| IPC 7 English version |
| C07D-C07D20750 |
C07D 209/00 - C07D 211/98  |
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| SECTION C – CHEMISTRY; METALLURGY |
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| C 07 | ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B 33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B 3/00, C25B 7/00) [2] |
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| C 07 D | HETEROCYCLIC COMPOUNDS [2] |
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| Notes |
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| (1) | This subclass does not cover compounds containing saccharide radicals (as defined in Note (3) following the title of subclass C07H), which are covered by subclass C07H. [2] |
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| (2) | In this subclass, in compounds containing a hetero ring covered by group C07D 295/00 and at least one other hetero ring, the hetero ring covered by group C07D 295/00 is considered as an acyclic chain containing nitrogen atoms. [3] |
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| (3) | In this subclass, the following terms or expressions are used with the meanings indicated: |
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| – | "hetero ring" is a ring having at least one halogen, nitrogen, oxygen, sulfur, selenium, or tellurium atom as a ring member; [2] |
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| – | "bridged" means the presence of at least one fusion other than ortho, peri or spiro; [2] |
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| – | two rings are "condensed" if they share at least one ring member, i.e. "spiro" and "bridged" are considered as condensed; [2] |
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| – | "condensed ring system" is a ring system in which all rings are condensed among themselves; [2] |
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| – | "number of relevant rings" in a condensed ring system equals the number of scissions necessary to convert the ring system into one acyclic chain; [2] |
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| – | "relevant rings" in a condensed ring system, i.e. the rings which taken together describe all the links between every atom of the ring system, are chosen according to the following criteria consecutively: |
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| (a) | lowest number of ring members; |
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| (b) | highest number of hetero atoms as ring members; |
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| (c) | lowest number of members shared with other rings; |
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| (d) | last place in the classification scheme. [2] |
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| (4) | Therapeutic activity of compounds is further classified in subclass A61P. [7] |
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| (5) | In this subclass, in the absence of an indication to the contrary: |
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| (a) | compounds having only one hetero ring are classified in the last appropriate place in one of the groups C07D 203/00 to C07D 347/00. The same applies for compounds having more hetero rings covered by the same main group, neither condensed among themselves nor condensed with a common carbocyclic ring system; [2] |
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| (b) | compounds having two or more hetero rings covered by different main groups neither condensed among themselves nor condensed with a common carbocyclic ring system are classified in the last appropriate place in one of the groups C07D 401/00 to C07D 421/00; [2] |
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| (c) | compounds having two or more relevant hetero rings, covered by the same or by different main groups, which are condensed among themselves or condensed with a common carbocyclic ring system, are classified in the last appropriate place in one of the groups C07D 451/00 to C07D 519/00. [2] |
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| (6) | In this subclass: |
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| – | where a compound may exist in tautomeric forms, it is classified as though existing in the form which is classified last in the system. Therefore, double bonds between ring members and non-ring members and double bonds between ring members themselves are considered equivalent in determining the degree of hydrogenation of the ring. Formulae are considered to be written in Kekulé form; [2] |
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| – | hydrocarbon radicals containing a carbocyclic ring and an acyclic chain by which it is linked to the hetero ring and being substituted on both the carbocyclic ring and the acyclic chain by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, are classified according to the substituents on the acyclic chain. For example, the compound |
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 is classified in group C07D 233/22, and the compound  |
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| is classified in groups C07D 233/24 and C07D 233/26, where X –NH2, –NHCOCH3, or –COOCH3. [2] |
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| (7) | In this subclass, it is desirable to add the indexing codes relating to individual components, chosen according to the guidelines mentioned under (a) to (d) below. The indexing codes, which are chosen as indicated below, have the same numbers as the classification symbols, but a colon is used instead of the oblique stroke, and should be linked. The following guidelines should be followed: |
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| (a) | For compounds classified in groups C07D 203/00 to C07D 347/00 one or more appropriate places which precede the classification place may be given as additional information, e.g. in order to show essential substituents. The appropriate codes are chosen from groups C07D 203/00 to C07D 347/00, with the exception of groups C07D 203/02, C07D 209/06, C07D 209/84, C07D 211/02, C07D 213/08 to C07D 213/14, C07D 213/803 to C07D 213/807, C07D 243/26 to C07D 243/36, C07D 251/56 to C07D 251/62, C07D 295/023, C07D 301/00 to C07D 301/36, C07D 307/08, C07D 307/50 and C07D 311/40. [2] |
