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| Title |
Pub. Date |
Int. Class |
App. Num |
Applicant |
| 1. |
(WO 2007/150066) FLUIDIC SELF-ASSEMBLY FOR SYSTEM INTEGRATION
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27.12.2007
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H05K 1/18
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PCT/US2007/072038
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UNIVERSITY OF WASHINGTON
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A method for self-assembly is disclosed that accomplishes the assembly process in one step, obviating or mitigating the need for post-processing of an assembled macro- electronic device. Microcomponents are fabricated having a particular shape, and a template with embedded interconnects is fabricated having recessed binding sites that are sized to receive particular microcomponent types. The binding sites include a low melting point alloy for electrically connecting received microcomponents to the interconnect network. The template is placed in a liquid, and the microcomponents are introduced to the liquid such that the microcomponents flow or slide along the template propelled by gravity and/or fluid-dynamic forces and some of them are rec...
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| 2. |
(WO 2007/150037) SYSTEMS AND METHODS FOR IMPROVING A RESOLUTION OF AN IMAGE
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27.12.2007
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A61B 6/03
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PCT/US2007/071917
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GENERAL ELECTRIC COMPANY
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A method for reconstructing an image in a tomographic imaging system is described. The method includes improving a spatial resolution of the image by iteratively reconstructing the image.
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| 3. |
(WO 2007/150036) EPISOMAL EXPRESSION VECTOR FOR METAZOAN CELLS
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27.12.2007
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C12N 15/00
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PCT/US2007/071911
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UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY
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The invention relates to a vector comprising an origin of replication for episomal maintenance in a metazoan cell, a gene for episomal maintenance in the metazoan cell, and a telomeric polynucleotide sequence. The vector can be used for episomal expression of RNA and polypeptides in metazoan cells.
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| 4. |
(WO 2007/150027) SYSTEM AND METHOD FOR REMOVING A DISSOLVED SUBSTANCE FROM A SOLUTION
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27.12.2007
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C07C 51/43
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PCT/US2007/071897
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KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
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| |
A system for removing a dissolved substance from a solution comprises a channel (10) defining a flow path of the solution, a first set of electrodes (20) proximate an inner surface of the flow path, and a second set of electrodes (22) proximate an inner surface of the flow path. A solution including a plurality of positive ions and a plurality of negative ions is introduced into the channel (10). A first varying electric field is applied to the channel (10) via the first set of electrodes (20) and a second varying electric field is applied to the channel (10) via the second set of electrodes (22). The first and second fields cause at least one region of concentration of positive ions and at least one region of concentration of negative ions...
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| 5. |
(WO 2007/149999) COMPOSITIONS AND METHODS FOR JOINING NON-CONJOINED LUMENS
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27.12.2007
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A61B 17/08
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PCT/US2007/071824
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THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
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| |
Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical techniques.
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| 6. |
(WO 2007/149982) DIAGNOSIS OF AUTOIMMUNE DISEASE
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27.12.2007
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G01N 33/53
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PCT/US2007/071779
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THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
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| |
Methods and compositions for diagnosing and treating autoimmune disease, e.g., acute disseminated encephalomyelitis (ADEM), are described.
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| 7. |
(WO 2007/149956) METHOD AND APPARATUS FOR CONTROLLING CARRIER ENVELOPE PHASE
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27.12.2007
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H01S 3/13
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PCT/US2007/071731
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KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
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A chirped pulse amplification laser system The system generally comprises a laser source (12), a pulse modification apparatus (18) including first and second pulse modification elements separated by a separation distance, a positioning element (24s), a measurement device (22), and a feedback controller (26), The laser source (12) is operable to generate a laser pulse a the pulse modification apparatus operable to modify at least a portion of the laser pulse The positioning element (24s) is operable to reposition at least a portion of the pulse modification apparatus to vary the separation distance, The measurement device (22) is operable to measure the carrier envelope phase of the generated laser pulse and the feedback controller (26) is o...
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| 8. |
(WO 2007/149938) METHODS FOR PROMOTING HAIR GROWTH
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27.12.2007
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A61K 38/12
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PCT/US2007/071695
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THE SALK INSTITUTE BIOLOGICAL STUDIES
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This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure.
