(WO/2005/053654) CONTROLLED RELEASE DOSAGE FORMS OF AZITHROMYCIN

(WO/2005/053654) CONTROLLED RELEASE DOSAGE FORMS OF AZITHROMYCIN

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2005/053654   International Application No.:  PCT/IB2004/003889
Publication Date:16.06.2005 International Filing Date:24.11.2004
Chapter 2 Demand Filed: 14.12.2004
IPC: A61K 31/7052 (2006.01), A61K 9/16 (2006.01)
Applicants:PFIZER PRODUCTS INC. [US/US]; Eastern Point Road, Groton, CT 06340 (US) (All Except US).
APPEL, Leah, Elizabeth [US/US]; (GB) (US Only).
CREW, Marshall, David [US/US]; (GB) (US Only).
FRIESEN, Dwayne, Thomas [US/US]; (GB) (US Only).
NEWBOLD, David, Dixon [US/US]; (GB) (US Only).
RAY, Roderick, Jack [US/US]; (GB) (US Only).
Inventors:APPEL, Leah, Elizabeth; (GB).
CREW, Marshall, David; (GB).
FRIESEN, Dwayne, Thomas; (GB).
NEWBOLD, David, Dixon; (GB).
RAY, Roderick, Jack; (GB).
Agent:WOOD, David, J. et al.; Pfizer Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ (GB).
Priority Data:
60/527,317 04.12.2003 US
Title: CONTROLLED RELEASE DOSAGE FORMS OF AZITHROMYCIN
Abstract: A process for forming multiparticulates of azithromycin and a controlled release dosage form comprising multiparticulates of azithromycin and a pharmaceutically acceptable excipient are disclosed. The dosage form decreases the incidence and/or severity of GI side effects relative to currently available immediate release azithromycin dosage forms that deliver an equivalent dose. The dosage forms operate by effecting azithromycin release at a rate sufficiently slow to ameliorate side effects, yet sufficiently fast to achieve good biovailability.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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