

Thr Val Arg Ser Gly Ser Val Gly Ser Val Val Pro Val Leu Pro Ala
         35                  40                  45

Val Pro Ser Gly Glu Ala Leu Val Ala Leu Arg Trp Thr Lys Ser Ser
     50                  55                  60

Arg Lys Lys Arg Gln Arg Asp Ala Ser His Ser Pro Pro Gln Thr Leu
 65                  70                  75                  80

Gly Gln Ala Pro Leu Gly Pro Ala Ala Cys Leu Arg Arg Trp Ala Gln
                 85                  90                  95

Gly Gly Trp Gln Gly Val Pro Ala Ala Cys Phe Arg Thr Ser Gln Phe
            100                 105                 110

Phe Leu Pro Ser Leu Pro Cys Leu Gln Asn His Ser Pro Ser Pro Gln
        115                 120                 125

Gly Gly 
    130



<210> 2223
<211> 256
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (218)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (224)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (233)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (246)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (256)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2223
Met Leu Lys Trp Met Tyr Ile Pro Ala Ser Asn Asn Asn Thr Pro Ile
  1               5                  10                  15

His Gly Phe Tyr Ile Tyr Tyr Arg Pro Thr Asp Ser Asp Asn Asp Ser
             20                  25                  30

Asp Tyr Lys Lys Asp Met Val Glu Gly Asp Lys Tyr Trp His Ser Ile
         35                  40                  45

Ser His Leu Gln Pro Glu Thr Ser Tyr Asp Ile Lys Met Gln Cys Phe
     50                  55                  60

Asn Glu Gly Gly Glu Ser Glu Phe Ser Asn Val Met Ile Cys Glu Thr
 65                  70                  75                  80

Lys Ala Arg Lys Ser Ser Gly Gln Pro Gly Arg Leu Pro Pro Pro Thr
                 85                  90                  95

Leu Ala Pro Pro Gln Pro Pro Leu Pro Glu Thr Ile Glu Arg Pro Val
            100                 105                 110

Gly Thr Gly Ala Met Val Ala Arg Ser Xaa Asp Leu Pro Tyr Leu Ile
        115                 120                 125

Val Gly Val Val Leu Gly Ser Ile Val Leu Ile Ile Val Thr Phe Ile
    130                 135                 140

Pro Phe Cys Leu Trp Arg Ala Trp Ser Lys Gln Lys His Thr Thr Asp
145                 150                 155                 160

Leu Gly Phe Pro Arg Ser Ala Leu Pro Pro Ser Cys Pro Tyr Thr Met
                165                 170                 175

Val Pro Leu Gly Gly Leu Pro Gly His Gln Ala Ser Gly Gln Pro Tyr
            180                 185                 190

Leu Ser Gly Ile Ser Gly Arg Ala Cys Ala Asn Gly Ile His Met Asn
        195                 200                 205

Arg Gly Cys Pro Ser Ala Ala Val Gly Xaa Pro Gly Met Lys Pro Xaa
    210                 215                 220

Gln His Cys Pro Gly Glu Leu Gln Xaa Val Ala Xaa Ser Trp Val Trp
225                 230                 235                 240

Ala Ala Val Trp Asp Xaa Gln Lys Asp Cys Trp Ala Ala Trp Gly Xaa
                245                 250                 255






<210> 2224
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2224
Met Leu Phe Val Val Met Met Ser Pro Asp Ile Val Met Ala Ile Ser
  1               5                  10                  15

Leu Leu Val Leu Phe Met Leu Leu Gly Ile Gln Leu Gly Phe Trp Ser
             20                  25                  30

Leu Leu Phe Ser His Ile Thr Phe Cys Leu Pro Phe Val Val Val Thr
         35                  40                  45

Val Tyr Ser Arg Leu Lys Gly Phe Asp Val Arg Met Leu Glu Ala Ala
     50                  55                  60

Lys Asp Leu Gly Ala Ser Glu Phe Thr Ile Leu Arg Lys Ile Ile Leu
 65                  70                  75                  80

Pro Leu Ala Met Pro Ala Val Ala Xaa Gly Trp Val Leu Ser Phe Thr
                 85                  90                  95

Leu Ser Met Asp Asp Val Val Val Ser Ser Phe Val Thr Gly Pro Ser
            100                 105                 110

Tyr Glu Ile Leu Pro Leu Lys Ile Tyr Ser Met Val Lys Val Gly Val
        115                 120                 125

Ser Gly Xaa Leu Thr Arg Trp Gln Pro Tyr Tyr Trp Cys Cys Arg Trp
    130                 135                 140






<210> 2225
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2225
Met Thr Ala Gln Gly Ala Xaa Leu Ala Asn Arg Gly Arg Arg Phe Lys
  1               5                  10                  15

Trp Ala Ile Glu Leu Ser Gly Pro Gly Gly Gly Ser Arg Gly Arg Ser
             20                  25                  30

Asp Arg Gly Ser Gly Gln Gly Asp Ser Leu Tyr Pro Val Gly Tyr Leu
         35                  40                  45

Asp Lys Gln Val Pro Asp Thr Ser Val Gln Glu Thr Asp Arg Ile Leu
     50                  55                  60

Val Glu Lys Arg Cys Trp Asp Ile Ala Leu Gly Pro Leu Lys Gln Ile
 65                  70                  75                  80

Pro Met Asn Leu Phe Ile Met Tyr Met Ala Gly Asn Thr Ile Ser Ile
                 85                  90                  95

Phe Pro Thr Met Met Val Cys Met Met Ala Trp Arg Pro Ile Gln Ala
            100                 105                 110

Leu Met Ala Ile Ser Ala Thr Phe Lys Met Leu Glu Ser Ser Ser Gln
        115                 120                 125

Lys Phe Leu Gln Gly Leu Val Tyr Leu Ile Gly Asn Leu Met Gly Leu
    130                 135                 140

Ala Leu Ala Val Tyr Lys Cys Gln Ser Met Gly Leu Leu Pro Thr His
145                 150                 155                 160

Ala Ser Asp Trp Leu Ala Phe Ile Glu Pro Pro Glu Arg Met Glu Phe
                165                 170                 175

Ser Gly Gly Gly Leu Leu Leu 
            180



<210> 2226
<211> 153
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2226
Met Glu Glu Gly Gly Asn Leu Gly Gly Leu Ile Lys Met Val His Leu
  1               5                  10                  15

Leu Val Leu Ser Gly Ala Trp Gly Met Gln Met Trp Val Thr Phe Val
             20                  25                  30

Ser Gly Phe Leu Leu Phe Arg Ser Leu Pro Arg His Thr Phe Gly Leu
         35                  40                  45

Val Gln Ser Lys Leu Phe Pro Phe Tyr Phe His Ile Ser Met Gly Cys
     50                  55                  60

Ala Phe Ile Asn Leu Cys Ile Leu Ala Ser Gln His Ala Trp Ala Gln
 65                  70                  75                  80

Leu Thr Phe Trp Glu Ala Ser Gln Leu Tyr Leu Leu Phe Leu Ser Leu
                 85                  90                  95

Thr Leu Ala Thr Val Asn Ala Arg Trp Leu Glu Pro Arg Thr Thr Ala
            100                 105                 110

Ala Met Trp Ala Leu Gln Thr Val Glu Lys Glu Xaa Gly Leu Gly Gly
        115                 120                 125

Glu Val Pro Xaa Ser His Gln Gly Pro Asp Pro Tyr Arg Gln Leu Arg
    130                 135                 140

Glu Lys Asp Pro Lys Tyr Ser Ala Leu 
145                 150



<210> 2227
<211> 206
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2227
Met Ile Cys Asp Thr Asp Pro Glu Leu Gly Gly Ala Val Gln Leu Met
  1               5                  10                  15

Gly Leu Leu Arg Thr Leu Val Asp Pro Glu Asn Met Leu Ala Thr Ala
             20                  25                  30

Asn Lys Thr Glu Lys Thr Glu Phe Leu Gly Phe Phe Tyr Lys His Cys
         35                  40                  45

Met His Val Leu Thr Ala Pro Leu Leu Ala Asn Thr Thr Glu Asp Lys
     50                  55                  60

Pro Ser Lys Asp Asp Phe Gln Thr Ala Gln Leu Leu Ala Leu Val Leu
 65                  70                  75                  80

Glu Leu Leu Thr Phe Cys Val Glu His His Thr Tyr His Ile Lys Asn
                 85                  90                  95

Tyr Ile Ile Asn Lys Asp Ile Leu Arg Arg Val Leu Val Leu Met Ala
            100                 105                 110

Ser Lys His Ala Phe Xaa Ala Leu Cys Ala Leu Arg Phe Lys Arg Lys
        115                 120                 125

Ile Ile Gly Leu Lys Asp Glu Phe Tyr Asn Arg Tyr Ile Met Lys Ser
    130                 135                 140

Phe Leu Phe Glu Pro Val Val Lys Ala Phe Leu Asn Asn Gly Ser Arg
145                 150                 155                 160

Tyr Asn Leu Met Asn Ser Ala Ile Ile Glu Met Val Glu Phe Ile Arg
                165                 170                 175

Val Glu Asp Ile Lys Ser Leu Thr Ala His Val Ile Glu Xaa Tyr Trp
            180                 185                 190

Lys Ala Leu Glu Asp Val Asp Tyr Val Arg His Leu Lys Asp 
        195                 200                 205



<210> 2228
<211> 277
<212> PRT
<213> Homo sapiens

<400> 2228
Met Asn Gln Thr Gln Ser Leu Pro Gly Val Ala Gln Arg Ser Gly Gly
  1               5                  10                  15

Glu Arg His Arg Glu Asn Ser Pro Ser Pro Gly Gly Lys Glu Ala Glu
             20                  25                  30

Thr Arg Gln Pro Val Val Ile Leu Leu Gly Trp Gly Gly Cys Lys Asp
         35                  40                  45

Lys Asn Leu Ala Lys Tyr Ser Ala Ile Tyr His Lys Arg Gly Cys Ile
     50                  55                  60

Val Ile Arg Tyr Thr Ala Pro Trp His Met Val Phe Phe Ser Glu Ser
 65                  70                  75                  80

Leu Gly Ile Pro Ser Leu Arg Val Leu Ala Gln Lys Leu Leu Glu Leu
                 85                  90                  95

Leu Phe Asp Tyr Glu Ile Glu Lys Glu Pro Leu Leu Phe His Val Phe
            100                 105                 110

Ser Asn Gly Gly Val Met Leu Tyr Arg Tyr Val Leu Glu Leu Leu Gln
        115                 120                 125

Thr Arg Arg Phe Cys Arg Leu Arg Val Val Gly Thr Ile Phe Asp Ser
    130                 135                 140

Ala Pro Gly Asp Ser Asn Leu Val Gly Ala Leu Arg Ala Leu Ala Ala
145                 150                 155                 160

Ile Leu Glu Arg Arg Ala Ala Met Leu Arg Leu Leu Leu Leu Val Ala
                165                 170                 175

Phe Ala Leu Val Val Val Leu Phe His Val Leu Leu Ala Pro Ile Thr
            180                 185                 190

Ala Leu Phe His Thr His Phe Tyr Asp Arg Leu Gln Asp Ala Gly Ser
        195                 200                 205

Arg Trp Pro Glu Leu Tyr Leu Tyr Ser Arg Ala Asp Glu Val Val Leu
    210                 215                 220

Ala Arg Asp Ile Glu Arg Met Val Glu Ala Arg Leu Ala Arg Arg Val
225                 230                 235                 240

Leu Ala Arg Ser Val Asp Phe Val Ser Ser Ala His Val Ser His Leu
                245                 250                 255

Arg Asp Tyr Pro Thr Tyr Tyr Thr Ser Leu Cys Val Asp Phe Met Arg
            260                 265                 270

Asn Cys Val Arg Cys 
        275



<210> 2229
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2229
Met Ala Ser His Val Glu Cys Arg Pro Leu Gly Val Phe Glu Cys Glu
  1               5                  10                  15

Leu Cys Thr Leu Thr Ala Pro Tyr Ser Tyr Val Gly Gln Lys Pro Pro
             20                  25                  30

Asn Thr Gln Ser Met Val Leu Leu Glu Glu Ser Tyr Val Met Lys Asp
         35                  40                  45

Pro Xaa Thr Ser Asp Lys Asp Arg Phe Leu Val Leu Gly Ser Cys Cys
     50                  55                  60

Ser Leu Cys Ser Arg Leu Val Cys Val Gly Pro Glu Cys Ser Leu Phe
 65                  70                  75                  80

Tyr Ser Arg Asp Ser Ala Xaa Leu Val Ser Gly Arg Thr Ser Met Leu
                 85                  90                  95

Phe Leu Arg Lys Phe Gly Lys Thr Trp Arg Lys Gly Lys Leu His Gln
            100                 105                 110

Arg Gly Pro Pro Ala Ser Pro Val Leu Gly Arg Glu Cys Asn Trp Gly
        115                 120                 125






<210> 2230
<211> 578
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2230
Met Glu Pro Asp Val Pro Leu Pro Gln Thr Leu Leu Ser His Pro Ser
  1               5                  10                  15

Tyr Leu Lys Val Phe Val Pro Asp Tyr Thr Arg Glu Leu Leu Leu Glu
             20                  25                  30

Leu Arg Asp Cys Val Ser Asn Gly Ser Leu Gly Cys Pro Val Arg Leu
         35                  40                  45

Thr Val Gly Pro Val Thr Leu Pro Ser Asn Phe Gln Lys Val Leu Thr
     50                  55                  60

Cys Thr Gly Ala Pro Trp Pro Cys Arg Leu Leu Leu Pro Ser Pro Pro
 65                  70                  75                  80

Trp Asp Arg Trp Leu Gln Val Thr Ala Glu Ser Leu Val Gly Pro Leu
                 85                  90                  95

Gly Thr Val Ala Phe Ser Ala Val Ala Ala Leu Thr Ala Cys Arg Pro
            100                 105                 110

Arg Ser Val Thr Xaa Gln Pro Leu Leu Gln Ser Xaa Gln Asn Gln Ser
        115                 120                 125

Phe Asn Ala Ser Ser Gly Leu Leu Ser Pro Ser Pro Asp His Gln Asp
    130                 135                 140

Leu Gly Arg Ser Gly Arg Val Asp Arg Ser Pro Phe Cys Leu Thr Asn
145                 150                 155                 160

Tyr Pro Val Thr Arg Glu Asp Met Asp Val Val Ser Val His Phe Gln
                165                 170                 175

Pro Leu Asp Arg Val Ser Val Arg Val Cys Ser Asp Thr Pro Ser Val
            180                 185                 190

Met Arg Leu Arg Leu Asn Thr Gly Met Asp Ser Gly Gly Ser Leu Thr
        195                 200                 205

Ile Ser Leu Arg Ala Asn Lys Thr Glu Met Arg Asn Glu Thr Val Val
    210                 215                 220

Val Ala Cys Val Asn Ala Ala Ser Pro Phe Leu Gly Phe Asn Thr Ser
225                 230                 235                 240

Leu Asn Cys Thr Thr Ala Phe Phe Gln Gly Tyr Pro Leu Ser Leu Ser
                245                 250                 255

Ala Trp Ser Arg Arg Ala Asn Leu Ile Ile Pro Tyr Pro Glu Thr Asp
            260                 265                 270

Asn Trp Tyr Leu Ser Leu Gln Leu Met Cys Pro Glu Asn Ala Glu Asp
        275                 280                 285

Cys Glu Gln Ala Val Val His Val Glu Thr Thr Leu Tyr Leu Val Pro
    290                 295                 300

Cys Leu Asn Asp Cys Gly Pro Tyr Gly Gln Cys Leu Leu Leu Arg Arg
305                 310                 315                 320

His Ser Tyr Leu Tyr Ala Ser Cys Ser Cys Lys Ala Gly Trp Arg Gly
                325                 330                 335

Trp Ser Cys Thr Asp Asn Ser Thr Ala Gln Thr Val Ala Gln Gln Arg
            340                 345                 350

Ala Ala Thr Leu Leu Leu Thr Leu Ser Asn Leu Met Phe Leu Ala Pro
        355                 360                 365

Ile Ala Val Ser Val Arg Arg Phe Phe Leu Val Glu Ala Ser Val Tyr
    370                 375                 380

Ala Tyr Thr Met Phe Phe Ser Thr Phe Tyr His Ala Cys Asp Gln Pro
385                 390                 395                 400

Gly Glu Ala Val Leu Cys Ile Leu Ser Tyr Asp Thr Leu Gln Tyr Cys
                405                 410                 415

Asp Phe Leu Gly Ser Gly Ala Ala Ile Trp Val Thr Ile Leu Cys Met
            420                 425                 430

Ala Arg Leu Lys Thr Val Leu Lys Tyr Val Leu Phe Leu Leu Gly Thr
        435                 440                 445

Leu Val Ile Ala Met Ser Leu Gln Leu Asp Arg Arg Gly Met Trp Asn
    450                 455                 460

Met Leu Gly Pro Cys Leu Phe Ala Phe Val Ile Met Ala Ser Met Trp
465                 470                 475                 480

Ala Tyr Arg Cys Gly His Arg Arg Gln Cys Tyr Pro Thr Ser Trp Gln
                485                 490                 495

Arg Trp Ala Phe Tyr Leu Leu Pro Gly Val Ser Met Ala Ser Val Gly
            500                 505                 510

Ile Ala Ile Tyr Thr Ser Met Met Thr Ser Asp Asn Tyr Tyr Tyr Thr
        515                 520                 525

His Ser Ile Trp His Ile Leu Leu Ala Gly Ser Ala Ala Leu Leu Leu
    530                 535                 540

Pro Pro Pro Asp Gln Pro Ala Glu Pro Trp Ala Cys Ser Gln Lys Phe
545                 550                 555                 560

Pro Cys His Tyr Gln Ile Cys Lys Asn Asp Arg Glu Glu Leu Tyr Ala
                565                 570                 575

Val Thr 




<210> 2231
<211> 179
<212> PRT
<213> Homo sapiens

<400> 2231
Met Val Leu Phe Pro Gly Glu Ala Val Val Arg Pro Met Ala Pro Arg
  1               5                  10                  15

Ser Pro Glu Pro Thr Thr Gly Ala Gly Ser Cys Gly Leu Arg Asp Pro
             20                  25                  30

Cys Ser Trp Pro Leu Cys Gly Pro Asp Ala Ser Leu Pro Gly Ala Trp
         35                  40                  45

Arg Ile Pro Leu Cys Cys Cys Gly His His Arg Asp Gly Arg Arg Arg
     50                  55                  60

Phe Pro Pro Glu Leu Met Gly Thr Gly Asp Ala Gly Ser Arg Pro Ala
 65                  70                  75                  80

Pro Pro Phe Phe Leu Ala Leu Glu Pro Trp Val Pro Glu Lys Ser Phe
                 85                  90                  95

Leu Gly Leu Gly Cys Ser Ala Ala Leu Gly Val Trp Pro Arg Arg Asn
            100                 105                 110

Pro Tyr Pro Ala Leu Ser Thr His Pro Ser Val Pro Gly Pro Pro Ser
        115                 120                 125

Gly Ser Phe Leu Leu Val Pro Gly Ala Ala Val Val Ser Ala Pro Cys
    130                 135                 140

Thr Gly Leu Cys Ala Leu Trp Val Phe Arg Arg Leu Asp Cys Leu Cys
145                 150                 155                 160

Ser Ser Cys Lys Pro Cys Gly Gly Ser Asn Asp Gln Glu Gln His Leu
                165                 170                 175

Ala Pro Pro 




<210> 2232
<211> 116
<212> PRT
<213> Homo sapiens

<400> 2232
Met Pro His Ser Cys Asp Lys Ser Thr Thr Ile Leu Lys Leu Leu Glu
  1               5                  10                  15

His Gly Leu Ser Ser Ser Ser Leu Trp Pro Leu Leu Pro Trp Gly His
             20                  25                  30

Leu Gly Pro Ala Pro Leu Ser His Phe Gln Ser Ser Ser Phe Pro Ile
         35                  40                  45

Trp Ala Phe Ile Lys Cys Arg Gly Ser Gln Thr Gly Leu Arg Ser Ala
     50                  55                  60

Lys Ala Leu Pro Trp Gly Val Val Phe Leu Gly Leu Ala Leu Leu Phe
 65                  70                  75                  80

Arg Thr Trp Asp His Asn Gly Val Pro Ala Glu Gly Val Pro Lys Arg
                 85                  90                  95

Ser Arg Leu Ser Cys Asp Leu Trp Trp His Val Leu Cys Ile Cys Trp
            100                 105                 110

Leu Leu Val Ser 
        115



<210> 2233
<211> 192
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2233
Met Asp Ala Pro Arg Leu Pro Val Arg Pro Gly Val Leu Leu Pro Asn
  1               5                  10                  15

Trp Xaa Cys Ser Leu Ser Thr Gln Met Ile Ala Leu Leu Ser Val Gly
             20                  25                  30

Lys Asp Cys Lys Ser Tyr Cys Cys Asp Gly Xaa Thr Pro Tyr Cys Cys
         35                  40                  45

Ser Xaa Tyr Ala Tyr Ile Gly Asn Ile Leu Ser Gly Thr Ala Ile Ala
     50                  55                  60

Gly Ile Val Phe Gly Ile Ile Phe Ile Met Gly Val Ile Ala Gly Ile
 65                  70                  75                  80

Ala Ile Cys Ile Cys Met Cys Met Lys Asn Thr Gly Arg Pro Arg Gly
                 85                  90                  95

His Pro Gln Asp Asp Ser His Gln His Arg Leu Leu Leu Ser Trp Xaa
            100                 105                 110

Thr Thr Leu Arg Ser Xaa Pro Arg Asp Gly Ile Leu Cys Arg Leu Ala
        115                 120                 125

Ser Ser Ile Leu Pro His Pro Thr Gly Ser Ser Thr Ala Phe Ser Thr
    130                 135                 140

Pro Ser Leu Ser Trp Lys Arg Lys Glu Ile Ile Tyr Leu Pro Glu Gln
145                 150                 155                 160

Asn Met Cys Gln Trp Ala Ile Leu Pro Gly Ile Lys Cys Leu Tyr Ser
                165                 170                 175

Glu Thr Gly Arg Lys Glu Leu Leu Gln Gly Ile Leu Phe Gly Val Arg
            180                 185                 190






<210> 2234
<211> 182
<212> PRT
<213> Homo sapiens

<400> 2234
Met Arg Ile Arg Tyr Gly Trp Glu Leu Ala Leu Ala Ala Leu Leu Val
  1               5                  10                  15

Ile Glu Ile Val Ala Phe Gly Ala Ile Asn Pro Arg Met Leu Asp Leu
             20                  25                  30

Asn Met Leu Leu Phe Ser Thr Ser Asp Phe Ile Cys Ile Gly Ile Val
         35                  40                  45

Ala Leu Pro Leu Thr Met Val Ile Val Ser Gly Gly Ile Asp Ile Ser
     50                  55                  60

Phe Gly Ser Thr Ile Gly Leu Cys Ala Ile Ala Leu Gly Val Leu Phe
 65                  70                  75                  80

Gln Ser Gly Val Pro Met Pro Leu Ala Ile Leu Leu Thr Leu Leu Leu
                 85                  90                  95

Gly Ala Leu Cys Gly Leu Ile Asn Ala Gly Leu Ile Ile Tyr Thr Lys
            100                 105                 110

Val Asn Pro Leu Val Ile Thr Leu Gly Thr Leu Tyr Leu Phe Ala Gly
        115                 120                 125

Ser Ala Leu Leu Leu Ser Gly Met Ala Gly Ala Thr Gly Tyr Glu Gly
    130                 135                 140

Ile Gly Gly Phe Pro Met Ala Phe Thr Asp Phe Ala Asn Leu Asp Val
145                 150                 155                 160

Leu Gly Leu Pro Val Pro Leu Ile Ile Phe Leu Ile Met Ser Pro Arg
                165                 170                 175

Phe Leu Ala Leu Ala Ala 
            180



<210> 2235
<211> 119
<212> PRT
<213> Homo sapiens

<400> 2235
Met Gln Phe Cys Phe Tyr Leu Ser Cys Leu Gly Ile Ile Lys Leu Tyr
  1               5                  10                  15

Gln Phe Trp Lys Val Leu Ser Leu Tyr Leu Phe Asn Cys Ser Phe Cys
             20                  25                  30

Pro Ile Phe Leu Pro Ser Ser Lys Thr Pro Val Thr Tyr Val Leu Gly
         35                  40                  45

Leu Phe Thr Thr Ser His Lys Tyr Leu Met Phe Phe Ala Val Phe Ser
     50                  55                  60

Ile Leu Phe Val Ser Val Phe Gln Leu Arg Val Phe Ile Leu Ser Cys
 65                  70                  75                  80

Ile Thr Val Gln Arg Met Phe Leu Leu Leu Asn Leu Ile Val Val Asn
                 85                  90                  95

Pro Tyr Ala Lys Tyr Leu Ile Ser Val Ile Val Phe Leu Ser Phe Lys
            100                 105                 110

Phe Pro Phe His Ser Phe Leu 
        115



<210> 2236
<211> 221
<212> PRT
<213> Homo sapiens

<400> 2236
Met Ile Gly Met Ser Thr Lys Ala Val Leu Trp Arg Cys Phe Ser Thr
  1               5                  10                  15

Val Val Ile Phe Leu Phe Leu Leu Asp Glu Gln Thr Ser Leu Leu Val
             20                  25                  30

Leu Val Pro Ala Gly Val Gly Ala Ala Ile Glu Leu Trp Lys Val Lys
         35                  40                  45

Lys Ala Leu Lys Met Thr Ile Phe Trp Arg Gly Leu Met Pro Glu Phe
     50                  55                  60

Gln Phe Gly Thr Tyr Ser Glu Ser Glu Arg Lys Thr Glu Glu Tyr Asp
 65                  70                  75                  80

Thr Gln Ala Met Lys Tyr Leu Ser Tyr Leu Leu Tyr Pro Leu Cys Val
                 85                  90                  95

Gly Gly Ala Val Tyr Ser Leu Leu Asn Ile Lys Tyr Lys Ser Trp Tyr
            100                 105                 110

Ser Trp Leu Ile Asn Ser Phe Val Asn Gly Val Tyr Ala Phe Gly Phe
        115                 120                 125

Leu Phe Met Leu Pro Gln Leu Phe Val Asn Tyr Lys Leu Lys Ser Val
    130                 135                 140

Ala His Leu Pro Trp Lys Ala Phe Thr Tyr Lys Ala Phe Asn Thr Phe
145                 150                 155                 160

Ile Asp Asp Val Phe Ala Phe Ile Ile Thr Met Pro Thr Ser His Arg
                165                 170                 175

Leu Ala Cys Phe Arg Asp Asp Val Val Phe Leu Val Tyr Leu Tyr Gln
            180                 185                 190

Arg Trp Leu Tyr Pro Val Asp Lys Arg Arg Val Asn Glu Phe Gly Glu
        195                 200                 205

Ser Tyr Glu Glu Lys Ala Thr Arg Ala Pro His Thr Asp 
    210                 215                 220



<210> 2237
<211> 103
<212> PRT
<213> Homo sapiens

<400> 2237
Met Ile Asn Phe Thr Ser Gly Ala Leu Ser Gly Ser Phe Ala Ala Val
  1               5                  10                  15

Ala Thr Leu Pro Phe Asp Val Val Lys Thr Gln Lys Gln Thr Gln Leu
             20                  25                  30

Trp Thr Tyr Glu Ser His Lys Ile Ser Met Pro Leu His Met Ser Thr
         35                  40                  45

Trp Ile Ile Met Lys Asn Ile Val Ala Lys Asn Gly Phe Ser Gly Leu
     50                  55                  60

Phe Ser Gly Leu Ile Pro Arg Leu Ile Lys Ile Ala Pro Ala Cys Ala
 65                  70                  75                  80

Ile Met Ile Ser Thr Tyr Glu Phe Gly Lys Ala Phe Phe Gln Lys Gln
                 85                  90                  95

Asn Val Arg Arg Gln Gln Tyr 
            100



<210> 2238
<211> 486
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (276)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2238
Met Arg Arg Leu Val His Asp Leu Leu Pro Pro Glu Val Cys Ser Leu
  1               5                  10                  15

Leu Asn Pro Ala Ala Ile Tyr Ala Asn Asn Glu Ile Ser Leu Arg Asp
             20                  25                  30

Val Glu Val Tyr Gly Phe Asp Tyr Asp Tyr Thr Leu Ala Gln Tyr Ala
         35                  40                  45

Asp Ala Leu His Pro Glu Ile Phe Ser Thr Ala Arg Asp Ile Leu Ile
     50                  55                  60

Glu His Tyr Lys Tyr Pro Glu Gly Ile Arg Lys Tyr Asp Tyr Asn Pro
 65                  70                  75                  80

Ser Phe Ala Ile Arg Gly Leu His Tyr Asp Ile Gln Lys Ser Leu Leu
                 85                  90                  95

Met Lys Ile Asp Ala Phe His Tyr Val Gln Leu Gly Thr Ala Tyr Arg
            100                 105                 110

Gly Leu Gln Pro Val Pro Asp Glu Glu Val Ile Glu Leu Tyr Gly Gly
        115                 120                 125

Thr Gln His Ile Pro Leu Tyr Gln Met Ser Gly Phe Tyr Gly Lys Gly
    130                 135                 140

Pro Ser Ile Lys Gln Phe Met Asp Ile Phe Ser Leu Pro Glu Met Ala
145                 150                 155                 160

Leu Leu Ser Cys Val Val Asp Tyr Phe Leu Gly His Ser Leu Glu Phe
                165                 170                 175

Asp Gln Ala His Leu Tyr Lys Asp Val Thr Asp Ala Ile Arg Asp Val
            180                 185                 190

His Val Lys Gly Leu Met Tyr Gln Trp Ile Glu Gln Asp Met Glu Lys
        195                 200                 205

Tyr Ile Leu Arg Gly Asp Glu Thr Phe Ala Val Leu Ser Arg Leu Val
    210                 215                 220

Ala His Gly Lys Gln Leu Phe Leu Ile Thr Asn Ser Pro Phe Ser Phe
225                 230                 235                 240

Val Asp Lys Gly Met Arg His Met Val Gly Pro Asp Trp Arg Gln Leu
                245                 250                 255

Phe Asp Val Val Ile Val Gln Ala Asp Lys Pro Ser Phe Phe Thr Asp
            260                 265                 270

Arg Arg Lys Xaa Phe Arg Lys Leu Asp Glu Lys Gly Ser Leu Gln Trp
        275                 280                 285

Asp Arg Ile Thr Arg Leu Glu Lys Gly Lys Ile Tyr Arg Gln Gly Asn
    290                 295                 300

Leu Phe Asp Phe Leu Arg Leu Thr Glu Trp Arg Gly Pro Arg Val Leu
305                 310                 315                 320

Tyr Phe Gly Asp His Leu Tyr Ser Asp Leu Ala Asp Leu Met Leu Arg
                325                 330                 335

His Gly Trp Arg Thr Gly Ala Ile Ile Pro Glu Leu Glu Arg Glu Ile
            340                 345                 350

Arg Ile Ile Asn Thr Glu Gln Tyr Met His Ser Leu Thr Trp Gln Gln
        355                 360                 365

Ala Leu Thr Gly Leu Leu Glu Arg Met Gln Thr Tyr Gln Asp Ala Glu
    370                 375                 380

Ser Arg Gln Val Leu Ala Ala Trp Met Lys Glu Arg Gln Glu Leu Arg
385                 390                 395                 400

Cys Ile Thr Lys Ala Leu Phe Asn Ala Gln Phe Gly Ser Ile Phe Arg
                405                 410                 415

Thr Phe His Asn Pro Thr Tyr Phe Ser Arg Arg Leu Val Arg Phe Ser
            420                 425                 430

Asp Leu Tyr Met Ala Ser Leu Ser Cys Leu Leu Asn Tyr Arg Val Asp
        435                 440                 445

Phe Thr Phe Tyr Pro Arg Arg Thr Pro Leu Gln His Glu Ala Pro Leu
    450                 455                 460

Trp Met Asp Gln Leu Cys Thr Gly Cys Met Lys Thr Pro Phe Leu Gly
465                 470                 475                 480

Asp Met Ala His Ile Arg 
                485



<210> 2239
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2239
Met Met Pro Ser Val Leu Leu Arg Gln Ile Arg Ala Leu Xaa Arg Arg
  1               5                  10                  15

Val Pro Ala Pro Cys Gln Ala Pro Thr Phe His Arg Pro Pro Leu Met
             20                  25                  30

Ser Gln Ala Ala Thr Asn Thr Val Ile Val Thr Asn Ser Glu Asn Ala
         35                  40                  45

Arg Ser Trp Ile Lys Asp Ser Gln Thr His Gln Trp Arg Leu Gly Glu
     50                  55                  60

Pro Ile Glu Leu Arg Arg Ala Met Asn Val Ile His Gly Asp Gly Gly
 65                  70                  75                  80

Gly Leu Ser Gly Gly Ala Ala Ala Gly Val Thr Val Gly Val Thr Thr
                 85                  90                  95

Ile Leu Ala Val Val Ile Thr Leu Ala Ile Tyr Gly Thr Arg Lys Phe
            100                 105                 110

Lys Lys Lys Ala Tyr Gln Ala Ile Glu Glu Arg Gln Ser Leu Val Pro
        115                 120                 125

Gly Thr Ala Ala Thr Gly Asp Thr Thr Tyr Gln Glu Gln Gly Gln Ser
    130                 135                 140

Pro Ala 
145



<210> 2240
<211> 188
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (181)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2240
Met Asp Gly Thr Glu Thr Arg Gln Arg Xaa Leu Asp Ser Cys Gly Lys
  1               5                  10                  15

Pro Gly Glu Leu Gly Leu Pro His Pro Leu Ser Thr Gly Gly Leu Pro
             20                  25                  30

Val Ala Ser Glu Asp Gly Ala Leu Arg Ala Pro Glu Ser Gln Ser Val
         35                  40                  45

Thr Pro Lys Pro Leu Glu Thr Glu Pro Ser Arg Glu Thr Ala Trp Ser
     50                  55                  60

Ile Gly Leu Gln Val Thr Val Pro Phe Met Phe Ala Gly Leu Gly Leu
 65                  70                  75                  80

Ser Trp Ala Gly Met Leu Leu Asp Tyr Phe Gln His Trp Pro Val Phe
                 85                  90                  95

Val Glu Val Lys Asp Leu Leu Thr Leu Val Pro Pro Leu Val Gly Leu
            100                 105                 110

Lys Gly Asn Leu Glu Met Thr Leu Ala Ser Arg Leu Ser Thr Ala Ala
        115                 120                 125

Asn Thr Gly Gln Ile Asp Asp Pro Gln Glu Gln His Arg Val Ile Ser
    130                 135                 140

Ser Asn Leu Ala Leu Ile Gln Val Gln Ala Thr Val Val Gly Leu Leu
145                 150                 155                 160

Ala Ala Val Ala Ala Leu Leu Leu Gly Val Val Ser Arg Arg Gly Ser
                165                 170                 175

Gly Cys Arg Gln Xaa Gly Val Leu Cys Xaa Ser Ser 
            180                 185



<210> 2241
<211> 409
<212> PRT
<213> Homo sapiens

<400> 2241
Met Val Ile Leu Glu Val Ala Cys Glu Pro Ile Arg Arg Tyr Leu Arg
  1               5                  10                  15

Thr Arg Glu Asp Thr Val Arg Gln Ile Val Ala Gly Leu Thr Gly Asp
             20                  25                  30

Ser Asp Gly Thr Gly Asp Leu Ala Val Glu Leu Ser Lys Thr Asp Pro
         35                  40                  45

Ala Ser Leu Glu Thr Gly Gln Asp Ser Glu Asp Asp Ser Gly Glu Pro
     50                  55                  60

Glu Asp Trp Val Pro Asp Pro Val Asp Ala Asp Pro Gly Lys Ser Ser
 65                  70                  75                  80

Ser Lys Arg Arg Ser Ser Asp Ile Ile Ser Leu Leu Val Ser Ile Tyr
                 85                  90                  95

Gly Ser Lys Asp Leu Phe Ile Asn Glu Tyr Arg Ser Leu Leu Ala Asp
            100                 105                 110

Arg Leu Leu His Gln Phe Ser Phe Ser Pro Glu Arg Glu Ile Arg Asn
        115                 120                 125

Val Glu Leu Leu Lys Leu Arg Phe Gly Glu Ala Pro Met His Phe Cys
    130                 135                 140

Glu Val Met Leu Lys Asp Met Ala Asp Ser Arg Arg Ile Asn Ala Asn
145                 150                 155                 160

Ile Arg Glu Glu Asp Glu Lys Arg Pro Ala Glu Glu Gln Pro Pro Phe
                165                 170                 175

Gly Val Tyr Ala Val Ile Leu Ser Ser Glu Phe Trp Pro Pro Phe Lys
            180                 185                 190

Asp Glu Lys Leu Glu Val Pro Glu Asp Ile Arg Ala Ala Leu Glu Ala
        195                 200                 205

Tyr Cys Lys Lys Tyr Glu Gln Leu Lys Ala Met Arg Thr Leu Ser Trp
    210                 215                 220

Lys His Thr Leu Gly Leu Val Thr Met Asp Val Glu Leu Ala Asp Arg
225                 230                 235                 240

Thr Leu Ser Val Ala Val Thr Pro Val Gln Ala Val Ile Leu Leu Tyr
                245                 250                 255

Phe Gln Asp Gln Ala Ser Trp Thr Leu Glu Glu Leu Ser Lys Ala Val
            260                 265                 270

Lys Met Pro Val Ala Leu Leu Arg Arg Arg Met Ser Val Trp Leu Gln
        275                 280                 285

Gln Gly Val Leu Arg Glu Glu Pro Pro Gly Thr Phe Ser Val Ile Glu
    290                 295                 300

Glu Glu Arg Pro Gln Asp Arg Asp Asn Met Val Leu Ile Asp Ser Asp
305                 310                 315                 320

Asp Glu Ser Asp Ser Gly Met Ala Ser Gln Ala Asp Gln Lys Glu Glu
                325                 330                 335

Glu Leu Leu Leu Phe Trp Thr Tyr Ile Gln Ala Met Leu Thr Asn Leu
            340                 345                 350

Glu Ser Leu Ser Leu Asp Arg Ile Tyr Asn Met Leu Arg Met Phe Val
        355                 360                 365

Val Thr Gly Pro Ala Leu Ala Glu Ile Asp Leu Gln Glu Leu Gln Gly
    370                 375                 380

Tyr Leu Gln Lys Lys Val Arg Asp Gln Gln Leu Val Tyr Ser Ala Gly
385                 390                 395                 400

Val Tyr Arg Leu Pro Lys Asn Cys Ser 
                405



<210> 2242
<211> 101
<212> PRT
<213> Homo sapiens

<400> 2242
Met Lys Thr Ile Ser Pro Phe Pro Ala Leu Asn Val Leu Leu Ala Leu
  1               5                  10                  15

Gly Ala His His Ala Thr Glu Glu Asn Val Glu Thr Gln Lys Val Arg
             20                  25                  30

Thr Asp Phe Gln Ala Leu Ala Thr Asp Val Thr Val Phe Asn Phe Asn
         35                  40                  45

Asn Tyr Thr Tyr Leu Tyr Ile Ser Glu Lys Phe Leu Ile Phe Leu Cys
     50                  55                  60

Pro Leu Phe Ile Ser Phe Lys Met Ile Phe Ser Ala Leu Arg Phe Ala
 65                  70                  75                  80

Ser Arg Lys Ser Thr Ser Leu His Leu Lys Ala Leu Lys Thr Arg Asp
                 85                  90                  95

Thr Leu Tyr Thr Phe 
            100



<210> 2243
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2243
Met Leu Gln Gly His Arg Pro Arg Val Trp Gln Gln Thr Gly Ala Ala
  1               5                  10                  15

Val Val Thr Gly Ala Trp Ser Leu Leu Asp Met Thr Ser Cys Gly His
             20                  25                  30

Ala Pro Thr Val Ser Leu Cys Ala Ser Arg Leu Cys Arg Cys Leu Cys
         35                  40                  45

Thr Arg Ser Arg Ser Thr Ser Phe Ile Ser Thr Xaa Met Leu Gly Leu
     50                  55                  60

Arg Gln Lys Leu Thr Thr Ser Leu Thr Ser Ala Ala Xaa Leu Thr Cys
 65                  70                  75                  80

Val Leu Leu Leu Ser Met Thr Gly Met Thr Thr Ser Ser Ser Arg Ala
                 85                  90                  95

Phe Cys Gly Arg Pro Glu Glu Arg Tyr Tyr His Ile Cys Xaa Lys Xaa
            100                 105                 110

Ala Asn Val Arg Xaa Val Gln Gly Xaa Asp Leu Lys Ile Pro Ser Ile
        115                 120                 125






<210> 2244
<211> 236
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (212)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2244
Met Lys Arg Ser Gly Asn Pro Gly Ala Glu Val Thr Asn Ser Ser Val
  1               5                  10                  15

Ala Gly Pro Asp Cys Cys Gly Gly Leu Gly Asn Ile Asp Phe Arg Gln
             20                  25                  30

Ala Asp Phe Cys Val Met Thr Arg Leu Leu Gly Tyr Val Asp Pro Leu
         35                  40                  45

Asp Pro Ser Phe Val Ala Ala Val Ile Thr Ile Thr Phe Asn Pro Leu
     50                  55                  60

Tyr Trp Asn Val Val Ala Arg Trp Glu His Lys Thr Arg Lys Leu Ser
 65                  70                  75                  80

Arg Ala Phe Gly Ser Pro Tyr Leu Ala Cys Tyr Ser Leu Ser Xaa Thr
                 85                  90                  95

Ile Leu Leu Leu Asn Phe Leu Arg Ser His Cys Phe Thr Gln Ala Met
            100                 105                 110

Leu Ser Gln Pro Arg Met Glu Ser Leu Asp Thr Pro Ala Ala Tyr Ser
        115                 120                 125

Leu Gly Leu Ala Leu Leu Gly Leu Gly Val Val Leu Val Leu Ser Ser
    130                 135                 140

Phe Phe Ala Leu Gly Phe Ala Gly Thr Phe Leu Gly Asp Tyr Phe Gly
145                 150                 155                 160

Ile Leu Lys Glu Ala Arg Val Thr Val Phe Pro Phe Asn Ile Leu Asp
                165                 170                 175

Asn Pro Met Tyr Trp Gly Ser Thr Ala Asn Tyr Leu Gly Trp Ala Ile
            180                 185                 190

Met His Ala Ser Pro Thr Gly Leu Leu Leu Thr Val Leu Val Ala Leu
        195                 200                 205

Thr Tyr Ile Xaa Ala Leu Leu Tyr Glu Glu Pro Phe Thr Ala Glu Ile
    210                 215                 220

Tyr Arg Gln Lys Ala Ser Gly Ser His Lys Arg Ser 
225                 230                 235



<210> 2245
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (164)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2245
Met Ala Trp Ser Ser Pro Ala Ala Xaa Leu Arg Phe Leu Phe Arg Gln
  1               5                  10                  15

Leu Leu Leu Ala Thr Gln Gly Gly Pro Lys Gly Lys Glu Gln Ser Val
             20                  25                  30

Leu Ala Pro Gln Pro Gly Pro Gly Pro Pro Phe Thr Leu Lys Pro Arg
         35                  40                  45

Val Phe Leu His Leu Tyr Ile Ser Asn Thr Pro Lys Gly Ala Ala Arg
     50                  55                  60

Asp Ile Tyr Leu Pro Pro Thr Ser Glu Gly Gly Leu Pro His Ser Pro
 65                  70                  75                  80

Pro Met Arg Leu Gln Ala His Val Leu Gly Gln Leu Lys Pro Val Cys
                 85                  90                  95

Tyr Val Ala Pro Ser Leu Cys Asp Thr His Val Gly Cys Leu Ser Ala
            100                 105                 110

Ser Asp Lys Leu Ala Arg Trp Ala Val Leu Gly Leu Gly Gly Ala Leu
        115                 120                 125

Leu Ala His Leu Val Ser Pro Leu Tyr Ser Thr Ser Leu Ile Leu Val
    130                 135                 140

Pro Pro Trp Gly Leu Pro Pro Val Ser Ala Arg Pro Pro Phe Ser Gly
145                 150                 155                 160

Pro Phe Thr Xaa Arg Pro Gly Leu Trp Gly Ser Pro Thr Ser Trp Pro
                165                 170                 175






<210> 2246
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2246
Met Phe Asp Ala Glu Ile Leu Gly Phe Ser Thr Pro Pro Gly Arg Leu
  1               5                  10                  15

Ser Met Met Ser Phe Ile Leu Asn Ala Leu Thr Cys Ala Leu Gly Leu
             20                  25                  30

Leu Tyr Phe Ile Arg Arg Gly Lys Gln Cys Leu Asp Phe Thr Val Thr
         35                  40                  45

Val His Phe Phe His Leu Leu Gly Cys Trp Phe Tyr Ser Ser Arg Phe
     50                  55                  60

Pro Ser Ala Leu Thr Trp Trp Leu Val Gln Ala Val Cys Ile Ala Leu
 65                  70                  75                  80

Met Ala Val Ile Gly Glu Tyr Leu Cys Met Arg Thr Glu Leu Lys Glu
                 85                  90                  95

Ile Pro Leu Asn Ser Ala Pro Lys Ser Asn Val 
            100                 105



<210> 2247
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2247
Met Asp Leu Gln Lys Lys Gln Ser Asn Leu Ala Thr Gly Leu Ser Lys
  1               5                  10                  15

Ala Lys Ser Gln Val Phe Lys Asn Gln Asp Pro Val Leu Pro Pro Arg
             20                  25                  30

Pro Lys Pro Gly His Pro Leu Tyr Ser Lys Tyr Met Leu Ser Val Pro
         35                  40                  45

His Gly Ile Ala Asn Glu Asp Ile Val Ser Gln Asn Pro Gly Glu Leu
     50                  55                  60

Ser Cys Lys Arg Gly Asp Val Leu Val Met Leu Lys Gln Thr Glu Asn
 65                  70                  75                  80

Asn Tyr Leu Glu Cys Gln Lys Gly Glu Asp Thr Gly Arg Val His Leu
                 85                  90                  95

Ser Gln Met Lys Ile Ile Thr Pro Leu Asp Glu His Leu Arg Ser Arg
            100                 105                 110

Pro Asn Asp Pro Ser His Ala Xaa Glu Ala Cys Xaa Thr Val Val Leu
        115                 120                 125

Leu Met Leu Ser Phe Xaa Met Ile Phe Pro Ala Glu Gln Xaa Asp Asp
    130                 135                 140






<210> 2248
<211> 127
<212> PRT
<213> Homo sapiens

<400> 2248
Met Leu Ile Leu Gly Lys Met Ile Arg Trp Glu Asp Tyr Val Leu Arg
  1               5                  10                  15

Leu Trp Arg Lys Tyr Ser Asn Lys Leu Gln Ile Leu Asn Ser Ile Phe
             20                  25                  30

Pro Gly Ile Gly Cys Pro Val Pro Arg Ile Pro Ala Glu Ala Asn Pro
         35                  40                  45

Leu Ala Asp His Val Ser Ala Thr Arg Ile Leu Cys Gly Ala Leu Val
     50                  55                  60

Phe Pro Thr Ile Ala Thr Ile Val Gly Lys Leu Met Phe Ser Ser Val
 65                  70                  75                  80

Asn Ser Asn Leu Gln Arg Thr Ile Leu Gly Gly Ile Ala Phe Val Ala
                 85                  90                  95

Ile Lys Gly Ala Phe Lys Val Tyr Phe Lys Gln Gln Gln Tyr Leu Arg
            100                 105                 110

Gln Ala His Arg Lys Ile Leu Asn Tyr Pro Glu Gln Glu Glu Ala 
        115                 120                 125



<210> 2249
<211> 112
<212> PRT
<213> Homo sapiens

<400> 2249
Met Ile Val Val Tyr Thr Glu Leu Leu Cys Met Val Ser Phe Glu Ile
  1               5                  10                  15

Ile Asp Val Arg Ile Leu Thr Phe Leu Tyr Leu Glu Thr Ser Asn Lys
             20                  25                  30

Asn Gly Lys Asn Asp His Gly Phe Lys Lys Lys Thr Lys Thr His Thr
         35                  40                  45

His Glu Leu Arg Phe Ala Asn Gln Val Ser Glu Thr Leu Gly Lys Val
     50                  55                  60

Tyr Ala Phe Asn Phe Glu Met Tyr Lys His Pro Ala Glu Thr Tyr Thr
 65                  70                  75                  80

Phe Gln Cys Ile Val His Cys Val Leu Thr Leu Gly Cys Leu Asn Leu
                 85                  90                  95

Cys Ser Asn Ile Pro Pro Pro Ser Glu Ser Leu Ser Gly Ile Pro Gln
            100                 105                 110






<210> 2250
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (65)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2250
Met Asp Arg Ile Arg His Ile Leu Ala Ala Leu His Xaa Cys Pro Lys
  1               5                  10                  15

Ile Asp Val Val Arg Val Gly Ser His Thr Ala Cys Ser Val Gly Asn
             20                  25                  30

Leu Phe Val Ile Ile Pro Ser Ala Leu Pro Glu Asn Asn Ala Ala Ser
         35                  40                  45

Val Cys Arg Pro Ile Gly Leu Met Asn Phe Ser Ala Asn Arg Phe Asn
     50                  55                  60

Xaa Pro Lys Pro Pro Arg Arg Ile Arg Ala Arg Arg Asp Ser Cys Cys
 65                  70                  75                  80

Leu Pro Val Ile Phe Ile Phe Ile Leu Xaa Val Val Phe Ile Leu Ile
                 85                  90                  95

Phe Ile Asp Pro Gly Ile Ile Ala Thr Gly Thr Ile Thr Gly Glu Gly
            100                 105                 110

Glu Asn Val 
        115



<210> 2251
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2251
Met Ile Leu Thr Tyr Tyr Glu Gly Glu Glu Val Asn Ala Gly Arg Ile
  1               5                  10                  15

Gly Leu Thr Leu Val Val Ala Gly Met Val Gly Ser Ile Leu Cys Gly
             20                  25                  30

Leu Trp Leu Asp Tyr Thr Lys Thr Tyr Asn Phe Phe Met Thr Gly Tyr
         35                  40                  45

Leu Pro Leu Gly Phe Glu Phe Ala Val Glu Ile Thr Tyr Pro Glu Ser
     50                  55                  60

Glu Gly Thr Ser Ser Gly Leu Leu Asn Ala Ser Ala Gln Ile Phe Gly
 65                  70                  75                  80

Ile Leu Phe Thr Leu Ala Gln Gly Lys Leu Thr Ser Xaa Tyr Gly Pro
                 85                  90                  95

Lys Ala Gly Asn Ile Xaa Leu Cys Val Trp Met Phe Ile Xaa Ile Ile
            100                 105                 110

Leu Thr Ala Leu Ile Lys Ser Asp Leu Arg Asp Thr Thr 
        115                 120                 125



<210> 2252
<211> 385
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2252
Met Ala Glu Asp Ala Cys Arg Ile Ser Ala His Glu Asn Ser Glu Ala
  1               5                  10                  15

Ser Phe Pro Leu Ala Val Val Ser Pro Leu Gly Lys Glu Gln Leu Pro
             20                  25                  30

Thr Thr Ser Arg Leu Met Ala Leu Glu Arg Met Gly Ile Val Ser Asp
         35                  40                  45

Tyr Glu Lys Ile Arg Thr Phe Ala Val Ala Ile Val Gly Val Gly Gly
     50                  55                  60

Val Gly Ser Val Thr Ala Glu Met Leu Thr Xaa Cys Gly Ile Gly Lys
 65                  70                  75                  80

Leu Leu Leu Phe Asp Tyr Asp Lys Val Glu Leu Ala Asn Met Asn Arg
                 85                  90                  95

Leu Phe Phe Gln Pro His Gln Ala Gly Leu Ser Lys Val Gln Ala Ala
            100                 105                 110

Glu His Thr Leu Arg Asn Ile Asn Pro Asp Val Leu Phe Glu Val His
        115                 120                 125

Asn Tyr Asn Ile Thr Thr Val Glu Asn Phe Gln His Phe Met Asp Arg
    130                 135                 140

Ile Ser Asn Gly Gly Leu Glu Glu Gly Lys Pro Val Asp Leu Val Leu
145                 150                 155                 160

Ser Cys Val Asp Asn Phe Glu Ala Arg Met Thr Ile Asn Thr Ala Cys
                165                 170                 175

Asn Glu Leu Gly Gln Thr Trp Met Glu Ser Gly Val Ser Glu Asn Ala
            180                 185                 190

Val Ser Gly His Ile Gln Leu Ile Ile Pro Gly Glu Ser Ala Cys Phe
        195                 200                 205

Ala Cys Ala Pro Pro Leu Val Val Ala Ala Asn Ile Asp Glu Lys Thr
    210                 215                 220

Leu Lys Arg Glu Gly Val Cys Ala Ala Ser Leu Pro Thr Thr Met Gly
225                 230                 235                 240

Val Val Ala Gly Ile Leu Val Gln Asn Val Leu Lys Phe Leu Leu Asn
                245                 250                 255

Phe Gly Thr Val Ser Phe Tyr Leu Gly Tyr Asn Ala Met Gln Asp Phe
            260                 265                 270

Phe Pro Thr Met Ser Met Lys Pro Asn Pro Gln Cys Asp Asp Arg Asn
        275                 280                 285

Cys Arg Lys Gln Gln Glu Glu Tyr Lys Lys Lys Val Ala Ala Leu Pro
    290                 295                 300

Lys Gln Glu Val Ile Gln Glu Glu Glu Glu Ile Ile His Glu Asp Asn
305                 310                 315                 320

Glu Trp Gly Ile Glu Leu Val Ser Glu Val Ser Glu Glu Glu Leu Lys
                325                 330                 335

Asn Phe Ser Gly Pro Val Pro Asp Leu Pro Glu Gly Ile Thr Val Ala
            340                 345                 350

Tyr Thr Ile Pro Lys Lys Gln Glu Asp Ser Val Thr Glu Leu Thr Val
        355                 360                 365

Glu Asp Ser Gly Glu Ser Leu Glu Asp Leu Met Ala Lys Met Lys Asn
    370                 375                 380

Met 
385



<210> 2253
<211> 270
<212> PRT
<213> Homo sapiens

<400> 2253
Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Asp Phe Phe
  1               5                  10                  15

Ser Ala Val Gly Lys Val Arg Asp Val Arg Ile Ile Ser Asp Arg Asn
             20                  25                  30

Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Cys Glu Ile Gln
         35                  40                  45

Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Leu Leu Gly Val
     50                  55                  60

Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Leu Ala Ala
 65                  70                  75                  80

Met Ala Asn Asn Leu Gln Lys Gly Asn Gly Gly Pro Met Arg Leu Tyr
                 85                  90                  95

Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile
            100                 105                 110

Phe Glu Pro Phe Gly Lys Ile Asp Asn Ile Val Leu Met Lys Asp Ser
        115                 120                 125

Asp Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser
    130                 135                 140

Glu Cys Ala Arg Arg Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala
145                 150                 155                 160

Gly Arg Pro Met Arg Val Gly His Val Thr Glu Arg Leu Asp Gly Gly
                165                 170                 175

Thr Asp Ile Thr Phe Pro Asp Gly Asp Gln Glu Leu Asp Leu Gly Ser
            180                 185                 190

Ala Gly Gly Arg Phe Gln Leu Met Ala Lys Leu Ala Glu Gly Ala Gly
        195                 200                 205

Ile Gln Leu Pro Ser Thr Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala
    210                 215                 220

Gln Ala Ala Ala Leu Gln Leu Asn Gly Ala Val Pro Leu Gly Ala Leu
225                 230                 235                 240

Asn Pro Ala Ala Leu Thr Ala Leu Ser Pro Ala Leu Asn Leu Ala Ser
                245                 250                 255

Gln Cys Phe Gln Leu Ser Ser Leu Phe Thr Pro Gln Thr Met 
            260                 265                 270



<210> 2254
<211> 149
<212> PRT
<213> Homo sapiens

<400> 2254
Met Ser Phe Ser Ala Tyr Gln Thr Ala Phe Ile Cys Leu Gly Leu Leu
  1               5                  10                  15

Val Gln Gln Ile Ile Phe Phe Leu Gly Thr Thr Ala Leu Ala Phe Leu
             20                  25                  30

Val Leu Met Pro Val Leu His Gly Arg Asn Leu Leu Leu Phe Arg Ser
         35                  40                  45

Leu Glu Ser Ser Trp Pro Phe Trp Leu Thr Leu Ala Leu Ala Val Ile
     50                  55                  60

Leu Gln Asn Met Ala Ala His Trp Val Phe Leu Glu Thr His Asp Gly
 65                  70                  75                  80

His Pro Gln Leu Thr Asn Arg Arg Val Leu Tyr Ala Ala Thr Phe Leu
                 85                  90                  95

Leu Phe Pro Leu Asn Val Leu Val Gly Ala Met Val Ala Thr Trp Arg
            100                 105                 110

Val Leu Leu Ser Ala Leu Tyr Asn Ala Ile His Leu Gly Gln Met Asp
        115                 120                 125

Leu Ser Leu Leu Pro Pro Arg Ala Ala Leu Ser Thr Pro Ala Thr Thr
    130                 135                 140

Arg Thr Glu Thr Ser 
145



<210> 2255
<211> 140
<212> PRT
<213> Homo sapiens

<400> 2255
Met Ala Ala Tyr Ala Met Ala Glu Ala Phe Met Ser Thr Gly Val Gly
  1               5                  10                  15

Ala Ser Leu Ile Leu Ile Ala Leu Lys Val Gly Ile Thr Ala Lys Thr
             20                  25                  30

Val Ala Val Ile Gly Ala Ile Val Thr Ser Ile Leu Ser Ile Ala Thr
         35                  40                  45

Gly Thr Ser Trp Gly Thr Phe Ala Ala Cys Ala Pro Ile Phe Leu Trp
     50                  55                  60

Leu Asn His Ile Val Gly Gly Asn Ile Leu Leu Thr Thr Ala Ala Ile
 65                  70                  75                  80

Ala Gly Gly Ala Cys Phe Gly Asp Asn Ile Gly Leu Ile Ser Asp Thr
                 85                  90                  95

Thr Ile Val Ser Ser Gly Ile Gln Lys Val Glu Val Val Arg Arg Ile
            100                 105                 110

Arg His Gln Gly Val Trp Ser Ala Leu Val Leu Leu Ser Gly Ile Ile
        115                 120                 125

Val Phe Ala Ile Val Gly Phe Thr Trp Ile Tyr Pro 
    130                 135                 140



<210> 2256
<211> 175
<212> PRT
<213> Homo sapiens

<400> 2256
Met Arg Gln Lys Lys Ile Arg Glu Asp His Lys Ser Tyr Tyr Ala Ile
  1               5                  10                  15

Asn Thr Val Tyr Val Tyr Gly Gln Glu Lys Tyr Leu Leu Leu His Asp
             20                  25                  30

Ile Ser Glu Ser Glu Phe Leu Thr Glu Ala Glu Ile Ile Cys Asp Val
         35                  40                  45

Val Cys Leu Val Tyr Asp Val Ser Asn Pro Lys Ser Phe Glu Tyr Cys
     50                  55                  60

Ala Arg Ile Phe Lys Gln His Phe Met Asp Ser Arg Ile Pro Cys Leu
 65                  70                  75                  80

Ile Val Ala Ala Lys Ser Asp Leu His Glu Val Lys Gln Glu Tyr Ser
                 85                  90                  95

Ile Ser Pro Thr Asp Phe Cys Arg Lys His Lys Met Pro Pro Pro Gln
            100                 105                 110

Ala Phe Thr Cys Asn Thr Ala Asp Ala Pro Ser Lys Asp Ile Phe Val
        115                 120                 125

Lys Leu Thr Thr Met Ala Met Tyr Pro His Val Thr Gln Ala Asp Leu
    130                 135                 140

Lys Ser Ser Thr Phe Trp Leu Arg Ala Ser Phe Gly Ala Thr Val Phe
145                 150                 155                 160

Ala Val Leu Gly Phe Ala Met Tyr Lys Ala Leu Leu Lys Gln Arg 
                165                 170                 175



<210> 2257
<211> 315
<212> PRT
<213> Homo sapiens

<400> 2257
Met Asp Phe Gly Val Leu Val Pro Thr Ala Tyr Met Phe Trp Gly Leu
  1               5                  10                  15

Leu Ser Cys Ser Leu Pro Thr Phe Cys Val Met Ser Val Pro Gly Arg
             20                  25                  30

Trp Pro Pro Ala Arg Trp Arg Leu Ser Ile Leu Ala Val Ser Ile Met
         35                  40                  45

Pro Cys Val Cys Leu Ala Ser Leu Leu Gln Ile Leu Trp Thr Arg Ser
     50                  55                  60

Ser Ser Pro Ala His His Leu Ala Ser Pro Phe Leu Cys Val Gln Ile
 65                  70                  75                  80

Trp Gln Cys Gly Gly Val Leu Glu Thr His Pro Cys Ser His Val Gly
                 85                  90                  95

His Val Phe Pro Lys Gln Ala Pro Tyr Ser Arg Asn Lys Ala Leu Ala
            100                 105                 110

Asn Ser Val Arg Ala Ala Glu Val Trp Met Asp Glu Phe Lys Glu Leu
        115                 120                 125

Tyr Tyr His Arg Asn Pro Arg Ala Arg Leu Glu Pro Phe Gly Asp Val
    130                 135                 140

Thr Glu Arg Lys Gln Leu Arg Asp Lys Leu Gln Cys Lys Asp Phe Lys
145                 150                 155                 160

Trp Phe Leu Glu Thr Val Tyr Pro Glu Leu His Val Pro Glu Asp Arg
                165                 170                 175

Pro Gly Phe Phe Gly Met Leu Gln Asn Lys Gly Leu Thr Asp Tyr Cys
            180                 185                 190

Phe Asp Tyr Asn Pro Pro Asp Glu Asn Gln Ile Val Gly His Gln Val
        195                 200                 205

Ile Leu Tyr Leu Cys His Gly Met Gly Gln Asn Gln Phe Phe Glu Tyr
    210                 215                 220

Thr Ser Gln Lys Glu Ile Arg Tyr Asn Thr His Gln Pro Glu Gly Cys
225                 230                 235                 240

Ile Ala Val Glu Ala Gly Met Asp Thr Leu Ile Met His Leu Cys Glu
                245                 250                 255

Glu Thr Ala Pro Glu Asn Gln Lys Phe Ile Leu Gln Glu Asp Gly Ser
            260                 265                 270

Leu Phe His Glu Gln Ser Lys Lys Cys Val Gln Ala Ala Arg Lys Glu
        275                 280                 285

Ser Ser Asp Ser Phe Val Pro Leu Leu Arg Asp Cys Thr Asn Ser Asp
    290                 295                 300

His Gln Lys Trp Phe Phe Lys Glu Arg Met Leu 
305                 310                 315



<210> 2258
<211> 200
<212> PRT
<213> Homo sapiens

<400> 2258
Met His Gly His Ser Asp His Gly His Gly His Ser His Gly Ser Ala
  1               5                  10                  15

Gly Gly Gly Met Asn Ala Asn Met Arg Gly Val Phe Leu His Val Leu
             20                  25                  30

Ala Asp Thr Leu Gly Ser Ile Gly Val Ile Val Ser Thr Val Leu Ile
         35                  40                  45

Glu Gln Phe Gly Trp Phe Ile Ala Asp Pro Leu Cys Ser Leu Phe Ile
     50                  55                  60

Ala Ile Leu Ile Phe Leu Ser Val Val Pro Leu Ile Lys Asp Ala Cys
 65                  70                  75                  80

Gln Val Leu Leu Leu Arg Leu Pro Pro Glu Tyr Glu Lys Glu Leu His
                 85                  90                  95

Ile Ala Leu Glu Lys Ile Gln Lys Ile Glu Gly Leu Ile Ser Tyr Arg
            100                 105                 110

Asp Pro His Phe Trp Arg His Ser Ala Ser Ile Val Ala Gly Thr Ile
        115                 120                 125

His Ile Gln Val Thr Ser Asp Val Leu Glu Gln Arg Ile Val Gln Gln
    130                 135                 140

Val Thr Gly Ile Leu Lys Asp Ala Gly Val Asn Asn Leu Thr Ile Gln
145                 150                 155                 160

Val Glu Lys Glu Ala Tyr Phe Gln His Met Ser Gly Leu Ser Thr Gly
                165                 170                 175

Phe His Asp Val Leu Ala Met Thr Lys Gln Met Glu Ser Met Lys Tyr
            180                 185                 190

Cys Lys Asp Gly Thr Tyr Ile Met 
        195                 200



<210> 2259
<211> 240
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (199)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2259
Met Pro Ser Ser Pro Ser Thr Lys Ser Asp Gly His His Gln Tyr Lys
  1               5                  10                  15

Asp Ile Pro Asn Pro Leu Ile Ala Gly Ile Ser Asn Val Leu Asn Thr
             20                  25                  30

Pro Ser Ser Ala Ala Phe Pro Thr Ala Ser Ala Gly Ser Ser Ser Val
         35                  40                  45

Lys Ser Gln Pro Gly Leu Leu Gly Met Pro Leu Asn Gln Ile Leu Asn
     50                  55                  60

Gln His Asn Ala Ala Ser Phe Pro Ala Ser Ser Leu Leu Ser Ala Ala
 65                  70                  75                  80

Ala Lys Ala Gln Leu Ala Asn Gln Asn Lys Leu Ala Gly Asn Asn Ser
                 85                  90                  95

Ser Ser Ser Ser Asn Ser Gly Ala Val Ala Gly Ser Gly Asn Thr Glu
            100                 105                 110

Gly His Ser Thr Leu Asn Thr Met Phe Pro Pro Thr Ala Asn Met Leu
        115                 120                 125

Leu Pro Thr Gly Glu Gly Gln Ser Gly Arg Ala Ala Leu Arg Asp Lys
    130                 135                 140

Leu Met Ser Gln Gln Lys Asp Ala Leu Arg Lys Arg Lys Gln Pro Pro
145                 150                 155                 160

Thr Thr Val Leu Ser Leu Leu Arg Gln Ser Gln Met Asp Ser Ser Ala
                165                 170                 175

Val Pro Lys Pro Gly Pro Asp Leu Leu Arg Lys Gln Gly Gln Gly Ser
            180                 185                 190

Phe Pro Ile Ser Ser Met Xaa Gln Leu Leu Gln Ser Met Ser Cys Gln
        195                 200                 205

Ser Ser His Leu Ser Ser Asn Ser Thr Pro Gly Cys Gly Ala Ser Asn
    210                 215                 220

Thr Ala Leu Leu Ala Leu Leu Thr Ser Cys Ile Leu Gln Ile Pro Val
225                 230                 235                 240






<210> 2260
<211> 291
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (200)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2260
Met Asp Ser Pro Trp Asp Glu Leu Ala Leu Ala Phe Ser Arg Thr Ser
  1               5                  10                  15

Met Phe Pro Phe Phe Asp Ile Ala His Tyr Leu Val Ser Val Met Ala
             20                  25                  30

Val Lys Arg Gln Pro Gly Ala Ala Ala Leu Ala Trp Lys Asn Pro Ile
         35                  40                  45

Ser Ser Trp Phe Thr Ala Met Leu His Cys Phe Gly Gly Gly Ile Leu
     50                  55                  60

Ser Cys Leu Leu Leu Ala Glu Pro Pro Leu Lys Phe Leu Ala Asn His
 65                  70                  75                  80

Thr Asn Ile Leu Leu Ala Ser Ser Ile Trp Tyr Ile Thr Phe Phe Cys
                 85                  90                  95

Pro His Asp Leu Val Ser Gln Gly Tyr Ser Tyr Leu Pro Val Gln Leu
            100                 105                 110

Leu Ala Ser Gly Met Lys Glu Val Thr Arg Thr Trp Lys Ile Val Gly
        115                 120                 125

Gly Val Thr His Ala Asn Ser Tyr Tyr Lys Asn Gly Trp Ile Val Met
    130                 135                 140

Ile Ala Ile Gly Trp Ala Arg Gly Ala Gly Gly Thr Ile Ile Thr Asn
145                 150                 155                 160

Phe Glu Arg Leu Val Lys Gly Asp Trp Lys Pro Glu Gly Asp Glu Trp
                165                 170                 175

Leu Lys Met Ser Tyr Pro Ala Lys Val Thr Leu Leu Gly Ser Val Ile
            180                 185                 190

Phe Thr Phe Gln Xaa Thr Gln Xaa Leu Ala Ile Ser Lys His Asn Leu
        195                 200                 205

Met Phe Leu Tyr Thr Ile Phe Ile Val Ala Thr Lys Ile Thr Met Met
    210                 215                 220

Thr Thr Gln Thr Ser Thr Met Thr Phe Ala Pro Phe Glu Asp Thr Leu
225                 230                 235                 240

Ser Trp Met Leu Phe Gly Trp Gln Gln Pro Phe Ser Ser Cys Glu Lys
                245                 250                 255

Lys Ser Glu Ala Lys Ser Pro Ser Asn Gly Val Gly Ser Leu Ala Ser
            260                 265                 270

Lys Pro Val Asp Val Ala Ser Asp Asn Val Lys Lys Lys His Thr Lys
        275                 280                 285

Lys Asn Glu 
    290



<210> 2261
<211> 133
<212> PRT
<213> Homo sapiens

<400> 2261
Met Gln Ser Gly Gly Gly Val Lys Thr Asp Asp Thr Ser Thr Leu Asn
  1               5                  10                  15

Ser Leu Cys Gly Tyr Ala Trp Val Tyr Val Trp Glu Glu Lys Gln Arg
             20                  25                  30

Cys Arg Leu Ser Ser Phe Phe Ser Ser Ser Ala Ser Ile Pro Gly Leu
         35                  40                  45

Leu Pro Ser His Thr Leu Asp Leu Val Gln Asn Val Gly Val Val Leu
     50                  55                  60

Asp Glu Ala Leu Gly Trp Gly Arg Glu Arg Glu Leu Cys Val Lys Cys
 65                  70                  75                  80

Leu Leu Glu Met His Cys Gly Val Phe Ser Cys Met Gly Asn His Leu
                 85                  90                  95

Cys Gln Ala Phe Pro His Phe Pro Tyr Leu Ser His Leu Val Ser Cys
            100                 105                 110

Leu Cys Phe Gln Leu Cys Val Ile Leu Phe Ala Ser Cys Thr Lys Leu
        115                 120                 125

Ile Phe Ser Lys Val 
    130



<210> 2262
<211> 259
<212> PRT
<213> Homo sapiens

<400> 2262
Met Leu Pro Ser Thr Ser Val Asn Ser Leu Val Gln Gly Asn Gly Val
  1               5                  10                  15

Leu Asn Ser Arg Asp Ala Ala Arg His Thr Ala Gly Ala Lys Arg Tyr
             20                  25                  30

Lys Tyr Leu Arg Arg Leu Phe Arg Phe Arg Gln Met Asp Phe Glu Phe
         35                  40                  45

Ala Ala Trp Gln Met Leu Tyr Leu Phe Thr Ser Pro Gln Arg Val Tyr
     50                  55                  60

Arg Asn Phe His Tyr Arg Lys Gln Thr Lys Asp Gln Trp Ala Arg Asp
 65                  70                  75                  80

Asp Pro Ala Phe Leu Val Leu Leu Ser Ile Trp Leu Cys Val Ser Thr
                 85                  90                  95

Ile Gly Phe Gly Phe Val Leu Asp Met Gly Phe Phe Glu Thr Ile Lys
            100                 105                 110

Leu Leu Leu Trp Val Val Leu Ile Asp Cys Val Gly Val Gly Leu Leu
        115                 120                 125

Ile Ala Thr Leu Met Trp Phe Ile Ser Asn Lys Tyr Leu Val Lys Arg
    130                 135                 140

Gln Ser Arg Asp Tyr Asp Val Glu Trp Gly Tyr Ala Phe Asp Val His
145                 150                 155                 160

Leu Asn Ala Phe Tyr Pro Leu Leu Val Ile Leu His Phe Ile Gln Leu
                165                 170                 175

Phe Phe Ile Asn His Val Ile Leu Thr Asp Thr Phe Ile Gly Tyr Leu
            180                 185                 190

Val Gly Asn Thr Leu Trp Leu Val Ala Val Gly Tyr Tyr Ile Tyr Val
        195                 200                 205

Thr Phe Leu Gly Tyr Ser Ala Leu Pro Phe Leu Lys Asn Thr Val Ile
    210                 215                 220

Leu Leu Tyr Pro Phe Ala Pro Leu Ile Leu Leu Tyr Gly Leu Ser Leu
225                 230                 235                 240

Ala Leu Gly Trp Asn Phe Thr His Thr Leu Cys Ser Phe Tyr Lys Tyr
                245                 250                 255

Arg Val Lys 




<210> 2263
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2263
Met Ala Gly Glu Gly Asp Gln Gln Asp Ala Ala His Asn Met Gly Asn
  1               5                  10                  15

His Leu Pro Leu Leu Pro Ala Glu Ser Glu Glu Glu Asp Glu Met Glu
             20                  25                  30

Val Glu Asp Gln Asp Ser Lys Glu Ala Lys Lys Pro Asn Ile Ile Asn
         35                  40                  45

Phe Asp Thr Ser Leu Pro Thr Ser His Thr Tyr Leu Gly Ala Asp Met
     50                  55                  60

Glu Glu Phe His Gly Arg Thr Leu His Asp Asp Asp Ser Cys Gln Val
 65                  70                  75                  80

Ile Pro Val Leu Pro Gln Val Met Met Ile Leu Ile Pro Gly Gln Thr
                 85                  90                  95

Leu Pro Leu Gln Leu Phe His Pro Gln Glu Val Ser Met Val Arg Asn
            100                 105                 110

Leu Ile Gln Lys Asp Arg Thr Phe Ala Val Leu Ala Tyr Ser Asn Val
        115                 120                 125

Gln Glu Arg Glu Ala Gln Phe Gly Thr Thr Ala Glu Ile Tyr Ala Tyr
    130                 135                 140

Arg Glu Glu Gln Asp Phe Gly Ile Glu Ile Val Lys Val Lys Ala Ile
145                 150                 155                 160

Xaa Lys Thr Lys Val Gln Ser Pro Leu Ser 
                165                 170



<210> 2264
<211> 330
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2264
Met Ile Met Met Phe Lys Ile Pro Pro Ser Asp Gly Leu Leu Ile Leu
  1               5                  10                  15

Pro Cys Tyr Gly Ser Met Thr Thr Asp Gln Gln Arg Xaa Ile Phe Leu
             20                  25                  30

Pro Pro Pro Pro Gly Ile Xaa Lys Cys Val Ile Ser Thr Asn Ile Ser
         35                  40                  45

Ala Thr Ser Leu Thr Ile Asp Gly Ile Arg Tyr Val Val Asp Gly Gly
     50                  55                  60

Phe Val Lys Gln Leu Asn His Asn Pro Arg Leu Gly Leu Asp Ile Leu
 65                  70                  75                  80

Glu Val Val Pro Ile Ser Lys Ser Glu Ala Leu Gln Arg Ser Gly Arg
                 85                  90                  95

Ala Gly Arg Thr Ser Ser Gly Lys Cys Phe Arg Ile Tyr Ser Lys Asp
            100                 105                 110

Phe Xaa Asn Gln Cys Met Pro Asp His Val Ile Pro Glu Ile Lys Arg
        115                 120                 125

Thr Ser Leu Thr Ser Val Val Leu Thr Leu Lys Cys Leu Ala Ile Xaa
    130                 135                 140

Asp Val Ile Arg Phe Pro Xaa Leu Asp Pro Pro Asn Glu Arg Leu Ile
145                 150                 155                 160

Leu Glu Ala Leu Lys Gln Leu Tyr Gln Cys Asp Ala Ile Asp Arg Ser
                165                 170                 175

Gly His Val Thr Arg Leu Gly Leu Ser Met Val Glu Phe Pro Leu Pro
            180                 185                 190

Pro His Leu Thr Cys Ala Val Ile Lys Ala Ala Ser Leu Asp Cys Glu
        195                 200                 205

Asp Leu Leu Leu Pro Ile Ala Ala Met Leu Ser Val Glu Asn Val Phe
    210                 215                 220

Ile Arg Pro Val Asp Pro Glu Tyr Gln Lys Glu Ala Glu Gln Arg His
225                 230                 235                 240

Arg Glu Leu Ala Ala Lys Ala Gly Gly Phe Asn Asp Phe Ala Thr Leu
                245                 250                 255

Ala Val Ile Phe Glu Gln Cys Lys Ser Ser Gly Ala Pro Ala Ser Trp
            260                 265                 270

Cys Gln Lys His Trp Ile His Trp Arg Cys Leu Phe Ser Ala Phe Arg
        275                 280                 285

Val Glu Ala Gln Leu Arg Glu Leu Ile Arg Lys Leu Lys Gln Gln Ser
    290                 295                 300

Asp Ser Gln Lys Arg Pro Leu Lys Ala Leu Asn Met Lys Tyr Tyr Glu
305                 310                 315                 320

Asp Val Phe Val Arg Ala Ile Ser Lys Met 
                325                 330



<210> 2265
<211> 239
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (194)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2265
Met Pro Leu Gly His Ile Met Arg Leu Asp Leu Glu Lys Ile Ala Leu
  1               5                  10                  15

Glu Tyr Ile Val Pro Cys Leu His Glu Val Gly Phe Cys Tyr Leu Asp
             20                  25                  30

Asn Phe Leu Gly Glu Val Val Gly Asp Cys Val Leu Glu Arg Val Lys
         35                  40                  45

Gln Leu His Cys Thr Gly Ala Leu Arg Asp Gly Gln Leu Ala Gly Pro
     50                  55                  60

Arg Ala Gly Val Ser Lys Arg His Leu Arg Gly Asp Gln Ile Thr Trp
 65                  70                  75                  80

Ile Gly Gly Asn Glu Glu Gly Cys Glu Ala Ile Ser Phe Leu Leu Ser
                 85                  90                  95

Leu Ile Asp Arg Leu Val Leu Tyr Cys Gly Ser Arg Leu Gly Lys Tyr
            100                 105                 110

Tyr Val Lys Glu Arg Ser Lys Ala Met Val Ala Cys Tyr Pro Gly Asn
        115                 120                 125

Gly Thr Gly Tyr Val Arg His Val Asp Asn Pro Asn Gly Asp Gly Arg
    130                 135                 140

Cys Ile Thr Cys Ile Tyr Tyr Leu Asn Lys Asn Trp Asp Ala Lys Leu
145                 150                 155                 160

His Gly Gly Ile Leu Arg Ile Phe Pro Glu Gly Lys Ser Phe Ile Ala
                165                 170                 175

Asp Val Glu Pro Ile Phe Asp Arg Leu Leu Phe Phe Trp Ser Asp Arg
            180                 185                 190

Arg Xaa Pro His Glu Val Gln Pro Ser Tyr Ala Thr Arg Tyr Ala Met
        195                 200                 205

Thr Val Trp Tyr Phe Asp Ala Glu Glu Arg Ala Glu Ala Lys Lys Lys
    210                 215                 220

Phe Arg Asn Leu Thr Arg Lys Thr Glu Ser Ala Leu Thr Glu Asp 
225                 230                 235



<210> 2266
<211> 418
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2266
Met Arg His Ala Ala Asn Met Ala Pro Val Glu His Val Val Ala Asp
  1               5                  10                  15

Ala Gly Ala Phe Leu Arg His Ala Ala Leu Gln Asp Ile Gly Lys Asn
             20                  25                  30

Ile Tyr Thr Ile Arg Glu Val Val Thr Glu Ile Arg Asp Lys Ala Thr
         35                  40                  45

Arg Arg Arg Leu Ala Val Leu Pro Tyr Glu Leu Arg Phe Lys Glu Pro
     50                  55                  60

Leu Pro Glu Tyr Val Arg Leu Val Thr Glu Phe Ser Lys Lys Thr Gly
 65                  70                  75                  80

Asp Tyr Pro Ser Leu Ser Ala Thr Asp Ile Gln Val Leu Ala Leu Thr
                 85                  90                  95

Tyr Gln Leu Glu Ala Glu Phe Val Gly Val Ser His Leu Lys Gln Glu
            100                 105                 110

Pro Gln Lys Val Lys Val Ser Ser Ser Ile Gln His Pro Glu Thr Pro
        115                 120                 125

Leu His Ile Ser Gly Phe His Leu Pro Tyr Lys Pro Lys Pro Pro Gln
    130                 135                 140

Glu Thr Glu Lys Gly His Ser Ala Cys Glu Pro Glu Asn Leu Glu Phe
145                 150                 155                 160

Ser Ser Phe Met Phe Trp Arg Asn Pro Leu Pro Asn Ile Asp His Glu
                165                 170                 175

Leu Gln Glu Leu Leu Ile Asp Arg Gly Glu Asp Val Pro Ser Glu Glu
            180                 185                 190

Glu Glu Glu Glu Glu Asn Gly Phe Glu Asp Arg Lys Asp Asp Ser Asp
        195                 200                 205

Asp Asp Gly Gly Gly Trp Ile Thr Pro Ser Asn Ile Lys Gln Ile Gln
    210                 215                 220

Gln Glu Leu Glu Gln Cys Asp Val Pro Glu Asp Val Xaa Val Gly Cys
225                 230                 235                 240

Leu Thr Thr Asp Phe Ala Met Gln Asn Val Leu Leu Gln Met Gly Leu
                245                 250                 255

His Val Leu Ala Val Asn Gly Met Leu Ile Arg Glu Ala Arg Ser Tyr
            260                 265                 270

Ile Leu Arg Cys His Gly Cys Phe Lys Thr Thr Ser Asp Met Ser Arg
        275                 280                 285

Val Phe Cys Ser His Cys Gly Asn Lys Thr Leu Lys Lys Val Ser Val
    290                 295                 300

Thr Val Ser Asp Asp Gly Thr Leu His Met His Phe Ser Arg Asn Pro
305                 310                 315                 320

Lys Val Leu Asn Pro Arg Gly Leu Arg Tyr Ser Leu Pro Thr Pro Lys
                325                 330                 335

Gly Gly Lys Tyr Ala Ile Asn Pro His Leu Thr Glu Asp Gln Arg Phe
            340                 345                 350

Pro Gln Leu Arg Leu Ser Gln Lys Ala Arg Gln Lys Thr Asn Val Phe
        355                 360                 365

Ala Pro Asp Tyr Ile Ala Gly Val Ser Pro Phe Val Glu Asn Asp Ile
    370                 375                 380

Ser Ser Arg Ser Ala Thr Leu Gln Val Arg Asp Ser Thr Leu Gly Ala
385                 390                 395                 400

Gly Arg Arg Arg Leu Asn Pro Asn Ala Ser Arg Lys Lys Phe Val Lys
                405                 410                 415

Lys Arg 




<210> 2267
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2267
Met Val Ser Val Gly Gly Asp Val Xaa Leu Gly Val Arg Arg Pro His
  1               5                  10                  15

Gly Pro Glu Ala Gly Pro Gly Pro Pro Arg Val Ala Val Leu Leu Pro
             20                  25                  30

Val Gly Gly Cys Gly Leu Cys Cys His Pro Arg Val Cys Thr Pro Phe
         35                  40                  45

Phe Arg Ser Leu Trp Thr Ser Val Val Leu Tyr Phe Gly Ala Ser Gly
     50                  55                  60

Glu Val Phe Asn Phe Leu Val Ile Asp Asp Cys Gln Val Leu Lys Tyr
 65                  70                  75                  80

Gln Ser Phe Phe Val Leu Phe Leu Asn Lys Tyr Leu Ser Asn Phe Gln
                 85                  90                  95

Lys Lys Lys Lys Lys Lys Lys Lys Lys 
            100                 105



<210> 2268
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (4)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2268
Met Lys Asp Xaa Ala Leu Lys Xaa Lys Val Ser Thr Ala Thr Val Ser
  1               5                  10                  15

Arg Ala Leu Met Asn Pro Asp Lys Val Ser Gln Ala Thr Arg Asn Arg
             20                  25                  30

Val Glu Lys Ala Ala Arg Glu Val Gly Tyr Leu Pro Gln Pro Met Gly
         35                  40                  45

Arg Asn Val Lys Arg Asn Glu Ser Arg Thr Ile Leu Val Ile Val Pro
     50                  55                  60

Asp Ile Cys Asp Pro Phe Phe Ser Glu Ile Ile Arg Gly Ile Glu Val
 65                  70                  75                  80

Thr Ala Ala Asn His Gly Tyr Leu Val Xaa Ile Gly Asp Cys Ala His
                 85                  90                  95

Gln Asn Gln Gln Glu Lys Thr Phe Ile Xaa Leu Ile Ile Thr Lys Gln
            100                 105                 110

Ile Asp Trp 
        115



<210> 2269
<211> 253
<212> PRT
<213> Homo sapiens

<400> 2269
Met Thr Pro Ser Ala Ala Thr Pro Ala Pro Ala Ser Gly Ile Gly Cys
  1               5                  10                  15

Gly Asn Pro Arg Gly Trp Ala Trp Gln Gly Gly Thr Cys Ser Pro Asp
             20                  25                  30

Ala Leu Thr Pro Pro Arg Arg Phe Phe Tyr Leu Tyr His Phe Ala Phe
         35                  40                  45

Tyr Ala Tyr His Tyr Arg Phe Asn Gly Gln Tyr Ser Ser Leu Ala Leu
     50                  55                  60

Val Thr Ser Trp Leu Phe Ile Gln His Ser Met Ile Tyr Phe Phe His
 65                  70                  75                  80

His Tyr Glu Leu Pro Ala Ile Leu Gln Gln Val Arg Ile Gln Glu Met
                 85                  90                  95

Leu Leu Gln Ala Pro Pro Leu Gly Pro Gly Thr Pro Thr Ala Leu Pro
            100                 105                 110

Asp Asp Met Asn Asn Asn Ser Gly Ala Pro Ala Thr Ala Pro Asp Ser
        115                 120                 125

Ala Gly Gln Pro Pro Ala Leu Gly Pro Val Ser Pro Gly Ala Ser Gly
    130                 135                 140

Ser Pro Gly Pro Val Ala Ala Ala Pro Ser Ser Leu Val Ala Ala Ala
145                 150                 155                 160

Ala Ser Val Ala Ala Ala Ala Gly Gly Asp Leu Gly Trp Met Ala Glu
                165                 170                 175

Thr Ala Ala Ile Ile Thr Asp Ala Ser Phe Leu Ser Gly Leu Ser Ala
            180                 185                 190

Ser Leu Leu Glu Arg Arg Pro Ala Ser Pro Leu Gly Pro Ala Gly Gly
        195                 200                 205

Leu Pro His Ala Pro Gln Asp Ser Val Pro Pro Ser Asp Ser Ala Ala
    210                 215                 220

Ser Asp Thr Thr Pro Leu Gly Ala Ala Val Gly Gly Pro Ser Pro Ala
225                 230                 235                 240

Ser Met Ala Pro Thr Glu Ala Pro Ser Glu Val Gly Ser 
                245                 250



<210> 2270
<211> 441
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2270
Met Leu Thr Val Leu His Glu Thr Phe Ser Gln His Thr Phe Leu Met
  1               5                  10                  15

Asn Gly Leu Ile Gln Gly Val Lys Gly Leu Leu Ser Phe Leu Ser Ala
             20                  25                  30

Pro Leu Ile Gly Ala Leu Ser Asp Val Trp Gly Arg Lys Pro Phe Leu
         35                  40                  45

Leu Gly Thr Val Phe Phe Thr Cys Phe Pro Ile Pro Leu Met Arg Ile
     50                  55                  60

Ser Pro Trp Trp Tyr Phe Ala Met Ile Ser Val Ser Gly Val Phe Ser
 65                  70                  75                  80

Val Thr Phe Ser Val Ile Phe Ala Tyr Val Ala Asp Val Thr Gln Glu
                 85                  90                  95

His Glu Arg Ser Thr Ala Tyr Gly Trp Val Ser Ala Thr Phe Xaa Ala
            100                 105                 110

Ser Leu Val Ser Ser Pro Ala Ile Gly Ala Tyr Leu Ser Ala Ser Tyr
        115                 120                 125

Gly Asp Ser Leu Val Val Leu Val Ala Thr Val Val Ala Leu Leu Asp
    130                 135                 140

Ile Cys Phe Ile Leu Val Ala Val Pro Glu Ser Leu Pro Glu Lys Met
145                 150                 155                 160

Arg Pro Val Ser Trp Gly Ala Gln Ile Ser Trp Lys Gln Ala Asp Pro
                165                 170                 175

Phe Ala Ser Leu Lys Lys Val Gly Lys Asp Ser Thr Val Leu Leu Ile
            180                 185                 190

Cys Ile Thr Val Phe Leu Ser Tyr Leu Pro Glu Ala Gly Gln Tyr Ser
        195                 200                 205

Ser Phe Phe Leu Tyr Leu Arg Gln Val Ile Gly Phe Gly Ser Val Lys
    210                 215                 220

Ile Ala Ala Phe Ile Ala Met Val Gly Ile Leu Ser Ile Val Ala Gln
225                 230                 235                 240

Thr Ala Phe Leu Ser Ile Leu Met Arg Ser Leu Gly Asn Lys Asn Thr
                245                 250                 255

Val Leu Leu Gly Leu Gly Phe Gln Met Leu Gln Leu Ala Trp Tyr Gly
            260                 265                 270

Phe Gly Ser Gln Ala Trp Met Met Trp Ala Ala Gly Thr Val Ala Ala
        275                 280                 285

Met Ser Ser Ile Thr Phe Pro Ala Ile Ser Ala Leu Val Ser Arg Asn
    290                 295                 300

Ala Glu Ser Asp Gln Gln Gly Val Ala Gln Gly Ile Ile Thr Gly Ile
305                 310                 315                 320

Arg Gly Leu Cys Asn Gly Leu Gly Pro Ala Leu Tyr Gly Phe Ile Phe
                325                 330                 335

Tyr Met Phe His Val Glu Leu Thr Glu Leu Gly Pro Lys Leu Asn Ser
            340                 345                 350

Asn Asn Val Pro Leu Gln Gly Ala Val Ile Pro Gly Pro Pro Phe Leu
        355                 360                 365

Phe Gly Ala Cys Ile Val Leu Met Ser Phe Leu Val Ala Leu Phe Ile
    370                 375                 380

Pro Glu Tyr Ser Lys Ala Ser Gly Val Gln Lys His Ser Asn Ser Ser
385                 390                 395                 400

Ser Gly Ser Leu Thr Asn Thr Pro Glu Arg Gly Ser Asp Glu Asp Ile
                405                 410                 415

Glu Pro Leu Leu Gln Asp Ser Ser Ile Trp Glu Leu Ser Ser Phe Glu
            420                 425                 430

Glu Pro Gly Asn Gln Cys Thr Glu Leu 
        435                 440



<210> 2271
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2271
Met Ser Arg Gln Lys Glu Thr Leu Gln Ser Ala Phe Pro Ser Met Cys
  1               5                  10                  15

Ala Leu Cys Pro Ser Glu Pro Ala Asp Xaa Arg Gly Gly Lys Asp Thr
             20                  25                  30

Val Leu Asn Glu Gln Asn Leu Gln Asp Thr Gln Ser Cys Leu Phe Ala
         35                  40                  45

Thr Trp Pro Tyr Ala Cys Pro Val Phe Ser Leu Lys Ala Phe Thr His
     50                  55                  60

Ala Arg Ala Val Thr Trp Asn Val Leu Ser Ile Thr Pro Ala Val Met
 65                  70                  75                  80

Pro Ser Thr Glu Leu Asp Gly Arg Pro Leu His Gly Ser Leu Lys Arg
                 85                  90                  95

Ser His Pro Ser Asn Trp Val Cys His Arg His Thr Gly Ser Cys Leu
            100                 105                 110

Pro Val Leu Pro Val Val Ile Val Met Arg Ile Val Val Leu His Pro
        115                 120                 125






<210> 2272
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2272
Met Gly Ser Arg Leu Ser Gln Pro Phe Glu Ser Tyr Ile Thr Ala Pro
  1               5                  10                  15

Pro Gly Thr Ala Ala Ala Pro Ala Lys Pro Ala Xaa Pro Ala Thr Pro
             20                  25                  30

Gly Ala Pro Thr Ser Pro Ala Glu His Arg Leu Leu Lys Thr Cys Trp
         35                  40                  45

Ser Cys Arg Val Leu Ser Gly Leu Gly Leu Met Gly Ala Gly Gly Tyr
     50                  55                  60

Val Tyr Trp Val Ala Arg Lys Pro Met Lys Met Gly Tyr Pro Pro Ser
 65                  70                  75                  80

Pro Trp Thr Ile Thr Gln Met Val Ile Gly Leu Ser Ile Ala Thr Trp
                 85                  90                  95

Gly Ile Val Val Met Ala Asp Pro Lys Gly Lys Ala Tyr Arg Val Val
            100                 105                 110






<210> 2273
<211> 157
<212> PRT
<213> Homo sapiens

<400> 2273
Met Lys Leu Leu Pro Val Asp Cys Glu Arg Lys Thr Asp Glu Phe Cys
  1               5                  10                  15

Gln Ala Lys Gln Lys Ala Ala Leu Leu Glu Leu Leu His Glu Leu Tyr
             20                  25                  30

Asn Phe Leu Ala Ile Gln Ala Gly Asn Phe Glu Cys Gly Asn Pro Glu
         35                  40                  45

Asn Leu Lys Ser Lys Cys Ile Pro Val Met Glu Ala Gln Glu Tyr Ile
     50                  55                  60

Ala Asn Val Thr Ser Ser Ser Ser Ala Lys Phe Glu Ala Ala Leu Thr
 65                  70                  75                  80

Trp Ile Leu Ser Ser Asn Lys Asp Val Gly Ile Trp Leu Lys Gly Glu
                 85                  90                  95

Asp Gln Ser Glu Leu Val Thr Thr Val Asp Lys Val Val Cys Leu Glu
            100                 105                 110

Ser Ala His Pro Arg Met Gly Val Gly Cys Arg Leu Ser Arg Ala Leu
        115                 120                 125

Leu Thr Ala Val Thr Asn Val Leu Ile Phe Phe Trp Cys Leu Ala Phe
    130                 135                 140

Leu Trp Gly Leu Leu Ile Leu Leu Lys Tyr Arg Trp Arg 
145                 150                 155



<210> 2274
<211> 309
<212> PRT
<213> Homo sapiens

<400> 2274
Met Pro Glu His Arg Leu Ser His Gln Thr Val Leu Met Thr Arg Pro
  1               5                  10                  15

Arg Cys Ala Pro Lys Val Leu Cys Ala Val Gly Gly Lys Ser Gly Leu
             20                  25                  30

Phe Ala Cys Leu Asp Ser Val Glu Met Tyr Phe Pro Gln Asn Asp Ser
         35                  40                  45

Trp Ile Gly Leu Ala Pro Leu Asn Ile Pro Arg Tyr Glu Phe Gly Ile
     50                  55                  60

Cys Val Leu Asp Gln Lys Val Tyr Val Ile Gly Gly Ile Ala Thr Asn
 65                  70                  75                  80

Val Arg Pro Gly Val Thr Ile Arg Lys His Glu Asn Ser Val Glu Cys
                 85                  90                  95

Trp Asn Pro Asp Thr Asn Thr Trp Thr Ser Leu Glu Arg Met Asn Glu
            100                 105                 110

Ser Arg Ser Thr Leu Gly Val Val Val Leu Ala Gly Glu Leu Tyr Ala
        115                 120                 125

Leu Gly Gly Tyr Asp Gly Gln Ser Tyr Leu Gln Ser Val Glu Lys Tyr
    130                 135                 140

Ile Pro Lys Ile Arg Lys Trp Gln Pro Val Ala Pro Met Thr Thr Thr
145                 150                 155                 160

Arg Ser Cys Phe Ala Ala Ala Val Leu Asp Gly Met Ile Tyr Ala Ile
                165                 170                 175

Gly Gly Tyr Gly Pro Ala His Met Asn Ser Val Glu Arg Tyr Asp Pro
            180                 185                 190

Ser Lys Asp Ser Trp Glu Met Val Ala Ser Met Ala Asp Lys Arg Ile
        195                 200                 205

His Phe Gly Val Gly Val Met Leu Gly Phe Ile Phe Val Val Gly Gly
    210                 215                 220

His Asn Gly Val Ser His Leu Ser Ser Ile Glu Arg Tyr Asp Pro His
225                 230                 235                 240

Gln Asn Gln Trp Thr Val Cys Arg Pro Met Lys Glu Pro Arg Thr Gly
                245                 250                 255

Val Gly Ala Ala Val Ile Asp Asn Tyr Leu Tyr Val Val Gly Gly His
            260                 265                 270

Ser Gly Ser Ser Tyr Leu Asn Thr Val Gln Lys Tyr Asp Pro Ile Ser
        275                 280                 285

Asp Thr Trp Leu Asp Ser Ala Gly Met Ile Tyr Cys Arg Cys Asn Phe
    290                 295                 300

Gly Leu Thr Ala Leu 
305



<210> 2275
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2275
Met Ile Pro Tyr Pro Leu Glu Lys Gly His Leu Phe Tyr Pro Tyr Pro
  1               5                  10                  15

Ile Cys Thr Glu Thr Ala Asp Arg Glu Leu Leu Pro Ser Phe His Glu
             20                  25                  30

Val Ser Val Tyr Pro Lys Lys Glu Leu Pro Phe Phe Ile Leu Phe Thr
         35                  40                  45

Ala Gly Leu Cys Ser Phe Thr Ala Met Leu Ala Leu Leu Thr His Gln
     50                  55                  60

Phe Pro Glu Leu Met Gly Val Phe Ala Lys Ala Met Ile Asp Ile Phe
 65                  70                  75                  80

Cys Ser Ala Glu Phe Arg Asp Trp Asn Cys Lys Ser Ile Phe Met Arg
                 85                  90                  95

Val Glu Asp Glu Leu Glu Ile Pro Pro Ala Pro Gln Ser Gln His Phe
            100                 105                 110

Gln Asn 




<210> 2276
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2276
Met Ser Gly Trp Ser Leu Ser His Ser Pro Leu Ile Gly Gln Trp Pro
  1               5                  10                  15

Val Thr Asp Asn Trp Leu Gly Ser Cys Leu His Ala Pro Glu Gly Leu
             20                  25                  30

Leu Gly Gly Cys His Thr Val Trp Leu Leu Ser Gly Asp Arg Leu Leu
         35                  40                  45

Val Asn Gly Val Leu Cys Leu Thr Ser Leu Ile Pro Ala Leu Pro Thr
     50                  55                  60

His Arg Arg Ala Cys Cys Pro His Xaa Pro Cys Pro Arg His Pro Leu
 65                  70                  75                  80

His Pro His Leu Leu Pro Ser Trp Ala Ala Gly Ala Tyr Ala Leu Ser
                 85                  90                  95

Thr Phe Leu Leu Leu Ile Pro Thr Val Arg Glu Thr Leu Met Trp Thr
            100                 105                 110

Arg Ser Trp Arg Thr Val Leu Thr Gly Ser Ser Pro Gly Cys Gln Lys
        115                 120                 125

Thr Arg Asp Leu Pro Arg Gln Leu Leu Met Met Ala Ala 
    130                 135                 140



<210> 2277
<211> 131
<212> PRT
<213> Homo sapiens

<400> 2277
Met Gly Gly Gly Gly Trp Glu Arg Leu His Ser Thr Pro Trp Lys Trp
  1               5                  10                  15

Glu Tyr Pro Tyr Val Val Phe Gly Ile Phe Leu Tyr Gly Lys Phe Val
             20                  25                  30

Ser Pro Ser His Pro Asn Leu Phe Thr Ser Val Trp Thr His Val Tyr
         35                  40                  45

Phe Val Phe Trp Val Thr Gln Tyr Leu Phe Cys Cys Leu Ser Cys Pro
     50                  55                  60

Ala Trp Leu Leu Gly Val Leu Pro Gly Trp Leu Leu Cys Pro Phe Asp
 65                  70                  75                  80

Val Pro Ile Leu Leu Ile Phe Glu His Phe Leu Leu Ser Gly Thr Thr
                 85                  90                  95

Arg Cys Ser Arg Phe Ile Leu Asp Ile Pro Cys Pro Asn Pro Arg Ile
            100                 105                 110

Pro Arg Ile Asn Pro Cys Ser Lys Glu Pro Trp Phe Leu Leu Leu Glu
        115                 120                 125

Asn His Thr 
    130



<210> 2278
<211> 110
<212> PRT
<213> Homo sapiens

<400> 2278
Met Pro Phe Leu Gln Asp Phe Phe Val Ile Ser Val His Met Lys Met
  1               5                  10                  15

Leu Thr Leu Asn Ile Asn Thr Trp Arg Pro Cys Pro Val Ala Leu Pro
             20                  25                  30

Trp Leu Pro Ala Trp Ser Val Phe Pro Cys Gly Phe Thr Cys Gly Pro
         35                  40                  45

Ala Val Ala Thr Ser Met Val Cys Val Leu Val Asp Ser Leu Gln Leu
     50                  55                  60

Ser Asp Ala Ser Phe Cys His Asn His Leu Phe Pro Asp Thr Ile Val
 65                  70                  75                  80

Leu Ile Leu Phe Gln Asn Cys Lys Ile Ile Ser Ser Leu Lys Cys Lys
                 85                  90                  95

Gly Cys Phe Cys Ser Val Ser Val Phe Phe Glu Ile Lys Leu 
            100                 105                 110



<210> 2279
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (12)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2279
Met Glu Trp Ile Val Leu Thr His Thr Leu Arg Xaa Arg Ala Arg Pro
  1               5                  10                  15

Glu Glu Arg Cys Cys Cys Gly Gly Ile Phe Pro Arg Gly Ser Leu Pro
             20                  25                  30

Val Leu Leu Gly Asp Gly Cys Trp Val Pro Trp Ala Thr Gly Glu Ser
         35                  40                  45

Val Arg Gly Trp Arg Arg Trp Pro Phe Leu Gly Cys Phe Leu Gly Asn
     50                  55                  60

Glu Leu Tyr Ile Ser Trp Leu Asp Phe Val Lys Ser Val Phe Lys Ile
 65                  70                  75                  80

Pro His Ile Ser Val Phe Leu Leu Glu His Leu Phe Leu Gly Leu Leu
                 85                  90                  95

Cys Thr Ala Gln Val Trp Gly Val Leu Val Ile Asp Cys Phe Arg Ser
            100                 105                 110

Arg Cys Val Trp Gly Thr Ala Leu Ala Ala Ser Glu Val Cys Val Gly
        115                 120                 125






<210> 2280
<211> 105
<212> PRT
<213> Homo sapiens

<400> 2280
Met Ala Val Ser Ser Gln Gln Gly Glu Ile Met Glu Ser Arg Ile Phe
  1               5                  10                  15

Phe Gln Gly Ser His Ala His Phe Pro Thr Cys Met Asn Val Asp Thr
             20                  25                  30

Ala Ala Thr Val Leu Ala Val Asn Val Asn Leu Ala Ser Asn His Cys
         35                  40                  45

Ser Gln Gly Asn Val Pro Ile Arg Arg Arg Leu Ser Gly Thr Leu Ile
     50                  55                  60

Leu Thr Gly Arg Trp Asp Ile Leu Arg Asp Pro Glu Ala Gly Cys His
 65                  70                  75                  80

Leu Leu Asn Phe Pro Glu Gly Cys Leu Gly Ile Cys Phe Leu Phe Ile
                 85                  90                  95

Leu Glu Leu Phe Phe Leu Phe Met Gly 
            100                 105



<210> 2281
<211> 285
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2281
Met Ala Pro Lys Pro Gly Ala Glu Trp Ser Thr Ala Leu Ser His Leu
  1               5                  10                  15

Val Leu Gly Val Val Ser Leu His Ala Ala Val Ser Thr Ala Glu Ala
             20                  25                  30

Ser Arg Gly Ala Ala Ala Gly Phe Leu Leu Gln Val Leu Ala Ala Thr
         35                  40                  45

Thr Thr Leu Ala Pro Gly Leu Ser Thr His Glu Asp Cys Leu Ala Gly
     50                  55                  60

Ala Trp Val Ala Thr Val Ile Gly Leu Pro Leu Leu Ala Phe Asp Phe
 65                  70                  75                  80

His Trp Val Asn Gly Asp Arg Ser Ser Ala Asn Leu Leu Leu Gly Gly
                 85                  90                  95

Gly Met Val Leu Ala Val Ala Gly Gly His Leu Gly Pro Glu Ala Xaa
            100                 105                 110

Cys Gly Trp Ser Gly Asn Ala Val Gly Gly Arg Ser Asp His Pro His
        115                 120                 125

Cys Ser Cys Leu His Gly Gln His Leu Trp Asp Val Gly Gly Gly Asp
    130                 135                 140

Ala Gly Cys Gly Arg Pro Pro Glu Pro Ala Gly Gly Gly Gln Ala Ala
145                 150                 155                 160

Ala Ala Thr Glu Gly Gly Cys Leu Ser Leu Gly Leu Gly Cys Arg Gln
                165                 170                 175

Leu Gly Leu Leu Pro Gly Pro Ala Tyr Thr Ala Pro Pro Val Gly Val
            180                 185                 190

Thr Val Gly Tyr Ser Gln Ala Gly Phe Leu Pro Cys Arg Thr Leu Ser
        195                 200                 205

Leu Pro Pro Ala Cys Ser Trp Arg Leu Leu Pro Arg Gly Arg Leu Phe
    210                 215                 220

Cys Leu Leu Lys Trp Val Cys Cys Thr Leu Thr Gly Gln Gly Gln Ser
225                 230                 235                 240

Leu Gly Ala Val Leu Trp Pro Arg Val Gly Thr Cys Leu Asp Gln Asn
                245                 250                 255

Glu Arg Asp Arg Val Pro Asp Thr Phe Gly Gly Pro Asp Ser Gly Leu
            260                 265                 270

Asp Thr Val Val Asp Pro Glu Lys Arg Pro Ser Leu Gln 
        275                 280                 285



<210> 2282
<211> 217
<212> PRT
<213> Homo sapiens

<400> 2282
Met Glu Asn Leu Phe Glu Lys Asn Lys Ile Arg Ala Ser Ile Ser Tyr
  1               5                  10                  15

Lys Trp Thr Pro Glu Gly Arg Arg Leu Val Thr Gly Ala Ser Ser Gly
             20                  25                  30

Glu Phe Thr Leu Trp Asn Gly Leu Thr Phe Asn Phe Glu Thr Ile Leu
         35                  40                  45

Gln Ala His Asp Ser Pro Val Arg Ala Met Thr Trp Ser His Asn Asp
     50                  55                  60

Met Trp Met Leu Thr Ala Asp His Gly Gly Tyr Val Lys Tyr Trp Gln
 65                  70                  75                  80

Ser Asn Met Asn Asn Val Lys Met Phe Gln Ala His Lys Glu Ala Ile
                 85                  90                  95

Arg Glu Ala Arg Phe Ile His Asn Ile Pro Phe Ser Val Val Pro Ile
            100                 105                 110

Val Met Val Lys Leu Phe Ser Lys Cys Ile Leu Gly Ala Glu Met His
        115                 120                 125

Gly Leu Cys Gln Phe Leu Gly Asn Phe Leu His Pro Ile Asn Thr Ile
    130                 135                 140

Phe Phe Phe Val Phe Thr His Ser Pro Phe Cys Trp His Leu Ser Glu
145                 150                 155                 160

Val Val Leu Ser Arg Tyr Gln Pro Leu Gln Tyr Val Arg Asp Val Leu
                165                 170                 175

Ser Ala Ala Phe Cys Thr Gly Phe Leu Phe Ser Phe Met Ile Asn Asn
            180                 185                 190

Val Tyr Thr Leu Phe Leu Phe Ile Ile Tyr Cys Val Arg Gln Glu Tyr
        195                 200                 205

Phe Ile Pro Asn Lys Glu Phe Ser Leu 
    210                 215



<210> 2283
<211> 169
<212> PRT
<213> Homo sapiens

<400> 2283
Met Asp Trp Gln Ser Ile Lys Ile Gln Glu Leu Met Ser Asp Asp Gln
  1               5                  10                  15

Arg Glu Ala Gly Arg Ile Pro Arg Thr Ile Glu Cys Glu Leu Val His
             20                  25                  30

Asp Leu Val Asp Ser Cys Val Pro Gly Asp Thr Val Thr Ile Thr Gly
         35                  40                  45

Ile Val Lys Val Ser Asn Ala Glu Glu Gly Ser Arg Asn Lys Asn Asp
     50                  55                  60

Lys Cys Met Phe Leu Leu Tyr Ile Glu Ala Asn Ser Ile Ser Asn Ser
 65                  70                  75                  80

Lys Gly Gln Lys Thr Lys Ser Ser Glu Asp Gly Cys Lys His Gly Met
                 85                  90                  95

Leu Met Glu Phe Ser Leu Lys Asp Leu Tyr Ala Ile Gln Glu Ile Gln
            100                 105                 110

Ala Glu Glu Asn Leu Phe Lys Leu Ile Val Asn Ser Leu Cys Pro Val
        115                 120                 125

Ile Phe Gly His Glu Leu Val Lys Ala Gly Leu Ala Leu Ala Leu Phe
    130                 135                 140

Gly Gly Ser Gln Lys Tyr Ala Asp Asp Lys Asn Arg Ile Pro Ile Arg
145                 150                 155                 160

Gly Asp Pro His Ile Leu Val Gly Phe 
                165



<210> 2284
<211> 118
<212> PRT
<213> Homo sapiens

<400> 2284
Met Gln Lys Phe Leu Gly Ser Phe Phe Ile Gly Trp Asp Leu Asp Leu
  1               5                  10                  15

Tyr His Glu Glu Ser Asp Gln Lys Ala Gln Val Asn Thr Ser Asp Leu
             20                  25                  30

Asn Glu Glu Leu Gly Gln Val Glu Tyr Val Phe Thr Asp Lys Thr Gly
         35                  40                  45

Thr Leu Thr Glu Asn Glu Met Gln Phe Arg Glu Cys Ser Ile Asn Gly
     50                  55                  60

Met Lys Tyr Gln Glu Ile Asn Gly Arg Leu Val Pro Glu Asp Gln His
 65                  70                  75                  80

Gln Thr Leu Gln Lys Glu Thr Tyr Leu Ile Leu Val Val Tyr Pro Ile
                 85                  90                  95

Leu Thr Thr Tyr Pro Ile Leu Gln Pro Val Pro Leu Ser Glu Pro Val
            100                 105                 110

Leu Lys Met Lys Leu Asn 
        115



<210> 2285
<211> 172
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2285
Met Phe Ile Leu Ser Leu Ser Phe Leu Thr Val Phe Ile Phe Ala Phe
  1               5                  10                  15

Val Ile Thr His Val Ile Leu Arg Ser Gln Gln Thr Gly Phe Leu Asn
             20                  25                  30

Ala Leu Lys Asp Ser Pro Ala Ser Val Leu Glu Ala Val Val Cys Phe
         35                  40                  45

Phe Ser Val Trp Ser Ile Val Gly Leu Ser Gly Phe His Thr Tyr Leu
     50                  55                  60

Ile Ser Ser Asn Gln Thr Thr Asn Glu Asp Ile Lys Gly Ser Trp Ser
 65                  70                  75                  80

Asn Lys Arg Gly Lys Glu Asn Tyr Asn Pro Tyr Ser Tyr Gly Asn Ile
                 85                  90                  95

Leu Pro Thr Ala Val Leu Pro Val Trp Ala His Leu Thr Lys Pro Asp
            100                 105                 110

Arg Gln Lys Arg Val His Pro Ala Arg His Ala Ala Ala Ser Ser Thr
        115                 120                 125

Leu Gln Xaa His His His Val Arg Gly His Ala Ser Gln Met Thr Trp
    130                 135                 140

Val Gln His Ala Pro Val Gln Ser Glu Pro Ser Phe Thr Ser Xaa Glu
145                 150                 155                 160

Leu His Leu Pro Gly Glu Xaa Trp Ala Trp Gly Lys 
                165                 170



<210> 2286
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2286
Met Ser Thr Trp Phe Leu Leu Val Ser Thr Phe Ser Met Leu Pro Leu
  1               5                  10                  15

Leu Xaa Lys Asp Glu Leu Leu Met Pro Ser Val Val Thr Thr Met Ala
             20                  25                  30

Phe Phe Ile Ala Cys Val Thr Ser Phe Ser Ile Phe Glu Lys Thr Ser
         35                  40                  45

Glu Glu Glu Leu Gln Leu Lys Ser Phe Ser Ile Ser Val Arg Lys Tyr
     50                  55                  60

Leu Pro Cys Phe Thr Phe Leu Ser Arg Ile Ile Gln Tyr Leu Phe Leu
 65                  70                  75                  80

Ile Ser Val Ile Thr Met Val Leu Leu Thr Leu Met Thr Val Thr Leu
                 85                  90                  95

Asp Pro Pro Gln Lys Leu Pro Asp Leu Phe Ser Val Leu Val Cys Phe
            100                 105                 110

Val Ser Cys Leu Asn Phe Leu Phe Phe Leu Val Tyr Phe Asn Ile Ile
        115                 120                 125

Ile Met Trp Asp Ser Lys Ser Gly Arg Asn Gln Lys Lys Ile Ser 
    130                 135                 140



<210> 2287
<211> 268
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (229)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (234)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (245)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (252)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (258)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (264)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2287
Met Leu Leu Lys Ile Lys Ala Val Arg Ala Ala Lys Phe Trp Lys Ile
  1               5                  10                  15

Cys Pro Met Glu His Ile Leu Val Arg Leu Glu Thr Asp Ser Arg Pro
             20                  25                  30

Val Ser Arg Arg Leu Val Ser Leu Ile Phe Asn Ser Phe Leu Pro Val
         35                  40                  45

Asn Gln Pro Glu Glu Val Trp Cys Glu Arg Cys Val Thr Leu Val Gln
     50                  55                  60

Met Asn His Ala Ala Ala Arg Arg Phe Tyr Gln Tyr Ala His Glu His
 65                  70                  75                  80

Thr Ala Cys Thr Asn Ile Ala Lys Leu Ile His Val Ile Arg His Cys
                 85                  90                  95

Leu Asn Ala Cys Ile Gln Arg Ala Val Arg Glu Pro Pro Glu Asp Glu
            100                 105                 110

Glu Glu Glu Asp Gly Arg Glu Lys Glu Asn Val Thr Val Leu Asp Lys
        115                 120                 125

Thr Leu Ser Val Asn Asp Val Ala Cys Met Ala Gly Leu Leu Glu Ile
    130                 135                 140

Ile Val Ile Leu Trp Lys Ser Ile Asp Arg Ser Met Glu Asn Asn Lys
145                 150                 155                 160

Glu Ala Lys Leu Tyr Thr Ile Asn Lys Phe Ala Ser Val Leu Pro Glu
                165                 170                 175

Tyr Leu Lys Val Phe Lys Asp Asp Arg Cys Lys Ile Pro Leu Phe Met
            180                 185                 190

Leu Met Ser Phe Met Pro Ala Ser Ala Val Pro Pro Phe Ser Cys Gly
        195                 200                 205

Val Ile Ser Thr Leu Arg Ser Arg Glu Glu Gly Ala Val Asp Lys Ser
    210                 215                 220

Tyr Cys Thr Leu Xaa Asp Cys Leu Cys Xaa Trp Gly Xaa Val Gly His
225                 230                 235                 240

Ile Leu Glu Leu Xaa Asp Asn Trp Leu Ala Thr Xaa His Ala Gln Ala
                245                 250                 255

Lys Xaa Asn Thr Ala Ser Lys Xaa Gly Ala Asp Pro 
            260                 265



<210> 2288
<211> 420
<212> PRT
<213> Homo sapiens

<400> 2288
Met Asp Met Leu Arg Leu Thr Leu Gln Thr Thr Ser Asp Gly Val Met
  1               5                  10                  15

Leu Asp Lys Asp Leu Phe Lys Lys Cys Val Gln Ser Asn Ile Val Leu
             20                  25                  30

Leu Thr Gln Ala Phe Arg Arg Lys Phe Val Ile Pro Asp Phe Met Ser
         35                  40                  45

Phe Thr Ser His Ile Asp Glu Leu Tyr Glu Ser Ala Lys Lys Gln Ser
     50                  55                  60

Gly Gly Lys Val Ala Asp Tyr Ile Pro Gln Leu Ala Lys Phe Ser Pro
 65                  70                  75                  80

Asp Leu Trp Gly Val Ser Val Cys Thr Val Asp Gly Gln Arg His Ser
                 85                  90                  95

Thr Gly Asp Thr Lys Val Pro Phe Cys Leu Gln Ser Cys Val Lys Pro
            100                 105                 110

Leu Lys Tyr Ala Ile Ala Val Asn Asp Leu Gly Thr Glu Tyr Val His
        115                 120                 125

Arg Tyr Val Gly Lys Glu Pro Ser Gly Leu Arg Phe Asn Lys Leu Phe
    130                 135                 140

Leu Asn Glu Asp Asp Lys Pro His Asn Pro Met Val Asn Ala Gly Ala
145                 150                 155                 160

Ile Val Val Thr Ser Leu Ile Lys Gln Gly Val Asn Asn Ala Glu Lys
                165                 170                 175

Phe Asp Tyr Val Met Gln Phe Leu Asn Lys Met Ala Gly Asn Glu Tyr
            180                 185                 190

Val Gly Phe Ser Asn Ala Thr Phe Gln Ser Glu Arg Glu Ser Gly Asp
        195                 200                 205

Arg Asn Phe Ala Ile Gly Tyr Tyr Leu Lys Glu Lys Lys Cys Phe Pro
    210                 215                 220

Glu Gly Thr Asp Met Val Gly Ile Leu Asp Phe Tyr Phe Gln Leu Cys
225                 230                 235                 240

Ser Ile Glu Val Thr Cys Glu Ser Ala Ser Val Met Ala Ala Thr Leu
                245                 250                 255

Ala Asn Gly Gly Phe Cys Pro Ile Thr Gly Glu Arg Val Leu Ser Pro
            260                 265                 270

Glu Ala Val Arg Asn Thr Leu Ser Leu Met His Ser Cys Gly Met Tyr
        275                 280                 285

Asp Phe Ser Gly Gln Phe Ala Phe His Val Gly Leu Pro Ala Lys Ser
    290                 295                 300

Gly Val Ala Gly Gly Ile Leu Leu Val Val Pro Asn Val Met Gly Met
305                 310                 315                 320

Met Cys Trp Ser Pro Pro Leu Asp Lys Met Gly Asn Ser Val Lys Gly
                325                 330                 335

Ile His Phe Cys His Asp Leu Val Ser Leu Cys Asn Phe His Asn Tyr
            340                 345                 350

Asp Asn Leu Arg His Phe Ala Lys Lys Leu Asp Pro Arg Arg Glu Gly
        355                 360                 365

Gly Asp Gln Arg His Ser Phe Gly Pro Leu Asp Tyr Glu Ser Leu Gln
    370                 375                 380

Gln Glu Leu Ala Leu Lys Glu Thr Val Trp Lys Lys Val Ser Pro Glu
385                 390                 395                 400

Ser Asn Glu Asp Ile Ser Thr Thr Val Val Tyr Arg Met Glu Ser Leu
                405                 410                 415

Gly Glu Lys Ser 
            420



<210> 2289
<211> 375
<212> PRT
<213> Homo sapiens

<400> 2289
Met Ser Ser His Lys Gly Ser Val Val Ala Gln Gly Asn Gly Ala Pro
  1               5                  10                  15

Ala Ser Asn Arg Glu Ala Asp Thr Val Glu Leu Ala Glu Leu Gly Pro
             20                  25                  30

Leu Leu Glu Glu Lys Gly Lys Arg Val Ile Ala Asn Pro Pro Lys Ala
         35                  40                  45

Glu Glu Glu Gln Thr Cys Pro Val Pro Gln Glu Glu Glu Glu Glu Val
     50                  55                  60

Arg Val Leu Thr Leu Pro Leu Gln Ala His His Ala Met Glu Lys Met
 65                  70                  75                  80

Glu Glu Phe Val Tyr Lys Val Trp Glu Gly Arg Trp Arg Val Ile Pro
                 85                  90                  95

Tyr Asp Val Leu Pro Asp Trp Leu Lys Asp Asn Asp Tyr Leu Leu His
            100                 105                 110

Gly His Arg Pro Pro Met Pro Ser Phe Arg Ala Cys Phe Lys Ser Ile
        115                 120                 125

Phe Arg Ile His Thr Glu Thr Gly Asn Ile Trp Thr His Leu Leu Gly
    130                 135                 140

Phe Val Leu Phe Leu Phe Leu Gly Ile Leu Thr Met Leu Arg Pro Asn
145                 150                 155                 160

Met Tyr Phe Met Ala Pro Leu Gln Glu Lys Val Val Phe Gly Met Phe
                165                 170                 175

Phe Leu Gly Ala Val Leu Cys Leu Ser Phe Ser Trp Leu Phe His Thr
            180                 185                 190

Val Tyr Cys His Ser Glu Lys Val Ser Arg Thr Phe Ser Lys Leu Asp
        195                 200                 205

Tyr Ser Gly Ile Ala Leu Leu Ile Met Gly Ser Phe Val Pro Trp Leu
    210                 215                 220

Tyr Tyr Ser Phe Tyr Cys Ser Pro Gln Pro Arg Leu Ile Tyr Leu Ser
225                 230                 235                 240

Ile Val Cys Val Leu Gly Ile Ser Ala Ile Ile Val Ala Gln Trp Asp
                245                 250                 255

Arg Phe Ala Thr Pro Lys His Arg Gln Thr Arg Ala Gly Val Phe Leu
            260                 265                 270

Gly Leu Gly Leu Ser Gly Val Val Pro Thr Met His Phe Thr Ile Ala
        275                 280                 285

Glu Gly Phe Val Lys Ala Thr Thr Val Gly Gln Met Gly Trp Phe Phe
    290                 295                 300

Leu Met Ala Val Met Tyr Ile Thr Gly Ala Gly Leu Tyr Ala Ala Arg
305                 310                 315                 320

Ile Pro Glu Arg Phe Phe Pro Gly Lys Phe Asp Ile Trp Phe Gln Ser
                325                 330                 335

His Gln Ile Phe His Val Leu Val Val Ala Ala Ala Phe Val His Phe
            340                 345                 350

Tyr Gly Val Ser Asn Leu Gln Glu Phe Arg Tyr Gly Leu Glu Gly Gly
        355                 360                 365

Cys Thr Asp Asp Thr Leu Leu 
    370                 375



<210> 2290
<211> 118
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2290
Met Phe Leu Gln Leu Val Thr Gly Arg Ser Xaa Ile Arg Ala Xaa Val
  1               5                  10                  15

Arg Leu Thr Pro Lys Pro Ile Cys Ala Phe His Tyr Thr Thr Ile Thr
             20                  25                  30

Thr Asn Ile Cys Ser Val Gln Phe Thr Thr Leu Trp Ser Thr Leu Leu
         35                  40                  45

Leu Leu Leu Leu Leu Leu Pro Leu Leu Thr Ser Ser Leu Val Ser Xaa
     50                  55                  60

Tyr Ser Xaa Asp Tyr His Asp Pro His Phe Thr Gly Arg Glu Thr Glu
 65                  70                  75                  80

Thr Arg Lys Leu Ala Gln Asp His Thr Ala Gly Lys Trp Arg Arg Thr
                 85                  90                  95

Arg Thr Ser Asp Arg Leu Pro Asp Ser Arg Ser Phe Phe Ser Phe His
            100                 105                 110

Asp Ile Thr Leu Leu Pro 
        115



<210> 2291
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2291
Met Pro Glu Asp Arg Ala Ser Thr Pro Arg Thr Thr Thr Met Thr Phe
  1               5                  10                  15

Thr Cys Xaa Xaa Phe Phe Asp Leu Phe Asn Ala Leu Thr Cys Arg Ser
             20                  25                  30

Gln Thr Lys Leu Ile Phe Glu Ile Gly Phe Leu Arg Asn His Met Phe
         35                  40                  45

Leu Tyr Ser Val Leu Gly Ser Ile Leu Gly Gln Leu Ala Val Ile Tyr
     50                  55                  60

Ile Pro Pro Leu Gln Arg Val Phe Gln Thr Glu Asn Leu Gly Ala Leu
 65                  70                  75                  80

Asp Leu Leu Phe Leu Thr Gly Leu Ala Ser Ser Val Phe Ile Leu Ser
                 85                  90                  95

Glu Leu Leu Lys Leu Cys Glu Lys Tyr Cys Cys Ser Pro Lys Arg Val
            100                 105                 110

Gln Met His Pro Glu Asp Val 
        115



<210> 2292
<211> 191
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (171)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2292
Met Leu His Ala Glu Ala Pro Ala Pro Ala Arg Phe Pro Ala Phe Ser
  1               5                  10                  15

Met Gly His Gly Gly Ala Phe Gly Glu Gly Leu Cys Gly Phe Pro Pro
             20                  25                  30

Lys Ser Arg Leu Met Pro Leu Ile Pro Ser Gln Glu Val Ala Glu Gly
         35                  40                  45

Leu Gly Ser Val Gln Ala Pro Arg Gly Gly Asp Val Gln Val Lys Gln
     50                  55                  60

Gly Val Cys Arg Arg Arg Gly Ser Leu Pro Trp Ala Gly Cys Gln His
 65                  70                  75                  80

Leu Gly Val Pro Gly Cys Gln Glu Lys Phe Thr His Thr Arg Ala Leu
                 85                  90                  95

Leu Ala Lys Gly Glu Ser Tyr Asp Gly Arg Ala Arg Ala Leu Ser Arg
            100                 105                 110

His Gln Val Cys Ser Gln Ser Ser Arg Ser Ala Pro Val Thr Trp Asn
        115                 120                 125

Arg Pro Ala Phe Arg Gly Leu Ser Phe Leu Ile Cys Leu Met Gly Ile
    130                 135                 140

Ala Ile Pro Thr Phe Pro Val Leu Val Gly Phe Ser Leu Asp Ala Gln
145                 150                 155                 160

Glu Thr Ala Ala Xaa Glu Gly Leu Phe Gly Xaa Leu Phe His Val Thr
                165                 170                 175

Pro Leu Leu Pro Cys Pro His Gly Ala Gly Gly Ala Gly Ala Trp 
            180                 185                 190



<210> 2293
<211> 270
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2293
Met Thr Gln Asn Thr Val Ile Val Asn Gly Val Ala Met Ala Ser Arg
  1               5                  10                  15

Pro Ser Gln Pro Thr His Val Asn Val His Ile His Gln Glu Ser Ala
             20                  25                  30

Leu Thr Gln Leu Leu Lys Ala Gly Gly Ser Leu Lys Lys Phe Leu Phe
         35                  40                  45

His Pro Gly Asp Thr Val Pro Ser Thr Ala Arg Ile Gly Tyr Glu Gln
     50                  55                  60

Leu Ala Leu Gly Val Thr Gln Ile Leu Leu Gly Val Val Ser Cys Val
 65                  70                  75                  80

Leu Gly Val Cys Leu Ser Leu Gly Pro Trp Thr Val Leu Xaa Ala Ser
                 85                  90                  95

Gly Cys Ala Phe Trp Ala Gly Ser Val Val Ile Ala Ala Gly Ala Gly
            100                 105                 110

Ala Ile Val His Glu Lys His Pro Gly Lys Leu Ala Gly Tyr Ile Ser
        115                 120                 125

Ser Leu Leu Thr Leu Xaa Gly Phe Ala Thr Ala Met Ala Ala Val Val
    130                 135                 140

Leu Cys Val Asn Ser Phe Ile Trp Gln Thr Glu Pro Phe Leu Tyr Ile
145                 150                 155                 160

Asp Thr Val Cys Asp Arg Ser Asp Pro Val Phe Pro Thr Thr Gly Tyr
                165                 170                 175

Arg Trp Met Arg Arg Ser Gln Glu Asn Gln Trp Gln Lys Glu Glu Cys
            180                 185                 190

Arg Ala Tyr Met Gln Met Leu Arg Lys Leu Phe Thr Ala Ile Arg Ala
        195                 200                 205

Leu Phe Leu Ala Val Cys Val Leu Lys Val Ile Val Ser Leu Val Ser
    210                 215                 220

Leu Gly Val Gly Leu Arg Asn Leu Cys Gly Gln Ser Ser Gln Pro Leu
225                 230                 235                 240

Asn Glu Glu Gly Ser Glu Lys Arg Leu Leu Gly Glu Asn Ser Val Pro
                245                 250                 255

Pro Ser Pro Ser Arg Glu Gln Thr Ser Thr Ala Ile Val Leu 
            260                 265                 270



<210> 2294
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2294
Met Ile Gly Ile Phe Lys Asn Ile Ile Ser Lys Pro Asn Glu Lys Glu
  1               5                  10                  15

Glu Ala Ile Val Leu Glu Ile Gln Ser Asp Ile Leu Leu Ile Leu Ser
             20                  25                  30

Gly Xaa Cys Glu Asn His Ile Gln Arg Lys Glu Ile Phe Gly Thr Glu
         35                  40                  45

Gly Val Asp Ile Val Leu His Val Met Lys Thr Asp Pro Arg Lys Leu
     50                  55                  60

Gln Ser Gly Leu Gly Tyr Asn Val Leu Leu Phe Ser Thr Leu Asp Ser
 65                  70                  75                  80

Ile Trp Cys Cys Ile Leu Gly Cys Tyr Pro Ser Glu Asp Tyr Phe Leu
                 85                  90                  95

Glu Lys Glu Gly Ile Phe Leu Leu Leu Asp Leu Leu Ala Leu Asn Gln
            100                 105                 110

Lys Asn Ser Val Ile 
        115



<210> 2295
<211> 113
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2295
Met Tyr Ile Thr Ser Thr Ile Lys Thr Xaa Ser Ser Arg Leu Ala Lys
  1               5                  10                  15

Pro Val Leu Cys Leu Gly Thr Leu Cys Thr Ala Phe Leu Thr Gly Leu
             20                  25                  30

Asn Arg Val Ser Glu Tyr Arg Asn His Cys Ser Asp Val Ile Ala Gly
         35                  40                  45

Phe Ile Leu Gly Thr Ala Val Ala Leu Phe Leu Gly Met Cys Val Val
     50                  55                  60

His Asn Phe Lys Gly Thr Gln Gly Ser Pro Ser Lys Pro Lys Pro Glu
 65                  70                  75                  80

Asp Pro Arg Gly Val Pro Leu Met Ala Phe Pro Arg Ile Glu Ser Pro
                 85                  90                  95

Leu Glu Thr Leu Ser Ala Gln Asn His Ser Ala Ser Met Thr Glu Val
            100                 105                 110

Thr 




<210> 2296
<211> 293
<212> PRT
<213> Homo sapiens

<400> 2296
Met Thr Glu Asp Ser Gln Arg Asn Phe Arg Ser Val Tyr Tyr Glu Lys
  1               5                  10                  15

Val Gly Phe Arg Gly Val Glu Glu Lys Lys Ser Leu Glu Ile Leu Leu
             20                  25                  30

Lys Asp Asp Arg Leu Asp Thr Glu Lys Leu Cys Thr Phe Ser Gln Arg
         35                  40                  45

Phe Pro Leu Pro Ser Met Tyr Arg Ala Leu Val Trp Lys Val Leu Leu
     50                  55                  60

Gly Ile Leu Pro Pro His His Glu Ser His Ala Lys Val Met Met Tyr
 65                  70                  75                  80

Arg Lys Glu Gln Tyr Leu Asp Val Leu His Ala Leu Lys Val Val Arg
                 85                  90                  95

Phe Val Ser Asp Ala Thr Pro Gln Ala Glu Val Tyr Leu Arg Met Tyr
            100                 105                 110

Gln Leu Glu Ser Gly Lys Leu Pro Arg Ser Pro Ser Phe Pro Leu Glu
        115                 120                 125

Pro Asp Asp Glu Val Phe Leu Ala Ile Ala Lys Ala Met Glu Glu Met
    130                 135                 140

Val Glu Asp Ser Val Asp Cys Tyr Trp Ile Thr Arg Arg Phe Val Asn
145                 150                 155                 160

Gln Leu Asn Thr Lys Tyr Arg Asp Ser Leu Pro Gln Leu Pro Lys Ala
                165                 170                 175

Phe Glu Gln Tyr Leu Asn Leu Glu Asp Gly Arg Leu Leu Thr His Leu
            180                 185                 190

Arg Met Cys Ser Ala Ala Pro Lys Leu Pro Tyr Asp Leu Trp Phe Lys
        195                 200                 205

Arg Cys Phe Ala Gly Cys Leu Pro Glu Ser Ser Leu Gln Arg Val Trp
    210                 215                 220

Asp Lys Val Val Ser Gly Ser Cys Lys Ile Leu Val Phe Val Ala Val
225                 230                 235                 240

Glu Ile Leu Leu Thr Phe Lys Ile Lys Val Met Ala Leu Asn Ser Ala
                245                 250                 255

Glu Lys Ile Thr Lys Phe Leu Glu Asn Ile Pro Gln Asp Ser Ser Asp
            260                 265                 270

Ala Ile Val Ser Lys Ala Ile Asp Leu Trp His Lys His Cys Gly Thr
        275                 280                 285

Pro Val His Ser Ser 
    290



<210> 2297
<211> 100
<212> PRT
<213> Homo sapiens

<400> 2297
Met Leu Gln Asn Val Asn Cys Phe Lys Leu Lys Leu Pro Leu Lys Arg
  1               5                  10                  15

Pro Arg Tyr Ile Tyr Leu Ile Val Tyr Ile Met Phe Asn Ile Cys Gln
             20                  25                  30

Ser Ile Leu Gln Val Cys Ser Phe Ile Ser Ile Lys Tyr Gly Tyr Tyr
         35                  40                  45

Val Ala Gln Leu Leu Lys Trp Tyr Cys Ile Val Tyr Ile Cys Thr Pro
     50                  55                  60

Asn Asn Ile Val Cys Thr Phe Cys Phe Leu Tyr Cys Ile Cys Ala Gly
 65                  70                  75                  80

Phe Phe Arg Leu Tyr Gln Cys Asn Leu Cys Leu Leu Arg Tyr Val Gln
                 85                  90                  95

Lys Met Ser Ile 
            100



<210> 2298
<211> 104
<212> PRT
<213> Homo sapiens

<400> 2298
Met Trp His Leu Leu Val Phe Ile Val Cys Val Phe Phe Val Tyr Tyr
  1               5                  10                  15

Thr Leu Gly Asn Phe Val Leu Pro Lys Lys Lys Lys Lys Arg Lys Cys
             20                  25                  30

Asn Val Arg His Thr Arg Lys Ala Asn Gln Cys Cys Lys Leu Lys Val
         35                  40                  45

Gln Phe Gln Arg Ser Leu Pro Thr Ala Gly Phe Phe Leu Tyr Phe Lys
     50                  55                  60

Asn Ile Met Leu His Ile Ile Ala Ile Phe Ile Phe Trp Gly Phe Ala
 65                  70                  75                  80

Thr Leu Ile Gln Trp Asn Gln Trp Lys Cys His Pro Ala Thr Glu Leu
                 85                  90                  95

Pro Leu Leu Tyr Leu Lys Ser Phe 
            100



<210> 2299
<211> 667
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (250)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2299
Met Lys Met His Ala Glu Lys Lys His Lys Cys Ser Lys Cys Ser Asn
  1               5                  10                  15

Ser Tyr Gly Thr Glu Trp Asp Leu Lys Arg His Ala Glu Asp Cys Gly
             20                  25                  30

Lys Thr Phe Arg Cys Thr Cys Gly Cys Pro Tyr Ala Ser Arg Thr Ala
         35                  40                  45

Leu Gln Ser His Ile Tyr Arg Thr Gly His Glu Ile Pro Ala Glu His
     50                  55                  60

Arg Asp Pro Pro Ser Lys Lys Arg Lys Met Glu Asn Cys Ala Gln Asn
 65                  70                  75                  80

Gln Lys Leu Ser Asn Lys Thr Ile Glu Ser Leu Asn Asn Gln Pro Ile
                 85                  90                  95

Pro Arg Pro Asp Thr Gln Glu Leu Glu Ala Ser Glu Ile Lys Leu Glu
            100                 105                 110

Pro Ser Phe Glu Asp Ser Cys Gly Ser Asn Thr Asp Lys Gln Thr Leu
        115                 120                 125

Thr Thr Pro Pro Arg Tyr Pro Gln Lys Leu Leu Leu Pro Lys Pro Lys
    130                 135                 140

Val Ala Leu Val Lys Leu Pro Val Met Gln Phe Ser Val Met Pro Val
145                 150                 155                 160

Phe Val Pro Thr Ala Asp Ser Ser Ala Gln Pro Val Val Leu Gly Val
                165                 170                 175

Asp Gln Gly Ser Ala Thr Gly Ala Val His Leu Met Pro Leu Ser Val
            180                 185                 190

Gly Thr Leu Ile Leu Gly Leu Asp Ser Glu Ala Cys Ser Leu Lys Glu
        195                 200                 205

Ser Leu Pro Leu Phe Lys Ile Ala Asn Pro Ile Ala Gly Glu Pro Ile
    210                 215                 220

Ser Thr Gly Val Gln Val Asn Phe Gly Lys Ser Pro Ser Asn Pro Leu
225                 230                 235                 240

Gln Glu Leu Gly Asn Thr Cys Gln Lys Xaa Ser Ile Ser Ser Ile Asn
                245                 250                 255

Val Gln Thr Asp Leu Ser Tyr Ala Ser Gln Asn Phe Ile Pro Ser Ala
            260                 265                 270

Gln Trp Ala Thr Ala Asp Ser Ser Val Ser Ser Cys Ser Gln Thr Asp
        275                 280                 285

Leu Ser Phe Asp Ser Gln Val Ser Leu Pro Ile Ser Val His Thr Gln
    290                 295                 300

Thr Phe Leu Pro Ser Ser Lys Val Thr Ser Ser Ile Ala Ala Gln Thr
305                 310                 315                 320

Asp Ala Phe Met Asp Thr Cys Phe Gln Ser Gly Gly Val Ser Arg Glu
                325                 330                 335

Thr Gln Thr Ser Gly Ile Glu Ser Pro Thr Asp Asp His Val Gln Met
            340                 345                 350

Asp Gln Ala Gly Met Cys Gly Asp Ile Phe Glu Ser Val His Ser Ser
        355                 360                 365

Tyr Asn Val Ala Thr Gly Asn Ile Ile Ser Asn Ser Leu Val Ala Glu
    370                 375                 380

Thr Val Thr His Ser Leu Leu Pro Gln Asn Glu Pro Lys Thr Leu Asn
385                 390                 395                 400

Gln Asp Ile Glu Lys Ser Ala Pro Ile Ile Asn Phe Ser Ala Gln Asn
                405                 410                 415

Ser Met Leu Pro Ser Gln Asn Met Thr Asp Asn Gln Thr Gln Thr Ile
            420                 425                 430

Asp Leu Leu Ser Asp Leu Glu Asn Ile Leu Ser Ser Asn Leu Pro Ala
        435                 440                 445

Gln Thr Leu Asp His Arg Ser Leu Leu Ser Asp Thr Asn Pro Gly Pro
    450                 455                 460

Asp Thr Gln Leu Pro Ser Gly Pro Ala Gln Asn Pro Gly Ile Asp Phe
465                 470                 475                 480

Asp Ile Glu Glu Phe Phe Ser Ala Ser Asn Ile Gln Thr Gln Thr Glu
                485                 490                 495

Glu Ser Glu Leu Ser Thr Met Thr Thr Glu Pro Val Leu Glu Ser Leu
            500                 505                 510

Asp Ile Glu Thr Gln Thr Asp Phe Leu Leu Ala Asp Thr Ser Ala Gln
        515                 520                 525

Ser Tyr Gly Cys Arg Gly Asn Ser Asn Phe Leu Gly Leu Glu Met Phe
    530                 535                 540

Asp Thr Gln Thr Gln Thr Asp Leu Asn Phe Phe Leu Asp Ser Ser Pro
545                 550                 555                 560

His Leu Pro Leu Gly Ser Ile Leu Lys His Ser Ser Phe Ser Val Ser
                565                 570                 575

Thr Asp Ser Ser Asp Thr Glu Thr Gln Thr Glu Gly Val Ser Thr Ala
            580                 585                 590

Lys Asn Ile Pro Ala Leu Glu Ser Lys Val Gln Leu Asn Ser Thr Glu
        595                 600                 605

Thr Gln Thr Met Ser Ser Gly Phe Glu Thr Leu Gly Ser Leu Phe Phe
    610                 615                 620

Thr Ser Asn Glu Thr Gln Thr Ala Met Asp Asp Phe Leu Leu Ala Asp
625                 630                 635                 640

Leu Ala Trp Asn Thr Met Glu Ser Gln Phe Ser Ser Val Glu Thr Gln
                645                 650                 655

Thr Ser Ala Glu Pro His Thr Val Ser Asn Phe 
            660                 665



<210> 2300
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (17)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2300
Met Ser Leu Pro Thr Ser His Cys Ser Tyr Pro Phe Leu Gly Val Cys
  1               5                  10                  15

Xaa Ala Glu Pro Ala Ala Leu Leu Thr Phe Phe Xaa Pro Lys Asp Glu
             20                  25                  30

Xaa Trp Gln Leu Trp Xaa Asp Phe Gly Gln Val Ala Val His Pro Ala
         35                  40                  45

Asp Gly Asn Cys Ser Pro Pro Asn Pro Gln His Lys His Ser Gln Thr
     50                  55                  60

His Ile His Phe Trp Ala Gly Ile Trp Gly Asn Trp Pro Ser Ser Leu
 65                  70                  75                  80

Gln Phe Phe Ala Pro Cys Phe Leu Trp Phe Gly Arg Val Gly Val Ser
                 85                  90                  95

Val Ile Ser Thr Gly Phe Asn Arg His Leu 
            100                 105



<210> 2301
<211> 833
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2301
Met Thr Lys Lys Arg Lys Arg Gln His Asp Phe Gln Lys Val Lys Leu
  1               5                  10                  15

Lys Val Gly Lys Lys Lys Pro Lys Leu Gln Asn Ala Thr Pro Thr Asn
             20                  25                  30

Phe Lys Thr Lys Thr Ile His Leu Pro Glu Gln Leu Lys Glu Asp Gly
         35                  40                  45

Thr Leu Pro Thr Asn Asn Arg Lys Leu Asn Ile Lys Asp Leu Leu Ser
     50                  55                  60

Gln Met His His Tyr Asn Ala Gly Val Lys Gln Ser Ala Leu Leu Gly
 65                  70                  75                  80

Leu Lys Asp Leu Leu Ser Gln Tyr Pro Phe Ile Ile Asp Ala His Leu
                 85                  90                  95

Ser Asn Ile Leu Ser Glu Val Thr Ala Val Phe Thr Asp Lys Asp Ala
            100                 105                 110

Asn Val Arg Leu Xaa Ala Val Gln Leu Leu Gln Phe Leu Ala Pro Lys
        115                 120                 125

Ile Arg Ala Glu Gln Ile Ser Pro Phe Phe Pro Leu Ala Leu Ala Asp
    130                 135                 140

Gly Ser Ser Arg Leu Arg Glu Ser Glu Gly Leu Gln Glu Gln Lys Glu
145                 150                 155                 160

Asn Pro His Ala Thr Ser Asn Ser Ile Phe Ile Asn Trp Lys Glu His
                165                 170                 175

Ala Asn Asp Gln Gln His Ile Gln Val Tyr Glu Asn Gly Gly Ser Gln
            180                 185                 190

Pro Asn Val Ser Ser Gln Phe Arg Leu Arg Tyr Leu Val Gly Gly Leu
        195                 200                 205

Ser Gly Val Asp Glu Gly Leu Ser Ser Thr Glu Asn Leu Lys Gly Phe
    210                 215                 220

Ile Glu Ile Ile Ile Pro Leu Leu Ile Glu Cys Trp Val Glu Ala Val
225                 230                 235                 240

Pro Pro Gln Leu Ala Thr Pro Val Gly Asn Gly Ile Glu Arg Glu Pro
                245                 250                 255

Leu Gln Val Met Gln Gln Val Leu Asn Ile Ile Ser Leu Leu Trp Lys
            260                 265                 270

Leu Ser Lys Gln Gln Asp Glu Thr His Lys Leu Glu Ser Trp Leu Arg
        275                 280                 285

Lys Asn Tyr Leu Ile Asp Phe Lys His His Phe Met Ser Arg Phe Pro
    290                 295                 300

Tyr Val Leu Lys Glu Ile Thr Lys His Lys Arg Lys Glu Pro Asn Lys
305                 310                 315                 320

Ser Ile Lys His Cys Thr Val Leu Ser Asn Asn Ile Asp His Leu Leu
                325                 330                 335

Leu Asn Leu Thr Leu Ser Asp Ile Met Val Ser Leu Ala Asn Ala Ser
            340                 345                 350

Thr Leu Gln Lys Asp Cys Ser Trp Ile Glu Met Ile Arg Lys Phe Val
        355                 360                 365

Thr Glu Thr Leu Glu Asp Gly Ser Arg Leu Asn Ser Lys Gln Leu Asn
    370                 375                 380

Arg Leu Leu Gly Val Ser Trp Arg Leu Met Gln Ile Gln Pro Asn Arg
385                 390                 395                 400

Glu Asp Thr Glu Thr Leu Ile Lys Ala Val Tyr Thr Leu Tyr Gln Gln
                405                 410                 415

Arg Gly Leu Ile Leu Pro Val Arg Thr Leu Leu Leu Lys Phe Phe Ser
            420                 425                 430

Lys Ile Tyr Gln Thr Glu Glu Leu Arg Ser Cys Arg Phe Arg Tyr Arg
        435                 440                 445

Ser Lys Val Leu Ser Arg Trp Leu Ala Gly Leu Pro Leu Gln Leu Ala
    450                 455                 460

His Leu Gly Ser Arg Asn Pro Glu Leu Ser Thr Gln Leu Ile Asp Ile
465                 470                 475                 480

Ile His Thr Ala Ala Ala Arg Ala Asn Lys Glu Leu Leu Lys Ser Leu
                485                 490                 495

Gln Ala Thr Ala Leu Arg Ile Tyr Asp Pro Gln Glu Gly Ala Val Val
            500                 505                 510

Val Leu Pro Ala Asp Ser Gln Gln Arg Leu Val Gln Leu Val Tyr Phe
        515                 520                 525

Leu Pro Ser Leu Pro Ala Asp Leu Leu Ser Arg Leu Ser Arg Cys Cys
    530                 535                 540

Ile Met Gly Arg Leu Ser Ser Ser Leu Ala Ala Met Leu Ile Gly Ile
545                 550                 555                 560

Leu His Met Arg Ser Ser Phe Ser Gly Trp Lys Tyr Ser Ala Lys Asp
                565                 570                 575

Trp Leu Met Ser Asp Val Asp Tyr Phe Ser Phe Leu Phe Ser Thr Leu
            580                 585                 590

Thr Gly Phe Ser Lys Glu Glu Leu Thr Trp Leu Gln Ser Leu Arg Gly
        595                 600                 605

Val Pro His Val Ile Gln Thr Gln Leu Ser Pro Val Leu Leu Tyr Leu
    610                 615                 620

Thr Asp Leu Asp Gln Phe Leu His His Trp Asp Val Thr Glu Ala Val
625                 630                 635                 640

Phe His Ser Leu Leu Val Ile Pro Ala Arg Ser Gln Asn Phe Asp Ile
                645                 650                 655

Leu Gln Ser Ala Ile Ser Lys His Leu Val Gly Leu Thr Val Ile Pro
            660                 665                 670

Asp Ser Thr Ala Gly Cys Val Phe Gly Val Ile Cys Lys Leu Leu Asp
        675                 680                 685

His Thr Cys Val Val Ser Glu Thr Leu Leu Pro Phe Leu Ala Ser Cys
    690                 695                 700

Cys Tyr Ser Leu Leu Tyr Phe Leu Leu Thr Ile Glu Lys Gly Glu Ala
705                 710                 715                 720

Glu His Leu Arg Lys Arg Asp Lys Leu Trp Gly Val Cys Val Ser Ile
                725                 730                 735

Leu Ala Leu Leu Pro Arg Val Leu Arg Leu Met Leu Gln Ser Leu Arg
            740                 745                 750

Val Asn Arg Val Gly Pro Glu Glu Leu Pro Val Val Gly Gln Leu Leu
        755                 760                 765

Arg Leu Leu Leu Gln His Ala Pro Leu Arg Thr His Met Leu Thr Asn
    770                 775                 780

Ala Ile Leu Val Gln Gln Ile Ile Lys Asn Ile Thr Thr Leu Lys Ser
785                 790                 795                 800

Gly Ser Val Gln Glu Gln Trp Leu Thr Asp Leu His Tyr Cys Phe Asn
                805                 810                 815

Val Tyr Ile Thr Gly His Pro Gln Gly Pro Ser Ala Leu Ala Thr Val
            820                 825                 830

Tyr 




<210> 2302
<211> 191
<212> PRT
<213> Homo sapiens

<400> 2302
Met Gly Ile Leu Tyr Ser Glu Pro Ile Cys Gln Ala Ala Tyr Gln Asn
  1               5                  10                  15

Asp Phe Gly Gln Val Trp Arg Trp Val Lys Glu Asp Ser Ser Tyr Ala
             20                  25                  30

Asn Val Gln Asp Gly Phe Asn Gly Asp Thr Pro Leu Ile Cys Ala Cys
         35                  40                  45

Arg Arg Gly His Val Arg Ile Val Ser Phe Leu Leu Arg Arg Asn Ala
     50                  55                  60

Asn Val Asn Leu Lys Asn Gln Lys Glu Arg Thr Cys Leu His Tyr Ala
 65                  70                  75                  80

Val Lys Lys Lys Phe Thr Phe Ile Asp Tyr Leu Leu Ile Ile Leu Leu
                 85                  90                  95

Met Pro Val Leu Leu Ile Gly Tyr Phe Leu Met Val Ser Lys Thr Lys
            100                 105                 110

Gln Asn Glu Ala Leu Val Arg Met Leu Leu Asp Ala Gly Val Glu Val
        115                 120                 125

Asn Ala Thr Asp Cys Tyr Gly Cys Thr Ala Leu His Tyr Ala Cys Glu
    130                 135                 140

Met Lys Asn Gln Ser Leu Ile Pro Leu Leu Leu Glu Ala Arg Ala Asp
145                 150                 155                 160

Pro Thr Ile Lys Asn Lys His Gly Glu Ser Ser Leu Asp Ile Ala Arg
                165                 170                 175

Arg Leu Lys Phe Ser Gln Ile Glu Leu Met Leu Arg Lys Ala Leu 
            180                 185                 190



<210> 2303
<211> 166
<212> PRT
<213> Homo sapiens

<400> 2303
Met Pro Thr Thr Lys Lys Thr Leu Met Phe Leu Ser Ser Phe Phe Thr
  1               5                  10                  15

Ser Leu Gly Ser Phe Ile Val Ile Cys Ser Ile Leu Gly Thr Gln Ala
             20                  25                  30

Trp Ile Thr Ser Thr Ile Ala Val Arg Asp Ser Ala Ser Asn Gly Ser
         35                  40                  45

Ile Phe Ile Thr Tyr Gly Leu Phe Arg Gly Glu Ser Ser Glu Glu Leu
     50                  55                  60

Ser His Gly Leu Ala Glu Pro Lys Lys Lys Phe Ala Ala Ser Phe Val
 65                  70                  75                  80

Phe Val Thr Met Ile Leu Phe Val Ala Asn Thr Gln Ser Asn Gln Leu
                 85                  90                  95

Ser Glu Glu Leu Phe Gln Met Leu Tyr Pro Ala Thr Thr Ser Lys Gly
            100                 105                 110

Thr Thr His Ser Tyr Gly Tyr Ser Phe Trp Leu Ile Leu Leu Val Ile
        115                 120                 125

Leu Leu Asn Ile Val Thr Val Thr Ile Ile Ile Phe Tyr Gln Lys Ala
    130                 135                 140

Arg Tyr Gln Arg Lys Gln Glu Gln Arg Lys Pro Met Glu Tyr Ala Pro
145                 150                 155                 160

Arg Asp Gly Ile Leu Phe 
                165



<210> 2304
<211> 174
<212> PRT
<213> Homo sapiens

<400> 2304
Met Arg Asp Leu Lys Ala Val Gly Lys Lys Phe Met His Val Leu Tyr
  1               5                  10                  15

Pro Arg Lys Ser Asn Thr Leu Leu Arg Asp Trp Asp Leu Trp Gly Pro
             20                  25                  30

Leu Ile Leu Cys Val Thr Leu Ala Leu Met Leu Gln Arg Asp Ser Ala
         35                  40                  45

Asp Ser Glu Lys Asp Gly Gly Pro Gln Phe Ala Glu Val Phe Val Ile
     50                  55                  60

Val Trp Phe Gly Ala Val Thr Ile Thr Leu Asn Ser Lys Leu Leu Gly
 65                  70                  75                  80

Gly Asn Ile Ser Phe Phe Gln Ser Leu Cys Val Leu Gly Tyr Cys Ile
                 85                  90                  95

Leu Pro Leu Thr Val Ala Met Leu Ile Cys Arg Leu Val Leu Leu Ala
            100                 105                 110

Asp Pro Gly Pro Val Asn Phe Met Val Arg Leu Phe Val Val Ile Val
        115                 120                 125

Met Phe Ala Trp Ser Ile Val Ala Ser Thr Ala Phe Leu Ala Asp Ser
    130                 135                 140

Gln Pro Pro Asn Arg Arg Ala Leu Ala Val Tyr Pro Val Phe Leu Phe
145                 150                 155                 160

Tyr Phe Val Ile Ser Trp Met Ile Leu Thr Phe Thr Pro Gln 
                165                 170



<210> 2305
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2305
Met Leu Phe Glu Asp Leu Leu Leu Asn Glu Ile Pro Glu Lys Lys Xaa
  1               5                  10                  15

Ser Glu Lys Glu Phe His Val Leu Pro Tyr Arg Val Phe Val Pro Leu
             20                  25                  30

Pro Gly Ser Thr Val Met Leu Cys Asp Tyr Lys Phe Asp Asp Glu Ser
         35                  40                  45

Ala Glu Glu Ile Arg Asp His Phe Met Glu Met Leu Asp His Thr Ile
     50                  55                  60

Gln Ile Glu Asp Leu Glu Ile Ala Glu Glu Thr Asn Thr Ala Cys Met
 65                  70                  75                  80

Ser Ser Ser Met Asn Ser Gln Ala Ser Leu Asp Asn Thr Asp Asp Glu
                 85                  90                  95

Gln Pro Lys Gln Pro Ile Lys Thr Thr Met Leu Leu Lys Ile Gln Gln
            100                 105                 110

Asn Ile Gly Val Ile Ala Ala Phe Thr Val Ala Val Leu Ala Ala Gly
        115                 120                 125

Ile Ser Phe His Tyr Phe Ser Asp 
    130                 135



<210> 2306
<211> 195
<212> PRT
<213> Homo sapiens

<400> 2306
Met Thr Asp Leu Asn Asp Asn Ile Cys Lys Arg Tyr Ile Lys Met Ile
  1               5                  10                  15

Thr Asn Ile Val Ile Leu Ser Leu Ile Ile Cys Ile Ser Leu Ala Phe
             20                  25                  30

Trp Ile Ile Ser Met Thr Ala Ser Thr Tyr Tyr Gly Asn Leu Arg Pro
         35                  40                  45

Ile Ser Pro Trp Arg Trp Leu Phe Ser Val Val Val Pro Val Leu Ile
     50                  55                  60

Val Ser Asn Gly Leu Lys Lys Lys Ser Leu Asp His Ser Gly Ala Leu
 65                  70                  75                  80

Gly Gly Leu Val Val Gly Phe Ile Leu Thr Ile Ala Asn Phe Ser Phe
                 85                  90                  95

Phe Thr Ser Leu Leu Met Phe Phe Leu Ser Ser Ser Lys Leu Thr Lys
            100                 105                 110

Trp Lys Gly Glu Val Lys Lys Arg Leu Asp Ser Glu Tyr Lys Glu Gly
        115                 120                 125

Gly Gln Arg Asn Trp Val Gln Val Phe Cys Asn Gly Ala Val Pro Thr
    130                 135                 140

Glu Leu Ala Leu Leu Tyr Met Ile Glu Asn Gly Pro Gly Glu Ile Gln
145                 150                 155                 160

Ser Ile Phe Pro Ser Ser Thr Pro Leu Pro Gly Cys Val Cys Leu Ser
                165                 170                 175

Trp Leu His Trp Pro Ala Leu Leu Glu Thr His Gly Leu Gln Lys Leu
            180                 185                 190

Ala Gln Phe 
        195



<210> 2307
<211> 282
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (233)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (271)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2307
Met Gly Asn Gly Gly Arg Ser Gly Leu Gln Gln Gly Lys Gly Asn Val
  1               5                  10                  15

Asp Gly Val Ala Ala Thr Pro Thr Ala Ala Ser Ala Ser Cys Gln Tyr
             20                  25                  30

Arg Cys Ile Glu Cys Asn Gln Glu Ala Lys Glu Leu Tyr Arg Asp Tyr
         35                  40                  45

Asn His Gly Val Leu Lys Ile Thr Ile Cys Lys Ser Cys Gln Lys Pro
     50                  55                  60

Val Asp Lys Tyr Ile Glu Tyr Asp Pro Val Ile Ile Leu Ile Asn Ala
 65                  70                  75                  80

Ile Leu Cys Lys Ala Gln Ala Tyr Arg His Ile Leu Phe Asn Thr Gln
                 85                  90                  95

Ile Asn Ile His Gly Lys Leu Cys Ile Phe Cys Leu Leu Cys Glu Ala
            100                 105                 110

Tyr Leu Arg Trp Trp Gln Leu Gln Asp Ser Asn Gln Asn Thr Ala Pro
        115                 120                 125

Asp Asp Leu Ile Arg Tyr Ala Lys Glu Trp Asp Phe Tyr Arg Met Phe
    130                 135                 140

Ala Ile Ala Ala Leu Glu Gln Thr Ala Tyr Phe Ile Gly Ile Phe Thr
145                 150                 155                 160

Phe Leu Trp Val Glu Arg Pro Met Thr Ala Lys Lys Lys Pro Asn Phe
                165                 170                 175

Ile Leu Leu Leu Lys Ala Leu Leu Leu Ser Ser Tyr Gly Lys Leu Leu
            180                 185                 190

Leu Ile Pro Ala Val Ile Trp Glu His Asp Tyr Thr Ser Val Cys Leu
        195                 200                 205

Lys Leu Ile Lys Val Phe Val Leu Thr Ser Asn Phe Gln Ala Ile Arg
    210                 215                 220

Val Thr Leu Asn Ile Asn Arg Lys Xaa Ser Phe Leu Ala Val Leu Ser
225                 230                 235                 240

Gly Leu Leu Leu Glu Arg Ser Trp Ser Thr Ser Ser Arg Val Trp Asn
                245                 250                 255

Gly Met Leu Glu Val Ile Met Pro Ser Leu Asn Leu Arg Thr Xaa Glu
            260                 265                 270

Glu Phe Tyr Ser Ser Ser Leu Ser Val Ala 
        275                 280



<210> 2308
<211> 523
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (147)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (247)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (326)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (411)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2308
Met Tyr Thr Met Leu Arg Asp Ser Asn Ala Thr Ala Ala Lys Met Ser
  1               5                  10                  15

Leu Asp Val Met Ile Glu Leu Tyr Arg Arg Asn Ile Trp Asn Asp Ala
             20                  25                  30

Lys Thr Val Asn Val Ile Thr Thr Ala Cys Phe Ser Lys Val Thr Lys
         35                  40                  45

Ile Leu Val Ala Ala Leu Thr Phe Phe Leu Gly Lys Asp Glu Asp Glu
     50                  55                  60

Lys Gln Asp Ser Asp Ser Glu Ser Glu Asp Asp Gly Pro Thr Ala Arg
 65                  70                  75                  80

Asp Leu Leu Val Gln Tyr Ala Thr Gly Lys Lys Ser Ser Lys Asn Lys
                 85                  90                  95

Lys Lys Leu Glu Lys Ala Met Lys Val Leu Lys Lys Gln Lys Lys Lys
            100                 105                 110

Lys Lys Pro Glu Val Phe Asn Phe Ser Ala Ile His Leu Ile His Asp
        115                 120                 125

Pro Gln Asp Phe Ala Glu Lys Leu Leu Lys Gln Leu Glu Cys Cys Lys
    130                 135                 140

Glu Arg Xaa Glu Val Lys Met Met Leu Met Asn Leu Ile Ser Arg Leu
145                 150                 155                 160

Val Gly Ile His Glu Leu Phe Leu Phe Xaa Phe Tyr Pro Phe Leu Gln
                165                 170                 175

Arg Phe Leu Gln Pro His Gln Arg Glu Val Thr Lys Ile Leu Leu Phe
            180                 185                 190

Ala Ala Gln Ala Ser His His Leu Val Pro Pro Glu Ile Ile Gln Ser
        195                 200                 205

Leu Leu Met Thr Val Ala Asn Asn Phe Val Thr Asp Lys Asn Ser Gly
    210                 215                 220

Glu Val Met Thr Val Gly Ile Asn Ala Ile Lys Glu Ile Thr Ala Arg
225                 230                 235                 240

Cys Pro Leu Ala Met Thr Xaa Glu Leu Leu Gln Asp Leu Ala Gln Tyr
                245                 250                 255

Lys Thr His Lys Asp Lys Asn Val Met Met Ser Ala Arg Thr Leu Ile
            260                 265                 270

His Leu Phe Arg Thr Leu Asn Pro Gln Met Leu Gln Lys Lys Phe Arg
        275                 280                 285

Gly Lys Pro Thr Glu Ala Ser Ile Glu Ala Arg Val Gln Glu Tyr Gly
    290                 295                 300

Glu Leu Asp Ala Lys Asp Tyr Ile Pro Gly Ala Glu Val Leu Glu Val
305                 310                 315                 320

Glu Lys Glu Glu Asn Xaa Glu Asn Asp Glu Asp Gly Trp Glu Ser Thr
                325                 330                 335

Ser Leu Ser Glu Glu Glu Asp Ala Asp Gly Glu Trp Ile Asp Val Gln
            340                 345                 350

His Ser Ser Asp Glu Glu Gln Gln Glu Ile Ser Lys Lys Leu Asn Ser
        355                 360                 365

Met Pro Met Glu Glu Arg Lys Ala Lys Ala Ala Ala Ile Ser Thr Ser
    370                 375                 380

Arg Val Leu Thr Gln Glu Asp Phe Gln Lys Ile Arg Met Ala Gln Met
385                 390                 395                 400

Arg Lys Glu Leu Asp Ala Ala Pro Gly Lys Xaa Gln Lys Arg Lys Tyr
                405                 410                 415

Ile Glu Ile Asp Ser Asp Glu Glu Pro Arg Gly Glu Leu Leu Ser Leu
            420                 425                 430

Arg Asp Ile Glu Arg Leu His Lys Lys Pro Lys Ser Asp Lys Glu Thr
        435                 440                 445

Arg Leu Ala Thr Ala Met Ala Gly Lys Thr Asp Arg Lys Glu Phe Val
    450                 455                 460

Arg Lys Lys Thr Lys Thr Asn Pro Phe Ser Ser Ser Thr Asn Lys Glu
465                 470                 475                 480

Lys Lys Lys Gln Lys Asn Phe Met Met Met Arg Tyr Ser Gln Asn Val
                485                 490                 495

Arg Ser Lys Asn Lys Arg Ser Phe Arg Glu Lys Gln Leu Ala Leu Arg
            500                 505                 510

Asp Ala Leu Leu Lys Lys Arg Lys Arg Met Lys 
        515                 520



<210> 2309
<211> 339
<212> PRT
<213> Homo sapiens

<400> 2309
Met Lys Glu Glu Glu Gly Phe Pro Glu Asp Glu Ala Thr Glu Ser Glu
  1               5                  10                  15

Lys Asn Phe Lys Phe Gly Lys Arg Val Gly Cys Leu Ser Glu Val Pro
             20                  25                  30

Glu Ser Tyr Val Glu Thr Ser Ala Ser Gly Gly Thr Val Ser Leu Ile
         35                  40                  45

Ala Phe Thr Thr Met Ala Leu Leu Thr Ile Met Glu Phe Ser Val Tyr
     50                  55                  60

