(WO/2008/057481) VENTRICULAR ASSIST DEVICE CAPABLE OF IMPLANTATION OF STEM CELLS
- Biblio. Data
- Description
- Claims
- National Phase
- Notices
- Documents
| Latest bibliographic data on file with the International Bureau
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| IPC: | A61M 1/10 (2006.01), C12N 5/06 (2006.01), A61M 1/12 (2006.01) | |||||||||||
| Applicants: | THE UNIVERSITY OF UTAH [US/US]; 615 Arapeen Drive, Suite 310, Salt Lake City, UT 84108 (US) (All Except US). BULL, David, A. [US/US]; (US) (US Only). CONNORS, Rafe, C. [US/US]; (US) (US Only). ERICKSON, Harold, M. [US/US]; (US) (US Only). YOCKMAN, James [US/US]; (US) (US Only). KIM, Sung, Wan [US/US]; (US) (US Only). | |||||||||||
| Inventors: | BULL, David, A.; (US). CONNORS, Rafe, C.; (US). ERICKSON, Harold, M.; (US). YOCKMAN, James; (US). KIM, Sung, Wan; (US). | |||||||||||
| Agent: | CHWANG, Ling, T. et al.; Jackson Walker L.L.P., 901 Main Street, Suite 6000, Dallas, TX 75202 (US). | |||||||||||
| Priority Data: |
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| Title: | VENTRICULAR ASSIST DEVICE CAPABLE OF IMPLANTATION OF STEM CELLS | |||||||||||
| Abstract: | A biologic ventricular assist device that also has the capability to capture, grow, and administer stem cells to regenerate and restore damaged myocardium in the heart. The device works in conjunction with a traditional ventricular assist device and possesses an additional external path or tube that is in-line with the path of the ventricular assist device. The external path allows for the administration of stem cells, genes, genetically modified cells or other therapeutic biologic or pharmacologic agents, as well as leading to a stem cell collecting accessory (14) that captures circulating stem cells. The stem cell collecting accessory is also associated with a chamber (39) for culturing the captured stem cells. The cultured stem cells can be delivered back to the heart by an electro-mechanical or ultrasound/echocardiographic delivery system that runs through the external path back into the ventricular assist device and allows for the delivery of the stem cells, or other therapeutic biologic or pharmacologic agents, directly into the internal chambers of the heart. Administering the stem cells, genes, genetically modified cells or other therapeutic biologic or pharmacologic agents, either alone or in combination, to the heart allows the myocardium to regenerate and repair itself even while the heart is attached to the ventricular assist device, ultimately allowing the heart to regenerate, recover and allow the VAD to be removed. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
