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(WO/2008/008229) DE NOVO FORMATION AND REGENERATION OF VASCULARIZED TISSUE FROM TISSUE PROGENITOR CELLS AND VASCULAR PROGENITOR CELLS

(WO/2008/008229) DE NOVO FORMATION AND REGENERATION OF VASCULARIZED TISSUE FROM TISSUE PROGENITOR CELLS AND VASCULAR PROGENITOR CELLS

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2008/008229   International Application No.:  PCT/US2007/015293
Publication Date:17.01.2008 International Filing Date:10.07.2007
IPC: A61F 2/01 (2006.01), C12N 5/00 (2006.01), C12N 5/08 (2006.01), C12P 1/00 (2006.01)
Applicants:COLUMBIA UNIVERSITY [US/US]; 412 Low Memorial Library, 535 West 116th Street, Mc4308, New York, NY 10027 (US) (All Except US).
MAO, Jeremy, J. [CA/US]; (US) (US Only).
Inventor:MAO, Jeremy, J.; (US).
Agent:BOCK, Joel, N. et al.; Sonnenschein Nath & Rosenthal Llp, Po Box 061080, Wacker Drive Station, Sears Tower, Chicago, IL 60606-1080 (US).
Priority Data:
60/824,597 05.09.2006 US
60/819,833 10.07.2006 US
Title: DE NOVO FORMATION AND REGENERATION OF VASCULARIZED TISSUE FROM TISSUE PROGENITOR CELLS AND VASCULAR PROGENITOR CELLS
Abstract: It has been discovered that vascularized tissue or organs can be engineered by combined actions of tissue progenitor cells and vascular progenitor cells. Provided herein are compositions and methods directed to engineered vascularized tissue or organs formed by introducing tissue progenitor cells and vascular progenitor into or onto a biocompatible scaffold of matrix material. Also provided are methods of treating tissue defects via grafting of such compositions into subjects in need thereof.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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