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(WO/2007/094854) RNA VIRUS VACCINES AND METHODS

(WO/2007/094854) RNA VIRUS VACCINES AND METHODS

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2007/094854   International Application No.:  PCT/US2006/047696
Publication Date:23.08.2007 International Filing Date:14.12.2006
Chapter 2 Demand Filed: 14.12.2006
IPC: A61K 39/12 (2006.01), C12Q 1/70 (2006.01)
Applicants:THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA [US/US]; 660 Parrington Oval, Room 119, Norman, OK 73019 (US).
DITTMER, Dirk, P. [US/US]; (US) (US Only).
FLOYD, Robert, A. [US/US]; (US) (US Only).
Inventors:DITTMER, Dirk, P.; (US).
FLOYD, Robert, A.; (US).
Agent:CORBETT, Christopher, W. et al.; Dunlap, Codding & Rogers, P.c., P.o. Box 16370, Oklahoma City, OK 73113 (US).
Priority Data:
60/750,859 14.12.2005 US
Title: RNA VIRUS VACCINES AND METHODS
Abstract: The invention is a vaccine, and method of vaccination, against RNA viruses, including RNA viruses in the family Flaviviridae, which includes for example West Nile Virus, Yellow fever virus, Dengue fever virus, Hepatitis C virus, Pestiviruses, Bovine viral diarrhea virus, and Classical Swine fever virus, wherein the vaccine comprises the RNA virus or immunogenic portions thereof, which have been treated with and rendered non-pathogenic by a phenothiazine dye and visible light, the phenothiazine dyes, including, but not limited to, Methylene Blue (MB), Methylene Green, 1 -methyl MB, 1,9-dimethyl MB, Azure A, Azure B, Azure C, thionine, and toluidine blue, or by squalene. The invention includes novel strains of WNV for use in producing a vaccine, and novel primers and their use in recognizing and amplifying all of or portions of the WNV genome for diagnosing WNV infections, for quality control of the vaccine, or for identifying the presence of WNV in blood or blood products.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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