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| Title |
Pub. Date |
Int. Class |
App. Num |
Applicant |
| 51. |
(WO 2007/123801) FILAMENTOUS FUNGI HAVING REDUCED UDP-GALACTOFURANOSE CONTENT
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01.11.2007
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C12N 9/90
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PCT/US2007/008067
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GENENCOR INTERNATIONAL, INC.
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A filamentous fungal cell having reduced UDP-galactofuranose is provided. The fungal cell may, in certain embodiments, contain a nuclear genome comprising an inactivated UDP-galactopyranose mutase (UDP-galp mutase) gene and a recombinant nucleic acid for expression of a protein. Also provided are methods of producing a protein using the subject fungal cell, as well as methods of producing the subject fungal cell.
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| 52. |
(WO 2007/123799) ASSESSING SUBJECT'S REACTIVITY TO PSYCHOLOGICAL STRESS USING FMRI
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01.11.2007
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A61B 5/05
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PCT/US2007/008065
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THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
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This invention relates to the use of a quantitative functional MRI (fMRI) - arterial spin-labeling perfusion MRI or absolute T2 mapping MRI or a combination thereof in the non-invasive neuroimaging of a subject's brain in response to stress-inducing psychological stimuli, which can be utilized to predict individual stress reactivity as well as to be used as a human model for testing or optimizing psychopharmacological agents.
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| 53. |
(WO 2007/123777) INHIBITION OF HIF-1 ACTIVATION FOR ANTI-TUMOR AND ANTI-INFLAMMATORY RESPONSES
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01.11.2007
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A61K 38/43
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PCT/US2007/008034
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DUKE UNIVERSITY
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The presently disclosed subject matter generally relates to methods and compositions for inhibiting the expression and/or activation of hypoxia-inducible factor 1 (HIF-1) genes in a hypoxic cell. More particularly, the methods disclosed herein relate to inhibition of HIF-1 activation in a cell, increasing sensitivity of a tumor cell to radiation and/or chemotherapy, delaying tumor growth, inhibiting tumor blood vessel growth, inhibiting inflammatory responses in a cell through the use of compositions that prevent the nitrosylation of HIF-1, and methods for screening for new inhibitors of HIF-1 activiation. Additionally, the compositions disclosed herein relate to compositions that can be employed in, and are identified by, the disclosed met...
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| 54. |
(WO 2007/123776) METHODS AND SYSTEMS FOR GASIFYING A PROCESS STREAM
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01.11.2007
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C01B 3/36
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PCT/US2007/008033
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
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Methods and systems for gasifying process streams are described. In some embodiments, a method for gasifying a process stream includes gasifying the process stream in a first chamber to generate one or more product gases, transporting at least a portion of the one or more product gases to a second chamber, combusting at least a portion of the one or more product gases in the presence of one or more catalysts in the second chamber to generate a heat energy, and indirectly providing the heat energy from the second chamber to the first chamber as a primary heat source to drive gasification of the process stream.
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| 55. |
(WO 2007/123771) IGE DIRECTED DNA VACCINATION
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01.11.2007
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A61K 47/48
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PCT/US2007/008028
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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This invention is directed to a approach for focusing and expressing DNA vaccinates in Antigen Presenting Cells (APCs) mediated through targeting IgE receptors (FcεRs) on APC and driving DNA expression through provision of an APC specific regulatory element This vaccine can be used in the prevention or treatment of allergic disease.
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| 56. |
(WO 2007/123766) SPREAD-SPECTRUM RECEIVER AND RECEPTION METHOD
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01.11.2007
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H04B 1/00
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PCT/US2007/008022
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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Receivers and reception methods conduct spread spectrum reception using the energy of multiple bits, preferably a substantial number of bits, in a packet for correct alignment of the spreading code at the receiver. Code acquisition, as well as packet detection and acquisition are provided by embodiments of the invention. Preferred embodiment receivers and reception methods provide packet detection at low SINR looking at energy of multiple bits of the packet, frame synchronization using short preamble, timing recovery at low SINR looking at energy of multiple bits of the packet, quick code acquisition using parallel search for all possible code phases, code acquisition at low SlNR, and tracking of acquired timing and code phase. Preferred em...
