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| Title |
Pub. Date |
Int. Class |
App. Num |
Applicant |
| 76. |
(WO 2007/126805) CANCER IMMUNOTHERAPY COMPOSITIONS AND METHODS OF USE
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08.11.2007
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A61K 35/00
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PCT/US2007/007556
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Cell Genesys, Inc.
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| |
Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, an anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
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| 77. |
(WO 2007/126782) HADRON TREATMENT PLANNING WITH ADEQUATE BIOLOGICAL WEIGHTING
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08.11.2007
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H01J 35/00
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PCT/US2007/007520
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HAMPTON UNIVERSITY
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| |
Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially- dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge reg...
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| 78. |
(WO 2007/126775) COMPOSITIONS AND METHODS FOR MAKING AND USING ACYCLIC N-HALAMINE-BASED BIOCIDAL POLYMERIC MATERIALS AND ARTICLES
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08.11.2007
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A61K 31/74
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PCT/US2007/007506
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BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
|
| |
The present invention includes methods and compositions for providing rechargeable aliphatic N-halamine polymers, monomers, copolymers additives and coatings. The rechargeable aliphatic N-halamine includes an aliphatic N-halamine compound exchangeable associated with one or more halides.
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| 79. |
(WO 2007/126765) ANDROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES
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08.11.2007
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A61K 31/4166
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PCT/US2007/007485
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
A hydantoin compound useful for the prevention or treatment of hyperproliferative diseases or disorders.
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| 80. |
(WO 2007/126764) CHEMICALLY MODIFIED VIRAL CAPSIDS AS TARGETED DELIVERY VECTORS FOR DIAGNOSTIC AND THERAPEUTIC AGENTS
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08.11.2007
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C12N 15/09
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PCT/US2007/007484
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
The present invention provides a novel means of delivering imaging agents and/or therapeutic agents to specific cellular sites in an animal involving the use of a viral capsid that is chemically modified on it exterior and/or interior surfaces.
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| 81. |
(WO 2007/126733) STYRYLPYRIDINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES
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08.11.2007
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C07D 213/16
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PCT/US2007/007400
|
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
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| |
This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
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| 82. |
(WO 2007/126689) ARTICLE FOR PARALLEL LITHOGRAPHY WITH TWO-DIMENSIONAL PEN ARRAYS
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08.11.2007
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G03F 7/00
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PCT/US2007/007186
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NORTHWESTERN UNIVERSITY
|
| |
Massive parallel printing of structures and nanostructures at high speed with high resolution and high quality using two dimensional arrays comprising cantilevers and tip-based transfer of material to a surface. The array is designed so only tips touch the surface. This can be accomplished by long tips and bent cantilevers and alignment. An article comprising: a two-dimensional array of a plurality of cantilevers, wherein the array comprises a plurality of base rows, each base row comprising a plurality of cantilevers, wherein each of the cantilevers comprise tips at the cantilever end away from the base, wherein the number of cantilevers is greater than 250, and wherein the tips have an apex height relative to the cantilever of at least fo...
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| 83. |
(WO 2007/126500) REMOTE CURING OF POLYMER COATING BY GASEOUS, VAPOROUS OR AEROSOL INITIATING AGENT
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08.11.2007
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C04B 16/00
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PCT/US2007/004840
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BOWLING GREEN STATE UNIVERSITY
|
| |
The present invention is a method and apparatus for remote curing of resin- coated surfaces and articles by means of a vaporous curing agent. The method of the present invention includes the steps: (a) providing a surface of the substrate with a layer of a coating precursor comprising a curable material and a stabilized curing agent that is adapted to react with a gaseous, vaporous or aerosol initiating agent to activate the stabilized curing agent so as to cause the curable material to undergo a curing reaction; (b) subjecting the coating precursor to the gaseous, vaporous or aerosol initiating agent for sufficient time to initiate the curing reaction, and allowing the coating precursor to form a cured coating on the substrate. Another var...
