(WO/2003/086292) USE OF NA,K-ATPASE A-AND B-SUBUNITS IN BLADDER CANCER DETECTION AND DRUG SCREENING
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| Latest bibliographic data on file with the International Bureau
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| IPC: | G01N 33/53 (2006.01) | ||||||||||||||||||
| Applicants: | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 12th Floor, Oakland, CA 94607-5200 (US) (All Except US). RAJASEKARAN, Ayyappan K. [IN/US]; (US) (US Only). RAJASEKARAN, Sigrid A. [DE/US]; (US) (US Only). | ||||||||||||||||||
| Inventors: | RAJASEKARAN, Ayyappan K.; (US). RAJASEKARAN, Sigrid A.; (US). | ||||||||||||||||||
| Agent: | SHERWOOD, Pamela, J.; Bozicevic, Field & Francis LLP, 1900 University Avenue, Suite 200, East Palo Alto, CA 94303 (US). | ||||||||||||||||||
| Priority Data: |
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| Title: | USE OF NA,K-ATPASE A-AND B-SUBUNITS IN BLADDER CANCER DETECTION AND DRUG SCREENING | ||||||||||||||||||
| Abstract: | Methods are provided for determining the malignancy of cells in a bladder carcinoma sample. Expression patterns of Na,K-ATPase &agr; and &bgr; subunits are shown to be associated with recurrence risk in these cancers. Detection of Na,K-ATPase &agr; and &bgr; subunits expression in bladder carcinomas provides a useful diagnostic for predicting patient prognosis and probability of drug effectiveness. Na,K-ATPase &agr; and &bgr; subunits provide a target for drug screening. | ||||||||||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | ||||||||||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
