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(WO/2002/094979) PRODUCTION OF SECONDARY METABOLITES

(WO/2002/094979) PRODUCTION OF SECONDARY METABOLITES

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2002/094979   International Application No.:  PCT/IB2002/001686
Publication Date:28.11.2002 International Filing Date:17.05.2002
Chapter 2 Demand Filed: 23.12.2002
IPC: C12M 1/12 (2006.01), C12M 1/14 (2006.01), C12M 1/40 (2006.01)
Priority Data:
2001/4268 24.05.2001 ZA
Title: PRODUCTION OF SECONDARY METABOLITES
Abstract: A method of producing a secondary metabolite includes providing an elongate porous substrate with a biofilm of micro-organism and which is arranged with one end of the substrate being at a higher elevation than the other end of the substrate so that the substrate is at an angle to the horizontal. A nutrient solution flows through the substrate, at a rate which is sufficiently low for a nutrient gradient to be established across the biofilm such that the nutrient concentration at a high level along the gradient is sufficiently high to support primary growth of the micro-organism, and the nutrient concentration at a low level along the gradient is sufficiently low to induce secondary growth of the micro-organism. The substrate's angle with the horizontal ensures that any droplets of nutrient permeate forming on the biofilm run towards the lower end of the substrate.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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