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| 9. |
(WO 2007/149875) COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND/OR REVERSING TYPE-1 DIABETES
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27.12.2007
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A61K 39/395
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PCT/US2007/071588
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THE CURATORS OF THE UNIVERSITY OF MISSOURI
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| |
The present invention relates generally compounds, compositions, combinations, kits, and methods for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes, or reversal of type 1 diabetes or stimulation of production of endogenous insulin.
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| 10. |
(WO 2007/149870) TWO-COLOR FLUORESCENT REPORTER FOR ALTERNATIVE PRE-MRNA SPLICING
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27.12.2007
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C12Q 1/68
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PCT/US2007/071582
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
The present invention provides reporter constructs for in vivo or in vitro monitoring of alternative pre-mRNA splicing events. The reporter constructs described herein are also particularly useful for high-throughput screening of compounds that affect alternative pre-mRNA splicing. Kits comprising the reporter constructs of the present invention find utility in a wide range of applications including, for example, basic research, drug screening, and drug design.
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| 11. |
(WO 2007/149868) CONTROLLED RELEASE ENCAPSULATED ANTI-BACTERIAL AND ANTI-INFLAMMATORY NANOPARTICLES
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27.12.2007
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A61K 9/14
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PCT/US2007/071580
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
This invention pertains to the formulation of nanoparticles that have intrinsic antimicrobial and anti-inflammatory activity. The nanoparticles can be impregnated with one or more therapeutic agents and thereby enhance the antimicrobial and/or anti-inflammatory activity of such agents, and also other properties that the therapeutic agents provide.
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| 12. |
(WO 2007/149865) METHODS AND COMPOSITIONS RELATED TO INHIBITION OF CERAMIDE SYNTHESIS
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27.12.2007
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A61K 31/715
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PCT/US2007/071576
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UNIVERSITY OF UTAH RESEARCH FOUNDATION
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Disclosed are compositions and methods related to the ceramide synthesis pathway and various diseases and disorders associated therewith, such as insulin resistance and inflammation.
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| 13. |
(WO 2007/149817) COMBINATIONS OF BIOLOGICAL CONTROL AGENTS WITH A NEMATICIDAL SEED COATING
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27.12.2007
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A01N 25/26
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PCT/US2007/071467
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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This invention provides combinations of at least one biological control agent and at least one nematicide to enhance plant protection against pests and pathogens.
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| 14. |
(WO 2007/149782) SELECTIVE INHIBITORS FOR TRANSFERASES
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27.12.2007
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A61K 31/00
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PCT/US2007/071351
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UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
|
| |
A pharmaceutical composition comprising a compound of formula I or II and a pharmaceutically acceptable carrier. Methods for treating a proliferative disorder mediated by a methyl transferase comprising administering an anti-proliferative effective amount of the compound of formula I or II are also presented.
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| 15. |
(WO 2007/149725) METHOD AND SYSTEM FOR AUTONOMOUS CONTROL AND PROTECTION OF COMPUTER SYSTEMS
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27.12.2007
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G06F 12/14
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PCT/US2007/070903
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THE ARIZONA BOARD OF REGENTS, on behalf of THE UNIVERSITY OF ARIZONA
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| |
A management system includes a plurality of components within a computer system. A plurality of component resource managers is provided, and each of the components is controlled by at least one of the plurality of component resource managers. A plurality of component management interfaces is also provided. Each of the components communicates with at least one of the controlling component resource managers via one of the component management interfaces. At least one runtime manager autonomously controls operation of the components and the component resource managers.
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| 16. |
(WO 2007/149657) ANTIFUNGAL POLYPEPTIDES
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27.12.2007
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C07K 14/385
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PCT/US2007/068984
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PIONEER HI-BRED INTERNATIONAL, INC.
|
| |
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from fungal fermentation broths. Nucleic acids that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism...
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| 17. |
(WO 2007/149583) ACYLTRANSFERASES FOR ALTERING LIPID PRODUCTION ON PLANTS
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27.12.2007
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A01H 5/00
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PCT/US2007/014690
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THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY
|
| |
The present invention relates to compositions comprising acyltransferase nucleic acid molecules for altering lipids on the surface of plants, and related methods. In particular, the present invention provides compositions and methods for increasing the amount of free fatty acids, acylglycerols, and other lipids on the surface of a plant. In a preferred embodiment, the present invention relates to increasing activity of a GPAT acyltransferase for altering lipid on the plant surface, for increasing surface lipids, for enhancing environmental stress tolerance, increasing resistance to biotic stress, and providing novel plant lipids for commercial products. In further embodiments, the present invention relates to using an Arabidopsis thaliana G...