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| 57. |
(WO 2007/123737) METHODS AND COMPOSITIONS FOR LOCALIZED SECRETION OF ANTI-CTLA-4 ANTIBODIES
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01.11.2007
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C12N 15/63
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PCT/US2007/007983
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UNIVERSITY OF CALIFORNIA
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The present invention provides compositions and methods for effectuating the localized expression of anti-CTLA-4 antibody proximal to a target tissue in a patient.
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| 58. |
(WO 2007/123732) ANTIFUNGAL AND ANTIPARASITIC INDOLOQUINOLINE DERIVATIVES
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01.11.2007
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A61K 31/4738
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PCT/US2007/007976
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FLORIDA A & M UNIVERSITY
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A compound having the formula: (I), (II), (III), or (IV) wherein: R is an electron withdrawing or electron moiety; R<sb>5</sb> and R<sb>10</sb> may be the same or different and are a straight or branched 1-5 carbon or heteroatom chain substituted terminally by a cycloalkyl or aromatic ring, or other structural isomer or complex thereof; n is the position of substitution of R; Z is N-R<sb>10</sb>, O, S, S=O, CH<sb>2</sb> or C=O; y is 1-5 and Q is Z or NH, with the proviso that, where Z is NH, N-CH<sb>3</sb>, S or O and R<sb>n</sb> is H, R<sb>5</sb> may not be CH<sb>3</sb>; as well as ...
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| 59. |
(WO 2007/123726) PROBE BAR REMOVER
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01.11.2007
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B21F 9/00
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PCT/US2007/007969
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UNIVERSITY OF UTAH RESEARCH FOUNDATION
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A probe bar remover (10) for loosening and removing probe bars from the ground includes an elongated member (12) with an engagement end and a handling end. The elongated member (12) also includes a foot plate (18) along the elongated member (12) oriented toward the handling end. A bar engagement member (20) is coupled to the elongated member (12) at the engagement end and can include an engagement gap (22) for engaging a probe bar (15). A fulcrum (24) can be oriented along the elongated member (12), which contacts a ground surface, and a handlebar (26) is removably coupled to the handling end of the elongated member. To remove probe bars from a ground surface, the probe bar remover (10) can be engaged with an exposed portion of a probe bar ...
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| 60. |
(WO 2007/123721) METHODS OF DETECTING AND CONTROLLING MUCOID PSEUDOMONAS BIOFILM PRODUCTION
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01.11.2007
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C12Q 1/02
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PCT/US2007/007964
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MARSHALL UNIVERSITY RESEARCH CORPORATION
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Compositions and methods for detecting and controlling the conversion to mucoidy in Pseudomonas aeruginosa are disclosed. The present invention provides for detecting the switch from nonmucoid to mucoid state of P. aeruginosa by measuring mucE expression or MucE protein levels. The interaction between MucE and AIgW controls the switch to mucoidy in wild type P. aeruginosa. Also disclosed is an alginate biosynthesis heterologous expression system for use in screening candidate substances that inhibit conversion to mucoidy.
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| 61. |
(WO 2007/123691) METHOD FOR TREATING BLOOD COAGULATION DISORDERS
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01.11.2007
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A61K 9/127
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PCT/US2007/007924
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THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
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Provided is a method for treatment of blood coagulation disorders. The method comprises administering to an individual compositions comprising lipidic particles comprising phopatidylcholine, phosphatidylinositol and cholesterol. One or more peptides, polypeptides or proteins involved in the blood coagulation cascade are associated with the lipidic particles.
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| 62. |
(WO 2007/123685) SYSTEM AND METHOD FOR PROTECTING COMMUNICATION DEVICES FROM DENIAL OF SERVICE ATTACKS
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01.11.2007
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H04L 9/00
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PCT/US2007/007916
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AUBURN UNIVERSITY
|
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A system for preventing successful denial of service attacks comprises a first communication device, a second communication device, and a network. The first and second communication devices establish a communication session via the network. Based on various information, such as a pre-shared secret, one of the communication devices determines a network access filter value and compares this value to at least one data frame in order to authenticate such data frame without committing significant computing resource and any memory space. By updating the network access filter over time, an unauthorized user who discovers the outdated network access filter values is prevented from successfully launching a denial of service attack.
