IPC Definitions - January 01, 2012
G06F 19/10 - Definition
This group covers:
Methods or systems for genetic or protein related data processing in computational molecular biology.
Bioinformatics methods or systems where digital data processing is inherent or implicit, but not explicitly mentioned.
References relevant to classification in this group
This group does not cover:
In silico methods of screening virtual chemical libraries | C40B 30/02 |
In silico or mathematical methods of creating virtual chemical libraries | C40B 50/02 |
Attention is drawn to the following places, which may be of interest for search:
Medical diagnosis | A61B 5/00 |
Manufacture of microarrays, DNA chips | B01J 19/00, C12M 1/34 |
PCR apparatus per se | B01L 7/00, C12M 1/38 |
Macromolecular X-ray crystallographic or NMR structures per se | C07K 14/00 |
Genetic engineering involving nucleic acids | C12N 15/00 |
Chemical reactions involving the use of microarrays, DNA chips | C12Q 1/68 |
Sequencing using PCR | C12Q 1/68 |
Gel electrophoresis apparatus per se | G01N 27/447 |
Sequencing using electrophoresis | G01N 27/447 |
Sequencing using chromatography | G01N 30/00 |
Sequencing using mass spectrometry | G01N 33/68 |
Pattern recognition | G06K 9/00 |
Computer input/output arrangements | G06F 3/00 |
Computer architectures or program control | G06F 9/00 |
Information retrieval, databases per se | G06F 17/30 |
Computer systems using neural network models per se | G06N 3/02 |
Computer systems using knowledge representation per se, e.g. expert systems | G06N 5/02 |
Computer systems using probabilistic models per se | G06N 7/00 |
Finding positions and orientations in microarray images by image processing | G06T 7/00 |
Mass spectrometry apparatus per se | H01J 49/00 |
Special rules of classification
In this group, the first place priority rule is applied, i.e. at each hierarchical level, classification is made in the first appropriate place.
In this group, the following terms or expressions are used with the meaning indicated:
data mining | discovery and analysis of patterns within a vast amount of genetic or protein-related data |
data visualisation | generation and/or display of graphical representations of genetic and protein-related data |
domain | domain of a protein is an element of the overall molecular structure that is self-stabilising and often folds independently of the rest of a polypeptide chain |
drug targeting | drug design strategy aiming at optimising the properties of a medicinal compound, based on the 3-dimensional structure of a target, for delivery to a particular tissue or organ in the body |
fragment assembly | method by which linear portions of sequence information are assembled to obtain full length gene sequence data |
functional genomics | experimental analyses aiming at assessing the function of genes in determining traits, physiology and/or development of an organism, making use of computational and high-throughput technologies |
gene expression | process by which proteins are made or transcribed from the instructions encoded in DNA |
gene expression profiling | determination of the pattern of genes expressed, i.e. transcribed, under specific circumstances or in a specific cell line |
gene finding | method of searching genomic DNA sequences to identify open reading frames which encode proteins |
genome annotation | allocation of functions to individual genes in the genome |
genotype | genetic makeup or profile of an organism with respect to a trait |
genotyping | analysis of an organism's genotype |
haplotype | set of one or more polymorphisms (sequence variations) that may be found at a particular genetic location on the same chromosome |
homology | indication of the amount of similarity between two sequences; homology determinations can include allowance for gaps, insertions, deletions and mismatches between the aligned sequences |
linkage disequilibrium | tendency of alleles located close to each other on the same chromosome to be inherited together |
microarray | plurality of nucleic acid probes attached to a substrate, which form an ordered pattern |
molecular structure | 2-dimensional or 3-dimensional arrangement of atoms, groups of atoms or domains in nucleic aids, proteins, peptides and amino acids |
motif | specific nucleotide or amino acid sequence pattern |
noise correction model | model that accounts for non-signal data, such as for microarrays: optical noise, quality control problems and cross hybridisation |
ontology | classification methodology for formalising a subject’s knowledge in a structured and controlled vocabulary |
orthologue | homologous sequence found in different species and derived from a common ancestor |
paralogue | homologous sequence in the same organism derived from gene duplication |
pedigree | family tree describing the occurrence of heritable traits across generations |
phylogenetic tree | tree-like graphical representation of phylogenetic relationships |
phylogeny | reconstruction of an evolutionary development and history of a species or higher taxonomic grouping of organisms; typically represented as a phylogenetic tree; methods for creating phylogenetic trees |
population genetics | study of genetic variation and genetic evolution of populations |
probe design and optimisation for microarrays | designing and selecting (i) optimal, highly specific probes, e.g. oligonucleotides, cDNA, fragments for hybridisation experiments with microarrays and (ii) optimal sets of probes, e.g. oligonucleotides, cDNA, to be chemically attached to a solid support to form an array |
programming tools or database systems | computer software to assist programming procedures within bioinformatics and database systems for managing genetic/ protein-related data |
protein folding | process by which a polypeptide chain folds into a specific 3-dimensional structure |
proteomics | large-scale study of the functions of proteins and their interactions with other molecular entities in a biological system |
sequence comparison | process of comparing nucleic or amino acid sequences, generally by a linear alignment in such a way that equivalent positions in adjacent sequences are brought into the correct alignment with each other by introducing insertions in suitable positions, in order to identify similarities and/or differences amongst the compared sequences |
sequencing by hybridisation | DNA sequencing technique in which an array of short sequences of nucleotides is brought in contact with a solution of a target DNA sequence, a biochemical method determines a subset of probes that bind to the target sequence and a combinatorial method is then used to reconstruct the DNA sequence from the spectrum |
SNP | single nucleotide polymorphism: a DNA sequence variation that involves a change in a single nucleotide and is commonly present in a part of a population |
structure alignment | form of alignment to establish structural and functional equivalences between two or more proteins based on their secondary or tertiary structures |
syntenic regions | corresponding regions in a species to an observed grouping of genes in the same order and on the same chromosome in another species |
systems biology | simulation and mathematical modelling of relationships and interactions between molecular entities in sub-cellular systems integrating genetic and/or protein-related data to describe the dynamic behaviour of, for example, protein-protein/protein-ligand interactions, regulatory networks and metabolic networks |
taxonomy | classification of organisms to show their evolutionary relationships to other organisms |