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Search result: 15 of 119 |
(WO/2007/134142) METHODS AND COMPOSITIONS FOR IDENTIFYING AND USING P21-REGULATED PROTEINS
- Biblio. Data
- Description
- Claims
- National Phase
- Notices
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| Latest bibliographic data on file with the International Bureau
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| IPC: | A61K 48/00 (2006.01) | |||||||||||
| Applicants: | UNIVERSITY COLLEGE DUBLIN [IE/IE]; National University of Ireland, Belfield, Dublin 4 (IE) (All Except US). GALLAGHER, William [IE/IE]; (IE) (US Only). O'CONNOR, Darran [IE/IE]; (IE) (US Only). CURRID, Caroline [IE/IE]; (IE) (US Only). RONINSON, Igor [US/US]; (US) (US Only). | |||||||||||
| Inventors: | GALLAGHER, William; (IE). O'CONNOR, Darran; (IE). CURRID, Caroline; (IE). RONINSON, Igor; (US). | |||||||||||
| Agent: | LEONARDO, Mark, S.; Brown Rudnick Berlack Israels LLP, One Financial Center, Boston, MA 02111 (US). | |||||||||||
| Priority Data: |
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| Title: | METHODS AND COMPOSITIONS FOR IDENTIFYING AND USING P21-REGULATED PROTEINS | |||||||||||
| Abstract: | This disclosure identifies p21-regulated proteins that may be used to induce anti- apoptotic and/or mitogenic cellular effects, both paracrine and within the p21-expressing cell itself. Three proteins released from HT- 1080 human fibrosarcoma cells displaying inducible p21 expression were identified; β-2-microglobulin, cystatin C, and pro-platelet basic protein. The disclosure also provides therapeutic compositions, methods for using, and methods for identifying p21-regulated proteins. | |||||||||||
| Designated States: |
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). | |||||||||||
| Publication Language: | English (EN) |
| Filing Language: | English (EN) |
