(WO/2008/011609) COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2
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| Latest bibliographic data on file with the International Bureau
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| Pub. No.: | WO/2008/011609 | International Application No.: | PCT/US2007/074045 | |||
| Publication Date: | 24.01.2008 | International Filing Date: | 20.07.2007 |
| IPC: | C12N 15/38 (2006.01), A61K 31/70 (2006.01), A61K 39/245 (2006.01), C07K 16/08 (2006.01), C12N 15/86 (2006.01), G01N 33/569 (2006.01) | |||||
| Applicants: | VICAL INCORPORATED [US/US]; 10390 Pacific Center Court, San Diego, CA 92121 (US) (All Except US). MARGALITH, Michal [US/US]; (US) (US Only). VILALTA, Adrian [US/US]; (US) (US Only). KOELLE, David, M. [US/US]; (US) (US Only). DONG, Lichun [US/US]; (US) (US Only). UNIVERSITY OF WASHINGTON [US/US]; 8321 Ne 187th Way, Seattle, WA 98195 (US) (All Except US). | |||||
| Inventors: | MARGALITH, Michal; (US). VILALTA, Adrian; (US). KOELLE, David, M.; (US). DONG, Lichun; (US). | |||||
| Agent: | DOW, Karen, B. et al.; DLA Piper LLP (US), 4365 Executive Drive, Suite 1100, San Diego, CA 92121 (US) . | |||||
| Priority Data: |
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| Title: | COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2 | |||||
| Abstract: | The present invention relates to prophylactic and therapeutic compositions and methods for inducing an immune response to herpes simplex virus type 2 (HSV-2), in particular by introducing and expressing in a vertebrate a DNA vaccine encoding at least one of the HSV-2 proteins such as gD, VP11/12, VP 13/14 and/or VP22. Formulations based on Vaxfectin (TM) adjuvant and poloxamer were evaluated for their ability to boost the immune response to the HSV DNA vaccines. | |||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). |
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
