(WO/2008/045107) BOTULINUM NANOEMULSIONS

(WO/2008/045107) BOTULINUM NANOEMULSIONS

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2008/045107   International Application No.:  PCT/US2006/046236
Publication Date:17.04.2008 International Filing Date:01.12.2006
IPC: A61K 9/00 (2006.01)
Applicants:UNIVERSITY OF MASSACHUSETTS LOWELL [US/US]; 1 University Avenue, Lowell, Massachusetts 01854 (US) (All Except US).
EDELSON, Jonathan [US/US]; (US) (US Only).
NICOLOSI, Robert [US/US]; (US) (US Only).
Inventors:EDELSON, Jonathan; (US).
NICOLOSI, Robert; (US).
Agent:DECONTI, Giulio, A., Jr.; Lahive & Cockfield, LLP, One Post Office Square, Boston, MA 02109-2127 (US).
Priority Data:
60/741,139 01.12.2005 US
Title: BOTULINUM NANOEMULSIONS
Abstract: The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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