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| 18. |
(WO 2007/149567) TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES
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27.12.2007
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C07K 14/435
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PCT/US2007/014602
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MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
|
| |
The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age- related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
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| 19. |
(WO 2007/149559) MAGNETICALLY COUPLEABLE ROBOTIC DEVICES AND RELATED METHODS
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27.12.2007
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A61B 19/00
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PCT/US2007/014567
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BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
|
| |
The present invention relates to magnetically coupleable robotic surgical devices. More specifically, the present invention relates to robotic surgical devices that can be inserted into a patient's body and can be positioned within the patient's body using an external magnet.
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| 20. |
(WO 2007/149554) METHODS FOR RESTORING NEURAL FUNCTION
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27.12.2007
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C12N 5/08
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PCT/US2007/014552
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THE JOHNS HOPKINS UNIVERSITY
|
| |
The present invention features therapeutic strategies featuring cellular and pharmacological compositions and related methods to enhance functional recovery in spinal cord injury and motor neuron disease.
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| 21. |
(WO 2007/149550) MODULATION OF DIFFERENTIATION AND CELL FUNCTION VIA FOX01 AND NOTCH SIGNALING
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27.12.2007
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G01N 33/53
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PCT/US2007/014537
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
|
| |
Methods of identifying compounds useful for regulating differentiation via interactions with FoxOl are provided.
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| 22. |
(WO 2007/149544) MULTI-PURPOSE CONCENTRATION SENSORS AND TEST METHODS
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27.12.2007
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A61M 1/00
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PCT/US2007/014503
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THE UNIVERSITY OF MIAMI
|
| |
A multi-purpose concentration sensor (MPCS) for organic compounds/gases or other compounds/gases tests the concentration of target content of the compound/gas such as methanol dissolved in certain solvents like water, where the exemplary methanol solution is called target solution, where the sensor can optionally or alternatively test the concentration of gas state target content like methanol vapor in a gas mixture and where the gas mixture to be tested is called target gas. The MPCS comprises two chambers or flow passages, a 'separate' structure, one or more diffusion or transport structures, one or more transfer structures, optionally includes one or more temperature control structures, one or more aim sensors, and optionally, one or mor...
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| 23. |
(WO 2007/149541) METHODS FOR MAKING CARBIDE-METAL NANOCOMPOSITE POWDERS
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27.12.2007
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C23C 8/00
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PCT/US2007/014498
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UNIVERSITY OF UTAH RESEARCH FOUNDATION
|
| |
This chemical vapor synthesis process was designed so that a metal carbide precursor and a secondary metal precursor are separately or together fed into each evaporator in a reactor by specially designed precursor feeders, either simultaneously or sequentially. The reduction and carburization of the vaporized precursors by gaseous mixtures produces carbide-metal nanocomposite powders. The product can be a very uniform mixture of the constituent powders or a uniform agglomerate, which is important to ensure a high quality of bulk cemented metal carbide product after consolidation and sintering. These nanocomposite powders can be readily characterized using XRD, carbon anal zer and TEM.
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| 24. |
(WO 2007/149534) METHODS OF POLARIZATION ENGINEERING AND THEIR APPLICATIONS
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27.12.2007
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G12B 21/06
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PCT/US2007/014480
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UNIVERSITY OF DAYTON
|
| |
Special polarization states are generated that have unique focusing properties that may be used to create extremely strong longitudinal fields. Combined with surface plasmon excitation, these polarization states can be used in apertureless near-field scanning optical microscopy systems. A radially polarized beam is directed into a plasmon-generating optical fiber comprising a metal coated, tapered, apertureless tip. The apertureless tip excites surface plasmon waves and direct the surface plasmon waves to the tip when a radially polarized beam propagates along the plasmon-generating optical fiber. An objective lens collects the near field optical signals from a sample positioned adjacent to the apertureless. Potential spatial resolution of ...
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| 25. |
(WO 2007/149521) NUCLEOTIDE MOTIFS PROVIDING LOCALIZATION ELEMENTS AND METHODS OF USE
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27.12.2007
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C07H 21/02
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PCT/US2007/014444
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THE JOHNS HOPKINS UNIVERSITY
|
| |
The instant invention describes nucleotide motifs comprising a localization element and small RNA molecules comprising the localization motifs, and methods of use in gene silencing. The nucleotide motifs have use in preventing and treating diseases or disorders.
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