(0)C12N:2/3:
IPC6
SECTION C - CHEMISTRY; METALLURGY
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF;...
C12N
3/4
<<   >>   C12N011/00 - C12N015/76  

11
/ 00 Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof [3]

11
/ 02 • Enzymes or microbial cells being immobilised on or in an organic carrier [3]  

11
/ 04 • • entrapped within the carrier, e.g. gel, hollow fibre [3]  

11
/ 06 • • attached to the carrier via a bridging agent [3]  

11
/ 08 • • the carrier being a synthetic polymer [3]  

11
/ 10 • • the carrier being a carbohydrate [3]  

11
/ 12 • • • Cellulose or derivatives thereof [3]  

11
/ 14 • Enzymes or microbial cells being immobilised on or in an inorganic carrier [3]  

11
/ 16 • Enzymes or microbial cells being immobilised on or in a biological cell [3]  

11
/ 18 • Multi-enzyme systems [3]  
 

 13
/ 00 Treatment of micro-organisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves [3]
 

 15
/ 00 Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (mutants or genetically engineered micro-organisms C 12 N 1/00, C 12 N 5/00, C 12 N 7/00; new plants A 01 H; plant reproduction by tissue culture techniques A 01 H 4/00; new animals A 01 K 67/00; use of medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases, gene therapy A 61 K 48/00; peptides in general C 07 K) [3,5,6]

Note
 

This group covers processes wherein there is a modification of the genetic material which would not normally occur in nature without intervention of man which produce a change in the gene structure which is passed on to succeeding generations. [3]

15
/ 01 • Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor [5]  

15
/ 02 • Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion [5]  

15
/ 03 • • Bacteria [5]  

15
/ 04 • • Fungi [5]  

15
/ 05 • • Plant cells [5]  

15
/ 06 • • Animal cells [5]  

15
/ 07 • • Human cells [5]  

15
/ 08 • • Cells resulting from interspecies fusion [5]  

15
/ 09 • Recombinant DNA-technology [5]  

15
/ 10 • • Processes for the isolation, preparation or purification of DNA or RNA (chemical preparation of DNA or RNA C 07 H 21/00; preparation of non-structural polynucleotides from micro-organisms or with enzymes C 12 P 19/34) [5]  

15
/ 11 • • DNA or RNA fragments; Modified forms thereof (DNA or RNA not used in recombinant technology C 07 H 21/00) [5]  

15
/ 12 • • • Genes encoding animal proteins [5]  

15
/ 13 • • • • Immunoglobulins [5]  

15
/ 14 • • • • Human serum albumins [5]  

15
/ 15 • • • • Protease inhibitors, e.g. antithrombin, antitrypsin, hirudin [5]  

15
/ 16 • • • • Hormones [5]  

15
/ 17 • • • • • Insulins [5]  

15
/ 18 • • • • • Growth hormones [5]  

15
/ 19 • • • • Interferons; Lymphokines; Cytokines [5]  

15
/ 20 • • • • • Interferons [5]  

15
/ 21 • • • • • • Alpha-interferons [5]  

15
/ 22 • • • • • • Beta-interferons [5]  

15
/ 23 • • • • • • Gamma-interferons [5]  

15
/ 24 • • • • • Interleukins [5]  

15
/ 25 • • • • • • Interleukin-1 [5]  

15
/ 26 • • • • • • Interleukin-2 [5]  

15
/ 27 • • • • • Colony stimulating factors [5]  

15
/ 28 • • • • • Tumor necrosis factors [5]  

15
/ 29 • • • Genes encoding plant proteins, e.g. thaumatin [5]  

15
/ 30 • • • Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria [5]  

15
/ 31 • • • Genes encoding microbial proteins, e.g. enterotoxins [5]  

15
/ 32 • • • • Bacillus crystal proteins [5]  

15
/ 33 • • • • Genes encoding viral proteins [5]  

15
/ 34 • • • • • Proteins from DNA viruses [5]  

15
/ 35 • • • • • • Parvoviridae, e.g. feline panleukopenia virus, human parvovirus [5]  

15
/ 36 • • • • • • Hepadnaviridae [5]  

15
/ 37 • • • • • • Papovaviridae, e.g. papillomaviruses, polyomavirus, SV40 [5]  

