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(WO/2008/011559) SYNTHETIC LUNG SURFACTANT AND USE THEREOF
- Biblio. Data
- Description
- Claims
- National Phase
- Notices
- Documents
| Latest bibliographic data on file with the International Bureau
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| IPC: | C07F 9/02 (2006.01) | |||||||||||
| Applicants: | UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Avenue, Box OTT, Rochester, NY 14642 (US) (All Except US). UNIVERSITY OF GUELPH [CA/CA]; 50 Stone Road East, Guelph, ON N1G 2W1 (CA) (All Except US). THE LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER [US/US]; 1124 W. Carson Street, Torrance, CA 90502 (US) (All Except US). NOTTER, Robert, H. [US/US]; (US) (US Only). WANG, Zhengdong [US/US]; (US) (US Only). SCHWAN, Adrian, L. [CA/CA]; (CA) (US Only). WANG, Zhongyi [CN/CA]; (CA) (US Only). DAVY, Jason, A. [CA/CA]; (CA) (US Only). WARING, Alan, J. [US/US]; (US) (US Only). WALTHER, Frans [US/US]; (US) (US Only). GORDON, Larry, M. [US/US]; (US) (US Only). | |||||||||||
| Inventors: | NOTTER, Robert, H.; (US). WANG, Zhengdong; (US). SCHWAN, Adrian, L.; (CA). WANG, Zhongyi; (CA). DAVY, Jason, A.; (CA). WARING, Alan, J.; (US). WALTHER, Frans; (US). GORDON, Larry, M.; (US). | |||||||||||
| Agent: | MERKEL, Edwin, V. et al.; Nixon Peabody Llp, Clinton Square, P.O.Box 31051, Rochester, NY 14603-1051 (US). | |||||||||||
| Priority Data: |
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| Title: | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | |||||||||||
| Abstract: | The present invention relates to synthetic lung surfactant compositions that contain one or more of phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active proteins or peptides, more preferably a combination of at least two or all three of these materials. Novel phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active peptides are also disclosed herein. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue, to prepare synthetic peptides for use in the surfactant compositions, and to deliver therapeutic agents are also disclosed. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