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| 63. |
(WO 2007/123680) METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE AND IMPROVING NORMAL MEMORY
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01.11.2007
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G01N 33/53
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PCT/US2007/007908
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
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The disclosure relates generally to neurodegenerative disorders and more specifically to a group of presenilin/G-protein/c-src binding polypeptides and methods of use for modulating signaling and progression of Alzheimer's disease.
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| 64. |
(WO 2007/123675) CRYSTAL STRUCTURE OF HUMAN GPVI AND APPLICATIONS THEREOF
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01.11.2007
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C07K 14/00
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PCT/US2007/007900
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UNIVERSITY OF CINCINNATI
|
| |
A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.
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| 65. |
(WO 2007/123667) MEMBRANE-PERMEANT PEPTIDE COMPLEXES FOR TREATMENT OF SEPSIS
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01.11.2007
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A61K 39/00
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PCT/US2007/007892
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WASHINGTON UNIVERSITY
|
| |
Methods and compositions for treating sepsis and diseases and conditions involving cellular apoptosis using cell membrane-permeant peptide conjugates of a cell membrane permeant peptide together with anti-apoptotic domains of the TCL1 protein are provided.
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| 66. |
(WO 2007/123637) OLIGOMERIC POLYOLS FROM PALM-BASED OILS AND POLYURETHANE COMPOSITIONS MADE THEREFROM
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01.11.2007
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C08G 18/36
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PCT/US2007/007657
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PITTSBURG STATE UNIVERSITY
|
| |
The invention relates to oligomeric polyols that are made from palm-based oils and to polyurethane compositions comprising the oligomeric palm-based polyols. Oligomeric polyols of the invention comprise a ring-opened and oligomerized epoxidized palm-based oil composition comprising about 40% wt. or greater oligomers, a hydroxyl number of about 65 or less, a number average hydroxyl functionality (fn) of about 2.5 or less, and a viscosity at 25° C of about 4 Pa-s or less.
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| 67. |
(WO 2007/123586) BIOMIMETIC MICROFABRICATED COMPOUND EYES
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01.11.2007
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G03H 1/00
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PCT/US2007/001381
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
An artificial compound eye comprising a plurality of three-dimensional (3D) self-aligned polymer microlenses disposed on a curvilinear surface; and a plurality of waveguides, wherein each of the waveguides is in optical communication with one of the plurality of polymer microlenses.
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| 68. |
(WO 2007/123536) BIODEGRADABLE POLYURETHANES
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01.11.2007
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C08G 18/10
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PCT/US2006/015485
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CARNEGIE MELLON UNIVERSITY
|
| |
A method for preparing biodegradable polyurethanes includes contacting a flowable quasi-prepolymer including free aliphatic polyisocyanate compounds with a polyester polyol hardener having a functionality of at least two to form a reactive liquid mixture. The quasi-prepolymer can, for example, be formed by contacting a polyisocyanate component comprising at least one aliphatic polyisocyanate compound with a polyol component comprising at least one polyol compound to form an adduct of the polyisocyanate component and the polyol component wherein a sufficient excess of the polyisocyanate component is used to form the quasi-prepolymer.
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| 69. |
(WO 2007/123518) MULTIPLE IMAGING AND/OR SPECTROSCOPIC MODALITY PROBE
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01.11.2007
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A61B 5/00
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PCT/US2006/014988
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CEDARS-SINAI MEDICAL CENTER
|
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The apparatus and methods described herein enable an operator to simultaneously collect images and spectroscopic information from a region(s) of interest using a multiple modality imaging and/or spectroscopic probe, configured as a catheter, endoscope, microscope, or hand held probe. The device may incorporate, for example, an ultrasonic transducer and a fiber optic probe to translate images and spectra. The apparatus and methods may be used in any suitable cavity, for example, the vascular system of a mammal.