Gln Asp Thr Trp Met Lys Tyr Glu Tyr Glu Val Asp Lys Asp Phe Ser
 65                  70                  75                  80

Ser Lys Leu Arg Ile Asn Ile Asp Ile Thr Val Ala Met Lys Cys Gln
                 85                  90                  95

Tyr Val Gly Ala Asp Val Leu Asp Leu Ala Glu Thr Met Val Ala Ser
            100                 105                 110

Ala Asp Gly Leu Val Tyr Glu Pro Thr Val Phe Asp Leu Ser Pro Gln
        115                 120                 125

Gln Lys Glu Trp Gln Arg Met Leu Gln Leu Ile Gln Ser Arg Leu Gln
    130                 135                 140

Glu Glu His Ser Leu Gln Asp Val Ile Phe Lys Ser Ala Phe Lys Ser
145                 150                 155                 160

Thr Ser Thr Ala Leu Pro Pro Arg Glu Asp Asp Ser Ser Gln Ser Pro
                165                 170                 175

Asn Ala Cys Arg Ile His Gly His Leu Tyr Val Asn Lys Val Ala Gly
            180                 185                 190

Asn Phe His Ile Thr Val Gly Lys Ala Ile Pro His Pro Arg Gly His
        195                 200                 205

Ala His Leu Ala Ala Leu Val Asn His Glu Ser Tyr Asn Phe Ser His
    210                 215                 220

Arg Ile Asp His Leu Ser Phe Gly Glu Leu Val Pro Ala Ile Ile Asn
225                 230                 235                 240

Pro Leu Asp Gly Thr Glu Lys Ile Ala Ile Asp His Asn Gln Met Phe
                245                 250                 255

Gln Tyr Phe Ile Thr Val Val Pro Thr Lys Leu His Thr Tyr Lys Ile
            260                 265                 270

Ser Ala Asp Thr His Gln Phe Ser Val Thr Glu Arg Glu Arg Ile Ile
        275                 280                 285

Asn His Ala Ala Gly Ser His Gly Val Ser Gly Ile Phe Met Lys Tyr
    290                 295                 300

Asp Leu Ser Ser Leu Met Val Thr Val Thr Glu Glu His Met Pro Phe
305                 310                 315                 320

Trp Gln Phe Phe Val Arg Leu Cys Gly Ile Val Gly Gly Ile Phe Ser
                325                 330                 335

Thr Thr Gly 




<210> 2310
<211> 194
<212> PRT
<213> Homo sapiens

<400> 2310
Met Ala Ala Ala Ala Pro Asn Ala Gly Gly Ser Ala Pro Glu Thr Ala
  1               5                  10                  15

Gly Ser Ala Glu Ala Pro Leu Gln Tyr Ser Leu Leu Leu Gln Tyr Leu
             20                  25                  30

Val Gly Asp Lys Arg Gln Pro Arg Leu Leu Glu Pro Gly Ser Leu Gly
         35                  40                  45

Gly Ile Pro Ser Pro Ala Lys Ser Glu Glu Gln Lys Met Ile Glu Lys
     50                  55                  60

Ala Met Glu Ser Cys Ala Phe Lys Ala Ala Leu Ala Cys Val Gly Gly
 65                  70                  75                  80

Phe Val Leu Gly Gly Ala Phe Gly Val Phe Thr Ala Gly Ile Asp Thr
                 85                  90                  95

Asn Val Gly Phe Asp Pro Lys Asp Pro Tyr Arg Thr Pro Thr Ala Lys
            100                 105                 110

Glu Val Leu Lys Asp Met Gly Gln Arg Gly Met Ser Tyr Ala Lys Asn
        115                 120                 125

Phe Ala Ile Val Gly Ala Met Phe Ser Cys Thr Glu Cys Leu Ile Glu
    130                 135                 140

Ser Tyr Arg Gly Thr Ser Asp Trp Lys Asn Ser Val Ile Ser Gly Cys
145                 150                 155                 160

Ile Thr Gly Gly Ala Ile Gly Phe Arg Ala Gly Leu Lys Ala Gly Ala
                165                 170                 175

Ile Gly Cys Gly Gly Phe Ala Ala Phe Ser Ala Ala Ile Asp Tyr Tyr
            180                 185                 190

Leu Arg 




<210> 2311
<211> 245
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2311
Met Leu Ala Asn Cys Gly Ser Val Cys Glu Glu Thr Gln Phe Arg Gly
  1               5                  10                  15

Thr Thr Val Ala Pro Ala Leu Xaa Glu Phe Phe Thr Thr Thr Thr Lys
             20                  25                  30

Glu Gly Tyr Asp Arg Arg Pro Val Asp Ile Thr Pro Leu Glu Gln Arg
         35                  40                  45

Lys Leu Thr Phe Asp Thr His Ala Leu Val Gln Asp Leu Glu Thr His
     50                  55                  60

Gly Phe Asp Lys Thr Gln Ala Glu Thr Ile Val Ser Ala Leu Thr Ala
 65                  70                  75                  80

Leu Ser Asn Val Ser Leu Asp Thr Ile Tyr Lys Glu Met Val Thr Gln
                 85                  90                  95

Ala Gln Gln Glu Ile Thr Val Gln Gln Leu Met Ala His Leu Asp Ala
            100                 105                 110

Ile Arg Lys Asp Met Val Ile Leu Glu Lys Ser Glu Phe Ala Asn Leu
        115                 120                 125

Arg Ala Glu Asn Glu Lys Met Lys Ile Glu Leu Asp Gln Val Lys Gln
    130                 135                 140

Gln Leu Met His Glu Thr Ser Arg Ile Arg Ala Asp Asn Lys Leu Asp
145                 150                 155                 160

Ile Asn Leu Glu Arg Ser Arg Val Thr Asp Met Phe Thr Asp Gln Glu
                165                 170                 175

Lys Gln Leu Met Glu Thr Thr Thr Glu Phe Thr Lys Lys Asp Thr Gln
            180                 185                 190

Thr Lys Ser Ile Ile Ser Glu Thr Ser Asn Lys Ile Asp Ala Glu Ile
        195                 200                 205

Ala Ser Leu Lys Thr Leu Met Glu Ser Asn Lys Leu Glu Thr Ile Arg
    210                 215                 220

Tyr Leu Ala Ala Ser Val Phe Thr Cys Leu Ala Ile Ala Leu Gly Phe
225                 230                 235                 240

Tyr Arg Phe Trp Lys 
                245



<210> 2312
<211> 621
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (594)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2312
Met Asn Gly Ser Met Asp Lys Lys Ser Ser Thr Val Ser Glu Asp Val
  1               5                  10                  15

Glu Ala Thr Val Pro Met Leu Gln Arg Thr Lys Ser Arg Ile Glu Gln
             20                  25                  30

Gly Ile Val Asp Arg Ser Glu Thr Gly Val Leu Asp Lys Lys Glu Gly
         35                  40                  45

Glu Gln Ala Lys Ala Leu Phe Glu Lys Val Lys Lys Phe Arg Thr His
     50                  55                  60

Val Glu Glu Gly Asp Ile Val Tyr Arg Leu Tyr Met Arg Gln Thr Ile
 65                  70                  75                  80

Ile Lys Val Ile Lys Phe Ile Leu Ile Ile Cys Tyr Thr Val Tyr Tyr
                 85                  90                  95

Val His Asn Ile Lys Phe Asp Val Asp Cys Thr Val Asp Ile Glu Ser
            100                 105                 110

Leu Thr Gly Tyr Arg Thr Tyr Arg Cys Ala His Pro Leu Ala Thr Leu
        115                 120                 125

Phe Lys Ile Leu Ala Ser Phe Tyr Ile Ser Leu Val Ile Phe Tyr Gly
    130                 135                 140

Leu Ile Cys Met Tyr Thr Leu Trp Trp Met Leu Arg Arg Ser Leu Lys
145                 150                 155                 160

Lys Tyr Ser Phe Glu Ser Ile Arg Glu Glu Ser Ser Tyr Ser Asp Ile
                165                 170                 175

Pro Asp Val Lys Asn Asp Phe Ala Phe Met Leu His Leu Ile Asp Gln
            180                 185                 190

Tyr Asp Pro Leu Tyr Ser Lys Arg Phe Ala Val Phe Leu Ser Glu Val
        195                 200                 205

Ser Glu Asn Lys Leu Arg Gln Leu Asn Leu Asn Asn Glu Trp Thr Leu
    210                 215                 220

Asp Lys Leu Arg Gln Arg Leu Thr Lys Asn Ala Gln Asp Lys Leu Glu
225                 230                 235                 240

Leu His Leu Phe Met Leu Ser Gly Ile Pro Asp Thr Val Phe Asp Leu
                245                 250                 255

Val Glu Leu Glu Val Leu Lys Leu Glu Leu Ile Pro Asp Val Thr Ile
            260                 265                 270

Pro Pro Ser Ile Ala Gln Leu Thr Gly Leu Lys Glu Leu Trp Leu Tyr
        275                 280                 285

His Thr Ala Ala Lys Ile Glu Ala Pro Ala Leu Ala Phe Leu Arg Glu
    290                 295                 300

Asn Leu Arg Ala Leu His Ile Lys Phe Thr Asp Ile Lys Glu Ile Pro
305                 310                 315                 320

Leu Trp Ile Tyr Ser Leu Lys Thr Leu Glu Glu Leu His Leu Thr Gly
                325                 330                 335

Asn Leu Ser Ala Glu Asn Asn Arg Tyr Ile Val Ile Asp Gly Leu Arg
            340                 345                 350

Glu Leu Lys Arg Leu Lys Val Leu Arg Leu Lys Ser Asn Leu Ser Lys
        355                 360                 365

Leu Pro Gln Val Val Thr Asp Val Gly Val His Leu Gln Lys Leu Ser
    370                 375                 380

Ile Asn Asn Glu Gly Thr Lys Leu Ile Val Leu Asn Ser Leu Lys Lys
385                 390                 395                 400

Met Ala Asn Leu Thr Glu Leu Glu Leu Ile Arg Cys Asp Leu Glu Arg
                405                 410                 415

Ile Pro His Ser Ile Phe Ser Leu His Asn Leu Gln Glu Ile Asp Leu
            420                 425                 430

Lys Asp Asn Asn Leu Lys Thr Ile Glu Glu Ile Ile Ser Phe Gln His
        435                 440                 445

Leu His Arg Leu Thr Cys Leu Lys Leu Trp Tyr Asn His Ile Ala Tyr
    450                 455                 460

Ile Pro Ile Gln Ile Gly Asn Leu Thr Asn Leu Glu Arg Leu Tyr Leu
465                 470                 475                 480

Asn Arg Asn Lys Ile Glu Lys Ile Pro Thr Gln Leu Phe Tyr Cys Arg
                485                 490                 495

Lys Leu Arg Tyr Leu Asp Leu Ser His Asn Asn Leu Thr Phe Leu Pro
            500                 505                 510

Ala Asp Ile Gly Leu Leu Gln Asn Leu Gln Asn Leu Ala Ile Thr Ala
        515                 520                 525

Asn Arg Ile Glu Thr Leu Pro Pro Glu Leu Phe Gln Cys Arg Lys Leu
    530                 535                 540

Arg Ala Leu His Leu Gly Asn Asn Val Leu Gln Ser Leu Pro Ser Arg
545                 550                 555                 560

Val Gly Glu Leu Thr Asn Leu Thr Gln Ile Glu Leu Arg Gly Asn Arg
                565                 570                 575

Leu Glu Cys Leu Pro Val Glu Leu Gly Glu Cys Pro Leu Leu Lys Arg
            580                 585                 590

Ser Xaa Leu Val Val Glu Glu Asp Leu Phe Asn Thr Leu Pro Pro Glu
        595                 600                 605

Val Lys Glu Arg Leu Trp Arg Ala Asp Lys Glu Gln Ala 
    610                 615                 620



<210> 2313
<211> 139
<212> PRT
<213> Homo sapiens

<400> 2313
Met Tyr Lys Leu His Leu Tyr Phe Tyr Arg Val Val Met Phe Tyr Met
  1               5                  10                  15

Cys Met Val Gln Glu Lys Ile Gly Ser Asn Gln Ser Ala Val Asp Val
             20                  25                  30

Pro Lys Cys Lys His Arg His Thr His Ala His Thr His Lys His Thr
         35                  40                  45

His Ser Ala Leu Arg Lys Gly Gln Val Ile Ser His Pro Asn Phe Thr
     50                  55                  60

Ser Thr Asp Pro Leu Ala Pro Thr Pro Ala Ser Thr Val Thr Ser Lys
 65                  70                  75                  80

Ala Arg Ala Thr Cys Ala His Gln Thr Cys Ile Lys Gln Leu Ala Gly
                 85                  90                  95

Asp Gly Cys Gly Ala Gly Gly Leu Ser Asp Gly Ser Leu Leu Leu Pro
            100                 105                 110

Leu Leu Arg Val Lys Leu Leu Ser Phe Leu Arg Val Tyr Leu Cys Gln
        115                 120                 125

Val Cys Ala Phe Asn Cys Phe Tyr Phe Val Phe 
    130                 135



<210> 2314
<211> 418
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (318)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2314
Met Pro Leu Pro Val Leu Gln Ala Ile Ser Pro Glu Leu Ser Gly Ala
  1               5                  10                  15

Met Val Val Gly Asp Val Leu Cys Leu Ala Thr Val Leu Thr Ser Leu
             20                  25                  30

Glu Gly Leu Ser Gly Thr Trp Ser Ser Ser Ala Asn Ser Ile Leu His
         35                  40                  45

Ile Asp Pro Lys Thr Gly Val Ala Val Ala Arg Ala Val Gly Ser Val
     50                  55                  60

Thr Val Tyr Tyr Glu Val Ala Gly His Leu Arg Thr Tyr Lys Glu Val
 65                  70                  75                  80

Val Val Ser Val Pro Gln Arg Ile Met Ala Arg His Leu His Pro Ile
                 85                  90                  95

Gln Thr Ser Phe Gln Glu Ala Thr Ala Ser Lys Val Ile Val Ala Val
            100                 105                 110

Gly Asp Arg Ser Ser Asn Leu Arg Gly Glu Cys Thr Pro Thr Gln Arg
        115                 120                 125

Glu Val Ile Gln Ala Leu His Pro Glu Thr Leu Ile Ser Cys Gln Ser
    130                 135                 140

Gln Phe Lys Pro Ala Val Phe Asp Phe Pro Ser Gln Asp Val Phe Thr
145                 150                 155                 160

Val Glu Pro Gln Phe Asp Thr Ala Leu Gly Gln Tyr Phe Cys Ser Ile
                165                 170                 175

Thr Met His Arg Leu Thr Asp Lys Gln Arg Lys His Leu Ser Met Lys
            180                 185                 190

Lys Thr Ala Leu Val Val Ser Ala Ser Leu Ser Ser Ser His Phe Ser
        195                 200                 205

Thr Glu Gln Val Gly Ala Glu Val Pro Phe Ser Pro Gly Leu Phe Ala
    210                 215                 220

Asp Gln Ala Glu Ile Leu Leu Ser Asn His Tyr Thr Ser Ser Glu Ile
225                 230                 235                 240

Arg Val Phe Gly Ala Pro Glu Val Leu Glu Asn Leu Glu Val Lys Ser
                245                 250                 255

Gly Ser Pro Ala Val Leu Ala Phe Ala Lys Glu Lys Ser Phe Gly Trp
            260                 265                 270

Pro Ser Phe Ile Thr Tyr Thr Val Gly Val Leu Asp Pro Ala Ala Gly
        275                 280                 285

Ser Gln Gly Pro Leu Ser Thr Thr Leu Thr Phe Ser Ser Pro Val Thr
    290                 295                 300

Asn Gln Ala Ile Ala Ile Pro Val Thr Val Ala Phe Val Xaa Asp Arg
305                 310                 315                 320

Arg Gly Pro Gly Pro Tyr Gly Ala Ser Leu Phe Gln His Phe Leu Asp
                325                 330                 335

Ser Tyr Gln Val Met Phe Phe Thr Leu Phe Ala Leu Leu Ala Gly Thr
            340                 345                 350

Ala Val Met Ile Ile Ala Tyr His Thr Val Cys Thr Pro Arg Asp Leu
        355                 360                 365

Ala Val Pro Ala Ala Leu Thr Pro Arg Ala Ser Pro Gly His Ser Pro
    370                 375                 380

His Tyr Phe Ala Ala Ser Ser Pro Thr Ser Pro Asn Ala Leu Pro Pro
385                 390                 395                 400

Ala Arg Lys Ala Ser Pro Pro Ser Gly Leu Trp Ser Pro Ala Tyr Ala
                405                 410                 415

Ser His 




<210> 2315
<211> 271
<212> PRT
<213> Homo sapiens

<400> 2315
Met Ile Ala Met Val Glu Gly Ala Gln Arg Arg Lys Thr Pro Asn Glu
  1               5                  10                  15

Ile Ala Leu Thr Ile Leu Leu Ile Ala Leu Thr Ile Val Phe Leu Leu
             20                  25                  30

Ala Thr Ala Thr Leu Trp Pro Phe Ser Ala Trp Gly Gly Asn Ala Val
         35                  40                  45

Ser Val Thr Val Leu Val Ala Leu Leu Val Cys Leu Ile Pro Thr Thr
     50                  55                  60

Ile Gly Gly Leu Leu Ser Ala Ile Gly Val Ala Gly Met Ser Arg Met
 65                  70                  75                  80

Leu Gly Ala Asn Val Ile Ala Thr Ser Gly Arg Ala Val Glu Ala Ala
                 85                  90                  95

Gly Asp Val Asp Val Leu Leu Leu Asp Lys Thr Gly Thr Ile Thr Leu
            100                 105                 110

Gly Asn Arg Gln Ala Ser Glu Phe Ile Pro Ala Gln Gly Val Asp Glu
        115                 120                 125

Lys Thr Leu Ala Asp Ala Ala Gln Leu Ala Ser Leu Ala Asp Glu Thr
    130                 135                 140

Pro Glu Gly Arg Ser Ile Val Ile Leu Ala Lys Gln Arg Phe Asn Leu
145                 150                 155                 160

Arg Glu Arg Asp Val Gln Ser Leu His Ala Thr Phe Val Pro Phe Thr
                165                 170                 175

Ala Gln Ser Arg Met Ser Gly Ile Asn Ile Asp Asn Arg Met Ile Arg
            180                 185                 190

Lys Gly Ser Val Asp Ala Ile Arg Arg His Val Glu Ala Asn Gly Gly
        195                 200                 205

His Phe Pro Thr Asp Val Asp Gln Lys Val Asp Gln Val Ala Arg Gln
    210                 215                 220

Gly Ala Thr Pro Leu Val Val Val Glu Gly Ser Arg Val Leu Gly Val
225                 230                 235                 240

Ile Ala Leu Lys Asp Ile Val Lys Gly Gly Ile Lys Glu Arg Phe Ala
                245                 250                 255

Gln Leu Arg Lys Met Gly Ile Lys Thr Val Met Ile His Arg Arg 
            260                 265                 270



<210> 2316
<211> 111
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2316
Met Phe Trp Pro Met Thr Leu Glu His Gly Trp Gln Leu Pro Ala Glu
  1               5                  10                  15

Val Xaa Leu Pro Ile Pro Gln Gly Thr Xaa Asp Leu Phe Pro Ala Ser
             20                  25                  30

Trp Ser Leu Ser Lys Asn Tyr Leu Arg Asn Leu Trp Val Cys Gly Phe
         35                  40                  45

Thr Gly Leu Ser Val Trp Val Leu Gln Leu Leu Leu Ser Ala Ala Ala
     50                  55                  60

Gly His Ile Phe Pro Leu Thr Gln Pro Phe Met Ala His Gly Glu Leu
 65                  70                  75                  80

Arg Gly Ser Gly Arg Ala Glu Leu Gln Gly Cys Asp Leu Gly Xaa Val
                 85                  90                  95

Gly Leu Arg Cys Pro Ala Gln Gly Ser Gln Val Ala His Gly Leu 
            100                 105                 110



<210> 2317
<211> 397
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (194)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2317
Met Val Arg Pro Gly Ala Arg Leu Cys Leu Gly Ser Val Gly Arg Gly
  1               5                  10                  15

Leu Cys Leu Val Leu Pro Leu Leu Cys Leu Gly Ala Gly Phe Leu Phe
             20                  25                  30

Leu Asn Thr Leu Phe Ile Gln Arg Gly Arg His Glu Thr Thr Trp Thr
         35                  40                  45

Ile Leu Arg Arg Phe Gly Tyr Ser Asp Ala Leu Glu Leu Thr Ala Asp
     50                  55                  60

Tyr Leu Ser Pro Leu Ile His Val Pro Pro Gly Cys Ser Thr Glu Leu
 65                  70                  75                  80

Asn His Leu Gly Tyr Gln Phe Val Gln Arg Val Phe Glu Lys His Asp
                 85                  90                  95

Gln Asp Arg Asp Gly Ala Leu Ser Pro Val Glu Leu Gln Ser Leu Phe
            100                 105                 110

Ser Val Phe Pro Ala Ala Pro Trp Gly Pro Glu Leu Pro Arg Thr Val
        115                 120                 125

Arg Thr Glu Ala Gly Arg Leu Pro Leu His Gly Tyr Leu Cys Gln Trp
    130                 135                 140

Thr Leu Val Thr Tyr Leu Asp Val Arg Ser Cys Leu Gly His Leu Gly
145                 150                 155                 160

Tyr Leu Gly Tyr Pro Thr Leu Cys Glu Gln Asp Gln Ala His Ala Ile
                165                 170                 175

Thr Val Thr Arg Glu Lys Arg Leu Asp Gln Glu Lys Gly Gln Thr Gln
            180                 185                 190

Arg Xaa Val Leu Leu Cys Lys Val Val Gly Ala Arg Gly Val Gly Lys
        195                 200                 205

Ser Ala Phe Leu Gln Ala Phe Leu Gly Arg Gly Leu Gly His Gln Asp
    210                 215                 220

Thr Arg Glu Gln Pro Pro Gly Tyr Ala Ile Asp Thr Val Gln Val Asn
225                 230                 235                 240

Gly Gln Glu Lys Tyr Leu Ile Leu Cys Glu Val Gly Thr Asp Gly Leu
                245                 250                 255

Leu Ala Thr Ser Leu Asp Ala Thr Cys Asp Val Ala Cys Leu Met Phe
            260                 265                 270

Asp Gly Ser Asp Pro Lys Ser Phe Ala His Cys Ala Ser Val Tyr Lys
        275                 280                 285

His His Tyr Met Asp Gly Gln Thr Pro Cys Leu Phe Val Ser Ser Lys
    290                 295                 300

Ala Asp Leu Pro Glu Gly Val Ala Val Ser Gly Pro Ser Pro Ala Glu
305                 310                 315                 320

Phe Cys Arg Lys His Arg Leu Pro Ala Pro Val Pro Phe Ser Cys Ala
                325                 330                 335

Gly Pro Ala Glu Pro Ser Thr Thr Ile Phe Thr Gln Leu Ala Thr Met
            340                 345                 350

Ala Ala Phe Pro His Leu Val His Ala Glu Leu His Pro Ser Ser Phe
        355                 360                 365

Trp Leu Arg Gly Leu Leu Gly Val Val Gly Ala Ala Val Ala Ala Val
    370                 375                 380

Leu Ser Phe Ser Leu Tyr Arg Val Leu Val Lys Ser Gln 
385                 390                 395



<210> 2318
<211> 414
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (286)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (288)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (350)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2318
Met Lys Arg Leu Ser Pro Ala Pro Gln Leu Gly Pro Ser Ser Asp Ala
  1               5                  10                  15

His Thr Ser Tyr Tyr Ser Glu Ser Leu Val His Glu Ser Trp Phe Pro
             20                  25                  30

Pro Arg Ser Ser Leu Glu Glu Leu His Gly Asp Ala Asn Trp Gly Glu
         35                  40                  45

Asp Leu Arg Val Arg Arg Arg Arg Gly Thr Gly Gly Ser Glu Ser Ser
     50                  55                  60

Arg Ala Ser Gly Leu Val Gly Arg Lys Ala Thr Glu Asp Phe Leu Gly
 65                  70                  75                  80

Ser Ser Ser Gly Tyr Ser Ser Glu Asp Asp Tyr Val Gly Tyr Ser Asp
                 85                  90                  95

Val Asp Gln Gln Ser Ser Ser Ser Arg Leu Arg Ser Ala Val Ser Arg
            100                 105                 110

Ala Gly Ser Leu Leu Trp Met Val Ala Thr Ser Pro Gly Arg Leu Phe
        115                 120                 125

Arg Leu Leu Tyr Trp Trp Ala Gly Thr Thr Trp Tyr Arg Leu Thr Thr
    130                 135                 140

Ala Ala Ser Leu Leu Asp Val Phe Val Leu Thr Arg Arg Phe Ser Ser
145                 150                 155                 160

Leu Lys Thr Phe Leu Trp Phe Leu Leu Pro Leu Leu Leu Leu Thr Cys
                165                 170                 175

Leu Thr Tyr Gly Ala Trp Tyr Phe Tyr Pro Tyr Gly Leu Gln Thr Phe
            180                 185                 190

His Pro Ala Leu Val Ser Trp Trp Ala Ala Lys Asp Ser Arg Arg Pro
        195                 200                 205

Asp Glu Gly Trp Glu Ala Arg Asp Ser Ser Pro His Phe Gln Ala Glu
    210                 215                 220

Gln Arg Val Met Ser Arg Val His Ser Leu Glu Arg Arg Leu Glu Ala
225                 230                 235                 240

Leu Ala Ala Glu Phe Ser Ser Asn Trp Gln Lys Glu Ala Met Arg Leu
                245                 250                 255

Glu Arg Leu Glu Leu Arg Gln Gly Ala Pro Gly Gln Gly Gly Gly Gly
            260                 265                 270

Gly Leu Ser His Xaa Asp Thr Leu Ala Leu Leu Glu Gly Xaa Val Xaa
        275                 280                 285

Arg Arg Glu Ala Ala Leu Lys Glu Asp Phe Arg Arg Glu Thr Ala Ala
    290                 295                 300

Arg Ile Gln Val Gly Gly Gly Ile Pro Gln Gly Gly Arg Trp Val Thr
305                 310                 315                 320

Pro Ile Gly Lys Arg Glu Gly Ala Gln Gln Gln Arg Glu Gln Val Ser
                325                 330                 335

Phe Gly Ile Arg Gln Leu Cys His Phe Ala Val Thr Pro Xaa Leu Phe
            340                 345                 350

Phe Ser Phe Phe Phe Phe Phe Leu Arg Gln Tyr Leu Thr Leu Ser Pro
        355                 360                 365

Ser Leu Glu Cys Ser Gly Val Ile Ser Thr His Tyr Asn Leu Cys Leu
    370                 375                 380

Pro Gly Ser Ser Asp Ser Leu Ala Ser Leu Ser Leu Pro Ser Ser Trp
385                 390                 395                 400

Ile Thr Gly Val His His His Ile Gln Leu Ile Leu Tyr Phe 
                405                 410



<210> 2319
<211> 464
<212> PRT
<213> Homo sapiens

<400> 2319
Met Ala Ala Ser Cys Leu Val Leu Leu Ala Leu Cys Leu Leu Leu Pro
  1               5                  10                  15

Leu Leu Leu Leu Gly Gly Trp Lys Arg Trp Arg Arg Gly Arg Ala Ala
             20                  25                  30

Arg His Val Val Ala Val Val Leu Gly Asp Val Gly Arg Ser Pro Arg
         35                  40                  45

Met Gln Tyr His Ala Leu Ser Leu Ala Met His Gly Phe Ser Val Thr
     50                  55                  60

Leu Leu Gly Phe Cys Asn Ser Lys Pro His Asp Glu Leu Leu Gln Asn
 65                  70                  75                  80

Asn Arg Ile Gln Ile Val Gly Leu Thr Glu Leu Gln Ser Leu Ala Val
                 85                  90                  95

Gly Pro Arg Val Phe Gln Tyr Gly Val Lys Val Val Leu Gln Ala Met
            100                 105                 110

Tyr Leu Leu Trp Lys Leu Met Trp Arg Glu Pro Gly Ala Tyr Ile Phe
        115                 120                 125

Leu Gln Asn Pro Pro Gly Leu Pro Ser Ile Ala Val Cys Trp Phe Val
    130                 135                 140

Gly Cys Leu Cys Gly Ser Lys Leu Val Ile Asp Trp His Asn Tyr Gly
145                 150                 155                 160

Tyr Ser Ile Met Gly Leu Val His Gly Pro Asn His Pro Leu Val Leu
                165                 170                 175

Leu Ala Lys Trp Tyr Glu Lys Phe Phe Gly Arg Leu Ser His Leu Asn
            180                 185                 190

Leu Cys Val Thr Asn Ala Met Arg Glu Asp Leu Ala Asp Asn Trp His
        195                 200                 205

Ile Arg Ala Val Thr Val Tyr Asp Lys Pro Ala Ser Phe Phe Lys Glu
    210                 215                 220

Thr Pro Leu Asp Leu Gln His Arg Leu Phe Met Lys Leu Gly Ser Met
225                 230                 235                 240

His Ser Pro Phe Arg Ala Arg Ser Glu Pro Glu Asp Pro Val Thr Glu
                245                 250                 255

Arg Ser Ala Phe Thr Glu Arg Asp Ala Gly Ser Gly Leu Val Thr Arg
            260                 265                 270

Leu Arg Glu Arg Pro Ala Leu Leu Val Ser Ser Thr Ser Trp Thr Glu
        275                 280                 285

Asp Glu Asp Phe Ser Ile Leu Leu Ala Ala Leu Glu Lys Phe Glu Gln
    290                 295                 300

Leu Thr Leu Asp Gly His Asn Leu Pro Ser Leu Val Cys Val Ile Thr
305                 310                 315                 320

Gly Lys Gly Pro Leu Arg Glu Tyr Tyr Ser Arg Leu Ile His Gln Lys
                325                 330                 335

His Phe Gln His Ile Gln Val Cys Thr Pro Trp Leu Glu Ala Glu Asp
            340                 345                 350

Tyr Pro Leu Leu Leu Gly Ser Ala Asp Leu Gly Val Cys Leu His Thr
        355                 360                 365

Ser Ser Ser Gly Leu Asp Leu Pro Met Lys Val Val Asp Met Phe Gly
    370                 375                 380

Cys Cys Leu Pro Val Cys Ala Val Asn Phe Lys Cys Leu His Glu Leu
385                 390                 395                 400

Val Lys His Glu Glu Asn Gly Leu Val Phe Glu Asp Ser Glu Glu Leu
                405                 410                 415

Ala Ala Gln Leu Gln Met Leu Phe Ser Asn Phe Pro Asp Pro Ala Gly
            420                 425                 430

Lys Leu Asn Gln Phe Arg Lys Asn Leu Arg Glu Ser Gln Gln Leu Arg
        435                 440                 445

Trp Asp Glu Ser Trp Val Gln Thr Val Leu Pro Leu Val Met Asp Thr
    450                 455                 460






<210> 2320
<211> 341
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (324)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (327)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (331)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (337)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2320
Met Ser Leu Ser Asp Trp His Leu Ala Val Lys Leu Ala Asp Gln Pro
  1               5                  10                  15

Leu Thr Pro Lys Ser Ile Leu Arg Leu Pro Glu Thr Glu Leu Gly Glu
             20                  25                  30

Tyr Ser Leu Gly Gly Tyr Ser Ile Ser Phe Leu Lys Gln Leu Ile Ala
         35                  40                  45

Gly Lys Leu Gln Glu Ser Val Pro Asp Pro Glu Leu Ile Asp Leu Ile
     50                  55                  60

Tyr Cys Gly Arg Lys Leu Lys Asp Asp Gln Thr Leu Asp Phe Tyr Gly
 65                  70                  75                  80

Ile Gln Pro Gly Ser Thr Val His Val Leu Arg Lys Ser Trp Pro Glu
                 85                  90                  95

Pro Asp Gln Lys Pro Glu Pro Val Asp Lys Val Ala Ala Met Arg Glu
            100                 105                 110

Phe Arg Val Leu His Thr Ala Leu His Ser Ser Ser Ser Tyr Arg Glu
        115                 120                 125

Ala Val Phe Lys Met Leu Ser Asn Lys Glu Ser Leu Asp Gln Ile Ile
    130                 135                 140

Val Ala Thr Pro Gly Leu Ser Ser Asp Pro Ile Ala Leu Gly Val Leu
145                 150                 155                 160

Gln Asp Lys Asp Leu Phe Ser Val Phe Ala Asp Pro Asn Met Leu Asp
                165                 170                 175

Thr Leu Val Pro Ala His Pro Ala Leu Val Asn Ala Ile Val Leu Val
            180                 185                 190

Leu His Ser Val Ala Gly Ser Ala Pro Met Pro Gly Thr Asp Ser Ser
        195                 200                 205

Ser Arg Ser Met Pro Ser Ser Ser Tyr Arg Asp Met Pro Gly Gly Phe
    210                 215                 220

Leu Phe Glu Gly Leu Ser Asp Asp Glu Asp Asp Phe His Pro Asn Thr
225                 230                 235                 240

Arg Ser Thr Pro Ser Ser Ser Thr Pro Ser Ser Arg Pro Ala Ser Leu
                245                 250                 255

Gly Tyr Ser Gly Ala Ala Gly Pro Arg Pro Ile Thr Gln Ser Glu Leu
            260                 265                 270

Ala Thr Ala Leu Ala Leu Ala Ser Thr Pro Glu Ser Ser Ser His Thr
        275                 280                 285

Pro Thr Pro Gly Thr Gln Gly His Ser Ser Gly Thr Ser Pro Met Ser
    290                 295                 300

Ser Gly Val Gln Ser Gly Thr Pro Ile Thr Asn Asp Leu Phe Ser Gln
305                 310                 315                 320

Ala Leu Gln Xaa Ala Leu Xaa Ala Ser Gly Xaa Pro Lys Leu Lys Ala
                325                 330                 335

Xaa Ala Ala Ser Cys 
            340



<210> 2321
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2321
Met His Thr Gly Ala Asp Thr Pro Gln Leu Pro Cys Thr Arg Leu Val
  1               5                  10                  15

Gln Ala Pro Pro Arg Cys Thr Val Arg Thr Ala Gly His Val Pro Val
             20                  25                  30

Xaa Ala Met Gly Leu Xaa Arg Trp Ala Ser Lys Val Leu Gly Ala Ala
         35                  40                  45

Gly Cys Met Xaa Ala Leu Leu Ala Gly Val Ser Ala Arg Xaa Lys Ser
     50                  55                  60

Leu Glu Ala Gly Phe Pro Glu Ala Arg Ser Leu Ala Cys Thr Thr Arg
 65                  70                  75                  80

Pro Pro Leu Leu Ala Ser Arg His Gln Ala Ser Ser Gly His Gly Gly
                 85                  90                  95

Arg Asp Gly Pro Arg Asn Cys Cys Phe Leu Arg Ile Leu Ser Ala Gly
            100                 105                 110

Asn Met Ala Gly Glu Gln Ser Leu Val Pro Leu Pro Trp Pro Leu Leu
        115                 120                 125

Gly Gln Pro Val Leu Pro Glu Pro Leu Ser Gln Arg Ala Arg Trp Pro
    130                 135                 140

Trp Leu Val Gly Val Asp Val Gly Val Ser His Leu Asp Gln Thr Gly
145                 150                 155                 160

Val Gly Glu Leu His Thr Leu Pro Gly Asn Gly Met Arg Val Gly Pro
                165                 170                 175

Gly Gln Gly Gln Leu Leu Gly Glu Arg His Trp Gly Leu Glu Ala Gly
            180                 185                 190

Ser Gly Trp Cys Val Ser Pro Val Tyr Phe 
        195                 200



<210> 2322
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (138)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2322
Met Asp Arg Pro Tyr Gln Phe Tyr Tyr Phe Val Pro Leu Val Thr Val
  1               5                  10                  15

Trp Phe Met Val Ile Tyr Val Thr Leu Ala Leu Trp Pro Gln Ile Ile
             20                  25                  30

Gln Lys Lys Ala Asn Gly Asn Cys Phe Trp His Phe Gly Leu Leu Leu
         35                  40                  45

Lys Leu Gly Phe Leu Leu Leu Phe Ile Cys Phe Leu Ala Tyr Ser Gln
     50                  55                  60

Gly Ala Phe Glu Lys Ile Phe Ser Leu Trp Pro Leu Ser Lys Cys Phe
 65                  70                  75                  80

Glu Leu Lys Gly Asn Val Tyr Glu Trp Trp Phe Arg Trp Arg Leu Asp
                 85                  90                  95

Arg Tyr Val Ser Phe Pro Arg Asn Ala Val Cys Phe Tyr Xaa Ser Gly
            100                 105                 110

Phe Cys Arg Asn Arg Lys Tyr Phe Leu Lys Glu Lys Gly Glu Pro Leu
        115                 120                 125

Phe Phe Lys Gln Lys Phe Gln Asn Phe Xaa 
    130                 135



<210> 2323
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (31)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (41)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2323
Met Ile Pro Ala Glu Ser Arg Ser Phe Leu Leu Thr Asp Leu Ala Ser
  1               5                  10                  15

Gly Arg Thr Tyr Asp Leu Cys Val Leu Ala Val Tyr Glu Asp Xaa Ala
             20                  25                  30

Thr Gly Leu Thr Ala Thr Arg Xaa Xaa Xaa Cys Ala Arg Phe Ser Thr
         35                  40                  45

Glu Pro Ala Leu Arg Pro Cys Gly Ala Pro His Ala Pro Phe Leu Gly
     50                  55                  60

Gly Thr Met Ile Ile Ala Leu Gly Gly Val Ile Val Ala Ser Val Leu
 65                  70                  75                  80

Val Phe Ile Phe Val Leu Leu Met Arg Tyr Lys Val His Gly Gly Gln
                 85                  90                  95

Pro Pro Gly Lys Ala Lys Ile Pro Ala Pro Val Ser Ser Val Cys Ser
            100                 105                 110

Gln Thr Asn Gly Ala Leu Gly Pro Thr Pro Thr Pro Ala Pro Pro Ala
        115                 120                 125

Pro Glu Pro Ala Ala Leu Arg Ala His Thr Val Val Gln Leu Asp Cys
    130                 135                 140

Glu Pro Trp Gly Pro Gly His Glu Pro Val Gly Pro 
145                 150                 155



<210> 2324
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2324
Met Asp Asn Val Val Leu Asp Leu Asp Leu Leu Gln Cys Gly Ser Ala
  1               5                  10                  15

Gly Pro Glu Ala Ser Cys Cys Pro Gly Trp Leu Pro Arg Cys Leu His
             20                  25                  30

Pro Leu Ser Leu Gly Gln Leu Cys Phe Leu Pro Leu Cys Ser Gly Pro
         35                  40                  45

Gly Trp Leu Leu Ala Cys Arg Trp Asn Cys Phe Phe Asn Met Gly Arg
     50                  55                  60

Tyr Ile Tyr Phe Phe Pro Cys Gly Trp Val Ser Leu Phe Gly Phe Ser
 65                  70                  75                  80

Ser Val Phe Thr Phe Leu Phe Leu Glu Gly Trp Glu Arg Ile Lys Leu
                 85                  90                  95

Leu Trp Pro Pro Val Ser Gln Gln Gln Val Lys Trp Ser Cys Ser Gly
            100                 105                 110

Cys Pro Leu Leu Arg Thr Lys Ser Xaa Asn Val Gln Arg 
        115                 120                 125



<210> 2325
<211> 511
<212> PRT
<213> Homo sapiens

<400> 2325
Met Val Lys Ile Leu Val Val Thr Val Gln Leu Ile Leu Phe Gly Leu
  1               5                  10                  15

Ser Asn Gln Leu Ala Val Thr Phe Arg Glu Glu Asn Thr Ile Ala Phe
             20                  25                  30

Arg His Leu Phe Leu Leu Gly Tyr Ser Asp Gly Ala Asp Asp Thr Phe
         35                  40                  45

Ala Ala Tyr Thr Arg Glu Gln Leu Tyr Gln Ala Ile Phe His Ala Val
     50                  55                  60

Asp Gln Tyr Leu Ala Leu Pro Asp Val Ser Leu Gly Arg Tyr Ala Tyr
 65                  70                  75                  80

Val Arg Gly Gly Gly Asp Pro Trp Thr Asn Gly Ser Gly Leu Ala Leu
                 85                  90                  95

Cys Gln Arg Tyr Tyr His Arg Gly His Val Asp Pro Ala Asn Asp Thr
            100                 105                 110

Phe Asp Ile Asp Pro Met Val Val Thr Asp Cys Ile Gln Val Asp Pro
        115                 120                 125

Pro Glu Arg Pro Pro Pro Pro Pro Ser Asp Asp Leu Thr Leu Leu Glu
    130                 135                 140

Ser Ser Ser Ser Tyr Lys Asn Leu Thr Leu Lys Phe His Lys Leu Val
145                 150                 155                 160

Asn Val Thr Ile His Phe Arg Leu Lys Thr Ile Asn Leu Gln Ser Leu
                165                 170                 175

Ile Asn Asn Glu Ile Pro Asp Cys Tyr Thr Phe Ser Val Leu Ile Thr
            180                 185                 190

Phe Asp Asn Lys Ala His Ser Gly Arg Ile Pro Ile Ser Leu Glu Thr
        195                 200                 205

Gln Ala His Ile Gln Glu Cys Lys His Pro Ser Val Phe Gln His Gly
    210                 215                 220

Asp Asn Ser Phe Arg Leu Leu Phe Asp Val Val Val Ile Leu Thr Cys
225                 230                 235                 240

Ser Leu Ser Phe Leu Leu Cys Ala Arg Ser Leu Leu Arg Gly Phe Leu
                245                 250                 255

Leu Gln Asn Glu Phe Val Gly Phe Met Trp Arg Gln Arg Gly Arg Val
            260                 265                 270

Ile Ser Leu Trp Glu Arg Leu Glu Phe Val Asn Gly Trp Tyr Ile Leu
        275                 280                 285

Leu Val Thr Ser Asp Val Leu Thr Ile Ser Gly Thr Ile Met Lys Ile
    290                 295                 300

Gly Ile Glu Ala Lys Asn Leu Ala Ser Tyr Asp Val Cys Ser Ile Leu
305                 310                 315                 320

Leu Gly Thr Ser Thr Leu Leu Val Trp Val Gly Val Ile Arg Tyr Leu
                325                 330                 335

Thr Phe Phe His Asn Tyr Asn Ile Leu Ile Ala Thr Leu Arg Val Ala
            340                 345                 350

Leu Pro Ser Val Met Arg Phe Cys Cys Cys Val Ala Val Ile Tyr Leu
        355                 360                 365

Gly Tyr Cys Phe Cys Gly Trp Ile Val Leu Gly Pro Tyr His Val Lys
    370                 375                 380

Phe Arg Ser Leu Ser Met Val Ser Glu Cys Leu Phe Ser Leu Ile Asn
385                 390                 395                 400

Gly Asp Asp Met Phe Val Thr Phe Ala Ala Met Gln Ala Gln Gln Gly
                405                 410                 415

Arg Ser Ser Leu Val Trp Leu Phe Ser Gln Leu Tyr Leu Tyr Ser Phe
            420                 425                 430

Ile Ser Leu Phe Ile Tyr Met Val Leu Ser Leu Phe Ile Ala Leu Ile
        435                 440                 445

Thr Gly Ala Tyr Asp Thr Ile Lys His Pro Gly Gly Ala Gly Ala Glu
    450                 455                 460

Glu Ser Glu Leu Gln Ala Tyr Ile Ala Gln Cys Gln Asp Ser Pro Thr
465                 470                 475                 480

Ser Gly Lys Phe Arg Arg Gly Ser Gly Ser Ala Cys Ser Leu Leu Cys
                485                 490                 495

Cys Cys Gly Arg Asp Pro Ser Glu Glu His Ser Leu Leu Val Asn 
            500                 505                 510



<210> 2326
<211> 205
<212> PRT
<213> Homo sapiens

<400> 2326
Met Pro Tyr Gly Trp Leu Thr Glu Ile Arg Ala Val Tyr Pro Ala Phe
  1               5                  10                  15

Asp Lys Asn Asn Pro Ser Asn Lys Leu Val Ser Thr Ser Asn Thr Val
             20                  25                  30

Thr Ala Ala His Ile Lys Lys Phe Thr Phe Val Cys Met Ala Leu Ser
         35                  40                  45

Leu Thr Leu Cys Phe Val Met Phe Trp Thr Pro Asn Val Ser Glu Lys
     50                  55                  60

Ile Leu Ile Asp Ile Ile Gly Val Asp Phe Ala Phe Ala Glu Leu Cys
 65                  70                  75                  80

Val Val Pro Leu Arg Ile Phe Ser Phe Phe Pro Val Pro Val Thr Val
                 85                  90                  95

Arg Ala His Leu Thr Gly Trp Leu Met Thr Leu Lys Lys Thr Phe Val
            100                 105                 110

Leu Ala Pro Ser Ser Val Leu Arg Ile Ile Val Leu Ile Ala Ser Leu
        115                 120                 125

Val Val Leu Pro Tyr Leu Gly Val His Gly Ala Thr Leu Gly Val Gly
    130                 135                 140

Ser Leu Leu Ala Gly Phe Val Gly Glu Ser Thr Met Val Ala Ile Ala
145                 150                 155                 160

Ala Cys Tyr Val Tyr Arg Lys Gln Lys Lys Lys Met Glu Asn Glu Ser
                165                 170                 175

Ala Thr Glu Gly Glu Asp Ser Ala Met Thr Asp Met Pro Pro Thr Glu
            180                 185                 190

Glu Val Thr Asp Ile Val Glu Met Arg Glu Glu Asn Glu 
        195                 200                 205



<210> 2327
<211> 552
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (145)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2327
Met Leu Asp His Lys Asp Leu Glu Ala Glu Ile His Pro Leu Lys Asn
  1               5                  10                  15

Glu Glu Arg Lys Ser Gln Glu Asn Leu Gly Asn Pro Ser Lys Asn Glu
             20                  25                  30

Asp Asn Val Lys Ser Ala Pro Pro Gln Ser Arg Leu Ser Arg Cys Arg
         35                  40                  45

Ala Ala Ala Phe Phe Leu Ser Leu Phe Leu Cys Leu Phe Val Val Phe
     50                  55                  60

Val Val Ser Phe Val Ile Pro Cys Pro Asp Arg Pro Ala Ser Gln Arg
 65                  70                  75                  80

Met Trp Arg Ile Asp Tyr Ser Ala Ala Val Ile Tyr Asp Phe Leu Ala
                 85                  90                  95

Val Asp Asp Ile Asn Gly Asp Arg Ile Gln Asp Val Leu Phe Leu Tyr
            100                 105                 110

Lys Asn Thr Asn Ser Ser Asn Asn Phe Ser Arg Ser Cys Val Asp Glu
        115                 120                 125

Gly Phe Ser Ser Pro Cys Thr Phe Ala Ala Ala Val Ser Gly Ala Asn
    130                 135                 140

Xaa Ser Thr Leu Trp Glu Xaa Pro Val Ala Gln Asp Val Ala Leu Val
145                 150                 155                 160

Glu Cys Ala Val Pro Gln Pro Arg Gly Ser Glu Ala Pro Ser Ala Cys
                165                 170                 175

Ile Leu Val Gly Arg Pro Ser Ser Phe Ile Ala Val Asn Leu Phe Thr
            180                 185                 190

Gly Glu Thr Leu Trp Asn His Ser Ser Ser Phe Ser Gly Asn Ala Ser
        195                 200                 205

Ile Leu Ser Pro Leu Leu Gln Val Pro Asp Val Asp Gly Asp Gly Ala
    210                 215                 220

Pro Asp Leu Leu Val Leu Thr Gln Glu Arg Glu Glu Val Ser Gly His
225                 230                 235                 240

Leu Tyr Ser Gly Ser Thr Gly His Gln Ile Gly Leu Arg Gly Ser Leu
                245                 250                 255

Gly Val Asp Gly Glu Ser Gly Phe Leu Leu His Val Thr Arg Thr Gly
            260                 265                 270

Ala His Tyr Ile Leu Phe Pro Cys Ala Ser Ser Leu Cys Gly Cys Ser
        275                 280                 285

Val Lys Gly Leu Tyr Glu Lys Val Thr Gly Ser Gly Gly Pro Phe Lys
    290                 295                 300

Ser Asp Pro His Trp Glu Ser Met Leu Asn Ala Thr Thr Arg Arg Met
305                 310                 315                 320

Leu Ser His Ser Ser Gly Ala Val Arg Tyr Leu Met His Val Pro Gly
                325                 330                 335

Asn Ala Gly Ala Asp Val Leu Leu Val Gly Ser Glu Ala Phe Val Leu
            340                 345                 350

Leu Asp Gly Gln Glu Leu Thr Pro Arg Trp Thr Pro Lys Ala Ala His
        355                 360                 365

Val Leu Arg Lys Pro Ile Phe Gly Arg Tyr Lys Pro Asp Thr Leu Ala
    370                 375                 380

Val Ala Val Glu Asn Gly Thr Gly Thr Asp Arg Gln Ile Leu Phe Leu
385                 390                 395                 400

Asp Leu Gly Thr Gly Ala Val Leu Cys Ser Leu Ala Leu Pro Ser Leu
                405                 410                 415

Pro Gly Gly Pro Leu Ser Ala Ser Leu Pro Thr Ala Asp His Arg Ser
            420                 425                 430

Ala Phe Phe Phe Trp Gly Leu His Glu Leu Gly Ser Thr Ser Glu Thr
        435                 440                 445

Glu Thr Gly Glu Ala Arg His Ser Leu Tyr Met Phe His Pro Thr Leu
    450                 455                 460

Pro Arg Val Leu Leu Glu Leu Ala Asn Val Ser Thr His Ile Val Ala
465                 470                 475                 480

Phe Asp Ala Val Leu Phe Glu Pro Ser Arg His Ala Ala Tyr Ile Leu
                485                 490                 495

Leu Thr Gly Pro Ala Asp Ser Glu Ala Pro Gly Leu Val Ser Val Ile
            500                 505                 510

Lys His Lys Val Arg Asp Leu Val Pro Ser Ser Arg Val Val Arg Leu
        515                 520                 525

Gly Glu Gly Gly Pro Asp Ser Asp Gln Ala Ile Arg Asp Arg Phe Ser
    530                 535                 540

Arg Leu Arg Tyr Gln Ser Glu Ala 
545                 550



<210> 2328
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2328
Met Lys Thr Pro Ala Phe Pro Asp Ser Pro Pro Ser Ser Val Leu Gln
  1               5                  10                  15

Phe Ser Glu Lys Ser Trp Asp Met Trp Glu Gly Ala Trp Glu Leu Gly
             20                  25                  30

Ser Leu Arg Leu Pro Gly Arg Gln Phe Arg Leu Cys Arg Lys Glu Gln
         35                  40                  45

Ser Pro Trp Glu Ala Leu Gly Glu Gly Gly Ala Xaa Gly Pro Ala Arg
     50                  55                  60

Met Val Leu Pro Ala Thr Gly Gly Leu Arg Val Val Ser Ala Pro Cys
 65                  70                  75                  80

Ile Ser Pro Ser Leu Leu Thr Phe Leu Leu Cys Phe Pro Pro Ser Val
                 85                  90                  95

Cys Gln Arg Gly Gly Thr Gly Asn Arg Thr Ala Val Ala Ala Leu Ser
            100                 105                 110

Leu Leu Ser Thr Val Tyr Ser Gly Leu Ser Gly Asp Ser Arg Glu Pro
        115                 120                 125

Gly His Leu Ala Ala Val Arg Pro Leu Asn Leu 
    130                 135



<210> 2329
<211> 300
<212> PRT
<213> Homo sapiens

<400> 2329
Met Lys Phe Leu Leu Asp Ile Leu Leu Leu Leu Pro Leu Leu Ile Val
  1               5                  10                  15

Cys Ser Leu Glu Ser Phe Val Lys Leu Phe Ile Pro Lys Arg Arg Lys
             20                  25                  30

Ser Val Thr Gly Glu Ile Val Leu Ile Thr Gly Ala Gly His Gly Ile
         35                  40                  45

Gly Arg Leu Thr Ala Tyr Glu Phe Ala Lys Leu Lys Ser Lys Leu Val
     50                  55                  60

Leu Trp Asp Ile Asn Lys His Gly Leu Glu Glu Thr Ala Ala Lys Cys
 65                  70                  75                  80

Lys Gly Leu Gly Ala Lys Val His Thr Phe Val Val Asp Cys Ser Asn
                 85                  90                  95

Arg Glu Asp Ile Tyr Ser Ser Ala Lys Lys Val Lys Ala Glu Ile Gly
            100                 105                 110

Asp Val Ser Ile Leu Val Asn Asn Ala Gly Val Val Tyr Thr Ser Asp
        115                 120                 125

Leu Phe Ala Thr Gln Asp Pro Gln Ile Glu Lys Thr Phe Glu Val Asn
    130                 135                 140

Val Leu Ala His Phe Trp Thr Thr Lys Ala Phe Leu Pro Ala Met Thr
145                 150                 155                 160

Lys Asn Asn His Gly His Ile Val Thr Val Ala Ser Ala Ala Gly His
                165                 170                 175

Val Ser Val Pro Phe Leu Leu Ala Tyr Cys Ser Ser Lys Phe Ala Ala
            180                 185                 190

Val Gly Phe His Lys Thr Leu Thr Asp Glu Leu Ala Ala Leu Gln Ile
        195                 200                 205

Thr Gly Val Lys Thr Thr Cys Leu Cys Pro Asn Phe Val Asn Thr Gly
    210                 215                 220

Phe Ile Lys Asn Pro Ser Thr Ser Leu Gly Pro Thr Leu Glu Pro Glu
225                 230                 235                 240

Glu Val Val Asn Arg Leu Met His Gly Ile Leu Thr Glu Gln Lys Met
                245                 250                 255

Ile Phe Ile Pro Ser Ser Ile Ala Phe Leu Thr Thr Leu Glu Arg Ile
            260                 265                 270

Leu Pro Glu Arg Phe Leu Ala Val Leu Lys Arg Lys Ile Ser Val Lys
        275                 280                 285

Phe Asp Ala Val Ile Gly Tyr Lys Met Lys Ala Gln 
    290                 295                 300



<210> 2330
<211> 142
<212> PRT
<213> Homo sapiens

<400> 2330
Met Ala Ala Ala Val Ala Ala Ala Gly Ala Gly Glu Pro Gln Ser Pro
  1               5                  10                  15

Asp Glu Leu Leu Pro Lys Gly Asp Ala Glu Lys Pro Glu Glu Glu Leu
             20                  25                  30

Glu Glu Asp Asp Asp Glu Glu Leu Asp Glu Thr Leu Ser Glu Arg Leu
         35                  40                  45

Trp Gly Leu Thr Glu Met Phe Pro Glu Arg Val Arg Ser Ala Ala Gly
     50                  55                  60

Ala Thr Phe Asp Leu Ser Leu Phe Val Ala Gln Lys Met Tyr Arg Phe
 65                  70                  75                  80

Ser Arg Ala Ala Leu Trp Ile Gly Thr Thr Ser Phe Met Ile Leu Val
                 85                  90                  95

Leu Pro Val Val Phe Glu Thr Glu Lys Leu Gln Met Glu Gln Gln Gln
            100                 105                 110

Gln Leu Gln Gln Arg Gln Ile Leu Leu Gly Pro Asn Thr Gly Leu Ser
        115                 120                 125

Gly Gly Met Pro Gly Ala Leu Pro Ser Leu Pro Gly Lys Ile 
    130                 135                 140



<210> 2331
<211> 273
<212> PRT
<213> Homo sapiens

<400> 2331
Met Val Leu Gly Thr Gly Leu Arg Cys Ile Pro Ile Ser Asp Leu Ile
  1               5                  10                  15

Leu Lys Arg Arg Leu Ile His Gly Gly Gln Met Leu Asn Gly Leu Ala
             20                  25                  30

Gly Pro Thr Val Met Asn Ala Ala Pro Phe Leu Ser Thr Thr Trp Phe
         35                  40                  45

Ser Ala Asp Glu Arg Ala Thr Ala Thr Ala Ile Ala Ser Met Leu Ser
     50                  55                  60

Tyr Leu Gly Gly Ala Cys Ala Phe Leu Val Gly Pro Leu Val Val Pro
 65                  70                  75                  80

Ala Pro Asn Gly Thr Ser Pro Leu Leu Ala Ala Glu Ser Ser Arg Ala
                 85                  90                  95

His Ile Lys Asp Arg Ile Glu Ala Val Leu Tyr Ala Glu Phe Gly Val
            100                 105                 110

Val Cys Leu Ile Phe Ser Ala Thr Leu Ala Tyr Phe Pro Pro Arg Pro
        115                 120                 125

Pro Leu Pro Pro Ser Val Ala Ala Ala Ser Gln Arg Leu Ser Tyr Arg
    130                 135                 140

Arg Ser Val Cys Arg Leu Leu Ser Asn Phe Arg Phe Leu Met Ile Ala
145                 150                 155                 160

Leu Ala Tyr Ala Ile Pro Leu Gly Val Phe Ala Gly Trp Ser Gly Val
                165                 170                 175

Leu Asp Leu Ile Leu Thr Pro Ala His Val Ser Gln Val Asp Ala Gly
            180                 185                 190

Trp Ile Gly Phe Trp Ser Ile Val Gly Gly Cys Val Val Gly Ile Ala
        195                 200                 205

Met Ala Arg Phe Ala Asp Phe Ile Arg Gly Met Leu Lys Leu Ile Leu
    210                 215                 220

Leu Leu Leu Phe Ser Gly Ala Thr Leu Ser Ser Thr Trp Phe Thr Leu
225                 230                 235                 240

Thr Cys Leu Asn Ser Ile Thr His Leu Pro Leu Thr Thr Val Thr Leu
                245                 250                 255

Tyr Ala Ser Cys Ile Leu Leu Gly Val Phe Leu Asn Ser Ser Val Pro
            260                 265                 270

Ile 




<210> 2332
<211> 344
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (318)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (319)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (321)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (341)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2332
Met Ala Ser Ser Ala Ala Gly Cys Val Val Ile Val Gly Ser Gly Val
  1               5                  10                  15

Ile Gly Arg Ser Trp Ala Met Leu Phe Ala Ser Gly Gly Phe Gln Val
             20                  25                  30

Lys Leu Tyr Asp Ile Glu Gln Gln Gln Ile Arg Asn Ala Leu Glu Asn
         35                  40                  45

Ile Arg Lys Glu Met Lys Leu Leu Glu Gln Ala Gly Ser Leu Lys Gly
     50                  55                  60

Ser Leu Ser Val Glu Glu Gln Leu Ser Leu Ile Ser Gly Cys Pro Asn
 65                  70                  75                  80

Ile Gln Glu Ala Val Glu Gly Ala Met His Ile Gln Glu Cys Val Pro
                 85                  90                  95

Glu Asp Leu Glu Leu Lys Lys Lys Ile Phe Ala Gln Leu Asp Ser Ile
            100                 105                 110

Ile Asp Asp Arg Val Ile Leu Ser Ser Ser Thr Ser Cys Leu Met Pro
        115                 120                 125

Ser Lys Leu Phe Ala Gly Leu Val His Val Lys Gln Cys Ile Val Ala
    130                 135                 140

His Pro Val Asn Pro Pro Tyr Tyr Ile Pro Leu Val Glu Leu Val Pro
145                 150                 155                 160

His Pro Glu Thr Ala Pro Thr Thr Val Asp Arg Thr His Ala Leu Met
                165                 170                 175

Lys Lys Ile Gly Gln Cys Pro Met Arg Val Gln Lys Glu Val Ala Gly
            180                 185                 190

Phe Val Leu Asn Arg Leu Gln Tyr Ala Ile Ile Ser Glu Ala Trp Arg
        195                 200                 205

Leu Val Glu Glu Gly Ile Val Ser Pro Ser Asp Leu Asp Leu Val Met
    210                 215                 220

Ser Glu Gly Leu Gly Met Arg Tyr Ala Phe Ile Gly Pro Leu Glu Thr
225                 230                 235                 240

Met His Leu Asn Ala Glu Gly Met Leu Ser Tyr Cys Asp Arg Tyr Ser
                245                 250                 255

Glu Gly Ile Lys His Val Leu Gln Thr Phe Gly Pro Ile Pro Glu Phe
            260                 265                 270

Ser Arg Ala Thr Ala Glu Lys Val Asn Gln Asp Met Cys Met Lys Val
        275                 280                 285

Pro Asp Asp Pro Glu His Leu Ala Ala Arg Arg Gln Trp Arg Asp Glu
    290                 295                 300

Cys Leu Met Arg Leu Ala Lys Leu Lys Ser Gln Val Gln Xaa Xaa Trp
305                 310                 315                 320

Xaa Phe Pro Pro Phe Leu Phe Ser Leu Ile Ala Phe Asp Tyr Ile Leu
                325                 330                 335

Gln Pro Val Ile Xaa Val Ser Trp 
            340



<210> 2333
<211> 152
<212> PRT
<213> Homo sapiens

<400> 2333
Met Asp Asn Val Gln Pro Lys Ile Lys His Arg Pro Phe Cys Phe Ser
  1               5                  10                  15

Val Lys Gly His Val Lys Met Leu Arg Leu Ala Leu Thr Val Thr Ser
             20                  25                  30

Met Thr Phe Phe Ile Ile Ala Gln Ala Pro Glu Pro Tyr Ile Val Ile
         35                  40                  45

Thr Gly Phe Glu Val Thr Val Ile Leu Phe Phe Ile Leu Leu Tyr Val
     50                  55                  60

Leu Arg Leu Asp Arg Leu Met Lys Trp Leu Phe Trp Pro Leu Leu Asp
 65                  70                  75                  80

Ile Ile Asn Ser Leu Val Thr Thr Val Phe Met Leu Ile Val Ser Val
                 85                  90                  95

Leu Ala Leu Ile Pro Glu Thr Thr Thr Leu Thr Val Gly Gly Gly Val
            100                 105                 110

Phe Ala Leu Val Thr Ala Val Cys Cys Leu Ala Asp Gly Ala Leu Ile
        115                 120                 125

Tyr Arg Lys Leu Leu Phe Asn Pro Ser Gly Pro Tyr Gln Lys Lys Pro
    130                 135                 140

Val His Glu Lys Lys Glu Val Leu 
145                 150



<210> 2334
<211> 277
<212> PRT
<213> Homo sapiens

<400> 2334
Met Ser Cys Pro Val Gln Thr Met Asp Pro Glu Val Thr Leu Leu Leu
  1               5                  10                  15

Gln Cys Pro Gly Gly Gly Leu Pro Gln Glu Gln Ile Gln Ala Glu Leu
             20                  25                  30

Ser Pro Ala His Asp Arg Arg Pro Leu Pro Gly Gly Asp Glu Ala Ile
         35                  40                  45

Thr Ala Ile Trp Glu Thr Arg Leu Lys Ala Gln Pro Trp Leu Phe Asp
     50                  55                  60

Ala Pro Lys Phe Arg Leu His Ser Ala Thr Leu Ala Pro Ile Gly Ser
 65                  70                  75                  80

Arg Gly Pro Gln Leu Leu Leu Arg Leu Gly Leu Thr Ser Tyr Arg Asp
                 85                  90                  95

Phe Leu Gly Thr Asn Trp Ser Ser Ser Ala Ala Trp Leu Arg Gln Gln
            100                 105                 110

Gly Ala Thr Asp Trp Gly Asp Thr Gln Ala Tyr Leu Ala Asp Pro Leu
        115                 120                 125

Gly Val Gly Ala Ala Leu Ala Thr Ala Asp Asp Phe Leu Val Phe Leu
    130                 135                 140

Arg Arg Ser Arg Gln Val Ala Glu Ala Pro Gly Leu Val Asp Val Pro
145                 150                 155                 160

Gly Gly His Pro Glu Pro Gln Val Asn Leu Pro Leu Leu Thr Leu Ser
                165                 170                 175

Gln Pro Leu Leu Leu Gly Ile Ala Arg Asn Glu Thr Ser Ala Gly Arg
            180                 185                 190

Ala Ser Ala Glu Phe Tyr Val Gln Cys Ser Leu Thr Ser Glu Gln Val
        195                 200                 205

Arg Lys His Tyr Leu Ser Gly Gly Pro Glu Ala His Glu Ser Thr Gly
    210                 215                 220

Ile Phe Phe Val Glu Thr Gln Asn Val Arg Arg Leu Pro Glu Thr Glu
225                 230                 235                 240

Met Trp Ala Glu Leu Cys Pro Ser Ala Lys Gly Ala Ile Ile Leu Tyr
                245                 250                 255

Asn Arg Val Gln Gly Ser Pro Thr Gly Ala Ala Leu Gly Ser Pro Ala
            260                 265                 270

Leu Leu Pro Pro Leu 
        275



<210> 2335
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2335
Met Gln Pro Pro Ala Leu Arg Thr Met Val Ala Leu Ala Thr Trp Gly
  1               5                  10                  15

Met Leu Lys Leu Ser Gly Arg Gln Trp Ser Gly Trp Asp Val Trp Ile
             20                  25                  30

Cys Cys Leu Ala Ala Ile Leu Leu Met Asp Pro Val Ala Ile Leu Ser
         35                  40                  45

Gln Ser Leu Trp Leu Ser Ala Ala Ala Val Ala Ala Leu Ile Phe Trp
     50                  55                  60

Tyr Gln Trp Phe Pro Cys Pro Glu Trp Gln Leu Pro Pro Val Leu Arg
 65                  70                  75                  80

Ala Xaa Val Ser Leu Ile His Leu Gln Leu Gly Ile Thr Leu Leu Leu
                 85                  90                  95

Met Pro Val Gln Ile Val Ile Phe Xaa Gly Ile Ser Leu Thr Ser Phe
            100                 105                 110

Ile Ala Asn Leu Leu Ala Ile Pro Leu Val Thr Phe Ile Thr Val Pro
        115                 120                 125

Leu Ile Leu Ala Ala Met Val Val His Leu Ser Gly Pro Leu Ile Leu
    130                 135                 140

Glu Gln Gly Leu Trp Phe Leu Ala Asp Arg Ser Leu Ala Leu Leu Phe
145                 150                 155                 160

Trp Gly Leu Lys Ser Leu 
                165



<210> 2336
<211> 138
<212> PRT
<213> Homo sapiens

<400> 2336
Met Ile Ser Leu Thr Asp Thr Gln Lys Ile Gly Met Gly Leu Thr Gly
  1               5                  10                  15

Phe Gly Val Phe Phe Leu Phe Phe Gly Met Ile Leu Phe Phe Asp Lys
             20                  25                  30

Ala Leu Leu Ala Ile Gly Asn Val Leu Phe Val Ala Gly Leu Ala Phe
         35                  40                  45

Val Ile Gly Leu Glu Arg Thr Phe Arg Phe Phe Phe Gln Lys His Lys
     50                  55                  60

Met Lys Ala Thr Gly Phe Phe Leu Gly Gly Val Phe Val Val Leu Ile
 65                  70                  75                  80

Gly Trp Pro Leu Ile Gly Met Ile Phe Glu Ile Tyr Gly Phe Phe Leu
                 85                  90                  95

Leu Phe Arg Gly Phe Phe Pro Val Val Val Gly Phe Ile Arg Arg Val
            100                 105                 110

Pro Val Leu Gly Ser Leu Leu Asn Leu Pro Gly Ile Arg Ser Phe Val
        115                 120                 125

Asp Lys Val Gly Glu Ser Asn Asn Met Val 
    130                 135



<210> 2337
<211> 157
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2337
Met Leu Thr Asp Pro Gly Ala Val Pro Lys Gly Asn Ala Thr Lys Glu
  1               5                  10                  15

Tyr Met Glu Ser Leu Gln Leu Lys Pro Gly Glu Val Ile Tyr Lys Cys
             20                  25                  30

Pro Lys Cys Cys Cys Ile Lys Pro Glu Arg Ala His His Cys Ser Ile
         35                  40                  45

Cys Lys Arg Cys Ile Arg Lys Met Asp His His Cys Pro Trp Val Asn
     50                  55                  60

Asn Cys Val Gly Glu Lys Asn Gln Arg Phe Phe Val Leu Phe Thr Met
 65                  70                  75                  80

Tyr Ile Ala Leu Ser Ser Val His Ala Leu Ile Leu Cys Gly Phe Gln
                 85                  90                  95

Phe Ile Ser Cys Val Arg Gly Gln Trp Thr Glu Cys Ser Asp Phe Ser
            100                 105                 110

Pro Pro Ile Thr Val Ile Leu Leu Ile Phe Leu Cys Leu Glu Gly Leu
        115                 120                 125

Leu Phe Phe Thr Phe Thr Xaa Ser Tyr Val Trp His Pro Asn Pro Leu
    130                 135                 140

His Met Gln Arg Arg Asp Gly Asp Arg Ala Ile Glu Lys 
145                 150                 155



<210> 2338
<211> 161
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (157)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2338
Met Gln Leu Lys Phe Leu Thr Ala Ser His Pro Lys Ser Ser Leu Pro
  1               5                  10                  15

Phe Ser Gly Val Ile Met Lys His Glu Leu Ser Ser Met Lys Ala Phe
             20                  25                  30

Val Ile Leu Ala Glu Ser Ser Ser Phe Asn Asn Ala Ala Lys Leu Leu
         35                  40                  45

Asn Ile Thr Gln Pro Ala Leu Thr Arg Arg Ile Lys Lys Met Glu Glu
     50                  55                  60

Asp Leu His Val Gln Leu Phe Glu Arg Thr Thr Arg Lys Val Thr Leu
 65                  70                  75                  80

Thr Lys Ala Gly Lys Arg Leu Leu Pro Glu Ala Arg Glu Leu Ile Lys
                 85                  90                  95

Lys Phe Asp Glu Thr Leu Phe Asn Ile Arg Asp Met Asn Ala Tyr His
            100                 105                 110

Arg Gly Met Val Thr Leu Ala Cys Ile Pro Thr Ala Val Phe Tyr Phe
        115                 120                 125

Leu Pro Leu Ala Ile Gly Lys Phe Asn Glu Leu Tyr Pro Asn Ile Lys
    130                 135                 140

Val Arg Ile Leu Glu Gln Gly Thr Asn Asn Cys Met Xaa Ile Gly Ala
145                 150                 155                 160

Val 




<210> 2339
<211> 349
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (286)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (320)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (324)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (345)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (348)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2339
Met Asn Thr Asp Thr Phe Leu Glu Glu Ile Asn Lys Val Gly Lys Glu
  1               5                  10                  15

Leu Gly Ile Ile Pro Thr Ile Ile Arg Asp Glu Glu Leu Lys Thr Arg
             20                  25                  30

Gly Phe Gly Gly Ile Tyr Gly Val Gly Lys Ala Ala Leu His Pro Pro
         35                  40                  45

Ala Leu Ala Val Leu Ser His Thr Pro Asp Gly Ala Thr Gln Thr Ile
     50                  55                  60

Ala Trp Val Gly Lys Gly Ile Val Tyr Asp Thr Gly Gly Leu Ser Ile
 65                  70                  75                  80

Lys Gly Lys Thr Thr Met Pro Gly Met Lys Arg Asp Cys Gly Gly Ala
                 85                  90                  95

Ala Ala Val Leu Gly Ala Phe Arg Ala Ala Ile Lys Gln Gly Phe Lys
            100                 105                 110

Asp Asn Leu His Ala Val Phe Cys Leu Ala Glu Asn Ser Val Gly Pro
        115                 120                 125

Asn Ala Thr Arg Pro Asp Asp Ile His Leu Leu Tyr Ser Gly Lys Thr
    130                 135                 140

Val Glu Ile Asn Asn Thr Asp Ala Glu Gly Arg Leu Val Leu Ala Asp
145                 150                 155                 160

Gly Val Ser Tyr Ala Cys Lys Asp Leu Gly Ala Asp Ile Ile Leu Asp
                165                 170                 175

Met Ala Thr Leu Thr Gly Ala Gln Gly Ile Ala Thr Gly Lys Tyr His
            180                 185                 190

Ala Ala Val Leu Thr Asn Ser Ala Glu Trp Glu Ala Ala Cys Val Lys
        195                 200                 205

Ala Gly Arg Lys Cys Gly Asp Leu Val His Pro Leu Val Tyr Cys Pro
    210                 215                 220

Glu Leu His Phe Ser Glu Phe Thr Ser Ala Val Ala Asp Met Lys Asn
225                 230                 235                 240

Ser Val Ala Asp Arg Asp Asn Ser Pro Ser Ser Cys Ala Gly Leu Phe
                245                 250                 255

Ile Ala Ser His Ile Gly Phe Asp Trp Pro Gly Val Trp Val His Leu
            260                 265                 270

Asp Ile Ala Ala Pro Val His Ala Gly Glu Arg Ala Thr Xaa Phe Gly
        275                 280                 285

Val Ala Leu Leu Leu Ala Leu Phe Gly Pro Cys Leu Leu Arg Thr Leu
    290                 295                 300

Leu Leu Glu Pro Gly Cys Pro Gln Leu Gly Cys Glu Gly Gly Cys Xaa
305                 310                 315                 320

Gly Gly Gly Xaa Gly Glu Gly Thr Ser Lys Lys Thr Gln Ser Phe Gly
                325                 330                 335

Gly Glu Ala Leu Leu Gly Leu Gly Xaa Leu Asp Xaa Asn 
            340                 345



<210> 2340
<211> 239
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2340
Met Thr Pro Val Ala Tyr His Gly His Gly Val Ser Ala Phe Arg Cys
  1               5                  10                  15

Cys Ser Pro Leu Leu Leu Gln Ala Lys Gln Glu Asp Asp Arg Asp Gly
             20                  25                  30

Leu Leu Ala Glu Arg Glu Gln Glu Glu Ala Ile Ala Gln Phe Pro Tyr
         35                  40                  45

Val Glu Phe Thr Gly Arg Asp Xaa Ile Thr Cys Leu Thr Cys Gln Gly
     50                  55                  60

Thr Gly Tyr Ile Pro Thr Glu Gln Val Asn Glu Leu Val Ala Leu Ile
 65                  70                  75                  80

Pro His Ser Asp Gln Arg Leu Arg Pro Gln Arg Thr Lys Gln Tyr Val
                 85                  90                  95

Leu Leu Ser Ile Leu Leu Cys Leu Leu Ala Ser Gly Leu Val Val Phe
            100                 105                 110

Phe Leu Phe Pro His Ser Val Leu Val Asp Asp Asp Gly Ile Lys Val
        115                 120                 125

Val Lys Val Thr Phe Asn Lys Gln Asp Ser Leu Val Ile Leu Thr Ile
    130                 135                 140

Met Ala Thr Leu Lys Ile Arg Asn Ser Asn Phe Tyr Thr Val Ala Val
145                 150                 155                 160

Thr Ser Leu Ser Ser Gln Ile Gln Tyr Met Asn Thr Val Val Asn Phe
                165                 170                 175

Thr Gly Lys Ala Glu Met Gly Gly Pro Phe Ser Tyr Val Tyr Phe Phe
            180                 185                 190

Cys Thr Val Pro Glu Ile Leu Val His Asn Ile Val Ile Phe Met Arg
        195                 200                 205

Thr Ser Val Lys Ile Ser Tyr Ile Gly Leu Met Thr Gln Ser Ser Leu
    210                 215                 220

Glu Thr His His Tyr Val Asp Cys Gly Gly Asn Ser Thr Ala Ile 
225                 230                 235



<210> 2341
<211> 275
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (268)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (274)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2341
Met Glu His Phe Asp Ala Ser Leu Ser Thr Tyr Phe Lys Ala Leu Leu
  1               5                  10                  15

Gly Pro Arg Asp Thr Arg Val Lys Gly Trp Phe Leu Leu Asp Asn Tyr
             20                  25                  30

Ile Pro Thr Phe Ile Cys Ser Val Ile Tyr Leu Leu Ile Val Trp Leu
         35                  40                  45

Gly Pro Lys Tyr Met Arg Asn Lys Gln Pro Phe Ser Cys Arg Gly Ile
     50                  55                  60

Leu Val Val Tyr Asn Leu Gly Leu Thr Leu Leu Ser Leu Tyr Met Phe
 65                  70                  75                  80

Cys Glu Leu Val Thr Gly Val Trp Glu Gly Lys Tyr Asn Phe Phe Cys
                 85                  90                  95

Gln Gly Thr Arg Thr Ala Gly Glu Ser Asp Met Lys Ile Ile Arg Val
            100                 105                 110

Leu Trp Trp Tyr Tyr Phe Ser Lys Leu Ile Glu Phe Met Asp Thr Phe
        115                 120                 125

Phe Phe Ile Leu Arg Lys Asn Asn His Gln Ile Thr Val Leu His Val
    130                 135                 140

Tyr His His Ala Ser Met Leu Asn Ile Trp Trp Phe Val Met Asn Trp
145                 150                 155                 160

Val Pro Cys Gly His Ser Tyr Phe Gly Ala Thr Leu Asn Ser Phe Ile
                165                 170                 175

His Val Leu Met Tyr Ser Tyr Tyr Gly Leu Ser Ser Val Pro Ser Met
            180                 185                 190

Arg Pro Tyr Leu Trp Trp Lys Lys Tyr Ile Thr Gln Gly Gln Leu Leu
        195                 200                 205

Gln Phe Val Leu Thr Ile Ile Gln Thr Ser Cys Gly Val Ile Trp Pro
    210                 215                 220

Cys Thr Phe Pro Leu Gly Trp Leu Tyr Phe Gln Ile Gly Tyr Met Ile
225                 230                 235                 240

Ser Leu Ile Ala Leu Phe Thr Asn Phe Tyr Ile Gln Val Asn Leu Thr
                245                 250                 255

Leu Leu Trp Asp Leu Glu Ser Gly Ala Phe Thr Xaa Lys Gly Pro His
            260                 265                 270

Leu Xaa Thr 
        275



<210> 2342
<211> 187
<212> PRT
<213> Homo sapiens

<400> 2342
Met Val Leu Leu Trp Val Val Thr Cys Pro Ala Thr Met Leu Thr Glu
  1               5                  10                  15

Pro Gln Asn Pro His Leu Ile Gly Phe Val Ala Tyr Ser Gly Pro Ser
             20                  25                  30

His Thr Thr Gln Pro His Lys Tyr Trp Leu Leu Leu Asp Gly Gln Ala
         35                  40                  45

Asp Pro Ala Ala Ala Glu Gly Pro Val Lys Arg Lys Ala Ala Ser Val
     50                  55                  60

Val Trp Trp Pro Gln Ala Leu Arg His Leu Ser Leu Leu Val His Cys
 65                  70                  75                  80

Trp Glu Glu Ser Tyr Glu Met Asn Ile Gly Cys Gln Ser Leu Trp Ala
                 85                  90                  95

Gly Gly Leu Ala Ser Ser Gly Asn Gly Trp Asp Leu Gly Val Ala Phe
            100                 105                 110

Arg Arg Asp Thr Cys Met Ser Ser Ser Ser Leu His Trp Lys Glu Phe
        115                 120                 125

Lys Tyr Ala Pro Gly Ser Leu His Tyr Phe Ala Leu Ser Phe Val Leu
    130                 135                 140

Ile Leu Thr Glu Ile Cys Leu Val Ser Ser Gly Met Gly Phe Pro Gln
145                 150                 155                 160

Glu Gly Lys His Phe Ser Val Leu Gly Ser Pro Asp Cys Ser Leu Trp
                165                 170                 175

Gly Arg Asp Glu His Val Pro Arg Glu Phe Ala 
            180                 185



<210> 2343
<211> 414
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2343
Met Ala Ala Tyr Gln Gln Glu Glu Gln Met Gln Leu Pro Arg Ala Asp
  1               5                  10                  15

Ala Ile Arg Ser Arg Leu Ile Asp Thr Phe Ser Leu Ile Glu His Leu
             20                  25                  30

Gln Gly Leu Ser Gln Ala Val Pro Arg His Thr Ile Arg Glu Leu Leu
         35                  40                  45

Asp Pro Ser Arg Gln Lys Lys Leu Val Leu Gly Asp Gln His Gln Xaa
     50                  55                  60

Val Arg Phe Ser Ile Lys Pro Gln Arg Ile Glu Gln Ile Ser His Ala
 65                  70                  75                  80

Gln Arg Leu Leu Ser Arg Leu His Val Arg Cys Ser Gln Arg Pro Pro
                 85                  90                  95

Leu Ser Leu Trp Ala Gly Trp Val Leu Glu Cys Pro Leu Phe Lys Asn
            100                 105                 110

Phe Ile Ile Phe Leu Val Phe Leu Asn Thr Ile Ile Leu Met Val Glu
        115                 120                 125

Ile Glu Leu Leu Glu Ser Thr Asn Thr Lys Leu Trp Pro Leu Lys Leu
    130                 135                 140

Thr Leu Glu Val Ala Ala Trp Phe Ile Leu Leu Ile Phe Ile Leu Glu
145                 150                 155                 160

Ile Leu Leu Lys Trp Leu Ser Asn Phe Ser Val Phe Trp Lys Ser Ala
                165                 170                 175

Trp Asn Val Phe Asp Phe Val Val Thr Met Leu Ser Leu Leu Pro Glu
            180                 185                 190

Val Val Val Leu Val Gly Val Thr Gly Gln Ser Val Trp Leu Gln Leu
        195                 200                 205

Leu Arg Ile Cys Arg Val Leu Arg Ser Leu Lys Leu Leu Ala Gln Phe
    210                 215                 220

Arg Gln Ile Gln Ile Ile Ile Leu Val Leu Val Arg Ala Leu Lys Ser
225                 230                 235                 240

Met Thr Phe Leu Leu Met Leu Leu Leu Ile Phe Phe Tyr Ile Phe Ala
                245                 250                 255

Val Thr Gly Val Tyr Val Phe Ser Glu Tyr Thr Arg Ser Pro Arg Gln
            260                 265                 270

Asp Leu Glu Tyr His Val Phe Phe Ser Asp Leu Pro Asn Ser Leu Val
        275                 280                 285

Thr Val Phe Ile Leu Phe Thr Leu Asp His Trp Tyr Ala Leu Leu Gln
    290                 295                 300

Asp Val Trp Lys Val Pro Glu Val Ser Arg Ile Phe Ser Ser Ile Tyr
305                 310                 315                 320

Phe Ile Leu Trp Leu Leu Leu Gly Ser Ile Ile Phe Arg Ser Ile Ile
                325                 330                 335

Val Ala Met Met Val Thr Asn Phe Gln Asn Ile Arg Lys Glu Leu Asn
            340                 345                 350

Glu Glu Met Ala Arg Arg Glu Val Gln Leu Lys Ala Asp Met Phe Lys
        355                 360                 365

Arg Gln Ile Ile Gln Arg Arg Lys Asn Met Ser His Glu Ala Leu Thr
    370                 375                 380

Ser Ser His Ser Lys Ile Glu Asp Arg Ser Phe Gly Leu Gly Asp Ser
385                 390                 395                 400

Cys Ala Arg Lys Ser Ala Arg Ala Asn Gly Asn Gly Ser Gly 
                405                 410



<210> 2344
<211> 207
<212> PRT
<213> Homo sapiens

<400> 2344
Met Ala Leu Gln Leu Arg Trp Phe Lys His Arg Arg Pro Phe Phe Leu
  1               5                  10                  15

Leu Leu Ile Ala Gln Leu Cys Val His Trp Pro Pro His Leu Pro Pro
             20                  25                  30

Asp Gln Arg Gly Phe Cys Leu Pro Gln His Cys Gln Pro Gly Val Phe
         35                  40                  45

Leu Asp Ser Ser Pro Gly Pro Pro Ser Ala Pro Leu Pro Pro Ser Ala
     50                  55                  60

Leu Thr Ser Arg Pro Pro Ser Leu Leu Leu Gly Asn Leu Ala Trp Val
 65                  70                  75                  80

Gly Leu Pro Ser Gln Pro Ser Arg Leu Phe Phe Leu Ser Leu Ala Ala
                 85                  90                  95

Cys Leu Ala His His Cys Gly Gln Val Ser Leu Ser Glu Asn Thr Ile
            100                 105                 110

Ser Ser His His Gly Pro Val Tyr Lys Ala Val Ser His Leu Pro Ile
        115                 120                 125

Thr Ser Asp Gln Ile Arg Thr Leu Arg Leu Trp Ile Glu Ala Asp Ala
    130                 135                 140

Thr Val Pro Gly Lys Pro His Cys Pro Pro Ile Pro Ala Leu Ala Ser
145                 150                 155                 160

Val Pro Val Arg Ser Cys Thr Met Leu Leu Ser Ala Ile Leu Pro Ser
                165                 170                 175

Pro Ala Leu Pro Ala Cys Trp Ser Cys Ile Ala Leu His Leu Thr Asp
            180                 185                 190

Ser Tyr Ser Thr Ala Leu Ala Ser Pro Lys His Thr Trp Pro Ser 
        195                 200                 205



<210> 2345
<211> 229
<212> PRT
<213> Homo sapiens

<400> 2345
Met Val Phe Gly Gly Val Val Pro Tyr Val Pro Gln Tyr Arg Asp Ile
  1               5                  10                  15

Arg Arg Thr Gln Asn Ala Asp Gly Phe Ser Thr Tyr Val Cys Leu Val
             20                  25                  30

Leu Leu Val Ala Asn Ile Leu Arg Ile Leu Phe Trp Phe Gly Arg Arg
         35                  40                  45

Phe Glu Ser Pro Leu Leu Trp Gln Ser Ala Ile Met Ile Leu Thr Met
     50                  55                  60

Leu Leu Met Leu Lys Leu Cys Thr Glu Val Arg Val Ala Asn Glu Leu
 65                  70                  75                  80

Asn Ala Arg Arg Arg Ser Phe Thr Asp Phe Asp Pro His His Phe Trp
                 85                  90                  95

Gln Trp Ser Ser Phe Ser Asp Tyr Val Gln Cys Val Leu Ala Phe Thr
            100                 105                 110

Gly Val Ala Gly Tyr Ile Thr Tyr Leu Ser Ile Asp Ser Ala Leu Phe
        115                 120                 125

Val Glu Thr Leu Gly Phe Leu Ala Val Leu Thr Glu Ala Met Leu Gly
    130                 135                 140

Val Pro Gln Leu Tyr Arg Asn His Arg His Gln Ser Thr Glu Gly Met
145                 150                 155                 160

Ser Ile Lys Met Val Leu Met Trp Thr Ser Gly Asp Ala Phe Lys Thr
                165                 170                 175

Ala Tyr Phe Leu Leu Lys Gly Ala Pro Leu Gln Phe Ser Val Cys Gly
            180                 185                 190

Leu Leu Gln Val Leu Val Asp Leu Ala Ile Leu Gly Gln Ala Tyr Ala
        195                 200                 205

Phe Ala Arg His Pro Gln Lys Pro Ala Pro His Ala Val His Pro Thr
    210                 215                 220

Gly Thr Lys Ala Leu 
225



<210> 2346
<211> 387
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (283)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2346
Met Glu Glu Glu Gly Lys Lys Gly Lys Lys Tyr Leu Gly Gln Leu Thr
  1               5                  10                  15

Ser Ile Pro Gly Tyr Leu Asn Pro Ser Ser Arg Thr Glu Ile Leu His
             20                  25                  30

Phe Ile Asp Asn Ala Lys Arg Ala His Gln Leu Pro Gly His Leu Thr
         35                  40                  45

Gln Glu His Asp Ala Val Leu Ser Leu Ser Ala Tyr Asn Val Lys Leu
     50                  55                  60

Ala Trp Arg Asp Gly Glu Asp Ile Ile Leu Arg Val Pro Ile His Asp
 65                  70                  75                  80

Ile Ala Ala Val Ser Tyr Val Arg Asp Asp Ala Ala His Leu Val Val
                 85                  90                  95

Leu Lys Thr Ala Gln Asp Pro Gly Ile Ser Pro Ser Gln Ser Leu Cys
            100                 105                 110

Ala Glu Ser Ser Arg Gly Leu Ser Ala Gly Ser Leu Ser Glu Ser Ala
        115                 120                 125

Val Gly Pro Val Glu Ala Cys Cys Leu Val Ile Leu Ala Ala Glu Ser
    130                 135                 140

Lys Val Ala Ala Glu Glu Leu Cys Cys Leu Leu Gly Gln Val Phe Gln
145                 150                 155                 160

Val Val Tyr Thr Glu Ser Thr Ile Asp Phe Leu Asp Arg Ala Ile Phe
                165                 170                 175

Asp Gly Ala Ser Thr Pro Thr His His Leu Ser Leu His Ser Asp Asp
            180                 185                 190

Ser Ser Thr Lys Val Asp Ile Lys Glu Thr Tyr Glu Val Glu Ala Ser
        195                 200                 205

Thr Phe Cys Phe Pro Glu Ser Val Asp Val Gly Gly Ala Ser Pro His
    210                 215                 220

Ser Lys Thr Ile Ser Glu Ser Glu Leu Ser Ala Xaa Ala Thr Glu Leu
225                 230                 235                 240

Leu Gln Asp Tyr Met Leu Thr Leu Arg Thr Lys Leu Ser Ser Gln Glu
                245                 250                 255

Ile Gln Gln Phe Ala Ala Leu Leu His Glu Tyr Arg Asn Gly Ala Ser
            260                 265                 270

Ile His Glu Phe Cys Ile Asn Leu Arg Gln Xaa Tyr Gly Asp Ser Arg
        275                 280                 285

Lys Phe Leu Leu Leu Gly Leu Arg Pro Phe Ile Pro Glu Lys Asp Ser
    290                 295                 300

Gln His Phe Glu Asn Phe Leu Glu Thr Ile Gly Val Lys Asp Gly Arg
305                 310                 315                 320

Gly Ile Ile Thr Asp Ser Phe Gly Arg His Arg Arg Ala Leu Ser Thr
                325                 330                 335

Thr Ser Ser Ser Thr Thr Asn Gly Asn Arg Ala Thr Gly Ser Ser Asp
            340                 345                 350

Asp Arg Ser Ala Pro Ser Glu Gly Asp Glu Trp Asp Arg Met Ile Ser
        355                 360                 365

Asp Ile Ser Ser Asp Ile Glu Ala Leu Gly Cys Ile Thr Pro Gln Gln
    370                 375                 380

Asp His Gln 
385



<210> 2347
<211> 190
<212> PRT
<213> Homo sapiens

<400> 2347
Met Lys Ala Ser Gln Cys Cys Cys Cys Leu Ser His Leu Leu Ala Ser
  1               5                  10                  15

Val Leu Leu Leu Leu Leu Leu Pro Glu Leu Ser Gly Pro Leu Ala Val
             20                  25                  30

Leu Leu Gln Ala Ala Glu Ala Ala Pro Gly Leu Gly Pro Pro Asp Pro
         35                  40                  45

Arg Pro Arg Thr Leu Pro Pro Leu Pro Pro Gly Pro Thr Pro Ala Gln
     50                  55                  60

Gln Pro Gly Arg Gly Leu Ala Glu Ala Ala Gly Pro Arg Gly Ser Glu
 65                  70                  75                  80

Gly Gly Asn Gly Ser Asn Pro Val Ala Gly Leu Glu Thr Asp Asp His
                 85                  90                  95

Gly Gly Lys Ala Gly Glu Gly Ser Val Gly Gly Gly Leu Ala Val Ser
            100                 105                 110

Pro Asn Pro Gly Asp Lys Pro Met Thr Gln Arg Ala Leu Thr Val Leu
        115                 120                 125

Met Val Val Ser Gly Ala Val Leu Val Tyr Phe Val Val Arg Thr Val
    130                 135                 140

Arg Met Arg Arg Arg Asn Arg Lys Thr Arg Arg Tyr Gly Val Leu Asp
145                 150                 155                 160

Thr Asn Ile Glu Asn Met Glu Leu Thr Pro Leu Glu Gln Asp Asp Glu
                165                 170                 175

Asp Asp Asp Asn Thr Leu Phe Asp Ala Asn His Pro Arg Arg 
            180                 185                 190



<210> 2348
<211> 140
<212> PRT
<213> Homo sapiens

<400> 2348
Met Ser Arg Phe Leu Asn Val Leu Arg Ser Trp Leu Val Met Val Ser
  1               5                  10                  15

Ile Ile Ala Met Gly Asn Thr Leu Gln Ser Phe Arg Asp His Thr Phe
             20                  25                  30

Leu Tyr Glu Lys Leu Tyr Thr Gly Lys Pro Asn Leu Val Asn Gly Leu
         35                  40                  45

Gln Ala Arg Thr Phe Gly Ile Trp Thr Leu Leu Ser Ser Val Ile Arg
     50                  55                  60

Cys Leu Cys Ala Ile Asp Ile His Asn Lys Thr Leu Tyr His Ile Thr
 65                  70                  75                  80

Leu Trp Thr Phe Leu Leu Ala Leu Gly His Phe Leu Ser Glu Leu Phe
                 85                  90                  95

Val Tyr Gly Thr Ala Ala Pro Thr Ile Gly Val Leu Ala Pro Leu Met
            100                 105                 110

Val Ala Ser Phe Ser Ile Leu Gly Met Leu Val Gly Leu Arg Tyr Leu
        115                 120                 125

Glu Val Glu Pro Val Ser Arg Gln Lys Lys Arg Asn 
    130                 135                 140



<210> 2349
<211> 155
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2349
Met Gln His Gln Leu His Leu Leu Ile Cys Trp Gly Lys Gly Ser Lys
  1               5                  10                  15

Ser Asn Thr Ser Cys Leu Gly Pro Val Leu Ser Cys Ser Asn Met Trp
             20                  25                  30

Ser Leu Ala Leu Leu Val Val Ala Gly Ser Met Gly Val Ala Tyr Ser
         35                  40                  45

Ser Val Val Met Tyr Val Leu Leu Trp Val Pro Leu Pro Xaa Pro Ser
     50                  55                  60

His Phe Leu Pro Ser Gly Ala Pro Glu Ala Gln Pro Thr Thr Trp Ala
 65                  70                  75                  80

Gln Ser Pro His Ser Val Cys Lys Cys Gly Thr Xaa Leu Gly Pro Ala
                 85                  90                  95

Lys Pro Gln Gly Pro Ser Leu Pro Xaa Pro Pro Cys Leu Ile Met Leu
            100                 105                 110

Leu Ser Cys Arg Arg Gln Leu Gly Leu Ala Pro Ser Xaa Trp Leu Pro
        115                 120                 125

Gly Xaa Gly Ser His Gly Gly Glu Leu Arg Gly Cys Ser Gln Gly Trp
    130                 135                 140

Ala Pro Gly Ile Ala His Leu Asn Ile Cys Thr 
145                 150                 155



<210> 2350
<211> 137
<212> PRT
<213> Homo sapiens

<400> 2350
Met Met Phe Ala Gly Ser Cys Gly Phe Pro Ala Gln Pro Ala Thr Thr
  1               5                  10                  15

Gly Pro Cys Gly Tyr Val Val Gln Pro Asn Thr Thr Gly Pro Phe Leu
             20                  25                  30

Tyr Val Arg Gln Phe Tyr Pro Ala Arg His Leu Trp Thr Pro Ser Pro
         35                  40                  45

Val Cys Lys Pro Ser Ile Lys Pro His Val Ser Phe Ala Gly Ser Gly
     50                  55                  60

Ser Leu Trp Arg Leu Glu Pro Tyr Ala Phe Pro Ile Glu Val Asn Arg
 65                  70                  75                  80

Gly Ser Ala Gln His Trp Val Pro Gly Met Gln Pro Cys Leu Phe Met
                 85                  90                  95

Phe Val Leu Met Gly Ile Met Trp Ala Thr Gly Ile Leu Pro Lys Ile
            100                 105                 110

Met Pro Ser Arg Lys Arg Cys Leu Ser Ile Asp Ile Pro Ala Ala Pro
        115                 120                 125

Gln Ala Gly Met Cys Leu Leu Ile Leu 
    130                 135



<210> 2351
<211> 272
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (55)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2351
Met Asn Trp Thr Tyr Val Phe Tyr Phe Phe Gly Thr Ile Gly Ile Phe
  1               5                  10                  15

Trp Phe Leu Leu Trp Ile Trp Leu Val Ser Asp Thr Pro Gln Lys His
             20                  25                  30

Lys Arg Ile Ser His Tyr Glu Lys Glu Tyr Ile Leu Ser Ser Leu Arg
         35                  40                  45

Asn Gln Leu Ser Ser Gln Xaa Ser Val Pro Trp Val Pro Ile Leu Lys
     50                  55                  60

Ser Leu Pro Leu Trp Ala Ile Val Val Ala His Phe Ser Tyr Asn Trp
 65                  70                  75                  80

Thr Phe Tyr Thr Leu Leu Thr Leu Leu Pro Thr Tyr Met Lys Glu Ile
                 85                  90                  95

Leu Arg Phe Asn Val Gln Glu Asn Gly Phe Leu Ser Ser Leu Pro Tyr
            100                 105                 110

Leu Gly Ser Trp Leu Cys Met Ile Leu Ser Gly Gln Ala Ala Asp Asn
        115                 120                 125

Leu Arg Ala Lys Trp Asn Phe Ser Thr Leu Cys Val Arg Arg Ile Phe
    130                 135                 140

Ser Leu Ile Gly Met Ile Gly Pro Ala Val Phe Leu Val Ala Ala Gly
145                 150                 155                 160

Phe Ile Gly Cys Asp Tyr Ser Leu Ala Val Ala Phe Leu Thr Ile Ser
                165                 170                 175

Thr Thr Leu Gly Gly Phe Cys Ser Ser Gly Phe Ser Ile Asn His Leu
            180                 185                 190

Asp Ile Ala Pro Ser Tyr Ala Gly Ile Leu Leu Gly Ile Thr Asn Thr
        195                 200                 205

Phe Ala Thr Ile Pro Gly Met Val Gly Pro Val Ile Ala Lys Ser Leu
    210                 215                 220

Thr Pro Asp Asn Thr Val Gly Glu Trp Gln Thr Val Phe Tyr Ile Ala
225                 230                 235                 240

Ala Ala Ile Asn Val Phe Gly Ala Ile Phe Phe Thr Leu Phe Ala Lys
                245                 250                 255

Gly Glu Val Gln Asn Trp Ala Leu Asn Asp His His Gly His Arg His
            260                 265                 270






<210> 2352
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (86)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2352
Met Leu Phe Ser Tyr Phe Ser Val Pro Ala Ala Leu Gln Arg Arg Val
  1               5                  10                  15

Leu Val Tyr Gly Val Leu Gly Ala Ile Val Leu Arg Thr Ile Met Ile
             20                  25                  30

Phe Thr Gly Ser Trp Leu Ile Ser Gln Phe Asp Trp Ile Leu Tyr Ile
         35                  40                  45

Phe Gly Ala Phe Leu Leu Phe Thr Gly Val Lys Met Ala Leu Ala His
     50                  55                  60

Glu Asp Glu Ser Gly Ile Gly Asp Lys Pro Leu Val Arg Trp Leu Xaa
 65                  70                  75                  80

Gly His Leu Arg Xaa Xaa Asp Thr Ile Asp Asn Glu His Phe Phe Val
                 85                  90                  95

Arg Lys Asn Gly Leu Leu Tyr Ala Thr Pro Leu Met Leu Val Leu Ile
            100                 105                 110

Leu Val Glu Leu Ser Asp Val Ile Phe Ala Val Asp Ser Ile Pro Ala
        115                 120                 125

Ile Phe Ala Val Thr Thr Gly Pro Val His Cys Ala Asp Leu Lys Pro
    130                 135                 140

Val Cys Asp Pro Arg Pro Ala Cys Asp Val Phe Pro Ala Gly Gly Arg
145                 150                 155                 160

Lys Glu Arg Phe Ser Met Leu Lys 
                165



<210> 2353
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2353
Met Val Lys Ile Xaa Phe Gln Pro Ala Val Ala Gly Ile Lys Gly Asp
  1               5                  10                  15

Lys Ala Asp Lys Ala Ser Ala Ser Ala Pro Ala Pro Ala Ser Ala Thr
             20                  25                  30

Glu Ile Leu Leu Thr Pro Ala Arg Glu Glu Gln Pro Pro Gln His Arg
         35                  40                  45

Ser Lys Arg Gly Ser Ser Val Gly Gly Val Cys Tyr Leu Ser Met Gly
     50                  55                  60

Met Val Val Leu Leu Met Gly Leu Val Phe Ala Ser Val Tyr Ile Cys
 65                  70                  75                  80

Thr Ile Arg Lys Val Leu Arg Ser Phe Phe Xaa Glu Gly Tyr Thr Phe
                 85                  90                  95

Leu Thr Val Xaa Ile Pro Arg Pro Gly Ala 
            100                 105



<210> 2354
<211> 235
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (192)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2354
Met Ser Ala Ser Ala Val Tyr Val Leu Asp Leu Lys Gly Lys Val Leu
  1               5                  10                  15

Ile Cys Arg Asn Tyr Arg Gly Asp Val Asp Met Ser Glu Val Glu His
             20                  25                  30

Phe Met Pro Ile Leu Met Glu Lys Glu Glu Glu Gly Met Leu Ser Pro
         35                  40                  45

Ile Leu Ala His Gly Gly Val Arg Phe Met Trp Ile Lys His Asn Asn
     50                  55                  60

Leu Tyr Leu Val Ala Thr Ser Lys Lys Asn Ala Cys Val Ser Leu Val
 65                  70                  75                  80

Phe Ser Phe Leu Tyr Lys Val Val Gln Val Phe Ser Glu Tyr Phe Lys
                 85                  90                  95

Glu Leu Glu Glu Glu Ser Ile Arg Asp Asn Phe Val Ile Ile Tyr Glu
            100                 105                 110

Leu Leu Asp Glu Leu Met Asp Phe Gly Tyr Pro Gln Thr Thr Asp Ser
        115                 120                 125

Lys Ile Leu Gln Glu Tyr Ile Thr Gln Glu Gly His Lys Leu Glu Thr
    130                 135                 140

Gly Ala Pro Arg Pro Pro Ala Thr Val Thr Asn Ala Val Ser Trp Arg
145                 150                 155                 160

Ser Glu Gly Ile Lys Tyr Arg Lys Asn Glu Val Phe Leu Asp Val Ile
                165                 170                 175

Glu Ser Val Asn Leu Leu Val Ser Ala Asn Gly Asn Val Leu Arg Xaa
            180                 185                 190

Arg Ser Trp Ala Pro Ser Arg Cys Glu Ser Ser Ser Arg Ala Cys Pro
        195                 200                 205

Ser Cys Ala Trp Ala Ser Thr Thr Arg Ser Ser Leu Thr Thr Arg Ala
    210                 215                 220

Ala Ala Lys Ala Asn Pro Trp Ser Trp Arg Met 
225                 230                 235



<210> 2355
<211> 452
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (278)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2355
Met Asp Arg Pro Ile Ala Gly Tyr Ala Asn Leu Cys Pro Asn Met Ile
  1               5                  10                  15

Ser Thr Gln Pro Gln Glu Phe Val Gly Met Leu Ser Thr Val Lys His
             20                  25                  30

Glu Val Ile His Ala Leu Gly Phe Ser Ala Gly Leu Phe Ala Phe Tyr
         35                  40                  45

His Asp Lys Asp Gly Asn Pro Leu Thr Ser Arg Phe Ala Asp Gly Leu
     50                  55                  60

Pro Pro Phe Asn Tyr Ser Leu Gly Leu Tyr Gln Trp Ser Asp Lys Val
 65                  70                  75                  80

Val Arg Lys Val Xaa Arg Leu Trp Asp Val Arg Asp Asn Lys Ile Val
                 85                  90                  95

Arg His Thr Val Tyr Leu Leu Val Thr Pro Arg Val Val Glu Glu Ala
            100                 105                 110

Arg Lys His Phe Asp Cys Pro Val Leu Glu Gly Met Glu Leu Glu Asn
        115                 120                 125

Gln Gly Gly Val Gly Thr Glu Leu Asn His Trp Glu Lys Arg Leu Leu
    130                 135                 140

Glu Asn Glu Ala Met Thr Gly Ser His Thr Gln Asn Arg Val Leu Ser
145                 150                 155                 160

Arg Ile Thr Leu Ala Leu Met Glu Asp Thr Gly Trp Tyr Lys Ala Asn
                165                 170                 175

Tyr Ser Met Ala Glu Lys Leu Asp Trp Gly Arg Gly Met Gly Cys Asp
            180                 185                 190

Phe Val Arg Lys Ser Cys Lys Phe Trp Ile Asp Gln Gln Arg Gln Lys
        195                 200                 205

Arg Gln Met Leu Ser Pro Tyr Cys Asp Thr Leu Arg Ser Asn Pro Leu
    210                 215                 220

Gln Leu Thr Cys Arg Gln Asp Gln Arg Ala Val Ala Val Cys Asn Leu
225                 230                 235                 240

Gln Lys Phe Pro Lys Pro Leu Pro Gln Glu Tyr Gln Tyr Phe Asp Glu
                245                 250                 255

Leu Ser Gly Ile Pro Ala Glu Asp Leu Pro Tyr Tyr Gly Gly Ser Val
            260                 265                 270

Glu Ile Ala Asp Tyr Xaa Pro Phe Ser Gln Glu Phe Ser Trp His Leu
        275                 280                 285

Ser Gly Glu Tyr Gln Arg Ser Ser Asp Cys Arg Ile Leu Glu Asn Gln
    290                 295                 300

Pro Glu Ile Phe Lys Asn Tyr Gly Ala Glu Lys Tyr Gly Pro His Ser
305                 310                 315                 320

Val Cys Leu Ile Gln Lys Ser Ala Phe Val Met Glu Lys Cys Glu Arg
                325                 330                 335

Lys Leu Ser Tyr Pro Asp Trp Gly Ser Gly Cys Tyr Gln Val Ser Cys
            340                 345                 350

Ser Pro Gln Gly Leu Lys Val Trp Val Gln Asp Thr Ser Tyr Leu Cys
        355                 360                 365

Ser Arg Ala Gly Gln Val Leu Pro Val Ser Ile Gln Met Asn Gly Trp
    370                 375                 380

Ile His Asp Gly Asn Leu Leu Cys Pro Ser Cys Trp Asp Phe Cys Glu
385                 390                 395                 400

Leu Cys Pro Pro Glu Thr Asp Pro Pro Ala Thr Asn Leu Thr Arg Ala
                405                 410                 415

Leu Pro Leu Asp Leu Cys Ser Cys Ser Ser Ser Leu Val Val Thr Leu
            420                 425                 430

Trp Leu Leu Leu Gly Asn Leu Phe Pro Leu Leu Ala Gly Phe Leu Leu
        435                 440                 445

Cys Ile Trp His 
    450



<210> 2356
<211> 487
<212> PRT
<213> Homo sapiens

<400> 2356
Met Phe Ala Asp Ser Asn Glu Asn Glu Thr Val Phe Ala Pro Val Ile
  1               5                  10                  15

Gln Ala Gly Met Glu Ala Leu Lys Ala Ala Asp Cys Pro Gly Lys Leu
             20                  25                  30

Phe Ile Phe His Ser Ser Leu Pro Thr Ala Glu Ala Pro Gly Lys Leu
         35                  40                  45

Lys Asn Arg Asp Asp Lys Lys Leu Val Asn Thr Asp Lys Glu Lys Ile
     50                  55                  60

Leu Phe Gln Pro Gln Thr Asn Val Tyr Asp Ser Leu Ala Lys Asp Cys
 65                  70                  75                  80

Val Ala His Gly Cys Ser Val Thr Leu Phe Leu Phe Pro Ser Gln Tyr
                 85                  90                  95

Val Asp Val Ala Ser Leu Gly Leu Val Pro Gln Leu Thr Gly Gly Thr
            100                 105                 110

Leu Tyr Lys Tyr Asn Asn Phe Gln Met His Leu Asp Arg Gln Gln Phe
        115                 120                 125

Leu Asn Asp Leu Arg Asn Asp Ile Glu Lys Lys Ile Gly Phe Asp Ala
    130                 135                 140

Ile Met Arg Val Arg Thr Ser Thr Gly Phe Arg Ala Thr Asp Phe Phe
145                 150                 155                 160

Gly Gly Ile Leu Met Asn Asn Thr Thr Asp Val Glu Met Ala Ala Ile
                165                 170                 175

Asp Cys Asp Lys Ala Val Thr Val Glu Phe Lys His Asp Asp Lys Leu
            180                 185                 190

Ser Glu Asp Ser Gly Ala Leu Ile Gln Cys Ala Val Leu Tyr Thr Thr
        195                 200                 205

Ile Ser Gly Gln Arg Arg Leu Arg Ile His Asn Leu Gly Leu Asn Cys
    210                 215                 220

Ser Ser Gln Leu Ala Asp Leu Tyr Lys Ser Cys Glu Thr Asp Ala Leu
225                 230                 235                 240

Ile Asn Phe Phe Ala Lys Ser Ala Phe Lys Ala Val Leu His Gln Pro
                245                 250                 255

Leu Lys Val Ile Arg Glu Ile Leu Val Asn Gln Thr Ala His Met Leu
            260                 265                 270

Ala Cys Tyr Arg Lys Asn Cys Ala Ser Pro Ser Ala Ala Ser Gln Leu
        275                 280                 285

Ile Leu Pro Asp Ser Met Lys Val Leu Pro Val Tyr Met Asn Cys Leu
    290                 295                 300

Leu Lys Asn Cys Val Leu Leu Ser Arg Pro Glu Ile Ser Thr Asp Glu
305                 310                 315                 320

Arg Ala Tyr Gln Arg Gln Leu Val Met Thr Met Gly Val Ala Asp Ser
                325                 330                 335

Gln Leu Phe Phe Tyr Pro Gln Leu Leu Pro Ile His Thr Leu Asp Val
            340                 345                 350

Lys Ser Thr Met Leu Pro Ala Ala Val Arg Cys Ser Glu Ser Arg Leu
        355                 360                 365

Ser Glu Glu Gly Ile Phe Leu Leu Ala Asn Gly Leu His Met Phe Leu
    370                 375                 380

Trp Leu Gly Val Ser Ser Pro Pro Glu Leu Ile Gln Gly Ile Phe Asn
385                 390                 395                 400

Val Pro Ser Phe Ala His Ile Asn Thr Asp Met Thr Leu Leu Pro Glu
                405                 410                 415

Val Gly Asn Pro Tyr Ser Gln Gln Leu Arg Met Ile Met Gly Ile Ile
            420                 425                 430

Gln Gln Lys Arg Pro Tyr Ser Met Lys Leu Thr Ile Val Lys Gln Arg
        435                 440                 445

Glu Gln Pro Glu Met Val Phe Arg Gln Phe Leu Val Glu Asp Lys Gly
    450                 455                 460

Leu Tyr Gly Gly Ser Ser Tyr Val Asp Phe Leu Cys Cys Val His Lys
465                 470                 475                 480

Glu Ile Cys Gln Leu Leu Asn 
                485



<210> 2357
<211> 310
<212> PRT
<213> Homo sapiens

<400> 2357
Met Lys Pro Leu Arg Met Ala Arg Pro Gly Gly Pro Glu His Asn Glu
  1               5                  10                  15

Tyr Ala Leu Val Ser Ala Trp His Ser Ser Gly Ser Tyr Leu Asp Ser
             20                  25                  30

Glu Gly Leu Arg His Gln Asp Asp Phe Asp Val Ser Leu Leu Val Cys
         35                  40                  45

His Cys Ala Ala Pro Phe Glu Glu Gln Gly Glu Ala Glu Arg His Val
     50                  55                  60

Leu Arg Leu Gln Phe Phe Val Val Leu Thr Ser Gln Arg Glu Leu Phe
 65                  70                  75                  80

Pro Arg Leu Thr Ala Asp Met Arg Arg Phe Arg Lys Pro Pro Arg Leu
                 85                  90                  95

Pro Pro Glu Pro Glu Ala Pro Gly Ser Ser Ala Gly Ser Pro Gly Glu
            100                 105                 110

Ala Ser Gly Leu Ile Leu Ala Pro Gly Pro Ala Pro Leu Phe Pro Pro
        115                 120                 125

Leu Ala Ala Glu Val Gly Met Ala Arg Ala Arg Leu Ala Gln Leu Val
    130                 135                 140

Arg Leu Ala Gly Gly His Cys Arg Arg Asp Thr Leu Trp Lys Arg Leu
145                 150                 155                 160

Phe Leu Leu Glu Pro Pro Gly Pro Asp Arg Leu Arg Leu Gly Gly Arg
                165                 170                 175

Leu Ala Leu Ala Glu Leu Glu Glu Leu Leu Glu Ala Val His Ala Lys
            180                 185                 190

Ser Ile Gly Asp Ile Asp Pro Gln Leu Asp Cys Phe Leu Ser Met Thr
        195                 200                 205

Val Ser Trp Tyr Gln Ser Leu Ile Lys Val Leu Leu Ser Arg Phe Pro
    210                 215                 220

Gln Ser Cys Arg His Phe Gln Ser Pro Asp Leu Gly Thr Gln Tyr Leu
225                 230                 235                 240

Val Val Leu Asn Gln Lys Phe Thr Asp Cys Phe Val Leu Val Phe Leu
                245                 250                 255

Asp Ser His Leu Gly Lys Thr Ser Leu Thr Val Val Phe Arg Glu Pro
            260                 265                 270

Phe Pro Val Gln Pro Gln Asp Ser Glu Ser Pro Pro Ala Gln Leu Val
        275                 280                 285

Ser Thr Tyr His His Leu Glu Ser Val Ile Asn Thr Ala Cys Phe Thr
    290                 295                 300

Leu Trp Thr Arg Leu Leu 
305                 310



<210> 2358
<211> 474
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2358
Met Trp Val Glu Pro Glu Ala Ala Ala Tyr Ala Pro Pro Pro Pro Ala
  1               5                  10                  15

Lys Lys Pro Arg Lys Ser Thr Ala Glu Lys Pro Lys Val Lys Glu Ile
             20                  25                  30

Ile Asp Glu Arg Thr Arg Glu Arg Leu Val Tyr Glu Val Arg Gln Lys
         35                  40                  45

Cys Arg Asn Ile Glu Asp Ile Cys Ile Ser Cys Gly Ser Leu Asn Val
     50                  55                  60

Thr Leu Glu His Pro Leu Phe Val Gly Gly Met Cys Gln Asn Cys Lys
 65                  70                  75                  80

Asn Cys Phe Leu Glu Cys Ala Tyr Gln Tyr Asp Asp Asp Gly Tyr Gln
                 85                  90                  95

Ser Tyr Cys Thr Ile Cys Cys Gly Gly Arg Glu Val Leu Met Cys Gly
            100                 105                 110

Asn Asn Asn Cys Cys Arg Cys Phe Cys Val Glu Cys Val Asp Leu Leu
        115                 120                 125

Val Gly Pro Gly Ala Xaa Gln Ala Xaa Ile Lys Glu Asp Pro Trp Asn
    130                 135                 140

Cys Tyr Met Cys Gly His Lys Gly Thr Tyr Gly Leu Leu Arg Arg Arg
145                 150                 155                 160

Glu Asp Trp Pro Ser Arg Xaa Gln Met Phe Phe Ala Asn Asn His Asp
                165                 170                 175

Gln Glu Phe Asp Pro Pro Lys Val Tyr Pro Pro Val Pro Ala Glu Lys
            180                 185                 190

Arg Lys Pro Ile Arg Val Leu Ser Leu Phe Asp Gly Ile Ala Thr Gly
        195                 200                 205

Leu Leu Val Leu Lys Asp Leu Gly Ile Gln Val Asp Arg Tyr Ile Ala
    210                 215                 220

Ser Glu Val Cys Glu Asp Ser Ile Thr Val Gly Met Val Arg His Gln
225                 230                 235                 240

Gly Lys Ile Met Tyr Val Gly Asp Val Arg Ser Val Thr Gln Lys His
                245                 250                 255

Ile Gln Glu Trp Gly Pro Phe Asp Leu Val Ile Gly Gly Ser Pro Cys
            260                 265                 270

Asn Asp Leu Ser Ile Val Asn Pro Ala Arg Lys Gly Leu Tyr Glu Gly
        275                 280                 285

Thr Gly Arg Leu Phe Phe Glu Phe Tyr Arg Leu Leu His Asp Ala Arg
    290                 295                 300

Pro Lys Glu Gly Asp Asp Arg Pro Phe Phe Trp Leu Phe Glu Asn Val
305                 310                 315                 320

Val Ala Met Gly Val Ser Asp Lys Arg Asp Ile Ser Arg Phe Leu Glu
                325                 330                 335

Ser Asn Pro Val Met Ile Asp Ala Lys Glu Val Ser Ala Ala His Arg
            340                 345                 350

Ala Arg Tyr Phe Trp Gly Asn Leu Pro Gly Met Asn Arg Pro Leu Ala
        355                 360                 365

Ser Thr Val Asn Asp Lys Leu Glu Leu Gln Glu Cys Leu Glu His Gly
    370                 375                 380

Arg Ile Ala Lys Phe Ser Lys Val Arg Thr Ile Thr Thr Arg Ser Asn
385                 390                 395                 400

Ser Ile Lys Gln Gly Lys Asp Gln His Phe Pro Val Phe Met Asn Glu
                405                 410                 415

Lys Glu Asp Ile Leu Trp Cys Thr Glu Met Glu Arg Val Phe Gly Phe
            420                 425                 430

Pro Val His Tyr Thr Asp Val Ser Asn Met Ser Arg Leu Ala Arg Gln
        435                 440                 445

Arg Leu Leu Gly Arg Ser Trp Ser Val Pro Val Ile Arg His Leu Phe
    450                 455                 460

Ala Pro Leu Lys Glu Tyr Phe Ala Cys Val 
465                 470



<210> 2359
<211> 545
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (534)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (536)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2359
Met Ala Thr Ser Gly Ala Ala Ser Ala Glu Leu Val Ile Gly Trp Cys
  1               5                  10                  15

Ile Phe Gly Leu Leu Leu Leu Ala Ile Leu Ala Phe Cys Trp Ile Tyr
             20                  25                  30

Val Arg Lys Tyr Gln Ser Arg Arg Glu Ser Glu Val Val Ser Thr Ile
         35                  40                  45

Thr Ala Ile Phe Ser Leu Ala Ile Ala Leu Ile Thr Ser Ala Leu Leu
     50                  55                  60

Pro Val Asp Ile Phe Leu Val Ser Tyr Met Lys Asn Gln Asn Gly Thr
 65                  70                  75                  80

Phe Lys Asp Trp Ala Asn Ala Asn Val Ser Arg Gln Ile Glu Asp Thr
                 85                  90                  95

Val Leu Tyr Gly Tyr Tyr Thr Leu Tyr Ser Val Ile Leu Phe Cys Val
            100                 105                 110

Phe Phe Trp Ile Pro Phe Val Tyr Phe Tyr Tyr Glu Glu Lys Asp Asp
        115                 120                 125

Asp Asp Thr Ser Lys Cys Thr Gln Ile Lys Thr Ala Leu Lys Tyr Thr
    130                 135                 140

Leu Gly Phe Val Val Ile Cys Ala Leu Leu Leu Leu Val Gly Ala Phe
145                 150                 155                 160

Val Pro Leu Asn Val Pro Asn Asn Lys Asn Ser Thr Glu Trp Glu Lys
                165                 170                 175

Val Lys Ser Leu Phe Glu Glu Leu Gly Ser Ser His Gly Leu Ala Ala
            180                 185                 190

Leu Ser Phe Ser Ile Ser Ser Leu Thr Leu Ile Gly Met Leu Ala Ala
        195                 200                 205

Ile Thr Tyr Thr Ala Tyr Gly Met Ser Ala Leu Pro Leu Asn Leu Ile
    210                 215                 220

Lys Gly Thr Arg Ser Ala Ala Tyr Glu Arg Leu Glu Asn Thr Glu Asp
225                 230                 235                 240

Ile Glu Glu Val Glu Gln His Ile Gln Thr Ile Lys Ser Lys Ser Lys
                245                 250                 255

Asp Gly Arg Pro Leu Pro Ala Arg Asp Lys Arg Ala Leu Lys Gln Phe
            260                 265                 270

Glu Glu Arg Leu Arg Thr Leu Lys Lys Arg Glu Arg His Leu Glu Phe
        275                 280                 285

Ile Glu Asn Ser Trp Trp Thr Lys Phe Cys Gly Ala Leu Arg Pro Leu
    290                 295                 300

Lys Ile Val Trp Gly Ile Phe Phe Ile Leu Val Ala Leu Leu Phe Val
305                 310                 315                 320

Ile Ser Leu Phe Leu Ser Asn Leu Asp Lys Ala Leu His Ser Ala Gly
                325                 330                 335

Ile Asp Ser Gly Phe Ile Ile Phe Gly Ala Asn Leu Ser Asn Pro Leu
            340                 345                 350

Asn Met Leu Leu Pro Leu Leu Gln Thr Val Phe Pro Leu Asp Tyr Ile
        355                 360                 365

Leu Ile Thr Ile Ile Ile Met Tyr Phe Ile Phe Thr Ser Met Ala Gly
    370                 375                 380

Ile Arg Asn Ile Gly Ile Trp Phe Phe Trp Ile Arg Leu Tyr Lys Ile
385                 390                 395                 400

Arg Arg Gly Arg Thr Arg Pro Gln Ala Leu Leu Phe Leu Cys Met Ile
                405                 410                 415

Leu Leu Leu Ile Val Leu His Thr Ser Tyr Met Ile Tyr Ser Leu Ala
            420                 425                 430

Pro Gln Tyr Val Met Tyr Gly Ser Gln Asn Tyr Leu Ile Glu Thr Asn
        435                 440                 445

Ile Thr Ser Asp Asn His Lys Gly Asn Ser Thr Leu Ser Val Pro Lys
    450                 455                 460

Arg Cys Asp Ala Asp Ala Pro Glu Asp Gln Cys Thr Val Thr Arg Thr
465                 470                 475                 480

Tyr Leu Phe Leu His Lys Phe Trp Phe Phe Ser Ala Ala Tyr Tyr Phe
                485                 490                 495

Gly Asn Trp Ala Phe Leu Gly Val Phe Leu Ile Gly Leu Ile Val Ser
            500                 505                 510

Cys Cys Lys Gly Lys Lys Ser Val Ile Glu Gly Val Asp Glu Asp Ser
        515                 520                 525

Asp Ile Arg Val Val Xaa Glu Xaa Leu Gly Val Leu Glu Gln Thr Gly
    530                 535                 540

Pro 
545



<210> 2360
<211> 148
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2360
Met Lys Arg Phe Leu Gly Pro Cys Gly Trp Lys Tyr Glu Asn Ile Tyr
  1               5                  10                  15

Ile Thr Arg Gln Phe Val Gln Phe Asp Glu Arg Glu Arg His Gln Gln
             20                  25                  30

Arg Pro Cys Val Leu Pro Leu Asn Lys Glu Glu Arg Arg Lys Tyr Val
         35                  40                  45

Ile Ile Pro Thr Phe Trp Pro Thr Pro Lys Glu Arg Lys Asn Leu Gly
     50                  55                  60

Leu Phe Phe Leu Pro Ile Leu Ile His Leu Cys Ile Trp Val Leu Xaa
 65                  70                  75                  80

Ala Ala Val Asp Tyr Leu Leu Tyr Arg Leu Ile Phe Ser Val Ser Lys
                 85                  90                  95

Gln Phe Gln Ser Leu Pro Gly Phe Glu Val His Leu Lys Leu His Gly
            100                 105                 110

Glu Lys Gln Gly Thr Gln Asp Ile Ile His Asp Ser Ser Phe Asn Ile
        115                 120                 125

Ser Val Phe Glu Pro Asn Cys Ile Pro Lys Pro Trp Gln Ala Leu Lys
    130                 135                 140

Leu Leu Ala His 
145



<210> 2361
<211> 264
<212> PRT
<213> Homo sapiens

<400> 2361
Met Arg Pro Leu Leu Gly Leu Leu Leu Val Phe Ala Gly Cys Thr Phe
  1               5                  10                  15

Ala Leu Tyr Leu Leu Ser Thr Arg Leu Pro Arg Gly Arg Arg Leu Gly
             20                  25                  30

Ser Thr Glu Glu Ala Gly Gly Arg Ser Leu Trp Phe Pro Ser Asp Leu
         35                  40                  45

Ala Glu Leu Arg Glu Leu Ser Glu Val Leu Arg Glu Tyr Arg Lys Glu
     50                  55                  60

His Gln Ala Tyr Val Phe Leu Leu Phe Cys Gly Ala Tyr Leu Tyr Lys
 65                  70                  75                  80

Gln Gly Phe Ala Ile Pro Gly Ser Ser Phe Leu Asn Val Leu Ala Gly
                 85                  90                  95

Ala Leu Phe Gly Pro Trp Leu Gly Leu Leu Leu Cys Cys Val Leu Thr
            100                 105                 110

Ser Val Gly Ala Thr Cys Cys Tyr Leu Leu Ser Ser Ile Phe Gly Lys
        115                 120                 125

Gln Leu Val Val Ser Tyr Phe Pro Asp Lys Val Ala Leu Leu Gln Arg
    130                 135                 140

Lys Val Glu Glu Asn Arg Asn Ser Leu Phe Phe Phe Leu Leu Phe Leu
145                 150                 155                 160

Arg Leu Phe Pro Met Thr Pro Asn Trp Phe Leu Asn Leu Ser Ala Pro
                165                 170                 175

Ile Leu Asn Ile Pro Ile Val Gln Phe Phe Phe Ser Val Leu Ile Gly
            180                 185                 190

Leu Ile Pro Tyr Asn Phe Ile Cys Val Gln Thr Gly Ser Ile Leu Ser
        195                 200                 205

Thr Leu Thr Ser Leu Asp Ala Leu Phe Ser Trp Asp Thr Val Phe Lys
    210                 215                 220

Leu Leu Ala Ile Ala Met Val Ala Leu Ile Pro Gly Thr Leu Ile Lys
225                 230                 235                 240

Lys Phe Ser Gln Lys His Leu Gln Leu Asn Glu Thr Ser Thr Ala Asn
                245                 250                 255

His Ile His Ser Arg Lys Asp Thr 
            260



<210> 2362
<211> 300
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2362
Met Leu Met His His Gln Lys Tyr Leu Gln Arg Phe Leu Gly Gly Lys
  1               5                  10                  15

Arg Glu Lys Lys Gln Lys Glu Ala Cys Ser Ile Pro Gly Ile Gly Xaa
             20                  25                  30

Arg Met Ala Xaa Lys Ile Ile Glu Ile Leu Glu Ser Gly His Leu Arg
         35                  40                  45

Lys Leu Asp His Ile Ser Glu Ser Val Pro Val Leu Glu Leu Phe Ser
     50                  55                  60

Asn Ile Trp Gly Ala Gly Thr Lys Thr Ala Gln Met Trp Tyr Gln Gln
 65                  70                  75                  80

Gly Phe Arg Ser Leu Glu Asp Ile Arg Ser Gln Ala Ser Leu Thr Thr
                 85                  90                  95

Gln Gln Ala Ile Gly Leu Lys His Tyr Ser Asp Phe Leu Glu Arg Met
            100                 105                 110

Pro Arg Glu Glu Ala Thr Glu Ile Glu Gln Thr Val Gln Lys Ala Ala
        115                 120                 125

Gln Ala Phe Asn Ser Gly Leu Leu Cys Val Ala Cys Gly Ser Tyr Arg
    130                 135                 140

Arg Gly Lys Ala Thr Cys Gly Asp Val Asp Val Leu Ile Thr His Pro
145                 150                 155                 160

Asp Gly Xaa Ser His Arg Xaa Ile Phe Ser Arg Leu Leu Asp Ser Leu
                165                 170                 175

Arg Gln Glu Gly Phe Leu Thr Asp Asp Leu Val Ser Gln Glu Glu Asn
            180                 185                 190

Gly Gln Gln Gln Lys Tyr Leu Gly Val Cys Arg Leu Pro Gly Pro Gly
        195                 200                 205

Arg Arg His Arg Arg Leu Asp Ile Ile Val Val Pro Tyr Ser Glu Phe
    210                 215                 220

Ala Cys Ala Leu Leu Tyr Phe Thr Gly Ser Ala His Phe Asn Arg Ser
225                 230                 235                 240

Met Arg Ala Leu Ala Lys Thr Lys Gly Met Ser Leu Ser Glu His Ala
                245                 250                 255

Leu Ser Thr Ala Val Val Arg Asn Thr His Gly Cys Lys Val Gly Pro
            260                 265                 270

Gly Arg Val Leu Pro Thr Pro Thr Glu Lys Asp Val Phe Arg Leu Leu
        275                 280                 285

Gly Leu Pro Tyr Arg Glu Pro Ala Glu Arg Asp Trp 
    290                 295                 300



<210> 2363
<211> 275
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (181)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2363
Met Ile Lys Ser Ala Ala His Pro His Ser Gln Cys Ser Ser His Leu
  1               5                  10                  15

Gly Gly Glu Thr Pro Pro Gly Cys Gly Thr Arg Leu Pro Ala Leu Arg
             20                  25                  30

Gly His Glu Ser Gly Gly Asn Ala Pro Val Glu Gly Gln Gln Pro Trp
         35                  40                  45

Gly Gly Glu Gln Pro Gly Leu Trp Glu Asn His Gln Arg Xaa Ala Ser
     50                  55                  60

Leu His Leu Ala Pro Ala Glu Glu Pro His Val His Pro Ala Leu Pro
 65                  70                  75                  80

Gly Arg Gly His Arg Gly His Ser His His Arg His Val His Val Gln
                 85                  90                  95

Pro Gln Val Leu Gly Val Pro Val Gln Pro Glu Cys Leu Arg Ser Cys
            100                 105                 110

His Leu Val Trp Val Pro Gly Gly Ala Ser Gly Trp Trp Arg His Leu
        115                 120                 125

Pro Gly Arg Leu Leu Cys Glu Gln Ala Gln Ala Pro Gly Leu Arg Gly
    130                 135                 140

His Gln Val Leu Pro Val Leu His Arg Cys Gln Xaa Ala Gly His Pro
145                 150                 155                 160

Arg Leu Leu Thr Ala Leu Pro Gln Cys Ala His Ala Gly Xaa Thr Ala
                165                 170                 175

Ser Tyr Gly Gly Xaa Ser Cys Pro Lys Pro Pro Glu Pro Asn Gly Ser
            180                 185                 190

Leu Gln Arg Cys Leu His Cys Gln Pro Glu His Tyr Ser Pro Val Cys
        195                 200                 205

Gly Ser Asp Gly Leu Met Tyr Phe Ser Leu Cys His Ala Gly Ala Leu
    210                 215                 220

Gln Pro Arg Arg Arg Met Trp Thr Ala Arg Arg Cys Thr Glu Thr Val
225                 230                 235                 240

Ala Val Ser Leu Arg Ile Phe Pro Leu Val Leu Ala Met Pro Leu Gln
                245                 250                 255

Gly Asn Ala Leu Gln Leu Val Arg Glu Ser Pro Ser Phe Trp Phe Ser
            260                 265                 270

Tyr Ser Leu 
        275



<210> 2364
<211> 642
<212> PRT
<213> Homo sapiens

<400> 2364
Met Pro Cys Gly Glu Asp Trp Leu Ser His Pro Leu Gly Ile Val Gln
  1               5                  10                  15

Gly Phe Phe Ala Gln Asn Gly Val Asn Pro Asp Trp Glu Lys Lys Val
             20                  25                  30

Ile Glu Tyr Phe Lys Glu Lys Leu Lys Glu Asn Asn Ala Pro Lys Trp
         35                  40                  45

Val Pro Ser Leu Asn Glu Val Pro Leu His Tyr Leu Lys Pro Asn Ser
     50                  55                  60

Phe Val Lys Phe Arg Cys Met Ile Gln Asp Met Phe Asp Pro Glu Phe
 65                  70                  75                  80

Tyr Met Gly Val Tyr Glu Thr Val Asn Gln Asn Thr Lys Ala His Val
                 85                  90                  95

Leu His Phe Gly Lys Tyr Arg Asp Val Ala Glu Cys Gly Pro Gln Gln
            100                 105                 110

Glu Leu Asp Leu Asn Ser Pro Arg Asn Thr Thr Leu Glu Arg Gln Thr
        115                 120                 125

Phe Tyr Cys Val Pro Val Pro Gly Glu Ser Thr Trp Val Lys Glu Ala
    130                 135                 140

Tyr Val Asn Ala Asn Gln Ala Arg Val Ser Pro Ser Thr Ser Tyr Thr
145                 150                 155                 160

Pro Ser Arg His Lys Arg Ser Tyr Glu Asp Asp Asp Asp Met Asp Leu
                165                 170                 175

Gln Pro Asn Lys Gln Lys Asp Gln His Ala Gly Ala Arg Gln Ala Gly
            180                 185                 190

Ser Val Gly Gly Leu Gln Trp Cys Gly Glu Pro Lys Arg Leu Glu Thr
        195                 200                 205

Glu Ala Ser Thr Gly Gln Gln Leu Asn Ser Leu Asn Leu Ser Ser Pro
    210                 215                 220

Phe Asp Leu Asn Phe Pro Leu Pro Gly Glu Lys Gly Pro Ala Cys Leu
225                 230                 235                 240

Val Lys Val Tyr Glu Asp Trp Asp Cys Phe Lys Val Asn Asp Ile Leu
                245                 250                 255

Glu Leu Tyr Gly Ile Leu Ser Val Asp Pro Val Leu Ser Ile Leu Asn
            260                 265                 270

Asn Asp Glu Arg Asp Ala Ser Ala Leu Leu Asp Pro Met Glu Cys Thr
        275                 280                 285

Asp Thr Ala Glu Glu Gln Arg Val His Ser Pro Pro Ala Ser Leu Val
    290                 295                 300

Pro Arg Ile His Val Ile Leu Ala Gln Lys Leu Gln His Ile Asn Pro
305                 310                 315                 320

Leu Leu Pro Ala Cys Leu Asn Lys Glu Glu Ser Lys Thr Cys Lys Phe
                325                 330                 335

Val Ser Ser Phe Met Ser Glu Leu Ser Pro Val Arg Ala Glu Leu Leu
            340                 345                 350

Gly Phe Leu Thr His Ala Leu Leu Gly Asp Ser Leu Ala Ala Glu Tyr
        355                 360                 365

Leu Ile Leu His Leu Ile Ser Thr Val Tyr Thr Arg Arg Asp Val Leu
    370                 375                 380

Pro Leu Gly Lys Phe Thr Val Asn Leu Ser Gly Cys Pro Arg Asn Ser
385                 390                 395                 400

Thr Phe Thr Glu His Leu Tyr Arg Ile Ile Gln His Leu Val Pro Ala
                405                 410                 415

Ser Phe Arg Leu Gln Met Thr Ile Glu Asn Met Asn His Leu Lys Phe
            420                 425                 430

Ile Pro His Lys Asp Tyr Thr Ala Asn Arg Leu Val Ser Gly Leu Leu
        435                 440                 445

Gln Leu Pro Ser Asn Thr Ser Leu Val Ile Asp Glu Thr Leu Leu Glu
    450                 455                 460

Gln Gly Gln Leu Asp Thr Pro Gly Val His Asn Val Thr Ala Leu Ser
465                 470                 475                 480

Asn Leu Ile Thr Trp Gln Lys Val Asp Tyr Asp Phe Ser Tyr His Gln
                485                 490                 495

Met Glu Phe Pro Cys Asn Ile Asn Val Phe Ile Thr Ser Glu Gly Arg
            500                 505                 510

Ser Leu Leu Pro Ala Asp Cys Gln Ile His Leu Gln Pro Gln Leu Ile
        515                 520                 525

Pro Pro Asn Met Glu Glu Tyr Met Asn Ser Leu Leu Ser Ala Val Leu
    530                 535                 540

Pro Ser Val Leu Asn Lys Phe Arg Ile Tyr Leu Thr Leu Leu Arg Phe
545                 550                 555                 560

Leu Glu Tyr Ser Ile Ser Asp Glu Ile Thr Lys Ala Val Glu Asp Asp
                565                 570                 575

Phe Val Glu Met Arg Lys Asn Asp Pro Gln Ser Ile Thr Ala Asp Asp
            580                 585                 590

Leu His Gln Leu Leu Val Val Ala Arg Cys Leu Ser Leu Ser Ala Gly
        595                 600                 605

Gln Thr Thr Leu Ser Arg Glu Arg Trp Leu Arg Ala Lys Gln Leu Glu
    610                 615                 620

Ser Leu Arg Arg Thr Arg Leu Gln Gln Gln Lys Cys Val Asn Gly Asn
625                 630                 635                 640

Glu Leu 




<210> 2365
<211> 545
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (205)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (301)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (542)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2365
Met Gln Val Tyr Asp Leu Ala Ala Leu Arg Asp Tyr Trp Ser Tyr Leu
  1               5                  10                  15

Glu Arg Arg Leu Phe Ser Arg Leu Glu Asp Ile Tyr Arg Pro Thr Ile
             20                  25                  30

His Xaa Leu Lys Thr Ser Leu Phe Arg Phe Tyr Leu Val Tyr Thr Ile
         35                  40                  45

Gln Thr Asn Arg Asn Asp Lys Ala Gln Glu Phe Phe Ala Lys Gln Ala
     50                  55                  60

Thr Glu Leu Gln Asn Gln Ala Glu Trp Lys Asp Trp Phe Val Leu Pro
 65                  70                  75                  80

Phe Leu Pro Ser Pro Asp Thr Asn Pro Thr Phe Ala Thr Tyr Phe Ser
                 85                  90                  95

Arg Gln Trp Ala Asp Thr Phe Ile Val Ser Leu His Asn Phe Leu Ser
            100                 105                 110

Val Leu Phe Gln Cys Met Pro Val Pro Val Ile Leu Asn Phe Asp Ala
        115                 120                 125

Glu Cys Gln Arg Thr Asn Gln Val Gln Glu Glu Asn Glu Val Leu Arg
    130                 135                 140

Gln Lys Leu Phe Ala Leu Gln Ala Glu Ile His Arg Leu Lys Lys Glu
145                 150                 155                 160

Glu Gln Gln Pro Glu Glu Glu Glu Ala Leu Val Gln His Lys Leu Pro
                165                 170                 175

Pro Tyr Val Ser Asn Met Asp Arg Leu Gly Asp Ser Glu Leu Ala Met
            180                 185                 190

Val Cys Ser Gln Arg Asn Ala Ser Leu Ser Gln Ser Xaa Arg Val Gly
        195                 200                 205

Phe Leu Ser Ser Leu Leu Pro Gln Ser Lys Lys Ser Pro Ser Arg Leu
    210                 215                 220

Ser Pro Ala Gln Gly Pro Pro Gln Pro Gln Ser Ser Ala Lys Lys Glu
225                 230                 235                 240

Ser Phe Gly Gly Gln Gly Thr Lys Gly Lys Asp Pro Thr Ser Gly Ala
                245                 250                 255

Lys Asp Gly Lys Ser Leu Leu Ser Gly Leu Ala Thr Gly Glu Ser Gly
            260                 265                 270

Trp Ser Gln His Arg Gln Arg Arg Leu Gln Asp His Gly Lys Glu Arg
        275                 280                 285

Lys Glu Leu Phe Ser Thr Thr Thr Ser Gln Cys Ala Xaa Lys Lys Pro
    290                 295                 300

Glu Ala Ser Gly Pro Glu Ala Glu Pro Cys Pro Glu Leu His Thr Glu
305                 310                 315                 320

Pro Val Glu Pro Leu Thr Arg Ala Ser Ser Ala Gly Pro Glu Gly Gly
                325                 330                 335

Gly Val Arg Pro Glu Gln Pro Phe Ile Val Leu Gly Gln Glu Glu Tyr
            340                 345                 350

Gly Glu His His Ser Ser Ile Met His Cys Arg Val Asp Cys Ser Gly
        355                 360                 365

Arg Arg Val Ala Ser Leu Asp Val Asp Gly Val Ile Lys Val Trp Ser
    370                 375                 380

Phe Asn Pro Ile Met Gln Thr Lys Ala Ser Ser Ile Ser Lys Ser Pro
385                 390                 395                 400

Leu Leu Ser Leu Glu Trp Ala Thr Lys Arg Asp Arg Leu Leu Leu Leu
                405                 410                 415

Gly Ser Gly Val Gly Thr Val Arg Leu Tyr Asp Thr Glu Ala Lys Lys
            420                 425                 430

Asn Leu Cys Glu Ile Asn Ile Asn Asp Asn Met Pro Arg Ile Leu Ser
        435                 440                 445

Leu Ala Cys Ser Pro Asn Gly Pro Ser Phe Val Cys Ser Ala Ala Ala
    450                 455                 460

Pro Ser Leu Thr Ser Gln Val Asp Phe Ser Ala Pro Asp Ile Gly Ser
465                 470                 475                 480

Lys Gly Met Asn Gln Val Pro Gly Arg Leu Leu Leu Trp Asp Thr Lys
                485                 490                 495

Thr Met Lys Gln Gln Leu Gln Phe Ser Leu Asp Pro Glu Pro Ile Ala
            500                 505                 510

Ile Asn Cys Thr Ala Phe Asn His Asn Gly Asn Leu Leu Val Thr Gly
        515                 520                 525

Ala Ala Asp Gly Val Ile Arg Leu Phe Asp Ile Ser Ser Xaa Ser Ala
    530                 535                 540

Arg 
545



<210> 2366
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (119)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2366
Met Ala Asp Ile Leu Glu Lys Ile Lys Asn Leu Phe Met Trp Val Gln
  1               5                  10                  15

Pro Glu Ile Thr Gln Lys Leu Tyr Val Ala Leu Trp Ala Ala Phe Leu
             20                  25                  30

Ala Ser Cys Phe Phe Pro Tyr Arg Leu Val Gly Leu Ala Val Gly Leu
         35                  40                  45

Tyr Ala Gly Ile Lys Phe Phe Leu Ile Asp Phe Ile Phe Lys Arg Cys
     50                  55                  60

Pro Arg Leu Arg Ala Lys Tyr Asp Thr Pro Tyr Ile Ile Trp Arg Ser
 65                  70                  75                  80

Leu Pro Thr Asp Pro Gln Leu Lys Glu Arg Ser Ser Xaa Ala Val Phe
                 85                  90                  95

Thr Ala Gly Cys Arg Arg Thr Ser Ser Arg Glu Leu Thr Tyr Pro Ala
            100                 105                 110

Ala Pro Ala Gly Leu Gly Xaa Arg Gly Arg Asp Ala Gly Ser Phe Ser
        115                 120                 125

Thr Ala Pro Arg Arg Ala Xaa Ser 
    130                 135



<210> 2367
<211> 303
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (286)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (288)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2367
Met Ala Met Ala Gln Lys Leu Ser His Leu Leu Pro Ser Leu Arg Gln
  1               5                  10                  15

Val Ile Gln Glu Pro Gln Leu Ser Leu Gln Pro Glu Pro Val Phe Thr
             20                  25                  30

Val Asp Arg Ala Glu Val Pro Pro Leu Phe Trp Lys Pro Tyr Ile Tyr
         35                  40                  45

Ala Gly Tyr Arg Pro Leu His Gln Thr Trp Arg Phe Tyr Phe Arg Thr
     50                  55                  60

Leu Phe Gln Gln His Asn Glu Ala Val Asn Val Trp Thr His Leu Leu
 65                  70                  75                  80

Ala Ala Leu Val Leu Leu Leu Arg Leu Ala Leu Phe Val Glu Thr Val
                 85                  90                  95

Asp Phe Trp Gly Asp Pro His Ala Leu Pro Leu Phe Ile Ile Val Leu
            100                 105                 110

Ala Ser Phe Thr Tyr Leu Ser Phe Ser Ala Leu Ala His Leu Leu Gln
        115                 120                 125

Ala Lys Ser Glu Phe Trp His Tyr Ser Phe Phe Phe Leu Asp Tyr Val
    130                 135                 140

Gly Val Ala Val Tyr Gln Phe Gly Ser Ala Leu Ala His Phe Tyr Tyr
145                 150                 155                 160

Ala Ile Glu Pro Ala Trp His Ala Gln Val Gln Ala Gly Phe Leu Pro
                165                 170                 175

Met Ala Ala Phe Leu Ala Trp Leu Phe Cys Ile Gly Ser Cys Tyr Asn
            180                 185                 190

Lys Tyr Ile Gln Lys Pro Gly Leu Leu Gly Arg His Ala Arg Arg Cys
        195                 200                 205

Pro Xaa Ser Trp Pro Thr His Trp Thr Leu Val Leu Trp Cys Ile Val
    210                 215                 220

Ser Ser Cys Pro Pro Thr Pro Pro Arg Met Ile Gln Leu Phe Ser Thr
225                 230                 235                 240

Thr Ser Ala Arg Trp Ser Ser Phe Cys Trp Leu Leu Pro Ser Ser Leu
                245                 250                 255

Pro Ser Cys Pro Ser Ala Gly Ser Leu Ala Ala Ala Met Ser Ser Gly
            260                 265                 270

Arg Ala Thr Asn Phe Ser Thr Ser Ser Trp Cys Cys Ala Xaa Trp Xaa
        275                 280                 285

Ser Trp Arg Leu Trp His Trp Thr Met Ser Pro Thr Ala His Leu 
    290                 295                 300



<210> 2368
<211> 288
<212> PRT
<213> Homo sapiens

<400> 2368
Met Cys Val Phe Gln Gly Tyr Ser Ser Lys Gly Leu Ile Gln Arg Ser
  1               5                  10                  15

Val Phe Asn Leu Gln Ile Tyr Gly Val Leu Gly Leu Phe Trp Thr Leu
             20                  25                  30

Asn Trp Val Leu Ala Leu Gly Gln Cys Val Leu Ala Gly Ala Phe Ala
         35                  40                  45

Ser Phe Tyr Trp Ala Phe His Lys Pro Gln Asp Ile Pro Thr Phe Pro
     50                  55                  60

Leu Ile Ser Ala Phe Ile Arg Thr Leu Arg Tyr His Thr Gly Ser Leu
 65                  70                  75                  80

Ala Phe Gly Ala Leu Ile Leu Thr Leu Val Gln Ile Ala Arg Val Ile
                 85                  90                  95

Leu Glu Tyr Ile Asp His Lys Leu Arg Gly Val Gln Asn Pro Val Ala
            100                 105                 110

Arg Cys Ile Met Cys Cys Phe Lys Cys Cys Leu Trp Cys Leu Glu Lys
        115                 120                 125

Phe Ile Lys Phe Leu Asn Arg Asn Ala Tyr Ile Met Ile Ala Ile Tyr
    130                 135                 140

Gly Lys Asn Phe Cys Val Ser Ala Lys Asn Ala Phe Met Leu Leu Met
145                 150                 155                 160

Arg Asn Ile Val Arg Val Val Val Leu Asp Lys Val Thr Asp Leu Leu
                165                 170                 175

Leu Phe Phe Gly Lys Leu Leu Val Val Gly Gly Val Gly Val Leu Ser
            180                 185                 190

Phe Phe Phe Phe Ser Gly Arg Ile Pro Gly Leu Gly Lys Asp Phe Lys
        195                 200                 205

Ser Pro His Leu Asn Tyr Tyr Trp Leu Pro Ile Met Thr Ser Ile Leu
    210                 215                 220

Gly Ala Tyr Val Ile Ala Ser Gly Phe Phe Ser Val Phe Gly Met Cys
225                 230                 235                 240

Val Asp Thr Leu Phe Leu Cys Phe Leu Glu Asp Leu Glu Arg Asn Asn
                245                 250                 255

Gly Ser Leu Asp Arg Pro Tyr Tyr Met Ser Lys Ser Leu Leu Lys Ile
            260                 265                 270

Leu Gly Lys Lys Asn Glu Ala Pro Pro Asp Asn Lys Lys Arg Lys Lys
        275                 280                 285






<210> 2369
<211> 199
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (191)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (196)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (199)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2369
Met Ala Ser Ser Leu Leu Ala Gly Glu Arg Leu Val Arg Ala Leu Gly
  1               5                  10                  15

Pro Gly Gly Glu Leu Glu Pro Glu Arg Leu Pro Arg Lys Leu Arg Ala
             20                  25                  30

Glu Leu Glu Ala Ala Leu Gly Lys Lys His Lys Gly Gly Asp Ser Ser
         35                  40                  45

Ser Gly Pro Gln Arg Leu Val Ser Phe Arg Leu Ile Arg Asp Leu His
     50                  55                  60

Gln His Leu Arg Glu Arg Asp Ser Lys Leu Tyr Leu His Glu Leu Leu
 65                  70                  75                  80

Glu Gly Ser Glu Ile Tyr Leu Pro Glu Val Val Lys Pro Pro Arg Asn
                 85                  90                  95

Pro Glu Leu Val Ala Arg Leu Glu Lys Ile Lys Ile Gln Leu Ala Asn
            100                 105                 110

Glu Glu Tyr Lys Arg Ile Thr Arg Asn Val Thr Cys Gln Asp Thr Arg
        115                 120                 125

His Gly Gly Thr Leu Ser Asp Leu Gly Lys Gln Val Arg Ser Leu Lys
    130                 135                 140

Ala Leu Val Ile Thr Ile Phe Xaa Phe Ile Val His Gly Gly Cys Cys
145                 150                 155                 160

Leu Arg Leu His Leu Pro Trp Lys Pro Leu Ser Tyr Arg Asn Gly Ser
                165                 170                 175

Gly Val Leu Asn Asp Ala Leu Trp Gly Gly Trp Pro Leu Met Xaa Gly
            180                 185                 190

Arg Gln Gly Xaa Thr Gly Xaa 
        195



<210> 2370
<211> 533
<212> PRT
<213> Homo sapiens

<400> 2370
Met Ile Lys Leu Ser Glu Lys Gly Val Phe Leu Ala Ser Asn Asn Glu
  1               5                  10                  15

Ile Ile Ala Glu Glu His Phe Thr Gly Glu Ile Lys Lys Glu Glu Ala
             20                  25                  30

Lys Lys Gly Thr Ile Ala Trp Ser Ile Leu Ser Ser His Asn Thr Ser
         35                  40                  45

Gly Asn Met Asp Lys Leu Lys Ile Lys Phe Asp Ser Leu Ala Ser His
     50                  55                  60

Asp Ile Thr Phe Val Gly Ile Val Gln Thr Ala Lys Ala Ser Gly Met
 65                  70                  75                  80

Glu Arg Phe Pro Leu Pro Tyr Val Leu Thr Asn Cys His Asn Ser Leu
                 85                  90                  95

Cys Ala Val Gly Gly Thr Ile Asn Gly Asp Asp His Val Phe Gly Leu
            100                 105                 110

Ser Ala Ala Gln Arg Tyr Gly Gly Ile Phe Val Pro Pro His Ile Ala
        115                 120                 125

Val Ile His Gln Tyr Met Arg Glu Met Met Ala Gly Gly Gly Lys Met
    130                 135                 140

Ile Leu Gly Ser Asp Ser His Thr Arg Tyr Gly Ala Leu Gly Thr Met
145                 150                 155                 160

Ala Val Gly Glu Gly Gly Gly Glu Leu Val Lys Gln Leu Leu Asn Asp
                165                 170                 175

Thr Trp Asp Ile Asp Tyr Pro Gly Val Val Ala Val His Leu Thr Gly
            180                 185                 190

Lys Pro Ala Pro Tyr Val Gly Pro Gln Asp Val Ala Leu Ala Ile Ile
        195                 200                 205

Gly Ala Val Phe Lys Asn Gly Tyr Val Lys Asn Lys Val Met Glu Phe
    210                 215                 220

Val Gly Pro Gly Val Ser Ala Leu Ser Thr Asp Phe Arg Asn Ser Val
225                 230                 235                 240

Asp Val Met Thr Thr Glu Thr Thr Cys Leu Ser Ser Val Trp Gln Thr
                245                 250                 255

Asp Glu Glu Val His Asn Trp Leu Ala Leu His Gly Arg Gly Gln Asp
            260                 265                 270

Tyr Cys Gln Leu Asn Pro Gln Pro Met Ala Tyr Tyr Asp Gly Cys Ile
        275                 280                 285

Ser Val Asp Leu Ser Ala Ile Lys Pro Met Ile Ala Leu Pro Phe His
    290                 295                 300

Pro Ser Asn Val Tyr Glu Ile Asp Thr Leu Asn Gln Asn Leu Thr Asp
305                 310                 315                 320

Ile Leu Arg Glu Ile Glu Ile Glu Ser Glu Arg Val Ala His Gly Lys
                325                 330                 335

Ala Lys Leu Ser Leu Leu Asp Lys Val Glu Asn Gly Arg Leu Lys Val
            340                 345                 350

Gln Gln Gly Ile Ile Ala Gly Cys Ser Gly Gly Asn Tyr Glu Asn Val
        355                 360                 365

Ile Ala Ala Ala Asn Ala Leu Arg Gly Gln Ser Cys Gly Asn Asp Thr
    370                 375                 380

Phe Ser Leu Ala Val Tyr Pro Ser Ser Gln Pro Val Phe Met Asp Leu
385                 390                 395                 400

Ala Lys Lys Gly Val Val Ala Asp Leu Ile Gly Ala Gly Ala Ile Ile
                405                 410                 415

Arg Thr Ala Phe Cys Gly Pro Cys Phe Gly Ala Gly Asp Thr Pro Ile
            420                 425                 430

Asn Asn Gly Leu Ser Ile Arg His Thr Thr Arg Asn Phe Pro Asn Arg
        435                 440                 445

Glu Gly Ser Lys Pro Ala Asn Gly Gln Met Ser Ala Val Ala Leu Met
    450                 455                 460

Asp Ala Arg Ser Ile Ala Ala Thr Ala Ala Asn Gly Gly Tyr Leu Thr
465                 470                 475                 480

Ser Ala Ser Glu Leu Asp Cys Trp Asp Asn Val Pro Glu Tyr Ala Phe
                485                 490                 495

Asp Val Thr Pro Tyr Lys Asn Arg Val Tyr Gln Gly Phe Val Lys Gly
            500                 505                 510

Ala Thr Gln Gln Pro Leu Ile Tyr Gly Gly Ala Arg Tyr Pro Ile Arg
        515                 520                 525

Pro Ile Val Ser Arg 
    530



<210> 2371
<211> 150
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (144)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2371
Met Leu Xaa Glu Xaa Cys Pro Ser Pro Ala Glu Arg Arg Ser Cys Leu
  1               5                  10                  15

Ser Trp Gly Ile Met Trp Val Glu Lys Glu Val Phe Tyr Glu Gln Asn
             20                  25                  30

Gln His Arg Gly Arg Glu Glu Glu Val Phe Arg Gly Cys Arg Glu Pro
         35                  40                  45

Pro Glu Asp Val Gly Thr Val Cys Gln His Gly Gly Gly Ser Xaa Pro
     50                  55                  60

His Gly Gly Thr Leu Leu Arg Val Ala Ser Ser Arg Asp Phe Gln Gly
 65                  70                  75                  80

Leu Gly Phe Ser Val Cys Leu Cys Ser Leu Val Cys Leu Ile Gly Gly
                 85                  90                  95

Gly Pro His Asp Ser Trp Pro Leu Cys Val Ser Leu Leu Ala Val Ser
            100                 105                 110

Asp Leu Gly Pro Lys Gly His Arg Gly Ala Arg Ala Leu Gln Met Gly
        115                 120                 125

Arg Lys Ser Ser Pro Arg Lys Lys Lys Lys Lys Asn Xaa Gly Gly Xaa
    130                 135                 140

Phe Gly Gly Ala Arg Gly 
145                 150



<210> 2372
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2372
Met Lys Ala Gln Asp Cys Arg Arg Gly Ala Val His Gly Ser Arg Thr
  1               5                  10                  15

Arg Leu Cys Pro Leu Gly Glu Gly Val Leu Ser His Glu Val Pro Ile
             20                  25                  30

Arg His Pro Arg Gly Pro Tyr His Pro Phe Leu Ser Glu Gly Val Phe
         35                  40                  45

Gly Ala Trp Gly Arg Leu Ala Val Gln Pro Val Trp Gly Pro Ser Arg
     50                  55                  60

Pro Thr Leu Pro Trp Ala Phe Leu Asp Ser Arg Pro Gly Leu Cys Val
 65                  70                  75                  80

Ala Cys Trp Glu Val Gly Cys Ser Thr Glu Ala Cys Asp Cys Val Pro
                 85                  90                  95

Ala Ala Ser Ser Leu Arg Ile Ser Leu Gly Pro Gly Thr Ser His Val
            100                 105                 110

Pro Ser Cys Gln Arg Arg Glu Val Ser Leu Leu Xaa Glu Ile Phe Asn
        115                 120                 125

Phe Gly Phe Ala Leu Val Leu Ser Phe 
    130                 135



<210> 2373
<211> 157
<212> PRT
<213> Homo sapiens

<400> 2373
Met Gly Ser Leu Val Tyr Leu Arg Gln Gly Ile Glu Asn Ser Pro Tyr
  1               5                  10                  15

Val His Leu Leu Asp Ala Asn Gln Trp Ala Asp Ile Cys Asp Ile Phe
             20                  25                  30

Thr Arg Asp Ala Cys Ala Leu Leu Gly Leu Ser Val Glu Ser Pro Leu
         35                  40                  45

Ser Val Ser Phe Ser Ala Gly Cys Val Ala Leu Pro Ala Leu Ile Asn
     50                  55                  60

Ile Lys Ala Val Ile Glu Gln Arg Gln Cys Thr Gly Val Trp Asn Gln
 65                  70                  75                  80

Lys Asp Glu Leu Pro Ile Glu Val Asp Leu Gly Lys Lys Cys Trp Tyr
                 85                  90                  95

His Ser Ile Phe Ala Cys Pro Ile Leu Arg Gln Gln Thr Thr Asp Asn
            100                 105                 110

Asn Pro Pro Met Lys Leu Val Cys Gly His Ile Ile Ser Arg Asp Ala
        115                 120                 125

Leu Asn Lys Met Phe Asn Gly Ser Lys Leu Lys Cys Pro Tyr Cys Pro
    130                 135                 140

Met Glu Gln Ser Pro Gly Asp Ala Lys Gln Ile Phe Phe 
145                 150                 155



<210> 2374
<211> 135
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2374
Met Arg Arg Gly Trp Lys Met Ala Leu Ser Gly Gly Leu Arg Cys Cys
  1               5                  10                  15

Arg Arg Val Leu Ser Trp Val Pro Val Leu Val Ile Val Leu Val Val
             20                  25                  30

Leu Trp Ser Tyr Tyr Ala Tyr Val Phe Glu Leu Cys Leu Val Thr Val
         35                  40                  45

Leu Ser Pro Ala Glu Lys Val Ile Tyr Leu Ile Leu Tyr His Ala Ile
     50                  55                  60

Phe Val Phe Phe Thr Trp Thr Tyr Trp Lys Ser Ile Phe Thr Leu Pro
 65                  70                  75                  80

Gln Gln Pro Asn Gln Lys Phe His Leu Ser Tyr Thr Asp Lys Glu Arg
                 85                  90                  95

Tyr Glu Asn Glu Glu Arg Pro Glu Val Gln Lys Gln Met Leu Xaa Asp
            100                 105                 110

Met Ala Lys Lys Leu Pro Val Tyr Thr Arg Thr Gly Ser Gly Ala Asp
        115                 120                 125

Xaa Ser Val Thr Xaa Val Ile 
    130                 135



<210> 2375
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2375
Met Leu Leu Cys Met Ser Leu Thr Val Leu Phe Asp Met Val Ile Ala
  1               5                  10                  15

Ile Ser Val Gly Ile Val Leu Ala Ser Leu Leu Phe Met Arg Arg Ile
             20                  25                  30

Ala Arg Met Thr Arg Leu Ala Pro Val Val Val Asp Val Pro Asp Asp
         35                  40                  45

Val Leu Val Leu Arg Val Ile Gly Pro Leu Phe Phe Ala Ala Ala Glu
     50                  55                  60

Gly Leu Phe Thr Asp Leu Glu Ser Arg Leu Glu Gly Lys Arg Ile Val
 65                  70                  75                  80

Ile Leu Lys Trp Asp Ala Val Pro Val Leu Asp Ala Gly Gly Leu Asp
                 85                  90                  95

Ala Phe Gln Arg Phe Val Lys Arg Leu Pro Glu Gly Cys Glu Leu Arg
            100                 105                 110

Val Cys Lys Trp Asn Ser Ser His Cys Ala Leu Trp Leu Ala Leu Ala
        115                 120                 125

Phe Asn Arg Ser Arg Asp Ala Trp Arg Ser Ser Arg Ile Val Ala Arg
    130                 135                 140

Arg Xaa Arg Ile Tyr Lys Tyr Glu Ile Asp Gln Ser Ala Gln Thr Asp
145                 150                 155                 160

Trp Ser Ala Asn Cys Ile Ile Cys 
                165



<210> 2376
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2376
Met Gln Arg Thr Ala Val Ala Ile Thr His Gln Gln Arg Met Lys Gln
  1               5                  10                  15

Gly Ile Leu Arg Leu Trp Arg Asn Trp Leu Leu Trp Leu Leu Ile Leu
             20                  25                  30

Leu Leu Arg Arg Asn Arg Leu Leu Arg Leu Leu Ile Leu Leu Leu Trp
         35                  40                  45

Arg Asn Arg Leu Leu Arg Leu Leu Ile Leu Trp Leu Arg Arg Asn Arg
     50                  55                  60

Leu Leu Trp Leu Leu Ile Leu Arg Leu Arg Arg Asn Trp Leu Leu Arg
 65                  70                  75                  80

Leu Leu Ile Leu Leu Leu Arg Cys Asn Xaa Cys Cys Gly Cys Cys Thr
                 85                  90                  95

Gly Ser Thr Ile Gly Val Asn Asn Gly Ser Cys Gly Pro Ser Ser Ser
            100                 105                 110

Asn Ala Phe Ile Gly Glu Asn Ser Lys Ser Ser Ser Glu Asn Gly Phe
        115                 120                 125

Ala Pro Ala Gly Cys Ser Pro Glu 
    130                 135



<210> 2377
<211> 118
<212> PRT
<213> Homo sapiens

<400> 2377
Met Gln Gly Ala Ala Cys Asp Thr Trp Pro Ala Leu Ser Gln Leu Pro
  1               5                  10                  15

Pro Leu Pro Phe Leu Ser Cys Leu Pro Cys Pro Gln Lys Glu Arg Arg
             20                  25                  30

Gly Leu Thr Tyr His Leu Cys His Ser Thr Trp Ser Gln Asn Pro Lys
         35                  40                  45

Ser Phe Pro Arg Pro His Cys Leu Ala Pro Gln Gly Pro Leu Ser Trp
     50                  55                  60

Val Leu Cys Cys Ala Phe Pro Cys Leu Pro Pro Ala Ala Ser Val Thr
 65                  70                  75                  80

Ala Asp Pro Arg Pro Asn Gly Lys Pro Ser Ala Gln Leu Leu Leu His
                 85                  90                  95

Trp Asn Lys Leu Leu Phe Leu Tyr Val Asp Val Leu Leu Trp Ser Ser
            100                 105                 110

Ser Leu Pro Ile Lys Ser 
        115



<210> 2378
<211> 609
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (604)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (605)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2378
Met Ala Ser Leu Thr Lys Ile Leu Val Ile Gly Leu Lys Pro Ser Leu
  1               5                  10                  15

Lys Val Trp Met Thr Phe Pro Tyr Gly Arg Met Asp Pro Ser Ser Val
             20                  25                  30

Pro Leu Leu Ala Trp His Phe Val Ala Val Gln Asn Tyr Val Asn Pro
         35                  40                  45

Met Leu Ala Phe Cys Arg Gly Asp Val Val His Phe Leu Leu Val Lys
     50                  55                  60

Arg Asp Glu Ser Gly Ala Ile His Val Thr Lys Gln Lys His Leu His
 65                  70                  75                  80

Leu Tyr Tyr Asp Leu Ile Asn Phe Thr Trp Ile Asn Ser Arg Thr Val
                 85                  90                  95

Val Leu Leu Asp Ser Val Glu Lys Leu His Val Ile Asp Arg Gln Thr
            100                 105                 110

Gln Glu Glu Leu Glu Thr Val Glu Ile Ser Glu Val Gln Leu Val Tyr
        115                 120                 125

Asn Ser Ser His Phe Lys Ser Leu Ala Thr Gly Gly Asn Val Ser Gln
    130                 135                 140

Ala Leu Ala Leu Val Gly Glu Lys Ala Cys Tyr Gln Ser Ile Ser Ser
145                 150                 155                 160

Tyr Gly Gly Gln Ile Phe Tyr Leu Gly Thr Lys Ser Val Tyr Val Met
                165                 170                 175

Met Leu Arg Ser Trp Arg Glu Arg Val Asp His Leu Leu Lys Gln Asp
            180                 185                 190