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| (b) | In compounds containing two or more hetero rings covered by different main groups, neither condensed among themselves nor with a common carbocyclic ring system, each hetero ring is shown as additional information. The appropriate codes which are chosen from groups C07D 203/00 to C07D 347/00, with the exception of groups C07D 203/02, C07D 209/06, C07D 209/84, C07D 211/02, C07D 213/08 to C07D 213/14, C07D 213/803 to C07D 213/807, C07D 243/26 to C07D 243/36, C07D 251/56 to C07D 251/62, C07D 295/023, C07D 301/00 to C07D 301/36, C07D 307/08, C07D 307/50 and C07D 311/40, are determined by scission of all other hetero rings and considering them as substituents. The locations of the scissions are chosen so as to obtain the substituents which appear in the later place in the Classification, e.g. the relevant rings of |
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 are considered to be  |
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| and the invention information and additional information relating to the said compound would read: |
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| C07D 401/06 // (C07D 401/06, C07D 213:58, C07D 233:24). [2] |
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| (c) | For compounds containing one condensed ring system having two or more relevant hetero rings, and for which no specific group is provided, all relevant rings having hetero atoms as ring members are shown as additional information. These rings are indicated by the main group symbols of groups C07D 203/00 to C07D 347/00, with the exception of groups C07D 207/00, C07D 211/00 to C07D 219/00, C07D 233/00, C07D 295/00, C07D 301/00 and C07D 309/00. [2] |
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| (d) | For compounds containing two or more condensed ring systems each having two or more hetero rings, each condensed system is shown as additional information. The appropriate codes are chosen from groups C07D 451/00 to C07D 517/00, with the exception of groups C07D 463/02 to C07D 463/08, C07D 477/02 to C07D 477/08, C07D 499/04 to C07D 499/20, C07D 501/02 to C07D 501/12, C07D 503/02 to C07D 503/08 and C07D 505/02 to C07D 505/08, and determined by considering separately each condensed system in turn. [2] |
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| (8) | In this subclass, it is desirable to add the indexing codes of subclass C07M. The indexing codes should be unlinked. [6] |
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| (9) | Attention is drawn to Chapter IV of the Guide which sets forth the rules concerning the application and presentation of the different types of indexing code. [6] |
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| Subclass Index |
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| COMPOUNDS CONTAINING ONE HETERO RING |
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| HAVING NITROGEN AS RING HETERO ATOM |
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| only nitrogen atoms |
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| one nitrogen atom |
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| Polymethyleneimine |
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| Preparation of lactams |
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| three-membered ring |
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| four-membered ring |
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| five-membered ring |
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| six-membered ring | C07D 211/00, C07D 213/00, C07D 215/00, C07D 217/00, C07D 219/00, C07D 221/00 |
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| seven-membered ring |
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| Other compounds |
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| two nitrogen atoms |
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| four-membered ring |
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| five-membered ring |
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| six-membered ring |
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| Piperazine |
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| seven-membered ring |
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| Other compounds |
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| three nitrogen atoms |
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| five-membered ring |
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| six-membered ring |
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| Other compounds |
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| four or more nitrogen atoms |
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| nitrogen and oxygen atoms |
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| five-membered ring |
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| six-membered ring |
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| morpholine |
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| Other compounds |
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| nitrogen and sulfur atoms |
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| five-membered ring |
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| six-membered ring |
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| Thiomorpholine |
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| Other compounds |
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| nitrogen, oxygen, and sulfur atoms |
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| HAVING OXYGEN AS RING HETERO ATOM |
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| only oxygen atoms |
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| one oxygen atom |
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| three-membered ring |
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| four-membered ring |
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| five-membered ring |
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| six-membered ring |
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| Other compounds |
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| two oxygen atoms |
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| five-membered ring |
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| six-membered ring |
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| Other compounds |
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| three or more oxygen atoms |
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| Other compounds |
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| oxygen and nitrogen atoms |
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| five-membered ring |
