(WO/1998/002149) USE OF IDEBENONE AND ANALOGUES AGAINST BETA AMYLOID INDUCED CYTOTOXICITY
- Biblio. Data
- Description
- Claims
- National Phase
- Notices
- Documents
| Latest bibliographic data on file with the International Bureau
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| IPC: | A61K 31/047 (2006.01), A61K 31/122 (2006.01) | ||||||||||||||||||
| Applicants: | TAKEDA CHEMICAL INDUSTRIES, LTD. [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 541 (JP) (All Except US). MIYAMOTO, Masaomi [JP/JP]; (JP) (US Only). HIRAI, Keisuke [JP/JP]; (JP) (US Only). GOTO, Giichi [JP/JP]; (JP) (US Only). | ||||||||||||||||||
| Inventors: | MIYAMOTO, Masaomi; (JP). HIRAI, Keisuke; (JP). GOTO, Giichi; (JP). | ||||||||||||||||||
| Agents: | ASAHINA, Tadao et al.; Osaka Plant of Takeda Chemical Industries, Ltd., 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 532 (JP). ELKINGTON AND FIFE; Prospect House, 8 Pembroke Road, Sevenoaks, Kent TN13 1XR (GB). | ||||||||||||||||||
| Priority Data: |
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| Title: | USE OF IDEBENONE AND ANALOGUES AGAINST BETA AMYLOID INDUCED CYTOTOXICITY | ||||||||||||||||||
| Abstract: | A compound of formula (I) or (II) wherein R?1¿ represents a lower alkyl; R?2¿ represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R?3¿ and R?4¿ each represents an optionally substituted lower alkyl or a lower alkoxy, or R?3¿ and R?4¿ form, taken together, an optionally substituted butadienylene; and X?1¿ and X?2¿ each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of $g(b)-amyloid protein. | ||||||||||||||||||
| Designated States: |
AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HU, IL, IS, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU. African Regional Intellectual Property Org. (ARIPO) (GH, KE, LS, MW, SD, SZ, UG, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG). | ||||||||||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
