(WO/2003/045335) STEM CELL SCREENING AND TRANSPLANTATION THERAPY FOR HIV INFECTION
- Biblio. Data
- Description
- Claims
- National Phase
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| Latest bibliographic data on file with the International Bureau
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| IPC: | C12N 5/06 (2006.01), A61K 35/12 (2006.01) | |||||||||||
| Applicants: | STEMCYTE, INC. [US/US]; 400 Rolyn Place
Arcadia, CA 91006 (US) (All Except US). CHOW, Robert [US/US]; (US) (US Only). RODGERSON, Denis, O. [US/US]; (US) (US Only). PUNZALAN, Rubio, R. [US/US]; (US) (US Only). PETZ, Lawrence, D. [US/US]; (US) (US Only). | |||||||||||
| Inventors: | CHOW, Robert; (US). RODGERSON, Denis, O.; (US). PUNZALAN, Rubio, R.; (US). PETZ, Lawrence, D.; (US). | |||||||||||
| Agent: | KELLY, Beth, L. et al.; Townsend And Townsend And Crew LLP Two Embarcadero Center 8th Floor San Francisco, CA 94111-3834 (US). | |||||||||||
| Priority Data: |
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| Title: | STEM CELL SCREENING AND TRANSPLANTATION THERAPY FOR HIV INFECTION | |||||||||||
| Abstract: | This invention provides methods for preventing or treating any disease arising from HIV infection, including AIDS and AIDS-related complex (ARC). The method comprises screening a plurality of donors to identify stem cells with a beneficial gene or genes and then transplanting the therapeutic stem cells into a patient. In preferred embodiments, the beneficial gene encodes a polymorphism that renders cells refractory to HIV infection. The polymorphism may be for a gene that encodes a ligand of a receptor for HIV entry, a product of the HLA complex, or a receptor for HIV entry. The invention also provides isolated populations of stem cells with beneficial genes for resisting infections. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