Cys Leu Thr Glu Ala Leu Ala Leu Ala Trp Ser Phe His Glu Gly Lys
        195                 200                 205

Ala Lys Ala Val Val Gly Leu Ser Gly Asp Ala Ser Lys Arg Lys Ala
    210                 215                 220

Ile Gly Ala Asp Arg Met Val Glu Ile Leu Phe His Tyr Ala Asp Arg
225                 230                 235                 240

Ala Leu Lys Lys Cys Pro Asp Gln Gly Lys Ile Gln Val Met Glu Gln
                245                 250                 255

His Phe Gln Asp Met Val Pro Val Ile Val Asp Tyr Cys Leu Leu Leu
            260                 265                 270

Gln Arg Lys Asp Leu Leu Phe Ser Gln Met Tyr Asp Lys Leu Ser Glu
        275                 280                 285

Asn Ser Val Ala Lys Gly Val Phe Leu Glu Cys Leu Glu Pro Tyr Ile
    290                 295                 300

Leu Ser Asp Lys Leu Val Gly Ile Thr Pro Gln Val Met Lys Asp Leu
305                 310                 315                 320

Ile Val His Phe Gln Asp Lys Lys Leu Met Glu Asn Val Glu Ala Leu
                325                 330                 335

Ile Val His Met Asp Ile Thr Ser Leu Asp Ile Gln Gln Val Val Leu
            340                 345                 350

Met Cys Trp Glu Asn Arg Leu Tyr Asp Ala Met Ile Tyr Val Tyr Asn
        355                 360                 365

Arg Gly Met Asn Glu Phe Ile Ser Pro Met Glu Lys Leu Phe Arg Val
    370                 375                 380

Ile Ala Pro Pro Leu Asn Ala Gly Lys Thr Leu Thr Asp Glu Gln Val
385                 390                 395                 400

Val Met Gly Asn Lys Leu Leu Val Tyr Ile Ser Cys Cys Leu Ala Gly
                405                 410                 415

Arg Ala Tyr Pro Leu Gly Asp Ile Pro Glu Asp Leu Val Pro Leu Val
            420                 425                 430

Lys Asn Gln Val Phe Glu Phe Leu Ile Arg Leu His Ser Ala Glu Ala
        435                 440                 445

Ser Pro Glu Glu Glu Ile Tyr Pro Tyr Ile Arg Thr Leu Leu His Phe
    450                 455                 460

Asp Thr Arg Glu Phe Leu Asn Val Leu Ala Leu Thr Phe Glu Asp Phe
465                 470                 475                 480

Lys Asn Asp Lys Gln Ala Val Glu Tyr Gln Gln Arg Ile Val Asp Ile
                485                 490                 495

Leu Leu Lys Val Met Val Glu Asn Ser Asp Phe Thr Pro Ser Gln Val
            500                 505                 510

Gly Cys Leu Phe Thr Phe Leu Ala Arg Gln Leu Ala Lys Pro Asp Asn
        515                 520                 525

Thr Leu Phe Val Asn Arg Thr Leu Phe Asp Gln Val Leu Glu Phe Leu
    530                 535                 540

Cys Ser Pro Asp Asp Asp Ser Arg His Ser Glu Arg Gln Gln Val Leu
545                 550                 555                 560

Leu Glu Leu Leu Gln Ala Gly Gly Ile Val Gln Phe Glu Glu Ser Arg
                565                 570                 575

Leu Ile Arg Met Ala Glu Lys Ala Glu Phe Tyr Gln Ile Cys Glu Phe
            580                 585                 590

Met Tyr Glu Arg Glu His Gln Tyr Asp Gln Asn Xaa Xaa Leu Pro Leu
        595                 600                 605

Thr 




<210> 2379
<211> 129
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2379
Met Met Arg Ala Cys Asn Leu Val Ala Thr Ala Ala Leu Thr Ala Gly
  1               5                  10                  15

Gln Leu Thr Phe Leu Leu Gly Leu Val Gly Leu Pro Leu Leu Ser Pro
             20                  25                  30

Asp Ala Pro Cys Trp Glu Glu Ala Met Ala Ala Ala Phe Gln Leu Ala
         35                  40                  45

Ser Phe Val Leu Val Ile Gly Leu Val Thr Phe Tyr Arg Ile Gly Pro
     50                  55                  60

Tyr Thr Asn Leu Ser Trp Ser Cys Tyr Leu Asn Ile Gly Ala Cys Leu
 65                  70                  75                  80

Leu Ala Thr Leu Ala Ala Xaa Cys Cys Ile Trp Asn Ile Leu His Lys
                 85                  90                  95

Arg Glu Asp Cys Met Ala Pro Arg Val Ile Val Ile Ser Arg Ser Leu
            100                 105                 110

Thr Ala Arg Phe Arg Arg Gly Leu Asp Asn Asp Tyr Val Glu Ser Pro
        115                 120                 125

Cys 




<210> 2380
<211> 149
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2380
Met Ala Gln Ser Asp Thr Cys His Leu Phe Cys Leu Leu Pro Arg Leu
  1               5                  10                  15

Leu Cys Val Asp Trp Leu Gly Ser Ala Leu Lys Ala Ser Arg Thr Leu
             20                  25                  30

Thr Phe Ser Ser Trp Xaa Ser Leu Gly Trp Trp Thr Pro Ser Tyr Ser
         35                  40                  45

Ala Ala Thr Trp Arg Arg Val Leu Cys Ser Glu Cys Gly Arg Arg Asn
     50                  55                  60

Thr Phe Gly Cys Ser His Thr Pro Ser Asp Tyr Ala Pro Val Asn Thr
 65                  70                  75                  80

Ser Glu Tyr Ile Pro Ala Leu Leu Ile Phe Leu Phe Ile Leu Asn Leu
                 85                  90                  95

Phe Leu Cys Glu Ile Asn Gly Gly Arg Asn Leu Arg Ala Thr Ser Ser
            100                 105                 110

Asn Ser Leu Trp Ser Leu Arg Ile Phe Phe Val Phe Tyr Phe Leu Ile
        115                 120                 125

Ser Val Ala Phe Gln Leu Gln Met Leu Lys Phe Val Met Thr Asn Met
    130                 135                 140

Thr Asn Cys His Gly 
145



<210> 2381
<211> 178
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (171)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2381
Met Ile Met Leu Arg Phe Leu Asn Gln Cys Ser Gln Gly Arg Gly Ala
  1               5                  10                  15

Trp Leu Leu Met Ala Phe Thr Ala Leu Ala Leu Glu Leu Thr Ala Leu
             20                  25                  30

Trp Phe Gln His Val Met Leu Leu Lys Pro Cys Val Leu Cys Ile Tyr
         35                  40                  45

Glu Arg Cys Ala Leu Phe Gly Val Leu Gly Ala Ala Leu Ile Gly Ala
     50                  55                  60

Ile Ala Pro Lys Thr Pro Leu Arg Tyr Val Ala Met Val Ile Trp Leu
 65                  70                  75                  80

Tyr Ser Ala Phe Arg Gly Val Gln Leu Thr Tyr Glu His Thr Met Leu
                 85                  90                  95

Gln Leu Tyr Pro Ser Pro Phe Ala Thr Cys Asp Phe Met Val Arg Phe
            100                 105                 110

Pro Glu Trp Leu Pro Leu Asp Lys Trp Val Pro Gln Val Phe Val Ala
        115                 120                 125

Ser Gly Asp Cys Ala Xaa Arg Gln Trp Asp Phe Leu Gly Leu Glu Met
    130                 135                 140

Pro Gln Trp Leu Leu Gly Ile Phe Ile Ala Tyr Leu Ile Val Ala Val
145                 150                 155                 160

Leu Val Val Ile Ser Gln Pro Phe Lys Ala Xaa Xaa Xaa Asp Leu Phe
                165                 170                 175

Gly Arg 




<210> 2382
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (188)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2382
Met Trp Ala Gly Met Trp Gly Ser Thr Lys Gly Leu Gly Leu Ala Leu
  1               5                  10                  15

Leu Ser Ala Trp Glu Gln Leu Gly Leu Ser Val Ala Ile Trp Thr Asp
             20                  25                  30

Leu Phe Leu Ser Cys Leu His Gly Leu Met Leu Val Ala Leu Leu Leu
         35                  40                  45

Val Val Val Thr Trp Arg Val Cys Gln Lys Ser His Cys Phe Arg Leu
     50                  55                  60

Gly Arg Gln Leu Ser Lys Ala Leu Gln Val Asn Cys Val Val Arg Lys
 65                  70                  75                  80

Leu Leu Val Gln Leu Arg Arg Leu Tyr Trp Trp Val Glu Thr Met Thr
                 85                  90                  95

Ala Leu Thr Ser Trp His Leu Ala Tyr Leu Ile Thr Trp Thr Thr Cys
            100                 105                 110

Leu Ala Ser His Leu Leu Gln Ala Ala Phe Glu His Thr Thr Gln Leu
        115                 120                 125

Pro Arg Pro Arg Arg Leu Asn Pro Arg Arg Ser Gln Gly Leu Pro Cys
    130                 135                 140

Cys Pro His Cys Leu Arg Pro Arg Thr Gln Ser Leu Glu Gln Phe Cys
145                 150                 155                 160

Gln Ser Lys Lys Leu Pro Glu Asn Lys Cys Ile Pro Ile Cys Lys Lys
                165                 170                 175

Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Xaa Lys Lys Lys Lys
            180                 185                 190

Lys Lys Lys Lys Lys Lys Lys Lys Leu Glu 
        195                 200



<210> 2383
<211> 155
<212> PRT
<213> Homo sapiens

<400> 2383
Met Leu Glu Asn Leu Asn Leu Ser Leu Phe Ser Leu Ile Asn Ala Thr
  1               5                  10                  15

Pro Asp Ser Ala Pro Trp Met Ile Ser Leu Ala Ile Phe Ile Ala Lys
             20                  25                  30

Asp Leu Ile Thr Val Val Pro Leu Leu Ala Val Val Leu Trp Leu Trp
         35                  40                  45

Gly Leu Thr Ala Gln Arg Gln Leu Val Ile Lys Ile Ala Ile Ala Leu
     50                  55                  60

Ala Val Ser Leu Phe Val Ser Trp Thr Met Gly His Leu Phe Pro His
 65                  70                  75                  80

Asp Arg Pro Phe Val Glu Asn Ile Gly Tyr Asn Phe Leu His His Ala
                 85                  90                  95

Ala Asp Asp Ser Phe Pro Ser Asp His Gly Thr Val Ile Phe Thr Phe
            100                 105                 110

Ala Leu Ala Phe Leu Cys Trp His Arg Leu Trp Ser Gly Ser Leu Leu
        115                 120                 125

Met Val Leu Ala Val Val Ile Ala Trp Ser Arg Val Tyr Leu Gly Val
    130                 135                 140

Gln Tyr Pro Ile Arg Pro Ile Val Ala Thr Gln 
145                 150                 155



<210> 2384
<211> 708
<212> PRT
<213> Homo sapiens

<400> 2384
Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala Ile
  1               5                  10                  15

Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro Arg Leu
             20                  25                  30

Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser Ile Tyr Met
         35                  40                  45

Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu Leu Thr Phe Pro
     50                  55                  60

Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu Leu Gln Thr Asn Asn
 65                  70                  75                  80

Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe Pro Val Asn Leu Thr Gly
                 85                  90                  95

Leu Asp Leu Ser Gln Asn Asn Leu Ser Ser Val Thr Asn Ile Asn Val
            100                 105                 110

Lys Lys Met Pro Gln Leu Leu Ser Val Tyr Leu Glu Glu Asn Lys Leu
        115                 120                 125

Thr Glu Leu Pro Glu Lys Cys Leu Ser Glu Leu Ser Asn Leu Gln Glu
    130                 135                 140

Leu Tyr Ile Asn His Asn Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe
145                 150                 155                 160

Ile Gly Leu His Asn Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu
                165                 170                 175

Gln Met Ile Asn Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile
            180                 185                 190

Leu Met Ile Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe
        195                 200                 205

Lys Pro Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu
    210                 215                 220

Thr Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser
225                 230                 235                 240

Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala Leu
                245                 250                 255

Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile
            260                 265                 270

Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His Leu Lys Glu
        275                 280                 285

Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile Asp Ser Leu Ala
    290                 295                 300

Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu Ala Thr Asn Asn Pro
305                 310                 315                 320

Arg Leu Ser Tyr Ile His Pro Asn Ala Phe Phe Arg Leu Pro Lys Leu
                325                 330                 335

Glu Ser Leu Met Leu Asn Ser Asn Ala Leu Ser Ala Leu Tyr His Gly
            340                 345                 350

Thr Ile Glu Ser Leu Pro Asn Leu Lys Glu Ile Ser Ile His Ser Asn
        355                 360                 365

Pro Ile Arg Cys Asp Cys Val Ile Arg Trp Met Asn Met Asn Lys Thr
    370                 375                 380

Asn Ile Arg Phe Met Glu Pro Asp Ser Leu Phe Cys Val Asp Pro Pro
385                 390                 395                 400

Glu Phe Gln Gly Gln Asn Val Arg Gln Val His Phe Arg Asp Met Met
                405                 410                 415

Glu Ile Cys Leu Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu
            420                 425                 430

Asn Val Glu Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala
        435                 440                 445

Glu Pro Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu
    450                 455                 460

Leu Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr
465                 470                 475                 480

Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr Cys
                485                 490                 495

Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met Ile Lys
            500                 505                 510

Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu Asn Ile Lys
        515                 520                 525

Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser Trp Lys Ala Ser
    530                 535                 540

Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr Ala Phe Val Lys Thr
545                 550                 555                 560

Glu Asn Ser His Ala Ala Gln Ser Ala Arg Ile Pro Ser Asp Val Lys
                565                 570                 575

Val Tyr Asn Leu Thr His Leu Asn Pro Ser Thr Glu Tyr Lys Ile Cys
            580                 585                 590

Ile Asp Ile Pro Thr Ile Tyr Gln Lys Asn Arg Lys Lys Cys Val Asn
        595                 600                 605

Val Thr Thr Lys Gly Leu His Pro Asp Gln Lys Glu Tyr Glu Lys Asn
    610                 615                 620

Asn Thr Thr Thr Leu Met Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile
625                 630                 635                 640

Gly Val Ile Cys Leu Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp
                645                 650                 655

Gly Gly His Ser Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala
            660                 665                 670

Leu Gly Glu Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys
        675                 680                 685

Glu Lys Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro
    690                 695                 700

Thr Asn Met Ser 
705



<210> 2385
<211> 194
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2385
Met Ser Val Cys Cys His Ala Arg Thr Pro Arg Ser Cys Tyr Ala Lys
  1               5                  10                  15

Glu Ser Ser Ser Glu Xaa Tyr Val Pro Asp Val Phe Tyr Lys Asp Val
             20                  25                  30

Asp Lys Phe Gly Asn Glu Ile Thr Gln Leu Ala Arg Pro Leu Pro Val
         35                  40                  45

Glu Tyr Leu Ile Ile Asp Ile Thr Thr Thr Phe Pro Lys Asp Pro Val
     50                  55                  60

Tyr Thr Phe Ser Ile Ser Gln Asn Pro Phe Pro Ile Glu Asn Arg Asp
 65                  70                  75                  80

Val Leu Gly Glu Thr Gln Asp Phe His Ser Leu Ala Thr Tyr Leu Ser
                 85                  90                  95

Gln Asn Xaa Ser Ser Val Phe Leu Asp Thr Ile Ser Asp Phe His Leu
            100                 105                 110

Leu Leu Phe Leu Val Thr Asn Glu Val Met Pro Leu Gln Asp Ser Ile
        115                 120                 125

Ser Leu Leu Leu Glu Ala Val Arg Thr Arg Asn Glu Glu Leu Ala Gln
    130                 135                 140

Thr Trp Lys Arg Ser Glu Gln Trp Ala Thr Ile Glu Gln Leu Cys Xaa
145                 150                 155                 160

Ser Gln Gly Thr Cys Ala Gly Leu Ser Pro Gly Ile Thr Asp Val Tyr
                165                 170                 175

Thr Gln Asp Thr Lys Ile Ser Ser Gly Trp Val Ile Gly Leu Met Val
            180                 185                 190

Lys Gly 




<210> 2386
<211> 108
<212> PRT
<213> Homo sapiens

<400> 2386
Met Ser Cys Pro Leu Ala Leu Arg Ser Ser Pro Val Ile Ser Glu Arg
  1               5                  10                  15

Asp Ser Ala Leu Met Ala Thr Ala Val Thr Arg Asp Cys Ala Ala Pro
             20                  25                  30

Ser Ala Gly Phe Cys Ser Val Val His Val Pro Phe Leu Pro Trp Ser
         35                  40                  45

Gln Gln Arg Arg Cys Gly Ser Gly Leu Gly Cys Val Cys Phe Val Cys
     50                  55                  60

Gly Pro Cys Ser Leu Leu Gly Ser Leu Phe Leu Glu Arg Val Thr Ala
 65                  70                  75                  80

Ser Leu Ser Arg Ser Val Asp Ile Ser Gly Arg Ser Gly Arg Gly His
                 85                  90                  95

Leu Ala Pro Cys Ser Gly Leu Arg Leu Pro Pro Ala 
            100                 105



<210> 2387
<211> 392
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (370)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2387
Met Lys Val His Val Asn Pro Ser Gln Ser Leu Leu Thr Leu Glu Gly
  1               5                  10                  15

Asp Asp Val Glu Thr Phe Asn His Ala Leu Gln His Val Ala Tyr Met
             20                  25                  30

Asn Thr Leu Arg Phe Ala Thr Pro Gly Val Arg Pro Leu Arg Leu Thr
         35                  40                  45

Thr Ala Val Lys Cys Phe Ser Glu Glu Ser Cys Val Ser Ile Pro Glu
     50                  55                  60

Val Glu Gly Tyr Val Val Val Leu Gln Pro Asp Xaa Pro Gln Ile Leu
 65                  70                  75                  80

Leu Ser Gly Thr Xaa His Phe Ala Arg Pro Ala Val Asp Phe Glu Gly
                 85                  90                  95

Thr Asn Gly Val Pro Leu Phe Pro Asp Leu Gln Ile Thr Cys Ser Ile
            100                 105                 110

Ser His Gln Val Glu Ala Lys Lys Asp Glu Ser Trp Gln Gly Thr Val
        115                 120                 125

Thr Asp Thr Arg Met Ser Asp Glu Ile Val His Asn Leu Asp Gly Cys
    130                 135                 140

Glu Ile Ser Leu Val Gly Asp Asp Leu Asp Pro Glu Arg Glu Ser Leu
145                 150                 155                 160

Leu Leu Asp Thr Thr Ser Leu Gln Gln Arg Gly Leu Glu Leu Thr Asn
                165                 170                 175

Thr Ser Ala Tyr Leu Thr Ile Ala Gly Val Glu Ser Ile Thr Val Tyr
            180                 185                 190

Glu Glu Ile Leu Arg Gln Ala Arg Tyr Arg Leu Arg His Gly Ala Ala
        195                 200                 205

Leu Tyr Thr Arg Lys Phe Arg Leu Ser Cys Ser Glu Met Asn Gly Arg
    210                 215                 220

Tyr Ser Ser Asn Glu Phe Ile Val Glu Val Asn Val Leu His Ser Met
225                 230                 235                 240

Asn Arg Val Ala His Pro Ser His Val Leu Ser Ser Gln Gln Phe Leu
                245                 250                 255

His Arg Gly His Gln Pro Pro Pro Glu Met Ala Gly His Ser Leu Ala
            260                 265                 270

Ser Ser His Arg Asn Ser Met Ile Pro Ser Ala Ala Thr Leu Ile Ile
        275                 280                 285

Val Val Cys Val Gly Phe Leu Val Leu Met Val Val Leu Gly Leu Val
    290                 295                 300

Arg Ile His Ser Leu His Arg Arg Val Ser Gly Ala Gly Gly Pro Pro
305                 310                 315                 320

Gly Ala Ser Ser Asp Pro Lys Asp Pro Asp Leu Phe Trp Asp Asp Ser
                325                 330                 335

Ala Leu Thr Ile Ile Val Asn Pro Met Glu Ser Tyr Gln Asn Arg Gln
            340                 345                 350

Ser Cys Val Thr Gly Ala Val Gly Gly Gln Gln Glu Asp Glu Asp Ser
        355                 360                 365

Ser Xaa Ser Glu Val Ala Asp Ser Pro Ser Ser Asp Glu Arg Arg Ile
    370                 375                 380

Ile Glu Thr Pro Pro His Arg Tyr 
385                 390



<210> 2388
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2388
Met Ala Phe Phe Val Phe Glu Thr Leu Thr Ala Gln Arg Leu His Pro
  1               5                  10                  15

Met Gln Tyr Leu Leu Val Gly Leu Ser Leu Val Met Phe Tyr Leu Leu
             20                  25                  30

Leu Leu Ala Leu Ser Glu His Thr Gly Phe Thr Val Ala Trp Ile Ile
         35                  40                  45

Ala Ser Leu Ile Gly Ala Ile Met Asn Gly Ile Tyr Leu Gln Ala Val
     50                  55                  60

Leu Lys Gly Trp Cys Asn Ser Met Leu Phe Thr Leu Ala Leu Leu Leu
 65                  70                  75                  80

Leu Asp Gly Val Met Trp Gly Leu Leu Asn Ser Ala Asp Ser Ala Leu
                 85                  90                  95

Leu Leu Gly Thr Ser Val Leu Val Val Ala Leu Ala Gly Met Met Phe
            100                 105                 110

Val Thr Arg Asn Ile Asp Trp Tyr Ala Phe Ser Leu Pro Lys Met Lys
        115                 120                 125

Ala Ser Lys Glu Val Thr Xaa Asp Asp Glu Leu Arg Ile Trp Lys 
    130                 135                 140



<210> 2389
<211> 117
<212> PRT
<213> Homo sapiens

<400> 2389
Met Ile Phe Leu Thr Val Leu Pro Leu Ala Phe Leu Phe Leu His Ser
  1               5                  10                  15

Gly Phe Tyr His Tyr Ile Ser Phe Ser Cys Leu Phe Ser Leu Ser Leu
             20                  25                  30

Ala Leu Phe Phe Phe Leu Asp Val Ala Thr Phe Arg Arg Pro Gly Gln
         35                  40                  45

Leu Phe Cys Glu Arg Ser Val Leu Phe Asp Met Phe His Phe Gly Phe
     50                  55                  60

Val Ser Leu Phe Leu His Glu Trp Ile Gln Ala Lys His Phe Trp Ala
 65                  70                  75                  80

Gly Leu Phe Ile Val Leu Pro Ser Asp Val Phe Phe Ser Val His His
                 85                  90                  95

Leu Glu Ala Pro Asp Gly Ser Phe Pro Asn Ile Ala Lys Leu Ser Leu
            100                 105                 110

Ile Ile Leu Leu Arg 
        115



<210> 2390
<211> 184
<212> PRT
<213> Homo sapiens

<400> 2390
Met Pro Gln Ser Trp Val Pro Arg Gly Leu Pro His Phe Pro Leu Cys
  1               5                  10                  15

Asp Val Tyr Leu Gln Pro Asp Arg Cys His Gly Lys Thr Pro Ser Val
             20                  25                  30

Ile Ile Leu Ile Arg Thr Val Ser Pro Glu Leu Lys Ser Tyr Ala Leu
         35                  40                  45

Gly Val Leu Phe Leu Leu Leu Arg Leu Leu Gly Phe Ile Pro Pro Pro
     50                  55                  60

Leu Ile Phe Gly Ala Gly Ile Asp Ser Thr Cys Leu Phe Trp Ser Thr
 65                  70                  75                  80

Phe Cys Gly Glu Gln Gly Ala Cys Val Leu Tyr Asp Asn Val Val Tyr
                 85                  90                  95

Arg Tyr Leu Tyr Val Ser Ile Ala Ile Ala Leu Lys Ser Phe Ala Phe
            100                 105                 110

Ile Leu Tyr Thr Thr Thr Trp Gln Cys Leu Arg Lys Asn Tyr Lys Arg
        115                 120                 125

Tyr Ile Lys Asn His Glu Gly Gly Leu Ser Thr Ser Glu Phe Phe Ala
    130                 135                 140

Ser Thr Leu Thr Leu Asp Asn Leu Gly Arg Asp Pro Val Pro Ala Asn
145                 150                 155                 160

Gln Thr His Arg Thr Lys Phe Ile Tyr Asn Leu Glu Asp His Glu Trp
                165                 170                 175

Cys Glu Asn Met Glu Ser Val Leu 
            180



<210> 2391
<211> 219
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2391
Met Ser Glu Gln Glu Ala Gln Ala Pro Gly Gly Arg Gly Leu Pro Pro
  1               5                  10                  15

Asp Met Leu Ala Glu Gln Val Glu Leu Trp Trp Ser Gln Gln Pro Arg
             20                  25                  30

Arg Ser Ala Leu Cys Phe Val Val Ala Val Gly Leu Val Ala Gly Cys
         35                  40                  45

Gly Ala Gly Gly Val Ala Leu Leu Ser Thr Thr Ser Ser Arg Ser Xaa
     50                  55                  60

Glu Trp Arg Leu Ala Thr Gly Thr Val Leu Cys Leu Leu Ala Leu Leu
 65                  70                  75                  80

Val Leu Val Lys Gln Leu Met Ser Ser Ala Val Gln Asp Met Asn Cys
                 85                  90                  95

Ile Arg Gln Ala His His Val Ala Leu Leu Arg Ser Gly Gly Gly Ala
            100                 105                 110

Asp Ala Leu Val Val Leu Leu Ser Gly Leu Val Leu Leu Val Thr Gly
        115                 120                 125

Leu Thr Leu Ala Gly Leu Ala Ala Ala Pro Ala Pro Ala Arg Pro Leu
    130                 135                 140

Ala Ala Met Leu Ser Val Gly Ile Ala Leu Ala Ala Leu Gly Ser Leu
145                 150                 155                 160

Leu Leu Leu Gly Leu Leu Leu Tyr Gln Val Gly Val Ser Gly His Cys
                165                 170                 175

Pro Ser Ile Cys Met Ala Thr Pro Ser Thr His Ser Gly His Gly Gly
            180                 185                 190

His Gly Ser Ile Phe Ser Ile Ser Gly Gln Leu Ser Ala Gly Arg Arg
        195                 200                 205

His Glu Thr Thr Ser Ser Ile Ala Ser Leu Ile 
    210                 215



<210> 2392
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2392
Met Gln Leu Val Leu Cys Leu Ile Lys Met Glu Lys Gly Val Met Ala
  1               5                  10                  15

Leu Phe Leu Gly His Pro Ser Val Met Lys Phe Ile Ile Tyr Phe Pro
             20                  25                  30

Asn Arg Pro Phe Tyr Phe Ile Xaa Ile Leu Xaa Val Ser Val Cys Leu
         35                  40                  45

Cys Val Cys Met Cys Leu Cys Val Cys Thr His Leu Gln Met Pro Val
     50                  55                  60

Val Ala Ala Gly Phe Thr Asn Leu Asn Arg Asn Lys Ser Arg Tyr Pro
 65                  70                  75                  80

Thr Ile Ser Leu Gln Met Arg Val Arg Xaa Ser Leu Ser Lys Ser Gln
                 85                  90                  95

Val Leu Ile Gly 
            100



<210> 2393
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2393
Met Asn His Leu Thr Lys Ser Gly Ile Ile Lys Asp Lys Ala Leu Leu
  1               5                  10                  15

Pro Lys Gly Asn Tyr His Leu Val Lys Asn Tyr Ala Phe His Leu Leu
             20                  25                  30

Ser Tyr Arg Leu Gln Val Ser Pro Arg Ser Ser Ser Gln Ala Leu Gly
         35                  40                  45

Glu Tyr Ser Cys Glu Ile Tyr Leu Gln Leu Glu Ser Ser Tyr Ser Asn
     50                  55                  60

Gln Lys Leu Leu Leu Leu Ser Leu Gln Tyr Cys Ile Cys Thr Val Cys
 65                  70                  75                  80

Ile Pro Leu Gly Pro Tyr Cys Tyr Phe Cys Phe Pro Leu Leu His Arg
                 85                  90                  95

Phe Cys Val Ala Leu Phe Leu Gln Arg Gly Val Val Glu Pro Trp Leu
            100                 105                 110

Tyr Glu 




<210> 2394
<211> 101
<212> PRT
<213> Homo sapiens

<400> 2394
Met Cys Asp Asn Leu Ile Met Leu Arg Thr Leu Met Arg Tyr Ile Val
  1               5                  10                  15

Phe Leu Ser Leu Gln Cys Leu Trp Gly Gln Gly Thr His Ser Ser Cys
             20                  25                  30

Tyr Pro Pro Ser Pro Leu Arg Leu Pro Leu Phe Phe Phe Leu Asp Ile
         35                  40                  45

Lys Leu Gly Ile Ser Asn Trp Pro Val Val Met Gln Ser Cys Phe Ala
     50                  55                  60

Leu Tyr Leu Ala Gly Leu Ile Cys Leu Thr Arg Ser His Glu Ala Ile
 65                  70                  75                  80

Gly Arg Ser Ser Leu Ser Pro Ser Ser Ser Ala Pro Lys Val Val Ala
                 85                  90                  95

Arg Gly Val Pro Ser 
            100



<210> 2395
<211> 230
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (202)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2395
Met Ser Cys Ser Glu Gly Phe Lys Asn Leu Phe Tyr Arg Thr Tyr Met
  1               5                  10                  15

Leu Phe Lys Asn Ala Ser Gly Lys Arg Arg Phe Leu Leu Cys Leu Leu
             20                  25                  30

Leu Phe Thr Val Ile Thr Tyr Phe Phe Val Val Ile Gly Ile Xaa Pro
         35                  40                  45

Ile Phe Ile Leu Tyr Glu Leu Asp Ser Pro Leu Cys Trp Asn Glu Val
     50                  55                  60

Phe Ile Gly Tyr Gly Ser Ala Leu Gly Ser Ala Ser Phe Leu Thr Ser
 65                  70                  75                  80

Phe Leu Gly Ile Trp Leu Phe Ser Tyr Cys Met Glu Asp Ile His Met
                 85                  90                  95

Ala Phe Ile Gly Ile Phe Thr Thr Met Thr Gly Met Ala Met Thr Ala
            100                 105                 110

Phe Ala Ser Thr Thr Leu Met Met Phe Leu Ala Arg Val Pro Phe Leu
        115                 120                 125

Phe Thr Ile Val Pro Phe Ser Val Leu Arg Ser Met Leu Ser Lys Val
    130                 135                 140

Val Arg Ser Thr Glu Gln Gly Thr Leu Phe Ala Cys Ile Ala Phe Leu
145                 150                 155                 160

Glu Thr Leu Gly Gly Val Thr Ala Val Ser Thr Phe Asn Gly Ile Tyr
                165                 170                 175

Ser Ala Thr Val Ala Trp Tyr Pro Gly Phe Thr Phe Leu Leu Ser Ala
            180                 185                 190

Gly Leu Leu Leu Leu Pro Ala Ile Ser Xaa Cys Val Val Lys Cys Thr
        195                 200                 205

Ser Trp Asn Glu Gly Ser Tyr Glu Leu Leu Ile Gln Glu Glu Ser Ser
    210                 215                 220

Glu Asp Ala Ser Asp Arg 
225                 230



<210> 2396
<211> 155
<212> PRT
<213> Homo sapiens

<400> 2396
Met Pro Ile Tyr Phe Ala Ala Val Ile Val Leu Tyr Arg Glu Gln Glu
  1               5                  10                  15

Val Leu Asp Cys Asp Cys Asp Met Ala Ser Val His His Leu Leu Ser
             20                  25                  30

Gln Ile Pro Gln Asp Leu Pro Tyr Glu Thr Leu Ile Ser Arg Ala Gly
         35                  40                  45

Asp Leu Phe Val Gln Phe Pro Pro Ser Glu Leu Ala Arg Glu Ala Ala
     50                  55                  60

Ala Gln Gln Gln Ala Glu Arg Thr Ala Ala Ser Thr Phe Lys Asp Phe
 65                  70                  75                  80

Glu Leu Ala Ser Ala Gln Gln Arg Pro Asp Met Val Leu Arg Gln Arg
                 85                  90                  95

Phe Arg Gly Leu Leu Arg Pro Glu Asp Arg Thr Lys Asp Val Leu Thr
            100                 105                 110

Lys Pro Arg Thr Asn Arg Phe Val Lys Leu Ala Val Met Gly Leu Thr
        115                 120                 125

Val Ala Leu Gly Ala Ala Ala Leu Ala Val Val Lys Ser Ala Leu Glu
    130                 135                 140

Trp Ala Pro Lys Phe Gln Leu Gln Leu Phe Pro 
145                 150                 155



<210> 2397
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2397
Met Ala Ser Gly Ala Ala Arg Trp Leu Val Leu Ala Pro Val Arg Ser
  1               5                  10                  15

Gly Ala Leu Arg Ser Gly Pro Ser Leu Arg Lys Asp Gly Asp Val Ser
             20                  25                  30

Ala Ala Trp Ser Gly Ser Gly Arg Ser Leu Val Pro Ser Arg Ser Val
         35                  40                  45

Ile Val Thr Arg Ser Gly Ala Ile Leu Pro Lys Pro Val Lys Met Ser
     50                  55                  60

Phe Gly Leu Leu Arg Val Phe Ser Ile Val Ile Pro Phe Leu Tyr Val
 65                  70                  75                  80

Gly Thr Leu Ile Ser Lys Asn Phe Ala Ala Leu Leu Glu Glu His Asp
                 85                  90                  95

Ile Phe Val Pro Glu Asp Asp Asp Asp Asp Asp 
            100                 105



<210> 2398
<211> 170
<212> PRT
<213> Homo sapiens

<400> 2398
Met Ala Ile His His Arg Ala Gly Gln Pro Ala Gln Gln Ser Asp Leu
  1               5                  10                  15

Ile Asn Val Ala Gln Leu Thr Ala Gln Tyr Tyr Val Leu Lys Pro Glu
             20                  25                  30

Ala Gly Asn Ala Glu His Ala Val Lys Phe Gly Thr Ser Gly His Arg
         35                  40                  45

Gly Ser Ala Ala Arg His Ser Phe Asn Glu Pro His Ile Leu Ala Ile
     50                  55                  60

Ala Gln Ala Ile Ala Glu Glu Arg Ala Lys Asn Gly Ile Thr Gly Pro
 65                  70                  75                  80

Cys Tyr Val Gly Lys Asp Thr His Ala Leu Ser Glu Pro Ala Phe Ile
                 85                  90                  95

Ser Val Leu Glu Val Leu Ala Ala Asn Gly Val Asp Val Ile Val Gln
            100                 105                 110

Glu Asn Asn Gly Phe Thr Pro Thr Pro Ala Val Ser Asn Ala Ile Leu
        115                 120                 125

Val His Asn Lys Lys Gly Gly Pro Leu Ala Asp Gly Ile Val Ile Thr
    130                 135                 140

Pro Ser His Asn Pro Pro Glu Asp Gly Gly Ile Lys Tyr Asn Pro Pro
145                 150                 155                 160

Asn Gly Gly Pro Ala Asp Thr Asn Val Thr 
                165                 170



<210> 2399
<211> 503
<212> PRT
<213> Homo sapiens

<400> 2399
Met Asn Val Ile Asp His Val Arg Asp Met Ala Ala Ala Gly Leu His
  1               5                  10                  15

Ser Asn Val Arg Leu Leu Ser Ser Leu Leu Leu Thr Met Ser Asn Asn
             20                  25                  30

Asn Pro Glu Leu Phe Ser Pro Pro Gln Lys Tyr Gln Leu Leu Val Tyr
         35                  40                  45

His Ala Asp Ser Leu Phe His Asp Lys Glu Tyr Arg Asn Ala Val Ser
     50                  55                  60

Lys Tyr Thr Met Ala Leu Gln Gln Lys Lys Ala Leu Ser Lys Thr Ser
 65                  70                  75                  80

Lys Val Arg Pro Ser Thr Gly Asn Ser Ala Ser Thr Pro Gln Ser Gln
                 85                  90                  95

Cys Leu Pro Ser Glu Ile Glu Val Lys Tyr Lys Met Ala Glu Cys Tyr
            100                 105                 110

Thr Met Leu Lys Gln Asp Lys Asp Ala Ile Ala Ile Leu Asp Gly Ile
        115                 120                 125

Pro Ser Arg Gln Arg Thr Pro Lys Ile Asn Met Met Leu Ala Asn Leu
    130                 135                 140

Tyr Lys Lys Ala Gly Gln Glu Arg Pro Ser Val Thr Ser Tyr Lys Glu
145                 150                 155                 160

Val Leu Arg Gln Cys Pro Leu Ala Leu Asp Ala Ile Leu Gly Leu Leu
                165                 170                 175

Ser Leu Ser Val Lys Gly Ala Glu Val Ala Ser Met Thr Met Asn Val
            180                 185                 190

Ile Gln Thr Val Pro Asn Leu Asp Trp Leu Ser Val Trp Ile Lys Ala
        195                 200                 205

Tyr Ala Phe Val His Thr Gly Asp Asn Ser Arg Ala Ile Ser Thr Ile
    210                 215                 220

Cys Ser Leu Glu Lys Lys Ser Leu Leu Arg Asp Asn Val Asp Leu Leu
225                 230                 235                 240

Gly Ser Leu Ala Asp Leu Tyr Phe Arg Ala Gly Asp Asn Lys Asn Ser
                245                 250                 255

Val Leu Lys Phe Glu Gln Ala Gln Met Leu Asp Pro Tyr Leu Ile Lys
            260                 265                 270

Gly Met Asp Val Tyr Gly Tyr Leu Leu Ala Arg Glu Gly Arg Leu Glu
        275                 280                 285

Asp Val Glu Asn Leu Gly Cys Arg Leu Phe Asn Ile Ser Asp Gln His
    290                 295                 300

Ala Glu Pro Trp Val Val Ser Gly Cys His Ser Phe Tyr Ser Lys Arg
305                 310                 315                 320

Tyr Ser Arg Ala Leu Tyr Leu Gly Ala Lys Ala Ile Gln Leu Asn Ser
                325                 330                 335

Asn Ser Val Gln Ala Leu Leu Leu Lys Gly Ala Ala Leu Arg Asn Met
            340                 345                 350

Gly Arg Val Gln Glu Ala Ile Ile His Phe Arg Glu Ala Ile Arg Leu
        355                 360                 365

Ala Pro Cys Arg Leu Asp Cys Tyr Glu Gly Leu Ile Glu Cys Tyr Leu
    370                 375                 380

Ala Ser Asn Ser Ile Arg Glu Ala Met Val Met Ala Asn Asn Val Tyr
385                 390                 395                 400

Lys Thr Leu Gly Ala Asn Ala Gln Thr Leu Thr Leu Leu Ala Thr Val
                405                 410                 415

Cys Leu Glu Asp Pro Val Thr Gln Glu Lys Ala Lys Thr Leu Leu Asp
            420                 425                 430

Lys Ala Leu Thr Gln Arg Pro Asp Tyr Ile Lys Ala Val Val Lys Lys
        435                 440                 445

Ala Glu Leu Leu Ser Arg Glu Gln Lys Tyr Glu Asp Gly Ile Ala Leu
    450                 455                 460

Leu Arg Asn Ala Leu Ala Asn Gln Ser Asp Cys Val Leu His Arg Ile
465                 470                 475                 480

Leu Gly Asp Phe Leu Val Ala Val Asn Glu Tyr Gln Glu Ala Met Asp
                485                 490                 495

Gln Tyr Ser Ile Ala Leu Arg 
            500



<210> 2400
<211> 368
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (150)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2400
Met Ser Phe Leu Ile Asp Ser Ser Ile Met Ile Thr Ser Gln Ile Leu
  1               5                  10                  15

Phe Phe Gly Phe Gly Trp Leu Phe Phe Met Arg Gln Leu Phe Lys Asp
             20                  25                  30

Tyr Glu Ile Arg Gln Tyr Val Val Gln Val Ile Phe Ser Val Thr Phe
         35                  40                  45

Ala Phe Ser Cys Thr Met Phe Glu Leu Ile Ile Phe Glu Ile Leu Gly
     50                  55                  60

Val Leu Asn Ser Ser Ser Arg Tyr Phe His Trp Lys Met Asn Leu Cys
 65                  70                  75                  80

Val Ile Leu Leu Ile Leu Val Phe Met Val Pro Phe Tyr Ile Gly Tyr
                 85                  90                  95

Phe Ile Val Ser Asn Ile Arg Leu Leu His Lys Gln Arg Leu Leu Phe
            100                 105                 110

Ser Cys Leu Leu Trp Leu Thr Phe Met Tyr Phe Phe Trp Lys Leu Gly
        115                 120                 125

Asp Pro Phe Pro Ile Leu Ser Pro Lys His Gly Ile Leu Ser Ile Glu
    130                 135                 140

Gln Leu Ile Ser Arg Xaa Gly Val Ile Gly Val Thr Leu Met Ala Leu
145                 150                 155                 160

Leu Ser Gly Phe Gly Ala Val Asn Cys Pro Tyr Thr Tyr Met Ser Tyr
                165                 170                 175

Phe Leu Arg Asn Val Thr Asp Thr Asp Ile Leu Ala Leu Glu Arg Arg
            180                 185                 190

Leu Leu Gln Thr Met Asp Met Ile Ile Ser Lys Lys Lys Arg Met Ala
        195                 200                 205

Met Ala Arg Arg Thr Met Phe Gln Lys Gly Glu Val His Asn Lys Pro
    210                 215                 220

Ser Gly Phe Trp Gly Met Ile Lys Ser Val Thr Thr Ser Ala Ser Gly
225                 230                 235                 240

Ser Glu Asn Leu Thr Leu Ile Gln Gln Glu Val Asp Ala Leu Glu Glu
                245                 250                 255

Leu Ser Arg Gln Leu Phe Leu Glu Thr Ala Asp Leu Tyr Ala Thr Lys
            260                 265                 270

Glu Arg Ile Glu Tyr Ser Lys Thr Phe Lys Gly Lys Tyr Phe Asn Phe
        275                 280                 285

Leu Gly Tyr Phe Phe Ser Ile Tyr Cys Val Trp Lys Ile Phe Met Ala
    290                 295                 300

Thr Ile Asn Ile Val Phe Asp Arg Val Gly Lys Thr Asp Pro Val Thr
305                 310                 315                 320

Arg Gly Ile Glu Ile Thr Val Asn Tyr Leu Gly Ile Gln Phe Asp Val
                325                 330                 335

Lys Phe Trp Ser Gln His Ile Ser Phe Ile Leu Val Gly Ile Ile Ile
            340                 345                 350

Val Thr Ser Ile Arg Gly Leu Leu Ile Thr Leu Thr Lys Val Ile Leu
        355                 360                 365






<210> 2401
<211> 347
<212> PRT
<213> Homo sapiens

<400> 2401
Met Gln Tyr Glu Thr Pro Gly Phe Leu Pro Asn Lys Arg Ile His Arg
  1               5                  10                  15

Ala Met Gly Leu Ala Ala Leu Glu Val Met Gln Ala Val Gln Arg Thr
             20                  25                  30

Trp Thr Asn Ser Lys Val Arg Met Asn Gly Lys Thr Arg Leu Met Gln
         35                  40                  45

Trp Arg Asp Met Phe Asp Ile Ala Val Lys Trp Arg Arg Ile Ala Asp
     50                  55                  60

Pro Asp Gln Pro Val Leu Trp Leu Asp Gln Met Pro Ala Arg Ser Leu
 65                  70                  75                  80

Ser Arg Gly Phe Asn Asn His Ile Asn Leu Ile Arg Gly Gln Val Ile
                 85                  90                  95

Asn Met Arg Tyr Leu Glu Tyr Phe Glu Lys Ile Leu His Phe Ile Lys
            100                 105                 110

Asp Arg Ile Leu Val Tyr His Gly Ala Asn Asn Pro Lys Gly Leu Leu
        115                 120                 125

Glu Val Arg Glu Ala Leu Glu Lys Val His Lys Val Glu Asp Leu Leu
    130                 135                 140

Pro Ile Met Lys Gln Phe Asn Thr Lys Thr Lys Asp Gly Phe Thr Val
145                 150                 155                 160

Asn Thr Lys Val Pro Ser Leu Lys Asp Gln Gly Lys Glu Tyr Asp Gly
                165                 170                 175

Phe Thr Ile Thr Ile Thr Gly Asp Lys Val Gly Asn Ile Leu Phe Ser
            180                 185                 190

Val Glu Thr Gln Thr Thr Glu Glu Arg Thr Gln Leu Tyr His Ala Glu
        195                 200                 205

Ile Asp Ala Leu Tyr Lys Asp Leu Thr Ala Lys Gly Lys Val Leu Ile
    210                 215                 220

Leu Ser Ser Glu Phe Gly Glu Ala Asp Ala Val Cys Asn Leu Ile Leu
225                 230                 235                 240

Ser Leu Val Tyr Tyr Phe Tyr Asn Leu Met Pro Leu Ser Arg Gly Ser
                245                 250                 255

Ser Val Ile Ala Tyr Ser Val Ile Val Gly Ala Leu Met Ala Ser Gly
            260                 265                 270

Lys Glu Val Ala Gly Lys Ile Pro Lys Gly Lys Leu Val Asp Phe Glu
        275                 280                 285

Ala Met Thr Ala Pro Gly Ser Glu Ala Phe Ser Lys Val Ala Lys Ser
    290                 295                 300

Trp Met Asn Leu Lys Ser Ile Ser Pro Ser Tyr Lys Thr Leu Pro Ser
305                 310                 315                 320

Val Ser Glu Thr Phe Pro Thr Leu Arg Ser Met Ile Glu Val Leu Asn
                325                 330                 335

Thr Asp Ser Ser Pro Arg Cys Leu Lys Lys Leu 
            340                 345



<210> 2402
<211> 563
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (538)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2402
Met Val Ser Thr Val Glu Cys Ala Leu Lys His Val Ser Asp Trp Leu
  1               5                  10                  15

Asp Glu Thr Asn Lys Gly Thr Lys Thr Glu Gly Glu Thr Glu Val Lys
             20                  25                  30

Lys Asp Glu Ala Gly Glu Asn Tyr Ser Lys Asp Gln Gly Gly Arg Thr
         35                  40                  45

Leu Cys Gly Val Met Arg Ile Gly Leu Val Ala Lys Gly Leu Leu Ile
     50                  55                  60

Lys Asp Asp Met Asp Leu Glu Leu Val Leu Met Cys Lys Asp Lys Pro
 65                  70                  75                  80

Thr Glu Thr Leu Leu Asn Thr Val Lys Asp Asn Leu Pro Ile Xaa Ile
                 85                  90                  95

Gln Lys Leu Thr Glu Glu Lys Tyr Gln Val Glu Gln Cys Val Asn Glu
            100                 105                 110

Ala Ser Ile Ile Ile Arg Asn Thr Lys Glu Pro Thr Leu Thr Leu Lys
        115                 120                 125

Val Ile Leu Thr Ser Pro Leu Ile Arg Asp Glu Leu Glu Lys Lys Asp
    130                 135                 140

Gly Glu Asn Val Ser Met Lys Asp Pro Pro Asp Leu Leu Asp Arg Gln
145                 150                 155                 160

Lys Cys Leu Asn Ala Leu Ala Ser Leu Arg His Ala Lys Trp Phe Gln
                165                 170                 175

Ala Arg Ala Asn Gly Leu Lys Ser Cys Val Ile Val Leu Arg Ile Leu
            180                 185                 190

Arg Asp Leu Cys Asn Arg Val Pro Thr Trp Ala Pro Leu Lys Gly Trp
        195                 200                 205

Pro Leu Glu Leu Ile Cys Glu Lys Ser Ile Gly Thr Cys Asn Arg Pro
    210                 215                 220

Leu Gly Ala Gly Glu Ala Leu Arg Arg Val Met Glu Cys Leu Ala Ser
225                 230                 235                 240

Gly Ile Leu Leu Pro Gly Gly Pro Gly Leu His Asp Pro Cys Glu Arg
                245                 250                 255

Asp Pro Thr Asp Ala Leu Ser Tyr Met Thr Ile Gln Gln Lys Glu Asp
            260                 265                 270

Ile Thr His Ser Ala Gln His Ala Leu Arg Leu Ser Ala Phe Gly Gln
        275                 280                 285

Ile Tyr Lys Val Leu Glu Met Asp Pro Leu Pro Ser Ser Lys Pro Phe
    290                 295                 300

Gln Lys Tyr Ser Trp Ser Val Thr Asp Lys Glu Gly Ala Gly Ser Ser
305                 310                 315                 320

Ala Leu Lys Arg Pro Phe Glu Asp Gly Leu Gly Asp Asp Lys Asp Pro
                325                 330                 335

Asn Lys Lys Met Lys Arg Asn Leu Arg Lys Ile Leu Asp Ser Lys Ala
            340                 345                 350

Ile Asp Leu Met Asn Ala Leu Met Arg Leu Asn Gln Ile Arg Pro Gly
        355                 360                 365

Leu Gln Tyr Lys Leu Leu Ser Gln Ser Gly Pro Val His Ala Pro Val
    370                 375                 380

Phe Thr Met Ser Val Asp Val Asp Gly Thr Thr Tyr Glu Ala Ser Gly
385                 390                 395                 400

Pro Ser Lys Lys Thr Ala Lys Leu His Val Ala Val Lys Val Leu Gln
                405                 410                 415

Ala Met Gly Tyr Pro Thr Gly Phe Asp Ala Asp Ile Glu Cys Met Ser
            420                 425                 430

Ser Asp Glu Lys Ser Asp Asn Glu Ser Lys Asn Glu Thr Val Ser Ser
        435                 440                 445

Asn Ser Ser Asn Asn Thr Gly Asn Ser Thr Thr Glu Thr Ser Ser Thr
    450                 455                 460

Leu Glu Val Arg Thr Gln Gly Pro Ile Leu Thr Ala Ser Gly Lys Asn
465                 470                 475                 480

Pro Val Met Glu Leu Asn Glu Lys Arg Arg Gly Leu Lys Tyr Glu Leu
                485                 490                 495

Ile Ser Glu Thr Gly Gly Ser His Asp Lys Arg Phe Val Met Glu Val
            500                 505                 510

Glu Val Asp Gly Gln Lys Phe Arg Gly Ala Gly Pro Asn Lys Lys Val
        515                 520                 525

Ala Lys Ala Ser Ala Ala Leu Ala Ala Xaa Gly Arg Asn Cys Phe Leu
    530                 535                 540

Asp Pro Met Arg Gln Ile Ile Arg Lys Arg Arg Leu Ser Leu Arg Gln
545                 550                 555                 560

Arg Ala Leu 




<210> 2403
<211> 434
<212> PRT
<213> Homo sapiens

<400> 2403
Met Gln Glu Ser Gly Cys Arg Leu Glu His Pro Ser Ala Thr Lys Phe
  1               5                  10                  15

Arg Asn His Val Met Glu Gly Asp Trp Asp Lys Ala Glu Asn Asp Leu
             20                  25                  30

Asn Glu Leu Lys Pro Leu Val His Ser Pro His Ala Ile Val Val Arg
         35                  40                  45

Gly Ala Leu Glu Ile Ser Gln Thr Leu Leu Gly Ile Ile Val Arg Met
     50                  55                  60

Lys Phe Leu Leu Leu Gln Gln Lys Tyr Leu Glu Tyr Leu Glu Asp Gly
 65                  70                  75                  80

Lys Val Leu Glu Ala Leu Gln Val Leu Arg Cys Glu Leu Thr Pro Leu
                 85                  90                  95

Lys Tyr Asn Thr Glu Arg Ile His Val Leu Ser Gly Tyr Leu Met Cys
            100                 105                 110

Ser His Ala Glu Asp Leu Arg Ala Lys Ala Glu Trp Glu Gly Lys Gly
        115                 120                 125

Thr Ala Ser Arg Ser Lys Leu Leu Asp Lys Leu Gln Thr Tyr Leu Pro
    130                 135                 140

Pro Ser Val Met Leu Pro Pro Arg Arg Leu Gln Thr Leu Leu Arg Gln
145                 150                 155                 160

Ala Val Glu Leu Gln Arg Asp Arg Cys Leu Tyr His Asn Thr Lys Leu
                165                 170                 175

Asp Asn Asn Leu Asp Ser Val Ser Leu Leu Ile Asp His Val Cys Ser
            180                 185                 190

Arg Arg Gln Phe Pro Cys Tyr Thr Gln Gln Ile Leu Thr Glu His Cys
        195                 200                 205

Asn Glu Val Trp Phe Cys Lys Phe Ser Asn Asp Gly Thr Lys Leu Ala
    210                 215                 220

Thr Gly Ser Lys Asp Thr Thr Val Ile Ile Trp Gln Val Asp Pro Asp
225                 230                 235                 240

Thr His Leu Leu Lys Leu Leu Lys Thr Leu Glu Gly His Ala Tyr Gly
                245                 250                 255

Val Ser Tyr Ile Ala Trp Ser Pro Asp Asp Asn Tyr Leu Val Ala Cys
            260                 265                 270

Gly Pro Asp Asp Cys Ser Glu Leu Trp Leu Trp Asn Val Gln Thr Gly
        275                 280                 285

Glu Leu Arg Thr Lys Met Ser Gln Ser His Glu Asp Ser Leu Thr Ser
    290                 295                 300

Val Ala Trp Asn Pro Asp Gly Lys Arg Phe Val Thr Gly Gly Gln Arg
305                 310                 315                 320

Gly Gln Phe Tyr Gln Cys Asp Leu Asp Gly Asn Leu Leu Asp Ser Trp
                325                 330                 335

Glu Gly Val Arg Val Gln Cys Leu Trp Cys Leu Ser Asp Gly Lys Thr
            340                 345                 350

Val Leu Ala Ser Asp Thr His Gln Arg Ile Arg Gly Tyr Asn Phe Glu
        355                 360                 365

Asp Leu Thr Asp Arg Asn Ile Val Gln Glu Asp His Pro Ile Met Ser
    370                 375                 380

Phe Thr Ile Ser Lys Asn Gly Arg Leu Ala Leu Leu Asn Val Ala Thr
385                 390                 395                 400

Gln Gly Val His Leu Trp Asp Leu Gln Asp Arg Val Leu Val Arg Lys
                405                 410                 415

Tyr Gln Gly Val Thr Gln Gly Phe Tyr Thr Ile His Cys Met Phe Trp
            420                 425                 430

Arg Pro 




<210> 2404
<211> 318
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (32)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2404
Met Glu Thr Arg Tyr Asn Leu Lys Ser Pro Ala Val Lys Arg Leu Met
  1               5                  10                  15

Lys Glu Ala Ala Glu Leu Lys Asp Pro Thr Asp His Tyr His Ala Xaa
             20                  25                  30

Xaa Leu Glu Asp Asn Leu Phe Glu Trp His Phe Thr Val Arg Gly Pro
         35                  40                  45

Pro Asp Ser Asp Phe Asp Gly Gly Val Tyr His Gly Arg Ile Val Leu
     50                  55                  60

Pro Pro Glu Tyr Pro Met Lys Pro Pro Ser Ile Ile Leu Leu Thr Ala
 65                  70                  75                  80

Asn Gly Arg Phe Glu Val Gly Lys Lys Ile Cys Leu Ser Ile Ser Gly
                 85                  90                  95

His His Pro Glu Thr Trp Gln Pro Ser Trp Ser Ile Arg Thr Ala Leu
            100                 105                 110

Leu Ala Ile Ile Gly Phe Met Pro Thr Lys Gly Glu Gly Ala Ile Gly
        115                 120                 125

Ser Leu Asp Tyr Thr Pro Glu Glu Arg Arg Ala Leu Ala Lys Lys Ser
    130                 135                 140

Gln Asp Phe Cys Cys Glu Gly Cys Gly Ser Ala Met Lys Asp Val Leu
145                 150                 155                 160

Leu Pro Leu Lys Ser Gly Ser Asp Ser Ser Gln Ala Asp Gln Glu Ala
                165                 170                 175

Lys Glu Leu Ala Arg Gln Ile Ser Phe Lys Ala Glu Val Asn Ser Ser
            180                 185                 190

Gly Lys Thr Ile Ser Glu Ser Asp Leu Asn His Ser Phe Ser Leu Thr
        195                 200                 205

Asp Leu Gln Asp Asp Ile Pro Thr Thr Phe Gln Gly Ala Thr Ala Ser
    210                 215                 220

Thr Ser Tyr Gly Leu Gln Asn Ser Ser Ala Ala Ser Phe His Gln Pro
225                 230                 235                 240

Thr Gln Pro Val Ala Lys Asn Thr Ser Met Ser Pro Arg Gln Arg Arg
                245                 250                 255

Ala Gln Gln Gln Ser Gln Arg Arg Leu Ser Thr Ser Pro Asp Val Ile
            260                 265                 270

Gln Gly His Gln Pro Arg Asp Asn His Thr Asp His Gly Gly Ser Ala
        275                 280                 285

Val Leu Ile Val Ile Leu Thr Leu Ala Leu Ala Ala Leu Ile Phe Arg
    290                 295                 300

Arg Ile Tyr Leu Ala Asn Glu Tyr Ile Phe Asp Phe Glu Leu 
305                 310                 315



<210> 2405
<211> 469
<212> PRT
<213> Homo sapiens

<400> 2405
Met Arg Gln Ile Ser Gln Asp Phe Ser Glu Leu Ser Thr Gln Leu Thr
  1               5                  10                  15

Gly Val Ala Arg Asp Leu Gln Glu Glu Met Leu Pro Gly Ser Ser Glu
             20                  25                  30

Asp Trp Leu Glu Pro Pro Gly Ala Val Gly Arg Pro Ala Thr Glu Pro
         35                  40                  45

Pro Arg Glu Gly Thr Thr Glu Gly Asp Glu Glu Asp Ala Thr Glu Ala
     50                  55                  60

Trp Arg Leu His Gln Lys His Val Phe Val Leu Ser Glu Ala Gly Lys
 65                  70                  75                  80

Pro Val Tyr Ser Arg Tyr Gly Ser Glu Glu Ala Leu Ser Ser Thr Met
                 85                  90                  95

Gly Val Met Val Ala Leu Val Ser Phe Leu Glu Ala Asp Lys Asn Ala
            100                 105                 110

Ile Arg Ser Ile His Ala Asp Gly Tyr Lys Val Val Phe Val Arg Arg
        115                 120                 125

Ser Pro Leu Val Leu Val Ala Val Ala Arg Thr Arg Gln Ser Ala Gln
    130                 135                 140

Glu Leu Ala Gln Glu Leu Leu Tyr Ile Tyr Tyr Gln Ile Leu Ser Leu
145                 150                 155                 160

Leu Thr Gly Ala Gln Leu Ser His Ile Phe Gln Gln Lys Gln Asn Tyr
                165                 170                 175

Asp Leu Arg Arg Leu Leu Ser Gly Ser Glu Arg Ile Thr Asp Asn Leu
            180                 185                 190

Leu Gln Leu Met Ala Arg Asp Pro Ser Phe Leu Met Gly Ala Ala Arg
        195                 200                 205

Cys Leu Pro Leu Ala Ala Ala Val Arg Asp Thr Val Ser Ala Ser Leu
    210                 215                 220

Gln Gln Ala Arg Ala Arg Ser Leu Val Phe Ser Ile Leu Leu Ala Arg
225                 230                 235                 240

Asn Gln Leu Val Ala Leu Val Arg Arg Lys Asp Gln Phe Leu His Pro
                245                 250                 255

Ile Asp Leu His Leu Leu Phe Asn Leu Ile Ser Ser Ser Ser Ser Phe
            260                 265                 270

Arg Glu Gly Glu Ala Trp Thr Pro Val Cys Leu Pro Lys Phe Asn Ala
        275                 280                 285

Ala Gly Phe Phe His Ala His Ile Ser Tyr Leu Glu Pro Asp Thr Asp
    290                 295                 300

Leu Cys Leu Leu Leu Val Ser Thr Asp Arg Glu Asp Phe Phe Ala Val
305                 310                 315                 320

Ser Asp Cys Arg Arg Arg Phe Gln Glu Arg Leu Arg Lys Arg Gly Ala
                325                 330                 335

His Leu Ala Leu Arg Glu Ala Leu Arg Thr Pro Tyr Tyr Ser Val Ala
            340                 345                 350

Gln Val Gly Ile Pro Asp Leu Arg His Phe Leu Tyr Lys Ser Lys Ser
        355                 360                 365

Ser Gly Leu Phe Thr Ser Pro Glu Ile Glu Ala Pro Tyr Thr Ser Glu
    370                 375                 380

Glu Glu Gln Glu Arg Leu Leu Gly Leu Tyr Gln Tyr Leu His Ser Arg
385                 390                 395                 400

Ala His Asn Ala Ser Arg Pro Leu Lys Thr Ile Tyr Tyr Thr Gly Pro
                405                 410                 415

Asn Glu Asn Leu Leu Ala Trp Val Thr Gly Ala Phe Glu Leu Tyr Met
            420                 425                 430

Cys Tyr Ser Pro Leu Gly Thr Lys Ala Ser Ala Val Ser Ala Ile His
        435                 440                 445

Lys Leu Met Arg Trp Ile Arg Lys Glu Glu Asp Arg Leu Phe Ile Leu
    450                 455                 460

Thr Pro Leu Thr Tyr 
465



<210> 2406
<211> 189
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2406
Met Thr Arg Asn Thr Ser Thr Ala Pro Ala His Trp Ser Gly Ser Pro
  1               5                  10                  15

Trp Xaa Thr Asn Ile Ala Tyr Trp Leu His Pro Arg Thr Ser Ala Gln
             20                  25                  30

Ile His Leu Leu Gly Asn Ile Val Ile Trp Val Ser Gly Ser Leu Ala
         35                  40                  45

Leu Ala Ile Tyr Ala Leu Leu Ser Leu Trp Tyr Leu Leu Arg Arg Arg
     50                  55                  60

Arg Asn Val His Asp Leu Pro Gln Asp Ala Trp Leu Arg Trp Val Leu
 65                  70                  75                  80

Ala Gly Ala Leu Cys Ala Gly Gly Trp Ala Val Asn Tyr Leu Pro Phe
                 85                  90                  95

Phe Leu Met Glu Lys Thr Leu Phe Leu Tyr His Tyr Leu Pro Xaa Leu
            100                 105                 110

His Leu Pro Asn Pro Ser Ala Pro Cys Gly Pro Ala Ala His Gln Arg
        115                 120                 125

Pro Pro Val Gln Val Pro Ala Pro Glu Glu Ile Phe Ser Ala Leu Val
    130                 135                 140

Val Ala Trp Tyr Ser Ser Ala Cys His Val Ser Asn Thr Leu Arg Pro
145                 150                 155                 160

Leu Thr Tyr Gly Asp Lys Ser Leu Ser Pro His Glu Leu Lys Ala Leu
                165                 170                 175

Arg Trp Lys Asp Ser Trp Asp Ile Leu Ile Arg Lys His 
            180                 185



<210> 2407
<211> 105
<212> PRT
<213> Homo sapiens

<400> 2407
Met Phe Ile Ser Asn Leu Phe Leu Ile Leu Cys Phe Leu Phe Arg Pro
  1               5                  10                  15

Thr Lys Thr Thr Val Met Tyr Leu Ile His Leu Tyr Gln Val Leu Lys
             20                  25                  30

Tyr Leu Asp Lys Ser Lys Tyr Phe Val Phe Ser Phe Phe Leu Leu Ser
         35                  40                  45

Ile Leu Leu Thr Thr Val Lys Arg Cys Ser Ile Leu Ile Trp Ser Val
     50                  55                  60

Leu Arg Arg Lys Thr Met Lys Ala Glu Leu Val Cys Ala Thr Gln Ser
 65                  70                  75                  80

Lys Pro Leu Leu Phe Phe Trp Lys Asp Gly Val Met Phe Phe Lys Asp
                 85                  90                  95

Ser Asn Lys Tyr Pro Ala Val Ile Ser 
            100                 105



<210> 2408
<211> 455
<212> PRT
<213> Homo sapiens

<400> 2408
Met Thr Thr Met Ala Ala Ala Thr Leu Leu Arg Ala Thr Pro His Phe
  1               5                  10                  15

Ser Gly Leu Ala Ala Gly Arg Thr Phe Leu Leu Gln Gly Leu Leu Arg
             20                  25                  30

Leu Leu Lys Ala Pro Ala Leu Pro Leu Leu Cys Arg Gly Leu Ala Val
         35                  40                  45

Glu Ala Lys Lys Thr Tyr Val Arg Asp Lys Pro His Val Asn Val Gly
     50                  55                  60

Thr Ile Gly His Val Asp His Gly Lys Thr Thr Leu Thr Ala Ala Ile
 65                  70                  75                  80

Thr Lys Ile Leu Ala Glu Gly Gly Gly Ala Lys Phe Lys Lys Tyr Glu
                 85                  90                  95

Glu Ile Asp Asn Ala Pro Glu Glu Arg Ala Arg Gly Ile Thr Ile Asn
            100                 105                 110

Ala Ala His Val Glu Tyr Ser Thr Ala Ala Arg His Tyr Ala His Thr
        115                 120                 125

Asp Cys Pro Gly His Ala Asp Tyr Val Lys Asn Met Ile Thr Gly Thr
    130                 135                 140

Ala Pro Leu Asp Gly Cys Ile Leu Val Val Ala Ala Asn Asp Gly Pro
145                 150                 155                 160

Met Pro Gln Thr Arg Glu His Leu Leu Leu Ala Arg Gln Ile Gly Val
                165                 170                 175

Glu His Val Val Val Tyr Val Asn Lys Ala Asp Ala Val Gln Asp Ser
            180                 185                 190

Glu Met Val Glu Leu Val Glu Leu Glu Ile Arg Glu Leu Leu Thr Glu
        195                 200                 205

Phe Gly Tyr Lys Gly Glu Glu Thr Pro Val Ile Val Gly Ser Ala Leu
    210                 215                 220

Cys Ala Leu Glu Gly Arg Asp Pro Glu Leu Gly Leu Lys Ser Val Gln
225                 230                 235                 240

Lys Leu Leu Asp Ala Val Asp Thr Tyr Ile Pro Val Pro Ala Arg Asp
                245                 250                 255

Leu Glu Lys Pro Phe Leu Leu Pro Val Glu Ala Val Tyr Ser Val Pro
            260                 265                 270

Gly Arg Gly Thr Val Val Thr Gly Thr Leu Glu Arg Gly Ile Leu Lys
        275                 280                 285

Lys Gly Asp Glu Cys Glu Leu Leu Gly His Ser Lys Asn Ile Arg Thr
    290                 295                 300

Val Val Thr Gly Ile Glu Met Phe His Lys Ser Leu Glu Arg Ala Glu
305                 310                 315                 320

Ala Gly Asp Asn Leu Gly Ala Leu Val Arg Gly Leu Lys Arg Glu Asp
                325                 330                 335

Leu Arg Arg Gly Leu Val Met Val Lys Pro Gly Ser Ile Lys Pro His
            340                 345                 350

Gln Lys Val Glu Ala Gln Val Tyr Ile Leu Ser Lys Glu Glu Gly Gly
        355                 360                 365

Arg His Lys Pro Phe Val Ser His Phe Met Pro Val Met Phe Ser Leu
    370                 375                 380

Thr Trp Asp Met Ala Cys Arg Ile Ile Leu Pro Pro Glu Lys Glu Leu
385                 390                 395                 400

Ala Met Pro Gly Glu Asp Leu Lys Phe Asn Leu Ile Leu Arg Gln Pro
                405                 410                 415

Met Ile Leu Glu Lys Gly Gln Arg Phe Thr Leu Arg Asp Gly Asn Arg
            420                 425                 430

Thr Ile Gly Thr Gly Leu Val Thr Asn Thr Leu Ala Met Thr Glu Glu
        435                 440                 445

Glu Lys Asn Ile Lys Trp Gly 
    450                 455



<210> 2409
<211> 492
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (397)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (398)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (399)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2409
Met Gly Gly Arg Arg Gly Pro Asn Arg Thr Ser Tyr Cys Arg Asn Pro
  1               5                  10                  15

Leu Cys Glu Pro Gly Ser Ser Gly Gly Ser Ser Gly Ser His Thr Ser
             20                  25                  30

Ser Ala Ser Val Thr Ser Val Arg Ser Arg Thr Arg Ser Ser Ser Gly
         35                  40                  45

Thr Gly Leu Ser Ser Pro Pro Leu Ala Thr Gln Thr Val Val Pro Leu
     50                  55                  60

Gln His Cys Lys Ile Pro Glu Leu Pro Val Gln Ala Ser Ile Leu Phe
 65                  70                  75                  80

Glu Leu Gln Leu Phe Phe Cys Gln Leu Ile Ala Leu Phe Val His Tyr
                 85                  90                  95

Ile Asn Ile Tyr Lys Thr Val Trp Trp Tyr Pro Pro Ser His Pro Pro
            100                 105                 110

Ser His Thr Ser Leu Asn Phe His Leu Ile Asp Phe Asn Leu Leu Met
        115                 120                 125

Val Thr Thr Ile Val Leu Gly Arg Arg Phe Ile Gly Ser Ile Val Lys
    130                 135                 140

Glu Ala Ser Gln Arg Gly Lys Val Ser Leu Phe Arg Ser Ile Leu Leu
145                 150                 155                 160

Phe Leu Thr Arg Phe Thr Val Leu Thr Ala Thr Gly Trp Ser Leu Cys
                165                 170                 175

Arg Ser Leu Ile His Leu Phe Arg Thr Tyr Ser Phe Leu Asn Leu Leu
            180                 185                 190

Phe Leu Cys Tyr Pro Phe Gly Met Tyr Ile Pro Phe Leu Gln Leu Asn
        195                 200                 205

Cys Asp Leu Arg Lys Thr Ser Leu Phe Asn His Met Ala Ser Met Gly
    210                 215                 220

Pro Arg Glu Ala Val Ser Gly Leu Ala Lys Ser Arg Asp Tyr Leu Leu
225                 230                 235                 240

Thr Leu Arg Glu Thr Trp Lys Gln His Thr Arg Gln Leu Tyr Gly Pro
                245                 250                 255

Asp Ala Met Pro Thr His Ala Cys Cys Leu Ser Pro Ser Leu Ile Arg
            260                 265                 270

Ser Glu Val Glu Phe Leu Lys Met Asp Phe Asn Trp Arg Met Lys Glu
        275                 280                 285

Val Leu Val Ser Ser Met Leu Ser Ala Tyr Tyr Val Ala Phe Val Pro
    290                 295                 300

Val Trp Phe Val Lys Asn Thr His Tyr Tyr Asp Lys Arg Trp Ser Cys
305                 310                 315                 320

Glu Leu Phe Leu Leu Val Ser Ile Ser Thr Ser Val Ile Leu Met Gln
                325                 330                 335

His Leu Leu Pro Ala Ser Tyr Cys Asp Leu Leu His Lys Ala Ala Ala
            340                 345                 350

His Leu Gly Cys Trp Gln Lys Val Asp Pro Ala Leu Cys Ser Asn Val
        355                 360                 365

Leu Gln His Pro Trp Thr Glu Glu Cys Met Trp Pro Gln Gly Val Leu
    370                 375                 380

Val Lys His Ser Lys Asn Val Tyr Lys Ala Val Gly Xaa Xaa Xaa Val
385                 390                 395                 400

Ala Ile Pro Ser Asp Val Ser His Phe Arg Phe His Phe Phe Phe Ser
                405                 410                 415

Lys Pro Leu Arg Ile Leu Asn Ile Leu Leu Leu Leu Glu Gly Ala Val
            420                 425                 430

Ile Val Tyr Gln Leu Tyr Ser Leu Met Ser Ser Glu Lys Trp His Gln
        435                 440                 445

Thr Ile Ser Leu Ala Leu Ile Leu Phe Ser Asn Tyr Tyr Ala Phe Phe
    450                 455                 460

Lys Leu Leu Arg Asp Arg Leu Val Leu Gly Lys Ala Tyr Ser Tyr Ser
465                 470                 475                 480

Ala Ser Pro Gln Arg Asp Leu Asp His Arg Phe Ser 
                485                 490



<210> 2410
<211> 175
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2410
Met Glu Ala Val Val Asn Leu Tyr Gln Glu Val Met Lys His Ala Asp
  1               5                  10                  15

Pro Arg Ile Gln Gly Tyr Pro Leu Met Gly Ser Pro Leu Leu Met Thr
             20                  25                  30

Ser Ile Leu Leu Thr Tyr Val Tyr Phe Val Leu Ser Leu Gly Pro Arg
         35                  40                  45

Ile Met Ala Asn Arg Lys Pro Phe Gln Leu Arg Gly Phe Met Ile Val
     50                  55                  60

Tyr Asn Phe Ser Leu Val Ala Leu Ser Leu Tyr Ile Val Tyr Glu Phe
 65                  70                  75                  80

Leu Met Ser Gly Trp Leu Ser Thr Tyr Thr Trp Arg Cys Asp Pro Val
                 85                  90                  95

Asp Tyr Ser Asn Ser Pro Glu Ala Leu Arg Met Val Arg Val Ala Trp
            100                 105                 110

Leu Phe Leu Phe Ser Lys Phe Ile Glu Leu Met Asp Thr Val Ile Phe
        115                 120                 125

Ile Leu Arg Lys Lys Asp Gly Gln Val Thr Phe Leu His Val Phe Ile
    130                 135                 140

Thr Leu Cys Phe Leu Glu Leu Val Val Gly Gly Lys Asp Cys Pro Gly
145                 150                 155                 160

Arg Asn Gly Leu Phe Pro Cys Xaa Asp Asn Ser Pro Xaa Met Ser 
                165                 170                 175



<210> 2411
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (130)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2411
Met Ala Gly Pro Leu Trp Arg Thr Ala Ala Phe Val Gln Arg His Arg
  1               5                  10                  15

Thr Gly Leu Leu Val Gly Ser Cys Ala Gly Leu Phe Gly Val Pro Val
             20                  25                  30

Ser Tyr His Leu Phe Pro Asp Pro Val Val Gln Trp Leu Tyr Gln Tyr
         35                  40                  45

Trp Pro Gln Gly Xaa Pro Ala Pro Leu Pro Pro Gln Leu Gln Ser Leu
     50                  55                  60

Phe Gln Glu Val Leu Gln Asp Ile Gly Val Pro Ser Gly His Cys Tyr
 65                  70                  75                  80

Lys Pro Phe Thr Thr Phe Thr Phe Gln Pro Val Ser Ala Gly Phe Pro
                 85                  90                  95

Arg Leu Pro Ala Gly Ala Val Val Gly Ile Pro Ala Ser Phe Leu Gly
            100                 105                 110

Asp Leu Val Ile Asn Thr Asn His Pro Val Val Ile His Gly His Thr
        115                 120                 125

Val Xaa Xaa Arg Ser Gln Gln Ala Pro Gly 
    130                 135



<210> 2412
<211> 326
<212> PRT
<213> Homo sapiens

<400> 2412
Met Thr Phe Phe Gln Val Thr Leu Phe Ala Val Asn Glu Phe Ile Leu
  1               5                  10                  15

Leu Asn Leu Leu Lys Val Lys Asp Ala Gly Gly Ser Met Thr Ile His
             20                  25                  30

Thr Phe Gly Ala Tyr Phe Gly Leu Thr Val Thr Arg Ile Leu Tyr Arg
         35                  40                  45

Arg Asn Leu Glu Gln Ser Lys Glu Arg Gln Asn Ser Val Tyr Gln Ser
     50                  55                  60

Asp Leu Phe Ala Met Ile Gly Thr Leu Phe Leu Trp Met Tyr Trp Pro
 65                  70                  75                  80

Ser Phe Asn Ser Ala Ile Ser Tyr His Gly Asp Ser Gln His Arg Ala
                 85                  90                  95

Ala Ile Asn Thr Tyr Cys Ser Leu Ala Ala Cys Val Leu Thr Ser Val
            100                 105                 110

Ala Ile Ser Ser Ala Leu His Lys Lys Gly Lys Leu Asp Met Val His
        115                 120                 125

Ile Gln Asn Ala Thr Leu Ala Gly Gly Val Ala Val Gly Thr Ala Ala
    130                 135                 140

Glu Met Met Leu Met Pro Tyr Gly Ala Leu Ile Ile Gly Phe Val Cys
145                 150                 155                 160

Gly Ile Ile Ser Thr Leu Gly Phe Val Tyr Leu Thr Pro Phe Leu Glu
                165                 170                 175

Ser Arg Leu His Ile Gln Asp Thr Cys Gly Ile Asn Asn Leu His Gly
            180                 185                 190

Ile Pro Gly Ile Ile Gly Gly Ile Val Gly Ala Val Thr Ala Ala Ser
        195                 200                 205

Ala Ser Leu Glu Val Tyr Gly Lys Glu Gly Leu Val His Ser Phe Asp
    210                 215                 220

Phe Gln Gly Phe Asn Gly Asp Trp Thr Ala Arg Thr Gln Gly Lys Phe
225                 230                 235                 240

Gln Ile Tyr Gly Leu Leu Val Thr Leu Ala Met Ala Leu Met Gly Gly
                245                 250                 255

Ile Ile Val Gly Leu Ile Leu Arg Leu Pro Phe Trp Gly Gln Pro Ser
            260                 265                 270

Asp Glu Asn Cys Phe Glu Asp Ala Val Tyr Trp Glu Met Pro Glu Gly
        275                 280                 285

Asn Ser Thr Val Tyr Ile Pro Glu Asp Pro Thr Phe Lys Pro Ser Gly
    290                 295                 300

Pro Ser Val Pro Ser Val Pro Met Val Ser Pro Leu Pro Met Ala Ser
305                 310                 315                 320

Ser Val Pro Leu Val Pro 
                325



<210> 2413
<211> 126
<212> PRT
<213> Homo sapiens

<400> 2413
Met Leu Ile Leu Arg Gly Val Lys Lys Glu Asp Lys Thr Leu Ala Val
  1               5                  10                  15

Gly Ile Gln Phe Met Phe Leu Arg Ile Leu Ala Trp Met Pro Ser Pro
             20                  25                  30

Val Ile His Gly Ser Ala Ile Asp Thr Thr Cys Val His Trp Ala Leu
         35                  40                  45

Ser Cys Gly Arg Arg Ala Val Cys Arg Tyr Tyr Asn Asn Asp Leu Leu
     50                  55                  60

Arg Asn Arg Phe Ile Gly Leu Gln Phe Phe Phe Lys Thr Gly Ser Val
 65                  70                  75                  80

Ile Cys Phe Ala Leu Val Leu Ala Val Leu Arg Gln Gln Asp Lys Glu
                 85                  90                  95

Ala Arg Thr Lys Glu Ser Arg Ser Ser Pro Ala Val Glu Gln Gln Leu
            100                 105                 110

Leu Val Ser Gly Pro Gly Lys Lys Pro Glu Asp Ser Arg Val 
        115                 120                 125



<210> 2414
<211> 258
<212> PRT
<213> Homo sapiens

<400> 2414
Met Asp Gly Ile Ile Glu Gln Lys Ser Met Leu Val His Ser Lys Ile
  1               5                  10                  15

Ser Asp Ala Gly Lys Arg Asn Gly Leu Ile Asn Thr Arg Asn Leu Met
             20                  25                  30

Ala Glu Ser Arg Asp Gly Leu Val Ser Val Tyr Pro Ala Pro Gln Tyr
         35                  40                  45

Gln Ser His Arg Val Gly Ala Ser Thr Val Pro Ala Ser Leu Asp Ser
     50                  55                  60

Ser Arg Ser Glu Pro Met Gln Gln Leu Leu Asp Pro Asn Thr Leu Gln
 65                  70                  75                  80

Gln Ser Val Glu Ser Arg Tyr Arg Pro Asn Ile Ile Leu Tyr Ser Glu
                 85                  90                  95

Gly Val Leu Arg Ser Trp Gly Asp Gly Val Ala Ala Asp Cys Cys Glu
            100                 105                 110

Thr Thr Phe Ile Glu Asp Arg Ser Pro Thr Lys Asp Ser Leu Glu Tyr
        115                 120                 125

Pro Asp Gly Lys Phe Ile Asp Leu Ser Ala Asp Asp Ile Lys Ile His
    130                 135                 140

Thr Leu Ser Tyr Asp Val Glu Glu Glu Glu Glu Phe Gln Glu Leu Glu
145                 150                 155                 160

Ser Asp Tyr Ser Ser Asp Thr Glu Ser Glu Asp Asn Phe Leu Met Met
                165                 170                 175

Pro Pro Arg Asp His Leu Gly Leu Ser Val Phe Ser Met Leu Cys Cys
            180                 185                 190

Phe Trp Pro Leu Gly Ile Ala Ala Phe Tyr Leu Ser His Glu Thr Asn
        195                 200                 205

Lys Ala Val Ala Lys Gly Asp Leu His Gln Ala Ser Thr Ser Ser Arg
    210                 215                 220

Arg Ala Leu Phe Leu Ala Val Leu Ser Ile Thr Ile Gly Thr Gly Val
225                 230                 235                 240

Tyr Val Gly Val Ala Val Ala Leu Ile Ala Tyr Leu Ser Lys Asn Asn
                245                 250                 255

His Leu 




<210> 2415
<211> 463
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (383)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (384)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2415
Met Ser Gly Pro Glu Ser Ser Pro Pro Ile Gly Gly Pro Cys Glu Ala
  1               5                  10                  15

Ala Pro Ser Ser Ser Leu Pro Thr Pro Pro Gln Gln Pro Phe Ile Ala
             20                  25                  30

Arg Arg His Ile Glu Leu Gly Val Thr Gly Gly Gly Ser Pro Glu Asn
         35                  40                  45

Gly Asp Gly Ala Leu Leu Ala Ile Thr Pro Pro Ala Val Lys Arg Arg
     50                  55                  60

Arg Gly Arg Pro Pro Lys Xaa Asn Arg Ser Pro Ala Asp Ala Gly Arg
 65                  70                  75                  80

Gly Val Asp Xaa Ala Pro Ser Ser Thr Leu Lys Gly Lys Thr Asn Gly
                 85                  90                  95

Ala Xaa Pro Val Pro Gly Pro Glu Thr Leu Ile Val Ala Asp Pro Val
            100                 105                 110

Leu Glu Pro Gln Leu Ile Pro Gly Pro Gln Pro Leu Gly Pro Gln Pro
        115                 120                 125

Val His Arg Pro Asn Pro Leu Leu Ser Pro Val Glu Lys Arg Arg Arg
    130                 135                 140

Gly Arg Pro Pro Lys Ala Arg Asp Leu Pro Ile Pro Gly Thr Ile Ser
145                 150                 155                 160

Ser Ala Gly Asp Gly Asn Ser Glu Ser Arg Thr Gln Pro Pro Pro His
                165                 170                 175

Pro Ser Pro Leu Thr Pro Leu Pro Pro Leu Leu Val Cys Pro Thr Ala
            180                 185                 190

Thr Val Ala Asn Thr Val Thr Thr Val Thr Ile Ser Thr Ser Pro Pro
        195                 200                 205

Lys Arg Lys Arg Gly Arg Pro Pro Lys Asn Pro Pro Ser Pro Arg Pro
    210                 215                 220

Ser Gln Leu Pro Val Leu Asp Arg Asp Ser Thr Ser Val Leu Glu Ser
225                 230                 235                 240

Cys Gly Leu Gly Arg Arg Arg Gln Pro Gln Gly Gln Gly Glu Ser Glu
                245                 250                 255

Gly Ser Ser Ser Asp Glu Asp Gly Ser Arg Pro Leu Thr Arg Leu Ala
            260                 265                 270

Arg Leu Arg Leu Glu Ala Glu Gly Met Arg Gly Arg Lys Ser Gly Gly
        275                 280                 285

Ser Met Val Val Ala Val Ile Gln Asp Asp Leu Asp Leu Ala Asp Ser
    290                 295                 300

Gly Pro Gly Gly Leu Glu Leu Thr Pro Pro Val Val Ser Leu Thr Pro
305                 310                 315                 320

Lys Leu Arg Ser Thr Arg Leu Arg Pro Gly Ser Leu Val Pro Pro Leu
                325                 330                 335

Glu Thr Glu Lys Leu Pro Arg Lys Arg Ala Gly Ala Pro Val Gly Gly
            340                 345                 350

Ser Pro Gly Leu Ala Lys Arg Gly Arg Leu Gln Pro Pro Ser Pro Leu
        355                 360                 365

Gly Pro Glu Gly Ser Val Glu Glu Ser Glu Ala Glu Ala Gln Xaa Xaa
    370                 375                 380

Arg Arg Lys Gly Met Gly Pro His Ala Asp Val Leu Ala Pro Ala Gly
385                 390                 395                 400

Leu Leu Gly Pro Pro Thr Lys Gly Thr Ser Ala Ser Cys Ala Ala Ala
                405                 410                 415

Pro Leu Pro Pro Trp Leu Ala Leu Leu Leu Val Thr Glu Ala Ala Thr
            420                 425                 430

Arg Arg Glu Trp Ala Ala Pro Pro Pro Arg Leu Ser Thr Val Ala Thr
        435                 440                 445

Pro Ser Met Thr Arg Pro Asp Ser Val Asn His Tyr Leu Lys Ser 
    450                 455                 460



<210> 2416
<211> 126
<212> PRT
<213> Homo sapiens

<400> 2416
Met Tyr Ala Gly Ser Cys Ala Leu Ala Ile Asp Ser Val Gly Asn Gly
  1               5                  10                  15

Cys Ala Val Arg Arg Leu Gly Trp Pro His Val Pro Cys Ser Ala Asp
             20                  25                  30

Arg Met Pro Thr Gln Met Lys Arg Ile His Gly Ser Gly His Pro Val
         35                  40                  45

Ser Ser Ala Cys His Gly Trp Glu Phe Val Gly Ile Glu Pro Asn Leu
     50                  55                  60

Val Leu Gln Ser Ser Trp Asp Thr Ser Ser Val Gln His Thr Phe Ser
 65                  70                  75                  80

Tyr Ile Leu Pro Leu Ile Ser Lys Val Pro Lys Ala Leu His Ser Val
                 85                  90                  95

Thr Leu Phe Leu Leu Leu His Ser Gln Ile Ser Tyr Ala Lys Phe Asn
            100                 105                 110

Cys Val Leu Leu Leu Glu Val Phe Arg Val Phe Ile Phe Cys 
        115                 120                 125



<210> 2417
<211> 757
<212> PRT
<213> Homo sapiens

<400> 2417
Met Pro Ala Leu Pro Leu Asp Gln Leu Gln Ile Thr His Lys Asp Pro
  1               5                  10                  15

Lys Thr Gly Lys Leu Arg Thr Ser Pro Ala Leu His Pro Glu Gln Lys
             20                  25                  30

Ala Asp Arg Tyr Phe Val Leu Tyr Lys Pro Pro Pro Lys Asp Asn Ile
         35                  40                  45

Pro Ala Leu Val Glu Glu Tyr Leu Glu Arg Ala Thr Phe Val Ala Asn
     50                  55                  60

Asp Leu Asp Trp Leu Leu Ala Leu Pro His Asp Lys Phe Trp Cys Gln
 65                  70                  75                  80

Val Ile Phe Asp Glu Thr Leu Gln Lys Cys Leu Asp Ser Tyr Leu Arg
                 85                  90                  95

Tyr Val Pro Arg Lys Phe Asp Glu Gly Val Ala Ser Ala Pro Glu Val
            100                 105                 110

Val Asp Met Gln Lys Arg Leu His Arg Ser Val Phe Leu Thr Phe Leu
        115                 120                 125

Arg Met Ser Thr His Lys Glu Ser Lys Asp His Phe Ile Ser Pro Ser
    130                 135                 140

Ala Phe Gly Glu Ile Leu Tyr Asn Asn Phe Leu Phe Asp Ile Pro Lys
145                 150                 155                 160

Ile Leu Asp Leu Cys Val Leu Phe Gly Lys Gly Asn Ser Pro Leu Leu
                165                 170                 175

Gln Lys Met Ile Gly Asn Ile Phe Thr Gln Gln Pro Ser Tyr Tyr Ser
            180                 185                 190

Asp Leu Asp Glu Thr Leu Pro Thr Ile Leu Gln Val Phe Ser Asn Ile
        195                 200                 205

Leu Gln His Cys Gly Leu Gln Gly Asp Gly Ala Asn Thr Thr Pro Gln
    210                 215                 220

Lys Leu Glu Glu Arg Gly Arg Leu Thr Pro Ser Asp Met Pro Leu Leu
225                 230                 235                 240

Glu Leu Lys Asp Ile Val Leu Tyr Leu Cys Asp Thr Cys Thr Thr Leu
                245                 250                 255

Trp Ala Phe Leu Asp Ile Phe Pro Leu Ala Cys Gln Thr Phe Gln Lys
            260                 265                 270

His Asp Phe Cys Tyr Arg Leu Ala Ser Phe Tyr Glu Ala Ala Ile Pro
        275                 280                 285

Glu Met Glu Ser Ala Ile Lys Lys Arg Arg Leu Glu Asp Ser Lys Leu
    290                 295                 300

Leu Gly Asp Leu Trp Gln Arg Leu Ser His Ser Arg Lys Lys Leu Met
305                 310                 315                 320

Glu Ile Phe His Ile Ile Leu Asn Gln Ile Cys Leu Leu Pro Ile Leu
                325                 330                 335

Glu Ser Ser Cys Asp Asn Ile Gln Gly Phe Ile Glu Glu Phe Leu Gln
            340                 345                 350

Ile Phe Ser Ser Leu Leu Gln Glu Lys Arg Phe Leu Arg Asp Tyr Asp
        355                 360                 365

Ala Leu Phe Pro Val Ala Glu Asp Ile Ser Leu Leu Gln Gln Ala Ser
    370                 375                 380

Ser Val Leu Asp Glu Thr Arg Thr Ala Tyr Ile Leu Gln Ala Val Glu
385                 390                 395                 400

Ser Ala Trp Glu Gly Val Asp Arg Arg Lys Ala Thr Asp Ala Lys Asp
                405                 410                 415

Pro Ser Val Ile Glu Glu Pro Asn Gly Glu Pro Asn Gly Val Thr Val
            420                 425                 430

Thr Ala Glu Ala Val Ser Gln Ala Ser Ser His Pro Glu Asn Ser Glu
        435                 440                 445

Glu Glu Glu Cys Met Gly Ala Ala Ala Ala Val Gly Pro Ala Met Cys
    450                 455                 460

Gly Val Glu Leu Asp Ser Leu Ile Ser Gln Val Lys Asp Leu Leu Pro
465                 470                 475                 480

Asp Leu Gly Glu Gly Phe Ile Leu Ala Cys Leu Glu Tyr Tyr His Tyr
                485                 490                 495

Asp Pro Glu Gln Val Ile Asn Asn Ile Leu Glu Glu Arg Leu Ala Pro
            500                 505                 510

Thr Leu Ser Gln Leu Asp Arg Asn Leu Asp Arg Glu Met Lys Pro Asp
        515                 520                 525

Pro Thr Pro Leu Leu Thr Ser Arg His Asn Val Phe Gln Asn Asp Glu
    530                 535                 540

Phe Asp Val Phe Ser Arg Asp Ser Val Asp Leu Ser Arg Val His Lys
545                 550                 555                 560

Gly Lys Ser Thr Arg Lys Glu Glu Asn Thr Arg Ser Leu Leu Asn Asp
                565                 570                 575

Lys Arg Ala Val Ala Ala Gln Arg Gln Arg Tyr Glu Gln Tyr Ser Val
            580                 585                 590

Val Val Glu Glu Val Pro Leu Gln Pro Gly Glu Ser Leu Pro Tyr His
        595                 600                 605

Ser Val Tyr Tyr Glu Asp Glu Tyr Asp Asp Thr Tyr Asp Gly Asn Gln
    610                 615                 620

Val Gly Ala Asn Asp Ala Asp Ser Asp Asp Glu Leu Ile Ser Arg Arg
625                 630                 635                 640

Pro Phe Thr Ile Pro Gln Val Leu Arg Thr Lys Val Pro Arg Glu Gly
                645                 650                 655

Gln Glu Glu Asp Asp Asp Asp Glu Glu Asp Asp Ala Asp Glu Glu Ala
            660                 665                 670

Pro Lys Pro Asp His Phe Val Gln Asp Pro Ala Val Leu Arg Glu Lys
        675                 680                 685

Ala Glu Ala Arg Arg Met Ala Phe Leu Ala Lys Lys Gly Tyr Arg His
    690                 695                 700

Asp Ser Ser Thr Ala Val Ala Gly Ser Pro Arg Gly His Gly Gln Ser
705                 710                 715                 720

Arg Glu Thr Thr Gln Glu Arg Arg Lys Lys Glu Ala Asn Lys Ala Thr
                725                 730                 735

Arg Ala Asn His Asn Arg Arg Thr Met Ala Asp Arg Lys Arg Ser Lys
            740                 745                 750

Gly Met Ile Pro Ser 
        755



<210> 2418
<211> 152
<212> PRT
<213> Homo sapiens

<400> 2418
Met Arg Ser Leu Leu His Leu Leu Gly Leu Lys Leu Phe Arg Gly Ala
  1               5                  10                  15

Gly Thr Val Tyr Pro Arg Asp Thr Pro Ile Ser Leu Leu Pro Lys Trp
             20                  25                  30

Ile Leu Arg Gln Ala Pro Ser Pro Cys Ser Pro Ser Leu Phe Cys Leu
         35                  40                  45

Pro Leu Thr Ala Leu Phe His Val Ser Ser Phe Cys Leu Lys Lys Ala
     50                  55                  60

Phe Pro Gly Cys Thr Ser Ser Glu Gly Ala Ala Tyr Leu Pro Gln Ala
 65                  70                  75                  80

Gly Gly Gly Arg Gly Leu Gly Gln Ala Pro Thr Cys Leu Pro Ala Arg
                 85                  90                  95

Leu Leu Gln Ala Ser Gly Leu Ala Glu Pro Pro Glu Pro Arg Pro Val
            100                 105                 110

Ser Ser Pro Ser Gly Ser Leu Asn Phe Gln Gly Ser Gln Gly Val Leu
        115                 120                 125

Leu Arg Ser Gln Ser Pro Ala Leu Cys Leu Gln Pro Trp Lys Gly Val
    130                 135                 140

Cys Thr Cys Leu Cys Val Cys Gly 
145                 150



<210> 2419
<211> 121
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (25)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2419
Met Glu Leu Leu Ser Ala Leu Ser Leu Gly Glu Leu Ala Leu Ser Xaa
  1               5                  10                  15

Ser Arg Val Pro Leu Phe Pro Val Xaa Asp Leu Ser Tyr Phe Ile Val
             20                  25                  30

Ser Ile Leu Tyr Leu Lys Tyr Glu Pro Gly Ala Val Glu Leu Ser Arg
         35                  40                  45

Arg His Pro Ile Ala Ser Trp Leu Cys Ala Met Leu His Cys Phe Gly
     50                  55                  60

Ser Tyr Ile Leu Ala Asp Leu Leu Leu Gly Glu Pro Leu Ile Asp Tyr
 65                  70                  75                  80

Phe Ser Asn Asn Ser Ser Ile Leu Leu Ala Ser Ala Val Trp Tyr Leu
                 85                  90                  95

Ile Phe Phe Cys Pro Leu Asp Leu Phe Tyr Lys Cys Val Cys Phe Pro
            100                 105                 110

Ala Cys Glu Thr His Leu Pro Trp Pro 
        115                 120



<210> 2420
<211> 142
<212> PRT
<213> Homo sapiens

<400> 2420
Met Ala Ala Val Val Ala Ala Thr Ala Leu Lys Gly Arg Gly Ala Arg
  1               5                  10                  15

Asn Ala Arg Val Leu Arg Gly Ile Leu Ala Gly Ala Thr Ala Asn Lys
             20                  25                  30

Ala Ser His Asn Arg Thr Arg Ala Leu Gln Ser His Ser Ser Pro Glu
         35                  40                  45

Gly Lys Glu Glu Pro Glu Pro Leu Ser Pro Glu Leu Glu Tyr Ile Pro
     50                  55                  60

Arg Lys Arg Gly Lys Asn Pro Met Lys Ala Val Gly Leu Ala Trp Ala
 65                  70                  75                  80

Ile Gly Phe Pro Cys Gly Ile Leu Leu Phe Ile Leu Thr Lys Arg Glu
                 85                  90                  95

Val Asp Lys Asp Arg Val Lys Gln Met Lys Ala Arg Gln Asn Met Arg
            100                 105                 110

Leu Ser Asn Thr Gly Glu Tyr Glu Ser Gln Arg Phe Arg Ala Ser Ser
        115                 120                 125

Gln Ser Ala Pro Ser Pro Asp Val Gly Ser Gly Val Gln Thr 
    130                 135                 140



<210> 2421
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (37)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2421
Met Ile Phe Trp Trp His Arg Cys Cys Leu Ser His Ser Trp Tyr Asn
  1               5                  10                  15

Cys Arg Val Cys Ala Asp Ser Trp Pro Pro Ala Ser Pro Ile Leu Ser
             20                  25                  30

Gly Pro Ser Leu Xaa Cys Ser Pro Val Leu Gln Gly Pro Arg Cys Phe
         35                  40                  45

Pro Leu Pro Pro Arg Cys Arg Leu Trp Leu Ala Val Ala Ala Ala Leu
     50                  55                  60

Gly Ser Xaa Phe Ser Ala Val Xaa Trp Gly Ser Leu Cys Ala Xaa Cys
 65                  70                  75                  80

Val Leu Gly Asn Thr Val Val Val Lys Gly Ser Ser Phe Phe Xaa Val
                 85                  90                  95

Gln Pro Leu Xaa Ser His Asn Pro Ser 
            100                 105



<210> 2422
<211> 101
<212> PRT
<213> Homo sapiens

<400> 2422
Met Ser Cys Ala Ser Gln Ile Pro Arg Phe Trp Glu Glu Arg Leu Pro
  1               5                  10                  15

His Ser Ala Ala Pro His Ser Glu Gln Ser Cys Thr His Leu His Ser
             20                  25                  30

Val Phe Ser Trp His Tyr Lys Glu Trp Glu Gly Leu Gly Phe Ala Ala
         35                  40                  45

Ala Pro Leu Glu Gln Gly Pro Ser Phe Gln His Phe Gly His Leu Glu
     50                  55                  60

Thr Gln Pro Cys Tyr Leu Met Val Val Gly Lys Cys Val Cys Ile Leu
 65                  70                  75                  80

Ser Ala Thr Ala Phe Ser Leu Pro His Ala Arg Glu Pro Cys Pro Cys
                 85                  90                  95

Gln Ala Gln Pro Ser 
            100



<210> 2423
<211> 197
<212> PRT
<213> Homo sapiens

<400> 2423
Met Asn Ile His Phe Arg Gly Lys Thr Lys Ser Phe Pro Glu Glu Lys
  1               5                  10                  15

Asp Gly Ala Ser Ser Cys Leu Gly Lys Ser Leu Gly Ser Glu Asp Ser
             20                  25                  30

Arg Asn Met Lys Glu Lys Leu Glu Asp Met Glu Ser Val Leu Lys Asp
         35                  40                  45

Leu Thr Glu Glu Lys Arg Lys Asp Val Leu Asn Ser Leu Ala Lys Cys
     50                  55                  60

Leu Gly Lys Glu Asp Ile Arg Gln Asp Leu Glu Gln Arg Val Ser Glu
 65                  70                  75                  80

Val Leu Ile Ser Gly Glu Leu His Met Glu Asp Pro Asp Lys Pro Leu
                 85                  90                  95

Leu Ser Ser Leu Phe Asn Ala Ala Gly Val Leu Val Glu Ala Arg Ala
            100                 105                 110

Lys Ala Ile Leu Asp Phe Leu Asp Ala Leu Leu Glu Leu Ser Glu Glu
        115                 120                 125

Gln Gln Phe Val Ala Glu Ala Leu Glu Lys Gly Thr Leu Pro Leu Leu
    130                 135                 140

Lys Asp Gln Val Lys Ser Val Met Glu Gln Asn Trp Asp Glu Leu Ala
145                 150                 155                 160

Ser Ser Pro Pro Asp Met Asp Tyr Asp Pro Glu Ala Arg Ile Leu Cys
                165                 170                 175

Ala Leu Tyr Val Val Val Ser Ile Leu Leu Glu Leu Ala Glu Gly Pro
            180                 185                 190

Thr Ser Val Ser Ser 
        195



<210> 2424
<211> 170
<212> PRT
<213> Homo sapiens

<400> 2424
Met Lys Leu Leu Lys Leu Arg Arg Asn Ile Val Lys Leu Ser Leu Tyr
  1               5                  10                  15

Arg His Phe Thr Asn Thr Leu Ile Leu Ala Val Ala Ala Ser Ile Val
             20                  25                  30

Phe Ile Ile Trp Thr Thr Met Lys Phe Arg Ile Val Thr Cys Gln Ser
         35                  40                  45

Asp Trp Arg Glu Leu Trp Val Asp Asp Ala Ile Trp Arg Leu Leu Phe
     50                  55                  60

Ser Met Ile Leu Phe Val Ile Met Val Leu Trp Arg Pro Ser Ala Asn
 65                  70                  75                  80

Asn Gln Arg Phe Ala Phe Ser Pro Leu Ser Glu Glu Glu Glu Glu Asp
                 85                  90                  95

Glu Gln Lys Glu Pro Met Leu Lys Glu Ser Phe Glu Gly Met Lys Met
            100                 105                 110

Arg Ser Thr Lys Gln Glu Pro Asn Gly Asn Ser Lys Val Asn Lys Ala
        115                 120                 125

Gln Glu Asp Asp Leu Lys Trp Val Glu Glu Asn Val Pro Ser Ser Val
    130                 135                 140

Thr Asp Val Ala Leu Pro Ala Leu Leu Asp Ser Asp Glu Glu Arg Met
145                 150                 155                 160

Ile Thr His Phe Glu Arg Ser Lys Met Glu 
                165                 170



<210> 2425
<211> 155
<212> PRT
<213> Homo sapiens

<400> 2425
Met Thr Val Glu Lys Ala Ser Pro Val Gly Asp Gly Asn Phe Arg Asn
  1               5                  10                  15

Arg Ser Ala Pro Pro Cys Ala Asn Ser Thr Val Gly Val Val Lys Met
             20                  25                  30

Thr Pro Leu Ser Phe Ile Pro Gly Ala Lys Ile Thr Lys Tyr Leu Gly
         35                  40                  45

Ile Ile Asn Met Phe Phe Ile Arg Glu Thr Thr Ser Leu Arg Glu Glu
     50                  55                  60

Gly Gly Val Ser Gly Phe Leu His Ala Phe Ile Ala Glu Val Phe Ala
 65                  70                  75                  80

Met Val Arg Ala His Val Ala Ala Leu Gly Gly Asn Ala Val Val Ser
                 85                  90                  95

Tyr Ile Met Lys Gln Cys Val Phe Met Glu Asn Pro Asn Lys Asn Gln
            100                 105                 110

Ala Gln Cys Leu Ile Asn Val Ser Gly Asp Ala Val Val Phe Val Arg
        115                 120                 125

Glu Ser Asp Leu Glu Val Val Ser Ser Gln Gln Pro Thr Thr Asn Cys
    130                 135                 140

Gln Ser Ser Cys Thr Glu Gly Glu Val Thr Thr 
145                 150                 155



<210> 2426
<211> 163
<212> PRT
<213> Homo sapiens

<400> 2426
Met Asp Ser Pro Glu Val Thr Phe Thr Leu Ala Tyr Leu Val Phe Ala
  1               5                  10                  15

Val Cys Phe Val Phe Thr Pro Asn Glu Phe His Ala Ala Gly Leu Thr
             20                  25                  30

Val Gln Asn Leu Leu Ser Gly Trp Leu Gly Ser Glu Asp Ala Ala Phe
         35                  40                  45

Val Pro Phe His Leu Arg Arg Thr Ala Ala Thr Leu Leu Cys His Ser
     50                  55                  60

Leu Leu Pro Leu Gly Tyr Tyr Val Gly Met Cys Leu Ala Ala Ser Glu
 65                  70                  75                  80

Lys Arg Leu His Ala Leu Ser Gln Ala Pro Glu Ala Trp Arg Leu Phe
                 85                  90                  95

Leu Leu Leu Ala Val Thr Leu Pro Ser Ile Ala Cys Ile Leu Ile Tyr
            100                 105                 110

Tyr Trp Ser Arg Asp Arg Trp Ala Cys His Pro Leu Ala Arg Thr Leu
        115                 120                 125

Ala Leu Tyr Ala Leu Pro Gln Ser Gly Trp Gln Ala Val Ala Ser Ser
    130                 135                 140

Val Asn Thr Glu Phe Arg Arg Ile Asp Asn Leu Pro Pro Val His Gln
145                 150                 155                 160

Val Pro Val 




<210> 2427
<211> 127
<212> PRT
<213> Homo sapiens

<400> 2427
Met Val Gln Ile Ala Ala Ala Ala Val His Gln Pro Arg Asp Gln Gly
  1               5                  10                  15

Ile Ser Arg Arg Pro Gly Ala Gly His Gly Ala Ala Gln Arg Thr Gly
             20                  25                  30

Ala Ile Val Gln Ile Asp Arg Leu Val Ala Val Leu Phe Asp Gln Ala
         35                  40                  45

Leu His Ile Gly Arg Asp Asp Val Val Gly Phe Phe Pro Ala Asn Ala
     50                  55                  60

Leu Glu Phe Ala Phe Thr Ala Arg Pro Asp Ser Phe His Arg Ile Phe
 65                  70                  75                  80

Gln Ala Val Arg Ile Val Asp Thr Ala Thr His Gly Thr Pro Thr Gln
                 85                  90                  95

Ala Gly Ala Asn Leu Val Gln Ala Val Val Ile Val Ile Ala Gly Ile
            100                 105                 110

Val Arg Phe Asp Ile Phe Asp Phe Thr Val His Asp Val His Thr 
        115                 120                 125



<210> 2428
<211> 196
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2428
Met Gly Cys Arg Ala Asn Ala Ser Xaa Ile Xaa Arg Xaa Ala Trp Tyr
  1               5                  10                  15

Gln Lys Xaa Tyr Pro Gly Pro Gly Thr Gln Ala His Ser Arg Met Ala
             20                  25                  30

Ser Gly Leu Thr Leu Arg Arg Leu Arg Arg Ala Glu Asp Glu Asp Ala
         35                  40                  45

Ala Pro Gly Trp Ser Gln Thr Leu Arg Thr Cys Pro Ala Gln Gly Leu
     50                  55                  60

Arg Ala Thr Gly Leu Ala Ser Tyr Gly Met Arg Gly Ser Trp His Arg
 65                  70                  75                  80

Ser Pro Leu Pro Ala Val Val Leu Pro Ser Val Leu Gln Thr Ala Leu
                 85                  90                  95

Ser Pro Leu Ala Leu Cys Gln Ala Trp Arg Arg Ala Val Pro His Gly
            100                 105                 110

Val Pro Ser Gln Arg Leu Arg Asn Gln Glu Ala Ser Leu Val Pro Lys
        115                 120                 125

Gly Val Pro Arg Ala Trp Tyr Pro Gly Pro Leu Gln Asn Gly Leu Trp
    130                 135                 140

Thr His Leu Glu Lys Gly Glu Leu Leu Gly Leu Lys Pro Thr Pro Gly
145                 150                 155                 160

Gly Leu Leu Leu Leu Arg Ser Phe Trp Asp Pro His Pro Ser Arg Pro
                165                 170                 175

Phe Leu Cys Thr Leu Leu Pro Pro Pro Leu Xaa Ile Phe Pro Pro Leu
            180                 185                 190

Arg Cys Ser Ala 
        195



<210> 2429
<211> 342
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (183)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2429
Met Arg Ser Ser Cys Val Leu Leu Thr Ala Leu Val Ala Leu Ala Ala
  1               5                  10                  15

Tyr Tyr Val Tyr Ile Pro Leu Pro Gly Ser Val Ser Asp Pro Trp Lys
             20                  25                  30

Leu Met Leu Leu Asp Ala Thr Phe Arg Gly Ala Gln Gln Val Ser Asn
         35                  40                  45

Leu Ile His Tyr Leu Gly Leu Ser His His Leu Leu Ala Leu Asn Phe
     50                  55                  60

Ile Ile Val Ser Phe Gly Lys Lys Ser Ala Trp Ser Ser Ala Gln Val
 65                  70                  75                  80

Lys Val Thr Asp Thr Asp Phe Asp Gly Val Glu Val Arg Val Phe Glu
                 85                  90                  95

Gly Pro Pro Lys Pro Glu Glu Pro Leu Lys Arg Ser Val Val Tyr Ile
            100                 105                 110

His Gly Gly Gly Trp Ala Leu Ala Ser Ala Lys Ile Arg Xaa Tyr Asp
        115                 120                 125

Glu Leu Cys Thr Ala Met Ala Glu Glu Leu Asn Ala Val Ile Val Ser
    130                 135                 140

Ile Glu Tyr Arg Leu Val Pro Xaa Val Tyr Phe Pro Glu Gln Ile His
145                 150                 155                 160

Asp Val Val Arg Ala Thr Lys Tyr Phe Leu Lys Pro Glu Val Leu Gln
                165                 170                 175

Lys Tyr Met Val Asp Pro Xaa Arg Ile Cys Ile Ser Gly Asp Ser Ala
            180                 185                 190

Gly Gly Asn Leu Ala Ala Ala Leu Gly Gln Gln Phe Thr Gln Asp Ala
        195                 200                 205

Xaa Leu Lys Asn Lys Leu Lys Leu Gln Ala Leu Ile Tyr Pro Val Leu
    210                 215                 220

Gln Ala Leu Asp Phe Asn Thr Pro Ser Tyr Gln Gln Asn Val Asn Thr
225                 230                 235                 240

Pro Ile Leu Pro Arg Tyr Val Met Val Lys Tyr Trp Val Asp Tyr Phe
                245                 250                 255

Lys Gly Asn Tyr Asp Phe Val Gln Ala Met Ile Val Asn Asn His Thr
            260                 265                 270

Ser Leu Asp Val Glu Glu Ala Ala Ala Val Arg Ala Arg Leu Asn Trp
        275                 280                 285

Thr Ser Leu Leu Pro Ala Ser Phe Thr Lys Asn Tyr Lys Pro Val Val
    290                 295                 300

Gln Thr Thr Gly Asn Ala Gly Leu Ser Arg Ser Phe Leu Ser Cys Trp
305                 310                 315                 320

Met Pro Ala Pro Pro His Ser Leu Gln Thr Arg Gln Cys Cys Ser Ser
                325                 330                 335

Ser Gln Arg Pro Thr Phe 
            340



<210> 2430
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2430
Met Cys Leu Arg Ala Ile Met Asn Tyr Gln Ser Gly Phe Ser Leu Val
  1               5                  10                  15

Met Asn His Pro Ala Cys Val Asn Glu Ile Ala Leu Ser Leu Asn Asn
             20                  25                  30

Lys Asn Pro Arg Thr Lys Ala Leu Val Leu Glu Leu Leu Ala Ala Val
         35                  40                  45

Cys Leu Val Arg Gly Gly His Asp Ile Ile Leu Ala Ala Phe Asp Asn
     50                  55                  60

Phe Lys Glu Val Cys Gly Glu Gln His Arg Phe Glu Lys Leu Met Glu
 65                  70                  75                  80

Tyr Phe Arg Asn Glu Asp Ser Asn Ile Asp Phe Met Val Ala Cys Met
                 85                  90                  95

Gln Phe Ile Asn Ile Val Val His Ser Val Xaa Asn Met Asn Phe Arg
            100                 105                 110

Val Phe Cys Ile Met Xaa Ser Pro Xaa Trp Ala Trp Thr Cys Thr Trp
        115                 120                 125






<210> 2431
<211> 154
<212> PRT
<213> Homo sapiens

<400> 2431
Met Gly Ser Leu Ser Gly Leu Arg Leu Ala Ala Gly Ser Cys Phe Arg
  1               5                  10                  15

Leu Cys Glu Arg Asp Val Ser Ser Ser Leu Arg Leu Thr Arg Ser Ser
             20                  25                  30

Asp Leu Lys Arg Ile Asn Gly Phe Cys Thr Lys Pro Gln Glu Ser Pro
         35                  40                  45

Gly Ala Pro Ser Arg Thr Tyr Asn Arg Val Pro Leu His Lys Pro Thr
     50                  55                  60

Asp Trp Gln Lys Lys Ile Leu Ile Trp Ser Gly Arg Phe Lys Lys Glu
 65                  70                  75                  80

Asp Glu Ile Pro Glu Thr Val Ser Leu Glu Met Leu Asp Ala Ala Lys
                 85                  90                  95

Asn Lys Met Arg Val Lys Ile Ser Tyr Leu Met Ile Ala Leu Thr Val
            100                 105                 110

Val Gly Cys Ile Phe Met Val Ile Glu Gly Lys Lys Ala Ala Gln Arg
        115                 120                 125

His Glu Thr Leu Thr Ser Leu Asn Leu Glu Lys Lys Ala Arg Leu Lys
    130                 135                 140

Glu Glu Ala Ala Met Lys Ala Lys Thr Glu 
145                 150



<210> 2432
<211> 189
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (138)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (180)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2432
Met Asp Pro Glu Cys Ala Gln Leu Leu Pro Ala Leu Cys Ala Val Leu
  1               5                  10                  15

Val Asp Pro Arg Gln Pro Val Ala Asp Asp Thr Cys Leu Glu Lys Leu
             20                  25                  30

Leu Asp Trp Phe Lys Thr Val Thr Glu Gly Glu Ser Ser Val Val Leu
         35                  40                  45

Leu Gln Glu His Pro Cys Leu Val Glu Leu Leu Ser His Val Leu Lys
     50                  55                  60

Val Gln Asp Leu Ser Ser Gly Val Leu Ser Phe Ser Leu Arg Leu Ala
 65                  70                  75                  80

Gly Thr Phe Ala Ala Gln Glu Asn Cys Phe Gln Tyr Leu Gln Gln Gly
                 85                  90                  95

Glu Leu Leu Pro Gly Leu Phe Gly Glu Pro Gly Pro Leu Gly Arg Ala
            100                 105                 110

Thr Trp Ala Val Pro Thr Val Arg Ser Gly Trp Ile Gln Gly Leu Arg
        115                 120                 125

Ser Leu Ala Gln His Pro Ser Ala Leu Xaa Phe Leu Ala Asp His Gly
    130                 135                 140

Ala Val Asp Thr Ile Phe Ser Leu Gln Gly Asp Ser Ser Leu Phe Val
145                 150                 155                 160

Ala Ser Ala Ala Ser Gln Leu Leu Val His Val Leu Ala Leu Ser Met
                165                 170                 175

Arg Xaa Gly Xaa Glu Gly Gln Pro Cys Leu Pro Gly Gly 
            180                 185



<210> 2433
<211> 238
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (228)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2433
Met Ala Ala Asp Gly Gln Cys Ser Leu Pro Ala Ser Trp Arg Pro Val
  1               5                  10                  15

Thr Leu Thr His Val Glu Tyr Pro Ala Gly Asp Leu Ser Gly His Leu
             20                  25                  30

Leu Ala Tyr Leu Ser Leu Ser Pro Val Phe Val Ile Val Gly Phe Val
         35                  40                  45

Thr Leu Ile Ile Phe Lys Arg Glu Leu His Thr Ile Ser Phe Leu Gly
     50                  55                  60

Gly Leu Ala Leu Asn Glu Gly Val Asn Trp Leu Ile Lys Asn Val Ile
 65                  70                  75                  80

Gln Glu Pro Arg Pro Cys Gly Gly Pro His Thr Ala Val Gly Thr Lys
                 85                  90                  95

Tyr Gly Met Pro Ser Ser His Ser Gln Phe Met Trp Phe Phe Ser Val
            100                 105                 110

Tyr Ser Phe Leu Phe Leu Tyr Leu Arg Met His Gln Thr Asn Asn Ala
        115                 120                 125

Arg Phe Leu Asp Leu Leu Trp Arg His Val Leu Ser Leu Gly Leu Leu
    130                 135                 140

Ala Xaa Ala Phe Leu Val Xaa Tyr Ser Arg Val Tyr Leu Leu Tyr His
145                 150                 155                 160

Thr Trp Ser Gln Val Leu Tyr Gly Gly Ile Ala Gly Gly Leu Met Ala
                165                 170                 175

Ile Ala Trp Phe Ile Phe Thr Gln Glu Val Leu Thr Pro Leu Phe Pro
            180                 185                 190

Arg Ile Ala Ala Trp Pro Val Ser Glu Phe Phe Leu Ile Arg Asp Thr
        195                 200                 205

Ser Leu Ile Pro Asn Val Leu Trp Phe Glu Tyr Thr Val Thr Arg Ala
    210                 215                 220

Glu Ala Arg Xaa Arg Gln Arg Lys Leu Gly Thr Lys Leu Gln 
225                 230                 235



<210> 2434
<211> 110
<212> PRT
<213> Homo sapiens

<400> 2434
Met Val Asp Leu Trp His Pro Asn Val Ala Ala Ala Glu Arg Arg Leu
  1               5                  10                  15

Leu Ile Ser Ser Leu Leu Arg Asp Asp Glu Ser Ile Ser His Ala Gly
             20                  25                  30

Val Gly Glu Lys Gly Arg Gly Gly Ala Trp Ala Asp Cys Gly Pro Val
         35                  40                  45

Gln Ser Leu Pro Val Leu Phe Pro Cys Ser Glu Thr Cys Leu Ser Gly
     50                  55                  60

Lys Leu Leu Phe Gly Ile Leu Tyr His Val Gly Ser Leu Phe Pro Leu
 65                  70                  75                  80

Val Ile Val Asn Gly Asn Phe Ser Ala Cys Ile Ser Leu Asp Phe Phe
                 85                  90                  95

Phe Phe Leu Pro Ile Ile Cys Phe Arg Asp Ser Phe Leu Ala 
            100                 105                 110



<210> 2435
<211> 233
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (175)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2435
Met Ala Glu Ala Ala Ser Pro His Leu Ser Leu Pro Ser Gly Leu Leu
  1               5                  10                  15

Glu Leu Cys Ala Leu Leu Gly Ala Pro Arg Asp Ser Leu Arg Ser Leu
             20                  25                  30

Glu Gln Val Ala Tyr Lys Lys Gly Val Lys His Leu Ser Ala Leu Leu
         35                  40                  45

Asp Pro Glu Val Leu Ser Ile Phe Val Pro Pro Phe Ile Ser Lys Glu
     50                  55                  60

Asp Ser Gln Thr Ala Gly Ala Asn Cys Gly Thr Leu Gly Lys Thr Arg
 65                  70                  75                  80

Met Arg Ser Leu Arg Lys Lys Arg Glu Lys Pro Arg Pro Glu Gln Trp
                 85                  90                  95

Lys Gly Leu Pro Gly Pro Pro Xaa Ala Pro Xaa Pro Glu Asp Val Ala
            100                 105                 110

Val Pro Gly Gly Val Asp Leu Leu Thr Leu Pro Gln Leu Cys Phe Pro
        115                 120                 125

Gly Gly Val Cys Val Ala Thr Glu Pro Lys Glu Asp Cys Val His Phe
    130                 135                 140

Leu Val Leu Thr Asp Val Cys Gly Asn Arg Thr Tyr Gly Val Val Ala
145                 150                 155                 160

Gln Tyr Tyr Arg Pro Leu His Asp Glu Tyr Cys Phe Tyr Asn Xaa Lys
                165                 170                 175

Thr His Arg Glu Cys Pro Gly Cys Phe Val Pro Phe Ala Val Cys Val
            180                 185                 190

Val Ser Xaa Phe Pro Tyr Tyr Asn Ser Leu Lys Asp Cys Leu Ser Cys
        195                 200                 205

Leu Leu Ala Leu Leu Lys Pro Cys Lys Asp Phe Glu Val Asp Ser His
    210                 215                 220

Ile Lys Asp Phe Ala Ala Xaa Cys Leu 
225                 230



<210> 2436
<211> 137
<212> PRT
<213> Homo sapiens

<400> 2436
Met Lys Ser Pro Thr Cys Trp Ile Cys Thr Cys Ser Trp Ala Ala Pro
  1               5                  10                  15

Ser Pro Arg Pro Thr Pro Gln Gly Ala Leu Arg Cys Gly Arg Cys Gly
             20                  25                  30

Trp His Ala Gly Ser Gly Ala Thr Glu Cys Gly Gly His Gln Gln Thr
         35                  40                  45

Phe Pro Cys Thr Thr Val Cys Leu Ala Leu Cys Trp Ala Leu Gly Ala
     50                  55                  60

Leu Pro Ala Gly Ala Ile Ile Cys Glu Lys Glu His Cys Met Ala Thr
 65                  70                  75                  80

Glu Gly Gln Gln Leu Arg Gln Pro Lys Thr Glu Thr Phe Glu Gln Gly
                 85                  90                  95

Leu Glu Gly Cys Ala Gly Val Arg Gln Gln Ser Gln Ala Gly Gln Asp
            100                 105                 110

Leu Ser Trp Gln Leu Ser Cys Cys Cys Phe His Val Phe Trp Val Gln
        115                 120                 125

Arg Ser Trp Leu His Arg Ser Glu Pro 
    130                 135



<210> 2437
<211> 138
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2437
Met Pro Arg Pro Glu Val Thr Arg Pro Gly Pro Ser Ser Leu Pro Ser
  1               5                  10                  15

Thr Ile Pro Leu Arg Leu Arg Ala Pro Gly His Pro Ala Ser Pro Ser
             20                  25                  30

Asp Gly Arg Glu Asp Gly Cys Thr Glu Leu Ala Gly Arg Ala Gly Pro
         35                  40                  45

Ala Gly Xaa Gly Gly Leu Gly Xaa Xaa Arg Glu Met Leu Ser Val Gly
     50                  55                  60

Leu Gly Phe Leu Arg Thr Glu Leu Gly Leu Asp Leu Gly Leu Glu Pro
 65                  70                  75                  80

Lys Arg Tyr Pro Gly Trp Val Ile Leu Val Gly Thr Gly Ala Leu Gly
                 85                  90                  95

Leu Leu Leu Leu Phe Leu Leu Gly Tyr Gly Trp Ala Arg Leu Ala Arg
            100                 105                 110

Arg Pro Gln Lys Ala Arg Ser Pro Pro Arg Lys Arg Glu Glu Ala Ala
        115                 120                 125

Ala Val Pro Ala Ala Val Pro Xaa Asp Leu 
    130                 135



<210> 2438
<211> 143
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2438
Met Thr Gln Leu Arg Gln Val Leu Glu Ser Arg Leu Gln Arg Pro Leu
  1               5                  10                  15

Pro Glu Asp Leu Ala Glu Ala Leu Ala Ser Gly Val Ile Leu Cys Gln
             20                  25                  30

Leu Ala Asn Gln Leu Arg Xaa Arg Ser Val Pro Phe Ile His Val Pro
         35                  40                  45

Ser Pro Ala Val Pro Lys Leu Ser Ala Leu Lys Ala Arg Lys Asn Val
     50                  55                  60

Glu Ser Phe Leu Glu Ala Cys Arg Lys Met Gly Val Pro Glu Ala Asp
 65                  70                  75                  80

Leu Cys Ser Pro Ser Asp Leu Leu Gln Gly Thr Ala Arg Gly Leu Arg
                 85                  90                  95

Thr Ala Leu Glu Ala Val Lys Arg Val Gly Gly Lys Ala Leu Pro Pro
            100                 105                 110

Leu Trp Pro Pro Ser Gly Leu Gly Gly Phe Val Val Phe Tyr Val Val
        115                 120                 125

Leu Met Leu Leu Leu Tyr Val Thr Tyr Thr Arg Leu Leu Gly Ser 
    130                 135                 140



<210> 2439
<211> 114
<212> PRT
<213> Homo sapiens

<400> 2439
Met Glu Thr Lys Val Gly Ile Cys Leu Arg Ser Asn Leu Leu His Pro
  1               5                  10                  15

Phe Ser Pro Ser Ser Leu Ser Ala Leu Phe Lys Ala Arg Ile Leu Ser
             20                  25                  30

Met Arg Thr Pro Leu Trp Thr Thr Glu Arg Phe Ser Leu Ser Leu Thr
         35                  40                  45

Ser Ser Leu Ser Leu Leu Leu Ser Pro Pro Pro Pro Pro Ser Leu Ser
     50                  55                  60

Ser Ser Ser Leu Cys Pro His Pro Ile Ala Phe Phe Phe Leu Leu Phe
 65                  70                  75                  80

Leu Phe Pro Ile Leu Thr Gln Asp Cys Phe Thr Val Ser Gln Val Lys
                 85                  90                  95

Phe Lys Leu Leu Glu Asp Phe Ser Thr Glu Arg Gln Trp Leu Thr Cys
            100                 105                 110

Lys Thr 




<210> 2440
<211> 125
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2440
Met Ala Glu Phe Pro Ser Lys Val Ser Thr Arg Thr Ser Ser Pro Ala
  1               5                  10                  15

Gln Gly Ala Glu Ala Ser Val Ser Ala Leu Arg Pro Asp Leu Gly Phe
             20                  25                  30

Val Arg Ser Arg Leu Gly Ala Leu Met Leu Leu Gln Leu Val Leu Gly
         35                  40                  45

Leu Leu Val Trp Ala Leu Ile Ala Asp Thr Pro Tyr His Leu Tyr Pro
     50                  55                  60

Ala Tyr Gly Trp Val Met Phe Val Ala Val Phe Leu Trp Leu Val Thr
 65                  70                  75                  80

Ile Val Leu Phe Asn Leu Tyr Leu Phe Gln Leu His Met Lys Leu Tyr
                 85                  90                  95

Met Val Pro Trp Pro Leu Val Leu Met Ile Phe Asn Ile Ser Gly Thr
            100                 105                 110

Val Leu Tyr Ile Thr Xaa Phe Ile Gly Cys Ser Ala Ala 
        115                 120                 125



<210> 2441
<211> 147
<212> PRT
<213> Homo sapiens

<400> 2441
Met Val Tyr Phe Val Ser Phe Leu Gly Thr Leu Ala Val Leu Pro Gly
  1               5                  10                  15

Asn Ile Val Ser Ala Leu Leu Met Asp Lys Ile Gly Arg Leu Arg Met
             20                  25                  30

Leu Ala Gly Ser Ser Val Met Ser Cys Val Ser Cys Phe Phe Leu Ser
         35                  40                  45

Phe Gly Asn Ser Glu Ser Ala Met Ile Ala Leu Leu Cys Leu Phe Gly
     50                  55                  60

Gly Val Ser Ile Ala Ser Trp Asn Ala Leu Asp Val Leu Thr Val Glu
 65                  70                  75                  80

Leu Tyr Pro Ser Asp Lys Arg Thr Thr Ala Phe Gly Phe Leu Asn Ala
                 85                  90                  95

Leu Cys Lys Leu Ala Ala Val Leu Gly Ile Ser Ile Phe Thr Ser Phe
            100                 105                 110

Val Gly Ile Thr Lys Ala Ala Pro Ile Leu Phe Ala Ser Ala Ala Leu
        115                 120                 125

Ala Leu Gly Ser Ser Leu Ala Leu Lys Leu Pro Glu Thr Arg Gly Gln
    130                 135                 140

Val Leu Gln 
145



<210> 2442
<211> 120
<212> PRT
<213> Homo sapiens

<400> 2442
Met Met Pro Ser Arg Thr Asn Leu Ala Thr Gly Ile Pro Ser Ser Lys
  1               5                  10                  15

Val Lys Tyr Ser Arg Leu Ser Ser Thr Asp Asp Gly Tyr Ile Asp Leu
             20                  25                  30

Gln Phe Lys Lys Thr Pro Pro Lys Ile Pro Tyr Lys Ala Ile Ala Leu
         35                  40                  45

Ala Thr Val Leu Phe Leu Ile Gly Ala Phe Leu Ile Ile Ile Gly Ser
     50                  55                  60

Leu Leu Leu Ser Gly Tyr Ile Ser Lys Gly Gly Ala Asp Arg Ala Val
 65                  70                  75                  80

Pro Val Leu Ile Ile Gly Ile Leu Val Phe Leu Pro Gly Phe Tyr His
                 85                  90                  95

Leu Arg Ile Ala Tyr Tyr Ala Ser Lys Gly Tyr Arg Gly Tyr Ser Tyr
            100                 105                 110

Asp Asp Ile Pro Asp Phe Asp Asp 
        115                 120



<210> 2443
<211> 218
<212> PRT
<213> Homo sapiens

<400> 2443
Met Val Ser Trp Met Ile Cys Arg Leu Val Val Leu Val Phe Gly Met
  1               5                  10                  15

Leu Cys Pro Ala Tyr Ala Ser Tyr Lys Ala Val Lys Thr Lys Asn Ile
             20                  25                  30

Arg Glu Tyr Val Arg Trp Met Met Tyr Trp Ile Val Phe Ala Leu Phe
         35                  40                  45

Met Ala Ala Glu Ile Val Thr Asp Ile Phe Ile Ser Trp Phe Pro Phe
     50                  55                  60

Tyr Tyr Glu Ile Lys Met Ala Phe Val Leu Trp Leu Leu Ser Pro Tyr
 65                  70                  75                  80

Thr Lys Gly Ala Ser Cys Phe Thr Ala Ser Leu Ser Thr Arg Pro Cys
                 85                  90                  95

Pro Ala Met Arg Arg Arg Ser Thr Arg Thr Ser Cys Arg Pro Arg Ser
            100                 105                 110

Ala Ala Thr Arg Pro Cys Ser Ala Ser Gly Ser Gly Ala Ser Thr Leu
        115                 120                 125

Pro Pro Pro Leu Leu Cys Arg Leu Pro Pro Arg Val Arg Gly Arg Trp
    130                 135                 140

Pro Ala Gly Cys Gly Ala Ser Pro Cys Arg Thr Cys Ala Pro Ser Leu
145                 150                 155                 160

Thr His Leu Pro Leu Pro Thr Met Thr Pro Ser Thr Trp Arg Thr Arg
                165                 170                 175

Cys Pro Thr Gly Gly His Pro Leu Gly Thr Gly Pro Gly Ala Cys Arg
            180                 185                 190

Thr Ala Thr Pro Arg Met Ser Val Gly Gln Ile Leu Arg Gln Ser Pro
        195                 200                 205

Gly Arg Gln Pro Gly Pro Glu Arg Ser Pro 
    210                 215



<210> 2444
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (44)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2444
Met Val Met Trp Phe Pro Gly Trp Leu Leu Gly Arg Gly Arg Ala Gly
  1               5                  10                  15

Ser Ser Arg Ser Cys Leu Ser Val Leu Ser Ser Val Cys Phe Pro Thr
             20                  25                  30

Thr Gln Pro Xaa Ala Trp Met Val Pro Ser Val Xaa Leu Ile Leu Xaa
         35                  40                  45

Cys Pro Gly Phe Ser Thr Glu Ile Ile Cys Val Gly Ser Leu Ser Val
     50                  55                  60

Pro Gly Gln Pro Glu Gln Leu Val Ala Pro Cys Leu Thr Tyr Leu Ser
 65                  70                  75                  80

Asn Cys Leu Gln Gly Met Ala His Gln Arg Gly Cys Gly Thr Leu Ser
                 85                  90                  95

Leu Pro Ser Leu Val Ser Phe Thr Val Lys Ser Gly Lys Gly Leu Leu
            100                 105                 110

Val Gly Val Arg 
        115



<210> 2445
<211> 336
<212> PRT
<213> Homo sapiens

<400> 2445
Met Leu Thr Trp Arg Ala Glu Gln Glu Gly Gly Met Gln Phe Trp Val
  1               5                  10                  15

Ser Ser Glu Ser Lys Leu Ser Asp Ser Trp Gln Pro Arg Ser Leu Asp
             20                  25                  30

Ile Glu Val Ala Ala Tyr Ala Leu Leu Ser His Phe Leu Gln Phe Gln
         35                  40                  45

Thr Ser Glu Gly Ile Pro Ile Met Arg Trp Leu Ser Arg Gln Arg Asn
     50                  55                  60

Ser Leu Gly Gly Phe Ala Ser Thr Gln Asp Thr Thr Val Ala Leu Lys
 65                  70                  75                  80

Ala Leu Ser Glu Phe Ala Ala Leu Met Asn Thr Glu Arg Thr Asn Ile
                 85                  90                  95

Gln Val Thr Val Thr Gly Pro Ser Ser Pro Ser Pro Val Lys Phe Leu
            100                 105                 110

Ile Asp Thr His Asn Arg Leu Leu Leu Gln Thr Ala Glu Leu Ala Val
        115                 120                 125

Val Gln Pro Met Ala Val Asn Ile Ser Ala Asn Gly Phe Gly Phe Ala
    130                 135                 140

Ile Cys Gln Leu Asn Val Val Tyr Asn Val Lys Ala Ser Gly Ser Ser
145                 150                 155                 160

Arg Arg Arg Arg Ser Ile Gln Asn Gln Glu Ala Phe Asp Leu Asp Val
                165                 170                 175

Ala Val Lys Glu Asn Lys Asp Asp Leu Asn His Val Asp Leu Asn Val
            180                 185                 190

Cys Thr Ser Phe Ser Gly Pro Gly Arg Ser Gly Met Ala Leu Met Glu
        195                 200                 205

Val Asn Leu Leu Ser Gly Phe Met Val Pro Ser Glu Ala Ile Ser Leu
    210                 215                 220

Ser Glu Thr Val Lys Lys Val Glu Tyr Asp His Gly Lys Leu Asn Leu
225                 230                 235                 240

Tyr Leu Asp Ser Val Asn Glu Thr Gln Phe Cys Val Asn Ile Pro Ala
                245                 250                 255

Val Arg Asn Phe Lys Val Ser Asn Thr Gln Asp Ala Ser Val Ser Ile
            260                 265                 270

Val Asp Tyr Tyr Glu Pro Arg Arg Gln Ala Val Arg Ser Tyr Asn Ser
        275                 280                 285

Glu Val Lys Leu Ser Ser Cys Asp Leu Cys Ser Asp Val Gln Gly Cys
    290                 295                 300

Arg Pro Cys Glu Asp Gly Ala Ser Gly Ser His His His Ser Ser Val
305                 310                 315                 320

Ile Phe Ile Phe Cys Phe Lys Leu Leu Tyr Phe Met Glu Leu Trp Leu
                325                 330                 335






<210> 2446
<211> 300
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2446
Met Ser Asn Pro Ser Ala Pro Pro Pro Tyr Glu Asp Arg Asn Pro Leu
  1               5                  10                  15

Tyr Pro Gly Pro Xaa Pro Pro Gly Gly Tyr Gly Gln Pro Ser Val Leu
             20                  25                  30

Pro Gly Gly Tyr Pro Ala Tyr Pro Gly Tyr Pro Gln Pro Gly Tyr Gly
         35                  40                  45

His Pro Ala Gly Tyr Pro Gln Pro Met Pro Pro Thr His Pro Met Pro
     50                  55                  60

Met Asn Tyr Gly Pro Gly His Gly Tyr Asp Gly Glu Glu Arg Ala Val
 65                  70                  75                  80

Ser Asp Ser Phe Gly Pro Gly Glu Trp Asp Asp Arg Lys Val Arg His
                 85                  90                  95

Thr Phe Ile Arg Lys Val Tyr Ser Ile Ile Ser Val Gln Leu Leu Ile
            100                 105                 110

Thr Val Ala Ile Ile Ala Ile Phe Thr Phe Val Glu Pro Val Ser Ala
        115                 120                 125

Phe Val Arg Arg Asn Val Ala Val Tyr Tyr Val Ser Tyr Ala Val Phe
    130                 135                 140

Val Val Thr Tyr Leu Ile Leu Ala Cys Cys Gln Gly Pro Arg Arg Arg
145                 150                 155                 160

Phe Pro Trp Asn Ile Ile Leu Leu Thr Leu Phe Thr Phe Ala Met Gly
                165                 170                 175

Phe Met Thr Gly Thr Ile Ser Ser Met Tyr Gln Thr Lys Ala Val Ile
            180                 185                 190

Ile Ala Met Ile Ile Thr Ala Val Val Ser Ile Ser Val Thr Ile Phe
        195                 200                 205

Cys Phe Gln Thr Lys Val Asp Phe Thr Ser Cys Thr Gly Leu Phe Cys
    210                 215                 220

Val Leu Gly Ile Val Leu Leu Val Thr Gly Ile Val Thr Ser Ile Val
225                 230                 235                 240

Leu Tyr Phe Gln Tyr Val Tyr Trp Leu His Met Leu Tyr Ala Ala Leu
                245                 250                 255

Gly Ala Ile Cys Phe Thr Leu Phe Leu Ala Tyr Asp Thr Gln Leu Val
            260                 265                 270

Leu Gly Asn Arg Lys His Thr Ile Ser Pro Glu Asp Tyr Ile Thr Gly
        275                 280                 285

Ala Leu Gln Ile Tyr Thr Asp Ile Ile Tyr Ile Phe 
    290                 295                 300



<210> 2447
<211> 156
<212> PRT
<213> Homo sapiens

<400> 2447
Met Gln Ile Gln Val Ala Gly Leu Leu Gln Phe Ala Val Pro Leu Phe
  1               5                  10                  15

Ser Thr Ala Glu Glu Asp Leu Leu Ala Ile Gln Leu Leu Leu Asn Ser
             20                  25                  30

Ser Glu Ser Ser Leu His Gln Leu Thr Ala Met Val Asp Cys Arg Gly
         35                  40                  45

Leu His Lys Asp Tyr Leu Asp Ala Leu Ala Gly Ile Cys Tyr Asp Gly
     50                  55                  60

Leu Gln Gly Leu Leu Tyr Leu Gly Leu Phe Ser Phe Leu Ala Ala Leu
 65                  70                  75                  80

Ala Phe Ser Thr Met Ile Cys Ala Gly Pro Arg Ala Trp Lys His Phe
                 85                  90                  95

Thr Thr Arg Asn Arg Asp Tyr Asp Asp Ile Asp Asp Asp Asp Pro Phe
            100                 105                 110

Asn Pro Gln Ala Trp Arg Met Ala Ala His Ser Pro Pro Arg Gly Gln
        115                 120                 125

Leu His Ser Phe Cys Ser Tyr Ser Ser Gly Leu Gly Ser Gln Thr Ser
    130                 135                 140

Leu Gln Pro Pro Ala Gln Thr Ile Ser Asn Ala Pro 
145                 150                 155



<210> 2448
<211> 137
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2448
Met Ser Met Ala Val Glu Thr Phe Gly Phe Phe Met Ala Thr Val Gly
  1               5                  10                  15

Leu Leu Met Leu Gly Val Thr Leu Pro Asn Ser Tyr Trp Arg Val Ser
             20                  25                  30

Thr Val His Gly Asn Val Ile Thr Thr Asn Thr Ile Phe Glu Asn Leu
         35                  40                  45

Trp Phe Ser Cys Ala Thr Asp Ser Leu Gly Val Tyr Asn Cys Trp Glu
     50                  55                  60

Phe Pro Ser Met Leu Ala Leu Ser Gly Tyr Ile Gln Ala Cys Arg Ala
 65                  70                  75                  80

Leu Met Ile Thr Ala Ile Leu Leu Gly Phe Leu Gly Leu Leu Leu Gly
                 85                  90                  95

Ile Ala Gly Leu Arg Cys Thr Asn Ile Gly Gly Leu Glu Leu Ser Arg
            100                 105                 110

Lys Ala Lys Leu Ala Ala Asn Ala Gly Pro Phe Gln Ile Leu Gly Arg
        115                 120                 125

Tyr Leu Arg Asp Gly Gly Xaa Ser Xaa 
    130                 135



<210> 2449
<211> 343
<212> PRT
<213> Homo sapiens

<400> 2449
Met Gln Pro Pro Pro Pro Gly Pro Leu Gly Asp Cys Leu Arg Asp Trp
  1               5                  10                  15

Glu Asp Leu Gln Gln Asp Phe Gln Asn Ile Gln Glu Thr His Arg Leu
             20                  25                  30

Tyr Arg Leu Lys Leu Glu Glu Leu Thr Lys Leu Gln Asn Asn Cys Thr
         35                  40                  45

Ser Ser Ile Thr Arg Gln Lys Lys Arg Leu Gln Glu Leu Ala Leu Ala
     50                  55                  60

Leu Lys Lys Cys Lys Pro Ser Leu Pro Ala Glu Ala Glu Gly Ala Ala
 65                  70                  75                  80

Gln Glu Leu Glu Asn Gln Met Lys Glu Arg Gln Gly Leu Phe Phe Asp
                 85                  90                  95

Met Glu Ala Tyr Leu Pro Lys Lys Asn Gly Leu Tyr Leu Ser Leu Val
            100                 105                 110

Leu Gly Asn Val Asn Val Thr Leu Leu Ser Lys Gln Ala Lys Phe Ala
        115                 120                 125

Tyr Lys Asp Glu Tyr Glu Lys Phe Lys Leu Tyr Leu Thr Ile Ile Leu
    130                 135                 140

Ile Leu Ile Ser Phe Thr Cys Arg Phe Leu Leu Asn Ser Arg Val Thr
145                 150                 155                 160

Asp Ala Ala Phe Asn Phe Leu Leu Val Trp Tyr Tyr Cys Thr Leu Thr
                165                 170                 175

Ile Arg Glu Ser Ile Leu Ile Asn Asn Gly Ser Arg Ile Lys Gly Trp
            180                 185                 190

Trp Val Phe His His Tyr Val Ser Thr Phe Leu Ser Gly Val Met Leu
        195                 200                 205

Thr Trp Pro Asp Gly Leu Met Tyr Gln Lys Phe Arg Asn Gln Phe Leu
    210                 215                 220

Ser Phe Ser Met Tyr Gln Ser Phe Val Gln Phe Leu Gln Tyr Tyr Tyr
225                 230                 235                 240

Gln Ser Gly Cys Leu Tyr Arg Leu Arg Ala Leu Gly Glu Arg His Thr
                245                 250                 255

Met Asp Leu Thr Val Glu Gly Phe Gln Ser Trp Met Trp Arg Gly Leu
            260                 265                 270

Thr Phe Leu Leu Pro Phe Leu Phe Phe Gly His Phe Trp Gln Leu Phe
        275                 280                 285

Asn Ala Leu Thr Leu Phe Asn Leu Ala Gln Asp Pro Gln Cys Lys Glu
    290                 295                 300

Trp Gln Val Leu Met Cys Gly Phe Pro Phe Leu Leu Leu Phe Leu Gly
305                 310                 315                 320

Asn Phe Phe Thr Thr Leu Arg Val Val His His Lys Phe His Ser Gln
                325                 330                 335

Arg His Gly Ser Lys Lys Asp 
            340



<210> 2450
<211> 210
<212> PRT
<213> Homo sapiens

<400> 2450
Met Ala Pro Leu Ala Gly Ala Met Met Leu Thr Leu Leu Leu Leu Cys
  1               5                  10                  15

Trp Cys Cys Phe Pro Gly Lys Ala Met Gln Tyr His Thr Gly Val Gln
             20                  25                  30

Thr Pro Glu Trp Lys Pro Arg Leu Val Trp Ser Cys Leu Gly Leu Tyr
         35                  40                  45

Ile Val Phe Leu Thr Ala Leu Glu Phe Lys Gln Glu Leu Trp Gly Leu
     50                  55                  60

Val Ile Val Ala Ala Gly Phe Ala Leu Leu Ala Arg Arg Val Val Leu
 65                  70                  75                  80

Ser Val Asp Trp Thr Leu Leu Leu Val Phe Met Ala Met Phe Ile Asp
                 85                  90                  95

Val His Leu Leu Thr Gln Leu Pro Ala Leu Gln Gly Val Leu Gly Asn
            100                 105                 110

Val Ser His Leu Ser Glu Pro Gly Leu Trp Leu Thr Ala Ile Gly Leu
        115                 120                 125

Ser Gln Val Ile Ser Asn Val Pro Ser Thr Ile Leu Leu Leu Asn Tyr
    130                 135                 140

Val Pro Pro Ser Leu Leu Leu Val Trp Ala Val Asn Val Gly Gly Phe
145                 150                 155                 160

Gly Leu Leu Pro Gly Ser Leu Ala Asn Leu Ile Ala Leu Arg Met Ala
                165                 170                 175

Asn Asp Arg Arg Ile Trp Trp Arg Phe His Leu Tyr Ser Ile Pro Met
            180                 185                 190

Leu Leu Trp Ala Ala Leu Val Gly Tyr Val Leu Leu Val Ile Leu Pro
        195                 200                 205

Ala Asn 
    210



<210> 2451
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2451
Met Ser Gln Ile Tyr Gly Leu Ile His Gly Asp Leu Cys Phe Ile Pro
  1               5                  10                  15

Asn Val Tyr Ala Ala Leu Phe Thr Ala Ala Leu Val Pro Leu Thr Cys
             20                  25                  30

Leu Val Val Val Phe Val Val Phe Ile His Ala Tyr Gln Val Lys Pro
         35                  40                  45

Gln Trp Lys Ala Tyr Asp Asp Val Phe Arg Gly Arg Thr Asn Ala Ala
     50                  55                  60

Glu Ile Pro Leu Ile Leu Tyr Leu Phe Ala Leu Ile Ser Val Thr Trp
 65                  70                  75                  80

Leu Trp Gly Gly Leu His Met Ala Tyr Arg His Phe Trp Met Leu Val
                 85                  90                  95

Leu Phe Val Ile Phe Asn Ser Leu Gln Gly Leu Tyr Val Phe Met Val
            100                 105                 110

Tyr Phe Ile Leu His Asn Gln Met Cys Cys Pro Met Lys Ala Ser Tyr
        115                 120                 125

Thr Val Glu Met Asn Gly His Pro Gly Pro Ser Thr Ala Phe Phe Thr
    130                 135                 140

Pro Gly Ser Gly Met Pro Pro Ala Gly Xaa Glu Ile Ser Lys Ser Thr
145                 150                 155                 160

Gln Asn Leu Asn Arg Trp Tyr Gly Gly Arg Cys His Leu Thr Gly Arg
                165                 170                 175

Glu His Pro Ser Lys Xaa Gly 
            180



<210> 2452
<211> 173
<212> PRT
<213> Homo sapiens

<400> 2452
Met Met Tyr Phe Cys Gln Met Leu Ala Val Val Glu Thr Ile Asn Ala
  1               5                  10                  15

Ala Ile Gly Val Thr Thr Ser Pro Val Leu Pro Ser Leu Ile Gln Leu
             20                  25                  30

Leu Gly Arg Asn Phe Ile Leu Phe Ile Ile Phe Gly Thr Met Glu Glu
         35                  40                  45

Met Gln Asn Lys Ala Val Val Phe Phe Val Phe Tyr Leu Trp Ser Ala
     50                  55                  60

Ile Glu Ile Phe Arg Tyr Ser Phe Tyr Met Leu Thr Cys Ile Asp Met
 65                  70                  75                  80

Asp Trp Lys Val Leu Thr Trp Leu Arg Tyr Thr Leu Trp Ile Pro Leu
                 85                  90                  95

Tyr Pro Leu Gly Cys Leu Ala Glu Ala Val Ser Val Ile Gln Ser Ile
            100                 105                 110

Pro Ile Phe Asn Glu Thr Gly Arg Phe Ser Phe Thr Leu Pro Tyr Pro
        115                 120                 125

Val Lys Ile Lys Val Arg Phe Ser Phe Phe Leu Gln Ile Tyr Leu Ile
    130                 135                 140

Met Ile Phe Leu Gly Leu Tyr Ile Asn Phe Arg His Leu Tyr Lys Gln
145                 150                 155                 160

Arg Arg Arg Arg Tyr Gly Gln Lys Lys Lys Lys Ile His 
                165                 170



<210> 2453
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2453
Met Asp Tyr Gly Cys Ala Gln Glu Ala Glu Gly Arg Met Cys Glu Asp
  1               5                  10                  15

Phe Gln Asp Glu Asp His Asp Ser Ala Ser Pro Asp Thr Ser Phe Ser
             20                  25                  30

Pro Tyr Asp Gly Asp Leu Thr Thr Thr Ser Ser Ser Leu Phe Ile Asp
         35                  40                  45

Ser Leu Thr Thr Glu Asp Asp Thr Lys Leu Asn Pro Tyr Ala Gly Gly
     50                  55                  60

Asp Gly Leu Gln Asn Asn Leu Ser Pro Lys Thr Lys Gly Thr Pro Val
 65                  70                  75                  80

His Leu Gly Thr Ile Val Gly Ile Val Leu Ala Val Leu Leu Val Ala
                 85                  90                  95

Ala Ile Ile Leu Ala Gly Ile Tyr Ile Asn Gly His Pro Thr Ser Asn
            100                 105                 110

Ala Ala Leu Phe Phe Ile Glu Arg Arg Pro His His Trp Pro Ala Met
        115                 120                 125

Lys Phe Pro Gln His Leu Xaa Ile Pro Pro Met Arg Xaa Trp Ser Leu
    130                 135                 140

Gly Pro 
145



<210> 2454
<211> 123
<212> PRT
<213> Homo sapiens

<400> 2454
Met Ser Ser Gly Gly Ser Pro Gly Cys Leu Arg Leu Ala Glu Gly Cys
  1               5                  10                  15

Pro Asn His Arg Ala Trp Val Arg Trp Asn Arg Arg Gln Pro His Ser
             20                  25                  30

Ala Phe Leu Ile Ala Ser His Leu Phe Leu Ser Val Leu Val Trp Phe
         35                  40                  45

Asn Ser Phe Gln Gly Leu Glu Leu Glu Ser Glu Asn Pro Arg His Leu
     50                  55                  60

Leu Trp Asn Val Cys Leu Val Val Leu Val Cys Pro Ser Ser Ser Leu
 65                  70                  75                  80

Ala Cys Arg Phe Gln Val Tyr Gln Arg Thr Phe Cys Ser Val Glu Ser
                 85                  90                  95

His Arg Thr Lys Arg Lys Ile Leu Gln Leu Phe Ala Asn Ile Leu Pro
            100                 105                 110

Tyr Leu Tyr Lys Gln Pro Tyr Thr Lys Lys His 
        115                 120



<210> 2455
<211> 136
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (135)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2455
Met Met Gly His Glu Val Lys Val Pro Leu Leu Glu Asn Phe Tyr Ala
  1               5                  10                  15

Asp Tyr Tyr Thr Thr Ala Ser Ile Ala Leu Val Ser Cys Leu Ala Met
             20                  25                  30

Cys Val Val Val Arg Phe Leu Gly Arg Lys Gly Arg Leu Leu Leu Phe
         35                  40                  45

Met Ile Leu Thr Ala Leu Ala Ser Leu Leu Gln Leu Gly Leu Leu Asn
     50                  55                  60

Leu Ile Gly Lys Tyr Ser Gln His Pro Asp Ser Gly Met Xaa Asp Ser
 65                  70                  75                  80

Val Lys Asp Lys Phe Ser Ile Ala Phe Ser Ile Val Gly His Val Cys
                 85                  90                  95

Leu Pro Cys Gly Gly Asp Leu Ser Val Phe Phe Cys Ala Glu Ile Thr
            100                 105                 110

Pro Thr Val Ile Lys Val Leu Pro Ala Trp Ala Gly Ser Cys His Pro
        115                 120                 125

Gly Leu Pro Ala Phe Leu Xaa Xaa 
    130                 135



<210> 2456
<211> 221
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (96)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2456
Met Ala Ala Ser Arg Pro Leu Ser Arg Phe Trp Glu Trp Gly Lys Asn
  1               5                  10                  15

Ile Val Cys Val Gly Arg Asn Tyr Ala Asp His Val Arg Glu Met Arg
             20                  25                  30

Ser Ala Val Leu Ser Glu Pro Val Leu Phe Leu Lys Pro Ser Thr Ala
         35                  40                  45

Tyr Ala Pro Glu Gly Ser Pro Ile Leu Met Pro Ala Tyr Thr Arg Asn
     50                  55                  60

Leu His His Glu Leu Glu Leu Gly Val Val Met Gly Lys Arg Cys Arg
 65                  70                  75                  80

Ala Val Pro Glu Ala Ala Ala Met Asp Tyr Val Gly Gly Tyr Ala Xaa
                 85                  90                  95

Cys Leu Asp Met Thr Ala Arg Asp Val Gln Asp Glu Cys Lys Lys Lys
            100                 105                 110

Gly Leu Pro Trp Thr Leu Ala Lys Ser Phe Thr Ala Ser Cys Pro Val
        115                 120                 125

Ser Ala Phe Val Pro Lys Glu Lys Ile Pro Asp Pro His Lys Leu Lys
    130                 135                 140

Leu Trp Leu Lys Val Asn Gly Glu Leu Arg Gln Glu Gly Glu Thr Ser
145                 150                 155                 160

Ser Met Ile Phe Xaa Ile Pro Tyr Ile Ile Ser Tyr Val Ser Lys Ile
                165                 170                 175

Ile Thr Leu Glu Glu Gly Asp Ile Ile Leu Thr Gly Thr Pro Lys Gly
            180                 185                 190

Val Gly Pro Val Lys Glu Asn Asp Glu Ile Glu Ala Gly Ile His Gly
        195                 200                 205

Leu Val Ser Met Thr Phe Lys Val Glu Lys Pro Glu Tyr 
    210                 215                 220



<210> 2457
<211> 152
<212> PRT
<213> Homo sapiens

<400> 2457
Met Glu Leu Pro Ala Val Asn Leu Lys Val Ile Leu Leu Gly His Trp
  1               5                  10                  15

Leu Leu Thr Thr Trp Gly Cys Ile Val Phe Ser Gly Ser Tyr Ala Trp
             20                  25                  30

Ala Asn Phe Thr Ile Leu Ala Leu Gly Val Trp Ala Val Ala Gln Arg
         35                  40                  45

Asp Ser Ile Asp Ala Ile Ser Met Phe Leu Gly Gly Leu Leu Ala Thr
     50                  55                  60

Ile Phe Leu Asp Ile Val His Ile Ser Ile Phe Tyr Pro Arg Val Ser
 65                  70                  75                  80

Leu Thr Asp Thr Gly Arg Phe Gly Val Gly Met Ala Ile Leu Ser Leu
                 85                  90                  95

Leu Leu Lys Pro Leu Ser Cys Cys Phe Val Tyr His Met Tyr Arg Glu
            100                 105                 110

Arg Gly Gly Phe Leu Gly Ser Ser Gln Asp Arg Ser Ala Tyr Gln Thr
        115                 120                 125

Ile Asp Ser Ala Glu Ala Pro Ala Asp Pro Phe Ala Val Pro Glu Gly
    130                 135                 140

Arg Ser Gln Asp Ala Arg Gly Tyr 
145                 150



<210> 2458
<211> 136
<212> PRT
<213> Homo sapiens

<400> 2458
Met Glu Asp His Ile Asn Pro Asn Cys His Gly Arg Trp Leu Lys Ala
  1               5                  10                  15

Thr Glu Val Asn Tyr His Asp Ser Gly Ala Thr Ile Arg Phe Ser Ser
             20                  25                  30

Ser Trp Gly Asp Gly Glu Ile Glu Ser His Leu Met Gly Ala Phe Asn
         35                  40                  45

Val Ser Asn Leu Leu Leu Ala Leu Ala Thr Leu Leu Ala Leu Gly Tyr
     50                  55                  60

Pro Leu Ala Asp Leu Leu Lys Thr Ala Ala Arg Leu Gln Pro Val Cys
 65                  70                  75                  80

Gly Arg Met Glu Val Phe Thr Ala Pro Gly Lys Pro Thr Val Val Val
                 85                  90                  95

Asp Tyr Ala His Thr Pro Asp Ala Leu Glu Lys Pro Tyr Arg Arg Arg
            100                 105                 110

Val Cys Thr Val Arg Ala Ser Cys Gly Val Ser Leu Ala Val Val Ala
        115                 120                 125

Ile Ala Ile Lys Val Ser Val His 
    130                 135



<210> 2459
<211> 181
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (175)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2459
Met Pro His Ser Ser Leu His Pro Ser Ile Pro Cys Pro Arg Gly His
  1               5                  10                  15

Gly Ala Gln Lys Ala Ala Leu Val Leu Leu Ser Ala Cys Leu Val Thr
             20                  25                  30

Leu Trp Gly Leu Gly Glu Pro Pro Glu His Thr Leu Arg Tyr Leu Val
         35                  40                  45

Leu His Leu Ala Ser Leu Gln Leu Gly Leu Leu Leu Asn Gly Val Cys
     50                  55                  60

Ser Leu Ala Glu Glu Leu Arg His Ile His Ser Arg Tyr Arg Gly Ser
 65                  70                  75                  80

Tyr Trp Arg Thr Val Arg Ala Cys Leu Gly Cys Pro Leu Arg Arg Gly
                 85                  90                  95

Ala Leu Leu Leu Leu Ser Ile Tyr Phe Tyr Tyr Ser Leu Pro Asn Ala
            100                 105                 110

Val Gly Pro Pro Phe Thr Trp Met Leu Ala Leu Leu Gly Leu Ser Gln
        115                 120                 125

Ala Leu Asn Ile Leu Leu Gly Leu Lys Gly Leu Ala Pro Ala Glu Ile
    130                 135                 140

Ser Ala Val Cys Glu Lys Xaa Asn Phe Asn Val Ala His Gly Leu Ala
145                 150                 155                 160

Trp Ser Tyr Tyr Ile Gly Tyr Leu Arg Leu Ile Leu Pro Lys Xaa Gln
                165                 170                 175

Gly Arg Ile Arg Thr 
            180



<210> 2460
<211> 109
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (6)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2460
Met Ala Tyr Val Phe Xaa Gly Ala Tyr Val Pro Leu Ser Cys Arg Ile
  1               5                  10                  15

Ile Glu Gln Val Leu Glu Arg Arg Ser Trp Gln Gly Leu Asp Glu Val
             20                  25                  30

Val Arg Leu Leu Asn Cys Ser Asp Phe Ala Phe Thr Asp Met Thr Lys
         35                  40                  45

Glu Asp Lys Ala Ser Ser Glu Ser Leu Arg Leu Ile Leu Val Val Phe
     50                  55                  60

Leu Gly Gly Cys Thr Phe Ser Glu Ile Ser Ala Leu Arg Phe Leu Gly
 65                  70                  75                  80

Arg Glu Lys Gly Tyr Arg Phe Ile Phe Leu Thr Thr Ala Val Thr Asn
                 85                  90                  95

Ser Ala Arg Leu Met Glu Ala Met Ser Glu Val Lys Ala 
            100                 105



<210> 2461
<211> 197
<212> PRT
<213> Homo sapiens

<400> 2461
Met Glu Pro Leu Cys Asn Gly Asn Leu Pro Thr Ser Met His Thr Leu
  1               5                  10                  15

Asp His Leu His Gly Val Ser Asn Arg Ala Ser Leu His Tyr Thr Gly
             20                  25                  30

Glu Ser Gln Leu Thr Glu Val Leu Gln Asn Leu Gly Lys Asp Gln Tyr
         35                  40                  45

Pro Gln Gln Ser Leu Glu Gln Ile Gly Thr Arg Ile Ala Lys Val Leu
     50                  55                  60

Glu Lys Asn Gln Thr Ser Trp Val Leu Ser Ser Met Ala Ala Leu Tyr
 65                  70                  75                  80

Trp Arg Val Lys Gly Gln Gly Lys Lys Ala Ile Asp Cys Leu Arg Gln
                 85                  90                  95

Ala Leu His Tyr Ala Pro His Gln Met Lys Asp Val Pro Leu Ile Ser
            100                 105                 110

Leu Ala Asn Ile Leu His Asn Ala Lys Leu Trp Asn Asp Ala Val Ile
        115                 120                 125

Val Ala Thr Met Ala Val Glu Ile Ala Pro His Phe Ala Val Asn His
    130                 135                 140

Phe Thr Leu Gly Asn Val Tyr Val Ala Met Glu Glu Phe Glu Lys Ala
145                 150                 155                 160

Leu Val Trp Tyr Glu Ser Thr Leu Lys Leu Gln Pro Glu Phe Val Pro
                165                 170                 175

Ala Lys Asn Arg Ile Gln Thr Ile Gln Cys His Leu Met Leu Lys Lys
            180                 185                 190

Gly Arg Arg Ser Pro 
        195



<210> 2462
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (50)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2462
Met Leu Gly Ser Leu Phe Phe Cys Leu Ser Val Cys Glu Trp Pro Val
  1               5                  10                  15

Cys Phe Phe Asn Trp Ser Glu Trp His Leu Ala His Pro His Ser His
             20                  25                  30

Leu Lys His Cys Gly Lys Ser Ser Pro Ser Ile Ser Ser Asn Ser Thr
         35                  40                  45

Thr Xaa His Ile Xaa Lys Asn Ser Leu Gly Leu Asp Phe Ile Met Val
     50                  55                  60

Leu Ala Ala Ile Leu Cys Ile Leu Ser Arg Arg Asn Ile Pro Pro Ser
 65                  70                  75                  80

Ala Pro Thr Leu Ser Leu Thr Phe Arg Ser Gly Ser Ser Ser Lys Leu
                 85                  90                  95

Ser Val Leu Lys Ala Ser Ser Met Ile Thr Ser His 
            100                 105



<210> 2463
<211> 149
<212> PRT
<213> Homo sapiens

<400> 2463
Met Arg Arg Glu Asp Pro Ala Leu Val Glu Leu Thr Arg Pro Arg Arg
  1               5                  10                  15

Ser Ser Leu Ser Thr Ser Val Arg Ala Trp Gly Ser Trp Trp Leu Leu
             20                  25                  30

Thr Met Gly Asp Ala Gly Glu Val Ala Gln Gly Ser Ala His Val Ser
         35                  40                  45

Pro Cys Ser Ser Arg Val Ile Phe Leu Met Phe Gly Ser Trp Ser Leu
     50                  55                  60

Phe Pro Leu Ala Phe His Pro His Gly Ala Glu Thr Val Ala Pro Gly
 65                  70                  75                  80

Ser Arg Lys Gly Ile Glu Val Gly Arg Gln Lys Ser Leu Asp Cys Ser
                 85                  90                  95

Leu Phe Trp Glu Thr Tyr Met Leu Arg Ser Thr Glu Ile Gln Glu Thr
            100                 105                 110

Lys Ala Leu Leu Ser Arg Ala Ile Leu Trp Leu Phe Leu Glu Ala Gln
        115                 120                 125

Glu Cys Gly Cys Lys Arg Lys Gly Ala Gly Gly Arg Ser Gly Gly Gln
    130                 135                 140

Gly Cys Ser Leu Cys 
145



<210> 2464
<211> 175
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2464
Met Pro Val Thr Val Thr Arg Thr Thr Ile Thr Thr Thr Thr Thr Ser
  1               5                  10                  15

Ser Ser Gly Leu Gly Ser Pro Met Ile Val Gly Ser Pro Arg Ala Leu
             20                  25                  30

Thr Gln Pro Leu Gly Leu Leu Arg Leu Leu Gln Leu Val Ser Thr Cys
         35                  40                  45

Val Ala Phe Ser Leu Val Ala Ser Val Gly Ala Trp Thr Gly Ser Met
     50                  55                  60

Gly Asn Trp Ser Met Phe Thr Trp Cys Phe Cys Phe Ser Val Thr Leu
 65                  70                  75                  80

Ile Ile Leu Ile Val Glu Leu Cys Gly Leu Gln Ala Arg Phe Pro Leu
                 85                  90                  95

Ser Trp Arg Asn Phe Pro Ile Thr Phe Ala Cys Tyr Ala Xaa Leu Phe
            100                 105                 110

Cys Leu Ser Ala Xaa Ile Ile Tyr Pro Thr Thr Tyr Val Gln Xaa Leu
        115                 120                 125

Ser His Gly Arg Ser Arg Asp His Ala Ile Ala Ala Pro Ser Ser Pro
    130                 135                 140

Ala Ser Arg Val Trp Leu Thr Pro Pro Lys Trp Pro Gly Pro Gly Pro
145                 150                 155                 160

Gly Pro Ala Arg Ser Leu Ala Ile Trp Xaa Pro Tyr Pro Gly Cys 
                165                 170                 175



<210> 2465
<211> 398
<212> PRT
<213> Homo sapiens

<400> 2465
Met Arg Lys Arg Thr Glu Pro Val Ala Leu Glu His Glu Arg Cys Ala
  1               5                  10                  15

Ala Ala Gly Ser Ser Ser Ser Gly Ser Ala Ala Ala Ala Leu Asp Ala
             20                  25                  30

Asp Cys Arg Leu Lys Gln Asn Leu Arg Leu Thr Gly Pro Ala Ala Ala
         35                  40                  45