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| 70. |
(WO 2007/123503) BISMUTH OXYFLUORIDE BASED NANOCOMPOSITES AS ELECTRODE MATERIALS
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01.11.2007
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C01B 11/24
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PCT/US2006/005908
|
RUTGERS, THE STATE UNIVERSITY
|
| |
The present invention relates to bismuth oxyfluoride nanocomposites used as positive electrodes in primary and rechargeable electromechanical energy storage systems.
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| 71. |
(WO 2007/123496) METHOD OF ZINC OXIDE FILM GROWN ON THE EPITAXIAL LATERAL OVERGROWTH GALLIUM NITRIDE TEMPLATE
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01.11.2007
|
H01L 21/00
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PCT/SG2007/000117
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NATIONAL UNIVERSITY OF SINGAPORE
|
| |
A growth method is proposed for high quality zinc oxide comprising the following steps: (1) growing a gallium nitride layer on a sapphire substrate around a temperature of 10000 C; (2) patterning a SiO2 mask into stripes oriented in the gallium nitride <1 l100> or direction; (3) growing epitaxial lateral overgrowth of (ELO) gallium nitride layers by controlling the facet planes via choosing the growth temperature and the reactor; (4) depositing zinc oxide films on facets ELO gallium nitride templates by chemical vapor deposition (CVD). Zinc oxide crystal of high quality with a reduced number of crystal defects can be grown on a gallium nitride template. This method can be used to fabricate zinc oxide films with low dislocation density lowe...
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| 72. |
(WO 2007/123495) METHOD OF PATTERNING AND PRODUCT(S) OBTAINED THEREFROM
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01.11.2007
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C08J 5/18
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PCT/SG2007/000116
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NATIONAL UNIVERSITY OF SINGAPORE
|
| |
The present invention provides a method of patterning, the method comprising the steps of: (a) providing a porous film; and (b) adding at least one structure to the porous film. The present invention also provides a patterned film prepared according to the method of the invention. The present invention also provides a method of preparing a porous film, and a porous film prepared according to the method of the invention.
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| 73. |
(WO 2007/123488) RECOMBINANT LACTOBACILLUS AND USE OF THE SAME
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01.11.2007
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C12N 1/21
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PCT/SG2007/000090
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NATIONAL UNIVERSITY OF SINGAPORE
|
| |
The invention relates to recombinant lactobacillus, use of the same and a pharmaceutical composition including the same. The recombinant lactobacillus includes a heterologous nucleic acid sequence. The heterologous nucleic acid sequence encodes at least an immunogenic fragment of the mite allergens Der p 1, Der p 2, or Blo t 5, or an immunogenic homolog thereof. A respective fragment of Der p 1 includes at least 8 % of the amino acid sequence of the mite allergen. A method of modulating the immune response to an allergen in a mammal as well as a pharmaceutical composition and a kit are also disclosed.
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| 74. |
(WO 2007/123356) THE FACILITATED OLEFIN TRANSPORTING COMPOSITE MEMBRANE COMPRISING NANOSIZED METAL AND IONIC LIQUID
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01.11.2007
|
B01D 71/00
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PCT/KR2007/001991
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INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
|
| |
Disclosed is a composite membrane, comprising metal nanoparticles and ionic liquid. In the composite membrane, the metal nanoparticles are partially cationized (polarized) by the anions of the ionic liquid to act as carriers enabling the facilitated transport of olefin. Thus, the composite membrane enables the selective facilitated transport of olefin in the separation of a mixed gas of olefin and paraffin.
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| 75. |
(WO 2007/123327) DRIVING CIRCUIT FOR SINGLE-PHASE SWITCHED RELUCTANCE MOTOR AND DRIVING METHOD THEREOF
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01.11.2007
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H02P 27/06
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PCT/KR2007/001908
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KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION
|
| |
Disclosed are a driving circuit for a single-phase SRM and a driving method thereof. The driving circuit for the single-phase SRM includes a switched reluctance motor, a voltage source which supplies energy to the switched reluctance motor, and an inverter circuit which is connected to the switched reluctance motor in parallel so as to temporarily store energy of the voltage source, and then supply the energy to the switched reluctance motor.
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