(WO/1998/050361) SYNTHESIS OF PHARMACEUTICALLY USEFUL PYRIDINE DERIVATIVES
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| Latest bibliographic data on file with the International Bureau
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| IPC: | C07D 213/61 (2006.01), C07D 213/68 (2006.01), C07D 213/803 (2006.01), C07D 213/81 (2006.01) | |||||||||||
| Applicants: | PDi-RESEARCH LABORATORIES, INC. [CA/CA]; P.O. Box 433, Station A, Richmond Hill, Ontario L4C 4Y8 (CA) (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, HU, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW only). ZOGHBI, Michel [CA/CA]; (CA) (US Only). CHEN, Liquin [CA/CA]; (CA) (US Only). | |||||||||||
| Inventors: | ZOGHBI, Michel; (CA). CHEN, Liquin; (CA). | |||||||||||
| Agent: | HUGHES, ETIGSON; Suite 200, 175 Commerce Valley Drive West, Thornhill, Ontario L3T 7P6 (CA). | |||||||||||
| Priority Data: |
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| Title: | SYNTHESIS OF PHARMACEUTICALLY USEFUL PYRIDINE DERIVATIVES | |||||||||||
| Abstract: | A process is provided for the preparation of compounds of formula (I) useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R?1¿=H or CH¿3?, R?2¿=H or CH¿3?, R?3¿=Alkoxy (1-4C), OCH¿2?CF¿3?, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula (I) employs a free radical reaction to functionalize the 2-position. | |||||||||||
| Designated States: |
AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW. African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
