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| Title |
Pub. Date |
Int. Class |
App. Num |
Applicant |
| 76. |
(WO 2008/014722) PRENYL FLAVONOIDS,THEIR PREPARATION AND USE
|
07.02.2008
|
C07H 17/07
|
PCT/CN2007/070375
|
TOPHARMAN SHANGHAI CO., LTD.
|
| |
Prenyl flavonoids, their preparation and use. The prenyl flavonoids are shown by formula I,in which ring A is five or six carbon ring glucide, or disaccharide; R is substitute of hydroxy on ring A selected from H,COC<sb>m</sb>H<sb>2m+1</sb>(m is natural number from 1 to 6) and C<sb>m</sb>H<sb>2m+1</sb>(m is natural number from 1 to 6); n is natural number from 1 to 7; R<sb>1</sb> is selected from H,C<sb>1</sb>-C<sb>6</sb>alkyl,C<sb>3</sb>-C<sb>8</sb>cycloalkyl,C<sb>2</sb>-C<sb>6</sb>alkenyl,C<sb>2</sb>-C...
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| 77. |
(WO 2008/014668) ATTENUATED SALMONELLA CARRYING EFFECTIVE PLASMID AND ITS ANTITUMORIGENIC USE
|
07.02.2008
|
C12N 1/21
|
PCT/CN2007/002157
|
JILIN UNIVERSITY
|
| |
The present invention relates to attenuated salmonella and its use in treating tumors. The present invention belongs to biological technique field. The present invention discloses the constructions of pH1Si-Stat3, pGRIM-19, and pGRIM-19-Si-Stat3 recombinant plasmid, which coexpresses GRIM-19 and siRNA-Stat3. An attenuation salmonella electrotransformated with the recombinant plasmid is disclosed. The coexpression of GRIM-19 and siRNA-Stat3 has a good synergistic inhibition effect on the growth and metastases of tumors in the experiment in vivo. Attenuated salmonella has phagorytosis effect on tumors, and the progenitive specificity in tumortissue is more than 1000 times as that in normal tissue. The attenuated salmonella carrying effective ...
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| |
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| 78. |
(WO 2008/014665) INTERVERTEBRAL DISK TRANSPLANT AND IMPLANTATION METHOD
|
07.02.2008
|
A61L 27/54
|
PCT/CN2007/002024
|
THE UNIVERSITY OF HONG KONG
|
| |
A natural spinal disk including adjacent vertebral structures is removed from a deceased donor, rinsed in normal saline, preserved in a cryopreservative solution, and then frozen by gradually decreasing the temperature using liquid nitrogen or similar method. The implant may be thawed in normal saline solution and then implanted in a patient in need of a vertebral disk replacement.
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| 79. |
(WO 2008/014612) FUSION PROTEINS AND METHODS FOR MODULATION OF IMMUNE RESPONSE
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07.02.2008
|
C12N 15/62
|
PCT/CA2007/001356
|
MCGILL UNIVERSITY
|
| |
A fusion protein comprising GM-CSF and IL-15 is described. The fusion protein has unexpected immune suppressive properties and is useful in a variety of therapeutic applications.
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| |
|
| 80. |
(WO 2008/014570) TREATMENT AND PREVENTION OF ALLERGIC AIRWAYS DISEASES
|
07.02.2008
|
A61K 39/09
|
PCT/AU2007/001098
|
THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES (TUNRA) LIMITED
|
| |
The present invention provides a method for the treatment or prevention of an allergic airways disease in a subject, the method comprising administering to the subject a composition comprising Streptococcus pneumoniae or one or more antigens derived therefrom. Also provided are methods and compositions for inducing protective immunity against an allergic airways disease, suppressing an allergic immune response, and treating or preventing conditions such as eosinophilia, mucous secreting cell expression, airway hyperresponsivenss and Th2-mediated disease.
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| 81. |
(WO 2008/014550) MARKERS FOR PIGMENTATION
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07.02.2008
|
C12N 15/11
|
PCT/AU2007/001070
|
THE UNIVERSITY OF SYDNEY
|
| |
The present invention relates to a genetic marker for distinguishing animals that have a trait of pigmentation, wherein said marker is a polymorphism in the tyrosinase- related protein gene, and use thereof in prediction, selection, breeding and identification of pigmentation.
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