Glu Pro Arg Cys Ala Ala Asp Ala Gly Met Lys Arg Ala Leu Gly Arg
     50                  55                  60

Arg Lys Gly Val Trp Leu Arg Leu Arg Lys Ile Leu Phe Cys Val Leu
 65                  70                  75                  80

Gly Leu Tyr Ile Ala Ile Pro Phe Leu Ile Lys Leu Cys Pro Gly Ile
                 85                  90                  95

Gln Ala Lys Leu Ile Phe Leu Asn Phe Val Arg Val Pro Tyr Phe Ile
            100                 105                 110

Asp Leu Lys Lys Pro Gln Asp Gln Gly Leu Asn His Thr Cys Asn Tyr
        115                 120                 125

Tyr Leu Gln Pro Glu Glu Asp Val Thr Ile Gly Val Trp His Thr Val
    130                 135                 140

Pro Ala Val Trp Trp Lys Asn Ala Gln Gly Lys Asp Gln Met Trp Tyr
145                 150                 155                 160

Glu Asp Ala Leu Ala Ser Ser His Pro Ile Ile Leu Tyr Leu His Gly
                165                 170                 175

Asn Ala Gly Thr Arg Gly Gly Asp His Arg Val Glu Leu Tyr Lys Val
            180                 185                 190

Leu Ser Ser Leu Gly Tyr His Val Val Thr Phe Asp Tyr Arg Gly Trp
        195                 200                 205

Gly Asp Ser Val Gly Thr Pro Ser Glu Arg Gly Met Thr Tyr Asp Ala
    210                 215                 220

Leu His Val Phe Asp Trp Ile Lys Ala Arg Ser Gly Asp Asn Pro Val
225                 230                 235                 240

Tyr Ile Trp Gly His Ser Leu Gly Thr Gly Val Ala Thr Asn Leu Val
                245                 250                 255

Arg Arg Leu Cys Glu Arg Glu Thr Pro Pro Asp Ala Leu Ile Leu Glu
            260                 265                 270

Ser Pro Phe Thr Asn Ile Arg Glu Glu Ala Lys Ser His Pro Phe Ser
        275                 280                 285

Val Ile Tyr Arg Tyr Phe Pro Gly Phe Asp Trp Phe Phe Leu Asp Pro
    290                 295                 300

Ile Thr Ser Ser Gly Ile Lys Phe Ala Asn Asp Glu Asn Val Lys His
305                 310                 315                 320

Ile Ser Cys Pro Leu Leu Ile Leu His Ala Glu Asp Asp Pro Val Val
                325                 330                 335

Pro Phe Gln Leu Gly Arg Lys Leu Tyr Ser Ile Ala Ala Pro Ala Arg
            340                 345                 350

Ser Phe Arg Asp Phe Lys Val Gln Phe Val Pro Phe His Ser Asp Leu
        355                 360                 365

Gly Tyr Arg His Lys Tyr Ile Tyr Lys Ser Pro Glu Leu Pro Arg Ile
    370                 375                 380

Leu Arg Glu Phe Leu Gly Lys Ser Glu Pro Glu His Gln His 
385                 390                 395



<210> 2466
<211> 189
<212> PRT
<213> Homo sapiens

<400> 2466
Met Gln Ala Thr Ala Thr Thr Leu Asp His Glu Gln Glu Tyr Thr Pro
  1               5                  10                  15

Ile Asn Ser Arg Asn Lys Val Leu Val Ala Ser Leu Ile Gly Thr Ala
             20                  25                  30

Ile Glu Phe Phe Asp Phe Tyr Ile Tyr Ala Thr Ala Ala Val Ile Val
         35                  40                  45

Phe Pro His Ile Phe Phe Pro Gln Gly Asp Pro Thr Ala Ala Thr Leu
     50                  55                  60

Gln Ser Leu Ala Thr Phe Ala Ile Ala Phe Val Ala Arg Pro Ile Gly
 65                  70                  75                  80

Ser Ala Val Phe Gly His Phe Gly Asp Arg Val Gly Arg Lys Ala Thr
                 85                  90                  95

Leu Val Ala Ser Leu Leu Thr Met Gly Ile Ser Thr Val Val Ile Gly
            100                 105                 110

Leu Leu Pro Gly Tyr Ala Thr Ile Gly Ile Phe Ala Pro Leu Leu Leu
        115                 120                 125

Ala Leu Ala Arg Phe Gly Gln Gly Leu Gly Leu Gly Gly Pro Val Pro
    130                 135                 140

Asn Ser Pro Tyr Ser Glu Ser Tyr Tyr Asn Ser Leu Ala Val Val Leu
145                 150                 155                 160

Gln Arg Arg Asp Trp Glu Asn Pro Gly Val Thr Gln Leu Asn Arg Leu
                165                 170                 175

Ala Asp Ile Pro Phe Arg Gln Ala Gly Val Ile Ala Lys 
            180                 185



<210> 2467
<211> 113
<212> PRT
<213> Homo sapiens

<400> 2467
Met Ala Gly Pro Ala Ala Ala Phe Arg Arg Leu Gly Ala Leu Ser Gly
  1               5                  10                  15

Ala Ala Ala Leu Gly Phe Ala Ser Tyr Gly Ala His Gly Ala Gln Phe
             20                  25                  30

Pro Asp Ala Tyr Gly Lys Glu Leu Phe Asp Lys Ala Asn Lys His His
         35                  40                  45

Phe Leu His Ser Leu Ala Leu Leu Gly Val Pro His Cys Arg Lys Pro
     50                  55                  60

Leu Trp Ala Gly Leu Leu Leu Ala Ser Gly Thr Thr Leu Phe Cys Thr
 65                  70                  75                  80

Ser Phe Tyr Tyr Gln Ala Leu Ser Gly Asp Pro Ser Ile Gln Thr Leu
                 85                  90                  95

Ala Pro Ala Gly Gly Thr Leu Leu Leu Leu Gly Trp Leu Ala Leu Ala
            100                 105                 110

Leu 




<210> 2468
<211> 127
<212> PRT
<213> Homo sapiens

<400> 2468
Met Arg Gln Arg Glu Leu Gln Val Gly Ile Pro Val Ala Asp Glu Ala
  1               5                  10                  15

Gly Gln Arg Leu Gly Tyr Ser Val Thr Ala Ala Lys Gln Gly Ile Phe
             20                  25                  30

Gln Val Val Ile Ser Arg Ile Cys Met Ala Ile Pro Ala Met Ala Ile
         35                  40                  45

Pro Pro Leu Ile Met Asp Thr Leu Glu Lys Lys Asp Phe Leu Lys Arg
     50                  55                  60

Arg Pro Trp Leu Gly Ala Pro Leu Gln Val Gly Leu Val Gly Phe Cys
 65                  70                  75                  80

Leu Val Phe Ala Thr Pro Leu Cys Cys Ala Leu Phe Pro Gln Lys Ser
                 85                  90                  95

Ser Ile His Ile Ser Asn Leu Glu Pro Glu Leu Arg Ala Gln Ile His
            100                 105                 110

Glu Gln Asn Pro Ser Val Glu Val Val Tyr Tyr Asn Lys Gly Leu 
        115                 120                 125



<210> 2469
<211> 271
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (214)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2469
Met His Cys Phe Ser Ile Met Val Thr Pro Asp Pro Ser Thr Pro Ser
  1               5                  10                  15

Arg Leu Ala Cys His Val Met His Leu Ser Ser His Arg Leu Asp Glu
             20                  25                  30

Tyr Trp Asp Arg Gln Arg Asn Arg His Arg Met Val Lys Val Asp Pro
         35                  40                  45

Glu Thr Arg Tyr Met Ser Leu Ala Val Cys Glu Leu Asp Gln Pro Gly
     50                  55                  60

Leu Gly Pro Leu Val Ala Ala Ala Cys Ser Asp Gly Ala Val Arg Leu
 65                  70                  75                  80

Phe Leu Leu Gln Asp Ser Gly Arg Ile Leu Gln Leu Leu Ala Glu Thr
                 85                  90                  95

Phe His His Lys Arg Cys Val Leu Lys Val His Ser Phe Thr His Glu
            100                 105                 110

Ala Pro Asn Gln Arg Arg Arg Leu Leu Leu Cys Ser Ala Ala Thr Asp
        115                 120                 125

Gly Ser Leu Ala Phe Trp Asp Leu Thr Thr Met Leu Asp His Asp Ser
    130                 135                 140

Thr Val Leu Glu Pro Pro Val Asp Pro Gly Leu Pro Tyr Arg Leu Gly
145                 150                 155                 160

Thr Pro Ser Leu Thr Leu Gln Ala His Ser Cys Gly Ile Asn Ser Leu
                165                 170                 175

His Thr Leu Pro Thr Arg Glu Gly His His Leu Val Ala Ser Gly Ser
            180                 185                 190

Glu Asp Gly Ser Leu His Val Phe Val Leu Ala Val Glu Met Leu Gln
        195                 200                 205

Leu Glu Glu Ala Val Xaa Glu Ala Gly Leu Val Pro Gln Leu Arg Val
    210                 215                 220

Leu Glu Glu Tyr Ser Val Pro Cys Ala His Ala Ala His Val Thr Gly
225                 230                 235                 240

Leu Lys Ile Leu Ser Pro Ser Ile Met Val Ser Ala Phe Ile Asp Gln
                245                 250                 255

Arg Leu Thr Phe Trp Arg Leu Gly His Gly Glu Pro Thr Phe Met 
            260                 265                 270



<210> 2470
<211> 201
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2470
Met Asp Ala Asp Leu Leu Ile Asp Xaa Leu Ala Asp Leu Arg Asp Ser
  1               5                  10                  15

Glu Val Ala Ala His Leu Leu Gln Val Cys Cys Tyr His Leu Pro Leu
             20                  25                  30

Met Gln Val Glu Leu Pro Ile Ser Leu Leu Thr Arg Leu Ala Leu Met
         35                  40                  45

Asp Pro Thr Ser Xaa Asn Gln Phe Xaa Asn Thr Val Ser Ala Ser Pro
     50                  55                  60

Arg Thr Ile Val Ser Phe Leu Ser Val Ala Leu Leu Ser Asp Gln Pro
 65                  70                  75                  80

Leu Leu Thr Ser Asp Leu Leu Ser Leu Leu Ala His Thr Ala Arg Val
                 85                  90                  95

Leu Ser Pro Ser His Leu Ser Phe Ile Gln Glu Leu Leu Ala Gly Ser
            100                 105                 110

Asp Glu Ser Tyr Arg Pro Leu Arg Ser Ser Trp Ala Thr Gln Arg Xaa
        115                 120                 125

Leu Cys Gly His Thr Leu Ile Gly Ser Trp Asp Thr Cys Ser Asn Thr
    130                 135                 140

Ala Trp Pro Cys Val Gly His Cys Arg Ala Ser Leu Asp Cys Ser Ala
145                 150                 155                 160

Phe Cys Cys Leu Gly Leu Glu Thr Arg Ile Leu Leu Cys Gly Ala Val
                165                 170                 175

Pro Ala Leu Leu Trp Ala Met Gln Pro Thr Arg Leu Val Leu Trp Asp
            180                 185                 190

Leu Pro Trp Gln Leu Gln Cys Pro Val 
        195                 200



<210> 2471
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (90)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2471
Met Lys Pro Arg Trp Gly Ser Ala Pro Glu Val Ser Ser Phe Leu Pro
  1               5                  10                  15

Leu Ile Ala Phe Pro Thr Ser Leu Ser Phe Pro Tyr Ser His Gln Ser
             20                  25                  30

Ala Val Trp Gly Ser Cys Pro Cys Pro Leu Leu Thr Phe Pro Phe Val
         35                  40                  45

Ser Phe Pro Ser Ser Thr Arg Ser Ile Phe Leu Ile Leu Leu Gly Xaa
     50                  55                  60

Met Val Cys Trp Phe Thr Cys Ile Ser His Ser Lys Thr Met Ala Lys
 65                  70                  75                  80

Ile Leu Cys Asn Tyr Leu Leu Ser Lys Xaa Ile Cys Ser Cys Ser Leu
                 85                  90                  95

Ser Phe Tyr Ser Ser Asp Val Asn His Phe Tyr Phe Leu Thr Leu Lys
            100                 105                 110

Glu Asn Ala Phe Ile Ile Leu Lys Lys Ile Asn 
        115                 120



<210> 2472
<211> 183
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2472
Met Ser Cys Gln Leu Leu Val Asn Ala Glu Gly Thr Asp Cys Leu Glu
  1               5                  10                  15

Ala Lys Glu Lys Val His Val Ile Gly Asn Arg Leu Lys Leu Leu Leu
             20                  25                  30

Lys Glu Val Ser Arg His Ile Lys Glu Leu Glu Lys Leu Leu Asp Val
         35                  40                  45

Ser Ser Ser Gln Gln Asp Leu Ser Ser Trp Ser Ser Ala Asp Glu Leu
     50                  55                  60

Asp Thr Ser Gly Ser Val Ser Pro Thr Ser Gly Arg Ser Thr Pro Asn
 65                  70                  75                  80

Arg Gln Lys Thr Pro Arg Gly Lys Cys Ser Leu Ser Gln Pro Gly Pro
                 85                  90                  95

Ser Val Ser Ser Pro His Ser Arg Ser Thr Lys Gly Gly Ser Asp Ser
            100                 105                 110

Ser Leu Ser Glu Pro Gly Pro Gly Arg Ser Gly Arg Gly Phe Xaa Phe
        115                 120                 125

Arg Val Leu Arg Ala Ala Leu Pro Leu Gln Leu Leu Leu Leu Leu Leu
    130                 135                 140

Ile Gly Leu Ala Cys Leu Val Pro Met Ser Glu Glu Asp Tyr Ser Cys
145                 150                 155                 160

Ala Leu Xaa Asn Asn Phe Ala Arg Ser Phe His Pro Met Leu Arg Tyr
                165                 170                 175

Thr Asn Gly Pro Pro Pro Leu 
            180



<210> 2473
<211> 279
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (266)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2473
Met Glu Ala Val Val Asn Leu Tyr Gln Glu Val Met Lys His Ala Asp
  1               5                  10                  15

Pro Arg Ile Gln Gly Tyr Pro Leu Met Gly Ser Pro Leu Leu Met Thr
             20                  25                  30

Ser Ile Leu Leu Thr Tyr Val Tyr Phe Val Leu Ser Leu Gly Pro Arg
         35                  40                  45

Ile Met Ala Asn Arg Lys Pro Phe Gln Leu Arg Gly Phe Met Ile Val
     50                  55                  60

Tyr Asn Phe Ser Leu Val Ala Leu Ser Leu Tyr Ile Val Tyr Glu Phe
 65                  70                  75                  80

Leu Met Ser Gly Trp Leu Ser Thr Tyr Thr Trp Arg Cys Asp Pro Val
                 85                  90                  95

Asp Tyr Ser Asn Ser Pro Glu Ala Leu Arg Met Val Arg Val Ala Trp
            100                 105                 110

Leu Phe Leu Phe Ser Lys Phe Ile Glu Leu Met Asp Thr Val Ile Phe
        115                 120                 125

Ile Leu Arg Lys Lys Asp Gly Gln Val Thr Phe Leu His Val Phe His
    130                 135                 140

His Ser Val Leu Pro Trp Ser Trp Trp Trp Gly Val Lys Ile Ala Pro
145                 150                 155                 160

Gly Gly Met Gly Ser Phe His Ala Met Ile Asn Ser Ser Val His Val
                165                 170                 175

Ile Met Tyr Leu Tyr Tyr Gly Leu Ser Ala Phe Gly Pro Val Ala Gln
            180                 185                 190

Pro Tyr Leu Trp Trp Lys Lys His Met Thr Ala Ile Gln Leu Ile Gln
        195                 200                 205

Phe Val Leu Val Ser Leu His Ile Ser Gln Tyr Tyr Phe Met Ser Ser
    210                 215                 220

Cys Asn Tyr Gln Tyr Pro Val Ile Ile His Leu Ile Trp Asp Val Trp
225                 230                 235                 240

His His Leu Leu His Ala Val Leu Gln Leu Leu Val Ser Leu Leu Tyr
                245                 250                 255

Gln Gly Gln Ala Ala Ala Pro Cys Thr Xaa Gln Asn Gly Ala Pro Gly
            260                 265                 270

Ile Ala Lys Val Lys Ala Asn 
        275



<210> 2474
<211> 153
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2474
Met Glu Ala Val Val Asn Leu Tyr Gln Glu Val Met Lys His Ala Asp
  1               5                  10                  15

Pro Arg Ile Gln Gly Tyr Pro Leu Met Gly Ser Pro Leu Leu Met Thr
             20                  25                  30

Ser Ile Leu Leu Thr Tyr Val Tyr Phe Val Leu Ser Leu Gly Pro Arg
         35                  40                  45

Ile Met Ala Asn Arg Lys Pro Phe Gln Leu Arg Gly Phe Met Ile Val
     50                  55                  60

Tyr Asn Phe Ser Leu Val Ala Leu Ser Leu Xaa Ala Ser Leu Glu Leu
 65                  70                  75                  80

Val Val Gly Gly Lys Asp Cys Pro Gly Arg Asn Gly Leu Phe Pro Cys
                 85                  90                  95

His Asp Lys Leu Phe Arg Ala Cys His Asn Val Pro Val Leu Arg Ile
            100                 105                 110

Ile Cys Leu Trp Pro Cys Gly Thr Thr Leu Pro Leu Val Glu Lys Ala
        115                 120                 125

His Asp Ser His Ser Ala Asp Pro Val Cys Pro Gly Leu Thr Ala His
    130                 135                 140

Leu Pro Val Leu Leu Tyr Val Gln Leu 
145                 150



<210> 2475
<211> 223
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (88)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (95)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (102)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2475
Met Phe Tyr Leu Ala Asn Val Cys Gly Cys Ala Val Ser Leu Leu Gly
  1               5                  10                  15

Leu Val Glu Ser Val Leu Asp Val Phe Gly Ala Asp Ala Thr Gly Pro
             20                  25                  30

Ser Gly Leu Arg Val Leu Pro Gln Gly Tyr Gly Trp Asn Leu Leu Tyr
         35                  40                  45

Gly Ser Leu Leu Leu Gly Leu Val Gly Gly Val Cys Thr Leu Gly Ala
     50                  55                  60

Gly Leu Tyr Ala Arg Ala Ser Phe Leu Thr Phe Leu Leu Val Ser Gly
 65                  70                  75                  80

Ser Leu Ala Ser Val Leu Ile Xaa Phe Val Ala Val Gly Pro Xaa Asp
                 85                  90                  95

Ile Arg Leu Thr Pro Xaa Pro Gly Pro Asn Gly Ser Ser Leu Pro Pro
            100                 105                 110

Arg Phe Gly His Phe Thr Gly Phe Asn Ser Ser Thr Leu Lys Asp Asn
        115                 120                 125

Leu Gly Ala Gly Tyr Ala Glu Asp Tyr Thr Thr Gly Ala Val Met Asn
    130                 135                 140

Phe Ala Ser Val Phe Ala Val Leu Phe Asn Gly Cys Thr Gly Ile Met
145                 150                 155                 160

Ala Gly Ala Asn Met Ser Gly Glu Leu Lys Asp Pro Ser Arg Ala Ile
                165                 170                 175

Pro Leu Gly Thr Ile Val Ala Val Ala Tyr Xaa Phe Xaa Val Tyr Val
            180                 185                 190

Leu Leu Phe Phe Ser Gln Phe Thr Cys Asp Arg Xaa Cys Cys Lys Lys
        195                 200                 205

Ile Trp Gly Leu Arg Gly Asn Lys Leu Leu Ala Pro Thr Gly Val 
    210                 215                 220



<210> 2476
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2476
Met Pro Pro Ser Trp Ile Gln Trp Trp Ser Thr Ser Asn Trp Arg Gln
  1               5                  10                  15

Pro Leu Gln Arg Leu Leu Trp Gly Leu Glu Gly Ile Leu Tyr Leu Leu
             20                  25                  30

Leu Ala Leu Met Leu Cys His Ala Leu Phe Thr Thr Gly Ser His Leu
         35                  40                  45

Leu Ser Ser Leu Trp Pro Val Val Ala Ala Val Trp Arg His Leu Leu
     50                  55                  60

Pro Ala Leu Leu Leu Leu Val Leu Ser Ala Leu Pro Ala Leu Leu Phe
 65                  70                  75                  80

Thr Xaa Ser Phe Leu Leu Leu Phe Ser Thr Leu Leu Ser Leu Val Gly
                 85                  90                  95

Leu Leu Thr Xaa Met Thr His Pro Gly Asp Thr Gln Asp Leu Asp Gln
            100                 105                 110






<210> 2477
<211> 176
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (162)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (176)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2477
Met Ala Pro Arg Gly Lys Arg Leu Ser Ser Thr Pro Leu Glu Ile Leu
  1               5                  10                  15

Phe Phe Leu Asn Gly Trp Tyr Asn Ala Thr Tyr Phe Leu Leu Glu Leu
             20                  25                  30

Phe Ile Phe Leu Tyr Lys Gly Val Leu Leu Pro Tyr Pro Thr Ala Asn
         35                  40                  45

Leu Val Leu Asp Val Val Met Leu Leu Leu Tyr Leu Gly Ile Glu Val
     50                  55                  60

Ile Arg Leu Phe Phe Gly Thr Lys Gly Asn Leu Cys Gln Arg Lys Met
 65                  70                  75                  80

Pro Leu Ser Ile Ser Val Ala Leu Thr Phe Pro Ser Ala Met Met Ala
                 85                  90                  95

Ser Tyr Tyr Leu Leu Leu Gln Thr Tyr Val Leu Arg Leu Glu Ala Ile
            100                 105                 110

Met Asn Gly Ile Leu Leu Phe Phe Cys Gly Phe Ser Ser Ala Gln Thr
        115                 120                 125

Phe Gly Gln Ala Thr Gln His Lys Ala Ser Gly Tyr His Leu Leu Asn
    130                 135                 140

Gln Asp His Gln Pro Lys Arg Leu Xaa Tyr Thr Ser Ser Ile Gly Arg
145                 150                 155                 160

Gly Xaa Gly Ile Pro Xaa Leu Ala Leu Phe Lys Asn Ser Pro Leu Xaa
                165                 170                 175






<210> 2478
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (14)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (40)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2478
Met Tyr Asn Ser Arg Gly Pro Thr Leu Ser Asn Tyr Val Xaa Lys Cys
  1               5                  10                  15

Ala Pro Arg Lys Ser Leu Lys Val Gln Pro Arg Phe Thr Trp Val Ile
             20                  25                  30

Ser Gly Gln Lys Asp Gln Ala Xaa Phe Xaa Xaa Ser Ser Tyr Ser Ser
         35                  40                  45

Val Leu Leu Ser Phe Ser Ile Leu Ser Val Ser Phe Gly Met Leu Met
     50                  55                  60

Gln Val Gly Asn Phe Thr Leu Pro Arg Ile Tyr Gly Leu Ile His Ala
 65                  70                  75                  80

Ser Val Ala Leu Thr Met Leu Ser Xaa Gln Xaa Leu Leu Xaa His Thr
                 85                  90                  95

Cys Ser Xaa His Leu Leu Gln Gly Glu Gly Thr 
            100                 105



<210> 2479
<211> 314
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (251)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2479
Met Ala Thr Ala Val Ser Arg Pro Cys Ala Gly Arg Ser Arg Asp Ile
  1               5                  10                  15

Leu Trp Arg Val Leu Gly Trp Arg Ile Xaa Ala Ser Ile Val Trp Ser
             20                  25                  30

Val Leu Phe Leu Pro Ile Cys Thr Thr Val Phe Ile Ile Phe Ser Xaa
         35                  40                  45

Ile Asp Leu Phe His Pro Ile Gln Trp Leu Ser Asp Ser Phe Ser Asp
     50                  55                  60

Leu Tyr Ser Ser Tyr Val Ile Phe Tyr Phe Leu Leu Leu Ser Val Val
 65                  70                  75                  80

Ile Ile Ile Ile Ser Ile Phe Asn Val Glu Phe Tyr Ala Val Val Pro
                 85                  90                  95

Ser Ile Pro Cys Ser Arg Leu Ala Leu Ile Gly Lys Ile Ile His Pro
            100                 105                 110

Gln Gln Leu Met His Ser Phe Ile His Ala Ala Met Gly Met Val Met
        115                 120                 125

Ala Trp Cys Ala Ala Val Ile Thr Gln Gly Gln Tyr Ser Phe Leu Val
    130                 135                 140

Val Pro Cys Thr Gly Thr Asn Ser Phe Gly Ser Pro Ala Ala Gln Thr
145                 150                 155                 160

Cys Leu Asn Glu Tyr His Leu Phe Phe Leu Leu Leu Glu His Leu Trp
                165                 170                 175

Ala Ile Ala Ile Ala Ser Cys Ile Leu Val Gln His Glu Leu Ser Pro
            180                 185                 190

Phe Pro Ile Ile Gln Gln Tyr Lys Phe Leu Arg Xaa Arg Arg Ser Leu
        195                 200                 205

Leu Leu Leu Val Lys His Ser Cys Val Glu Ser Leu Phe Leu Val Arg
    210                 215                 220

Asn Phe Cys Ile Leu Tyr Tyr Phe Leu Gly Tyr Ile Pro Lys Ala Trp
225                 230                 235                 240

Ile Ser Thr Ala Met Asn Leu His Ile Asp Xaa Gln Val His Arg Pro
                245                 250                 255

Leu Asp Thr Val Ser Gly Leu Leu Lys Ser Leu Val Thr Leu Pro Cys
            260                 265                 270

Pro Gly Trp Cys Gly Val Phe Leu Leu Thr Thr Trp Tyr Val Ser Trp
        275                 280                 285

Ile Leu Phe Lys Ile Tyr Ala Thr Glu Ala His Val Phe Ser Trp Phe
    290                 295                 300

Lys Pro Pro Phe Gly Lys Lys Gly Val Arg 
305                 310



<210> 2480
<211> 124
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (100)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2480
Met Asn Trp Gln His Ser Thr Met Tyr Leu Phe Phe Ala Val Xaa Gly
  1               5                  10                  15

Ile Val Asp Met Leu Thr Tyr Leu Val Ser His Val Pro Leu Gly Val
             20                  25                  30

Asp Arg Leu Val Met Ala Val Ala Val Phe Met Glu Gly Phe Leu Phe
         35                  40                  45

Tyr Tyr His Val His Asn Arg Pro Pro Leu Asp Gln His Ile His Ser
     50                  55                  60

Leu Leu Leu Tyr Ala Leu Phe Gly Gly Cys Val Ser Ile Ser Leu Glu
 65                  70                  75                  80

Val Ile Phe Arg Asp His Ile Val Leu Glu Leu Phe Arg Thr Ser Leu
                 85                  90                  95

Ile Ile Leu Xaa Gly Asn Leu Val Leu Ala Asp Trp Val Cys Ala Val
            100                 105                 110

Pro Thr Phe Trp Asn Thr Arg Met Gly Pro Glu Gly 
        115                 120



<210> 2481
<211> 217
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2481
Met Tyr Gln Thr Gln Val Ser Asp Ala Gly Leu Tyr Arg Cys Met Val
  1               5                  10                  15

Thr Ala Trp Ser Pro Val Arg Gly Ser Leu Trp Arg Glu Ala Ala Thr
             20                  25                  30

Ser Leu Ser Asn Pro Ile Glu Ile Asp Phe Gln Thr Ser Gly Pro Ile
         35                  40                  45

Phe Asn Ala Ser Val His Ser Asp Thr Pro Ser Val Ile Arg Gly Asp
     50                  55                  60

Leu Ile Lys Leu Phe Cys Ile Ile Thr Val Glu Gly Ala Ala Leu Asp
 65                  70                  75                  80

Pro Asp Asp Met Ala Phe Asp Val Ser Trp Phe Ala Val His Ser Phe
                 85                  90                  95

Gly Leu Asp Lys Ala Pro Val Leu Leu Ser Ser Leu Asp Arg Lys Gly
            100                 105                 110

Ile Val Thr Thr Ser Arg Arg Asp Trp Lys Ser Asp Leu Ser Leu Glu
        115                 120                 125

Arg Val Ser Val Leu Glu Phe Leu Leu Gln Val His Gly Ser Glu Asp
    130                 135                 140

Gln Asp Phe Gly Asn Tyr Tyr Cys Ser Val Thr Pro Trp Val Lys Ser
145                 150                 155                 160

Xaa Thr Gly Ser Trp Gln Lys Glu Ala Glu Ile His Ser Lys Pro Val
                165                 170                 175

Phe Ile Thr Val Lys Met Asp Val Leu Asn Ala Phe Lys Tyr Pro Leu
            180                 185                 190

Leu Ile Gly Val Gly Leu Ser Thr Val Ile Gly Leu Leu Ser Cys Leu
        195                 200                 205

Ile Gly Tyr Cys Ser Ser His Trp Cys 
    210                 215



<210> 2482
<211> 147
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2482
Met Glu Leu Gly Arg Asn Arg Pro Cys Ala Ser Ser Arg Gly Pro Ser
  1               5                  10                  15

Ser Phe Pro Pro Ser Leu His Gly Arg Pro Leu Glu Pro Pro Cys Cys
             20                  25                  30

Thr Glu Leu Trp Ala Pro Pro Ile Cys Asn Val Thr Leu Lys Phe Leu
         35                  40                  45

Val Leu Phe Leu Cys Cys Asn Val Asn Thr Gly Phe Leu Asp Phe Phe
     50                  55                  60

Phe Leu Met Gly Val Leu Gly Gly Thr Asp Gly Val Arg Glu Ala Pro
 65                  70                  75                  80

Pro Trp Leu Val Glu Gly Thr Gly Thr Cys Met Ala Ala Leu Ser Leu
                 85                  90                  95

Pro Pro Leu Pro Gly Cys Lys Pro Glu Val Cys Ala Ala Gly Arg Gly
            100                 105                 110

Cys Ser Gly Leu Gly Leu Gln Xaa Arg Cys Pro Gly Gln Gly Thr Leu
        115                 120                 125

Met His Arg Pro Asn Pro Gly Leu Gly Arg Thr Cys Pro Leu Thr Ala
    130                 135                 140

Ser Cys Leu 
145



<210> 2483
<211> 168
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (77)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (138)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2483
Met Val Pro Met His Leu Leu Gly Arg Leu Glu Lys Pro Leu Leu Leu
  1               5                  10                  15

Leu Cys Cys Ala Ser Phe Leu Leu Gly Leu Ala Leu Leu Gly Ile Lys
             20                  25                  30

Thr Asp Ile Thr Pro Val Ala Tyr Phe Phe Leu Thr Leu Gly Gly Phe
         35                  40                  45

Phe Leu Phe Ala Tyr Leu Leu Val Arg Phe Leu Glu Trp Gly Leu Arg
     50                  55                  60

Ser Gln Leu Gln Ser Met Gln Thr Xaa Ser Pro Gly Xaa Ser Gly Asn
 65                  70                  75                  80

Ala Arg Asp Asn Glu Ala Phe Glu Val Pro Val Tyr Glu Glu Ala Val
                 85                  90                  95

Val Gly Leu Glu Ser Gln Cys Arg Pro Lys Ser Trp Thr Asn His Pro
            100                 105                 110

Pro Thr Ala Thr Gly Gly Asp Thr Pro Ser Thr Leu Xaa Xaa Glu Gln
        115                 120                 125

Pro Ser Pro Phe Gln Lys Gly Ser Arg Xaa Lys Pro Lys Leu Gly Thr
    130                 135                 140

Glu Ala Glu Trp Ala Leu Xaa Gly Gly Pro Met Gly Pro Arg Lys Gly
145                 150                 155                 160

Xaa Pro Trp Glu Glu Leu Pro Asn 
                165



<210> 2484
<211> 317
<212> PRT
<213> Homo sapiens

<400> 2484
Met Gln Asp Glu Gln Pro Ser Asp Ser Phe Gln Gly Gln Ala Ala Gln
  1               5                  10                  15

Ser Gly Val Trp Asn Asp Asp Arg Leu Leu Gly Pro Ser Gln Asn Phe
             20                  25                  30

Glu Ala Glu Ser Ile Gln Asp Asn Ala His Met Ala Glu Gly Thr Gly
         35                  40                  45

Phe Tyr Pro Ser Glu Pro Met Leu Cys Ser Glu Ser Val Glu Gly Gln
     50                  55                  60

Val Pro His Ser Leu Glu Thr Leu Tyr Gln Ser Ala Asp Cys Ser Asp
 65                  70                  75                  80

Ala Asn Asp Ala Leu Ile Val Leu Ile His Leu Leu Met Leu Glu Ser
                 85                  90                  95

Gly Tyr Ile Pro Gln Gly Thr Glu Ala Lys Ala Leu Ser Met Pro Glu
            100                 105                 110

Lys Trp Lys Leu Ser Gly Val Tyr Lys Leu Gln Tyr Met His Pro Leu
        115                 120                 125

Cys Glu Gly Ser Ser Ala Thr Leu Thr Cys Val Pro Leu Gly Asn Leu
    130                 135                 140

Ile Val Val Asn Ala Thr Leu Lys Ile Asn Asn Glu Ile Arg Ser Val
145                 150                 155                 160

Lys Arg Leu Gln Leu Leu Pro Glu Ser Phe Ile Cys Lys Glu Lys Leu
                165                 170                 175

Gly Glu Asn Val Ala Asn Ile Tyr Lys Asp Leu Gln Lys Leu Ser Arg
            180                 185                 190

Leu Phe Lys Asp Gln Leu Val Tyr Pro Leu Leu Ala Phe Thr Arg Gln
        195                 200                 205

Ala Leu Asn Leu Pro Asp Val Phe Gly Leu Val Val Leu Pro Leu Glu
    210                 215                 220

Leu Lys Leu Arg Ile Phe Arg Leu Leu Asp Val Arg Ser Val Leu Ser
225                 230                 235                 240

Leu Ser Ala Val Cys Arg Asp Leu Phe Thr Ala Ser Asn Asp Pro Leu
                245                 250                 255

Leu Trp Arg Phe Leu Tyr Leu Arg Asp Phe Arg Asp Asn Thr Val Arg
            260                 265                 270

Val Gln Asp Thr Asp Trp Lys Glu Leu Tyr Arg Lys Arg His Ile Gln
        275                 280                 285

Arg Lys Glu Ser Pro Lys Gly Arg Val Cys Asp Ala Pro Ala Ile Val
    290                 295                 300

Asn Ser His His Ser Ile Leu Ser Gln Pro Leu Ala Pro 
305                 310                 315



<210> 2485
<211> 462
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2485
Met Arg Leu Arg Val Arg Leu Leu Lys Arg Thr Trp Pro Leu Glu Val
  1               5                  10                  15

Pro Glu Thr Glu Pro Thr Leu Gly His Leu Arg Ser His Leu Arg Gln
             20                  25                  30

Ser Leu Leu Cys Thr Trp Gly Tyr Ser Ser Asn Thr Arg Phe Thr Ile
         35                  40                  45

Thr Leu Asn Tyr Lys Asp Pro Leu Thr Gly Asp Glu Glu Thr Leu Ala
     50                  55                  60

Ser Tyr Gly Ile Val Ser Gly Asp Leu Ile Cys Leu Ile Leu Gln Asp
 65                  70                  75                  80

Asp Ile Pro Ala Pro Asn Ile Pro Ser Ser Thr Asp Ser Glu His Ser
                 85                  90                  95

Ser Leu Gln Asn Asn Glu Gln Pro Ser Leu Ala Thr Ser Ser Asn Gln
            100                 105                 110

Thr Ser Xaa Gln Asp Glu Gln Pro Ser Asp Ser Phe Gln Gly Gln Ala
        115                 120                 125

Ala Gln Ser Gly Val Trp Asn Asp Asp Ser Met Leu Gly Pro Ser Gln
    130                 135                 140

Asn Phe Glu Ala Glu Ser Ile Gln Asp Asn Ala His Met Ala Glu Gly
145                 150                 155                 160

Thr Gly Phe Tyr Pro Ser Glu Pro Met Leu Cys Ser Glu Ser Val Glu
                165                 170                 175

Gly Gln Val Pro His Ser Leu Glu Thr Leu Tyr Gln Ser Ala Asp Cys
            180                 185                 190

Ser Asp Ala Asn Asp Ala Leu Ile Val Leu Ile His Leu Leu Met Leu
        195                 200                 205

Glu Ser Gly Tyr Ile Pro Gln Gly Thr Glu Ala Lys Ala Leu Ser Met
    210                 215                 220

Pro Glu Lys Trp Lys Leu Ser Gly Val Tyr Lys Leu Gln Tyr Met His
225                 230                 235                 240

Pro Leu Cys Glu Gly Ser Ser Ala Thr Leu Thr Cys Val Pro Leu Gly
                245                 250                 255

Asn Leu Ile Val Val Asn Ala Leu Asn Leu Pro Asp Val Phe Gly Leu
            260                 265                 270

Val Val Leu Pro Leu Glu Leu Lys Leu Arg Ile Phe Arg Leu Leu Asp
        275                 280                 285

Val Arg Ser Val Leu Ser Leu Ser Ala Val Cys Arg Asp Leu Phe Thr
    290                 295                 300

Ala Ser Asn Asp Pro Leu Leu Trp Arg Phe Leu Tyr Leu Arg Asp Phe
305                 310                 315                 320

Arg Asp Asn Thr Val Arg Val Gln Asp Thr Asp Trp Lys Glu Leu Tyr
                325                 330                 335

Arg Lys Arg His Ile Gln Arg Lys Glu Ser Pro Lys Gly Arg Phe Val
            340                 345                 350

Met Leu Leu Pro Ser Ser Thr His Thr Ile Pro Phe Tyr Pro Asn Pro
        355                 360                 365

Leu His Pro Arg Pro Phe Pro Ser Ser Arg Leu Pro Pro Gly Ile Ile
    370                 375                 380

Gly Gly Glu Tyr Asp Gln Arg Pro Thr Leu Pro Tyr Val Gly Asp Pro
385                 390                 395                 400

Ile Ser Ser Leu Ile Pro Gly Pro Gly Glu Thr Pro Ser Gln Phe Pro
                405                 410                 415

Pro Leu Arg Pro Arg Phe Asp Pro Val Gly Pro Leu Pro Gly Pro Asn
            420                 425                 430

Pro Ile Leu Pro Gly Arg Gly Gly Pro Asn Asp Arg Phe Pro Phe Arg
        435                 440                 445

Pro Ser Arg Gly Arg Pro Thr Asp Gly Arg Leu Ser Phe Met 
    450                 455                 460



<210> 2486
<211> 113
<212> PRT
<213> Homo sapiens

<400> 2486
Met Phe Val Ala Val Phe Leu Trp Leu Val Thr Ile Val Leu Phe Asn
  1               5                  10                  15

Leu Tyr Leu Phe Gln Leu His Met Lys Leu Tyr Met Val Pro Trp Pro
             20                  25                  30

Leu Val Leu Met Ile Phe Asn Ile Ser Ala Thr Val Leu Tyr Ile Thr
         35                  40                  45

Ala Phe Ile Ala Cys Ser Ala Ala Val Asp Leu Thr Ser Leu Arg Gly
     50                  55                  60

Thr Arg Pro Tyr Asn Gln Arg Ala Ala Ala Ser Phe Phe Ala Cys Leu
 65                  70                  75                  80

Val Met Ile Ala Tyr Gly Val Ser Ala Phe Phe Ser Tyr Gln Ala Trp
                 85                  90                  95

Arg Gly Val Gly Ser Asn Ala Ala Thr Ser Gln Met Ala Gly Gly Tyr
            100                 105                 110

Ala 




<210> 2487
<211> 338
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (318)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2487
Met Arg Thr Arg Lys Leu Lys Leu Ala Val Leu Asn Ser Phe Phe Asn
  1               5                  10                  15

Leu Glu Cys Cys Val Ser Gly Thr His Ser Met Asp Leu Val Ala Leu
             20                  25                  30

Ala Pro Phe Gly Glu Tyr Thr Val Leu Pro Gly Leu Asp Cys Thr Phe
         35                  40                  45

Ser Lys Gly Tyr Gln Gly Leu Thr Asn Cys Met Met Ala Ala Leu Pro
     50                  55                  60

Glu Asp Thr Val Val Phe Glu Lys Pro Val Lys Thr Ile His Trp Asn
 65                  70                  75                  80

Gly Ser Phe Gln Glu Ala Ala Phe Pro Gly Glu Thr Phe Pro Val Ser
                 85                  90                  95

Val Glu Cys Glu Asp Gly Asp Arg Phe Pro Ala His His Val Ile Val
            100                 105                 110

Thr Val Pro Leu Gly Phe Leu Arg Glu His Leu Asp Thr Phe Phe Asp
        115                 120                 125

Pro Pro Leu Pro Ala Glu Lys Ala Glu Ala Ile Arg Lys Ile Gly Phe
    130                 135                 140

Gly Thr Asn Asn Lys Ile Phe Leu Glu Phe Glu Glu Pro Phe Trp Glu
145                 150                 155                 160

Pro Asp Cys Gln Leu Ile Gln Leu Val Trp Glu Asp Thr Ser Pro Leu
                165                 170                 175

Glu Asp Ala Ala Pro Glu Leu Gln Asp Ala Trp Phe Arg Lys Leu Ile
            180                 185                 190

Gly Phe Val Val Leu Pro Ala Phe Ala Ser Val His Val Leu Cys Gly
        195                 200                 205

Phe Ile Ala Gly Leu Glu Ser Glu Phe Met Glu Thr Leu Ser Asp Glu
    210                 215                 220

Glu Val Leu Leu Cys Leu Thr Gln Val Leu Arg Arg Val Thr Gly Asn
225                 230                 235                 240

Pro Arg Leu Pro Ala Pro Lys Ser Val Leu Arg Ser Arg Trp His Ser
                245                 250                 255

Ala Pro Tyr Thr Arg Gly Ser Tyr Ser Tyr Val Ala Val Gly Ser Thr
            260                 265                 270

Gly Gly Asp Leu Asp Leu Leu Ala Gln Pro Leu Pro Ala Asp Gly Ala
        275                 280                 285

Gly Ala Gln Leu Gln Ile Leu Phe Ala Gly Glu Ala Thr His Arg Thr
    290                 295                 300

Phe Tyr Ser Thr Thr His Gly Ala Leu Leu Ser Gly Trp Xaa Glu Ala
305                 310                 315                 320

Asp Arg Leu Leu Ser Leu Trp Ala Pro Gln Val Gln Gln Pro Arg Pro
                325                 330                 335

Arg Leu 




<210> 2488
<211> 195
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (181)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2488
Met Leu Phe Phe Leu Val Ser Val Ile Tyr Lys Lys Phe Gln Leu Gly
  1               5                  10                  15

Cys Ala Ile Gly His Asn Glu Thr Ala Met Glu Ser Glu Ala Leu Val
             20                  25                  30

Gly Leu Pro Ser Gln Gly Leu Asn Ser Ser Cys Glu Ala Gln Met Phe
         35                  40                  45

Thr Val Asp Ser Gln Met Ser Tyr Thr Val Pro Ile Met Ala Phe Ala
     50                  55                  60

Phe Val Cys His Pro Glu Val Leu Pro Ile Tyr Thr Glu Leu Cys Arg
 65                  70                  75                  80

Pro Ser Lys Arg Arg Met Gln Ala Val Ala Asn Val Ser Ile Gly Ala
                 85                  90                  95

Met Phe Cys Met Tyr Gly Leu Thr Ala Thr Phe Gly Tyr Leu Thr Phe
            100                 105                 110

Tyr Ser Ser Val Lys Ala Glu Met Leu His Met Tyr Ser Gln Lys Asp
        115                 120                 125

Pro Leu Ile Leu Cys Val Arg Leu Ala Val Leu Leu Ala Val Thr Leu
    130                 135                 140

Thr Val Pro Val Val Leu Phe Pro Ile Arg Arg Ala Leu Gln Gln Leu
145                 150                 155                 160

Leu Phe Pro Gly Lys Ala Phe Ser Trp Pro Arg His Val Ala Ile Ala
                165                 170                 175

Leu Ile Leu Leu Xaa Leu Val Asn Val Leu Ala Ser Xaa Xaa Gln Pro
            180                 185                 190

Xaa Gly Ile 
        195



<210> 2489
<211> 208
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (207)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2489
Met Asp Ile Leu Asp Val Leu Thr Leu Ala Ala Gln Glu Leu Ser Arg
  1               5                  10                  15

Pro Gly Cys Leu Gly Arg Thr Pro Gln Pro Gly Ser Pro Ser Pro Asn
             20                  25                  30

Thr Pro Cys Leu Pro Glu Ala Ala Val Ser Gln Pro Gly Ser Ala Val
         35                  40                  45

Ala Ser Asp Trp Arg Val Val Val Glu Glu Arg Ile Arg Ser Lys Thr
     50                  55                  60

Gln Arg Leu Ser Lys Gly Gly Pro Arg Gln Gly Pro Ala Gly Ser Pro
 65                  70                  75                  80

Ser Arg Phe Asn Ser Val Ala Gly His Phe Phe Phe Pro Leu Leu Gln
                 85                  90                  95

Arg Phe Asp Arg Pro Leu Val Thr Phe Asp Leu Leu Gly Glu Asp Gln
            100                 105                 110

Leu Val Leu Gly Arg Leu Ala His Thr Leu Gly Ala Leu Met Cys Leu
        115                 120                 125

Ala Val Asn Thr Thr Val Ala Val Ala Met Gly Lys Ala Leu Leu Glu
    130                 135                 140

Phe Val Trp Ala Leu Arg Phe His Ile Asp Ala Tyr Val Arg Gln Gly
145                 150                 155                 160

Leu Leu Ser Ala Val Ser Ser Val Leu Leu Ser Leu Pro Ala Ala Arg
                165                 170                 175

Leu Leu Glu Asp Leu Met Asp Glu Leu Leu Glu Ala Arg Ser Trp Leu
            180                 185                 190

Ala Asp Val Ala Glu Lys Asp Pro Asp Glu Asp Xaa Arg Arg Xaa His
        195                 200                 205






<210> 2490
<211> 133
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (64)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (91)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2490
Met Arg Thr Ala Gly Arg Gly Ser Cys Arg Thr His Trp Ala Phe Pro
  1               5                  10                  15

Thr Ala Cys Ser Ser Cys Thr Val Cys Gly Cys Pro Leu Ser Arg Thr
             20                  25                  30

Ala Pro Pro Ser Cys Trp Pro Cys Trp Pro Leu Met Ser Ser Leu Ser
         35                  40                  45

Ser Ser Pro Pro Ser Ser Pro Lys Pro Gly Glu Ser Ile Met Ala Xaa
     50                  55                  60

Val Ala Leu Gly Pro Ala Glu Ser Ser Ser His Glu Arg Leu Pro Met
 65                  70                  75                  80

Val Leu Lys Val Pro Arg Leu Arg Val Ser Xaa Leu Thr Leu Cys Ser
                 85                  90                  95

Gln Pro Phe Ser Ile Leu Gly Phe Gly Asp Ile Val Val Pro Gly Phe
            100                 105                 110

Leu Val Ala Tyr Cys Cys Arg Phe Asp Val Gln Val Cys Ser Arg Gln
        115                 120                 125

Ile Tyr Phe Val Ala 
    130



<210> 2491
<211> 278
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (235)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2491
Met Thr His Ala Phe Phe Lys Ala Leu Leu Phe Leu Ala Ser Gly Ser
  1               5                  10                  15

Val Ile Leu Ala Cys His His Glu Gln Asn Ile Phe Lys Met Gly Gly
             20                  25                  30

Leu Arg Lys Ser Ile Pro Leu Val Tyr Leu Cys Phe Leu Val Gly Gly
         35                  40                  45

Ala Ala Leu Ser Ala Leu Pro Leu Val Thr Ala Gly Phe Phe Ser Lys
     50                  55                  60

Asp Glu Ile Leu Ala Gly Ala Met Ala Asn Gly His Ile Asn Leu Met
 65                  70                  75                  80

Val Ala Gly Leu Xaa Gly Ala Phe Met Thr Ser Leu Tyr Thr Phe Arg
                 85                  90                  95

Met Ile Phe Ile Val Phe His Gly Lys Xaa Gln Ile His Ala His Ala
            100                 105                 110

Val Lys Gly Val Thr His Ser Leu Pro Leu Ile Val Leu Leu Ile Leu
        115                 120                 125

Ser Thr Phe Val Gly Ala Leu Ile Val Pro Pro Leu Gln Gly Val Leu
    130                 135                 140

Pro Gln Thr Thr Glu Leu Ala His Gly Ser Met Xaa Thr Leu Glu Ile
145                 150                 155                 160

Thr Ser Gly Val Val Ala Val Val Gly Ile Leu Leu Ala Ala Trp Leu
                165                 170                 175

Trp Leu Gly Lys Arg Thr Leu Val Thr Ser Ile Ala Asn Ser Ala Pro
            180                 185                 190

Gly Arg Leu Leu Gly Thr Trp Trp Tyr Asn Ala Trp Gly Phe Asp Trp
        195                 200                 205

Leu Tyr Asp Lys Val Phe Val Lys Pro Phe Leu Gly Ile Ala Trp Leu
    210                 215                 220

Leu Lys Arg Asp Pro Leu Asn Ser Met Met Xaa Ile Pro Ala Val Leu
225                 230                 235                 240

Ser Arg Phe Ala Gly Lys Gly Leu Leu Leu Ser Glu Asn Gly Tyr Leu
                245                 250                 255

Arg Trp Tyr Val Ala Ser Met Ser Ile Gly Ala Val Val Val Leu Ala
            260                 265                 270

Leu Leu Met Val Xaa Arg 
        275



<210> 2492
<211> 209
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2492
Met Asp Thr Ser Ala Val Phe Val Thr Thr Cys Leu Ile Ala Ala Phe
  1               5                  10                  15

Gly Ser Ile Met Met Gly Leu Phe Ala Asn Leu Pro Val Ala Leu Ala
             20                  25                  30

Pro Ala Met Gly Leu Asn Ala Phe Phe Ala Phe Val Val Val Gln Ala
         35                  40                  45

Met Gly Leu Pro Trp Gln Val Gly Met Gly Ala Ile Phe Trp Gly Ala
     50                  55                  60

Ile Gly Leu Leu Leu Leu Thr Ile Phe Arg Val Arg Tyr Trp Met Ile
 65                  70                  75                  80

Ala Asn Ile Pro Val Ser Leu Arg Val Gly Ile Thr Ser Gly Ile Gly
                 85                  90                  95

Leu Phe Ile Gly Met Met Gly Leu Lys Asn Ala Gly Val Ile Val Ala
            100                 105                 110

Asn Pro Glu Thr Leu Val Ser Ile Gly Asn Leu Thr Ser His Ser Val
        115                 120                 125

Leu Leu Gly Ile Leu Gly Phe Phe Ile Ile Ala Ile Leu Ala Ser Arg
    130                 135                 140

Asn Ile His Ala Ala Val Leu Val Ser Ile Val Val Thr Thr Leu Leu
145                 150                 155                 160

Gly Trp Met Leu Gly Asp Val His Tyr Asn Gly Ile Val Ser Ala Pro
                165                 170                 175

Pro Ser Val Met Thr Val Val Gly His Val Asp Leu Ala Gly Ser Phe
            180                 185                 190

Asn Leu Gly Leu Ala Glu Gly Pro Gly Ser Ile Pro Val Gly Thr Pro
        195                 200                 205

Xaa 




<210> 2493
<211> 251
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (191)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (217)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (250)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2493
Met Asp Asn Ser Trp Arg Leu Gly Pro Ala Ile Gly Leu Ser Ala Gly
  1               5                  10                  15

Gln Ser Gln Leu Leu Val Ser Leu Leu Leu Leu Leu Thr Arg Val Gln
             20                  25                  30

Pro Gly Thr Asp Val Ala Ala Pro Glu His Ile Ser Tyr Val Pro Gln
         35                  40                  45

Leu Ser Asn Asp Thr Leu Ala Gly Arg Leu Thr Leu Ser Thr Phe Thr
     50                  55                  60

Leu Glu Gln Pro Leu Gly Gln Phe Ser Ser His Asn Ile Ser Asp Leu
 65                  70                  75                  80

Asp Thr Ile Trp Leu Val Val Ala Leu Ser Asn Ala Thr Gln Ser Phe
                 85                  90                  95

Thr Ala Pro Arg Thr Asn Gln Asp Ile Pro Ala Pro Ala Asn Phe Ser
            100                 105                 110

Gln Arg Gly Tyr Tyr Leu Thr Leu Arg Ala Asn Arg Val Leu Tyr Gln
        115                 120                 125

Thr Arg Gly Gln Leu His Val Leu Arg Val Gly Asn Asp Thr His Cys
    130                 135                 140

Gln Pro Thr Lys Ile Gly Cys Asn His Pro Leu Pro Gly Pro Gly Pro
145                 150                 155                 160

Tyr Arg Val Lys Phe Leu Val Met Asn Asp Glu Gly Pro Val Ala Glu
                165                 170                 175

Thr Lys Trp Ser Ser Asp Thr Arg Leu Gln Gln Ala Gln Ala Xaa Arg
            180                 185                 190

Ala Val Pro Gly Pro Gln Ser Pro Gly Thr Trp Phe Ile Ile Ala Ile
        195                 200                 205

Leu Ser Ile Leu Leu Ala Val Xaa Xaa Arg Ser Leu Ala Val Leu Ile
    210                 215                 220

Tyr Thr Gly Leu Leu Leu Pro Lys Phe Phe Trp Gly Phe Gly Met Asp
225                 230                 235                 240

Arg Arg Gln Gln Gln Lys His Val Asp Xaa Trp 
                245                 250



<210> 2494
<211> 493
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (477)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (479)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (482)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (488)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2494
Met Pro Thr Leu Glu Gly Trp Val Val Leu Trp Gln Gln Lys Ala Ala
  1               5                  10                  15

Glu Ala Leu Thr Pro Thr Gln Xaa Ala Gln Gly Glu Thr Glu Pro Thr
             20                  25                  30

Glu Gln Ala Pro Asp Ala Leu Glu Gln Ala Ala Asp Thr Ser Arg Arg
         35                  40                  45

Asn Ala Glu Thr Pro Glu Ala Thr Thr Gln Gln Glu Thr Asp Thr Asp
     50                  55                  60

Leu Pro Glu Ala Pro Pro Pro Pro Leu Glu Pro Ala Val Ile Ala Arg
 65                  70                  75                  80

Pro Gly Cys Val Asn Leu Ser Leu His Gly Ile Val Glu Asp Arg Arg
                 85                  90                  95

Pro Lys Glu Arg Ile Ser Phe Glu Val Met Val Leu Ala Glu Leu Phe
            100                 105                 110

Leu Glu Met Leu Gln Arg Asp Phe Gly Tyr Arg Val Tyr Lys Met Leu
        115                 120                 125

Leu Ser Leu Pro Glu Lys Val Val Ser Pro Pro Glu Pro Glu Lys Glu
    130                 135                 140

Glu Ala Ala Lys Glu Glu Ala Thr Lys Glu Glu Glu Ala Ile Lys Glu
145                 150                 155                 160

Glu Val Val Lys Glu Pro Lys Asp Glu Ala Gln Asn Glu Gly Pro Ala
                165                 170                 175

Thr Glu Ser Glu Ala Pro Leu Lys Glu Asp Gly Leu Leu Pro Lys Pro
            180                 185                 190

Leu Ser Ser Gly Gly Glu Glu Glu Glu Lys Pro Arg Gly Glu Ala Ser
        195                 200                 205

Glu Asp Leu Cys Glu Met Ala Leu Asp Pro Glu Leu Leu Leu Leu Arg
    210                 215                 220

Asp Asp Gly Glu Glu Glu Phe Ala Gly Ala Lys Leu Glu Asp Ser Glu
225                 230                 235                 240

Val Arg Ser Val Ala Ser Asn Gln Ser Glu Met Glu Phe Ser Ser Leu
                245                 250                 255

Gln Asp Met Pro Lys Glu Leu Asp Pro Ser Ala Val Leu Pro Leu Asp
            260                 265                 270

Cys Leu Leu Ala Phe Val Phe Phe Asp Ala Asn Trp Cys Gly Tyr Leu
        275                 280                 285

His Arg Arg Asp Leu Glu Arg Ile Leu Leu Thr Leu Gly Ile Arg Leu
    290                 295                 300

Ser Ala Glu Gln Ala Lys Gln Leu Val Ser Arg Val Val Thr Gln Asn
305                 310                 315                 320

Ile Cys Gln Tyr Arg Ser Leu Gln Tyr Ser Arg Gln Glu Gly Leu Asp
                325                 330                 335

Gly Gly Leu Pro Glu Glu Val Leu Phe Gly Asn Leu Asp Leu Leu Pro
            340                 345                 350

Pro Pro Gly Lys Ser Thr Lys Pro Gly Ala Ala Pro Thr Glu His Lys
        355                 360                 365

Ala Leu Val Ser His Asn Gly Ser Leu Ile Asn Val Gly Ser Leu Leu
    370                 375                 380

Gln Arg Ala Glu Gln Gln Asp Ser Gly Arg Leu Tyr Leu Glu Asn Lys
385                 390                 395                 400

Ile His Thr Leu Glu Leu Lys Leu Glu Glu Ser His Asn Arg Phe Ser
                405                 410                 415

Ala Thr Glu Val Thr Asn Lys Thr Leu Ala Ala Glu Met Gln Glu Leu
            420                 425                 430

Arg Val Arg Leu Ala Glu Ala Glu Glu Thr Ala Arg Thr Ala Glu Arg
        435                 440                 445

Gln Lys Ser Gln Leu Gln Arg Leu Leu Gln Glu Leu Arg Arg Arg Leu
    450                 455                 460

Thr Pro Leu Gln Leu Glu Ile Gln Arg Val Val Glu Xaa Val Xaa Trp
465                 470                 475                 480

Val Xaa Arg Arg Gln His Asn Xaa Leu Thr Asn Ala Leu 
                485                 490



<210> 2495
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2495
Met Ser Leu Val Ala Tyr Val Ile Asn Ser Leu Val Asn Ile Cys Leu
  1               5                  10                  15

Ile Gly Thr Gln Asn Leu Phe Ser Leu Val Leu Ala Leu Trp Asp Ala
             20                  25                  30

Val Thr Gly Pro Leu Trp Arg Met Thr Asp Val Val Ala Ala Phe Leu
         35                  40                  45

Ala His Ile Ser Ser Ser Ala Val Ala Met Ala Ile Leu Leu Trp Thr
     50                  55                  60

Pro Cys Gln Leu Ala Leu Glu Leu Leu Ala Ser Ala Ala Arg Leu Leu
 65                  70                  75                  80

Ala Ser Phe Val Leu Val Asn Leu Thr Gly Leu Val Leu Leu Ala Cys
                 85                  90                  95

Val Leu Ala Val Xaa Val Leu Xaa Xaa Ile Xaa 
            100                 105



<210> 2496
<211> 130
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (129)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2496
Met Ala Ala Phe Leu Ala His Ile Ser Ser Ser Ala Val Ala Met Ala
  1               5                  10                  15

Ile Leu Leu Trp Thr Pro Cys Gln Leu Ala Leu Glu Leu Leu Ala Ser
             20                  25                  30

Xaa Ala Arg Leu Leu Ala Ser Phe Val Leu Val Asn Leu Thr Gly Leu
         35                  40                  45

Val Leu Leu Ala Cys Val Leu Ala Val Thr Val Thr Val Leu His Pro
     50                  55                  60

Asp Phe Thr Leu Arg Leu Ala Thr Gln Ala Leu Ser Gln Leu His Ala
 65                  70                  75                  80

Arg Pro Ser Tyr His Arg Leu Arg Glu Asp Val Met Arg Leu Ser Arg
                 85                  90                  95

Leu Ala Leu Gly Ser Glu Ala Trp Arg Arg Val Trp Ser Arg Ile Cys
            100                 105                 110

Ser Trp Arg Xaa Gly Gln Thr Gly Glu Gly His Trp Ser Ser Pro Gly
        115                 120                 125

Xaa Leu 
    130



<210> 2497
<211> 240
<212> PRT
<213> Homo sapiens

<400> 2497
Met Gln Thr Thr Tyr Val Leu Gln Ser Leu His Leu Arg Ile Pro Glu
  1               5                  10                  15

Ile Ser Asn Ile Thr Thr Thr Pro His Thr Leu Pro Ala Ala Trp Leu
             20                  25                  30

Thr Met Phe Asp Ala Val Leu Ile Leu Leu Leu Ile Pro Leu Lys Asp
         35                  40                  45

Lys Leu Val Asp Pro Ile Leu Arg Arg His Gly Leu Leu Pro Ser Ser
     50                  55                  60

Leu Lys Arg Ile Ala Val Gly Met Phe Phe Val Met Cys Ser Ala Phe
 65                  70                  75                  80

Ala Ala Gly Ile Leu Glu Ser Lys Arg Leu Asn Leu Val Lys Glu Lys
                 85                  90                  95

Thr Ile Asn Gln Thr Ile Gly Asn Val Val Tyr His Ala Ala Asp Leu
            100                 105                 110

Ser Leu Trp Trp Gln Val Pro Gln Tyr Leu Leu Ile Gly Ile Ser Glu
        115                 120                 125

Ile Phe Ala Ser Ile Ala Gly Leu Glu Phe Ala Tyr Ser Ala Ala Pro
    130                 135                 140

Lys Ser Met Gln Ser Ala Ile Met Gly Leu Phe Phe Phe Phe Ser Gly
145                 150                 155                 160

Val Gly Ser Phe Val Gly Ser Gly Leu Leu Ala Leu Val Ser Ile Lys
                165                 170                 175

Ala Ile Gly Trp Met Ser Ser His Thr Asp Phe Gly Asn Ile Asn Gly
            180                 185                 190

Cys Tyr Leu Asn Tyr Tyr Phe Phe Leu Leu Ala Ala Ile Gln Gly Ala
        195                 200                 205

Thr Leu Leu Leu Phe Leu Ile Ile Ser Val Lys Tyr Asp His His Arg
    210                 215                 220

Asp His Gln Arg Ser Arg Ala Asn Gly Val Pro Thr Ser Arg Arg Ala
225                 230                 235                 240






<210> 2498
<211> 238
<212> PRT
<213> Homo sapiens

<400> 2498
Met Ala Leu Val Pro Cys Gln Val Leu Arg Met Ala Ile Leu Leu Ser
  1               5                  10                  15

Tyr Cys Ser Ile Leu Cys Asn Tyr Lys Ala Ile Glu Met Pro Ser His
             20                  25                  30

Gln Thr Tyr Gly Gly Ser Trp Lys Phe Leu Thr Phe Ile Asp Leu Val
         35                  40                  45

Ile Gln Ala Val Phe Phe Gly Ile Cys Val Leu Thr Asp Leu Ser Ser
     50                  55                  60

Leu Leu Thr Arg Gly Ser Gly Asn Gln Glu Gln Glu Arg Gln Leu Lys
 65                  70                  75                  80

Lys Leu Ile Ser Leu Arg Asp Trp Met Leu Ala Val Leu Ala Phe Pro
                 85                  90                  95

Val Gly Val Phe Val Val Ala Val Phe Trp Ile Ile Tyr Ala Tyr Asp
            100                 105                 110

Arg Glu Met Ile Tyr Pro Lys Leu Leu Asp Asn Phe Ile Pro Gly Trp
        115                 120                 125

Leu Asn His Gly Met His Thr Thr Val Leu Pro Phe Ile Leu Ile Glu
    130                 135                 140

Met Arg Thr Ser His His Gln Tyr Pro Ser Arg Ser Ser Gly Leu Thr
145                 150                 155                 160

Ala Ile Cys Thr Phe Ser Val Gly Tyr Ile Leu Trp Val Cys Trp Val
                165                 170                 175

His His Val Thr Gly Met Trp Val Tyr Pro Phe Leu Glu His Ile Gly
            180                 185                 190

Pro Gly Ala Arg Ile Ile Phe Phe Gly Ser Thr Thr Ile Leu Met Asn
        195                 200                 205

Phe Leu Tyr Leu Leu Gly Glu Val Leu Asn Asn Tyr Ile Trp Asp Thr
    210                 215                 220

Gln Lys Ser Met Glu Glu Glu Lys Glu Lys Pro Lys Leu Glu 
225                 230                 235



<210> 2499
<211> 140
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2499
Met Lys Leu Gly Asn Thr Gly Ala Met Arg Arg Cys Val Lys Leu Thr
  1               5                  10                  15

Val Ala Leu Glu Thr Ala Glu Cys Glu Phe Pro Pro His Leu Asp Val
             20                  25                  30

Tyr Ile Glu Asp Pro His Leu Pro Pro Ser Leu Gly Leu Leu Pro Gly
         35                  40                  45

Ala Arg Val His Phe Ser Gln Leu Glu Lys Arg Val Ser Arg Ser His
     50                  55                  60

Asn Val Tyr Cys Cys Phe Arg Ser Ser Thr Tyr Val Gln Val Leu Ser
 65                  70                  75                  80

Phe Pro Pro Glu Thr Thr Ile Ser Xaa Pro Leu Pro His Ile Tyr Leu
                 85                  90                  95

Ala Glu Leu Leu Gln Gly Gly Gln Ser Pro Phe Gln Ala Thr Ala Ser
            100                 105                 110

Cys Ile Ser Leu Cys Leu Gln Pro Ser Ala Leu Leu Gly Val Cys Leu
        115                 120                 125

Leu Tyr Gln His Leu Pro Ala Val Phe Ser Gln Gly 
    130                 135                 140



<210> 2500
<211> 287
<212> PRT
<213> Homo sapiens

<400> 2500
Met Glu Phe Asn Pro Ser Asp His Pro Arg Ala Ser Thr Ile Phe Leu
  1               5                  10                  15

Ser Lys Ser Gln Thr Asp Val Arg Glu Lys Arg Lys Ser Leu Phe Ile
             20                  25                  30

Asn His His Pro Pro Gly Gln Ile Ala Arg Lys Tyr Ser Ser Cys Ser
         35                  40                  45

Thr Ile Phe Leu Asp Asp Ser Thr Val Ser Gln Pro Asn Leu Lys Tyr
     50                  55                  60

Thr Ile Lys Cys Val Ala Leu Ala Ile Tyr Tyr His Ile Lys Asn Arg
 65                  70                  75                  80

Asp Pro Asp Gly Arg Met Leu Leu Asp Ile Phe Asp Glu Asn Leu His
                 85                  90                  95

Pro Leu Ser Lys Ser Glu Val Pro Pro Asp Tyr Asp Lys His Asn Pro
            100                 105                 110

Glu Gln Lys Gln Ile Tyr Arg Phe Val Arg Thr Leu Phe Ser Ala Ala
        115                 120                 125

Gln Leu Thr Ala Glu Cys Ala Ile Val Thr Leu Val Tyr Leu Glu Arg
    130                 135                 140

Leu Leu Thr Tyr Ala Glu Ile Asp Ile Cys Pro Ala Asn Trp Lys Arg
145                 150                 155                 160

Ile Val Leu Gly Ala Ile Leu Leu Ala Ser Lys Val Trp Asp Asp Gln
                165                 170                 175

Ala Val Trp Asn Val Asp Tyr Cys Gln Ile Leu Lys Asp Ile Thr Val
            180                 185                 190

Glu Asp Met Asn Glu Leu Glu Arg Gln Phe Leu Glu Leu Leu Gln Phe
        195                 200                 205

Asn Ile Asn Val Pro Ser Ser Val Tyr Ala Lys Tyr Tyr Phe Asp Leu
    210                 215                 220

Arg Ser Leu Ala Glu Ala Asn Asn Leu Ser Phe Pro Leu Glu Pro Leu
225                 230                 235                 240

Ser Arg Glu Arg Ala His Lys Leu Glu Ala Ile Ser Arg Leu Cys Glu
                245                 250                 255

Asp Lys Tyr Lys Asp Leu Arg Arg Ser Ala Arg Lys Arg Ser Ala Ser
            260                 265                 270

Ala Asp Asn Leu Thr Leu Pro Arg Trp Ser Pro Ala Ile Ile Ser 
        275                 280                 285



<210> 2501
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (122)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2501
Met Phe Val Glu Thr Leu Trp Lys Val Trp Thr Glu Leu Leu Asp Val
  1               5                  10                  15

Leu Gly Leu Asp Val Ser Asn Leu Ser Gln Tyr Phe Ser Pro Ala Ser
             20                  25                  30

Val Ser Ser Ser Pro Ala Arg Ala Leu Leu Leu Val Gly Val Val Leu
         35                  40                  45

Leu Ala Tyr Trp Phe Leu Ser Leu Thr Leu Gly Phe Thr Phe Ser Val
     50                  55                  60

Leu His Val Val Phe Gly Arg Phe Phe Trp Ile Val Arg Val Val Leu
 65                  70                  75                  80

Phe Ser Met Ser Cys Val Tyr Ile Leu His Lys Tyr Glu Gly Glu Pro
                 85                  90                  95

Glu Asn Ala Val Leu Pro Leu Cys Phe Val Val Ala Val Tyr Phe Met
            100                 105                 110

Xaa Arg Ala His Gly Leu Leu Leu Ala Xaa Ser Pro Ser Gly Pro Ser
        115                 120                 125

Asn Pro Ser Asn Pro Ser Val Glu Glu Lys Leu Glu His Leu Glu Lys
    130                 135                 140

Gln Val Arg Leu Leu Asn Ile Arg Xaa Asn Arg Val Leu Glu Ser Leu
145                 150                 155                 160

Asp Arg Ser Lys Asp Lys 
                165



<210> 2502
<211> 320
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2502
Met Thr Leu Trp Asn Gly Val Leu Pro Phe Tyr Pro Gln Pro Arg His
  1               5                  10                  15

Ala Ala Gly Phe Ser Val Pro Leu Leu Ile Val Ile Leu Val Phe Leu
             20                  25                  30

Ala Leu Ala Ala Ser Phe Leu Leu Ile Leu Pro Gly Ile Arg Gly His
         35                  40                  45

Ser Arg Trp Phe Trp Leu Val Arg Val Leu Leu Ser Leu Phe Ile Gly
     50                  55                  60

Ala Glu Ile Val Ala Val His Phe Ser Ala Glu Trp Phe Val Gly Thr
 65                  70                  75                  80

Val Asn Thr Asn Thr Ser Tyr Lys Ala Phe Ser Ala Ala Arg Val Thr
                 85                  90                  95

Ala Arg Val Gly Leu Leu Val Gly Leu Xaa Gly Ile Asn Ile Thr Leu
            100                 105                 110

Thr Gly Thr Pro Val His Gln Leu Asn Glu Thr Ile Asp Tyr Asn Glu
        115                 120                 125

Gln Phe Thr Trp Arg Leu Lys Glu Asn Tyr Ala Ala Glu Tyr Ala Asn
    130                 135                 140

Ala Leu Glu Lys Gly Leu Pro Asp Pro Val Leu Tyr Leu Ala Glu Lys
145                 150                 155                 160

Phe Thr Pro Ser Ser Pro Cys Gly Leu Tyr His Gln Tyr His Leu Ala
                165                 170                 175

Gly His Tyr Ala Ser Ala Thr Leu Trp Val Ala Phe Cys Phe Trp Leu
            180                 185                 190

Leu Ser Asn Val Leu Leu Ser Thr Pro Ala Pro Leu Tyr Gly Gly Leu
        195                 200                 205

Ala Leu Leu Thr Thr Gly Ala Phe Ala Leu Phe Gly Val Phe Ala Leu
    210                 215                 220

Ala Ser Ile Ser Ser Val Pro Leu Cys Pro Leu Arg Leu Gly Ser Ser
225                 230                 235                 240

Ala Leu Thr Thr Gln Tyr Gly Ala Ala Phe Trp Val Thr Leu Ala Thr
                245                 250                 255

Gly Val Leu Cys Leu Phe Leu Gly Gly Ala Val Val Ser Leu Gln Tyr
            260                 265                 270

Val Arg Pro Ser Ala Leu Arg Thr Leu Leu Asp Gln Ser Ala Lys Asp
        275                 280                 285

Cys Ser Gln Glu Arg Gly Gly Ser Pro Leu Ile Leu Gly Asp Pro Leu
    290                 295                 300

His Lys Gln Ala Ala Leu Pro Asp Leu Lys Cys Ile Thr Thr Asn Leu
305                 310                 315                 320






<210> 2503
<211> 330
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2503
Met Val Met Tyr Ala Arg Lys Gln Gln Arg Leu Ser Asp Gly Cys His
  1               5                  10                  15

Asp Arg Arg Gly Asp Ser Gln Pro Tyr Gln Gly Gly Asp Val Leu Gln
             20                  25                  30

Ala Leu Lys Tyr Ser Ser Lys Ser His Pro Ser Ser Gly Asp His Arg
         35                  40                  45

His Glu Lys Met Arg Asp Ala Gly Asp Pro Ser Pro Pro Asn Lys Met
     50                  55                  60

Leu Arg Arg Ser Asp Ser Pro Glu Asn Lys Tyr Ser Asp Ser Thr Gly
 65                  70                  75                  80

His Ser Lys Ala Lys Asn Val His Thr His Arg Val Arg Glu Arg Asp
                 85                  90                  95

Gly Gly Thr Ser Tyr Ser Pro Gln Glu Asn Ser His Asn His Ser Ala
            100                 105                 110

Leu His Ser Ser Asn Ser His Ser Ser Asn Pro Ser Asn Asn Pro Ser
        115                 120                 125

Lys Thr Ser Asp Ala Pro Tyr Asp Xaa Ala Asp Asp Trp Ser Glu His
    130                 135                 140

Ile Ser Ser Ser Gly Lys Lys Tyr Tyr Tyr Asn Ser Ala Arg Asp Lys
145                 150                 155                 160

Met Ala Val Asn Ser Phe Pro Lys Asp Arg Asp Tyr Arg Arg Glu Val
                165                 170                 175

Ile Thr Asp Met Lys Arg Cys Glu Thr Pro Glu Ile Leu His His Gln
            180                 185                 190

Ile Lys Cys Cys Gly Asp Leu Ile Val Leu Lys Thr Asn Thr Val Thr
        195                 200                 205

Ala Gln Val Thr Val Arg Pro Lys Met Cys Ile Leu Thr Glu Leu Glu
    210                 215                 220

Arg Gly Met Val Gly Pro Val Thr Leu His Lys Lys Ile His Thr Thr
225                 230                 235                 240

Thr Val Leu Phe Ile Val Gln Ile His Ile Leu Leu Ile Gln Ala Ile
                245                 250                 255

Thr Gln Ala Lys Leu Gln Met His Leu Met Ile Leu Gln Met Thr Gly
            260                 265                 270

Leu Ser Ile Leu Ala Leu Leu Gly Lys Ser Thr Thr Thr Ile Val Glu
        275                 280                 285

Gln Lys Phe His Asn Gly Lys Asn Gln Lys Ser Gly Leu Lys Glu Asn
    290                 295                 300

Arg Asp Lys Lys Lys Gln Thr Arg Ala Glu Thr His Ser Ser Ser Thr
305                 310                 315                 320

Pro Val Gln His Pro Ile Lys Pro Val Val 
                325                 330



<210> 2504
<211> 232
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2504
Met Ala Val Asp Ile Gln Pro Ala Cys Leu Gly Leu Tyr Cys Gly Lys
  1               5                  10                  15

Thr Leu Leu Phe Lys Asn Gly Ser Thr Glu Ile Tyr Gly Glu Cys Gly
             20                  25                  30

Val Cys Pro Arg Gly Gln Arg Thr Asn Ala Gln Lys Tyr Cys Gln Pro
         35                  40                  45

Cys Thr Glu Ser Pro Glu Leu Tyr Asp Trp Leu Tyr Leu Gly Phe Met
     50                  55                  60

Ala Met Leu Pro Leu Val Leu His Trp Phe Phe Ile Glu Trp Tyr Ser
 65                  70                  75                  80

Gly Lys Lys Ser Ser Ser Ala Leu Phe Gln His Ile Thr Ala Leu Phe
                 85                  90                  95

Glu Cys Ser Met Ala Ala Ile Ile Thr Leu Leu Val Ser Asp Pro Val
            100                 105                 110

Gly Val Leu Tyr Ile Arg Ser Cys Arg Val Leu Met Leu Ser Asp Trp
        115                 120                 125

Tyr Thr Met Leu Tyr Asn Pro Ser Pro Asp Tyr Val Thr Thr Val His
    130                 135                 140

Cys Thr His Glu Ala Val Tyr Pro Leu Tyr Thr Ile Val Phe Ile Tyr
145                 150                 155                 160

Tyr Ala Phe Cys Leu Val Leu Met Met Leu Leu Arg Pro Leu Leu Val
                165                 170                 175

Lys Lys Ile Ala Cys Gly Leu Gly Lys Ser Asp Arg Phe Lys Ser Ile
            180                 185                 190

Tyr Ala Ala Leu Tyr Phe Phe Pro Ile Leu Thr Val Leu Gln Ala Val
        195                 200                 205

Gly Gly Gly Leu Leu Tyr Tyr Ala Phe Pro Tyr Ile Lys Leu Val Trp
    210                 215                 220

Gly Phe Ser Ser Arg Arg Xaa Pro 
225                 230



<210> 2505
<211> 160
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (151)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2505
Met Ala Cys Leu Gly Leu Tyr Cys Gly Lys Thr Leu Leu Phe Lys Asn
  1               5                  10                  15

Gly Ser Thr Glu Ile Tyr Gly Glu Cys Gly Val Cys Pro Arg Gly Gln
             20                  25                  30

Arg Thr Asn Ala Gln Lys Tyr Cys Gln Pro Cys Thr Glu Ser Pro Glu
         35                  40                  45

Leu Tyr Asp Trp Leu Tyr Leu Gly Phe Met Ala Met Leu Pro Leu Val
     50                  55                  60

Leu His Trp Phe Phe Ile Glu Trp Tyr Ser Gly Lys Lys Ser Ser Ser
 65                  70                  75                  80

Ala Leu Phe Gln His Ile Thr Ala Leu Phe Glu Cys Ser Met Ala Ala
                 85                  90                  95

Ile Ile Thr Leu Leu Val Ser Asp Pro Val Gly Val Leu Tyr Ile Arg
            100                 105                 110

Ser Cys Arg Val Leu Met Leu Ser Asp Trp Tyr Thr Met Leu Tyr Asn
        115                 120                 125

Pro Ser Pro Asp Tyr Val Thr Thr Val His Cys Thr His Glu Ala Ala
    130                 135                 140

Thr His Tyr Ile Pro Leu Xaa Leu Ser Ile Thr His Ser Ala Trp Tyr
145                 150                 155                 160






<210> 2506
<211> 166
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2506
Met Ser Gly Phe Glu Asn Leu Asn Thr Asp Phe Tyr Gln Thr Ser Tyr
  1               5                  10                  15

Ser Ile Asp Asp Gln Ser Gln Gln Ser Tyr Asp Tyr Gly Gly Ser Gly
             20                  25                  30

Gly Pro Tyr Ser Lys Gln Tyr Ala Gly Tyr Asp Tyr Ser Gln Gln Gly
         35                  40                  45

Arg Phe Val Pro Pro Asp Met Met Gln Pro Gln Gln Pro Tyr Thr Gly
     50                  55                  60

Gln Ile Tyr Gln Pro Thr Gln Ala Tyr Thr Pro Ala Ser Pro Gln Pro
 65                  70                  75                  80

Phe Tyr Gly Asn Asn Phe Glu Asp Glu Pro Pro Leu Leu Glu Glu Leu
                 85                  90                  95

Gly Ile Asn Phe Asp His Ile Trp Gln Lys Thr Leu Thr Val Leu His
            100                 105                 110

Pro Leu Lys Val Ala Asp Gly Ser Ile Met Asn Glu Thr Asp Leu Ala
        115                 120                 125

Gly Pro Met Xaa Phe Cys Leu Ala Phe Gly Ala Thr Leu Leu Leu Ala
    130                 135                 140

Gly Lys Ile Gln Phe Gly Tyr Val Tyr Gly Ile Ser Ala Ile Gly Xaa
145                 150                 155                 160

Leu Gly Met Phe Gly Tyr 
                165



<210> 2507
<211> 142
<212> PRT
<213> Homo sapiens

<400> 2507
Met Pro Thr Thr Pro Gln Ala Glu Gly Ser Pro Leu Arg Pro Ala Gly
  1               5                  10                  15

Gly Ala Ala Ala Val Cys Pro Ile Gln Thr Ser Ser Lys Glu Pro Asp
             20                  25                  30

Ile Phe Pro Ser Ile Tyr Glu Glu Ser His Leu Thr Glu His Gly His
         35                  40                  45

Arg Gln Leu Ala Leu Pro His Gln Gly Met Gly Ile Ser Pro Thr Tyr
     50                  55                  60

Ser His Pro Cys Thr Pro Asp Phe Thr Pro Gly Pro Arg Val Gln Leu
 65                  70                  75                  80

Met Ala Glu Pro Leu Leu Val Pro Ser Asn Lys Lys Ser Asn Thr Tyr
                 85                  90                  95

Gly Leu Val Tyr Thr Ser Ile Leu Gly Tyr Asn Arg Asn Val Ile Lys
            100                 105                 110

Leu Ser Glu Gln Asp Glu Val Leu Pro Val Asp Ile His Gln Gly Gly
        115                 120                 125

Leu Gly Thr Leu Val Ala Ala Cys Leu Ala Ala Trp Ala Leu 
    130                 135                 140



<210> 2508
<211> 545
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (419)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2508
Met Leu Leu Asn Asn Gly Phe Arg Glu Ser Asp Gln Leu Phe Lys Gln
  1               5                  10                  15

Tyr Arg Asn His Ser Pro Leu Met Ser Phe Gly Ala Ser Phe Val Ser
             20                  25                  30

Phe Leu Asn Ala Met Met Thr Phe Glu Glu Glu Lys Met Gln Leu Ala
         35                  40                  45

Cys Asp Asp Leu Lys Thr Thr Glu Lys Leu Cys Glu Ser Glu Glu Ala
     50                  55                  60

Gly Val Ile Glu Thr Ile Lys Asn Lys Ile Lys Lys Asn Val Asp Val
 65                  70                  75                  80

Arg Lys Ser Ala Pro Ser Met Val Asp Arg Leu Gln Arg Gln Ile Ile
                 85                  90                  95

Ile Ala Asp Cys Gln Val Tyr Leu Ala Val Leu Ser Phe Val Lys Gln
            100                 105                 110

Glu Leu Ser Ala Tyr Ile Lys Gly Gly Trp Ile Leu Arg Lys Ala Trp
        115                 120                 125

Lys Ile Tyr Asn Lys Cys Tyr Leu Asp Ile Asn Ala Leu Gln Glu Leu
    130                 135                 140

Tyr Gln Lys Lys Leu Thr Glu Glu Ser Leu Thr Ser Asp Ala Ala Asn
145                 150                 155                 160

Asp Asn His Ile Val Ala Glu Gly Val Ser Glu Glu Ser Leu Asn Arg
                165                 170                 175

Leu Lys Gly Ala Val Ser Phe Gly Tyr Gly Leu Phe His Leu Cys Ile
            180                 185                 190

Ser Met Val Pro Pro Asn Leu Leu Lys Ile Ile Asn Leu Leu Gly Phe
        195                 200                 205

Pro Gly Asp Arg Leu Gln Gly Leu Ser Ser Leu Met Tyr Ala Ser Glu
    210                 215                 220

Ser Lys Asp Met Lys Ala Pro Leu Ala Thr Leu Ala Leu Leu Trp Tyr
225                 230                 235                 240

His Thr Val Val Arg Pro Phe Phe Ala Leu Asp Gly Ser Asp Asn Lys
                245                 250                 255

Ala Gly Leu Asp Glu Ala Lys Glu Ile Leu Leu Lys Lys Glu Ala Ala
            260                 265                 270

Tyr Pro Asn Ser Ser Leu Phe Met Phe Phe Lys Gly Arg Ile Gln Arg
        275                 280                 285

Leu Glu Cys Gln Ile Asn Ser Ala Leu Thr Ser Phe His Thr Ala Leu
    290                 295                 300

Glu Leu Ala Val Asp Gln Arg Glu Ile Gln His Val Cys Leu Tyr Glu
305                 310                 315                 320

Ile Gly Trp Cys Ser Met Ile Glu Leu Asn Phe Lys Asp Ala Phe Asp
                325                 330                 335

Ser Phe Glu Arg Leu Lys Asn Glu Ser Arg Trp Ser Gln Cys Tyr Tyr
            340                 345                 350

Ala Tyr Leu Thr Ala Val Cys Gln Gly Ala Thr Gly Asp Val Asp Gly
        355                 360                 365

Ala Gln Ile Val Phe Lys Glu Val Gln Lys Leu Phe Lys Arg Lys Asn
    370                 375                 380

Asn Gln Ile Glu Gln Phe Ser Val Lys Lys Ala Glu Arg Phe Arg Lys
385                 390                 395                 400

Gln Thr Pro Thr Lys Ala Leu Cys Val Leu Ala Ser Ile Glu Val Leu
                405                 410                 415

Tyr Leu Xaa Lys Ala Leu Pro Asn Cys Ser Phe Pro Asn Leu Gln Arg
            420                 425                 430

Met Ser Gln Ala Cys His Glu Val Asp Asp Ser Ser Val Val Gly Leu
        435                 440                 445

Lys Tyr Leu Leu Leu Gly Ala Ile His Lys Cys Leu Gly Asn Ser Glu
    450                 455                 460

Asp Ala Val Gln Tyr Phe Gln Arg Ala Val Lys Asp Glu Leu Cys Arg
465                 470                 475                 480

Gln Asn Asn Leu Tyr Val Gln Pro Tyr Ala Cys Tyr Glu Leu Gly Cys
                485                 490                 495

Leu Leu Leu Asp Lys Pro Glu Thr Val Gly Arg Gly Arg Ala Leu Leu
            500                 505                 510

Leu Gln Ala Lys Glu Asp Phe Ser Gly Tyr Asp Phe Glu Asn Arg Leu
        515                 520                 525

His Val Arg Ile His Ala Ala Leu Ala Ser Leu Arg Glu Leu Val Pro
    530                 535                 540

Gln 
545



<210> 2509
<211> 210
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (207)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2509
Met Lys Val Asn Asp Arg Val Ala Ala Glu Arg Gln His Val Leu Ala
  1               5                  10                  15

Phe Ala Leu Ala Gly Gly Val Leu Leu Leu Met Ala Val Val Val Ala
             20                  25                  30

Leu Ser Phe Gly Arg Asp Ala His Gly Trp Thr Trp Ala Ser Gly Ala
         35                  40                  45

Leu Leu Glu Asp Leu Met Pro Trp Arg Trp Pro Arg Ile Met Ala Ala
     50                  55                  60

Leu Phe Ala Gly Xaa Met Leu Ala Val Ala Gly Cys Ile Ile Xaa Xaa
 65                  70                  75                  80

Leu Thr Gly Asn Pro Met Ala Ser Pro Glu Val Leu Gly Ile Ser Ser
                 85                  90                  95

Gly Ala Ala Phe Gly Val Val Leu Met Leu Phe Leu Val Pro Gly Asn
            100                 105                 110

Ala Phe Gly Trp Leu Leu Pro Ala Gly Ser Leu Gly Ala Xaa Val Thr
        115                 120                 125

Leu Leu Ile Ile Met Ile Ala Ala Gly Arg Gly Gly Phe Ser Pro His
    130                 135                 140

Arg Met Leu Leu Ala Gly Met Ala Leu Ser Thr Ala Phe Thr Met Leu
145                 150                 155                 160

Leu Met Met Leu Gln Ala Ser Gly Asp Pro Arg Met Ala Gln Val Leu
                165                 170                 175

Thr Trp Ile Ser Gly Ser Thr Tyr Asn Ala Thr Asp Ala Gln Val Trp
            180                 185                 190

Arg Thr Gly Ile Val Trp Tyr Phe Ala Ala Ile Thr Pro Leu Xaa Arg
        195                 200                 205

Ala Gly 
    210



<210> 2510
<211> 108
<212> PRT
<213> Homo sapiens

<400> 2510
Met Val Leu Pro Pro Ser Ser Glu Lys Val Lys Ser Leu Ser Gln Thr
  1               5                  10                  15

Pro Arg Val Glu Ala Ser Gly Arg Gly Ser Trp Gln Glu Met Gly Leu
             20                  25                  30

Val Glu Arg Leu Leu Leu Cys Phe His Ser Arg Pro Val Ala Val Cys
         35                  40                  45

Ser Asp Ser Ser His Gln Asp Thr Ile Gly Ser Phe Cys Met Thr Leu
     50                  55                  60

Pro Pro Arg Val Phe Leu Arg Phe Ser Leu Ser Cys Leu Ile Leu Trp
 65                  70                  75                  80

Leu Phe Pro Tyr Leu Phe Leu Leu Asp Cys Gly Arg Lys Lys Ser Ile
                 85                  90                  95

Ser Asn Leu Leu Lys Pro Val Thr Lys Gln Gln Gln 
            100                 105



<210> 2511
<211> 124
<212> PRT
<213> Homo sapiens

<400> 2511
Met Phe Val Tyr Ile Val Phe Leu Phe Gly Phe Ser Thr Ala Val Val
  1               5                  10                  15

Thr Leu Ile Glu Asp Gly Lys Asn Asp Ser Leu Pro Ser Glu Ser Thr
             20                  25                  30

Ser His Arg Trp Arg Gly Pro Ala Cys Arg Pro Pro Asp Ser Ser Tyr
         35                  40                  45

Asn Ser Leu Tyr Ser Thr Cys Leu Glu Leu Phe Lys Phe Thr Ile Gly
     50                  55                  60

Met Gly Asp Leu Glu Phe Thr Glu Asn Tyr Asp Phe Lys Ala Val Phe
 65                  70                  75                  80

Ile Ile Leu Leu Leu Ala Tyr Val Ile Leu Thr Tyr Ile Leu Leu Leu
                 85                  90                  95

Asn Met Leu Ile Ala Leu Met Gly Glu Thr Val Asn Lys Ile Ala Gln
            100                 105                 110

Glu Ser Lys Asn Ile Trp Lys Leu Gln Arg Ala Ile 
        115                 120



<210> 2512
<211> 376
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (285)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2512
Met Asp Gly Glu Glu Gln Gln Pro Pro His Glu Ala Asn Val Glu Pro
  1               5                  10                  15

Val Val Pro Ser Glu Ala Ser Glu Pro Val Pro Arg Val Leu Ser Gly
             20                  25                  30

Asp Pro Gln Asn Leu Ser Asp Val Asp Ala Phe Asn Leu Leu Leu Glu
         35                  40                  45

Met Lys Leu Lys Arg Arg Arg Gln Arg Pro Asn Leu Pro Arg Thr Val
     50                  55                  60

Thr Gln Leu Val Ala Glu Asp Gly Ser Arg Val Tyr Val Val Gly Thr
 65                  70                  75                  80

Ala His Phe Ser Asp Asp Ser Lys Arg Asp Val Val Lys Thr Ile Arg
                 85                  90                  95

Glu Val Gln Pro Asp Val Val Val Val Glu Leu Cys Gln Tyr Arg Val
            100                 105                 110

Ser Met Leu Lys Met Asp Glu Ser Thr Leu Leu Arg Glu Ala Gln Glu
        115                 120                 125

Leu Ser Leu Glu Lys Leu Gln Gln Ala Val Arg Gln Asn Gly Leu Met
    130                 135                 140

Ser Gly Leu Met Gln Met Leu Leu Leu Lys Val Ser Ala His Ile Thr
145                 150                 155                 160

Glu Gln Leu Gly Met Ala Pro Gly Gly Glu Phe Arg Glu Ala Phe Lys
                165                 170                 175

Glu Ala Ser Lys Val Pro Phe Cys Lys Phe His Leu Gly Asp Arg Pro
            180                 185                 190

Ile Pro Val Thr Phe Lys Arg Ala Ile Ala Ala Leu Ser Phe Trp Gln
        195                 200                 205

Lys Val Arg Leu Ala Trp Gly Leu Cys Phe Leu Ser Asp Pro Ile Ser
    210                 215                 220

Lys Asp Asp Val Glu Arg Cys Lys Gln Lys Asp Leu Leu Glu Gln Met
225                 230                 235                 240

Met Ala Glu Met Ile Gly Glu Phe Pro Asp Leu His Arg Thr Ile Val
                245                 250                 255

Ser Glu Arg Asp Val Tyr Leu Thr Tyr Met Leu Arg Gln Ala Ala Arg
            260                 265                 270

Arg Leu Glu Leu Pro Arg Ala Ser Asp Ala Glu Pro Xaa Lys Cys Val
        275                 280                 285

Pro Ser Val Val Val Gly Val Val Gly Met Gly His Val Pro Gly Ile
    290                 295                 300

Glu Lys Asn Trp Ser Thr Asp Leu Asn Ile Gln Glu Ile Met Thr Val
305                 310                 315                 320

Pro Pro Pro Ser Val Ser Gly Arg Val Ser Arg Leu Ala Val Lys Ala
                325                 330                 335

Ala Phe Phe Gly Leu Leu Gly Tyr Ser Leu Tyr Trp Met Gly Arg Arg
            340                 345                 350

Thr Ala Ser Leu Val Leu Ser Leu Pro Ala Ala Gln Tyr Cys Leu Gln
        355                 360                 365

Arg Val Thr Glu Ala Arg His Lys 
    370                 375



<210> 2513
<211> 350
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2513
Met Lys Lys Asp Glu Ser Phe Leu Gly Lys Leu Gly Xaa Thr Leu Ala
  1               5                  10                  15

Arg Lys Arg Arg Ala Arg Glu Val Ser Asp Leu Gln Glu Glu Gly Lys
             20                  25                  30

Asn Ala Ile Asn Ser Pro Met Ser Pro Ala Leu Ala Xaa Val His Pro
         35                  40                  45

Glu Asp Thr Gln Leu Glu Glu Asn Glu Glu Arg Thr Met Ile Asp Pro
     50                  55                  60

Thr Ser Lys Glu Asp Pro Lys Phe Lys Glu Leu Val Lys Val Leu Leu
 65                  70                  75                  80

Asp Trp Ile Asn Asp Val Leu Val Glu Glu Arg Ile Ile Val Lys Gln
                 85                  90                  95

Leu Glu Glu Asp Leu Tyr Asp Gly Gln Val Leu Gln Lys Leu Leu Glu
            100                 105                 110

Lys Leu Ala Gly Cys Lys Leu Asn Val Ala Xaa Val Thr Gln Ser Glu
        115                 120                 125

Ile Gly Gln Lys Gln Lys Leu Gln Thr Val Leu Glu Ala Val His Asp
    130                 135                 140

Leu Leu Arg Pro Arg Gly Trp Ala Leu Arg Trp Ser Val Asp Ser Ile
145                 150                 155                 160

His Gly Lys Asn Leu Val Ala Ile Leu His Leu Leu Val Ser Leu Ala
                165                 170                 175

Met His Phe Arg Ala Pro Ile Arg Leu Pro Glu His Val Thr Val Gln
            180                 185                 190

Val Val Val Val Arg Lys Arg Glu Gly Leu Leu His Ser Ser His Ile
        195                 200                 205

Ser Glu Glu Leu Thr Thr Thr Thr Glu Met Met Met Gly Arg Phe Glu
    210                 215                 220

Arg Asp Ala Phe Asp Thr Leu Phe Asp His Ala Pro Asp Lys Leu Ser
225                 230                 235                 240

Val Val Lys Lys Ser Leu Ile Thr Phe Val Asn Lys His Leu Asn Lys
                245                 250                 255

Leu Asn Leu Glu Val Thr Glu Leu Glu Thr Gln Phe Ala Asp Gly Val
            260                 265                 270

Tyr Leu Val Leu Leu Met Gly Leu Leu Glu Asp Tyr Phe Val Pro Leu
        275                 280                 285

His His Phe Tyr Leu Thr Pro Glu Ser Phe Asp Gln Lys Val His Asn
    290                 295                 300

Val Ser Phe Ala Phe Glu Leu Met Leu Asp Gly Gly Leu Lys Lys Pro
305                 310                 315                 320

Lys Ala Arg Pro Glu Asp Val Val Asn Leu Asp Leu Lys Ser Thr Leu
                325                 330                 335

Arg Val Leu Tyr Asn Leu Phe Thr Lys Tyr Lys Asn Val Glu 
            340                 345                 350



<210> 2514
<211> 198
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (31)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2514
Met Ala Pro Glu Glu Lys Gly Asp Lys Asp Asp Gln Leu Asn Lys Glu
  1               5                  10                  15

Thr Glu Asp Tyr Leu Asn Ser Leu Leu Glu Gly Cys Leu Lys Xaa Thr
             20                  25                  30

Glu Asp Ser Leu Ser Tyr Glu Asp Asn Gln Asp Asp Asp Ser Asp Leu
         35                  40                  45

Leu Gln Asp Leu Ser Pro Glu Glu Ala Ser Tyr Ser Leu Gln Glu Asn
     50                  55                  60

Leu Pro Ser Asp Glu Ser Cys Leu Ser Leu Asp Asp Leu Ala Lys Arg
 65                  70                  75                  80

Ile Glu Ile Ala Glu Val Val Pro Thr Glu Gly Leu Val Ser Ile Leu
                 85                  90                  95

Lys Lys Arg Asn Asp Thr Val Gly Asp His Pro Ala Gln Met Gln His
            100                 105                 110

Lys Pro Ser Lys Arg Arg Val Arg Phe Gln Glu Ile Asp Asp Ser Leu
        115                 120                 125

Asp Gln Asp Glu Val Gly Gly Gly Ser Cys Ile Leu Leu Val Leu Leu
    130                 135                 140

Cys Ile Ala Thr Val Phe Leu Ser Val Gly Gly Thr Ala Leu Tyr Cys
145                 150                 155                 160

Thr Phe Gly Asp Met Glu Ser Pro Val Cys Thr Asp Phe Ala Asp Asn
                165                 170                 175

Met Asp Phe Tyr Tyr Thr Lys Leu Leu Gln Gly Val Ala Glu Leu Lys
            180                 185                 190

His Trp Ile Tyr Leu Ser 
        195



<210> 2515
<211> 151
<212> PRT
<213> Homo sapiens

<400> 2515
Met Lys Tyr Gly Leu Thr Gly Pro Trp Ile Lys Arg Leu Leu Pro Val
  1               5                  10                  15

Ile Phe Leu Val Gln Ala Ser Gly Met Asn Val Tyr Met Ser Arg Ser
             20                  25                  30

Leu Glu Ser Ile Lys Gly Ile Ala Val Met Asp Lys Glu Gly Asn Val
         35                  40                  45

Leu Gly His Ser Arg Ile Ala Gly Thr Lys Ala Val Arg Glu Thr Leu
     50                  55                  60

Ala Ser Arg Ile Val Leu Phe Gly Thr Ser Ala Leu Ile Pro Glu Val
 65                  70                  75                  80

Phe Thr Tyr Phe Phe Lys Arg Thr Gln Tyr Phe Arg Lys Asn Pro Gly
                 85                  90                  95

Ser Leu Trp Ile Leu Lys Leu Ser Cys Thr Val Leu Ala Met Gly Leu
            100                 105                 110

Met Val Pro Phe Ser Phe Ser Ile Phe Pro Gln Ile Gly Gln Ile Gln
        115                 120                 125

Tyr Cys Ser Leu Glu Glu Lys Ile Gln Ser Pro Thr Glu Glu Thr Glu
    130                 135                 140

Ile Phe Tyr His Arg Gly Val 
145                 150



<210> 2516
<211> 307
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2516
Met Ala Ala Pro His His Val Lys Pro Lys Thr Ser Pro Lys Ala Arg
  1               5                  10                  15

Pro Arg His Val Gly Leu Gly Arg Trp Leu Gly Ala Thr Gly Gly Ala
             20                  25                  30

Xaa Leu Trp Ile Gln Glu Thr Val Pro Thr Trp Ala Ser Arg His Pro
         35                  40                  45

Cys Ser His Leu Cys Cys His Cys Ser Lys Gln Gln Ser Leu Trp Lys
     50                  55                  60

His Leu Cys His Gly His Arg Pro Ala Val Ser Gly Leu Gln Met Gly
 65                  70                  75                  80

Leu Cys Ile Leu Ala Lys Arg His Pro His Thr Gly Gly Gly Cys Leu
                 85                  90                  95

Leu Trp Thr Tyr His Pro Arg Arg Thr Glu Pro Xaa Pro Ala His Cys
            100                 105                 110

Pro Gly Trp Arg Gly Ala Gln Gln Met Pro Arg Leu Arg Ala Phe Ala
        115                 120                 125

Asn Thr Cys Pro His Arg Ala Ser Val Leu Leu Pro Cys Ala Arg Leu
    130                 135                 140

Ala Ser Pro Met Pro Ala Gly Trp Leu Gly Pro Val Glu Ala Ser Ser
145                 150                 155                 160

Gly Val Ala Pro Ala Pro Arg Leu Pro Val Ser Ser Pro Val Leu Ser
                165                 170                 175

Thr Ser Ala Asn Ser Arg Gly Glu Ala Lys Glu Thr Gln Gly Val Gln
            180                 185                 190

Glu Val Gly Ala Leu His Pro Ser Arg Ser Phe Pro Gly Ser Ser Ala
        195                 200                 205

Ser Leu Ser His Ala Pro Arg Xaa His Ser Arg Gln Gly Gly Arg Gln
    210                 215                 220

Gly Arg Gly Val Gly Pro Glu Leu Ser Thr Ala Pro Ser Pro Pro His
225                 230                 235                 240

His Pro Phe Pro Phe His Arg Trp Gly Arg Gly Glu Gly Gly Ala Gly
                245                 250                 255

Trp Gly Trp Arg Val Pro Pro Thr Thr Leu Leu Cys Leu Gly Thr Pro
            260                 265                 270

Thr Pro His Ser Pro His Pro Asn Ile Leu Val Ser Val Pro Val Gly
        275                 280                 285

Leu Ala Cys Met Cys Thr Tyr Val Phe Val Thr Phe Leu Trp Lys Lys
    290                 295                 300

Lys Lys Lys 
305



<210> 2517
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2517
Met Ile Ile Ala Ser Val Val Ser Ala Val Gln Met Leu Ile Asn Ala
  1               5                  10                  15

Tyr Ala Phe Gly Leu Tyr Gln Ser Leu Gly Ile Phe Ile Pro Leu Ile
             20                  25                  30

Val Thr Asn Cys Ile Val Val Gly Arg Ala Glu Ala Phe Ala Ala Lys
         35                  40                  45

Lys Gly Pro Ala Leu Ser Ala Leu Asp Gly Phe Ser Ile Gly Met Gly
     50                  55                  60

Ala Thr Cys Ala Met Phe Val Leu Gly Ser Leu Arg Glu Ile Ile Gly
 65                  70                  75                  80

Asn Gly Thr Leu Phe Asp Gly Ala Asp Ala Leu Leu Gly Ser Trp Ala
                 85                  90                  95

Lys Val Leu Arg Val Glu Ile Phe His Thr Asp Ser Pro Phe Leu Leu
            100                 105                 110

Ala Met Leu Pro Pro Xaa Ala Phe Ile Gly Leu Gly Leu Met Leu Ala
        115                 120                 125

Gly Lys Tyr Leu Ile Asp Glu Arg Met Lys Ser 
    130                 135



<210> 2518
<211> 478
<212> PRT
<213> Homo sapiens

<400> 2518
Met Gly Ser Ala Phe Glu Arg Val Val Arg Arg Val Val Gln Glu Leu
  1               5                  10                  15

Asp His Gly Gly Glu Phe Ile Pro Val Thr Ser Leu Gln Ser Ser Thr
             20                  25                  30

Gly Phe Gln Pro Tyr Cys Leu Val Val Arg Lys Pro Ser Ser Ser Trp
         35                  40                  45

Phe Trp Lys Pro Arg Tyr Lys Cys Val Asn Leu Ser Ile Lys Asp Ile
     50                  55                  60

Leu Glu Pro Asp Ala Ala Glu Pro Asp Val Gln Arg Gly Arg Ser Phe
 65                  70                  75                  80

His Phe Tyr Asp Ala Met Asp Gly Gln Ile Gln Gly Ser Val Glu Leu
                 85                  90                  95

Ala Ala Pro Gly Gln Ala Lys Ile Ala Gly Gly Ala Ala Val Ser Asp
            100                 105                 110

Ser Ser Ser Thr Ser Met Asn Val Tyr Ser Leu Ser Val Asp Pro Asn
        115                 120                 125

Thr Trp Gln Thr Leu Leu His Glu Arg His Leu Arg Gln Pro Glu His
    130                 135                 140

Lys Val Leu Gln Gln Leu Arg Ser Arg Gly Asp Asn Val Tyr Val Val
145                 150                 155                 160

Thr Glu Val Leu Gln Thr Gln Lys Glu Val Glu Val Thr Arg Thr His
                165                 170                 175

Lys Arg Glu Gly Ser Gly Arg Phe Ser Leu Pro Gly Ala Thr Cys Leu
            180                 185                 190

Gln Gly Glu Gly Gln Gly His Leu Ser Gln Lys Lys Thr Val Thr Ile
        195                 200                 205

Pro Ser Gly Ser Thr Leu Ala Phe Arg Val Ala Gln Leu Val Ile Asp
    210                 215                 220

Ser Asp Leu Asp Val Leu Leu Phe Pro Asp Lys Lys Gln Arg Thr Phe
225                 230                 235                 240

Gln Pro Pro Ala Thr Gly His Lys Arg Ser Thr Ser Glu Gly Ala Trp
                245                 250                 255

Pro Gln Leu Pro Ser Gly Leu Ser Met Met Arg Cys Leu His Asn Phe
            260                 265                 270

Leu Thr Asp Gly Val Pro Ala Glu Gly Ala Phe Thr Glu Asp Phe Gln
        275                 280                 285

Gly Leu Arg Ala Glu Val Glu Thr Ile Ser Lys Glu Leu Glu Leu Leu
    290                 295                 300

Asp Arg Glu Leu Cys Gln Leu Leu Leu Glu Gly Leu Glu Gly Val Leu
305                 310                 315                 320

Arg Asp Gln Leu Ala Leu Arg Ala Leu Glu Glu Ala Leu Glu Gln Gly
                325                 330                 335

Gln Ser Leu Gly Pro Val Glu Pro Leu Asp Gly Pro Ala Gly Ala Val
            340                 345                 350

Leu Glu Cys Leu Val Leu Ser Ser Gly Met Leu Val Pro Glu Leu Ala
        355                 360                 365

Ile Pro Val Val Tyr Leu Leu Gly Ala Leu Thr Met Leu Ser Glu Thr
    370                 375                 380

Gln His Lys Leu Leu Ala Glu Ala Leu Glu Ser Gln Thr Leu Leu Gly
385                 390                 395                 400

Pro Leu Glu Leu Val Gly Ser Leu Leu Glu Gln Ser Ala Pro Trp Gln
                405                 410                 415

Glu Arg Ser Thr Met Ser Leu Pro Pro Gly Leu Leu Gly Asn Ser Trp
            420                 425                 430

Gly Glu Gly Ala Pro Ala Trp Val Leu Leu Asp Glu Cys Gly Leu Glu
        435                 440                 445

Leu Gly Glu Asp Thr Pro His Val Cys Trp Glu Pro Gln Pro Arg Ala
    450                 455                 460

Ala Cys Val His Ser Thr Pro Pro Trp His Cys Tyr Gln Asp 
465                 470                 475



<210> 2519
<211> 215
<212> PRT
<213> Homo sapiens

<400> 2519
Met Val Ala Ala Ala Leu Thr Asp Leu Asp Asp Arg Leu Ala Gly Arg
  1               5                  10                  15

Leu Arg Asn Leu Ile Ile Thr Leu Phe Cys Phe Phe Ile Ala Ser Ala
             20                  25                  30

Ser Val Glu Leu Leu Phe Pro Trp Pro Trp Leu Phe Ala Ile Gly Leu
         35                  40                  45

Thr Leu Ser Thr Ser Gly Phe Ile Leu Leu Gly Gly Leu Gly Gln Arg
     50                  55                  60

Tyr Ala Thr Ile Ala Phe Gly Ala Leu Leu Ile Ala Ile Tyr Thr Met
 65                  70                  75                  80

Leu Gly Thr Ser Leu Tyr Glu His Trp Tyr Gln Gln Pro Met Tyr Leu
                 85                  90                  95

Leu Ala Gly Ala Val Trp Tyr Asn Val Leu Thr Leu Ile Gly His Leu
            100                 105                 110

Leu Phe Pro Val Arg Pro Leu Gln Asp Asn Leu Ala Arg Cys Tyr Glu
        115                 120                 125

Gln Leu Ala Arg Tyr Leu Glu Leu Lys Ser Arg Met Phe Asp Pro Asp
    130                 135                 140

Ile Glu Asp Gln Ser Gln Ala Pro Leu Tyr Asp Leu Ala Leu Ala Asn
145                 150                 155                 160

Gly Leu Leu Met Ala Thr Leu Asn Gln Thr Lys Leu Ser Leu Leu Thr
                165                 170                 175

Arg Leu Arg Gly Asp Arg Gly Gln Arg Gly Thr Arg Arg Thr Leu Ala
            180                 185                 190

Leu Leu Leu Cys Arg Thr Gly Tyr Ser Arg Ala Cys Gln Leu Phe Ser
        195                 200                 205

Tyr Ser Val Ser Asn Ile Ala 
    210                 215



<210> 2520
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2520
Met Gly Trp Ala His Pro Leu Leu Cys Gly Gly Gly Gly Pro Pro Ala
  1               5                  10                  15

Leu Ala Val Thr Ile Leu His Arg Thr Val Leu Gly Ser Leu Pro Leu
             20                  25                  30

Pro Xaa Ala Pro Arg Ser Ala Ala Leu Arg Leu Asn Met Ser Ala Arg
         35                  40                  45

Pro Cys Gln Cys Cys Gly Thr Pro Val Arg Ala Ser Asp Cys Val Cys
     50                  55                  60

Arg Arg Asp Ala Gly Thr Arg Gly Cys Val Cys Met Cys Val Cys Val
 65                  70                  75                  80

Arg Ala Ala Cys Pro Pro Val Cys Met Val Cys Gly Leu Gly Pro His
                 85                  90                  95

Pro Trp Pro Glu His Phe Ile Leu Trp Gly Arg Gly Ala Asp Leu Val
            100                 105                 110

Gly Gly Ala Pro Leu 
        115



<210> 2521
<211> 160
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2521
Met Thr Pro Gly Asn Ile Leu Thr Arg Pro Ala Ser Trp Met Ala Val
  1               5                  10                  15

Phe Asn Ala Met Pro Thr Ile Cys Phe Gly Phe Gln Cys His Val Ser
             20                  25                  30

Ser Val Pro Val Phe Asn Ser Met Gln Gln Pro Glu Val Lys Thr Trp
         35                  40                  45

Gly Gly Val Val Thr Ala Ala Met Val Ile Ala Leu Ala Val Tyr Met
     50                  55                  60

Gly Thr Gly Ile Cys Gly Phe Leu Thr Phe Gly Ala Ala Val Asp Pro
 65                  70                  75                  80

Asp Val Leu Leu Ser Tyr Pro Ser Glu Asp Met Ala Val Ala Val Ala
                 85                  90                  95

Arg Ala Phe Ile Ile Leu Ser Val Leu Thr Ser Tyr Pro Ile Leu His
            100                 105                 110

Phe Cys Gly Arg Ala Val Val Glu Gly Leu Cys Cys Xaa Thr Arg Gly
        115                 120                 125

Cys Gln Trp Arg Arg Thr Trp Gly Gly Ser Gly Gly Gly Glu Cys Cys
    130                 135                 140

Arg Arg Trp Ser Gly Ser Cys Ser Pro Cys Cys Gly Ala Leu His Pro
145                 150                 155                 160






<210> 2522
<211> 237
<212> PRT
<213> Homo sapiens

<400> 2522
Met Leu Phe Tyr Arg Leu Val Phe Ile Leu His Glu Thr Ser Arg Ser
  1               5                  10                  15

Thr Gln Lys Ala Ile Ala Phe Cys Leu Gly Tyr Gly Cys Pro Leu Ala
             20                  25                  30

Ile Ser Val Ile Thr Leu Gly Ala Thr Gln Pro Arg Glu Val Tyr Thr
         35                  40                  45

Arg Lys Asn Val Cys Trp Leu Asn Trp Glu Asp Thr Lys Ala Leu Leu
     50                  55                  60

Ala Phe Ala Ile Pro Ala Leu Ile Ile Val Val Val Asn Ile Thr Ile
 65                  70                  75                  80

Thr Ile Val Val Ile Thr Lys Ile Leu Arg Pro Ser Ile Gly Asp Lys
                 85                  90                  95

Pro Cys Lys Gln Glu Lys Ser Ser Leu Phe Gln Ile Ser Lys Ser Ile
            100                 105                 110

Gly Val Leu Thr Pro Leu Leu Gly Leu Thr Trp Gly Phe Gly Leu Thr
        115                 120                 125

Thr Val Phe Pro Gly Thr Asn Leu Val Phe His Ile Ile Phe Ala Ile
    130                 135                 140

Leu Asn Val Phe Gln Gly Leu Phe Ile Leu Leu Phe Gly Cys Leu Trp
145                 150                 155                 160

Asp Leu Lys Val Gln Glu Ala Leu Leu Asn Lys Phe Ser Leu Ser Arg
                165                 170                 175

Trp Ser Ser Gln His Ser Lys Ser Thr Ser Leu Gly Ser Ser Thr Pro
            180                 185                 190

Val Phe Ser Met Ser Ser Pro Ile Ser Arg Arg Phe Asn Asn Leu Phe
        195                 200                 205

Gly Lys Thr Gly Thr Tyr Asn Val Ser Thr Pro Glu Ala Thr Ser Ser
    210                 215                 220

Ser Leu Glu Asn Ser Ser Ser Ala Ser Ser Leu Leu Asn 
225                 230                 235



<210> 2523
<211> 162
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2523
Met Xaa Asn Ala Ser Tyr Ser Asp Ser Tyr Leu Glu Gly Ile Leu Leu
  1               5                  10                  15

Lys Gly Val Phe Thr Cys Glu Pro Trp Ser Val Ser Val Gly Trp Ser
             20                  25                  30

Thr Ser Val Asp Cys Gly Trp Phe Gln Ser Ala Trp Leu Arg Ser Ser
         35                  40                  45

Thr Glu Gly Ser Thr Gly Ala Ala Leu Trp Gln Arg Leu Arg Arg Glu
     50                  55                  60

Met Asp Gln Pro Thr Pro Gly Thr Trp Leu His Gly Ile Arg Lys Gly
 65                  70                  75                  80

Arg Cys Trp Pro Leu Cys Ser Cys Cys Leu Phe Leu Phe Leu Phe Ala
                 85                  90                  95

Phe Asp Leu Val Ala Thr Asp Arg Val Ala Arg Asp Leu Val Phe Ser
            100                 105                 110

Ser Arg His Pro Ser Thr Pro Ala Leu Ser Gln Val Ser Cys Cys His
        115                 120                 125

Ala Asn Ala Met Ser Thr Leu Ala Pro Arg Pro Lys Ser Val Gln Arg
    130                 135                 140

Trp Pro Thr Ser Ser Ser His Tyr Ser Leu Asn Ser Met Tyr His Leu
145                 150                 155                 160

Pro Leu 




<210> 2524
<211> 333
<212> PRT
<213> Homo sapiens

<400> 2524
Met Ser Gln Cys Cys Arg Lys Ile Lys Asp Thr Val Gln Lys Leu Ala
  1               5                  10                  15

Ser Asp His Lys Asp Ile His Ser Ser Val Ser Arg Val Gly Lys Ala
             20                  25                  30

Ile Asp Arg Asn Phe Asp Ser Glu Ile Cys Gly Val Val Ser Asp Ala
         35                  40                  45

Val Trp Asp Ala Arg Glu Gln Gln Gln Gln Ile Leu Gln Met Ala Ile
     50                  55                  60

Val Glu His Leu Tyr Gln Gln Gly Met Leu Ser Val Ala Glu Glu Leu
 65                  70                  75                  80

Cys Gln Glu Ser Thr Leu Asn Val Asp Leu Asp Phe Lys Gln Pro Phe
                 85                  90                  95

Leu Glu Leu Asn Arg Ile Leu Glu Ala Leu His Glu Gln Asp Leu Gly
            100                 105                 110

Pro Ala Leu Glu Trp Ala Val Ser His Arg Gln Arg Leu Leu Glu Leu
        115                 120                 125

Asn Ser Ser Leu Glu Phe Lys Leu His Arg Leu His Phe Ile Arg Leu
    130                 135                 140

Leu Ala Gly Gly Pro Ala Lys Gln Leu Glu Ala Leu Ser Tyr Ala Arg
145                 150                 155                 160

His Phe Gln Pro Phe Ala Arg Leu His Gln Arg Glu Ile Gln Val Met
                165                 170                 175

Met Gly Ser Leu Val Tyr Leu Arg Leu Gly Leu Glu Lys Ser Pro Tyr
            180                 185                 190

Cys His Leu Leu Asp Ser Ser His Trp Ala Glu Ile Cys Glu Thr Phe
        195                 200                 205

Thr Arg Asp Ala Cys Ser Leu Leu Gly Leu Ser Val Glu Ser Pro Leu
    210                 215                 220

Ser Val Ser Phe Ala Ser Gly Cys Val Ala Leu Pro Val Leu Met Asn
225                 230                 235                 240

Ile Lys Ala Val Ile Glu Gln Arg Gln Cys Thr Gly Val Trp Asn His
                245                 250                 255

Lys Asp Glu Leu Pro Ile Glu Ile Glu Leu Gly Met Lys Cys Trp Tyr
            260                 265                 270

His Ser Val Phe Ala Cys Pro Ile Leu Arg Gln Gln Thr Ser Asp Ser
        275                 280                 285

Asn Pro Pro Ile Lys Leu Ile Cys Gly His Val Ile Ser Arg Asp Ala
    290                 295                 300

Leu Asn Lys Leu Ile Asn Gly Gly Lys Leu Lys Cys Pro Tyr Cys Pro
305                 310                 315                 320

Met Glu Gln Asn Pro Ala Asp Gly Lys Arg Ile Ile Phe 
                325                 330



<210> 2525
<211> 583
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (356)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2525
Met Ala Ala Leu Leu His Thr Asn Thr Pro Ser Ile Asn Gln Glu Leu
  1               5                  10                  15

Cys Arg Leu Asn Thr Met Asp Leu Leu Leu Asp Leu Phe Phe Lys Tyr
             20                  25                  30

Thr Trp Asn Asn Phe Leu His Phe Gln Val Glu Leu Cys Ile Ala Ala
         35                  40                  45

Ile Leu Ser His Ala Ala Arg Glu Glu Arg Thr Glu Ala Ser Gly Ser
     50                  55                  60

Glu Ser Arg Val Glu Pro Pro His Glu Asn Gly Asn Arg Ser Leu Glu
 65                  70                  75                  80

Thr Pro Gln Pro Ala Ala Ser Leu Pro Asp Asn Thr Met Val Thr His
                 85                  90                  95

Leu Phe Gln Lys Cys Cys Leu Val Gln Arg Ile Leu Glu Ala Trp Glu
            100                 105                 110

Ala Asn Asp His Thr Gln Ala Ala Gly Gly Met Arg Arg Gly Asn Met
        115                 120                 125

Gly His Leu Thr Arg Ile Ala Asn Ala Val Val Gln Asn Leu Glu Arg
    130                 135                 140

Gly Pro Val Gln Thr His Ile Ser Glu Val Ile Arg Gly Leu Pro Ala
145                 150                 155                 160

Asp Cys Arg Gly Arg Trp Glu Ser Phe Val Glu Glu Thr Leu Thr Glu
                165                 170                 175

Thr Asn Arg Arg Asn Thr Val Asp Leu Ala Phe Ser Asp Tyr Gln Ile
            180                 185                 190

Gln Gln Met Thr Ala Asn Phe Val Asp Gln Phe Gly Phe Asn Asp Glu
        195                 200                 205

Glu Phe Ala Asp Gln Asp Asp Asn Ile Asn Ala Pro Phe Asp Arg Ile
    210                 215                 220

Ala Glu Ile Asn Phe Asn Ile Asp Ala Asp Glu Asp Ser Pro Ser Ala
225                 230                 235                 240

Ala Leu Phe Glu Ala Cys Cys Ser Asp Arg Ile Gln Pro Phe Asp Asp
                245                 250                 255

Asp Glu Asp Glu Asp Ile Trp Glu Asp Ser Asp Thr Arg Cys Ala Ala
            260                 265                 270

Arg Val Met Ala Arg Pro Arg Phe Gly Ala Pro His Ala Ser Glu Ser
        275                 280                 285

Cys Ser Lys Asn Gly Pro Glu Arg Gly Gly Gln Asp Gly Lys Ala Ser
    290                 295                 300

Leu Glu Ala His Arg Asp Ala Pro Gly Ala Gly Ala Pro Pro Ala Pro
305                 310                 315                 320

Gly Lys Lys Glu Ala Pro Pro Val Glu Gly Asp Ser Glu Gly Ala Met
                325                 330                 335

Trp Thr Ala Val Phe Asp Glu Pro Ala Asn Ser Thr Pro Thr Ala Pro
            340                 345                 350

Gly Val Val Xaa Asp Val Gly Ser Ser Val Trp Ala Ala Gly Thr Ser
        355                 360                 365

Ala Pro Glu Glu Lys Gly Trp Ala Lys Phe Thr Asp Phe Gln Pro Phe
    370                 375                 380

Cys Cys Ser Glu Ser Gly Pro Arg Cys Ser Ser Pro Val Asp Thr Glu
385                 390                 395                 400

Cys Ser His Ala Glu Gly Ser Arg Ser Gln Gly Pro Glu Lys Ala Phe
                405                 410                 415

Ser Pro Ala Ser Pro Cys Ala Trp Asn Val Cys Val Thr Arg Lys Ala
            420                 425                 430

Pro Leu Leu Ala Ser Asp Ser Ser Ser Ser Gly Gly Ser His Ser Glu
        435                 440                 445

Asp Gly Asp Gln Lys Ala Ala Ser Ala Met Asp Ala Val Ser Arg Gly
    450                 455                 460

Pro Gly Arg Glu Ala Pro Pro Leu Pro Thr Val Ala Arg Thr Glu Glu
465                 470                 475                 480

Ala Val Gly Arg Val Gly Cys Ala Asp Ser Arg Leu Leu Ser Pro Ala
                485                 490                 495

Cys Pro Ala Pro Lys Glu Val Thr Ala Ala Pro Ala Val Ala Val Pro
            500                 505                 510

Pro Glu Ala Thr Val Ala Ile Thr Thr Ala Leu Ser Lys Ala Gly Pro
        515                 520                 525

Ala Ile Pro Thr Pro Ala Val Ser Ser Ala Leu Ala Val Ala Val Pro
    530                 535                 540

Leu Gly Pro Ile Met Ala Val Thr Ala Ala Pro Ala Met Val Ala Thr
545                 550                 555                 560

Leu Gly Thr Val Thr Lys Asp Gly Lys Thr Asp Ala Pro Pro Glu Gly
                565                 570                 575

Ala Ala Leu Asn Gly Pro Val 
            580



<210> 2526
<211> 299
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (213)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (215)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (282)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (285)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (296)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (297)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (299)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2526
Met Ala Ala Ser Gly Glu Pro Gln Arg Gln Trp Gln Glu Glu Val Ala
  1               5                  10                  15

Ala Val Val Val Val Gly Ser Cys Met Thr Asp Leu Val Ser Leu Thr
             20                  25                  30

Ser Arg Leu Pro Lys Thr Gly Glu Thr Ile His Gly His Lys Phe Phe
         35                  40                  45

Ile Gly Phe Gly Gly Lys Gly Ala Asn Gln Cys Val Gln Ala Ala Arg
     50                  55                  60

Leu Gly Ala Met Thr Ser Met Val Cys Lys Val Gly Lys Asp Ser Phe
 65                  70                  75                  80

Gly Asn Asp Tyr Ile Glu Asn Leu Lys Gln Asn Asp Ile Ser Thr Glu
                 85                  90                  95

Phe Thr Tyr Gln Thr Lys Asp Ala Ala Thr Gly Thr Ala Ser Ile Ile
            100                 105                 110

Val Asn Asn Glu Gly Gln Asn Ile Ile Val Ile Val Ala Gly Ala Asn
        115                 120                 125

Leu Leu Leu Asn Thr Glu Asp Leu Arg Ala Ala Ala Asn Val Ile Ser
    130                 135                 140

Arg Ala Lys Val Met Val Cys Gln Leu Glu Ile Thr Pro Ala Thr Ser
145                 150                 155                 160

Leu Glu Ala Leu Thr Met Ala Arg Arg Ser Gly Val Lys Thr Leu Phe
                165                 170                 175

Asn Pro Ala Pro Ala Ile Ala Asp Leu Asp Pro Gln Phe Tyr Thr Leu
            180                 185                 190

Ser Asp Val Phe Cys Cys Asn Glu Ser Glu Ala Glu Ile Leu Thr Gly
        195                 200                 205

Leu Thr Val Gly Xaa Ala Xaa Asp Ala Gly Glu Ala Ala Leu Val Leu
    210                 215                 220

Leu Lys Arg Gly Cys Gln Val Val Ile Ile Thr Leu Gly Ala Glu Gly
225                 230                 235                 240

Cys Val Val Leu Ser Gln Thr Glu Pro Glu Pro Lys His Ile Pro Thr
                245                 250                 255

Glu Lys Val Lys Ala Val Asp Thr Thr Gly Ala Gly Asp Ser Phe Val
            260                 265                 270

Gly Thr Leu Ala Xaa Tyr Trp Leu Thr Xaa Gln Ile Xaa Leu Gly Arg
        275                 280                 285

His Ala His Arg Ser Asn Ser Xaa Xaa Ser Xaa 
    290                 295



<210> 2527
<211> 337
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2527
Met Glu Lys Ser Trp Met Leu Trp Xaa Phe Val Glu Arg Trp Leu Ile
  1               5                  10                  15

Ala Leu Ala Ser Trp Ser Trp Ala Leu Cys Arg Ile Ser Leu Leu Pro
             20                  25                  30

Leu Ile Val Thr Phe His Leu Tyr Gly Gly Ile Ile Leu Leu Leu Leu
         35                  40                  45

Ile Phe Ile Ser Ile Ala Gly Ile Leu Tyr Lys Phe Gln Asp Val Leu
     50                  55                  60

Leu Tyr Phe Pro Glu Gln Pro Ser Ser Ser Arg Leu Tyr Val Pro Met
 65                  70                  75                  80

Pro Thr Gly Ile Pro His Glu Asn Ile Phe Ile Arg Thr Lys Asp Gly
                 85                  90                  95

Ile Arg Leu Asn Leu Ile Leu Ile Arg Tyr Thr Gly Asp Asn Ser Pro
            100                 105                 110

Tyr Ser Pro Thr Ile Ile Tyr Phe His Gly Asn Ala Gly Asn Ile Gly
        115                 120                 125

His Arg Leu Pro Asn Ala Leu Leu Met Leu Val Asn Leu Lys Val Asn
    130                 135                 140

Leu Leu Leu Val Asp Tyr Arg Gly Tyr Gly Lys Ser Glu Gly Glu Ala
145                 150                 155                 160

Ser Glu Glu Gly Leu Tyr Leu Asp Ser Glu Ala Val Leu Asp Tyr Val
                165                 170                 175

Met Thr Arg Pro Asp Leu Asp Lys Thr Lys Ile Phe Leu Phe Gly Arg
            180                 185                 190

Ser Leu Gly Gly Ala Val Ala Ile His Leu Ala Ser Glu Asn Ser His
        195                 200                 205

Arg Ile Ser Ala Ile Met Val Glu Asn Thr Phe Leu Ser Ile Pro His
    210                 215                 220

Met Ala Ser Thr Leu Phe Ser Phe Phe Pro Met Arg Tyr Leu Pro Leu
225                 230                 235                 240

Trp Cys Tyr Lys Asn Lys Phe Leu Ser Tyr Arg Lys Ile Ser Gln Cys
                245                 250                 255

Arg Met Pro Ser Leu Phe Ile Ser Gly Leu Ser Asp Gln Leu Ile Pro
            260                 265                 270

Pro Val Met Met Lys Gln Leu Tyr Glu Leu Ser Pro Ser Arg Thr Lys
        275                 280                 285

Arg Leu Ala Ile Phe Pro Asp Gly Thr His Asn Asp Thr Trp Gln Cys
    290                 295                 300

Gln Gly Tyr Phe Thr Ala Leu Glu Gln Phe Ile Lys Glu Val Val Lys
305                 310                 315                 320

Ser His Ser Pro Glu Glu Met Ala Lys Thr Ser Ser Asn Val Thr Ile
                325                 330                 335

Ile 




<210> 2528
<211> 204
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (194)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (200)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2528
Met Lys His Leu Gly Tyr Leu Gly Tyr Thr Ser Gly Leu Ser Leu Thr
  1               5                  10                  15

Cys Met Leu Phe Phe Leu Val Ser Val Ile Tyr Lys Lys Phe Gln Leu
             20                  25                  30

Gly Cys Ala Ile Gly His Asn Glu Thr Ala Met Glu Ser Glu Ala Leu
         35                  40                  45

Val Gly Leu Pro Ser Gln Gly Leu Asn Ser Ser Cys Glu Ala Gln Met
     50                  55                  60

Phe Thr Val Asp Ser Gln Met Ser Tyr Thr Val Pro Ile Met Ala Phe
 65                  70                  75                  80

Ala Phe Val Cys His Pro Glu Val Leu Pro Ile Tyr Thr Glu Leu Cys
                 85                  90                  95

Arg Ser Thr Thr Ser Thr Pro Gln Ala Leu Gln Ala Gln Asp Ala Gly
            100                 105                 110

Arg Gly Gln Arg Val His Trp Gly His Val Leu His Val Trp Ala His
        115                 120                 125

Ser Asn Leu Trp Ile Pro His Leu Leu Gln Gln Cys Glu Gly Gly Asp
    130                 135                 140

Ala Ala His Val Gln Pro Glu Gly Pro Ala His Pro Leu Cys Ala Pro
145                 150                 155                 160

Gly Arg Ala Ala Ser Xaa Val Thr Pro His Cys Ala Ser Arg Ala Gly
                165                 170                 175

Ser Tyr Pro Pro Gly Pro Gly Ser Asn Cys Phe Ser Gln Ala Arg Ala
            180                 185                 190

Phe Xaa Leu Ala Thr Thr Leu Xaa Ala Ile Ser Xaa 
        195                 200



<210> 2529
<211> 101
<212> PRT
<213> Homo sapiens

<400> 2529
Met Cys Ile Cys Ile Tyr His Ala Ala Gly Val Ser Phe Met Leu Leu
  1               5                  10                  15

Ser Pro Gly Glu Val Thr Ser Thr Ile Lys Gly Gly Ser Glu Met Ala
             20                  25                  30

Ser Gly Phe Leu Gly Val Gly Gln Gly Pro Ala Gly Gly Phe Pro Ser
         35                  40                  45

Arg Cys Thr Glu Gly Ser Ala Glu Pro Thr Val Cys Arg Gly Cys Val
     50                  55                  60

Pro Arg Ala Leu Pro Arg Pro Pro Pro Ala Leu Ala Ser Ala Leu Gln
 65                  70                  75                  80

Gly Gly Val Pro Ile Leu Gly Ala Val Cys His Ala His Leu Thr Gln
                 85                  90                  95

Val Cys Val Pro Val 
            100



<210> 2530
<211> 207
<212> PRT
<213> Homo sapiens

<400> 2530
Met Trp Lys Pro Ser Pro Ser Ser Ser Pro Ala Ser Trp Ser Cys Thr
  1               5                  10                  15

Ala Leu Arg Ala Pro Gln Ser Cys Leu Arg Ala Ala Thr Val Arg Pro
             20                  25                  30

Val Thr Leu Gln Ala Arg Ala Asp Ser Pro Thr Val Pro Glu Pro Val
         35                  40                  45

His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val
     50                  55                  60

His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val
 65                  70                  75                  80

His Arg Pro Gln Asp Pro Trp His Ile Pro Gly Val Pro Glu Pro Val
                 85                  90                  95

His Arg Pro Gln Asp Pro Trp Pro Trp Leu Gln Leu Val Pro Pro Ala
            100                 105                 110

Glu Leu Ala Tyr Cys Leu Leu Met Leu Leu Leu Ala His Cys Met Lys
        115                 120                 125

Gln Gln Ala Arg Pro Gly His Pro Asp Phe Leu His Arg Glu Ala Trp
    130                 135                 140

Ala Cys Leu Ser Ala Ala Gly Gly Leu Ala Ser Pro Gly Leu Leu Leu
145                 150                 155                 160

Trp Ala Thr Ala Arg Pro Arg Ala Ser Gly Glu Ala Gly Pro Gly Arg
                165                 170                 175

Ala Leu Val Gly Ala Asp Ala Ala Cys Cys Pro Arg His Ser Val Leu
            180                 185                 190

Ser Leu Val Asp Ile Pro Ser Gly Gln Val Leu Pro Gln Gly Gln 
        195                 200                 205



<210> 2531
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2531
Met Val Lys Glu Phe Gly Leu Met Val Phe Met Ala Gly Val Gly Leu
  1               5                  10                  15

Ser Ala Gly Ser Gly Ile Asn Asn Gly Leu Gly Ala Ile Gly Gly Gln
             20                  25                  30

Met Leu Ile Ala Gly Leu Ile Val Ser Leu Val Pro Val Val Ile Cys
         35                  40                  45

Phe Leu Phe Gly Ala Tyr Val Leu Arg Met Asn Arg Ala Leu Leu Phe
     50                  55                  60

Gly Ala Met Met Gly Ala Arg Xaa Xaa Ala Pro Ala Met Glu Ile Ile
 65                  70                  75                  80

Ser Asp Thr Ala Arg Ser Asn Ile Pro Ala Leu Gly Tyr Ala Gly Thr
                 85                  90                  95

Tyr Ala Ile Ala Asn Val Leu Leu Thr Leu Ala Gly Thr Ile Ile Val
            100                 105                 110

Met Val Trp Pro Gly Leu Gly 
        115



<210> 2532
<211> 162
<212> PRT
<213> Homo sapiens

<400> 2532
Met Ser Ser Ser Leu Leu Pro Ser Cys Lys Ser Ile Arg Ser Tyr Asp
  1               5                  10                  15

Arg Glu Phe Leu Phe Val Asp Ala Asn Trp Gly Asn Leu Arg Glu Tyr
             20                  25                  30

Trp Gly His Gly Ser Phe Pro Cys Phe Ser Phe Cys Ser Leu Leu Cys
         35                  40                  45

Phe Gln Val Leu Ser Cys Ser Phe Leu Phe Leu Cys Arg Thr Gly Lys
     50                  55                  60

Ala Trp Glu Glu Asp Phe Asp Lys Phe Leu Val Leu Cys Val Val Met
 65                  70                  75                  80

Gly Trp Ser Glu Gly Gln Val Asn Lys Pro Thr Phe Gly Tyr Tyr Pro
                 85                  90                  95

Gly Lys Leu Arg Val Asp Gly Arg Val Met Ile Val Ala Cys Val Phe
            100                 105                 110

Ala Ile Phe Leu Cys Gln Cys Gly Phe Leu Ser Ser Ser Phe Phe Ser
        115                 120                 125

Ser Glu Gly Ser Ala Thr Val Ser Ile Pro Trp Phe Leu Gln Lys Thr
    130                 135                 140

Ala Lys Cys Ala Leu Arg Ala Ser Gly Asp Val Leu Cys Cys Ser Pro
145                 150                 155                 160

Ser Ser 




<210> 2533
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2533
Met Ser Glu Pro Asp Thr Ser Ser Gly Phe Ser Gly Ser Val Glu Asn
  1               5                  10                  15

Gly Thr Phe Leu Glu Leu Phe Pro Thr Ser Leu Ser Thr Ser Val Asp
             20                  25                  30

Pro Ser Ser Gly His Leu Ser Asn Val Tyr Ile Tyr Val Ser Ile Phe
         35                  40                  45

Leu Ser Leu Leu Ala Phe Leu Leu Leu Leu Leu Ile Ile Ala Leu Gln
     50                  55                  60

Arg Leu Lys Asn Ile Ile Ser Ser Ser Ser Ser Tyr Pro Glu Tyr Pro
 65                  70                  75                  80

Ser Asp Ala Gly Ser Ser Phe Thr Asn Leu Glu Val Cys Ser Ile Ser
                 85                  90                  95

Ser Gln Arg Ser Thr Phe Ser Asn Leu Ser Ser 
            100                 105



<210> 2534
<211> 157
<212> PRT
<213> Homo sapiens

<400> 2534
Met Ala Leu Leu Arg Lys Ile Asn Gln Val Leu Leu Phe Leu Leu Ile
  1               5                  10                  15

Val Thr Leu Cys Val Ile Leu Tyr Lys Lys Val His Lys Gly Thr Val
             20                  25                  30

Pro Lys Asn Asp Ala Asp Asp Glu Ser Glu Thr Pro Glu Glu Leu Glu
         35                  40                  45

Glu Glu Ile Pro Val Val Ile Cys Ala Ala Ala Gly Arg Met Gly Ala
     50                  55                  60

Thr Met Ala Ala Ile Asn Ser Ile Tyr Ser Asn Thr Asp Ala Asn Ile
 65                  70                  75                  80

Leu Phe Tyr Val Val Gly Leu Arg Asn Thr Leu Thr Arg Ile Arg Lys
                 85                  90                  95

Trp Ile Glu His Ser Lys Leu Arg Glu Ile Asn Phe Lys Ile Val Glu
            100                 105                 110

Phe Asn Pro Met Val Leu Lys Gly Lys Ile Arg Pro Asp Ser Ser Arg
        115                 120                 125

Pro Glu Leu Leu Gln Pro Leu Asn Phe Val Arg Phe Tyr Leu Pro Leu
    130                 135                 140

Leu Ile His Gln His Glu Glu Ser His Leu Phe Gly Arg 
145                 150                 155



<210> 2535
<211> 346
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (243)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (262)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (269)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (289)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (342)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (344)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2535
Met Thr Ser Ser Val Gln Val Tyr Asn Leu Ser Gln Asn Ile Gln Glu
  1               5                  10                  15

Asp Asp Leu Gln His Leu Gln Leu Phe Thr Glu Tyr Gly Arg Leu Ala
             20                  25                  30

Met Glu Glu Ile Tyr Gln Lys Pro Phe Gln Thr Leu Met Phe Leu Ile
         35                  40                  45

Arg Asp Trp Ser Tyr Pro Tyr Xaa His Ser Tyr Gly Leu Glu Gly Gly
     50                  55                  60

Lys Gln Phe Leu Glu Lys Arg Leu Gln Val Lys Gln Asn Gln His Glu
 65                  70                  75                  80

Glu Leu Gln Asn Val Arg Lys His Ile His Asn Cys Phe Ser Asn Leu
                 85                  90                  95

Gly Cys Phe Leu Leu Pro His Pro Gly Leu Lys Val Ala Thr Asn Pro
            100                 105                 110

Ser Phe Asp Gly Arg Leu Lys Asp Ile Asp Glu Asp Phe Lys Arg Glu
        115                 120                 125

Leu Arg Asn Leu Val Pro Leu Leu Leu Ala Pro Glu Asn Leu Val Glu
    130                 135                 140

Lys Glu Ile Ser Gly Ser Lys Val Thr Cys Arg Asp Leu Val Glu Tyr
145                 150                 155                 160

Phe Lys Ala Tyr Ile Lys Ile Tyr Gln Gly Glu Glu Leu Pro His Pro
                165                 170                 175

Lys Ser Met Leu Gln Ala Thr Ala Glu Ala Asn Asn Leu Ala Ala Val
            180                 185                 190

Ala Gly Ala Arg Asp Thr Tyr Cys Lys Ser Met Glu Gln Val Cys Gly
        195                 200                 205

Gly Asp Lys Pro Tyr Ile Ala Pro Ser Asp Leu Glu Arg Lys His Leu
    210                 215                 220

Asp Leu Lys Glu Val Ala Ile Lys Gln Phe Arg Ser Val Lys Lys Met
225                 230                 235                 240

Gly Gly Xaa Glu Phe Cys Arg Arg Tyr Gln Asp Gln Leu Glu Ala Glu
                245                 250                 255

Ile Glu Glu Thr Tyr Xaa Asn Phe Ile Lys His Asn Xaa Gly Lys Asn
            260                 265                 270

Ile Phe Tyr Ala Ala Arg Thr Pro Ala Thr Leu Phe Ala Val Met Phe
        275                 280                 285

Xaa Met Tyr Ile Ile Ser Gly Leu Thr Gly Phe Ile Gly Leu Asn Ser
    290                 295                 300

Ile Ala Val Leu Cys Asn Leu Val Met Gly Leu Ala Leu Ile Phe Leu
305                 310                 315                 320

Cys Thr Trp Ala Tyr Val Lys Tyr Ser Gly Glu Phe Arg Glu Ile Gly
                325                 330                 335

Thr Val Ile Asp Pro Xaa Cys Xaa Lys Thr 
            340                 345



<210> 2536
<211> 100
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2536
Met Gln Ile Gly Tyr Leu Tyr Ser Val Ser Phe Asn Phe Met Phe Ile
  1               5                  10                  15

His Ser Phe Ser Asn Val Tyr Pro Ser Ile Gln Thr Ser Pro Asn Pro
             20                  25                  30

Ser Lys Leu Thr Gln Ile Leu Pro Ile Ser Glu Ser Phe Leu Ala His
         35                  40                  45

His Ser Ile Ala Pro Ile Cys Ala Phe Xaa Phe Arg Asn His Ile Leu
     50                  55                  60

Leu Cys His Ala Ser Val Leu Ser Leu Ala Ser Ile Ser Phe Trp Thr
 65                  70                  75                  80

Gln Asn Pro Cys Pro Lys His Leu Cys Ile Pro Lys Ala Thr Arg Ile
                 85                  90                  95

Ala Pro Cys Lys 
            100



<210> 2537
<211> 151
<212> PRT
<213> Homo sapiens

<400> 2537
Met Leu Leu Phe Asn Trp Ile Cys Ile Val Ile Thr Gly Leu Ala Met
  1               5                  10                  15

Asp Met Gln Leu Leu Met Ile Pro Leu Ile Met Ser Val Leu Tyr Val
             20                  25                  30

Trp Ala Gln Leu Asn Arg Asp Met Ile Val Ser Phe Trp Phe Gly Thr
         35                  40                  45

Arg Phe Lys Ala Cys Tyr Leu Pro Trp Val Ile Leu Gly Phe Asn Tyr
     50                  55                  60

Ile Ile Gly Gly Ser Val Ile Asn Glu Leu Ile Gly Asn Leu Val Gly
 65                  70                  75                  80

His Leu Tyr Phe Phe Leu Met Phe Arg Tyr Pro Met Asp Leu Gly Gly
                 85                  90                  95

Arg Asn Phe Leu Ser Thr Pro Gln Phe Leu Tyr Arg Trp Leu Pro Ser
            100                 105                 110

Arg Arg Gly Gly Val Ser Gly Phe Gly Val Pro Pro Ala Ser Met Arg
        115                 120                 125

Arg Ala Ala Asp Gln Asn Gly Gly Gly Gly Arg His Asn Trp Gly Gln
    130                 135                 140

Gly Phe Arg Leu Gly Asp Gln 
145                 150



<210> 2538
<211> 129
<212> PRT
<213> Homo sapiens

<400> 2538
Met Asp Phe Gly Ile Trp Lys Gly His Leu Asp Ala Leu Thr Ala Asp
  1               5                  10                  15

Val Lys Glu Lys Met Tyr Asn Val Leu Leu Phe Val Asp Gly Gly Trp
             20                  25                  30

Met Val Asp Val Arg Glu Asp Ala Lys Glu Asp His Glu Arg Thr His
         35                  40                  45

Gln Met Val Leu Leu Arg Lys Leu Cys Leu Pro Met Leu Cys Phe Leu
     50                  55                  60

Leu His Thr Ile Leu His Ser Thr Gly Gln Tyr Gln Glu Cys Leu Gln
 65                  70                  75                  80

Leu Ala Asp Met Val Ser Ser Glu Arg His Lys Leu Tyr Leu Val Phe
                 85                  90                  95

Ser Lys Glu Glu Leu Arg Lys Leu Leu Gln Lys Leu Arg Glu Ser Ser
            100                 105                 110

Leu Met Leu Leu Asp Gln Gly Leu Asp Pro Leu Gly Tyr Glu Ile Gln
        115                 120                 125

Leu 




<210> 2539
<211> 292
<212> PRT
<213> Homo sapiens

<400> 2539
Met Gln Ile Leu Leu Tyr Ser Gln Asp Tyr Gln Arg Leu Met Thr Val
  1               5                  10                  15

Ala Glu Gly Ile Thr Thr Leu Leu Phe Pro Phe Gln Trp Gln His Val
             20                  25                  30

Tyr Val Pro Ile Leu Pro Ala Ser Leu Leu His Phe Leu Asp Ala Pro
         35                  40                  45

Val Pro Tyr Leu Met Gly Leu Gln Ser Lys Glu Gly Thr Asp Arg Ser
     50                  55                  60

Lys Leu Glu Leu Pro Gln Glu Ala Asn Leu Cys Phe Val Asp Ile Asp
 65                  70                  75                  80

Asn His Phe Ile Glu Leu Pro Glu Glu Phe Pro Gln Phe Pro Asn Lys
                 85                  90                  95

Val Asp Phe Ile Gln Glu Leu Ser Glu Val Leu Val Gln Phe Gly Ile
            100                 105                 110

Pro Pro Glu Gly Ser Leu His Cys Ser Glu Ser Thr Ser Lys Leu Lys
        115                 120                 125

Asn Met Val Leu Lys Asp Leu Val Asn Asp Lys Lys Asn Gly Asn Val
    130                 135                 140

Cys Thr Asn Asn Ile Ser Met Tyr Glu Leu Leu Lys Gly Asn Glu Thr
145                 150                 155                 160

Ile Ala Arg Leu Gln Ala Leu Ala Lys Arg Thr Gly Val Ala Val Glu
                165                 170                 175

Lys Met Asp Leu Ser Ala Ser Leu Gly Glu Lys Asp Lys Asp Leu Lys
            180                 185                 190

Leu His Cys Glu Glu Ala Glu Leu Arg Asp Tyr Gln Leu Asn Val Gln
        195                 200                 205

Leu Arg Glu Val Phe Ala Asn Arg Phe Thr Gln Met Phe Ala Asp Tyr
    210                 215                 220

Glu Ala Phe Val Ile Gln Thr Ala Gln Asp Met Glu Ser Trp Leu Thr
225                 230                 235                 240

Asn Arg Glu Gln Met Gln Asn Phe Asp Lys Val Lys Arg Thr Ile Val
                245                 250                 255

Phe Leu Leu Trp Leu Leu Val Ala Leu Leu Leu Ile Leu Thr Phe Leu
            260                 265                 270

Asn Phe Leu Phe Phe Cys Ala Tyr Ala Tyr Pro Tyr Ile Ile Asp Phe
        275                 280                 285

Val Asn Leu Phe 
    290



<210> 2540
<211> 260
<212> PRT
<213> Homo sapiens

<400> 2540
Met Asp Pro Gly Asp Asp Trp Leu Val Glu Ser Leu Arg Leu Tyr Gln
  1               5                  10                  15

Asp Phe Tyr Ala Phe Asp Leu Ser Gly Ala Thr Arg Val Leu Glu Trp
             20                  25                  30

Ile Asp Asp Lys Gly Val Phe Val Ala Gly Tyr Glu Ser Leu Lys Lys
         35                  40                  45

Asn Glu Ile Leu His Leu Lys Leu Pro Leu Arg Leu Ser Val Lys Glu
     50                  55                  60

Asn Lys Gly Leu Phe Pro Glu Arg Asp Phe Lys Val Arg His Gly Gly
 65                  70                  75                  80

Phe Ser Asp Arg Ser Ile Phe Asp Leu Lys His Val Pro His Thr Arg
                 85                  90                  95

Leu Leu Val Thr Ser Gly Leu Pro Gly Cys Tyr Leu Gln Val Trp Gln
            100                 105                 110

Val Ala Glu Asp Ser Asp Val Ile Lys Ala Val Ser Thr Ile Ala Val
        115                 120                 125

His Glu Lys Glu Glu Ser Leu Trp Pro Arg Val Ala Val Phe Ser Thr
    130                 135                 140

Leu Ala Pro Gly Val Leu His Gly Ala Arg Leu Arg Ser Leu Gln Val
145                 150                 155                 160

Val Asp Leu Glu Ser Arg Lys Thr Thr Tyr Thr Ser Asp Val Ser Asp
                165                 170                 175

Ser Glu Glu Leu Ser Ser Leu Gln Val Leu Asp Ala Asp Thr Phe Ala
            180                 185                 190

Phe Cys Cys Ala Ser Gly Arg Leu Gly Leu Val Asp Thr Arg Gln Lys
        195                 200                 205

Trp Ala Pro Leu Glu Asn Arg Ser Pro Gly Pro Gly Ser Gly Gly Glu
    210                 215                 220

Arg Trp Cys Ala Glu Val Gly Ser Trp Gly Gln Gly Trp Gly Ser Ile
225                 230                 235                 240

Ala Ser Leu Ala Gln Met Gly Val Phe Val Phe Leu Thr Pro Gly Ile
                245                 250                 255

Ser Ala Ile Leu 
            260



<210> 2541
<211> 232
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (27)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (33)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2541
Met Glu Asn Thr Asn Met Pro Glu Gly Thr Ile Ser Glu Asn Thr Asn
  1               5                  10                  15

Tyr Asn His Xaa Xaa Glu Ala Asp Ser Xaa Xaa Thr Ala Phe Asn Leu
             20                  25                  30

Xaa Pro Thr Val Lys Gln Thr Glu Thr Lys Trp Glu Tyr Asn Asn Val
         35                  40                  45

Gly Thr Asp Leu Ser Pro Glu Pro Lys Ser Phe Asn Tyr Pro Leu Leu
     50                  55                  60

Ser Ser Pro Gly Asp Gln Phe Glu Ile Gln Leu Thr Gln Gln Leu Gln
 65                  70                  75                  80

Ser Xaa Ile Pro Asn Asn Asn Val Arg Arg Leu Ile Ala His Val Ile
                 85                  90                  95

Arg Thr Leu Lys Met Asp Cys Ser Gly Ala His Val Gln Val Thr Cys
            100                 105                 110

Ala Lys Leu Val Ser Arg Thr Gly His Leu Met Lys Leu Leu Ser Gly
        115                 120                 125

Gln Gln Glu Val Lys Ala Ser Lys Ile Glu Trp Asp Thr Asp Gln Trp
    130                 135                 140

Lys Thr Glu Asn Tyr Ile Asn Glu Ser Thr Glu Ala Gln Ser Glu Gln
145                 150                 155                 160

Lys Glu Lys Ser Leu Glu Phe Thr Lys Glu Leu Pro Gly Tyr Gly Tyr
                165                 170                 175

Thr Lys Lys Leu Ile Leu Ala Leu Ile Val Thr Gly Ile Leu Thr Ile
            180                 185                 190

Leu Ile Ile Leu Leu Cys Leu Ile Glu Ile Cys Cys His Arg Arg Ser
        195                 200                 205

Leu Gln Glu Asp Glu Glu Gly Phe Ser Arg Asp Ser Glu Ala Pro Thr
    210                 215                 220

Glu Glu Glu Ser Glu Ala Leu Pro 
225                 230



<210> 2542
<211> 175
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (145)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2542
Met Trp Trp Asp His Gly Val Tyr Tyr Cys Thr Ile Glu Ala Pro Gly
  1               5                  10                  15

Asp Thr Ser Gly Asp Pro Asp Lys Glu Val Lys Leu Ile Val Leu His
             20                  25                  30

Trp Leu Thr Val Ile Phe Ile Ile Leu Gly Ala Leu Leu Leu Leu Leu
         35                  40                  45

Leu Ile Gly Val Cys Trp Cys Gln Cys Cys Pro Gln Tyr Cys Cys Cys
     50                  55                  60

Tyr Ile Arg Cys Pro Cys Cys Pro Ala His Cys Cys Cys Pro Glu Glu
 65                  70                  75                  80

Ala Leu Ala Arg His Arg Tyr Met Lys Gln Ala Gln Ala Leu Gly Pro
                 85                  90                  95

Gln Met Met Gly Lys Pro Leu Tyr Trp Gly Ala Asp Arg Ser Ser Gln
            100                 105                 110

Xaa Ser Ser Tyr Pro Met His Pro Leu Leu Gln Arg Asp Leu Ser Leu
        115                 120                 125

Pro Ser Ser Leu Pro Gln Met Pro Met Thr Gln Thr Thr Asn Xaa Pro
    130                 135                 140

Xaa Ile Ala Asn Gly Val Leu Glu Tyr Leu Glu Lys Glu Leu Arg Asn
145                 150                 155                 160

Leu Asn Leu Ala Gln Pro Leu Pro Pro Asp Leu Lys Gly Arg Phe 
                165                 170                 175



<210> 2543
<211> 394
<212> PRT
<213> Homo sapiens

<400> 2543
Met Leu Ser Ser Phe Asn Glu Trp Phe Trp Gln Asp Arg Phe Trp Leu
  1               5                  10                  15

Pro Pro Asn Val Thr Trp Thr Glu Leu Glu Asp Arg Asp Gly Arg Val
             20                  25                  30

Tyr Pro His Pro Gln Asp Leu Leu Ala Ala Leu Pro Leu Ala Leu Val
         35                  40                  45

Leu Leu Ala Met Arg Leu Ala Phe Glu Arg Phe Ile Gly Leu Pro Leu
     50                  55                  60

Ser Arg Trp Leu Gly Val Arg Asp Gln Thr Arg Arg Gln Val Lys Pro
 65                  70                  75                  80

Asn Ala Thr Leu Glu Lys His Phe Leu Thr Glu Gly His Arg Pro Lys
                 85                  90                  95

Glu Pro Gln Leu Ser Leu Leu Ala Ala Gln Cys Gly Leu Thr Leu Gln
            100                 105                 110

Gln Thr Gln Arg Trp Phe Arg Arg Arg Arg Asn Gln Asp Arg Pro Gln
        115                 120                 125

Leu Thr Lys Lys Phe Cys Glu Ala Ser Trp Arg Phe Leu Phe Tyr Leu
    130                 135                 140

Ser Ser Phe Val Gly Gly Leu Ser Val Leu Tyr His Glu Ser Trp Leu
145                 150                 155                 160

Trp Ala Pro Val Met Cys Trp Asp Arg Tyr Pro Asn Gln Thr Leu Lys
                165                 170                 175

Pro Ser Leu Tyr Trp Trp Tyr Leu Leu Glu Leu Gly Phe Tyr Leu Ser
            180                 185                 190

Leu Leu Ile Arg Leu Pro Phe Asp Val Lys Arg Lys Asp Phe Lys Glu
        195                 200                 205

Gln Val Ile His His Phe Val Ala Val Ile Leu Met Thr Phe Ser Tyr
    210                 215                 220

Ser Ala Asn Leu Leu Arg Ile Gly Ser Leu Val Leu Leu Leu His Asp
225                 230                 235                 240

Ser Ser Asp Tyr Leu Leu Glu Ala Cys Lys Met Val Asn Tyr Met Gln
                245                 250                 255

Tyr Gln Gln Val Cys Asp Ala Leu Phe Leu Ile Phe Ser Phe Val Phe
            260                 265                 270

Phe Tyr Thr Arg Leu Val Leu Phe Pro Thr Gln Ile Leu Tyr Thr Thr
        275                 280                 285

Tyr Tyr Glu Ser Ile Ser Asn Arg Gly Pro Phe Phe Gly Tyr Tyr Phe
    290                 295                 300

Phe Asn Gly Leu Leu Met Leu Leu Gln Leu Leu His Val Phe Trp Ser
305                 310                 315                 320

Cys Leu Ile Leu Arg Met Leu Tyr Ser Phe Met Lys Lys Gly Gln Met
                325                 330                 335

Glu Lys Asp Ile Arg Ser Asp Val Glu Glu Ser Asp Ser Ser Glu Glu
            340                 345                 350

Ala Ala Ala Ala Gln Glu Pro Leu Gln Leu Lys Asn Gly Thr Ala Gly
        355                 360                 365

Gly Pro Arg Pro Ala Pro Thr Asp Gly Pro Arg Ser Arg Val Ala Gly
    370                 375                 380

Arg Leu Thr Asn Arg His Thr Thr Ala Thr 
385                 390



<210> 2544
<211> 452
<212> PRT
<213> Homo sapiens

<400> 2544
Met Leu Thr Thr Phe Gly Thr Ala Thr Tyr Lys Val Gly Leu Lys Val
  1               5                  10                  15

His Pro Asn Glu Glu Asp Pro Arg Val Pro Ile Met Cys Trp Gly Ser
             20                  25                  30

Cys Ala Tyr Thr Ile Gln Ser Ile Glu Arg Ile Leu Ser Asp Glu Asp
         35                  40                  45

Lys Pro Leu Phe Gly Pro Leu Pro Cys Arg Leu Asp Asp Cys Leu Arg
     50                  55                  60

Ser Leu Thr Arg Phe Ala Ala Ala His Trp Thr Val Ala Ser Val Ser
 65                  70                  75                  80

Val Val Gln Gly His Phe Cys Lys Leu Phe Ala Ser Leu Val Pro Asn
                 85                  90                  95

Asp Ser His Glu Glu Leu Pro Cys Ile Leu Asp Ile Asp Met Phe His
            100                 105                 110

Leu Leu Val Gly Leu Val Leu Ala Phe Pro Ala Leu Gln Cys Gln Asp
        115                 120                 125

Phe Ser Gly Ile Ser Leu Gly Thr Gly Asp Leu His Ile Phe His Leu
    130                 135                 140

Val Thr Met Ala His Ile Ile Gln Ile Leu Leu Thr Ser Cys Thr Glu
145                 150                 155                 160

Glu Asn Gly Met Asp Gln Glu Asn Pro Pro Cys Glu Glu Glu Ser Ala
                165                 170                 175

Val Leu Ala Leu Tyr Lys Thr Leu His Gln Tyr Thr Gly Ser Ala Leu
            180                 185                 190

Lys Glu Ile Pro Ser Gly Trp His Leu Trp Arg Ser Val Arg Ala Gly
        195                 200                 205

Ile Met Pro Phe Leu Lys Cys Ser Ala Leu Phe Phe His Tyr Leu Asn
    210                 215                 220

Gly Val Pro Ser Pro Pro Asp Ile Gln Val Pro Gly Thr Ser His Phe
225                 230                 235                 240

Glu His Leu Cys Ser Tyr Leu Ser Leu Pro Asn Asn Leu Ile Cys Leu
                245                 250                 255

Phe Gln Glu Asn Ser Glu Ile Met Asn Ser Leu Ile Glu Ser Trp Cys
            260                 265                 270

Arg Asn Ser Glu Val Lys Arg Tyr Leu Glu Gly Glu Arg Asp Ala Ile
        275                 280                 285

Arg Tyr Pro Arg Glu Ser Asn Lys Leu Ile Asn Leu Pro Glu Asp Tyr
    290                 295                 300

Ser Ser Leu Ile Asn Gln Ala Ser Asn Phe Ser Cys Pro Lys Ser Gly
305                 310                 315                 320

Gly Asp Lys Ser Arg Ala Pro Thr Leu Cys Leu Val Cys Gly Ser Leu
                325                 330                 335

Leu Cys Ser Gln Ser Tyr Cys Cys Gln Thr Glu Leu Glu Gly Glu Asp
            340                 345                 350

Val Gly Ala Cys Thr Ala His Thr Tyr Ser Cys Gly Ser Gly Val Gly
        355                 360                 365

Ile Phe Leu Arg Val Arg Glu Cys Gln Val Leu Phe Leu Ala Gly Lys
    370                 375                 380

Thr Lys Gly Cys Phe Tyr Ser Pro Pro Tyr Leu Asp Asp Tyr Gly Glu
385                 390                 395                 400

Thr Asp Gln Gly Leu Arg Arg Gly Asn Pro Leu His Leu Cys Lys Glu
                405                 410                 415

Arg Phe Lys Lys Ile Gln Lys Leu Trp His Gln His Ser Val Thr Glu
            420                 425                 430

Glu Ile Gly His Ala Gln Glu Ala Asn Gln Thr Leu Val Gly Ile Asp
        435                 440                 445

Trp Gln His Leu 
    450



<210> 2545
<211> 532
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (527)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (529)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2545
Met Ser Ala Phe Arg Ala Glu Phe Ile Ala Thr Arg Ser Met Asp Phe
  1               5                  10                  15

Ile Gly Met Ile Lys Glu Cys Asp Glu Ser Gly Phe Pro Lys His Leu
             20                  25                  30

Leu Phe Arg Ser Leu Gly Leu Asn Leu Ala Leu Ala Asp Pro Pro Glu
         35                  40                  45

Ser Asp Arg Leu Gln Ile Leu Asn Glu Ala Trp Lys Val Ile Thr Lys
     50                  55                  60

Leu Lys Asn Pro Gln Asp Tyr Ile Asn Cys Ala Glu Val Trp Val Glu
 65                  70                  75                  80

Tyr Thr Cys Lys His Phe Thr Lys Arg Glu Val Asn Thr Val Leu Ala
                 85                  90                  95

Asp Val Ile Lys His Met Thr Pro Asp Arg Ala Phe Glu Asp Ser Tyr
            100                 105                 110

Pro Gln Leu Gln Leu Ile Ile Lys Lys Val Ile Ala His Phe His Asp
        115                 120                 125

Phe Ser Val Leu Phe Ser Val Xaa Lys Phe Leu Pro Phe Leu Asp Met
    130                 135                 140

Phe Gln Lys Glu Ser Val Arg Val Glu Val Cys Lys Cys Ile Met Asp
145                 150                 155                 160

Ala Phe Ile Lys His Gln Gln Glu Pro Thr Lys Asp Pro Val Ile Leu
                165                 170                 175

Asn Ala Leu Leu His Val Cys Lys Thr Met His Asp Ser Val Asn Ala
            180                 185                 190

Leu Thr Leu Glu Asp Glu Lys Arg Met Leu Ser Tyr Leu Ile Asn Gly
        195                 200                 205

Phe Ile Lys Met Val Ser Phe Gly Arg Asp Phe Glu Gln Gln Leu Ser
    210                 215                 220

Phe Tyr Val Glu Ser Arg Ser Met Phe Cys Asn Leu Glu Pro Val Leu
225                 230                 235                 240

Val Gln Leu Ile His Ser Val Asn Arg Leu Ala Met Glu Thr Arg Lys
                245                 250                 255

Val Met Lys Gly Asn His Ser Arg Lys Thr Ala Ala Phe Val Arg Ala
            260                 265                 270

Cys Val Ala Tyr Cys Phe Ile Thr Ile Pro Ser Leu Ala Gly Ile Phe
        275                 280                 285

Thr Arg Leu Asn Leu Tyr Leu His Ser Gly Gln Val Ala Leu Ala Asn
    290                 295                 300

Gln Cys Leu Ser Gln Ala Asp Ala Phe Phe Lys Ala Ala Ile Ser Leu
305                 310                 315                 320

Val Pro Glu Val Pro Lys Met Ile Asn Ile Asp Gly Lys Met Arg Pro
                325                 330                 335

Ser Glu Ser Phe Leu Leu Glu Phe Leu Cys Asn Phe Phe Ser Thr Leu
            340                 345                 350

Leu Ile Val Pro Asp His Pro Glu His Gly Val Leu Phe Leu Val Arg
        355                 360                 365

Glu Leu Leu Asn Val Ile Gln Asp Tyr Thr Trp Glu Asp Asn Ser Asp
    370                 375                 380

Glu Lys Ile Arg Ile Tyr Thr Cys Val Leu His Leu Leu Ser Ala Met
385                 390                 395                 400

Ser Gln Glu Thr Tyr Leu Tyr His Ile Asp Lys Val Asp Ser Asn Asp
                405                 410                 415

Ser Leu Tyr Gly Gly Asp Ser Lys Phe Leu Ala Glu Asn Asn Lys Leu
            420                 425                 430

Cys Glu Thr Val Met Ala Gln Ile Leu Glu His Leu Lys Thr Leu Ala
        435                 440                 445

Lys Asp Glu Ala Leu Lys Arg Gln Ser Ser Leu Gly Leu Ser Phe Phe
    450                 455                 460

Asn Ser Ile Leu Ala His Gly Asp Leu Arg Asn Asn Lys Leu Asn Gln
465                 470                 475                 480

Leu Ser Val Asn Leu Trp His Leu Ala Gln Arg His Gly Cys Ala Asp
                485                 490                 495