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| six-membered ring |
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| Morpholine |
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| Other compounds |
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| oxygen and sulfur atoms |
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| oxygen, nitrogen and sulfur atoms |
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| HAVING SULFUR AS RING HETERO ATOM |
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| only sulfur atoms |
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| one sulfur atom |
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| five-membered ring |
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| six-membered ring |
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| Other compounds |
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| two or more sulfur atoms |
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| sulfur and nitrogen atoms |
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| five-membered ring |
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| six-membered ring |
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| Thiomorpholine |
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| Other compounds |
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| sulfur and oxygen atoms |
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| sulfur, nitrogen, and oxygen atoms |
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| HAVING SELENIUM OR TELLURIUM AS RING HETERO ATOM |
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| only selenium or tellurium atoms |
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| together with nitrogen atoms |
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| together with oxygen atoms |
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| together with sulfur atoms |
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| HAVING HALOGEN AS RING HETERO ATOM |
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| COMPOUNDS CONTAINING TWO OR MORE HETERO RINGS |
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| IN THE SAME RING SYSTEM |
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| HAVING NITROGEN AS RING HETERO ATOM |
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| only nitrogen |
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| at least one six-membered ring with one nitrogen atom |
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| Tropane, granatane |
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| Quinine, quinuclidine, isoquinuclidine |
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| Emetine, berberine |
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| Lysergic acid, ergot alkaloids |
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| Yohimbine |
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| Vincamine |
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| Carbacephalosporins |
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| Other compounds |
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| Purine |
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| Pteridine |
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| Thienamycin |
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| nitrogen and oxygen |
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| Morphine |
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| Oxapenicillins |
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| Oxacephalosporins |
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| nitrogen and sulfur |
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| Penicillins |
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| Cephalosporins |
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| nitrogen, oxygen, and sulfur |
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| HAVING OXYGEN AS RING HETERO ATOM |
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| only oxygen |
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| oxygen and nitrogen |
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| Morphine |
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| Oxapenicillins |
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| Oxacephalosporins |
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| oxygen and sulfur |
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| oxygen, nitrogen, and sulfur |
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| HAVING SULFUR AS RING HETERO ATOM |
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| only sulfur in a particular ring |
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| sulfur and oxygen |
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| sulfur, nitrogen, and oxygen |
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| HAVING SELENIUM, TELLURIUM, OR HALOGEN AS RING HETERO ATOM |
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| IN DIFFERENT RING SYSTEMS, EACH CONTAINING ONLY ONE HETERO RING |
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| HAVING NITROGEN AS RING HETERO ATOM |
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| only nitrogen |
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| at least one six-membered ring with one nitrogen atom |
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| Other compounds |
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| nitrogen and oxygen |
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| nitrogen and sulfur |
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| thiamine |
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| nitrogen, oxygen, and sulfur |
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| HAVING OXYGEN AS RING HETERO ATOM |
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| only oxygen |
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| oxygen and nitrogen |
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| oxygen and sulfur |
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| oxygen, nitrogen, and sulfur |
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| HAVING SULFUR AS RING HETERO ATOM |
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| only sulfur in a particular ring |
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| sulfur and nitrogen |
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| thiamine |
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| sulfur and oxygen |
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| sulfur, nitrogen, and oxygen |
