(WO/1992/005787) DRUG THERAPY FOR ALCOHOL ABUSERS

(WO/1992/005787) DRUG THERAPY FOR ALCOHOL ABUSERS

WO 1992005787 19920416 CLAIMS:

1. A method of treating alcoholism comprising the step of: administering a composition to an alcoholic, said composition consisting of a therapeutically effective dosage of an agent that induces adverse reactions to alcohol ingestion and a medication that is similar to alcohol in its affect on the neurological system of the alcoholic.

2. . The method of claim 1, wherein said medication is selected from the group consisting of: sedatives, pain medications, and addictive, anti-anxiety medications.

3. The method of claim 1, wherein said medication is habit-forming.

4. The method of claim 3, wherein said habit- forming medication is an anti-anxiety drug.

5. The method of claim 4, wherein said habit- forming medication is a benzodiazepine-related compound.

6. The method of claim 5, wherein said benzodiazepine-related compound is diazepam.

7. The method of claim 1, wherein said medication is librium.

8. The method of claim 1, wherein said agent is calcium carbamide.

9. The method of claim 1, wherein said composition includes 125 mg of disulfiram.

10. The method of claim 1, wherein said composition includes 10 mg of diazepam.

11. The method of claim 1, wherein the step of administering said composition is undertaken two to four times a day.

12. A method of treating an alcoholic patient following a period of detoxification to encourage abstinence from alcohol, comprising the steps of: providing the alcoholic patient with a therapeutically effective composition of an agent that induces adverse reactions to alcohol ingestion and a medication that is similar to alcohol in its effect on the neurological system; and

reinforcing the alcoholic patient to comply with treatment by the presence of a medication that is similar to alcohol in its effect on the neurological system, whereby the patient desires to ingest the disulfiram and the medication simultaneously.

13. The method of claim 12, wherein said medication is selected from the group consisting of: sedatives, pain medications, and addictive, anti-anxiety medications.

14. The method of claim 12, wherein said medication is habit-forming.

15. The method of claim 14, wherein said habit- forming medication is an anti-anxiety drug.

16. The method of claim 15, wherein said habit- forming medication is a benzodiazepine-related compound.

17. The method of claim 16, wherein said benzodiazepine-related compound is diazepam.

18. The method of claim 12, wherein said medication is librium.

19. The method of claim 12, wherein said agent is calcium carbamide.

20. The method of claim 12, wherein said composition includes 125 mg of disulfiram.

21. The method of claim 12, wherein said composition includes 10 mg of diazepam.

22. The method of claim 12, wherein the step of administering said composition is undertaken two to four times a day.

23. A composition for treating alcoholism comprising: a therapeutically effective dosage of an agent that induces adverse reactions to alcohol ingestion and a medication that is similar to

alcohol in its affect on the neurological system.

24. The composition of claim 23, wherein said medication is selected from the group of depressants consisting of: sedatives, pain medications, and addictive, anti-anxiety medications.

25. The composition of claim 23, wherein said medication is habit-forming.

26. The composition of claim 25, wherein said habit-forming medication is an anti-anxiety drug.

27. The composition of claim 26, wherein said habit-forming medication is a benzodiazepine-related compound.

28. The composition of claim 27, wherein said benzodiazepine-related compound is diazepam.

29. The composition of claim 23, wherein said medication is librium.

30. The composition of claim 23, wherein said agent is calcium carbamide.

31. The composition of claim 23, wherein said composition includes 125 mg of disulfiram.

32. The composition of claim 23, wherein said composition includes 10 mg of diazepam.

33. A composition for treatment of alcoholics after a period of sobriety and stability, said composition comprising a therapeutically effective dosage of an agent that indices adverse reactions to alcohol ingestion and a medication that is similar to alcohol in its affect on the neurological system.

34. The composition of claim 33, wherein said medication is selected from the group of depressants consisting of: sedatives, pain medications and additives, anxiety medications.

35. The composition of claim 33, wherein said medication is habit-forming.

36. The composition of claim 35, wherein said habit-forming medication is an anti-anxiety drug.

37. The composition of claim 36, wherein said habit-forming medication is a benzodiazepine-related compound.

38. The compound of claim 37, wherein said benzodiazepine-related compound is diazepam.

39. The composition of claim 33, wherein said medication is librium.

40. The composition of claim 33, wherein said agent is calcium carbamide.

41. The composition of claim 33, wherein said composition includes 125 mg of disulfiram and between 2 mg and 5 mg of diazepam.

42. A composition for inducing alcohol abstinence in a detoxified alcoholic, comprising: an agent that induces adverse reactions to alcohol ingestion and a medication that is similar to alcohol in its affect on the neurological system.

43. The composition of claim 42, wherein said medication is selected from the group of depressants consisting of: sedatives, pain-medications, and addictive, anti-anxiety medications.

44. The composition of claim 42, wherein said medication is habit-forming.

45. The composition of claim 44, wherein said habit-forming medication is an anti-anxiety drug.

46. The composition of claim 44, wherein said habit-forming medication is a benzodiazepine-related compound.

47. The composition of claim 46, wherein said benzodiazepine-related compound is diazepam.

48. The composition of claim 42, wherein said composition includes 125 mg of disulfiram and 10 mg of diazepam.

49. The method of claim 1, wherein said agent is disulfiram.

50. The method of claim 12, wherein said agent is disulfiram.

51. The composition of claim 23, wherein said agent is disulfiram.

52. The composition of claim 33, wherein said agent is disulfiram.

53. The composition of claim 43, wherein said agent s disulfiram.

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