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| 84. |
(WO 2007/126457) METHOD AND COMPOSITION FOR TREATING AND PREVENTING TUMOR METASTASIS IN VIVO
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08.11.2007
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C12Q 1/68
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PCT/US2007/002139
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THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
|
| |
Methods, compositions and kits are provided for effectively treating and preventing cancer metastasis in vivo and for increasing survival of subjects burdened with metastatic tumors by targeting a lysyl oxidase or its modulator, especially human lysyl oxidase. Also provided are methods for identifying lysyl oxidase inhibitors and the use of such inhibitors to prevent and treat tumors, particularly metastatic tumors, alone and in combination with chemotherapeutic agents. Further disclosed is the use of lysyl oxidase levels for measuring metastatic potential and survival.
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| 85. |
(WO 2007/126447) SYSTEMS AND METHODS FOR IDENTIFYING PARALLEL DOCUMENTS AND SENTENCE FRAGMENTS IN MULTILINGUAL DOCUMENT COLLECTIONS
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08.11.2007
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G06F 7/00
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PCT/US2007/000853
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UNIVERSITY OF SOUTHERN CALIFORNIA
|
| |
Systems, computer programs, and methods for identifying parallel documents and/or fragments in a bilingual collection are provided. The method for identifying parallel sub-sentential fragments in a bilingual collection comprises translating a source document from a bilingual collection. The method further includes querying a target library associated with the bilingual collection using the translated source document, and identifying one or more target documents based on the query. Subsequently, a source sentence associated with the source document is aligned to one or more target sentences associated with the one or more target documents. Finally, the method includes determining whether a source fragment associated with the source sentence ...
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| 86. |
(WO 2007/126431) USE OF FLUOROCAROBON SURFACTANTS TO IMPROVE PRODUCTIVITY OF GAS AND GAS CONDENSATE WELLS
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08.11.2007
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E21B 43/25
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PCT/US2006/048887
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BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
|
| |
The present invention includes composition having a nonionic, fluorinated polymeric surfactant, water and solvent. Embodiments of compositions according to the present invention are useful, for example, for recovering hydrocarbons from subterranean clastic formations.
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| 87. |
(WO 2007/126418) OPTICALLY INTERFACE ELECTRICALLY CONTROLLED DEVICES
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08.11.2007
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H01L 27/14
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PCT/US2006/042555
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
|
| |
Disclosed are devices and methods for localized control and transport of excitons and separate processing of holes and electrons in a device with an optical input and an optical output. An optoelectronic device includes a coupled or wide quantum well structure. A localized gate is arranged over a region of the coupled or wide quantum well structure and a semiconductor barrier layer. A optical Input and optical output are arranged over other regions of the structure that are separated by the gate electrode region. The coupled or wide quantum well structure is dimensioned and formed from materials that creale a nonzero distance d between the separated electron and hole of an exciton formed in response to the input. The flow of excitons or sep...
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| 88. |
(WO 2007/126412) METHODS OF MAKING SPATIALLY ALIGNED NANOTUBES AND NANOTUBE ARRAYS
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08.11.2007
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D01F 9/12
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PCT/US2006/032125
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THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
|
| |
The present invention provides arrays of longitudinally aligned carbon nanotubes having specified positions, nanotube densities and orientations, and corresponding methods of making nanotube arrays using guided growth and guided deposition methods. Also provided are electronic devices and device arrays comprising one or more arrays of longitudinally aligned carbon nanotubes including multilayer nanotube array structures and devices.
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| 89. |
(WO 2007/126411) BIOCOMPATIBLE POLYMERS AND METHODS OF USE
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08.11.2007
|
C08L 89/00
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PCT/US2006/029754
|
CARNEGIE MELLON UNIVERSITY
|
| |
Compositions and methods for manufacturing polymers are disclosed. Compositions include novel plastics, including films and shaped forms comprising polymer matrices that are biologically compatible and biodegradable. Such plastics may comprise polymers derived from natural sources. Further, such plastics are useful in biological systems for wound repair, implants, stents, drug encapsulation and delivery, and other applications. The disclosed methods comprise mild manufacturing processes such that various additives, such as biologically active proteins, sugars, lipids, and the like may be incorporated into the polymer matrix without subsequent loss of bioactivity during processing. Additionally, methods of manufacture for controlling mechani...
