(WO/2007/106435) CLEAVABLE VACCINES COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
- Biblio. Data
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| Latest bibliographic data on file with the International Bureau
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| IPC: | C12N 15/63 (2006.01), A61K 38/00 (2006.01) | |||||||||||
| Applicants: | UNIVERSITY OF CALIFORNIA [US/US]; Office of Intellectual Property, 10920 Wilshire Blvd., Los Angeles, CA 90024-1406 (US) (All Except US). TIMMERMAN, John, M. David Geffen School of Medicine at UCLA [US/US]; (US) (US Only). | |||||||||||
| Inventor: | TIMMERMAN, John, M. David Geffen School of Medicine at UCLA; (US). | |||||||||||
| Agent: | SUNDBY, Suzannah, K; SMITH, GAMBRELL & RUSSELL, LLP, 1130 Connecticut Ave., NW, #1130, Washington, DC, 20036 (US). | |||||||||||
| Priority Data: |
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| Title: | CLEAVABLE VACCINES COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | |||||||||||
| Abstract: | The invention relates to methods for making vaccines using linkages that are cleavable under lysosomal processing conditions, and vaccine compositions obtained therefrom. In some embodiments, the vaccines comprise a tumor antigen, an immunogenic carrier and a linker covalently linking the tumor antigen and the immunogenic carrier by a thio ether linkage. Vaccines of preferred embodiments can be used against a cellular proliferative disease that is characterized by the tumor antigen. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