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| HAVING SELENIUM, TELLURIUM, OR HALOGEN AS RING HETERO ATOM |
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| COMPOUNDS CONTAINING TWO OR MORE RING SYSTEMS, HAVING EACH TWO OR MORE HETERO RINGS |
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| ALKALOIDS |
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| Emetine |
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| Ergot |
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| Granatanine |
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| Morphine |
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| Nicotine |
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| Papaverine |
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| Quinine |
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| Strychnine |
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| Tropa |
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| CEPHALOSPORIN |
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| PENICILLIN |
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| PTERIDINE |
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| THIENAMYCIN |
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| PURINE |
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| THIAMINE |
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| COMPOUNDS CONTAINING UNSPECIFIED HETERO RINGS |
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| Heterocyclic compounds having only nitrogen as ring hetero atom [2] |
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201/ | 00 | Preparation, separation, purification, or stabilisation of unsubstituted lactams [2] |
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201/ | 02 | . | Preparation of lactams [2] |
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201/ | 04 | . | . | from or via oximes by Beckmann rearrangement [2] |
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201/ | 06 | . | . | . | from ketones by simultaneous oxime formation and rearrangement [2] |
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201/ | 08 | . | . | from carboxylic acids or derivatives thereof, e.g. hydroxy carboxylic acids, lactones, nitriles [2] |
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201/ | 10 | . | . | from cycloaliphatic compounds by simultaneous nitrosylation and rearrangement [2] |
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201/ | 12 | . | . | by depolymerising polyamides [2] |
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201/ | 14 | . | Preparation of salts or adducts of lactams [2] |
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201/ | 16 | . | Separation or purification (separation of inorganic salts C01) [2] |
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201/ | 18 | . | Stabilisation [2] |
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203/ | 00 | Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom [2] |
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203/ | 02 | . | Preparation by ring-closure [2] |
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203/ | 04 | . | not condensed with other rings [2] |
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203/ | 06 | . | . | having no double bonds between ring members or between ring members and non-ring members [2] |
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203/ | 08 | . | . | . | with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom [2] |
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203/ | 10 | . | . | . | . | Radicals substituted by singly bound oxygen atoms [2] |
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203/ | 12 | . | . | . | . | Radicals substituted by nitrogen atoms not forming part of a nitro radical [2] |
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203/ | 14 | . | . | . | . | with carbocyclic rings directly attached to the ring nitrogen atom [2] |
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203/ | 16 | . | . | . | with acylated ring nitrogen atoms [2] |
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203/ | 18 | . | . | . | . | by carboxylic acids, or by sulfur or nitrogen analogues thereof [2] |
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203/ | 20 | . | . | . | . | by carbonic acid, or by sulfur or nitrogen analogues thereof, e.g. carbamates [2] |
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203/ | 22 | . | . | . | with hetero atoms directly attached to the ring nitrogen atom [2] |
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203/ | 24 | . | . | . | . | Sulfur atoms [2] |
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203/ | 26 | . | condensed with carbocyclic rings or ring systems [2] |
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205/ | 00 | Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom [2] |
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205/ | 02 | . | not condensed with other rings [2] |
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205/ | 04 | . | . | having no double bonds between ring members or between ring members and non-ring members [2] |
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205/ | 06 | . | . | having one double bond between ring members or between a ring member and a non-ring member [2] |
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205/ | 08 | . | . | . | with one oxygen atom directly attached in position 2, e.g. beta-lactams [2] |
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205/ | 085 | . | . | . | . | with a nitrogen atom directly attached in position 3 [5] |
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205/ | 09 | . | . | . | . | with a sulfur atom directly attached in position 4 [5] |
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205/ | 095 | . | . | . | . | . | and with a nitrogen atom directly attached in position 3 [5] |
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205/ | 10 | . | . | having two double bonds between ring members or between ring members and non-ring members [2] |
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205/ | 12 | . | condensed with carbocyclic rings or ring systems [2] |
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207/ | 00 | Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom [2] |
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| Note |
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| Pyrrolidines having only hydrogen atoms attached to the ring carbon atoms are classified in group C07D 295/00. [2] |
