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(WO/2009/089359) PYRAZOLOPYRIDINES AS KINASE INHIBITORS

(WO/2009/089359) PYRAZOLOPYRIDINES AS KINASE INHIBITORS

Latest bibliographic data on file with the International Bureau
Pub. No.:  WO/2009/089359   International Application No.:  PCT/US2009/030450
Publication Date:16.07.2009 International Filing Date:08.01.2009
IPC: C07D 471/04 (2006.01), A61K 31/4162 (2006.01), A61P 35/00 (2006.01)
Applicants:ARRAY BIOPHARMA INC. [US/US]; 3200 Walnut Street, Boulder, Colorado 80301 (US) (All Except US).
BLAKE, James [US/US]; (US) (US Only).
GUNAWARDANA, Indrani W. [US/US]; (US) (US Only).
LE HUEROU, Yvan [FR/US]; (US) (US Only).
MOHR, Peter J. [US/US]; (US) (US Only).
WALLACE, Eli M. [US/US]; (US) (US Only).
WANG, Bin [CN/US]; (US) (US Only).
Inventors:BLAKE, James; (US).
GUNAWARDANA, Indrani W.; (US).
LE HUEROU, Yvan; (US).
MOHR, Peter J.; (US).
WALLACE, Eli M.; (US).
WANG, Bin; (US).
Agent:HARRIS, Robert J. et al.; Viksnins Harris & Padys, Customer No. 64483, P.O. Box 111098, St. Paul, Minnesota 55111-1098 (US).
Priority Data:
61/019,865 09.01.2008 US
Title: PYRAZOLOPYRIDINES AS KINASE INHIBITORS
Abstract: Compounds of Formula I are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:English (EN)
Filing Language:English (EN)

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