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| 90. |
(WO 2007/126405) AIRFOIL FOR MICRO AIR VEHICLE
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08.11.2007
|
B64C 3/52
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PCT/US2006/011969
|
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC.
|
| |
An airfoil for a micro air vehicle that includes components enabling the airfoil to adjust the angle of attack (AOA) of the airfoil in response to wind gusts, thereby enabling the airfoil to provide smooth flight. The airfoil may include a first compliant region positioned between an inboard section and a first outboard section and may include a second compliant region between a second outboard section and the inboard section. The compliant regions enable the first and second outboard sections to bend about a leading edge section and move relative to an inboard section. This action creates smoother flight due to numerous aerodynamic advantages such as a change in the angle of attack and improved wind gust rejection due to adaptive washout a...
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| 91. |
(WO 2007/126402) METHODS AND COMPOSITIONS RELATED TO HEIGHTENED APOBEC-1 RELATED PROTEIN (ARP) EXPRESSION
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08.11.2007
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C12Q 1/68
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PCT/US2006/004920
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UNIVERSITY OF ROCHESTER
|
| |
Disclosed are methods and compositions related to determining the status and mechanisms underlying long-term nonprogression of viral infections.
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| |
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| 92. |
(WO 2007/126327) WATER REPELLENT ELEMENT AND A METHOD FOR PRODUCING A HYDROPHOBIC COATING
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08.11.2007
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B05D 7/24
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PCT/RU2006/000218
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FACULTY OF PHYSICS, LOMONOSOV MOSCOW STATE UNIVERSITY
|
| |
The invention relates to producing coatings, in particular polymer coatings for rendering hydrophobic rough, porous highly-developed and other substrate having a geometrically complex-shaped surface using supercritical carbon dioxide and is industrially applicable for forming ultrahydrophobic or ultralyophobic coatings on imperfect surfaces. The aim of said invention is to obtain an ultrahydrophobic surface and to increase the water wetting angle of said surface to ≥130° by precipitating a thin and homogeneous polymer coating from a solution of polymer or copolymer in supercritical carbon dioxide on a rough substrate. The inventive method consists in placing the substrate (3) and a weighting portion of polymer or copolymer in a ...
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| 93. |
(WO 2007/126278) HYBRID GENES AND ENZYMES OF GLUCANASE AND DEXTRANSUCRASE, AND PROCESSES FOR PREPARING ISOMALTO-OLIGOSACCHARIDES OR DEXTRAN USING THE SAME
|
08.11.2007
|
C12N 15/09
|
PCT/KR2007/002106
|
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
|
| |
Disclosed are hybrid genes of glucanase and dextransucrase, recombinant vectors comprising said hybrid genes, microorganisms which are transformed with said recombinant vectors, hybrid enzymes which are expressed from said hybrid genes, and processes for preparing isomalto- oligosaccharides or dextran using said microorganisms or enzymes. Expensive isomalto-oligosaccharides and low molecular weight dextran for clinical use can be produced simply and effectively from cheap substrate, sucrose, using a single bacterial strain or enzyme.
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| 94. |
(WO 2007/126222) PROTON CONDUCTIVE COMPOSITE MEMBRANE COMPRISING SURFACTANT AND INORGANIC FILLER, AND FUEL CELL COMPRISING THE SAME
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08.11.2007
|
H01M 8/02
|
PCT/KR2007/001794
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INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY
|
| |
The present invention relates to proton conductive polymer composite membranes comprising surfactants to contribute to homogeneous distribution of inorganic fillers and to form peculiar microstructures, and inorganic fillers to induce various improved membrane properties, and fuel cells comprising the same. In particular, the present invention relates to proton conductive polymer composite membranes including surfactants such as copolymers of polyethylene oxides and/or polypropylene oxides and oligomers of polyethylene oxides and/or polypropylene oxides; and inorganic fillers such as inorganic oxides, heteropolyacids, or mixtures of inorganic oxides and heteropoly acids.
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| 95. |
(WO 2007/126188) COMPOSITION FOR TREATING URINARY INCONTINENCE COMPRISING UMBILICAL CORD BLOOD STEM CELLS
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08.11.2007
|
A61K 35/44
|
PCT/KR2006/004188
|
CHABIOTECH CO., LTD.
|
| |
Provided is a composition for treating urinary incontinence, comprising umbilical cord blood stem cells and a pharmaceutically acceptable carrier.