Thr Arg Thr Met Val Lys Thr Leu Glu Tyr Ile Lys Lys Gln Ser Lys
            500                 505                 510

Gln Pro Asp Met Thr His Leu Thr Glu Leu Ala Leu Arg Leu Xaa Leu
        515                 520                 525

Xaa Thr Arg Thr 
    530



<210> 2546
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2546
Met Leu Phe Leu Gly Lys Val Leu Ile Val Cys Ser Thr Gly Leu Ala
  1               5                  10                  15

Gly Ile Met Leu Leu Asn Tyr Gln Gln Asp Tyr Thr Val Trp Val Leu
             20                  25                  30

Pro Leu Ile Ile Val Cys Leu Phe Ala Xaa Leu Val Ala His Cys Phe
         35                  40                  45

Leu Ser Ile Tyr Glu Met Val Val Asp Val Leu Phe Leu Cys Phe Ala
     50                  55                  60

Ile Asp Thr Lys Tyr Asn Asp Gly Ser Pro Gly Arg Glu Phe Tyr Met
 65                  70                  75                  80

Asp Lys Val Leu Met Glu Phe Val Glu Asn Ser Arg Lys Ala Met Lys
                 85                  90                  95

Glu Ala Gly Lys Gly Gly Val Ala Asp Ser Arg Glu Leu Lys Pro Met
            100                 105                 110

Leu Lys Lys Arg 
        115



<210> 2547
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (127)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2547
Met Thr Pro Thr Trp Thr Trp Arg Val Cys Gly Asp Gly Gly Ala Asp
  1               5                  10                  15

Arg Pro Pro Gln Pro Met Val Pro Leu Ala Val Glu Asn Gln Ala Gly
             20                  25                  30

Gly Glu Gly Ala Gly Gly Glu Leu Gly Ile Ser Leu Asn Met Cys Leu
         35                  40                  45

Leu Gly Ala Leu Val Leu Leu Gly Leu Gly Val Leu Leu Phe Ser Gly
     50                  55                  60

Gly Leu Ser Glu Ser Glu Thr Gly Pro Met Glu Glu Val Glu Arg Gln
 65                  70                  75                  80

Val Leu Pro Asp Pro Glu Val Leu Glu Ala Val Gly Asp Arg Gln Asp
                 85                  90                  95

Gly Leu Arg Glu Gln Leu Gln Ala Pro Xaa Pro Xaa Asp Lys Cys Pro
            100                 105                 110

Ser Leu Xaa Lys His Gly Ser Xaa Ala Gly Gln Ser Trp Pro Xaa Arg
        115                 120                 125

Thr Arg Thr 
    130



<210> 2548
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2548
Met Asp Asn Pro Thr Phe Ala Glu Asp Glu Glu Leu Gln Asn Met Asp
  1               5                  10                  15

Lys Glu Asp Ala Leu Ile Cys Phe Glu Glu His Ile Arg Ala Leu Glu
             20                  25                  30

Lys Glu Glu Glu Glu Glu Lys Gln Lys Ser Leu Leu Arg Glu Arg Arg
         35                  40                  45

Arg Gln Arg Lys Asn Arg Glu Ser Phe Gln Ile Phe Leu Asp Glu Leu
     50                  55                  60

His Glu His Gly Gln Leu His Ser Met Ser Ser Trp Met Glu Leu Tyr
 65                  70                  75                  80

Pro Thr Ile Ser Ser Asp Ile Arg Ser Leu Ile Cys Leu Val Ser Leu
                 85                  90                  95

Xaa Gln Leu His Leu Ile Phe Ser Ser Phe Met Leu Arg Asp Leu Lys
            100                 105                 110

Ala Arg Tyr Pro 
        115



<210> 2549
<211> 321
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (253)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (282)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (295)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (319)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2549
Met Ala Ala Lys Asn Ile Leu Tyr Asp Trp Ala Ala Gly Lys Leu Tyr
  1               5                  10                  15

Gln Gly Gln Val Asp Phe Ala Phe Phe Met Pro Cys Gly Glu Leu Leu
             20                  25                  30

Glu Arg Pro Gly Thr Arg Ser Leu Ala Asp Leu Ile Leu Asp Gln Cys
         35                  40                  45

Pro Asp Arg Gly Ala Pro Val Pro Gln Met Leu Ala Gln Pro Gln Arg
     50                  55                  60

Leu Leu Phe Ile Leu Asp Gly Ala Asp Glu Leu Pro Ala Leu Gly Gly
 65                  70                  75                  80

Pro Glu Ala Ala Pro Cys Thr Asp Pro Phe Glu Ala Ala Ser Gly Ala
                 85                  90                  95

Arg Val Leu Gly Gly Leu Leu Ser Lys Ala Leu Leu Pro Thr Ala Leu
            100                 105                 110

Leu Leu Val Thr Thr Arg Ala Ala Ala Pro Gly Arg Leu Gln Gly Arg
        115                 120                 125

Leu Cys Ser Pro Gln Cys Ala Glu Val Arg Gly Phe Ser Asp Lys Asp
    130                 135                 140

Lys Lys Lys Tyr Phe Tyr Lys Xaa Phe Arg Asp Glu Arg Arg Ala Glu
145                 150                 155                 160

Arg Ala Tyr Arg Phe Val Lys Glu Asn Glu Thr Leu Phe Ala Leu Cys
                165                 170                 175

Phe Val Pro Phe Val Cys Trp Ile Val Cys Thr Val Leu Arg Gln Gln
            180                 185                 190

Leu Glu Leu Gly Arg Asp Leu Ser Arg Thr Ser Lys Thr Thr Thr Ser
        195                 200                 205

Val Tyr Leu Leu Phe Ile Thr Ser Val Leu Ser Ser Ala Pro Val Ala
    210                 215                 220

Asp Gly Pro Arg Leu Gln Gly Asp Leu Arg Asn Leu Cys Arg Leu Ala
225                 230                 235                 240

Arg Glu Gly Val Leu Gly Arg Lys Ala Gln Phe Ala Xaa Lys Glu Leu
                245                 250                 255

Glu Gln Leu Glu Leu Arg Gly Ser Lys Ser Ala Asp Ala Cys Phe Ser
            260                 265                 270

Ala Lys Arg Ser Cys Pro Gly Val Leu Xaa Thr Glu Val Thr Tyr Gln
        275                 280                 285

Phe Ile Asp Gln Glu Leu Xaa Arg Ser Ser Ser Arg Ala Leu Val Leu
    290                 295                 300

Pro Cys Trp Lys Asp Gly Arg Gly Gly Pro Arg Asn Arg Arg Xaa Gly
305                 310                 315                 320

Arg 




<210> 2550
<211> 185
<212> PRT
<213> Homo sapiens

<400> 2550
Met Pro Ala Asp Tyr Tyr Cys Asn Thr Leu Thr Ala Ser Gln Val Asp
  1               5                  10                  15

Gln Arg Val Leu Gln Asp Leu Leu Ser Glu Lys Leu Pro Arg Leu Met
             20                  25                  30

Ala His Leu Gly Gln His His Val Asp Leu Ser Leu Val Thr Phe Asn
         35                  40                  45

Trp Phe Leu Val Val Phe Ala Asp Ser Leu Ile Ser Asn Ile Leu Leu
     50                  55                  60

Arg Val Trp Asp Ala Phe Leu Tyr Glu Gly Thr Lys Val Val Phe Arg
 65                  70                  75                  80

Tyr Ala Leu Ala Ile Phe Lys Tyr Asn Glu Lys Glu Ile Leu Arg Leu
                 85                  90                  95

Gln Asn Gly Leu Glu Ile Tyr Gln Tyr Leu Arg Phe Phe Thr Lys Thr
            100                 105                 110

Ile Ser Asn Ser Arg Lys Leu Met Asn Ile Ala Phe Asn Asp Met Asn
        115                 120                 125

Pro Phe Arg Met Lys Gln Leu Arg Gln Leu Arg Met Val His Arg Glu
    130                 135                 140

Arg Leu Glu Ala Glu Leu Arg Glu Leu Glu Gln Leu Lys Ala Glu Tyr
145                 150                 155                 160

Leu Glu Arg Arg Ala Ser Arg Arg Arg Ala Val Ser Glu Gly Cys Ala
                165                 170                 175

Ser Glu Asp Glu Val Glu Gly Glu Ala 
            180                 185



<210> 2551
<211> 218
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (204)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (214)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (217)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2551
Met Asn Gly Gln Pro Leu Thr Cys Val Val Ser His Pro Gly Leu Leu
  1               5                  10                  15

Gln Asp Gln Arg Ile Thr His Ile Leu His Val Ser Phe Leu Ala Glu
             20                  25                  30

Ala Ser Val Arg Gly Leu Glu Asp Gln Asn Leu Trp His Ile Gly Arg
         35                  40                  45

Glu Gly Ala Met Leu Lys Cys Leu Ser Glu Gly Gln Pro Pro Pro Ser
     50                  55                  60

Tyr Asn Trp Thr Arg Leu Asp Gly Pro Leu Pro Ser Gly Val Arg Val
 65                  70                  75                  80

Asp Gly Asp Thr Leu Gly Phe Pro Pro Leu Thr Thr Glu His Ser Gly
                 85                  90                  95

Ile Tyr Val Cys His Val Ser Asn Glu Phe Ser Ser Arg Asp Ser Gln
            100                 105                 110

Val Thr Val Asp Val Leu Asp Pro Gln Glu Asp Ser Gly Lys Gln Val
        115                 120                 125

Asp Leu Val Ser Ala Ser Val Val Val Val Gly Val Ile Ala Ala Leu
    130                 135                 140

Leu Xaa Cys Leu Leu Val Val Val Val Val Leu Met Ser Arg Tyr His
145                 150                 155                 160

Arg Arg Lys Ala Gln Gln Met Thr Gln Lys Tyr Glu Glu Glu Leu Thr
                165                 170                 175

Leu Thr Arg Glu Asn Xaa Ile Arg Arg Leu His Ser His His Thr Asp
            180                 185                 190

Pro Arg Ser Gln Pro Glu Glu Ser Val Gly Leu Xaa Ala Glu Gly His
        195                 200                 205

Pro Asp Ser Leu Lys Xaa Gln Xaa Xaa Leu 
    210                 215



<210> 2552
<211> 108
<212> PRT
<213> Homo sapiens

<400> 2552
Met Phe Arg Pro Leu Met Asn Leu Ser His Ile Tyr Phe Lys Lys Phe
  1               5                  10                  15

Gln Tyr Cys Gly Tyr Ala Pro His Val Arg Ser Cys Lys Pro Asn Thr
             20                  25                  30

Asp Gly Ile Ser Ser Leu Glu Asn Leu Leu Ala Ser Ile Ile Gln Arg
         35                  40                  45

Val Phe Val Trp Val Val Ser Ala Val Thr Cys Phe Gly Asn Ile Phe
     50                  55                  60

Val Ile Cys Met Arg Pro Tyr Ile Arg Ser Glu Asn Lys Leu Tyr Ala
 65                  70                  75                  80

Met Ser Ile Ile Ser Leu Cys Cys Ala Asp Cys Leu Met Gly Ile Tyr
                 85                  90                  95

Leu Phe Val Ile Gly Gly Phe Asp Leu Lys Phe Arg 
            100                 105



<210> 2553
<211> 221
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (215)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2553
Met Thr Leu Thr Cys His Val Glu Gly Gly Thr Arg Leu Ala Tyr Gln
  1               5                  10                  15

Trp Leu Lys Asn Gly Arg Pro Val His Thr Ser Ser Thr Tyr Ser Phe
             20                  25                  30

Ser Pro Gln Asn Asn Thr Leu His Ile Ala Pro Val Thr Lys Glu Asp
         35                  40                  45

Ile Gly Asn Tyr Ser Cys Leu Val Arg Asn Pro Val Ser Glu Met Glu
     50                  55                  60

Ser Asp Ile Ile Met Pro Ile Ile Tyr Tyr Gly Pro Tyr Gly Leu Gln
 65                  70                  75                  80

Val Asn Ser Asp Lys Gly Leu Lys Xaa Gly Glu Val Phe Thr Val Asp
                 85                  90                  95

Leu Gly Glu Ala Ile Leu Phe Asp Cys Ser Ala Asp Ser His Pro Pro
            100                 105                 110

Asn Thr Tyr Ser Trp Ile Arg Arg Thr Asp Asn Thr Thr Tyr Ile Ile
        115                 120                 125

Lys His Gly Pro Arg Leu Glu Val Ala Ser Glu Lys Val Ala Gln Lys
    130                 135                 140

Thr Met Asp Tyr Val Cys Cys Ala Tyr Asn Asn Ile Thr Gly Arg Gln
145                 150                 155                 160

Asp Glu Thr His Phe Thr Val Ile Ile Thr Ser Val Gly Leu Glu Lys
                165                 170                 175

Leu Ala Gln Lys Gly Lys Ser Leu Ser Pro Leu Ala Ser Ile Thr Gly
            180                 185                 190

Ile Ser Leu Phe Leu Ile Ile Ser Met Cys Leu Leu Phe Leu Trp Lys
        195                 200                 205

Lys Tyr Gln Pro Tyr Lys Xaa Ile Lys Lys Lys Lys Lys 
    210                 215                 220



<210> 2554
<211> 121
<212> PRT
<213> Homo sapiens

<400> 2554
Met Arg Ala Asp Pro Pro Lys Phe Asn Arg Ile Trp Pro Asn Ile Ser
  1               5                  10                  15

Ser Leu Glu Val Ser Asn Pro Lys Gln Val Ala Pro Lys Leu Ala Leu
             20                  25                  30

Ser Thr Val Ser Ser Val Gln Val Ala Asn His Lys Arg Ala Asn Val
         35                  40                  45

Cys Asp Asn Glu Leu Leu His Cys Gln Asn Gly Gly Thr Cys His Asn
     50                  55                  60

Asn Val Arg Cys Leu Cys Pro Ala Ala Tyr Thr Gly Ile Leu Cys Glu
 65                  70                  75                  80

Lys Leu Arg Cys Glu Glu Ala Gly Ser Cys Gly Ser Asp Ser Gly Gln
                 85                  90                  95

Gly Ala Pro Pro His Gly Ser Pro Ala Leu Leu Leu Leu Thr Thr Leu
            100                 105                 110

Leu Gly Thr Ala Ser Pro Leu Val Phe 
        115                 120



<210> 2555
<211> 195
<212> PRT
<213> Homo sapiens

<400> 2555
Met Leu Leu Gln Ser Gln Thr Met Gly Val Ser His Ser Phe Thr Pro
  1               5                  10                  15

Lys Gly Ile Thr Ile Pro Gln Arg Glu Lys Pro Gly His Met Tyr Gln
             20                  25                  30

Asn Glu Asp Tyr Leu Gln Asn Gly Leu Pro Thr Glu Thr Thr Val Leu
         35                  40                  45

Gly Phe Gly Ile Thr Gly Ser Leu Ser Ile Ile Ser Gly Lys Gln Ser
     50                  55                  60

Thr Lys Pro Phe Asp Leu Ser Ser Leu Thr Ser Asn Ala Val Ser Ser
 65                  70                  75                  80

Val Thr Ala Gly Ala Gly Leu Phe Leu Leu Ala Asp Ser Met Val Ala
                 85                  90                  95

Leu Arg Thr Ala Ser Gln His Cys Gly Ser Glu Met Asp Tyr Leu Ser
            100                 105                 110

Ser Leu Pro Tyr Ser Glu Tyr Tyr Tyr Pro Ile Tyr Glu Ile Lys Asp
        115                 120                 125

Cys Leu Leu Thr Ser Val Ser Leu Thr Gly Val Leu Val Val Met Leu
    130                 135                 140

Ile Phe Thr Val Leu Glu Leu Leu Leu Ala Ala Tyr Ser Ser Val Phe
145                 150                 155                 160

Trp Trp Lys Gln Leu Tyr Ser Asn Asn Pro Gly Ser Ser Phe Ser Ser
                165                 170                 175

Thr Gln Ser Gln Asp His Ile Gln Gln Val Lys Lys Ser Ser Ser Arg
            180                 185                 190

Ser Trp Ile 
        195



<210> 2556
<211> 106
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2556
Met Thr Met Ile Thr Pro Ser Ser Lys Leu Thr Leu Thr Lys Gly Xaa
  1               5                  10                  15

Lys Ser Trp Ser Ser Thr Ala Val Ala Ala Ala Leu Glu Leu Val Asp
             20                  25                  30

Pro Pro Xaa Cys Arg Asn Ser Ala Arg Glu Asp Ile Thr Glu Ala Ile
         35                  40                  45

Glu Thr Thr Ile Ser Leu Glu Thr Ala Arg Ala Asp His Pro Lys Pro
     50                  55                  60

Val Thr Val Lys Pro Val Thr Thr Glu Pro Gln Ser Pro Asp Leu Asn
 65                  70                  75                  80

Asp Ala Val Ser Ser Leu Arg Ser Pro Ile Pro Leu Leu Leu Ser Cys
                 85                  90                  95

Ala Phe Val Gln Val Gly Met Tyr Phe Met 
            100                 105



<210> 2557
<211> 390
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (217)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (303)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2557
Met Ser Val Arg Val Ala Arg Val Ala Trp Val Arg Gly Leu Gly Ala
  1               5                  10                  15

Ser Tyr Arg Arg Gly Ala Ser Ser Phe Pro Val Pro Pro Pro Gly Ala
             20                  25                  30

Gln Gly Val Ala Glu Leu Leu Arg Asp Ala Thr Gly Ala Glu Glu Glu
         35                  40                  45

Ala Pro Trp Xaa Ala Thr Glu Arg Arg Met Pro Gly Gln Cys Ser Val
     50                  55                  60

Leu Leu Phe Pro Gly Gln Gly Ser Gln Val Val Gly Met Gly Arg Gly
 65                  70                  75                  80

Leu Leu Asn Tyr Pro Arg Val Arg Glu Leu Tyr Ala Ala Ala Arg Arg
                 85                  90                  95

Val Leu Gly Tyr Asp Leu Leu Glu Leu Ser Leu His Gly Pro Gln Glu
            100                 105                 110

Thr Leu Asp Arg Thr Val His Cys Gln Pro Ala Ile Phe Val Ala Ser
        115                 120                 125

Leu Ala Ala Val Glu Lys Leu His His Leu Gln Pro Ser Val Ile Glu
    130                 135                 140

Asn Cys Val Ala Ala Ala Gly Phe Ser Val Gly Glu Phe Ala Ala Leu
145                 150                 155                 160

Val Phe Ala Gly Ala Met Glu Phe Ala Glu Gly Leu Tyr Ala Val Lys
                165                 170                 175

Ile Arg Ala Glu Ala Met Gln Glu Ala Ser Glu Ala Val Pro Ser Gly
            180                 185                 190

Met Leu Ser Val Leu Gly Gln Pro Gln Ser Lys Phe Asn Phe Ala Cys
        195                 200                 205

Leu Glu Ala Arg Glu His Cys Lys Xaa Leu Gly Ile Glu Asn Pro Val
    210                 215                 220

Cys Glu Val Ser Asn Tyr Leu Phe Pro Asp Cys Arg Val Ile Ser Gly
225                 230                 235                 240

His Gln Glu Ala Leu Arg Phe Leu Gln Lys Asn Ser Ser Lys Phe His
                245                 250                 255

Phe Arg Arg Thr Arg Met Leu Pro Val Ser Gly Ala Phe His Thr Arg
            260                 265                 270

Leu Met Glu Pro Ala Val Glu Pro Leu Thr Gln Ala Leu Lys Ala Val
        275                 280                 285

Asp Ile Lys Lys Pro Leu Val Ser Val Tyr Ser Asn Val His Xaa His
    290                 295                 300

Arg Tyr Arg His Pro Gly His Ile His Lys Leu Leu Ala Gln Gln Leu
305                 310                 315                 320

Val Ser Pro Val Lys Trp Glu Gln Thr Met His Ala Ile Tyr Glu Arg
                325                 330                 335

Lys Lys Gly Arg Gly Phe Pro Gln Thr Phe Glu Val Gly Pro Gly Arg
            340                 345                 350

Gln Leu Gly Ala Ile Leu Lys Ser Cys Asn Met Gln Ala Trp Lys Ser
        355                 360                 365

Tyr Ser Ala Val Asp Val Leu Gln Thr Leu Glu His Val Asp Leu Asp
    370                 375                 380

Pro Gln Glu Pro Pro Arg 
385                 390



<210> 2558
<211> 311
<212> PRT
<213> Homo sapiens

<400> 2558
Met Gln Thr Phe Thr Met Val Leu Glu Glu Ile Trp Thr Ser Leu Phe
  1               5                  10                  15

Met Trp Phe Phe Tyr Ala Leu Ile Pro Cys Leu Leu Thr Asp Glu Val
             20                  25                  30

Ala Ile Leu Pro Ala Pro Gln Asn Leu Ser Val Leu Ser Thr Asn Met
         35                  40                  45

Lys His Leu Leu Met Trp Ser Pro Val Ile Ala Pro Gly Glu Thr Val
     50                  55                  60

Tyr Tyr Ser Val Glu Tyr Gln Gly Glu Tyr Glu Ser Leu Tyr Thr Ser
 65                  70                  75                  80

His Ile Trp Ile Pro Ser Ser Trp Cys Ser Leu Thr Glu Gly Pro Glu
                 85                  90                  95

Cys Asp Val Thr Asp Asp Ile Thr Ala Thr Val Pro Tyr Asn Leu Arg
            100                 105                 110

Val Arg Ala Thr Leu Gly Ser Gln Thr Ser Ala Trp Ser Ile Leu Lys
        115                 120                 125

His Pro Phe Asn Arg Asn Ser Thr Ile Leu Thr Arg Pro Gly Met Glu
    130                 135                 140

Ile Thr Lys Asp Gly Phe His Leu Val Ile Glu Leu Glu Asp Leu Gly
145                 150                 155                 160

Pro Gln Phe Glu Phe Leu Val Ala Tyr Trp Arg Arg Glu Pro Gly Ala
                165                 170                 175

Glu Glu His Val Lys Met Val Arg Ser Gly Gly Ile Pro Val His Leu
            180                 185                 190

Glu Thr Met Glu Pro Gly Ala Ala Tyr Cys Val Lys Ala Gln Thr Phe
        195                 200                 205

Val Lys Ala Ile Gly Arg Tyr Ser Ala Phe Ser Gln Thr Glu Cys Val
    210                 215                 220

Glu Val Gln Gly Glu Ala Ile Pro Leu Val Leu Ala Leu Phe Ala Phe
225                 230                 235                 240

Val Gly Phe Met Leu Ile Leu Val Val Val Pro Leu Phe Val Trp Lys
                245                 250                 255

Met Gly Arg Leu Leu Gln Tyr Ser Cys Cys Pro Val Val Val Leu Pro
            260                 265                 270

Asp Thr Leu Lys Ile Thr Asn Ser Pro Gln Lys Leu Ile Ser Cys Arg
        275                 280                 285

Arg Glu Glu Val Asp Ala Cys Ala Thr Ala Val Met Ser Pro Glu Glu
    290                 295                 300

Leu Leu Arg Ala Trp Ile Ser 
305                 310



<210> 2559
<211> 331
<212> PRT
<213> Homo sapiens

<400> 2559
Met Leu Trp Leu Phe Gln Ser Leu Leu Phe Val Phe Cys Phe Gly Pro
  1               5                  10                  15

Gly Asn Val Val Ser Gln Ser Ser Leu Thr Pro Leu Met Val Asn Gly
             20                  25                  30

Ile Leu Gly Glu Ser Val Thr Leu Pro Leu Glu Phe Pro Ala Gly Glu
         35                  40                  45

Lys Val Asn Phe Ile Thr Trp Leu Phe Asn Glu Thr Ser Leu Ala Phe
     50                  55                  60

Ile Val Pro His Glu Thr Lys Ser Pro Glu Ile His Val Thr Asn Pro
 65                  70                  75                  80

Lys Gln Gly Lys Arg Leu Asn Phe Thr Gln Ser Tyr Ser Leu Gln Leu
                 85                  90                  95

Ser Asn Leu Lys Met Glu Asp Thr Gly Ser Tyr Arg Ala Gln Ile Ser
            100                 105                 110

Thr Lys Thr Ser Ala Lys Leu Ser Ser Tyr Thr Leu Arg Ile Leu Arg
        115                 120                 125

Gln Leu Arg Asn Ile Gln Val Thr Asn His Ser Gln Leu Phe Gln Asn
    130                 135                 140

Met Thr Cys Glu Leu His Leu Thr Cys Ser Val Glu Asp Ala Asp Asp
145                 150                 155                 160

Asn Val Ser Phe Arg Trp Glu Ala Leu Gly Asn Thr Leu Ser Ser Gln
                165                 170                 175

Pro Asn Leu Thr Val Ser Trp Asp Pro Arg Ile Ser Ser Glu Gln Asp
            180                 185                 190

Tyr Thr Cys Ile Ala Glu Asn Ala Val Ser Asn Leu Ser Phe Ser Val
        195                 200                 205

Ser Ala Gln Lys Leu Cys Glu Asp Val Lys Ile Gln Tyr Thr Asp Thr
    210                 215                 220

Lys Met Ile Leu Phe Met Val Ser Gly Ile Cys Ile Val Phe Gly Phe
225                 230                 235                 240

Ile Ile Leu Leu Leu Leu Val Leu Arg Lys Arg Arg Asp Ser Leu Ser
                245                 250                 255

Leu Ser Thr Gln Arg Thr Gln Gly Pro Glu Ser Ala Arg Asn Leu Glu
            260                 265                 270

Tyr Val Ser Val Ser Pro Thr Asn Asn Thr Val Tyr Ala Ser Val Thr
        275                 280                 285

His Ser Asn Arg Glu Thr Glu Ile Trp Thr Pro Arg Glu Asn Asp Thr
    290                 295                 300

Ile Thr Ile Tyr Ser Thr Ile Asn His Ser Lys Glu Ser Lys Pro Thr
305                 310                 315                 320

Phe Ser Arg Ala Thr Ala Leu Asp Asn Val Val 
                325                 330



<210> 2560
<211> 117
<212> PRT
<213> Homo sapiens

<400> 2560
Met Thr Met Ile Thr Pro Ser Ser Lys Leu Thr Leu Thr Lys Gly Asn
  1               5                  10                  15

Lys Ser Trp Ser Ser Thr Ala Val Ala Ala Ala Leu Glu Leu Val Asp
             20                  25                  30

Pro Pro Gly Cys Arg Asn Ser Ala Arg Ala Trp Leu Leu Gln Asn Phe
         35                  40                  45

Leu Leu Phe Leu Leu Leu Leu Val Phe Ser Leu Leu Cys Phe Thr Leu
     50                  55                  60

Cys Ser Cys Pro Thr Val Leu Asp Ile Ile Phe Cys Ser Phe Gln Cys
 65                  70                  75                  80

Phe Phe Ser Leu Val Phe Glu Val Ser Asp Asp Lys Ser Ser Ser Ser
                 85                  90                  95

Glu Ile Leu Tyr Ser Ala Glu Ser Ser Leu Leu Ile Ser His Gln Arg
            100                 105                 110

Tyr Ser Ser Val Ile 
        115



<210> 2561
<211> 187
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (179)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2561
Met Ser Glu Glu Val Thr Tyr Ala Asp Leu Gln Phe Gln Asn Ser Ser
  1               5                  10                  15

Glu Met Glu Lys Ile Pro Glu Ile Gly Lys Phe Gly Glu Lys Ala Pro
             20                  25                  30

Pro Ala Pro Ser His Val Trp Arg Pro Ala Ala Leu Phe Leu Thr Leu
         35                  40                  45

Leu Cys Leu Leu Leu Leu Ile Gly Leu Gly Val Leu Ala Ser Met Phe
     50                  55                  60

His Val Thr Leu Lys Ile Glu Met Lys Lys Met Asn Lys Leu Gln Asn
 65                  70                  75                  80

Ile Ser Glu Glu Leu Gln Arg Asn Ile Ser Leu Gln Leu Met Ser Asn
                 85                  90                  95

Met Asn Ile Ser Asn Lys Ile Arg Asn Leu Ser Thr Thr Leu Gln Thr
            100                 105                 110

Ile Ala Thr Lys Leu Xaa Arg Glu Leu Tyr Xaa Lys Glu Xaa Glu His
        115                 120                 125

Lys Cys Lys Pro Cys Pro Arg Arg Trp Ile Trp His Lys Asp Ser Cys
    130                 135                 140

Tyr Phe Leu Ser Asp Asp Val Gln Thr Trp Gln Glu Ser Lys Met Ala
145                 150                 155                 160

Cys Ala Ala Gln Asn Ala Ser Leu Leu Lys Ile Asn Asn Lys Asn Ala
                165                 170                 175

Leu Glu Xaa Val Lys Ser Gln Ser Gly Asn Arg 
            180                 185



<210> 2562
<211> 307
<212> PRT
<213> Homo sapiens

<400> 2562
Met Gly Gly Phe Gln Arg Gly Lys Tyr Gly Thr Met Ala Glu Gly Arg
  1               5                  10                  15

Ser Glu Asp Asn Leu Ser Ala Thr Pro Pro Ala Leu Arg Ile Ile Leu
             20                  25                  30

Val Gly Lys Thr Gly Cys Gly Lys Ser Ala Thr Gly Asn Ser Ile Leu
         35                  40                  45

Gly Gln Pro Val Phe Glu Ser Lys Leu Arg Ala Gln Ser Val Thr Arg
     50                  55                  60

Thr Cys Gln Val Lys Thr Gly Thr Trp Asn Gly Arg Lys Val Leu Val
 65                  70                  75                  80

Val Asp Thr Pro Ser Ile Phe Glu Ser Gln Ala Asp Thr Gln Glu Leu
                 85                  90                  95

Tyr Lys Asn Ile Gly Asp Cys Tyr Leu Leu Ser Ala Pro Gly Pro His
            100                 105                 110

Val Leu Leu Leu Val Ile Gln Leu Gly Arg Phe Thr Ala Gln Asp Thr
        115                 120                 125

Val Ala Ile Arg Lys Val Lys Glu Val Phe Gly Thr Gly Ala Met Arg
    130                 135                 140

His Val Val Ile Leu Phe Thr His Lys Glu Asp Leu Gly Gly Gln Ala
145                 150                 155                 160

Leu Asp Asp Tyr Val Ala Asn Thr Asp Asn Cys Ser Leu Lys Asp Leu
                165                 170                 175

Val Arg Glu Cys Glu Arg Arg Tyr Cys Ala Phe Asn Asn Trp Gly Ser
            180                 185                 190

Val Glu Glu Gln Arg Gln Gln Gln Ala Glu Leu Leu Ala Val Ile Glu
        195                 200                 205

Arg Leu Gly Arg Glu Arg Glu Gly Ser Phe His Ser Asn Asp Leu Phe
    210                 215                 220

Leu Asp Ala Gln Leu Leu Gln Arg Thr Gly Ala Gly Ala Cys Gln Glu
225                 230                 235                 240

Asp Tyr Arg Gln Tyr Gln Ala Lys Val Glu Trp Gln Val Glu Lys His
                245                 250                 255

Lys Gln Glu Leu Arg Glu Asn Glu Ser Asn Trp Ala Tyr Lys Ala Leu
            260                 265                 270

Leu Arg Val Lys His Leu Met Leu Leu His Tyr Glu Ile Phe Val Phe
        275                 280                 285

Leu Leu Leu Cys Ser Ile Leu Phe Phe Ile Ile Phe Leu Phe Ile Phe
    290                 295                 300

His Tyr Ile 
305



<210> 2563
<211> 121
<212> PRT
<213> Homo sapiens

<400> 2563
Met Val Pro Ala Leu Arg Tyr Leu Val Gly Ala Cys Gly Arg Ala Arg
  1               5                  10                  15

Gly Leu Phe Ala Gly Gly Ser Pro Gly Ala Cys Gly Phe Ala Ser Gly
             20                  25                  30

Arg Pro Arg Pro Leu Cys Gly Gly Ser Arg Ser Ala Ser Thr Ser Ser
         35                  40                  45

Phe Asp Ile Val Ile Val Gly Gly Gly Ile Val Gly Leu Ala Ser Ala
     50                  55                  60

Arg Ala Leu Ile Leu Arg His Pro Ser Leu Ser Ile Gly Val Leu Glu
 65                  70                  75                  80

Lys Glu Lys Asp Leu Ala Val His Gln Thr Gly His Asn Ser Gly Val
                 85                  90                  95

Ile His Ser Gly Ile Tyr Tyr Lys Pro Glu Ser Leu Lys Ser Gln Ile
            100                 105                 110

Met Cys Thr Arg Cys Ser Pro Pro Leu 
        115                 120



<210> 2564
<211> 256
<212> PRT
<213> Homo sapiens

<400> 2564
Met Ala Leu Leu His Tyr Leu Met Tyr Leu Val Met Val Ala Ala Ile
  1               5                  10                  15

Ala Trp Glu Glu Thr Tyr Arg Thr Ile Gly Leu Tyr Trp Val Gly Ser
             20                  25                  30

Ile Ile Met Ser Val Val Val Phe Val Pro Gly Asn Ile Val Gly Lys
         35                  40                  45

Tyr Gly Thr Arg Ile Cys Pro Ala Phe Phe Leu Ser Ile Pro Tyr Thr
     50                  55                  60

Cys Leu Pro Val Trp Ala Gly Phe Arg Ile Tyr Asn Gln Pro Ser Glu
 65                  70                  75                  80

Asn Tyr Asn Tyr Pro Ser Lys Val Ile Gln Glu Ala Gln Ala Lys Asp
                 85                  90                  95

Leu Leu Arg Arg Pro Phe Asp Leu Met Leu Val Val Cys Leu Leu Leu
            100                 105                 110

Ala Thr Gly Phe Cys Leu Phe Arg Gly Leu Ile Ala Leu Asp Cys Pro
        115                 120                 125

Ser Glu Leu Cys Arg Leu Tyr Thr Gln Phe Gln Glu Pro Tyr Leu Lys
    130                 135                 140

Asp Pro Ala Ala Tyr Pro Lys Ile Gln Met Leu Ala Tyr Met Phe Tyr
145                 150                 155                 160

Ser Val Pro Tyr Phe Val Thr Ala Leu Tyr Gly Leu Val Val Pro Gly
                165                 170                 175

Cys Ser Trp Met Pro Asp Ile Thr Leu Ile His Ala Gly Gly Leu Ala
            180                 185                 190

Gln Ala Gln Phe Ser His Ile Gly Ala Ser Leu His Ala Arg Thr Ala
        195                 200                 205

Tyr Val Tyr Arg Val Pro Glu Glu Ala Lys Ile Leu Phe Leu Ala Leu
    210                 215                 220

Asn Ile Ala Tyr Gly Val Leu Pro Gln Leu Leu Ala Tyr Arg Cys Ile
225                 230                 235                 240

Tyr Lys Pro Glu Phe Phe Ile Lys Thr Lys Ala Glu Glu Lys Val Glu
                245                 250                 255






<210> 2565
<211> 232
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2565
Met Thr Val Glu Lys Glu Ala Pro Asp Ala His Phe Thr Val Asp Lys
  1               5                  10                  15

Gln Asn Ile Ser Leu Trp Pro Arg Glu Pro Pro Pro Lys Ser Gly Pro
             20                  25                  30

Ser Leu Val Pro Gly Lys Thr Pro Thr Val Arg Ala Ala Leu Ile Cys
         35                  40                  45

Leu Thr Leu Val Leu Val Ala Ser Val Leu Leu Gln Ala Val Leu Tyr
     50                  55                  60

Pro Arg Phe Met Gly Thr Ile Ser Asp Val Lys Thr Asn Val Gln Leu
 65                  70                  75                  80

Leu Lys Gly Arg Val Asp Asn Ile Ser Thr Leu Asp Ser Glu Ile Lys
                 85                  90                  95

Lys Asn Ser Asp Gly Met Glu Ala Ala Gly Val Gln Ile Gln Met Val
            100                 105                 110

Asn Xaa Ser Leu Gly Tyr Val Arg Ser Gln Phe Leu Lys Leu Lys Thr
        115                 120                 125

Ser Val Glu Lys Ala Asn Ala Xaa Ile Gln Ile Leu Thr Arg Ser Trp
    130                 135                 140

Glu Glu Val Ser Thr Leu Asn Ala Gln Ile Pro Glu Leu Lys Ser Asp
145                 150                 155                 160

Leu Glu Lys Ala Ser Ala Leu Asn Thr Lys Ile Arg Ala Leu Gln Gly
                165                 170                 175

Ser Leu Glu Asn Met Ser Lys Leu Leu Lys Arg Gln Asn Asp Ile Leu
            180                 185                 190

Gln Val Val Ser Gln Gly Trp Lys Tyr Phe Lys Gly Asn Phe Tyr Tyr
        195                 200                 205

Phe Ser Leu Ile Pro Lys Thr Trp Tyr Ser Ala Glu Gln Phe Cys Val
    210                 215                 220

Ser Arg Asn Ser His Leu Thr Ser 
225                 230



<210> 2566
<211> 250
<212> PRT
<213> Homo sapiens

<400> 2566
Met Asn Ser Met Thr Ser Ala Val Pro Val Ala Asn Ser Val Leu Val
  1               5                  10                  15

Val Ala Pro His Asn Gly Tyr Pro Val Thr Pro Gly Ile Met Ser His
             20                  25                  30

Val Pro Leu Tyr Pro Asn Ser Gln Pro Gln Val His Leu Val Pro Gly
         35                  40                  45

Asn Pro Pro Ser Leu Val Ser Asn Val Asn Gly Gln Pro Val Gln Lys
     50                  55                  60

Ala Leu Lys Glu Gly Lys Thr Leu Gly Ala Ile Gln Ile Ile Ile Gly
 65                  70                  75                  80

Leu Ala His Ile Gly Leu Gly Ser Ile Met Ala Thr Val Leu Val Gly
                 85                  90                  95

Glu Tyr Leu Ser Ile Ser Phe Tyr Gly Gly Phe Pro Phe Trp Gly Gly
            100                 105                 110

Leu Trp Phe Ile Ile Ser Gly Ser Leu Ser Val Ala Ala Glu Asn Gln
        115                 120                 125

Pro Tyr Ser Tyr Cys Leu Leu Ser Gly Ser Leu Gly Leu Asn Ile Val
    130                 135                 140

Ser Ala Ile Cys Ser Ala Val Gly Val Ile Leu Phe Ile Thr Asp Leu
145                 150                 155                 160

Ser Ile Pro His Pro Tyr Ala Tyr Pro Asp Tyr Tyr Pro Tyr Ala Trp
                165                 170                 175

Gly Val Asn Pro Gly Met Ala Ile Ser Gly Val Leu Leu Val Phe Cys
            180                 185                 190

Leu Leu Glu Phe Gly Ile Ala Cys Ala Ser Ser His Phe Gly Cys Gln
        195                 200                 205

Leu Val Cys Cys Gln Ser Ser Asn Val Ser Val Ile Tyr Pro Asn Ile
    210                 215                 220

Tyr Ala Ala Asn Pro Val Ile Thr Pro Glu Pro Val Thr Ser Pro Pro
225                 230                 235                 240

Ser Tyr Ser Ser Glu Ile Gln Ala Asn Lys 
                245                 250



<210> 2567
<211> 286
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (7)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (20)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2567
Met Thr Met Ile Thr Pro Xaa Ser Lys Leu Thr Leu Xaa Lys Gly Asn
  1               5                  10                  15

Lys Ser Trp Xaa Ser Thr Ala Val Ala Ala Ala Leu Glu Leu Val Asp
             20                  25                  30

Pro Pro Gly Cys Arg Asn Ser Ala Arg Val Gly Cys Ser Arg Ser Arg
         35                  40                  45

Gln Pro Gln Ala Arg Gly Gly Arg Trp Ala Arg Asp Pro Thr Leu Val
     50                  55                  60

Val Met Glu Ala Gly Gly Phe Leu Asp Ser Leu Ile Tyr Gly Ala Cys
 65                  70                  75                  80

Val Val Phe Thr Leu Gly Met Phe Ser Ala Gly Leu Ser Asp Leu Arg
                 85                  90                  95

His Met Arg Met Thr Arg Ser Val Asp Asn Val Gln Phe Leu Pro Phe
            100                 105                 110

Leu Thr Thr Glu Val Asn Asn Leu Gly Trp Leu Ser Tyr Gly Ala Leu
        115                 120                 125

Lys Gly Asp Gly Ile Leu Ile Val Val Asn Thr Val Gly Ala Ala Leu
    130                 135                 140

Gln Thr Leu Tyr Ile Leu Ala Tyr Leu His Tyr Cys Pro Arg Lys Arg
145                 150                 155                 160

Val Val Leu Leu Gln Thr Ala Thr Leu Leu Gly Val Leu Leu Leu Gly
                165                 170                 175

Tyr Gly Tyr Phe Trp Leu Leu Val Pro Asn Pro Glu Ala Arg Leu Gln
            180                 185                 190

Gln Leu Gly Leu Phe Cys Ser Val Phe Thr Ile Ser Met Tyr Leu Ser
        195                 200                 205

Pro Leu Ala Asp Leu Ala Lys Val Ile Gln Thr Lys Ser Thr Gln Cys
    210                 215                 220

Leu Ser Tyr Pro Leu Thr Ile Ala Thr Leu Leu Thr Ser Ala Ser Trp
225                 230                 235                 240

Cys Leu Tyr Gly Phe Arg Leu Arg Asp Pro Tyr Ile Met Val Ser Asn
                245                 250                 255

Phe Pro Gly Ile Val Thr Ser Phe Ile Arg Phe Trp Leu Phe Trp Lys
            260                 265                 270

Tyr Pro Gln Glu Gln Asp Arg Asn Tyr Trp Leu Leu Gln Thr 
        275                 280                 285



<210> 2568
<211> 270
<212> PRT
<213> Homo sapiens

<400> 2568
Met Thr Ser Ala Leu Arg Gly Val Ala Asp Asp Gln Gly Gln His Pro
  1               5                  10                  15

Leu Leu Lys Met Leu Leu His Leu Leu Ala Phe Ser Ser Ala Ala Thr
             20                  25                  30

Gly His Leu Gln Ala Ser Val Leu Thr Gln Cys Leu Lys Val Leu Val
         35                  40                  45

Lys Leu Ala Glu Asn Thr Ser Cys Asp Phe Leu Pro Arg Phe Gln Cys
     50                  55                  60

Val Phe Gln Val Leu Pro Lys Cys Leu Ser Pro Glu Thr Pro Leu Pro
 65                  70                  75                  80

Ser Val Leu Leu Ala Val Glu Leu Leu Ser Leu Leu Ala Asp His Asp
                 85                  90                  95

Gln Leu Ala Pro Gln Leu Cys Ser His Ser Glu Gly Cys Leu Leu Leu
            100                 105                 110

Leu Leu Tyr Met Tyr Ile Thr Ser Arg Pro Asp Arg Val Ala Leu Glu
        115                 120                 125

Thr Gln Trp Leu Gln Leu Glu Gln Glu Val Val Trp Leu Leu Ala Lys
    130                 135                 140

Leu Gly Val Gln Ser Pro Leu Pro Pro Val Thr Gly Ser Asn Cys Gln
145                 150                 155                 160

Cys Asn Val Glu Val Val Arg Ala Leu Thr Val Met Leu His Arg Gln
                165                 170                 175

Trp Leu Thr Val Arg Arg Ala Gly Gly Pro Pro Arg Thr Asp Gln Gln
            180                 185                 190

Arg Arg Thr Val Arg Cys Leu Arg Asp Thr Val Leu Leu Leu His Gly
        195                 200                 205

Leu Ser Gln Lys Asp Lys Leu Phe Met Met His Cys Val Glu Val Leu
    210                 215                 220

His Gln Phe Asp Gln Val Met Pro Gly Val Ser Met Leu Ile Arg Gly
225                 230                 235                 240

Leu Pro Asp Val Thr Asp Cys Glu Glu Ala Ala Leu Asp Asp Leu Cys
                245                 250                 255

Ala Ala Glu Thr Asp Val Glu Asp Pro Glu Val Glu Cys Gly 
            260                 265                 270



<210> 2569
<211> 341
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (276)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (279)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (322)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (323)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (326)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2569
Met Arg Lys Val Val Leu Ile Thr Gly Ala Ser Ser Gly Ile Gly Leu
  1               5                  10                  15

Ala Leu Cys Lys Arg Leu Leu Ala Glu Asp Asp Glu Leu His Leu Cys
             20                  25                  30

Leu Ala Cys Arg Asn Met Ser Lys Ala Glu Ala Val Cys Ala Ala Leu
         35                  40                  45

Leu Ala Ser His Pro Thr Ala Glu Val Thr Ile Val Gln Val Asp Val
     50                  55                  60

Ser Asn Leu Gln Ser Val Phe Arg Ala Ser Lys Glu Leu Lys Gln Arg
 65                  70                  75                  80

Phe Gln Arg Leu Asp Cys Ile Tyr Leu Asn Ala Gly Ile Met Pro Asn
                 85                  90                  95

Pro Gln Leu Asn Ile Lys Ala Leu Phe Phe Gly Leu Phe Ser Arg Lys
            100                 105                 110

Val Ile His Met Phe Ser Thr Ala Glu Gly Leu Leu Thr Gln Gly Asp
        115                 120                 125

Lys Ile Thr Ala Asp Gly Leu Gln Glu Val Phe Glu Thr Asn Val Phe
    130                 135                 140

Gly His Phe Ile Leu Ile Arg Glu Leu Glu Pro Leu Leu Cys His Ser
145                 150                 155                 160

Asp Asn Pro Ser Gln Leu Ile Trp Thr Ser Ser Arg Ser Ala Arg Lys
                165                 170                 175

Ser Asn Phe Ser Leu Glu Asp Phe Gln His Ser Lys Gly Lys Glu Pro
            180                 185                 190

Tyr Ser Ser Ser Lys Tyr Ala Thr Asp Leu Leu Ser Val Ala Leu Asn
        195                 200                 205

Arg Asn Phe Asn Gln Gln Gly Leu Tyr Ser Asn Val Ala Cys Pro Gly
    210                 215                 220

Thr Ala Leu Thr Asn Leu Thr Tyr Gly Ile Leu Pro Pro Phe Ile Trp
225                 230                 235                 240

Thr Leu Leu Met Pro Ala Ile Leu Leu Leu Arg Phe Phe Ala Asn Ala
                245                 250                 255

Phe Thr Leu Thr Pro Tyr Asn Gly Thr Glu Ala Leu Val Trp Leu Phe
            260                 265                 270

His Gln Lys Xaa Glu Ser Xaa Asn Pro Leu Ile Lys Tyr Leu Ser Ala
        275                 280                 285

Thr Thr Gly Phe Gly Arg Asn Tyr Ile Met Thr Gln Lys Met Asp Leu
    290                 295                 300

Asp Glu Asp Thr Ala Glu Lys Phe Tyr Gln Lys Leu Leu Glu Leu Glu
305                 310                 315                 320

Lys Xaa Xaa Arg Val Xaa Ile Gln Lys Thr Asp Asn Gln Ala Arg Leu
                325                 330                 335

Ser Gly Ser Cys Leu 
            340



<210> 2570
<211> 241
<212> PRT
<213> Homo sapiens

<400> 2570
Met Thr Leu Gln Trp Ala Ala Val Ala Thr Phe Leu Tyr Ala Glu Ile
  1               5                  10                  15

Gly Leu Ile Leu Ile Phe Cys Leu Pro Phe Ile Pro Pro Gln Arg Trp
             20                  25                  30

Gln Lys Ile Phe Ser Phe Asn Val Trp Gly Lys Ile Ala Thr Phe Trp
         35                  40                  45

Asn Lys Ala Phe Leu Thr Ile Ile Ile Leu Leu Ile Val Leu Phe Leu
     50                  55                  60

Asp Ala Val Arg Glu Val Arg Lys Tyr Ser Ser Val His Thr Ile Glu
 65                  70                  75                  80

Lys Ser Ser Thr Ser Arg Pro Asp Ala Tyr Glu His Thr Gln Met Lys
                 85                  90                  95

Leu Phe Arg Ser Gln Arg Asn Leu Tyr Ile Ser Gly Phe Ser Leu Phe
            100                 105                 110

Phe Trp Leu Val Leu Arg Arg Leu Val Thr Leu Ile Thr Gln Leu Ala
        115                 120                 125

Lys Glu Leu Ser Asn Lys Gly Val Leu Lys Thr Gln Ala Glu Asn Thr
    130                 135                 140

Asn Lys Ala Ala Lys Lys Phe Met Glu Glu Asn Glu Lys Leu Lys Arg
145                 150                 155                 160

Ile Leu Lys Ser His Gly Lys Asp Glu Glu Cys Val Leu Glu Ala Glu
                165                 170                 175

Asn Lys Lys Leu Val Glu Asp Gln Glu Lys Leu Lys Thr Glu Leu Arg
            180                 185                 190

Lys Thr Ser Asp Ala Leu Ser Lys Ala Gln Asn Asp Val Met Glu Met
        195                 200                 205

Lys Met Gln Ser Glu Arg Leu Ser Lys Glu Tyr Asp Gln Leu Leu Lys
    210                 215                 220

Glu His Ser Glu Leu Gln Asp Arg Leu Glu Arg Gly Asn Lys Lys Arg
225                 230                 235                 240

Leu 




<210> 2571
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2571
Met Ala Xaa Ile His Thr Pro Tyr Ser Ser Leu Lys Lys Leu Leu Ser
  1               5                  10                  15

Leu Leu Asn Gly Phe Val Ala Val Ser Gly Ile Ile Leu Val Gly Leu
             20                  25                  30

Gly Ile Gly Gly Lys Cys Gly Gly Ala Ser Leu Thr Asn Val Leu Gly
         35                  40                  45

Leu Ser Ser Ala Tyr Leu Leu His Val Gly Asn Leu Cys Leu Val Met
     50                  55                  60

Gly Cys Ile Thr Val Leu Leu Gly Cys Ala Gly Trp Tyr Gly Ala Thr
 65                  70                  75                  80

Lys Glu Ser Arg Gly Thr Leu Leu Phe Val Gly Asp Val Ala Leu Glu
                 85                  90                  95

His Thr Phe Val Thr Leu Arg Lys Asn Tyr Arg Gly Tyr Asn Glu Pro
            100                 105                 110

Asp Asp Tyr Ser Thr Gln Trp Asn Leu Val 
        115                 120



<210> 2572
<211> 778
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2572
Met Ala Gln Lys Met Asp Cys Gly Ala Gly Leu Leu Gly Phe Gln Ala
  1               5                  10                  15

Glu Ala Ser Val Glu Asp Ser Ala Leu Leu Met Gln Thr Leu Met Glu
             20                  25                  30

Ala Ile Gln Ile Ser Glu Ala Pro Pro Thr Asn Gln Ala Thr Ala Ala
         35                  40                  45

Ala Ser Pro Gln Ser Ser Gln Pro Pro Thr Ala Asn Glu Met Ala Asp
     50                  55                  60

Ile Gln Val Ser Ala Ala Ala Ala Arg Xaa Lys Ser Ala Phe Lys Val
 65                  70                  75                  80

Gln Asn Ala Thr Thr Lys Gly Pro Asn Gly Val Tyr Asp Phe Ser Gln
                 85                  90                  95

Ala His Asn Ala Lys Asp Val Pro Asn Thr Gln Pro Lys Ala Ala Phe
            100                 105                 110

Lys Ser Gln Asn Ala Thr Pro Lys Gly Pro Asn Ala Ala Tyr Asp Phe
        115                 120                 125

Ser Gln Ala Ala Thr Thr Gly Glu Leu Ala Ala Asn Lys Ser Glu Met
    130                 135                 140

Ala Phe Lys Ala Gln Asn Ala Thr Thr Lys Val Gly Pro Asn Ala Thr
145                 150                 155                 160

Tyr Asn Phe Ser Gln Ser Leu Asn Ala Asn Asp Leu Ala Asn Ser Arg
                165                 170                 175

Pro Lys Thr Pro Phe Lys Ala Trp Asn Asp Thr Thr Lys Ala Pro Thr
            180                 185                 190

Ala Asp Thr Gln Thr Gln Asn Val Asn Gln Ala Lys Met Ala Thr Ser
        195                 200                 205

Gln Ala Asp Ile Glu Thr Asp Pro Gly Ile Ser Glu Pro Asp Gly Ala
    210                 215                 220

Thr Ala Gln Thr Ser Ala Asp Gly Ser Gln Ala Gln Asn Leu Glu Ser
225                 230                 235                 240

Arg Thr Ile Ile Arg Gly Lys Arg Thr Arg Lys Ile Asn Asn Leu Asn
                245                 250                 255

Val Glu Glu Asn Ser Ser Gly Asp Gln Arg Arg Ala Pro Leu Ala Ala
            260                 265                 270

Gly Thr Trp Arg Ser Ala Pro Val Pro Val Thr Thr Gln Asn Pro Pro
        275                 280                 285

Gly Ala Pro Pro Asn Val Leu Trp Gln Thr Pro Leu Ala Trp Gln Asn
    290                 295                 300

Pro Ser Gly Trp Gln Asn Gln Thr Ala Arg Gln Thr Pro Pro Ala Arg
305                 310                 315                 320

Gln Ser Pro Pro Ala Arg Gln Thr Pro Pro Ala Trp Gln Asn Pro Val
                325                 330                 335

Ala Trp Gln Asn Pro Val Ile Trp Pro Asn Pro Val Ile Trp Gln Asn
            340                 345                 350

Pro Val Ile Trp Pro Asn Pro Ile Val Trp Pro Gly Pro Val Val Trp
        355                 360                 365

Pro Asn Pro Leu Ala Trp Gln Asn Pro Pro Gly Trp Gln Thr Pro Pro
    370                 375                 380

Gly Trp Gln Thr Pro Pro Gly Trp Gln Gly Pro Pro Asp Trp Gln Gly
385                 390                 395                 400

Pro Pro Asp Trp Pro Leu Pro Pro Asp Trp Pro Leu Pro Pro Asp Trp
                405                 410                 415

Pro Leu Pro Thr Asp Trp Pro Leu Pro Pro Asp Trp Ile Pro Ala Asp
            420                 425                 430

Trp Pro Ile Pro Pro Asp Trp Gln Asn Leu Arg Pro Ser Pro Asn Leu
        435                 440                 445

Arg Pro Ser Pro Asn Ser Arg Ala Ser Gln Asn Pro Gly Ala Ala Gln
    450                 455                 460

Pro Arg Asp Val Ala Leu Leu Gln Glu Arg Ala Asn Lys Leu Val Lys
465                 470                 475                 480

Tyr Leu Met Leu Lys Asp Tyr Thr Lys Val Pro Ile Lys Arg Ser Glu
                485                 490                 495

Met Leu Arg Asp Ile Ile Arg Glu Tyr Thr Asp Val Tyr Pro Glu Ile
            500                 505                 510

Ile Glu Arg Ala Cys Phe Val Leu Glu Lys Lys Phe Gly Ile Gln Leu
        515                 520                 525

Lys Glu Ile Asp Lys Glu Glu His Leu Tyr Ile Leu Ile Ser Thr Pro
    530                 535                 540

Glu Ser Leu Ala Gly Ile Leu Gly Thr Thr Lys Asp Thr Pro Lys Leu
545                 550                 555                 560

Gly Leu Leu Leu Val Ile Leu Gly Val Ile Phe Met Asn Gly Asn Arg
                565                 570                 575

Ala Ser Glu Ala Val Leu Trp Glu Ala Leu Arg Lys Met Gly Leu Arg
            580                 585                 590

Pro Gly Val Arg His Pro Leu Leu Gly Asp Leu Arg Lys Leu Leu Thr
        595                 600                 605

Tyr Glu Phe Val Lys Gln Lys Tyr Leu Asp Tyr Arg Arg Val Pro Asn
    610                 615                 620

Ser Asn Pro Pro Glu Tyr Glu Phe Leu Trp Gly Leu Arg Ser Tyr His
625                 630                 635                 640

Glu Thr Ser Lys Met Lys Val Leu Arg Phe Ile Ala Glu Val Gln Lys
                645                 650                 655

Arg Asp Pro Arg Asp Trp Thr Ala Gln Phe Met Glu Ala Ala Asp Glu
            660                 665                 670

Ala Leu Asp Ala Leu Asp Ala Ala Ala Ala Glu Ala Glu Ala Arg Ala
        675                 680                 685

Glu Ala Arg Thr Arg Met Gly Ile Gly Asp Glu Ala Val Ser Gly Pro
    690                 695                 700

Trp Ser Trp Asp Asp Ile Glu Phe Glu Leu Leu Thr Trp Asp Glu Glu
705                 710                 715                 720

Gly Asp Phe Gly Asp Pro Trp Ser Arg Ile Pro Phe Thr Phe Trp Ala
                725                 730                 735

Arg Tyr His Gln Asn Ala Arg Ser Arg Phe Pro Gln Thr Phe Ala Gly
            740                 745                 750

Pro Ile Ile Gly Pro Gly Gly Thr Ala Ser Ala Asn Phe Ala Ala Asn
        755                 760                 765

Phe Gly Ala Ile Gly Phe Phe Trp Val Glu 
    770                 775



<210> 2573
<211> 103
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2573
Met Gly Phe Thr Arg Phe Ser Leu Leu Cys Xaa Gly Xaa Ala Lys Leu
  1               5                  10                  15

Lys Tyr Pro Tyr Xaa Trp Ser Thr Pro Val Lys Gly Ser Glu Phe Phe
             20                  25                  30

Ser Ala Tyr Arg Lys Ile Asn Gln Thr Gly Ser Ile Ser Arg Val Ser
         35                  40                  45

Ser Val Gln Glu Glu Phe Leu Lys Leu Leu Ser Ala Thr Cys Val Phe
     50                  55                  60

Leu Gly Ile Cys Pro Cys Val Thr Leu Gln Thr Ser Thr Leu Gly Ser
 65                  70                  75                  80

Pro Gly Ser Ala Ser Asn Gln Arg Ser Ser Leu Ala Ala Ala Glu Leu
                 85                  90                  95

Pro Ile Ser Lys Val Asp Thr 
            100



<210> 2574
<211> 317
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (115)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (226)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (241)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (242)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (246)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (275)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2574
Met Ala Ser Ala Asp Glu Leu Thr Phe His Glu Phe Glu Glu Ala Thr
  1               5                  10                  15

Asn Leu Leu Ala Asp Thr Pro Asp Ala Ala Thr Thr Ser Arg Ser Asp
             20                  25                  30

Gln Leu Thr Pro Gln Gly His Val Ala Val Ala Val Gly Ser Gly Gly
         35                  40                  45

Ser Tyr Gly Ala Glu Asp Glu Val Glu Glu Glu Ser Asp Lys Ala Ala
     50                  55                  60

Leu Leu Gln Glu Gln Gln Gln Gln Gln Gln Pro Gly Phe Trp Thr Phe
 65                  70                  75                  80

Ser Tyr Tyr Gln Ser Phe Phe Asp Val Asp Thr Ser Gln Val Leu Asp
                 85                  90                  95

Arg Ile Lys Gly Ser Leu Leu Pro Arg Pro Gly His Asn Phe Val Arg
            100                 105                 110

His His Xaa Arg Asn Arg Pro Asp Leu Tyr Gly Pro Phe Trp Ile Cys
        115                 120                 125

Ala Thr Leu Ala Phe Val Leu Ala Val Thr Gly Asn Leu Thr Leu Val
    130                 135                 140

Leu Ala Gln Arg Arg Asp Pro Ser Ile His Tyr Ser Pro Gln Phe His
145                 150                 155                 160

Lys Val Thr Val Ala Gly Ile Ser Ile Tyr Cys Tyr Thr Trp Leu Val
                165                 170                 175

Pro Leu Ala Leu Trp Gly Phe Leu Arg Trp Arg Lys Gly Val Gln Glu
            180                 185                 190

Arg Met Gly Pro Tyr Thr Phe Leu Glu Thr Val Cys Ile Tyr Gly Tyr
        195                 200                 205

Ser Leu Phe Val Phe Ile Pro Met Val Val Leu Trp Leu Ile Pro Cys
    210                 215                 220

Ala Xaa Gly Tyr Ser Gly Ser Leu Gly Ala Leu Ala Leu Gly Leu Ser
225                 230                 235                 240

Xaa Xaa Gly Leu Val Xaa Thr Leu Trp Pro Val Val Arg Glu Asp Thr
                245                 250                 255

Arg Leu Val Ala Thr Val Leu Leu Ser Val Val Val Leu Leu His Ala
            260                 265                 270

Leu Leu Xaa Met Gly Cys Lys Leu Tyr Phe Phe Gln Ser Leu Pro Pro
        275                 280                 285

Glu Asn Val Ala Pro Pro Pro Gln Ile Thr Ser Leu Pro Ser Asn Ile
    290                 295                 300

Ala Leu Ser Pro Thr Leu Pro Gln Ser Leu Ala Pro Ser 
305                 310                 315



<210> 2575
<211> 182
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (69)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2575
Met Leu Leu Glu Ala Leu Tyr Leu Phe Leu Thr Ala Arg Asn Leu Thr
  1               5                  10                  15

Val Val Asn Tyr Ser Ser Ile Asn Arg Phe Met Lys Lys Leu Met Phe
             20                  25                  30

Pro Val Gly Tyr Gly Val Pro Ala Val Thr Val Ala Ile Ser Ala Ala
         35                  40                  45

Ser Arg Pro His Leu Tyr Gly Thr Pro Ser Arg Cys Trp Leu Gln Pro
     50                  55                  60

Glu Lys Gly Xaa Xaa Trp Gly Phe Leu Gly Pro Xaa Cys Ala Ile Phe
 65                  70                  75                  80

Ser Val Asn Leu Val Leu Phe Leu Val Thr Leu Trp Ile Leu Lys Asn
                 85                  90                  95

Arg Leu Ser Ser Leu Asn Ser Glu Val Ser Thr Leu Arg Asn Thr Arg
            100                 105                 110

Met Leu Ala Phe Lys Ala Thr Val Ser Cys Ser Ser Trp Ala Ala Arg
        115                 120                 125

Gly Val Trp Ala Ser Cys Arg Trp Val Arg Leu Pro Gly Ser Trp Pro
    130                 135                 140

Thr Ser Ser Pro Ser Ser Thr Ala Cys Arg Val Ser Ser Ser Ser Trp
145                 150                 155                 160

Cys Thr Ala Ser Ser Ala Ser Arg Ser Gly Ser Asn Met Gly Asn Gly
                165                 170                 175

Pro Lys Gly Ser Gly Asn 
            180



<210> 2576
<211> 162
<212> PRT
<213> Homo sapiens

<400> 2576
Met Leu Arg Ala Val Gly Ser Leu Leu Arg Leu Gly Arg Gly Leu Thr
  1               5                  10                  15

Val Arg Cys Gly Pro Gly Ala Pro Leu Glu Ala Thr Arg Arg Pro Ala
             20                  25                  30

Pro Ala Leu Pro Pro Arg Gly Leu Pro Cys Tyr Ser Ser Gly Gly Ala
         35                  40                  45

Pro Ser Asn Ser Gly Pro Gln Gly His Gly Glu Ile His Arg Val Pro
     50                  55                  60

Thr Gln Arg Arg Pro Ser Gln Phe Asp Lys Lys Ile Leu Leu Trp Thr
 65                  70                  75                  80

Gly Arg Phe Lys Ser Met Glu Glu Ile Pro Pro Arg Ile Pro Pro Glu
                 85                  90                  95

Met Ile Asp Thr Ala Arg Asn Lys Ala Arg Val Lys Ala Cys Tyr Ile
            100                 105                 110

Met Ile Gly Leu Thr Ile Ile Ala Cys Phe Ala Val Ile Val Ser Ala
        115                 120                 125

Lys Arg Ala Val Glu Arg His Glu Ser Leu Thr Ser Trp Asn Leu Ala
    130                 135                 140

Lys Lys Ala Lys Trp Arg Glu Glu Ala Ala Leu Ala Ala Gln Ala Lys
145                 150                 155                 160

Ala Lys 




<210> 2577
<211> 213
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (199)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (208)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2577
Met Ala Asp Asp Ala Gly Leu Glu Thr Pro Leu Cys Ser Glu Gln Phe
  1               5                  10                  15

Gly Ser Gly Glu Ala Arg Gly Cys Arg Ala Ala Ala Asp Gly Ser Leu
             20                  25                  30

Gln Trp Glu Val Gly Gly Trp Arg Trp Trp Gly Leu Ser Arg Ala Phe
         35                  40                  45

Thr Val Lys Pro Glu Gly Arg Asp Ala Gly Glu Val Gly Ala Ser Gly
     50                  55                  60

Ala Pro Ser Pro Pro Leu Ser Gly Leu Gln Ala Val Phe Leu Pro Xaa
 65                  70                  75                  80

Gly Phe Pro Asp Ser Val Ser Pro Asp Tyr Leu Pro Tyr Gln Leu Trp
                 85                  90                  95

Asp Ser Val Gln Ala Phe Ala Ser Ser Leu Ser Gly Ser Leu Ala Thr
            100                 105                 110

Gln Ala Val Leu Leu Gly Ile Gly Val Gly Asn Ala Lys Ala Thr Val
        115                 120                 125

Ser Ala Ala Thr Ala Thr Trp Leu Val Lys Asp Ser Thr Gly Met Leu
    130                 135                 140

Gly Arg Ile Val Phe Ala Trp Trp Lys Gly Ser Lys Leu Asp Cys Asn
145                 150                 155                 160

Ala Lys Gln Trp Arg Leu Phe Ala Asp Ile Leu Asn Asp Val Ala Met
                165                 170                 175

Phe Leu Glu Ile Met Ala Pro Val Tyr Pro Ile Cys Phe Thr Met Thr
            180                 185                 190

Val Ser Thr Ser Asn Leu Xaa Lys Cys Ile Val Ser Val Ala Gly Xaa
        195                 200                 205

Ala Thr Arg Leu Pro 
    210



<210> 2578
<211> 131
<212> PRT
<213> Homo sapiens

<400> 2578
Met Pro Lys Ala Cys Thr Gly Leu Lys Val Val Met Arg His Glu Arg
  1               5                  10                  15

His Ser Ser Gln Ala Thr Gln Asp Ser Ile Tyr Pro Thr Phe Leu Arg
             20                  25                  30

Gln Gln Asn Ser Gly Asp Gly Ala Lys Val Ser Gly Gly Gln Gly Leu
         35                  40                  45

Gly Val Ala Met Lys Gly Trp Leu Pro Cys Asp Asp Ser Ile Cys Tyr
     50                  55                  60

Val Phe Pro Leu Trp Phe Ser Val Ser Met Phe Tyr Leu Ile Phe Phe
 65                  70                  75                  80

Glu Leu Cys His Pro Gly Trp Asn Gln Trp His Asp Leu Gly Ser Leu
                 85                  90                  95

Gln Pro Pro Pro Pro Gly Phe Lys Gln Phe Ser Cys Leu Ser Cys Pro
            100                 105                 110

Ser Ser Cys Asp Tyr Arg His Ala Pro Pro Cys Pro Ala Asn Phe Cys
        115                 120                 125

Thr Phe Phe 
    130



<210> 2579
<211> 374
<212> PRT
<213> Homo sapiens

<400> 2579
Met Arg Pro Gly Thr Ala Leu Gln Ala Val Leu Leu Ala Val Leu Leu
  1               5                  10                  15

Val Gly Leu Arg Ala Ala Thr Gly Arg Leu Leu Ser Gly Gln Pro Val
             20                  25                  30

Cys Arg Gly Gly Thr Gln Arg Pro Cys Tyr Lys Val Ile Tyr Phe His
         35                  40                  45

Asp Thr Ser Arg Arg Leu Asn Phe Glu Glu Ala Lys Glu Ala Cys Arg
     50                  55                  60

Arg Asp Gly Gly Gln Leu Val Ser Ile Glu Ser Glu Asp Glu Gln Lys
 65                  70                  75                  80

Leu Ile Glu Lys Phe Ile Glu Asn Leu Leu Pro Ser Asp Gly Asp Phe
                 85                  90                  95

Trp Ile Gly Leu Arg Arg Arg Glu Glu Lys Gln Ser Asn Ser Thr Ala
            100                 105                 110

Cys Gln Asp Leu Tyr Ala Trp Thr Asp Gly Ser Ile Ser Gln Phe Arg
        115                 120                 125

Asn Trp Tyr Val Asp Glu Pro Ser Cys Gly Ser Glu Val Cys Val Val
    130                 135                 140

Met Tyr His Gln Pro Ser Ala Pro Ala Gly Ile Gly Gly Pro Tyr Met
145                 150                 155                 160

Phe Gln Trp Asn Asp Asp Arg Cys Asn Met Lys Asn Asn Phe Ile Cys
                165                 170                 175

Lys Tyr Ser Asp Glu Lys Pro Ala Val Pro Ser Arg Glu Ala Glu Gly
            180                 185                 190

Glu Glu Thr Glu Leu Thr Thr Pro Val Leu Pro Glu Glu Thr Gln Glu
        195                 200                 205

Glu Asp Ala Lys Lys Thr Phe Lys Glu Ser Arg Glu Ala Ala Leu Asn
    210                 215                 220

Leu Ala Tyr Ile Leu Ile Pro Ser Ile Pro Leu Leu Leu Leu Leu Val
225                 230                 235                 240

Val Thr Thr Val Val Cys Trp Val Trp Ile Cys Arg Lys Arg Lys Arg
                245                 250                 255

Glu Gln Pro Asp Pro Ser Thr Lys Lys Gln His Thr Ile Trp Pro Ser
            260                 265                 270

Pro His Gln Gly Asn Ser Pro Asp Leu Glu Val Tyr Asn Val Ile Arg
        275                 280                 285

Lys Gln Ser Glu Ala Asp Leu Ala Glu Thr Arg Pro Asp Leu Lys Asn
    290                 295                 300

Ile Ser Phe Arg Val Cys Ser Gly Glu Ala Thr Pro Asp Asp Met Ser
305                 310                 315                 320

Cys Asp Tyr Asp Asn Met Ala Val Asn Pro Ser Glu Ser Gly Phe Val
                325                 330                 335

Thr Leu Val Ser Val Glu Ser Gly Phe Val Thr Asn Asp Ile Tyr Glu
            340                 345                 350

Phe Ser Pro Asp Gln Met Gly Arg Ser Lys Glu Ser Gly Trp Val Glu
        355                 360                 365

Asn Glu Ile Tyr Gly Tyr 
    370



<210> 2580
<211> 167
<212> PRT
<213> Homo sapiens

<400> 2580
Met Glu Ser Asn Leu Ser Gly Leu Val Pro Ala Ala Gly Leu Val Pro
  1               5                  10                  15

Ala Leu Pro Pro Ala Val Thr Leu Gly Leu Thr Ala Ala Tyr Thr Thr
             20                  25                  30

Leu Tyr Ala Leu Leu Phe Phe Ser Val Tyr Ala Gln Leu Trp Leu Val
         35                  40                  45

Leu Leu Tyr Gly His Lys Arg Leu Ser Tyr Gln Thr Val Phe Leu Ala
     50                  55                  60

Leu Cys Leu Leu Trp Ala Ala Leu Arg Thr Thr Leu Phe Ser Phe Tyr
 65                  70                  75                  80

Phe Arg Asp Thr Pro Arg Ala Asn Arg Leu Gly Pro Leu Pro Phe Trp
                 85                  90                  95

Leu Leu Tyr Cys Cys Pro Val Cys Leu Gln Phe Phe Thr Leu Thr Leu
            100                 105                 110

Met Asn Leu Tyr Phe Ala Gln Val Val Phe Lys Ala Lys Val Lys Arg
        115                 120                 125

Arg Pro Glu Met Ser Arg Gly Phe Gly Ser Gln Gly Val Glu Glu Ala
    130                 135                 140

Gly Ser Leu Leu Ser Leu Arg Val Leu Cys Cys Tyr Leu Cys Gln Gly
145                 150                 155                 160

Thr Ser Val Cys Gln Ala Ala 
                165



<210> 2581
<211> 186
<212> PRT
<213> Homo sapiens

<400> 2581
Met Ala Val Ile Tyr Thr Lys Leu Tyr Cys Asn Leu Glu Lys Glu Asp
  1               5                  10                  15

Leu Ser Glu Asn Ser Gln Ser Ser Met Ile Lys His Val Ala Trp Leu
             20                  25                  30

Ile Phe Thr Asn Cys Ile Phe Phe Cys Pro Val Ala Phe Phe Ser Phe
         35                  40                  45

Ala Pro Leu Ile Thr Ala Ile Ser Ile Ser Pro Glu Ile Met Lys Ser
     50                  55                  60

Val Thr Leu Ile Phe Phe Pro Leu Pro Ala Cys Leu Asn Pro Val Leu
 65                  70                  75                  80

Tyr Val Phe Phe Asn Pro Lys Phe Lys Glu Asp Trp Lys Leu Leu Lys
                 85                  90                  95

Arg Arg Val Thr Lys Lys Ser Gly Ser Val Ser Val Ser Ile Ser Ser
            100                 105                 110

Gln Gly Gly Cys Leu Glu Gln Asp Phe Tyr Tyr Asp Cys Gly Met Tyr
        115                 120                 125

Ser His Leu Gln Gly Asn Leu Thr Val Cys Asp Cys Cys Glu Ser Phe
    130                 135                 140

Leu Leu Thr Lys Pro Val Ser Cys Lys His Leu Ile Lys Ser His Ser
145                 150                 155                 160

Cys Pro Ala Leu Ala Val Ala Ser Cys Gln Arg Pro Glu Gly Tyr Trp
                165                 170                 175

Ser Asp Cys Gly Thr Gln Cys Gly Pro Leu 
            180                 185



<210> 2582
<211> 148
<212> PRT
<213> Homo sapiens

<400> 2582
Met Gly Thr Trp Trp His Arg Glu Thr Gln Leu Ala Thr Phe Ser Ala
  1               5                  10                  15

Thr Leu Leu Thr Gln Leu His Pro Thr Leu Leu Thr Gln Val His Pro
             20                  25                  30

Leu Leu Leu Ser Phe Pro Gln Arg Thr Gly Ser Arg Ala Trp Trp Val
         35                  40                  45

Phe Ala Thr Leu Gly Ala Ser Ser Ala Ala Pro His Leu Ser Leu Phe
     50                  55                  60

Ser Pro Lys Leu Val Phe Leu Thr Ile Ile Val Val Gly Gly Gly Gln
 65                  70                  75                  80

Met Leu Lys Val Glu Ala Asp Leu Glu Lys Glu Thr His Gly Val Thr
                 85                  90                  95

Val Ala Lys Asp Ser Trp Lys Arg Asn Ser Ile Thr Ser Ser Leu Ala
            100                 105                 110

Thr Thr Arg His Leu Arg Pro Trp His Ser Gln Arg Leu Cys Ala Glu
        115                 120                 125

Pro Ser Leu Ser Thr Ser Ser Gly Pro Ala Ser Cys Ser Glu Val Ser
    130                 135                 140

Ala Val Arg Gln 
145



<210> 2583
<211> 345
<212> PRT
<213> Homo sapiens

<400> 2583
Met Lys Gly Glu Leu Leu Leu Phe Ser Ser Val Ile Val Leu Leu Gln
  1               5                  10                  15

Val Val Cys Ser Cys Pro Asp Lys Cys Tyr Cys Gln Ser Ser Thr Asn
             20                  25                  30

Phe Val Asp Cys Ser Gln Gln Gly Leu Ala Glu Ile Pro Ser His Leu
         35                  40                  45

Pro Pro Gln Thr Arg Thr Leu His Leu Gln Asp Asn Gln Ile His His
     50                  55                  60

Leu Pro Ala Phe Ala Phe Arg Ser Val Pro Trp Leu Met Thr Leu Asn
 65                  70                  75                  80

Leu Ser Asn Asn Ser Leu Ser Asn Leu Ala Pro Gly Ala Phe His Gly
                 85                  90                  95

Leu Gln His Leu Gln Val Leu Asn Leu Thr Gln Asn Ser Leu Leu Ser
            100                 105                 110

Leu Glu Ser Arg Leu Phe His Ser Leu Pro Gln Leu Arg Glu Leu Asp
        115                 120                 125

Leu Ser Ser Asn Asn Ile Ser His Leu Pro Thr Ser Leu Gly Glu Thr
    130                 135                 140

Trp Glu Asn Leu Thr Ile Leu Ala Val Gln Gln Asn Gln Leu Gln Gln
145                 150                 155                 160

Leu Asp Arg Ala Leu Leu Glu Ser Met Pro Ser Val Arg Leu Leu Leu
                165                 170                 175

Leu Lys Asp Asn Leu Trp Lys Cys Asn Cys His Leu Leu Gly Leu Lys
            180                 185                 190

Leu Trp Leu Glu Lys Phe Val Tyr Lys Gly Gly Leu Thr Asp Gly Ile
        195                 200                 205

Ile Cys Glu Ser Pro Asp Thr Trp Lys Gly Lys Asp Leu Leu Arg Ile
    210                 215                 220

Pro His Glu Leu Tyr Gln Pro Cys Pro Leu Pro Ala Pro Asp Pro Val
225                 230                 235                 240

Ser Ser Gln Ala Gln Trp Pro Gly Ser Ala His Gly Val Val Leu Arg
                245                 250                 255

Pro Pro Glu Asn His Asn Ala Gly Glu Arg Glu Leu Leu Glu Cys Glu
            260                 265                 270

Leu Lys Pro Lys Pro Arg Pro Ala Asn Leu Arg His Ala Ile Ala Thr
        275                 280                 285

Val Ile Ile Thr Gly Val Val Cys Gly Ile Val Cys Leu Met Met Leu
    290                 295                 300

Ala Ala Ala Ile Tyr Gly Cys Thr Tyr Ala Ala Ile Thr Ala Gln Tyr
305                 310                 315                 320

His Gly Gly Pro Leu Ala Gln Thr Asn Asp Pro Gly Lys Val Glu Glu
                325                 330                 335

Lys Glu Arg Phe Asp Ser Ser Pro Ala 
            340                 345



<210> 2584
<211> 109
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2584
Met Ile Met Gly Met Ile Ala Gln Asn Lys Lys Lys Ser Cys Leu Thr
  1               5                  10                  15

Thr Val Phe Tyr Arg Arg Asp Trp Glu Lys Ser Ser Cys Phe Leu Cys
             20                  25                  30

Asp Leu Ile Ser Glu Glu Thr Asp Pro Lys Ile Ile Thr Ala Gly Asn
         35                  40                  45

Leu Val His Leu Ala Leu Arg Phe Lys Cys Asn Gln Asn Cys Pro Gln
     50                  55                  60

Gly Pro Ala Ile Lys Ala Leu Ser Leu Xaa Thr Phe Trp Tyr Leu Val
 65                  70                  75                  80

Arg Glu Leu Phe Thr Val Arg Lys Cys Gly Lys Ile Ala Leu Cys Val
                 85                  90                  95

Cys Val Cys Val Cys Val Cys Asn Leu Leu Gly Trp Gly 
            100                 105



<210> 2585
<211> 333
<212> PRT
<213> Homo sapiens

<400> 2585
Met Leu Thr Glu Arg Arg Asn His Ala Arg Glu Leu Val Arg Ser Glu
  1               5                  10                  15

Glu Leu Gly Arg Trp Asp Ala Leu Val Val Met Ser Gly Asp Gly Leu
             20                  25                  30

Met His Glu Val Val Asn Gly Leu Met Glu Arg Pro Asp Trp Glu Thr
         35                  40                  45

Ala Ile Gln Lys Pro Leu Cys Ser Leu Pro Ala Gly Ser Gly Asn Ala
     50                  55                  60

Leu Ala Ala Ser Leu Asn His Tyr Ala Gly Tyr Glu Gln Val Thr Asn
 65                  70                  75                  80

Glu Asp Leu Leu Thr Asn Cys Thr Leu Leu Leu Cys Arg Arg Leu Leu
                 85                  90                  95

Ser Pro Met Asn Leu Leu Ser Leu His Thr Ala Ser Gly Leu Arg Leu
            100                 105                 110

Phe Ser Val Leu Ser Leu Ala Trp Gly Phe Ile Ala Asp Val Asp Leu
        115                 120                 125

Glu Ser Glu Lys Tyr Arg Arg Leu Gly Glu Met Arg Phe Thr Leu Gly
    130                 135                 140

Thr Phe Leu Arg Leu Ala Ala Leu Arg Thr Tyr Arg Gly Arg Leu Ala
145                 150                 155                 160

Tyr Leu Pro Val Gly Arg Val Gly Ser Lys Thr Pro Ala Ser Pro Val
                165                 170                 175

Val Val Gln Gln Gly Pro Val Asp Ala His Leu Val Pro Leu Glu Glu
            180                 185                 190

Pro Val Pro Ser His Trp Thr Val Val Pro Asp Glu Asp Phe Val Leu
        195                 200                 205

Val Leu Ala Leu Leu His Ser His Leu Gly Ser Glu Met Phe Ala Ala
    210                 215                 220

Pro Met Gly Arg Cys Ala Ala Gly Val Met His Leu Phe Tyr Val Arg
225                 230                 235                 240

Ala Gly Val Ser Arg Ala Met Leu Leu Arg Leu Phe Leu Ala Met Glu
                245                 250                 255

Lys Gly Arg His Met Glu Tyr Glu Cys Pro Tyr Leu Val Tyr Val Pro
            260                 265                 270

Val Val Ala Phe Arg Leu Glu Pro Lys Asp Gly Lys Gly Val Phe Ala
        275                 280                 285

Val Asp Gly Glu Leu Met Val Ser Glu Ala Val Gln Gly Gln Val His
    290                 295                 300

Pro Asn Tyr Phe Trp Met Val Ser Gly Cys Val Glu Pro Pro Pro Ser
305                 310                 315                 320

Trp Lys Pro Gln Gln Met Pro Pro Pro Glu Glu Pro Leu 
                325                 330



<210> 2586
<211> 314
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2586
Met Thr Ala Ala Ile Arg Arg Gln Arg Glu Leu Ser Ile Leu Pro Lys
  1               5                  10                  15

Val Thr Leu Glu Ala Met Asn Thr Thr Val Met Gln Gly Phe Asn Arg
             20                  25                  30

Ser Glu Arg Cys Pro Xaa Asp Thr Arg Ile Val Gln Leu Val Phe Pro
         35                  40                  45

Ala Leu Tyr Thr Val Val Phe Leu Thr Gly Ile Leu Leu Asn Thr Leu
     50                  55                  60

Ala Leu Trp Val Phe Val His Ile Pro Ser Ser Ser Thr Phe Ile Ile
 65                  70                  75                  80

Tyr Leu Lys Asn Thr Leu Val Ala Asp Leu Ile Met Thr Leu Met Leu
                 85                  90                  95

Pro Phe Lys Ile Leu Ser Asp Ser His Leu Ala Pro Trp Gln Leu Arg
            100                 105                 110

Ala Phe Val Cys Arg Phe Ser Ser Val Ile Phe Tyr Glu Thr Met Tyr
        115                 120                 125

Val Gly Ile Val Leu Leu Gly Leu Ile Ala Phe Asp Arg Phe Leu Lys
    130                 135                 140

Ile Ile Arg Pro Leu Arg Asn Ile Phe Leu Lys Lys Pro Val Phe Ala
145                 150                 155                 160

Lys Thr Val Ser Ile Phe Ile Trp Phe Phe Leu Phe Phe Ile Ser Leu
                165                 170                 175

Pro Asn Met Ile Leu Ser Asn Lys Glu Ala Thr Pro Ser Ser Val Lys
            180                 185                 190

Lys Cys Ala Ser Leu Lys Gly Pro Leu Gly Leu Lys Trp His Gln Met
        195                 200                 205

Val Asn Asn Ile Cys Gln Phe Ile Phe Trp Thr Val Phe Ile Leu Met
    210                 215                 220

Leu Val Phe Tyr Val Val Ile Ala Lys Lys Tyr Met Ile Leu Ile Glu
225                 230                 235                 240

Ser Pro Lys Val Arg Thr Glu Lys Thr Thr Lys Ser Trp Lys Ala Lys
                245                 250                 255

Tyr Leu Leu Ser Trp Leu Ser Ser Leu Cys Val Leu Leu His Phe Ile
            260                 265                 270

Ser Pro Glu Phe His Ile Leu Thr Val Lys Pro Thr Ile Arg Leu Thr
        275                 280                 285

Val Asp Cys Lys Ile Asn Cys Leu Leu Leu Lys Lys Gln Leu Ser Phe
    290                 295                 300

Trp Gln Gln Leu Thr Phe Val Trp Ile Pro 
305                 310



<210> 2587
<211> 324
<212> PRT
<213> Homo sapiens

<400> 2587
Met Ala Ala Ala Ala Pro Gly Asn Gly Arg Ala Ser Ala Pro Arg Leu
  1               5                  10                  15

Leu Leu Leu Phe Leu Val Pro Leu Leu Trp Ala Pro Ala Ala Val Arg
             20                  25                  30

Ala Gly Pro Asp Glu Asp Leu Ser His Arg Asn Lys Glu Pro Pro Ala
         35                  40                  45

Pro Ala Gln Gln Leu Gln Pro Gln Pro Val Ala Val Gln Gly Pro Glu
     50                  55                  60

Pro Ala Arg Val Glu Lys Ile Phe Thr Pro Ala Ala Pro Val His Thr
 65                  70                  75                  80

Asn Lys Glu Asp Pro Ala Thr Gln Thr Asn Leu Gly Phe Ile His Ala
                 85                  90                  95

Phe Val Ala Ala Ile Ser Val Ile Ile Val Ser Glu Leu Gly Asp Lys
            100                 105                 110

Thr Phe Phe Ile Ala Ala Ile Met Ala Met Arg Tyr Asn Arg Leu Thr
        115                 120                 125

Val Leu Ala Gly Ala Met Leu Ala Leu Gly Leu Met Thr Cys Leu Ser
    130                 135                 140

Val Leu Phe Gly Tyr Ala Thr Thr Val Ile Pro Arg Val Tyr Thr Tyr
145                 150                 155                 160

Tyr Val Ser Thr Val Leu Phe Ala Ile Phe Gly Ile Arg Met Leu Arg
                165                 170                 175

Glu Gly Leu Lys Met Ser Pro Asp Glu Gly Gln Glu Glu Leu Glu Glu
            180                 185                 190

Val Gln Ala Glu Leu Lys Lys Lys Asp Glu Glu Phe Gln Arg Thr Lys
        195                 200                 205

Leu Leu Asn Gly Pro Gly Asp Val Glu Thr Gly Thr Ser Ile Thr Val
    210                 215                 220

Pro Gln Lys Lys Trp Leu His Phe Ile Ser Pro Ile Phe Val Gln Ala
225                 230                 235                 240

Leu Thr Leu Thr Phe Leu Ala Glu Trp Gly Asp Arg Ser Gln Leu Thr
                245                 250                 255

Thr Ile Val Leu Ala Ala Arg Glu Asp Pro Tyr Gly Val Ala Val Gly
            260                 265                 270

Gly Thr Val Gly His Cys Leu Cys Thr Gly Leu Ala Val Ile Gly Gly
        275                 280                 285

Arg Met Ile Ala Gln Lys Ile Ser Val Arg Thr Val Thr Ile Ile Gly
    290                 295                 300

Gly Ile Val Phe Leu Ala Phe Ala Phe Ser Ala Leu Phe Ile Ser Pro
305                 310                 315                 320

Asp Ser Gly Phe 




<210> 2588
<211> 148
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (109)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2588
Met Asp Phe Leu Val Leu Phe Leu Phe Tyr Leu Ala Ser Val Leu Met
  1               5                  10                  15

Gly Leu Val Leu Ile Cys Val Cys Ser Lys Thr His Ser Leu Lys Gly
             20                  25                  30

Leu Ala Arg Gly Gly Ala Gln Ile Phe Ser Cys Ile Ile Pro Glu Cys
         35                  40                  45

Leu Gln Arg Ala Val His Gly Leu Leu His Tyr Leu Phe His Thr Arg
     50                  55                  60

Asn His Thr Phe Ile Val Leu His Leu Val Leu Gln Gly Met Val Tyr
 65                  70                  75                  80

Thr Glu Tyr Thr Trp Glu Val Phe Gly Tyr Cys Gln Glu Leu Glu Leu
                 85                  90                  95

Ser Leu His Tyr Leu Leu Leu Pro Tyr Leu Leu Leu Xaa Val Asn Leu
            100                 105                 110

Phe Phe Phe Thr Leu Thr Cys Gly Thr Asn Pro Gly Ile Ile Thr Lys
        115                 120                 125

Ala Asn Glu Leu Leu Phe Leu His Val Tyr Glu Phe Asp Glu Val Met
    130                 135                 140

Phe Gln Arg Thr 
145



<210> 2589
<211> 177
<212> PRT
<213> Homo sapiens

<400> 2589
Met Ala Leu Ser Tyr Ala Ile Ser Ser Pro Leu Phe Gly Leu Leu Ser
  1               5                  10                  15

Asp Lys Arg Pro Pro Leu Arg Lys Trp Leu Leu Val Phe Gly Asn Leu
             20                  25                  30

Ile Thr Ala Gly Cys Tyr Met Leu Leu Gly Pro Val Pro Ile Leu His
         35                  40                  45

Ile Lys Ser Gln Leu Trp Leu Leu Val Leu Ile Leu Val Val Ser Gly
     50                  55                  60

Leu Ser Ala Gly Met Ser Ile Ile Pro Thr Phe Pro Glu Ile Leu Ser
 65                  70                  75                  80

Cys Ala His Glu Asn Gly Phe Glu Glu Gly Leu Ser Thr Leu Gly Leu
                 85                  90                  95

Val Ser Gly Leu Phe Ser Ala Met Trp Ser Ile Gly Ala Phe Met Gly
            100                 105                 110

Pro Thr Leu Gly Gly Phe Leu Tyr Glu Lys Ile Gly Phe Glu Trp Ala
        115                 120                 125

Ala Ala Ile Gln Gly Leu Trp Ala Leu Ile Ser Gly Leu Ala Met Gly
    130                 135                 140

Leu Phe Tyr Leu Leu Glu Tyr Ser Arg Arg Lys Arg Ser Lys Ser Gln
145                 150                 155                 160

Asn Ile Leu Ser Thr Glu Glu Glu Arg Thr Thr Leu Leu Pro Asn Glu
                165                 170                 175

Thr 




<210> 2590
<211> 447
<212> PRT
<213> Homo sapiens

<400> 2590
Met Leu Asn Ser Ile Leu Val Ile Leu Cys Leu Ile Ala Val Ser Ala
  1               5                  10                  15

Phe Phe Ser Met Ser Glu Ile Ser Leu Ala Ala Ser Arg Lys Ile Lys
             20                  25                  30

Leu Lys Leu Leu Ala Asp Glu Gly Asn Ile Asn Ala Gln Arg Val Leu
         35                  40                  45

Asn Met Gln Glu Asn Pro Gly Met Phe Phe Thr Val Val Gln Ile Gly
     50                  55                  60

Leu Asn Ala Val Ala Ile Leu Gly Gly Ile Val Gly Asp Ala Ala Phe
 65                  70                  75                  80

Ser Pro Ala Phe His Ser Leu Phe Ser Arg Tyr Met Ser Ala Glu Leu
                 85                  90                  95

Ser Glu Gln Leu Ser Phe Ile Leu Ser Phe Ser Leu Val Thr Gly Met
            100                 105                 110

Phe Ile Leu Phe Ala Asp Leu Thr Pro Lys Arg Ile Gly Met Ile Ala
        115                 120                 125

Pro Glu Ala Val Ala Leu Arg Ile Ile Asn Pro Met Arg Phe Cys Leu
    130                 135                 140

Tyr Val Cys Thr Pro Leu Val Trp Phe Phe Asn Gly Leu Ala Asn Ile
145                 150                 155                 160

Ile Phe Arg Ile Phe Lys Leu Pro Met Val Arg Lys Asp Asp Ile Thr
                165                 170                 175

Ser Asp Asp Ile Tyr Ala Val Val Glu Ala Gly Ala Leu Ala Gly Val
            180                 185                 190

Leu Arg Lys Gln Glu His Glu Leu Ile Glu Asn Val Phe Glu Leu Glu
        195                 200                 205

Ser Arg Thr Val Pro Ser Ser Met Thr Pro Arg Glu Asn Val Ile Trp
    210                 215                 220

Phe Asp Leu His Glu Asp Glu Gln Ser Leu Lys Asn Lys Val Ala Glu
225                 230                 235                 240

His Pro His Ser Lys Phe Leu Val Cys Asn Glu Asp Ile Asp His Ile
                245                 250                 255

Ile Gly Tyr Val Asp Ser Lys Asp Leu Leu Asn Arg Val Leu Ala Asn
            260                 265                 270

Gln Ser Leu Ala Leu Asn Ser Gly Val Gln Ile Arg Asn Thr Leu Ile
        275                 280                 285

Val Pro Asp Thr Leu Thr Leu Ser Glu Ala Leu Glu Ser Phe Lys Thr
    290                 295                 300

Ala Gly Glu Asp Phe Ala Val Ile Met Asn Glu Tyr Ala Leu Val Val
305                 310                 315                 320

Gly Ile Ile Thr Leu Asn Asp Val Met Thr Thr Leu Met Gly Asp Leu
                325                 330                 335

Val Gly Gln Gly Leu Glu Glu Gln Ile Val Ala Arg Asp Glu Asn Ser
            340                 345                 350

Trp Leu Ile Asp Gly Gly Thr Pro Ile Asp Asp Val Met Arg Val Leu
        355                 360                 365

Asp Ile Asp Glu Phe Pro Gln Ser Gly Asn Tyr Glu Thr Ile Gly Gly
    370                 375                 380

Phe Met Met Phe Met Leu Arg Lys Ile Pro Lys Arg Thr Asp Ser Val
385                 390                 395                 400

Lys Phe Ala Gly Tyr Lys Phe Glu Val Val Asp Ile Asp Asn Tyr Arg
                405                 410                 415

Ile Asp Gln Leu Leu Val Thr Arg Ile Asp Ser Lys Ala Thr Ala Leu
            420                 425                 430

Ser Pro Lys Leu Pro Asp Ala Lys Asp Lys Glu Glu Ser Val Ala 
        435                 440                 445



<210> 2591
<211> 348
<212> PRT
<213> Homo sapiens

<400> 2591
Met Leu Cys Pro Trp Arg Thr Ala Asn Leu Gly Leu Leu Leu Ile Leu
  1               5                  10                  15

Thr Ile Phe Leu Val Ala Glu Ala Glu Gly Ala Ala Gln Pro Asn Asn
             20                  25                  30

Ser Leu Met Leu Gln Thr Ser Lys Glu Asn His Ala Leu Ala Ser Ser
         35                  40                  45

Ser Leu Cys Met Asp Glu Lys Gln Ile Thr Gln Asn Tyr Ser Lys Val
     50                  55                  60

Leu Ala Glu Val Asn Thr Ser Trp Pro Val Lys Met Ala Thr Asn Ala
 65                  70                  75                  80

Val Leu Cys Cys Pro Pro Ile Ala Leu Arg Asn Leu Ile Ile Ile Thr
                 85                  90                  95

Trp Glu Ile Ile Leu Arg Gly Gln Pro Ser Cys Thr Lys Ala Tyr Lys
            100                 105                 110

Lys Glu Thr Asn Glu Thr Lys Glu Thr Asn Cys Thr Asp Glu Arg Ile
        115                 120                 125

Thr Trp Val Ser Arg Pro Asp Gln Asn Ser Asp Leu Gln Ile Arg Thr
    130                 135                 140

Val Ala Ile Thr His Asp Gly Tyr Tyr Arg Cys Ile Met Val Thr Pro
145                 150                 155                 160

Asp Gly Asn Phe His Arg Gly Tyr His Leu Gln Val Leu Val Thr Pro
                165                 170                 175

Glu Val Thr Leu Phe Gln Asn Arg Asn Arg Thr Ala Val Cys Lys Ala
            180                 185                 190

Val Ala Gly Lys Pro Ala Ala His Ile Ser Trp Ile Pro Glu Gly Asp
        195                 200                 205

Cys Ala Thr Lys Gln Glu Tyr Trp Ser Asn Gly Thr Val Thr Val Lys
    210                 215                 220

Ser Thr Cys His Trp Glu Val His Asn Val Ser Thr Val Asn Cys His
225                 230                 235                 240

Val Ser His Leu Thr Gly Asn Lys Ser Leu Tyr Ile Glu Leu Leu Pro
                245                 250                 255

Val Pro Gly Ala Lys Lys Ser Ala Lys Leu Tyr Ile Pro Tyr Ile Ile
            260                 265                 270

Leu Thr Ile Ile Ile Leu Thr Ile Val Gly Phe Ile Trp Leu Leu Lys
        275                 280                 285

Val Asn Gly Cys Arg Lys Tyr Lys Leu Asn Lys Thr Glu Ser Thr Pro
    290                 295                 300

Val Val Glu Glu Asp Glu Met Gln Pro Tyr Ala Ser Tyr Thr Glu Lys
305                 310                 315                 320

Asn Asn Pro Leu Tyr Asp Thr Thr Asn Lys Val Lys Ala Ser Glu Ala
                325                 330                 335

Leu Gln Ser Glu Val Asp Thr Asp Leu His Thr Leu 
            340                 345



<210> 2592
<211> 222
<212> PRT
<213> Homo sapiens

<400> 2592
Met Ala Trp Ile Met Pro Ile Ser Val Ala Leu Ser Thr Phe Gly Gly
  1               5                  10                  15

Val Asn Gly Ser Leu Phe Thr Ser Ser Arg Leu Phe Phe Ala Gly Ala
             20                  25                  30

Arg Glu Gly His Leu Pro Ser Val Leu Ala Met Ile His Val Lys Arg
         35                  40                  45

Cys Thr Pro Ile Pro Ala Leu Leu Phe Thr Cys Ile Ser Thr Leu Leu
     50                  55                  60

Met Leu Val Thr Ser Asp Met Tyr Thr Leu Ile Asn Tyr Val Gly Phe
 65                  70                  75                  80

Ile Asn Tyr Leu Phe Tyr Gly Val Thr Val Ala Gly Gln Ile Val Leu
                 85                  90                  95

Arg Trp Lys Lys Pro Asp Ile Pro Arg Pro Ile Lys Ile Asn Leu Leu
            100                 105                 110

Phe Pro Ile Ile Tyr Leu Leu Phe Trp Ala Phe Leu Leu Val Phe Ser
        115                 120                 125

Leu Trp Ser Glu Pro Val Val Cys Gly Ile Gly Leu Ala Ile Met Leu
    130                 135                 140

Thr Gly Val Pro Val Tyr Phe Leu Gly Val Tyr Trp Gln His Lys Pro
145                 150                 155                 160

Lys Cys Phe Ser Asp Phe Ile Glu Leu Leu Thr Leu Val Ser Gln Lys
                165                 170                 175

Met Cys Val Val Val Tyr Pro Glu Val Glu Arg Gly Ser Gly Thr Glu
            180                 185                 190

Glu Ala Asn Glu Asp Met Glu Glu Gln Gln Gln Pro Met Tyr Gln Pro
        195                 200                 205

Thr Pro Thr Lys Asp Lys Asp Val Ala Gly Gln Pro Gln Pro 
    210                 215                 220



<210> 2593
<211> 409
<212> PRT
<213> Homo sapiens

<400> 2593
Met Leu Ala Leu Val Met Val Gly Ser Ala Leu Val Ile Ala Leu Gly
  1               5                  10                  15

Leu Gly Lys Leu Phe Gly Trp Asp Ile Gly Leu Thr Ala Gly Met Leu
             20                  25                  30

Ala Gly Ser Met Thr Ser Thr Pro Val Leu Val Gly Ala Gly Asp Thr
         35                  40                  45

Leu Arg His Ser Gly Met Glu Ser Arg Gln Leu Ser Leu Ala Leu Asp
     50                  55                  60

Asn Leu Ser Leu Gly Tyr Ala Leu Thr Tyr Leu Ile Gly Leu Val Ser
 65                  70                  75                  80

Leu Ile Val Gly Ala Arg Tyr Leu Pro Lys Leu Gln His Gln Asp Leu
                 85                  90                  95

Gln Thr Ser Ala Gln Gln Ile Ala Arg Glu Arg Gly Leu Asp Thr Asp
            100                 105                 110

Ala Asn Arg Lys Val Tyr Leu Pro Val Ile Arg Ala Tyr Arg Val Gly
        115                 120                 125

Pro Glu Leu Val Ala Trp Thr Asp Gly Lys Asn Leu Arg Glu Leu Gly
    130                 135                 140

Ile Tyr Arg Gln Thr Gly Cys Tyr Ile Glu Arg Ile Arg Arg Asn Gly
145                 150                 155                 160

Ile Leu Ala Asn Pro Asp Gly Asp Ala Val Leu Gln Met Gly Asp Glu
                165                 170                 175

Ile Ala Leu Val Gly Tyr Pro Asp Ala His Ala Arg Leu Asp Pro Ser
            180                 185                 190

Phe Arg Asn Gly Lys Glu Val Phe Asp Arg Asp Leu Leu Asp Met Arg
        195                 200                 205

Ile Val Thr Glu Glu Val Val Val Lys Asn His Asn Ala Val Gly Lys
    210                 215                 220

Arg Leu Ala Gln Leu Lys Leu Thr Asp His Gly Cys Phe Leu Asn Arg
225                 230                 235                 240

Val Ile Arg Ser Gln Ile Glu Met Pro Ile Asp Asp Asn Val Val Leu
                245                 250                 255

Asn Lys Gly Asp Val Leu Gln Val Ser Gly Asp Ala Arg Arg Val Lys
            260                 265                 270

Thr Ile Ala Asp Arg Ile Gly Phe Ile Ser Ile His Ser Gln Val Thr
        275                 280                 285

Asp Leu Leu Ala Phe Cys Ala Phe Phe Val Ile Gly Leu Met Ile Gly
    290                 295                 300

Met Ile Thr Phe Gln Phe Ser Thr Phe Ser Phe Gly Met Gly Asn Ala
305                 310                 315                 320

Ala Gly Leu Leu Phe Ala Gly Ile Met Leu Gly Phe Met Arg Ala Asn
                325                 330                 335

His Pro Thr Phe Gly Tyr Ile Pro Gln Gly Ala Leu Ser Met Val Lys
            340                 345                 350

Glu Phe Gly Leu Met Val Phe Met Ala Gly Val Gly Leu Ser Ala Gly
        355                 360                 365

Ser Gly Ile Asn Asn Gly Leu Gly Ala Ile Gly Gly Gln Met Leu Ile
    370                 375                 380

Ala Gly Leu Ile Val Ser Leu Val Pro Val Ala Gly Ala Ser Thr Glu
385                 390                 395                 400

Ser Arg Arg Gly Cys Leu Gly Gly Arg 
                405



<210> 2594
<211> 328
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (319)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (326)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (327)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2594
Met Gly Pro Arg Ile Gly Pro Ala Gly Glu Val Pro Gln Val Pro Asp
  1               5                  10                  15

Lys Glu Thr Lys Ala Thr Met Gly Thr Glu Asn Thr Pro Gly Gly Lys
             20                  25                  30

Ala Ser Pro Asp Pro Gln Asp Val Arg Pro Ser Val Phe His Asn Ile
         35                  40                  45

Lys Leu Phe Val Leu Cys His Ser Leu Leu Gln Leu Ala Gln Leu Met
     50                  55                  60

Ile Ser Gly Tyr Leu Lys Ser Ser Ile Ser Thr Val Glu Lys Arg Phe
 65                  70                  75                  80

Gly Leu Ser Ser Gln Thr Ser Gly Leu Leu Ala Ser Phe Asn Glu Val
                 85                  90                  95

Gly Asn Thr Ala Leu Ile Val Phe Val Ser Tyr Phe Gly Ser Arg Val
            100                 105                 110

His Arg Pro Arg Met Ile Gly Tyr Gly Ala Ile Leu Val Ala Leu Ala
        115                 120                 125

Gly Leu Leu Met Thr Leu Pro His Phe Ile Ser Glu Pro Tyr Arg Tyr
    130                 135                 140

Asp Asn Thr Ser Pro Glu Asp Met Pro Gln Asp Phe Lys Ala Ser Leu
145                 150                 155                 160

Cys Leu Pro Thr Thr Ser Ala Pro Ala Ser Ala Pro Ser Asn Gly Asn
                165                 170                 175

Cys Ser Ser Tyr Thr Glu Thr Gln His Leu Ser Val Val Gly Ile Met
            180                 185                 190

Phe Val Ala Gln Thr Leu Leu Gly Val Gly Gly Val Pro Ile Gln Pro
        195                 200                 205

Phe Gly Ile Ser Tyr Ile Asp Asp Phe Ala His Asn Ser Asn Ser Pro
    210                 215                 220

Leu Tyr Leu Gly Ile Leu Phe Ala Val Thr Met Met Gly Pro Gly Leu
225                 230                 235                 240

Ala Phe Gly Leu Gly Ser Leu Met Leu Arg Leu Tyr Val Asp Ile Asn
                245                 250                 255

Gln Met Pro Glu Gly Gly Ile Ser Leu Thr Ile Lys Asp Pro Arg Trp
            260                 265                 270

Val Gly Ala Trp Trp Leu Gly Phe Leu Ile Ala Ala Gly Ala Val Ala
        275                 280                 285

Leu Ala Ala Ile Pro Tyr Phe Phe Phe Pro Lys Glu Met Pro Lys Glu
    290                 295                 300

Lys Val Ser Phe Ile Ser Ala Lys Gly Leu Ser Ser His Arg Xaa Thr
305                 310                 315                 320

Ala Arg Lys Gly Arg Xaa Xaa Leu 
                325



<210> 2595
<211> 309
<212> PRT
<213> Homo sapiens

<400> 2595
Met Ala Ala Glu Trp Ala Ser Arg Phe Trp Leu Trp Ala Thr Leu Leu
  1               5                  10                  15

Ile Pro Ala Ala Ala Val Tyr Glu Asp Gln Val Gly Lys Phe Asp Trp
             20                  25                  30

Arg Gln Gln Tyr Val Gly Lys Val Lys Phe Ala Ser Leu Glu Phe Ser
         35                  40                  45

Pro Gly Ser Lys Lys Leu Val Val Ala Thr Glu Lys Asn Val Ile Ala
     50                  55                  60

Ala Leu Asn Ser Arg Thr Gly Glu Ile Leu Trp Arg His Val Asp Lys
 65                  70                  75                  80

Gly Thr Ala Glu Gly Ala Val Asp Ala Met Leu Leu His Gly Gln Asp
                 85                  90                  95

Val Ile Thr Val Ser Asn Gly Gly Arg Ile Met Arg Ser Trp Glu Thr
            100                 105                 110

Asn Ile Gly Gly Leu Asn Trp Glu Ile Thr Leu Asp Ser Gly Ser Phe
        115                 120                 125

Gln Ala Leu Gly Leu Val Gly Leu Gln Glu Ser Val Arg Tyr Ile Ala
    130                 135                 140

Val Leu Lys Lys Thr Thr Leu Ala Leu His His Leu Ser Ser Gly His
145                 150                 155                 160

Leu Lys Trp Val Glu His Leu Pro Glu Ser Asp Ser Ile His Tyr Gln
                165                 170                 175

Met Val Tyr Ser Tyr Gly Ser Gly Val Val Trp Ala Leu Gly Val Val
            180                 185                 190

Pro Phe Ser His Val Asn Ile Val Lys Phe Asn Val Glu Asp Gly Glu
        195                 200                 205

Ile Val Gln Gln Val Arg Val Ser Thr Pro Trp Leu Gln His Leu Ser
    210                 215                 220

Gly Ala Cys Gly Val Val Asp Glu Ala Val Leu Val Cys Pro Asp Pro
225                 230                 235                 240

Ser Ser Arg Ser Leu Gln Thr Leu Ala Leu Glu Thr Glu Trp Glu Leu
                245                 250                 255

Arg Gln Ile Pro Leu Gln Ser Leu Asp Leu Glu Phe Gly Ser Gly Phe
            260                 265                 270

Gln Pro Arg Val Leu Pro Thr Gln Pro Asn Pro Val Asp Ala Ser Gly
        275                 280                 285

Pro Ser Ser Ser Cys Thr Cys Pro Gln Ala Thr Met Leu Cys Cys Ser
    290                 295                 300

Thr Ile Met Glu Arg 
305



<210> 2596
<211> 149
<212> PRT
<213> Homo sapiens

<400> 2596
Met Asn Arg Phe Ala Leu Met Lys Cys Arg Pro Tyr Leu Tyr Ile Arg
  1               5                  10                  15

Leu Phe Leu Pro Ser Val Cys His Phe Pro Thr Cys Leu Pro Tyr Pro
             20                  25                  30

Pro Pro Thr His His Leu Gly Leu Pro Leu Gly Val Arg Gly Ser Ser
         35                  40                  45

His His Met Lys Thr Ser Gly Trp Val Leu Pro His Cys Pro Ser Pro
     50                  55                  60

Cys Ser Cys Pro Lys Pro Ser Ile Arg Leu Trp Ser Ser Thr Gln Ser
 65                  70                  75                  80

Asp Glu Asn Thr Val Asn Ala Leu Ile Gly Gly Phe Leu Val Leu Leu
                 85                  90                  95

His Ile Met Cys Asn Val Val Ala Leu Thr Phe Tyr Ala Thr Ile Tyr
            100                 105                 110

Glu Asp Leu Cys Cys Thr Cys Asn Lys Tyr Ile Glu Lys Ala His Thr
        115                 120                 125

Ser Tyr Gly Glu Leu Tyr Gly Phe Val Cys Val Leu Gly Leu Ala Gly
    130                 135                 140

Gly Trp Val Gly Ser 
145



<210> 2597
<211> 359
<212> PRT
<213> Homo sapiens

<400> 2597
Met Pro Leu Glu Leu Glu Leu Cys Pro Gly Arg Trp Val Gly Gly Gln
  1               5                  10                  15

His Pro Cys Phe Ile Ile Ala Glu Ile Gly Gln Asn His Gln Gly Asp
             20                  25                  30

Leu Asp Val Ala Lys Arg Met Ile Arg Met Ala Lys Glu Cys Gly Ala
         35                  40                  45

Asp Cys Ala Lys Phe Gln Lys Ser Glu Leu Glu Phe Lys Phe Asn Arg
     50                  55                  60

Lys Ala Leu Glu Arg Pro Tyr Thr Ser Lys His Ser Trp Gly Lys Thr
 65                  70                  75                  80

Tyr Gly Glu His Lys Arg His Leu Glu Phe Ser His Asp Gln Tyr Arg
                 85                  90                  95

Glu Leu Gln Arg Tyr Ala Glu Glu Val Gly Ile Phe Phe Thr Ala Ser
            100                 105                 110

Gly Met Asp Glu Met Ala Val Glu Phe Leu His Glu Leu Asn Val Pro
        115                 120                 125

Phe Phe Lys Val Gly Ser Gly Asp Thr Asn Asn Phe Pro Tyr Leu Glu
    130                 135                 140

Lys Thr Ala Lys Lys Gly Arg Pro Met Val Ile Ser Ser Gly Met Gln
145                 150                 155                 160

Ser Met Asp Thr Met Lys Gln Val Tyr Gln Ile Val Lys Pro Leu Asn
                165                 170                 175

Pro Asn Phe Cys Phe Leu Gln Cys Thr Ser Ala Tyr Pro Leu Gln Pro
            180                 185                 190

Glu Asp Val Asn Leu Arg Val Ile Ser Glu Tyr Gln Lys Leu Phe Pro
        195                 200                 205

Asp Ile Pro Ile Gly Tyr Ser Gly His Glu Thr Gly Ile Ala Ile Ser
    210                 215                 220

Val Ala Ala Val Ala Leu Gly Ala Lys Val Leu Glu Arg His Ile Thr
225                 230                 235                 240

Leu Asp Lys Thr Trp Lys Gly Ser Asp His Ser Ala Ser Leu Glu Pro
                245                 250                 255

Gly Glu Leu Ala Glu Leu Val Arg Ser Val Arg Leu Val Glu Arg Ala
            260                 265                 270

Leu Gly Ser Pro Thr Lys Gln Leu Leu Pro Cys Glu Met Ala Cys Asn
        275                 280                 285

Glu Lys Leu Gly Lys Ser Val Val Ala Lys Val Lys Ile Pro Glu Gly
    290                 295                 300

Thr Ile Leu Thr Met Asp Met Leu Thr Val Lys Val Gly Glu Pro Lys
305                 310                 315                 320

Gly Tyr Pro Pro Glu Asp Ile Phe Asn Leu Val Gly Lys Lys Val Leu
                325                 330                 335

Val Thr Val Glu Glu Asp Asp Thr Ile Met Glu Glu Leu Val Asp Asn
            340                 345                 350

His Gly Lys Lys Ile Lys Ser 
        355



<210> 2598
<211> 198
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2598
Met Phe Arg Cys Pro Ser Asn His Gln Met Val Gly Ser Gly Leu Leu
  1               5                  10                  15

Thr Cys Thr Trp Lys Gly Ser Ile Ala Glu Trp Ser Ser Gly Ser Pro
             20                  25                  30

Val Cys Lys Leu Val Pro Pro His Glu Thr Phe Gly Phe Lys Val Ala
         35                  40                  45

Val Ile Ala Ser Ile Val Ser Cys Ala Ile Ile Leu Leu Met Ser Met
     50                  55                  60

Ala Phe Leu Thr Cys Cys Leu Leu Lys Cys Val Lys Lys Ser Xaa Arg
 65                  70                  75                  80

Arg Arg Ser Asn Arg Ser Ala Gln Leu Trp Ser Gln Leu Lys Asp Glu
                 85                  90                  95

Asp Leu Glu Thr Val Gln Ala Ala Tyr Leu Gly Leu Lys His Phe Asn
            100                 105                 110

Lys Pro Val Ser Gly Pro Ser Gln Ala His Asp Asn His Ser Phe Thr
        115                 120                 125

Thr Asp His Gly Glu Ser Thr Ser Lys Leu Ala Ser Xaa Thr Arg Ser
    130                 135                 140

Val Asp Lys Asp Pro Gly Ile Pro Arg Ala Leu Ser Leu Xaa Gly Ser
145                 150                 155                 160

Ser Ser Ser Pro Gln Ala Gln Val Met Val His Met Ala Asn Pro Arg
                165                 170                 175

Gln Pro Leu Leu Ala Ser Gly Leu Ala Thr Gly Asn Ala Thr Thr Ala
            180                 185                 190

Arg Ser Xaa Cys Leu Gly 
        195



<210> 2599
<211> 121
<212> PRT
<213> Homo sapiens

<400> 2599
Met Val His Ile Gln Asn Ala Ala Leu Ala Gly Gly Val Val Val Gly
  1               5                  10                  15

Thr Ser Ser Glu Met Met Leu Thr Pro Phe Gly Ala Leu Ala Ala Gly
             20                  25                  30

Phe Leu Ala Gly Thr Val Ser Thr Leu Gly Tyr Lys Phe Phe Thr Pro
         35                  40                  45

Ile Leu Glu Ser Lys Phe Lys Val Gln Asp Thr Cys Gly Val His Asn
     50                  55                  60

Leu His Gly Met Pro Gly Val Leu Gly Ala Leu Leu Gly Val Leu Val
 65                  70                  75                  80

Ala Gly Leu Ala Thr His Glu Ala Tyr Gly Asp Gly Leu Glu Ser Val
                 85                  90                  95

Phe Pro Leu Ile Ala Glu Gly Gln Arg Met Pro Arg His Arg Pro Cys
            100                 105                 110

Thr Ser Ser Ser Gly Cys Leu Ser His 
        115                 120



<210> 2600
<211> 195
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (167)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2600
Met Glu Ser Thr Leu Gly Ala Gly Ile Val Ile Ala Glu Ala Leu Gln
  1               5                  10                  15

Asn Gln Leu Ala Trp Leu Glu Asn Val Trp Leu Trp Ile Thr Phe Leu
             20                  25                  30

Gly Asp Pro Lys Ile Leu Phe Leu Phe Tyr Phe Pro Ala Ala Tyr Tyr
         35                  40                  45

Ala Ser Arg Arg Val Gly Ile Ala Val Leu Trp Ile Ser Leu Ile Thr
     50                  55                  60

Glu Trp Leu Asn Leu Ile Phe Lys Trp Phe Leu Phe Gly Asp Arg Pro
 65                  70                  75                  80

Phe Trp Trp Val His Glu Ser Gly Tyr Tyr Ser Gln Ala Pro Ala Gln
                 85                  90                  95

Val His Gln Phe Pro Ser Ser Cys Glu Thr Gly Pro Gly Ser Pro Ser
            100                 105                 110

Gly His Cys Met Ile Thr Gly Ala Ala Leu Trp Pro Ile Met Thr Ala
        115                 120                 125

Leu Ser Ser Gln Val Ala Thr Arg Ala Arg Ser Arg Trp Val Arg Val
    130                 135                 140

Met Pro Ser Leu Ala Tyr Cys Thr Phe Leu Leu Ala Val Gly Leu Ser
145                 150                 155                 160

Arg Ile Phe Ile Leu Ala Xaa Phe Pro Xaa Gln Val Leu Ala Gly Leu
                165                 170                 175

Ile Thr Gly Ala Val Leu Gly Trp Leu Met Thr Pro Arg Val Pro Met
            180                 185                 190

Glu Arg Asp 
        195



<210> 2601
<211> 182
<212> PRT
<213> Homo sapiens

<400> 2601
Met Trp Pro Pro Asp Pro Asp Pro Asp Pro Asp Pro Glu Pro Ala Gly
  1               5                  10                  15

Gly Ser Arg Pro Gly Pro Ala Val Pro Gly Leu Arg Ala Leu Leu Pro
             20                  25                  30

Ala Arg Ala Phe Leu Cys Ser Leu Lys Gly Arg Leu Leu Leu Ala Glu
         35                  40                  45

Ser Gly Leu Ser Phe Ile Thr Phe Ile Cys Tyr Val Ala Ser Ser Ala
     50                  55                  60

Ser Ala Phe Leu Thr Ala Pro Leu Leu Glu Phe Leu Leu Ala Leu Tyr
 65                  70                  75                  80

Phe Leu Phe Ala Asp Ala Met Gln Leu Asn Asp Lys Trp Gln Gly Leu
                 85                  90                  95

Cys Trp Pro Met Met Asp Phe Leu Arg Cys Val Thr Ala Ala Leu Ile
            100                 105                 110

Tyr Phe Ala Ile Ser Ile Thr Ala Ile Ala Lys Tyr Ser Asp Gly Ala
        115                 120                 125

Ser Lys Ala Ala Gly Val Phe Gly Phe Phe Ala Thr Ile Val Phe Ala
    130                 135                 140

Thr Asp Phe Tyr Leu Ile Phe Asn Asp Val Ala Lys Phe Leu Lys Gln
145                 150                 155                 160

Gly Asp Ser Ala Asp Glu Thr Thr Ala His Lys Thr Glu Glu Glu Asn
                165                 170                 175

Ser Asp Ser Asp Ser Asp 
            180



<210> 2602
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2602
Met Ala Thr Ala Glu Gly Leu Ile Lys Arg Ser Lys Gly Lys Glu Arg
  1               5                  10                  15

Pro Phe Val Leu Thr Arg Ser Phe Phe Ala Gly Ser Gln Lys Tyr Gly
             20                  25                  30

Ala Val Trp Thr Gly Asp Asn Thr Ala Glu Trp Ser Asn Leu Lys Ile
         35                  40                  45

Ser Ile Pro Met Leu Leu Thr Leu Ser Ile Thr Gly Ile Ser Phe Cys
     50                  55                  60

Gly Leu Tyr Ile Gly Gly Phe Ile Gly Glu Ser Arg Asp Arg Ala Ala
 65                  70                  75                  80

Ser Ala Leu Val Pro Gly Trp Ser Xaa Pro Ala Leu Leu Pro Trp Pro
                 85                  90                  95

Cys Xaa Met Glu His Gln Ala Thr Arg Ala Xaa Leu Phe Gly Glu Glu
            100                 105                 110

His Thr Arg 
        115



<210> 2603
<211> 257
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2603
Met Leu Gly Ser Leu Val Ser Ser Tyr Pro Val Thr Gly Ser Phe Gly
  1               5                  10                  15

Arg Thr Ala Val Asn Ala Gln Ser Gly Val Cys Thr Pro Ala Gly Ala
             20                  25                  30

Leu Val Thr Gly Val Leu Val Leu Leu Ser Leu Asp Tyr Leu Thr Ser
         35                  40                  45

Leu Phe Tyr Tyr Ile Pro Lys Ser Ala Leu Ala Ala Val Ile Ile Met
     50                  55                  60

Ala Val Ala Pro Leu Phe Asp Thr Lys Ile Phe Arg Thr Leu Trp Arg
 65                  70                  75                  80

Val Lys Arg Leu Asp Leu Leu Pro Leu Cys Val Thr Phe Leu Leu Cys
                 85                  90                  95

Phe Trp Glu Val Xaa Tyr Gly Xaa Leu Ala Gly Gly Leu Val Ser Leu
            100                 105                 110

Leu Met Leu Leu His Ser Ala Ala Arg Pro Xaa Thr Lys Val Ser Glu
        115                 120                 125

Gly Pro Val Leu Val Leu Gln Pro Ala Ser Gly Leu Ser Phe Pro Ala
    130                 135                 140

Met Glu Ala Leu Arg Glu Glu Ile Leu Ser Arg Ala Leu Glu Val Ser
145                 150                 155                 160

Pro Pro Arg Cys Leu Val Leu Glu Cys Thr His Val Cys Ser Ile Asp
                165                 170                 175

Tyr Thr Val Val Leu Gly Leu Gly Glu Leu Leu Gln Asp Phe Gln Lys
            180                 185                 190

Gln Gly Val Ala Leu Ala Phe Val Gly Leu Gln Val Pro Val Leu Arg
        195                 200                 205

Val Leu Leu Ser Ala Asp Leu Lys Gly Phe Gln Tyr Phe Ser Thr Leu
    210                 215                 220

Glu Glu Ala Glu Lys His Leu Arg Gln Glu Pro Gly Thr Gln Pro Tyr
225                 230                 235                 240

Asn Ile Arg Glu Asp Ser Ile Leu Asp Gln Lys Val Ala Leu Leu Lys
                245                 250                 255

Ala 




<210> 2604
<211> 178
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (105)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (114)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (154)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (156)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2604
Met Pro Ser Asn Gln Gly Lys Ile Asp Asn Glu Glu Gln Pro Pro His
  1               5                  10                  15

Glu Gly Lys Pro Glu Val Ala Cys Ile Leu Glu Asp Lys Lys Leu Glu
             20                  25                  30

Asn Glu Gly Asn Thr Glu Asn Thr Gly Lys Arg Val Glu Glu Pro Leu
         35                  40                  45

Lys Asp Lys Glu Lys Pro Glu Ser Ala Gly Lys Ala Lys Gly Glu Gly
     50                  55                  60

Lys Ser Glu Arg Lys Gly Lys Ser Glu Met Gln Gly Gly Ser Lys Thr
 65                  70                  75                  80

Glu Gly Lys Pro Glu Arg Gly Gly Arg Ala Glu Gly Glu Gly Glu Pro
                 85                  90                  95

Asp Xaa Glu Arg Glu Pro Glu Xaa Xaa Gly Glu Pro Glu Xaa Glu Thr
            100                 105                 110

Arg Xaa Ser Gly Lys Arg Pro Xaa Glu Val Val Leu Pro Arg Lys Ala
        115                 120                 125

Gln Lys Lys Asn Gln Gln Gly Phe Val His Tyr Leu Ser Ile Phe Arg
    130                 135                 140

Ser Leu Thr Val Leu Ile Phe Ser Ile Xaa Gly Xaa Leu Gly Val Phe
145                 150                 155                 160

Ala Leu Val Arg Leu Gly Leu Lys Glu Lys Ala Thr Asp Phe Gly Leu
                165                 170                 175

Phe Leu 




<210> 2605
<211> 245
<212> PRT
<213> Homo sapiens

<400> 2605
Met Lys Val Pro Gln Ser Gly Thr Leu Lys Leu Ser His Leu Gln Glu
  1               5                  10                  15

Gly Thr Tyr Thr Phe Gln Leu Thr Val Thr Asp Thr Ala Gly Gln Arg
             20                  25                  30

Ser Ser Asp Asn Val Ser Val Thr Val Leu Arg Ala Ala Tyr Ser Thr
         35                  40                  45

Gly Gly Cys Leu His Thr Cys Ser Arg Tyr His Phe Phe Cys Asp Asp
     50                  55                  60

Gly Cys Cys Ile Asp Ile Thr Leu Ala Cys Asp Gly Val Gln Gln Cys
 65                  70                  75                  80

Pro Asp Gly Ser Asp Glu Asp Phe Cys Gln Asn Leu Gly Leu Asp Arg
                 85                  90                  95

Lys Met Val Thr His Thr Ala Ala Ser Pro Ala Leu Pro Arg Thr Thr
            100                 105                 110

Gly Pro Ser Glu Asp Ala Gly Gly Asp Ser Leu Val Glu Lys Ser Gln
        115                 120                 125

Lys Ala Thr Ala Pro Asn Lys Pro Pro Ala Leu Ser Asn Thr Glu Lys
    130                 135                 140

Arg Asn His Ser Ala Phe Trp Gly Pro Glu Ser Gln Ile Ile Pro Val
145                 150                 155                 160

Met Pro Asp Ser Ser Ser Ser Gly Lys Asn Arg Lys Glu Glu Ser Tyr
                165                 170                 175

Ile Phe Glu Ser Lys Gly Asp Gly Gly Gly Gly Glu His Pro Ala Pro
            180                 185                 190

Glu Thr Gly Ala Val Leu Pro Leu Ala Leu Gly Leu Ala Ile Thr Ala
        195                 200                 205

Leu Leu Leu Leu Met Val Ala Cys Arg Leu Arg Leu Val Lys Gln Lys
    210                 215                 220

Leu Lys Lys Ala Arg Pro Ile Thr Ser Glu Glu Ser Asp Tyr Leu Ile
225                 230                 235                 240

Asn Gly Met Tyr Leu 
                245



<210> 2606
<211> 558
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (39)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2606
Met Ser Asp Leu Arg Arg Lys Arg Thr Ala His Glu Arg Ala Lys Glu
  1               5                  10                  15

Leu Tyr Ser Ser Gly Glu Phe Ser Ser Gly Arg Lys Trp Gly Asp Asp
             20                  25                  30

Ala Pro Lys Glu Glu Val Xaa Thr Gly Ala Val Asn Leu Ile Glu Ser
         35                  40                  45

Gly Ala Cys Gly Ala Phe Val His Gly Leu Glu Asp Glu Met Tyr Glu
     50                  55                  60

Val Arg Ile Ala Ala Val Glu Ala Leu Cys Met Leu Ala Gln Ser Ser
 65                  70                  75                  80

Pro Ser Phe Ala Glu Lys Cys Leu Asp Phe Leu Val Asp Met Phe Asn
                 85                  90                  95

Asp Glu Ile Glu Glu Val Arg Leu Gln Ser Ile His Thr Met Arg Lys
            100                 105                 110

Ile Ser Asn Asn Ile Thr Leu Arg Glu Asp Gln Leu Asp Thr Val Leu
        115                 120                 125

Ala Val Leu Glu Asp Ser Ser Arg Asp Ile Arg Glu Ala Leu His Glu
    130                 135                 140

Leu Leu Cys Cys Thr Asn Val Ser Thr Lys Glu Gly Ile His Leu Ala
145                 150                 155                 160

Leu Val Glu Leu Leu Lys Asn Leu Thr Lys Tyr Pro Thr Asp Arg Asp
                165                 170                 175

Ser Ile Trp Lys Cys Leu Lys Phe Leu Gly Ser Arg His Pro Thr Leu
            180                 185                 190

Val Leu Pro Leu Val Pro Glu Leu Leu Ser Thr His Pro Phe Phe Asp
        195                 200                 205

Thr Ala Glu Pro Asp Met Asp Asp Pro Ala Tyr Ile Ala Val Leu Val
    210                 215                 220

Leu Ile Phe Asn Ala Ala Lys Thr Cys Pro Thr Met Pro Ala Leu Phe
225                 230                 235                 240

Ser Asp His Thr Phe Arg His Tyr Ala Tyr Leu Arg Asp Ser Leu Ser
                245                 250                 255

His Leu Val Pro Ala Leu Arg Leu Pro Gly Arg Lys Leu Val Ser Ser
            260                 265                 270

Ala Val Ser Pro Ser Ile Ile Pro Gln Glu Asp Pro Ser Gln Gln Phe
        275                 280                 285

Leu Gln Gln Ser Leu Glu Arg Val Tyr Ser Leu Gln His Leu Asp Pro
    290                 295                 300

Gln Gly Ala Gln Glu Leu Leu Glu Phe Thr Ile Arg Asp Leu Gln Arg
305                 310                 315                 320

Leu Gly Glu Leu Gln Ser Glu Leu Ala Gly Val Ala Asp Phe Ser Ala
                325                 330                 335

Thr Tyr Leu Arg Cys Gln Leu Leu Leu Ile Lys Ala Leu Gln Glu Lys
            340                 345                 350

Leu Trp Asn Val Ala Ala Pro Leu Tyr Leu Lys Gln Ser Asp Leu Ala
        355                 360                 365

Ser Ala Ala Ala Lys Gln Ile Met Glu Glu Thr Tyr Lys Met Glu Phe
    370                 375                 380

Met Tyr Ser Gly Val Glu Asn Lys Gln Val Val Ile Ile His His Met
385                 390                 395                 400

Arg Leu Gln Ala Lys Ala Leu Gln Leu Ile Val Thr Ala Arg Thr Thr
                405                 410                 415

Arg Gly Leu Asp Pro Leu Phe Gly Met Cys Glu Lys Phe Leu Gln Glu
            420                 425                 430

Val Asp Phe Phe Gln Arg Tyr Phe Ile Ala Asp Leu Pro His Leu Gln
        435                 440                 445

Asp Ser Phe Val Asp Lys Leu Leu Asp Leu Met Pro Arg Leu Met Thr
    450                 455                 460

Ser Lys Pro Ala Glu Val Val Lys Ile Leu Gln Thr Met Leu Arg Gln
465                 470                 475                 480

Ser Ala Phe Leu His Leu Pro Leu Pro Glu Gln Ile His Lys Ala Ser
                485                 490                 495

Ala Thr Ile Ile Glu Pro Ala Gly Glu Ser Asp Asn Pro Leu Arg Phe
            500                 505                 510

Thr Ser Gly Leu Val Val Ala Leu Asp Val Asp Ala Thr Pro Val Leu
        515                 520                 525

Ala Phe Gln Asn Ala Pro Gly Trp Arg Val Val Arg Cys His His Arg
    530                 535                 540

Trp Lys Pro Ala Ser Arg Ala Pro Phe Pro Ser Ala Ser Leu 
545                 550                 555



<210> 2607
<211> 175
<212> PRT
<213> Homo sapiens

<400> 2607
Met Ser His Gly Ala Gly Leu Val Arg Thr Thr Cys Ser Ser Gly Ser
  1               5                  10                  15

Ala Leu Gly Pro Gly Ala Gly Ala Ala Gln Pro Ser Ala Ser Pro Leu
             20                  25                  30

Glu Gly Leu Leu Asp Leu Ser Tyr Pro Arg Thr His Ala Ala Leu Leu
         35                  40                  45

Lys Val Ala Gln Met Val Thr Leu Leu Ile Ala Phe Ile Cys Val Arg
     50                  55                  60

Ser Ser Leu Trp Thr Asn Tyr Ser Ala Tyr Ser Tyr Phe Glu Val Val
 65                  70                  75                  80

Thr Ile Cys Asp Leu Ile Met Ile Leu Ala Phe Tyr Leu Val His Leu
                 85                  90                  95

Phe Arg Phe Tyr Arg Val Leu Thr Cys Ile Ser Trp Pro Leu Ser Glu
            100                 105                 110

Leu Leu His Tyr Leu Ile Gly Thr Leu Leu Leu Leu Ile Ala Ser Ile
        115                 120                 125

Val Ala Ala Ser Lys Ser Tyr Asn Gln Ser Gly Leu Val Ala Gly Ala
    130                 135                 140

Ile Phe Gly Phe Met Ala Thr Phe Leu Cys Met Ala Ser Ile Trp Leu
145                 150                 155                 160

Ser Tyr Lys Ile Ser Cys Val Thr Gln Ser Thr Asp Ala Ala Val 
                165                 170                 175



<210> 2608
<211> 284
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (26)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (45)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (60)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (213)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (224)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (225)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (237)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (247)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (283)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2608
Met Met Leu Leu Ser Glu Gly Met Lys Glu Glu Gly Leu Phe Arg Leu
  1               5                  10                  15

Ala Ala Gly Ala Ser Val Leu Lys Arg Xaa Lys Gln Thr Met Ala Ser
             20                  25                  30

Asp Pro Xaa Ser Leu Glu Glu Phe Cys Ser Xaa Pro Xaa Ala Val Ala
         35                  40                  45

Gly Ala Leu Lys Ser Tyr Leu Arg Glu Leu Pro Xaa Pro Leu Met Thr
     50                  55                  60

Phe Asp Leu Tyr Asp Asp Trp Met Arg Ala Ala Ser Leu Lys Glu Pro
 65                  70                  75                  80

Gly Ala Arg Leu Gln Ala Leu Gln Glu Val Cys Ser Arg Leu Pro Pro
                 85                  90                  95

Glu Asn Leu Ser Asn Leu Arg Tyr Leu Met Lys Phe Leu Ala Arg Leu
            100                 105                 110

Ala Glu Glu Gln Glu Val Asn Lys Met Thr Pro Ser Asn Ile Ala Ile
        115                 120                 125

Val Leu Gly Pro Asn Leu Leu Trp Pro Pro Glu Lys Glu Gly Asp Gln
    130                 135                 140

Ala Gln Leu Asp Ala Ala Ser Val Ser Ser Ile Gln Val Val Gly Val
145                 150                 155                 160

Val Glu Ala Leu Ile Gln Ser Ala Asp Thr Leu Phe Pro Gly Asp Ile
                165                 170                 175

Asn Phe Asn Val Ser Gly Leu Phe Ser Ala Val Thr Leu Gln Asp Thr
            180                 185                 190

Val Ser Asp Arg Leu Ala Ser Glu Glu Leu Pro Ser Thr Ala Val Pro
        195                 200                 205

Thr Pro Ala Thr Xaa Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Xaa
    210                 215                 220

Xaa Pro Ala Leu Ala Ser Ala Ala Thr Lys Glu Arg Xaa Glu Ser Glu
225                 230                 235                 240

Val Pro Pro Arg Pro Ala Xaa Pro Lys Val Thr Arg Ser Pro Pro Glu
                245                 250                 255

Thr Ala Ala Pro Val Glu Asp Met Ala Arg Arg Thr Lys Arg Pro Ala
            260                 265                 270

Pro Ala Gly Pro Pro Cys Arg Pro Pro Gly Xaa Arg 
        275                 280



<210> 2609
<211> 199
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2609
Met Asp Glu Ala Gly Asn Lys Val Glu Gln Cys Lys Xaa Gln Leu Ala
  1               5                  10                  15

Ala Asp Met Tyr Asn Phe Met Ala Lys Glu Gly Glu Tyr Gly Lys Phe
             20                  25                  30

Phe Val Thr Leu Leu Glu Ala Gln Ala Asp Tyr His Arg Lys Ala Leu
         35                  40                  45

Ala Val Leu Glu Lys Thr Leu Pro Glu Met Arg Ala His Gln Asp Lys
     50                  55                  60

Trp Ala Glu Lys Pro Ala Phe Gly Thr Pro Leu Glu Glu His Leu Lys
 65                  70                  75                  80

Arg Ser Gly Arg Glu Ile Ala Leu Pro Ile Glu Ala Cys Val Met Leu
                 85                  90                  95

Leu Leu Glu Thr Gly Met Lys Glu Glu Gly Leu Phe Arg Ile Gly Ala
            100                 105                 110

Gly Ala Ser Lys Leu Lys Lys Leu Lys Ala Ala Leu Asp Cys Ser Thr
        115                 120                 125

Ser His Leu Asp Glu Phe Tyr Ser Asp Pro His Ala Val Ala Gly Ala
    130                 135                 140

Leu Lys Ser Tyr Leu Arg Glu Leu Pro Glu Pro Leu Met Thr Phe Asn
145                 150                 155                 160

Leu Tyr Glu Glu Trp Thr Gln Val Ala Ser Val Gln Asp Gln Asp Lys
                165                 170                 175

Lys Leu Gln Asp Leu Trp Arg Thr Cys Gln Lys Leu Pro Pro Gln Asn
            180                 185                 190

Xaa Val Asn Phe Arg Tyr Val 
        195



<210> 2610
<211> 324
<212> PRT
<213> Homo sapiens

<400> 2610
Met Arg Ile Pro Leu Ile Phe Gln Lys Leu Ile Ser Arg Ile Glu Glu
  1               5                  10                  15

Arg Gly Leu Glu Thr Glu Gly Leu Leu Arg Ile Pro Gly Ala Ala Ile
             20                  25                  30

Arg Ile Lys Asn Leu Cys Gln Glu Leu Glu Ala Lys Phe Tyr Glu Gly
         35                  40                  45

Thr Phe Asn Trp Glu Ser Val Lys Gln His Asp Ala Ala Ser Leu Leu
     50                  55                  60

Lys Leu Phe Ile Arg Glu Leu Pro Gln Pro Leu Leu Ser Val Glu Tyr
 65                  70                  75                  80

Leu Lys Ala Phe Gln Ala Val Gln Asn Leu Pro Thr Lys Lys Gln Gln
                 85                  90                  95

Leu Gln Ala Leu Asn Leu Leu Val Ile Leu Leu Pro Asp Ala Asn Arg
            100                 105                 110

Asp Thr Leu Lys Ala Leu Leu Glu Phe Leu Gln Arg Val Ile Asp Asn
        115                 120                 125

Lys Glu Lys Asn Lys Met Thr Val Met Asn Val Ala Met Val Met Ala
    130                 135                 140

Pro Asn Leu Phe Met Cys His Ala Leu Gly Leu Lys Ser Ser Glu Gln
145                 150                 155                 160

Arg Glu Phe Val Met Ala Ala Gly Thr Ala Asn Thr Met His Leu Leu
                165                 170                 175

Ile Lys Tyr Gln Lys Leu Leu Trp Thr Ile Pro Lys Phe Ile Val Asn
            180                 185                 190

Gln Val Arg Lys Gln Asn Thr Glu Asn His Lys Lys Asp Lys Arg Ala
        195                 200                 205

Met Lys Lys Leu Leu Lys Lys Met Ala Tyr Asp Arg Glu Lys Tyr Glu
    210                 215                 220

Lys Gln Asp Lys Ser Thr Asn Asp Ala Asp Val Pro Gln Gly Val Ile
225                 230                 235                 240

Arg Val Gln Ala Pro His Leu Ser Lys Val Ser Met Ala Ile Gln Leu
                245                 250                 255

Thr Glu Glu Leu Lys Ala Ser Asp Val Leu Ala Arg Phe Leu Ser Gln
            260                 265                 270

Glu Ser Gly Val Ala Gln Thr Leu Lys Lys Gly Glu Val Phe Leu Tyr
        275                 280                 285

Glu Ile Gly Gly Asn Ile Gly Glu Arg Cys Leu Asp Asp Asp Thr Tyr
    290                 295                 300

Met Lys Asp Leu Tyr Gln Leu Asn Pro Asn Ala Glu Trp Val Ile Lys
305                 310                 315                 320

Ser Lys Pro Leu 




<210> 2611
<211> 241
<212> PRT
<213> Homo sapiens

<400> 2611
Met Trp Asp Gln Arg Leu Val Arg Leu Ala Leu Leu Gln His Leu Arg
  1               5                  10                  15

Ala Phe Tyr Gly Ile Lys Val Lys Gly Val Arg Gly Gln Cys Asp Arg
             20                  25                  30

Arg Arg His Glu Thr Ala Ala Thr Glu Ile Gly Gly Lys Ile Phe Gly
         35                  40                  45

Val Pro Phe Asn Ala Leu Pro His Ser Ala Val Pro Glu Tyr Gly His
     50                  55                  60

Ile Pro Ser Phe Leu Val Asp Ala Cys Thr Ser Leu Glu Asp His Ile
 65                  70                  75                  80

His Thr Glu Gly Leu Phe Arg Lys Ser Gly Ser Val Ile Arg Leu Lys
                 85                  90                  95

Ala Leu Lys Asn Lys Val Asp His Gly Glu Gly Cys Leu Ser Ser Ala
            100                 105                 110

Pro Pro Cys Asp Ile Ala Gly Leu Leu Lys Gln Phe Phe Arg Glu Leu
        115                 120                 125

Pro Glu Pro Ile Leu Pro Ala Asp Leu His Glu Ala Leu Leu Lys Ala
    130                 135                 140

Gln Gln Leu Gly Thr Glu Glu Lys Asn Lys Ala Ile Leu Leu Leu Ser
145                 150                 155                 160

Cys Leu Leu Ala Asp His Thr Val His Val Leu Arg Tyr Phe Phe Asn
                165                 170                 175

Phe Leu Arg Asn Val Ser Leu Arg Ser Ser Glu Asn Lys Met Asp Ser
            180                 185                 190

Ser Asn Leu Ala Val Ile Phe Ala Pro Asn Leu Leu Gln Thr Ser Glu
        195                 200                 205

Gly His Glu Lys Met Ser Ser Asn Ala Glu Lys Lys Val Arg Leu Gln
    210                 215                 220

Ala Ala Val Val Gln Thr Leu Ile Asp Tyr Ala Ser Asp Ile Gly Lys
225                 230                 235                 240

Met 




<210> 2612
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2612
Met Gly Thr Trp Gly Gly Asp Gly Asn Lys Arg Gly Thr Gly Lys Cys
  1               5                  10                  15

Pro Asn Thr Pro Val Val Pro Ile Pro Cys Arg Leu Pro Ala Phe Pro
             20                  25                  30

Lys Pro Ser Pro Thr Tyr Leu Arg Thr Ser Ala Glu Gln Thr Leu Pro
         35                  40                  45

Leu Leu Leu Pro His Leu His Gly Leu Cys Phe Ile Asn Leu Cys Ile
     50                  55                  60

Leu Ala Ser Gln His Ala Trp Xaa Gln Leu Thr Phe Trp Glu Ala Ser
 65                  70                  75                  80

Gln Xaa Tyr Leu Leu Phe Leu Ser Leu Thr Leu Ala Thr Val Lys Pro
                 85                  90                  95

Leu Val Glu Pro Gly Pro Xaa Leu His Val Gly 
            100                 105



<210> 2613
<211> 131
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2613
Met Glu Glu Gly Gly Asn Leu Gly Gly Leu Ile Lys Met Val His Leu
  1               5                  10                  15

Leu Val Leu Ser Gly Ala Trp Gly Met Gln Met Trp Val Thr Phe Val
             20                  25                  30

Ser Gly Phe Leu Leu Phe Arg Ser Leu Pro Arg His Thr Phe Gly Leu
         35                  40                  45

Val Gln Ser Lys Leu Phe Pro Phe Tyr Phe His Ile Ser Met Gly Cys
     50                  55                  60

Ala Phe Ile Asn Leu Cys Ile Leu Ala Ser Gln His Ala Trp Ala Gln
 65                  70                  75                  80

Leu Thr Phe Trp Glu Ala Ser Gln Leu Tyr Leu Leu Phe Leu Ser Leu
                 85                  90                  95

Thr Leu Ala Thr Xaa Asn Xaa Arg Trp Leu Glu Pro Arg Xaa Thr Ala
            100                 105                 110

Ala Met Trp Ala Leu Gln Thr Val Glu Lys Glu Arg Gly Leu Gly Gly
        115                 120                 125

Glu Val Pro 
    130



<210> 2614
<211> 172
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2614
Met Asp Leu Thr Ala Asn Leu Asn Leu Leu Trp Ser Ala Pro Phe Gln
  1               5                  10                  15

Ile Leu Met Ala Val Tyr Leu Leu Trp Gln Glu Leu Gly Pro Ala Val
             20                  25                  30

Leu Ala Gly Val Ala Val Leu Val Phe Val Ile Pro Ile Asn Ala Leu
         35                  40                  45

Ala Ala Thr Lys Ile Lys Lys Leu Lys Val Ser Leu Ala Thr Leu Cys
     50                  55                  60

Val Tyr Phe Leu Leu Asp Glu Gly Asn Ile Leu Thr Ala Thr Lys Val
 65                  70                  75                  80

Phe Thr Ser Met Ser Leu Phe Asn Ile Leu Arg Ile Pro Leu Phe Glu
                 85                  90                  95

Leu Pro Thr Val Ile Ser Ala Val Val Gln Thr Lys Ile Ser Leu Gly
            100                 105                 110

Arg Leu Glu Asp Phe Leu Asn Thr Glu Glu Leu Leu Pro Gln Ser Ile
        115                 120                 125

Glu Thr Asn Tyr Thr Gly Asp His Ala Ile Gly Phe Thr Asp Ala Ser
    130                 135                 140

Phe Ser Trp Asp Lys Thr Gly Met Pro Val Leu Lys Glu Ala Leu Trp
145                 150                 155                 160

Leu Met Xaa Leu Asn Lys Pro Gly Phe Lys Ile Ala 
                165                 170



<210> 2615
<211> 146
<212> PRT
<213> Homo sapiens

<400> 2615
Met Ser Lys Glu Glu Val Asp Arg Tyr Asn Phe Val Met Leu Ala Leu
  1               5                  10                  15

Ser Ser Ser Phe Leu Val Leu Ser Tyr Leu Leu Thr Arg Trp Cys Gly
             20                  25                  30

Ser Val Gly Phe Ile Leu Ala Asn Cys Phe Asn Met Gly Ile Arg Ile
         35                  40                  45

Thr Gln Ser Leu Cys Phe Ile His Arg Tyr Tyr Arg Arg Ser Pro His
     50                  55                  60

Arg Pro Leu Ala Gly Leu His Leu Ser Pro Val Leu Leu Gly Thr Phe
 65                  70                  75                  80

Ala Leu Ser Gly Gly Val Thr Ala Val Ser Glu Val Phe Leu Cys Cys
                 85                  90                  95

Glu Gln Gly Trp Pro Ala Arg Leu Ala His Ile Ala Val Gly Ala Phe
            100                 105                 110

Cys Leu Gly Ala Thr Leu Gly Thr Ala Phe Leu Thr Glu Thr Lys Leu
        115                 120                 125

Ile His Phe Leu Arg Thr Gln Leu Gly Val Pro Arg Arg Thr Asp Lys
    130                 135                 140

Met Thr 
145



<210> 2616
<211> 140
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (136)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2616
Met Ala Ser Leu Gly Leu Gln Leu Val Gly Tyr Ile Leu Gly Leu Leu
  1               5                  10                  15

Gly Leu Leu Gly Thr Leu Val Ala Met Leu Leu Pro Ser Trp Lys Thr
             20                  25                  30

Ser Ser Tyr Val Gly Ala Ser Ile Val Thr Ala Val Gly Phe Ser Lys
         35                  40                  45

Gly Leu Trp Met Glu Cys Ala Thr His Ser Thr Gly Ile Thr Gln Cys
     50                  55                  60

Asp Ile Tyr Ser Thr Leu Leu Gly Leu Pro Ala Asp Ile Gln Ala Ala
 65                  70                  75                  80

Gln Ala Met Met Val Thr Ser Ser Ala Ile Ser Ser Leu Ala Cys Ile
                 85                  90                  95

Ile Ser Val Val Gly Met Arg Cys Thr Val Phe Cys Gln Glu Ser Arg
            100                 105                 110

Ala Lys Asp Arg Val Ala Val Ala Gly Gly Val Phe Phe Ile Leu Gly
        115                 120                 125

Ser Leu Leu Gly Phe Ile Pro Xaa Ala Trp Asn Leu 
    130                 135                 140



<210> 2617
<211> 115
<212> PRT
<213> Homo sapiens

<400> 2617
Met Ala Val Ala Val Leu Leu Cys Gly Cys Ile Val Ala Thr Val Ser
  1               5                  10                  15

Phe Phe Trp Glu Glu Ser Leu Thr Gln His Val Ala Gly Leu Leu Phe
             20                  25                  30

Leu Met Thr Gly Ile Phe Cys Thr Ile Ser Leu Cys Thr Tyr Ala Ala
         35                  40                  45

Ser Ile Ser Tyr Asp Leu Asn Arg Leu Pro Lys Leu Ile Tyr Ser Leu
     50                  55                  60

Pro Ala Asp Val Glu His Gly Tyr Ser Trp Ser Ile Phe Cys Ala Trp
 65                  70                  75                  80

Cys Ser Leu Gly Phe Ile Val Ala Ala Gly Gly Leu Cys Ile Ala Tyr
                 85                  90                  95

Pro Phe Ile Ser Arg Thr Lys Ile Ala Gln Leu Lys Ser Gly Arg Asp
            100                 105                 110

Ser Thr Val 
        115



<210> 2618
<211> 366
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (116)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2618
Met Pro Gly Ile Leu Trp Met Glu Pro Thr Gln Pro Pro Asp Phe Ala
  1               5                  10                  15

Leu Ala Tyr Arg Pro Ser Phe Pro Glu Asp Arg Glu Pro Gln Ile Pro
             20                  25                  30

Tyr Pro Glu Pro Thr Trp Pro Pro Pro Leu Ser Ala Pro Arg Val Pro
         35                  40                  45

Tyr His Ser Ser Val Leu Ser Val Thr Arg Pro Val Val Val Ser Ala
     50                  55                  60

Thr Xaa Pro Thr Leu Pro Ser Ala His Gln Pro Pro Val Ile Pro Ala
 65                  70                  75                  80

Thr His Pro Ala Leu Ser Arg Asp His Gln Ile Pro Val Ile Ala Ala
                 85                  90                  95

Asn Tyr Pro Asp Leu Pro Ser Ala Tyr Gln Pro Gly Ile Leu Ser Val
            100                 105                 110

Ser His Ser Xaa Gln Pro Pro Ala His Gln Pro Pro Met Ile Ser Thr
        115                 120                 125

Lys Tyr Pro Glu Leu Phe Pro Ala His Gln Ser Pro Met Phe Pro Asp
    130                 135                 140

Thr Arg Val Ala Gly Thr Gln Thr Thr Thr His Leu Pro Gly Ile Pro
145                 150                 155                 160

Pro Asn His Ala Pro Leu Val Thr Thr Leu Gly Ala Gln Leu Pro Pro
                165                 170                 175

Gln Ala Pro Asp Ala Leu Val Leu Arg Thr Gln Ala Thr Gln Leu Pro
            180                 185                 190

Ile Ile Pro Thr Ala Gln Pro Ser Leu Thr Thr Thr Ser Arg Ser Pro
        195                 200                 205

Val Ser Pro Ala His Gln Ile Ser Val Pro Ala Ala Thr Gln Pro Ala
    210                 215                 220

Ala Leu Pro Thr Leu Leu Pro Ser Gln Ser Pro Thr Asn Gln Thr Ser
225                 230                 235                 240

Pro Ile Ser Pro Thr His Pro His Ser Lys Ala Pro Gln Ile Pro Arg
                245                 250                 255

Glu Asp Gly Pro Ser Pro Lys Leu Ala Leu Trp Leu Pro Ser Pro Ala
            260                 265                 270

Pro Thr Ala Ala Pro Thr Ala Leu Gly Glu Ala Gly Leu Ala Glu His
        275                 280                 285

Ser Gln Arg Asp Asp Arg Trp Leu Leu Val Ala Leu Leu Val Pro Thr
    290                 295                 300

Cys Val Phe Leu Val Val Leu Leu Ala Leu Gly Ile Val Tyr Cys Thr
305                 310                 315                 320

Arg Cys Gly Pro His Ala Pro Asn Lys Arg Ile Thr Asp Cys Tyr Arg
                325                 330                 335

Trp Val Ile His Ala Gly Ser Lys Ser Pro Thr Glu Pro Met Pro Pro
            340                 345                 350

Arg Gly Ser Leu Thr Gly Val Gln Thr Cys Arg Thr Ser Val 
        355                 360                 365



<210> 2619
<211> 834
<212> PRT
<213> Homo sapiens

<400> 2619
Met Lys His Thr Leu Ala Leu Leu Ala Pro Leu Leu Gly Leu Gly Leu
  1               5                  10                  15

Gly Leu Ala Leu Ser Gln Leu Ala Ala Gly Ala Thr Asp Cys Lys Phe
             20                  25                  30

Leu Gly Pro Ala Glu His Leu Thr Phe Thr Pro Ala Ala Arg Ala Arg
         35                  40                  45

Trp Leu Ala Pro Arg Val Arg Ala Pro Gly Leu Leu Asp Ser Leu Tyr
     50                  55                  60

Gly Thr Val Arg Arg Phe Leu Ser Val Val Gln Leu Asn Pro Phe Pro
 65                  70                  75                  80

Ser Glu Leu Val Lys Ala Leu Leu Asn Glu Leu Ala Phe Val Lys Val
                 85                  90                  95

Asn Glu Val Val Arg Tyr Glu Ala Gly Tyr Val Val Cys Ala Val Ile
            100                 105                 110

Ala Gly Leu Tyr Leu Leu Leu Val Pro Thr Ala Gly Leu Cys Phe Cys
        115                 120                 125

Cys Cys Arg Cys His Arg Arg Cys Gly Gly Arg Val Lys Thr Glu His
    130                 135                 140

Lys Ala Leu Ala Cys Glu Arg Ala Ala Leu Met Val Phe Leu Leu Leu
145                 150                 155                 160

Thr Thr Leu Leu Leu Leu Ile Gly Val Val Cys Ala Phe Val Thr Asn
                165                 170                 175

Gln Arg Thr His Glu Gln Met Gly Pro Ser Ile Glu Ala Met Pro Glu
            180                 185                 190

Thr Leu Leu Ser Leu Trp Gly Leu Val Ser Asp Val Pro Gln Glu Leu
        195                 200                 205

Gln Ala Val Ala Gln Gln Phe Ser Leu Pro Gln Glu Gln Val Ser Glu
    210                 215                 220

Glu Leu Asp Gly Val Gly Val Ser Ile Gly Ser Ala Ile His Thr Gln
225                 230                 235                 240

Leu Arg Ser Ser Val Tyr Pro Leu Leu Ala Ala Val Gly Ser Leu Gly
                245                 250                 255

Gln Val Leu Gln Val Ser Val His His Leu Gln Thr Leu Asn Ala Thr
            260                 265                 270

Val Val Glu Leu Gln Ala Gly Gln Gln Asp Leu Glu Pro Ala Ile Arg
        275                 280                 285

Glu His Arg Asp Arg Leu Leu Glu Leu Leu Gln Glu Ala Arg Cys Gln
    290                 295                 300

Gly Asp Cys Ala Gly Ala Leu Ser Trp Ala Arg Thr Leu Glu Leu Gly
305                 310                 315                 320

Ala Asp Phe Ser Gln Val Pro Ser Val Asp His Val Leu His Gln Leu
                325                 330                 335

Lys Gly Val Pro Glu Ala Asn Phe Ser Ser Met Val Gln Glu Glu Asn
            340                 345                 350

Ser Thr Phe Asn Ala Leu Pro Ala Leu Ala Ala Met Gln Thr Ser Ser
        355                 360                 365

Val Val Gln Glu Leu Lys Lys Ala Val Ala Gln Gln Pro Glu Gly Val
    370                 375                 380

Arg Thr Leu Ala Glu Gly Phe Pro Gly Leu Glu Ala Ala Ser Arg Trp
385                 390                 395                 400

Ala Gln Ala Leu Gln Glu Val Glu Glu Ser Ser Arg Pro Tyr Leu Gln
                405                 410                 415

Glu Val Gln Arg Tyr Glu Thr Tyr Arg Trp Ile Val Gly Cys Val Leu
            420                 425                 430

Cys Ser Val Val Leu Phe Val Val Leu Cys Asn Leu Leu Gly Leu Asn
        435                 440                 445

Leu Gly Ile Trp Gly Leu Ser Ala Arg Asp Asp Pro Ser His Pro Glu
    450                 455                 460

Ala Lys Gly Glu Ala Gly Ala Arg Phe Leu Met Ala Gly Val Gly Leu
465                 470                 475                 480

Ser Phe Leu Phe Ala Ala Pro Leu Ile Leu Leu Val Phe Ala Thr Phe
                485                 490                 495

Leu Val Gly Gly Asn Val Gln Thr Leu Val Cys Arg Ser Trp Glu Asn
            500                 505                 510

Gly Glu Leu Phe Glu Phe Ala Asp Thr Pro Gly Asn Leu Pro Pro Ser
        515                 520                 525

Met Asn Leu Ser Gln Leu Leu Gly Leu Arg Lys Asn Ile Ser Ile His
    530                 535                 540

Gln Ala Tyr Gln Gln Cys Lys Glu Gly Ala Ala Leu Trp Thr Val Leu
545                 550                 555                 560

Gln Leu Asn Asp Ser Tyr Asp Leu Glu Glu His Leu Asp Ile Asn Gln
                565                 570                 575

Tyr Thr Asn Lys Leu Arg Gln Glu Leu Gln Ser Leu Lys Val Asp Thr
            580                 585                 590

Gln Ser Leu Asp Leu Leu Ser Ser Ala Ala Arg Arg Asp Leu Glu Ala
        595                 600                 605

Leu Gln Ser Ser Gly Leu Gln Arg Ile His Tyr Pro Asp Phe Leu Val
    610                 615                 620

Gln Ile Gln Arg Pro Val Val Lys Thr Ser Met Glu Gln Leu Ala Gln
625                 630                 635                 640

Glu Leu Gln Gly Leu Ala Gln Ala Gln Asp Asn Ser Val Leu Gly Gln
                645                 650                 655

Arg Leu Gln Glu Glu Ala Gln Gly Leu Arg Asn Leu His Gln Glu Lys
            660                 665                 670

Val Val Pro Gln Gln Ser Leu Val Ala Lys Leu Asn Leu Ser Val Arg
        675                 680                 685

Ala Leu Glu Ser Ser Ala Pro Asn Leu Gln Leu Glu Thr Ser Asp Val
    690                 695                 700

Leu Ala Asn Val Thr Tyr Leu Lys Gly Glu Leu Pro Ala Trp Ala Ala
705                 710                 715                 720

Arg Ile Leu Arg Asn Val Ser Glu Cys Phe Leu Ala Arg Glu Met Gly
                725                 730                 735

Tyr Phe Ser Gln Tyr Val Ala Trp Val Arg Glu Glu Val Thr Gln Arg
            740                 745                 750

Ile Ala Thr Cys Gln Pro Leu Ser Gly Ala Leu Asp Asn Ser Arg Val
        755                 760                 765

Ile Leu Cys Asp Met Met Ala Asp Pro Trp Asn Ala Phe Trp Phe Cys
    770                 775                 780

Leu Ala Trp Cys Thr Phe Phe Leu Ile Pro Ser Ile Ile Phe Ala Val
785                 790                 795                 800

Lys Thr Ser Lys Tyr Phe Arg Pro Ile Arg Lys Arg Leu Ser Ser Thr
                805                 810                 815

Ser Ser Glu Glu Thr Gln Leu Phe His Ile Pro Arg Val Thr Ser Leu
            820                 825                 830

Lys Leu 




<210> 2620
<211> 161
<212> PRT
<213> Homo sapiens

<400> 2620
Met Thr Pro Arg Val Pro Met Glu Arg Glu Leu Ser Phe Tyr Gly Leu
  1               5                  10                  15

Thr Ala Leu Ala Leu Met Leu Gly Thr Ser Leu Ile Tyr Trp Thr Leu
             20                  25                  30

Phe Thr Leu Gly Leu Asp Leu Ser Trp Ser Ile Ser Leu Ala Phe Lys
         35                  40                  45

Trp Cys Glu Arg Pro Glu Trp Ile His Val Asp Ser Arg Pro Phe Ala
     50                  55                  60

Ser Leu Ser Arg Asp Ser Gly Ala Ala Leu Gly Leu Gly Ile Ala Leu
 65                  70                  75                  80

His Ser Pro Cys Tyr Ala Gln Val Arg Arg Ala Gln Leu Gly Asn Gly
                 85                  90                  95

Gln Lys Ile Ala Cys Leu Val Leu Ala Met Gly Leu Leu Gly Pro Leu
            100                 105                 110

Asp Trp Leu Gly His Pro Pro Gln Ile Ser Leu Phe Tyr Ile Phe Asn
        115                 120                 125

Phe Leu Lys Tyr Thr Leu Trp Pro Cys Leu Val Leu Ala Leu Val Pro
    130                 135                 140

Trp Ala Val His Met Phe Ser Ala Gln Glu Ala Pro Pro Ile His Ser
145                 150                 155                 160

Ser 




<210> 2621
<211> 603
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (390)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2621
Met Leu Ser Leu Tyr Glu Lys Ile Lys Ile Arg Leu Ile Ile Leu Phe
  1               5                  10                  15

Leu Leu Ala Ala Leu Ser Phe Ile Gly Leu Phe Phe Ile Ile Asn Tyr
             20                  25                  30

Gln Leu Val Ser Glu Arg Ala Val Lys Arg Ala Asp Ser Arg Phe Glu
         35                  40                  45

Leu Ile Gln Lys Asn Val Gly Tyr Phe Phe Lys Asp Ile Glu Arg Ser
     50                  55                  60

Ala Leu Thr Leu Lys Asp Ser Leu Tyr Leu Leu Lys Asn Thr Glu Glu
 65                  70                  75                  80

Ile Gln Arg Ala Val Ile Leu Lys Met Glu Met Met Pro Phe Leu Asp
                 85                  90                  95

Ser Val Gly Leu Val Leu Asp Asp Asn Lys Tyr Tyr Leu Phe Ser Arg
            100                 105                 110

Arg Ala Asn Asp Lys Ile Val Val Tyr His Gln Glu Gln Val Asn Gly
        115                 120                 125

Pro Leu Val Asp Glu Ser Gly Arg Val Ile Phe Ala Asp Phe Asn Pro
    130                 135                 140

Ser Lys Arg Pro Trp Ser Val Ala Ser Asp Asp Ser Asn Asn Ser Trp
145                 150                 155                 160

Asn Pro Ala Tyr Asn Cys Phe Asp Arg Pro Gly Lys Lys Xaa Ile Ser
                165                 170                 175

Phe Thr Leu His Ile Asn Gly Lys Asp His Asp Leu Leu Ala Val Asp
            180                 185                 190

Lys Ile His Val Asp Leu Asn Trp Arg Tyr Leu Asn Glu Tyr Leu Asp
        195                 200                 205

Gln Ile Ser Ala Asn Asp Glu Val Leu Phe Leu Lys Gln Gly His Glu
    210                 215                 220

Ile Ile Ala Lys Asn Gln Leu Ala Arg Glu Lys Leu Ile Ile Tyr Asn
225                 230                 235                 240

Ser Glu Gly Asn Tyr Asn Ile Ile Asp Ser Val Asp Thr Glu Tyr Ile
                245                 250                 255

Glu Lys Thr Ser Ala Val Pro Asn Asn Ala Leu Phe Glu Ile Tyr Phe
            260                 265                 270

Tyr Tyr Pro Gly Gly Asn Leu Leu Asn Ala Ser Asp Lys Leu Phe Tyr
        275                 280                 285

Leu Pro Phe Ala Phe Ile Ile Ile Val Leu Leu Val Val Tyr Leu Met
    290                 295                 300

Thr Thr Arg Val Phe Arg Arg Gln Phe Ser Glu Met Thr Glu Leu Val
305                 310                 315                 320

Asn Thr Leu Ala Phe Leu Pro Asp Ser Thr Asp Gln Ile Glu Ala Leu
                325                 330                 335

Lys Ile Arg Glu Gly Asp Ala Lys Glu Ile Ile Ser Ile Lys Asn Ser
            340                 345                 350

Ile Ala Glu Met Lys Asp Ala Glu Ile Glu Arg Ser Asn Lys Leu Leu
        355                 360                 365

Ser Leu Ile Ser Tyr Asp Gln Glu Ser Gly Phe Ile Lys Asn Met Ala
    370                 375                 380

Ile Ile Glu Ser Asn Xaa Asn Gln Tyr Leu Ala Val Gly Ile Ile Lys
385                 390                 395                 400

Leu Cys Gly Leu Glu Ala Val Glu Ala Val Phe Gly Val Asp Glu Arg
                405                 410                 415

Asn Lys Ile Val Arg Lys Leu Cys Gln Arg Ile Ala Glu Lys Tyr Ala
            420                 425                 430

Gln Cys Cys Asp Ile Val Thr Phe Asn Ala Asp Leu Tyr Leu Leu Leu
        435                 440                 445