15
/ 38 • • • • • • Herpetoviridae, e.g. herpes simplex virus, varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, pseudorabies virus [5]  

15
/ 39 • • • • • • Poxviridae, e.g. vaccinia virus, variola virus [5]  

15
/ 40 • • • • • Proteins from RNA viruses, e.g. flaviviruses [5]  

15
/ 41 • • • • • • Picornaviridae, e.g. rhinovirus, coxsackie viruses, echoviruses, enteroviruses [5]  

15
/ 42 • • • • • • • Foot-and-mouth disease virus [5]  

15
/ 43 • • • • • • • Poliovirus [5]  

15
/ 44 • • • • • • Orthomyxoviridae, e.g. influenza virus [5]  

15
/ 45 • • • • • • Paramyxoviridae, e.g. measles virus, mumps virus, Newcastle disease virus, canine distemper virus, rinderpest virus, respiratory syncytial viruses [5]  

15
/ 46 • • • • • • Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus [5]  

15
/ 47 • • • • • • Rhabdoviridae, e.g. rabies viruses, vesicular stomatitis virus [5]  

15
/ 48 • • • • • • Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, HIV [5]  

15
/ 49 • • • • • • • Lentiviridae, e.g. immunodeficiency viruses, visna-maedi virus, equine infectious anaemia virus [5]  

15
/ 50 • • • • • • Coronaviridae, e.g. infectious bronchitis virus, transmissible gastroenteritis virus [5]  

15
/ 51 • • • • • Hepatitis viruses [5]  

15
/ 52 • • • Genes encoding for enzymes or proenzymes [5]  

Note
 

In this group:
 

-

 genes encoding for proenzymes are classified with the corresponding genes encoding enzymes;
 

-

 enzymes are generally categorised according to the "Nomenclature and Classification of Enzymes" of the International Commission on Enzymes. Where appropriate, this designation appears in the groups below in parenthesis. [5]

15
/ 53 • • • • Oxidoreductases (1) [5]  

15
/ 54 • • • • Transferases (2) [5]  

15
/ 55 • • • • Hydrolases (3) [5]  

15
/ 56 • • • • • acting on glycosyl compounds (3.2), e.g. amylase, galactosidase, lysozyme [5]  

15
/ 57 • • • • • acting on peptide bonds (3.4) [5]  

15
/ 58 • • • • • • Plasminogen activators, e.g. urokinase, TPA [5]  

15
/ 59 • • • • • • Chymosin [5]  

15
/ 60 • • • • Lyases (4) [5]  

15
/ 61 • • • • Isomerases (5) [5]  

15
/ 62 • • • DNA sequences coding for fusion proteins [5]  

Note
 

In this group, the following term is used with the meaning indicated:
 

-

 "fusion" means the fusion of two different proteins. [5]

15
/ 63 • • Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression [5]  

15
/ 64 • • • General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host [5]  

15
/ 65 • • • using markers (enzymes used as markers C 12 N 15/52) [5]  

15
/ 66 • • • General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease [5]  

Note
 

In this group, the following expression is used with the meaning indicated:
 

-

 "non-functional linkers" means DNA sequences which are used to link DNA sequences and which have no known function of structural gene or regulating function. [5]

15
/ 67 • • • General methods for enhancing the expression [5]  

15
/ 68 • • • • Stabilisation of the vector [5]  

15
/ 69 • • • • Increasing the copy number of the vector [5]  

15
/ 70 • • • Vectors or expression systems specially adapted for E. coli [5]  

Notes

(1)

 This group covers the use of E. coli as host. [5]

(2)

 Shuttle vectors also replicating in E. coli are classified according to the other host. [5]

15
/ 71 • • • • Expression systems using regulatory sequences derived from the trp-operon [5]  

15
/ 72 • • • • Expression systems using regulatory sequences derived from the lac-operon [5]  

15
/ 73 • • • • Expression systems using phage lambda regulatory sequences [5]  

15
/ 74 • • • Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora [5]  

Note
 

This group covers the use of prokaryotes as hosts. [5]

15
/ 75 • • • • for Bacillus [5]  

15
/ 76 • • • • for Actinomyces; for Streptomyces [5]  
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