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| 96. |
(WO 2007/126163) B CELL-BASED VACCINE LOADED WITH THE LIGAND OF NATURAL KILLER T CELL AND ANTIGEN
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08.11.2007
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A61K 39/02
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PCT/KR2006/001589
|
SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION
|
| |
The present invention relates to a B cell -based vaccine loaded with the ligand of natural killer T cell and antigen for the prevention and treatment of disease, more precisely, an immunotherapeutic and prophylactic vaccine mediated by B cells loaded with α-galactosylceramide, a kind of glycolipid which can stimulate natural killer T cells. A vaccine composition of the present invention can be effectively used as an antitumor immunotherapeutic agent. B cells therein, which are easily obtainable compared with dendritic cells, not only induce a similar level of cytotoxic T lymphocyte response to that of the conventional dendritic cell -based vaccine but also have a prophylactic and therapeutic effect on solid tumor and metastatic tumor.
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| 97. |
(WO 2007/126153) METHOD FOR MANUFACTURING GAS DIFFUSION ELECTRODE, GAS DIFFUSION ELECTRODE, AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING THE GAS DIFFUSION ELECTRODE
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08.11.2007
|
H01M 4/86
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PCT/JP2007/059554
|
UNIVERSITY OF YAMANASHI
|
| |
Hydrogen ions produced in an anode catalyst layer can be efficiently conducted to an electrolyte membrane by adopting a gas diffusion layer and/or a catalyst layer, comprising an ion-conductive polymer material (an ionomer) substantially evenly covering the inner wall of pores (primary pores)within primary aggregates of carbon on which a metal catalyst has been support. Further, hydrogen ions can be allowed to efficiently arrive at a cathode catalyst layer, a lowering in material diffusion speed of oxygen and water as a reactant and a product in the cathode electrode can be suppressed, and the percentage utilization of the metal catalyst canbe improved.
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| 98. |
(WO 2007/126150) NOVEL COMPOSITION FOR TREATING CANCER
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08.11.2007
|
A61K 48/00
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PCT/JP2007/059548
|
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
|
| |
A medicinal composition for treating cancer which contains, as the active ingredient, a nucleic acid, for example, a nucleic acid containing the sequence of the 3'-side half of intron 3 of OncomiR-1/C13orf25 occurring in a human chromosome 13q31.3 or a part of the same, an antisense oligonucleotide against miRNA of miR-17-5p and/or miR20 occurring in the above-described chromosome or the like, wherein the above nucleic acid has an activity of inhibiting the proliferation of cancer, wherein miR-17-5p and/or miR20 are overexpressed, and inducing cell death thereof.
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| 99. |
(WO 2007/126141) IONIZING METHOD AND DEVICE BY ELECTROSPRAY
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08.11.2007
|
G01N 27/62
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PCT/JP2007/059438
|
UNIVERSITY OF YAMANASHI
|
| |
The invention enables measurement of a biosample without preprocessing, desorptive ionization of ions under the atmospheric pressure, and imaging at a spatial resolution of nm order. A sample object of measurement without preprocessing under the atmospheric pressure is, e.g., a biological tissue. An STM probe with an XYZ-axis drive piezoelectric element is vibrated vertically by a Z-direction drive at a frequency of several Hz to several kHz with amplitudes of several 10 μm to several mm, and brought into contact with the biosample at nm order depth to capture molecules of the biosample by the probe tip. A pulse high voltage is applied to the probe tip thereby realizing probe electrospray. The molecules of the sample captured by the p...
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| 100. |
(WO 2007/126115) PREVENTION APPARATUS AND PREVENTION SYSTEM OF OSTEOPOROTIC CHANGE
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08.11.2007
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A61H 23/02
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PCT/JP2007/059366
|
KAGOSHIMA UNIVERSITY
|
| |
An axial vibration stress applying section (7) for applying an axial vibration stress to each bone of a human body (200) is provided, and an axial vibration stress including at least a longitudinal stress or a torsional stress is applied in the body axix directions of the human body (200) from the axial vibration stress applying section (7), thus suppressing action of osteoclast. Consequently, a practitioner can easily perform prevention against osteoporotic change indicative of reduction in amount of bone.
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