Cys Arg Glu Asn Val Gln Thr Phe Thr Arg Lys Ile Ala Met Val Asn
    450                 455                 460

Asp Phe Asp Ser Ser Phe Gly Tyr Arg Asn Leu Arg Ile His Lys Ser
465                 470                 475                 480

Ala Ile Cys Glu Pro Leu Gln Gly Glu Asn Ala Trp Ser Tyr Ala Glu
                485                 490                 495

Lys Leu Lys Leu Ala Ile Ser Ser Ile Arg Asp His Met Phe Ser Glu
            500                 505                 510

Phe Ile Phe Cys Asp Asp Ala Lys Leu Asn Glu Ile Glu Glu Asn Ile
        515                 520                 525

Trp Ile Ala Arg Asn Ile Arg His Ala Met Glu Ile Gly Glu Leu Phe
    530                 535                 540

Leu Val Tyr Gln Pro Ile Val Asp Ile Asn Thr Arg Ala Ile Leu Gly
545                 550                 555                 560

Ala Glu Ala Leu Cys Arg Trp Val Ser Ala Glu Arg Gly Ile Ile Ser
                565                 570                 575

Pro Leu Lys Phe Ile Thr Ile Ala Glu Asp Ile Gly Phe Ile Asn Glu
            580                 585                 590

Leu Gly Tyr Gln Ile Ile Lys Thr Ala Met Gly 
        595                 600



<210> 2622
<211> 172
<212> PRT
<213> Homo sapiens

<400> 2622
Met Asp Ser Pro Ser Leu Arg Glu Leu Gln Gln Pro Leu Leu Glu Gly
  1               5                  10                  15

Thr Glu Cys Glu Thr Pro Ala Gln Lys Pro Gly Arg His Glu Leu Gly
             20                  25                  30

Ser Pro Leu Arg Glu Ile Ala Phe Ala Glu Ser Leu Arg Gly Leu Gln
         35                  40                  45

Phe Leu Ser Pro Pro Leu Pro Ser Val Ser Ala Gly Leu Gly Glu Pro
     50                  55                  60

Arg Pro Pro Asp Val Glu Asp Met Ser Ser Ser Asp Ser Asp Ser Asp
 65                  70                  75                  80

Trp Asp Gly Gly Ser Arg Leu Ser Pro Phe Leu Pro His Asp His Leu
                 85                  90                  95

Gly Leu Ala Val Phe Ser Met Leu Cys Cys Phe Trp Pro Val Gly Ile
            100                 105                 110

Ala Ala Phe Cys Leu Ala Gln Lys Thr Asn Lys Ala Trp Ala Lys Gly
        115                 120                 125

Asp Ile Gln Gly Ala Gly Ala Ala Ser Arg Arg Ala Phe Leu Leu Gly
    130                 135                 140

Val Leu Ala Val Gly Leu Gly Val Cys Thr Tyr Ala Ala Ala Leu Val
145                 150                 155                 160

Thr Leu Ala Ala Tyr Leu Ala Ser Arg Asp Pro Pro 
                165                 170



<210> 2623
<211> 107
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (24)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (28)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (35)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2623
Met Arg Ser Pro Met Arg Trp Ala Thr Leu Pro Ser Cys Ser Gly Pro
  1               5                  10                  15

Ala Leu Thr Asp Gly Ala Ser Xaa Ala Ala Thr Xaa Asn Ser Ala Gly
             20                  25                  30

Gly Pro Xaa Gly Pro Leu Phe Ala Ile Cys Thr Gln Ser Pro Lys Gly
         35                  40                  45

Val Glu Glu Thr Ala Ala Trp Val Leu Pro Phe Thr Ser Gly Gly Phe
     50                  55                  60

Leu Tyr Ile Ala Leu Val Asn Val Leu Pro Asp Leu Leu Glu Glu Glu
 65                  70                  75                  80

Asp Pro Trp Arg Ser Leu Gln Gln Leu Leu Leu Leu Cys Ala Gly Ile
                 85                  90                  95

Val Val Met Val Leu Phe Ser Leu Phe Val Asp 
            100                 105



<210> 2624
<211> 246
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (222)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (242)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (244)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2624
Met Gly Ala Ala Val Phe Phe Gly Cys Thr Phe Val Ala Phe Gly Pro
  1               5                  10                  15

Ala Phe Ala Leu Phe Leu Ile Thr Val Ala Gly Asp Pro Leu Arg Val
             20                  25                  30

Ile Ile Leu Val Ala Gly Ala Phe Phe Trp Leu Val Ser Leu Leu Leu
         35                  40                  45

Ala Ser Val Val Trp Phe Ile Leu Val His Val Thr Asp Arg Ser Asp
     50                  55                  60

Ala Arg Leu Gln Tyr Gly Leu Leu Ile Phe Gly Ala Ala Val Ser Val
 65                  70                  75                  80

Leu Leu Gln Glu Val Phe Arg Phe Ala Tyr Tyr Lys Leu Leu Lys Lys
                 85                  90                  95

Ala Asp Glu Gly Leu Ala Ser Leu Ser Glu Asp Gly Arg Ser Pro Ile
            100                 105                 110

Ser Ile Arg Gln Met Ala Tyr Val Ser Gly Leu Ser Phe Gly Ile Ile
        115                 120                 125

Ser Gly Val Phe Ser Val Ile Asn Ile Leu Ala Asp Ala Leu Gly Pro
    130                 135                 140

Gly Val Val Gly Ile His Gly Asp Ser Pro Tyr Tyr Phe Leu Thr Ser
145                 150                 155                 160

Ala Phe Leu Thr Ala Ala Ile Ile Leu Leu His Thr Phe Trp Gly Val
                165                 170                 175

Val Phe Phe Asp Ala Cys Glu Arg Arg Arg Tyr Trp Ala Leu Gly Leu
            180                 185                 190

Val Val Gly Ser His Leu Leu Thr Ser Gly Leu Thr Phe Leu Asn Pro
        195                 200                 205

Trp Tyr Glu Ala Ser Leu Leu Pro Ser Met Gln Ser Leu Xaa Xaa Trp
    210                 215                 220

Gly Ser Gly Pro Ser Ser Gln Leu Glu Gly Pro Xaa Lys Tyr Ser Ala
225                 230                 235                 240

Gln Xaa Leu Xaa Lys Asp 
                245



<210> 2625
<211> 389
<212> PRT
<213> Homo sapiens

<400> 2625
Met Trp Ile Lys Phe Ser Ser Asp Glu Glu Leu Glu Gly Leu Gly Phe
  1               5                  10                  15

Arg Ala Lys Tyr Ser Phe Ile Pro Asp Pro Asp Phe Thr Tyr Leu Gly
             20                  25                  30

Gly Ile Leu Asn Pro Ile Pro Asp Cys Gln Phe Glu Leu Ser Gly Ala
         35                  40                  45

Asp Gly Ile Val Arg Ser Ser Gln Val Glu Gln Glu Glu Lys Thr Lys
     50                  55                  60

Pro Gly Gln Ala Val Asp Cys Ile Trp Thr Ile Lys Ala Thr Pro Lys
 65                  70                  75                  80

Ala Lys Ile Tyr Leu Arg Phe Leu Asp Tyr Gln Met Glu His Ser Asn
                 85                  90                  95

Glu Cys Lys Arg Asn Phe Val Ala Val Tyr Asp Gly Ser Ser Ser Ile
            100                 105                 110

Glu Asn Leu Lys Ala Lys Phe Cys Ser Thr Val Ala Asn Asp Val Met
        115                 120                 125

Leu Lys Thr Gly Ile Gly Val Ile Arg Met Trp Ala Asp Glu Gly Ser
    130                 135                 140

Arg Leu Ser Arg Phe Arg Met Leu Phe Thr Ser Phe Val Glu Pro Pro
145                 150                 155                 160

Cys Thr Ser Ser Thr Phe Phe Cys His Ser Asn Met Cys Ile Asn Asn
                165                 170                 175

Ser Leu Val Cys Asn Gly Val Gln Asn Cys Ala Tyr Pro Trp Asp Glu
            180                 185                 190

Asn His Cys Lys Glu Lys Lys Lys Ala Gly Val Phe Glu Gln Ile Thr
        195                 200                 205

Lys Thr His Gly Thr Ile Ile Gly Ile Thr Ser Gly Ile Val Leu Val
    210                 215                 220

Leu Leu Ile Ile Ser Ile Leu Val Gln Val Lys Gln Pro Arg Lys Lys
225                 230                 235                 240

Val Met Ala Cys Lys Thr Ala Phe Asn Lys Thr Gly Phe Gln Glu Val
                245                 250                 255

Phe Asp Pro Pro His Tyr Glu Leu Phe Ser Leu Arg Asp Lys Glu Ile
            260                 265                 270

Ser Ala Asp Leu Ala Asp Leu Ser Glu Glu Leu Asp Asn Tyr Gln Lys
        275                 280                 285

Met Arg Arg Ser Ser Thr Ala Ser Arg Cys Ile His Asp His His Cys
    290                 295                 300

Gly Ser Gln Ala Ser Ser Val Lys Gln Ser Arg Thr Asn Leu Ser Ser
305                 310                 315                 320

Met Glu Leu Pro Phe Arg Asn Asp Phe Ala Gln Pro Gln Pro Met Lys
                325                 330                 335

Thr Phe Asn Ser Thr Phe Lys Lys Ser Ser Tyr Thr Phe Lys Gln Gly
            340                 345                 350

His Glu Cys Pro Glu Gln Ala Leu Glu Asp Arg Val Met Glu Glu Ile
        355                 360                 365

Pro Cys Glu Ile Tyr Val Arg Gly Arg Glu Asp Ser Ala Gln Ala Ser
    370                 375                 380

Ile Ser Ile Asp Phe 
385



<210> 2626
<211> 258
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (3)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (182)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2626
Met Leu Xaa Ala Asn Pro Pro Pro Phe Lys Ser Val Trp Ser Arg Leu
  1               5                  10                  15

Asp Gly Gln Trp Pro Asp Gly Leu Leu Ala Ser Asp Asn Thr Leu His
             20                  25                  30

Phe Val His Pro Leu Thr Phe Asn Tyr Ser Gly Val Tyr Ile Cys Lys
         35                  40                  45

Val Thr Asn Ser Leu Gly Gln Arg Ser Asp Gln Lys Val Ile Tyr Ile
     50                  55                  60

Ser Asp Pro Pro Thr Thr Thr Thr Leu Gln Pro Thr Ile Gln Trp His
 65                  70                  75                  80

Pro Ser Thr Ala Asp Ile Glu Asp Leu Ala Thr Glu Pro Lys Lys Leu
                 85                  90                  95

Pro Phe Pro Leu Ser Thr Leu Ala Thr Ile Lys Asp Asp Thr Ile Ala
            100                 105                 110

Thr Ile Ile Ala Ser Val Val Gly Gly Ala Leu Phe Ile Val Leu Val
        115                 120                 125

Ser Val Leu Ala Gly Ile Phe Cys Tyr Arg Arg Arg Arg Thr Phe Arg
    130                 135                 140

Gly Asp Tyr Phe Ala Lys Asn Tyr Ile Pro Pro Ser Asp Met Gln Lys
145                 150                 155                 160

Glu Ser Gln Ile Asp Val Leu Gln Gln Asp Glu Leu Asp Ser Tyr Pro
                165                 170                 175

Asp Ser Val Lys Lys Xaa Asn Lys Asn Pro Val Asn Asn Leu Ile Arg
            180                 185                 190

Lys Asp Tyr Leu Glu Glu Pro Glu Lys Thr Gln Trp Asn Asn Val Glu
        195                 200                 205

Asn Leu Asn Arg Phe Glu Arg Pro Met Asp Tyr Tyr Glu Asp Leu Lys
    210                 215                 220

Met Gly Met Lys Phe Val Ser Asp Glu His Tyr Asp Glu Asn Glu Asp
225                 230                 235                 240

Asp Leu Val Ser His Val Asp Gly Ser Val Ile Ser Arg Arg Glu Trp
                245                 250                 255

Tyr Val 




<210> 2627
<211> 284
<212> PRT
<213> Homo sapiens

<400> 2627
Met Pro Arg Tyr Ala Gln Leu Val Met Gly Pro Ala Gly Ser Gly Lys
  1               5                  10                  15

Ser Thr Tyr Cys Ala Thr Met Val Gln His Cys Glu Ala Leu Asn Arg
             20                  25                  30

Ser Val Gln Val Val Asn Leu Asp Pro Ala Ala Glu His Phe Asn Tyr
         35                  40                  45

Ser Val Met Ala Asp Ile Arg Glu Leu Ile Glu Val Asp Asp Val Met
     50                  55                  60

Glu Asp Asp Ser Leu Arg Phe Gly Pro Asn Gly Gly Leu Val Phe Cys
 65                  70                  75                  80

Met Glu Tyr Phe Ala Asn Asn Phe Asp Trp Leu Glu Asn Cys Leu Gly
                 85                  90                  95

His Val Glu Asp Asp Tyr Ile Leu Phe Asp Cys Pro Gly Gln Ile Glu
            100                 105                 110

Leu Tyr Thr His Leu Pro Val Met Lys Gln Leu Val Gln Gln Leu Glu
        115                 120                 125

Gln Trp Glu Phe Arg Val Cys Gly Val Phe Leu Val Asp Ser Gln Phe
    130                 135                 140

Met Val Glu Ser Phe Lys Phe Ile Ser Gly Ile Leu Ala Ala Leu Ser
145                 150                 155                 160

Ala Met Ile Ser Leu Glu Ile Pro Gln Val Asn Ile Met Thr Lys Met
                165                 170                 175

Asp Leu Leu Ser Lys Lys Ala Lys Lys Glu Ile Glu Lys Phe Leu Asp
            180                 185                 190

Pro Asp Met Tyr Ser Leu Leu Glu Asp Ser Thr Ser Asp Leu Arg Ser
        195                 200                 205

Lys Lys Phe Lys Lys Leu Thr Lys Ala Ile Cys Gly Leu Ile Asp Asp
    210                 215                 220

Tyr Ser Met Val Arg Phe Leu Pro Tyr Asp Gln Ser Asp Glu Glu Ser
225                 230                 235                 240

Met Asn Ile Val Leu Gln His Ile Asp Phe Ala Ile Gln Tyr Gly Glu
                245                 250                 255

Asp Leu Glu Phe Lys Glu Pro Lys Glu Arg Glu Asp Glu Ser Ser Ser
            260                 265                 270

Met Phe Asp Glu Tyr Phe Gln Glu Cys Gln Asp Glu 
        275                 280



<210> 2628
<211> 469
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (396)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (405)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (410)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (466)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2628
Met Ala Asn Ala Glu Val Ser Val Pro Val Gly Asp Val Val Val Val
  1               5                  10                  15

Pro Thr Glu Gly Asn Glu Gly Glu Asn Pro Glu Asp Thr Lys Thr Gln
             20                  25                  30

Val Ile Leu Gln Leu Gln Pro Val Gln Gln Gly Ile Tyr Glu Ala Gly
         35                  40                  45

Ser Glu Asn Asn Thr Ala Val Val Ala Val Glu Thr His Thr Ile His
     50                  55                  60

Lys Ile Glu Glu Gly Ile Asp Thr Gly Thr Ile Glu Ala Asn Glu Asp
 65                  70                  75                  80

Met Glu Ile Ala Tyr Pro Ile Thr Cys Gly Glu Ser Lys Ala Ile Leu
                 85                  90                  95

Leu Trp Lys Lys Phe Val Cys Pro Gly Ile Asn Val Lys Cys Val Lys
            100                 105                 110

Phe Asn Asp Gln Leu Ile Ser Pro Lys His Phe Val His Leu Ala Gly
        115                 120                 125

Lys Ser Thr Leu Lys Asp Trp Lys Arg Ala Ile Arg Leu Gly Gly Ile
    130                 135                 140

Met Leu Arg Lys Met Met Asp Ser Gly Gln Ile Asp Phe Tyr Gln His
145                 150                 155                 160

Asp Lys Val Cys Ser Asn Thr Cys Arg Ser Thr Lys Phe Asp Leu Leu
                165                 170                 175

Ile Ser Ser Ala Arg Ala Pro Val Pro Gly Gln Gln Thr Ser Val Val
            180                 185                 190

Gln Thr Pro Thr Ser Ala Asp Gly Ser Ile Thr Gln Ile Ala Ile Ser
        195                 200                 205

Glu Glu Ser Met Glu Glu Ala Gly Leu Glu Trp Asn Ser Ala Leu Thr
    210                 215                 220

Ala Ala Val Thr Met Ala Thr Glu Glu Gly Val Lys Lys Asp Ser Glu
225                 230                 235                 240

Glu Ile Ser Glu Asp Thr Leu Met Phe Trp Lys Gly Ile Ala Asp Val
                245                 250                 255

Gly Leu Met Glu Glu Val Val Cys Asn Ile Gln Lys Glu Ile Glu Glu
            260                 265                 270

Leu Leu Arg Gly Val Gln Gln Arg Leu Ile Gln Ala Pro Phe Gln Val
        275                 280                 285

Thr Asp Ala Ala Val Leu Asn Asn Val Ala His Thr Phe Gly Leu Met
    290                 295                 300

Asp Thr Val Lys Lys Val Leu Asp Asn Arg Arg Asn Gln Val Glu Gln
305                 310                 315                 320

Gly Glu Glu Gln Phe Leu Tyr Thr Leu Thr Asp Leu Glu Arg Gln Leu
                325                 330                 335

Glu Glu Gln Lys Lys Gln Gly Gln Asp His Arg Leu Lys Ser Gln Thr
            340                 345                 350

Val Gln Asn Val Val Leu Met Pro Val Ser Thr Pro Lys Pro Pro Lys
        355                 360                 365

Arg Pro Arg Leu Gln Arg Pro Ala Ser Thr Thr Val Leu Ser Pro Ser
    370                 375                 380

Pro Pro Val Gln Gln Pro Gln Phe Thr Val Ile Xaa Pro Ile His His
385                 390                 395                 400

His Pro Ser Gly Xaa Ser His Phe Ser Xaa Gly Gln Tyr Phe Gln Trp
                405                 410                 415

Ala Thr Leu Ser Gln Gly Leu Gln Phe Leu Trp Thr Val Pro His Ile
            420                 425                 430

Ala Phe Leu Gly Leu Gln Val Phe Ser Val Met Ala Thr Val Gly Phe
        435                 440                 445

Ser Phe Trp Pro Arg Arg Gln Val Leu Thr Arg Thr Gln Leu Asn His
    450                 455                 460

Ser Xaa Leu Ser Phe 
465



<210> 2629
<211> 279
<212> PRT
<213> Homo sapiens

<400> 2629
Met Glu Cys Asp Asp Leu Lys Glu Leu Pro Glu Pro Thr Pro Val Lys
  1               5                  10                  15

Thr Arg Leu Pro Pro Glu Ile Phe Gly Asp Ala Leu Met Val Leu Glu
             20                  25                  30

Phe Leu Asn Ala Phe Gly Glu Leu Phe Asp Leu Gln Asp Glu Phe Pro
         35                  40                  45

Asp Gly Val Thr Leu Glu Val Leu Glu Glu Ala Leu Val Gly Asn Asp
     50                  55                  60

Ser Glu Gly Pro Leu Cys Glu Leu Leu Phe Phe Phe Leu Thr Ala Ile
 65                  70                  75                  80

Phe Gln Ala Ile Ala Glu Glu Glu Glu Glu Val Ala Lys Glu Gln Leu
                 85                  90                  95

Thr Asp Ala Asp Thr Lys Asp Leu Thr Glu Ala Leu Asp Glu Asp Ala
            100                 105                 110

Asp Pro Thr Lys Ser Ala Leu Ser Ala Val Ala Ser Leu Ala Ala Ala
        115                 120                 125

Trp Pro Gln Leu His Gln Gly Cys Ser Leu Lys Ser Leu Asp Leu Asp
    130                 135                 140

Ser Cys Thr Leu Ser Glu Ile Leu Arg Leu His Ile Leu Ala Ser Gly
145                 150                 155                 160

Ala Asp Val Thr Ser Ala Asn Ala Lys Tyr Arg Tyr Gln Lys Arg Gly
                165                 170                 175

Gly Phe Asp Ala Thr Asp Asp Ala Cys Met Glu Leu Arg Leu Ser Asn
            180                 185                 190

Pro Ser Leu Val Lys Lys Leu Ser Ser Thr Ser Val Tyr Asp Leu Thr
        195                 200                 205

Pro Gly Glu Lys Met Lys Ile Leu His Ala Leu Cys Gly Lys Leu Leu
    210                 215                 220

Thr Leu Val Ser Thr Arg Asp Phe Ile Glu Asp Tyr Val Asp Ile Leu
225                 230                 235                 240

Arg Gln Ala Lys Gln Glu Phe Arg Glu Leu Lys Ala Glu Gln His Arg
                245                 250                 255

Lys Glu Arg Glu Glu Ala Ala Ala Arg Ile Arg Lys Arg Lys Glu Glu
            260                 265                 270

Lys Leu Lys Glu Gln Ser Tyr 
        275



<210> 2630
<211> 269
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (173)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (184)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (201)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (217)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (236)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (246)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (254)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2630
Met Glu Val Pro Pro Pro Ala Pro Arg Ser Phe Leu Cys Arg Ala Leu
  1               5                  10                  15

Cys Leu Phe Pro Arg Val Phe Ala Ala Glu Ala Val Thr Ala Asp Ser
             20                  25                  30

Glu Val Leu Glu Glu Arg Gln Lys Arg Leu Pro Tyr Val Pro Glu Pro
         35                  40                  45

Tyr Tyr Pro Glu Ser Gly Trp Asp Arg Leu Arg Glu Leu Phe Gly Lys
     50                  55                  60

Asp Glu Gln Gln Arg Ile Ser Lys Asp Leu Ala Asn Ile Cys Lys Thr
 65                  70                  75                  80

Ala Ala Thr Ala Gly Ile Ile Gly Trp Val Tyr Gly Gly Ile Pro Ala
                 85                  90                  95

Phe Ile His Ala Lys Gln Gln Tyr Ile Glu Gln Ser Gln Ala Glu Ile
            100                 105                 110

Tyr His Asn Arg Phe Asp Ala Val Gln Ser Ala His Arg Ala Ala Thr
        115                 120                 125

Arg Gly Phe Ile Arg Tyr Gly Trp Arg Trp Gly Trp Arg Thr Ala Val
    130                 135                 140

Phe Val Thr Ile Phe Asn Thr Val Asn Thr Ser Leu Asn Val Tyr Arg
145                 150                 155                 160

Asn Lys Asp Ala Leu Ser His Phe Val Ile Ala Gly Xaa Val Thr Gly
                165                 170                 175

Ser Leu Phe Arg Ile Asn Val Xaa Leu Arg Gly Leu Val Ala Gly Gly
            180                 185                 190

Ile Ile Gly Ala Leu Leu Gly Thr Xaa Val Gly Gly Leu Leu Met Ala
        195                 200                 205

Phe Gln Lys Tyr Ser Gly Glu Thr Xaa Gln Glu Arg Lys Gln Lys Asp
    210                 215                 220

Arg Lys Ala Leu His Glu Leu Lys Leu Glu Glu Xaa Lys Ala Asp Tyr
225                 230                 235                 240

Lys Leu Leu Ser Thr Xaa Leu Arg Lys Leu Lys Val Val Xaa Arg Lys
                245                 250                 255

Met Asn Leu Arg Met Met Leu Arg Lys Leu Lys His Cys 
            260                 265



<210> 2631
<211> 666
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (254)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (347)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2631
Met Lys Pro Asp Ile Val Thr Tyr Gly Ala Gly Val Arg Gly Ser Gly
  1               5                  10                  15

Val Lys Gly Gly Cys Arg Ala Leu Ser Gly Thr Ser Val Ala Ser Pro
             20                  25                  30

Val Val Ala Gly Ala Val Thr Leu Leu Val Ser Thr Val Gln Lys Arg
         35                  40                  45

Glu Leu Val Asn Pro Ala Ser Met Lys Xaa Ala Leu Ile Ala Ser Ala
     50                  55                  60

Arg Arg Leu Pro Gly Val Asn Met Phe Glu Gln Gly His Gly Lys Leu
 65                  70                  75                  80

Asp Leu Leu Arg Ala Tyr Gln Ile Leu Asn Ser Tyr Lys Pro Gln Ala
                 85                  90                  95

Ser Leu Ser Pro Ser Tyr Ile Asp Leu Thr Glu Cys Pro Tyr Met Trp
            100                 105                 110

Pro Tyr Cys Ser Gln Pro Ile Tyr Tyr Gly Gly Met Pro Thr Val Val
        115                 120                 125

Asn Val Thr Ile Leu Asn Gly Met Gly Val Thr Gly Arg Ile Val Asp
    130                 135                 140

Lys Pro Asp Trp Gln Pro Tyr Leu Pro Gln Asn Gly Asp Asn Ile Glu
145                 150                 155                 160

Val Ala Phe Ser Tyr Ser Ser Val Leu Trp Pro Trp Ser Gly Tyr Leu
                165                 170                 175

Ala Ile Ser Ile Ser Val Thr Lys Lys Ala Ala Ser Trp Glu Gly Ile
            180                 185                 190

Ala Gln Gly His Val Met Ile Thr Val Ala Ser Pro Ala Glu Thr Glu
        195                 200                 205

Ser Lys Asn Gly Ala Glu Gln Thr Ser Thr Val Lys Leu Pro Ile Lys
    210                 215                 220

Val Lys Ile Ile Pro Thr Pro Pro Arg Ser Lys Arg Val Leu Trp Asp
225                 230                 235                 240

Gln Tyr His Asn Leu Arg Tyr Pro Pro Gly Tyr Phe Pro Xaa Asp Asn
                245                 250                 255

Leu Arg Met Lys Asn Asp Pro Leu Asp Trp Asn Gly Asp His Ile His
            260                 265                 270

Thr Asn Phe Arg Asp Met Tyr Gln His Leu Arg Ser Met Gly Tyr Phe
        275                 280                 285

Val Glu Val Leu Gly Ala Pro Phe Thr Cys Phe Asp Ala Ser Gln Tyr
    290                 295                 300

Gly Thr Leu Leu Met Val Asp Ser Glu Glu Glu Tyr Phe Pro Glu Glu
305                 310                 315                 320

Ile Ala Lys Leu Arg Arg Asp Val Asp Asn Gly Leu Ser Leu Val Ile
                325                 330                 335

Phe Ser Asp Trp Tyr Asn Thr Ser Val Met Xaa Lys Val Lys Phe Tyr
            340                 345                 350

Asp Glu Asn Thr Arg Gln Trp Trp Met Pro Asp Thr Gly Gly Ala Asn
        355                 360                 365

Ile Pro Ala Leu Asn Glu Leu Leu Ser Val Trp Asn Met Gly Phe Ser
    370                 375                 380

Asp Gly Leu Tyr Glu Gly Glu Phe Thr Leu Ala Asn His Asp Met Tyr
385                 390                 395                 400

Tyr Ala Ser Gly Cys Ser Ile Ala Lys Phe Pro Glu Asp Gly Val Val
                405                 410                 415

Ile Thr Gln Thr Phe Lys Asp Gln Gly Leu Glu Val Leu Lys Gln Glu
            420                 425                 430

Thr Ala Val Val Glu Asn Val Pro Ile Leu Gly Leu Tyr Gln Ile Pro
        435                 440                 445

Ala Glu Gly Gly Gly Arg Ile Val Leu Tyr Gly Asp Ser Asn Cys Leu
    450                 455                 460

Asp Asp Ser His Arg Gln Lys Asp Cys Phe Trp Leu Leu Asp Ala Leu
465                 470                 475                 480

Leu Gln Tyr Thr Ser Tyr Gly Val Thr Pro Pro Ser Leu Ser His Ser
                485                 490                 495

Gly Asn Arg Gln Arg Pro Pro Ser Gly Ala Gly Ser Val Thr Pro Glu
            500                 505                 510

Arg Met Glu Gly Asn His Leu His Arg Tyr Ser Lys Val Leu Glu Ala
        515                 520                 525

His Leu Gly Asp Pro Lys Pro Arg Pro Leu Pro Ala Cys Pro Arg Leu
    530                 535                 540

Ser Trp Ala Lys Pro Gln Pro Leu Asn Glu Thr Ala Pro Ser Asn Leu
545                 550                 555                 560

Trp Lys His Gln Lys Leu Leu Ser Ile Asp Leu Asp Lys Val Val Leu
                565                 570                 575

Pro Asn Phe Arg Ser Asn Arg Pro Gln Val Arg Pro Leu Ser Pro Gly
            580                 585                 590

Glu Ser Gly Ala Trp Asp Ile Pro Gly Gly Ile Met Pro Gly Arg Tyr
        595                 600                 605

Asn Gln Glu Val Gly Gln Thr Ile Pro Val Phe Ala Phe Leu Gly Ala
    610                 615                 620

Met Val Val Leu Ala Phe Phe Val Val Gln Ile Asn Lys Ala Lys Ser
625                 630                 635                 640

Arg Pro Lys Arg Arg Lys Pro Arg Val Lys Arg Pro Gln Leu Met Gln
                645                 650                 655

Gln Val His Pro Pro Lys Thr Pro Ser Val 
            660                 665



<210> 2632
<211> 240
<212> PRT
<213> Homo sapiens

<400> 2632
Met Arg Arg Cys Ser Leu Cys Ala Phe Asp Ala Ala Arg Gly Pro Arg
  1               5                  10                  15

Arg Leu Met Arg Val Gly Leu Ala Leu Ile Leu Val Gly His Val Asn
             20                  25                  30

Leu Leu Leu Gly Ala Val Leu His Gly Thr Val Leu Arg His Val Ala
         35                  40                  45

Asn Pro Arg Gly Ala Val Thr Pro Glu Tyr Thr Val Ala Asn Val Ile
     50                  55                  60

Ser Val Gly Ser Gly Leu Leu Ser Val Ser Val Gly Leu Val Ala Leu
 65                  70                  75                  80

Leu Ala Ser Arg Asn Leu Leu Arg Pro Pro Leu His Trp Val Leu Leu
                 85                  90                  95

Ala Leu Ala Leu Val Asn Leu Leu Leu Ser Val Ala Cys Ser Leu Gly
            100                 105                 110

Leu Leu Leu Ala Val Ser Leu Thr Val Ala Asn Gly Gly Arg Arg Leu
        115                 120                 125

Ile Ala Asp Cys His Pro Gly Leu Leu Asp Pro Leu Val Pro Leu Asp
    130                 135                 140

Glu Gly Pro Gly His Thr Asp Cys Pro Phe Asp Pro Thr Arg Ile Tyr
145                 150                 155                 160

Asp Thr Ala Leu Ala Leu Trp Ile Pro Ser Leu Leu Met Ser Ala Gly
                165                 170                 175

Glu Ala Ala Leu Ser Gly Tyr Cys Cys Val Ala Ala Leu Thr Leu Arg
            180                 185                 190

Gly Val Gly Pro Cys Arg Lys Asp Gly Leu Gln Gly Gln Leu Glu Glu
        195                 200                 205

Met Thr Glu Leu Glu Ser Pro Lys Cys Lys Arg Gln Glu Asn Glu Gln
    210                 215                 220

Leu Leu Asp Gln Asn Gln Glu Ile Arg Ala Ser Gln Arg Ser Trp Val
225                 230                 235                 240






<210> 2633
<211> 266
<212> PRT
<213> Homo sapiens

<400> 2633
Met Ala Ala Ala Ala Leu His Tyr Gly Trp Arg Ala Gly Met Met Ile
  1               5                  10                  15

Ala Gly Cys Met Ala Ile Val Val Gly Ile Phe Leu Cys Trp Arg Leu
             20                  25                  30

Arg Asp Arg Pro Gln Ala Leu Gly Leu Pro Ala Val Gly Glu Trp Arg
         35                  40                  45

His Asp Ala Leu Glu Ile Ala Gln Gln Gln Glu Gly Ala Gly Leu Thr
     50                  55                  60

Arg Lys Glu Ile Leu Thr Lys Tyr Val Leu Leu Asn Pro Tyr Ile Trp
 65                  70                  75                  80

Leu Leu Ser Phe Cys Tyr Val Leu Val Tyr Val Val Arg Ala Ala Ile
                 85                  90                  95

Asn Asp Trp Gly Asn Leu Tyr Met Ser Glu Thr Leu Gly Val Asp Leu
            100                 105                 110

Val Thr Ala Asn Thr Ala Val Thr Met Phe Glu Leu Gly Gly Phe Ile
        115                 120                 125

Gly Ala Leu Val Ala Gly Trp Gly Ser Asp Lys Leu Phe Asn Gly Asn
    130                 135                 140

Arg Gly Pro Met Asn Leu Ile Phe Ala Ala Gly Ile Leu Leu Ser Val
145                 150                 155                 160

Gly Ser Leu Trp Leu Met Pro Phe Ala Ser Tyr Val Met Gln Ala Thr
                165                 170                 175

Cys Phe Phe Thr Ile Gly Phe Phe Val Phe Gly Pro Gln Met Leu Ile
            180                 185                 190

Gly Met Ala Ala Ala Glu Cys Ser His Lys Glu Ala Ala Gly Ala Ala
        195                 200                 205

Thr Gly Phe Val Gly Leu Phe Ala Tyr Leu Gly Ala Ser Leu Ala Gly
    210                 215                 220

Trp Pro Leu Ala Lys Val Leu Asp Thr Trp His Trp Ser Gly Phe Phe
225                 230                 235                 240

Val Val Ile Ser Ile Ala Ala Gly Ile Ser Ala Leu Leu Leu Leu Pro
                245                 250                 255

Phe Leu Asn Ala Gln Thr Pro Arg Glu Ala 
            260                 265



<210> 2634
<211> 162
<212> PRT
<213> Homo sapiens

<400> 2634
Met Gly Gly Gly Val Gly Ser Ala Glu Tyr Val Ala Thr Phe Leu Tyr
  1               5                  10                  15

Arg Thr His Phe Phe Ala Pro Met Ser Ile Arg Ser Asp Lys Ile Lys
             20                  25                  30

Asp Ile Asn Leu Met Phe Pro Trp Pro Ala Leu Arg Cys Ala Gly Thr
         35                  40                  45

Asn Arg Leu Tyr Leu Leu Tyr Phe Phe Phe Pro Phe Phe Leu Lys Arg
     50                  55                  60

Ser Leu Ala Gln Ser Pro Arg Leu Glu Gly Ser Gly Ala Ile Ser Ala
 65                  70                  75                  80

His Cys Arg Leu Arg Leu Pro Gly Ser Arg Arg Ser Pro Ala Ser Ala
                 85                  90                  95

Ser Arg Ile Ala Gly Thr Thr Gly Ala Arg His Tyr Ala Arg Leu Ile
            100                 105                 110

Phe Cys Val Phe Leu Val Glu Ala Gly Phe His His Val Gly Leu Glu
        115                 120                 125

Leu Leu Thr Ser Gly Asp Pro Pro Ala Leu Ala Ser Gln Ser Ala Gly
    130                 135                 140

Ile Thr Gly Val Ser His Cys Val Arg Pro Leu Tyr Phe Phe Glu Leu
145                 150                 155                 160

Gln Thr 




<210> 2635
<211> 156
<212> PRT
<213> Homo sapiens

<400> 2635
Met Ala Phe Asn Ile Ile Ala Met Phe Phe Val Ile Ala Pro Asp Gln
  1               5                  10                  15

Gln Tyr Leu Arg Phe Ser Arg Leu Ala Val Leu Phe Arg Phe Val Met
             20                  25                  30

Thr Ser Pro Pro Ala Ser Cys Arg Ala Leu Ser Arg Gln Val Phe Gln
         35                  40                  45

Leu Lys Leu Glu Asn Ile Phe Asp Asn Arg Pro Phe Lys Ala Tyr Arg
     50                  55                  60

Val Ile Leu Phe Ser Leu Trp Thr Val Ala Gly His Met Leu Gly Gly
 65                  70                  75                  80

Val Ile Gln Pro Ala Asn Lys Gly Tyr Thr Arg Val Asp His His Asn
                 85                  90                  95

Phe Ala Met His Pro Ala Lys His Ile Gly Ala His Thr Lys Lys Ala
            100                 105                 110

Arg Ala Gly Ile Val Val Ala Glu His Tyr Ala Ser Cys Arg Gln Phe
        115                 120                 125

Ile Asp Lys Leu Ile Ala Glu Ile Arg Arg Thr Val Ala Ile Gln Gln
    130                 135                 140

Asp Phe Arg Phe Asn Pro Ala Leu Arg Cys Cys Gln 
145                 150                 155



<210> 2636
<211> 201
<212> PRT
<213> Homo sapiens

<400> 2636
Met Ser Thr Glu Ala Gln Arg Val Asp Asp Ser Pro Ser Thr Ser Gly
  1               5                  10                  15

Gly Ser Ser Asp Gly Asp Gln Arg Glu Ser Val Gln Gln Glu Pro Glu
             20                  25                  30

Arg Glu Gln Val Gln Pro Lys Lys Lys Glu Gly Lys Ile Ser Ser Lys
         35                  40                  45

Thr Ala Ala Lys Leu Ser Thr Ser Ala Lys Arg Ile Gln Lys Glu Leu
     50                  55                  60

Ala Glu Ile Thr Leu Asp Pro Pro Pro Asn Cys Ser Ala Gly Pro Lys
 65                  70                  75                  80

Gly Asp Asn Ile Tyr Glu Trp Arg Ser Thr Ile Leu Gly Pro Pro Gly
                 85                  90                  95

Ser Val Tyr Glu Gly Gly Val Phe Phe Leu Asp Ile Thr Phe Ser Pro
            100                 105                 110

Asp Tyr Pro Phe Lys Pro Pro Lys Val Thr Phe Arg Thr Arg Ile Tyr
        115                 120                 125

His Cys Asn Ile Asn Ser Gln Gly Val Ile Cys Leu Asp Ile Leu Lys
    130                 135                 140

Asp Asn Trp Ser Pro Ala Leu Thr Ile Ser Lys Val Leu Leu Ser Ile
145                 150                 155                 160

Cys Ser Leu Leu Thr Asp Cys Asn Pro Ala Asp Pro Leu Val Gly Ser
                165                 170                 175

Ile Ala Thr Gln Tyr Met Thr Asn Arg Ala Glu His Asp Arg Met Ala
            180                 185                 190

Arg Gln Trp Thr Lys Arg Tyr Ala Thr 
        195                 200



<210> 2637
<211> 108
<212> PRT
<213> Homo sapiens

<400> 2637
Met Phe Val Ser Val Thr Ala Phe Phe Phe Ser Leu Leu Phe Leu Gly
  1               5                  10                  15

Met Phe Leu Ser Gly Met Val Ala Gln Ile Asp Ala Asn Trp Asn Phe
             20                  25                  30

Leu Asp Phe Ala Tyr His Phe Thr Val Phe Val Phe Tyr Phe Gly Ala
         35                  40                  45

Phe Leu Leu Glu Ala Ala Ala Thr Ser Leu His Asp Leu His Cys Asn
     50                  55                  60

Thr Thr Ile Thr Gly Gln Pro Leu Leu Ser Asp Asn Gln Tyr Asn Ile
 65                  70                  75                  80

Asn Val Ala Ala Ser Ile Phe Ala Phe Met Thr Thr Ala Cys Tyr Gly
                 85                  90                  95

Cys Ser Leu Gly Leu Ala Leu Arg Arg Trp Arg Pro 
            100                 105



<210> 2638
<211> 244
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (164)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (179)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (185)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2638
Met Arg Leu Arg Phe Trp Leu Leu Ile Trp Leu Leu Leu Gly Phe Ile
  1               5                  10                  15

Ser His Gln Pro Thr Pro Val Ile Asn Thr Leu Ala Asp His Arg His
             20                  25                  30

Arg Glu Thr Asp Phe Gly Gly Ser Pro Trp Ile Ile Ile Ile Ile Val
         35                  40                  45

Phe Leu Gly Arg Tyr Lys Phe Thr Ile Leu Phe Cys Thr Ile Tyr Leu
     50                  55                  60

Cys Val Pro Phe Leu Lys Thr Ile Phe Trp Ser Arg Asn Gly His Asp
 65                  70                  75                  80

Arg Ser Arg Asp Val Gln Gln Arg Ala Arg Arg Ser Asn Arg Cys Arg
                 85                  90                  95

Gln Glu Gly Ile Lys Ile Gly Leu Glu Asp Ile Cys Thr Leu Trp Lys
            100                 105                 110

Gln Ala Glu Thr Lys Val Gln Ala Lys Ile Arg Lys Met Lys Val Thr
        115                 120                 125

Lys Lys Val Asn His His Tyr Lys Ile Asn Gly Lys Arg Lys Thr Ala
    130                 135                 140

Lys Glu Gln Lys Met Phe Gln Arg Ala Gln Glu Leu Arg Xaa Arg Ala
145                 150                 155                 160

Glu Asp Tyr Xaa Xaa Cys Lys Ile Thr Pro Ser Ala Arg Lys Pro Leu
                165                 170                 175

Cys Asn Xaa Val Arg Met Ala Ala Xaa Glu His Arg His Ser Ser Gly
            180                 185                 190

Leu Pro Tyr Trp Pro Tyr Leu Thr Ala Glu Thr Leu Lys Asn Arg Met
        195                 200                 205

Gly His Gln Pro Pro Pro Pro Thr Gln Gln His Ser Ile Ile Asp Asn
    210                 215                 220

Ser Leu Ser Leu Lys Thr Pro Ser Glu Cys Val Leu Tyr Pro Leu Ala
225                 230                 235                 240

Thr Leu Ser Gly 




<210> 2639
<211> 200
<212> PRT
<213> Homo sapiens

<400> 2639
Met Ala Leu Ala Leu Ala Ala Leu Ala Ala Val Glu Pro Ala Cys Gly
  1               5                  10                  15

Ser Arg Tyr Gln Gln Leu Gln Asn Glu Glu Glu Ser Gly Glu Pro Glu
             20                  25                  30

Gln Ala Ala Gly Asp Ala Pro Pro Pro Tyr Ser Ser Ile Ser Ala Glu
         35                  40                  45

Ser Ala Ala Tyr Phe Asp Tyr Lys Asp Glu Ser Gly Phe Pro Lys Pro
     50                  55                  60

Pro Ser Tyr Asn Val Ala Thr Thr Leu Pro Ser Tyr Asp Glu Ala Glu
 65                  70                  75                  80

Arg Thr Lys Ala Glu Ala Thr Ile Pro Leu Val Pro Gly Arg Asp Glu
                 85                  90                  95

Asp Phe Val Gly Arg Asp Asp Phe Asp Asp Ala Asp Gln Leu Arg Ile
            100                 105                 110

Gly Asn Asp Gly Ile Phe Met Leu Thr Phe Phe Met Ala Phe Leu Phe
        115                 120                 125

Asn Trp Ile Gly Phe Phe Leu Ser Phe Cys Leu Thr Thr Ser Ala Ala
    130                 135                 140

Gly Arg Tyr Gly Ala Ile Ser Gly Phe Gly Leu Ser Leu Ile Lys Trp
145                 150                 155                 160

Ile Leu Ile Val Arg Phe Ser Thr Tyr Phe Pro Ala Phe Met Asn Ser
                165                 170                 175

Leu Ser Arg Ser Lys Arg Thr Pro Ala Gly Ser Glu Ser Arg Cys Arg
            180                 185                 190

Thr Gln Arg Asn Asn His Leu Leu 
        195                 200



<210> 2640
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (15)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2640
Met Ile Thr Lys Asn Lys Asn Glu Ser Ser Lys Pro Asn Phe Xaa Phe
  1               5                  10                  15

Ser Pro Phe Ser Phe Phe Ser Gln Asp Val Pro Leu Ile Ser Leu Ala
             20                  25                  30

Asn Ile Leu His Asn Ala Lys Leu Trp Asn Asp Ala Val Ile Val Ala
         35                  40                  45

Thr Met Ala Val Glu Ile Ala Pro His Phe Ala Val Asn His Phe Thr
     50                  55                  60

Leu Gly Asn Val Tyr Val Ala Met Glu Glu Phe Glu Lys Ala Leu Val
 65                  70                  75                  80

Trp Tyr Glu Ser Thr Leu Lys Leu Gln Pro Glu Phe Val Pro Ala Lys
                 85                  90                  95

Asn Arg Ile Gln Thr Ile Gln Cys His Leu Met Leu Lys Lys Gly Arg
            100                 105                 110

Arg Ser Pro 
        115



<210> 2641
<211> 455
<212> PRT
<213> Homo sapiens

<400> 2641
Met Asp Arg Phe Thr Val Ala Gly Val Leu Pro Asp Ile Glu Gln Phe
  1               5                  10                  15

Phe Asn Ile Gly Asp Ser Ser Ser Gly Leu Ile Gln Thr Val Phe Ile
             20                  25                  30

Ser Ser Tyr Met Val Leu Ala Pro Val Phe Gly Tyr Leu Gly Asp Arg
         35                  40                  45

Tyr Asn Arg Lys Tyr Leu Met Cys Gly Gly Ile Ala Phe Trp Ser Leu
     50                  55                  60

Val Thr Leu Gly Ser Ser Phe Ile Pro Gly Glu His Phe Trp Leu Leu
 65                  70                  75                  80

Leu Leu Thr Arg Gly Leu Val Gly Val Gly Glu Ala Ser Tyr Ser Thr
                 85                  90                  95

Ile Ala Pro Thr Leu Ile Ala Asp Leu Phe Val Ala Asp Gln Arg Ser
            100                 105                 110

Arg Met Leu Ser Ile Phe Tyr Phe Ala Ile Pro Val Gly Ser Gly Leu
        115                 120                 125

Gly Tyr Ile Ala Gly Ser Lys Val Lys Asp Met Ala Gly Asp Trp His
    130                 135                 140

Trp Ala Leu Arg Val Thr Pro Gly Leu Gly Val Val Ala Val Leu Leu
145                 150                 155                 160

Leu Phe Leu Val Val Arg Glu Pro Pro Arg Gly Ala Val Glu Arg His
                165                 170                 175

Ser Asp Leu Pro Pro Leu Asn Pro Thr Ser Trp Trp Ala Asp Leu Arg
            180                 185                 190

Ala Leu Ala Arg Asn Pro Ser Phe Val Leu Ser Ser Leu Gly Phe Thr
        195                 200                 205

Ala Val Ala Phe Val Thr Gly Ser Leu Ala Leu Trp Ala Pro Ala Phe
    210                 215                 220

Leu Leu Arg Ser Arg Val Val Leu Gly Glu Thr Pro Pro Cys Leu Pro
225                 230                 235                 240

Gly Asp Ser Cys Ser Ser Ser Asp Ser Leu Ile Phe Gly Leu Ile Thr
                245                 250                 255

Cys Leu Thr Gly Val Leu Gly Val Gly Leu Gly Val Glu Ile Ser Arg
            260                 265                 270

Arg Leu Arg His Ser Asn Pro Arg Ala Asp Pro Leu Val Cys Ala Thr
        275                 280                 285

Gly Leu Leu Gly Ser Ala Pro Phe Leu Phe Leu Ser Leu Ala Cys Ala
    290                 295                 300

Arg Gly Ser Ile Val Ala Thr Tyr Ile Phe Ile Phe Ile Gly Glu Thr
305                 310                 315                 320

Leu Leu Ser Met Asn Trp Ala Ile Val Ala Asp Ile Leu Leu Tyr Val
                325                 330                 335

Val Ile Pro Thr Arg Arg Ser Thr Ala Glu Ala Phe Gln Ile Val Leu
            340                 345                 350

Ser His Leu Leu Gly Asp Ala Gly Ser Pro Tyr Leu Ile Gly Leu Ile
        355                 360                 365

Ser Asp Arg Leu Arg Arg Asn Trp Pro Pro Ser Phe Leu Ser Glu Phe
    370                 375                 380

Arg Ala Leu Gln Phe Ser Leu Met Leu Cys Ala Phe Val Gly Ala Leu
385                 390                 395                 400

Gly Gly Ala Ala Phe Leu Gly Thr Ala Ile Phe Ile Glu Ala Asp Arg
                405                 410                 415

Arg Arg Ala Gln Leu His Val Gln Gly Leu Leu His Glu Ala Gly Ser
            420                 425                 430

Thr Asp Asp Arg Ile Val Val Pro Gln Arg Gly Arg Ser Thr Arg Val
        435                 440                 445

Pro Val Ala Ser Val Leu Ile 
    450                 455



<210> 2642
<211> 295
<212> PRT
<213> Homo sapiens

<400> 2642
Met Thr Ile Ile Ile Ser Val Ile Val Ala Ile Ala Leu Ala Ile Gly
  1               5                  10                  15

Tyr Leu Ala Val Ala Lys Glu Lys Trp Thr Ser Thr Ala Ile Ile Thr
             20                  25                  30

Gln Pro Asp Val Gly Gln Ile Ala Gly Tyr Asn Asn Ala Met Asn Val
         35                  40                  45

Ile Tyr Gly Gln Ala Ala Pro Lys Val Ser Asp Leu Gln Glu Thr Leu
     50                  55                  60

Ile Gly Arg Phe Ser Ser Ala Phe Ser Ala Leu Ala Glu Thr Leu Asp
 65                  70                  75                  80

Asn Gln Glu Glu Arg Glu Lys Leu Thr Ile Glu Pro Ser Val Lys Asn
                 85                  90                  95

Gln Gln Leu Pro Leu Thr Val Ser Tyr Val Gly Gln Thr Ala Glu Gly
            100                 105                 110

Ala Gln Met Lys Leu Ala Gln Tyr Ile Gln Gln Val Asp Asp Lys Val
        115                 120                 125

Asn Gln Glu Leu Glu Lys Asp Leu Lys Asp Asn Ile Ala Leu Gly Arg
    130                 135                 140

Lys Asn Leu Gln Asp Ser Leu Arg Thr Gln Glu Val Val Ala Gln Glu
145                 150                 155                 160

Gln Lys Asp Leu Arg Ile Arg Gln Ile Gln Glu Ala Leu Gln Tyr Ala
                165                 170                 175

Asn Gln Ala Gln Val Thr Lys Pro Gln Ile Gln Gln Thr Gly Glu Asp
            180                 185                 190

Ile Thr Gln Asp Thr Leu Phe Leu Leu Gly Ser Glu Ala Leu Glu Ser
        195                 200                 205

Met Ile Lys His Glu Ala Thr Arg Pro Leu Val Phe Ser Pro Asn Tyr
    210                 215                 220

Tyr Gln Thr Arg Gln Asn Leu Leu Asp Ile Glu Ser Leu Lys Val Asp
225                 230                 235                 240

Asp Leu Asp Ile His Ala Tyr Arg Tyr Val Met Lys Pro Met Leu Pro
                245                 250                 255

Ile Arg Arg Asp Ser Pro Lys Lys Ala Ile Thr Leu Ile Leu Ala Val
            260                 265                 270

Leu Leu Gly Gly Met Val Gly Ala Gly Ile Val Leu Gly Arg Asn Ala
        275                 280                 285

Leu Arg Asn Tyr Asn Ala Lys 
    290                 295



<210> 2643
<211> 194
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (13)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (29)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (190)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2643
Met Gln Asp Ala Pro Leu Ser Cys Leu Ser Pro Thr Xaa Trp Ser Ser
  1               5                  10                  15

Val Ser Ser Ala Asp Ser Thr Glu Lys Ser Ala Ser Xaa Ala Gly Thr
             20                  25                  30

Arg Asn Leu Pro Phe Gln Phe Cys Leu Arg Gln Ala Leu Arg Met Lys
         35                  40                  45

Ala Ala Gly Ile Leu Thr Leu Ile Gly Cys Leu Val Thr Gly Ala Glu
     50                  55                  60

Ser Lys Ile Tyr Thr Arg Cys Lys Leu Ala Lys Ile Phe Ser Arg Ala
 65                  70                  75                  80

Gly Leu Asp Asn Tyr Trp Gly Phe Ser Leu Gly Asn Trp Ile Cys Met
                 85                  90                  95

Ala Tyr Tyr Glu Ser Gly Tyr Asn Thr Thr Ala Gln Thr Val Leu Asp
            100                 105                 110

Asp Gly Ser Ile Asp Tyr Gly Ile Phe Gln Ile Asn Ser Phe Ala Trp
        115                 120                 125

Cys Arg Arg Gly Lys Leu Lys Glu Asn Asn His Cys His Val Ala Cys
    130                 135                 140

Ser Ala Leu Val Thr Asp Asp Leu Thr Asp Ala Ile Ile Cys Ala Xaa
145                 150                 155                 160

Lys Ile Val Lys Glu Thr Gln Gly Met Asn Tyr Trp Gln Gly Trp Lys
                165                 170                 175

Lys His Cys Glu Gly Arg Asp Leu Ser Xaa Trp Lys Lys Xaa Cys Glu
            180                 185                 190

Val Ser 




<210> 2644
<211> 194
<212> PRT
<213> Homo sapiens

<400> 2644
Met Gln Leu Lys Lys Glu Ile Ser Leu Leu Asn Gly Val Ser Leu Val
  1               5                  10                  15

Val Gly Asn Met Ile Gly Ser Gly Ile Phe Val Ser Pro Lys Gly Val
             20                  25                  30

Leu Val His Thr Ala Ser Tyr Gly Met Ser Leu Ile Val Trp Ala Ile
         35                  40                  45

Gly Gly Leu Phe Ser Val Val Gly Ala Leu Cys Tyr Ala Glu Leu Gly
     50                  55                  60

Thr Thr Ile Thr Lys Ser Gly Ala Ser Tyr Ala Tyr Ile Leu Glu Ala
 65                  70                  75                  80

Phe Gly Gly Phe Ile Ala Phe Ile Arg Leu Trp Val Ser Leu Leu Val
                 85                  90                  95

Val Glu Pro Thr Gly Gln Ala Ile Ile Ala Ile Thr Phe Ala Asn Tyr
            100                 105                 110

Ile Ile Gln Pro Ser Phe Pro Ser Cys Asp Pro Pro Tyr Leu Ala Cys
        115                 120                 125

Arg Leu Leu Ala Ala Ala Cys Ile Cys Leu Leu Thr Phe Val Asn Cys
    130                 135                 140

Ala Tyr Val Lys Trp Gly Thr Arg Val Gln Asp Thr Phe Thr Tyr Ala
145                 150                 155                 160

Lys Val Val Ala Leu Ile Ala Ile Ile Val Met Gly Leu Val Lys Leu
                165                 170                 175

Cys Gln Gly Lys Trp Trp Glu Gly Gly Tyr His Gln Gln Phe Leu Trp
            180                 185                 190

Ile Pro 




<210> 2645
<211> 239
<212> PRT
<213> Homo sapiens

<400> 2645
Met Ala Tyr Gln Ser Leu Arg Leu Glu Tyr Leu Gln Ile Pro Pro Val
  1               5                  10                  15

Ser Arg Ala Tyr Thr Thr Ala Cys Val Leu Thr Thr Ala Ala Val Gln
             20                  25                  30

Leu Glu Leu Ile Thr Pro Phe Gln Leu Tyr Phe Asn Pro Glu Leu Ile
         35                  40                  45

Phe Lys His Phe Gln Ile Trp Arg Leu Ile Thr Asn Phe Leu Phe Phe
     50                  55                  60

Gly Pro Val Gly Phe Asn Phe Leu Phe Asn Met Ile Phe Leu Tyr Arg
 65                  70                  75                  80

Tyr Cys Arg Met Leu Glu Glu Gly Ser Phe Arg Gly Arg Thr Ala Asp
                 85                  90                  95

Phe Val Phe Met Phe Leu Phe Gly Gly Phe Leu Met Thr Leu Phe Gly
            100                 105                 110

Leu Phe Val Ser Leu Val Phe Leu Gly Gln Ala Phe Thr Ile Met Leu
        115                 120                 125

Val Tyr Val Trp Ser Arg Arg Asn Pro Tyr Val Arg Met Asn Phe Phe
    130                 135                 140

Gly Leu Leu Asn Phe Gln Ala Pro Phe Leu Pro Trp Val Leu Met Gly
145                 150                 155                 160

Phe Ser Leu Leu Leu Gly Asn Ser Ile Ile Val Asp Leu Leu Gly Ile
                165                 170                 175

Ala Val Gly His Ile Tyr Phe Phe Leu Glu Asp Val Phe Pro Asn Gln
            180                 185                 190

Pro Gly Gly Ile Arg Ile Leu Lys Thr Pro Ser Ile Leu Lys Ala Ile
        195                 200                 205

Phe Asp Thr Pro Asp Glu Asp Pro Asn Tyr Asn Pro Leu Pro Glu Glu
    210                 215                 220

Arg Pro Gly Gly Phe Ala Trp Gly Glu Gly Gln Arg Leu Gly Gly 
225                 230                 235



<210> 2646
<211> 202
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (93)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2646
Met Ala Ala Pro Trp Arg Arg Trp Pro Thr Gly Leu Leu Ala Val Leu
  1               5                  10                  15

Arg Pro Leu Leu Thr Cys Arg Pro Leu Gln Gly Thr Thr Leu Gln Arg
             20                  25                  30

Asp Val Leu Leu Phe Glu His Asp Arg Gly Arg Phe Phe Thr Ile Leu
         35                  40                  45

Gly Leu Phe Cys Ala Gly Gln Gly Val Phe Trp Ala Ser Met Ala Val
     50                  55                  60

Ala Ala Val Ser Arg Pro Pro Val Pro Val Gln Pro Leu Asp Ala Glu
 65                  70                  75                  80

Val Pro Asn Arg Gly Pro Phe Asp Leu Arg Ser Ala Xaa Trp Arg Tyr
                 85                  90                  95

Gly Leu Ala Val Gly Cys Gly Ala Ile Gly Ala Leu Val Leu Gly Ala
            100                 105                 110

Gly Leu Leu Phe Ser Leu Arg Ser Val Arg Ser Val Val Leu Arg Ala
        115                 120                 125

Gly Gly Gln Gln Val Thr Leu Thr Thr His Ala Pro Phe Gly Leu Gly
    130                 135                 140

Ala His Phe Thr Val Pro Leu Lys Gln Val Ser Cys Met Ala His Arg
145                 150                 155                 160

Gly Glu Val Pro Ala Met Leu Pro Leu Lys Val Lys Gly Arg Arg Phe
                165                 170                 175

Tyr Phe Leu Leu Asp Lys Thr Gly His Phe Pro Asn Thr Lys Leu Phe
            180                 185                 190

Asp Asn Thr Val Gly Ala Tyr Arg Ser Leu 
        195                 200



<210> 2647
<211> 307
<212> PRT
<213> Homo sapiens

<400> 2647
Met Lys Glu Asp Cys Leu Pro Ser Ser His Val Pro Ile Ser Asp Ser
  1               5                  10                  15

Lys Ser Ile Gln Lys Ser Glu Leu Leu Gly Leu Leu Lys Thr Tyr Asn
             20                  25                  30

Cys Tyr His Glu Gly Lys Ser Phe Gln Leu Arg His Arg Glu Glu Glu
         35                  40                  45

Gly Thr Leu Ile Ile Glu Gly Leu Leu Asn Ile Ala Trp Gly Leu Arg
     50                  55                  60

Arg Pro Ile Arg Leu Gln Met Gln Asp Asp Arg Glu Gln Val His Leu
 65                  70                  75                  80

Pro Ser Thr Ser Trp Met Pro Arg Arg Pro Ser Cys Pro Leu Gly Cys
                 85                  90                  95

Trp Ser Leu Leu Leu Gly Leu Ser Ser Leu Ser Leu Pro Ala Ala Ile
            100                 105                 110

Ser Ala Leu Gln Leu Ser Val Phe Arg Lys Glu Pro Ser Pro Gln Asn
        115                 120                 125

Gly Asn Ile Thr Ala Gln Gly Pro Ser Ile Gln Pro Val His Lys Ala
    130                 135                 140

Glu Ser Ser Thr Asp Ser Ser Gly Pro Leu Glu Glu Ala Glu Glu Ala
145                 150                 155                 160

Pro Gln Leu Met Arg Thr Lys Ser Asp Ala Ser Cys Met Ser Gln Arg
                165                 170                 175

Arg Pro Lys Cys Arg Ala Pro Gly Glu Ala Gln Arg Ile Arg Arg His
            180                 185                 190

Arg Phe Ser Ile Asn Gly His Phe Tyr Asn His Lys Thr Ser Val Phe
        195                 200                 205

Thr Pro Ala Tyr Gly Ser Val Thr Asn Val Arg Val Asn Ser Thr Met
    210                 215                 220

Thr Thr Leu Gln Val Leu Thr Leu Leu Leu Asn Lys Phe Arg Val Glu
225                 230                 235                 240

Asp Gly Pro Ser Glu Phe Ala Leu Tyr Ile Val His Glu Ser Gly Glu
                245                 250                 255

Arg Thr Lys Leu Lys Asp Cys Glu Tyr Pro Leu Ile Ser Arg Ile Leu
            260                 265                 270

His Gly Pro Cys Glu Lys Ile Ala Arg Ile Phe Leu Met Glu Ala Asp
        275                 280                 285

Leu Gly Val Glu Val Pro His Glu Val Ser Gly Gly Gln Gly Trp Gly
    290                 295                 300

Gly Leu Leu 
305



<210> 2648
<211> 193
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2648
Met Ile Arg Cys Gly Leu Ala Cys Glu Arg Cys Arg Trp Ile Leu Pro
  1               5                  10                  15

Leu Leu Leu Leu Ser Ala Ile Ala Phe Asp Ile Ile Ala Leu Ala Gly
             20                  25                  30

Arg Gly Trp Leu Gln Ser Ser Asp His Gly Gln Thr Ser Ser Leu Trp
         35                  40                  45

Trp Lys Cys Ser Gln Glu Gly Gly Gly Ser Gly Ser Tyr Glu Glu Gly
     50                  55                  60

Cys Gln Ser Leu Met Glu Tyr Ala Trp Gly Arg Ala Ala Ala Ala Met
 65                  70                  75                  80

Leu Phe Cys Gly Phe Ile Ile Leu Val Ile Cys Phe Ile Leu Ser Phe
                 85                  90                  95

Phe Ala Leu Cys Gly Pro Gln Met Leu Val Phe Leu Arg Val Ile Gly
            100                 105                 110

Gly Leu Leu Ala Leu Ala Ala Val Phe Gln Ile Ile Ser Leu Val Ile
        115                 120                 125

Tyr Pro Val Lys Tyr Thr Gln Thr Phe Thr Leu His Ala Asn Xaa Ala
    130                 135                 140

Val Thr Tyr Ile Tyr Asn Trp Ala Tyr Gly Phe Gly Trp Ala Ala Thr
145                 150                 155                 160

Ile Ile Leu Ile Gly Cys Ala Phe Phe Phe Cys Cys Leu Pro Asn Tyr
                165                 170                 175

Glu Asp Asp Leu Leu Gly Asn Ala Lys Pro Arg Tyr Phe Tyr Thr Ser
            180                 185                 190

Ala 




<210> 2649
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (68)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (70)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (73)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (80)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (89)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2649
Met Pro Gly Gln Glu Asp Glu Gly Ala Leu Trp Thr Gln Gln Ser Ala
  1               5                  10                  15

Glu Phe Arg Ser Gly Lys Pro Met Val Ala Gly Thr Pro Cys Phe Leu
             20                  25                  30

Pro Leu Leu Ser Ala Cys Val Thr His Ile Asn Gly Asn Asn Phe Phe
         35                  40                  45

Gln Leu Leu Ala Glu Val Gly Glu Ala Gly Ser Leu His Arg Glu Gly
     50                  55                  60

Leu Ser Leu Xaa Cys Xaa Pro Leu Xaa Ser Val Leu Ala Xaa Xaa Xaa
 65                  70                  75                  80

Gly Ser Ser Ile Leu Ser Phe Pro Xaa Leu Pro Leu Trp Thr Gly Val
                 85                  90                  95

Leu Pro Phe Gln Phe Leu Cys Phe Gly Val Phe Pro Tyr Leu Leu Thr
            100                 105                 110






<210> 2650
<211> 186
<212> PRT
<213> Homo sapiens

<400> 2650
Met Leu Val Met Asp Cys His Arg Thr His Leu Ser Glu Glu Val Leu
  1               5                  10                  15

Ala Met Leu Ser Ala Ser Ser Thr Leu Pro Ala Val Val Pro Ala Gly
             20                  25                  30

Cys Ser Ser Lys Ile Gln Pro Leu Asp Val Cys Ile Lys Arg Thr Val
         35                  40                  45

Lys Asn Phe Leu His Lys Lys Trp Lys Glu Gln Ala Arg Glu Met Ala
     50                  55                  60

Asp Thr Ala Cys Asp Ser Asp Val Leu Leu Gln Leu Val Leu Val Trp
 65                  70                  75                  80

Leu Gly Glu Val Leu Gly Val Ile Gly Asp Cys Pro Glu Leu Val Gln
                 85                  90                  95

Arg Ser Phe Leu Val Ala Ser Val Leu Pro Gly Pro Asp Gly Asn Ile
            100                 105                 110

Asn Ser Pro Thr Arg Asn Ala Asp Met Gln Glu Glu Leu Ile Ala Ser
        115                 120                 125

Leu Glu Glu Gln Leu Lys Leu Ser Gly Glu His Ser Glu Ser Ser Thr
    130                 135                 140

Pro Arg Pro Arg Ser Ser Pro Glu Glu Thr Ile Glu Pro Glu Ser Leu
145                 150                 155                 160

His Gln Leu Phe Glu Gly Glu Ser Glu Thr Glu Ser Phe Tyr Gly Phe
                165                 170                 175

Glu Glu Ala Asp Leu Asp Leu Met Glu Ile 
            180                 185



<210> 2651
<211> 300
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (234)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (252)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (263)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2651
Met Val Lys Thr Phe Glu Asp Arg Met Asp Leu Phe Ser Ala Leu Ile
  1               5                  10                  15

Lys Gly Pro Thr Arg Thr Pro Tyr Glu Asp Gly Leu Tyr Leu Phe Asp
             20                  25                  30

Ile Gln Leu Pro Asn Ile Tyr Pro Ala Val Pro Pro His Phe Cys Tyr
         35                  40                  45

Leu Ser Gln Cys Ser Gly Arg Leu Asn Pro Asn Leu Tyr Asp Asn Gly
     50                  55                  60

Lys Val Cys Val Ser Leu Leu Gly Thr Trp Ile Gly Lys Gly Thr Glu
 65                  70                  75                  80

Arg Trp Thr Ser Lys Ser Ser Leu Leu Gln Val Leu Ile Ser Ile Gln
                 85                  90                  95

Gly Leu Ile Leu Val Asn Glu Pro Tyr Tyr Asn Glu Ala Gly Phe Asp
            100                 105                 110

Ser Asp Arg Gly Leu Gln Glu Gly Tyr Glu Asn Ser Arg Cys Tyr Asn
        115                 120                 125

Glu Met Ala Leu Ile Arg Val Val Gln Ser Met Thr Gln Leu Val Arg
    130                 135                 140

Arg Pro Pro Glu Val Phe Glu Gln Glu Ile Arg Gln His Phe Ser Thr
145                 150                 155                 160

Gly Gly Trp Arg Leu Val Asn Arg Ile Glu Ser Trp Leu Glu Thr His
                165                 170                 175

Ala Leu Leu Glu Lys Ala Gln Ala Leu Pro Asn Gly Val Pro Lys Ala
            180                 185                 190

Ser Ser Ser Pro Glu Pro Pro Ala Val Ala Glu Leu Ser Asp Ser Gly
        195                 200                 205

Gln Gln Glu Pro Glu Asp Gly Gly Pro Ala Pro Gly Glu Ala Ser Gln
    210                 215                 220

Gly Ser Asp Ser Glu Gly Gly Ala Gln Xaa Leu Ala Ser Ala Ser Arg
225                 230                 235                 240

Asp His Thr Asp Gln Thr Ser Glu Thr Ala Pro Xaa Ala Ser Val Pro
                245                 250                 255

Pro Ser Val Lys Pro Lys Xaa Arg Arg Lys Glu Ala Thr Gly Ala Ser
            260                 265                 270

Tyr Leu Arg Arg Xaa Ala Thr Leu Thr Ser Ala Ser Pro Ser Ser His
        275                 280                 285

Phe Pro Arg Val Ser Ser Arg Ala Ser Gly Val Ser 
    290                 295                 300



<210> 2652
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (149)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2652
Met Phe Pro Gln Cys Lys Phe Ser Arg Glu Phe Leu His Pro Arg Tyr
  1               5                  10                  15

Trp Leu Thr Trp Phe Gly Leu Gly Val Leu Trp Leu Trp Val Gln Leu
             20                  25                  30

Pro Tyr Pro Val Leu Cys Phe Leu Gly Thr Arg Ile Gly Ala Met Ala
         35                  40                  45

Arg Pro Phe Leu Lys Arg Arg Glu Ser Ile Ala Arg Lys Asn Leu Glu
     50                  55                  60

Leu Cys Phe Pro Gln His Ser Ala Glu Glu Arg Glu Lys Met Ile Ala
 65                  70                  75                  80

Glu Asn Phe Arg Ser Leu Gly Met Ala Leu Val Glu Thr Gly Met Ala
                 85                  90                  95

Trp Phe Trp Pro Asp Ser Arg Val Arg Lys Trp Phe Asp Val Glu Gly
            100                 105                 110

Leu Asp Asn Leu Lys Arg Ala Gln Met Gln Asn Arg Gly Val Met Val
        115                 120                 125

Val Gly Val His Phe Met Ser Leu Glu Leu Gly Gly Ala Leu Lys Asp
    130                 135                 140

Pro Pro Arg Ala Xaa Leu Thr Xaa His Arg Arg Pro 
145                 150                 155



<210> 2653
<211> 237
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (36)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2653
Met Thr Ser Glu Ile Thr Tyr Ala Glu Val Arg Phe Lys Asn Glu Phe
  1               5                  10                  15

Lys Ser Ser Gly Ile Asn Thr Ala Ser Ser Ala Ala Ser Lys Glu Arg
             20                  25                  30

Thr Ala Pro Xaa Lys Ser Asn Thr Gly Phe Pro Lys Leu Leu Cys Ala
         35                  40                  45

Ser Leu Leu Ile Phe Phe Leu Leu Leu Ala Ile Ser Phe Phe Ile Ala
     50                  55                  60

Phe Val Ile Phe Phe Gln Lys Tyr Ser Gln Leu Leu Glu Lys Lys Thr
 65                  70                  75                  80

Thr Lys Glu Leu Val His Thr Thr Leu Glu Cys Val Lys Lys Asn Met
                 85                  90                  95

Pro Val Glu Glu Thr Ala Trp Ser Cys Cys Pro Lys Asn Trp Lys Ser
            100                 105                 110

Phe Ser Ser Asn Cys Tyr Phe Ile Ser Thr Glu Ser Ala Ser Trp Gln
        115                 120                 125

Asp Ser Glu Lys Asp Cys Ala Arg Met Glu Ala His Leu Leu Val Ile
    130                 135                 140

Asn Thr Gln Glu Glu Gln Asp Phe Ile Phe Gln Asn Leu Gln Glu Glu
145                 150                 155                 160

Ser Ala Tyr Phe Val Gly Leu Ser Asp Pro Glu Gly Gln Arg His Trp
                165                 170                 175

Gln Trp Val Asp Gln Thr Pro Tyr Asn Glu Ser Ser Thr Phe Trp His
            180                 185                 190

Pro Arg Glu Pro Ser Asp Pro Asn Glu Arg Cys Val Val Leu Asn Phe
        195                 200                 205

Arg Lys Ser Pro Lys Arg Trp Gly Trp Asn Asp Val Asn Cys Leu Gly
    210                 215                 220

Pro Gln Arg Ser Val Cys Glu Met Met Lys Ile His Leu 
225                 230                 235



<210> 2654
<211> 363
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (10)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2654
Met Asp Ile Leu Thr Leu Ala His Thr Xaa Thr Glu Ala Lys Gly Leu
  1               5                  10                  15

Ser Ser Glu Ser Ser Ala Ser Ser Asp Gly Pro His Pro Val Ile Thr
             20                  25                  30

Pro Ser Arg Ala Ser Glu Ser Ser Ala Ser Ser Asp Gly Pro His Pro
         35                  40                  45

Val Ile Thr Pro Ser Trp Ser Pro Gly Ser Asp Val Thr Leu Leu Ala
     50                  55                  60

Glu Ala Leu Val Thr Val Thr Asn Ile Glu Val Ile Asn Cys Ser Ile
 65                  70                  75                  80

Thr Glu Ile Glu Thr Thr Thr Ser Ser Ile Pro Gly Ala Ser Asp Ile
                 85                  90                  95

Asp Leu Ile Pro Thr Glu Gly Val Lys Ala Ser Ser Thr Ser Asp Pro
            100                 105                 110

Pro Ala Leu Pro Asp Ser Thr Glu Ala Lys Pro His Ile Thr Glu Val
        115                 120                 125

Thr Ala Ser Ala Glu Thr Leu Ser Thr Ala Gly Thr Thr Glu Ser Ala
    130                 135                 140

Ala Pro His Ala Thr Val Gly Thr Pro Leu Pro Thr Asn Ser Xaa Xaa
145                 150                 155                 160

Glu Arg Glu Val Thr Ala Pro Xaa Ala Thr Thr Leu Ser Gly Ala Leu
                165                 170                 175

Val Thr Val Ser Arg Asn Pro Leu Glu Glu Thr Ser Ala Leu Ser Val
            180                 185                 190

Glu Thr Pro Ser Tyr Val Lys Val Ser Gly Ala Ala Pro Val Ser Ile
        195                 200                 205

Glu Ala Gly Ser Ala Val Gly Lys Thr Thr Ser Phe Ala Gly Ser Ser
    210                 215                 220

Ala Ser Ser Tyr Ser Pro Ser Glu Ala Ala Leu Lys Asn Phe Thr Pro
225                 230                 235                 240

Ser Glu Thr Pro Thr Met Asp Ile Ala Thr Lys Gly Pro Phe Pro Thr
                245                 250                 255

Ser Arg Asp Pro Leu Pro Ser Val Pro Pro Thr Thr Thr Asn Ser Ser
            260                 265                 270

Arg Gly Thr Asn Ser Thr Leu Ala Lys Ile Thr Thr Ser Ala Lys Thr
        275                 280                 285

Thr Met Lys Pro Pro Thr Ala Thr Pro Thr Thr Ala Arg Thr Arg Pro
    290                 295                 300

Thr Thr Asp Val Ser Ala Gly Glu Asn Gly Gly Phe Leu Leu Leu Arg
305                 310                 315                 320

Leu Ser Val Ala Ser Pro Glu Asp Leu Thr Asp Pro Arg Val Ala Glu
                325                 330                 335

Arg Leu Met Gln Gln Leu His Arg Glu Leu His Ala His Ala Pro His
            340                 345                 350

Phe Gln Val Ser Leu Leu Arg Val Arg Arg Gly 
        355                 360



<210> 2655
<211> 148
<212> PRT
<213> Homo sapiens

<400> 2655
Met His Cys Pro Thr Val Pro Asp Glu Lys Asn His Tyr Glu Lys Ser
  1               5                  10                  15

Ser Gly Ser Ser Glu Gly Gln Ser Lys Thr Glu Ser Asp Phe Ser Asn
             20                  25                  30

Leu Asp Ser Glu Lys His Lys Lys Gly Pro Met Glu Thr Gly Leu Phe
         35                  40                  45

Pro Gly Ser Asn Ala Thr Phe Arg Ile Leu Glu Val Gly Cys Gly Ala
     50                  55                  60

Gly Asn Ser Val Phe Pro Ile Leu Asn Thr Leu Glu Asn Ser Pro Glu
 65                  70                  75                  80

Ser Phe Leu Tyr Cys Cys Asp Phe Ala Ser Gly Ala Val Glu Leu Val
                 85                  90                  95

Lys Ser His Ser Ser Tyr Arg Ala Thr Gln Cys Phe Ala Phe Val His
            100                 105                 110

Asp Val Cys Asp Asp Gly Leu Pro Tyr Pro Phe Pro Asp Gly Ile Leu
        115                 120                 125

Asp Val Ile Leu Leu Val Phe Val Leu Ser Ser Ile His Pro Asp Arg
    130                 135                 140

Thr Leu Phe Ile 
145



<210> 2656
<211> 230
<212> PRT
<213> Homo sapiens

<400> 2656
Met Glu Pro Leu Arg Leu Leu Ile Leu Leu Phe Val Thr Glu Leu Ser
  1               5                  10                  15

Gly Ala His Asn Thr Thr Val Phe Gln Gly Val Ala Gly Gln Ser Leu
             20                  25                  30

Gln Val Ser Cys Pro Tyr Asp Ser Met Lys His Trp Gly Arg Arg Lys
         35                  40                  45

Ala Trp Cys Arg Gln Leu Gly Glu Lys Gly Pro Cys Gln Arg Val Val
     50                  55                  60

Ser Thr His Asn Leu Trp Leu Leu Ser Phe Leu Arg Arg Trp Asn Gly
 65                  70                  75                  80

Ser Thr Ala Ile Thr Asp Asp Thr Leu Gly Gly Thr Leu Thr Ile Thr
                 85                  90                  95

Leu Arg Asn Leu Gln Pro His Asp Ala Gly Leu Tyr Gln Cys Gln Ser
            100                 105                 110

Leu His Gly Ser Glu Ala Asp Thr Leu Arg Lys Val Leu Val Glu Val
        115                 120                 125

Leu Ala Asp Pro Leu Asp His Arg Asp Ala Gly Asp Leu Trp Phe Pro
    130                 135                 140

Gly Glu Ser Glu Ser Phe Glu Asp Ala His Val Glu His Ser Ile Ser
145                 150                 155                 160

Arg Ser Leu Leu Glu Gly Glu Ile Pro Phe Pro Pro Thr Ser Ile Leu
                165                 170                 175

Leu Leu Leu Ala Cys Ile Phe Leu Ile Lys Ile Leu Ala Ala Ser Ala
            180                 185                 190

Leu Trp Ala Ala Ala Trp His Gly Gln Lys Pro Gly Thr His Pro Pro
        195                 200                 205

Ser Glu Leu Asp Cys Gly His Asp Pro Gly Tyr Gln Leu Gln Thr Leu
    210                 215                 220

Pro Gly Leu Arg Asp Thr 
225                 230



<210> 2657
<211> 240
<212> PRT
<213> Homo sapiens

<400> 2657
Met Gly Asn Cys Gln Ala Gly His Asn Leu His Leu Cys Leu Ala His
  1               5                  10                  15

His Pro Pro Leu Val Cys Ala Thr Leu Ile Leu Leu Leu Leu Gly Leu
             20                  25                  30

Ser Gly Leu Gly Leu Gly Ser Phe Leu Leu Thr His Arg Thr Gly Leu
         35                  40                  45

Arg Ser Pro Asp Ile Pro Gln Asp Trp Val Ser Phe Leu Arg Ser Phe
     50                  55                  60

Gly Gln Leu Thr Leu Cys Pro Arg Asn Gly Thr Val Thr Gly Lys Trp
 65                  70                  75                  80

Arg Gly Ser His Val Val Gly Leu Leu Thr Thr Leu Asn Phe Gly Asp
                 85                  90                  95

Gly Pro Asp Arg Asn Lys Thr Arg Thr Phe Gln Ala Thr Val Leu Gly
            100                 105                 110

Ser Gln Met Gly Leu Lys Gly Ser Ser Ala Gly Gln Leu Val Leu Ile
        115                 120                 125

Thr Ala Arg Val Thr Thr Glu Arg Thr Ala Gly Thr Cys Leu Tyr Phe
    130                 135                 140

Ser Ala Val Pro Gly Ile Leu Pro Ser Ser Gln Pro Pro Ile Ser Cys
145                 150                 155                 160

Ser Glu Glu Gly Ala Gly Asn Ala Thr Leu Ser Pro Arg Met Gly Glu
                165                 170                 175

Glu Cys Val Ser Val Trp Ser His Glu Gly Leu Val Leu Thr Lys Leu
            180                 185                 190

Leu Thr Ser Glu Glu Leu Ala Leu Cys Gly Ser Arg Leu Leu Val Leu
        195                 200                 205

Gly Ser Phe Leu Leu Leu Phe Cys Gly Leu Leu Cys Cys Val Thr Ala
    210                 215                 220

Met Cys Phe His Pro Arg Arg Glu Ser His Trp Ser Arg Thr Arg Leu
225                 230                 235                 240






<210> 2658
<211> 271
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2658
Met Ala Ser Ala Asp Ser Arg Arg Xaa Ala Asp Gly Gly Gly Ala Gly
  1               5                  10                  15

Gly Thr Phe Gln Pro Tyr Leu Asp Thr Leu Arg Gln Glu Leu Gln Gln
             20                  25                  30

Thr Asp Pro Thr Leu Leu Ser Val Val Val Ala Val Leu Ala Val Leu
         35                  40                  45

Leu Thr Leu Val Phe Trp Lys Leu Ile Arg Ser Arg Arg Ser Ser Gln
     50                  55                  60

Arg Ala Val Leu Leu Val Gly Leu Cys Asp Ser Gly Lys Thr Leu Leu
 65                  70                  75                  80

Phe Val Arg Leu Leu Thr Gly Leu Tyr Arg Asp Thr Gln Thr Ser Ile
                 85                  90                  95

Thr Asp Ser Cys Ala Val Tyr Arg Val Asn Asn Asn Arg Gly Asn Ser
            100                 105                 110

Leu Thr Leu Ile Asp Leu Pro Gly His Glu Ser Leu Arg Leu Gln Phe
        115                 120                 125

Leu Glu Arg Phe Lys Ser Ser Ala Arg Ala Ile Val Phe Val Val Asp
    130                 135                 140

Ser Ala Ala Phe Gln Arg Glu Val Lys Asp Val Ala Glu Phe Leu Tyr
145                 150                 155                 160

Gln Val Leu Ile Asp Ser Met Gly Leu Lys Asn Thr Pro Ser Phe Leu
                165                 170                 175

Ile Ala Cys Asn Lys Gln Asp Ile Ala Met Ala Lys Ser Ala Lys Leu
            180                 185                 190

Ile Gln Gln Gln Leu Glu Lys Glu Leu Asn Thr Leu Arg Val Thr Arg
        195                 200                 205

Ser Ala Ala Pro Ser Thr Leu Asp Ser Ser Ser Thr Ala Pro Ala Gln
    210                 215                 220

Leu Gly Lys Lys Gly Lys Glu Phe Glu Phe Ser Gln Leu Pro Leu Lys
225                 230                 235                 240

Val Glu Phe Leu Glu Cys Ser Ala Lys Gly Gly Arg Gly Asp Val Gly
                245                 250                 255

Ser Ala Asp Ile Gln Asp Leu Glu Lys Trp Leu Ala Lys Ile Ala 
            260                 265                 270



<210> 2659
<211> 196
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (160)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (179)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (184)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (193)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2659
Met Gly Phe Asn Leu Thr Leu Ala Lys Leu Pro Asn Asn Glu Leu His
  1               5                  10                  15

Gly Gln Glu Ser His Asn Ser Gly Asn Arg Ser Asp Gly Pro Gly Lys
             20                  25                  30

Asn Thr Thr Leu His Asn Glu Phe Asp Thr Ile Val Leu Pro Val Leu
         35                  40                  45

Tyr Leu Ile Ile Phe Val Ala Ser Ile Leu Leu Asn Gly Leu Ala Val
     50                  55                  60

Trp Ile Phe Phe His Ile Arg Asn Lys Thr Ser Phe Ile Phe Tyr Leu
 65                  70                  75                  80

Lys Asn Ile Val Val Ala Asp Leu Ile Met Thr Leu Thr Phe Pro Phe
                 85                  90                  95

Arg Ile Val His Asp Ala Gly Phe Gly Pro Trp Tyr Phe Lys Phe Ile
            100                 105                 110

Leu Cys Arg Tyr Thr Ser Val Leu Phe Tyr Ala Asn Met Tyr Thr Ser
        115                 120                 125

Ile Val Phe Leu Gly Leu Ile Ser Ile Asp Arg Tyr Leu Lys Val Val
    130                 135                 140

Lys Pro Phe Gly Asp Ser Arg Met Tyr Ser Ile Thr Phe Thr Lys Xaa
145                 150                 155                 160

Leu Ser Val Cys Val Trp Val Ile Met Ala Gly Leu Leu Xaa Gln Thr
                165                 170                 175

Xaa Xaa Xaa Gln Met Val Lys Xaa Thr Xaa Gly Gln Ile Phe Leu Asn
            180                 185                 190

Xaa Phe Lys Thr 
        195



<210> 2660
<211> 133
<212> PRT
<213> Homo sapiens

<400> 2660
Met Trp Pro Gln Phe Arg Thr Ile Gln Glu Lys Glu Val Ile Ile Leu
  1               5                  10                  15

Asn Asn Lys Glu Cys Asp Asn Phe Tyr His Asn Phe Thr Lys Ile Pro
             20                  25                  30

Thr Leu Val Gln Ile Ile Lys Ser Gln Met Met Cys Ala Glu Asp Thr
         35                  40                  45

His Arg Glu Lys Phe Cys Tyr Glu Leu Thr Gly Glu Pro Leu Val Cys
     50                  55                  60

Ser Met Glu Gly Thr Trp Tyr Leu Val Gly Leu Val Ser Trp Gly Ala
 65                  70                  75                  80

Gly Cys Gln Lys Ser Glu Ala Pro Pro Ile Tyr Leu Gln Val Ser Ser
                 85                  90                  95

Tyr Gln His Trp Ile Trp Asp Cys Leu Asn Gly Gln Ala Leu Ala Leu
            100                 105                 110

Pro Ala Pro Ser Arg Thr Leu Leu Leu Ala Leu Pro Leu Pro Leu Ser
        115                 120                 125

Leu Leu Ala Ala Leu 
    130



<210> 2661
<211> 307
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (42)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (165)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (244)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (247)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (297)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2661
Met Gly Thr Gln Glu Gly Trp Cys Leu Leu Leu Cys Leu Ala Leu Ser
  1               5                  10                  15

Gly Ala Ala Glu Thr Lys Pro His Pro Ala Glu Gly Gln Trp Arg Ala
             20                  25                  30

Val Asp Val Val Leu Asp Cys Phe Leu Xaa Lys Asp Gly Ala His Arg
         35                  40                  45

Gly Ala Leu Ala Ser Ser Glu Asp Arg Ala Arg Ala Ser Leu Val Leu
     50                  55                  60

Lys Gln Val Pro Val Leu Asp Asp Gly Ser Leu Glu Asp Phe Thr Asp
 65                  70                  75                  80

Phe Gln Gly Gly Thr Leu Ala Gln Asp Asp Pro Pro Ile Ile Phe Glu
                 85                  90                  95

Ala Ser Val Asp Leu Val Gln Ile Pro Gln Ala Glu Ala Leu Leu His
            100                 105                 110

Ala Asp Cys Ser Gly Lys Glu Val Thr Cys Glu Ile Ser Arg Tyr Phe
        115                 120                 125

Leu Gln Met Thr Glu Thr Thr Val Lys Thr Ala Ala Trp Phe Met Ala
    130                 135                 140

Asn Met Gln Val Ser Gly Gly Gly Pro Ser Ile Ser Leu Val Met Lys
145                 150                 155                 160

Thr Pro Arg Val Xaa Lys Asn Glu Ala Leu Trp His Pro Thr Leu Asn
                165                 170                 175

Leu Pro Leu Ser Pro Gln Gly Thr Val Arg Thr Ala Val Glu Phe Gln
            180                 185                 190

Val Met Thr Gln Thr Gln Ser Leu Ser Phe Leu Leu Gly Ser Ser Ala
        195                 200                 205

Ser Leu Asp Cys Gly Phe Ser Met Ala Pro Gly Leu Asp Leu Ile Ser
    210                 215                 220

Val Glu Trp Arg Leu Gln His Lys Gly Arg Gly Gln Leu Val Tyr Ser
225                 230                 235                 240

Trp Thr Ala Xaa Gln Gly Xaa Ala Val Arg Lys Gly Ala Thr Trp Thr
                245                 250                 255

Cys Thr Thr Gly His Gly Arg Met Leu Leu Thr Cys Arg Leu Ile Tyr
            260                 265                 270

Arg Gln Gly Leu Leu Ala Ile His Ser Leu Arg Leu Thr Ile Ser Leu
        275                 280                 285

Thr Pro Leu Leu Ile Ile Leu Glu Xaa Phe Ser Pro Ser Gln Cys Val
    290                 295                 300

Tyr Leu Met 
305



<210> 2662
<211> 122
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2662
Met Thr Met Ile Thr Pro Ser Ser Lys Leu Xaa Leu Thr Lys Gly Xaa
  1               5                  10                  15

Lys Ser Trp Ser Ser Thr Ala Val Ala Ala Ala Leu Glu Leu Val Asp
             20                  25                  30

Pro Pro Gly Cys Arg Asn Ser Ala Arg Asp Gln Asp Phe Phe Phe Ile
         35                  40                  45

Thr Gln Pro Met Thr Met Tyr Ile Glu Val Ser Leu Arg Thr Lys Asp
     50                  55                  60

Val His Thr Cys Phe Lys Val Val Leu Val Met Ile Ile Arg Ile Ile
 65                  70                  75                  80

Arg Gly Thr Lys Tyr Gln Met Gln Glu Asn Gly Pro Glu Cys Gln Tyr
                 85                  90                  95

Asn Gln Asn Lys Lys Cys Ile Asn Ser Asp Leu Leu Glu Ala Glu Ile
            100                 105                 110

Asn Ser Phe Leu Asp Ala Phe Leu Val Phe 
        115                 120



<210> 2663
<211> 201
<212> PRT
<213> Homo sapiens

<400> 2663
Met Ala Arg Ile Glu Ser Tyr Glu Gly Arg Glu Lys Lys Gly Ile Ser
  1               5                  10                  15

Asp Val Arg Arg Thr Phe Cys Leu Phe Val Thr Phe Asp Leu Leu Phe
             20                  25                  30

Val Thr Leu Leu Trp Ile Ile Glu Leu Asn Val Asn Gly Gly Ile Glu
         35                  40                  45

Asn Thr Leu Glu Lys Glu Val Met Gln Tyr Asp Tyr Tyr Ser Ser Tyr
     50                  55                  60

Phe Asp Ile Phe Leu Leu Ala Val Phe Arg Phe Lys Val Leu Ile Leu
 65                  70                  75                  80

Ala Tyr Ala Val Cys Arg Leu Arg His Trp Trp Ala Ile Ala Leu Thr
                 85                  90                  95

Thr Ala Val Thr Ser Ala Phe Leu Leu Ala Lys Val Ile Leu Ser Lys
            100                 105                 110

Leu Phe Ser Gln Gly Ala Phe Gly Tyr Val Leu Pro Ile Ile Ser Phe
        115                 120                 125

Ile Leu Ala Trp Ile Glu Thr Trp Phe Leu Asp Phe Lys Val Leu Pro
    130                 135                 140

Gln Glu Ala Glu Glu Glu Asn Arg Leu Leu Ile Val Gln Asp Ala Ser
145                 150                 155                 160

Glu Arg Ala Ala Leu Ile Pro Gly Gly Leu Ser Asp Gly Gln Phe Tyr
                165                 170                 175

Ser Pro Pro Glu Ser Glu Ala Gly Ser Glu Glu Ala Glu Glu Lys Gln
            180                 185                 190

Asp Ser Glu Lys Pro Leu Leu Glu Leu 
        195                 200



<210> 2664
<211> 273
<212> PRT
<213> Homo sapiens

<400> 2664
Met Leu Phe Phe Cys Gly Asp Leu Leu Ser Arg Ser Gln Ile Phe Tyr
  1               5                  10                  15

Tyr Ser Thr Gly Met Thr Val Gly Ile Val Ala Ser Leu Leu Ile Ile
             20                  25                  30

Ile Phe Ile Leu Ser Lys Phe Met Pro Lys Lys Ser Pro Ile Tyr Val
         35                  40                  45

Ile Leu Val Gly Gly Trp Ser Phe Ser Leu Tyr Leu Ile Gln Leu Val
     50                  55                  60

Phe Lys Asn Leu Gln Glu Ile Trp Arg Cys Tyr Trp Gln Tyr Leu Leu
 65                  70                  75                  80

Ser Tyr Val Leu Thr Val Gly Phe Met Ser Phe Ala Val Cys Tyr Lys
                 85                  90                  95

Tyr Gly Pro Leu Glu Asn Glu Arg Ser Ile Asn Leu Leu Thr Trp Thr
            100                 105                 110

Leu Gln Leu Met Gly Leu Cys Phe Met Tyr Ser Gly Ile Gln Ile Pro
        115                 120                 125

His Ile Ala Leu Ala Ile Ile Ile Ile Ala Leu Cys Thr Lys Asn Leu
    130                 135                 140

Glu His Pro Ile Gln Trp Leu Tyr Ile Thr Cys Arg Lys Val Cys Lys
145                 150                 155                 160

Gly Ala Glu Lys Pro Val Pro Pro Arg Leu Leu Thr Glu Glu Glu Tyr
                165                 170                 175

Arg Ile Gln Gly Glu Val Glu Thr Arg Lys Ala Leu Glu Glu Leu Arg
            180                 185                 190

Glu Phe Cys Asn Ser Pro Asp Cys Ser Ala Trp Lys Thr Val Ser Arg
        195                 200                 205

Ile Gln Ser Pro Lys Arg Phe Ala Asp Phe Val Glu Gly Ser Ser His
    210                 215                 220

Leu Thr Pro Asn Glu Val Ser Val His Glu Gln Glu Tyr Gly Leu Gly
225                 230                 235                 240

Ser Ile Ile Ala Gln Asp Glu Ile Tyr Glu Glu Ala Ser Ser Glu Glu
                245                 250                 255

Glu Asp Ser Tyr Ser Arg Cys Pro Ala Ile Thr Gln Asn Asn Phe Leu
            260                 265                 270

Thr 




<210> 2665
<211> 322
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (83)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2665
Met Ala Arg Cys Phe Ser Leu Val Leu Leu Leu Thr Ser Ile Trp Thr
  1               5                  10                  15

Thr Arg Leu Leu Val Gln Gly Ser Leu Arg Ala Glu Glu Leu Ser Ile
             20                  25                  30

Gln Val Ser Cys Arg Ile Met Gly Ile Thr Leu Val Ser Lys Lys Ala
         35                  40                  45

Asn Gln Gln Leu Asn Phe Thr Glu Ala Lys Glu Ala Cys Arg Leu Leu
     50                  55                  60

Gly Leu Ser Leu Ala Gly Lys Asp Gln Val Glu Thr Ala Leu Lys Ala
 65                  70                  75                  80

Ser Phe Xaa Thr Cys Ser Tyr Gly Trp Val Gly Asp Gly Phe Val Val
                 85                  90                  95

Ile Ser Arg Ile Ser Pro Asn Pro Lys Cys Gly Lys Asn Gly Val Gly
            100                 105                 110

Val Leu Ile Trp Lys Val Pro Val Ser Arg Gln Phe Ala Ala Tyr Cys
        115                 120                 125

Tyr Asn Ser Ser Asp Thr Trp Thr Asn Ser Cys Ile Pro Glu Ile Ile
    130                 135                 140

Thr Thr Lys Asp Pro Ile Phe Asn Thr Gln Thr Ala Thr Gln Thr Thr
145                 150                 155                 160

Glu Phe Ile Val Ser Asp Ser Thr Tyr Ser Val Ala Ser Pro Tyr Ser
                165                 170                 175

Thr Ile Pro Ala Pro Thr Thr Thr Pro Pro Ala Pro Ala Ser Thr Ser
            180                 185                 190

Ile Pro Arg Arg Lys Lys Leu Ile Cys Val Thr Glu Val Phe Met Glu
        195                 200                 205

Thr Ser Thr Met Ser Thr Glu Thr Glu Pro Phe Val Glu Asn Lys Ala
    210                 215                 220

Ala Phe Lys Asn Glu Ala Ala Gly Phe Gly Gly Val Pro Thr Ala Leu
225                 230                 235                 240

Leu Val Leu Ala Leu Leu Phe Phe Gly Ala Ala Ala Gly Leu Gly Phe
                245                 250                 255

Cys Tyr Val Lys Arg Tyr Val Lys Ala Phe Pro Phe Thr Asn Lys Asn
            260                 265                 270

Gln Gln Lys Glu Met Ile Glu Thr Lys Val Val Lys Glu Glu Lys Ala
        275                 280                 285

Asn Asp Ser Asn Pro Asn Glu Glu Ser Lys Lys Thr Asp Lys Asn Pro
    290                 295                 300

Glu Glu Ser Lys Ser Pro Ser Lys Thr Thr Val Arg Cys Leu Glu Ala
305                 310                 315                 320

Glu Val 




<210> 2666
<211> 299
<212> PRT
<213> Homo sapiens

<400> 2666
Met Gly Thr Lys Ala Gln Val Glu Arg Lys Leu Leu Cys Leu Phe Ile
  1               5                  10                  15

Leu Ala Ile Leu Leu Cys Ser Leu Ala Leu Gly Ser Val Thr Val His
             20                  25                  30

Ser Ser Glu Pro Glu Val Arg Ile Pro Glu Asn Asn Pro Val Lys Leu
         35                  40                  45

Ser Cys Ala Tyr Ser Gly Phe Ser Ser Pro Arg Val Glu Trp Lys Phe
     50                  55                  60

Asp Gln Gly Asp Thr Thr Arg Leu Val Cys Tyr Asn Asn Lys Ile Thr
 65                  70                  75                  80

Ala Ser Tyr Glu Asp Arg Val Thr Phe Leu Pro Thr Gly Ile Thr Phe
                 85                  90                  95

Lys Ser Val Thr Arg Glu Asp Thr Gly Thr Tyr Thr Cys Met Val Ser
            100                 105                 110

Glu Glu Gly Gly Asn Ser Tyr Gly Glu Val Lys Val Lys Leu Ile Val
        115                 120                 125

Leu Val Pro Pro Ser Lys Pro Thr Val Asn Ile Pro Ser Ser Ala Thr
    130                 135                 140

Ile Gly Asn Arg Ala Val Leu Thr Cys Ser Glu Gln Asp Gly Ser Pro
145                 150                 155                 160

Pro Ser Glu Tyr Thr Trp Phe Lys Asp Gly Ile Val Met Pro Thr Asn
                165                 170                 175

Pro Lys Ser Thr Arg Ala Phe Ser Asn Ser Ser Tyr Val Leu Asn Pro
            180                 185                 190

Thr Thr Gly Glu Leu Val Phe Asp Pro Leu Ser Ala Ser Asp Thr Gly
        195                 200                 205

Glu Tyr Ser Cys Glu Ala Arg Asn Gly Tyr Gly Thr Pro Met Thr Ser
    210                 215                 220

Asn Ala Val Arg Met Glu Ala Val Glu Arg Asn Val Gly Val Ile Val
225                 230                 235                 240

Ala Ala Val Leu Val Thr Leu Ile Leu Leu Gly Ile Leu Val Phe Gly
                245                 250                 255

Ile Trp Phe Ala Tyr Ser Arg Gly His Phe Asp Arg Thr Lys Lys Gly
            260                 265                 270

Thr Ser Ser Lys Lys Val Ile Tyr Ser Gln Pro Ser Ala Arg Ser Glu
        275                 280                 285

Gly Glu Phe Lys Gln Thr Ser Ser Phe Leu Val 
    290                 295



<210> 2667
<211> 557
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (392)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (419)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2667
Met Pro Leu Asp Asp Leu Asp Arg Glu Asp Glu Val Arg Leu Leu Lys
  1               5                  10                  15

Tyr Leu Phe Thr Leu Ile Arg Ala Gly Met Thr Glu Glu Ala Gln Arg
             20                  25                  30

Leu Cys Lys Arg Cys Gly Gln Ala Trp Arg Ala Ala Thr Leu Glu Gly
         35                  40                  45

Trp Lys Leu Tyr His Asp Pro Asn Val Asn Gly Gly Thr Glu Leu Glu
     50                  55                  60

Pro Val Glu Gly Asn Pro Tyr Arg Arg Ile Trp Lys Ile Ser Cys Trp
 65                  70                  75                  80

Arg Met Ala Glu Asp Glu Leu Phe Asn Arg Tyr Glu Arg Ala Ile Tyr
                 85                  90                  95

Ala Ala Leu Ser Gly Asn Leu Lys Gln Leu Leu Pro Val Cys Asp Thr
            100                 105                 110

Trp Glu Asp Thr Val Trp Ala Tyr Phe Arg Val Met Val Asp Ser Leu
        115                 120                 125

Val Glu Gln Glu Ile Gln Thr Ser Val Ala Thr Leu Asp Glu Thr Glu
    130                 135                 140

Glu Leu Pro Arg Glu Tyr Leu Gly Ala Asn Trp Thr Leu Glu Lys Val
145                 150                 155                 160

Phe Glu Glu Leu Gln Ala Thr Asp Lys Lys Arg Val Leu Glu Glu Asn
                165                 170                 175

Gln Glu His Tyr His Ile Val Gln Lys Phe Leu Ile Leu Gly Asp Ile
            180                 185                 190

Asp Gly Leu Met Asp Glu Phe Ser Lys Trp Leu Ser Lys Ser Arg Asn
        195                 200                 205

Asn Leu Pro Gly His Leu Leu Arg Phe Met Thr His Leu Ile Leu Phe
    210                 215                 220

Phe Arg Thr Leu Gly Leu Gln Thr Lys Glu Glu Val Ser Ile Glu Val
225                 230                 235                 240

Leu Lys Thr Tyr Ile Gln Leu Leu Ile Arg Glu Lys His Thr Asn Leu
                245                 250                 255

Ile Ala Phe Tyr Thr Cys His Leu Pro Gln Asp Leu Ala Val Ala Gln
            260                 265                 270

Tyr Ala Leu Phe Leu Glu Ser Val Thr Glu Phe Glu Gln Arg His His
        275                 280                 285

Cys Leu Glu Leu Ala Lys Glu Ala Asp Leu Asp Val Ala Thr Ile Thr
    290                 295                 300

Lys Thr Val Val Glu Asn Ile Arg Lys Lys Asp Asn Gly Glu Phe Ser
305                 310                 315                 320

His His Asp Leu Ala Pro Ala Leu Asp Thr Gly Thr Thr Glu Glu Asp
                325                 330                 335

Arg Leu Lys Ile Asp Val Ile Asp Trp Leu Val Phe Asp Pro Ala Gln
            340                 345                 350

Arg Ala Glu Ala Leu Lys Gln Gly Asn Ala Ile Met Arg Lys Phe Leu
        355                 360                 365

Ala Ser Lys Lys His Glu Ala Ala Lys Glu Val Phe Val Lys Ile Pro
    370                 375                 380

Gln Asp Ser Ile Ala Glu Ile Xaa Asn Gln Cys Glu Glu Gln Gly Met
385                 390                 395                 400

Glu Ser Pro Leu Pro Ala Glu Asp Asp Asn Ala Ile Arg Glu His Leu
                405                 410                 415

Cys Ile Xaa Ala Tyr Leu Glu Ala His Glu Thr Phe Asn Glu Trp Phe
            420                 425                 430

Lys His Met Asn Ser Val Pro Gln Lys Pro Ala Leu Ile Pro Gln Pro
        435                 440                 445

Thr Phe Thr Glu Lys Val Ala His Glu His Lys Glu Lys Lys Tyr Glu
    450                 455                 460

Met Asp Phe Gly Ile Trp Lys Gly His Leu Asp Ala Leu Thr Ala Asp
465                 470                 475                 480

Val Lys Glu Lys Met Tyr Asn Val Leu Leu Phe Val Asp Gly Gly Trp
                485                 490                 495

Met Val Asp Val Arg Glu Asp Ala Lys Glu Asp His Glu Arg Thr His
            500                 505                 510

Gln Met Val Leu Leu Arg Lys Leu Cys Leu Pro Met Leu Cys Phe Leu
        515                 520                 525

Leu His Thr Ile Leu His Ser Thr Gly Gln Tyr Ser Gly Met Pro Thr
    530                 535                 540

Val Ser Gln Ile Trp Tyr Pro Leu Ser Ala Thr Asn Cys 
545                 550                 555



<210> 2668
<211> 219
<212> PRT
<213> Homo sapiens

<400> 2668
Met Glu Ser Asn Leu Ser Gly Leu Val Pro Ala Ala Gly Leu Val Pro
  1               5                  10                  15

Ala Leu Pro Pro Ala Val Thr Leu Gly Leu Thr Ala Ala Tyr Thr Thr
             20                  25                  30

Leu Tyr Ala Leu Leu Phe Phe Ser Val Tyr Ala Gln Leu Trp Leu Val
         35                  40                  45

Leu Leu Tyr Gly His Lys Arg Leu Ser Tyr Gln Thr Val Phe Leu Ala
     50                  55                  60

Leu Cys Leu Leu Trp Ala Ala Leu Arg Thr Thr Leu Phe Ser Phe Tyr
 65                  70                  75                  80

Phe Arg Asp Thr Pro Arg Ala Asn Arg Leu Gly Pro Leu Pro Phe Trp
                 85                  90                  95

Leu Leu Tyr Cys Cys Pro Val Cys Leu Gln Phe Phe Thr Leu Thr Leu
            100                 105                 110

Met Asn Leu Tyr Phe Ala Gln Val Val Phe Lys Ala Lys Val Lys Arg
        115                 120                 125

Arg Pro Glu Met Ser Arg Gly Leu Leu Ala Val Arg Gly Ala Phe Val
    130                 135                 140

Gly Ala Ser Leu Leu Phe Leu Leu Val Asn Val Leu Cys Ala Val Leu
145                 150                 155                 160

Ser His Arg Arg Arg Ala Gln Pro Trp Ala Leu Leu Leu Val Arg Val
                165                 170                 175

Leu Val Ser Asp Ser Leu Phe Val Ile Cys Ala Leu Ser Leu Ala Ala
            180                 185                 190

Cys Leu Cys Leu Val Ala Arg Arg Ala Pro Ser Thr Ser Ile Tyr Leu
        195                 200                 205

Glu Ala Lys Gly Thr Ser Val Cys Gln Ala Ala 
    210                 215



<210> 2669
<211> 185
<212> PRT
<213> Homo sapiens

<400> 2669
Met Thr Met Ile Thr Pro Ser Ser Asn Thr Thr His Tyr Arg Glu Ser
  1               5                  10                  15

Trp Tyr Ala Cys Arg Tyr Arg Ser Gly Ile Pro Gly Ser Thr His Ala
             20                  25                  30

Ser Asp Arg Asn Gly His Gly Leu Asn Val Thr Phe Pro Pro Leu Leu
         35                  40                  45

Ser Gly Asn Asp Phe Gln Thr Val Glu Glu Gly Ser Asn Val Lys Leu
     50                  55                  60

Val Cys Asn Val Lys Ala Asn Pro Gln Ala Gln Met Met Trp Tyr Lys
 65                  70                  75                  80

Asn Ser Ser Leu Leu Asp Leu Glu Lys Ser Arg His Gln Ile Gln Gln
                 85                  90                  95

Thr Ser Glu Ser Phe Gln Leu Ser Ile Thr Lys Val Glu Lys Pro Asp
            100                 105                 110

Asn Gly Thr Tyr Ser Cys Ile Ala Lys Ser Ser Leu Lys Thr Glu Ser
        115                 120                 125

Leu Asp Phe His Leu Ile Val Lys Asp Lys Thr Val Gly Val Pro Ile
    130                 135                 140

Glu Pro Ile Ile Ala Ala Cys Val Val Ile Phe Leu Thr Leu Cys Phe
145                 150                 155                 160

Gly Leu Ile Ala Arg Arg Lys Lys Ile Met Lys Leu Cys Met Lys Asp
                165                 170                 175

Lys Asp Pro His Ser Glu Thr Ala Leu 
            180                 185



<210> 2670
<211> 232
<212> PRT
<213> Homo sapiens

<400> 2670
Met Leu Arg Ala Ala Leu Pro Ala Leu Leu Leu Pro Leu Leu Gly Leu
  1               5                  10                  15

Ala Ala Ala Ala Val Ala Asp Cys Pro Ser Ser Thr Trp Ile Gln Phe
             20                  25                  30

Gln Asp Ser Cys Tyr Ile Phe Leu Gln Glu Ala Ile Lys Val Glu Ser
         35                  40                  45

Ile Glu Asp Val Arg Asn Gln Cys Thr Asp His Gly Ala Asp Met Ile
     50                  55                  60

Ser Ile His Asn Glu Glu Glu Asn Ala Phe Ile Leu Asp Thr Leu Lys
 65                  70                  75                  80

Lys Gln Trp Lys Gly Pro Asp Asp Ile Leu Leu Gly Met Phe Tyr Asp
                 85                  90                  95

Thr Asp Asp Ala Ser Phe Lys Trp Phe Asp Asn Ser Asn Met Thr Phe
            100                 105                 110

Asp Lys Trp Thr Asp Gln Asp Asp Asp Glu Asp Leu Val Asp Thr Cys
        115                 120                 125

Ala Phe Leu His Ile Lys Thr Gly Glu Trp Lys Lys Gly Asn Cys Glu
    130                 135                 140

Val Ser Ser Val Glu Gly Thr Leu Cys Lys Thr Ala Ile Pro Tyr Lys
145                 150                 155                 160

Arg Lys Tyr Leu Ser Asp Asn His Ile Leu Ile Ser Ala Leu Val Ile
                165                 170                 175

Ala Ser Thr Val Ile Leu Thr Val Leu Gly Ala Ile Ile Trp Phe Leu
            180                 185                 190

Tyr Lys Lys His Ser Asp Ser Arg Phe Thr Thr Val Phe Ser Thr Ala
        195                 200                 205

Pro Gln Ser Pro Tyr Asn Glu Asp Cys Val Leu Val Val Gly Glu Glu
    210                 215                 220

Asn Glu Tyr Pro Val Gln Phe Asp 
225                 230



<210> 2671
<211> 139
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (21)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (59)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (72)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2671
Met Ala Asn Phe Lys Gly His Ala Leu Pro Gly Ser Phe Phe Leu Ile
  1               5                  10                  15

Ile Gly Leu Cys Xaa Ser Val Lys Tyr Pro Leu Lys Tyr Phe Ser His
             20                  25                  30

Thr Arg Lys Asn Ser Pro Leu His Tyr Tyr Gln Arg Leu Glu Ile Val
         35                  40                  45

Glu Ala Ala Ile Arg Thr Leu Phe Ser Val Xaa Gly Ile Leu Ala Glu
     50                  55                  60

Gln Phe Val Pro Asp Gly Pro Xaa Leu His Leu Tyr His Glu Asn His
 65                  70                  75                  80

Trp Ile Lys Leu Met Asn Xaa Gln His Ser Thr Met Tyr Xaa Ser Leu
                 85                  90                  95

Gln Ser Gln Glu Leu Leu Thr Cys Ser Leu Ser Gly Gln Pro Arg Ser
            100                 105                 110

Leu Gly Gly Gly Gln Thr Gly Xaa Gly Leu Trp His Ile His Gly Lys
        115                 120                 125

Val Phe Cys Gly Asn Gly Trp Glu Arg Lys Gly 
    130                 135



<210> 2672
<211> 124
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (120)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2672
Met Val Lys Val Thr Phe Asn Ser Ala Leu Ala Gln Lys Glu Ala Lys
  1               5                  10                  15

Lys Asp Glu Pro Lys Ser Gly Glu Glu Ala Leu Ile Ile Pro Pro Asp
             20                  25                  30

Ala Val Ala Val Asp Cys Lys Asp Pro Asp Asp Val Val Pro Val Gly
         35                  40                  45

Gln Arg Arg Ala Trp Cys Trp Cys Met Cys Phe Gly Leu Ala Phe Met
     50                  55                  60

Leu Ala Gly Val Ile Leu Gly Gly Ala Tyr Leu Tyr Lys Tyr Phe Ala
 65                  70                  75                  80

Leu Xaa Pro Asp Asp Val Tyr Tyr Cys Gly Ile Lys Tyr Ile Lys Asp
                 85                  90                  95

Asp Val Ile Leu Asn Glu Pro Ser Ala Asp Ala Pro Ala Ala Leu Tyr
            100                 105                 110

Gln Thr Ile Glu Glu Asn Ile Xaa Ile Phe Glu Xaa 
        115                 120



<210> 2673
<211> 105
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (92)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (98)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2673
Met Lys Leu Ile Tyr Gln Gly Arg Leu Leu Gln Asp Pro Ala Arg Thr
  1               5                  10                  15

Leu Arg Ser Leu Asn Ile Thr Asp Asn Cys Val Ile His Cys His Arg
             20                  25                  30

Ser Pro Pro Gly Ser Ala Val Pro Gly Pro Ser Ala Ser Leu Xaa Pro
         35                  40                  45

Ser Ala Thr Glu Pro Pro Ser Leu Val Ser Met Trp Gly Xaa Leu Met
     50                  55                  60

Val Leu Xaa Leu Trp Cys Cys Trp Val Xaa Ser Gly Thr Xaa Glu Ile
 65                  70                  75                  80

Asn Tyr Arg Gln Phe Phe Lys Ala Thr Ala Asn Xaa Ser Xaa Val Gly
                 85                  90                  95

Asn Xaa Arg Leu Leu Lys Leu Pro Lys 
            100                 105



<210> 2674
<211> 561
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (223)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (511)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (521)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (533)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (550)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2674
Met Pro Leu Leu Leu Ala Tyr Leu Lys Ser Val Pro Leu Gly His Thr
  1               5                  10                  15

His His Leu Ala Lys Ala Cys Tyr Ala Leu Glu Asn Phe Val Glu Asn
             20                  25                  30

Leu Gly Pro Lys Val Gln Pro Tyr Leu Pro Glu Leu Met Glu Cys Met
         35                  40                  45

Leu Gln Leu Leu Arg Asn Pro Ser Ser Pro Arg Ala Lys Glu Leu Ala
     50                  55                  60

Val Ser Ala Leu Gly Ala Ile Ala Thr Ala Ala Gln Val Ser Leu Leu
 65                  70                  75                  80

Pro Tyr Phe Pro Ala Ile Met Glu His Leu Arg Glu Phe Leu Leu Thr
                 85                  90                  95

Gly Arg Glu Asp Leu Gln Pro Val Gln Ile Gln Ser Leu Glu Thr Leu
            100                 105                 110

Gly Val Leu Ala Arg Ala Val Gly Glu Pro Met Arg Pro Leu Ala Glu
        115                 120                 125

Glu Cys Cys Gln Leu Gly Leu Gly Leu Cys Asp Gln Val Asp Asp Ala
    130                 135                 140

Asp Leu Arg Arg Cys Thr Tyr Ser Leu Phe Ala Ala Leu Ser Gly Leu
145                 150                 155                 160

Met Gly Glu Gly Leu Ala Pro His Leu Glu Gln Ile Thr Thr Leu Met
                165                 170                 175

Leu Leu Ser Leu Arg Ser Thr Glu Gly Ile Val Pro Gln Tyr Asp Gly
            180                 185                 190

Ser Ser Ser Phe Leu Leu Phe Asp Asp Glu Ser Asp Gly Glu Glu Glu
        195                 200                 205

Glu Glu Leu Met Asp Glu Asp Val Glu Glu Glu Asp Asp Ser Xaa Ile
    210                 215                 220

Ser Gly Tyr Ser Val Glu Asn Ala Phe Phe Asp Glu Lys Glu Asp Thr
225                 230                 235                 240

Cys Ala Ala Val Gly Glu Ile Ser Val Asn Thr Ser Val Ala Phe Leu
                245                 250                 255

Pro Tyr Met Glu Ser Val Phe Glu Glu Val Phe Lys Leu Leu Glu Cys
            260                 265                 270

Pro His Leu Asn Val Arg Lys Ala Ala His Glu Ala Leu Gly Gln Phe
        275                 280                 285

Cys Cys Ala Leu His Lys Ala Cys Gln Ser Cys Pro Ser Glu Pro Asn
    290                 295                 300

Thr Ala Ala Leu Gln Ala Ala Leu Ala Arg Val Val Pro Ser Tyr Met
305                 310                 315                 320

Gln Ala Val Asn Arg Glu Arg Glu Arg Gln Val Val Met Ala Val Leu
                325                 330                 335

Glu Ala Leu Thr Gly Val Leu Arg Ser Cys Gly Thr Leu Thr Leu Lys
            340                 345                 350

Pro Pro Gly Arg Leu Ala Glu Leu Cys Gly Val Leu Lys Ala Val Leu
        355                 360                 365

Gln Arg Lys Thr Ala Cys Gln Asp Thr Asp Glu Glu Glu Glu Glu Glu
    370                 375                 380

Asp Asp Asp Gln Ala Glu Tyr Asp Ala Met Leu Leu Glu His Ala Gly
385                 390                 395                 400

Glu Ala Ile Pro Ala Leu Ala Ala Ala Ala Gly Gly Asp Ser Phe Ala
                405                 410                 415

Pro Phe Phe Ala Gly Phe Leu Pro Leu Leu Val Cys Lys Thr Lys Gln
            420                 425                 430

Gly Cys Thr Val Ala Glu Lys Ser Phe Ala Val Gly Thr Leu Ala Glu
        435                 440                 445

Thr Ile Gln Gly Leu Gly Ala Ala Ser Ala Gln Phe Val Ser Arg Leu
    450                 455                 460

Leu Pro Val Leu Leu Ser Thr Ala Gln Glu Ala Asp Pro Glu Val Arg
465                 470                 475                 480

Ser Asn Ala Ile Phe Gly Met Gly Val Leu Ala Glu His Gly Gly His
                485                 490                 495

Pro Ala Gln Glu His Phe Pro Lys Leu Leu Gly Leu Leu Phe Xaa Leu
            500                 505                 510

Leu Ala Arg Glu Arg His Asp Arg Xaa Arg Asp Asn Ile Cys Gly Ala
        515                 520                 525

Leu Ala Arg Leu Xaa Met Ala Ser Pro Pro Gly Asn Gln Ser Pro Lys
    530                 535                 540

Cys Trp Leu Pro Tyr Xaa Met Pro Cys Thr Glu Glu Asp Leu Glu Asn
545                 550                 555                 560

Gly 




<210> 2675
<211> 453
<212> PRT
<213> Homo sapiens

<400> 2675
Met Gly Ser Val Leu Gly Leu Cys Ser Met Ala Ser Trp Ile Pro Cys
  1               5                  10                  15

Leu Cys Gly Ser Ala Pro Cys Leu Leu Cys Arg Cys Cys Pro Ser Gly
             20                  25                  30

Asn Asn Ser Thr Val Thr Arg Leu Ile Tyr Ala Leu Phe Leu Leu Val
         35                  40                  45

Gly Val Cys Val Ala Cys Val Met Leu Ile Pro Gly Met Glu Glu Gln
     50                  55                  60

Leu Asn Lys Ile Pro Gly Phe Cys Glu Asn Glu Lys Gly Val Val Pro
 65                  70                  75                  80

Cys Asn Ile Leu Val Gly Tyr Lys Ala Val Tyr Arg Leu Cys Phe Gly
                 85                  90                  95

Leu Ala Met Phe Tyr Leu Leu Leu Ser Leu Leu Met Ile Lys Val Lys
            100                 105                 110

Ser Ser Ser Asp Pro Arg Ala Ala Val His Asn Gly Phe Trp Phe Phe
        115                 120                 125

Lys Phe Ala Ala Ala Ile Ala Ile Ile Ile Gly Ala Phe Phe Ile Pro
    130                 135                 140

Glu Gly Thr Phe Thr Thr Val Trp Phe Tyr Val Gly Met Ala Gly Ala
145                 150                 155                 160

Phe Cys Phe Ile Leu Ile Gln Leu Val Leu Leu Ile Asp Phe Ala His
                165                 170                 175

Ser Trp Asn Glu Ser Trp Val Glu Lys Met Glu Glu Gly Asn Ser Arg
            180                 185                 190

Cys Trp Tyr Ala Ala Leu Leu Ser Ala Thr Ala Leu Asn Tyr Leu Leu
        195                 200                 205

Ser Leu Val Ala Ile Val Leu Phe Phe Val Tyr Tyr Thr His Pro Ala
    210                 215                 220

Ser Cys Ser Glu Asn Lys Ala Phe Ile Ser Val Asn Met Leu Leu Cys
225                 230                 235                 240

Val Gly Ala Ser Val Met Ser Ile Leu Pro Lys Ile Gln Glu Ser Gln
                245                 250                 255

Pro Arg Ser Gly Leu Leu Gln Ser Ser Val Ile Thr Val Tyr Thr Met
            260                 265                 270

Tyr Leu Thr Trp Ser Ala Met Thr Asn Glu Pro Glu Thr Asn Cys Asn
        275                 280                 285

Pro Ser Leu Leu Ser Ile Ile Gly Tyr Asn Thr Thr Ser Thr Val Pro
    290                 295                 300

Lys Glu Gly Gln Ser Val Gln Trp Trp His Ala Gln Gly Ile Ile Gly
305                 310                 315                 320

Leu Ile Leu Phe Leu Leu Cys Val Phe Tyr Ser Ser Ile Arg Thr Ser
                325                 330                 335

Asn Asn Ser Gln Val Asn Lys Leu Thr Leu Thr Ser Asp Glu Ser Thr
            340                 345                 350

Leu Ile Glu Asp Gly Gly Ala Arg Ser Asp Gly Ser Leu Glu Asp Gly
        355                 360                 365

Asp Asp Val His Arg Ala Val Asp Asn Glu Arg Asp Gly Val Thr Tyr
    370                 375                 380

Ser Tyr Ser Phe Phe His Phe Met Leu Phe Leu Ala Ser Leu Tyr Ile
385                 390                 395                 400

Met Met Thr Leu Thr Asn Trp Tyr Arg Tyr Glu Pro Ser Arg Glu Met
                405                 410                 415

Lys Ser Gln Trp Thr Ala Val Trp Val Lys Ile Ser Ser Ser Trp Ile
            420                 425                 430

Gly Ile Val Leu Tyr Val Trp Thr Leu Val Ala Pro Leu Val Leu Thr
        435                 440                 445

Asn Arg Asp Phe Asp 
    450



<210> 2676
<211> 170
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (75)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (111)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (168)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2676
Met Cys Thr His Ile His Ser His Val Cys Xaa Gly Ala His Leu Pro
  1               5                  10                  15

Gln Arg Leu Gln Pro Arg Arg Ala Ser His Ile Arg Gly Met Asn Gly
             20                  25                  30

Arg Ser Val Pro Pro Ala Val Cys Ser Leu Pro Pro Glu Glu Ser Ser
         35                  40                  45

Arg Asp Ser Asp Gly Gly Ala Gly Gly Ala His Ala Val Cys Ser Arg
     50                  55                  60

His Pro Val Arg Val Lys Gly Leu Glu Gly Xaa Glu Met Glu Ser Ala
 65                  70                  75                  80

Arg Glu Asn Ile Asp Leu Gln Pro Gly Ser Ser Asp Pro Arg Ser Gln
                 85                  90                  95

Pro Ile Asn Leu Asn His Tyr Ala Thr Lys Lys Ser Val Ala Xaa Ser
            100                 105                 110

Met Leu Asp Val Ala Leu Phe Met Ser Asn Ala Met Xaa Leu Lys Ala
        115                 120                 125

Val Leu Glu Gln Gly Pro Ser Ser His Tyr Tyr Thr Thr Leu Val Thr
    130                 135                 140

Leu Ile Ser Leu Ser Leu Leu Leu Gln Leu Val His Arg Cys Leu Leu
145                 150                 155                 160

Val Val Ile Ala Arg Leu Asn Xaa Met Xaa 
                165                 170



<210> 2677
<211> 530
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (2)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2677
Met Xaa Met Ile Thr Pro Ser Phe Asn Thr Thr His Tyr Arg Glu Ser
  1               5                  10                  15

Trp Tyr Ala Cys Arg Tyr Arg Ser Gly Ile Pro Gly Ser Thr His Ala
             20                  25                  30

Ser Ala Ser Thr Thr Val Pro Gly Leu Ser Glu Glu Ser Thr Thr Phe
         35                  40                  45

Tyr Ser Ser Pro Gly Ser Thr Glu Thr Thr Ala Phe Ser His Ser Asn
     50                  55                  60

Thr Met Ser Ile His Ser Gln Gln Ser Thr Pro Phe Pro Asp Ser Pro
 65                  70                  75                  80

Gly Phe Thr His Thr Val Leu Pro Ala Thr Leu Thr Thr Thr Asp Ile
                 85                  90                  95

Gly Gln Glu Ser Thr Ala Phe His Ser Ser Ser Asp Ala Thr Gly Thr
            100                 105                 110

Thr Pro Leu Pro Ala Arg Ser Thr Ala Ser Asp Leu Val Gly Glu Pro
        115                 120                 125

Thr Thr Phe Tyr Ile Ser Pro Ser Pro Thr Tyr Thr Thr Leu Phe Pro
    130                 135                 140

Ala Ser Ser Ser Thr Ser Gly Leu Thr Glu Glu Ser Thr Thr Phe His
145                 150                 155                 160

Thr Ser Pro Ser Phe Thr Ser Thr Ile Val Ser Thr Glu Ser Leu Glu
                165                 170                 175

Thr Leu Ala Pro Gly Leu Cys Gln Glu Gly Gln Ile Trp Asn Gly Lys
            180                 185                 190

Gln Cys Val Cys Pro Gln Gly Tyr Val Gly Tyr Gln Cys Leu Ser Pro
        195                 200                 205

Leu Glu Ser Phe Pro Val Glu Thr Pro Glu Lys Leu Asn Ala Thr Leu
    210                 215                 220

Gly Met Thr Val Lys Val Thr Tyr Arg Asn Phe Thr Glu Lys Met Asn
225                 230                 235                 240

Asp Ala Ser Ser Gln Glu Tyr Gln Asn Phe Ser Thr Leu Phe Lys Asn
                245                 250                 255

Arg Met Asp Val Val Leu Lys Gly Asp Asn Leu Pro Gln Tyr Arg Gly
            260                 265                 270

Val Asn Ile Arg Arg Leu Leu Asn Gly Ser Ile Val Val Lys Asn Asp
        275                 280                 285

Val Ile Leu Glu Ala Asp Tyr Thr Leu Glu Tyr Glu Glu Leu Phe Glu
    290                 295                 300

Asn Leu Ala Glu Ile Val Lys Ala Lys Ile Met Asn Glu Thr Arg Thr
305                 310                 315                 320

Thr Leu Leu Asp Pro Asp Ser Cys Arg Lys Ala Ile Leu Cys Tyr Ser
                325                 330                 335

Glu Glu Asp Thr Phe Val Asp Ser Ser Val Thr Pro Gly Phe Asp Phe
            340                 345                 350

Gln Glu Gln Cys Thr Gln Lys Ala Ala Glu Gly Tyr Thr Gln Phe Tyr
        355                 360                 365

Tyr Val Asp Val Leu Asp Gly Lys Leu Ala Cys Val Asn Lys Cys Thr
    370                 375                 380

Lys Gly Thr Lys Ser Gln Met Asn Cys Asn Leu Gly Thr Cys Gln Leu
385                 390                 395                 400

Gln Arg Ser Gly Pro Arg Cys Leu Cys Pro Asn Thr Asn Thr His Trp
                405                 410                 415

Tyr Trp Gly Glu Thr Cys Glu Phe Asn Ile Ala Lys Ser Leu Val Tyr
            420                 425                 430

Gly Ile Val Gly Ala Val Met Ala Val Leu Leu Leu Ala Leu Ile Ile
        435                 440                 445

Leu Ile Ile Leu Phe Ser Leu Ser Gln Arg Lys Arg His Arg Glu Gln
    450                 455                 460

Tyr Asp Val Pro Gln Glu Trp Arg Lys Glu Gly Thr Pro Gly Ile Phe
465                 470                 475                 480

Gln Lys Thr Ala Ile Trp Glu Asp Gln Asn Leu Arg Glu Ser Arg Phe
                485                 490                 495

Gly Leu Glu Asn Ala Tyr Asn Asn Phe Arg Pro Thr Leu Glu Thr Val
            500                 505                 510

Asp Ser Gly Thr Glu Leu His Ile Gln Arg Pro Glu Met Val Ala Ser
        515                 520                 525

Thr Val 
    530



<210> 2678
<211> 204
<212> PRT
<213> Homo sapiens

<400> 2678
Met Val Cys Gly Gly Phe Ala Cys Ser Lys Asn Cys Leu Cys Ala Leu
  1               5                  10                  15

Asn Leu Leu Tyr Thr Leu Val Ser Leu Leu Leu Ile Gly Ile Ala Ala
             20                  25                  30

Trp Gly Ile Gly Phe Gly Leu Ile Ser Ser Leu Arg Val Val Gly Val
         35                  40                  45

Val Ile Ala Val Gly Ile Phe Leu Phe Leu Ile Ala Leu Val Gly Leu
     50                  55                  60

Ile Gly Ala Val Lys His His Gln Val Leu Leu Phe Phe Tyr Met Ile
 65                  70                  75                  80

Ile Leu Leu Leu Val Phe Ile Val Gln Phe Ser Val Ser Cys Ala Cys
                 85                  90                  95

Leu Ala Leu Asn Gln Glu Gln Gln Gly Gln Leu Leu Glu Val Gly Trp
            100                 105                 110

Asn Asn Thr Ala Ser Ala Arg Asn Asp Ile Gln Arg Asn Leu Asn Cys
        115                 120                 125

Cys Gly Phe Arg Ser Val Asn Pro Asn Asp Thr Cys Leu Ala Ser Cys
    130                 135                 140

Val Lys Ser Asp His Ser Cys Ser Pro Cys Ala Pro Ile Ile Gly Glu
145                 150                 155                 160

Tyr Ala Gly Glu Val Leu Arg Phe Val Gly Gly Ile Gly Leu Phe Phe
                165                 170                 175

Ser Phe Thr Glu Ile Leu Gly Val Trp Leu Thr Tyr Arg Tyr Arg Asn
            180                 185                 190

Gln Lys Asp Pro Arg Ala Asn Pro Ser Ala Phe Leu 
        195                 200



<210> 2679
<211> 543
<212> PRT
<213> Homo sapiens

<400> 2679
Met Ala Val Ser Glu Arg Arg Gly Leu Gly Arg Gly Ser Pro Ala Glu
  1               5                  10                  15

Trp Gly Gln Arg Leu Leu Leu Val Leu Leu Leu Gly Gly Cys Ser Gly
             20                  25                  30

Arg Ile His Arg Leu Ala Leu Thr Gly Glu Lys Arg Ala Asp Ile Gln
         35                  40                  45

Leu Asn Ser Phe Gly Phe Tyr Thr Asn Gly Ser Leu Glu Val Glu Leu
     50                  55                  60

Ser Val Leu Arg Leu Gly Leu Arg Glu Ala Glu Glu Lys Ser Leu Leu
 65                  70                  75                  80

Val Gly Phe Ser Leu Ser Arg Val Arg Ser Gly Arg Val Arg Ser Tyr
                 85                  90                  95

Ser Thr Arg Asp Phe Gln Asp Cys Pro Leu Gln Lys Asn Ser Ser Ser
            100                 105                 110

Phe Leu Val Leu Phe Leu Ile Asn Thr Lys Asp Leu Gln Val Gln Val
        115                 120                 125

Arg Lys Tyr Gly Glu Gln Lys Thr Leu Phe Ile Phe Pro Gly Leu Leu
    130                 135                 140

Pro Glu Ala Pro Ser Lys Pro Gly Leu Pro Lys Pro Gln Ala Thr Val
145                 150                 155                 160

Pro Arg Lys Val Asp Gly Gly Gly Thr Ser Ala Ala Ser Lys Pro Lys
                165                 170                 175

Ser Thr Pro Ala Val Ile Gln Gly Pro Ser Gly Lys Asp Lys Asp Leu
            180                 185                 190

Val Leu Gly Leu Ser His Leu Asn Asn Ser Tyr Asn Phe Ser Phe His
        195                 200                 205

Val Val Ile Gly Ser Gln Ala Glu Glu Gly Gln Tyr Ser Leu Asn Phe
    210                 215                 220

His Asn Cys Asn Asn Ser Val Pro Gly Lys Glu His Pro Phe Asp Ile
225                 230                 235                 240

Thr Val Met Ile Arg Glu Lys Asn Pro Asp Gly Phe Leu Ser Ala Ala
                245                 250                 255

Glu Met Pro Leu Phe Lys Leu Tyr Met Val Met Ser Ala Cys Phe Leu
            260                 265                 270

Ala Ala Gly Ile Phe Trp Val Ser Ile Leu Cys Arg Asn Thr Tyr Ser
        275                 280                 285

Val Phe Lys Ile His Trp Leu Met Ala Ala Leu Ala Phe Thr Lys Ser
    290                 295                 300

Ile Ser Leu Leu Phe His Ser Ile Asn Tyr Tyr Phe Ile Asn Ser Gln
305                 310                 315                 320

Gly His Pro Ile Glu Gly Leu Ala Val Met Tyr Tyr Ile Ala His Leu
                325                 330                 335

Leu Lys Gly Ala Leu Leu Phe Ile Thr Ile Ala Leu Ile Gly Ser Gly
            340                 345                 350

Trp Ala Phe Ile Lys Tyr Val Leu Ser Asp Lys Glu Lys Lys Val Phe
        355                 360                 365

Gly Ile Val Ile Pro Met Gln Val Leu Ala Asn Val Ala Tyr Ile Ile
    370                 375                 380

Ile Glu Ser Arg Glu Glu Gly Ala Ser Asp Tyr Val Leu Trp Lys Glu
385                 390                 395                 400

Ile Leu Phe Leu Val Asp Leu Ile Cys Cys Gly Ala Ile Leu Phe Pro
                405                 410                 415

Val Val Trp Ser Ile Arg His Leu Gln Asp Ala Ser Gly Thr Asp Gly
            420                 425                 430

Lys Val Ala Val Asn Leu Ala Lys Leu Lys Leu Phe Arg His Tyr Tyr
        435                 440                 445

Val Met Val Ile Cys Tyr Val Tyr Phe Thr Arg Ile Ile Ala Ile Leu
    450                 455                 460

Leu Gln Val Ala Val Pro Phe Gln Trp Gln Trp Leu Tyr Gln Leu Leu
465                 470                 475                 480

Val Glu Gly Ser Thr Leu Ala Phe Phe Val Leu Thr Gly Tyr Lys Phe
                485                 490                 495

Gln Pro Thr Gly Asn Asn Pro Tyr Leu Gln Leu Pro Gln Glu Asp Glu
            500                 505                 510

Glu Asp Val Gln Met Glu Gln Val Met Thr Asp Ser Gly Phe Arg Glu
        515                 520                 525

Gly Leu Ser Lys Val Asn Lys Thr Ala Ser Gly Arg Glu Leu Leu 
    530                 535                 540



<210> 2680
<211> 165
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2680
Met Leu Lys Val Gly Ala Thr Leu Thr Gly Val Gly Glu Leu Val Leu
  1               5                  10                  15

Asp Asn Asn Ser Val Arg Leu Gln Pro Pro Lys Gln Gly Met Gln Tyr
             20                  25                  30

Tyr Leu Ser Ser Gln Asp Phe Asp Ser Leu Leu Gln Arg Gln Glu Ser
         35                  40                  45

Ser Val Arg Leu Trp Lys Val Leu Ala Leu Val Phe Gly Phe Ala Thr
     50                  55                  60

Cys Ala Thr Leu Phe Phe Ile Leu Arg Lys Gln Tyr Leu Gln Arg Gln
 65                  70                  75                  80

Glu Arg Leu Arg Leu Lys Gln Met Gln Glu Glu Phe Gln Glu His Glu
                 85                  90                  95

Ala Gln Leu Leu Ser Arg Ala Lys Pro Glu Asp Xaa Glu Ser Leu Lys
            100                 105                 110

Ser Ala Cys Val Val Cys Leu Ser Ser Phe Lys Ser Cys Val Phe Leu
        115                 120                 125

Glu Cys Gly His Val Cys Ser Cys Thr Glu Cys Tyr Arg Ala Leu Pro
    130                 135                 140

Glu Pro Lys Lys Cys Pro Ile Cys Arg Gln Ala Ile Thr Arg Val Ile
145                 150                 155                 160

Pro Leu Tyr Asn Ser 
                165



<210> 2681
<211> 246
<212> PRT
<213> Homo sapiens

<400> 2681
Met Ala Ala Ala Ala Ala Thr Lys Ile Leu Leu Cys Leu Pro Leu Leu
  1               5                  10                  15

Leu Leu Leu Ser Gly Trp Ser Arg Ala Gly Arg Ala Asp Pro His Ser
             20                  25                  30

Leu Cys Tyr Asp Ile Thr Val Ile Pro Lys Phe Arg Pro Gly Pro Arg
         35                  40                  45

Trp Cys Ala Val Gln Gly Gln Val Asp Glu Lys Thr Phe Leu His Tyr
     50                  55                  60

Asp Cys Gly Asn Lys Thr Val Thr Pro Val Ser Pro Leu Gly Lys Lys
 65                  70                  75                  80

Leu Asn Val Thr Thr Ala Trp Lys Ala Gln Asn Pro Val Leu Arg Glu
                 85                  90                  95

Val Val Asp Ile Leu Thr Glu Gln Leu Arg Asp Ile Gln Leu Glu Asn
            100                 105                 110

Tyr Thr Pro Lys Glu Pro Leu Thr Leu Gln Ala Arg Met Ser Cys Glu
        115                 120                 125

Gln Lys Ala Glu Gly His Ser Ser Gly Ser Trp Gln Phe Ser Phe Asp
    130                 135                 140

Gly Gln Ile Phe Leu Leu Phe Asp Ser Glu Lys Arg Met Trp Thr Thr
145                 150                 155                 160

Val His Pro Gly Ala Arg Lys Met Lys Glu Lys Trp Glu Asn Asp Lys
                165                 170                 175

Val Val Ala Met Ser Phe His Tyr Phe Ser Met Gly Asp Cys Ile Gly
            180                 185                 190

Trp Leu Glu Asp Phe Leu Met Gly Met Asp Ser Thr Leu Glu Pro Ser
        195                 200                 205

Ala Gly Ala Pro Leu Ala Met Ser Ser Gly Thr Thr Gln Leu Arg Ala
    210                 215                 220

Thr Ala Thr Thr Leu Ile Leu Cys Cys Leu Leu Ile Ile Leu Pro Cys
225                 230                 235                 240

Phe Ile Leu Pro Gly Ile 
                245



<210> 2682
<211> 408
<212> PRT
<213> Homo sapiens

<400> 2682
Met Gly His Met Leu Tyr Leu Leu Gly Asn Ile Asn Lys Arg Thr Met
  1               5                  10                  15

His Lys Tyr Glu Gln Glu Ser Lys Lys Ala Gly Lys Ala Ser Phe Ala
             20                  25                  30

Tyr Ala Trp Val Leu Asp Glu Thr Gly Glu Glu Arg Glu Arg Gly Val
         35                  40                  45

Thr Met Asp Val Gly Met Thr Lys Phe Glu Thr Thr Thr Lys Val Ile
     50                  55                  60

Thr Leu Met Asp Ala Pro Gly His Lys Asp Phe Ile Pro Asn Met Ile
 65                  70                  75                  80

Thr Gly Ala Ala Gln Ala Asp Val Ala Val Leu Val Val Asp Ala Ser
                 85                  90                  95

Arg Gly Glu Phe Glu Ala Gly Phe Glu Thr Gly Gly Gln Thr Arg Glu
            100                 105                 110

His Gly Leu Leu Val Arg Ser Leu Gly Val Thr Gln Leu Ala Val Ala
        115                 120                 125

Val Asn Lys Met Asp Gln Val Asn Trp Gln Gln Glu Arg Phe Gln Glu
    130                 135                 140

Ile Thr Gly Lys Leu Gly His Phe Leu Lys Gln Ala Gly Phe Lys Glu
145                 150                 155                 160

Ser Asp Val Gly Phe Ile Pro Thr Ser Gly Leu Ser Gly Glu Asn Leu
                165                 170                 175

Ile Thr Arg Ser Gln Ser Ser Glu Leu Thr Lys Trp Tyr Lys Gly Leu
            180                 185                 190

Cys Leu Leu Glu Gln Ile Asp Ser Phe Lys Pro Pro Gln Arg Ser Ile
        195                 200                 205

Asp Lys Pro Phe Arg Leu Cys Val Ser Asp Val Phe Lys Asp Gln Gly
    210                 215                 220

Ser Gly Phe Cys Ile Thr Gly Lys Ile Glu Ala Gly Tyr Ile Gln Thr
225                 230                 235                 240

Gly Asp Arg Leu Leu Ala Met Pro Pro Asn Glu Thr Cys Thr Val Lys
                245                 250                 255

Gly Ile Thr Leu His Asp Glu Pro Val Asp Trp Ala Ala Ala Gly Asp
            260                 265                 270

His Val Ser Leu Thr Leu Val Gly Met Asp Ile Ile Lys Ile Asn Val
        275                 280                 285

Gly Cys Ile Phe Cys Gly Pro Lys Val Pro Ile Lys Ala Cys Thr Arg
    290                 295                 300

Phe Arg Ala Arg Ile Leu Ile Phe Asn Ile Glu Ile Pro Ile Thr Lys
305                 310                 315                 320

Gly Phe Pro Val Leu Leu His Tyr Gln Thr Val Ser Glu Pro Ala Val
                325                 330                 335

Ile Lys Arg Leu Ile Ser Val Leu Asn Lys Ser Thr Gly Glu Val Thr
            340                 345                 350

Lys Lys Lys Pro Lys Phe Leu Thr Lys Gly Gln Asn Ala Leu Val Glu
        355                 360                 365

Leu Gln Thr Gln Arg Pro Ile Ala Leu Glu Leu Tyr Lys Asp Phe Lys
    370                 375                 380

Glu Leu Gly Arg Phe Met Leu Arg Tyr Gly Gly Ser Thr Ile Ala Ala
385                 390                 395                 400

Gly Val Val Thr Glu Ile Lys Glu 
                405



<210> 2683
<211> 192
<212> PRT
<213> Homo sapiens

<400> 2683
Met Val Arg Ala Gly Ala Val Gly Ala His Leu Pro Ala Ser Gly Leu
  1               5                  10                  15

Asp Ile Phe Gly Asp Leu Lys Lys Met Asn Lys Arg Gln Leu Tyr Tyr
             20                  25                  30

Gln Val Leu Asn Phe Ala Met Ile Val Ser Ser Ala Leu Met Ile Trp
         35                  40                  45

Lys Gly Leu Ile Val Leu Thr Gly Ser Glu Ser Pro Ile Val Val Val
     50                  55                  60

Leu Ser Gly Ser Met Glu Pro Ala Phe His Arg Gly Asp Leu Leu Phe
 65                  70                  75                  80

Leu Thr Asn Phe Arg Glu Asp Pro Ile Arg Ala Gly Glu Ile Val Val
                 85                  90                  95

Phe Lys Val Glu Gly Arg Asp Ile Pro Ile Val His Arg Val Ile Lys
            100                 105                 110

Val His Glu Lys Asp Asn Gly Asp Ile Lys Phe Leu Thr Lys Gly Asp
        115                 120                 125

Asn Asn Glu Val Asp Asp Arg Gly Leu Tyr Lys Glu Gly Gln Asn Trp
    130                 135                 140

Leu Glu Lys Lys Asp Val Val Gly Arg Ala Arg Gly Phe Leu Pro Tyr
145                 150                 155                 160

Val Gly Met Val Thr Ile Ile Met Asn Asp Tyr Pro Lys Phe Lys Tyr
                165                 170                 175

Ala Leu Leu Ala Val Met Gly Ala Tyr Val Leu Leu Lys Arg Glu Ser
            180                 185                 190






<210> 2684
<211> 459
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (433)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (434)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2684
Met Tyr Gly Ile Val Tyr Thr Arg Pro Cys Ser Gly Asp Ala Asn Cys
  1               5                  10                  15

Ile Gln Pro Tyr Leu Ala Arg Arg Pro Lys Leu Gln Leu Ser Val Tyr
             20                  25                  30

Thr Thr Thr Arg Ser His Leu Gly Ala Glu Asn Asn Ile Asp Leu Val
         35                  40                  45

Leu Asn Val Glu Asp Phe Asp Val Glu Ser Lys Phe Glu Arg Thr Val
     50                  55                  60

Asn Val Ser Val Pro Lys Lys Thr Arg Asn Asn Gly Thr Leu Tyr Ala
 65                  70                  75                  80

Tyr Ile Phe Leu His His Ala Gly Val Leu Pro Trp His Asp Gly Lys
                 85                  90                  95

Gln Val His Leu Val Ser Pro Leu Thr Thr Tyr Met Val Pro Lys Pro
            100                 105                 110

Glu Glu Ile Asn Leu Leu Thr Gly Glu Ser Asp Thr Gln Gln Ile Glu
        115                 120                 125

Ala Glu Lys Lys Pro Thr Ser Ala Leu Asp Glu Pro Val Ser His Trp
    130                 135                 140

Arg Pro Arg Leu Ala Leu Asn Val Met Ala Asp Asn Phe Val Phe Asp
145                 150                 155                 160

Gly Ser Ser Leu Pro Ala Asp Val His Arg Tyr Met Lys Met Ile Gln
                165                 170                 175

Leu Gly Lys Thr Val His Tyr Leu Pro Ile Leu Phe Ile Asp Gln Leu
            180                 185                 190

Ser Asn Arg Val Lys Asp Leu Met Val Ile Asn Arg Ser Thr Thr Glu
        195                 200                 205

Leu Pro Leu Thr Val Ser Tyr Asp Lys Val Ser Leu Gly Arg Leu Arg
    210                 215                 220

Phe Trp Ile His Met Gln Asp Ala Val Tyr Ser Leu Gln Gln Phe Gly
225                 230                 235                 240

Phe Ser Glu Lys Asp Ala Asp Glu Val Lys Gly Ile Phe Val Asp Thr
                245                 250                 255

Asn Leu Tyr Phe Leu Ala Leu Thr Phe Phe Val Ala Ala Phe His Leu
            260                 265                 270

Leu Phe Asp Phe Leu Ala Phe Lys Asn Asp Ile Ser Phe Trp Lys Lys
        275                 280                 285

Lys Lys Ser Met Ile Gly Met Ser Thr Lys Ala Val Leu Trp Arg Cys
    290                 295                 300

Phe Ser Thr Val Val Ile Phe Leu Phe Leu Leu Asp Glu Gln Thr Ser
305                 310                 315                 320

Leu Leu Val Leu Val Pro Ala Gly Val Gly Ala Ala Ile Glu Leu Trp
                325                 330                 335

Lys Val Lys Lys Ala Leu Lys Met Thr Ile Phe Trp Arg Gly Leu Met
            340                 345                 350

Pro Glu Phe Gln Phe Gly Thr Tyr Ser Glu Ser Glu Arg Lys Thr Glu
        355                 360                 365

Glu Tyr Asp Thr Gln Ala Met Lys Tyr Leu Ser Tyr Leu Leu Tyr Pro
    370                 375                 380

Leu Cys Val Gly Gly Ala Val Tyr Ser Leu Leu Asn Ile Lys Tyr Lys
385                 390                 395                 400

Ser Trp Tyr Ser Trp Leu Ile Asn Ser Phe Val Asn Gly Val Tyr Ala
                405                 410                 415

Phe Gly Phe Leu Phe Met Leu Pro Gln Leu Phe Val Asn Tyr Lys Val
            420                 425                 430

Xaa Xaa Cys Val Leu Pro Ala Ala Gly Pro Arg Leu Leu Cys Cys Pro
        435                 440                 445

Gln Leu Thr Trp Ala Cys Leu Ser Cys Phe Ser 
    450                 455



<210> 2685
<211> 159
<212> PRT
<213> Homo sapiens

<400> 2685
Met Gly Val Leu Ala Glu His Gly Gly His Pro Ala Gln Glu His Phe
  1               5                  10                  15

Pro Lys Leu Leu Gly Leu Leu Phe Pro Leu Leu Ala Arg Glu Arg His
             20                  25                  30

Asp Arg Val Arg Asp Asn Ile Cys Gly Ala Leu Ala Arg Leu Leu Met
         35                  40                  45

Ala Ser Pro Thr Arg Lys Pro Glu Pro Gln Val Leu Ala Ala Leu Leu
     50                  55                  60

His Ala Leu Pro Leu Lys Glu Asp Leu Glu Glu Trp Val Thr Ile Gly
 65                  70                  75                  80

Arg Leu Phe Ser Phe Leu Tyr Gln Ser Ser Pro Asp Gln Val Ile Asp
                 85                  90                  95

Val Ala Pro Glu Leu Leu Arg Ile Cys Ser Leu Ile Leu Ala Asp Asn
            100                 105                 110

Lys Ile Pro Pro Asp Thr Lys Ala Ala Leu Leu Leu Leu Leu Thr Phe
        115                 120                 125

Leu Ala Lys Gln His Thr Asp Ser Phe Gln Ala Ala Leu Gly Ser Leu
    130                 135                 140

Pro Val Asp Lys Ala Gln Glu Leu Gln Ala Val Leu Gly Leu Ser 
145                 150                 155



<210> 2686
<211> 257
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (103)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2686
Met Glu Asp Leu Ile Arg Pro Trp Phe Pro Glu Phe Ser Glu Ala Arg
  1               5                  10                  15

Ala Ile Met Leu Ser Arg Gly Leu Ala Phe Gly Tyr Gly Leu Leu Cys
             20                  25                  30

Leu Gly Met Ala Tyr Ile Ser Ser Gln Met Gly Pro Val Leu Gln Ala
         35                  40                  45

Ala Ile Ser Ile Phe Gly Met Val Gly Gly Pro Leu Leu Gly Leu Phe
     50                  55                  60

Cys Leu Gly Met Phe Phe Pro Cys Ala Asn Pro Pro Gly Ala Val Val
 65                  70                  75                  80

Gly Leu Leu Ala Gly Leu Val Met Ala Phe Trp Ile Gly Ile Gly Ser
                 85                  90                  95

Ile Val Thr Ser Met Gly Xaa Ser Met Pro Pro Ser Pro Ser Asn Gly
            100                 105                 110

Ser Ser Phe Ser Leu Pro Thr Asn Leu Thr Val Ala Thr Val Thr Thr
        115                 120                 125

Leu Met Pro Leu Thr Thr Phe Ser Lys Pro Thr Gly Leu Gln Arg Phe
    130                 135                 140

Tyr Ser Leu Ser Tyr Leu Trp Tyr Ser Ala His Asn Ser Thr Thr Val
145                 150                 155                 160

Ile Val Val Gly Leu Ile Val Ser Leu Leu Thr Gly Arg Met Arg Gly
                165                 170                 175

Arg Ser Leu Asn Pro Ala Thr Ile Tyr Pro Val Leu Pro Lys Leu Leu
            180                 185                 190

Ser Leu Leu Pro Leu Ser Cys Gln Lys Arg Leu His Cys Arg Ser Tyr
        195                 200                 205

Gly Gln Asp His Leu Asp Thr Gly Leu Phe Pro Glu Lys Pro Arg Asn
    210                 215                 220

Gly Val Leu Gly Asp Ser Arg Asp Lys Glu Ala Met Ala Leu Asp Gly
225                 230                 235                 240

Thr Ala Tyr Gln Gly Ser Ser Ser Thr Cys Ile Leu Gln Glu Thr Ser
                245                 250                 255

Leu 




<210> 2687
<211> 267
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2687
Met Val Lys Ile Ser Phe Gln Pro Ala Val Ala Gly Ile Lys Gly Asp
  1               5                  10                  15

Lys Ala Asp Lys Ala Ser Ala Ser Ala Pro Ala Pro Ala Ser Ala Thr
             20                  25                  30

Glu Ile Leu Leu Thr Pro Ala Arg Glu Glu Gln Pro Pro Gln His Arg
         35                  40                  45

Ser Lys Arg Gly Xaa Ser Val Gly Gly Val Cys Tyr Leu Ser Met Gly
     50                  55                  60

Met Val Val Leu Leu Met Gly Leu Val Phe Ala Ser Val Tyr Ile Tyr
 65                  70                  75                  80

Arg Tyr Phe Phe Leu Ala Gln Leu Ala Arg Asp Asn Phe Phe Arg Cys
                 85                  90                  95

Gly Val Leu Tyr Glu Asp Ser Leu Ser Ser Gln Val Arg Thr Gln Met
            100                 105                 110

Glu Leu Glu Glu Asp Val Lys Ile Tyr Leu Asp Glu Asn Tyr Glu Arg
        115                 120                 125

Ile Asn Val Pro Val Pro Gln Phe Gly Gly Gly Asp Pro Ala Asp Ile
    130                 135                 140

Ile His Asp Phe Gln Arg Gly Leu Thr Ala Tyr His Asp Ile Ser Leu
145                 150                 155                 160

Asp Lys Cys Tyr Val Ile Glu Leu Asn Thr Thr Ile Val Leu Pro Pro
                165                 170                 175

Arg Asn Phe Trp Glu Leu Leu Met Asn Val Lys Arg Gly Thr Tyr Leu
            180                 185                 190

Pro Gln Thr Tyr Ile Ile Gln Glu Glu Met Val Val Thr Glu His Val
        195                 200                 205

Ser Asp Lys Glu Ala Leu Gly Ser Phe Ile Tyr His Leu Cys Asn Gly
    210                 215                 220

Lys Asp Thr Tyr Arg Leu Arg Arg Arg Ala Thr Arg Arg Arg Ile Asn
225                 230                 235                 240

Lys Arg Gly Ala Lys Asn Cys Asn Ala Ile Arg His Phe Glu Asn Thr
                245                 250                 255

Phe Val Val Glu Thr Leu Ile Cys Gly Val Val 
            260                 265



<210> 2688
<211> 224
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2688
Met Leu Thr Ile Trp Leu Ala His Val Thr Phe Cys Thr Ala Tyr Val
  1               5                  10                  15

Ala Val Val Ile Ser Ser Arg Leu Arg Glu Leu Asp Arg Ser Ile Glu
             20                  25                  30

Glu Ala Ala Met Asp Leu Gly Ala Thr Pro Leu Lys Val Phe Phe Val
         35                  40                  45

Ile Thr Leu Pro Met Ile Met Pro Ala Ile Ile Ser Gly Trp Leu Leu
     50                  55                  60

Ala Phe Thr Leu Ser Leu Asp Asp Leu Val Ile Ala Ser Phe Val Ser
 65                  70                  75                  80

Gly Pro Gly Ala Thr Thr Leu Pro Met Leu Val Phe Ser Ser Val Arg
                 85                  90                  95

Met Gly Val Asn Pro Glu Ile Asn Ala Leu Ala Ile Arg Trp Pro Ala
            100                 105                 110

Arg Gln Gln Thr Pro Ala Trp Arg Phe Ser Asn Leu Ala Thr Gly Ser
        115                 120                 125

Asn Arg Trp Arg Ile Leu Lys Tyr Ser Cys Ala Ser Asn Leu Pro Pro
    130                 135                 140

Pro Val Asn Ala Glu Met Val Ala Asp Val Arg Val Leu Gly Ala Ile
145                 150                 155                 160

Gly Val Val Glu Thr Thr His Pro Val Asn Met Ala Ala Leu Gln Lys
                165                 170                 175

Phe Phe Val Glu Gln Gly Val Trp Ile Arg Pro Phe Gly Lys Leu Ile
            180                 185                 190

Tyr Leu Met Pro Pro Tyr Ile Ile Leu Pro Gln Gln Leu Gln Arg Leu
        195                 200                 205

Thr Ala Ala Val Asn Arg Ala Xaa Gln Asp Glu Thr Phe Phe Cys Gln
    210                 215                 220






<210> 2689
<211> 109
<212> PRT
<213> Homo sapiens

<400> 2689
Met Ser Thr Ser Asp Leu Glu Leu Leu Thr Ser Lys Met Lys Tyr Arg
  1               5                  10                  15

Phe Ser Ser Val Val His Asn Asp Val Gln Ala Phe Phe His Leu Phe
             20                  25                  30

Thr Glu Phe Ser Asn His Leu Leu Cys Val Glu Ile Gly Gly Phe Ser
         35                  40                  45

Gly Cys Phe Ser Glu Val Asn Asp Leu Leu Gln Ser Leu Ser Lys Lys
     50                  55                  60

Phe Gln Leu Lys Ser Gln Lys His Lys Val Gln Glu Thr Thr Arg Arg
 65                  70                  75                  80

Trp Ile Phe Ser Val Phe Glu Ile Leu Tyr Phe Leu Leu Ile Ser Phe
                 85                  90                  95

Thr His Phe Asn Phe Thr Thr Ala Asn Leu Leu Arg Tyr 
            100                 105



<210> 2690
<211> 424
<212> PRT
<213> Homo sapiens

<400> 2690
Met Glu Lys Gln Cys Cys Ser His Pro Val Ile Cys Ser Leu Ser Thr
  1               5                  10                  15

Met Tyr Thr Phe Leu Leu Gly Ala Ile Phe Ile Ala Leu Ser Ser Ser
             20                  25                  30

Arg Ile Leu Leu Val Lys Tyr Ser Ala Asn Glu Glu Asn Lys Tyr Asp
         35                  40                  45

Tyr Leu Pro Thr Thr Val Asn Val Cys Ser Glu Leu Val Lys Leu Val
     50                  55                  60

Phe Cys Val Leu Val Ser Phe Cys Val Ile Lys Lys Asp His Gln Ser
 65                  70                  75                  80

Arg Asn Leu Lys Tyr Ala Ser Trp Lys Glu Phe Ser Asp Phe Met Lys
                 85                  90                  95

Trp Ser Ile Pro Ala Phe Leu Tyr Phe Leu Asp Asn Leu Ile Val Phe
            100                 105                 110

Tyr Val Leu Ser Tyr Leu Gln Pro Ala Met Ala Val Ile Phe Ser Asn
        115                 120                 125

Phe Ser Ile Ile Thr Thr Ala Leu Leu Phe Arg Ile Val Leu Lys Arg
    130                 135                 140

Arg Leu Asn Trp Ile Gln Trp Ala Ser Leu Leu Thr Leu Phe Leu Ser
145                 150                 155                 160

Ile Val Ala Leu Thr Ala Gly Thr Lys Thr Leu Gln His Asn Leu Ala
                165                 170                 175

Gly Arg Gly Phe His His Asp Ala Phe Phe Ser Pro Ser Asn Ser Cys
            180                 185                 190

Leu Leu Phe Arg Ser Glu Cys Pro Arg Lys Asp Asn Cys Thr Ala Lys
        195                 200                 205

Glu Trp Thr Phe Pro Glu Ala Lys Trp Asn Thr Thr Ala Arg Val Phe
    210                 215                 220

Ser His Ile Arg Leu Gly Met Gly His Val Leu Ile Ile Val Gln Cys
225                 230                 235                 240

Phe Ile Ser Ser Met Ala Asn Ile Tyr Asn Glu Lys Ile Leu Lys Glu
                245                 250                 255

Gly Asn Gln Leu Thr Glu Ser Ile Phe Ile Gln Asn Ser Lys Leu Tyr
            260                 265                 270

Phe Phe Gly Ile Leu Phe Asn Gly Leu Thr Leu Gly Leu Gln Arg Ser
        275                 280                 285

Asn Arg Asp Gln Ile Lys Asn Cys Gly Phe Phe Tyr Gly His Ser Ala
    290                 295                 300

Phe Ser Val Ala Leu Ile Phe Val Thr Ala Phe Gln Gly Leu Ser Val
305                 310                 315                 320

Ala Phe Ile Leu Lys Phe Leu Asp Asn Met Phe His Val Leu Met Ala
                325                 330                 335

Gln Val Thr Thr Val Ile Ile Thr Thr Val Ser Val Leu Val Phe Asp
            340                 345                 350

Phe Arg Pro Ser Leu Glu Phe Phe Leu Glu Ala Pro Ser Val Leu Leu
        355                 360                 365

Ser Ile Phe Ile Tyr Asn Ala Ser Lys Pro Gln Val Pro Glu Tyr Ala
    370                 375                 380

Pro Arg Gln Glu Arg Ile Arg Asp Leu Ser Gly Asn Leu Trp Glu Arg
385                 390                 395                 400

Ser Ser Gly Asp Gly Glu Glu Leu Glu Arg Leu Thr Lys Pro Lys Ser
                405                 410                 415

Asp Glu Ser Asp Glu Asp Thr Phe 
            420



<210> 2691
<211> 259
<212> PRT
<213> Homo sapiens

<400> 2691
Met Ser Lys Phe Arg Tyr Asn Pro Ser Glu Ser Pro Phe Ala Met Ala
  1               5                  10                  15

Gln Ile Gln Ser Leu Ser Leu Arg Ala Val Ser Gly Ala Met Gly Leu
             20                  25                  30

Gly Phe Leu Leu Ser Met Leu Phe Phe Ile Glu Gln Asn Leu Val Ala
         35                  40                  45

Ala Leu Val Asn Ala Pro Glu Asn Arg Leu Val Lys Gly Thr Ala Tyr
     50                  55                  60

His Trp Asp Leu Leu Leu Leu Ala Ile Ile Asn Thr Gly Leu Ser Leu
 65                  70                  75                  80

Phe Gly Leu Pro Trp Ile His Ala Ala Tyr Pro His Ser Pro Leu His
                 85                  90                  95

Val Arg Ala Leu Ala Leu Val Glu Glu Arg Val Glu Asn Gly His Ile
            100                 105                 110

Tyr Asp Thr Ile Val Asn Val Lys Glu Thr Arg Leu Thr Ser Leu Gly
        115                 120                 125

Ala Ser Val Leu Val Gly Leu Ser Leu Leu Leu Leu Pro Val Pro Leu
    130                 135                 140

Gln Trp Ile Pro Lys Pro Val Leu Tyr Gly Leu Phe Leu Tyr Ile Ala
145                 150                 155                 160

Leu Thr Ser Leu Asp Gly Asn Gln Leu Val Gln Arg Val Ala Leu Leu
                165                 170                 175

Leu Lys Glu Gln Thr Ala Tyr Pro Pro Thr His Tyr Ile Arg Arg Val
            180                 185                 190

Pro Gln Arg Lys Ile His Tyr Phe Thr Gly Leu Gln Val Leu Gln Leu
        195                 200                 205

Leu Leu Leu Cys Ala Phe Gly Met Ser Ser Leu Pro Tyr Met Lys Met
    210                 215                 220

Ile Phe Pro Leu Ile Met Ile Ala Met Ile Pro Ile Arg Tyr Ile Leu
225                 230                 235                 240

Leu Pro Arg Ile Ile Glu Ala Lys Tyr Leu Asp Val Met Asp Ala Glu
                245                 250                 255

His Arg Pro 




<210> 2692
<211> 311
<212> PRT
<213> Homo sapiens

<400> 2692
Met Thr Met Ile Thr Pro Ser Ser Asn Thr Thr His Tyr Arg Glu Ser
  1               5                  10                  15

Trp Tyr Ala Cys Arg Tyr Arg Ser Gly Ile Pro Gly Ser Thr His Ala
             20                  25                  30

Ser Ala Trp Leu Lys Arg Cys Arg Cys Arg Tyr Cys Arg Cys Arg Glu
         35                  40                  45

Asn Ala Glu Pro Ser Arg Ala Gly Trp Ala Ala Ala Ala Arg Ala Ala
     50                  55                  60

Thr Gly Thr Arg Phe Pro Ser Ala Ala Ala Ala Ala Met Ala Arg Leu
 65                  70                  75                  80

Ala Asp Tyr Phe Ile Val Val Gly Tyr Asp His Glu Lys Pro Gly Ser
                 85                  90                  95

Gly Glu Gly Leu Gly Lys Ile Ile Gln Arg Phe Pro Gln Lys Asp Trp
            100                 105                 110

Asp Asp Thr Pro Phe Pro Gln Gly Ile Glu Leu Phe Cys Gln Pro Gly
        115                 120                 125

Gly Trp Gln Leu Ser Arg Glu Arg Lys Gln Pro Thr Phe Phe Val Val
    130                 135                 140

Val Leu Thr Asp Ile Asp Ser Asp Arg His Tyr Cys Ser Cys Leu Thr
145                 150                 155                 160

Phe Tyr Glu Ala Glu Ile Asn Leu Gln Gly Thr Lys Lys Glu Glu Ile
                165                 170                 175

Glu Gly Glu Ala Lys Val Ser Gly Leu Ile Gln Pro Ala Glu Val Phe
            180                 185                 190

Ala Pro Lys Ser Leu Val Leu Val Ser Arg Leu Tyr Tyr Pro Glu Ile
        195                 200                 205

Phe Arg Ala Cys Leu Gly Leu Ile Tyr Thr Val Tyr Val Asp Ser Leu
    210                 215                 220

Asn Val Ser Leu Glu Ser Leu Ile Ala Asn Leu Cys Ala Cys Leu Val
225                 230                 235                 240