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207/ | 02 | . | with only hydrogen or carbon atoms directly attached to the ring nitrogen atom [2] |
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207/ | 04 | . | . | having no double bonds between ring members or between ring members and non-ring members [2] |
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207/ | 06 | . | . | . | with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms [2] |
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207/ | 08 | . | . | . | with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms [2] |
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207/ | 09 | . | . | . | . | Radicals substituted by nitrogen atoms not forming part of a nitro radical [3] |
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207/ | 10 | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms [2] |
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207/ | 12 | . | . | . | . | Oxygen or sulfur atoms [2] |
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207/ | 14 | . | . | . | . | Nitrogen atoms not forming part of a nitro radical [2] |
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207/ | 16 | . | . | . | . | Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals [2] |
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207/ | 18 | . | . | having one double bond between ring members or between a ring member and a non-ring member [2] |
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207/ | 20 | . | . | . | with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms [2] |
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207/ | 22 | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms [2] |
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207/ | 24 | . | . | . | . | Oxygen or sulfur atoms [2] |
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207/ | 26 | . | . | . | . | . | 2-Pyrrolidones [2] |
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207/ | 263 | . | . | . | . | . | . | with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms [3] |
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207/ | 267 | . | . | . | . | . | . | . | with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom [3] |
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207/ | 27 | . | . | . | . | . | . | . | with substituted hydrocarbon radicals directly attached to the ring nitrogen atom [3] |
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207/ | 273 | . | . | . | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms [3] |
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207/ | 277 | . | . | . | . | . | . | . | Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals [3] |
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207/ | 28 | . | . | . | . | . | . | . | . | 2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles [2,3] |
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207/ | 30 | . | . | having two double bonds between ring members or between ring members and non-ring members [2] |
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207/ | 32 | . | . | . | with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms [2] |
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207/ | 323 | . | . | . | . | with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms [3] |
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207/ | 325 | . | . | . | . | with substituted hydrocarbon radicals directly attached to the ring nitrogen atom [3] |
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207/ | 327 | . | . | . | . | . | Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals [3] |
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207/ | 33 | . | . | . | . | with substituted hydrocarbon radicals, directly attached to ring carbon atoms [3] |
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207/ | 333 | . | . | . | . | . | Radicals substituted by oxygen or sulfur atoms [3] |
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207/ | 335 | . | . | . | . | . | Radicals substituted by nitrogen atoms not forming part of a nitro radical [3] |
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207/ | 337 | . | . | . | . | . | Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals [3] |
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207/ | 34 | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms [2] |
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207/ | 36 | . | . | . | . | Oxygen or sulfur atoms [2] |
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207/ | 38 | . | . | . | . | . | 2-Pyrrolones [2] |
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207/ | 40 | . | . | . | . | . | 2,5-Pyrrolidine-diones [2] |
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207/ | 404 | . | . | . | . | . | . | with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide [3] |
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207/ | 408 | . | . | . | . | . | . | . | Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms [3] |
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207/ | 412 | . | . | . | . | . | . | . | . | Acyclic radicals containing more than six carbon atoms [3] |
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207/ | 416 | . | . | . | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms [3] |
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207/ | 42 | . | . | . | . | Nitro radicals [2] |
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207/ | 44 | . | . | having three double bonds between ring members or between ring members and non-ring members [2] |
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207/ | 444 | . | . | . | having two doubly-bound oxygen atoms directly attached in positions 2 and 5 [3] |
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207/ | 448 | . | . | . | . | with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide [3] |
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207/ | 452 | . | . | . | . | . | with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom [3] |
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207/ | 456 | . | . | . | . | with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms [3] |
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207/ | 46 | . | with hetero atoms directly attached to the ring nitrogen atom [2] |
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207/ | 48 | . | . | Sulfur atoms [2] |
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207/ | 50 | . | . | Nitrogen atoms [2] |
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 | C07D 209/00 - C07D 211/98 |
