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(WO/2007/103365) RANDOM RNAI LIBRARIES, METHODS OF GENERATING SAME, AND SCREENING METHODS UTILIZING SAME

(WO/2007/103365) RANDOM RNAI LIBRARIES, METHODS OF GENERATING SAME, AND SCREENING METHODS UTILIZING SAME

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2007/103365   International Application No.:  PCT/US2007/005682
Publication Date:13.09.2007 International Filing Date:06.03.2007
IPC: C12Q 1/68 (2006.01), C40B 50/00 (2006.01)
Applicants:THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street, Suite 200, Philadelphia, PA 19104-6283 (US) (All Except US).
WILSON, Robert, B. [US/US]; (US) (US Only).
WANG, Yongping [CN/US]; (US) (US Only).
Inventors:WILSON, Robert, B.; (US).
WANG, Yongping; (US).
Agent:COHEN, Mark, S.; Pearl Cohen Zedek Latzer, Llp, 1500 Broadway, 12th Floor, New York, NY 10036 (US).
Priority Data:
60/779,409 07.03.2006 US
Title: RANDOM RNAI LIBRARIES, METHODS OF GENERATING SAME, AND SCREENING METHODS UTILIZING SAME
Abstract: This invention provides expression vectors for a ribonucleic acid (RNA) molecule comprising a double-stranded region of random sequence, sets and libraries of same, methods of generating same, and methods for identifying an RNA therapeutic or RNA molecule that has an ability to affect a biological parameter, for identifying a drug target for a disease or disorder of interest, and for identifying a variant of an RNA molecule that has an altered ability to affect a biological parameter of interest.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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