Pro Ala Ala Gly Gly Ser Gln Lys Leu Phe Ser Leu Gly Ala Gly Asp
                245                 250                 255

Arg Gln Leu Ile Gln Thr Pro Leu His Asp Ser Leu Pro Ile Thr Gly
            260                 265                 270

Thr Ser Val Ala Leu Leu Phe Gln Gln Leu Gly Thr Val Ala His Ala
        275                 280                 285

Cys Asn Leu Ser Thr Leu Gly Gly Arg Gly Gly Gln Leu Thr Arg Ser
    290                 295                 300

Gly Asp Arg Asp His Pro Gly 
305                 310



<210> 2693
<211> 220
<212> PRT
<213> Homo sapiens

<400> 2693
Met Thr Thr Met Gln Gly Met Glu Gln Ala Met Pro Gly Ala Gly Pro
  1               5                  10                  15

Gly Val Pro Gln Leu Gly Asn Met Ala Val Ile His Ser His Leu Trp
             20                  25                  30

Lys Gly Leu Gln Glu Lys Phe Leu Lys Gly Glu Pro Lys Val Leu Gly
         35                  40                  45

Val Val Gln Ile Leu Thr Ala Leu Met Ser Leu Ser Met Gly Ile Thr
     50                  55                  60

Met Met Cys Met Ala Ser Asn Thr Tyr Gly Ser Asn Pro Ile Ser Val
 65                  70                  75                  80

Tyr Ile Gly Tyr Thr Ile Trp Gly Ser Val Met Phe Ile Ile Ser Gly
                 85                  90                  95

Ser Leu Ser Ile Ala Ala Gly Ile Arg Thr Thr Lys Gly Leu Val Arg
            100                 105                 110

Gly Ser Leu Gly Met Asn Ile Thr Ser Ser Val Leu Ala Ala Ser Gly
        115                 120                 125

Ile Leu Ile Asn Thr Phe Ser Leu Ala Phe Tyr Ser Phe His His Pro
    130                 135                 140

Tyr Cys Asn Tyr Tyr Gly Asn Ser Asn Asn Cys His Gly Thr Met Ser
145                 150                 155                 160

Ile Leu Met Gly Leu Asp Gly Met Val Leu Leu Leu Ser Val Leu Glu
                165                 170                 175

Phe Cys Ile Ala Val Ser Leu Ser Ala Phe Gly Cys Lys Val Leu Cys
            180                 185                 190

Cys Thr Pro Gly Gly Val Val Leu Ile Leu Pro Ser His Ser His Met
        195                 200                 205

Ala Glu Thr Ala Ser Pro Thr Pro Leu Asn Glu Val 
    210                 215                 220



<210> 2694
<211> 183
<212> PRT
<213> Homo sapiens

<400> 2694
Met Ala Ser Arg Ala Gly Pro Arg Ala Ala Gly Thr Asp Gly Ser Asp
  1               5                  10                  15

Phe Gln His Arg Glu Arg Val Ala Met His Tyr Gln Met Ser Val Thr
             20                  25                  30

Leu Lys Tyr Glu Ile Lys Lys Leu Ile Tyr Val His Leu Val Ile Trp
         35                  40                  45

Leu Leu Leu Val Ala Lys Met Ser Val Gly His Leu Arg Leu Leu Ser
     50                  55                  60

His Asp Gln Val Ala Met Pro Tyr Gln Trp Glu Tyr Pro Tyr Leu Leu
 65                  70                  75                  80

Ser Ile Leu Pro Ser Leu Leu Gly Leu Leu Ser Phe Pro Arg Asn Asn
                 85                  90                  95

Ile Ser Tyr Leu Val Leu Ser Met Ile Ser Met Gly Leu Phe Ser Ile
            100                 105                 110

Ala Pro Leu Ile Tyr Gly Ser Met Glu Met Phe Pro Ala Ala Gln Gln
        115                 120                 125

Leu Tyr Arg His Gly Lys Ala Tyr Arg Phe Leu Phe Gly Phe Ser Ala
    130                 135                 140

Val Ser Ile Met Tyr Leu Val Leu Val Leu Ala Val Gln Val His Ala
145                 150                 155                 160

Trp Gln Leu Tyr Tyr Ser Lys Lys Leu Leu Asp Ser Trp Phe Thr Ser
                165                 170                 175

Thr Gln Glu Lys Lys His Lys 
            180



<210> 2695
<211> 137
<212> PRT
<213> Homo sapiens

<400> 2695
Met Gly Trp Leu Arg Pro Gly Pro Arg Pro Leu Cys Pro Pro Ala Arg
  1               5                  10                  15

Ala Ser Trp Ala Phe Ser His Arg Phe Pro Ser Pro Leu Ala Pro Arg
             20                  25                  30

Arg Ser Pro Thr Pro Phe Phe Met Ala Ser Leu Leu Cys Cys Gly Pro
         35                  40                  45

Lys Leu Ala Ala Cys Gly Ile Val Leu Ser Ala Trp Gly Val Ile Met
     50                  55                  60

Leu Ile Met Leu Gly Ile Phe Phe Asn Val His Ser Ala Val Leu Ile
 65                  70                  75                  80

Glu Asp Val Pro Phe Thr Glu Lys Asp Phe Glu Asn Gly Pro Gln Asn
                 85                  90                  95

Ile Tyr Asn Leu Tyr Glu Gln Val Ser Tyr Asn Cys Phe Ile Ala Ala
            100                 105                 110

Gly Leu Tyr Leu Leu Leu Gly Gly Phe Ser Phe Cys Gln Val Arg Leu
        115                 120                 125

Asn Lys Arg Lys Glu Tyr Met Val Arg 
    130                 135



<210> 2696
<211> 140
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (125)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2696
Met Cys Gln Lys Glu Glu Phe Pro Cys Ser Arg Asn Gly Val Cys Tyr
  1               5                  10                  15

Pro Arg Ser Asp Arg Cys Asn Tyr Gln Asn His Cys Pro Asn Gly Ser
             20                  25                  30

Asp Glu Lys Asn Cys Phe Phe Cys Gln Pro Gly Asn Phe His Cys Lys
         35                  40                  45

Asn Asn Arg Cys Val Phe Glu Ser Trp Val Cys Asp Ser Gln Asp Asp
     50                  55                  60

Cys Gly Asp Gly Ser Asp Glu Glu Asn Cys Pro Val Ile Val Pro Thr
 65                  70                  75                  80

Arg Val Ile Thr Ala Ala Val Ile Gly Ser Leu Ile Cys Gly Leu Leu
                 85                  90                  95

Leu Val Ile Ala Leu Gly Cys Thr Cys Lys Leu Tyr Ser Leu Arg Met
            100                 105                 110

Phe Glu Arg Arg Ser Phe Glu Thr Gln Leu Ser Arg Xaa Glu Ala Glu
        115                 120                 125

Leu Val Arg Arg Glu Xaa Leu Pro Xaa Met Xaa Asn 
    130                 135                 140



<210> 2697
<211> 406
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (209)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2697
Met Ala Glu Asn Gly Lys Asn Cys Asp Gln Arg Arg Val Ala Met Asn
  1               5                  10                  15

Lys Glu His His Asn Gly Asn Phe Thr Asp Pro Ser Ser Val Asn Glu
             20                  25                  30

Lys Lys Arg Arg Glu Arg Glu Glu Arg Gln Asn Ile Val Leu Trp Arg
         35                  40                  45

Gln Pro Leu Ile Thr Leu Gln Tyr Phe Ser Leu Glu Ile Leu Val Ile
     50                  55                  60

Leu Lys Glu Trp Thr Ser Lys Leu Trp His Arg Gln Ser Ile Val Val
 65                  70                  75                  80

Ser Phe Leu Leu Leu Leu Ala Val Leu Ile Ala Thr Tyr Tyr Val Glu
                 85                  90                  95

Gly Val His Gln Gln Tyr Val Gln Arg Ile Glu Lys Gln Phe Leu Leu
            100                 105                 110

Tyr Ala Tyr Trp Ile Gly Leu Gly Ile Leu Ser Ser Val Gly Leu Gly
        115                 120                 125

Thr Gly Leu His Thr Phe Leu Leu Tyr Leu Gly Pro His Ile Ala Ser
    130                 135                 140

Val Thr Leu Ala Ala Tyr Glu Cys Asn Ser Val Asn Phe Pro Glu Pro
145                 150                 155                 160

Pro Tyr Pro Asp Gln Ile Ile Cys Pro Asp Glu Glu Gly Thr Glu Gly
                165                 170                 175

Thr Ile Ser Leu Trp Ser Ile Ile Ser Lys Val Arg Ile Glu Ala Cys
            180                 185                 190

Met Trp Gly Ile Gly Thr Ala Ile Gly Glu Leu Pro Pro Tyr Phe Met
        195                 200                 205

Xaa Arg Ala Ala Arg Leu Ser Gly Ala Glu Pro Asp Asp Glu Glu Tyr
    210                 215                 220

Gln Glu Phe Glu Glu Met Leu Glu His Ala Glu Ser Ala Gln Asp Phe
225                 230                 235                 240

Ala Ser Arg Ala Lys Leu Ala Val Gln Lys Leu Val Gln Lys Val Gly
                245                 250                 255

Phe Phe Gly Ile Leu Ala Cys Ala Ser Ile Pro Asn Pro Leu Phe Asp
            260                 265                 270

Leu Ala Gly Ile Thr Cys Gly His Phe Leu Val Pro Phe Trp Thr Phe
        275                 280                 285

Phe Gly Ala Thr Leu Ile Gly Lys Ala Ile Ile Lys Met His Ile Gln
    290                 295                 300

Lys Ile Phe Val Ile Ile Thr Phe Ser Lys His Ile Val Glu Gln Met
305                 310                 315                 320

Val Ala Phe Ile Gly Ala Val Pro Gly Ile Gly Pro Ser Leu Gln Lys
                325                 330                 335

Pro Phe Gln Glu Tyr Leu Glu Ala Gln Arg Gln Lys Leu His His Lys
            340                 345                 350

Ser Glu Met Gly Thr Pro Gln Gly Glu Asn Trp Leu Ser Trp Met Phe
        355                 360                 365

Glu Lys Leu Val Val Val Met Val Cys Tyr Phe Ile Leu Ser Ile Ile
    370                 375                 380

Asn Ser Met Ala Gln Ser Tyr Ala Lys Arg Ile Gln Gln Arg Leu Asn
385                 390                 395                 400

Ser Glu Glu Lys Thr Lys 
                405



<210> 2698
<211> 181
<212> PRT
<213> Homo sapiens

<400> 2698
Met Ala Pro Thr Leu Ala Thr Ala His Arg Arg Arg Trp Trp Met Ala
  1               5                  10                  15

Cys Thr Ala Val Leu Glu Asn Leu Leu Phe Ser Ala Val Leu Leu Gly
             20                  25                  30

Trp Gly Ser Leu Leu Ile Met Leu Lys Ser Glu Gly Phe Tyr Ser Tyr
         35                  40                  45

Leu Cys Thr Glu Pro Glu Asn Val Thr Asn Gly Thr Val Gly Gly Thr
     50                  55                  60

Ala Glu Pro Gly His Glu Glu Val Ser Trp Met Asn Gly Trp Leu Ser
 65                  70                  75                  80

Cys Gln Ala Gln Asp Glu Met Leu Asn Leu Ala Phe Thr Val Gly Ser
                 85                  90                  95

Phe Leu Leu Ser Ala Ile Thr Leu Pro Leu Gly Ile Val Met Asp Lys
            100                 105                 110

Tyr Gly Pro Arg Lys Leu Arg Leu Leu Gly Ser Ala Cys Phe Ala Val
        115                 120                 125

Ser Cys Leu Leu Ile Ala Tyr Gly Ala Ser Lys Pro Asn Ala Leu Ser
    130                 135                 140

Val Leu Ile Phe Ile Ala Leu Ala Leu Asn Gly Phe Gly Gly Met Cys
145                 150                 155                 160

Met Thr Phe Thr Ser Leu Thr Leu Pro Asn Met Phe Gly Asp Leu Arg
                165                 170                 175

Ser Thr Phe Ile Ala 
            180



<210> 2699
<211> 342
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (183)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (221)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2699
Met Gly Ser Trp Ser Ala Ala Gly Val Ala Asp Gln Ser Val Thr Val
  1               5                  10                  15

Leu Thr Gly Ile Lys Asn Ala Val Gly Glu Asn Gly Lys Val Leu Tyr
             20                  25                  30

Ala Lys Gly Ala Asn Val Thr Ser Asp Lys Gly Ile Ile Asp Phe Leu
         35                  40                  45

Asn Gln Tyr Glu Glu Ala Val Lys Val Asp Pro Arg Ser Pro Gln Glu
     50                  55                  60

Met Ile Asp Glu Ala Val Gln Thr Ala Lys Gln Ser Asp Val Val Val
 65                  70                  75                  80

Ala Val Val Gly Glu Ala Gln Gly Met Ala His Glu Ala Ser Ser Arg
                 85                  90                  95

Thr Asp Ile Thr Ile Pro Gln Ser Gln Arg Asp Leu Ile Ala Ala Leu
            100                 105                 110

Lys Ala Thr Gly Lys Pro Leu Val Leu Val Leu Met Asn Gly Arg Pro
        115                 120                 125

Leu Ala Leu Val Lys Glu Asp Gln Gln Ala Asp Ala Ile Leu Glu Thr
    130                 135                 140

Trp Phe Ala Gly Thr Glu Gly Gly Asn Ala Ile Ala Asp Val Leu Phe
145                 150                 155                 160

Gly Asp Tyr Asn Pro Ser Gly Lys Leu Pro Met Ser Phe Pro Arg Ser
                165                 170                 175

Val Gly Gln Ile Pro Val Xaa Tyr Ser His Leu Asn Thr Gly Arg Pro
            180                 185                 190

Tyr Asn Ala Asp Lys Pro Asn Lys Tyr Thr Ser Arg Tyr Phe Asp Glu
        195                 200                 205

Ala Asn Gly Ala Leu Tyr Pro Phe Gly Tyr Gly Leu Xaa Tyr Thr Thr
    210                 215                 220

Phe Thr Val Ser Asp Val Lys Leu Ser Ala Pro Thr Met Lys Arg Asp
225                 230                 235                 240

Gly Lys Val Thr Ala Ser Val Gln Val Thr Asn Thr Gly Lys Arg Glu
                245                 250                 255

Gly Ala Thr Val Val Gln Met Tyr Leu Gln Asp Val Thr Ala Ser Met
            260                 265                 270

Ser Arg Pro Val Lys Gln Leu Lys Gly Phe Glu Lys Ile Thr Leu Lys
        275                 280                 285

Pro Gly Glu Thr Gln Thr Val Ser Phe Pro Ile Asp Ile Glu Ala Leu
    290                 295                 300

Lys Phe Trp Asn Gln Gln Met Lys Tyr Asp Ala Glu Pro Gly Lys Phe
305                 310                 315                 320

Asn Val Phe Ile Gly Thr Asp Ser Ala Arg Val Lys Lys Gly Glu Phe
                325                 330                 335

Glu Val Ala Val Met Leu 
            340



<210> 2700
<211> 248
<212> PRT
<213> Homo sapiens

<400> 2700
Met Ala Pro Lys Ala Ala Lys Gly Ala Lys Pro Glu Pro Ala Pro Ala
  1               5                  10                  15

Pro Pro Pro Pro Gly Ala Lys Pro Glu Glu Asp Lys Lys Asp Gly Lys
             20                  25                  30

Glu Pro Ser Asp Lys Pro Gln Lys Ala Val Gln Asp His Lys Glu Pro
         35                  40                  45

Ser Asp Lys Pro Gln Lys Ala Val Gln Pro Lys His Glu Val Gly Thr
     50                  55                  60

Arg Arg Gly Cys Arg Arg Tyr Arg Trp Glu Leu Lys Asp Ser Asn Lys
 65                  70                  75                  80

Glu Phe Trp Leu Leu Gly His Ala Glu Ile Lys Ile Arg Ser Leu Gly
                 85                  90                  95

Cys Leu Ile Ala Ala Met Ile Leu Leu Ser Ser Leu Thr Val His Pro
            100                 105                 110

Ile Leu Arg Leu Ile Ile Thr Met Glu Ile Ser Phe Phe Ser Phe Phe
        115                 120                 125

Ile Leu Leu Tyr Ser Phe Ala Ile His Arg Tyr Ile Pro Phe Ile Leu
    130                 135                 140

Trp Pro Ile Ser Asp Leu Phe Asn Asp Leu Ile Ala Cys Ala Phe Leu
145                 150                 155                 160

Val Gly Ala Val Val Phe Ala Val Arg Ser Arg Arg Ser Met Asn Leu
                165                 170                 175

His Tyr Leu Leu Ala Val Ile Leu Ile Gly Ala Ala Gly Val Phe Ala
            180                 185                 190

Phe Ile Asp Val Cys Leu Gln Arg Asn His Phe Arg Gly Lys Lys Ala
        195                 200                 205

Lys Lys His Met Leu Val Pro Pro Pro Gly Lys Glu Lys Gly Pro Gln
    210                 215                 220

Gln Gly Lys Gly Pro Glu Pro Ala Lys Pro Pro Glu Pro Gly Lys Pro
225                 230                 235                 240

Pro Gly Pro Ala Lys Gly Lys Lys 
                245



<210> 2701
<211> 285
<212> PRT
<213> Homo sapiens

<400> 2701
Met Asp Asp Ser Thr Glu Arg Glu Gln Ser Arg Leu Thr Ser Cys Leu
  1               5                  10                  15

Lys Lys Arg Glu Glu Met Lys Leu Lys Glu Cys Val Ser Ile Leu Pro
             20                  25                  30

Arg Lys Glu Ser Pro Ser Val Arg Ser Ser Lys Asp Gly Lys Leu Leu
         35                  40                  45

Ala Ala Thr Leu Leu Leu Ala Leu Leu Ser Cys Cys Leu Thr Val Val
     50                  55                  60

Ser Phe Tyr Gln Val Ala Ala Leu Gln Gly Asp Leu Ala Ser Leu Arg
 65                  70                  75                  80

Ala Glu Leu Gln Gly His His Ala Glu Lys Leu Pro Ala Gly Ala Gly
                 85                  90                  95

Ala Pro Lys Ala Gly Leu Glu Glu Ala Pro Ala Val Thr Ala Gly Leu
            100                 105                 110

Lys Ile Phe Glu Pro Pro Ala Pro Gly Glu Gly Asn Ser Ser Gln Asn
        115                 120                 125

Ser Arg Asn Lys Arg Ala Val Gln Gly Pro Glu Glu Thr Val Thr Gln
    130                 135                 140

Asp Cys Leu Gln Leu Ile Ala Asp Ser Glu Thr Pro Thr Ile Gln Lys
145                 150                 155                 160

Gly Ser Tyr Thr Phe Val Pro Trp Leu Leu Ser Phe Lys Arg Gly Ser
                165                 170                 175

Ala Leu Glu Glu Lys Glu Asn Lys Ile Leu Val Lys Glu Thr Gly Tyr
            180                 185                 190

Phe Phe Ile Tyr Gly Gln Val Leu Tyr Thr Asp Lys Thr Tyr Ala Met
        195                 200                 205

Gly His Leu Ile Gln Arg Lys Lys Val His Val Phe Gly Asp Glu Leu
    210                 215                 220

Ser Leu Val Thr Leu Phe Arg Cys Ile Gln Asn Met Pro Glu Thr Leu
225                 230                 235                 240

Pro Asn Asn Ser Cys Tyr Ser Ala Gly Ile Ala Lys Leu Glu Glu Gly
                245                 250                 255

Asp Glu Leu Gln Leu Ala Ile Pro Arg Glu Asn Ala Gln Ile Ser Leu
            260                 265                 270

Asp Gly Asp Val Thr Phe Phe Gly Ala Leu Lys Leu Leu 
        275                 280                 285



<210> 2702
<211> 212
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (196)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (212)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2702
Met Asp Ala Leu Lys Pro Pro Cys Leu Trp Arg Asn His Glu Arg Gly
  1               5                  10                  15

Lys Lys Asp Arg Asp Ser Cys Gly Arg Lys Asn Ser Glu Pro Gly Ser
             20                  25                  30

Pro His Ser Leu Glu Ala Leu Arg Asp Ala Ala Pro Ser Gln Gly Leu
         35                  40                  45

Asn Phe Leu Leu Leu Phe Thr Lys Met Leu Phe Ile Phe Asn Phe Leu
     50                  55                  60

Phe Ser Pro Leu Pro Thr Pro Ala Leu Ile Cys Ile Leu Thr Phe Gly
 65                  70                  75                  80

Ala Ala Ile Phe Leu Trp Leu Ile Thr Arg Pro Gln Pro Val Leu Pro
                 85                  90                  95

Leu Leu Asp Leu Asn Asn Gln Ser Val Gly Ile Glu Gly Gly Ala Arg
            100                 105                 110

Lys Gly Val Ser Gln Lys Asn Asn Asp Leu Thr Ser Cys Cys Phe Ser
        115                 120                 125

Asp Ala Lys Thr Met Tyr Glu Val Phe Gln Arg Gly Leu Ala Val Ser
    130                 135                 140

Asp Asn Gly Pro Cys Leu Gly Tyr Arg Lys Pro Asn Gln Pro Tyr Arg
145                 150                 155                 160

Trp Leu Ser Tyr Lys Gln Val Ser Asp Xaa Ala Xaa Tyr Leu Gly Ser
                165                 170                 175

Xaa Leu Leu His Lys Gly Tyr Asn His His Gln Thr Ser Leu Ser Ala
            180                 185                 190

Ser Leu Leu Xaa Ile Gly Gln Ser Gly Ser Ser Pro Asn Trp Leu Val
        195                 200                 205

Thr Thr Leu Xaa 
    210



<210> 2703
<211> 310
<212> PRT
<213> Homo sapiens

<400> 2703
Met Val Tyr Lys Thr Leu Phe Ala Leu Cys Ile Leu Thr Ala Gly Trp
  1               5                  10                  15

Arg Val Gln Ser Leu Pro Thr Ser Ala Pro Leu Ser Val Ser Leu Pro
             20                  25                  30

Thr Asn Ile Val Pro Pro Thr Thr Ile Trp Thr Ser Ser Pro Gln Asn
         35                  40                  45

Thr Asp Ala Asp Thr Ala Ser Pro Ser Asn Gly Thr His Asn Asn Ser
     50                  55                  60

Val Leu Pro Val Thr Ala Ser Ala Pro Thr Ser Leu Leu Pro Lys Asn
 65                  70                  75                  80

Ile Ser Ile Glu Ser Arg Glu Glu Glu Ile Thr Ser Pro Gly Ser Asn
                 85                  90                  95

Trp Glu Gly Thr Asn Thr Asp Pro Ser Pro Ser Gly Phe Ser Ser Thr
            100                 105                 110

Ser Gly Gly Val His Leu Thr Thr Thr Leu Glu Glu His Ser Ser Gly
        115                 120                 125

Thr Pro Glu Ala Gly Val Ala Ala Thr Leu Ser Gln Ser Ala Ala Glu
    130                 135                 140

Pro Pro Thr Leu Ile Ser Pro Gln Ala Pro Ala Ser Ser Pro Ser Ser
145                 150                 155                 160

Leu Ser Thr Ser Pro Pro Glu Val Phe Ser Ala Ser Val Thr Thr Asn
                165                 170                 175

His Ser Ser Thr Val Thr Ser Thr Gln Pro Thr Gly Ala Pro Thr Ala
            180                 185                 190

Pro Glu Ser Pro Thr Glu Glu Ser Ser Ser Asp His Thr Pro Thr Ser
        195                 200                 205

His Ala Thr Ala Glu Pro Val Pro Gln Glu Lys Thr Pro Pro Thr Thr
    210                 215                 220

Val Ser Gly Lys Val Met Cys Glu Leu Ile Asp Met Glu Thr Thr Thr
225                 230                 235                 240

Thr Phe Pro Arg Val Ile Met Gln Glu Val Glu His Ala Leu Ser Ser
                245                 250                 255

Gly Ser Ile Ala Ala Ile Thr Val Thr Val Ile Ala Val Val Leu Leu
            260                 265                 270

Val Phe Gly Val Ala Ala Tyr Leu Lys Ile Arg His Ser Ser Tyr Gly
        275                 280                 285

Arg Leu Leu Asp Asp His Asp Tyr Gly Ser Trp Gly Asn Tyr Asn Asn
    290                 295                 300

Pro Leu Tyr Asp Asp Ser 
305                 310



<210> 2704
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (131)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (133)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2704
Met Lys Leu Leu Ser Leu Val Ala Val Val Gly Cys Leu Leu Val Pro
  1               5                  10                  15

Pro Ala Glu Ala Asn Lys Ser Ser Glu Asp Ile Arg Cys Lys Cys Ile
             20                  25                  30

Cys Pro Pro Tyr Arg Asn Ile Ser Gly His Ile Tyr Asn Gln Asn Val
         35                  40                  45

Ser Gln Lys Asp Cys Asn Cys Leu His Val Val Glu Pro Met Pro Val
     50                  55                  60

Pro Gly His Asp Val Glu Ala Tyr Cys Leu Leu Cys Glu Cys Arg Tyr
 65                  70                  75                  80

Glu Glu Arg Ser Thr Thr Thr Ile Lys Val Ile Ile Val Ile Tyr Leu
                 85                  90                  95

Ser Val Val Gly Ala Leu Leu Leu Tyr Met Ala Phe Leu Met Leu Val
            100                 105                 110

Asp Pro Leu Ile Arg Lys Pro Asp Ala Tyr Thr Glu Gln Leu His Asn
        115                 120                 125

Glu Glu Xaa Asn Xaa Asp Ala Arg Ser Met Ala Ser Ser 
    130                 135                 140



<210> 2705
<211> 567
<212> PRT
<213> Homo sapiens

<400> 2705
Met Leu Val Thr Ser Lys Met Ala Ala Pro Glu Ala Pro Ala Thr Ser
  1               5                  10                  15

Ala Gln Ser Gln Thr Gly Ser Pro Ala Gln Glu Ala Ala Thr Glu Gly
             20                  25                  30

Pro Ser Ser Ala Cys Ala Phe Ser Gln Ala Pro Cys Ala Arg Glu Val
         35                  40                  45

Asp Ala Asn Arg Pro Ser Thr Ala Phe Leu Gly Gln Asn Asp Val Phe
     50                  55                  60

Asp Phe Thr Gln Pro Ala Gly Val Ser Gly Met Ala Phe Pro Arg Pro
 65                  70                  75                  80

Lys Arg Pro Ala Pro Ala Gln Glu Ala Ala Thr Glu Gly Pro Ser Ala
                 85                  90                  95

Ala Ser Gly Val Pro Gln Thr Gly Pro Gly Arg Glu Val Ala Ala Thr
            100                 105                 110

Arg Pro Lys Thr Thr Lys Ser Gly Lys Ala Leu Ala Lys Thr Arg Trp
        115                 120                 125

Val Glu Pro Gln Asn Val Val Ala Ala Ala Ala Ala Lys Ala Lys Met
    130                 135                 140

Ala Thr Ser Ile Pro Glu Pro Glu Gly Ala Ala Ala Ala Thr Ala Gln
145                 150                 155                 160

His Ser Ala Glu Pro Trp Ala Arg Met Gly Gly Lys Arg Thr Lys Lys
                165                 170                 175

Ser Lys His Leu Asp Asp Glu Tyr Glu Ser Ser Glu Glu Glu Arg Glu
            180                 185                 190

Thr Pro Ala Val Pro Pro Thr Trp Arg Ala Ser Gln Pro Ser Leu Thr
        195                 200                 205

Val Arg Ala Gln Leu Ala Pro Arg Pro Pro Met Ala Pro Arg Ser Gln
    210                 215                 220

Ile Pro Ser Arg His Val Leu Cys Leu Pro Pro Arg Asn Val Thr Leu
225                 230                 235                 240

Leu Gln Glu Arg Ala Asn Lys Leu Val Lys Tyr Leu Met Ile Lys Asp
                245                 250                 255

Tyr Lys Lys Ile Pro Ile Lys Arg Ala Asp Met Leu Lys Asp Val Ile
            260                 265                 270

Arg Glu Tyr Asp Glu His Phe Pro Glu Ile Ile Glu Arg Ala Thr Tyr
        275                 280                 285

Thr Leu Glu Lys Lys Phe Gly Ile His Leu Lys Glu Ile Asp Lys Glu
    290                 295                 300

Glu His Leu Tyr Ile Leu Val Cys Thr Arg Asp Ser Ser Ala Arg Leu
305                 310                 315                 320

Leu Gly Lys Thr Lys Asp Thr Pro Arg Leu Ser Leu Leu Leu Val Ile
                325                 330                 335

Leu Gly Val Ile Phe Met Asn Gly Asn Arg Ala Ser Glu Ala Val Leu
            340                 345                 350

Trp Glu Ala Leu Arg Lys Met Gly Leu Arg Pro Gly Val Arg His Pro
        355                 360                 365

Phe Leu Gly Asp Leu Arg Lys Leu Ile Thr Asp Asp Phe Val Lys Gln
    370                 375                 380

Lys Tyr Leu Glu Tyr Lys Lys Ile Pro Asn Ser Asn Pro Pro Glu Tyr
385                 390                 395                 400

Glu Phe Leu Trp Gly Leu Arg Ala Arg His Glu Thr Ser Lys Met Arg
                405                 410                 415

Val Leu Arg Phe Ile Ala Gln Asn Gln Asn Arg Asp Pro Arg Glu Trp
            420                 425                 430

Lys Ala His Phe Leu Glu Ala Val Asp Asp Ala Phe Lys Thr Met Asp
        435                 440                 445

Val Asp Met Ala Glu Glu His Ala Arg Ala Gln Met Arg Ala Gln Met
    450                 455                 460

Asn Ile Gly Asp Glu Ala Leu Ile Gly Arg Trp Ser Trp Asp Asp Ile
465                 470                 475                 480

Gln Val Glu Leu Leu Thr Trp Asp Glu Asp Gly Asp Phe Gly Asp Ala
                485                 490                 495

Trp Ala Arg Ile Pro Phe Ala Phe Trp Ala Arg Tyr His Gln Tyr Ile
            500                 505                 510

Leu Asn Ser Asn Arg Ala Asn Arg Arg Ala Thr Trp Arg Ala Gly Val
        515                 520                 525

Ser Ser Gly Thr Asn Gly Gly Ala Ser Thr Ser Val Leu Asp Gly Pro
    530                 535                 540

Ser Thr Ser Ser Thr Ile Arg Thr Arg Asn Ala Ala Arg Ala Gly Ala
545                 550                 555                 560

Ser Phe Phe Ser Trp Ile Gln 
                565



<210> 2706
<211> 374
<212> PRT
<213> Homo sapiens

<400> 2706
Met Val Leu Trp Glu Ser Pro Arg Gln Cys Ser Ser Trp Thr Leu Cys
  1               5                  10                  15

Glu Gly Phe Cys Trp Leu Leu Leu Leu Pro Val Met Leu Leu Ile Val
             20                  25                  30

Ala Arg Pro Val Lys Leu Ala Ala Phe Pro Thr Ser Leu Ser Asp Cys
         35                  40                  45

Gln Thr Pro Thr Gly Trp Asn Cys Ser Gly Tyr Asp Asp Arg Glu Asn
     50                  55                  60

Asp Leu Phe Leu Cys Asp Thr Asn Thr Cys Lys Phe Asp Gly Glu Cys
 65                  70                  75                  80

Leu Arg Ile Gly Asp Thr Val Thr Cys Val Cys Gln Phe Lys Cys Asn
                 85                  90                  95

Asn Asp Tyr Val Pro Val Cys Gly Ser Asn Gly Glu Ser Tyr Gln Asn
            100                 105                 110

Glu Cys Tyr Leu Arg Gln Ala Ala Cys Lys Gln Gln Ser Glu Ile Leu
        115                 120                 125

Val Val Ser Glu Gly Ser Cys Ala Thr Asp Ala Gly Ser Gly Ser Gly
    130                 135                 140

Asp Gly Val His Glu Gly Ser Gly Glu Thr Ser Gln Lys Glu Thr Ser
145                 150                 155                 160

Thr Cys Asp Ile Cys Gln Phe Gly Ala Glu Cys Asp Glu Asp Ala Glu
                165                 170                 175

Asp Val Trp Cys Val Cys Asn Ile Asp Cys Ser Gln Thr Asn Phe Asn
            180                 185                 190

Pro Leu Cys Ala Ser Asp Gly Lys Ser Tyr Asp Asn Ala Cys Gln Ile
        195                 200                 205

Lys Glu Ala Ser Cys Gln Lys Gln Glu Lys Ile Glu Val Met Ser Leu
    210                 215                 220

Gly Arg Cys Gln Asp Asn Thr Thr Thr Thr Thr Lys Ser Glu Asp Gly
225                 230                 235                 240

His Tyr Ala Arg Thr Asp Tyr Ala Glu Asn Ala Asn Lys Leu Glu Glu
                245                 250                 255

Ser Ala Arg Glu His His Ile Pro Cys Pro Glu His Tyr Asn Gly Phe
            260                 265                 270

Cys Met His Gly Lys Cys Glu His Ser Ile Asn Met Gln Glu Pro Ser
        275                 280                 285

Cys Arg Cys Asp Ala Gly Tyr Thr Gly Gln His Cys Glu Lys Lys Asp
    290                 295                 300

Tyr Ser Val Leu Tyr Val Val Pro Gly Pro Val Arg Phe Gln Tyr Val
305                 310                 315                 320

Leu Ile Ala Ala Val Ile Gly Thr Ile Gln Ile Ala Val Ile Cys Val
                325                 330                 335

Val Val Leu Cys Ile Thr Arg Lys Cys Pro Arg Ser Asn Arg Ile His
            340                 345                 350

Arg Gln Lys Gln Asn Thr Gly His Tyr Ser Ser Asp Asn Thr Thr Arg
        355                 360                 365

Ala Ser Thr Arg Leu Ile 
    370



<210> 2707
<211> 128
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (124)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2707
Met Ser Ile Cys Trp Val Arg Ser Pro Val Val His Ser Val Leu Val
  1               5                  10                  15

Met Gly Tyr Gly Gly Leu Thr Ser Leu Phe Asn Leu Val Val Leu Ala
             20                  25                  30

Trp Ala Leu Trp Thr Leu Arg Arg Leu Arg Glu Arg Ala Asp Ala Pro
         35                  40                  45

Ser Val Arg Ala Cys His Asp Thr Val Thr Val Leu Gly Leu Thr Val
     50                  55                  60

Leu Leu Gly Thr Thr Trp Ala Leu Ala Phe Phe Ser Phe Gly Val Phe
 65                  70                  75                  80

Leu Leu Pro Gln Leu Phe Leu Phe Thr Ile Leu Asn Ser Leu Tyr Gly
                 85                  90                  95

Phe Phe Leu Phe Leu Trp Phe Cys Ser Gln Arg Cys Arg Ser Glu Ala
            100                 105                 110

Glu Ala Lys Ala Gln Ile Glu Ala Phe Ser Ser Xaa Gln Thr Thr Gln
        115                 120                 125






<210> 2708
<211> 465
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (220)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2708
Met Glu Glu Glu Asp Glu Glu Ala Arg Ala Leu Leu Ala Gly Gly Pro
  1               5                  10                  15

Asp Glu Ala Asp Arg Gly Ala Pro Ala Ala Pro Gly Ala Leu Pro Ala
             20                  25                  30

Leu Cys Asp Pro Ser Arg Leu Ala His Arg Leu Leu Val Leu Leu Leu
         35                  40                  45

Met Cys Phe Leu Gly Phe Gly Ser Tyr Phe Cys Tyr Asp Asn Pro Ala
     50                  55                  60

Ala Leu Gln Thr Gln Val Lys Arg Asp Met Gln Val Asn Thr Thr Lys
 65                  70                  75                  80

Phe Met Leu Leu Tyr Ala Trp Tyr Ser Trp Pro Asn Val Val Leu Cys
                 85                  90                  95

Phe Phe Gly Gly Phe Leu Ile Xaa Arg Xaa Phe Gly Ile Xaa Trp Gly
            100                 105                 110

Thr Ile Ile Phe Ser Cys Phe Val Cys Ile Gly Gln Val Val Phe Ala
        115                 120                 125

Leu Gly Gly Ile Phe Asn Ala Phe Trp Leu Met Glu Phe Gly Arg Phe
    130                 135                 140

Val Phe Gly Ile Gly Gly Glu Ser Leu Ala Val Ala Gln Asn Thr Tyr
145                 150                 155                 160

Ala Val Ser Trp Phe Lys Gly Lys Glu Leu Asn Leu Val Phe Gly Leu
                165                 170                 175

Gln Leu Ser Met Ala Arg Ile Gly Ser Thr Val Asn Met Asn Leu Met
            180                 185                 190

Gly Trp Leu Tyr Ser Lys Ile Glu Ala Leu Leu Gly Ser Ala Gly His
        195                 200                 205

Thr Thr Leu Gly Ile Thr Leu Met Ile Gly Gly Xaa Thr Cys Ile Leu
    210                 215                 220

Ser Leu Ile Cys Ala Leu Ala Leu Ala Tyr Leu Asp Gln Arg Ala Glu
225                 230                 235                 240

Arg Ile Leu His Lys Glu Gln Gly Lys Thr Gly Glu Val Ile Lys Leu
                245                 250                 255

Thr Asp Val Lys Asp Phe Ser Leu Pro Leu Trp Leu Ile Phe Ile Ile
            260                 265                 270

Cys Val Cys Tyr Tyr Val Ala Val Phe Pro Phe Ile Gly Leu Gly Lys
        275                 280                 285

Val Phe Phe Thr Glu Lys Phe Gly Phe Ser Ser Gln Ala Ala Ser Ala
    290                 295                 300

Ile Asn Ser Val Val Tyr Val Ile Ser Ala Pro Met Ser Pro Val Phe
305                 310                 315                 320

Gly Leu Leu Val Asp Lys Thr Gly Lys Asn Ile Ile Trp Val Leu Cys
                325                 330                 335

Ala Val Ala Ala Thr Leu Val Ser His Met Met Leu Ala Phe Thr Met
            340                 345                 350

Trp Asn Pro Trp Ile Ala Met Cys Leu Leu Gly Leu Ser Tyr Ser Leu
        355                 360                 365

Leu Ala Cys Ala Leu Trp Pro Met Val Ala Phe Val Val Pro Glu His
    370                 375                 380

Gln Leu Gly Thr Ala Tyr Gly Phe Met Gln Ser Ile Gln Asn Leu Gly
385                 390                 395                 400

Leu Ala Ile Ile Ser Ile Ile Ala Gly Met Ile Leu Asp Ser Arg Gly
                405                 410                 415

Tyr Leu Phe Leu Glu Val Phe Phe Ile Ala Cys Val Ser Leu Ser Leu
            420                 425                 430

Leu Ser Val Val Leu Leu Tyr Leu Val Asn Arg Ala Gln Gly Gly Asn
        435                 440                 445

Leu Asn Tyr Ser Ala Arg Gln Arg Glu Glu Ile Lys Phe Ser His Thr
    450                 455                 460

Glu 
465



<210> 2709
<211> 372
<212> PRT
<213> Homo sapiens

<400> 2709
Met Ser Asn Asn Asn Leu Ser Asn Leu Pro Gln Gly Ile Phe Asp Asp
  1               5                  10                  15

Leu Asp Asn Ile Thr Gln Leu Ile Leu Arg Asn Asn Pro Trp Tyr Cys
             20                  25                  30

Gly Cys Lys Met Lys Trp Val Arg Asp Trp Leu Gln Ser Leu Pro Val
         35                  40                  45

Lys Val Asn Val Arg Gly Leu Met Cys Gln Ala Pro Glu Lys Val Arg
     50                  55                  60

Gly Met Ala Ile Lys Asp Leu Asn Ala Glu Leu Phe Asp Cys Lys Asp
 65                  70                  75                  80

Ser Gly Ile Val Ser Thr Ile Gln Ile Thr Thr Ala Ile Pro Asn Thr
                 85                  90                  95

Val Tyr Pro Ala Gln Gly Gln Trp Pro Ala Pro Val Thr Lys Gln Pro
            100                 105                 110

Asp Ile Lys Asn Pro Lys Leu Thr Lys Asp Gln Gln Thr Thr Gly Ser
        115                 120                 125

Pro Ser Arg Lys Thr Ile Thr Ile Thr Val Lys Ser Val Thr Ser Asp
    130                 135                 140

Thr Ile His Ile Ser Trp Lys Leu Ala Leu Pro Met Thr Ala Leu Arg
145                 150                 155                 160

Leu Ser Trp Leu Lys Leu Gly His Ser Pro Ala Phe Gly Ser Ile Thr
                165                 170                 175

Glu Thr Ile Val Thr Gly Glu Arg Ser Glu Tyr Leu Val Thr Ala Leu
            180                 185                 190

Glu Pro Asp Ser Pro Tyr Lys Val Cys Met Val Pro Met Glu Thr Ser
        195                 200                 205

Asn Leu Tyr Leu Phe Asp Glu Thr Pro Val Cys Ile Glu Thr Glu Thr
    210                 215                 220

Ala Pro Leu Arg Met Tyr Asn Pro Thr Thr Thr Leu Asn Arg Glu Gln
225                 230                 235                 240

Glu Lys Glu Pro Tyr Lys Asn Pro Asn Leu Pro Leu Ala Ala Ile Ile
                245                 250                 255

Gly Gly Ala Val Ala Leu Val Thr Ile Ala Leu Leu Ala Leu Val Cys
            260                 265                 270

Trp Tyr Val His Arg Asn Gly Ser Leu Phe Ser Arg Asn Cys Ala Tyr
        275                 280                 285

Ser Lys Gly Arg Arg Arg Lys Asp Asp Tyr Ala Glu Ala Gly Thr Lys
    290                 295                 300

Lys Asp Asn Ser Ile Leu Glu Ile Arg Glu Thr Ser Phe Gln Met Leu
305                 310                 315                 320

Pro Ile Ser Asn Glu Pro Ile Ser Lys Glu Glu Phe Val Ile His Thr
                325                 330                 335

Ile Phe Pro Pro Asn Gly Met Asn Leu Tyr Lys Asn Asn His Ser Glu
            340                 345                 350

Ser Ser Ser Asn Arg Ser Tyr Arg Asp Ser Gly Ile Pro Asp Ser Asp
        355                 360                 365

His Ser His Ser 
    370



<210> 2710
<211> 530
<212> PRT
<213> Homo sapiens

<400> 2710
Met Ala Lys Gly Glu Gly Ala Glu Ser Gly Ser Ala Ala Gly Leu Leu
  1               5                  10                  15

Pro Thr Ser Ile Leu Gln Ser Thr Glu Arg Pro Ala Gln Val Lys Lys
             20                  25                  30

Glu Pro Lys Lys Lys Lys Gln Gln Leu Ser Val Cys Asn Lys Leu Cys
         35                  40                  45

Tyr Ala Leu Gly Gly Ala Pro Tyr Gln Val Thr Gly Cys Ala Leu Gly
     50                  55                  60

Phe Phe Leu Gln Ile Tyr Leu Leu Asp Val Ala Gln Val Gly Pro Phe
 65                  70                  75                  80

Ser Ala Ser Ile Ile Leu Phe Val Gly Arg Ala Trp Asp Ala Ile Thr
                 85                  90                  95

Asp Pro Leu Val Gly Leu Cys Ile Ser Lys Ser Pro Trp Thr Cys Leu
            100                 105                 110

Gly Arg Leu Met Pro Trp Ile Ile Phe Ser Thr Pro Leu Ala Val Ile
        115                 120                 125

Ala Tyr Phe Leu Ile Trp Phe Val Pro Asp Phe Pro His Gly Gln Thr
    130                 135                 140

Tyr Trp Tyr Leu Leu Phe Tyr Cys Leu Phe Glu Thr Met Val Thr Cys
145                 150                 155                 160

Phe His Val Pro Tyr Ser Ala Leu Thr Met Phe Ile Ser Thr Glu Gln
                165                 170                 175

Thr Glu Arg Asp Ser Ala Thr Ala Tyr Arg Met Thr Val Glu Val Leu
            180                 185                 190

Gly Thr Val Leu Gly Thr Ala Ile Gln Gly Gln Ile Val Gly Gln Ala
        195                 200                 205

Asp Thr Pro Cys Phe Gln Asp Leu Asn Ser Ser Thr Val Ala Ser Gln
    210                 215                 220

Ser Ala Asn His Thr His Gly Thr Thr Ser His Arg Glu Thr Gln Lys
225                 230                 235                 240

Ala Tyr Leu Leu Ala Ala Gly Val Ile Val Cys Ile Tyr Ile Ile Cys
                245                 250                 255

Ala Val Ile Leu Ile Leu Gly Val Arg Glu Gln Arg Glu Pro Tyr Glu
            260                 265                 270

Ala Gln Gln Ser Glu Pro Ile Ala Tyr Phe Arg Gly Leu Arg Leu Val
        275                 280                 285

Met Ser His Gly Pro Tyr Ile Lys Leu Ile Thr Gly Phe Leu Phe Thr
    290                 295                 300

Ser Leu Ala Phe Met Leu Val Glu Gly Asn Phe Val Leu Phe Cys Thr
305                 310                 315                 320

Tyr Thr Leu Gly Phe Arg Asn Glu Phe Gln Asn Leu Leu Leu Ala Ile
                325                 330                 335

Met Leu Ser Ala Thr Leu Thr Ile Pro Ile Trp Gln Trp Phe Leu Thr
            340                 345                 350

Arg Phe Gly Lys Lys Thr Ala Val Tyr Val Gly Ile Ser Ser Ala Val
        355                 360                 365

Pro Phe Leu Ile Leu Val Ala Leu Met Glu Ser Asn Leu Ile Ile Thr
    370                 375                 380

Tyr Ala Val Ala Val Ala Ala Gly Ile Ser Val Ala Ala Ala Phe Leu
385                 390                 395                 400

Leu Pro Trp Ser Met Leu Pro Asp Val Ile Asp Asp Phe His Leu Lys
                405                 410                 415

Gln Pro His Phe His Gly Thr Glu Pro Ile Phe Phe Ser Phe Tyr Val
            420                 425                 430

Phe Phe Thr Lys Phe Ala Ser Gly Val Ser Leu Gly Ile Ser Thr Leu
        435                 440                 445

Ser Leu Asp Phe Ala Gly Tyr Gln Thr Arg Gly Cys Ser Gln Pro Glu
    450                 455                 460

Arg Val Lys Phe Thr Leu Asn Met Leu Val Thr Met Ala Pro Ile Val
465                 470                 475                 480

Leu Ile Leu Leu Gly Leu Leu Leu Phe Lys Met Tyr Pro Ile Asp Glu
                485                 490                 495

Glu Arg Arg Arg Gln Asn Lys Lys Ala Leu Gln Ala Leu Arg Asp Glu
            500                 505                 510

Ala Ser Ser Ser Gly Cys Ser Glu Thr Asp Ser Thr Glu Leu Ala Ser
        515                 520                 525

Ile Leu 
    530



<210> 2711
<211> 296
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (216)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (248)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (265)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2711
Met Ala Gly Ile Leu Ala Trp Phe Trp Asn Glu Arg Phe Trp Leu Pro
  1               5                  10                  15

His Asn Val Thr Trp Ala Asp Leu Lys Asn Thr Glu Glu Ala Thr Phe
             20                  25                  30

Pro Gln Ala Glu Asp Leu Tyr Leu Ala Phe Pro Leu Ala Phe Cys Ile
         35                  40                  45

Phe Met Val Arg Leu Ile Phe Glu Arg Phe Val Ala Lys Pro Cys Ala
     50                  55                  60

Ile Ala Leu Asn Ile Gln Ala Asn Gly Pro Gln Ile Ala Pro Pro Asn
 65                  70                  75                  80

Ala Ile Leu Glu Lys Val Phe Thr Ala Ile Thr Lys His Pro Asp Glu
                 85                  90                  95

Lys Arg Leu Glu Gly Leu Ser Lys Gln Leu Asp Trp Asp Val Arg Ser
            100                 105                 110

Ile Gln Arg Trp Phe Arg Gln Arg Arg Asn Gln Glu Lys Pro Ser Thr
        115                 120                 125

Leu Thr Arg Phe Cys Glu Ser Met Trp Arg Phe Ser Phe Tyr Leu Tyr
    130                 135                 140

Val Phe Thr Tyr Gly Val Arg Phe Leu Lys Lys Thr Pro Trp Leu Trp
145                 150                 155                 160

Asn Thr Arg His Cys Trp Tyr Asn Tyr Pro Tyr Gln Pro Leu Thr Thr
                165                 170                 175

Asp Leu His Tyr Tyr Tyr Ile Leu Glu Leu Ser Phe Tyr Trp Ser Leu
            180                 185                 190

Met Phe Ser Gln Phe Thr Asp Ile Lys Arg Lys Asp Phe Gly Ile Met
        195                 200                 205

Phe Leu His His Leu Val Ser Xaa Phe Leu Ile Thr Phe Ser Tyr Val
    210                 215                 220

Asn Asn Met Ala Arg Val Gly Thr Leu Val Leu Cys Leu His Asp Ser
225                 230                 235                 240

Ala Asp Ala Leu Leu Glu Ala Xaa Lys Met Ala Asn Tyr Ala Lys Phe
                245                 250                 255

Gln Lys Met Cys Asp Leu Leu Phe Xaa Met Phe Ala Val Val Phe Ile
            260                 265                 270

Thr Thr Arg Leu Gly Ile Phe Pro Leu Trp Pro Leu Leu Trp Cys Pro
        275                 280                 285

Asp Gly Lys Cys Ser Val Gly Leu 
    290                 295



<210> 2712
<211> 223
<212> PRT
<213> Homo sapiens

<400> 2712
Met Thr Trp Arg His His Val Arg Leu Leu Phe Thr Val Ser Leu Ala
  1               5                  10                  15

Leu Gln Ile Ile Asn Leu Gly Asn Ser Tyr Gln Arg Glu Lys His Asn
             20                  25                  30

Gly Gly Arg Glu Glu Val Thr Lys Val Ala Thr Gln Lys His Arg Gln
         35                  40                  45

Ser Pro Leu Asn Trp Thr Ser Ser His Phe Gly Glu Val Thr Gly Ser
     50                  55                  60

Ala Glu Gly Trp Gly Pro Glu Glu Pro Leu Pro Tyr Ser Arg Ala Phe
 65                  70                  75                  80

Gly Glu Gly Ala Ser Ala Arg Pro Arg Cys Cys Arg Asn Gly Gly Thr
                 85                  90                  95

Cys Val Leu Gly Ser Phe Cys Val Cys Pro Ala His Phe Thr Gly Arg
            100                 105                 110

Tyr Cys Glu His Asp Gln Arg Arg Ser Glu Cys Gly Ala Leu Glu His
        115                 120                 125

Gly Ala Trp Thr Leu Arg Ala Cys His Leu Cys Arg Cys Ile Phe Gly
    130                 135                 140

Ala Leu His Cys Leu Pro Leu Gln Thr Pro Asp Arg Cys Asp Pro Lys
145                 150                 155                 160

Asp Phe Leu Ala Ser His Ala His Gly Pro Ser Ala Gly Gly Ala Pro
                165                 170                 175

Ser Leu Leu Leu Leu Leu Pro Cys Ala Leu Leu His Arg Leu Leu Arg
            180                 185                 190

Pro Asp Ala Pro Ala His Pro Arg Ser Leu Val Pro Ser Val Leu Gln
        195                 200                 205

Arg Glu Arg Arg Pro Cys Gly Arg Pro Gly Leu Gly His Arg Leu 
    210                 215                 220



<210> 2713
<211> 206
<212> PRT
<213> Homo sapiens

<400> 2713
Met Leu Leu Gln Ser Gln Thr Met Gly Val Ser His Ser Phe Thr Pro
  1               5                  10                  15

Lys Gly Ile Thr Ile Pro Gln Arg Glu Lys Pro Gly His Met Tyr Gln
             20                  25                  30

Asn Glu Asp Tyr Leu Gln Asn Gly Leu Pro Thr Glu Thr Thr Val Leu
         35                  40                  45

Gly Thr Val Gln Ile Leu Cys Cys Leu Leu Ile Ser Ser Leu Gly Ala
     50                  55                  60

Ile Leu Val Phe Ala Pro Tyr Pro Ser His Phe Asn Pro Ala Ile Ser
 65                  70                  75                  80

Thr Thr Leu Met Ser Gly Tyr Pro Phe Leu Gly Ala Leu Cys Phe Gly
                 85                  90                  95

Ile Thr Gly Ser Leu Ser Ile Ile Ser Gly Lys Gln Ser Thr Lys Pro
            100                 105                 110

Phe Asp Leu Ser Ser Leu Thr Ser Asn Ala Val Ser Ser Val Thr Ala
        115                 120                 125

Gly Ala Gly Leu Phe Leu Leu Ala Asp Ser Met Val Ala Leu Arg Thr
    130                 135                 140

Ala Ser Gln His Cys Gly Ser Glu Met Asp Tyr Leu Ser Ser Leu Pro
145                 150                 155                 160

Tyr Ser Glu Tyr Tyr Tyr Pro Ile Tyr Glu Ile Lys Asp Cys Leu Leu
                165                 170                 175

Thr Ser Val Ser Leu Thr Ser Ser Phe Ser Ser Thr Gln Ser Gln Asp
            180                 185                 190

His Ile Gln Gln Val Lys Lys Ser Ser Ser Arg Ser Trp Ile 
        195                 200                 205



<210> 2714
<211> 266
<212> PRT
<213> Homo sapiens

<400> 2714
Met Trp Trp Phe Gln Gln Gly Leu Ser Phe Leu Pro Ser Ala Leu Val
  1               5                  10                  15

Ile Trp Thr Ser Ala Ala Phe Ile Phe Ser Tyr Ile Thr Ala Val Thr
             20                  25                  30

Leu His His Ile Asp Pro Ala Leu Pro Tyr Ile Ser Asp Thr Gly Thr
         35                  40                  45

Val Ala Pro Glu Lys Cys Leu Phe Gly Ala Met Leu Asn Ile Ala Ala
     50                  55                  60

Val Leu Cys Ile Ala Thr Ile Tyr Val Arg Tyr Lys Gln Val His Ala
 65                  70                  75                  80

Leu Ser Pro Glu Glu Asn Val Ile Ile Lys Leu Asn Lys Ala Gly Leu
                 85                  90                  95

Val Leu Gly Ile Leu Ser Cys Leu Gly Leu Ser Ile Val Ala Asn Phe
            100                 105                 110

Gln Lys Thr Thr Leu Phe Ala Ala His Val Ser Gly Ala Val Leu Thr
        115                 120                 125

Phe Gly Met Gly Ser Leu Tyr Met Phe Val Gln Thr Ile Leu Ser Tyr
    130                 135                 140

Gln Met Gln Pro Lys Ile His Gly Lys Gln Val Phe Trp Ile Arg Leu
145                 150                 155                 160

Leu Leu Val Ile Trp Cys Gly Val Ser Ala Leu Ser Met Leu Thr Cys
                165                 170                 175

Ser Ser Val Leu His Ser Gly Asn Phe Gly Thr Asp Leu Glu Gln Lys
            180                 185                 190

Leu His Trp Asn Pro Glu Asp Lys Gly Tyr Val Leu His Met Ile Thr
        195                 200                 205

Thr Ala Ala Glu Trp Ser Met Ser Phe Ser Phe Phe Gly Phe Phe Leu
    210                 215                 220

Thr Tyr Ile Arg Asp Phe Gln Lys Ile Ser Leu Arg Val Glu Ala Asn
225                 230                 235                 240

Leu His Gly Leu Thr Leu Tyr Asp Thr Ala Pro Cys Pro Ile Asn Asn
                245                 250                 255

Glu Arg Thr Arg Leu Leu Ser Arg Asp Ile 
            260                 265



<210> 2715
<211> 219
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (177)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (191)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (192)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (198)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (210)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2715
Met Pro Gly Ser Ala Ser Lys Arg Arg Ile Pro Val Ser Gln Pro Gly
  1               5                  10                  15

Met Ala Asp Pro His Gln Leu Phe Asp Asp Thr Ser Ser Ala Gln Ser
             20                  25                  30

Arg Gly Tyr Gly Ala Gln Arg Ala Pro Gly Gly Leu Ser Tyr Pro Ala
         35                  40                  45

Ala Ser Pro Thr Pro His Ala Ala Phe Leu Ala Asp Pro Val Ser Asn
     50                  55                  60

Met Ala Met Ala Tyr Gly Ser Ser Leu Ala Ala Gln Gly Lys Glu Leu
 65                  70                  75                  80

Val Asp Lys Asn Ile Asp Arg Phe Ile Pro Ile Thr Lys Leu Lys Tyr
                 85                  90                  95

Tyr Phe Ala Val Asp Thr Met Tyr Val Gly Arg Lys Leu Gly Leu Leu
            100                 105                 110

Phe Phe Pro Tyr Leu His Gln Asp Trp Glu Val Gln Tyr Gln Gln Asp
        115                 120                 125

Thr Pro Val Ala Pro Arg Phe Asp Val Asn Ala Pro Asp Leu Tyr Ile
    130                 135                 140

Pro Ala Met Ala Phe Ile Thr Tyr Val Leu Val Ala Gly Leu Ala Leu
145                 150                 155                 160

Gly Thr Gln Asp Arg Phe Ser Pro Asp Leu Leu Gly Leu Gln Ala Ser
                165                 170                 175

Xaa Ala Leu Ala Trp Leu Thr Leu Glu Val Leu Ala Ile Leu Xaa Xaa
            180                 185                 190

Leu Tyr Xaa Gly Ser Xaa Gly Lys Asn Arg Asn Phe Thr Thr Ile Arg
        195                 200                 205

Thr Xaa Gly Gly Pro Phe Leu Gly Leu Thr Lys 
    210                 215



<210> 2716
<211> 285
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (250)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2716
Met Ser Ala Ala Val Arg Thr Glu Pro Leu Arg Gly Glu Pro Pro Leu
  1               5                  10                  15

Leu Val Arg Gly Asp Pro Tyr Ser Val Val Val Leu Leu Gln Gly Tyr
             20                  25                  30

Ala Glu Pro Glu Gly Val Asp Asp Ala Val Arg Ala Asp Gly Ser Val
         35                  40                  45

Thr Leu Val Leu Pro Gln Ala Trp Gly Ser Ala Thr Ser Leu Gln Glu
     50                  55                  60

Ser Pro Pro His Ser Gly Gly Ala Lys Thr Ala Leu Glu Glu Ala Ala
 65                  70                  75                  80

Arg Gly Pro Ile Leu Val Asp Thr Gly Gly Pro Trp Ala Arg Glu Ala
                 85                  90                  95

Leu Leu Gly Ala Leu Ala Gly Gln Gly Met Ala Pro Gly Asp Val Thr
            100                 105                 110

Leu Val Val Gly Thr His Gly His Ser Asp His Ile Gly Asn Leu Gly
        115                 120                 125

Leu Phe Pro Gly Ala Ala Leu Leu Val Ser His Asp Phe Cys Leu Pro
    130                 135                 140

Gly Gly Arg Tyr Leu Pro His Gly Leu Gly Glu Glu Arg Pro Leu Gln
145                 150                 155                 160

Leu Gly Pro Gly Leu Glu Val Trp Ala Thr Pro Gly His Gly Gly Gln
                165                 170                 175

Arg Asp Val Ser Val Val Val Ala Gly Thr Ala Leu Gly Thr Val Val
            180                 185                 190

Val Ala Gly Asp Val Phe Glu Arg Ser Gly Asp Glu Asp Ser Trp Gln
        195                 200                 205

Ala Leu Ser Glu Asp Pro Val Ala Gln Glu Arg Ser Arg Lys Arg Val
    210                 215                 220

Leu Asp Thr Ala Asp Val Val Val Pro Gly His Gly Ala Pro Phe Arg
225                 230                 235                 240

Gly Ser Glu Lys Pro Leu Ser His Gly Xaa Asp Val Gln Lys Thr Arg
                245                 250                 255

Gly Gln Cys Asp Arg Phe Gln Pro Pro Cys Lys Arg Pro Val Phe Gln
            260                 265                 270

Arg Gly Gln Ser Ser Leu Ser Leu Val Leu Gln Pro Asn 
        275                 280                 285



<210> 2717
<211> 248
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (185)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2717
Met Thr Ser Gln Pro Val Pro Asn Glu Thr Ile Ile Val Leu Pro Ser
  1               5                  10                  15

Asn Val Ile Asn Phe Ser Gln Ala Glu Lys Pro Glu Pro Thr Asn Gln
             20                  25                  30

Gly Gln Asp Ser Leu Lys Lys His Leu His Ala Glu Ile Lys Val Ile
         35                  40                  45

Gly Thr Ile Gln Ile Leu Cys Gly Met Met Val Leu Ser Leu Gly Ile
     50                  55                  60

Ile Leu Ala Ser Ala Ser Phe Ser Pro Asn Phe Thr Gln Val Thr Ser
 65                  70                  75                  80

Thr Leu Leu Asn Ser Ala Tyr Pro Phe Ile Gly Pro Phe Phe Phe Ile
                 85                  90                  95

Ile Ser Gly Ser Leu Ser Ile Ala Thr Glu Lys Arg Leu Thr Lys Leu
            100                 105                 110

Leu Val His Ser Ser Leu Val Gly Ser Ile Leu Ser Ala Leu Ser Ala
        115                 120                 125

Leu Val Gly Phe Ile Ile Leu Ser Val Lys Gln Ala Thr Leu Asn Pro
    130                 135                 140

Ala Ser Leu Gln Cys Glu Leu Asp Lys Asn Asn Ile Pro Thr Arg Ser
145                 150                 155                 160

Tyr Val Ser Tyr Phe Tyr His Asp Ser Leu Tyr Thr Thr Asp Cys Tyr
                165                 170                 175

Thr Ala Lys Ala Ser Leu Ala Gly Xaa Leu Ser Leu Met Leu Ile Cys
            180                 185                 190

Thr Leu Leu Glu Phe Cys Leu Ala Val Leu Thr Ala Val Leu Arg Trp
        195                 200                 205

Lys Gln Ala Tyr Ser Asp Phe Pro Gly Ser Val Leu Phe Leu Pro His
    210                 215                 220

Ser Tyr Ile Gly Asn Ser Gly Met Ser Ser Lys Met Thr His Asp Cys
225                 230                 235                 240

Gly Tyr Glu Glu Leu Leu Thr Ser 
                245



<210> 2718
<211> 323
<212> PRT
<213> Homo sapiens

<400> 2718
Met Asp Lys Ser Asp Leu Gly Gln Lys Arg Thr Ser Gly Ala Val Cys
  1               5                  10                  15

His Gln Asp Pro Arg Thr Cys Glu Glu Pro Ala Ser Ser Gly Ala His
             20                  25                  30

Ile Trp Pro Asp Asp Ile Thr Lys Trp Pro Ile Cys Thr Glu Gln Ala
         35                  40                  45

Arg Ser Asn His Thr Gly Phe Leu His Val Asp Cys Glu Ile Lys Gly
     50                  55                  60

Arg Pro Cys Cys Ile Gly Thr Lys Gly Ser Cys Glu Ile Thr Thr Arg
 65                  70                  75                  80

Glu Tyr Cys Glu Phe Met His Gly Tyr Phe His Glu Glu Ala Thr Leu
                 85                  90                  95

Cys Ser Gln Val His Cys Leu Asp Lys Val Cys Gly Leu Leu Pro Phe
            100                 105                 110

Leu Asn Pro Glu Val Pro Asp Gln Phe Tyr Arg Leu Trp Leu Ser Leu
        115                 120                 125

Phe Leu His Ala Gly Val Val His Cys Leu Val Ser Val Val Phe Gln
    130                 135                 140

Met Thr Ile Leu Arg Asp Leu Glu Lys Leu Ala Gly Trp His Arg Ile
145                 150                 155                 160

Ala Ile Ile Phe Ile Leu Ser Gly Ile Thr Gly Asn Leu Ala Ser Ala
                165                 170                 175

Ile Phe Leu Pro Tyr Arg Ala Glu Val Gly Pro Ala Gly Ser Gln Phe
            180                 185                 190

Gly Leu Leu Ala Cys Leu Phe Val Glu Leu Phe Gln Ser Trp Pro Leu
        195                 200                 205

Leu Glu Arg Pro Trp Lys Ala Phe Leu Asn Leu Ser Ala Ile Val Leu
    210                 215                 220

Phe Leu Phe Ile Cys Gly Leu Leu Pro Trp Ile Asp Asn Ile Ala His
225                 230                 235                 240

Ile Phe Gly Phe Leu Ser Gly Leu Leu Leu Ala Phe Ala Phe Leu Pro
                245                 250                 255

Tyr Ile Thr Phe Gly Thr Ser Asp Lys Tyr Arg Lys Arg Ala Leu Ile
            260                 265                 270

Leu Val Ser Leu Leu Ala Phe Ala Gly Leu Phe Ala Ala Leu Val Leu
        275                 280                 285

Trp Leu Tyr Ile Tyr Pro Ile Asn Trp Pro Trp Ile Glu His Leu Thr
    290                 295                 300

Cys Phe Pro Phe Thr Ser Arg Phe Cys Glu Lys Tyr Glu Leu Asp Gln
305                 310                 315                 320

Val Leu His 




<210> 2719
<211> 147
<212> PRT
<213> Homo sapiens

<400> 2719
Met Ala Asn Thr Thr Gly Glu Pro Glu Glu Val Ser Gly Ala Leu Ser
  1               5                  10                  15

Pro Pro Ser Ala Ser Ala Tyr Val Lys Leu Val Leu Leu Gly Leu Ile
             20                  25                  30

Met Cys Val Ser Leu Ala Gly Asn Ala Ile Leu Ser Leu Leu Val Leu
         35                  40                  45

Lys Glu Arg Ala Leu His Lys Ala Pro Tyr Tyr Phe Leu Leu Asp Leu
     50                  55                  60

Cys Leu Ala Asp Gly Ile Arg Ser Ala Val Cys Phe Pro Phe Val Leu
 65                  70                  75                  80

Ala Ser Val Arg His Gly Ser Ser Trp Thr Phe Ser Ala Leu Ser Cys
                 85                  90                  95

Lys Ile Val Ala Phe Met Ala Val Leu Phe Cys Phe His Ala Ala Phe
            100                 105                 110

Met Leu Phe Cys Ile Ser Val Thr Arg Tyr Met Ala Ile Ala His His
        115                 120                 125

Arg Phe Tyr Ala Lys Arg Met Thr Leu Trp Thr Cys Ala Ala Val Ile
    130                 135                 140

Cys Met Ala 
145



<210> 2720
<211> 342
<212> PRT
<213> Homo sapiens

<400> 2720
Met Ala Lys Gln Ala Thr Val Val Leu Asn Cys Val Gly Pro Tyr Arg
  1               5                  10                  15

Phe Tyr Gly Glu Pro Val Ile Lys Ala Cys Ile Glu Asn Gly Ala Ser
             20                  25                  30

Cys Ile Asp Ile Ser Gly Glu Pro Gln Phe Leu Glu Leu Met Gln Leu
         35                  40                  45

Lys Tyr His Glu Lys Ala Ala Asp Lys Gly Val Tyr Ile Ile Gly Ser
     50                  55                  60

Ser Gly Phe Asp Ser Ile Pro Ala Asp Leu Gly Val Ile Tyr Thr Arg
 65                  70                  75                  80

Asn Lys Met Asn Gly Thr Leu Thr Ala Val Glu Ser Phe Leu Thr Ile
                 85                  90                  95

His Ser Gly Pro Glu Gly Leu Ser Ile His Asp Gly Thr Trp Lys Ser
            100                 105                 110

Ala Ile Tyr Gly Phe Gly Asp Gln Ser Asn Leu Arg Lys Leu Arg Asn
        115                 120                 125

Val Ser Asn Leu Lys Pro Val Pro Leu Ile Gly Pro Lys Leu Lys Arg
    130                 135                 140

Arg Trp Pro Ile Ser Tyr Cys Arg Glu Leu Lys Gly Tyr Ser Ile Pro
145                 150                 155                 160

Phe Met Gly Ser Asp Val Ser Val Val Arg Arg Thr Gln Arg Tyr Leu
                165                 170                 175

Tyr Glu Asn Leu Glu Glu Ser Pro Val Gln Tyr Ala Ala Tyr Val Thr
            180                 185                 190

Val Gly Gly Ile Thr Ser Val Ile Lys Leu Met Phe Ala Gly Leu Phe
        195                 200                 205

Phe Leu Phe Phe Val Arg Phe Gly Ile Gly Arg Gln Leu Leu Ile Lys
    210                 215                 220

Phe Pro Trp Phe Phe Ser Phe Gly Tyr Phe Ser Lys Gln Gly Pro Thr
225                 230                 235                 240

Gln Lys Gln Ile Asp Ala Ala Ser Phe Thr Leu Thr Phe Phe Gly Gln
                245                 250                 255

Gly Tyr Ser Gln Gly Thr Gly Thr Asp Lys Asn Lys Pro Asn Ile Lys
            260                 265                 270

Ile Cys Thr Gln Val Lys Gly Pro Glu Ala Gly Tyr Val Ala Thr Pro
        275                 280                 285

Ile Ala Met Val Gln Ala Ala Met Thr Leu Leu Ser Asp Ala Ser His
    290                 295                 300

Leu Pro Lys Ala Gly Gly Val Phe Thr Pro Gly Ala Ala Phe Ser Lys
305                 310                 315                 320

Thr Lys Leu Ile Asp Arg Leu Asn Lys His Gly Ile Glu Phe Ser Val
                325                 330                 335

Ile Ser Ser Ser Glu Val 
            340



<210> 2721
<211> 234
<212> PRT
<213> Homo sapiens

<400> 2721
Met Arg Lys Thr Arg Leu Trp Gly Leu Leu Trp Met Leu Phe Val Ser
  1               5                  10                  15

Glu Leu Arg Ala Ala Thr Lys Leu Thr Glu Glu Lys Tyr Glu Leu Lys
             20                  25                  30

Glu Gly Gln Thr Leu Asp Val Lys Cys Asp Tyr Thr Leu Glu Lys Phe
         35                  40                  45

Ala Ser Ser Gln Lys Ala Trp Gln Ile Ile Arg Asp Gly Glu Met Pro
     50                  55                  60

Lys Thr Leu Ala Cys Thr Glu Arg Pro Ser Lys Asn Ser His Pro Val
 65                  70                  75                  80

Gln Val Gly Arg Ile Ile Leu Glu Asp Tyr His Asp His Gly Leu Leu
                 85                  90                  95

Arg Val Arg Met Val Asn Leu Gln Val Glu Asp Ser Gly Leu Tyr Gln
            100                 105                 110

Cys Val Ile Tyr Gln Pro Pro Lys Glu Pro His Met Leu Phe Asp Arg
        115                 120                 125

Ile Arg Leu Val Val Thr Lys Gly Phe Ser Gly Thr Pro Gly Ser Asn
    130                 135                 140

Glu Asn Ser Thr Gln Asn Val Tyr Lys Ile Pro Pro Thr Thr Thr Lys
145                 150                 155                 160

Ala Leu Cys Pro Leu Tyr Thr Ser Pro Arg Thr Val Thr Gln Ala Pro
                165                 170                 175

Pro Lys Ser Thr Ala Asp Val Ser Thr Pro Asp Ser Glu Ile Asn Leu
            180                 185                 190

Thr Asn Val Thr Asp Ile Ile Arg Val Pro Val Phe Asn Ile Val Ile
        195                 200                 205

Leu Leu Ala Gly Gly Phe Leu Ser Lys Ser Leu Val Phe Ser Val Leu
    210                 215                 220

Phe Ala Val Thr Leu Arg Ser Phe Val Pro 
225                 230



<210> 2722
<211> 713
<212> PRT
<213> Homo sapiens

<400> 2722
Met Leu Leu Ala Thr Leu Leu Leu Leu Leu Leu Gly Gly Ala Leu Ala
  1               5                  10                  15

His Pro Asp Arg Ile Ile Phe Pro Asn His Ala Cys Glu Asp Pro Pro
             20                  25                  30

Ala Val Leu Leu Glu Val Gln Gly Thr Leu Gln Arg Pro Leu Val Arg
         35                  40                  45

Asp Ser Arg Thr Ser Pro Ala Asn Cys Thr Trp Leu Ile Leu Gly Ser
     50                  55                  60

Lys Glu Gln Thr Val Thr Ile Arg Phe Gln Lys Leu His Leu Ala Cys
 65                  70                  75                  80

Gly Ser Glu Arg Leu Thr Leu Arg Ser Pro Leu Gln Pro Leu Ile Ser
                 85                  90                  95

Leu Cys Glu Ala Pro Pro Ser Pro Leu Gln Leu Pro Gly Gly Asn Val
            100                 105                 110

Thr Ile Thr Tyr Ser Tyr Ala Gly Ala Arg Ala Pro Met Gly Gln Gly
        115                 120                 125

Phe Leu Leu Ser Tyr Ser Gln Asp Trp Leu Met Cys Leu Gln Glu Glu
    130                 135                 140

Phe Gln Cys Leu Asn His Arg Cys Val Ser Ala Val Gln Arg Cys Asp
145                 150                 155                 160

Gly Val Asp Ala Cys Gly Asp Gly Ser Asp Glu Ala Gly Cys Ser Ser
                165                 170                 175

Asp Pro Phe Pro Gly Leu Thr Pro Arg Pro Val Pro Ser Leu Pro Cys
            180                 185                 190

Asn Val Thr Leu Glu Asp Phe Tyr Gly Val Phe Ser Ser Pro Gly Tyr
        195                 200                 205

Thr His Leu Ala Ser Val Ser His Pro Gln Ser Cys His Trp Leu Leu
    210                 215                 220

Asp Pro His Asp Gly Arg Arg Leu Ala Val Arg Phe Thr Ala Leu Asp
225                 230                 235                 240

Leu Gly Phe Gly Asp Ala Val His Val Tyr Asp Gly Pro Gly Pro Pro
                245                 250                 255

Glu Ser Ser Arg Leu Leu Arg Ser Leu Thr His Phe Ser Asn Gly Lys
            260                 265                 270

Ala Val Thr Val Glu Thr Leu Ser Gly Gln Ala Val Val Ser Tyr His
        275                 280                 285

Thr Val Ala Trp Ser Asn Gly Arg Gly Phe Asn Ala Thr Tyr His Val
    290                 295                 300

Arg Gly Tyr Cys Leu Pro Trp Asp Arg Pro Cys Gly Leu Gly Ser Gly
305                 310                 315                 320

Leu Gly Ala Gly Glu Gly Leu Gly Glu Arg Cys Tyr Ser Glu Ala Gln
                325                 330                 335

Arg Cys Asp Gly Ser Trp Asp Cys Ala Asp Gly Thr Asp Glu Glu Asp
            340                 345                 350

Cys Pro Gly Cys Pro Pro Gly His Phe Pro Cys Gly Ala Ala Gly Thr
        355                 360                 365

Ser Gly Ala Thr Ala Cys Tyr Leu Pro Ala Asp Arg Cys Asn Tyr Gln
    370                 375                 380

Thr Phe Cys Ala Asp Gly Ala Asp Glu Arg Arg Cys Arg His Cys Gln
385                 390                 395                 400

Pro Gly Asn Phe Arg Cys Arg Asp Glu Lys Cys Val Tyr Glu Thr Trp
                405                 410                 415

Val Cys Asp Gly Gln Pro Asp Cys Ala Asp Gly Ser Asp Glu Trp Asp
            420                 425                 430

Cys Ser Tyr Val Leu Pro Arg Lys Val Ile Thr Ala Ala Val Ile Gly
        435                 440                 445

Ser Leu Val Cys Gly Leu Leu Leu Val Ile Ala Leu Gly Cys Thr Cys
    450                 455                 460

Lys Leu Tyr Ala Ile Arg Thr Gln Glu Tyr Ser Ile Phe Ala Pro Leu
465                 470                 475                 480

Ser Arg Met Glu Ala Glu Ile Val Gln Gln Gln Ala Pro Pro Ser Tyr
                485                 490                 495

Gly Gln Leu Ile Ala Gln Gly Ala Ile Pro Pro Val Glu Asp Phe Pro
            500                 505                 510

Thr Glu Asn Pro Asn Asp Asn Ser Val Leu Gly Asn Leu Arg Ser Leu
        515                 520                 525

Leu Gln Ile Leu Arg Gln Asp Met Thr Pro Gly Gly Gly Pro Gly Ala
    530                 535                 540

Arg Arg Arg Gln Arg Gly Arg Leu Met Arg Arg Leu Val Arg Arg Leu
545                 550                 555                 560

Arg Arg Trp Gly Leu Leu Pro Arg Thr Asn Thr Pro Ala Arg Ala Ser
                565                 570                 575

Glu Ala Arg Ser Gln Val Thr Pro Ser Ala Ala Pro Leu Glu Ala Leu
            580                 585                 590

Asp Gly Gly Thr Gly Pro Ala Arg Glu Gly Gly Ala Val Gly Gly Gln
        595                 600                 605

Asp Gly Glu Gln Ala Pro Pro Leu Pro Ile Lys Ala Pro Leu Pro Ser
    610                 615                 620

Ala Ser Thr Ser Pro Ala Pro Thr Thr Val Pro Glu Ala Pro Gly Pro
625                 630                 635                 640

Leu Pro Ser Leu Pro Leu Glu Pro Ser Leu Leu Ser Gly Val Val Gln
                645                 650                 655

Ala Leu Arg Gly Arg Leu Leu Pro Ser Leu Gly Pro Pro Gly Pro Thr
            660                 665                 670

Arg Ser Pro Pro Gly Pro His Thr Ala Val Leu Ala Leu Glu Asp Glu
        675                 680                 685

Asp Asp Val Leu Leu Val Pro Leu Ala Glu Pro Gly Val Trp Val Ala
    690                 695                 700

Glu Ala Glu Asp Glu Pro Leu Leu Thr 
705                 710



<210> 2723
<211> 941
<212> PRT
<213> Homo sapiens

<400> 2723
Met Val Phe Leu Pro Leu Lys Trp Ser Leu Ala Thr Met Ser Phe Leu
  1               5                  10                  15

Leu Ser Ser Leu Leu Ala Leu Leu Thr Val Ser Thr Pro Ser Trp Cys
             20                  25                  30

Gln Ser Thr Glu Ala Ser Pro Lys Arg Ser Asp Gly Thr Pro Phe Pro
         35                  40                  45

Trp Asn Lys Ile Arg Leu Pro Glu Tyr Val Ile Pro Val His Tyr Asp
     50                  55                  60

Leu Leu Ile His Ala Asn Leu Thr Thr Leu Thr Phe Trp Gly Thr Thr
 65                  70                  75                  80

Lys Val Glu Ile Thr Ala Ser Gln Pro Thr Ser Thr Ile Ile Leu His
                 85                  90                  95

Ser His His Leu Gln Ile Ser Arg Ala Thr Leu Arg Lys Gly Ala Gly
            100                 105                 110

Glu Arg Leu Ser Glu Glu Pro Leu Gln Val Leu Glu His Pro Pro Gln
        115                 120                 125

Glu Gln Ile Ala Leu Leu Ala Pro Glu Pro Leu Leu Val Gly Leu Pro
    130                 135                 140

Tyr Thr Val Val Ile His Tyr Ala Gly Asn Leu Ser Glu Thr Phe His
145                 150                 155                 160

Gly Phe Tyr Lys Ser Thr Tyr Arg Thr Lys Glu Gly Glu Leu Arg Ile
                165                 170                 175

Leu Ala Ser Thr Gln Phe Glu Pro Thr Ala Ala Arg Met Ala Phe Pro
            180                 185                 190

Cys Phe Asp Glu Pro Ala Phe Lys Ala Ser Phe Ser Ile Lys Ile Arg
        195                 200                 205

Arg Glu Pro Arg His Leu Ala Ile Ser Asn Met Pro Leu Val Lys Ser
    210                 215                 220

Val Thr Val Ala Glu Gly Leu Ile Glu Asp His Phe Asp Val Thr Val
225                 230                 235                 240

Lys Met Ser Thr Tyr Leu Val Ala Phe Ile Ile Ser Asp Phe Glu Ser
                245                 250                 255

Val Ser Lys Ile Thr Lys Ser Gly Val Lys Val Ser Val Tyr Ala Val
            260                 265                 270

Pro Asp Lys Met Asn Gln Ala Asp Tyr Ala Leu Asp Ala Ala Val Thr
        275                 280                 285

Leu Leu Glu Phe Tyr Glu Asp Tyr Phe Ser Ile Pro Tyr Pro Leu Pro
    290                 295                 300

Lys Gln Asp Leu Ala Ala Ile Pro Asp Phe Gln Ser Gly Ala Met Glu
305                 310                 315                 320

Asn Trp Gly Leu Thr Thr Tyr Arg Glu Ser Ala Leu Leu Phe Asp Ala
                325                 330                 335

Glu Lys Ser Ser Ala Ser Ser Lys Leu Gly Ile Thr Met Thr Val Ala
            340                 345                 350

His Glu Leu Ala His Gln Trp Phe Gly Asn Leu Val Thr Met Glu Trp
        355                 360                 365

Trp Asn Asp Leu Trp Leu Asn Glu Gly Phe Ala Lys Phe Met Glu Phe
    370                 375                 380

Val Ser Val Ser Val Thr His Pro Glu Leu Lys Val Gly Asp Tyr Phe
385                 390                 395                 400

Phe Gly Lys Cys Phe Asp Ala Met Glu Val Asp Ala Leu Asn Ser Ser
                405                 410                 415

His Pro Val Ser Thr Pro Val Glu Asn Pro Ala Gln Ile Arg Glu Met
            420                 425                 430

Phe Asp Asp Val Ser Tyr Asp Lys Gly Ala Cys Ile Leu Asn Met Leu
        435                 440                 445

Arg Glu Tyr Leu Ser Ala Asp Ala Phe Lys Ser Gly Ile Val Gln Tyr
    450                 455                 460

Leu Gln Lys His Ser Tyr Lys Asn Thr Lys Asn Glu Asp Leu Trp Asp
465                 470                 475                 480

Ser Met Ala Ser Ile Cys Pro Thr Asp Gly Val Lys Gly Met Asp Gly
                485                 490                 495

Phe Cys Ser Arg Ser Gln His Ser Ser Ser Ser Ser His Trp His Gln
            500                 505                 510

Glu Gly Val Asp Val Lys Thr Met Met Asn Thr Trp Thr Leu Gln Arg
        515                 520                 525

Gly Phe Pro Leu Ile Thr Ile Thr Val Arg Gly Arg Asn Val His Met
    530                 535                 540

Lys Gln Glu His Tyr Met Lys Gly Ser Asp Gly Ala Pro Asp Thr Gly
545                 550                 555                 560

Tyr Leu Trp His Val Pro Leu Thr Phe Ile Thr Ser Lys Ser Asp Met
                565                 570                 575

Val His Arg Phe Leu Leu Lys Thr Lys Thr Asp Val Leu Ile Leu Pro
            580                 585                 590

Glu Glu Val Glu Trp Ile Lys Phe Asn Val Gly Met Asn Gly Tyr Tyr
        595                 600                 605

Ile Val His Tyr Glu Asp Asp Gly Trp Asp Ser Leu Thr Gly Leu Leu
    610                 615                 620

Lys Gly Thr His Thr Ala Val Ser Ser Asn Asp Arg Ala Ser Leu Ile
625                 630                 635                 640

Asn Asn Ala Phe Gln Leu Val Ser Ile Gly Lys Leu Ser Ile Glu Lys
                645                 650                 655

Ala Leu Asp Leu Ser Leu Tyr Leu Lys His Glu Thr Glu Ile Met Pro
            660                 665                 670

Val Phe Gln Gly Leu Asn Glu Leu Ile Pro Met Tyr Lys Leu Met Glu
        675                 680                 685

Lys Arg Asp Met Asn Glu Val Glu Thr Gln Phe Lys Ala Phe Leu Ile
    690                 695                 700

Arg Leu Leu Arg Asp Leu Ile Asp Lys Gln Thr Trp Thr Asp Glu Gly
705                 710                 715                 720

Ser Val Ser Glu Arg Met Leu Arg Ser Glu Leu Leu Leu Leu Ala Cys
                725                 730                 735

Val His Asn Tyr Gln Pro Cys Val Gln Arg Ala Glu Gly Tyr Phe Arg
            740                 745                 750

Lys Trp Lys Glu Ser Asn Gly Asn Leu Ser Leu Pro Val Asp Val Thr
        755                 760                 765

Leu Ala Val Phe Ala Val Gly Ala Gln Ser Thr Glu Gly Trp Asp Phe
    770                 775                 780

Leu Tyr Ser Lys Tyr Gln Phe Ser Leu Ser Ser Thr Glu Lys Ser Gln
785                 790                 795                 800

Ile Glu Phe Ala Leu Cys Arg Thr Gln Asn Lys Glu Lys Leu Gln Trp
                805                 810                 815

Leu Leu Asp Glu Ser Phe Lys Gly Asp Lys Ile Lys Thr Gln Glu Phe
            820                 825                 830

Pro Gln Ile Leu Thr Leu Ile Gly Arg Asn Pro Val Gly Tyr Pro Leu
        835                 840                 845

Ala Trp Gln Phe Leu Arg Lys Asn Trp Asn Lys Leu Val Gln Lys Phe
    850                 855                 860

Glu Leu Gly Ser Ser Ser Ile Ala His Met Val Met Gly Thr Thr Asn
865                 870                 875                 880

Gln Phe Ser Thr Arg Thr Arg Leu Glu Glu Val Lys Gly Phe Phe Ser
                885                 890                 895

Ser Leu Lys Glu Asn Gly Ser Gln Leu Arg Cys Val Gln Gln Thr Ile
            900                 905                 910

Glu Thr Ile Glu Glu Asn Ile Gly Trp Met Asp Lys Asn Phe Asp Lys
        915                 920                 925

Ile Arg Val Trp Leu Gln Ser Glu Lys Leu Glu Arg Met 
    930                 935                 940



<210> 2724
<211> 377
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2724
Met Arg Gly Gln Arg Ser Leu Leu Leu Gly Pro Ala Arg Leu Cys Leu
  1               5                  10                  15

Arg Leu Leu Leu Leu Leu Gly Tyr Arg Arg Arg Cys Pro Pro Leu Leu
             20                  25                  30

Arg Gly Leu Val Gln Arg Trp Arg Tyr Gly Lys Val Cys Leu Arg Ser
         35                  40                  45

Leu Leu Tyr Asn Ser Phe Gly Gly Ser Asp Thr Ala Val Asp Ala Ala
     50                  55                  60

Phe Xaa Pro Val Tyr Trp Leu Val Asp Asn Val Ile Arg Trp Phe Gly
 65                  70                  75                  80

Val Val Phe Val Val Leu Val Ile Val Leu Thr Gly Ser Ile Val Ala
                 85                  90                  95

Ile Ala Tyr Leu Cys Val Leu Pro Leu Ile Leu Arg Thr Tyr Ser Val
            100                 105                 110

Pro Arg Leu Cys Trp His Phe Phe Tyr Ser His Trp Asn Leu Ile Leu
        115                 120                 125

Ile Val Phe His Tyr Tyr Gln Ala Ile Thr Thr Pro Pro Gly Tyr Pro
    130                 135                 140

Pro Gln Gly Arg Asn Asp Ile Ala Thr Val Ser Ile Cys Lys Lys Cys
145                 150                 155                 160

Ile Tyr Pro Lys Pro Ala Arg Thr His His Cys Ser Ile Cys Asn Arg
                165                 170                 175

Cys Val Leu Lys Met Asp His His Cys Pro Trp Leu Asn Asn Cys Val
            180                 185                 190

Gly His Tyr Asn His Arg Tyr Phe Phe Ser Phe Cys Phe Phe Met Thr
        195                 200                 205

Leu Gly Cys Val Tyr Cys Ser Tyr Gly Ser Trp Asp Leu Phe Arg Glu
    210                 215                 220

Ala Tyr Ala Ala Ile Glu Lys Met Lys Gln Leu Asp Lys Asn Lys Leu
225                 230                 235                 240

Gln Ala Val Ala Asn Gln Thr Tyr His Gln Thr Pro Pro Pro Thr Phe
                245                 250                 255

Ser Phe Arg Glu Arg Met Thr His Lys Ser Leu Val Tyr Leu Trp Phe
            260                 265                 270

Leu Cys Ser Ser Val Ala Leu Ala Leu Gly Ala Leu Thr Val Trp His
        275                 280                 285

Ala Val Leu Ile Ser Arg Gly Glu Thr Ser Ile Glu Arg His Ile Asn
    290                 295                 300

Lys Lys Glu Arg Arg Arg Leu Gln Ala Lys Gly Arg Val Phe Arg Asn
305                 310                 315                 320

Pro Tyr Asn Tyr Gly Cys Leu Asp Asn Trp Lys Val Phe Leu Gly Val
                325                 330                 335

Asp Thr Gly Arg His Trp Leu Thr Arg Val Leu Leu Pro Ser Ser His
            340                 345                 350

Leu Pro His Gly Asn Gly Met Ser Trp Glu Pro Pro Pro Trp Val Thr
        355                 360                 365

Ala His Ser Ala Ser Val Met Ala Val 
    370                 375



<210> 2725
<211> 1082
<212> PRT
<213> Homo sapiens

<400> 2725
Met Gly Asp Gly Glu Leu Cys Gln Glu Ile Asn Ser Cys Leu Ile His
  1               5                  10                  15

His Gly Gly Cys His Ile His Ala Glu Cys Ile Ser Thr Gly Pro Gln
             20                  25                  30

Gln Val Ser Cys Ser Cys Arg Glu Gly Tyr Ser Gly Asp Gly Ile Arg
         35                  40                  45

Thr Cys Glu Leu Leu Asp Pro Cys Ser Lys Asn Asn Gly Gly Cys Ser
     50                  55                  60

Pro Tyr Ala Thr Cys Lys Ser Thr Gly Asp Gly Gln Arg Thr Cys Thr
 65                  70                  75                  80

Cys Asp Thr Ala His Thr Val Gly Asp Gly Leu Thr Cys Arg Ala Arg
                 85                  90                  95

Val Gly Leu Glu Leu Leu Arg Asp Lys His Ala Ser Phe Phe Ser Leu
            100                 105                 110

Arg Leu Leu Glu Tyr Lys Glu Leu Lys Gly Asp Gly Pro Phe Thr Ile
        115                 120                 125

Phe Val Pro His Ala Asp Leu Met Ser Asn Leu Ser Gln Asp Glu Leu
    130                 135                 140

Ala Arg Ile Arg Ala His Arg Gln Leu Val Phe Arg Tyr His Val Val
145                 150                 155                 160

Gly Cys Arg Arg Leu Arg Ser Glu Asp Leu Leu Glu Gln Gly Tyr Ala
                165                 170                 175

Thr Ala Leu Ser Gly His Pro Leu Arg Phe Ser Glu Arg Glu Gly Ser
            180                 185                 190

Ile Tyr Leu Asn Asp Phe Ala Arg Val Val Ser Ser Asp His Glu Ala
        195                 200                 205

Val Asn Gly Ile Leu His Phe Ile Asp Arg Val Leu Leu Pro Pro Glu
    210                 215                 220

Ala Leu His Trp Glu Pro Asp Asp Ala Pro Ile Pro Arg Arg Asn Val
225                 230                 235                 240

Thr Ala Ala Ala Gln Gly Phe Gly Tyr Lys Ile Phe Ser Gly Leu Leu
                245                 250                 255

Lys Val Ala Gly Leu Leu Pro Leu Leu Arg Glu Ala Ser His Arg Pro
            260                 265                 270

Phe Thr Met Leu Trp Pro Thr Asp Ala Ala Phe Arg Ala Leu Pro Pro
        275                 280                 285

Asp Arg Gln Ala Trp Leu Tyr His Glu Asp His Arg Asp Lys Leu Ala
    290                 295                 300

Ala Ile Leu Arg Gly His Met Ile Arg Asn Val Glu Ala Leu Ala Ser
305                 310                 315                 320

Asp Leu Pro Asn Leu Gly Pro Leu Arg Thr Met His Gly Thr Pro Ile
                325                 330                 335

Ser Phe Ser Cys Ser Arg Thr Arg Pro Gly Glu Leu Met Val Gly Glu
            340                 345                 350

Asp Asp Ala Arg Ile Val Gln Arg His Leu Pro Phe Glu Gly Gly Leu
        355                 360                 365

Ala Tyr Gly Ile Asp Gln Leu Leu Glu Pro Pro Gly Leu Gly Ala Arg
    370                 375                 380

Cys Asp His Phe Glu Thr Arg Pro Leu Arg Leu Asn Thr Cys Ser Ile
385                 390                 395                 400

Cys Gly Leu Glu Pro Pro Cys Pro Glu Gly Ser Gln Glu Gln Gly Ser
                405                 410                 415

Pro Glu Ala Cys Trp Arg Phe Tyr Pro Lys Phe Trp Thr Ser Pro Pro
            420                 425                 430

Leu His Ser Leu Gly Leu Arg Ser Val Trp Val His Pro Ser Leu Trp
        435                 440                 445

Gly Arg Pro Gln Gly Leu Gly Arg Gly Cys His Arg Asn Cys Val Thr
    450                 455                 460

Thr Thr Trp Lys Pro Ser Cys Cys Pro Gly His Tyr Gly Ser Glu Cys
465                 470                 475                 480

Gln Ala Cys Pro Gly Gly Pro Ser Ser Pro Cys Ser Asp Arg Gly Val
                485                 490                 495

Cys Met Asp Gly Met Ser Gly Ser Gly Gln Cys Leu Cys Arg Ser Gly
            500                 505                 510

Phe Ala Gly Thr Ala Cys Glu Leu Cys Ala Pro Gly Ala Phe Gly Pro
        515                 520                 525

His Cys Gln Ala Cys Arg Cys Thr Val His Gly Arg Cys Asp Glu Gly
    530                 535                 540

Leu Gly Gly Ser Gly Ser Cys Phe Cys Asp Glu Gly Trp Thr Gly Pro
545                 550                 555                 560

Arg Cys Glu Val Gln Leu Glu Leu Gln Pro Val Cys Thr Pro Pro Cys
                565                 570                 575

Ala Pro Glu Ala Val Cys Arg Ala Gly Asn Ser Cys Glu Cys Ser Leu
            580                 585                 590

Gly Tyr Glu Gly Asp Gly Arg Val Cys Thr Val Ala Asp Leu Cys Gln
        595                 600                 605

Asp Gly His Gly Gly Cys Ser Glu His Ala Asn Cys Ser Gln Val Gly
    610                 615                 620

Thr Met Val Thr Cys Thr Cys Leu Pro Asp Tyr Glu Gly Asp Gly Trp
625                 630                 635                 640

Ser Cys Arg Ala Arg Asn Pro Cys Thr Asp Gly His Arg Gly Gly Cys
                645                 650                 655

Ser Glu His Ala Asn Cys Leu Ser Thr Gly Leu Asn Thr Arg Arg Cys
            660                 665                 670

Glu Cys His Ala Gly Tyr Val Gly Asp Gly Leu Gln Cys Leu Glu Glu
        675                 680                 685

Ser Glu Pro Pro Val Asp Arg Cys Leu Gly Gln Pro Pro Pro Cys His
    690                 695                 700

Ser Asp Ala Met Cys Thr Asp Leu His Phe Gln Glu Lys Arg Ala Gly
705                 710                 715                 720

Val Phe His Leu Gln Ala Thr Ser Gly Pro Tyr Gly Leu Asn Phe Ser
                725                 730                 735

Glu Ala Glu Ala Ala Cys Glu Ala Gln Gly Ala Val Leu Ala Ser Phe
            740                 745                 750

Pro Gln Leu Ser Ala Ala Gln Gln Leu Gly Phe His Leu Cys Leu Met
        755                 760                 765

Gly Trp Leu Ala Asn Gly Ser Thr Ala His Pro Val Val Phe Pro Val
    770                 775                 780

Ala Asp Cys Gly Asn Gly Arg Val Gly Ile Val Ser Leu Gly Ala Arg
785                 790                 795                 800

Lys Asn Leu Ser Glu Arg Trp Asp Ala Tyr Cys Phe Arg Val Gln Asp
                805                 810                 815

Val Ala Cys Arg Cys Arg Asn Gly Phe Val Gly Asp Gly Ile Ser Thr
            820                 825                 830

Cys Asn Gly Lys Leu Leu Asp Val Leu Ala Ala Thr Ala Asn Phe Ser
        835                 840                 845

Thr Phe Tyr Gly Met Leu Leu Gly Tyr Ala Asn Ala Thr Gln Arg Gly
    850                 855                 860

Leu Asp Phe Leu Asp Phe Leu Asp Asp Glu Leu Thr Tyr Lys Thr Leu
865                 870                 875                 880

Phe Val Pro Val Asn Glu Gly Phe Val Asp Asn Met Thr Leu Ser Gly
                885                 890                 895

Pro Asp Leu Glu Leu His Ala Ser Asn Ala Thr Leu Leu Ser Ala Asn
            900                 905                 910

Ala Ser Gln Gly Lys Leu Leu Pro Ala His Ser Gly Leu Ser Leu Ile
        915                 920                 925

Ile Ser Asp Ala Gly Pro Asp Asn Ser Ser Trp Ala Pro Val Ala Pro
    930                 935                 940

Gly Thr Val Val Val Ser Arg Ile Ile Val Trp Asp Ile Met Ala Phe
945                 950                 955                 960

Asn Gly Ile Ile His Ala Leu Ala Ser Pro Leu Leu Ala Pro Pro Gln
                965                 970                 975

Pro Gln Ala Val Leu Ala Pro Glu Ala Pro Pro Val Ala Ala Gly Val
            980                 985                 990

Gly Ala Val Leu Ala Ala Gly Ala  Leu Leu Gly Leu Val  Ala Gly Ala
        995                 1000                 1005 

Leu Tyr  Leu Arg Ala Arg Gly  Lys Pro Met Gly Phe  Gly Phe Ser Ala
    1010                 1015                 1020 

Phe  Gln Ala Glu Asp Asp  Ala Asp Asp Asp Phe  Ser Pro Trp Gln Glu 
1025                 1030                 1035                 1040 

Gly Thr Asn Pro Thr  Leu Val Ser Val Pro  Asn Pro Val Phe Gly  Ser
                1045                 1050                 1055 

Asp Thr Phe Cys  Glu Pro Phe Asp Asp  Ser Leu Leu Glu Glu  Asp Phe
            1060                 1065                 1070 

Pro Asp Thr  Gln Arg Ile Leu Thr  Val Lys 
        1075                 1080 



<210> 2726
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (71)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2726
Met Leu Phe Phe Thr Thr Val Leu Ser Ile Asp Ile Arg Arg Met Glu
  1               5                  10                  15

Leu Ala Asp Leu Asn Lys Arg Leu Pro Pro Glu Ala Cys Leu Pro Ser
             20                  25                  30

Ala Lys Pro Val Gly Gln Pro Thr Arg Tyr Glu Arg Gln Leu Ala Val
         35                  40                  45

Arg Pro Ser Thr Pro His Thr Ile Thr Leu Gln Pro Ser Ser Phe Arg
     50                  55                  60

Asn Leu Arg Leu Pro Lys Xaa Leu Arg Val Val Tyr Phe Leu Ala Arg
 65                  70                  75                  80

Thr Arg Leu Ala Gln Arg Leu Ile Met Ala Gly Thr Val Val Trp Ile
                 85                  90                  95

Gly Ile Leu Val Tyr Thr Asp Pro Ala Gly Leu Arg Asn Tyr Leu Ala
            100                 105                 110






<210> 2727
<211> 693
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (680)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (681)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (682)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (683)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2727
Met Lys Asp Trp Leu Gly Gly Ser Glu Val Asn Pro Leu Trp Thr Ala
  1               5                  10                  15

Leu Leu Phe Leu Leu Cys His Ser Gly Ser Thr Ser Gly Ser His Asn
             20                  25                  30

Leu Gly Ala Gln Gln Thr Ser Ala Arg Ser Ala Ser Leu Ser Ser Ala
         35                  40                  45

Ala Thr Thr Gly Leu Thr Thr Gln Gln Arg Thr Ala Ile Glu Asn Ala
     50                  55                  60

Thr Val Ala Phe Phe Leu Gln Cys Ile Ser Cys His Pro Asn Asn Gln
 65                  70                  75                  80

Lys Leu Met Ala Gln Val Leu Cys Glu Leu Phe Gln Thr Ser Pro Gln
                 85                  90                  95

Arg Gly Asn Leu Pro Thr Ser Gly Asn Ile Ser Gly Phe Ile Arg Arg
            100                 105                 110

Leu Phe Leu Gln Leu Met Leu Glu Asp Glu Lys Val Thr Met Phe Leu
        115                 120                 125

Gln Ser Pro Cys Pro Leu Tyr Lys Gly Arg Ile Asn Ala Thr Ser His
    130                 135                 140

Val Ile Gln His Pro Met Tyr Gly Ala Gly His Lys Phe Arg Thr Leu
145                 150                 155                 160

His Leu Pro Val Ser Thr Thr Leu Ser Asp Val Leu Asp Arg Val Ser
                165                 170                 175

Asp Thr Pro Ser Ile Thr Ala Lys Leu Ile Ser Glu Gln Lys Asp Asp
            180                 185                 190

Lys Glu Lys Lys Asn His Glu Glu Lys Glu Lys Val Lys Ala Glu Asn
        195                 200                 205

Gly Phe Gln Asp Asn Tyr Ser Val Val Val Ala Ser Gly Leu Lys Ser
    210                 215                 220

Gln Ser Lys Arg Ala Val Ser Ala Thr Pro Pro Arg Pro Pro Ser Arg
225                 230                 235                 240

Arg Gly Arg Thr Ile Pro Asp Lys Ile Gly Ser Thr Ser Gly Ala Glu
                245                 250                 255

Ala Ala Asn Lys Ile Ile Thr Val Pro Val Phe His Leu Phe His Lys
            260                 265                 270

Leu Leu Ala Gly Gln Pro Leu Pro Ala Glu Met Thr Leu Ala Gln Leu
        275                 280                 285

Leu Thr Leu Leu Tyr Asp Arg Lys Leu Pro Gln Gly Tyr Arg Ser Ile
    290                 295                 300

Asp Leu Thr Val Lys Leu Gly Ser Arg Val Ile Thr Asp Pro Ser Leu
305                 310                 315                 320

Ser Lys Thr Asp Ser Tyr Lys Arg Leu His Pro Glu Lys Asp His Gly
                325                 330                 335

Asp Leu Leu Ala Ser Cys Pro Glu Asp Glu Ala Leu Thr Pro Gly Asp
            340                 345                 350

Glu Cys Met Asp Gly Ile Leu Asp Glu Ser Leu Leu Glu Thr Cys Pro
        355                 360                 365

Ile Gln Ser Pro Leu Gln Val Phe Ala Gly Met Gly Gly Leu Ala Leu
    370                 375                 380

Ile Ala Glu Arg Leu Pro Met Leu Tyr Pro Glu Val Ile Gln Gln Val
385                 390                 395                 400

Ser Ala Pro Val Val Thr Ser Thr Thr Gln Glu Lys Pro Lys Asp Ser
                405                 410                 415

Asp Gln Phe Glu Trp Val Thr Ile Glu Gln Ser Gly Glu Leu Val Tyr
            420                 425                 430

Glu Ala Pro Glu Thr Val Ala Ala Glu Pro Pro Pro Ile Lys Ser Ala
        435                 440                 445

Val Gln Thr Met Ser Pro Ile Pro Ala His Ser Leu Ala Ala Phe Gly
    450                 455                 460

Leu Phe Leu Arg Leu Pro Gly Tyr Ala Glu Val Leu Leu Lys Glu Arg
465                 470                 475                 480

Lys His Ala Gln Cys Leu Leu Arg Leu Val Leu Gly Val Thr Asp Asp
                485                 490                 495

Gly Glu Gly Ser His Ile Leu Gln Ser Pro Ser Ala Asn Val Leu Pro
            500                 505                 510

Thr Leu Pro Phe His Val Leu Arg Ser Leu Phe Ser Thr Thr Pro Leu
        515                 520                 525

Thr Thr Asp Asp Gly Val Leu Leu Arg Arg Met Ala Leu Glu Ile Gly
    530                 535                 540

Ala Leu His Leu Ile Leu Val Cys Leu Ser Ala Leu Ser His His Ser
545                 550                 555                 560

Pro Arg Val Pro Asn Ser Ser Val Asn Gln Thr Glu Pro Gln Val Ser
                565                 570                 575

Ser Ser His Asn Pro Thr Ser Thr Glu Glu Gln Gln Leu Tyr Trp Ala
            580                 585                 590

Lys Gly Thr Gly Phe Gly Thr Gly Ser Thr Ala Ser Gly Trp Asp Val
        595                 600                 605

Glu Gln Ala Leu Thr Lys Gln Arg Leu Glu Glu Glu His Val Thr Cys
    610                 615                 620

Leu Leu Gln Val Leu Ala Ser Tyr Ile Asn Pro Val Ser Ser Ala Val
625                 630                 635                 640

Asn Gly Glu Ala Gln Ser Ser His Glu Thr Arg Gly Gln Asn Ser Asn
                645                 650                 655

Ala Leu Pro Ser Val Leu Leu Glu Leu Leu Ser Gln Ser Cys Leu Ile
            660                 665                 670

Pro Ala Met Ser Ser Tyr Leu Xaa Xaa Xaa Xaa Asp Leu Lys Gly Lys
        675                 680                 685

Met Leu Lys Gln Glu 
    690



<210> 2728
<211> 117
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2728
Met Gly Val Leu Cys Arg Ser Leu Ala Gly Leu Gly Gly Leu Ser Leu
  1               5                  10                  15

Leu Gly Val Phe Cys Gly Gly Tyr Leu Met Ala Leu Ala Val Leu Ser
             20                  25                  30

Pro Cys Pro Pro Leu Val Gly Thr Ser Ala Gly Val Val Leu Val Val
         35                  40                  45

Leu Ser Trp Val Leu Cys Leu Gly Val Phe Ser Tyr Val Lys Val Ala
     50                  55                  60

Ala Ser Ser Leu Leu His Gly Gly Gly Arg Pro Ala Leu Leu Ala Ala
 65                  70                  75                  80

Gly Val Ala Ile Gln Val Gly Ser Leu Leu Gly Ala Val Ala Met Phe
                 85                  90                  95

Pro Pro Thr Ser Ile Tyr His Val Phe His Ser Arg Lys Asp Cys Ala
            100                 105                 110

Asp Pro Cys Asp Xaa 
        115



<210> 2729
<211> 477
<212> PRT
<213> Homo sapiens

<400> 2729
Met Ala Ala Pro Thr Pro Ala Arg Pro Val Leu Thr His Leu Leu Val
  1               5                  10                  15

Ala Leu Phe Gly Met Gly Ser Trp Ala Ala Val Asn Gly Ile Trp Val
             20                  25                  30

Glu Leu Pro Val Val Val Lys Glu Leu Pro Glu Gly Trp Ser Leu Pro
         35                  40                  45

Ser Tyr Val Ser Val Leu Val Ala Leu Gly Asn Leu Gly Leu Leu Val
     50                  55                  60

Val Thr Leu Trp Arg Arg Leu Ala Pro Gly Lys Asp Glu Gln Val Pro
 65                  70                  75                  80

Ile Arg Val Val Gln Val Leu Gly Met Val Gly Thr Ala Leu Leu Ala
                 85                  90                  95

Ser Leu Trp His His Val Ala Pro Val Ala Gly Gln Leu His Ser Val
            100                 105                 110

Ala Phe Leu Ala Leu Ala Phe Val Leu Ala Leu Ala Cys Cys Ala Ser
        115                 120                 125

Asn Val Thr Phe Leu Pro Phe Leu Ser His Leu Pro Pro Arg Phe Leu
    130                 135                 140

Arg Ser Phe Phe Leu Gly Gln Gly Leu Ser Ala Leu Leu Pro Cys Val
145                 150                 155                 160

Leu Ala Leu Val Gln Gly Val Gly Arg Leu Glu Cys Pro Pro Ala Pro
                165                 170                 175

Ile Asn Gly Thr Pro Gly Pro Pro Leu Asp Phe Leu Glu Arg Phe Pro
            180                 185                 190

Ala Ser Thr Phe Phe Trp Ala Leu Thr Ala Leu Leu Val Ala Ser Ala
        195                 200                 205

Ala Ala Phe Gln Gly Leu Leu Leu Leu Leu Pro Pro Pro Pro Ser Val
    210                 215                 220

Pro Thr Gly Glu Leu Gly Ser Gly Leu Gln Val Gly Ala Pro Gly Ala
225                 230                 235                 240

Glu Glu Glu Val Glu Glu Ser Ser Pro Leu Gln Glu Pro Pro Ser Gln
                245                 250                 255

Ala Ala Gly Thr Thr Pro Gly Pro Asp Pro Lys Ala Tyr Gln Leu Leu
            260                 265                 270

Ser Ala Arg Ser Ala Cys Leu Leu Gly Leu Leu Ala Ala Thr Asn Ala
        275                 280                 285

Leu Thr Asn Gly Val Leu Pro Ala Val Gln Ser Phe Ser Cys Leu Pro
    290                 295                 300

Tyr Gly Arg Leu Ala Tyr His Leu Ala Val Val Leu Gly Ser Ala Ala
305                 310                 315                 320

Asn Pro Leu Ala Cys Phe Leu Ala Met Gly Val Leu Cys Arg Tyr Thr
                325                 330                 335

Arg Thr Pro Ser Pro Cys Ala Gly Gly Thr Gln Gly Trp Glu Pro Gly
            340                 345                 350

Pro Gly Ala Val Ser Pro Asp Ile Leu Leu Ala His Cys Arg Ser Leu
        355                 360                 365

Ala Gly Leu Gly Gly Leu Ser Leu Leu Gly Val Phe Cys Gly Gly Tyr
    370                 375                 380

Leu Met Ala Leu Ala Val Leu Ser Pro Cys Pro Pro Leu Val Gly Thr
385                 390                 395                 400

Ser Ala Gly Val Val Leu Val Val Leu Ser Trp Val Leu Cys Leu Gly
                405                 410                 415

Val Phe Ser Tyr Val Lys Val Ala Ala Ser Ser Leu Leu His Gly Gly
            420                 425                 430

Gly Arg Pro Ala Leu Leu Ala Ala Gly Val Ala Ile Gln Val Gly Ser
        435                 440                 445

Leu Leu Gly Ala Val Ala Met Phe Pro Pro Thr Ser Ile Tyr His Val
    450                 455                 460

Phe His Ser Arg Lys Asp Cys Ala Asp Pro Cys Asp Ser 
465                 470                 475



<210> 2730
<211> 327
<212> PRT
<213> Homo sapiens

<400> 2730
Met Ala Glu Leu Pro Gly Pro Phe Leu Cys Gly Ala Leu Leu Gly Phe
  1               5                  10                  15

Leu Cys Leu Ser Gly Leu Ala Val Glu Val Lys Val Pro Thr Glu Pro
             20                  25                  30

Leu Ser Thr Pro Leu Gly Lys Thr Ala Glu Leu Thr Cys Thr Tyr Ser
         35                  40                  45

Thr Ser Val Gly Asp Ser Phe Ala Leu Glu Trp Ser Phe Val Gln Pro
     50                  55                  60

Gly Lys Pro Ile Ser Glu Ser His Pro Ile Leu Tyr Phe Thr Asn Gly
 65                  70                  75                  80

His Leu Tyr Pro Thr Gly Ser Lys Ser Lys Arg Val Ser Leu Leu Gln
                 85                  90                  95

Asn Pro Pro Thr Val Gly Val Ala Thr Leu Lys Leu Thr Asp Val His
            100                 105                 110

Pro Ser Asp Thr Gly Thr Tyr Leu Cys Gln Val Asn Asn Pro Pro Asp
        115                 120                 125

Phe Tyr Thr Asn Gly Leu Gly Leu Ile Asn Leu Thr Val Leu Val Pro
    130                 135                 140

Pro Ser Asn Pro Leu Cys Ser Gln Ser Gly Gln Thr Ser Val Gly Gly
145                 150                 155                 160

Ser Thr Ala Leu Arg Cys Ser Ser Ser Glu Gly Ala Pro Lys Pro Val
                165                 170                 175

Tyr Asn Trp Val Arg Leu Gly Thr Phe Pro Thr Pro Ser Pro Gly Ser
            180                 185                 190

Met Val Gln Asp Glu Val Ser Gly Gln Leu Ile Leu Thr Asn Leu Ser
        195                 200                 205

Leu Thr Ser Ser Gly Thr Tyr Arg Cys Val Ala Thr Asn Gln Met Gly
    210                 215                 220

Ser Ala Ser Cys Glu Leu Thr Leu Ser Val Thr Glu Pro Ser Gln Gly
225                 230                 235                 240

Arg Val Ala Gly Ala Leu Ile Gly Val Leu Leu Gly Val Leu Leu Leu
                245                 250                 255

Ser Val Ala Ala Phe Cys Leu Val Arg Phe Gln Lys Glu Arg Gly Lys
            260                 265                 270

Lys Pro Lys Glu Thr Tyr Gly Gly Ser Asp Leu Arg Glu Asp Ala Ile
        275                 280                 285

Ala Pro Gly Ile Ser Glu His Thr Cys Met Arg Ala Asp Ser Ser Lys
    290                 295                 300

Gly Phe Leu Glu Arg Pro Ser Ser Ala Ser Thr Val Thr Thr Thr Lys
305                 310                 315                 320

Ser Lys Leu Pro Met Val Val 
                325



<210> 2731
<211> 337
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (128)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (174)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (258)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2731
Met Asp Gln Asn Glu His Ser His Trp Gly Pro His Ala Lys Gly Gln
  1               5                  10                  15

Cys Ala Ser Arg Ser Glu Leu Arg Ile Ile Leu Val Gly Lys Thr Gly
             20                  25                  30

Thr Gly Lys Ser Ala Ala Gly Asn Ser Ile Leu Arg Lys Gln Ala Phe
         35                  40                  45

Glu Ser Lys Leu Gly Ser Gln Thr Leu Thr Lys Thr Cys Ser Lys Ser
     50                  55                  60

Gln Gly Ser Trp Gly Asn Arg Glu Ile Val Ile Ile Asp Thr Pro Asp
 65                  70                  75                  80

Met Phe Ser Trp Lys Asp His Cys Glu Ala Leu Tyr Lys Glu Val Gln
                 85                  90                  95

Arg Cys Tyr Leu Leu Ser Ala Pro Gly Pro His Val Leu Leu Leu Val
            100                 105                 110

Thr Gln Leu Gly Arg Tyr Thr Ser Gln Asp Gln Gln Ala Ala Gln Xaa
        115                 120                 125

Val Lys Glu Ile Phe Gly Lys Asp Ala Met Gly His Thr Ile Val Leu
    130                 135                 140

Phe Thr His Lys Glu Asp Leu Asn Gly Gly Ser Leu Met Asp Tyr Met
145                 150                 155                 160

His Asp Ser Asp Asn Lys Ala Leu Ser Lys Leu Val Ala Xaa Cys Gly
                165                 170                 175

Gly Arg Ile Cys Ala Phe Asn Asn Arg Ala Xaa Gly Ser Asn Gln Asp
            180                 185                 190

Asp Gln Val Lys Glu Leu Met Asp Cys Ile Glu Asp Leu Leu Met Glu
        195                 200                 205

Lys Asn Gly Asp His Tyr Thr Asn Gly Leu Tyr Ser Leu Ile Gln Arg
    210                 215                 220

Ser Lys Cys Gly Pro Val Gly Ser Asp Glu Arg Val Lys Glu Phe Lys
225                 230                 235                 240

Gln Ser Leu Ile Lys Tyr Met Glu Thr Gln Arg Ser Tyr Thr Ala Leu
                245                 250                 255

Ala Xaa Ala Asn Cys Leu Lys Gly Ala Leu Ile Lys Thr Gln Leu Cys
            260                 265                 270

Val Leu Phe Cys Ile Gln Leu Phe Leu Arg Leu Ile Ile Leu Trp Leu
        275                 280                 285

Cys Ile Leu His Ser Met Cys Asn Leu Phe Cys Cys Leu Leu Phe Ser
    290                 295                 300

Met Cys Asn Leu Phe Cys Ser Leu Leu Phe Ile Ile Pro Lys Lys Leu
305                 310                 315                 320

Met Ile Phe Leu Arg Thr Val Ile Arg Leu Glu Arg Lys Thr Pro Arg
                325                 330                 335

Leu 




<210> 2732
<211> 122
<212> PRT
<213> Homo sapiens

<400> 2732
Met Glu Gly Gln Asp Glu Val Ser Ala Arg Glu Gln His Phe His Ser
  1               5                  10                  15

Gln Val Arg Glu Ser Thr Ile Cys Phe Leu Leu Phe Ala Ile Leu Tyr
             20                  25                  30

Val Val Ser Tyr Phe Ile Ile Thr Arg Tyr Lys Arg Lys Ser Asp Glu
         35                  40                  45

Gln Glu Asp Glu Asp Ala Ile Val Asn Arg Ile Ser Leu Phe Leu Ser
     50                  55                  60

Thr Phe Thr Leu Ala Val Ser Ala Gly Ala Val Leu Leu Leu Pro Phe
 65                  70                  75                  80

Ser Ile Ile Ser Asn Glu Ile Leu Leu Ser Phe Pro Gln Asn Tyr Tyr
                 85                  90                  95

Ile Gln Trp Leu Asn Gly Ser Leu Ile His Gly Leu Trp Asn Leu Ala
            100                 105                 110

Ser Phe Phe Pro Thr Phe Gly Tyr Leu Tyr 
        115                 120



<210> 2733
<211> 178
<212> PRT
<213> Homo sapiens

<400> 2733
Met Ser Pro Ser Gly Arg Leu Cys Leu Leu Thr Ile Val Gly Leu Ile
  1               5                  10                  15

Leu Pro Thr Arg Gly Gln Thr Leu Lys Asp Thr Thr Ser Ser Ser Ser
             20                  25                  30

Ala Asp Ser Thr Ile Met Asp Ile Gln Val Pro Thr Arg Ala Pro Asp
         35                  40                  45

Ala Val Tyr Thr Glu Leu Gln Pro Thr Ser Pro Thr Pro Thr Trp Pro
     50                  55                  60

Ala Asp Glu Thr Pro Gln Pro Gln Thr Gln Thr Gln Gln Leu Glu Gly
 65                  70                  75                  80

Thr Asp Gly Pro Leu Val Thr Asp Pro Glu Thr His Lys Ser Thr Lys
                 85                  90                  95

Ala Ala His Pro Thr Asp Asp Thr Thr Thr Leu Ser Glu Arg Pro Ser
            100                 105                 110

Pro Ser Thr Asp Val Gln Thr Asp Pro Gln Thr Leu Lys Pro Ser Gly
        115                 120                 125

Phe His Glu Asp Asp Pro Phe Phe Tyr Asp Glu His Thr Leu Arg Lys
    130                 135                 140

Arg Gly Leu Leu Val Ala Ala Val Leu Phe Ile Thr Gly Ile Ile Ile
145                 150                 155                 160

Leu Thr Ser Gly Lys Cys Arg Gln Leu Ser Arg Leu Cys Arg Asn His
                165                 170                 175

Cys Arg 




<210> 2734
<211> 691
<212> PRT
<213> Homo sapiens

<400> 2734
Met Lys Arg Leu Pro Leu Leu Val Val Phe Ser Thr Leu Leu Asn Cys
  1               5                  10                  15

Ser Tyr Thr Gln Asn Cys Thr Lys Thr Pro Cys Leu Pro Asn Ala Lys
             20                  25                  30

Cys Glu Ile Arg Asn Gly Ile Glu Ala Cys Tyr Cys Asn Met Gly Phe
         35                  40                  45

Ser Gly Asn Gly Val Thr Ile Cys Glu Asp Asp Asn Glu Cys Gly Asn
     50                  55                  60

Leu Thr Gln Ser Cys Gly Glu Asn Ala Asn Cys Thr Asn Thr Glu Gly
 65                  70                  75                  80

Ser Tyr Tyr Cys Met Cys Val Pro Gly Phe Arg Ser Ser Ser Asn Gln
                 85                  90                  95

Asp Arg Phe Ile Thr Asn Asp Gly Thr Val Cys Ile Glu Asn Val Asn
            100                 105                 110

Ala Asn Cys His Leu Asp Asn Val Cys Ile Ala Ala Asn Ile Asn Lys
        115                 120                 125

Thr Leu Thr Lys Ile Arg Ser Ile Lys Glu Pro Val Ala Leu Leu Gln
    130                 135                 140

Glu Val Tyr Arg Asn Ser Val Thr Asp Leu Ser Pro Thr Asp Ile Ile
145                 150                 155                 160

Thr Tyr Ile Glu Ile Leu Ala Glu Ser Ser Ser Leu Leu Gly Tyr Lys
                165                 170                 175

Asn Asn Thr Ile Ser Ala Lys Asp Thr Leu Ser Asn Ser Thr Leu Thr
            180                 185                 190

Glu Phe Val Lys Thr Val Asn Asn Phe Val Gln Arg Asp Thr Phe Val
        195                 200                 205

Val Trp Asp Lys Leu Ser Val Asn His Arg Arg Thr His Leu Thr Lys
    210                 215                 220

Leu Met His Thr Val Glu Gln Ala Thr Leu Arg Ile Ser Gln Ser Phe
225                 230                 235                 240

Gln Lys Thr Thr Glu Phe Asp Thr Asn Ser Thr Asp Ile Ala Leu Lys
                245                 250                 255

Val Phe Phe Phe Asp Ser Tyr Asn Met Lys His Ile His Pro His Met
            260                 265                 270

Asn Met Asp Gly Asp Tyr Ile Asn Ile Phe Pro Lys Arg Lys Ala Ala
        275                 280                 285

Tyr Asp Ser Asn Gly Asn Val Ala Val Ala Phe Leu Tyr Tyr Lys Ser
    290                 295                 300

Ile Gly Pro Leu Leu Ser Ser Ser Asp Asn Phe Leu Leu Lys Pro Gln
305                 310                 315                 320

Asn Tyr Asp Asn Ser Glu Glu Glu Glu Arg Val Ile Ser Ser Val Ile
                325                 330                 335

Ser Val Ser Met Ser Ser Asn Pro Pro Thr Leu Tyr Glu Leu Glu Lys
            340                 345                 350

Ile Thr Phe Thr Leu Ser His Arg Lys Val Thr Asp Arg Tyr Arg Ser
        355                 360                 365

Leu Cys Ala Phe Trp Asn Tyr Ser Pro Asp Thr Met Asn Gly Ser Trp
    370                 375                 380

Ser Ser Glu Gly Cys Glu Leu Thr Tyr Ser Asn Glu Thr His Thr Ser
385                 390                 395                 400

Cys Arg Cys Asn His Leu Thr His Phe Ala Ile Leu Met Ser Ser Gly
                405                 410                 415

Pro Ser Ile Gly Ile Lys Asp Tyr Asn Ile Leu Thr Arg Ile Thr Gln
            420                 425                 430

Leu Gly Ile Ile Ile Ser Leu Ile Cys Leu Ala Ile Cys Ile Phe Thr
        435                 440                 445

Phe Trp Phe Phe Ser Glu Ile Gln Ser Thr Arg Thr Thr Ile His Lys
    450                 455                 460

Asn Leu Cys Cys Ser Leu Phe Leu Ala Glu Leu Val Phe Leu Val Gly
465                 470                 475                 480

Ile Asn Thr Asn Thr Asn Lys Leu Phe Cys Ser Ile Ile Ala Gly Leu
                485                 490                 495

Leu His Tyr Phe Phe Leu Ala Ala Phe Ala Trp Met Cys Ile Glu Gly
            500                 505                 510

Ile His Leu Tyr Leu Ile Val Val Gly Val Ile Tyr Asn Lys Gly Phe
        515                 520                 525

Leu His Lys Asn Phe Tyr Ile Phe Gly Tyr Leu Ser Pro Ala Val Val
    530                 535                 540

Val Gly Phe Ser Ala Ala Leu Gly Tyr Arg Tyr Tyr Gly Thr Thr Lys
545                 550                 555                 560

Val Cys Trp Leu Ser Thr Glu Asn Asn Phe Ile Trp Ser Phe Ile Gly
                565                 570                 575

Pro Ala Cys Leu Ile Ile Leu Val Asn Leu Leu Ala Phe Gly Val Ile
            580                 585                 590

Ile Tyr Lys Val Phe Arg His Thr Ala Gly Leu Lys Pro Glu Val Ser
        595                 600                 605

Cys Phe Glu Asn Ile Arg Ser Cys Ala Arg Gly Ala Leu Ala Leu Leu
    610                 615                 620

Phe Leu Leu Gly Thr Thr Trp Ile Phe Gly Val Leu His Val Val His
625                 630                 635                 640

Ala Ser Val Val Thr Ala Tyr Leu Phe Thr Val Ser Asn Ala Phe Gln
                645                 650                 655

Gly Met Phe Ile Phe Leu Phe Leu Cys Val Leu Ser Arg Lys Ile Gln
            660                 665                 670

Glu Glu Tyr Tyr Arg Leu Phe Lys Asn Val Pro Cys Cys Phe Gly Cys
        675                 680                 685

Leu Ser Cys 
    690



<210> 2735
<211> 116
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (5)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2735
Met Glu Phe Leu Xaa Pro Gly Ser Arg Lys Arg Lys Asp Tyr Ile Ser
  1               5                  10                  15

Asp His Lys Glu Cys Leu Ala Tyr Gly Glu Ile Phe Gln Asn Glu Gly
             20                  25                  30

Gly Tyr Tyr Leu Cys Gly His Gly Lys Thr Phe Ala Met Ala Val Cys
         35                  40                  45

Leu Ser Gly His Leu Leu Met Xaa Leu Asp Gln Ile Tyr Val Asp Ala
     50                  55                  60

Asp Ile Trp Asp Thr Cys Leu Gly Phe Gly Ala Val Ala Gln Asn Cys
 65                  70                  75                  80

Val Ser Leu Tyr Val Thr Val Leu Pro Leu Phe Ile Leu Ser Lys Val
                 85                  90                  95

Ser Leu Tyr Ile Cys Phe Thr Ile Cys Glu Arg Val Tyr His Asn Thr
            100                 105                 110

Glu Val Phe Ser 
        115



<210> 2736
<211> 362
<212> PRT
<213> Homo sapiens

<400> 2736
Met Pro Phe Ala Tyr Phe Phe Thr Glu Ser Glu Gly Phe Ala Gly Ser
  1               5                  10                  15

Arg Lys Gly Val Leu Gly Arg Val Tyr Glu Thr Val Val Met Leu Met
             20                  25                  30

Leu Leu Thr Leu Leu Val Leu Gly Met Val Trp Val Ala Ser Ala Ile
         35                  40                  45

Val Asp Lys Asn Lys Ala Asn Arg Glu Ser Leu Tyr Asp Phe Trp Glu
     50                  55                  60

Tyr Tyr Leu Pro Tyr Leu Tyr Ser Cys Ile Ser Phe Leu Gly Val Leu
 65                  70                  75                  80

Leu Leu Leu Val Cys Thr Pro Leu Gly Leu Ala Arg Met Phe Ser Val
                 85                  90                  95

Thr Gly Lys Leu Leu Val Lys Pro Arg Leu Leu Glu Asp Leu Glu Glu
            100                 105                 110

Gln Leu Tyr Cys Ser Ala Phe Glu Glu Ala Ala Leu Thr Arg Arg Ile
        115                 120                 125

Cys Asn Pro Thr Ser Cys Trp Leu Pro Leu Asp Met Glu Leu Leu His
    130                 135                 140

Arg Gln Val Leu Ala Leu Gln Thr Gln Arg Val Leu Leu Glu Lys Arg
145                 150                 155                 160

Arg Lys Ala Ser Ala Trp Gln Arg Asn Leu Gly Tyr Pro Leu Ala Met
                165                 170                 175

Leu Cys Leu Leu Val Leu Thr Gly Leu Ser Val Leu Ile Val Ala Ile
            180                 185                 190

His Ile Leu Glu Leu Leu Ile Asp Glu Ala Ala Met Pro Arg Gly Met
        195                 200                 205

Gln Gly Thr Ser Leu Gly Gln Val Ser Phe Ser Lys Leu Gly Ser Phe
    210                 215                 220

Gly Ala Val Ile Gln Val Val Leu Ile Phe Tyr Leu Met Val Ser Ser
225                 230                 235                 240

Val Val Gly Phe Tyr Ser Ser Pro Leu Phe Arg Ser Leu Arg Pro Arg
                245                 250                 255

Trp His Asp Thr Ala Met Thr Gln Ile Ile Gly Asn Cys Val Cys Leu
            260                 265                 270

Leu Val Leu Ser Ser Ala Leu Pro Val Phe Ser Arg Thr Leu Gly Leu
        275                 280                 285

Thr Arg Phe Asp Leu Leu Gly Asp Phe Gly Arg Phe Asn Trp Leu Gly
    290                 295                 300

Asn Phe Tyr Ile Val Phe Leu Tyr Asn Ala Ala Phe Ala Gly Leu Thr
305                 310                 315                 320

Thr Leu Cys Leu Val Lys Thr Phe Thr Ala Ala Val Arg Ala Glu Leu
                325                 330                 335

Ile Arg Ala Phe Gly Leu Asp Arg Leu Pro Leu Pro Val Ser Gly Phe
            340                 345                 350

Pro Gln Ala Ser Arg Lys Thr Gln His Gln 
        355                 360



<210> 2737
<211> 321
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (142)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (301)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (302)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2737
Met Glu Asp Lys Arg Asn Ile Gln Ile Ile Glu Trp Glu His Leu Asp
  1               5                  10                  15

Lys Lys Lys Phe Tyr Val Phe Gly Val Ala Met Thr Met Met Ile Arg
             20                  25                  30

Val Ser Val Tyr Pro Phe Thr Leu Ile Arg Thr Arg Leu Gln Val Gln
         35                  40                  45

Lys Gly Lys Ser Leu Tyr His Gly Thr Phe Asp Ala Phe Ile Lys Ile
     50                  55                  60

Leu Arg Ala Asp Gly Ile Thr Gly Leu Tyr Arg Gly Phe Leu Val Asn
 65                  70                  75                  80

Thr Phe Thr Leu Ile Ser Gly Gln Cys Tyr Val Thr Thr Tyr Glu Leu
                 85                  90                  95

Thr Arg Lys Phe Val Ala Asp Tyr Ser Gln Ser Asn Thr Val Lys Ser
            100                 105                 110

Leu Val Ala Gly Gly Ser Ala Ser Leu Val Ala Gln Ser Ile Thr Val
        115                 120                 125

Pro Ile Asp Val Val Ser Gln His Leu Met Met Gln Arg Xaa Gly Glu
    130                 135                 140

Lys Met Gly Arg Phe Gln Val Arg Gly Asn Pro Glu Gly Gln Gly Val
145                 150                 155                 160

Val Ala Phe Gly Gln Thr Lys Asp Ile Ile Arg Gln Ile Leu Gln Ala
                165                 170                 175

Asp Gly Leu Arg Gly Phe Tyr Arg Gly Tyr Val Ala Ser Leu Leu Thr
            180                 185                 190

Tyr Ile Pro Asn Ser Ala Val Trp Trp Pro Phe Tyr His Phe Tyr Ala
        195                 200                 205

Glu Gln Leu Ser Tyr Leu Cys Pro Lys Glu Cys Pro His Ile Val Phe
    210                 215                 220

Gln Ala Val Ser Gly Pro Leu Ala Ala Ala Thr Ala Ser Ile Leu Thr
225                 230                 235                 240

Asn Pro Met Asp Val Ile Arg Thr Arg Val Gln Val Glu Gly Lys Asn
                245                 250                 255

Ser Ile Ile Leu Thr Phe Arg Gln Leu Met Ala Glu Glu Gly Pro Trp
            260                 265                 270

Gly Leu Met Lys Gly Leu Ser Ala Arg Ile Ile Ser Ala Thr Pro Ser
        275                 280                 285

Thr Ile Val Ile Val Val Gly Tyr Glu Ser Leu Lys Xaa Xaa Ala Pro
    290                 295                 300

Val Ser Ile Gln Glu Cys Ser His Pro Lys Gly Trp Thr His Gly Ser
305                 310                 315                 320

Phe 




<210> 2738
<211> 104
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (57)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (66)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2738
Met Pro Trp Cys Leu Leu Pro Val Leu Ser Val Leu His Trp Ser Thr
  1               5                  10                  15

Glu Asp Thr Arg Ser Cys Gly Ala Gln Gly Gly Gly Pro Pro Leu Pro
             20                  25                  30

Pro Arg Gly Met Ala Gly Thr Val Leu Gly Val Gly Ala Gly Val Phe
         35                  40                  45

Ile Leu Ala Leu Leu Trp Val Ala Xaa Leu Leu Leu Cys Val Leu Leu
     50                  55                  60

Ser Xaa Xaa Phe Arg Gly Gly Glu Val Leu Cys Ser Phe Phe Ile Leu
 65                  70                  75                  80

Arg Cys Cys Asp His His Ile Ile Leu Leu Leu Phe Pro Gly Val Val
                 85                  90                  95

Ile Ser Ser Pro Arg Ser Gly Ser 
            100



<210> 2739
<211> 168
<212> PRT
<213> Homo sapiens

<400> 2739
Met Gly Lys Asn Phe Ser Asp Ser Phe Leu Ser Arg Glu Cys Val Ile
  1               5                  10                  15

Arg Met Val Ser Gly Arg Phe Tyr Leu Ser Cys Leu Leu Leu Gly Ser
             20                  25                  30

Leu Gly Ser Met Cys Ile Leu Phe Thr Ile Tyr Trp Met Gln Tyr Trp
         35                  40                  45

Arg Gly Gly Phe Ala Trp Asn Gly Ser Ile Tyr Met Phe Asn Trp His
     50                  55                  60

Pro Val Leu Met Val Ala Gly Met Val Val Phe Tyr Gly Gly Ala Ser
 65                  70                  75                  80

Leu Val Tyr Arg Leu Pro Gln Ser Trp Val Gly Pro Lys Leu Pro Trp
                 85                  90                  95

Lys Leu Leu His Ala Ala Leu His Leu Met Ala Phe Val Leu Thr Val
            100                 105                 110

Val Gly Leu Val Ala Val Phe Thr Phe His Asn His Gly Arg Thr Ala
        115                 120                 125

Asn Leu Tyr Ser Leu His Ser Trp Leu Gly Ile Thr Thr Val Phe Leu
    130                 135                 140

Phe Ala Cys Gln Trp Phe Leu Gly Phe Ala Val Phe Leu Leu Pro Trp
145                 150                 155                 160

Ala Ser Met Trp Leu Arg Ser Ser 
                165



<210> 2740
<211> 282
<212> PRT
<213> Homo sapiens

<400> 2740
Met Ser Gly Gly Trp Met Ala Gln Val Gly Ala Trp Arg Thr Gly Ala
  1               5                  10                  15

Leu Gly Leu Ala Leu Leu Leu Leu Leu Gly Leu Gly Leu Gly Leu Glu
             20                  25                  30

Ala Ala Ala Ser Pro Leu Ser Thr Pro Thr Ser Ala Gln Ala Ala Gly
         35                  40                  45

Pro Ser Ser Gly Ser Cys Pro Pro Thr Lys Phe Gln Cys Arg Thr Ser
     50                  55                  60

Gly Leu Cys Val Pro Leu Thr Trp Arg Cys Asp Arg Asp Leu Asp Cys
 65                  70                  75                  80

Ser Asp Gly Ser Asp Glu Glu Glu Cys Arg Ile Glu Pro Cys Thr Gln
                 85                  90                  95

Lys Gly Gln Cys Pro Pro Pro Pro Gly Leu Pro Cys Pro Cys Thr Gly
            100                 105                 110

Val Ser Asp Cys Ser Gly Gly Thr Asp Lys Lys Leu Arg Asn Cys Ser
        115                 120                 125

Arg Leu Ala Cys Leu Ala Gly Glu Leu Arg Cys Thr Leu Ser Asp Asp
    130                 135                 140

Cys Ile Pro Leu Thr Trp Arg Cys Asp Gly His Pro Asp Cys Pro Asp
145                 150                 155                 160

Ser Ser Asp Glu Leu Gly Cys Gly Thr Asn Glu Ile Leu Pro Glu Gly
                165                 170                 175

Asp Ala Thr Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val Thr Ser
            180                 185                 190

Leu Arg Asn Ala Thr Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val
        195                 200                 205

Pro Ser Val Gly Asn Ala Thr Ser Ser Ser Ala Gly Asp Gln Ser Gly
    210                 215                 220

Ser Pro Thr Ala Tyr Gly Val Ile Ala Ala Ala Ala Val Leu Ser Ala
225                 230                 235                 240

Ser Leu Val Thr Ala Thr Leu Leu Leu Leu Ser Trp Leu Arg Ala Gln
                245                 250                 255

Glu Arg Leu Arg Pro Leu Gly Leu Leu Val Ala Met Lys Glu Ser Leu
            260                 265                 270

Leu Leu Ser Glu Gln Lys Thr Ser Leu Pro 
        275                 280



<210> 2741
<211> 439
<212> PRT
<213> Homo sapiens

<400> 2741
Met Val Asp Asn Leu Gln Gly Asp Ser Gly Arg Gly Tyr Tyr Leu Glu
  1               5                  10                  15

Met Leu Ile Gly Thr Pro Pro Gln Lys Leu Gln Ile Leu Val Asp Thr
             20                  25                  30

Gly Ser Ser Asn Phe Ala Val Ala Gly Thr Pro His Ser Tyr Ile Asp
         35                  40                  45

Thr Tyr Phe Asp Thr Glu Arg Ser Ser Thr Tyr Arg Ser Lys Gly Phe
     50                  55                  60

Asp Val Thr Val Lys Tyr Thr Gln Gly Ser Trp Thr Gly Phe Val Gly
 65                  70                  75                  80

Glu Asp Leu Val Thr Ile Pro Lys Gly Phe Asn Thr Ser Phe Leu Val
                 85                  90                  95

Asn Ile Ala Thr Ile Phe Glu Ser Glu Asn Phe Phe Leu Pro Gly Ile
            100                 105                 110

Lys Trp Asn Gly Ile Leu Gly Leu Ala Tyr Ala Thr Leu Ala Lys Pro
        115                 120                 125

Ser Ser Ser Leu Glu Thr Phe Phe Asp Ser Leu Val Thr Gln Ala Asn
    130                 135                 140

Ile Pro Asn Val Phe Ser Met Gln Met Cys Gly Ala Gly Leu Pro Val
145                 150                 155                 160

Ala Gly Ser Gly Thr Asn Gly Gly Ser Leu Val Leu Gly Gly Ile Glu
                165                 170                 175

Pro Ser Leu Tyr Lys Gly Asp Ile Trp Tyr Thr Pro Ile Lys Glu Glu
            180                 185                 190

Trp Tyr Tyr Gln Ile Glu Ile Leu Lys Leu Glu Ile Gly Gly Gln Ser
        195                 200                 205

Leu Asn Leu Asp Cys Arg Glu Tyr Asn Ala Asp Lys Ala Ile Val Asp
    210                 215                 220

Ser Gly Thr Thr Leu Leu Arg Leu Pro Gln Lys Val Phe Asp Ala Val
225                 230                 235                 240

Val Glu Ala Val Ala Arg Ala Ser Leu Ile Pro Glu Phe Ser Asp Gly
                245                 250                 255

Phe Trp Thr Gly Ser Gln Leu Ala Cys Trp Thr Asn Ser Glu Thr Pro
            260                 265                 270

Trp Ser Tyr Phe Pro Lys Ile Ser Ile Tyr Leu Arg Asp Glu Asn Ser
        275                 280                 285

Ser Arg Ser Phe Arg Ile Thr Ile Leu Pro Gln Leu Tyr Ile Gln Pro
    290                 295                 300

Met Met Gly Ala Gly Leu Asn Tyr Glu Cys Tyr Arg Phe Gly Ile Ser
305                 310                 315                 320

Pro Ser Thr Asn Ala Leu Val Ile Gly Ala Thr Val Met Glu Gly Phe
                325                 330                 335

Tyr Val Ile Phe Asp Arg Ala Gln Lys Arg Val Gly Phe Ala Ala Ser
            340                 345                 350

Pro Cys Ala Glu Ile Ala Gly Ala Ala Val Ser Glu Ile Ser Gly Pro
        355                 360                 365

Phe Ser Thr Glu Asp Val Ala Ser Asn Cys Val Pro Ala Gln Ser Leu
    370                 375                 380

Ser Glu Pro Ile Leu Trp Ile Val Ser Tyr Ala Leu Met Ser Val Cys
385                 390                 395                 400

Gly Ala Ile Leu Leu Val Leu Ile Val Leu Leu Leu Leu Pro Phe Arg
                405                 410                 415

Cys Gln Arg Arg Pro Arg Asp Pro Glu Val Val Asn Asp Glu Ser Ser
            420                 425                 430

Leu Val Arg His Arg Trp Lys 
        435



<210> 2742
<211> 151
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (74)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2742
Met Leu Arg Leu Lys Gln Pro Lys Pro Val Leu Gln Trp Gly Glu Gly
  1               5                  10                  15

Ala Phe Xaa Phe Pro Ser Ser Trp Leu Pro Leu Ile Leu Pro Gln Thr
             20                  25                  30

Ile Leu Asn Lys Ala Lys Asn Leu Ser Leu Ser Pro Pro Gln Ala Thr
         35                  40                  45

Ser Cys Pro Thr Pro Ala Cys Ala Gly Phe Ser Gly Thr Pro Xaa Ala
     50                  55                  60

His Gly Trp His Leu Ser Ala Cys Ser Xaa Ser Cys Leu Met Ala Ala
 65                  70                  75                  80

Ala Phe Pro Phe Tyr Phe Leu Phe Ser Pro Tyr Leu Ala Ile Phe Leu
                 85                  90                  95

Ser Asp Phe Tyr Asn Gly Arg Gly Ala Lys Ile Ala Val Leu Ser Phe
            100                 105                 110

Gly Pro Pro Gly Pro Ala Gly Gln Lys Pro Gly Ala Gly Arg Pro Trp
        115                 120                 125

Trp Ser Ser Cys Gly Trp Ala Arg Arg Glu Arg Pro Ser Arg Ile Ile
    130                 135                 140

Ile Ser Leu Val Leu Ile Asn 
145                 150



<210> 2743
<211> 370
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (221)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (231)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (251)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (317)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (369)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2743
Met Ala Phe Arg Arg Arg Thr Lys Ser Tyr Pro Leu Phe Ser Gln Glu
  1               5                  10                  15

Phe Val Ile His Asn His Ala Asp Ile Gly Phe Cys Leu Val Leu Cys
             20                  25                  30

Val Leu Ile Gly Leu Met Phe Glu Val Thr Ala Lys Thr Ala Phe Leu
         35                  40                  45

Phe Ile Leu Pro Gln Tyr Asn Ile Ser Val Pro Thr Ala Asp Ser Glu
     50                  55                  60

Thr Val His Tyr His Tyr Gly Pro Lys Asp Leu Val Thr Ile Leu Phe
 65                  70                  75                  80

Tyr Ile Phe Ile Thr Ile Ile Leu His Ala Val Val Gln Glu Tyr Ile
                 85                  90                  95

Leu Asp Lys Ile Ser Lys Arg Leu His Leu Ser Lys Val Lys His Ser
            100                 105                 110

Lys Phe Asn Glu Ser Gly Gln Leu Val Val Phe His Phe Thr Ser Val
        115                 120                 125

Ile Trp Cys Phe Tyr Val Val Val Thr Glu Gly Tyr Leu Thr Asn Pro
    130                 135                 140

Arg Ser Leu Trp Glu Asp Tyr Pro His Val His Leu Pro Phe Gln Val
145                 150                 155                 160

Lys Phe Phe Tyr Leu Cys Gln Leu Ala Tyr Trp Leu His Ala Leu Pro
                165                 170                 175

Glu Leu Tyr Phe Gln Lys Val Arg Lys Glu Glu Ile Pro Arg Gln Leu
            180                 185                 190

Gln Tyr Ile Cys Leu Tyr Leu Val His Ile Ala Gly Ala Tyr Leu Leu
        195                 200                 205

Asn Leu Ser Arg Leu Gly Leu Ile Leu Leu Leu Leu Xaa Tyr Ser Thr
    210                 215                 220

Glu Phe Leu Phe His Thr Xaa Arg Leu Phe Tyr Phe Ala Asp Glu Asn
225                 230                 235                 240

Asn Glu Lys Leu Phe Ser Ala Trp Ala Ala Xaa Phe Gly Val Thr Arg
                245                 250                 255

Leu Phe Ile Leu Thr Leu Ala Val Leu Ala Ile Gly Phe Gly Leu Ala
            260                 265                 270

Arg Met Glu Asn Gln Ala Phe Asp Pro Glu Lys Gly Asn Phe Asn Thr
        275                 280                 285

Leu Phe Cys Arg Leu Cys Val Leu Leu Leu Val Cys Ala Ala Gln Ala
    290                 295                 300

Trp Leu Met Trp Arg Phe Ile His Ser Gln Leu Arg Xaa Trp Arg Glu
305                 310                 315                 320

Tyr Trp Asn Glu Gln Ser Ala Lys Arg Arg Val Pro Ala Thr Pro Arg
                325                 330                 335

Leu Pro Ala Arg Leu Ile Lys Arg Glu Ser Gly Tyr His Glu Asn Gly
            340                 345                 350

Val Val Lys Ala Glu Asn Gly Thr Ser Pro Arg Thr Lys Lys Leu Lys
        355                 360                 365

Xaa Pro 
    370



<210> 2744
<211> 184
<212> PRT
<213> Homo sapiens

<400> 2744
Met Arg Leu Gly Leu Ser Gln Gly Ile Gln Val Trp Cys Arg Trp Glu
  1               5                  10                  15

Leu Arg Lys Arg Pro Arg Thr Gln Asn Ile Tyr Gln Met Ala Thr Phe
             20                  25                  30

Gly Thr Thr Ala Gly Phe Ser Gly Ile Phe Ser Asn Phe Leu Phe Arg
         35                  40                  45

Arg Cys Phe Lys Val Lys His Asp Ala Leu Lys Thr Tyr Ala Ser Leu
     50                  55                  60

Ala Thr Leu Pro Phe Leu Ser Thr Val Val Thr Asp Lys Leu Phe Val
 65                  70                  75                  80

Ile Asp Ala Leu Tyr Ser Asp Asn Ile Ser Lys Glu Asn Cys Val Phe
                 85                  90                  95

Arg Ser Ser Leu Ile Gly Ile Val Cys Gly Val Phe Tyr Pro Ser Ser
            100                 105                 110

Leu Ala Phe Thr Lys Asn Gly Arg Leu Ala Thr Lys Tyr His Thr Val
        115                 120                 125

Pro Leu Pro Pro Lys Gly Arg Val Leu Ile His Trp Met Thr Leu Cys
    130                 135                 140

Gln Thr Gln Met Lys Leu Met Ala Ile Pro Leu Val Phe Gln Ile Met
145                 150                 155                 160

Phe Gly Ile Leu Asn Gly Leu Tyr His Tyr Ala Val Phe Glu Glu Thr
                165                 170                 175

Leu Glu Lys Thr Ile His Glu Glu 
            180



<210> 2745
<211> 140
<212> PRT
<213> Homo sapiens

<400> 2745
Met Ala Ala Ser Met His Gly Gln Pro Ser Pro Ser Leu Glu Asp Ala
  1               5                  10                  15

Lys Leu Arg Arg Pro Met Val Ile Glu Ile Ile Glu Lys Asn Phe Asp
             20                  25                  30

Tyr Leu Arg Lys Glu Met Thr Gln Asn Ile Tyr Gln Met Ala Thr Phe
         35                  40                  45

Gly Thr Thr Ala Gly Phe Ser Gly Ile Phe Ser Asn Phe Leu Phe Arg
     50                  55                  60

Arg Cys Phe Lys Val Lys His Asp Ala Leu Lys Thr Tyr Ala Ser Leu
 65                  70                  75                  80

Ala Thr Leu Pro Phe Leu Ser Thr Val Val Thr Asp Lys Leu Phe Val
                 85                  90                  95

Ile Asp Ala Leu Tyr Ser Asp Asn Ile Ser Lys Glu Asn Cys Val Phe
            100                 105                 110

Arg Ser Ser Leu Ile Gly Ile Val Cys Gly Val Phe Tyr Pro Ser Ser
        115                 120                 125

Leu Ala Phe Thr Lys Asn Gly Arg Leu Ala Thr Lys 
    130                 135                 140



<210> 2746
<211> 151
<212> PRT
<213> Homo sapiens

<400> 2746
Met Ala Ala Ser Ser Gln Gly Asn Phe Glu Gly Asn Phe Glu Ser Leu
  1               5                  10                  15

Asp Leu Ala Glu Phe Ala Lys Lys Gln Pro Trp Trp Arg Lys Leu Phe
             20                  25                  30

Gly Gln Glu Ser Gly Pro Ser Ala Glu Lys Tyr Ser Val Ala Thr Gln
         35                  40                  45

Leu Phe Ile Gly Gly Val Thr Gly Trp Cys Thr Gly Phe Ile Phe Gln
     50                  55                  60

Lys Val Gly Lys Leu Ala Ala Thr Ala Val Gly Gly Gly Phe Phe Leu
 65                  70                  75                  80

Leu Gln Leu Ala Asn His Thr Gly Tyr Ile Lys Val Asp Trp Gln Arg
                 85                  90                  95

Val Glu Lys Asp Met Lys Lys Ala Lys Glu Gln Leu Lys Ile Arg Lys
            100                 105                 110

Ser Asn Gln Ile Pro Thr Glu Val Arg Ser Lys Ala Glu Glu Val Val
        115                 120                 125

Ser Phe Val Lys Lys Asn Val Leu Val Thr Gly Gly Phe Phe Gly Gly
    130                 135                 140

Phe Leu Leu Gly Met Ala Ser 
145                 150



<210> 2747
<211> 358
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (63)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (67)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (132)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (267)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (301)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2747
Met Phe Ala Ser Gly Val Val Lys Leu Thr Ser Arg Cys Pro Ala Trp
  1               5                  10                  15

Trp Gly Leu Thr Ala Leu Thr Tyr His Tyr Glu Thr Gln Cys Leu Pro
             20                  25                  30

Thr Pro Ala Ala Trp Phe Ala His His Leu Pro Val Trp Leu His Lys
         35                  40                  45

Leu Ser Val Val Ala Thr Phe Leu Ile Glu Ile Ala Val Pro Xaa Leu
     50                  55                  60

Phe Phe Xaa Pro Ile Arg Arg Leu Arg Leu Ala Ala Phe Tyr Ser Gln
 65                  70                  75                  80

Val Leu Leu Gln Val Leu Ile Ile Ile Thr Gly Asn Tyr Asn Phe Phe
                 85                  90                  95

Asn Leu Met Thr Leu Val Leu Thr Thr Ala Leu Leu Asp Asp Gln His
            100                 105                 110

Leu Ala Ala Glu Pro Gly His Gly Ser Arg Lys Lys Thr Ala Thr Ser
        115                 120                 125

Trp Pro Lys Xaa Leu Leu Ala Thr Leu Ser Leu Leu Leu Glu Leu Ala
    130                 135                 140

Val Tyr Gly Leu Leu Ala Tyr Gly Thr Val His Tyr Phe Gly Leu Glu
145                 150                 155                 160

Val Asp Trp Gln Gln Arg Thr Ile His Ser Arg Thr Thr Phe Thr Phe
                165                 170                 175

His Gln Phe Ser Gln Trp Leu Lys Thr Leu Thr Leu Pro Thr Val Trp
            180                 185                 190

Leu Gly Val Ala Ser Leu Val Trp Glu Leu Leu Ser Ala Leu Trp Arg
        195                 200                 205

Trp Thr Gln Val Arg Gly Trp Leu Arg Lys Leu Ser Ala Val Val Gln
    210                 215                 220

Leu Ser Leu Val Gly Thr Ala Thr Val Ala Leu Phe Leu Ile Ser Leu
225                 230                 235                 240

Val Pro Tyr Ser Tyr Val Glu Pro Gly Thr His Gly Arg Leu Trp Thr
                245                 250                 255

Gly Ala His Arg Leu Phe Gly Ala Val Glu Xaa Leu Gln Leu Ala Asn
            260                 265                 270

Ser Tyr Gly Leu Phe Arg Arg Met Thr Gly Leu Gly Gly Arg Pro Glu
        275                 280                 285

Val Val Leu Glu Gly Ser Tyr Asp Gly His His Trp Xaa Glu Ile Glu
    290                 295                 300

Phe Met Tyr Lys Pro Gly Asn Leu Ser Arg Pro Pro Pro Val Val Val
305                 310                 315                 320

Pro His Gln Pro Arg Leu Val Leu Ala Asp Val Val Cys Ser Pro Gly
                325                 330                 335

Pro Thr His Ala Gln Pro Val Val His Lys Pro Gly Leu Ala Pro Ala
            340                 345                 350

Ala Gly Gln Gly Ser Gln 
        355



<210> 2748
<211> 201
<212> PRT
<213> Homo sapiens

<400> 2748
Met Glu Tyr His Pro Asp Leu Glu Asn Leu Asp Glu Asp Gly Tyr Thr
  1               5                  10                  15

Gln Leu His Phe Asp Ser Gln Ser Asn Thr Arg Ile Ala Val Val Ser
             20                  25                  30

Glu Lys Gly Ser Cys Ala Ala Ser Pro Pro Trp Arg Leu Ile Ala Val
         35                  40                  45

Ile Leu Gly Ile Leu Cys Leu Val Ile Leu Val Ile Ala Val Val Leu
     50                  55                  60

Gly Thr Met Gly Val Leu Ser Ser Pro Cys Pro Pro Asn Trp Ile Ile
 65                  70                  75                  80

Tyr Glu Lys Ser Cys Tyr Leu Phe Ser Met Ser Leu Asn Ser Trp Asp
                 85                  90                  95

Gly Ser Lys Arg Gln Cys Trp Gln Leu Gly Ser Asn Leu Leu Lys Ile
            100                 105                 110

Asp Ser Ser Asn Glu Leu Gly Phe Ile Val Lys Gln Val Ser Ser Gln
        115                 120                 125

Pro Asp Asn Ser Phe Trp Ile Gly Leu Ser Arg Pro Gln Thr Glu Val
    130                 135                 140

Pro Trp Leu Trp Glu Asp Gly Ser Thr Phe Ser Ser Asn Leu Phe Gln
145                 150                 155                 160

Ile Arg Thr Thr Ala Thr Gln Glu Asn Pro Ser Pro Asn Cys Val Trp
                165                 170                 175

Ile His Val Ser Val Ile Tyr Asp Gln Leu Cys Ser Val Pro Ser Tyr
            180                 185                 190

Ser Ile Cys Glu Lys Lys Phe Ser Met 
        195                 200



<210> 2749
<211> 399
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (312)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (383)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (394)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2749
Met Ser Arg Arg Asp Ser Glu Ser Thr Arg His Asp Ser Glu Thr Glu
  1               5                  10                  15

Asp Met Leu Trp Asp Asp Leu Leu His Gly Pro Glu Cys Arg Ser Ser
             20                  25                  30

Val Thr Ser Asp Ser Glu Gly Ala His Val Asn Thr Leu His Ser Gly
         35                  40                  45

Thr Lys Arg Asp Pro Lys Glu Asp Val Phe Gln Gln Asn His Leu Phe
     50                  55                  60

Trp Leu Gln Asn Ser Ser Pro Ser Ser Asp Arg Val Ser Ala Ile Ile
 65                  70                  75                  80

Trp Glu Gly Asn Glu Cys Lys Lys Met Asp Met Ser Val Leu Glu Ile
                 85                  90                  95

Ser Gly Ile Ile Met Ser Arg Val Asn Ala Tyr Gln Gln Gly Val Gly
            100                 105                 110

Tyr Gln Met Leu Gly Asn Val Val Thr Ile Gly Leu Ala Phe Phe Pro
        115                 120                 125

Phe Leu His Arg Leu Phe Arg Glu Lys Ser Leu Asp Gln Leu Lys Ser
    130                 135                 140

Ile Ser Ala Glu Glu Ile Leu Thr Leu Phe Cys Gly Ala Pro Pro Val
145                 150                 155                 160

Thr Pro Ile Ile Val Leu Ser Ile Ile Asn Phe Phe Glu Arg Leu Cys
                165                 170                 175

Leu Thr Trp Met Phe Phe Phe Met Met Cys Val Ala Glu Arg Thr Tyr
            180                 185                 190

Lys Gln Arg Phe Leu Phe Ala Lys Leu Phe Ser His Ile Thr Ser Ala
        195                 200                 205

Arg Lys Ala Arg Lys Tyr Glu Ile Pro His Phe Arg Leu Lys Lys Val
    210                 215                 220

Glu Asn Ile Lys Ile Trp Leu Ser Leu Arg Ser Tyr Leu Lys Arg Arg
225                 230                 235                 240

Gly Pro Gln Arg Ser Val Asp Val Val Val Ser Ser Val Phe Leu Leu
                245                 250                 255

Thr Leu Ser Ile Ala Phe Ile Cys Cys Ala Gln Val Leu Gln Gly His
            260                 265                 270

Lys Thr Phe Leu Asn Asp Ala Tyr Asn Trp Glu Phe Leu Ile Trp Glu
        275                 280                 285

Thr Ala Leu Leu Leu Phe Leu Leu Arg Leu Ala Ser Leu Gly Ser Glu
    290                 295                 300

Thr Asn Lys Lys Tyr Ser Asn Xaa Ser Ile Leu Leu Thr Glu Gln Ile
305                 310                 315                 320

Asn Leu Tyr Leu Lys Met Glu Lys Lys Pro Asn Lys Lys Glu Gln Leu
                325                 330                 335

Thr Leu Val Asn Asn Val Leu Lys Leu Ser Thr Lys Leu Leu Lys Glu
            340                 345                 350

Leu Asp Thr Pro Phe Arg Leu Tyr Gly Leu Thr Met Asn Pro Leu Ile
        355                 360                 365

Tyr Asn Ile Thr Arg Val Val Ile Leu Ser Ala Val Ser Gly Xaa Ile
    370                 375                 380

Ser Asp Leu Leu Gly Phe Asn Ile Arg Xaa Trp Lys Ile Lys Ser 
385                 390                 395



<210> 2750
<211> 250
<212> PRT
<213> Homo sapiens

<400> 2750
Met Ser Asn His Val Val Gly Gly Cys Arg Leu Arg Ala Ser Val Gly
  1               5                  10                  15

Ser Ser Thr Thr Val Ser Val Gly Ser Gly His Gly Thr Leu Ser Pro
             20                  25                  30

Ser Cys Thr Trp Ser Arg Val His Ser His Pro Pro Ser Cys Gly Glu
         35                  40                  45

Arg Leu Ala Arg Pro Gly Gln Ala Arg Gln Lys Val Ser Ala Lys Trp
     50                  55                  60

Pro Arg Pro His Pro Ala Ile Ser Gln Leu Leu Phe Ile Thr Phe Val
 65                  70                  75                  80

Pro His Leu Gly Val Cys Phe Leu His Leu Asp Thr Leu Pro Gly Arg
                 85                  90                  95

Ser Ser Glu Pro Asn Pro Arg Leu Cys Ser Val Gly Glu Gly Met Thr
            100                 105                 110

Ser Pro Pro Pro Asp Leu Pro Arg Val Leu Val Ser Leu Ser Ala Gly
        115                 120                 125

Gly Pro Leu Cys Val Phe Val Gln Phe Cys Cys Met Gly Phe Val Thr
    130                 135                 140

Gln Lys Leu Met Leu Arg Lys Ala Ser Leu Gly Pro Leu Pro Arg Ala
145                 150                 155                 160

Ser Glu Arg Pro Gly Val Pro Val Phe Leu Glu Met Gly Pro Ser Ala
                165                 170                 175

Ala Gly Cys Glu Ala Leu Arg Ser Ile Thr Gly Arg Ala Trp Arg Trp
            180                 185                 190

Trp Pro Pro Gly Thr Thr Leu Ser Cys Leu Phe Thr Phe His Tyr Gln
        195                 200                 205

Val Phe Ser Gly His Tyr Asp Leu Phe Pro Tyr Asn Ser Asp Leu Cys
    210                 215                 220

Ile Leu Leu Trp Pro Ala Val Ser Ala Gly Gly Ser Gln Arg Gly Thr
225                 230                 235                 240

Gly Arg Ala Ser Pro Cys Arg Thr Ala Glu 
                245                 250



<210> 2751
<211> 309
<212> PRT
<213> Homo sapiens

<400> 2751
Met Ala Pro Gln Ser Leu Pro Ser Ser Arg Met Ala Pro Leu Gly Met
  1               5                  10                  15

Leu Leu Gly Leu Leu Met Ala Ala Cys Phe Thr Phe Cys Leu Ser His
             20                  25                  30

Gln Asn Leu Lys Glu Phe Ala Leu Thr Asn Pro Glu Lys Ser Ser Thr
         35                  40                  45

Lys Glu Thr Glu Arg Lys Glu Thr Lys Ala Glu Glu Glu Leu Asp Ala
     50                  55                  60

Glu Val Leu Glu Val Phe His Pro Thr His Glu Trp Gln Ala Leu Gln
 65                  70                  75                  80

Pro Gly Gln Ala Val Pro Ala Gly Ser His Val Arg Leu Asn Leu Gln
                 85                  90                  95

Thr Gly Glu Arg Glu Ala Lys Leu Gln Tyr Glu Asp Lys Phe Arg Asn
            100                 105                 110

Asn Leu Lys Gly Lys Arg Leu Asp Ile Asn Thr Asn Thr Tyr Thr Ser
        115                 120                 125

Gln Asp Leu Lys Ser Ala Leu Ala Lys Phe Lys Glu Gly Ala Glu Met
    130                 135                 140

Glu Ser Ser Lys Glu Asp Lys Ala Arg Gln Ala Glu Val Lys Arg Leu
145                 150                 155                 160

Phe Arg Pro Ile Glu Glu Leu Lys Lys Asp Phe Asp Glu Leu Asn Val
                165                 170                 175

Val Ile Glu Thr Asp Met Gln Ile Met Val Arg Leu Ile Asn Lys Phe
            180                 185                 190

Asn Ser Ser Ser Ser Ser Leu Glu Glu Lys Ile Ala Ala Leu Phe Asp
        195                 200                 205

Leu Glu Tyr Tyr Val His Gln Gln Pro Gln Gly Pro Gly Gly Gly His
    210                 215                 220

Arg Arg Gly Ser Pro Ala Glu Ala Ala Gly His Pro Gly His Gly Ala
225                 230                 235                 240

Ala Ala His Cys Lys Glu Glu Gly Pro Val Cys Thr Val Leu Pro Ala
                245                 250                 255

Ala Pro Leu Pro Leu Cys Pro Ala Ala Val Pro Glu Ala Arg Gly Ala
            260                 265                 270

Ala Gly Pro Glu Asp Pro Gly Ala Gly Glu Gly His Gly Gly Ala Arg
        275                 280                 285

Arg Ala Arg Gly His Thr Ala Leu Arg Pro Gly His Gly Glu Asp Val
    290                 295                 300

Arg Arg Gly Gly Gly 
305



<210> 2752
<211> 171
<212> PRT
<213> Homo sapiens

<400> 2752
Met Lys Lys Cys Leu Leu Pro Val Leu Ile Thr Cys Met Gln Thr Ala
  1               5                  10                  15

Ile Cys Lys Asp Arg Met Met Met Ile Met Ile Leu Leu Val Asn Tyr
             20                  25                  30

Arg Pro Asp Glu Phe Ile Glu Cys Glu Asp Pro Val Asp His Val Gly
         35                  40                  45

Asn Ala Thr Ala Ser Gln Glu Leu Gly Tyr Gly Cys Leu Lys Phe Gly
     50                  55                  60

Gly Gln Ala Tyr Ser Asp Val Glu His Thr Ser Val Gln Cys His Ala
 65                  70                  75                  80

Leu Asp Gly Ile Glu Cys Ala Ser Pro Arg Thr Phe Leu Arg Glu Asn
                 85                  90                  95

Lys Pro Cys Ile Lys Tyr Thr Gly His Tyr Phe Ile Thr Thr Leu Leu
            100                 105                 110

Tyr Ser Phe Phe Leu Gly Cys Phe Gly Val Asp Arg Phe Cys Leu Gly
        115                 120                 125

His Thr Gly Thr Ala Val Gly Lys Leu Leu Thr Leu Gly Gly Leu Gly
    130                 135                 140

Ile Trp Trp Phe Val Asp Leu Ile Leu Leu Ile Thr Gly Gly Leu Met
145                 150                 155                 160

