(WO/2007/040995) PROCESS FOR PREPARING ZOLPIDEM HEMITARTRATE AND TARTRATE POLYMORPHS
- Biblio. Data
- Description
- Claims
- National Phase
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| Latest bibliographic data on file with the International Bureau
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| IPC: | C07D 471/04 (2006.01) | |||||||||||
| Applicants: | MALLINCKRODT INC. [US/US]; 675 McDonnell Boulevard, P.O. Box 5840, St. Louis, Missouri 63134 (US) (All Except US). CHENG, Brian, K. [US/US]; (US) (US Only). | |||||||||||
| Inventor: | CHENG, Brian, K.; (US). | |||||||||||
| Agent: | COOKE, Christine, R. et al.; Mallinckrodt Inc., 675 McDonnell Boulevard, P.O. Box 5840, St. Louis, Missouri 63134 (US). | |||||||||||
| Priority Data: |
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| Title: | PROCESS FOR PREPARING ZOLPIDEM HEMITARTRATE AND TARTRATE POLYMORPHS | |||||||||||
| Abstract: | A method for preparing a polymorph of a hemitartrate salt of a compound having the structure: comprising dissolving a free base form of the compound in a liquid medium comprising an alcohol and a tartrate derivative to form a solution comprising the compound, the alcohol, and the tartrate derivative; heating the solution to a temperature sufficient to dissolve the compound and the tartrate derivative; and cooling the solution to a temperature sufficient to precipitate the hemitartrate salt of the compound. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
