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(WO/2008/025016) SYSTEMS AND METHODS FOR HIGH-THROUGHPUT, MINIMALLY-INVASIVE RADIATION BIODOSIMETRY
- Biblio. Data
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| Latest bibliographic data on file with the International Bureau
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| IPC: | A61B 5/00 (2006.01) | |||||||||||||||
| Applicants: | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US/US]; Office of the General Counsel, 412 Low Memorial Library, Mail Code 4308, 535 West 116th Street, New York, New York 10027 (US) (All Except US). GEORGETOWN UNIVERSITY [US/US]; 3970 Reservoir Rd., NW, Washington, District Of Columbia 20057-1468 (US) (All Except US). NATIONAL CANCER INSTITUTE [US/US]; 9000 Rockville Pike, Bethesda, Maryland 20892 (US) (All Except US). UNIVERSITY OF BERN [CH/CH]; Murtenstr. 35, CH-3010 Bern (CH) (All Except US). SIONEX CORPORATION [US/US]; 8A Preston Court, Bedford, Massachusetts 01730 (US) (All Except US). FORNACE, Albert J. [US/US]; (US) (US Only). IDLE, Jeff [GB/CH]; (CH) (US Only). NAZAROV, Erkinjon G. [UZ/US]; (US) (US Only). GONZALEZ, Frank [US/US]; (US) (US Only). COY, Stephen [US/US]; (US) (US Only). | |||||||||||||||
| Inventors: | FORNACE, Albert J.; (US). IDLE, Jeff; (CH). NAZAROV, Erkinjon G.; (US). GONZALEZ, Frank; (US). COY, Stephen; (US). | |||||||||||||||
| Agent: | BOCK, Joel N.; Sonnenschein Nath & Rosenthal LLP, Post Office Box 061080, Wacker Drive Station, Sears Tower, Chicago, Illinois 60606-1080 (US). | |||||||||||||||
| Priority Data: |
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| Title: | SYSTEMS AND METHODS FOR HIGH-THROUGHPUT, MINIMALLY-INVASIVE RADIATION BIODOSIMETRY | |||||||||||||||
| Abstract: | A method for obtaining a sample, determining the sample's metabolomic signature, comparing that signature to at least one known metabolomic signature, and quantifying the radiation exposure of the sample Sample sources may include blood, blood plasma, sweat, urine, sebum, saliva, or cells, or a combination thereof The method may utilize samples obtained noninvasively The method may be capable of high throughput, 50, 100, 1000, 10,000, 100,000, or more samples per hour The method may utilize samples from mice, humans, or other mammals The method may utilize chromatography, mass spectroscopy, or radiofrequency differential ion mobility spectrometry analysis, or a combination thereof The method may employ software for comparing the metabolomic signature of the sample with at least one known radiation exposure metabolomics signature | |||||||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