Pro Ser Asp Gly Ser Asn Trp Cys Thr Val Tyr 
                165                 170



<210> 2753
<211> 216
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (18)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (56)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (166)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (178)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (186)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (202)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2753
Met Lys Ser Pro Leu Ala Ala Gly Lys Gly His Pro Lys Met Arg Asp
  1               5                  10                  15

Gly Xaa Gly Trp His Pro Gln Asp Thr Gly Leu Arg Arg Gly Pro Ala
             20                  25                  30

Phe Thr Thr Gln Ala Ser Val His Thr Leu Leu Gly Thr Trp Gly His
         35                  40                  45

Ala Cys Trp Ala Asn Pro Pro Xaa Ala Pro Trp His Gly Glu Gly Val
     50                  55                  60

Ala Gly Gly Arg Gln Ser Pro Cys Asp Pro Arg Pro Ala Gly Gln Ala
 65                  70                  75                  80

Ser Asn Ser Ser Pro Ala Leu Pro Ala Ser Ile Arg Gln Pro Gly Met
                 85                  90                  95

Ala Pro Val Ile His Leu Tyr Ile Leu Ile Leu Cys Phe Gln Pro Arg
            100                 105                 110

Val Leu Trp Lys Glu Ile Pro Thr Gly Pro Gly His Ser Ala Val Ser
        115                 120                 125

Ala Pro Thr Ser Ser Lys Gln Trp Ser Trp Thr Pro Arg His Met Leu
    130                 135                 140

Ala Leu Pro Gly Pro Gln Gly Pro Arg Gly Pro Thr Pro Ala Arg Val
145                 150                 155                 160

His Pro Arg Gly Leu Xaa Leu Gly Ser Ser Ser His Trp Lys Gly Glu
                165                 170                 175

Trp Xaa Cys Ser Phe Arg Gly Gly Ser Xaa Leu Arg Ala Trp Arg His
            180                 185                 190

Leu Ser Lys Arg Gly Val Arg Glu Ala Xaa Gly Thr Trp Ala Gly Phe
        195                 200                 205

Thr His Thr Leu Gly Leu Gly Pro 
    210                 215



<210> 2754
<211> 870
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (534)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2754
Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe
  1               5                  10                  15

Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys
             20                  25                  30

Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu
         35                  40                  45

Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met
     50                  55                  60

Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn
 65                  70                  75                  80

Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu
                 85                  90                  95

Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn
            100                 105                 110

Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala
        115                 120                 125

Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr
    130                 135                 140

Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp
145                 150                 155                 160

Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg
                165                 170                 175

Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu
            180                 185                 190

Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys
        195                 200                 205

Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala
    210                 215                 220

Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro
225                 230                 235                 240

Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro
                245                 250                 255

Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His
            260                 265                 270

Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met
        275                 280                 285

Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr
    290                 295                 300

Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr
305                 310                 315                 320

His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu
                325                 330                 335

Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala
            340                 345                 350

Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr
        355                 360                 365

Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys
    370                 375                 380

Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His
385                 390                 395                 400

Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg
                405                 410                 415

Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu
            420                 425                 430

Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg
        435                 440                 445

Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys
    450                 455                 460

Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro
465                 470                 475                 480

Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr
                485                 490                 495

Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys
            500                 505                 510

Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys
        515                 520                 525

Ala Ser Tyr Val Arg Xaa Arg Ser Ile Arg Ser Val Ala Ile Glu Val
    530                 535                 540

Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg
545                 550                 555                 560

Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp
                565                 570                 575

Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser
            580                 585                 590

Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn
        595                 600                 605

Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp
    610                 615                 620

Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn
625                 630                 635                 640

Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg
                645                 650                 655

Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys
            660                 665                 670

Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly
        675                 680                 685

Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys
    690                 695                 700

Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys
705                 710                 715                 720

Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln
                725                 730                 735

Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala
            740                 745                 750

Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn
        755                 760                 765

Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu
    770                 775                 780

Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg
785                 790                 795                 800

Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys
                805                 810                 815

Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly
            820                 825                 830

Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg
        835                 840                 845

Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu
    850                 855                 860

Trp Glu Gly Trp Glu Gly 
865                 870



<210> 2755
<211> 141
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (104)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2755
Met Arg Pro Trp Glu Met Thr Ser Asn Arg Gln Pro Pro Ser Val Arg
  1               5                  10                  15

Pro Ser Gln His His Phe Ser Gly Glu Arg Cys Asn Thr Pro Ala Arg
             20                  25                  30

Asn Arg Arg Ser Pro Pro Val Arg Arg Gln Arg Gly Arg Arg Asp Arg
         35                  40                  45

Leu Ser Arg His Asn Ser Ile Ser Gln Asp Glu Asn Tyr His His Leu
     50                  55                  60

Pro Tyr Ala Gln Gln Gln Ala Ile Gly Ser Leu Glu Pro Ser Thr Leu
 65                  70                  75                  80

Arg Met Tyr Leu Pro Val Cys Tyr Ile Leu Leu Leu Ile His Pro Ser
                 85                  90                  95

Arg Met Gln Ser Trp Leu Thr Xaa His Asp Gln Val Gln Xaa Thr Glu
            100                 105                 110

Cys Leu Gly Asn Thr Glu Ala Glu Ile Leu Trp Gln Phe Glu Ile Phe
        115                 120                 125

Phe Leu Gly Phe Leu Leu Gln Ile Leu Leu Xaa Phe Thr 
    130                 135                 140



<210> 2756
<211> 278
<212> PRT
<213> Homo sapiens

<400> 2756
Met Val Phe Phe Leu Ile Val Val Ile Cys Lys Lys Phe Gln Val Pro
  1               5                  10                  15

Cys Pro Val Glu Ala Ala Leu Ile Ile Asn Glu Thr Ile Asn Thr Thr
             20                  25                  30

Leu Thr Gln Pro Thr Ala Leu Val Pro Ala Leu Ser His Asn Val Thr
         35                  40                  45

Glu Asn Asp Ser Cys Arg Pro His Tyr Phe Ile Phe Asn Ser Gln Thr
     50                  55                  60

Val Tyr Ala Val Pro Ile Leu Ile Phe Ser Phe Val Cys His Pro Ala
 65                  70                  75                  80

Val Leu Pro Ile Tyr Glu Glu Leu Lys Asp Arg Ser Arg Arg Arg Met
                 85                  90                  95

Met Asn Val Ser Lys Ile Ser Phe Phe Ala Met Phe Leu Met Tyr Leu
            100                 105                 110

Leu Ala Ala Leu Phe Gly Tyr Leu Thr Phe Tyr Glu His Val Glu Ser
        115                 120                 125

Glu Leu Leu His Thr Tyr Ser Ser Ile Leu Gly Thr Asp Ile Leu Leu
    130                 135                 140

Leu Ile Val Arg Leu Ala Val Leu Met Ala Val Thr Leu Thr Val Pro
145                 150                 155                 160

Val Val Ile Phe Pro Ile Arg Ser Ser Val Thr His Leu Leu Cys Ala
                165                 170                 175

Ser Lys Asp Phe Ser Trp Trp Arg His Ser Leu Ile Thr Val Ser Ile
            180                 185                 190

Leu Ala Phe Thr Asn Leu Leu Val Ile Phe Val Pro Thr Ile Arg Asp
        195                 200                 205

Ile Phe Gly Phe Ile Gly Ala Ser Ala Ala Ser Met Leu Ile Phe Ile
    210                 215                 220

Leu Pro Ser Ala Phe Tyr Ile Lys Leu Val Lys Lys Glu Pro Met Lys
225                 230                 235                 240

Ser Val Gln Lys Ile Gly Ala Leu Phe Phe Leu Leu Ser Gly Val Leu
                245                 250                 255

Val Met Thr Gly Ser Met Ala Leu Ile Val Leu Asp Trp Val His Asn
            260                 265                 270

Ala Pro Gly Gly Gly His 
        275



<210> 2757
<211> 334
<212> PRT
<213> Homo sapiens

<400> 2757
Met Leu Gly Ile Met Ala Trp Asn Ala Thr Cys Lys Asn Trp Leu Ala
  1               5                  10                  15

Ala Glu Ala Ala Leu Glu Lys Tyr Tyr Leu Ser Ile Phe Tyr Gly Ile
             20                  25                  30

Glu Phe Val Val Gly Val Leu Gly Asn Thr Ile Val Val Tyr Gly Tyr
         35                  40                  45

Ile Phe Ser Leu Lys Asn Trp Asn Ser Ser Asn Ile Tyr Leu Phe Asn
     50                  55                  60

Leu Ser Val Ser Asp Leu Ala Phe Leu Cys Thr Leu Pro Met Leu Ile
 65                  70                  75                  80

Arg Ser Tyr Ala Asn Gly Asn Trp Ile Tyr Gly Asp Val Leu Cys Ile
                 85                  90                  95

Ser Asn Arg Tyr Val Leu His Ala Asn Leu Tyr Thr Ser Ile Leu Phe
            100                 105                 110

Leu Thr Phe Ile Ser Ile Asp Arg Tyr Leu Ile Ile Lys Tyr Pro Phe
        115                 120                 125

Arg Glu His Leu Leu Gln Lys Lys Glu Phe Ala Ile Leu Ile Ser Leu
    130                 135                 140

Ala Ile Trp Val Leu Val Thr Leu Glu Leu Leu Pro Ile Leu Pro Leu
145                 150                 155                 160

Ile Asn Pro Val Ile Thr Asp Asn Gly Thr Thr Cys Asn Asp Phe Ala
                165                 170                 175

Ser Ser Gly Asp Pro Asn Tyr Asn Leu Ile Tyr Ser Met Cys Leu Thr
            180                 185                 190

Leu Leu Gly Phe Leu Ile Pro Leu Phe Val Met Cys Phe Phe Tyr Tyr
        195                 200                 205

Lys Ile Ala Leu Phe Leu Lys Gln Arg Asn Arg Gln Val Ala Thr Ala
    210                 215                 220

Leu Pro Leu Glu Lys Pro Leu Asn Leu Val Ile Met Ala Val Val Ile
225                 230                 235                 240

Phe Ser Val Leu Phe Thr Pro Tyr His Val Met Arg Asn Val Arg Ile
                245                 250                 255

Ala Ser Arg Leu Gly Ser Trp Lys Gln Tyr Gln Cys Thr Gln Val Val
            260                 265                 270

Ile Asn Ser Phe Tyr Ile Val Thr Arg Pro Leu Ala Phe Leu Asn Ser
        275                 280                 285

Val Ile Asn Pro Val Phe Tyr Phe Leu Leu Gly Asp His Phe Arg Asp
    290                 295                 300

Met Leu Met Asn Gln Leu Arg His Asn Phe Lys Ser Leu Thr Ser Phe
305                 310                 315                 320

Ser Arg Trp Ala His Glu Leu Leu Leu Ser Phe Arg Glu Lys 
                325                 330



<210> 2758
<211> 390
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (43)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (377)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2758
Met Ile Leu Asn Thr Ile Tyr Glu Lys Val Ala Ile Met Ile Thr Asn
  1               5                  10                  15

Phe Glu Leu Pro Arg Thr Gln Thr Asp Tyr Glu Asn Ser Leu Thr Met
             20                  25                  30

Lys Met Phe Leu Phe Gln Phe Val Asn Tyr Xaa Ser Ser Cys Phe Tyr
         35                  40                  45

Ile Ala Phe Phe Lys Gly Lys Phe Val Gly Tyr Pro Gly Asp Pro Val
     50                  55                  60

Tyr Trp Leu Gly Lys Tyr Arg Asn Glu Glu Cys Asp Pro Gly Gly Cys
 65                  70                  75                  80

Leu Leu Glu Leu Thr Thr Gln Leu Thr Ile Ile Met Gly Gly Lys Ala
                 85                  90                  95

Ile Trp Asn Asn Ile Gln Glu Val Leu Leu Pro Trp Ile Met Asn Leu
            100                 105                 110

Ile Gly Arg Phe His Arg Val Ser Gly Ser Glu Lys Ile Thr Pro Arg
        115                 120                 125

Trp Glu Gln Asp Tyr His Leu Gln Pro Met Gly Lys Leu Gly Leu Phe
    130                 135                 140

Tyr Glu Tyr Leu Glu Met Ile Ile Gln Phe Gly Phe Val Thr Leu Phe
145                 150                 155                 160

Val Ala Ser Phe Pro Leu Ala Pro Leu Leu Ala Leu Val Asn Asn Ile
                165                 170                 175

Leu Glu Ile Arg Val Asp Ala Trp Lys Leu Thr Thr Gln Phe Arg Arg
            180                 185                 190

Leu Val Pro Glu Lys Ala Gln Asp Ile Gly Ala Trp Gln Pro Ile Met
        195                 200                 205

Gln Gly Ile Ala Ile Leu Ala Val Val Thr Asn Ala Met Ile Ile Ala
    210                 215                 220

Phe Thr Ser Asp Met Ile Pro Arg Leu Val Tyr Tyr Trp Ser Phe Ser
225                 230                 235                 240

Val Pro Pro Tyr Gly Asp His Thr Ser Tyr Thr Met Glu Gly Tyr Ile
                245                 250                 255

Asn Asn Thr Leu Ser Ile Phe Lys Val Ala Asp Phe Lys Asn Lys Ser
            260                 265                 270

Lys Gly Asn Pro Tyr Ser Asp Leu Gly Asn His Thr Thr Cys Arg Tyr
        275                 280                 285

Arg Asp Phe Arg Tyr Pro Pro Gly His Pro Gln Glu Tyr Lys His Asn
    290                 295                 300

Ile Tyr Tyr Trp His Val Ile Ala Ala Lys Leu Ala Phe Ile Ile Val
305                 310                 315                 320

Met Glu His Val Ile Tyr Ser Val Lys Phe Phe Ile Ser Tyr Ala Ile
                325                 330                 335

Pro Asp Val Ser Lys Arg Thr Lys Ser Lys Ile Gln Arg Glu Lys Tyr
            340                 345                 350

Leu Thr Gln Lys Leu Leu His Glu Asn His Leu Lys Asp Met Thr Lys
        355                 360                 365

Asn Met Gly Val Ile Ala Glu Arg Xaa Ile Glu Ala Val Asp Asn Asn
    370                 375                 380

Leu Arg Pro Lys Ser Glu 
385                 390



<210> 2759
<211> 101
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (48)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2759
Met Ser Phe Ala Gly Pro Arg Ser Asp Leu Lys Leu Ser Trp Ala Cys
  1               5                  10                  15

Cys His Trp Val Leu Pro Leu Gln Arg Leu Pro Arg Ser Pro Val Ala
             20                  25                  30

Pro Gln Asp Pro Gly Ser Gln Leu Leu Leu Gly Asp Val His Cys Xaa
         35                  40                  45

Arg Arg Pro Cys Ser Leu Ser Thr Leu Gly Arg Asn Ser Gly Phe Ser
     50                  55                  60

Glu Pro Gly Ala Tyr Arg Arg Arg Gln Glu Leu Ile Phe Val Leu Gly
 65                  70                  75                  80

Leu Gly Phe Leu Cys Pro Gln Gly Thr Val Leu Phe Leu Phe Thr Pro
                 85                  90                  95

Leu Leu Tyr Leu Leu 
            100



<210> 2760
<211> 450
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (140)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2760
Met Glu Glu Pro Gln Lys Ser Tyr Val Asn Thr Met Asp Leu Glu Arg
  1               5                  10                  15

Asp Glu Pro Leu Lys Ser Thr Gly Pro Gln Ile Ser Val Ser Glu Phe
             20                  25                  30

Ser Cys His Cys Cys Tyr Asp Ile Leu Val Asn Pro Thr Thr Leu Asn
         35                  40                  45

Cys Gly His Ser Phe Cys Arg His Cys Leu Ala Leu Trp Trp Ala Ser
     50                  55                  60

Ser Lys Lys Thr Glu Cys Pro Glu Cys Arg Glu Lys Trp Glu Gly Phe
 65                  70                  75                  80

Pro Lys Val Ser Ile Leu Leu Arg Asp Ala Ile Glu Lys Leu Phe Pro
                 85                  90                  95

Asp Ala Ile Arg Leu Arg Phe Glu Asp Ile Gln Gln Asn Asn Asp Ile
            100                 105                 110

Val Gln Ser Leu Ala Ala Phe Gln Lys Tyr Gly Asn Asp Gln Ile Pro
        115                 120                 125

Leu Ala Pro Asn Thr Gly Arg Ala Asn Gln Gln Xaa Gly Gly Gly Phe
    130                 135                 140

Phe Ser Gly Val Leu Thr Ala Leu Thr Gly Val Ala Val Val Leu Leu
145                 150                 155                 160

Val Tyr His Trp Ser Ser Arg Glu Ser Glu His Asp Leu Leu Val His
                165                 170                 175

Lys Ala Val Ala Lys Trp Thr Ala Glu Glu Val Val Leu Trp Leu Glu
            180                 185                 190

Gln Leu Gly Pro Trp Ala Ser Leu Tyr Arg Glu Arg Phe Leu Ser Glu
        195                 200                 205

Arg Val Asn Gly Arg Leu Leu Leu Thr Leu Thr Glu Glu Glu Phe Ser
    210                 215                 220

Lys Thr Pro Tyr Thr Ile Glu Asn Ser Ser His Arg Arg Ala Ile Leu
225                 230                 235                 240

Met Glu Leu Glu Arg Val Lys Ala Leu Gly Val Lys Pro Pro Gln Asn
                245                 250                 255

Leu Trp Glu Tyr Lys Ala Val Asn Pro Gly Arg Ser Leu Phe Leu Leu
            260                 265                 270

Tyr Ala Leu Lys Ser Ser Pro Arg Leu Ser Leu Leu Tyr Leu Tyr Leu
        275                 280                 285

Phe Asp Tyr Thr Asp Thr Phe Leu Pro Phe Ile His Thr Ile Cys Pro
    290                 295                 300

Leu Gln Glu Asp Ser Ser Gly Glu Asp Ile Val Thr Lys Leu Leu Asp
305                 310                 315                 320

Leu Lys Glu Pro Thr Trp Lys Gln Trp Arg Glu Phe Leu Val Lys Tyr
                325                 330                 335

Ser Phe Leu Pro Tyr Gln Leu Ile Ala Glu Phe Ala Trp Asp Trp Leu
            340                 345                 350

Glu Val His Tyr Trp Thr Ser Arg Phe Leu Ile Ile Asn Ala Met Leu
        355                 360                 365

Leu Ser Val Leu Glu Leu Phe Ser Phe Trp Arg Ile Trp Ser Arg Ser
    370                 375                 380

Glu Leu Lys Thr Val Pro Gln Arg Met Trp Ser His Phe Trp Lys Val
385                 390                 395                 400

Ser Thr Gln Gly Leu Phe Val Ala Met Phe Trp Pro Leu Ile Pro Gln
                405                 410                 415

Phe Val Cys Asn Cys Leu Phe Tyr Trp Ala Leu Tyr Phe Asn Pro Ile
            420                 425                 430

Ile Asn Ile Asp Leu Val Val Lys Glu Leu Arg Arg Leu Glu Thr Gln
        435                 440                 445

Val Leu 
    450



<210> 2761
<211> 435
<212> PRT
<213> Homo sapiens

<400> 2761
Met Asp Cys Ser Ser Tyr Ser Thr Tyr Cys Tyr Arg Cys Asp Asp Phe
  1               5                  10                  15

Val Val Asn Asp Thr Lys Leu Gly Leu Val Gln Lys Val Arg Glu His
             20                  25                  30

Leu Gln Asn Leu Glu Asn Ser Ala Phe Thr Ala Asp Arg His Lys Lys
         35                  40                  45

Arg Lys Leu Leu Glu Asn Ser Thr Leu Asn Ser Lys Leu Leu Lys Val
     50                  55                  60

Asn Gly Ser Thr Thr Ala Ile Cys Ala Thr Gly Leu Arg Asn Leu Gly
 65                  70                  75                  80

Asn Thr Cys Phe Met Asn Ala Ile Leu Gln Ser Leu Ser Asn Ile Glu
                 85                  90                  95

Gln Phe Cys Cys Tyr Phe Lys Glu Leu Pro Ala Val Glu Leu Arg Asn
            100                 105                 110

Gly Lys Thr Ala Gly Arg Arg Thr Tyr His Thr Arg Ser Gln Gly Asp
        115                 120                 125

Asn Asn Val Ser Leu Val Glu Glu Phe Arg Lys Thr Leu Cys Ala Leu
    130                 135                 140

Trp Gln Gly Ser Gln Thr Ala Phe Ser Pro Glu Ser Leu Phe Tyr Val
145                 150                 155                 160

Val Trp Lys Ile Met Pro Asn Phe Arg Gly Tyr Gln Gln Gln Asp Ala
                165                 170                 175

His Glu Phe Met Arg Tyr Leu Leu Asp His Leu His Leu Glu Leu Gln
            180                 185                 190

Gly Gly Phe Asn Gly Val Ser Arg Ser Ala Ile Leu Gln Glu Asn Ser
        195                 200                 205

Thr Leu Ser Ala Ser Asn Lys Cys Cys Ile Asn Gly Ala Ser Thr Val
    210                 215                 220

Val Thr Ala Ile Phe Gly Gly Ile Leu Gln Asn Glu Val Asn Cys Leu
225                 230                 235                 240

Ile Cys Gly Thr Glu Ser Arg Lys Phe Asp Pro Phe Leu Asp Leu Ser
                245                 250                 255

Leu Asp Ile Pro Ser Gln Phe Arg Ser Lys Arg Ser Lys Asn Gln Glu
            260                 265                 270

Asn Gly Pro Val Cys Ser Leu Arg Asp Cys Leu Arg Ser Phe Thr Asp
        275                 280                 285

Leu Glu Glu Leu Asp Glu Thr Glu Leu Tyr Met Cys His Lys Cys Lys
    290                 295                 300

Lys Lys Gln Lys Ser Thr Lys Lys Phe Trp Ile Gln Lys Leu Pro Lys
305                 310                 315                 320

Val Leu Cys Leu His Leu Lys Arg Phe His Trp Thr Ala Tyr Leu Arg
                325                 330                 335

Asn Lys Val Asp Thr Tyr Val Glu Phe Pro Leu Arg Gly Leu Asp Met
            340                 345                 350

Lys Cys Tyr Leu Leu Glu Pro Glu Asn Ser Gly Pro Glu Ser Cys Leu
        355                 360                 365

Tyr Asp Leu Ala Ala Val Val Val His His Gly Ser Gly Val Gly Ser
    370                 375                 380

Gly His Tyr Thr Ala Tyr Ala Thr His Glu Gly Arg Trp Phe His Phe
385                 390                 395                 400

Asn Asp Ser Thr Val Thr Leu Thr Asp Glu Glu Thr Val Val Lys Ala
                405                 410                 415

Lys Ala Tyr Ile Leu Phe Tyr Val Glu His Gln Ala Lys Ala Gly Ser
            420                 425                 430

Asp Lys Leu 
        435



<210> 2762
<211> 119
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (117)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2762
Met Lys Glu Ala His His Gln Ala His Gln Val Pro Gly Glu Arg Val
  1               5                  10                  15

Asp Ile Gly Pro Gln Ser His Leu Met Lys Val Ala Leu Cys Pro Ser
             20                  25                  30

Leu Ala Trp Leu Ser Phe Ser Ser Leu Asn Glu Asp Asp Asp Asp Gln
         35                  40                  45

Pro Arg Arg Thr His Gln Arg Thr Asp Leu Thr Thr Trp Ala Met Arg
     50                  55                  60

Ser Phe Gly Glu Asn Asp Ala Leu Lys Thr Cys Ser Val Cys Ile Thr
 65                  70                  75                  80

Glu Tyr Gln Lys Ala Thr Asn Phe Val Asn Tyr Leu Val Pro Met Ser
                 85                  90                  95

Thr Met Ser Thr Ala Ser Ile Ala Gly Tyr Leu Arg Ile Leu Pro Val
            100                 105                 110

Leu Phe Val Ala Xaa Gln Ser 
        115



<210> 2763
<211> 115
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (87)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (112)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2763
Met Ser His Pro Gly Ala Val Asp Ile Val Ala Ile Met Ile Gly Asn
  1               5                  10                  15

Leu Lys Gly Thr Lys Ile Leu Gln Ser Ile Gln Arg Gly Ile Gln Val
             20                  25                  30

Thr Met Val Ile Glu Val Gly Lys Lys His Gly Pro Trp Val Asn His
         35                  40                  45

Tyr Ser Ile Phe Phe Val Ser Val Ser Phe Phe Ile Ile Thr Ala Ala
     50                  55                  60

Thr Val Gly Tyr Phe Ile Phe Tyr Ser Ala Arg Arg Leu Arg Asn Ala
 65                  70                  75                  80

Arg Ala Gln Ser Arg Lys Xaa Arg Gln Leu Lys Ala Asp Ala Lys Lys
                 85                  90                  95

Ala Ile Gly Arg Leu Gln Leu Arg Thr Leu Lys Gln Gly Asp Lys Xaa
            100                 105                 110

Asn Trp Pro 
        115



<210> 2764
<211> 400
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2764
Met Ala Trp Arg Arg Arg Glu Ala Xaa Val Gly Ala Arg Gly Val Leu
  1               5                  10                  15

Ala Leu Ala Leu Leu Ala Leu Ala Leu Cys Val Pro Gly Ala Arg Gly
             20                  25                  30

Arg Ala Leu Glu Trp Phe Ser Ala Val Val Asn Ile Glu Tyr Val Asp
         35                  40                  45

Pro Gln Thr Asn Leu Thr Val Trp Ser Val Ser Glu Ser Gly Arg Phe
     50                  55                  60

Gly Asp Ser Ser Pro Lys Glu Gly Ala His Gly Leu Val Gly Val Pro
 65                  70                  75                  80

Trp Ala Pro Gly Gly Asp Leu Glu Gly Cys Ala Pro Asp Thr Arg Phe
                 85                  90                  95

Phe Val Pro Glu Pro Gly Gly Arg Gly Ala Ala Pro Trp Val Ala Leu
            100                 105                 110

Val Ala Arg Gly Gly Cys Thr Phe Lys Asp Lys Val Leu Val Ala Ala
        115                 120                 125

Arg Arg Asn Ala Ser Ala Val Val Leu Tyr Asn Glu Glu Arg Tyr Gly
    130                 135                 140

Asn Ile Thr Leu Pro Met Ser His Ala Gly Thr Gly Asn Ile Val Val
145                 150                 155                 160

Ile Met Ile Ser Tyr Pro Lys Gly Arg Glu Ile Leu Glu Leu Val Gln
                165                 170                 175

Lys Gly Ile Pro Val Thr Met Thr Ile Gly Val Gly Thr Arg His Val
            180                 185                 190

Gln Glu Phe Ile Ser Gly Gln Ser Val Val Phe Val Ala Ile Ala Phe
        195                 200                 205

Ile Thr Met Met Ile Ile Ser Leu Ala Trp Leu Ile Phe Tyr Tyr Ile
    210                 215                 220

Gln Arg Phe Leu Tyr Thr Gly Ser Gln Ile Gly Ser Gln Ser His Arg
225                 230                 235                 240

Lys Glu Thr Lys Lys Val Ile Gly Gln Leu Leu Leu His Thr Val Lys
                245                 250                 255

His Gly Glu Lys Gly Ile Asp Val Asp Ala Glu Asn Cys Ala Val Cys
            260                 265                 270

Ile Glu Asn Phe Lys Val Lys Asp Ile Ile Arg Ile Leu Pro Cys Lys
        275                 280                 285

His Ile Phe His Arg Ile Cys Ile Asp Pro Trp Leu Leu Asp His Arg
    290                 295                 300

Thr Cys Pro Met Cys Lys Leu Asp Val Ile Lys Ala Leu Gly Tyr Trp
305                 310                 315                 320

Gly Glu Pro Gly Asp Val Gln Glu Met Pro Ala Pro Glu Ser Pro Pro
                325                 330                 335

Gly Arg Asp Pro Ala Ala Asn Leu Ser Leu Ala Leu Pro Asp Asp Asp
            340                 345                 350

Gly Ser Asp Glu Ser Ser Pro Pro Ser Ala Ser Pro Ala Glu Ser Glu
        355                 360                 365

Pro Gln Cys Asp Pro Ser Phe Lys Gly Asp Ala Gly Glu Asn Thr Ala
    370                 375                 380

Leu Leu Glu Ala Gly Arg Ser Asp Ser Arg His Gly Gly Pro Ile Ser
385                 390                 395                 400






<210> 2765
<211> 419
<212> PRT
<213> Homo sapiens

<400> 2765
Met Ser Cys Ala Gly Arg Ala Gly Pro Ala Arg Leu Ala Ala Leu Ala
  1               5                  10                  15

Leu Leu Thr Cys Ser Leu Trp Pro Ala Arg Ala Asp Asn Ala Ser Gln
             20                  25                  30

Glu Tyr Tyr Thr Ala Leu Ile Asn Val Thr Val Gln Glu Pro Gly Arg
         35                  40                  45

Gly Ala Pro Leu Thr Phe Arg Ile Asp Arg Gly Arg Tyr Gly Leu Asp
     50                  55                  60

Ser Pro Lys Ala Glu Val Arg Gly Gln Val Leu Ala Pro Leu Pro Leu
 65                  70                  75                  80

His Gly Val Ala Asp His Leu Gly Cys Asp Pro Gln Thr Arg Phe Phe
                 85                  90                  95

Val Pro Pro Asn Ile Lys Gln Trp Ile Ala Leu Leu Gln Arg Gly Asn
            100                 105                 110

Cys Thr Phe Lys Glu Lys Ile Ser Arg Ala Ala Phe His Asn Ala Val
        115                 120                 125

Ala Val Val Ile Tyr Asn Asn Lys Ser Lys Glu Glu Pro Val Thr Met
    130                 135                 140

Thr His Pro Gly Thr Gly Asp Ile Ile Ala Val Met Ile Thr Glu Leu
145                 150                 155                 160

Arg Gly Lys Asp Ile Leu Ser Tyr Leu Glu Lys Asn Ile Ser Val Gln
                165                 170                 175

Met Thr Ile Ala Val Gly Thr Arg Met Pro Pro Lys Asn Phe Ser Arg
            180                 185                 190

Gly Ser Leu Val Phe Val Ser Ile Ser Phe Ile Val Leu Met Ile Ile
        195                 200                 205

Ser Ser Ala Trp Leu Ile Phe Tyr Phe Ile Gln Lys Ile Arg Tyr Thr
    210                 215                 220

Asn Ala Arg Asp Arg Asn Gln Arg Arg Leu Gly Asp Ala Ala Lys Lys
225                 230                 235                 240

Ala Ile Ser Lys Leu Thr Thr Arg Thr Val Lys Lys Gly Asp Lys Glu
                245                 250                 255

Thr Asp Pro Asp Phe Asp His Cys Ala Val Cys Ile Glu Ser Tyr Lys
            260                 265                 270

Gln Asn Asp Val Val Arg Ile Leu Pro Cys Lys His Val Phe His Lys
        275                 280                 285

Ser Cys Val Asp Pro Trp Leu Ser Glu His Cys Thr Cys Pro Met Cys
    290                 295                 300

Lys Leu Asn Ile Leu Lys Ala Leu Gly Ile Val Pro Asn Leu Pro Cys
305                 310                 315                 320

Thr Asp Asn Val Ala Phe Asp Met Glu Arg Leu Thr Arg Thr Gln Ala
                325                 330                 335

Val Asn Arg Arg Ser Ala Leu Gly Asp Leu Ala Gly Asp Asn Ser Leu
            340                 345                 350

Gly Leu Glu Pro Leu Arg Thr Ser Gly Ile Ser Pro Leu Pro Gln Asp
        355                 360                 365

Gly Glu Leu Thr Pro Arg Thr Gly Glu Ile Asn Ile Ala Val Thr Lys
    370                 375                 380

Glu Trp Phe Ile Ile Ala Ser Phe Gly Leu Leu Ser Ala Leu Thr Leu
385                 390                 395                 400

Cys Tyr Met Ile Ile Arg Ala Thr Ala Ser Leu Asn Ala Asn Glu Val
                405                 410                 415

Glu Trp Phe 




<210> 2766
<211> 199
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (8)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (9)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2766
Met Met Met Trp Ser Trp Ser Xaa Xaa Gly Arg Lys Gln Lys Glu Gly
  1               5                  10                  15

Ser Lys Asp Tyr Gln Leu Val Thr Trp Ser Arg Asp Gln Thr Leu Arg
             20                  25                  30

Met Trp Arg Val Asp Ser Gln Met Gln Arg Leu Cys Ala Asn Asp Ile
         35                  40                  45

Leu Asp Gly Val Asp Glu Phe Ile Glu Xaa Ile Ser Leu Leu Pro Glu
     50                  55                  60

Pro Glu Lys Thr Leu His Thr Glu Asp Thr Asp His Gln His Thr Ala
 65                  70                  75                  80

Ser His Gly Glu Glu Glu Ala Leu Lys Glu Asp Pro Pro Arg Asn Leu
                 85                  90                  95

Leu Glu Glu Arg Lys Ser Asp Gln Leu Gly Leu Pro Gln Thr Leu Gln
            100                 105                 110

Gln Glu Phe Ser Leu Ile Asn Val Gln Ile Arg Asn Val Asn Val Glu
        115                 120                 125

Met Asp Ala Ala Asp Arg Ser Cys Thr Val Ser Val His Cys Ser Asn
    130                 135                 140

His Arg Val Lys Met Leu Val Lys Phe Pro Ala Gln Tyr Pro Asn Asn
145                 150                 155                 160

Ala Ala Pro Ser Phe Gln Phe Ile Asn Pro Thr Thr Ile Thr Ser Thr
                165                 170                 175

Met Lys Ala Lys Leu Leu Lys Val Gly Val Trp Val Pro Lys Phe Ser
            180                 185                 190

Leu Leu Phe Cys Ile Ile Val 
        195



<210> 2767
<211> 257
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (139)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (141)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (234)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (238)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2767
Met Asp Thr Ser Thr Val Gly Val Leu Leu Ala Ala Lys Met Ser Gln
  1               5                  10                  15

Tyr Ala Asn Leu Leu Ala Ala Gln Gly Ser Ile Ala Ala Ala Leu Ala
             20                  25                  30

Phe Leu Pro Asp Asn Thr Asn Gln Pro Asn Ile Met Gln Leu Arg Asp
         35                  40                  45

Arg Leu Cys Arg Ala Gln Gly Glu Pro Val Ala Gly His Glu Ser Pro
     50                  55                  60

Lys Ile Pro Tyr Glu Lys Gln Gln Leu Pro Lys Gly Arg Pro Gly Pro
 65                  70                  75                  80

Val Ala Gly His His Gln Met Pro Arg Val Gln Thr Gln Gln Tyr Tyr
                 85                  90                  95

Pro His Gly Glu Asn Pro Pro Pro Pro Gly Phe Ile Met His Gly Asn
            100                 105                 110

Val Asn Pro Asn Ala Ala Gly Gln Leu Pro Thr Ser Pro Gly His Met
        115                 120                 125

His Thr Gln Val Pro Pro Tyr Pro Gln Ala Xaa Ala Xaa Ile Asn Gln
    130                 135                 140

Pro Ser Arg Ile Pro Ser Glu Xaa Gly Gly Gln Gln Cys Ile Asp Leu
145                 150                 155                 160

Ser Ser Leu Leu Leu Leu Leu Leu Gln Xaa Leu Thr Leu Thr Pro Leu
                165                 170                 175

Thr Tyr Leu Leu Leu Leu Pro Ile Leu Gly Ser Leu Ser Cys Thr Gln
            180                 185                 190

His Ser Thr Arg Pro Leu His Leu Pro Pro Ala Leu Leu Leu Leu Ser
        195                 200                 205

Leu Leu Pro Leu Pro Leu Glu His Pro Ser Ser Met Ala Asp Gln Glu
    210                 215                 220

Leu His His His Leu Gln Leu Met His Xaa Leu Leu Glu Xaa Gln Val
225                 230                 235                 240

His Cys Leu Leu Pro Val Ser Cys Leu Arg Pro Lys Glu Gln Val Cys
                245                 250                 255

Ala 




<210> 2768
<211> 357
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (118)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (297)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2768
Met Ser Thr Leu Glu Ser Val Thr Tyr Leu Pro Glu Lys Gly Leu Tyr
  1               5                  10                  15

Cys Gln Arg Leu Pro Ser Ser Arg Thr His Gly Gly Thr Glu Ser Leu
             20                  25                  30

Lys Gly Lys Asn Thr Glu Asn Met Gly Phe Tyr Gly Thr Leu Lys Met
         35                  40                  45

Ile Phe Tyr Lys Met Lys Arg Lys Leu Asp His Gly Ser Glu Val Arg
     50                  55                  60

Ser Phe Ser Leu Gly Lys Lys Pro Cys Lys Val Ser Glu Tyr Thr Ser
 65                  70                  75                  80

Thr Thr Gly Leu Val Pro Cys Ser Ala Thr Pro Thr Thr Phe Gly Asp
                 85                  90                  95

Leu Arg Ala Ala Asn Gly Gln Gly Gln Gln Arg Arg Arg Ile Thr Ser
            100                 105                 110

Val Gln Pro Pro Thr Xaa Leu Gln Glu Trp Leu Lys Met Phe Gln Ser
        115                 120                 125

Trp Ser Gly Pro Glu Lys Leu Leu Ala Leu Asp Glu Leu Ile Asp Ser
    130                 135                 140

Cys Glu Pro Thr Gln Val Lys His Met Met Gln Val Ile Glu Pro Gln
145                 150                 155                 160

Phe Gln Arg Asp Phe Ile Ser Leu Leu Pro Lys Glu Leu Ala Leu Tyr
                165                 170                 175

Val Leu Ser Phe Leu Glu Pro Lys Asp Leu Leu Gln Ala Ala Gln Thr
            180                 185                 190

Cys Arg Tyr Trp Arg Ile Leu Ala Glu Asp Asn Leu Leu Trp Arg Glu
        195                 200                 205

Lys Cys Lys Glu Glu Gly Ile Asp Glu Pro Leu His Ile Lys Arg Arg
    210                 215                 220

Lys Val Ile Lys Pro Gly Phe Ile His Ser Pro Trp Lys Ser Ala Tyr
225                 230                 235                 240

Ile Arg Gln His Arg Ile Asp Thr Asn Trp Arg Arg Gly Glu Leu Lys
                245                 250                 255

Ser Pro Lys Val Leu Lys Gly His Asp Asp His Val Ile Thr Cys Leu
            260                 265                 270

Gln Phe Cys Gly Asn Arg Ile Val Ser Gly Ser Asp Asp Asn Thr Leu
        275                 280                 285

Lys Val Trp Ser Ala Val Thr Gly Xaa Cys Leu Arg Thr Leu Val Gly
    290                 295                 300

His Thr Gly Gly Val Trp Ser Ser Gln Met Arg Asp Asn Ile Ile Ile
305                 310                 315                 320

Ser Gly Ser Thr Asp Arg Thr Leu Lys Val Trp Asn Ala Glu Thr Gly
                325                 330                 335

Glu Cys Ile His Thr Leu Tyr Gly His Thr Ser Thr Val Arg Cys Met
            340                 345                 350

His Leu His Glu Lys 
        355



<210> 2769
<211> 155
<212> PRT
<213> Homo sapiens

<400> 2769
Met Glu Phe Ala Gln Ile Ser Arg Val Lys Thr Phe Gln Glu Asn Leu
  1               5                  10                  15

Ser Ala Phe Lys Arg Asp Pro Gln Ile Asn Ile Leu Leu Leu Pro Leu
             20                  25                  30

His Thr Gly Ser Asn Gly Leu Thr Ile Ile Glu Ala Thr His Val Leu
         35                  40                  45

Leu Val Glu Pro Ile Leu Asn Pro Ala His Glu Leu Gln Ala Ile Gly
     50                  55                  60

Arg Val His Arg Ile Gly Gln Thr Lys Pro Thr Ile Val His Arg Phe
 65                  70                  75                  80

Leu Ile Lys Ala Thr Ile Glu Glu Arg Met Gln Ala Met Leu Lys Thr
                 85                  90                  95

Ala Glu Arg Arg Phe Phe Glu Glu Gln Ala Leu Phe Cys Phe His Asp
            100                 105                 110

Ile Thr Pro Phe Ser His Pro Trp Ser Leu Thr Thr Ala Ile Leu Gln
        115                 120                 125

Leu Arg Asp Leu Val Ile Cys Glu Leu Phe Phe Ile Tyr Phe Lys Asn
    130                 135                 140

Phe Leu Ile Cys Phe Leu Ser Ser Phe Ser Ile 
145                 150                 155



<210> 2770
<211> 291
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (16)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2770
Met Ile Asp Ser Met His Gln Ser Trp Leu Pro Arg Val Val Ala Xaa
  1               5                  10                  15

Ala Phe Gln Ser Glu Asp Pro Ala Asp Pro Cys Ala Leu Leu Gln Arg
             20                  25                  30

Arg Gln Ala Gln Ala Val Thr Ala Ala Ser Thr Cys Cys Pro Gln Met
         35                  40                  45

Pro Leu Gln Lys Leu Leu Phe Ser Ala Thr Leu Thr Gln Asn Pro Glu
     50                  55                  60

Lys Leu Gln Gln Leu Gly Leu His Gln Pro Arg Leu Phe Ser Thr Gly
 65                  70                  75                  80

Leu Ala His Arg Gly Leu Glu Asp Thr Asp Gly Asp Gly Asp Ser Gly
                 85                  90                  95

Lys Tyr Ala Phe Pro Val Gly Leu Thr His His Tyr Val Pro Cys Ser
            100                 105                 110

Leu Ser Ser Lys Pro Leu Val Val Leu His Leu Val Leu Glu Met Gly
        115                 120                 125

Phe Ser Arg Val Leu Cys Phe Thr Asn Ser Arg Glu Asn Ser His Arg
    130                 135                 140

Leu Phe Leu Leu Val Gln Ala Phe Gly Gly Val Asp Val Ala Glu Phe
145                 150                 155                 160

Ser Ser Arg Tyr Gly Pro Gly Gln Arg Arg Met Ile Leu Lys Gln Phe
                165                 170                 175

Glu Gln Gly Lys Ile Gln Leu Leu Ile Ser Thr Asp Ala Thr Ala Arg
            180                 185                 190

Gly Ile Asp Val Gln Gly Val Glu Leu Val Val Asn Tyr Asp Ala Pro
        195                 200                 205

Gln Tyr Leu Arg Thr Tyr Val His Arg Val Gly Arg Thr Ala Arg Ala
    210                 215                 220

Gly Lys Thr Gly Gln Ala Phe Thr Leu Leu Leu Lys Val Gln Glu Arg
225                 230                 235                 240

Arg Phe Leu Arg Met Leu Thr Glu Ala Gly Ala Pro Glu Leu Gln Arg
                245                 250                 255

His Glu Leu Ser Ser Lys Leu Leu Gln Pro Leu Val Pro Arg Tyr Glu
            260                 265                 270

Glu Ala Leu Ser Gln Leu Glu Glu Ser Val Lys Glu Glu Arg Lys Gln
        275                 280                 285

Arg Ala Ala 
    290



<210> 2771
<211> 301
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (58)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2771
Met Ala Leu Gln Asn Glu Lys Asn Ser Arg Tyr Leu Leu Arg Asp Trp
  1               5                  10                  15

Lys Pro Glu Asn Pro Ala Phe Trp Glu Asn Lys Gly Lys His Ile Ala
             20                  25                  30

Arg Arg Asn Leu Trp Ile Ser Val Ser Cys Leu Leu Leu Ala Phe Cys
         35                  40                  45

Val Trp Met Xaa Phe Ser Ala Val Thr Xaa Asn Leu Asn Lys Ile Gly
     50                  55                  60

Phe Asn Phe Thr Thr Asp Gln Leu Phe Leu Leu Thr Ala Leu Pro Ser
 65                  70                  75                  80

Val Ser Gly Ala Leu Leu Arg Val Pro Tyr Ser Phe Met Val Pro Ile
                 85                  90                  95

Phe Gly Gly Arg Arg Trp Thr Val Phe Ser Thr Ala Ile Leu Ile Ile
            100                 105                 110

Pro Cys Val Trp Leu Gly Ile Ala Val Gln Asn Pro Asn Thr Pro Phe
        115                 120                 125

Gly Ile Phe Ile Val Ile Ala Leu Leu Cys Gly Phe Ala Gly Ala Asn
    130                 135                 140

Phe Ala Ser Ser Met Gly Asn Ile Ser Phe Phe Phe Pro Lys Ala Lys
145                 150                 155                 160

Gln Gly Ser Ala Leu Gly Ile Asn Gly Gly Leu Gly Asn Leu Gly Val
                165                 170                 175

Ser Val Met Gln Leu Val Ala Pro Leu Val Ile Phe Val Pro Val Phe
            180                 185                 190

Ala Phe Leu Gly Val Asn Gly Val Pro Gln Ala Asp Gly Ser Val Met
        195                 200                 205

Ser Leu Ala Asn Ala Ala Trp Ile Trp Val Pro Leu Leu Ala Ile Ala
    210                 215                 220

Thr Ile Ala Ala Trp Ser Gly Met Asn Asp Ile Ala Ser Ser Arg Ala
225                 230                 235                 240

Ser Ile Ala Asp Gln Leu Pro Val Leu Gln Arg Leu His Leu Trp Leu
                245                 250                 255

Leu Ser Leu Leu Tyr Leu Ala His Phe Gly Ser Phe Ile Gly Phe Ser
            260                 265                 270

Ala Gly Phe Ala Met Leu Ala Lys Thr Gln Phe Pro Asp Val Asn Ile
        275                 280                 285

Leu Arg Leu Ala Phe Phe Gly Pro Phe Ile Gly Ala Ile 
    290                 295                 300



<210> 2772
<211> 301
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (208)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2772
Met Phe Ser His Leu Pro Phe Asp Cys Val Leu Leu Leu Leu Leu Leu
  1               5                  10                  15

Leu Leu Thr Arg Ser Ser Glu Val Glu Tyr Arg Ala Glu Val Gly Gln
             20                  25                  30

Asn Ala Tyr Leu Pro Cys Phe Tyr Thr Pro Ala Ala Pro Gly Asn Leu
         35                  40                  45

Val Pro Val Cys Trp Gly Lys Gly Ala Cys Pro Val Phe Glu Cys Gly
     50                  55                  60

Asn Val Val Leu Arg Thr Asp Glu Arg Asp Val Asn Tyr Trp Thr Ser
 65                  70                  75                  80

Arg Tyr Trp Leu Asn Gly Asp Phe Arg Lys Gly Asp Val Ser Leu Thr
                 85                  90                  95

Ile Glu Asn Val Thr Leu Ala Asp Ser Gly Ile Tyr Cys Cys Arg Ile
            100                 105                 110

Gln Ile Pro Gly Ile Met Asn Asp Glu Lys Phe Asn Leu Lys Leu Val
        115                 120                 125

Ile Lys Pro Ala Lys Val Thr Pro Ala Pro Thr Leu Gln Arg Asp Phe
    130                 135                 140

Thr Ala Ala Phe Pro Arg Met Leu Thr Thr Arg Gly His Gly Pro Ala
145                 150                 155                 160

Glu Thr Gln Thr Leu Gly Ser Leu Pro Asp Ile Asn Leu Thr Gln Ile
                165                 170                 175

Ser Thr Leu Ala Asn Glu Leu Arg Asp Ser Arg Leu Ala Asn Asp Leu
            180                 185                 190

Arg Asp Ser Gly Ala Thr Ile Arg Ile Gly Ile Tyr Ile Gly Ala Xaa
        195                 200                 205

Ile Cys Ala Gly Leu Ala Leu Ala Leu Ile Phe Gly Ala Leu Ile Phe
    210                 215                 220

Lys Trp Tyr Ser His Ser Lys Glu Lys Ile Gln Asn Leu Ser Leu Ile
225                 230                 235                 240

Ser Leu Ala Asn Leu Pro Pro Ser Gly Leu Ala Asn Ala Val Ala Glu
                245                 250                 255

Gly Ile Arg Ser Glu Glu Asn Ile Tyr Thr Ile Glu Glu Asn Val Tyr
            260                 265                 270

Glu Val Glu Glu Pro Asn Glu Tyr Tyr Cys Tyr Val Ser Ser Arg Gln
        275                 280                 285

Gln Pro Ser Gln Pro Leu Gly Cys Arg Phe Ala Met Pro 
    290                 295                 300



<210> 2773
<211> 339
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (99)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (113)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2773
Met Thr Asp Cys Leu Val Ile Lys His Phe Leu Arg Lys Ile Ile Met
  1               5                  10                  15

Val His Pro Lys Val Arg Phe His Phe Ser Val Lys Val Asn Gly Ile
             20                  25                  30

Leu Ser Thr Glu Ile Phe Gly Val Glu Asn Glu Pro Thr Leu Asn Leu
         35                  40                  45

Gly Asn Gly Ile Ala Leu Leu Val Asp Ser Gln His Tyr Val Ser Arg
     50                  55                  60

Pro Asn Phe Gly Thr Ile Glu Ser His Cys Ser Arg Ile His Pro Val
 65                  70                  75                  80

Leu Gly His Pro Val Met Leu Phe Ile Pro Glu Asp Val Ala Gly Met
                 85                  90                  95

Asp Leu Xaa Gly Glu Leu Ile Leu Thr Xaa Ala Ala Ala Leu Cys Pro
            100                 105                 110

Xaa Pro Lys Val Ser Ser Asn Gln Leu Asn Arg Ile Ser Ser Val Ser
        115                 120                 125

Ile Phe Leu Tyr Gly Pro Leu Gly Leu Pro Leu Ile Leu Ser Thr Trp
    130                 135                 140

Glu Gln Pro Met Thr Thr Phe Phe Lys Asp Thr Ser Ser Leu Val Asp
145                 150                 155                 160

Trp Lys Lys Tyr His Leu Cys Met Ile Pro Asn Leu Asp Leu Asn Leu
                165                 170                 175

Asp Arg Asp Leu Val Leu Pro Asp Val Ser Tyr Gln Val Glu Ser Ser
            180                 185                 190

Glu Glu Asp Gln Ser Gln Thr Met Asp Pro Gln Gly Gln Thr Leu Leu
        195                 200                 205

Leu Phe Leu Phe Val Asp Phe His Ser Ala Phe Pro Val Gln Gln Met
    210                 215                 220

Glu Ile Trp Gly Val Tyr Thr Leu Leu Thr Thr His Leu Asn Ala Ile
225                 230                 235                 240

Leu Val Glu Ser His Ser Val Val Gln Gly Ser Ile Gln Phe Thr Val
                245                 250                 255

Asp Lys Val Leu Glu Gln His His Gln Ala Ala Lys Ala Gln Gln Lys
            260                 265                 270

Leu Gln Ala Ser Leu Ser Val Ala Val Asn Ser Ile Met Ser Ile Leu
        275                 280                 285

Thr Gly Ser Thr Arg Ser Ser Phe Arg Lys Met Cys Leu Gln Thr Leu
    290                 295                 300

Gln Ala Ala Asp Thr Gln Glu Phe Arg Thr Lys Leu His Lys Val Phe
305                 310                 315                 320

Arg Glu Ile Thr Gln His Gln Phe Leu His His Cys Ser Cys Glu Val
                325                 330                 335

Lys Gln Arg 




<210> 2774
<211> 465
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (126)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (158)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (161)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (169)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (427)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2774
Met Lys Arg Arg Thr Asp Pro Glu Cys Thr Ala Pro Ile Lys Lys Gln
  1               5                  10                  15

Lys Lys Arg Val Ala Glu Leu Ala Leu Ser Leu Ser Ser Thr Ser Asp
             20                  25                  30

Asp Glu Pro Pro Ser Ser Val Ser His Gly Ala Lys Ala Ser Thr Thr
         35                  40                  45

Ser Leu Ser Gly Ser Asp Ser Glu Thr Glu Gly Lys Gln His Ser Ser
     50                  55                  60

Asp Ser Phe Asp Asp Ala Phe Lys Ala Asp Ser Leu Val Glu Gly Thr
 65                  70                  75                  80

Ser Ser Arg Tyr Ser Met Tyr Asn Ser Val Ser Gln Lys Leu Met Ala
                 85                  90                  95

Lys Met Gly Phe Arg Glu Gly Glu Gly Leu Gly Lys Tyr Ser Gln Gly
            100                 105                 110

Arg Lys Asp Ile Val Glu Ala Ser Ser Gln Lys Gly Arg Xaa Gly Leu
        115                 120                 125

Gly Leu Thr Leu Arg Gly Phe Asp Gln Glu Leu Asn Val Asp Trp Arg
    130                 135                 140

Asp Glu Pro Glu Pro Ser Ala Cys Glu Gln Val Ser Trp Xaa Pro Glu
145                 150                 155                 160

Xaa Thr Thr Glu Ile Pro Asp Thr Xaa Glu Met Ser Asp Trp Met Val
                165                 170                 175

Val Gly Lys Arg Lys Met Ile Ile Glu Asp Glu Thr Glu Phe Cys Gly
            180                 185                 190

Glu Glu Leu Leu His Ser Val Leu Gln Cys Lys Ser Val Phe Asp Val
        195                 200                 205

Leu Asp Gly Glu Glu Met Arg Arg Ala Arg Thr Arg Ala Asn Pro Tyr
    210                 215                 220

Glu Met Ile Arg Gly Val Phe Phe Leu Asn Arg Ala Ala Met Lys Met
225                 230                 235                 240

Ala Asn Met Asp Phe Val Phe Asp Arg Met Phe Thr Asn Pro Arg Asp
                245                 250                 255

Ser Tyr Gly Lys Pro Leu Val Lys Asp Arg Glu Ala Glu Leu Leu Tyr
            260                 265                 270

Phe Ala Asp Val Cys Ala Gly Pro Gly Gly Phe Ser Glu Tyr Val Leu
        275                 280                 285

Trp Arg Lys Lys Trp His Ala Lys Gly Phe Gly Met Thr Leu Lys Gly
    290                 295                 300

Pro Asn Asp Phe Lys Leu Glu Asp Phe Tyr Ser Ala Ser Ser Glu Leu
305                 310                 315                 320

Phe Glu Pro Tyr Tyr Gly Glu Gly Gly Ile Asp Gly Asp Gly Asp Ile
                325                 330                 335

Thr Arg Pro Glu Asn Ile Ser Ala Phe Arg Asn Phe Val Leu Asp Asn
            340                 345                 350

Thr Asp Arg Lys Gly Val His Phe Leu Met Ala Asp Gly Gly Phe Ser
        355                 360                 365

Val Glu Gly Gln Glu Asn Leu Gln Glu Ile Leu Ser Lys Gln Leu Leu
    370                 375                 380

Leu Cys Gln Phe Leu Met Ala Leu Ser Ile Val Arg Thr Gly Gly His
385                 390                 395                 400

Phe Ile Cys Lys Thr Phe Asp Leu Phe Thr Pro Phe Ser Val Gly Leu
                405                 410                 415

Val Tyr Leu Leu Tyr Cys Cys Phe Glu Arg Xaa Cys Leu Phe Lys Pro
            420                 425                 430

Ile Thr Ser Arg Pro Ala Asn Ser Glu Arg Tyr Val Val Cys Lys Gly
        435                 440                 445

Leu Lys Val Gly Ile Asp Asp Val Arg Asp Tyr Leu Phe Ala Val Asn
    450                 455                 460

Ile 
465



<210> 2775
<211> 606
<212> PRT
<213> Homo sapiens

<400> 2775
Met Asp Ser Gln Arg Glu Leu Ala Glu Glu Leu Arg Leu Tyr Gln Ser
  1               5                  10                  15

Thr Leu Leu Gln Asp Gly Leu Lys Asp Leu Leu Asp Glu Lys Lys Phe
             20                  25                  30

Ile Asp Cys Thr Leu Lys Ala Gly Asp Lys Ser Leu Pro Cys His Arg
         35                  40                  45

Leu Ile Leu Ser Ala Cys Ser Pro Tyr Phe Arg Glu Tyr Phe Leu Ser
     50                  55                  60

Glu Ile Asp Glu Ala Lys Lys Lys Glu Val Val Leu Asp Asn Val Asp
 65                  70                  75                  80

Pro Ala Ile Leu Asp Leu Ile Ile Lys Tyr Leu Tyr Ser Ala Ser Ile
                 85                  90                  95

Asp Leu Asn Asp Gly Asn Val Gln Asp Ile Phe Ala Leu Ala Ser Arg
            100                 105                 110

Phe Gln Ile Pro Ser Val Phe Thr Val Cys Val Ser Tyr Leu Gln Lys
        115                 120                 125

Arg Leu Ala Pro Gly Asn Cys Leu Ala Ile Leu Arg Leu Gly Leu Leu
    130                 135                 140

Leu Asp Cys Pro Arg Leu Ala Ile Ser Ala Arg Glu Phe Val Ser Asp
145                 150                 155                 160

Arg Phe Val Gln Ile Cys Lys Glu Glu Asp Phe Met Gln Leu Ser Pro
                165                 170                 175

Gln Glu Leu Ile Ser Val Ile Ser Asn Asp Ser Leu Asn Val Glu Lys
            180                 185                 190

Glu Glu Ala Val Phe Glu Ala Val Met Lys Trp Val Arg Thr Asp Lys
        195                 200                 205

Glu Asn Arg Val Lys Asn Leu Ser Glu Val Phe Asp Cys Ile Arg Phe
    210                 215                 220

Arg Leu Met Thr Glu Lys Tyr Phe Lys Asp His Val Glu Lys Asp Asp
225                 230                 235                 240

Ile Ile Lys Ser Asn Pro Asp Leu Gln Lys Lys Ile Lys Val Leu Lys
                245                 250                 255

Asp Ala Phe Ala Gly Lys Leu Pro Glu Pro Ser Lys Asn Ala Ala Lys
            260                 265                 270

Thr Gly Ala Gly Glu Val Asn Gly Asp Val Gly Asp Glu Asp Leu Leu
        275                 280                 285

Pro Gly Tyr Leu Asn Asp Ile Pro Arg His Gly Met Phe Val Lys Asp
    290                 295                 300

Leu Ile Leu Leu Val Asn Asp Thr Ala Ala Val Ala Tyr Asp Pro Thr
305                 310                 315                 320

Glu Asn Glu Cys Tyr Leu Thr Ala Leu Ala Glu Gln Ile Pro Arg Asn
                325                 330                 335

His Ser Ser Ile Val Thr Gln Gln Asn Gln Ile Tyr Val Val Gly Gly
            340                 345                 350

Leu Tyr Val Asp Glu Glu Asn Lys Asp Gln Pro Leu Gln Ser Tyr Phe
        355                 360                 365

Phe Gln Leu Asp Ser Ile Ala Ser Glu Trp Val Gly Leu Pro Pro Leu
    370                 375                 380

Pro Ser Ala Arg Cys Leu Phe Gly Leu Gly Glu Val Asp Asp Lys Ile
385                 390                 395                 400

Tyr Val Val Ala Gly Lys Asp Leu Gln Thr Glu Ala Ser Leu Asp Ser
                405                 410                 415

Val Leu Cys Tyr Asp Pro Val Ala Ala Lys Trp Asn Glu Val Lys Lys
            420                 425                 430

Leu Pro Ile Lys Val Tyr Gly His Asn Val Ile Ser His Lys Gly Met
        435                 440                 445

Ile Tyr Cys Leu Gly Gly Lys Thr Asp Asp Lys Lys Cys Thr Asn Arg
    450                 455                 460

Val Phe Ile Phe Asn Pro Lys Lys Gly Asp Trp Lys Asp Leu Ala Pro
465                 470                 475                 480

Met Lys Ile Pro Arg Ser Met Phe Gly Val Ala Val His Lys Gly Lys
                485                 490                 495

Ile Val Ile Ala Gly Gly Val Thr Glu Asp Gly Leu Ser Ala Ser Val
            500                 505                 510

Glu Ala Phe Asp Leu Thr Thr Asn Lys Trp Asp Val Met Thr Glu Phe
        515                 520                 525

Pro Gln Glu Arg Ser Ser Ile Ser Leu Val Ser Leu Ala Gly Ser Leu
    530                 535                 540

Tyr Ala Ile Gly Gly Phe Ala Met Ile Gln Leu Glu Ser Lys Glu Phe
545                 550                 555                 560

Ala Pro Thr Glu Val Asn Asp Ile Trp Lys Tyr Glu Asp Asp Lys Lys
                565                 570                 575

Glu Trp Ala Gly Met Leu Lys Glu Ile Arg Tyr Ala Ser Gly Ala Ser
            580                 585                 590

Cys Leu Ala Thr Arg Leu Asn Leu Phe Lys Leu Ser Lys Leu 
        595                 600                 605



<210> 2776
<211> 386
<212> PRT
<213> Homo sapiens

<400> 2776
Met Glu Ala Glu Val Leu Gln Arg Leu His Asp Lys Leu Asp Pro Ser
  1               5                  10                  15

Pro Leu Arg Asp Thr Val Ala Ser Ala Leu Met Tyr His Arg Asn Glu
             20                  25                  30

Ser Leu Gln Pro Ser Leu Gln Ser Pro Gln Thr Glu Leu Arg Ser Asp
         35                  40                  45

Phe Gln Cys Val Val Gly Phe Gly Gly Ile His Ser Thr Pro Ser Thr
     50                  55                  60

Val Leu Ser Asp Gln Ala Lys Tyr Leu Asn Pro Leu Leu Gly Glu Trp
 65                  70                  75                  80

Lys His Phe Thr Ala Ser Leu Ala Pro Arg Met Ser Asn Gln Gly Ile
                 85                  90                  95

Ala Val Leu Asn Asn Phe Val Tyr Leu Ile Gly Gly Asp Asn Asn Val
            100                 105                 110

Gln Gly Phe Arg Ala Glu Ser Arg Cys Trp Arg Tyr Asp Pro Arg His
        115                 120                 125

Asn Arg Trp Phe Gln Ile Gln Ser Leu Gln Gln Glu His Ala Asp Leu
    130                 135                 140

Ser Val Cys Val Val Gly Arg Tyr Ile Tyr Ala Val Ala Gly Arg Asp
145                 150                 155                 160

Tyr His Asn Asp Leu Asn Ala Val Glu Arg Tyr Asp Pro Ala Thr Asn
                165                 170                 175

Ser Trp Ala Tyr Val Ala Pro Leu Lys Arg Glu Val Tyr Ala His Ala
            180                 185                 190

Gly Ala Thr Leu Glu Gly Lys Met Tyr Ile Thr Cys Gly Arg Arg Gly
        195                 200                 205

Glu Asp Tyr Leu Lys Glu Thr His Cys Tyr Asp Pro Gly Ser Asn Thr
    210                 215                 220

Trp His Thr Leu Ala Asp Gly Pro Val Arg Arg Ala Trp His Gly Met
225                 230                 235                 240

Ala Thr Leu Leu Asn Lys Leu Tyr Val Ile Gly Gly Ser Asn Asn Asp
                245                 250                 255

Ala Gly Tyr Arg Arg Asp Val His Gln Val Ala Cys Tyr Ser Cys Thr
            260                 265                 270

Ser Gly Gln Trp Ser Ser Val Cys Pro Leu Pro Ala Gly His Gly Glu
        275                 280                 285

Pro Gly Ile Ala Val Leu Asp Asn Arg Ile Tyr Val Leu Gly Gly Arg
    290                 295                 300

Ser His Asn Arg Gly Ser Arg Thr Gly Tyr Val His Ile Tyr Asp Val
305                 310                 315                 320

Glu Lys Asp Cys Trp Glu Glu Gly Pro Gln Leu Asp Asn Ser Ile Ser
                325                 330                 335

Gly Leu Ala Ala Cys Val Leu Thr Leu Pro Arg Ser Leu Leu Leu Glu
            340                 345                 350

Pro Pro Arg Gly Thr Pro Asp Arg Ser Gln Ala Asp Pro Asp Phe Ala
        355                 360                 365

Ser Glu Val Met Ser Val Ser Asp Trp Glu Glu Phe Asp Asn Ser Ser
    370                 375                 380

Glu Asp 
385



<210> 2777
<211> 239
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (54)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2777
Met His Leu Glu Gln Gln Met Leu Leu Lys Arg Leu Gly Asn Ala Tyr
  1               5                  10                  15

Ala Val Leu Ser Asn Pro Glu Lys Arg Lys Gln Tyr Asp Leu Thr Gly
             20                  25                  30

Asn Glu Glu Gln Ala Cys Asn His Gln Asn Asn Gly Arg Phe Asn Phe
         35                  40                  45

His Arg Gly Cys Glu Xaa Asp Ile Thr Pro Glu Asp Leu Phe Asn Ile
     50                  55                  60

Phe Phe Gly Gly Gly Phe Pro Ser Gly Ser Val His Ser Phe Ser Asn
 65                  70                  75                  80

Gly Arg Ala Gly Tyr Ser Gln Gln His Gln His Arg His Ser Gly His
                 85                  90                  95

Glu Arg Glu Glu Glu Arg Gly Asp Gly Gly Phe Ser Val Phe Ile Gln
            100                 105                 110

Leu Met Pro Ile Ile Val Leu Ile Leu Val Ser Leu Leu Ser Gln Leu
        115                 120                 125

Met Val Ser Asn Pro Pro Tyr Ser Leu Tyr Pro Arg Ser Gly Thr Gly
    130                 135                 140

Gln Thr Ile Lys Met Gln Thr Glu Asn Leu Gly Val Val Tyr Tyr Val
145                 150                 155                 160

Asn Lys Asp Phe Lys Asn Glu Tyr Lys Gly Met Leu Leu Gln Lys Val
                165                 170                 175

Glu Lys Ser Val Glu Glu Asp Tyr Val Thr Asn Ile Arg Asn Asn Cys
            180                 185                 190

Trp Lys Glu Arg Gln Gln Lys Thr Asp Met Gln Tyr Ala Ala Lys Val
        195                 200                 205

Tyr Arg Asp Asp Arg Leu Arg Arg Lys Ala Asp Ala Leu Ser Met Asp
    210                 215                 220

Asn Cys Lys Glu Leu Glu Arg Leu Thr Ser Leu Tyr Lys Gly Gly 
225                 230                 235



<210> 2778
<211> 351
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (187)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (192)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (195)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2778
Met Ile Ala Lys Glu Glu Leu Glu Ser Val Leu Glu Glu Glu Val Asp
  1               5                  10                  15

Asp Phe Pro Thr Phe Gly Asp Ser Gln Ser Asp Tyr Asp Thr Val Val
             20                  25                  30

His Pro Phe Tyr Ala Tyr Trp Gln Ser Phe Cys Thr Gln Lys Asn Phe
         35                  40                  45

Ala Trp Lys Glu Glu Tyr Asp Thr Arg Gln Ala Ser Asn Arg Trp Glu
     50                  55                  60

Lys Arg Ala Met Glu Lys Glu Asn Lys Lys Ile Arg Asp Lys Ala Arg
 65                  70                  75                  80

Lys Glu Lys Asn Glu Leu Val Arg Gln Leu Val Ala Phe Ile Arg Lys
                 85                  90                  95

Arg Asp Lys Arg Val Gln Ala His Arg Lys Leu Val Glu Glu Gln Asn
            100                 105                 110

Ala Glu Lys Ala Arg Lys Ala Glu Glu Met Arg Arg Gln Gln Lys Leu
        115                 120                 125

Lys Gln Ala Lys Leu Val Glu Gln Tyr Arg Glu Gln Ser Trp Met Thr
    130                 135                 140

Met Ala Asn Leu Glu Lys Glu Leu Gln Glu Met Glu Ala Arg Tyr Glu
145                 150                 155                 160

Lys Glu Phe Gly Asp Gly Ser Asp Glu Asn Glu Met Glu Glu His Glu
                165                 170                 175

Leu Lys Asp Glu Glu Asp Gly Lys Asp Ser Xaa Glu Ala Glu Asp Xaa
            180                 185                 190

Glu Leu Xaa Asp Asp Leu Tyr Cys Pro Ala Cys Asp Lys Ser Phe Lys
        195                 200                 205

Thr Glu Lys Ala Met Lys Asn His Glu Lys Ser Lys Lys His Arg Glu
    210                 215                 220

Met Val Ala Leu Leu Lys Gln Gln Leu Glu Glu Glu Glu Glu Asn Phe
225                 230                 235                 240

Ser Arg Pro Gln Ile Asp Glu Asn Pro Leu Asp Asp Asn Ser Glu Glu
                245                 250                 255

Glu Met Glu Asp Ala Pro Lys Gln Lys Leu Ser Lys Lys Gln Lys Lys
            260                 265                 270

Lys Lys Gln Lys Pro Ala Gln Asp Val Pro Gly Lys Asp Ser Tyr Leu
        275                 280                 285

Pro Ala Ala His Phe Gln Met Ala Trp Gly Lys Lys Cys Val Leu Gly
    290                 295                 300

Glu Arg Arg Asp Gly Glu Ser Glu His Lys Cys Ala Lys Met Leu Leu
305                 310                 315                 320

Glu Asn Arg Gln Val Arg Leu Gly Tyr Val Cys Gln Ala Ser Phe Phe
                325                 330                 335

Tyr Asn Ala Cys Leu Leu Leu Pro Leu Phe Val Thr Val Glu Glu 
            340                 345                 350



<210> 2779
<211> 163
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (145)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (146)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (148)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2779
Met Lys Ser Asp Leu Thr Arg Trp Arg Asn Pro Thr Asn Val Arg Asn
  1               5                  10                  15

Val Gly Lys Asn Ser Val Val Pro Val Pro Phe Thr Asp Met Lys Glu
             20                  25                  30

Leu Ile Val Glu Glu Asn Ser Thr Asn Val Lys Asn Val Pro Lys Ser
         35                  40                  45

Leu Asp Val Pro Arg Pro Phe Lys His Met Lys Glu Leu Thr Leu Glu
     50                  55                  60

Lys Asp Leu Met Asn Val Ile Asn Val Val Lys Pro Ser Ile Ile Pro
 65                  70                  75                  80

Val Val Phe Glu Asp Ile Lys Lys Thr His Ser Gly Glu Lys Pro Tyr
                 85                  90                  95

Glu Cys Thr Arg Cys Gly Lys Ala Phe Gly Trp Cys Ser Ser Leu Arg
            100                 105                 110

Arg His Glu Met Thr His Thr Gly Glu Lys Pro Phe Phe Cys Lys Gln
        115                 120                 125

Cys Gly Lys Val Phe Thr Phe Ser Xaa Tyr Leu Arg Leu Gln Glu Arg
    130                 135                 140

Xaa Xaa Trp Xaa Gly Val Pro Val Ala Phe Gly Arg Arg Gln Gly Gly
145                 150                 155                 160

Pro Pro Pro 




<210> 2780
<211> 546
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (534)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (537)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2780
Met Glu His Cys Leu Lys His Gly Leu Lys Val Lys Lys Ser Phe Ile
  1               5                  10                  15

Gly Gln Asn Lys Ser Phe Phe Gly Pro Leu Glu Leu Val Glu Lys Leu
             20                  25                  30

Cys Pro Glu Ala Ser Asp Ile Ala Thr Ser Val Arg Asn Leu Pro Glu
         35                  40                  45

Leu Lys Thr Ala Val Gly Arg Gly Arg Ala Trp Leu Tyr Leu Ala Leu
     50                  55                  60

Met Gln Lys Lys Leu Ala Asp Tyr Leu Lys Val Leu Ile Asp Asn Lys
 65                  70                  75                  80

His Leu Leu Ser Glu Phe Tyr Glu Pro Glu Ala Leu Met Met Glu Glu
                 85                  90                  95

Glu Gly Met Val Ile Val Gly Leu Leu Val Gly Leu Asn Val Leu Asp
            100                 105                 110

Ala Asn Leu Cys Leu Lys Gly Glu Asp Leu Asp Ser Gln Val Gly Val
        115                 120                 125

Ile Asp Phe Ser Leu Tyr Leu Lys Asp Val Gln Asp Leu Asp Gly Gly
    130                 135                 140

Lys Glu His Glu Arg Ile Thr Asp Val Leu Asp Gln Lys Asn Tyr Val
145                 150                 155                 160

Glu Glu Leu Asn Arg His Leu Ser Cys Thr Val Gly Asp Leu Gln Thr
                165                 170                 175

Lys Ile Asp Gly Leu Glu Lys Thr Asn Ser Lys Leu Gln Glu Glu Leu
            180                 185                 190

Ser Ala Ala Thr Asp Arg Ile Cys Ser Leu Gln Glu Glu Gln Gln Gln
        195                 200                 205

Leu Arg Glu Gln Asn Glu Leu Ile Arg Glu Arg Ser Glu Lys Ser Val
    210                 215                 220

Glu Ile Thr Lys Gln Asp Thr Lys Val Glu Leu Glu Thr Tyr Lys Gln
225                 230                 235                 240

Thr Arg Gln Gly Leu Asp Glu Met Tyr Ser Asp Val Trp Lys Gln Leu
                245                 250                 255

Lys Glu Glu Lys Lys Val Arg Leu Glu Leu Glu Lys Glu Leu Glu Leu
            260                 265                 270

Gln Ile Gly Met Lys Thr Glu Met Glu Ile Ala Met Lys Leu Leu Glu
        275                 280                 285

Lys Asp Thr His Glu Lys Gln Asp Thr Leu Val Ala Leu Arg Gln Gln
    290                 295                 300

Leu Glu Glu Val Lys Ala Ile Asn Leu Gln Met Phe His Lys Ala Gln
305                 310                 315                 320

Asn Ala Glu Ser Ser Leu Gln Gln Lys Asn Glu Ala Ile Thr Ser Phe
                325                 330                 335

Glu Gly Lys Thr Asn Gln Val Met Ser Ser Met Lys Gln Met Glu Glu
            340                 345                 350

Arg Leu Gln His Ser Glu Arg Ala Arg Gln Gly Ala Glu Glu Arg Ser
        355                 360                 365

His Lys Leu Gln Gln Glu Leu Gly Gly Arg Ile Gly Ala Leu Gln Leu
    370                 375                 380

Gln Leu Ser Gln Leu His Glu Gln Cys Ser Ser Leu Glu Lys Glu Leu
385                 390                 395                 400

Lys Ser Glu Lys Glu Gln Arg Gln Ala Leu Gln Arg Glu Leu Gln His
                405                 410                 415

Glu Lys Asp Thr Ser Ser Leu Leu Arg Met Glu Leu Gln Gln Val Glu
            420                 425                 430

Gly Leu Lys Lys Glu Leu Arg Glu Leu Gln Asp Glu Lys Ala Glu Leu
        435                 440                 445

Gln Lys Ile Cys Glu Glu Gln Glu Gln Ala Leu Gln Glu Met Gly Leu
    450                 455                 460

His Leu Ser Gln Ser Lys Leu Lys Met Glu Asp Ile Lys Glu Val Asn
465                 470                 475                 480

Gln Ala Leu Lys Gly His Ala Trp Leu Lys Asp Asp Glu Ala Thr His
                485                 490                 495

Cys Arg Gln Cys Glu Lys Glu Phe Ser Ile Ser Arg Arg Lys His His
            500                 505                 510

Cys Arg Asn Cys Gly His Ile Phe Cys Asn Thr Cys Ser Ser Asn Glu
        515                 520                 525

Leu Ala Leu Pro Ser Xaa Pro Lys Xaa Val Arg Val Cys Asp Thr Gly
    530                 535                 540

His Thr 
545



<210> 2781
<211> 209
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (79)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (170)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (197)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2781
Met Lys Val Ser Leu Gly Asn Gly Glu Met Gly Val Ser Ala His Leu
  1               5                  10                  15

Gln Pro Cys Lys Ala Gly Thr Thr Arg Phe Phe Thr Ser Asn Thr His
             20                  25                  30

Ser Ser Val Val Leu Gln Gly Phe Asp Gln Leu Arg Ile Glu Gly Leu
         35                  40                  45

Leu Cys Asp Val Thr Leu Val Pro Gly Asp Gly Asp Glu Ile Phe Pro
     50                  55                  60

Val His Arg Ala Met Met Ala Ser Ala Ser Asp Tyr Phe Lys Xaa Met
 65                  70                  75                  80

Phe Thr Gly Gly Met Lys Glu Gln Asp Leu Met Cys Ile Lys Leu His
                 85                  90                  95

Gly Val Asn Lys Val Gly Leu Lys Lys Ile Ile Asp Phe Ile Tyr Thr
            100                 105                 110

Ala Lys Leu Ser Leu Asn Met Asp Asn Leu Gln Asp Thr Leu Glu Ala
        115                 120                 125

Ala Ser Phe Leu Gln Ile Leu Pro Val Leu Asp Phe Cys Lys Val Phe
    130                 135                 140

Leu Ile Ser Gly Val Ser Leu Asp Asn Cys Val Glu Val Gly Arg Ile
145                 150                 155                 160

Ala Asn Thr Tyr Asn Leu Ile Glu Val Xaa Lys Tyr Val Asn Asn Phe
                165                 170                 175

Ile Leu Lys Asn Phe Pro Ala Leu Leu Ser Thr Gly Glu Phe Leu Lys
            180                 185                 190

Leu Pro Phe Glu Xaa Leu Ala Phe Val Leu Ser Ser Asn Ser Leu Ser
        195                 200                 205

Thr 




<210> 2782
<211> 156
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (134)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (143)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2782
Met Pro Gln Ala Ser Tyr Ile Met Thr Glu Leu Met Leu Val Lys Ser
  1               5                  10                  15

Pro Met Asn Val Lys Asn Val Gly Lys Leu Leu Val Met Leu His Ile
             20                  25                  30

Leu Leu Phe Met Arg Glu Phe Ile Pro Val Ile Asn Pro Met Asn Val
         35                  40                  45

Lys Asp Val Gly Arg His Phe Thr Val Pro His Ile Leu Leu Asp Met
     50                  55                  60

Lys Ala Phe Met Leu Met Glu Ile Pro Ile Cys Val Lys Ser Val Gly
 65                  70                  75                  80

Lys Leu Leu Ile Val Ala Met Asn Leu Val Tyr Ile Ile Xaa Phe Ile
                 85                  90                  95

Leu Val Arg Asn Pro Leu Asn Val Thr Asn Ala Glu Gly Pro Leu Gly
            100                 105                 110

Leu Asp Pro Ser Leu Glu Val His Gln Arg Asn Ser Tyr Leu Val Arg
        115                 120                 125

Gly Ile Val Gly Ile Xaa Gln Val Gly Lys Gly Lys Ala His Xaa Val
    130                 135                 140

His Gly Phe Tyr Pro His Trp Asn Ile Phe Gly Leu 
145                 150                 155



<210> 2783
<211> 324
<212> PRT
<213> Homo sapiens

<400> 2783
Met Ser Val Glu Asp Gly Gly Met Pro Gly Leu Gly Arg Pro Arg Gln
  1               5                  10                  15

Ala Arg Trp Thr Leu Met Leu Leu Leu Ser Thr Ala Met Tyr Gly Ala
             20                  25                  30

His Ala Pro Leu Leu Ala Leu Cys His Val Asp Gly Arg Val Pro Phe
         35                  40                  45

Arg Pro Ser Ser Ala Val Leu Leu Thr Glu Leu Thr Lys Leu Leu Leu
     50                  55                  60

Cys Ala Phe Ser Leu Leu Val Gly Trp Gln Ala Trp Pro Gln Gly Pro
 65                  70                  75                  80

Pro Pro Trp Arg Gln Ala Ala Pro Phe Ala Leu Ser Ala Leu Leu Tyr
                 85                  90                  95

Gly Ala Asn Asn Asn Leu Val Ile Tyr Leu Gln Arg Tyr Met Asp Pro
            100                 105                 110

Ser Thr Tyr Gln Val Leu Ser Asn Leu Lys Ile Gly Ser Thr Ala Val
        115                 120                 125

Leu Tyr Cys Leu Cys Leu Arg His Arg Leu Ser Val Arg Gln Gly Leu
    130                 135                 140

Ala Leu Leu Leu Leu Met Ala Ala Gly Ala Cys Tyr Ala Ala Gly Gly
145                 150                 155                 160

Leu Gln Val Pro Gly Asn Thr Leu Pro Ser Pro Pro Pro Ala Ala Ala
                165                 170                 175

Ala Ser Pro Met Pro Leu His Ile Thr Pro Leu Gly Leu Leu Leu Leu
            180                 185                 190

Ile Leu Tyr Cys Leu Ile Ser Gly Leu Ser Ser Val Tyr Thr Glu Leu
        195                 200                 205

Leu Met Lys Arg Gln Arg Leu Pro Leu Ala Leu Gln Asn Leu Phe Leu
    210                 215                 220

Tyr Thr Phe Gly Val Leu Leu Asn Leu Gly Leu His Ala Gly Gly Gly
225                 230                 235                 240

Ser Gly Pro Gly Leu Leu Glu Gly Phe Ser Gly Trp Ala Ala Leu Val
                245                 250                 255

Val Leu Ser Gln Ala Leu Asn Gly Leu Leu Met Ser Ala Val Met Lys
            260                 265                 270

His Gly Ser Ser Ile Thr Arg Leu Phe Val Val Ser Cys Ser Leu Val
        275                 280                 285

Val Asn Ala Val Leu Ser Ala Val Leu Leu Arg Leu Gln Leu Thr Ala
    290                 295                 300

Ala Phe Phe Leu Ala Thr Leu Leu Ile Gly Leu Ala Met Arg Leu Tyr
305                 310                 315                 320

Tyr Gly Ser Arg 




<210> 2784
<211> 365
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (304)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (323)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2784
Met Gly Arg Trp Ala Leu Asp Val Ala Phe Leu Trp Lys Ala Val Leu
  1               5                  10                  15

Thr Leu Gly Leu Val Leu Leu Tyr Tyr Cys Phe Ser Ile Gly Ile Thr
             20                  25                  30

Phe Tyr Asn Lys Trp Leu Thr Lys Ser Phe His Phe Pro Leu Phe Met
         35                  40                  45

Thr Met Leu His Leu Ala Val Ile Phe Leu Phe Ser Ala Leu Ser Arg
     50                  55                  60

Ala Leu Val Gln Cys Ser Ser His Arg Ala Arg Val Val Leu Ser Trp
 65                  70                  75                  80

Ala Asp Tyr Leu Arg Arg Val Ala Pro Thr Ala Leu Ala Thr Ala Leu
                 85                  90                  95

Asp Val Gly Leu Ser Asn Trp Ser Phe Leu Tyr Val Thr Val Ser Leu
            100                 105                 110

Tyr Thr Met Thr Lys Ser Ser Ala Val Leu Phe Ile Leu Ile Phe Ser
        115                 120                 125

Leu Ile Phe Lys Leu Glu Glu Leu Arg Ala Ala Leu Val Leu Val Val
    130                 135                 140

Leu Leu Ile Ala Gly Gly Leu Phe Met Phe Thr Tyr Lys Ser Thr Gln
145                 150                 155                 160

Phe Asn Val Glu Gly Phe Ala Leu Val Leu Gly Ala Ser Phe Ile Gly
                165                 170                 175

Gly Ile Arg Trp Thr Leu Thr Gln Met Leu Leu Gln Lys Ala Glu Leu
            180                 185                 190

Gly Leu Gln Asn Pro Ile Asp Thr Met Phe His Leu Gln Pro Leu Met
        195                 200                 205

Phe Leu Gly Leu Phe Pro Leu Phe Ala Val Phe Glu Gly Leu His Leu
    210                 215                 220

Ser Thr Ser Glu Lys Ile Phe Arg Phe Gln Asp Thr Gly Leu Leu Leu
225                 230                 235                 240

Arg Val Leu Gly Ser Leu Phe Leu Gly Gly Ile Leu Ala Phe Gly Leu
                245                 250                 255

Gly Phe Ser Glu Phe Leu Leu Val Ser Arg Thr Ser Ser Leu Thr Leu
            260                 265                 270

Ser Ile Ala Gly Ile Phe Lys Glu Val Cys Thr Leu Leu Leu Ala Ala
        275                 280                 285

His Leu Leu Gly Asp Gln Ile Ser Leu Leu Asn Trp Leu Gly Phe Xaa
    290                 295                 300

Leu Cys Leu Ser Gly Ile Ser Leu His Val Ala Leu Lys Ala Leu His
305                 310                 315                 320

Ser Arg Xaa Asp Gly Gly Pro Lys Ala Leu Lys Gly Leu Gly Ser Ser
                325                 330                 335

Pro Asp Leu Glu Leu Leu Leu Arg Ser Ser Gln Arg Glu Glu Gly Asp
            340                 345                 350

Asn Glu Glu Glu Glu Tyr Phe Val Ala Gln Gly Gln Gln 
        355                 360                 365



<210> 2785
<211> 393
<212> PRT
<213> Homo sapiens

<400> 2785
Met Ser Pro Ser Leu Asp Ser Arg Ser Phe Pro Val Trp Ser Trp Gly
  1               5                  10                  15

Leu Gly Asn Arg Gly Ala Gly Pro Pro Val Thr Glu Glu Glu Trp Ala
             20                  25                  30

Arg His Val Gly Pro Glu Gly Arg Leu Gln Gln Val Pro Glu Leu Lys
         35                  40                  45

Asn Arg Ile Phe Ser Gly Gly Leu Ser Pro Ser Leu Arg Arg Glu Ala
     50                  55                  60

Trp Lys Phe Leu Leu Gly Tyr Leu Ser Trp Glu Gly Thr Ala Glu Glu
 65                  70                  75                  80

His Lys Ala His Ile Arg Lys Lys Thr Asp Glu Tyr Phe Arg Met Lys
                 85                  90                  95

Leu Gln Trp Lys Ser Val Ser Pro Glu Gln Glu Arg Arg Asn Ser Leu
            100                 105                 110

Leu His Gly Tyr Arg Ser Leu Ile Glu Arg Asp Val Ser Arg Thr Asp
        115                 120                 125

Arg Thr Asn Lys Phe Tyr Glu Gly Pro Glu Asn Pro Gly Leu Gly Leu
    130                 135                 140

Leu Asn Asp Ile Leu Leu Thr Tyr Cys Met Tyr His Phe Asp Leu Gly
145                 150                 155                 160

Tyr Val Gln Gly Met Ser Asp Leu Leu Ser Pro Ile Leu Tyr Val Ile
                165                 170                 175

Gln Asn Glu Val Asp Ala Phe Trp Cys Phe Cys Gly Phe Met Glu Leu
            180                 185                 190

Val Gln Gly Asn Phe Glu Glu Ser Gln Glu Thr Met Lys Arg Gln Leu
        195                 200                 205

Gly Arg Leu Leu Leu Leu Leu Arg Val Leu Asp Pro Leu Leu Cys Asp
    210                 215                 220

Phe Leu Asp Ser Gln Asp Ser Gly Ser Leu Cys Phe Cys Phe Arg Trp
225                 230                 235                 240

Leu Leu Ile Trp Phe Lys Arg Glu Phe Pro Phe Pro Asp Val Leu Arg
                245                 250                 255

Leu Trp Glu Val Leu Trp Thr Gly Leu Pro Gly Pro Asn Leu His Leu
            260                 265                 270

Leu Val Ala Cys Ala Ile Leu Asp Met Glu Arg Asp Thr Leu Met Leu
        275                 280                 285

Ser Gly Phe Gly Ser Asn Glu Ile Leu Lys His Ile Asn Glu Leu Thr
    290                 295                 300

Met Lys Leu Ser Val Glu Asp Val Leu Thr Arg Ala Glu Ala Leu His
305                 310                 315                 320

Arg Gln Leu Thr Ala Cys Pro Glu Leu Pro His Asn Val Gln Glu Ile
                325                 330                 335

Leu Gly Leu Ala Pro Pro Ala Glu Pro His Ser Pro Ser Pro Thr Ala
            340                 345                 350

Ser Pro Leu Pro Leu Ser Pro Thr Arg Ala Pro Pro Thr Pro Pro Pro
        355                 360                 365

Ser Thr Asp Thr Ala Pro Gln Pro Asp Ser Ser Leu Glu Ile Leu Pro
    370                 375                 380

Glu Glu Glu Asp Glu Gly Ala Asp Ser 
385                 390



<210> 2786
<211> 367
<212> PRT
<213> Homo sapiens

<400> 2786
Met Pro Phe Ala Phe Phe Phe Leu Glu Ser Glu Gly Phe Ala Gly Leu
  1               5                  10                  15

Lys Lys Gly Ile Arg Ala Arg Ile Leu Glu Thr Leu Val Met Leu Leu
             20                  25                  30

Leu Leu Ala Leu Leu Ile Leu Gly Ile Val Trp Val Ala Ser Ala Leu
         35                  40                  45

Ile Asp Asn Asp Ala Ala Ser Met Glu Ser Leu Tyr Asp Leu Trp Glu
     50                  55                  60

Phe Tyr Leu Pro Tyr Leu Tyr Ser Cys Ile Ser Leu Met Gly Cys Leu
 65                  70                  75                  80

Leu Leu Leu Leu Cys Thr Pro Val Gly Leu Ser Arg Met Phe Thr Val
                 85                  90                  95

Met Gly Gln Leu Leu Val Lys Pro Thr Ile Leu Glu Asp Leu Asp Glu
            100                 105                 110

Gln Ile Tyr Ile Ile Thr Leu Glu Glu Glu Ala Leu Gln Arg Arg Leu
        115                 120                 125

Asn Gly Leu Ser Ser Ser Val Glu Tyr Asn Ile Met Glu Leu Glu Gln
    130                 135                 140

Glu Leu Glu Asn Val Lys Thr Leu Lys Thr Lys Leu Glu Arg Arg Lys
145                 150                 155                 160

Lys Ala Ser Ala Trp Glu Arg Asn Leu Val Tyr Pro Ala Val Met Val
                165                 170                 175

Leu Leu Leu Ile Glu Thr Ser Ile Ser Val Leu Leu Val Ala Cys Asn
            180                 185                 190

Ile Leu Cys Leu Leu Val Asp Glu Thr Ala Met Pro Lys Gly Thr Arg
        195                 200                 205

Gly Pro Gly Ile Gly Asn Ala Ser Leu Ser Thr Phe Gly Phe Val Gly
    210                 215                 220

Ala Ala Leu Glu Ile Ile Leu Ile Phe Tyr Leu Met Val Ser Ser Val
225                 230                 235                 240

Val Gly Phe Tyr Ser Leu Arg Phe Phe Gly Asn Phe Thr Pro Lys Lys
                245                 250                 255

Asp Asp Thr Thr Met Thr Lys Ile Ile Gly Asn Cys Val Ser Ile Leu
            260                 265                 270

Val Leu Ser Ser Ala Leu Pro Val Met Ser Arg Thr Leu Gly Ile Thr
        275                 280                 285

Arg Phe Asp Leu Leu Gly Asp Phe Gly Arg Phe Asn Trp Leu Gly Asn
    290                 295                 300

Phe Tyr Ile Val Leu Ser Tyr Asn Leu Leu Phe Ala Ile Val Thr Thr
305                 310                 315                 320

Leu Cys Leu Val Arg Lys Phe Thr Ser Ala Val Arg Glu Glu Leu Phe
                325                 330                 335

Lys Ala Leu Gly Leu His Lys Leu His Leu Pro Asn Thr Ser Arg Asp
            340                 345                 350

Ser Glu Thr Ala Lys Pro Ser Val Asn Gly His Gln Lys Ala Leu 
        355                 360                 365



<210> 2787
<211> 412
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (176)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (271)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (272)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (276)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (277)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (297)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (327)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2787
Met Ser Gly Asp Lys Leu Leu Ser Glu Leu Gly Tyr Lys Leu Gly Arg
  1               5                  10                  15

Thr Ile Gly Glu Gly Ser Tyr Ser Lys Val Lys Val Ala Thr Ser Lys
             20                  25                  30

Lys Tyr Lys Gly Thr Val Ala Ile Lys Val Val Asp Arg Arg Arg Ala
         35                  40                  45

Pro Pro Asp Phe Val Asn Lys Phe Leu Pro Arg Glu Leu Ser Ile Leu
     50                  55                  60

Arg Gly Val Arg His Pro His Ile Val His Val Phe Glu Phe Ile Glu
 65                  70                  75                  80

Val Cys Asn Gly Lys Leu Tyr Ile Val Met Glu Ala Ala Ala Thr Asp
                 85                  90                  95

Leu Leu Gln Ala Val Gln Arg Asn Gly Arg Ile Pro Gly Val Gln Ala
            100                 105                 110

Arg Asp Leu Phe Ala Gln Ile Ala Gly Ala Val Arg Tyr Leu His Asp
        115                 120                 125

His His Leu Val His Arg Asp Leu Lys Cys Glu Asn Val Leu Leu Ser
    130                 135                 140

Pro Asp Glu Arg Arg Val Lys Leu Thr Asp Phe Gly Phe Gly Arg Gln
145                 150                 155                 160

Ala His Gly Tyr Pro Asp Leu Ser Thr Thr Tyr Cys Gly Ser Ala Xaa
                165                 170                 175

Tyr Ala Ser Pro Glu Val Leu Leu Gly Ile Pro Tyr Asp Pro Lys Lys
            180                 185                 190

Tyr Asp Val Trp Ser Met Gly Val Val Leu Tyr Val Met Val Thr Gly
        195                 200                 205

Cys Met Pro Phe Asp Asp Ser Asp Ile Ala Gly Leu Pro Arg Arg Gln
    210                 215                 220

Lys Arg Gly Val Leu Tyr Pro Glu Gly Leu Glu Leu Ser Glu Arg Cys
225                 230                 235                 240

Lys Ala Leu Ile Ala Glu Leu Leu Gln Phe Ser Pro Ser Ala Gly Pro
                245                 250                 255

Ser Ala Gly Gln Val Ala Arg Asn Cys Trp Leu Arg Ala Gly Xaa Xaa
            260                 265                 270

Arg Leu Glu Xaa Xaa Trp Phe Gln Pro Phe Leu Gln Pro Arg Ala Leu
        275                 280                 285

Gly Gln Gly Gly Ala Arg Ala Arg Xaa Ala Leu Arg Gly Asn Met Arg
    290                 295                 300

Ser Cys Arg Val Leu Leu His Met Arg Phe Phe Pro Ser Ala Ser Leu
305                 310                 315                 320

Pro Phe Phe Pro Arg Gly Xaa Pro Gln Leu Pro Leu Phe Gly Ile His
                325                 330                 335

Val Pro Arg Asp Pro Gly Ser Trp Arg Arg Met Arg Ile Arg Asp Ser
            340                 345                 350

Leu Arg Pro Gly Pro Glu Arg Ala Arg Pro Glu Gly Thr Glu Ala Leu
        355                 360                 365

Arg Leu Arg Gly Thr Leu Ser Leu Cys Ala Glu Gly Val Pro Ser Gln
    370                 375                 380

Pro Ala Val Gly Ala Arg Phe Pro Val Gly Thr Cys Asn Lys Leu Ala
385                 390                 395                 400

Val Pro Arg Lys Lys Lys Lys Lys Lys Lys Thr Arg 
                405                 410



<210> 2788
<211> 146
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (94)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2788
Met Glu Gln Arg His Val Leu Leu Lys Gln Lys Glu Leu Gly Gly Glu
  1               5                  10                  15

Glu Pro Glu Pro Ser Leu Arg Glu Gly Pro Gly Gly Leu Val Met Glu
             20                  25                  30

Gly His Leu Phe Lys Arg Ala Ser Asn Ala Phe Lys Thr Trp Ser Arg
         35                  40                  45

Arg Trp Phe Thr Ile Gln Ser Asn Gln Leu Val Tyr Gln Lys Lys Tyr
     50                  55                  60

Lys Asp Pro Val Thr Val Val Val Asp Asp Leu Arg Leu Cys Thr Val
 65                  70                  75                  80

Asn Ser Ala Leu Thr Gln Lys Gly Gly Ser Ala Leu Arg Xaa Cys Pro
                 85                  90                  95

Pro Ala Ser Pro Ala Ser Ser Arg Leu Thr Gln Ser Ala Ser Cys Ser
            100                 105                 110

Cys Gly Ser Val Leu Cys Arg Ala Ala Leu Leu Leu Pro Ser Val Arg
        115                 120                 125

Leu Ala Leu Met Thr Ala Pro Gly Val Gln Ala Arg Ala Gln Asp Thr
    130                 135                 140

Trp Pro 
145



<210> 2789
<211> 174
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (51)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (76)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2789
Met Arg Cys Lys Ile Ala Gln Gly Ala Ala Asn Gly Ile Asn Phe Leu
  1               5                  10                  15

His Glu Asn His His Ile His Arg Asp Ile Lys Ser Ala Asn Ile Leu
             20                  25                  30

Leu Asp Glu Ala Phe Thr Ala Lys Ile Ser Asp Phe Gly Leu Ala Arg
         35                  40                  45

Ala Ser Xaa Lys Phe Ala Gln Thr Val Met Thr Ser Arg Ile Val Gly
     50                  55                  60

Thr Thr Ala Tyr Met Ala Pro Glu Ala Leu Arg Xaa Glu Ile Thr Pro
 65                  70                  75                  80

Lys Ser Asp Ile Tyr Ser Phe Gly Val Val Leu Leu Glu Ile Ile Thr
                 85                  90                  95

Gly Leu Pro Ala Val Asp Glu His Arg Glu Pro Gln Leu Leu Leu Asp
            100                 105                 110

Ile Lys Glu Glu Ile Glu Asp Glu Glu Lys Thr Ile Glu Asp Tyr Ile
        115                 120                 125

Asp Lys Lys Met Asn Asp Ala Asp Ser Thr Ser Val Glu Ala Met Tyr
    130                 135                 140

Ser Val Ala Ser Gln Cys Leu His Glu Lys Lys Asn Lys Arg Pro Asp
145                 150                 155                 160

Ile Lys Lys Val Gln Gln Leu Leu Gln Glu Met Thr Ala Ser 
                165                 170



<210> 2790
<211> 365
<212> PRT
<213> Homo sapiens

<400> 2790
Met Asn Ile Met Asp Phe Asn Val Lys Lys Leu Ala Ala Asp Ala Gly
  1               5                  10                  15

Thr Phe Leu Ser Arg Ala Val Gln Phe Thr Glu Glu Lys Leu Gly Gln
             20                  25                  30

Ala Glu Lys Thr Glu Leu Asp Ala His Leu Glu Asn Leu Leu Ser Lys
         35                  40                  45

Ala Glu Cys Thr Lys Ile Trp Thr Glu Lys Ile Met Lys Gln Thr Glu
     50                  55                  60

Val Leu Leu Gln Pro Asn Pro Asn Ala Arg Ile Glu Glu Phe Val Tyr
 65                  70                  75                  80

Glu Lys Leu Asp Arg Lys Ala Pro Ser Arg Ile Asn Asn Pro Glu Leu
                 85                  90                  95

Leu Gly Gln Tyr Met Ile Asp Ala Gly Thr Glu Phe Gly Pro Gly Thr
            100                 105                 110

Ala Tyr Gly Asn Ala Leu Ile Lys Cys Gly Glu Thr Gln Lys Arg Ile
        115                 120                 125

Gly Thr Ala Asp Arg Glu Leu Ile Gln Thr Ser Ala Leu Asn Phe Leu
    130                 135                 140

Thr Pro Leu Arg Asn Phe Ile Glu Gly Asp Tyr Lys Thr Ile Ala Lys
145                 150                 155                 160

Glu Arg Lys Leu Leu Gln Asn Lys Arg Leu Asp Leu Asp Ala Ala Lys
                165                 170                 175

Thr Arg Leu Lys Lys Ala Lys Ala Ala Glu Thr Arg Asn Ser Ser Glu
            180                 185                 190

Gln Glu Leu Arg Ile Thr Gln Ser Glu Phe Asp Arg Gln Ala Glu Ile
        195                 200                 205

Thr Arg Leu Leu Leu Glu Gly Ile Ser Ser Thr His Ala His His Leu
    210                 215                 220

Arg Cys Leu Asn Asp Phe Val Glu Ala Gln Met Thr Tyr Tyr Ala Gln
225                 230                 235                 240

Cys Tyr Gln Tyr Met Leu Asp Leu Gln Lys Gln Leu Gly Ser Phe Pro
                245                 250                 255

Ser Asn Tyr Leu Ser Asn Asn Asn Gln Thr Ser Val Thr Pro Val Pro
            260                 265                 270

Ser Val Leu Pro Asn Ala Ile Gly Ser Ser Ala Met Ala Ser Thr Ser
        275                 280                 285

Gly Leu Val Ile Thr Ser Pro Ser Asn Leu Ser Asp Leu Lys Glu Cys
    290                 295                 300

Ser Gly Ser Arg Lys Ala Arg Val Leu Tyr Asp Tyr Asp Ala Ala Asn
305                 310                 315                 320

Ser Thr Glu Leu Ser Leu Leu Ala Asp Glu Val Ile Thr Val Phe Ser
                325                 330                 335

Val Val Gly Met Asp Ser Asp Trp Leu Met Gly Glu Arg Gly Asn Gln
            340                 345                 350

Lys Gly Lys Val Pro Ile Thr Tyr Leu Glu Leu Leu Asn 
        355                 360                 365



<210> 2791
<211> 372
<212> PRT
<213> Homo sapiens

<400> 2791
Met Ala Thr Ser Pro Gln Lys Ser Pro Ser Val Pro Lys Ser Pro Thr
  1               5                  10                  15

Pro Lys Ser Pro Pro Ser Arg Lys Lys Asp Asp Ser Phe Leu Gly Lys
             20                  25                  30

Leu Gly Gly Thr Leu Ala Arg Arg Lys Lys Ala Lys Glu Val Ser Glu
         35                  40                  45

Leu Gln Glu Glu Gly Met Asn Ala Ile Asn Leu Pro Leu Ser Pro Ile
     50                  55                  60

Pro Phe Glu Leu Asp Pro Glu Asp Thr Met Leu Glu Glu Asn Glu Val
 65                  70                  75                  80

Arg Thr Met Val Asp Pro Asn Ser Arg Ser Thr Pro Lys Leu Gln Glu
                 85                  90                  95

Leu Met Lys Val Leu Ile Asp Trp Ile Asn Asp Val Leu Val Gly Glu
            100                 105                 110

Arg Ile Ile Val Lys Asp Leu Ala Glu Asp Leu Tyr Asp Gly Gln Val
        115                 120                 125

Leu Gln Lys Leu Phe Glu Lys Leu Glu Ser Glu Lys Leu Asn Val Ala
    130                 135                 140

Glu Val Thr Gln Ser Glu Ile Ala Gln Lys Gln Lys Leu Gln Thr Val
145                 150                 155                 160

Leu Glu Lys Ile Asn Glu Thr Leu Lys Leu Pro Pro Arg Ser Ile Lys
                165                 170                 175

Trp Asn Val Asp Ser Val His Ala Lys Ser Leu Val Ala Ile Leu His
            180                 185                 190

Leu Leu Val Ala Leu Ser Gln Tyr Phe Arg Ala Pro Ile Arg Leu Pro
        195                 200                 205

Asp His Val Ser Ile Gln Val Val Val Val Gln Lys Arg Glu Gly Ile
    210                 215                 220

Leu Gln Ser Arg Gln Ile Gln Glu Glu Ile Thr Gly Asn Thr Glu Ala
225                 230                 235                 240

Leu Ser Gly Arg His Glu Arg Asp Ala Phe Asp Thr Leu Phe Asp His
                245                 250                 255

Ala Pro Asp Lys Leu Asn Val Val Lys Lys Thr Leu Ile Thr Phe Val
            260                 265                 270

Asn Lys His Leu Asn Lys Leu Asn Leu Glu Val Thr Glu Leu Glu Thr
        275                 280                 285

Gln Phe Ala Asp Gly Val Tyr Leu Val Leu Leu Met Gly Leu Leu Glu
    290                 295                 300

Gly Tyr Phe Val Pro Leu His Ser Phe Phe Leu Thr Pro Asp Ser Phe
305                 310                 315                 320

Glu Gln Lys Val Leu Asn Val Ser Phe Ala Phe Glu Leu Met Gln Asp
                325                 330                 335

Gly Gly Leu Glu Lys Pro Lys Pro Arg Pro Glu Asp Ile Val Asn Cys
            340                 345                 350

Asp Leu Lys Ser Thr Leu Arg Val Leu Tyr Asn Leu Phe Thr Lys Tyr
        355                 360                 365

Arg Asn Val Glu 
    370



<210> 2792
<211> 338
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (137)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2792
Met Thr Leu Arg Asp Asp Gln Pro Ala Lys Leu Glu Lys Glu Pro Lys
  1               5                  10                  15

Thr Arg Pro Glu Glu Asn Lys Pro Glu Arg Pro Ser Gly Arg Lys Pro
             20                  25                  30

Arg Pro Met Gly Ile Ile Ala Ala Asn Val Glu Lys His Tyr Glu Thr
         35                  40                  45

Gly Arg Val Ile Gly Asp Gly Asn Phe Ala Val Val Lys Glu Cys Arg
     50                  55                  60

His Arg Glu Thr Arg Gln Ala Tyr Ala Met Lys Ile Ile Asp Lys Ser
 65                  70                  75                  80

Arg Leu Lys Gly Lys Glu Asp Met Val Asp Ser Glu Ile Leu Ile Ile
                 85                  90                  95

Gln Ser Leu Ser His Pro Asn Ile Val Lys Leu His Glu Val Tyr Glu
            100                 105                 110

Thr Asp Met Glu Ile Tyr Leu Ile Leu Glu Tyr Val Gln Gly Gly Asp
        115                 120                 125

Leu Phe Asp Ala Ile Ile Glu Ser Xaa Lys Phe Pro Glu Pro Asp Ala
    130                 135                 140

Ala Leu Met Ile Met Asp Leu Cys Lys Ala Leu Val His Met His Asp
145                 150                 155                 160

Lys Ser Ile Val His Arg Asp Leu Lys Pro Glu Asn Leu Leu Val Gln
                165                 170                 175

Arg Asn Glu Asp Lys Ser Thr Thr Leu Lys Leu Ala Asp Phe Gly Leu
            180                 185                 190

Ala Lys His Val Val Arg Pro Ile Phe Thr Val Cys Gly Thr Pro Thr
        195                 200                 205

Tyr Val Ala Pro Glu Ile Leu Ser Glu Lys Gly Tyr Gly Leu Glu Val
    210                 215                 220

Asp Met Trp Ala Ala Gly Val Ile Leu Tyr Ile Leu Leu Cys Gly Phe
225                 230                 235                 240

Pro Pro Phe Arg Ser Pro Glu Arg Asp Gln Asp Glu Leu Phe Asn Ile
                245                 250                 255

Ile Gln Leu Gly His Phe Glu Phe Leu Pro Pro Tyr Trp Asp Asn Ile
            260                 265                 270

Ser Asp Ala Ala Lys Asp Leu Val Ser Arg Leu Leu Val Val Asp Pro
        275                 280                 285

Lys Lys Arg Tyr Thr Ala His Gln Val Leu Gln His Pro Trp Ile Glu
    290                 295                 300

Thr Ala Gly Lys Thr Asn Thr Val Lys Arg Gln Lys Gln Val Ser Pro
305                 310                 315                 320

Ser Ser Glu Gly His Phe Arg Ser Gln His Lys Arg Val Val Glu Gln
                325                 330                 335

Val Ser 




<210> 2793
<211> 363
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (52)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (159)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (339)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (346)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (359)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2793
Met Ala Pro Ala Pro Ile Trp Leu Cys Trp Ala Ala Gly Gln Val Val
  1               5                  10                  15

Arg Arg Leu Cys Ala Ser Thr Glu Asp Cys Glu Val Asp Pro Ser Lys
             20                  25                  30

Cys Pro Ala Ser Glu Leu Pro Glu His Gln Ala Arg Leu Arg Asn Ser
         35                  40                  45

Cys Glu Glu Xaa Pro Arg Leu Thr Ile His Cys Leu Phe Cys Thr Ser
     50                  55                  60

Trp Phe Pro Ala Glu Leu Gly Ile Val Phe Ser Ser Trp Arg Glu Ala
 65                  70                  75                  80

Cys Lys Glu Arg Gly Ser Glu Val Leu Gly Pro Arg Leu Val Cys Ala
                 85                  90                  95

Ser Leu Phe Leu Arg Leu Leu Cys Pro Ala Ile Leu Ala Pro Ser Leu
            100                 105                 110

Phe Gly Leu Ala Pro Asp His Pro Ala Pro Gly Pro Ala Arg Thr Leu
        115                 120                 125

Thr Leu Ile Ala Lys Val Ile Gln Asn Leu Ala Asn Arg Ala Pro Phe
    130                 135                 140

Gly Glu Lys Glu Ala Tyr Met Gly Phe Met Asn Ser Phe Leu Xaa Glu
145                 150                 155                 160

His Gly Pro Ala Met Gln Cys Phe Leu Asp Gln Val Ala Met Val Asp
                165                 170                 175

Val Asp Ala Ala Pro Ser Gly Tyr Gln Gly Ser Gly Asp Leu Ala Leu
            180                 185                 190

Gln Leu Ala Val Leu His Ala Gln Leu Cys Thr Ile Phe Ala Glu Leu
        195                 200                 205

Asp Gln Thr Thr Arg Asp Thr Leu Glu Pro Leu Pro Thr Ile Leu Arg
    210                 215                 220

Ala Ile Glu Glu Gly Gln Pro Val Leu Val Ser Val Pro Met Arg Leu
225                 230                 235                 240

Pro Leu Pro Pro Ala Gln Val His Ser Ser Leu Ser Ala Gly Arg Ser
                245                 250                 255

Pro Ala Ser Trp Pro Pro Gly Thr Ser Pro Ser Thr Pro Leu Ser Ser
            260                 265                 270

Pro Arg Ala Ser Leu Cys Ala Val Ser Pro Leu Arg Glu Leu Gly Pro
        275                 280                 285

Ala Thr Ala Gly Arg Arg Ala Ala Pro Ala Ala Ala Pro Ala Gly Ala
    290                 295                 300

Ala His Ala Glu Cys Pro Gly Pro Ala Ser Cys Pro Pro Pro Pro Ile
305                 310                 315                 320

Cys Gly Ala Leu Ala Ala Thr Gln Arg Leu Pro Glu His Gly Thr Ser
                325                 330                 335

Ala Pro Xaa Pro Ala Leu Asp Pro Gly Xaa Arg Phe Ala Ala Ser Glu
            340                 345                 350

Ala Ser Val Thr Leu Ala Xaa Pro Asn Trp Asn 
        355                 360



<210> 2794
<211> 108
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (19)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (47)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (81)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (85)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2794
Met Asn Gly Pro Ala Gly Leu Ala Gly Arg Leu Gln Glu His Ala Glu
  1               5                  10                  15

Pro Lys Xaa Gln Ala Xaa Gln Glu Gly Pro Leu Gln Lys Pro Ser Asp
             20                  25                  30

Gly Gly Ala Glu Pro Glu Pro Trp Ala Asp Ala Val Pro Ser Xaa Ala
         35                  40                  45

Gly Pro Arg Ala Glu Gly Gly Leu Ala Glu Glu Ala Glu Glu His His
     50                  55                  60

Glu Glu Leu Ala Ala Ala Leu Val Leu Cys Cys Val Gly Ile Ser Phe
 65                  70                  75                  80

Xaa Thr Thr Arg Xaa Lys Met Arg Ser Ser Pro Arg Arg Ile Ser Glu
                 85                  90                  95

Gly Ser Ser Ala Ile Arg Ser His Arg Arg Leu Ile 
            100                 105



<210> 2795
<211> 198
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (97)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (107)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (198)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2795
Met Phe Phe Leu Phe Ser Asp Met Leu Leu Tyr Thr Ser Lys Gly Val
  1               5                  10                  15

Ala Gly Thr Ser His Phe Arg Ile Arg Gly Leu Leu Pro Leu Gln Gly
             20                  25                  30

Met Leu Val Glu Glu Ser Asp Asn Glu Trp Ser Val Pro His Cys Phe
         35                  40                  45

Thr Ile Tyr Ala Ala Gln Lys Thr Ile Val Val Ala Ala Ser Thr Arg
     50                  55                  60

Leu Glu Lys Glu Lys Trp Met Leu Asp Leu Asn Ser Ala Ile Gln Ala
 65                  70                  75                  80

Ala Lys Ser Gly Gly Asp Thr Ala Pro Ala Leu Pro Gly Arg Thr Val
                 85                  90                  95

Xaa Leu Val Pro Pro Asp Pro Pro Thr Arg Xaa Leu Trp Ser Arg Ser
            100                 105                 110

Gln Lys Met Met Leu Gly Val Ser Ala Ala Pro Trp Arg Gly Met Ala
        115                 120                 125

Ala Pro Gly Gln His His Asn Ala Arg Val Leu Gly Thr Gly Thr Pro
    130                 135                 140

Ala Cys Pro Gly Gln Asp His Ser Ala Ala Val Glu Asn Gln Ala Phe
145                 150                 155                 160

Arg Ile Ser Ala Lys Lys Val Gln Lys Gln Val Met Gly Trp Gln Lys
                165                 170                 175

Leu Trp Val Val Phe Thr Asn Phe Cys Phe Val Leu Leu Thr Lys Leu
            180                 185                 190

Ile Arg Asp Asp Tyr Xaa 
        195



<210> 2796
<211> 107
<212> PRT
<213> Homo sapiens

<400> 2796
Met Gly His Ile Lys Leu Thr Asp Phe Gly Leu Ser Lys Val Gly Leu
  1               5                  10                  15

Met Ser Met Thr Thr Asn Leu Tyr Glu Gly His Ile Glu Lys Asp Ala
             20                  25                  30

Arg Glu Phe Leu Asp Lys Gln Val Cys Gly Thr Pro Glu Tyr Ile Ala
         35                  40                  45

Pro Glu Val Ile Leu Arg Gln Gly Tyr Gly Lys Pro Val Asp Trp Trp
     50                  55                  60

Ala Met Gly Ile Ile Leu Tyr Glu Phe Leu Val Gly Cys Val Pro Phe
 65                  70                  75                  80

Phe Gly Asp Thr Pro Glu Gly Tyr Leu Asp Lys Ser Ser Val Met Arg
                 85                  90                  95

Ser Thr Gly Leu Arg Arg Met Arg His Pro Thr 
            100                 105



<210> 2797
<211> 262
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (22)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (106)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (110)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2797
Met Glu Glu Arg Leu Ala Glu Phe Ile Ser Ser Asn Thr Pro Asp Ser
  1               5                  10                  15

Val Leu Pro Leu Ala Xaa Gly Ala Leu Ser Phe Ile His His Gln Val
             20                  25                  30

Ile Glu Met Ala Arg Asp Cys Leu Asp Lys Ser Arg Ser Gly Leu Ile
         35                  40                  45

Thr Ser Gln Tyr Phe Tyr Glu Leu Gln Glu Asn Leu Glu Lys Leu Leu
     50                  55                  60

Gln Asp Ala His Glu Arg Ser Glu Ser Ser Glu Val Ala Phe Val Met
 65                  70                  75                  80

Gln Leu Val Lys Lys Leu Met Ile Ile Ile Ala Arg Pro Ala Arg Leu
                 85                  90                  95

Leu Glu Cys Leu Glu Phe Asp Pro Glu Xaa Phe Tyr His Xaa Leu Glu
            100                 105                 110

Ala Ala Glu Gly His Ala Lys Glu Gly Gln Gly Ile Lys Cys Asp Ile
        115                 120                 125

Pro Arg Tyr Ile Val Ser Gln Leu Gly Leu Thr Arg Asp Pro Leu Glu
    130                 135                 140

Glu Met Ala Gln Leu Ser Ser Cys Asp Ser Pro Asp Thr Pro Glu Thr
145                 150                 155                 160

Asp Asp Ser Ile Glu Gly His Gly Ala Ser Leu Pro Ser Lys Lys Thr
                165                 170                 175

Pro Ser Glu Glu Asp Phe Glu Thr Ile Lys Leu Ile Ser Asn Gly Ala
            180                 185                 190

Tyr Gly Ala Val Phe Leu Val Arg His Lys Ser Thr Arg Gln Arg Phe
        195                 200                 205

Ala Met Lys Lys Ile Asn Lys Gln Asn Leu Ile Leu Arg Asn Gln Ile
    210                 215                 220

Gln Gln Ala Phe Val Glu Arg Asp Ile Leu Thr Phe Ala Glu Asn Pro
225                 230                 235                 240

Phe Val Val Ser Met Phe Cys Ser Phe Asp Thr Lys Arg Gln Leu Cys
                245                 250                 255

Met Val Met Glu Leu Arg 
            260



<210> 2798
<211> 171
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (84)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (101)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2798
Met Glu Asp Glu Asp Glu Gln Gly Trp Cys Lys Glu Arg Leu Asp Asn
  1               5                  10                  15

Gly Gln Ile Met Trp Arg Arg Ser Ser Asp Glu Ser Gly Thr Gly Gln
             20                  25                  30

Arg Gly Asp Gly Gly Gly Gly Pro Arg Ser Leu Ser Gln Pro Arg Gly
         35                  40                  45

His Pro Leu Leu Phe Leu Gln Glu Met Met Val Pro Leu Leu Leu Ala
     50                  55                  60

Ser Trp Cys Ser Trp Lys Ala Asp Glu Leu Val Ile Ser Pro Gly Thr
 65                  70                  75                  80

Arg His Leu Xaa Glu Cys Ser Trp Arg Asp Leu Ser Ala Gly Arg Arg
                 85                  90                  95

Arg Thr Thr Glu Xaa Ala Ala Pro Pro Arg Pro Leu Ser Cys Trp Pro
            100                 105                 110

Ile Ile Asp Leu Tyr Val Leu Asp Phe Val Ser Pro Phe Arg Val Asn
        115                 120                 125

Gly Gly Leu His Leu Ile Leu Val Pro Leu Ile Thr Leu Leu Arg Asn
    130                 135                 140

Gly Val His Ser Thr Trp Gln Pro Lys Trp Thr Arg Leu Thr Phe Pro
145                 150                 155                 160

Ile Trp Asn Glu Gly Ile Trp Arg Phe Phe Phe 
                165                 170



<210> 2799
<211> 121
<212> PRT
<213> Homo sapiens

<400> 2799
Met Ser Arg Ala Gly Ala Arg Asp Ala Trp Thr Thr Gly Lys Leu Ala
  1               5                  10                  15

Tyr Thr Arg Gln Ile Met Trp Arg Arg Ser Ser Asp Glu Ser Gly Thr
             20                  25                  30

Gly Gln Arg Gly Asp Gly Gly Gly Gly Pro Arg Ser Leu Ser Gln Pro
         35                  40                  45

Arg Gly His Pro Leu Leu Phe Leu Gln Glu Met Met Val Pro Leu Leu
     50                  55                  60

Leu Ala Ser Trp Cys Ser Trp Lys Ala Asp Glu Leu Val Ile Ser Pro
 65                  70                  75                  80

Gly Thr Arg His Leu Ser Glu Cys Ser Trp Arg Asp Leu Ser Ala Gly
                 85                  90                  95

Arg Arg Arg Thr Thr Glu Ile Ala Ala Pro Pro Arg Pro Leu Cys Leu
            100                 105                 110

Leu Ala Tyr His Arg Ser Leu Cys Ser 
        115                 120



<210> 2800
<211> 198
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (172)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2800
Met Glu Ala Ser Val Ile Leu Pro Ile Leu Lys Lys Lys Leu Ala Phe
  1               5                  10                  15

Leu Ser Gly Gly Lys Asp Arg Arg Ser Gly Leu Ile Leu Thr Ile Pro
             20                  25                  30

Leu Cys Leu Glu Gln Thr Asn Met Asp Glu Leu Ser Val Thr Leu Asp
         35                  40                  45

Tyr Leu Leu Ser Ile Pro Ser Glu Lys Cys Lys Ala Arg Gly Phe Thr
     50                  55                  60

Val Ile Val Asp Gly Arg Lys Ser Gln Trp Asn Val Val Lys Thr Val
 65                  70                  75                  80

Val Val Met Leu Gln Asn Val Val Pro Ala Glu Val Ser Leu Val Cys
                 85                  90                  95

Val Val Lys Pro Asp Glu Phe Trp Asp Lys Lys Val Thr His Phe Cys
            100                 105                 110

Phe Trp Lys Glu Lys Asp Arg Leu Gly Phe Glu Val Ile Leu Val Ser
        115                 120                 125

Ala Asn Lys Leu Thr Arg Tyr Ile Glu Pro Cys Gln Leu Thr Glu Asp
    130                 135                 140

Phe Gly Gly Ser Leu Thr Tyr Asp His Met Asp Trp Leu Asn Lys Arg
145                 150                 155                 160

Leu Val Phe Glu Lys Phe Thr Lys Glu Ser Thr Xaa Leu Leu Asp Glu
                165                 170                 175

Leu Ala Leu Ile Asn Asn Gly Lys Cys Ile Lys Glu Ile Ser Lys Arg
            180                 185                 190

Lys Lys Gly Leu Trp Ile 
        195



<210> 2801
<211> 179
<212> PRT
<213> Homo sapiens

<400> 2801
Met Val Ala Leu Asn Phe Gln Thr Pro Gly Leu Pro Met Asp Leu Gln
  1               5                  10                  15

Asn Gly Lys Phe Leu Asp Asn Gly Gly Ser Gly Tyr Ile Leu Lys Pro
             20                  25                  30

His Phe Leu Arg Glu Ser Lys Ser Tyr Phe Asn Pro Ser Asn Ile Lys
         35                  40                  45

Glu Gly Met Pro Ile Thr Leu Thr Ile Arg Leu Ile Ser Gly Ile Gln
     50                  55                  60

Leu Pro Leu Thr His Ser Ser Ser Asn Lys Gly Asp Ser Leu Val Ile
 65                  70                  75                  80

Ile Glu Val Phe Gly Val Pro Asn Asp Gln Met Lys Gln Gln Thr Arg
                 85                  90                  95

Val Ile Lys Lys Asn Ala Phe Ser Pro Arg Trp Asn Glu Thr Phe Thr
            100                 105                 110

Phe Ile Ile His Val Pro Glu Leu Ala Leu Ile Arg Phe Val Val Glu
        115                 120                 125

Gly Gln Gly Leu Ile Ala Gly Asn Glu Phe Leu Gly Gln Tyr Thr Leu
    130                 135                 140

Pro Leu Leu Cys Met Asn Lys Gly Tyr Arg Arg Ile Pro Leu Phe Ser
145                 150                 155                 160

Arg Met Gly Glu Ser Leu Glu Pro Ala Ser Leu Phe Val Tyr Val Trp
                165                 170                 175

Tyr Val Arg 




<210> 2802
<211> 306
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (11)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (27)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (295)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (297)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (300)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (304)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2802
Met His Thr Leu His Thr Arg Ala Ala Ser Xaa Tyr Ser Ser Trp Ala
  1               5                  10                  15

Glu Glu Gln Arg His Leu Glu Thr Gly Ala Xaa Lys Ile Glu Ala Asp
             20                  25                  30

Ser Arg Thr Leu Trp Ala His Cys Trp Cys Pro Leu Leu Gln Gly Ile
         35                  40                  45

Ala Cys Leu Cys Cys Asp Ala Arg Arg Gln Val Arg Met Gln Ala Leu
     50                  55                  60

Thr Tyr Leu Gln Arg Ala Leu Leu Val His Asp Leu Gln Lys Leu Asp
 65                  70                  75                  80

Ala Leu Glu Trp Glu Ser Cys Phe Asn Lys Val Leu Phe Pro Leu Leu
                 85                  90                  95

Thr Lys Leu Leu Glu Asn Ile Ser Pro Ala Asp Val Gly Gly Met Glu
            100                 105                 110

Glu Thr Arg Met Arg Ala Ser Thr Leu Leu Ser Lys Val Phe Leu Gln
        115                 120                 125

His Leu Ser Pro Leu Leu Ser Leu Ser Thr Phe Ala Ala Leu Trp Leu
    130                 135                 140

Thr Ile Leu Asp Phe Met Asp Lys Tyr Met His Ala Gly Ser Ser Asp
145                 150                 155                 160

Leu Leu Ser Glu Ala Ile Pro Glu Ser Leu Lys Asn Met Leu Leu Val
                165                 170                 175

Met Asp Thr Ala Glu Ile Phe His Ser Ala Asp Ala Arg Gly Gly Gly
            180                 185                 190

Pro Ser Ala Leu Trp Glu Ile Thr Trp Glu Arg Ile Asp Cys Phe Leu
        195                 200                 205

Pro His Leu Arg Asp Glu Leu Phe Lys Gln Thr Val Ile Gln Asp Pro
    210                 215                 220

Met Pro Met Glu Pro Gln Gly Gln Lys Pro Leu Ala Ser Ala His Leu
225                 230                 235                 240

Thr Ser Ala Ala Gly Asp Thr Arg Thr Pro Gly His Pro Pro Pro Pro
                245                 250                 255

Glu Ile Pro Ser Glu Leu Gly Ala Cys Asp Phe Glu Lys Pro Glu Ser
            260                 265                 270

Pro Arg Ala Ala Ser Ser Ser Ser Pro Gly Ser Pro Val Ala Ser Ser
        275                 280                 285

Pro Ser Arg Leu Ser Pro Xaa Pro Xaa Gly Leu Xaa Pro Trp Leu Xaa
    290                 295                 300

Pro His 
305



<210> 2803
<211> 355
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (313)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (314)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2803
Met Arg Glu Asp Trp Ile Glu Glu Glu Cys His Arg Val Glu Ala Gln
  1               5                  10                  15

Leu Ala Leu Lys Glu Ala Arg Lys Glu Ile Lys Gln Leu Lys Gln Val
             20                  25                  30

Ile Glu Thr Met Arg Ser Ser Leu Ala Asp Lys Asp Lys Gly Ile Gln
         35                  40                  45

Lys Tyr Phe Val Asp Ile Asn Ile Gln Asn Lys Lys Leu Glu Ser Leu
     50                  55                  60

Leu Gln Ser Met Glu Met Ala His Ser Gly Ser Leu Arg Asp Glu Leu
 65                  70                  75                  80

Cys Leu Asp Phe Pro Cys Asp Ser Pro Glu Lys Ser Leu Thr Leu Asn
                 85                  90                  95

Pro Pro Leu Asp Thr Met Ala Asp Gly Leu Ser Leu Glu Glu Gln Val
            100                 105                 110

Thr Gly Glu Gly Ala Asp Arg Glu Leu Leu Val Gly Asp Ser Ile Ala
        115                 120                 125

Asn Ser Thr Asp Leu Phe Asp Glu Ile Val Thr Ala Thr Thr Thr Glu
    130                 135                 140

Ser Gly Asp Leu Glu Leu Val His Ser Thr Pro Gly Ala Asn Val Leu
145                 150                 155                 160

Glu Leu Leu Pro Ile Val Met Gly Gln Glu Glu Gly Ser Val Val Val
                165                 170                 175

Glu Arg Ala Val Gln Thr Asp Val Val Pro Tyr Ser Pro Ala Ile Ser
            180                 185                 190

Glu Leu Ile Gln Ser Val Leu Gln Lys Leu Gln Asp Pro Cys Pro Ser
        195                 200                 205

Ser Leu Ala Ser Pro Asp Glu Ser Glu Pro Asp Ser Met Glu Ser Phe
    210                 215                 220

Pro Glu Ser Leu Ser Ala Leu Val Val Asp Leu Thr Pro Arg Asn Pro
225                 230                 235                 240

Asn Ser Ala Ile Leu Leu Ser Pro Val Glu Thr Pro Tyr Ala Asn Val
                245                 250                 255

Asp Ala Glu Val His Ala Asn Arg Leu Met Arg Glu Leu Asp Phe Ala
            260                 265                 270

Ala Cys Val Glu Glu Arg Leu Asp Gly Val Ile Pro Leu Ala Arg Gly
        275                 280                 285

Gly Val Val Arg Gln Tyr Trp Ser Ser Ser Phe Leu Val Asp Leu Leu
    290                 295                 300

Ala Val Ala Ala Pro Val Val Pro Xaa Xaa Leu Trp Ala Phe Ser Thr
305                 310                 315                 320

Gln Arg Gly Gly Thr Asp Pro Val Tyr Asn Ile Gly Ala Leu Leu Arg
                325                 330                 335

Gly Cys Cys Val Val Ala Leu His Ser Leu Arg Arg Thr Ala Phe Arg
            340                 345                 350

Ile Lys Thr 
        355



<210> 2804
<211> 141
<212> PRT
<213> Homo sapiens

<400> 2804
Met Glu Gln Lys His Arg Cys Lys Phe Ala Met Lys Glu Ile Val Gln
  1               5                  10                  15

Phe Met Ala Ser Gly Arg Leu Gly Pro Val Gly Val Pro Val Leu Cys
             20                  25                  30

His Val Glu Glu Val Pro Asp Arg Glu Gln Gly Ala Ala Pro Thr Leu
         35                  40                  45

Cys Pro Ser Met Glu Glu Gly Asn Ala Lys Gly Val Met Ser Arg Val
     50                  55                  60

Ile Phe Ala Thr Val Thr Leu Ala Gln Pro Met Val Thr Gly Val Leu
 65                  70                  75                  80

Gly Val Ala Gly Glu His Ala Ala Gly Arg Val Thr Glu Gly Arg Cys
                 85                  90                  95

Gly Gly Thr Ala His Val Ile Thr Leu Leu Pro Pro Met Gly Glu Glu
            100                 105                 110

Leu Val Gly Asp Gln Thr Pro Arg Ser Arg Gly Ala Thr Leu Thr Cys
        115                 120                 125

Val Leu Trp Met Glu Val Gly Glu Ala Gly Ile Val Glu 
    130                 135                 140



<210> 2805
<211> 329
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (53)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (62)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (306)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2805
Met Pro Gly Lys His Gln His Phe Gln Glu Pro Glu Val Gly Cys Cys
  1               5                  10                  15

Gly Lys Tyr Phe Leu Phe Gly Phe Asn Ile Val Phe Trp Val Leu Gly
             20                  25                  30

Ala Leu Phe Leu Ala Ile Gly Leu Trp Ala Trp Gly Glu Lys Gly Val
         35                  40                  45

Leu Ser Asn Ile Xaa Ala Leu Thr Asp Leu Gly Gly Leu Xaa Pro Val
     50                  55                  60

Trp Leu Phe Val Val Val Gly Gly Val Met Ser Val Leu Gly Phe Ala
 65                  70                  75                  80

Gly Cys Ile Gly Ala Leu Arg Glu Asn Thr Phe Leu Leu Lys Phe Phe
                 85                  90                  95

Ser Val Phe Leu Gly Leu Ile Phe Phe Leu Glu Leu Ala Thr Gly Ile
            100                 105                 110

Leu Ala Phe Val Phe Lys Asp Trp Ile Arg Asp Gln Leu Asn Leu Phe
        115                 120                 125

Ile Asn Asn Asn Val Lys Ala Tyr Arg Asp Asp Ile Asp Leu Gln Asn
    130                 135                 140

Leu Ile Asp Phe Ala Gln Glu Tyr Trp Ser Cys Cys Gly Ala Arg Gly
145                 150                 155                 160

Pro Asn Asp Trp Asn Leu Asn Ile Tyr Phe Asn Cys Thr Asp Leu Asn
                165                 170                 175

Pro Ser Arg Glu Arg Cys Gly Val Pro Phe Ser Cys Cys Val Arg Asp
            180                 185                 190

Pro Ala Glu Asp Val Leu Asn Thr Gln Cys Gly Tyr Asp Val Arg Leu
        195                 200                 205

Lys Leu Glu Leu Glu Gln Gln Gly Phe Ile His Thr Lys Gly Cys Val
    210                 215                 220

Gly Gln Phe Glu Lys Trp Leu Gln Asp Asn Leu Ile Val Val Ala Gly
225                 230                 235                 240

Val Phe Met Gly Ile Ala Leu Leu Gln Ile Phe Gly Ile Cys Leu Ala
                245                 250                 255

Gln Asn Leu Val Ser Asp Ile Lys Ala Val Lys Ala Asn Trp Ser Lys
            260                 265                 270

Trp Asn Asp Asp Phe Glu Asn His Trp Leu Thr Pro Thr Ile Ser Glu
        275                 280                 285

Val Leu Ser Thr Ala Gly Pro Gln Gln Asn Ser Leu Thr Gly Ala Pro
    290                 295                 300

Gly Xaa Ala Pro Pro Ser Arg His Val Phe Phe Gly Leu Gly Gly Leu
305                 310                 315                 320

Tyr Pro Glu Pro Thr Phe Lys Asn Trp 
                325



<210> 2806
<211> 511
<212> PRT
<213> Homo sapiens

<400> 2806
Met Ile Ser Asp Asn Ser Ala Glu Asn Ile Ala Leu Val Thr Ser Met
  1               5                  10                  15

Tyr Asp Gly Leu Leu Gln Ala Gly Ala Arg Leu Cys Pro Thr Val Gln
             20                  25                  30

Leu Glu Asp Ile Arg Asn Leu Gln Asp Leu Thr Pro Leu Lys Leu Ala
         35                  40                  45

Ala Lys Glu Gly Lys Ile Glu Ile Phe Arg His Ile Leu Gln Arg Glu
     50                  55                  60

Phe Ser Gly Leu Ser His Leu Ser Arg Lys Phe Thr Glu Trp Cys Tyr
 65                  70                  75                  80

Gly Pro Val Arg Val Ser Leu Tyr Asp Leu Ala Ser Val Asp Ser Cys
                 85                  90                  95

Glu Glu Asn Ser Val Leu Glu Ile Ile Ala Phe His Cys Lys Ser Pro
            100                 105                 110

His Arg His Arg Met Val Val Leu Glu Pro Leu Asn Lys Leu Leu Gln
        115                 120                 125

Ala Lys Trp Asp Leu Leu Ile Pro Lys Phe Phe Leu Asn Phe Leu Cys
    130                 135                 140

Asn Leu Ile Tyr Met Phe Ile Phe Thr Ala Val Ala Tyr His Gln Pro
145                 150                 155                 160

Thr Leu Lys Lys Gln Ala Ala Pro His Leu Lys Ala Glu Val Gly Asn
                165                 170                 175

Ser Met Leu Leu Thr Gly His Ile Leu Ile Leu Leu Gly Gly Ile Tyr
            180                 185                 190

Leu Leu Val Gly Gln Leu Trp Tyr Phe Trp Arg Arg His Val Phe Ile
        195                 200                 205

Trp Ile Ser Phe Ile Asp Ser Tyr Phe Glu Ile Leu Phe Leu Phe Gln
    210                 215                 220

Ala Leu Leu Thr Val Val Ser Gln Val Leu Cys Phe Leu Ala Ile Glu
225                 230                 235                 240

Trp Tyr Leu Pro Leu Leu Val Ser Ala Leu Val Leu Gly Trp Leu Asn
                245                 250                 255

Leu Leu Tyr Tyr Thr Arg Gly Phe Gln His Thr Gly Ile Tyr Ser Val
            260                 265                 270

Met Ile Gln Lys Val Ile Leu Arg Asp Leu Leu Arg Phe Leu Leu Ile
        275                 280                 285

Tyr Leu Val Phe Leu Phe Gly Phe Ala Val Ala Leu Val Ser Leu Ser
    290                 295                 300

Gln Glu Ala Trp Arg Pro Glu Ala Pro Thr Gly Pro Asn Ala Thr Glu
305                 310                 315                 320

Ser Val Gln Pro Met Glu Gly Gln Glu Asp Glu Gly Asn Gly Ala Gln
                325                 330                 335

Tyr Arg Gly Ile Leu Glu Ala Ser Leu Glu Leu Phe Lys Phe Thr Ile
            340                 345                 350

Gly Met Gly Glu Leu Ala Phe Gln Glu Gln Leu His Phe Arg Gly Met
        355                 360                 365

Val Leu Leu Leu Leu Leu Ala Tyr Val Leu Leu Thr Tyr Ile Leu Leu
    370                 375                 380

Leu Asn Met Leu Ile Ala Leu Met Ser Glu Thr Val Asn Ser Val Ala
385                 390                 395                 400

Thr Asp Ser Trp Ser Ile Trp Lys Leu Gln Lys Ala Ile Ser Val Leu
                405                 410                 415

Glu Met Glu Asn Gly Tyr Trp Trp Cys Arg Lys Lys Gln Arg Ala Gly
            420                 425                 430

Val Met Leu Thr Val Gly Thr Lys Pro Asp Gly Ser Pro Asp Glu Arg
        435                 440                 445

Trp Cys Phe Arg Val Glu Glu Val Asn Trp Ala Ser Trp Glu Gln Thr
    450                 455                 460

Leu Pro Thr Leu Cys Glu Asp Pro Ser Gly Ala Gly Val Pro Arg Thr
465                 470                 475                 480

Leu Glu Asn Pro Val Leu Ala Ser Pro Pro Lys Glu Asp Glu Asp Gly
                485                 490                 495

Ala Ser Glu Glu Asn Tyr Val Pro Val Gln Leu Leu Gln Ser Asn 
            500                 505                 510



<210> 2807
<211> 190
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (179)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (189)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2807
Met Ala Ala Ser Ser Ile Ser Ser Pro Trp Gly Lys His Val Phe Lys
  1               5                  10                  15

Ala Ile Leu Met Val Leu Val Ala Leu Ile Leu Leu His Ser Ala Leu
             20                  25                  30

Ala Gln Ser Arg Arg Asp Phe Ala Pro Pro Gly Gln Gln Lys Arg Glu
         35                  40                  45

Ala Pro Val Asp Val Leu Thr Gln Ile Gly Arg Ser Val Arg Gly Thr
     50                  55                  60

Leu Asp Ala Trp Ile Gly Pro Glu Thr Met His Leu Val Ser Glu Ser
 65                  70                  75                  80

Ser Ser Gln Val Leu Trp Ala Ile Ser Ser Ala Ile Ser Val Ala Phe
                 85                  90                  95

Phe Ala Leu Ser Gly Ile Ala Ala Gln Leu Leu Asn Ala Leu Gly Leu
            100                 105                 110

Ala Gly Asp Tyr Leu Ala Gln Gly Leu Lys Leu Ser Pro Gly Gln Val
        115                 120                 125

Gln Thr Phe Leu Leu Trp Gly Ala Gly Ala Leu Val Val Tyr Trp Leu
    130                 135                 140

Leu Ser Leu Leu Leu Gly Leu Val Leu Ala Leu Leu Gly Arg Ile Leu
145                 150                 155                 160

Trp Gly Leu Lys Leu Val Ile Phe Leu Ala Gly Phe Val Ala Leu Met
                165                 170                 175

Arg Ser Xaa Pro Asp Pro Ser Thr Arg Pro Cys Tyr Xaa Trp 
            180                 185                 190



<210> 2808
<211> 144
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (78)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2808
Met Val Gly Leu His Thr Phe Gly Gln Cys Thr Leu Thr Ile Gly Ile
  1               5                  10                  15

Ser Asp Ile Asn Asp Asn Cys Pro Leu Phe Thr Asp Ser Gln Ile Asn
             20                  25                  30

Val Thr Val Tyr Gly Asn Ala Thr Val Gly Thr Pro Ile Ala Ala Val
         35                  40                  45

Gln Ala Val Asp Lys Asp Leu Gly Thr Asn Ala Gln Ile Thr Tyr Ser
     50                  55                  60

Tyr Ser Gln Lys Val Pro Gln Ala Ser Lys Asp Leu Phe Xaa Leu Asp
 65                  70                  75                  80

Glu Asn Thr Gly Val Ile Lys Leu Phe Ser Lys Ile Gly Gly Ser Val
                 85                  90                  95

Leu Glu Ser His Lys Leu Thr Ile Leu Ala Asn Gly Pro Gly Cys Ile
            100                 105                 110

Pro Ala Val Ile Thr Ala Leu Val Ser Ile Ile Lys Val Ile Phe Arg
        115                 120                 125

Pro Pro Glu Ile Val Pro Arg Tyr Ile Ala Asn Glu Ile Asp Gly Val
    130                 135                 140






<210> 2809
<211> 465
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (333)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (406)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2809
Met Leu Ala Leu Gly Asn Asn His Phe Ile Gly Phe Val Asn Asp Ser
  1               5                  10                  15

Val Thr Lys Ser Ile Val Ala Leu Arg Leu Thr Leu Val Val Lys Val
             20                  25                  30

Ser Thr Cys Val Pro Gly Glu Ser His Ala Asn Asp Leu Glu Cys Ser
         35                  40                  45

Gly Lys Gly Lys Cys Thr Thr Lys Pro Ser Glu Ala Thr Phe Ser Cys
     50                  55                  60

Thr Cys Glu Glu Gln Tyr Val Gly Thr Phe Cys Glu Glu Tyr Asp Ala
 65                  70                  75                  80

Cys Gln Arg Lys Pro Cys Gln Asn Asn Ala Ser Cys Ile Asp Ala Asn
                 85                  90                  95

Glu Lys Gln Asp Gly Ser Asn Phe Thr Cys Val Cys Leu Pro Gly Tyr
            100                 105                 110

Thr Gly Glu Leu Cys Gln Ser Lys Ile Asp Tyr Cys Ile Leu Asp Pro
        115                 120                 125

Cys Arg Asn Gly Ala Thr Cys Ile Ser Ser Leu Ser Gly Phe Thr Cys
    130                 135                 140

Gln Cys Pro Glu Gly Tyr Phe Gly Ser Ala Cys Glu Glu Lys Val Asp
145                 150                 155                 160

Pro Cys Ala Ser Ser Pro Cys Gln Asn Asn Gly Thr Cys Tyr Val Asp
                165                 170                 175

Gly Val His Phe Thr Cys Asn Cys Ser Pro Gly Phe Thr Gly Pro Thr
            180                 185                 190

Cys Ala Gln Leu Ile Asp Phe Cys Ala Leu Ser Pro Cys Ala His Gly
        195                 200                 205

Thr Cys Arg Ser Val Gly Thr Ser Tyr Lys Cys Leu Cys Asp Pro Gly
    210                 215                 220

Tyr His Gly Leu Tyr Cys Glu Glu Glu Tyr Asn Glu Cys Leu Ser Ala
225                 230                 235                 240

Pro Cys Leu Asn Ala Ala Thr Cys Arg Asp Leu Val Asn Gly Tyr Glu
                245                 250                 255

Cys Val Cys Leu Ala Glu Tyr Lys Gly Thr His Cys Glu Leu Tyr Lys
            260                 265                 270

Asp Pro Cys Ala Asn Val Ser Cys Leu Asn Gly Ala Thr Cys Asp Ser
        275                 280                 285

Asp Gly Leu Asn Gly Thr Cys Ile Cys Ala Pro Gly Phe Thr Gly Glu
    290                 295                 300

Glu Cys Asp Ile Asp Ile Asn Glu Cys Asp Ser Asn Pro Cys His His
305                 310                 315                 320

Gly Gly Ser Cys Leu Asp Gln Pro Asn Gly Tyr Asn Xaa His Cys Pro
                325                 330                 335

His Gly Trp Val Gly Ala Asn Cys Glu Ile His Leu Gln Trp Lys Ser
            340                 345                 350

Gly His Met Ala Glu Ser Leu Thr Asn Met Pro Arg His Ser Leu Tyr
        355                 360                 365

Ile Ile Ile Gly Ala Leu Cys Val Ala Phe Ile Leu Met Leu Ile Ile
    370                 375                 380

Leu Ile Val Gly Ile Cys Arg Ile Ser Arg Ile Glu Tyr Gln Gly Ser
385                 390                 395                 400

Ser Arg Pro Ala Tyr Xaa Glu Phe Tyr Asn Cys Arg Ser Ile Asp Ser
                405                 410                 415

Glu Phe Ser Asn Ala Ile Ala Ser Ile Arg His Ala Arg Phe Gly Lys
            420                 425                 430

Lys Ser Arg Pro Ala Met Tyr Asp Val Ser Pro Ile Ala Tyr Glu Asp
        435                 440                 445

Tyr Ser Pro Asp Asp Lys Pro Leu Val Thr Leu Ile Lys Thr Lys Asp
    450                 455                 460

Leu 
465



<210> 2810
<211> 197
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (121)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2810
Met Cys Leu Gly Gly Thr Ser Pro Phe Leu Pro Gln Val Glu Ala His
  1               5                  10                  15

Asn Thr Val Thr Ser Gly Thr Ala Thr Thr Val Ile Glu Ile Gln Val
             20                  25                  30

Ser Glu Gln Glu Pro Pro Ser Thr Ala Gln Thr Pro Glu Ala Gly Thr
         35                  40                  45

Ser Gln Pro Met Pro Pro Gly Met Gly Thr Ser Thr Ser His Gln Pro
     50                  55                  60

Thr Thr Pro Gly Gly Gly Thr Ala Gln Thr Pro Glu Pro Gly Thr Ser
 65                  70                  75                  80

Gln Pro Met Pro Leu Ser Lys Ser Thr Pro Ser Ser Gly Gly Gly Pro
                 85                  90                  95

Ser Glu Asp Lys Arg Phe Ser Val Val Asp Met Ala Ala Leu Gly Gly
            100                 105                 110

Val Leu Gly Ala Leu Leu Leu Leu Xaa Leu Leu Gly Leu Ala Val Leu
        115                 120                 125

Val His Lys His Tyr Gly Pro Arg Ser Ser Ala Ala Leu Ala Lys Leu
    130                 135                 140

Arg Ser Pro Ser Pro Lys Ala Leu Thr Thr Arg Arg Ser Ser Leu Thr
145                 150                 155                 160

Thr Arg Xaa Thr Gly Arg Pro Ser Pro Ala Pro Arg Thr Thr Pro Ser
                165                 170                 175

Pro Arg Arg His Arg Cys Pro Gln Ser Pro His Pro Pro Ala Leu Pro
            180                 185                 190

Pro Gln Ala Val Pro 
        195



<210> 2811
<211> 184
<212> PRT
<213> Homo sapiens

<400> 2811
Met Gly Asn Gly Met Asn Lys Ile Leu Pro Gly Leu Tyr Ile Gly Asn
  1               5                  10                  15

Phe Lys Asp Ala Arg Asp Ala Glu Gln Leu Ser Lys Asn Lys Val Thr
             20                  25                  30

His Ile Leu Ser Val His Asp Ser Ala Arg Pro Met Leu Glu Gly Val
         35                  40                  45

Lys Tyr Leu Cys Ile Pro Ala Ala Asp Ser Pro Ser Gln Asn Leu Thr
     50                  55                  60

Arg His Phe Lys Glu Ser Ile Lys Phe Ile His Glu Cys Arg Leu Arg
 65                  70                  75                  80

Gly Glu Ser Cys Leu Val His Cys Leu Ala Gly Val Ser Arg Ser Val
                 85                  90                  95

Thr Leu Val Ile Ala Tyr Ile Met Thr Val Thr Asp Phe Gly Trp Glu
            100                 105                 110

Asp Ala Leu His Thr Val Arg Ala Gly Arg Ser Cys Ala Asn Pro Asn
        115                 120                 125

Val Gly Phe Gln Arg Gln Leu Gln Glu Phe Glu Lys His Glu Val His
    130                 135                 140

Gln Tyr Arg Gln Trp Leu Lys Glu Glu Tyr Gly Glu Ser Pro Leu Gln
145                 150                 155                 160

Asp Ala Glu Glu Ala Lys Asn Ile Leu Ala Ala Pro Gly Ile Leu Lys
                165                 170                 175

Phe Trp Ala Phe Leu Arg Arg Leu 
            180



<210> 2812
<211> 123
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (38)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (46)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (82)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (123)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2812
Met Arg Pro His Gly Ala Trp Leu Gly Arg Ala Gly Arg Val Arg Val
  1               5                  10                  15

Leu Glu Asp Gly Thr Leu Glu Ile Arg Ser Val Gln Leu Arg Asp Arg
             20                  25                  30

Gly Ala Tyr Val Cys Xaa Val Ser Asn Val Ala Gly Asn Xaa Ser Leu
         35                  40                  45

Arg Thr Trp Leu Glu Val Ile Gln Val Glu Pro Pro Asn Gly Thr Leu
     50                  55                  60

Ser Asp Pro Asn Ile Thr Val Pro Gly Ile Pro Gly Pro Phe Phe Leu
 65                  70                  75                  80

Asp Xaa Arg Gly Val Ala Met Val Leu Glu Val Gly Phe Leu Pro Phe
                 85                  90                  95

Leu Thr Ser Val Thr Leu Cys Phe Gly Leu Ile Ala Leu Gly Ser Lys
            100                 105                 110

Gly Lys Gly Arg Val Lys His His Met Thr Xaa 
        115                 120



<210> 2813
<211> 185
<212> PRT
<213> Homo sapiens

<400> 2813
Met Ser Pro Arg Ser Cys Leu Arg Ser Leu Arg Leu Leu Val Phe Ala
  1               5                  10                  15

Val Phe Ser Ala Ala Ala Ser Asn Trp Leu Tyr Leu Ala Lys Leu Ser
             20                  25                  30

Ser Val Gly Ser Ile Ser Glu Glu Glu Thr Cys Glu Lys Leu Lys Gly
         35                  40                  45

Leu Ile Gln Arg Gln Val Gln Met Cys Lys Arg Asn Leu Glu Val Met
     50                  55                  60

Asp Ser Val Arg Arg Gly Ala Gln Leu Ala Ile Glu Glu Cys Gln Tyr
 65                  70                  75                  80

Gln Phe Arg Asn Arg Arg Trp Asn Cys Ser Thr Leu Asp Ser Leu Pro
                 85                  90                  95

Val Phe Gly Lys Val Val Thr Gln Gly Thr Arg Glu Ala Ala Phe Val
            100                 105                 110

Tyr Ala Ile Ser Ser Ala Gly Val Ala Phe Ala Val Thr Arg Ala Cys
        115                 120                 125

Ser Ser Gly Glu Leu Glu Lys Cys Gly Cys Asp Arg Thr Val His Gly
    130                 135                 140

Val Ser His Arg Ala Ser Ser Gly Gln Asp Ala Leu Thr Thr Ser Pro
145                 150                 155                 160

Thr Val Trp Pro Ser His Ser Arg Leu Trp Met Cys Gly Arg Glu Ala
                165                 170                 175

Arg Gly Pro Arg Pro Ala Glu Pro Ser 
            180                 185



<210> 2814
<211> 130
<212> PRT
<213> Homo sapiens

<400> 2814
Met Val Gly Gly Cys Leu Gly Gly Ser Lys Ser Ser His Ser Ala Trp
  1               5                  10                  15

Glu Gly Pro Ile Leu Pro Lys Cys Lys Ser Ser Arg Gly Val Thr Glu
             20                  25                  30

Leu Ala Asn Arg Leu Val Cys Leu Val Phe Leu Leu His Val Asp Ile
         35                  40                  45

Ile Leu Leu Ile Leu Leu Pro Gly Pro Pro Gln Gly Tyr Arg Lys Val
     50                  55                  60

Lys Ser Ser Pro Glu Pro Ile Met Ser Ser Leu Leu Thr Glu Gly Thr
 65                  70                  75                  80

Ala Gly Tyr Val Val Pro Pro Gly Leu Val Leu Ala Ala Gly Gly Arg
                 85                  90                  95

Cys Leu Arg Val Pro Thr Val Pro Phe Cys Phe Ser Glu Cys Ile Lys
            100                 105                 110

Gly Thr Arg Thr Cys Gln Trp Glu Ile His Pro Ser Gly Thr Gly Arg
        115                 120                 125

Glu Gly 
    130



<210> 2815
<211> 364
<212> PRT
<213> Homo sapiens

<400> 2815
Met Ala Ala Ser Gly Pro Gly Cys Arg Ser Trp Cys Leu Cys Pro Glu
  1               5                  10                  15

Val Pro Ser Ala Thr Phe Phe Thr Ala Leu Leu Ser Leu Leu Val Ser
             20                  25                  30

Gly Pro Arg Leu Phe Leu Leu Gln Gln Pro Leu Ala Pro Ser Gly Leu
         35                  40                  45

Thr Leu Lys Ser Glu Ala Leu Arg Asn Trp Gln Val Tyr Arg Leu Val
     50                  55                  60

Thr Tyr Ile Phe Val Tyr Glu Asn Pro Ile Ser Leu Leu Cys Gly Ala
 65                  70                  75                  80

Ile Ile Ile Trp Arg Phe Ala Gly Asn Phe Glu Arg Thr Val Gly Thr
                 85                  90                  95

Val Arg His Cys Phe Phe Thr Val Ile Phe Ala Ile Phe Ser Ala Ile
            100                 105                 110

Ile Phe Leu Ser Phe Glu Ala Val Ser Ser Leu Ser Lys Leu Gly Glu
        115                 120                 125

Val Glu Asp Ala Arg Gly Phe Thr Pro Val Ala Phe Ala Met Leu Gly
    130                 135                 140

Val Thr Thr Val Arg Ser Arg Met Arg Arg Ala Leu Val Phe Gly Met
145                 150                 155                 160

Val Val Pro Ser Val Leu Val Pro Trp Leu Leu Leu Gly Ala Ser Trp
                165                 170                 175

Leu Ile Pro Gln Thr Ser Phe Leu Ser Asn Val Cys Gly Leu Ser Ile
            180                 185                 190

Gly Leu Ala Tyr Gly Leu Thr Tyr Cys Tyr Ser Ile Asp Leu Ser Glu
        195                 200                 205

Arg Val Ala Leu Lys Leu Asp Gln Thr Phe Pro Phe Ser Leu Met Arg
    210                 215                 220

Arg Ile Ser Val Phe Lys Tyr Val Ser Gly Ser Ser Ala Glu Arg Arg
225                 230                 235                 240

Ala Ala Gln Ser Arg Lys Leu Asn Pro Val Pro Gly Ser Tyr Pro Thr
                245                 250                 255

Gln Ser Cys His Pro His Leu Ser Pro Ser His Pro Val Ser Gln Thr
            260                 265                 270

Gln His Ala Ser Gly Gln Lys Leu Ala Ser Trp Pro Ser Cys Thr Pro
        275                 280                 285

Gly His Met Pro Thr Leu Pro Pro Tyr Gln Pro Ala Ser Gly Leu Cys
    290                 295                 300

Tyr Val Gln Asn His Phe Gly Pro Asn Pro Thr Ser Ser Ser Val Tyr
305                 310                 315                 320

Pro Ala Ser Ala Gly Thr Ser Leu Gly Ile Gln Pro Pro Thr Pro Val
                325                 330                 335

Asn Ser Pro Gly Thr Val Tyr Ser Gly Ala Leu Gly Thr Pro Gly Ala
            340                 345                 350

Ala Gly Ser Lys Glu Ser Ser Arg Val Pro Met Pro 
        355                 360



<210> 2816
<211> 449
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (427)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (436)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2816
Met Ser Glu Met Asp Arg Arg Asn Asp Ala Trp Leu Pro Gly Glu Ala
  1               5                  10                  15

Thr Arg Gly Val Leu Arg Ala Val Ala Thr Gln Gln Arg Gly Ala Val
             20                  25                  30

Phe Val Asp Lys Glu Asn Leu Thr Met Pro Gly Leu Arg Phe Asp Asn
         35                  40                  45

Ile Gln Gly Asp Ala Val Lys Asp Leu Met Leu Arg Phe Leu Gly Glu
     50                  55                  60

Lys Ala Ala Ala Lys Arg Gln Val Leu Asn Ala Asp Ser Val Glu Gln
 65                  70                  75                  80

Ser Phe Val Gly Leu Lys Gln Leu Ile Ser Cys Arg Asn Trp Arg Ala
                 85                  90                  95

Ala Val Asp Leu Cys Gly Arg Leu Leu Thr Ala His Gly Gln Gly Tyr
            100                 105                 110

Gly Lys Ser Gly Leu Leu Thr Ser His Thr Thr Asp Ser Leu Gln Leu
        115                 120                 125

Trp Phe Val Arg Leu Ala Leu Leu Val Lys Leu Gly Leu Phe Gln Asn
    130                 135                 140

Ala Glu Met Glu Phe Glu Pro Phe Gly Asn Leu Asp Gln Pro Asp Leu
145                 150                 155                 160

Tyr Tyr Glu Tyr Tyr Pro His Val Tyr Pro Gly Arg Arg Gly Ser Met
                165                 170                 175

Val Pro Phe Ser Met Arg Ile Leu His Ala Glu Leu Gln Gln Tyr Leu
            180                 185                 190

Gly Asn Pro Gln Glu Ser Leu Asp Arg Leu His Lys Val Lys Thr Val
        195                 200                 205

Cys Ser Lys Ile Leu Ala Asn Leu Glu Gln Gly Leu Ala Glu Asp Gly
    210                 215                 220

Gly Met Ser Ser Val Thr Gln Glu Gly Arg Gln Ala Ser Ile Arg Leu
225                 230                 235                 240

Trp Arg Ser Arg Leu Gly Arg Val Met Tyr Ser Met Ala Asn Cys Leu
                245                 250                 255

Leu Leu Met Lys Asp Tyr Val Leu Ala Val Glu Ala Tyr His Ser Val
            260                 265                 270

Ile Lys Tyr Tyr Pro Glu Gln Glu Pro Gln Leu Leu Ser Gly Ile Gly
        275                 280                 285

Arg Ile Ser Leu Gln Ile Gly Asp Ile Lys Thr Ala Glu Lys Tyr Phe
    290                 295                 300

Gln Asp Val Glu Lys Val Thr Gln Lys Leu Asp Gly Leu Gln Gly Lys
305                 310                 315                 320

Ile Met Val Leu Met Asn Ser Ala Phe Leu His Leu Gly Gln Asn Asn
                325                 330                 335

Phe Ala Glu Ala His Arg Phe Phe Thr Glu Ile Leu Arg Met Asp Pro
            340                 345                 350

Arg Asn Ala Val Ala Asn Asn Asn Ala Ala Val Cys Leu Leu Tyr Leu
        355                 360                 365

Gly Lys Leu Lys Asp Ser Leu Arg Gln Leu Glu Ala Met Val Gln Gln
    370                 375                 380

Asp Pro Arg His Tyr Leu His Glu Ser Val Leu Phe Asn Leu Thr Thr
385                 390                 395                 400

Met Tyr Glu Leu Glu Ser Tyr Gly Ala Cys Arg Arg Asn Arg Pro Cys
                405                 410                 415

Trp Lys Leu Ser Pro Ala Arg Arg Gly Thr Xaa Ser Thr His Ser Ala
            420                 425                 430

Leu Ser Trp Xaa Asn Leu Leu Gln His Thr Thr Ser Glu Gly Pro Gly
        435                 440                 445

Leu 




<210> 2817
<211> 133
<212> PRT
<213> Homo sapiens

<400> 2817
Met Leu Asn Glu Arg Ala Ser Val His Thr Phe Val Glu Arg Arg Val
  1               5                  10                  15

Phe Trp Pro Glu Lys Val Lys Lys Arg His Val Gln Tyr Ala Leu Gln
             20                  25                  30

Gly Val Phe Ala Leu Phe His Ala His Ala Thr Gln Ile Gly Val Glu
         35                  40                  45

Gln Glu Gly Ala Leu Phe Cys Ser Gln Ala Ser Glu Leu Leu Ser Cys
     50                  55                  60

Gly Leu Leu Ala Val Phe Thr Arg Phe Lys Leu Arg Gly Pro His Cys
 65                  70                  75                  80

Cys Cys Ala Lys Lys Val Tyr Ser Leu Pro Arg Met Gly Pro His Thr
                 85                  90                  95

Thr Leu His Leu His Ser Thr Phe Asn Arg Val Leu Ala Val Phe Leu
            100                 105                 110

Phe Ser Phe Leu Phe Val Ser Lys Asn Leu Tyr Leu Asp Phe Asn Asn
        115                 120                 125

Gln Arg Ser Val Lys 
    130



<210> 2818
<211> 112
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (30)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (34)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (108)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2818
Met Asp Lys Phe Asn Val Thr Lys Pro Ile His Ala Leu Asn Asn Pro
  1               5                  10                  15

Ile Ile Ser Gln Phe Phe Pro Thr Leu Leu Leu Trp Ser Xaa Ser Ala
             20                  25                  30

Leu Xaa Pro Ser Ile Val Tyr Tyr Ser Thr Leu Leu Glu Ser His Trp
         35                  40                  45

Thr Lys Ser Gly Glu Asn Gln Ile Met Met Thr Lys Val Tyr Ile Phe
     50                  55                  60

Leu Ile Phe Met Val Leu Ile Leu Pro Ser Leu Gly Leu Thr Ser Leu
 65                  70                  75                  80

Asp Phe Phe Phe Arg Trp Leu Phe Asp Lys Thr Ser Ser Glu Ala Ser
                 85                  90                  95

Ile Arg Phe Gly Val Arg Leu Pro Cys Leu Thr Xaa Val Pro Ser Leu
            100                 105                 110






<210> 2819
<211> 218
<212> PRT
<213> Homo sapiens

<220>
<221> SITE
<222> (152)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (153)
<223> Xaa equals any of the naturally occurring L-amino acids

<220>
<221> SITE
<222> (163)
<223> Xaa equals any of the naturally occurring L-amino acids

<400> 2819
Met Phe Ile Gly Ala Phe Leu Ile Pro Ala Met Val Cys Gly Thr Ala
  1               5                  10                  15

Phe Phe Ile Asn Phe Ile Ala Ile Tyr Tyr His Ala Ser Arg Ala Ile
             20                  25                  30

Pro Phe Gly Thr Met Val Ala Val Cys Cys Ile Cys Phe Phe Val Ile
         35                  40                  45

Leu Pro Leu Asn Leu Val Gly Thr Ile Leu Gly Arg Asn Leu Ser Gly
     50                  55                  60

Gln Pro Asn Phe Pro Cys Arg Val Asn Ala Val Pro Arg Pro Ile Pro
 65                  70                  75                  80

Glu Lys Lys Trp Phe Met Glu Pro Ala Val Ile Val Cys Leu Gly Gly
                 85                  90                  95

Ile Leu Pro Phe Gly Ser Ile Phe Ile Glu Met Tyr Phe Ile Phe Thr
            100                 105                 110

Ser Phe Trp Ala Tyr Lys Ile Tyr Tyr Val Tyr Gly Phe Met Met Leu
        115                 120                 125

Val Leu Val Ile Leu Cys Ile Val Thr Val Cys Val Thr Ile Val Cys
    130                 135                 140

Thr Tyr Phe Leu Leu Asn Ala Xaa Xaa Ile Thr Gly Val Pro Phe Ile
145                 150                 155                 160

Gln Lys Xaa Ile Tyr Leu Leu Ser Pro Ser Arg His Gln Ala Met Asp
                165                 170                 175

Lys Phe Ser Leu Cys Cys Ile Asn Cys Asn Leu Cys Leu His Val Phe
            180                 185                 190

Leu Leu Leu Leu Phe Phe Gln Asn Lys Asp Val Trp Leu Ile Ser Asn
        195                 200                 205

Ile Ile Leu Leu Trp Ile Tyr Gly Gly Ile 
    210                 215



<210> 2820
<211> 238
<212> PRT
<213> Homo sapiens

<400> 2820
Met Leu Gly Ser Pro Cys Leu Leu Trp Leu Leu Ala Val Thr Phe Leu
  1               5                  10                  15

Val Pro Arg Ala Gln Pro Leu Ala Pro Gln Asp Phe Glu Glu Glu Glu
             20                  25                  30

Ala Asp Glu Thr Glu Thr Ala Trp Pro Pro Leu Pro Ala Val Pro Cys
         35                  40                  45

Asp Tyr Asp His Cys Arg His Leu Gln Val Pro Cys Lys Glu Leu Gln
     50                  55                  60

Arg Val Gly Pro Ala Ala Cys Leu Cys Pro Gly Leu Ser Ser Pro Ala
 65                  70                  75                  80

Gln Pro Pro Asp Pro Pro Arg Met Gly Glu Val Arg Ile Ala Ala Glu
                 85                  90                  95

Glu Gly Arg Ala Val Val His Trp Cys Ala Pro Phe Ser Pro Val Leu
            100                 105                 110

His Tyr Trp Leu Leu Leu Trp Asp Gly Ser Glu Ala Ala Gln Lys Gly
        115                 120                 125

Pro Pro Leu Asn Ala Thr Val Arg Arg Ala Glu Leu Lys Gly Leu Lys
    130                 135                 140

Pro Gly Gly Ile Tyr Val Val Cys Val Val Ala Ala Asn Glu Ala Gly
145                 150                 155                 160

Ala Ser Arg Val Pro Gln Ala Gly Gly Glu Gly Leu Glu Gly Ala Asp
                165                 170                 175

Ile Pro Ala Phe Gly Pro Cys Ser Arg Leu Ala Val Pro Pro Asn Pro
            180                 185                 190

Arg Thr Leu Val His Ala Ala Val Gly Val Gly Thr Ala Leu Ala Leu
        195                 200                 205

Leu Ser Cys Ala Ala Leu Val Trp His Phe Cys Leu Arg Asp Arg Trp
    210                 215                 220

Gly Cys Pro Arg Arg Ala Ala Ala Arg Ala Ala Gly Ala Leu 
225                 230                 235



