(WO/2007/115095) SYSTEMS AND METHODS FOR USING MOLECULAR NETWORKS IN GENETIC LINKAGE ANALYSIS OF COMPLEX TRAITS
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| Latest bibliographic data on file with the International Bureau
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| IPC: | G01N 33/48 (2006.01), C12Q 1/68 (2006.01) | |||||||||||||||
| Applicants: | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK [US/US]; 116th Street and Broadway, New York, NY 10027 (US) (All Except US). IOSSIFOV, Ivan [BD/US]; (US) (US Only). ZHENG, Tian [CN/US]; (US) (US Only). RZHETSKY, Andrey [US/US]; (US) (US Only). | |||||||||||||||
| Inventors: | IOSSIFOV, Ivan; (US). ZHENG, Tian; (US). RZHETSKY, Andrey; (US). | |||||||||||||||
| Agent: | RAGUSA, Paul, A. et al.; Baker Botts L.l.p., 30 Rockefeller Plaza, New York, NY 10112-4498 (US). | |||||||||||||||
| Priority Data: |
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| Title: | SYSTEMS AND METHODS FOR USING MOLECULAR NETWORKS IN GENETIC LINKAGE ANALYSIS OF COMPLEX TRAITS | |||||||||||||||
| Abstract: | The present disclosed subject matter relates to methods of using molecular networks in whole genome genetic linkage analysis of complex inherited disorders, including determining gene-specific linkage probability values for one or more genes represented in a predetermined molecular interaction network. The present disclosed subject matter further relates to methods of identifying one or more gene that is associated with one or more heritable diseases, and methods of diagnosing the heritable diseases. | |||||||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
